| 56042463 | 56042486 | 12 | - | 24336569 | HL60 | viability | GAATAGGCTGCACGTGGCCGCGG | RPS26 | ENSG00000197728 | 0.9903265824391139 | [342] | [1441] | 7 | hSpCas9 | negative selection | 2292570 | 56042469 | 56042492 | 12 | - | 24336569 | HL60 | viability | TGCAGCGAATAGGCTGCACGTGG | RPS26 | ENSG00000197728 | 1.377967518008401 | [19] | [109] | 8 | hSpCas9 | negative selection | 2292571 | 56042479 | 56042502 | 12 | - | 24336569 | HL60 | viability | GCACAGTTAGTGCAGCGAATAGG | RPS26 | ENSG00000197728 | 0.12235731977851827 | [658] | [1517] | 1 | hSpCas9 | negative selection | 2292572 | 56042496 | 56042519 | 12 | + | 24336569 | HL60 | viability | CTGTGCCCGATGCGTGCCCAAGG | RPS26 | ENSG00000197728 | -1.7561717717081575 | [256] | [160] | -9 | hSpCas9 | negative selection | 2292573 | 56042501 | 56042524 | 12 | - | 24336569 | HL60 | viability | CTTGTCCTTGGGCACGCATCGGG | RPS26 | ENSG00000197728 | -0.19192074858427471 | [501] | [929] | -2 | hSpCas9 | negative selection | 2292574 | 56042512 | 56042535 | 12 | - | 24336569 | HL60 | viability | TTCTTAATGGCCTTGTCCTTGGG | RPS26 | ENSG00000197728 | -0.3789120906889591 | [839] | [1366] | -3 | hSpCas9 | negative selection | 2292575 | 56042525 | 56042548 | 12 | - | 24336569 | HL60 | viability | TCGAATGACGAATTTCTTAATGG | RPS26 | ENSG00000197728 | 0.060554904243531604 | [202] | [447] | 0 | hSpCas9 | negative selection | 2292576 | 56042535 | 56042558 | 12 | + | 24336569 | HL60 | viability | ATTCGTCATTCGAAACATAGTGG | RPS26 | ENSG00000197728 | 0.23310060584497952 | [549] | [1367] | 2 | hSpCas9 | negative selection | 2292577 | 56042552 | 56042575 | 12 | + | 24336569 | HL60 | viability | TAGTGGAGGCCGCAGCAGTCAGG | RPS26 | ENSG00000197728 | -3.1869312515874553 | [1148] | [266] | -9 | hSpCas9 | negative selection | 2292578 | 56042561 | 56042584 | 12 | - | 24336569 | HL60 | viability | AGAAATGTCCCTGACTGCTGCGG | RPS26 | ENSG00000197728 | -1.9666939133828216 | [470] | [254] | -9 | hSpCas9 | negative selection | 2292579 | 56042581 | 56042604 | 12 | + | 24336569 | HL60 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.323538887827044 | [614] | [259] | -9 | hSpCas9 | negative selection | 2292580 | 56043363 | 56043386 | 12 | - | 24336569 | HL60 | viability | ATACAGCTTGGGAAGCACATAGG | RPS26 | ENSG00000197728 | -1.879505271546871 | [385] | [221] | -9 | hSpCas9 | negative selection | 2292581 | 56043374 | 56043397 | 12 | - | 24336569 | HL60 | viability | TGTAGCTTCACATACAGCTTGGG | RPS26 | ENSG00000197728 | -2.5252988642151752 | [1011] | [371] | -9 | hSpCas9 | negative selection | 2292582 | 56043414 | 56043437 | 12 | + | 24336569 | HL60 | viability | CAATTCACAGCAAAGTAGTCAGG | RPS26 | ENSG00000197728 | -0.6373641357475899 | [343] | [467] | -5 | hSpCas9 | negative selection | 2292583 | 56043439 | 56043462 | 12 | + | 24336569 | HL60 | viability | TCGATCTCGTGAAGCCCGCAAGG | RPS26 | ENSG00000197728 | -0.9520010955306318 | [457] | [500] | -7 | hSpCas9 | negative selection | 2292584 | 56043477 | 56043500 | 12 | - | 24336569 | HL60 | viability | ACTCACCGCAGGTCTAAATCGGG | RPS26 | ENSG00000197728 | 0.7373750216990715 | [285] | [1008] | 6 | hSpCas9 | negative selection | 2292585 | 56044136 | 56044159 | 12 | - | 24336569 | HL60 | viability | CTCCTTACATGGGCTTTGGTGGG | RPS26 | ENSG00000197728 | -0.026555759526506684 | [695] | [1445] | 0 | hSpCas9 | negative selection | 2292586 | 56044146 | 56044169 | 12 | - | 24336569 | HL60 | viability | AAGAACTCAGCTCCTTACATGGG | RPS26 | ENSG00000197728 | -2.2724068833402913 | [604] | [264] | -9 | hSpCas9 | negative selection | 2292587 | 56042463 | 56042486 | 12 | - | 24336569 | KBM7 | viability | GAATAGGCTGCACGTGGCCGCGG | RPS26 | ENSG00000197728 | -0.4330308879797274 | [443] | [896] | -4 | hSpCas9 | negative selection | 2359747 | 56042469 | 56042492 | 12 | - | 24336569 | KBM7 | viability | TGCAGCGAATAGGCTGCACGTGG | RPS26 | ENSG00000197728 | 1.8958286257489316 | [19] | [202] | 9 | hSpCas9 | negative selection | 2359748 | 56042479 | 56042502 | 12 | - | 24336569 | KBM7 | viability | GCACAGTTAGTGCAGCGAATAGG | RPS26 | ENSG00000197728 | 0.3031113716267224 | [815] | [2745] | 2 | hSpCas9 | negative selection | 2359749 | 56042496 | 56042519 | 12 | + | 24336569 | KBM7 | viability | CTGTGCCCGATGCGTGCCCAAGG | RPS26 | ENSG00000197728 | -3.7239104249961343 | [217] | [44] | -9 | hSpCas9 | negative selection | 2359750 | 56042501 | 56042524 | 12 | - | 24336569 | KBM7 | viability | CTTGTCCTTGGGCACGCATCGGG | RPS26 | ENSG00000197728 | -1.2072202286829854 | [683] | [807] | -7 | hSpCas9 | negative selection | 2359751 | 56042512 | 56042535 | 12 | - | 24336569 | KBM7 | viability | TTCTTAATGGCCTTGTCCTTGGG | RPS26 | ENSG00000197728 | -0.1834345982471528 | [865] | [2079] | -1 | hSpCas9 | negative selection | 2359752 | 56042525 | 56042548 | 12 | - | 24336569 | KBM7 | viability | TCGAATGACGAATTTCTTAATGG | RPS26 | ENSG00000197728 | 0.07088789238536691 | [295] | [847] | 0 | hSpCas9 | negative selection | 2359753 | 56042535 | 56042558 | 12 | + | 24336569 | KBM7 | viability | ATTCGTCATTCGAAACATAGTGG | RPS26 | ENSG00000197728 | -0.3857083663112919 | [638] | [1333] | -3 | hSpCas9 | negative selection | 2359754 | 56042552 | 56042575 | 12 | + | 24336569 | KBM7 | viability | TAGTGGAGGCCGCAGCAGTCAGG | RPS26 | ENSG00000197728 | -2.618441317245248 | [384] | [170] | -9 | hSpCas9 | negative selection | 2359755 | 56042561 | 56042584 | 12 | - | 24336569 | KBM7 | viability | AGAAATGTCCCTGACTGCTGCGG | RPS26 | ENSG00000197728 | -8.161824714215005 | [419] | [3] | -9 | hSpCas9 | negative selection | 2359756 | 56042581 | 56042604 | 12 | + | 24336569 | KBM7 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.7823694423732945 | [337] | [133] | -9 | hSpCas9 | negative selection | 2359757 | 56043363 | 56043386 | 12 | - | 24336569 | KBM7 | viability | ATACAGCTTGGGAAGCACATAGG | RPS26 | ENSG00000197728 | -3.184544790715089 | [589] | [176] | -9 | hSpCas9 | negative selection | 2359758 | 56043374 | 56043397 | 12 | - | 24336569 | KBM7 | viability | TGTAGCTTCACATACAGCTTGGG | RPS26 | ENSG00000197728 | -4.65664645350675 | [933] | [100] | -9 | hSpCas9 | negative selection | 2359759 | 56043414 | 56043437 | 12 | + | 24336569 | KBM7 | viability | CAATTCACAGCAAAGTAGTCAGG | RPS26 | ENSG00000197728 | -0.09482597552438143 | [212] | [543] | -1 | hSpCas9 | negative selection | 2359760 | 56043439 | 56043462 | 12 | + | 24336569 | KBM7 | viability | TCGATCTCGTGAAGCCCGCAAGG | RPS26 | ENSG00000197728 | -0.28325690133594617 | [343] | [770] | -2 | hSpCas9 | negative selection | 2359761 | 56043477 | 56043500 | 12 | - | 24336569 | KBM7 | viability | ACTCACCGCAGGTCTAAATCGGG | RPS26 | ENSG00000197728 | 0.7415071381703868 | [240] | [1098] | 6 | hSpCas9 | negative selection | 2359762 | 56044136 | 56044159 | 12 | - | 24336569 | KBM7 | viability | CTCCTTACATGGGCTTTGGTGGG | RPS26 | ENSG00000197728 | 0.3795051959346536 | [331] | [1177] | 3 | hSpCas9 | negative selection | 2359763 | 56044146 | 56044169 | 12 | - | 24336569 | KBM7 | viability | AAGAACTCAGCTCCTTACATGGG | RPS26 | ENSG00000197728 | -1.2664094379389474 | [141] | [160] | -7 | hSpCas9 | negative selection | 2359764 | 56042539 | 56042562 | 12 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CGTCATTCGAAACATAGTGGAGG | RPS26 | ENSG00000197728 | 0.1600579028369996 | [1,1] | [3,0] | 3 | hSpCas9 | positive selection | 3017920 | 56042463 | 56042486 | 12 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GAATAGGCTGCACGTGGCCGCGG | RPS26 | ENSG00000197728 | -0.24222034060753195 | [2,2] | [3,0] | -3 | hSpCas9 | positive selection | 3017921 | 56042479 | 56042502 | 12 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCACAGTTAGTGCAGCGAATAGG | RPS26 | ENSG00000197728 | -0.7944381647219689 | [3,2] | [0,0] | -8 | hSpCas9 | positive selection | 3017922 | 56042447 | 56042470 | 12 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGTCGTGCCAAAAAGGGCCGCGG | RPS26 | ENSG00000197728 | -0.1747885266245034 | [1,1] | [1,0] | -3 | hSpCas9 | positive selection | 3017923 | 56042539 | 56042562 | 12 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CGTCATTCGAAACATAGTGGAGG | RPS26 | ENSG00000197728 | -0.13576147999724075 | [1,1] | [1,0] | -2 | hSpCas9 | positive selection | 3085778 | 56042463 | 56042486 | 12 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GAATAGGCTGCACGTGGCCGCGG | RPS26 | ENSG00000197728 | -1.017992269039047 | [2,2] | [0,0] | -9 | hSpCas9 | positive selection | 3085779 | 56042479 | 56042502 | 12 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCACAGTTAGTGCAGCGAATAGG | RPS26 | ENSG00000197728 | -1.277439261504682 | [3,3] | [0,0] | -9 | hSpCas9 | positive selection | 3085780 | 56042447 | 56042470 | 12 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGTCGTGCCAAAAAGGGCCGCGG | RPS26 | ENSG00000197728 | -0.2975517623487274 | [1,1] | [0,0] | -4 | hSpCas9 | positive selection | 3085781 | 56043478 | 56043501 | | - | 24336571 | A375 | resistance to PLX after 7 days | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.30228419775164644 | [5,7] | [11,6] | 8 | hSpCas9 | positive selection | 3141847 | 56042581 | 56042604 | | + | 24336571 | A375 | resistance to PLX after 7 days | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | 0.211741381505268 | [3,3] | [3,4] | 6 | hSpCas9 | positive selection | 3141848 | 56043478 | 56043501 | | - | 24336571 | A375 | resistance to PLX after 14 days | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.8632553172567864 | [9,5] | [5,7] | 7 | hSpCas9 | positive selection | 3199640 | 56042581 | 56042604 | | + | 24336571 | A375 | resistance to PLX after 14 days | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | 0.5494798276095144 | [4,3] | [3,1] | 5 | hSpCas9 | positive selection | 3199641 | 56043478 | 56043501 | | - | 24336571 | A375 | viability after 7 days | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -1.024395695208971 | [15] | [5,7] | -9 | hSpCas9 | negative selection | 3257433 | 56042581 | 56042604 | | + | 24336571 | A375 | viability after 7 days | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.205857719797253 | [9] | [3,3] | -9 | hSpCas9 | negative selection | 3257434 | 56043478 | 56043501 | | - | 24336571 | A375 | viability after 14 days | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.8737875463363105 | [15] | [9,5] | -8 | hSpCas9 | negative selection | 3315226 | 56042581 | 56042604 | | + | 24336571 | A375 | viability after 14 days | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.029375417957661 | [9] | [4,3] | -8 | hSpCas9 | negative selection | 3315227 | 56043414 | 56043437 | 12 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CAATTCACAGCAAAGTAGTCAGG | RPS26 | ENSG00000197728 | 1.1280431945008687 | [69,69] | [0,0] | 5 | hSpCas9 | positive selection | 3390626 | 56044140 | 56044163 | 12 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TCAGCTCCTTACATGGGCTTTGG | RPS26 | ENSG00000197728 | 0.47596649792117546 | [109,109] | [0,0] | 2 | hSpCas9 | positive selection | 3390627 | 56044134 | 56044157 | 12 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | 2.1280431945008687 | [34,34] | [0,0] | 7 | hSpCas9 | positive selection | 3390628 | 56042538 | 56042561 | 12 | + | 26780180 | HT29 | viability (Avana library 4 designs) | CGTCATTCGAAACATAGTGGAGG | RPS26 | ENSG00000197728 | 5.04728359018224 | [] | [] | 9 | hSpCas9 | negative selection | 3456301 | 56042463 | 56042486 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GAATAGGCTGCACGTGGCCGCGG | RPS26 | ENSG00000197728 | 1.23911402264687 | [] | [] | 5 | hSpCas9 | negative selection | 3456302 | 56042479 | 56042502 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GCACAGTTAGTGCAGCGAATAGG | RPS26 | ENSG00000197728 | 4.21783509973899 | [] | [] | 9 | hSpCas9 | negative selection | 3456303 | 56042446 | 56042469 | 12 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GGTCGTGCCAAAAAGGGCCGCGG | RPS26 | ENSG00000197728 | 6.61526592981492 | [] | [] | 9 | hSpCas9 | negative selection | 3456304 | 56042446 | 56042469 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGTCGTGCCAAAAAGGGCCGCGG | RPS26 | ENSG00000197728 | -13.3228999080797 | [] | [] | -8 | hSpCas9 | negative selection | 3554710 | 56042479 | 56042502 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCACAGTTAGTGCAGCGAATAGG | RPS26 | ENSG00000197728 | -0.141000694982292 | [] | [] | 0 | hSpCas9 | negative selection | 3554711 | 56042538 | 56042561 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CGTCATTCGAAACATAGTGGAGG | RPS26 | ENSG00000197728 | -15.9344784524404 | [] | [] | -9 | hSpCas9 | negative selection | 3554712 | 56042463 | 56042486 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GAATAGGCTGCACGTGGCCGCGG | RPS26 | ENSG00000197728 | 2.02779498556973 | [] | [] | 3 | hSpCas9 | negative selection | 3554713 | 56042561 | 56042584 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AGAAATGTCCCTGACTGCTGCGG | RPS26 | ENSG00000197728 | -12.4395108017743 | [] | [] | -8 | hSpCas9 | negative selection | 3554714 | 56042502 | 56042525 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCTTGTCCTTGGGCACGCATCGG | RPS26 | ENSG00000197728 | -11.7121962000993 | [] | [] | -8 | hSpCas9 | negative selection | 3554715 | 56042446 | 56042469 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | GGTCGTGCCAAAAAGGGCCGCGG | RPS26 | ENSG00000197728 | 27.0248428516208 | [] | [] | 9 | hSpCas9 | negative selection | 3663369 | 56042479 | 56042502 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | GCACAGTTAGTGCAGCGAATAGG | RPS26 | ENSG00000197728 | 13.2126247602925 | [] | [] | 7 | hSpCas9 | negative selection | 3663370 | 56042538 | 56042561 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | CGTCATTCGAAACATAGTGGAGG | RPS26 | ENSG00000197728 | 34.3836374842392 | [] | [] | 9 | hSpCas9 | negative selection | 3663371 | 56042463 | 56042486 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | GAATAGGCTGCACGTGGCCGCGG | RPS26 | ENSG00000197728 | 1.28335140325112 | [] | [] | 1 | hSpCas9 | negative selection | 3663372 | 56042561 | 56042584 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | AGAAATGTCCCTGACTGCTGCGG | RPS26 | ENSG00000197728 | 24.818542274841 | [] | [] | 9 | hSpCas9 | negative selection | 3663373 | 56042502 | 56042525 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | CCTTGTCCTTGGGCACGCATCGG | RPS26 | ENSG00000197728 | 18.947557460532 | [] | [] | 8 | hSpCas9 | negative selection | 3663374 | 56042446 | 56042469 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGTCGTGCCAAAAAGGGCCGCGG | RPS26 | ENSG00000197728 | -0.4073704758696235 | [5] | [3,3] | -6 | hSpCas9 | positive selection | 3771976 | 56042479 | 56042502 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCACAGTTAGTGCAGCGAATAGG | RPS26 | ENSG00000197728 | -0.2418591109131305 | [4] | [4,2] | -4 | hSpCas9 | positive selection | 3771977 | 56042538 | 56042561 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CGTCATTCGAAACATAGTGGAGG | RPS26 | ENSG00000197728 | -1.9813559028137986 | [4] | [0,0] | -9 | hSpCas9 | positive selection | 3771978 | 56042463 | 56042486 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GAATAGGCTGCACGTGGCCGCGG | RPS26 | ENSG00000197728 | 0.4902617050627984 | [3] | [5,5] | 9 | hSpCas9 | positive selection | 3771979 | 56042561 | 56042584 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AGAAATGTCCCTGACTGCTGCGG | RPS26 | ENSG00000197728 | -0.6411544112901819 | [6] | [4,2] | -7 | hSpCas9 | positive selection | 3771980 | 56042502 | 56042525 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCTTGTCCTTGGGCACGCATCGG | RPS26 | ENSG00000197728 | -1.0471463963522036 | [5] | [2,1] | -9 | hSpCas9 | positive selection | 3771981 | 56042446 | 56042469 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGTCGTGCCAAAAAGGGCCGCGG | RPS26 | ENSG00000197728 | -1.007232655831007 | [5] | [0,3] | -8 | hSpCas9 | positive selection | 3880583 | 56042479 | 56042502 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCACAGTTAGTGCAGCGAATAGG | RPS26 | ENSG00000197728 | -1.179924919092563 | [5] | [2,0] | -9 | hSpCas9 | positive selection | 3880584 | 56042538 | 56042561 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CGTCATTCGAAACATAGTGGAGG | RPS26 | ENSG00000197728 | -0.6816872481557358 | [5] | [3,1] | -7 | hSpCas9 | positive selection | 3880585 | 56042463 | 56042486 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GAATAGGCTGCACGTGGCCGCGG | RPS26 | ENSG00000197728 | -0.1173851425753962 | [4] | [4,2] | -2 | hSpCas9 | positive selection | 3880586 | 56042561 | 56042584 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AGAAATGTCCCTGACTGCTGCGG | RPS26 | ENSG00000197728 | -1.0457145321700572 | [6] | [1,2] | -8 | hSpCas9 | positive selection | 3880587 | 56042502 | 56042525 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCTTGTCCTTGGGCACGCATCGG | RPS26 | ENSG00000197728 | -1.5448383089792221 | [5] | [2,0] | -9 | hSpCas9 | positive selection | 3880588 | 56044134 | 56044157 | 12 | + | 26780180 | A375 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | 2.52778144659238 | [] | [] | 9 | hSpCas9 | negative selection | 3990623 | 56043478 | 56043501 | 12 | - | 26780180 | A375 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.677123319851133 | [] | [] | 2 | hSpCas9 | negative selection | 3990624 | 56042581 | 56042604 | 12 | + | 26780180 | A375 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | 1.68398249548437 | [] | [] | 9 | hSpCas9 | negative selection | 3990625 | 56042417 | 56042440 | 12 | + | 26780180 | A375 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | 1.33065823314002 | [] | [] | 7 | hSpCas9 | negative selection | 3990626 | 56044134 | 56044157 | 12 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | 3.01417413546498 | [] | [] | 9 | hSpCas9 | negative selection | 4098589 | 56043478 | 56043501 | 12 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.326742889214138 | [] | [] | 0 | hSpCas9 | negative selection | 4098590 | 56042581 | 56042604 | 12 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | 2.41229340472098 | [] | [] | 9 | hSpCas9 | negative selection | 4098591 | 56042417 | 56042440 | 12 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | 2.21081252081206 | [] | [] | 9 | hSpCas9 | negative selection | 4098592 | 56043478 | 56043501 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.20532351460123732 | [2] | [1,2] | 5 | hSpCas9 | positive selection | 4167533 | 56042581 | 56042604 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -0.2956378727431532 | [2] | [0,1] | -6 | hSpCas9 | positive selection | 4167534 | 56043478 | 56043501 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.07226387840881748 | [2] | [0,3,1,0] | 0 | hSpCas9 | positive selection | 4231555 | 56042581 | 56042604 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -0.6441031360185816 | [2] | [0,0,0,0] | -8 | hSpCas9 | positive selection | 4231556 | 56042581 | 56042604 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.2110033090034524 | [2] | [0,0] | -9 | hSpCas9 | positive selection | 4295750 | 56043478 | 56043501 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.07552426644304 | [1] | [1,1] | 1 | hSpCas9 | positive selection | 4295751 | 56042417 | 56042440 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -0.8209085279943112 | [2] | [0,0] | -9 | hSpCas9 | positive selection | 4295752 | 56044134 | 56044157 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -0.6928646542405992 | [3] | [1,1] | -9 | hSpCas9 | positive selection | 4360005 | 56042097 | 56042120 | 12 | + | 27661255 | K562 | viability | GTAGGGATCTCATGCTATATAGG | RPS26 | ENSG00000197728 | -1.3423480423283585 | [1552,1502] | [499,465] | -9 | dCas9-KRAB | negative selection | 5508573 | 56041927 | 56041950 | 12 | - | 27661255 | K562 | viability | GGGACTATTTAGCCGGATGGCGG | RPS26 | ENSG00000197728 | -0.003382053920693129 | [1054,863] | [822,719] | 0 | dCas9-KRAB | negative selection | 5508574 | 56042581 | 56042604 | 12 | + | 27260156 | BXPC3 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.3329334523722427 | [225] | [74,91,108,101] | -9 | hSpCas9 | negative selection | 5568210 | 56043478 | 56043501 | 12 | - | 27260156 | BXPC3 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.4018803647612168 | [173] | [161,264,250,295] | 8 | hSpCas9 | negative selection | 5568211 | 56042417 | 56042440 | 12 | + | 27260156 | BXPC3 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -1.1160132107402247 | [208] | [116,129,75,71] | -9 | hSpCas9 | negative selection | 5568212 | 56044134 | 56044157 | 12 | + | 27260156 | BXPC3 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.5944108069630945 | [784] | [204,335,282,263] | -9 | hSpCas9 | negative selection | 5632465 | 56042581 | 56042604 | 12 | + | 27260156 | A673 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -0.8003902655009731 | [225] | [151,141,124,206] | -9 | hSpCas9 | negative selection | 5689461 | 56043478 | 56043501 | 12 | - | 27260156 | A673 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.13841591277904208 | [173] | [245,179,254,241] | 3 | hSpCas9 | negative selection | 5689462 | 56042417 | 56042440 | 12 | + | 27260156 | A673 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -0.631986465038868 | [208] | [186,113,163,187] | -9 | hSpCas9 | negative selection | 5689463 | 56044134 | 56044157 | 12 | + | 27260156 | A673 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.3377420393151493 | [784] | [472,404,247,376] | -9 | hSpCas9 | negative selection | 5753716 | 56042581 | 56042604 | 12 | + | 27260156 | A375 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.186283039790408 | [225] | [38,112,35,51] | -9 | hSpCas9 | negative selection | 5810712 | 56043478 | 56043501 | 12 | - | 27260156 | A375 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.08349401506436505 | [173] | [180,220,227,145] | -1 | hSpCas9 | negative selection | 5810713 | 56042417 | 56042440 | 12 | + | 27260156 | A375 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -1.5137220100367055 | [208] | [173,52,82,33] | -9 | hSpCas9 | negative selection | 5810714 | 56044134 | 56044157 | 12 | + | 27260156 | A375 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.5355183463811217 | [784] | [195,75,210,139] | -9 | hSpCas9 | negative selection | 5874967 | 56042581 | 56042604 | 12 | + | 27260156 | COLO741 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.635097130858114 | [225] | [93,80,102] | -9 | hSpCas9 | negative selection | 5931963 | 56043478 | 56043501 | 12 | - | 27260156 | COLO741 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.05022842460383359 | [173] | [232,208,203] | -1 | hSpCas9 | negative selection | 5931964 | 56042417 | 56042440 | 12 | + | 27260156 | COLO741 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -0.8003970467668573 | [208] | [147,140,168] | -9 | hSpCas9 | negative selection | 5931965 | 56044134 | 56044157 | 12 | + | 27260156 | COLO741 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.6136879394392871 | [784] | [387,292,307] | -9 | hSpCas9 | negative selection | 5996218 | 56042581 | 56042604 | 12 | + | 27260156 | CAL120 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.991000940307652 | [225] | [48,14,43] | -9 | hSpCas9 | negative selection | 6053214 | 56043478 | 56043501 | 12 | - | 27260156 | CAL120 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.3636926415435253 | [173] | [415,252,188] | 5 | hSpCas9 | negative selection | 6053215 | 56042417 | 56042440 | 12 | + | 27260156 | CAL120 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -2.455410202255325 | [208] | [97,12,38] | -9 | hSpCas9 | negative selection | 6053216 | 56044134 | 56044157 | 12 | + | 27260156 | CAL120 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.2874874622008 | [784] | [277,194,139] | -9 | hSpCas9 | negative selection | 6117469 | 56042581 | 56042604 | 12 | + | 27260156 | CADOES1 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.7802661867124099 | [225] | [27,79,72,63] | -9 | hSpCas9 | negative selection | 6174465 | 56043478 | 56043501 | 12 | - | 27260156 | CADOES1 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.00010574666669826982 | [173] | [161,245,114,122] | 0 | hSpCas9 | negative selection | 6174466 | 56042417 | 56042440 | 12 | + | 27260156 | CADOES1 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -1.5567291256152063 | [208] | [61,63,28,110] | -9 | hSpCas9 | negative selection | 6174467 | 56044134 | 56044157 | 12 | + | 27260156 | CADOES1 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.7519927801656763 | [784] | [217,205,200,242] | -9 | hSpCas9 | negative selection | 6238720 | 56042581 | 56042604 | 12 | + | 27260156 | EWS502 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.2631213527303595 | [225] | [32,52,39,76] | -9 | hSpCas9 | negative selection | 6295716 | 56043478 | 56043501 | 12 | - | 27260156 | EWS502 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.5948118406542264 | [173] | [209,282,339,288] | 8 | hSpCas9 | negative selection | 6295717 | 56042417 | 56042440 | 12 | + | 27260156 | EWS502 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -3.0595611700685685 | [208] | [30,18,43,10] | -9 | hSpCas9 | negative selection | 6295718 | 56044134 | 56044157 | 12 | + | 27260156 | EWS502 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.6769858595563827 | [784] | [203,131,111,56] | -9 | hSpCas9 | negative selection | 6359971 | 56042581 | 56042604 | 12 | + | 27260156 | EW8 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.4471412676760431 | [225] | [105,79,30,61] | -9 | hSpCas9 | negative selection | 6416967 | 56043478 | 56043501 | 12 | - | 27260156 | EW8 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.38064357050244113 | [173] | [123,310,141,157] | 7 | hSpCas9 | negative selection | 6416968 | 56042417 | 56042440 | 12 | + | 27260156 | EW8 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -1.0188805007673307 | [208] | [174,58,24,94] | -9 | hSpCas9 | negative selection | 6416969 | 56044134 | 56044157 | 12 | + | 27260156 | EW8 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.6849089345722592 | [784] | [185,259,215,124] | -9 | hSpCas9 | negative selection | 6481222 | 56042581 | 56042604 | 12 | + | 27260156 | CORL105 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.8404262748722904 | [225] | [66,50,88,90] | -9 | hSpCas9 | negative selection | 6538218 | 56043478 | 56043501 | 12 | - | 27260156 | CORL105 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.07083780891930691 | [173] | [142,137,308,202] | -1 | hSpCas9 | negative selection | 6538219 | 56042417 | 56042440 | 12 | + | 27260156 | CORL105 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -2.7240459572594125 | [208] | [39,58,18,26] | -9 | hSpCas9 | negative selection | 6538220 | 56044134 | 56044157 | 12 | + | 27260156 | CORL105 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.4761691684281326 | [784] | [363,281,453,242] | -9 | hSpCas9 | negative selection | 6602473 | 56042581 | 56042604 | 12 | + | 27260156 | HS294T | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.10865351390395 | [225] | [12,4,39,24] | -9 | hSpCas9 | negative selection | 6659469 | 56043478 | 56043501 | 12 | - | 27260156 | HS294T | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.13567773783640447 | [173] | [50,53,65,137] | 1 | hSpCas9 | negative selection | 6659470 | 56042417 | 56042440 | 12 | + | 27260156 | HS294T | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -2.242205314995833 | [208] | [1,8,31,28] | -9 | hSpCas9 | negative selection | 6659471 | 56044134 | 56044157 | 12 | + | 27260156 | HS294T | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.115328253057511 | [784] | [35,24,107,124] | -9 | hSpCas9 | negative selection | 6723724 | 56042581 | 56042604 | 12 | + | 27260156 | HCC44 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.095549936709582 | [225] | [39,0,71,131] | -9 | hSpCas9 | negative selection | 6780720 | 56043478 | 56043501 | 12 | - | 27260156 | HCC44 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.8658490068640303 | [173] | [175,467,227,499] | 9 | hSpCas9 | negative selection | 6780721 | 56042417 | 56042440 | 12 | + | 27260156 | HCC44 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -4.329711177490908 | [208] | [24,1,23,0] | -9 | hSpCas9 | negative selection | 6780722 | 56044134 | 56044157 | 12 | + | 27260156 | HCC44 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.6260911363638155 | [784] | [208,143,133,92] | -9 | hSpCas9 | negative selection | 6844975 | 56042581 | 56042604 | 12 | + | 27260156 | G402 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -3.092788099781597 | [225] | [0,29,7,82] | -9 | hSpCas9 | negative selection | 6901971 | 56043478 | 56043501 | 12 | - | 27260156 | G402 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -1.2672292686195155 | [173] | [117,54,138,44] | -8 | hSpCas9 | negative selection | 6901972 | 56042417 | 56042440 | 12 | + | 27260156 | G402 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -2.6317930108652803 | [208] | [29,65,63,5] | -9 | hSpCas9 | negative selection | 6901973 | 56044134 | 56044157 | 12 | + | 27260156 | G402 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -3.047715710834469 | [784] | [122,117,105,116] | -9 | hSpCas9 | negative selection | 6966226 | 56042581 | 56042604 | 12 | + | 27260156 | L33 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.1648130473002045 | [225] | [153,19,67,90] | -9 | hSpCas9 | negative selection | 7023222 | 56043478 | 56043501 | 12 | - | 27260156 | L33 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.07254555784766104 | [173] | [158,86,88,218] | 1 | hSpCas9 | negative selection | 7023223 | 56042417 | 56042440 | 12 | + | 27260156 | L33 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -0.9491190188530829 | [208] | [131,55,53,77] | -9 | hSpCas9 | negative selection | 7023224 | 56044134 | 56044157 | 12 | + | 27260156 | L33 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -0.9150564889148507 | [784] | [375,178,265,429] | -9 | hSpCas9 | negative selection | 7087477 | 56042581 | 56042604 | 12 | + | 27260156 | K562 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -3.100261204058545 | [225] | [29,55,7,3] | -9 | hSpCas9 | negative selection | 7144473 | 56043478 | 56043501 | 12 | - | 27260156 | K562 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.2614958277466468 | [173] | [88,80,172,161] | -3 | hSpCas9 | negative selection | 7144474 | 56042417 | 56042440 | 12 | + | 27260156 | K562 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -4.897025914215388 | [208] | [5,2,2,11] | -9 | hSpCas9 | negative selection | 7144475 | 56044134 | 56044157 | 12 | + | 27260156 | K562 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.8688640680337165 | [784] | [72,134,307,228] | -9 | hSpCas9 | negative selection | 7208728 | 56042581 | 56042604 | 12 | + | 27260156 | HT29 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.5916366616615854 | [225] | [100,25,15,41] | -9 | hSpCas9 | negative selection | 7265724 | 56043478 | 56043501 | 12 | - | 27260156 | HT29 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.5415997379377936 | [173] | [449,239,295,254] | 9 | hSpCas9 | negative selection | 7265725 | 56042417 | 56042440 | 12 | + | 27260156 | HT29 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -2.5232190153458705 | [208] | [75,2,12,78] | -9 | hSpCas9 | negative selection | 7265726 | 56044134 | 56044157 | 12 | + | 27260156 | HT29 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.6971588150682058 | [784] | [104,188,165,129] | -9 | hSpCas9 | negative selection | 7329979 | 56042581 | 56042604 | 12 | + | 27260156 | MHHES1 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.3316232668157297 | [225] | [79,196,81,59] | -9 | hSpCas9 | negative selection | 7386975 | 56043478 | 56043501 | 12 | - | 27260156 | MHHES1 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.6323595720746668 | [173] | [508,232,346,168] | 9 | hSpCas9 | negative selection | 7386976 | 56042417 | 56042440 | 12 | + | 27260156 | MHHES1 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -1.375142311484738 | [208] | [196,21,124,35] | -9 | hSpCas9 | negative selection | 7386977 | 56044134 | 56044157 | 12 | + | 27260156 | MHHES1 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.8215410263312293 | [784] | [207,239,417,147] | -9 | hSpCas9 | negative selection | 7451230 | 56042581 | 56042604 | 12 | + | 27260156 | MEWO | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.656412808133931 | [225] | [60,72,65] | -9 | hSpCas9 | negative selection | 7508226 | 56043478 | 56043501 | 12 | - | 27260156 | MEWO | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.161342653809756 | [173] | [289,71,102] | -4 | hSpCas9 | negative selection | 7508227 | 56042417 | 56042440 | 12 | + | 27260156 | MEWO | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -0.44615337732150095 | [208] | [150,138,141] | -7 | hSpCas9 | negative selection | 7508228 | 56044134 | 56044157 | 12 | + | 27260156 | MEWO | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.3187034426881312 | [784] | [338,261,290] | -9 | hSpCas9 | negative selection | 7572481 | 56042581 | 56042604 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.99273148071132 | [225] | [47,49,31,72] | -9 | hSpCas9 | negative selection | 7629477 | 56043478 | 56043501 | 12 | - | 27260156 | LNCAPCLONEFGC | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.064194376769098 | [173] | [107,149,151,193] | -1 | hSpCas9 | negative selection | 7629478 | 56042417 | 56042440 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -1.482048380374566 | [208] | [83,46,93,50] | -9 | hSpCas9 | negative selection | 7629479 | 56044134 | 56044157 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.9991926171675078 | [784] | [212,159,171,165] | -9 | hSpCas9 | negative selection | 7693732 | 56042581 | 56042604 | 12 | + | 27260156 | PANC0327 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.5038417034553486 | [225] | [15,65,18,34] | -9 | hSpCas9 | negative selection | 7750728 | 56043478 | 56043501 | 12 | - | 27260156 | PANC0327 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.5505284869895275 | [173] | [151,73,111,91] | -7 | hSpCas9 | negative selection | 7750729 | 56042417 | 56042440 | 12 | + | 27260156 | PANC0327 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -3.3385222479541126 | [208] | [42,5,5,21] | -9 | hSpCas9 | negative selection | 7750730 | 56044134 | 56044157 | 12 | + | 27260156 | PANC0327 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.222038857458508 | [784] | [30,148,115,291] | -9 | hSpCas9 | negative selection | 7814983 | 56042581 | 56042604 | 12 | + | 27260156 | NCIH2009 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -3.006504799338364 | [225] | [74,31,17] | -9 | hSpCas9 | negative selection | 7871979 | 56043478 | 56043501 | 12 | - | 27260156 | NCIH2009 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.6331370116073223 | [173] | [181,154,137] | -7 | hSpCas9 | negative selection | 7871980 | 56042417 | 56042440 | 12 | + | 27260156 | NCIH2009 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -5.234016385773452 | [208] | [6,13,1] | -9 | hSpCas9 | negative selection | 7871981 | 56044134 | 56044157 | 12 | + | 27260156 | NCIH2009 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.6889823981432563 | [784] | [150,289,62] | -9 | hSpCas9 | negative selection | 7936234 | 56042581 | 56042604 | 12 | + | 27260156 | NCIH1373 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -0.8708695177170185 | [225] | [129,30,52,95] | -7 | hSpCas9 | negative selection | 7993230 | 56043478 | 56043501 | 12 | - | 27260156 | NCIH1373 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.05116189962637252 | [173] | [229,234,278,13] | 0 | hSpCas9 | negative selection | 7993231 | 56042417 | 56042440 | 12 | + | 27260156 | NCIH1373 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -2.5786424366757705 | [208] | [50,4,70,8] | -9 | hSpCas9 | negative selection | 7993232 | 56044134 | 56044157 | 12 | + | 27260156 | NCIH1373 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.468076276305009 | [784] | [355,114,31,44] | -9 | hSpCas9 | negative selection | 8057485 | 56042581 | 56042604 | 12 | + | 27260156 | PATU8902 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -6.0450766571207435 | [225] | [1,1,1,14] | -9 | hSpCas9 | negative selection | 8114481 | 56043478 | 56043501 | 12 | - | 27260156 | PATU8902 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.521804738419662 | [173] | [231,98,129,228] | -5 | hSpCas9 | negative selection | 8114482 | 56042417 | 56042440 | 12 | + | 27260156 | PATU8902 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -7.64018721509635 | [208] | [1,0,0,1] | -9 | hSpCas9 | negative selection | 8114483 | 56044134 | 56044157 | 12 | + | 27260156 | PATU8902 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -3.5066480640449322 | [784] | [18,157,147,39] | -9 | hSpCas9 | negative selection | 8178736 | 56042581 | 56042604 | 12 | + | 27260156 | PANC1 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.098306738092232 | [225] | [65,61,47,12] | -9 | hSpCas9 | negative selection | 8235732 | 56043478 | 56043501 | 12 | - | 27260156 | PANC1 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.3577913439109277 | [173] | [156,292,214,129] | 6 | hSpCas9 | negative selection | 8235733 | 56042417 | 56042440 | 12 | + | 27260156 | PANC1 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -3.407258171808585 | [208] | [26,10,4,21] | -9 | hSpCas9 | negative selection | 8235734 | 56044134 | 56044157 | 12 | + | 27260156 | PANC1 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.6255001216268106 | [784] | [90,66,104,155] | -9 | hSpCas9 | negative selection | 8299987 | 56042581 | 56042604 | 12 | + | 27260156 | PANC0813 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.3687264120011573 | [225] | [35,38,73,54] | -9 | hSpCas9 | negative selection | 8356983 | 56043478 | 56043501 | 12 | - | 27260156 | PANC0813 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 1.0181703012449117 | [173] | [119,1165,128,221] | 9 | hSpCas9 | negative selection | 8356984 | 56042417 | 56042440 | 12 | + | 27260156 | PANC0813 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -3.6043335657002418 | [208] | [27,5,1,43] | -9 | hSpCas9 | negative selection | 8356985 | 56044134 | 56044157 | 12 | + | 27260156 | PANC0813 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.9757388171091137 | [784] | [276,149,304,210] | -9 | hSpCas9 | negative selection | 8421238 | 56042581 | 56042604 | 12 | + | 27260156 | RDES | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.8459347878025054 | [225] | [45,95,80,66] | -9 | hSpCas9 | negative selection | 8478234 | 56043478 | 56043501 | 12 | - | 27260156 | RDES | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.3891620190647125 | [173] | [188,287,293,287] | 6 | hSpCas9 | negative selection | 8478235 | 56042417 | 56042440 | 12 | + | 27260156 | RDES | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -1.5586752775146537 | [208] | [77,62,112,71] | -9 | hSpCas9 | negative selection | 8478236 | 56044134 | 56044157 | 12 | + | 27260156 | RDES | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.070486540256666 | [784] | [192,149,197,341] | -9 | hSpCas9 | negative selection | 8542489 | 56042581 | 56042604 | 12 | + | 27260156 | PC3 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -0.5939207982234942 | [225] | [50,59,298,291] | -8 | hSpCas9 | negative selection | 8599485 | 56043478 | 56043501 | 12 | - | 27260156 | PC3 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.444808422238262 | [173] | [94,224,708,142] | 8 | hSpCas9 | negative selection | 8599486 | 56042417 | 56042440 | 12 | + | 27260156 | PC3 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -0.3647146074182943 | [208] | [142,103,333,121] | -7 | hSpCas9 | negative selection | 8599487 | 56044134 | 56044157 | 12 | + | 27260156 | PC3 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.0314685050572872 | [784] | [295,336,513,432] | -9 | hSpCas9 | negative selection | 8663740 | 56042581 | 56042604 | 12 | + | 27260156 | PATU8988T | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.2742371879157526 | [225] | [4,9,118,41] | -9 | hSpCas9 | negative selection | 8720736 | 56043478 | 56043501 | 12 | - | 27260156 | PATU8988T | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.8884564853913554 | [173] | [147,224,632,218] | 9 | hSpCas9 | negative selection | 8720737 | 56042417 | 56042440 | 12 | + | 27260156 | PATU8988T | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -1.6465032056723146 | [208] | [48,86,41,83] | -9 | hSpCas9 | negative selection | 8720738 | 56044134 | 56044157 | 12 | + | 27260156 | PATU8988T | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.4219202079414432 | [784] | [177,360,347,248] | -9 | hSpCas9 | negative selection | 8784991 | 56042581 | 56042604 | 12 | + | 27260156 | T47D | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.8240768217068657 | [225] | [90,70,60,74] | -9 | hSpCas9 | negative selection | 8841987 | 56043478 | 56043501 | 12 | - | 27260156 | T47D | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.4250237181550782 | [173] | [254,303,273,251] | 8 | hSpCas9 | negative selection | 8841988 | 56042417 | 56042440 | 12 | + | 27260156 | T47D | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -1.1720860314731072 | [208] | [124,108,78,119] | -9 | hSpCas9 | negative selection | 8841989 | 56044134 | 56044157 | 12 | + | 27260156 | T47D | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.6754447416597893 | [784] | [280,261,311,291] | -9 | hSpCas9 | negative selection | 8906242 | 56042581 | 56042604 | 12 | + | 27260156 | SU8686 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -2.7052817603005863 | [225] | [13,29,73,20] | -9 | hSpCas9 | negative selection | 8963238 | 56043478 | 56043501 | 12 | - | 27260156 | SU8686 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.5759462007206073 | [173] | [250,216,215,364] | 8 | hSpCas9 | negative selection | 8963239 | 56042417 | 56042440 | 12 | + | 27260156 | SU8686 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -3.148458400080391 | [208] | [29,31,4,23] | -9 | hSpCas9 | negative selection | 8963240 | 56044134 | 56044157 | 12 | + | 27260156 | SU8686 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -2.175035132699867 | [784] | [178,165,108,243] | -9 | hSpCas9 | negative selection | 9027493 | 56042581 | 56042604 | 12 | + | 27260156 | SKES1 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.24696415611664 | [225] | [82,206,69,37] | -9 | hSpCas9 | negative selection | 9084489 | 56043478 | 56043501 | 12 | - | 27260156 | SKES1 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.04657997889818244 | [173] | [126,188,206,184] | 1 | hSpCas9 | negative selection | 9084490 | 56042417 | 56042440 | 12 | + | 27260156 | SKES1 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -0.5047014731909605 | [208] | [159,251,52,137] | -8 | hSpCas9 | negative selection | 9084491 | 56044134 | 56044157 | 12 | + | 27260156 | SKES1 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.623877568126098 | [784] | [295,287,202,238] | -9 | hSpCas9 | negative selection | 9148744 | 56042581 | 56042604 | 12 | + | 27260156 | TOV112D | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.4104455689900146 | [225] | [130,79,80,51] | -9 | hSpCas9 | negative selection | 9205740 | 56043478 | 56043501 | 12 | - | 27260156 | TOV112D | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | 0.22525964340312754 | [173] | [175,141,165,309] | 4 | hSpCas9 | negative selection | 9205741 | 56042417 | 56042440 | 12 | + | 27260156 | TOV112D | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -0.845998916555956 | [208] | [178,77,108,95] | -9 | hSpCas9 | negative selection | 9205742 | 56044134 | 56044157 | 12 | + | 27260156 | TOV112D | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.0859799041671758 | [784] | [465,624,250,213] | -9 | hSpCas9 | negative selection | 9269995 | 56042581 | 56042604 | 12 | + | 27260156 | TC71 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -0.7517467009703944 | [225] | [141,61,153,221] | -9 | hSpCas9 | negative selection | 9326991 | 56043478 | 56043501 | 12 | - | 27260156 | TC71 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.013907670442907971 | [173] | [204,246,134,150] | 0 | hSpCas9 | negative selection | 9326992 | 56042417 | 56042440 | 12 | + | 27260156 | TC71 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -0.4384925266536235 | [208] | [173,201,165,115] | -8 | hSpCas9 | negative selection | 9326993 | 56044134 | 56044157 | 12 | + | 27260156 | TC71 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.1355466945456951 | [784] | [329,411,430,356] | -9 | hSpCas9 | negative selection | 9391246 | 56042581 | 56042604 | 12 | + | 27260156 | TC32 | viability | TCTGAAGCGAGCGTCTTCGATGG | RPS26 | ENSG00000197728 | -1.0787605140741443 | [225] | [108,50,184,82] | -9 | hSpCas9 | negative selection | 9448242 | 56043478 | 56043501 | 12 | - | 27260156 | TC32 | viability | TACTCACCGCAGGTCTAAATCGG | RPS26 | ENSG00000197728 | -0.5721173681164755 | [173] | [104,66,180,109] | -8 | hSpCas9 | negative selection | 9448243 | 56042417 | 56042440 | 12 | + | 27260156 | TC32 | viability | TGTCGCAGACAAAGAAAAGAAGG | RPS26 | ENSG00000197728 | -0.9710259116386284 | [208] | [118,55,113,123] | -9 | hSpCas9 | negative selection | 9448244 | 56044134 | 56044157 | 12 | + | 27260156 | TC32 | viability | CCCCCACCAAAGCCCATGTAAGG | RPS26 | ENSG00000197728 | -1.5582997141314696 | [784] | [211,55,409,428] | -9 | hSpCas9 | negative selection | 9512497 |