Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:8698
• Symbol:S1PR4
• Description:sphingosine-1-phosphate receptor 4

DataSource: http://genomecrispr.dkfz.de/#!/results/S1PR4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
3179181	3179204	19	-	26472758	Jiyoye	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	1.9921378822270288	[0]	[2]	8	hSpCas9	negative selection	141784
3179568	3179591	19	-	26472758	Jiyoye	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	-1.1616674538520058	[88]	[29]	-7	hSpCas9	negative selection	141785
3178785	3178808	19	+	26472758	Jiyoye	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.3273746702927539	[222]	[210]	2	hSpCas9	negative selection	141786
3178822	3178845	19	+	26472758	Jiyoye	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	0.7373239831982044	[279]	[351]	5	hSpCas9	negative selection	141787
3178978	3179001	19	+	26472758	Jiyoye	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	0.8911602345022085	[142]	[199]	6	hSpCas9	negative selection	141788
3179365	3179388	19	-	26472758	Jiyoye	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-2.499715214102645	[14]	[1]	-9	hSpCas9	negative selection	141789
3179530	3179553	19	-	26472758	Jiyoye	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.6386283081072515	[63]	[30]	-4	hSpCas9	negative selection	141790
3179755	3179778	19	-	26472758	Jiyoye	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	-1.0360590096036224	[154]	[56]	-6	hSpCas9	negative selection	141791
3179330	3179353	19	-	26472758	Jiyoye	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	-0.9431059094307286	[333]	[130]	-6	hSpCas9	negative selection	141792
3179494	3179517	19	+	26472758	Jiyoye	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	0.49896785742536387	[136]	[145]	4	hSpCas9	negative selection	141793
3179181	3179204	19	-	26472758	KBM7	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-3.776534237000844	[122,178]	[8,1]	-9	hSpCas9	negative selection	332902
3179568	3179591	19	-	26472758	KBM7	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	-0.4670604057557186	[337,178]	[64,103]	-4	hSpCas9	negative selection	332903
3178785	3178808	19	+	26472758	KBM7	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.5527939122117383	[799,635]	[607,387]	6	hSpCas9	negative selection	332904
3178822	3178845	19	+	26472758	KBM7	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	-0.48835049964182664	[2115,1669]	[640,619]	-4	hSpCas9	negative selection	332905
3178978	3179001	19	+	26472758	KBM7	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	0.5398396649435294	[617,420]	[331,365]	6	hSpCas9	negative selection	332906
3179365	3179388	19	-	26472758	KBM7	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-1.2979995871062002	[143,101]	[18,26]	-7	hSpCas9	negative selection	332907
3179530	3179553	19	-	26472758	KBM7	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.7121891394414659	[83,121]	[76,84]	7	hSpCas9	negative selection	332908
3179755	3179778	19	-	26472758	KBM7	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	-0.3629294057464687	[257,203]	[95,72]	-3	hSpCas9	negative selection	332909
3179330	3179353	19	-	26472758	KBM7	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	0.328626718404496	[667,788]	[399,467]	3	hSpCas9	negative selection	332910
3179494	3179517	19	+	26472758	KBM7	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	0.8904189643864868	[765,487]	[446,616]	8	hSpCas9	negative selection	332911
3179181	3179204	19	-	26472758	Raji	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-3.6739761781510603	[54]	[0]	-9	hSpCas9	negative selection	524020
3179568	3179591	19	-	26472758	Raji	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	-0.3780432917966423	[139]	[24]	-3	hSpCas9	negative selection	524021
3178785	3178808	19	+	26472758	Raji	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.7634291341562383	[395]	[155]	7	hSpCas9	negative selection	524022
3178822	3178845	19	+	26472758	Raji	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	0.2628588207254545	[746]	[207]	2	hSpCas9	negative selection	524023
3178978	3179001	19	+	26472758	Raji	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	0.12292438626937766	[276]	[69]	1	hSpCas9	negative selection	524024
3179365	3179388	19	-	26472758	Raji	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	0.6923460360947558	[47]	[17]	6	hSpCas9	negative selection	524025
3179530	3179553	19	-	26472758	Raji	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	1.2170080265480976	[75]	[40]	9	hSpCas9	negative selection	524026
3179755	3179778	19	-	26472758	Raji	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	-1.0625414660687131	[134]	[14]	-7	hSpCas9	negative selection	524027
3179330	3179353	19	-	26472758	Raji	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	0.29475367127532137	[410]	[116]	2	hSpCas9	negative selection	524028
3179494	3179517	19	+	26472758	Raji	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	-0.3197877195410995	[397]	[73]	-3	hSpCas9	negative selection	524029
3179181	3179204	19	-	26472758	K562	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-6.625945991916957	[116]	[0]	-9	hSpCas9	negative selection	715138
3179568	3179591	19	-	26472758	K562	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	0.00018191728677896535	[243]	[205]	0	hSpCas9	negative selection	715139
3178785	3178808	19	+	26472758	K562	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.5754939158009622	[565]	[711]	4	hSpCas9	negative selection	715140
3178822	3178845	19	+	26472758	K562	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	0.2893894868027076	[1515]	[1563]	2	hSpCas9	negative selection	715141
3178978	3179001	19	+	26472758	K562	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	-0.2410080995037947	[419]	[299]	-2	hSpCas9	negative selection	715142
3179365	3179388	19	-	26472758	K562	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-3.0103951713623784	[104]	[10]	-8	hSpCas9	negative selection	715143
3179530	3179553	19	-	26472758	K562	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.1529956999028521	[113]	[106]	1	hSpCas9	negative selection	715144
3179755	3179778	19	-	26472758	K562	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	0.6002170235706146	[260]	[333]	5	hSpCas9	negative selection	715145
3179330	3179353	19	-	26472758	K562	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	0.8285861360330125	[604]	[906]	7	hSpCas9	negative selection	715146
3179494	3179517	19	+	26472758	K562	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	0.5999844192540968	[389]	[498]	5	hSpCas9	negative selection	715147
3178876	3178899	19	+	26627737	DLD1	viability	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	0.159033336867983	[385]	[164,150,94]	1	hSpCas9	negative selection	803890
3179137	3179160	19	+	26627737	DLD1	viability	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-0.20690303946534727	[1467]	[460,570,198]	-2	hSpCas9	negative selection	803891
3179221	3179244	19	+	26627737	DLD1	viability	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	0.41409323528611375	[226]	[94,72,111]	4	hSpCas9	negative selection	803892
3179530	3179553	19	-	26627737	DLD1	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.5187343454357629	[362]	[32,130,300]	5	hSpCas9	negative selection	803893
3179668	3179691	19	-	26627737	DLD1	viability	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	1.2283490216782245	[55]	[39,58,26]	9	hSpCas9	negative selection	803894
3179707	3179730	19	+	26627737	DLD1	viability	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.07328617293467588	[1271]	[495,392,371]	0	hSpCas9	negative selection	803895
3178876	3178899	19	+	26627737	GBM cells	viability after 5 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	0.6247389114466915	[207]	[184,158]	8	hSpCas9	negative selection	886205
3179137	3179160	19	+	26627737	GBM cells	viability after 5 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-0.17457719038084085	[744]	[344,362]	-3	hSpCas9	negative selection	886206
3179221	3179244	19	+	26627737	GBM cells	viability after 5 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	0.0724501298803768	[132]	[77,71]	1	hSpCas9	negative selection	886207
3179530	3179553	19	-	26627737	GBM cells	viability after 5 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.3983435614549017	[248]	[209,141]	6	hSpCas9	negative selection	886208
3179668	3179691	19	-	26627737	GBM cells	viability after 5 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	0.964502216513262	[42]	[30,58]	9	hSpCas9	negative selection	886209
3179707	3179730	19	+	26627737	GBM cells	viability after 5 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	-0.30260935440316294	[651]	[332,233]	-5	hSpCas9	negative selection	886210
3178876	3178899	19	+	26627737	GBM cells	viability after 13 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	0.563015494490263	[207]	[174,159]	7	hSpCas9	negative selection	968520
3179137	3179160	19	+	26627737	GBM cells	viability after 13 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-0.11070987593532888	[744]	[407,346]	-1	hSpCas9	negative selection	968521
3179221	3179244	19	+	26627737	GBM cells	viability after 13 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	0.1666706909618827	[132]	[80,80]	2	hSpCas9	negative selection	968522
3179530	3179553	19	-	26627737	GBM cells	viability after 13 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.45218996542516837	[248]	[154,52]	-5	hSpCas9	negative selection	968523
3179668	3179691	19	-	26627737	GBM cells	viability after 13 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	1.2344953209290797	[42]	[55,53]	9	hSpCas9	negative selection	968524
3179707	3179730	19	+	26627737	GBM cells	viability after 13 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	-0.1610997089378332	[651]	[322,310]	-2	hSpCas9	negative selection	968525
3178876	3178899	19	+	26627737	GBM cells	viability after 21 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	0.4015417987186453	[207]	[142,154]	4	hSpCas9	negative selection	1050835
3179137	3179160	19	+	26627737	GBM cells	viability after 21 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-0.22632774971385206	[744]	[369,323]	-2	hSpCas9	negative selection	1050836
3179221	3179244	19	+	26627737	GBM cells	viability after 21 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	-0.15861224607485758	[132]	[70,58]	-1	hSpCas9	negative selection	1050837
3179530	3179553	19	-	26627737	GBM cells	viability after 21 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.20256972178070917	[248]	[127,107]	-2	hSpCas9	negative selection	1050838
3179668	3179691	19	-	26627737	GBM cells	viability after 21 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	0.7882666633840929	[42]	[43,36]	7	hSpCas9	negative selection	1050839
3179707	3179730	19	+	26627737	GBM cells	viability after 21 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.08532640191727414	[651]	[403,349]	0	hSpCas9	negative selection	1050840
3178876	3178899	19	+	26627737	RPE1	viability after 9 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	1.8844752099722686	[387]	[661,172]	8	hSpCas9	negative selection	1133150
3179137	3179160	19	+	26627737	RPE1	viability after 9 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-1.0817630924207602	[4369]	[269,1131]	-7	hSpCas9	negative selection	1133151
3179221	3179244	19	+	26627737	RPE1	viability after 9 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	-1.0636265603871213	[475]	[62,81]	-6	hSpCas9	negative selection	1133152
3179530	3179553	19	-	26627737	RPE1	viability after 9 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-1.648189979935475	[1320]	[41,247]	-8	hSpCas9	negative selection	1133153
3179668	3179691	19	-	26627737	RPE1	viability after 9 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	1.681685221294576	[116]	[89,152]	8	hSpCas9	negative selection	1133154
3179707	3179730	19	+	26627737	RPE1	viability after 9 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.7122962360628986	[1464]	[602,942]	5	hSpCas9	negative selection	1133155
3178876	3178899	19	+	26627737	RPE1	viability after 12 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	1.9183550040790038	[387]	[581,194]	8	hSpCas9	negative selection	1215465
3179137	3179160	19	+	26627737	RPE1	viability after 12 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-1.0936436669754415	[4369]	[333,778]	-6	hSpCas9	negative selection	1215466
3179221	3179244	19	+	26627737	RPE1	viability after 12 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	-1.3907420255520342	[475]	[23,74]	-7	hSpCas9	negative selection	1215467
3179530	3179553	19	-	26627737	RPE1	viability after 12 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-3.2419351556257694	[1320]	[20,54]	-9	hSpCas9	negative selection	1215468
3179668	3179691	19	-	26627737	RPE1	viability after 12 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	1.9212570598473155	[116]	[137,98]	8	hSpCas9	negative selection	1215469
3179707	3179730	19	+	26627737	RPE1	viability after 12 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.8883530720521438	[1464]	[917,527]	5	hSpCas9	negative selection	1215470
3178876	3178899	19	+	26627737	RPE1	viability after 15 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	1.9919654761319534	[387]	[515,359]	8	hSpCas9	negative selection	1297780
3179137	3179160	19	+	26627737	RPE1	viability after 15 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-1.2566005800863818	[4369]	[439,591]	-7	hSpCas9	negative selection	1297781
3179221	3179244	19	+	26627737	RPE1	viability after 15 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	-1.1864481228058144	[475]	[49,67]	-6	hSpCas9	negative selection	1297782
3179530	3179553	19	-	26627737	RPE1	viability after 15 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-1.7612530908061208	[1320]	[68,149]	-8	hSpCas9	negative selection	1297783
3179668	3179691	19	-	26627737	RPE1	viability after 15 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	1.907947565523243	[116]	[168,80]	8	hSpCas9	negative selection	1297784
3179707	3179730	19	+	26627737	RPE1	viability after 15 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	1.0267198995271523	[1464]	[825,861]	6	hSpCas9	negative selection	1297785
3178876	3178899	19	+	26627737	RPE1	viability after 18 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	1.708127642830254	[387]	[505,166]	8	hSpCas9	negative selection	1380095
3179137	3179160	19	+	26627737	RPE1	viability after 18 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-0.8040132620283944	[4369]	[484,878]	-5	hSpCas9	negative selection	1380096
3179221	3179244	19	+	26627737	RPE1	viability after 18 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	-0.9513587039757886	[475]	[78,52]	-5	hSpCas9	negative selection	1380097
3179530	3179553	19	-	26627737	RPE1	viability after 18 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.6533984981751758	[1320]	[201,252]	-4	hSpCas9	negative selection	1380098
3179668	3179691	19	-	26627737	RPE1	viability after 18 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	2.2367731789540293	[116]	[201,91]	9	hSpCas9	negative selection	1380099
3179707	3179730	19	+	26627737	RPE1	viability after 18 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.5956809416827367	[1464]	[537,660]	4	hSpCas9	negative selection	1380100
3178876	3178899	19	+	26627737	HeLa	viability after 8 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	0.9065955110066403	[360]	[91,587,167]	7	hSpCas9	negative selection	1462410
3179137	3179160	19	+	26627737	HeLa	viability after 8 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.010994730749682713	[1572]	[828,554,713]	0	hSpCas9	negative selection	1462411
3179221	3179244	19	+	26627737	HeLa	viability after 8 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	-0.6559366455936788	[302]	[151,58,56]	-6	hSpCas9	negative selection	1462412
3179530	3179553	19	-	26627737	HeLa	viability after 8 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.021795533342310824	[368]	[241,4,239]	0	hSpCas9	negative selection	1462413
3179668	3179691	19	-	26627737	HeLa	viability after 8 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	-2.023642072067982	[188]	[17,33,8]	-9	hSpCas9	negative selection	1462414
3179707	3179730	19	+	26627737	HeLa	viability after 8 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.8176904352437155	[613]	[693,491,288]	6	hSpCas9	negative selection	1462415
3178876	3178899	19	+	26627737	HeLa	viability after 12 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	0.4029834111425196	[360]	[46,389,129]	3	hSpCas9	negative selection	1544725
3179137	3179160	19	+	26627737	HeLa	viability after 12 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-0.20747824705417872	[1572]	[653,615,415]	-2	hSpCas9	negative selection	1544726
3179221	3179244	19	+	26627737	HeLa	viability after 12 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	-0.36484438831860233	[302]	[144,135,7]	-3	hSpCas9	negative selection	1544727
3179530	3179553	19	-	26627737	HeLa	viability after 12 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.5696931278510559	[368]	[80,98,127]	-5	hSpCas9	negative selection	1544728
3179668	3179691	19	-	26627737	HeLa	viability after 12 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	-1.6495981090932705	[188]	[8,26,37]	-9	hSpCas9	negative selection	1544729
3179707	3179730	19	+	26627737	HeLa	viability after 12 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.890025407602713	[613]	[318,378,717]	7	hSpCas9	negative selection	1544730
3178876	3178899	19	+	26627737	HeLa	viability after 15 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	0.0113265351913103	[360]	[50,253,139]	0	hSpCas9	negative selection	1627040
3179137	3179160	19	+	26627737	HeLa	viability after 15 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.23891606859555248	[1572]	[933,415,927]	2	hSpCas9	negative selection	1627041
3179221	3179244	19	+	26627737	HeLa	viability after 15 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	-0.32566132933744674	[302]	[87,113,92]	-3	hSpCas9	negative selection	1627042
3179530	3179553	19	-	26627737	HeLa	viability after 15 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.1651404349169096	[368]	[189,134,180]	1	hSpCas9	negative selection	1627043
3179668	3179691	19	-	26627737	HeLa	viability after 15 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	-1.5124317447072144	[188]	[0,19,62]	-8	hSpCas9	negative selection	1627044
3179707	3179730	19	+	26627737	HeLa	viability after 15 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.6226350944815986	[613]	[286,457,412]	5	hSpCas9	negative selection	1627045
3178876	3178899	19	+	26627737	HeLa	viability after 18 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	-0.026592296559077716	[360]	[30,204,139]	0	hSpCas9	negative selection	1709355
3179137	3179160	19	+	26627737	HeLa	viability after 18 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.2492326166900165	[1572]	[635,345,927]	2	hSpCas9	negative selection	1709356
3179221	3179244	19	+	26627737	HeLa	viability after 18 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	-0.3481486912220111	[302]	[53,96,92]	-3	hSpCas9	negative selection	1709357
3179530	3179553	19	-	26627737	HeLa	viability after 18 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.20204557018731956	[368]	[134,112,180]	1	hSpCas9	negative selection	1709358
3179668	3179691	19	-	26627737	HeLa	viability after 18 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	-1.4938345613271307	[188]	[0,16,62]	-8	hSpCas9	negative selection	1709359
3179707	3179730	19	+	26627737	HeLa	viability after 18 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.6207910254188831	[613]	[190,379,412]	5	hSpCas9	negative selection	1709360
3178876	3178899	19	+	26627737	HCT116	viability after 6 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	1.5251168370939705	[526]	[367,166]	7	hSpCas9	negative selection	1791670
3179137	3179160	19	+	26627737	HCT116	viability after 6 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.7150817421667353	[1728]	[1131,67]	4	hSpCas9	negative selection	1791671
3179221	3179244	19	+	26627737	HCT116	viability after 6 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	-1.5378609015904428	[787]	[61,31]	-7	hSpCas9	negative selection	1791672
3179530	3179553	19	-	26627737	HCT116	viability after 6 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	1.7477664909330515	[529]	[157,346]	8	hSpCas9	negative selection	1791673
3179668	3179691	19	-	26627737	HCT116	viability after 6 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	-0.23399163564437186	[136]	[7,23]	-1	hSpCas9	negative selection	1791674
3179707	3179730	19	+	26627737	HCT116	viability after 6 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.5731482154884384	[1629]	[562,280]	3	hSpCas9	negative selection	1791675
3178876	3178899	19	+	26627737	HCT116	viability after 8 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	-0.6465479157263886	[538]	[134,308,124]	-7	hSpCas9	negative selection	1873985
3179137	3179160	19	+	26627737	HCT116	viability after 8 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.23174207600741914	[767]	[514,469,505]	2	hSpCas9	negative selection	1873986
3179221	3179244	19	+	26627737	HCT116	viability after 8 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	0.6548951538752253	[135]	[87,110,153]	6	hSpCas9	negative selection	1873987
3179530	3179553	19	-	26627737	HCT116	viability after 8 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.06540214485469958	[394]	[299,144,180]	0	hSpCas9	negative selection	1873988
3179668	3179691	19	-	26627737	HCT116	viability after 8 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	-0.9880854826428369	[162]	[46,53,34]	-8	hSpCas9	negative selection	1873989
3179707	3179730	19	+	26627737	HCT116	viability after 8 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.25584318589460187	[527]	[407,430,205]	3	hSpCas9	negative selection	1873990
3178876	3178899	19	+	26627737	HCT116	viability after 9 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	1.769787948506411	[526]	[485,474]	9	hSpCas9	negative selection	1956300
3179137	3179160	19	+	26627737	HCT116	viability after 9 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-0.1537021800522198	[1728]	[700,188]	-1	hSpCas9	negative selection	1956301
3179221	3179244	19	+	26627737	HCT116	viability after 9 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	-0.4357480467261067	[787]	[216,106]	-3	hSpCas9	negative selection	1956302
3179530	3179553	19	-	26627737	HCT116	viability after 9 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.12740325235234942	[529]	[86,207]	1	hSpCas9	negative selection	1956303
3179668	3179691	19	-	26627737	HCT116	viability after 9 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	0.8566591316308314	[136]	[144,3]	6	hSpCas9	negative selection	1956304
3179707	3179730	19	+	26627737	HCT116	viability after 9 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	-0.8788438923372727	[1629]	[253,222]	-6	hSpCas9	negative selection	1956305
3178876	3178899	19	+	26627737	HCT116	viability after 12 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	-0.318160109691607	[538]	[244,266,168]	-3	hSpCas9	negative selection	2038615
3179137	3179160	19	+	26627737	HCT116	viability after 12 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.27830025702300265	[767]	[312,780,396]	3	hSpCas9	negative selection	2038616
3179221	3179244	19	+	26627737	HCT116	viability after 12 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	1.3562686788454916	[135]	[264,110,163]	9	hSpCas9	negative selection	2038617
3179530	3179553	19	-	26627737	HCT116	viability after 12 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.5367669770219161	[394]	[241,233,430]	5	hSpCas9	negative selection	2038618
3179668	3179691	19	-	26627737	HCT116	viability after 12 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	-1.1344652996903721	[162]	[37,32,45]	-8	hSpCas9	negative selection	2038619
3179707	3179730	19	+	26627737	HCT116	viability after 12 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.5379841776930182	[527]	[431,357,414]	5	hSpCas9	negative selection	2038620
3178876	3178899	19	+	26627737	HCT116	viability after 15 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	-0.6799302351458288	[538]	[254,290,42]	-6	hSpCas9	negative selection	2120930
3179137	3179160	19	+	26627737	HCT116	viability after 15 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.08130218809284417	[767]	[548,401,458]	0	hSpCas9	negative selection	2120931
3179221	3179244	19	+	26627737	HCT116	viability after 15 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	0.7199520827815933	[135]	[195,140,57]	6	hSpCas9	negative selection	2120932
3179530	3179553	19	-	26627737	HCT116	viability after 15 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.4512331103784851	[394]	[341,172,417]	4	hSpCas9	negative selection	2120933
3179668	3179691	19	-	26627737	HCT116	viability after 15 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	-1.1870968295971958	[162]	[68,38,18]	-8	hSpCas9	negative selection	2120934
3179707	3179730	19	+	26627737	HCT116	viability after 15 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.31389909433391827	[527]	[264,460,390]	3	hSpCas9	negative selection	2120935
3178876	3178899	19	+	26627737	HCT116	viability after 18 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	-0.8950926326243521	[538]	[162,167,84]	-7	hSpCas9	negative selection	2203245
3179137	3179160	19	+	26627737	HCT116	viability after 18 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.3488913263665576	[767]	[273,456,698]	3	hSpCas9	negative selection	2203246
3179221	3179244	19	+	26627737	HCT116	viability after 18 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	1.1078534035772267	[135]	[153,111,161]	8	hSpCas9	negative selection	2203247
3179530	3179553	19	-	26627737	HCT116	viability after 18 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.2407625980477543	[394]	[182,159,140]	-2	hSpCas9	negative selection	2203248
3179668	3179691	19	-	26627737	HCT116	viability after 18 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	-0.46936604542631266	[162]	[69,57,41]	-4	hSpCas9	negative selection	2203249
3179707	3179730	19	+	26627737	HCT116	viability after 18 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.2563825214490535	[527]	[305,361,239]	2	hSpCas9	negative selection	2203250
3178601	3178624	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCCCCAGCGCGTTGGCTCCAGG	S1PR4	ENSG00000125910	3.266408634848471	[4,228]	[1,522]	8	dCas9-VP64	positive selection	2433787
3178626	3178649	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCGGGTGGGGGCCGACCGTTGG	S1PR4	ENSG00000125910	1.9481359979551676	[165,52]	[167,10]	6	dCas9-VP64	positive selection	2433788
3178577	3178600	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTGGGGGTCCTCACAGCCAGGG	S1PR4	ENSG00000125910	2.7761650522830585	[31,38]	[54,52]	8	dCas9-VP64	positive selection	2433789
3178601	3178624	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCCCCAGCGCGTTGGCTCCAGG	S1PR4	ENSG00000125910	0.7161017540335566	[42,43]	[38,8]	5	dCas9-VP64	positive selection	2529042
3178626	3178649	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCGGGTGGGGGCCGACCGTTGG	S1PR4	ENSG00000125910	-0.15997641767889448	[46,62]	[12,17]	-1	dCas9-VP64	positive selection	2529043
3178577	3178600	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTGGGGGTCCTCACAGCCAGGG	S1PR4	ENSG00000125910	-0.7608717143986172	[86,56]	[18,7]	-7	dCas9-VP64	positive selection	2529044
3178966	3178989	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAGTTCTCCAGCACCACCAGG	S1PR4	ENSG00000125910	0.0885314452644348	[5,5]	[5,5]	1	hSpCas9	positive selection	3018515
3178809	3178832	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGACTCGGGGGCCACCGGGG	S1PR4	ENSG00000125910	-0.388428101604201	[2,2]	[2,0]	-5	hSpCas9	positive selection	3018516
3178786	3178809	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.08254277953206803	[2,2]	[2,2]	1	hSpCas9	positive selection	3018517
3178858	3178881	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTAGTGCAGAACAATGAGCCGG	S1PR4	ENSG00000125910	0.24550077293266276	[5,5]	[5,5]	5	hSpCas9	positive selection	3018518
3178966	3178989	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAGTTCTCCAGCACCACCAGG	S1PR4	ENSG00000125910	0.6583890392602085	[5,5]	[6,6]	9	hSpCas9	positive selection	3086373
3178809	3178832	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGACTCGGGGGCCACCGGGG	S1PR4	ENSG00000125910	-0.8194509367903341	[2,2]	[1,0]	-9	hSpCas9	positive selection	3086374
3178786	3178809	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	-0.4179312368687449	[2,2]	[2,0]	-6	hSpCas9	positive selection	3086375
3178858	3178881	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTAGTGCAGAACAATGAGCCGG	S1PR4	ENSG00000125910	0.3171533584862673	[5,5]	[5,3]	5	hSpCas9	positive selection	3086376
3179814	3179837		-	24336571	A375	resistance to PLX after 7 days	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.1137585266097304	[6,8]	[7,6]	-4	hSpCas9	positive selection	3142432
3179268	3179291		-	24336571	A375	resistance to PLX after 7 days	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.08489560130871787	[4,5]	[4,5]	-3	hSpCas9	positive selection	3142433
3179814	3179837		-	24336571	A375	resistance to PLX after 14 days	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.47828450648133325	[11,6]	[2,2]	-6	hSpCas9	positive selection	3200225
3179268	3179291		-	24336571	A375	resistance to PLX after 14 days	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.3250569772645625	[4,5]	[2,2]	3	hSpCas9	positive selection	3200226
3179814	3179837		-	24336571	A375	viability after 7 days	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.6312128577609747	[4]	[6,8]	8	hSpCas9	negative selection	3258018
3179268	3179291		-	24336571	A375	viability after 7 days	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.15645288934946233	[6]	[4,5]	-2	hSpCas9	negative selection	3258019
3179814	3179837		-	24336571	A375	viability after 14 days	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.8572066964215163	[4]	[11,6]	9	hSpCas9	negative selection	3315811
3179268	3179291		-	24336571	A375	viability after 14 days	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.1479424100149611	[6]	[4,5]	-2	hSpCas9	negative selection	3315812
3179814	3179837	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.7978945928085378	[87,87]	[0,0]	4	hSpCas9	positive selection	3391078
3179683	3179706	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.47059424311736403	[211,211]	[0,0]	-3	hSpCas9	positive selection	3391079
3179861	3179884	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	4.372803428865771	[95,95]	[12,12]	9	hSpCas9	positive selection	3391080
3178966	3178989	19	-	26780180	HT29	viability (Avana library 4 designs)	GCAAGTTCTCCAGCACCACCAGG	S1PR4	ENSG00000125910	0.108531759291224	[]	[]	0	hSpCas9	negative selection	3456920
3178809	3178832	19	-	26780180	HT29	viability (Avana library 4 designs)	GCAGGACTCGGGGGCCACCGGGG	S1PR4	ENSG00000125910	3.14670055554906	[]	[]	8	hSpCas9	negative selection	3456921
3178785	3178808	19	+	26780180	HT29	viability (Avana library 4 designs)	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	1.56189799430573	[]	[]	6	hSpCas9	negative selection	3456922
3178858	3178881	19	-	26780180	HT29	viability (Avana library 4 designs)	TGTAGTGCAGAACAATGAGCCGG	S1PR4	ENSG00000125910	1.54972367939965	[]	[]	6	hSpCas9	negative selection	3456923
3178785	3178808	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	1.00464808745962	[]	[]	1	hSpCas9	negative selection	3555628
3178809	3178832	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGACTCGGGGGCCACCGGGG	S1PR4	ENSG00000125910	2.48840951284926	[]	[]	3	hSpCas9	negative selection	3555629
3178966	3178989	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAGTTCTCCAGCACCACCAGG	S1PR4	ENSG00000125910	0.422450627652781	[]	[]	0	hSpCas9	negative selection	3555630
3178858	3178881	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTAGTGCAGAACAATGAGCCGG	S1PR4	ENSG00000125910	-9.18169551434372	[]	[]	-7	hSpCas9	negative selection	3555631
3179193	3179216	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCCTGCTCTTCACTGCAGGG	S1PR4	ENSG00000125910	2.60434505362193	[]	[]	4	hSpCas9	negative selection	3555632
3179272	3179295	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCGATGAAGCCGTAGACGCGG	S1PR4	ENSG00000125910	3.86967746702768	[]	[]	6	hSpCas9	negative selection	3555633
3178785	3178808	19	+	26780180	A375	viability (Avana lentiGuide)	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	1.25891417979006	[]	[]	1	hSpCas9	negative selection	3664287
3178809	3178832	19	-	26780180	A375	viability (Avana lentiGuide)	GCAGGACTCGGGGGCCACCGGGG	S1PR4	ENSG00000125910	17.2366895345886	[]	[]	8	hSpCas9	negative selection	3664288
3178966	3178989	19	-	26780180	A375	viability (Avana lentiGuide)	GCAAGTTCTCCAGCACCACCAGG	S1PR4	ENSG00000125910	-2.79356376648601	[]	[]	-5	hSpCas9	negative selection	3664289
3178858	3178881	19	-	26780180	A375	viability (Avana lentiGuide)	TGTAGTGCAGAACAATGAGCCGG	S1PR4	ENSG00000125910	6.82699166157025	[]	[]	5	hSpCas9	negative selection	3664290
3179193	3179216	19	+	26780180	A375	viability (Avana lentiGuide)	TCAGCCTGCTCTTCACTGCAGGG	S1PR4	ENSG00000125910	-1.1456829316804	[]	[]	-2	hSpCas9	negative selection	3664291
3179272	3179295	19	-	26780180	A375	viability (Avana lentiGuide)	GGCCGATGAAGCCGTAGACGCGG	S1PR4	ENSG00000125910	1.38489936158404	[]	[]	1	hSpCas9	negative selection	3664292
3178785	3178808	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.22053576208176454	[3]	[4,4]	6	hSpCas9	positive selection	3772894
3178809	3178832	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGACTCGGGGGCCACCGGGG	S1PR4	ENSG00000125910	0.005790694747782932	[3]	[3,3]	0	hSpCas9	positive selection	3772895
3178966	3178989	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAGTTCTCCAGCACCACCAGG	S1PR4	ENSG00000125910	-0.04013419292146661	[5]	[6,4]	0	hSpCas9	positive selection	3772896
3178858	3178881	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTAGTGCAGAACAATGAGCCGG	S1PR4	ENSG00000125910	-0.20417627638226898	[6]	[5,5]	-3	hSpCas9	positive selection	3772897
3179193	3179216	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCCTGCTCTTCACTGCAGGG	S1PR4	ENSG00000125910	0.21339580243362619	[6]	[6,6]	6	hSpCas9	positive selection	3772898
3179272	3179295	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCGATGAAGCCGTAGACGCGG	S1PR4	ENSG00000125910	0.19689335547349446	[5]	[5,6]	5	hSpCas9	positive selection	3772899
3178785	3178808	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	-0.04340662851675303	[4]	[3,4]	0	hSpCas9	positive selection	3881501
3178809	3178832	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGACTCGGGGGCCACCGGGG	S1PR4	ENSG00000125910	-1.1432152026788691	[4]	[2,0]	-8	hSpCas9	positive selection	3881502
3178966	3178989	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAGTTCTCCAGCACCACCAGG	S1PR4	ENSG00000125910	0.28467639601075184	[7]	[8,7]	7	hSpCas9	positive selection	3881503
3178858	3178881	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTAGTGCAGAACAATGAGCCGG	S1PR4	ENSG00000125910	-0.10056245179293988	[7]	[6,5]	-1	hSpCas9	positive selection	3881504
3179193	3179216	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCCTGCTCTTCACTGCAGGG	S1PR4	ENSG00000125910	0.16276689755065216	[6]	[6,6]	4	hSpCas9	positive selection	3881505
3179272	3179295	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCGATGAAGCCGTAGACGCGG	S1PR4	ENSG00000125910	0.1441515992317225	[6]	[6,5]	3	hSpCas9	positive selection	3881506
3179261	3179284	19	+	26780180	A375	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.60467465383321	[]	[]	2	hSpCas9	negative selection	3991519
3179814	3179837	19	-	26780180	A375	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.859517294040237	[]	[]	3	hSpCas9	negative selection	3991520
3179861	3179884	19	-	26780180	A375	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	1.13072063473243	[]	[]	5	hSpCas9	negative selection	3991521
3179268	3179291	19	-	26780180	A375	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.791715307290299	[]	[]	3	hSpCas9	negative selection	3991522
3179068	3179091	19	-	26780180	A375	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.661340158758062	[]	[]	2	hSpCas9	negative selection	3991523
3179683	3179706	19	-	26780180	A375	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	1.20233424288435	[]	[]	6	hSpCas9	negative selection	3991524
3179261	3179284	19	+	26780180	HT29	viability (GeCKOv2 library)	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.638632773515483	[]	[]	2	hSpCas9	negative selection	4099485
3179814	3179837	19	-	26780180	HT29	viability (GeCKOv2 library)	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	1.65989342020893	[]	[]	8	hSpCas9	negative selection	4099486
3179861	3179884	19	-	26780180	HT29	viability (GeCKOv2 library)	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	0.839264919806252	[]	[]	3	hSpCas9	negative selection	4099487
3179268	3179291	19	-	26780180	HT29	viability (GeCKOv2 library)	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	1.47708260078005	[]	[]	7	hSpCas9	negative selection	4099488
3179068	3179091	19	-	26780180	HT29	viability (GeCKOv2 library)	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	1.11366696747219	[]	[]	5	hSpCas9	negative selection	4099489
3179683	3179706	19	-	26780180	HT29	viability (GeCKOv2 library)	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.945869743207711	[]	[]	4	hSpCas9	negative selection	4099490
3179814	3179837	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.2106999938812677	[2]	[0,1]	-5	hSpCas9	positive selection	4168170
3179268	3179291	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.27017449546631656	[2]	[1,1]	-6	hSpCas9	positive selection	4168171
3179814	3179837	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.02555830218809596	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4232192
3179268	3179291	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	1.0255571095772813	[1]	[0,4,1,0]	7	hSpCas9	positive selection	4232193
3179268	3179291	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.2866646565550107	[1]	[1,0]	-5	hSpCas9	positive selection	4296232
3179261	3179284	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	-0.06490964742786248	[2]	[2,0]	-1	hSpCas9	positive selection	4296233
3179068	3179091	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.06530602493565707	[1]	[2,0]	1	hSpCas9	positive selection	4296234
3179814	3179837	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.16231598732409952	[2]	[2,1]	3	hSpCas9	positive selection	4360486
3179683	3179706	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.12873525736355737	[3]	[3,2]	2	hSpCas9	positive selection	4360487
3179861	3179884	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.5492029816965267	[2]	[2,0]	-8	hSpCas9	positive selection	4360488
3178868	3178890	19	+	27760321	OCIAML3	viability	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	0.19607181613469413	[390,372]	[241,473]	2	hSpCas9	negative selection	4436632
3179007	3179029	19	-	27760321	OCIAML3	viability	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	-0.15776661278873721	[681,661]	[419,539]	-2	hSpCas9	negative selection	4436633
3179072	3179094	19	+	27760321	OCIAML3	viability	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	0.2633861597155157	[523,438]	[444,456]	3	hSpCas9	negative selection	4436634
3179268	3179290	19	-	27760321	OCIAML3	viability	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.09500296252276112	[470,368]	[255,369]	-1	hSpCas9	negative selection	4436635
3179358	3179380	19	-	27760321	OCIAML3	viability	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	0.3011209542630633	[594,491]	[368,719]	3	hSpCas9	negative selection	4436636
3178868	3178890	19	+	27760321	OCIAML2	viability	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	0.16949174101491826	[390,372]	[303,405]	2	hSpCas9	negative selection	4520095
3179007	3179029	19	-	27760321	OCIAML2	viability	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	-0.15726339675546264	[681,661]	[396,608]	-2	hSpCas9	negative selection	4520096
3179072	3179094	19	+	27760321	OCIAML2	viability	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	0.3945895527157891	[523,438]	[361,704]	5	hSpCas9	negative selection	4520097
3179268	3179290	19	-	27760321	OCIAML2	viability	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.05683505180817493	[470,368]	[257,411]	0	hSpCas9	negative selection	4520098
3179358	3179380	19	-	27760321	OCIAML2	viability	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	0.4999640666697228	[594,491]	[621,614]	6	hSpCas9	negative selection	4520099
3178868	3178890	19	+	27760321	MV411	viability	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	1.3649820348886041	[390,372]	[616,699]	8	hSpCas9	negative selection	4603558
3179007	3179029	19	-	27760321	MV411	viability	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	-0.5466689162035182	[681,661]	[320,278]	-4	hSpCas9	negative selection	4603559
3179072	3179094	19	+	27760321	MV411	viability	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	0.24152794826307603	[523,438]	[326,444]	1	hSpCas9	negative selection	4603560
3179268	3179290	19	-	27760321	MV411	viability	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.21180035376309975	[470,368]	[367,244]	1	hSpCas9	negative selection	4603561
3179358	3179380	19	-	27760321	MV411	viability	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	-0.6897093688898865	[594,491]	[172,293]	-5	hSpCas9	negative selection	4603562
3178868	3178890	19	+	27760321	HL60	viability	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	0.21637534864188301	[390,372]	[363,361]	2	hSpCas9	negative selection	4687021
3179007	3179029	19	-	27760321	HL60	viability	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	0.20910721394935372	[681,661]	[614,657]	2	hSpCas9	negative selection	4687022
3179072	3179094	19	+	27760321	HL60	viability	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	0.033074401801399894	[523,438]	[395,405]	0	hSpCas9	negative selection	4687023
3179268	3179290	19	-	27760321	HL60	viability	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.9124495193746855	[470,368]	[182,178]	-7	hSpCas9	negative selection	4687024
3179358	3179380	19	-	27760321	HL60	viability	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	-0.2757460283979024	[594,491]	[400,326]	-3	hSpCas9	negative selection	4687025
3178868	3178890	19	+	27760321	HT1080	viability	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	-0.6642963945833487	[372,290]	[92,72]	-3	hSpCas9	negative selection	4770484
3179007	3179029	19	-	27760321	HT1080	viability	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	0.3608174388157448	[661,516]	[355,241]	1	hSpCas9	negative selection	4770485
3179072	3179094	19	+	27760321	HT1080	viability	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	-0.503409192650418	[438,342]	[96,123]	-2	hSpCas9	negative selection	4770486
3179268	3179290	19	-	27760321	HT1080	viability	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.07684413496744187	[368,287]	[127,148]	0	hSpCas9	negative selection	4770487
3179358	3179380	19	-	27760321	HT1080	viability	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	0.11156792997114401	[491,383]	[230,141]	0	hSpCas9	negative selection	4770488
3178868	3178890	19	+	27760321	HT29	viability after 7 days	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	0.052251225552471636	[372,290]	[554,594,200]	0	hSpCas9	negative selection	4853947
3179007	3179029	19	-	27760321	HT29	viability after 7 days	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	-0.1911211868179692	[661,516]	[598,701,679]	-3	hSpCas9	negative selection	4853948
3179072	3179094	19	+	27760321	HT29	viability after 7 days	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	0.29607832921304345	[438,342]	[715,467,678]	4	hSpCas9	negative selection	4853949
3179268	3179290	19	-	27760321	HT29	viability after 7 days	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.37121159782604485	[368,287]	[557,574,507]	5	hSpCas9	negative selection	4853950
3179358	3179380	19	-	27760321	HT29	viability after 7 days	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	0.3741633818152933	[491,383]	[984,542,697]	6	hSpCas9	negative selection	4853951
3178868	3178890	19	+	27760321	HT29	viability after 25 days	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	-0.09415529911501758	[372,290]	[255,391,431]	-1	hSpCas9	negative selection	4937410
3179007	3179029	19	-	27760321	HT29	viability after 25 days	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	-0.6127284399629153	[661,516]	[381,439,509]	-5	hSpCas9	negative selection	4937411
3179072	3179094	19	+	27760321	HT29	viability after 25 days	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	0.22363445113274738	[438,342]	[424,586,562]	2	hSpCas9	negative selection	4937412
3179268	3179290	19	-	27760321	HT29	viability after 25 days	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.4305288553173535	[368,287]	[353,296,167]	-4	hSpCas9	negative selection	4937413
3179358	3179380	19	-	27760321	HT29	viability after 25 days	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	-0.5178383172275096	[491,383]	[268,385,403]	-5	hSpCas9	negative selection	4937414
3178868	3178890	19	+	27760321	HT29	viability after 22 days	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	0.1071183602054786	[372,290]	[413,423,401]	1	hSpCas9	negative selection	5020873
3179007	3179029	19	-	27760321	HT29	viability after 22 days	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	-0.47131903334656405	[661,516]	[592,594,281]	-4	hSpCas9	negative selection	5020874
3179072	3179094	19	+	27760321	HT29	viability after 22 days	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	0.028456365922862256	[438,342]	[354,360,671]	0	hSpCas9	negative selection	5020875
3179268	3179290	19	-	27760321	HT29	viability after 22 days	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.34487572386790855	[368,287]	[356,183,354]	-3	hSpCas9	negative selection	5020876
3179358	3179380	19	-	27760321	HT29	viability after 22 days	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	0.29989171360572975	[491,383]	[512,839,518]	3	hSpCas9	negative selection	5020877
3178868	3178890	19	+	27760321	HT29	viability after 19 days	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	0.2812821734296893	[372,290]	[480,174,719]	2	hSpCas9	negative selection	5104336
3179007	3179029	19	-	27760321	HT29	viability after 19 days	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	-0.8606208012466994	[661,516]	[350,481,281]	-6	hSpCas9	negative selection	5104337
3179072	3179094	19	+	27760321	HT29	viability after 19 days	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	0.4763981670230853	[438,342]	[666,237,952]	5	hSpCas9	negative selection	5104338
3179268	3179290	19	-	27760321	HT29	viability after 19 days	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-1.2110828987879332	[368,287]	[308,81,112]	-7	hSpCas9	negative selection	5104339
3179358	3179380	19	-	27760321	HT29	viability after 19 days	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	-0.11386977028079776	[491,383]	[437,730,225]	-1	hSpCas9	negative selection	5104340
3178868	3178890	19	+	27760321	HT29	viability after 16 days	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	-0.25119741306702414	[372,290]	[316,336,281]	-3	hSpCas9	negative selection	5187799
3179007	3179029	19	-	27760321	HT29	viability after 16 days	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	-0.05267545534886642	[661,516]	[670,863,369]	0	hSpCas9	negative selection	5187800
3179072	3179094	19	+	27760321	HT29	viability after 16 days	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	0.3857558632408536	[438,342]	[771,594,365]	4	hSpCas9	negative selection	5187801
3179268	3179290	19	-	27760321	HT29	viability after 16 days	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.7934679986833969	[368,287]	[441,128,88]	-6	hSpCas9	negative selection	5187802
3179358	3179380	19	-	27760321	HT29	viability after 16 days	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	0.41080933293091093	[491,383]	[771,792,396]	4	hSpCas9	negative selection	5187803
3178868	3178890	19	+	27760321	HT29	viability after 13 days	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	-0.34852264842714337	[372,290]	[252,308,342]	-4	hSpCas9	negative selection	5271262
3179007	3179029	19	-	27760321	HT29	viability after 13 days	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	-0.7167274589712488	[661,516]	[387,351,502]	-6	hSpCas9	negative selection	5271263
3179072	3179094	19	+	27760321	HT29	viability after 13 days	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	0.4354533549684702	[438,342]	[573,782,490]	5	hSpCas9	negative selection	5271264
3179268	3179290	19	-	27760321	HT29	viability after 13 days	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.20130997024940142	[368,287]	[415,431,156]	-2	hSpCas9	negative selection	5271265
3179358	3179380	19	-	27760321	HT29	viability after 13 days	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	-0.036080804275002154	[491,383]	[702,267,513]	0	hSpCas9	negative selection	5271266
3178868	3178890	19	+	27760321	HT29	viability after 10 days	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	0.13316354433797045	[372,290]	[556,514,296]	1	hSpCas9	negative selection	5354725
3179007	3179029	19	-	27760321	HT29	viability after 10 days	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	-0.937362596480047	[661,516]	[344,481,329]	-7	hSpCas9	negative selection	5354726
3179072	3179094	19	+	27760321	HT29	viability after 10 days	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	0.20924505479373046	[438,342]	[725,608,363]	2	hSpCas9	negative selection	5354727
3179268	3179290	19	-	27760321	HT29	viability after 10 days	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.0029852387527045943	[368,287]	[587,272,368]	0	hSpCas9	negative selection	5354728
3179358	3179380	19	-	27760321	HT29	viability after 10 days	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	-0.09730485269748992	[491,383]	[592,343,589]	-1	hSpCas9	negative selection	5354729
3178868	3178890	19	+	27760321	MOLM13	viability	GTTCTGCACTACAACCACTCGG	S1PR4	ENSG00000125910	-0.15742011531752706	[390,372]	[179,204]	-1	hSpCas9	negative selection	5438188
3179007	3179029	19	-	27760321	MOLM13	viability	CGTCGCGACCGCATGTGGCTGG	S1PR4	ENSG00000125910	-0.6754550844998901	[681,661]	[299,184]	-4	hSpCas9	negative selection	5438189
3179072	3179094	19	+	27760321	MOLM13	viability	CTCACGGGCGCGGCCTACCTGG	S1PR4	ENSG00000125910	-0.039216749219209604	[523,438]	[305,226]	0	hSpCas9	negative selection	5438190
3179268	3179290	19	-	27760321	MOLM13	viability	ATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.6963511566095213	[470,368]	[282,27]	-4	hSpCas9	negative selection	5438191
3179358	3179380	19	-	27760321	MOLM13	viability	AGGCTGGAGCAGCGGTCAAAGG	S1PR4	ENSG00000125910	-0.1245469906549003	[594,491]	[299,262]	-1	hSpCas9	negative selection	5438192
3178765	3178788	19	+	27661255	K562	viability	GGGCCTCAGTCAGCCCCCGGGGG	S1PR4	ENSG00000125910	-0.016375121699051004	[803,962]	[735,660]	0	dCas9-KRAB	negative selection	5509163
3178784	3178807	19	+	27661255	K562	viability	GGGGAGGCCATGAACGCCACGGG	S1PR4	ENSG00000125910	0.2426660310502221	[1130,1218]	[1162,1062]	7	dCas9-KRAB	negative selection	5509164
3178795	3178818	19	+	27661255	K562	viability	GAACGCCACGGGGACCCCGGTGG	S1PR4	ENSG00000125910	-0.22503925991358725	[727,777]	[513,513]	-6	dCas9-KRAB	negative selection	5509165
3178778	3178801	19	-	27661255	K562	viability	GCGTTCATGGCCTCCCCCGGGGG	S1PR4	ENSG00000125910	0.06671639241311147	[783,979]	[789,687]	2	dCas9-KRAB	negative selection	5509166
3179139	3179162	19	-	27661255	K562	viability	GCCCTCCCGTAGGAACCACTGGG	S1PR4	ENSG00000125910	-0.03662279630260401	[1141,1069]	[938,796]	-1	dCas9-KRAB	negative selection	5509167
3179272	3179295	19	-	27661255	K562	viability	GGCCGATGAAGCCGTAGACGCGG	S1PR4	ENSG00000125910	0.44074330675620255	[102,152]	[153,123]	9	dCas9-KRAB	negative selection	5509168
3179268	3179291	19	-	27260156	BXPC3	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.21112602078334008	[167]	[99,121,141,262]	-5	hSpCas9	negative selection	5568692
3179261	3179284	19	+	27260156	BXPC3	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.7069459323089247	[244]	[301,366,516,512]	9	hSpCas9	negative selection	5568693
3179068	3179091	19	-	27260156	BXPC3	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.1184788617686987	[142]	[186,125,128,210]	2	hSpCas9	negative selection	5568694
3179814	3179837	19	-	27260156	BXPC3	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.04493921029096937	[199]	[155,147,292,284]	1	hSpCas9	negative selection	5632946
3179683	3179706	19	-	27260156	BXPC3	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.070751969022668	[654]	[632,574,748,963]	1	hSpCas9	negative selection	5632947
3179861	3179884	19	-	27260156	BXPC3	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.1003889066561392	[318]	[263,302,279,412]	-2	hSpCas9	negative selection	5632948
3179268	3179291	19	-	27260156	A673	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.14197530266556946	[167]	[263,224,211,191]	3	hSpCas9	negative selection	5689943
3179261	3179284	19	+	27260156	A673	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.4600342438828516	[244]	[499,340,365,424]	9	hSpCas9	negative selection	5689944
3179068	3179091	19	-	27260156	A673	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.2689016693194337	[142]	[152,104,107,209]	-6	hSpCas9	negative selection	5689945
3179814	3179837	19	-	27260156	A673	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.016422071947334693	[199]	[210,226,272,234]	0	hSpCas9	negative selection	5754197
3179683	3179706	19	-	27260156	A673	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.11599341298264154	[654]	[781,773,834,1019]	2	hSpCas9	negative selection	5754198
3179861	3179884	19	-	27260156	A673	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.2047598793271007	[318]	[271,430,307,306]	-5	hSpCas9	negative selection	5754199
3179268	3179291	19	-	27260156	A375	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.26773477073799046	[167]	[82,231,86,247]	-4	hSpCas9	negative selection	5811194
3179261	3179284	19	+	27260156	A375	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.5262549493963387	[244]	[328,767,225,376]	7	hSpCas9	negative selection	5811195
3179068	3179091	19	-	27260156	A375	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.36418573537459453	[142]	[175,153,50,139]	-5	hSpCas9	negative selection	5811196
3179814	3179837	19	-	27260156	A375	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.18043463001876936	[199]	[194,207,270,155]	-3	hSpCas9	negative selection	5875448
3179683	3179706	19	-	27260156	A375	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.3357459443060721	[654]	[617,539,627,624]	-5	hSpCas9	negative selection	5875449
3179861	3179884	19	-	27260156	A375	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.5375595344037666	[318]	[138,298,254,328]	-6	hSpCas9	negative selection	5875450
3179268	3179291	19	-	27260156	COLO741	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.204638985895635	[167]	[200,149,206]	-4	hSpCas9	negative selection	5932445
3179261	3179284	19	+	27260156	COLO741	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.43650750583153974	[244]	[321,507,430]	8	hSpCas9	negative selection	5932446
3179068	3179091	19	-	27260156	COLO741	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.34838023280883257	[142]	[208,359,133]	7	hSpCas9	negative selection	5932447
3179814	3179837	19	-	27260156	COLO741	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.7414708054412891	[199]	[350,308,600]	9	hSpCas9	negative selection	5996699
3179683	3179706	19	-	27260156	COLO741	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.15948303762171334	[654]	[752,624,859]	-3	hSpCas9	negative selection	5996700
3179861	3179884	19	-	27260156	COLO741	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.5840558686104654	[318]	[312,212,290]	-8	hSpCas9	negative selection	5996701
3179268	3179291	19	-	27260156	CAL120	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.6573271391846014	[167]	[87,119,181]	-7	hSpCas9	negative selection	6053696
3179261	3179284	19	+	27260156	CAL120	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	1.0234861932505617	[244]	[535,443,861]	9	hSpCas9	negative selection	6053697
3179068	3179091	19	-	27260156	CAL120	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.18954374256474127	[142]	[117,113,228]	-3	hSpCas9	negative selection	6053698
3179814	3179837	19	-	27260156	CAL120	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.43385117907345405	[199]	[239,134,185]	-6	hSpCas9	negative selection	6117950
3179683	3179706	19	-	27260156	CAL120	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.04002218741712027	[654]	[874,681,959]	0	hSpCas9	negative selection	6117951
3179861	3179884	19	-	27260156	CAL120	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.4129537753252186	[318]	[247,296,340]	-5	hSpCas9	negative selection	6117952
3179268	3179291	19	-	27260156	CADOES1	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.15316503495445222	[167]	[167,222,85,82]	-3	hSpCas9	negative selection	6174947
3179261	3179284	19	+	27260156	CADOES1	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.4542341933560862	[244]	[378,287,282,297]	7	hSpCas9	negative selection	6174948
3179068	3179091	19	-	27260156	CADOES1	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.40399259353331773	[142]	[60,115,103,121]	-6	hSpCas9	negative selection	6174949
3179814	3179837	19	-	27260156	CADOES1	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.1633879793838322	[199]	[196,216,218,199]	3	hSpCas9	negative selection	6239201
3179683	3179706	19	-	27260156	CADOES1	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.0441638000921904	[654]	[659,621,469,611]	0	hSpCas9	negative selection	6239202
3179861	3179884	19	-	27260156	CADOES1	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.8328914155786981	[318]	[155,189,212,104]	-9	hSpCas9	negative selection	6239203
3179268	3179291	19	-	27260156	EWS502	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.12900167896186066	[167]	[146,200,204,232]	2	hSpCas9	negative selection	6296198
3179261	3179284	19	+	27260156	EWS502	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.5809656109510017	[244]	[282,381,382,525]	8	hSpCas9	negative selection	6296199
3179068	3179091	19	-	27260156	EWS502	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.01808512605943946	[142]	[89,163,234,113]	0	hSpCas9	negative selection	6296200
3179814	3179837	19	-	27260156	EWS502	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.17290382610693156	[199]	[145,223,174,210]	-3	hSpCas9	negative selection	6360452
3179683	3179706	19	-	27260156	EWS502	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.09078121838968445	[654]	[667,889,651,743]	1	hSpCas9	negative selection	6360453
3179861	3179884	19	-	27260156	EWS502	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.6285779101783905	[318]	[204,184,268,217]	-7	hSpCas9	negative selection	6360454
3179268	3179291	19	-	27260156	EW8	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.04243890405792983	[167]	[197,81,140,112]	-1	hSpCas9	negative selection	6417449
3179261	3179284	19	+	27260156	EW8	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.34208900228309336	[244]	[217,276,223,287]	6	hSpCas9	negative selection	6417450
3179068	3179091	19	-	27260156	EW8	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.07911237955231565	[142]	[188,46,75,191]	1	hSpCas9	negative selection	6417451
3179814	3179837	19	-	27260156	EW8	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.20239815848047882	[199]	[193,114,109,154]	-4	hSpCas9	negative selection	6481703
3179683	3179706	19	-	27260156	EW8	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.08476795744968335	[654]	[589,603,463,611]	1	hSpCas9	negative selection	6481704
3179861	3179884	19	-	27260156	EW8	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.5748938704622185	[318]	[106,221,146,214]	-8	hSpCas9	negative selection	6481705
3179268	3179291	19	-	27260156	CORL105	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.0357915631668182	[167]	[242,244,119,148]	0	hSpCas9	negative selection	6538700
3179261	3179284	19	+	27260156	CORL105	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.15654515534788604	[244]	[272,289,348,369]	3	hSpCas9	negative selection	6538701
3179068	3179091	19	-	27260156	CORL105	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.08273552158326658	[142]	[169,236,227,80]	1	hSpCas9	negative selection	6538702
3179814	3179837	19	-	27260156	CORL105	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.2801597033597192	[199]	[264,300,351,228]	5	hSpCas9	negative selection	6602954
3179683	3179706	19	-	27260156	CORL105	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.21284914201885963	[654]	[732,593,573,734]	-4	hSpCas9	negative selection	6602955
3179861	3179884	19	-	27260156	CORL105	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.5725940063779625	[318]	[231,278,299,199]	-8	hSpCas9	negative selection	6602956
3179268	3179291	19	-	27260156	HS294T	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.33505848718815434	[167]	[83,41,153,41]	4	hSpCas9	negative selection	6659951
3179261	3179284	19	+	27260156	HS294T	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	1.1155495616128783	[244]	[105,223,135,394]	9	hSpCas9	negative selection	6659952
3179068	3179091	19	-	27260156	HS294T	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.1007177238111363	[142]	[47,65,44,45]	-1	hSpCas9	negative selection	6659953
3179814	3179837	19	-	27260156	HS294T	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.15300785825906194	[199]	[33,88,66,94]	-2	hSpCas9	negative selection	6724205
3179683	3179706	19	-	27260156	HS294T	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.04162363867374341	[654]	[248,303,214,275]	0	hSpCas9	negative selection	6724206
3179861	3179884	19	-	27260156	HS294T	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.20911245503783982	[318]	[112,44,157,112]	-3	hSpCas9	negative selection	6724207
3179268	3179291	19	-	27260156	HCC44	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.08517088908831205	[167]	[181,325,200,79]	1	hSpCas9	negative selection	6781202
3179261	3179284	19	+	27260156	HCC44	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.725288968413387	[244]	[591,325,543,413]	9	hSpCas9	negative selection	6781203
3179068	3179091	19	-	27260156	HCC44	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.3503845957421132	[142]	[270,151,267,157]	6	hSpCas9	negative selection	6781204
3179814	3179837	19	-	27260156	HCC44	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.21457433158108463	[199]	[125,183,239,229]	-4	hSpCas9	negative selection	6845456
3179683	3179706	19	-	27260156	HCC44	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.1727253300291225	[654]	[1116,499,960,849]	2	hSpCas9	negative selection	6845457
3179861	3179884	19	-	27260156	HCC44	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.04025619905969802	[318]	[306,276,289,516]	0	hSpCas9	negative selection	6845458
3179268	3179291	19	-	27260156	G402	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.35492356101558564	[167]	[255,445,231,129]	4	hSpCas9	negative selection	6902453
3179261	3179284	19	+	27260156	G402	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.8046921282943537	[244]	[326,650,373,704]	8	hSpCas9	negative selection	6902454
3179068	3179091	19	-	27260156	G402	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.48544626975545846	[142]	[70,193,139,90]	-6	hSpCas9	negative selection	6902455
3179814	3179837	19	-	27260156	G402	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.19034872638804434	[199]	[176,99,431,373]	2	hSpCas9	negative selection	6966707
3179683	3179706	19	-	27260156	G402	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.5493291573032304	[654]	[415,513,689,541]	-6	hSpCas9	negative selection	6966708
3179861	3179884	19	-	27260156	G402	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.9719052664436573	[318]	[84,386,167,149]	-8	hSpCas9	negative selection	6966709
3179268	3179291	19	-	27260156	L33	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.37109981708633377	[167]	[148,52,66,133]	-7	hSpCas9	negative selection	7023704
3179261	3179284	19	+	27260156	L33	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.422507885746229	[244]	[261,111,275,340]	8	hSpCas9	negative selection	7023705
3179068	3179091	19	-	27260156	L33	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.12045596340442732	[142]	[194,75,69,128]	2	hSpCas9	negative selection	7023706
3179814	3179837	19	-	27260156	L33	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.16772410769036195	[199]	[163,92,158,255]	3	hSpCas9	negative selection	7087958
3179683	3179706	19	-	27260156	L33	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.05091107606992695	[654]	[608,227,479,785]	1	hSpCas9	negative selection	7087959
3179861	3179884	19	-	27260156	L33	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.02145906828239441	[318]	[397,135,213,185]	0	hSpCas9	negative selection	7087960
3179268	3179291	19	-	27260156	K562	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.0665137453993645	[167]	[268,127,204,42]	0	hSpCas9	negative selection	7144955
3179261	3179284	19	+	27260156	K562	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	1.0458346240385823	[244]	[523,544,354,387]	9	hSpCas9	negative selection	7144956
3179068	3179091	19	-	27260156	K562	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.09542387634928495	[142]	[135,63,152,119]	-1	hSpCas9	negative selection	7144957
3179814	3179837	19	-	27260156	K562	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.15640016344853191	[199]	[161,320,58,108]	-2	hSpCas9	negative selection	7209209
3179683	3179706	19	-	27260156	K562	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.22428453261110487	[654]	[751,393,250,594]	-3	hSpCas9	negative selection	7209210
3179861	3179884	19	-	27260156	K562	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.6853439421005697	[318]	[181,236,195,100]	-7	hSpCas9	negative selection	7209211
3179268	3179291	19	-	27260156	HT29	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.1667125552624762	[167]	[66,189,231,223]	-3	hSpCas9	negative selection	7266206
3179261	3179284	19	+	27260156	HT29	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.37770021112134855	[244]	[470,401,339,344]	7	hSpCas9	negative selection	7266207
3179068	3179091	19	-	27260156	HT29	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.2968533892496328	[142]	[239,275,228,125]	6	hSpCas9	negative selection	7266208
3179814	3179837	19	-	27260156	HT29	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.106287486403007	[199]	[286,208,182,225]	-2	hSpCas9	negative selection	7330460
3179683	3179706	19	-	27260156	HT29	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.042322423412527566	[654]	[777,804,944,749]	0	hSpCas9	negative selection	7330461
3179861	3179884	19	-	27260156	HT29	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.25129215072930444	[318]	[344,224,481,250]	-5	hSpCas9	negative selection	7330462
3179268	3179291	19	-	27260156	MHHES1	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.180748609275996	[167]	[294,146,200,212]	3	hSpCas9	negative selection	7387457
3179261	3179284	19	+	27260156	MHHES1	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.7362107987250556	[244]	[416,482,555,386]	9	hSpCas9	negative selection	7387458
3179068	3179091	19	-	27260156	MHHES1	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.3564193644620446	[142]	[250,329,196,87]	6	hSpCas9	negative selection	7387459
3179814	3179837	19	-	27260156	MHHES1	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.0030235936572164945	[199]	[274,151,277,194]	0	hSpCas9	negative selection	7451711
3179683	3179706	19	-	27260156	MHHES1	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.07649053985755705	[654]	[711,859,700,811]	1	hSpCas9	negative selection	7451712
3179861	3179884	19	-	27260156	MHHES1	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.633404631611263	[318]	[246,256,304,138]	-8	hSpCas9	negative selection	7451713
3179268	3179291	19	-	27260156	MEWO	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.13442354382260224	[167]	[109,165,146]	-3	hSpCas9	negative selection	7508708
3179261	3179284	19	+	27260156	MEWO	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.3742567970446935	[244]	[428,252,234]	7	hSpCas9	negative selection	7508709
3179068	3179091	19	-	27260156	MEWO	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.20750532090331308	[142]	[135,118,204]	4	hSpCas9	negative selection	7508710
3179814	3179837	19	-	27260156	MEWO	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.17630514122799168	[199]	[176,152,168]	-4	hSpCas9	negative selection	7572962
3179683	3179706	19	-	27260156	MEWO	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.10302733991968227	[654]	[792,496,464]	-2	hSpCas9	negative selection	7572963
3179861	3179884	19	-	27260156	MEWO	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.10054163915742087	[318]	[334,272,237]	-2	hSpCas9	negative selection	7572964
3179268	3179291	19	-	27260156	LNCAPCLONEFGC	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.10687694969847272	[167]	[202,91,132,137]	-2	hSpCas9	negative selection	7629959
3179261	3179284	19	+	27260156	LNCAPCLONEFGC	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.24460987829465164	[244]	[210,311,300,230]	4	hSpCas9	negative selection	7629960
3179068	3179091	19	-	27260156	LNCAPCLONEFGC	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.28014741171142266	[142]	[193,87,197,158]	4	hSpCas9	negative selection	7629961
3179814	3179837	19	-	27260156	LNCAPCLONEFGC	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.12431786312988846	[199]	[94,163,251,167]	-2	hSpCas9	negative selection	7694213
3179683	3179706	19	-	27260156	LNCAPCLONEFGC	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.08231683684966817	[654]	[710,490,629,687]	1	hSpCas9	negative selection	7694214
3179861	3179884	19	-	27260156	LNCAPCLONEFGC	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.2981538921147263	[318]	[247,176,224,291]	-5	hSpCas9	negative selection	7694215
3179268	3179291	19	-	27260156	PANC0327	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.5015663567850261	[167]	[289,114,245,212]	7	hSpCas9	negative selection	7751210
3179261	3179284	19	+	27260156	PANC0327	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.7171503209937753	[244]	[751,281,232,205]	9	hSpCas9	negative selection	7751211
3179068	3179091	19	-	27260156	PANC0327	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.8025912679017005	[142]	[369,254,149,118]	9	hSpCas9	negative selection	7751212
3179814	3179837	19	-	27260156	PANC0327	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.2665415820534226	[199]	[288,266,142,154]	4	hSpCas9	negative selection	7815464
3179683	3179706	19	-	27260156	PANC0327	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.15792397731163832	[654]	[752,537,544,782]	2	hSpCas9	negative selection	7815465
3179861	3179884	19	-	27260156	PANC0327	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.8306460923045612	[318]	[150,148,192,144]	-8	hSpCas9	negative selection	7815466
3179268	3179291	19	-	27260156	NCIH2009	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.2106807060172735	[167]	[177,215,208]	-3	hSpCas9	negative selection	7872461
3179261	3179284	19	+	27260156	NCIH2009	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.6963434550588428	[244]	[720,550,423]	8	hSpCas9	negative selection	7872462
3179068	3179091	19	-	27260156	NCIH2009	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.3144776097957984	[142]	[250,217,276]	4	hSpCas9	negative selection	7872463
3179814	3179837	19	-	27260156	NCIH2009	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.34936485338007683	[199]	[501,203,392]	5	hSpCas9	negative selection	7936715
3179683	3179706	19	-	27260156	NCIH2009	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.1860363905516607	[654]	[860,808,752]	-3	hSpCas9	negative selection	7936716
3179861	3179884	19	-	27260156	NCIH2009	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.19725294290709194	[318]	[520,371,298]	-3	hSpCas9	negative selection	7936717
3179268	3179291	19	-	27260156	NCIH1373	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.20014148205675397	[167]	[73,158,250,97]	2	hSpCas9	negative selection	7993712
3179261	3179284	19	+	27260156	NCIH1373	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.21893720001270922	[244]	[490,323,202,74]	2	hSpCas9	negative selection	7993713
3179068	3179091	19	-	27260156	NCIH1373	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.7470952268306907	[142]	[227,99,413,90]	7	hSpCas9	negative selection	7993714
3179814	3179837	19	-	27260156	NCIH1373	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.3102441095115265	[199]	[241,91,76,89]	-3	hSpCas9	negative selection	8057966
3179683	3179706	19	-	27260156	NCIH1373	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.07955603268372985	[654]	[1127,455,471,216]	-1	hSpCas9	negative selection	8057967
3179861	3179884	19	-	27260156	NCIH1373	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-1.0806178495212335	[318]	[160,242,109,39]	-8	hSpCas9	negative selection	8057968
3179268	3179291	19	-	27260156	PATU8902	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.4812094460020546	[167]	[154,388,31,123]	-5	hSpCas9	negative selection	8114963
3179261	3179284	19	+	27260156	PATU8902	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	1.2862495992765965	[244]	[652,1461,585,669]	9	hSpCas9	negative selection	8114964
3179068	3179091	19	-	27260156	PATU8902	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.1931954093644288	[142]	[167,164,69,590]	2	hSpCas9	negative selection	8114965
3179814	3179837	19	-	27260156	PATU8902	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.24810472129400063	[199]	[306,241,229,146]	-3	hSpCas9	negative selection	8179217
3179683	3179706	19	-	27260156	PATU8902	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.22943139569142035	[654]	[1333,567,1320,962]	2	hSpCas9	negative selection	8179218
3179861	3179884	19	-	27260156	PATU8902	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.028483764377808085	[318]	[439,459,431,403]	0	hSpCas9	negative selection	8179219
3179268	3179291	19	-	27260156	PANC1	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.5012999281835866	[167]	[72,194,351,196]	7	hSpCas9	negative selection	8236214
3179261	3179284	19	+	27260156	PANC1	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.0580309010007789	[244]	[182,294,232,183]	0	hSpCas9	negative selection	8236215
3179068	3179091	19	-	27260156	PANC1	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.2868370942414715	[142]	[161,216,121,114]	4	hSpCas9	negative selection	8236216
3179814	3179837	19	-	27260156	PANC1	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.14985016978060184	[199]	[183,356,130,130]	2	hSpCas9	negative selection	8300468
3179683	3179706	19	-	27260156	PANC1	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.012216568548447382	[654]	[568,736,550,423]	0	hSpCas9	negative selection	8300469
3179861	3179884	19	-	27260156	PANC1	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.7997728842369906	[318]	[182,212,128,118]	-8	hSpCas9	negative selection	8300470
3179268	3179291	19	-	27260156	PANC0813	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.35235905316141825	[167]	[432,210,187,194]	5	hSpCas9	negative selection	8357465
3179261	3179284	19	+	27260156	PANC0813	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.6462595165959892	[244]	[387,576,486,348]	8	hSpCas9	negative selection	8357466
3179068	3179091	19	-	27260156	PANC0813	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.04741244667728406	[142]	[154,246,201,92]	0	hSpCas9	negative selection	8357467
3179814	3179837	19	-	27260156	PANC0813	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.33508734328344647	[199]	[348,251,175,405]	5	hSpCas9	negative selection	8421719
3179683	3179706	19	-	27260156	PANC0813	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.1262508335520407	[654]	[1021,711,845,796]	2	hSpCas9	negative selection	8421720
3179861	3179884	19	-	27260156	PANC0813	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.2551742709847481	[318]	[537,256,262,222]	-4	hSpCas9	negative selection	8421721
3179268	3179291	19	-	27260156	RDES	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.19479708931681738	[167]	[251,152,233,240]	3	hSpCas9	negative selection	8478716
3179261	3179284	19	+	27260156	RDES	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.6814102002058039	[244]	[337,377,501,638]	9	hSpCas9	negative selection	8478717
3179068	3179091	19	-	27260156	RDES	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.27999955565712265	[142]	[114,250,192,255]	4	hSpCas9	negative selection	8478718
3179814	3179837	19	-	27260156	RDES	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.1242753174350586	[199]	[182,202,288,357]	2	hSpCas9	negative selection	8542970
3179683	3179706	19	-	27260156	RDES	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.1531033187679146	[654]	[458,761,831,682]	-3	hSpCas9	negative selection	8542971
3179861	3179884	19	-	27260156	RDES	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.3848531657602021	[318]	[228,276,320,304]	-6	hSpCas9	negative selection	8542972
3179268	3179291	19	-	27260156	PC3	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.07559078145320441	[167]	[153,197,288,89]	1	hSpCas9	negative selection	8599967
3179261	3179284	19	+	27260156	PC3	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.6089803584249083	[244]	[177,379,433,586]	9	hSpCas9	negative selection	8599968
3179068	3179091	19	-	27260156	PC3	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.40247246362338474	[142]	[115,249,284,147]	8	hSpCas9	negative selection	8599969
3179814	3179837	19	-	27260156	PC3	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.3520517270559822	[199]	[110,98,191,246]	-7	hSpCas9	negative selection	8664221
3179683	3179706	19	-	27260156	PC3	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.03905013289385706	[654]	[527,646,811,736]	0	hSpCas9	negative selection	8664222
3179861	3179884	19	-	27260156	PC3	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.5379884156926734	[318]	[102,234,262,329]	-8	hSpCas9	negative selection	8664223
3179268	3179291	19	-	27260156	PATU8988T	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.803421690299978	[167]	[396,283,90,370]	9	hSpCas9	negative selection	8721218
3179261	3179284	19	+	27260156	PATU8988T	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.8966915786498106	[244]	[340,494,415,522]	9	hSpCas9	negative selection	8721219
3179068	3179091	19	-	27260156	PATU8988T	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.46168427495414655	[142]	[37,58,228,66]	-6	hSpCas9	negative selection	8721220
3179814	3179837	19	-	27260156	PATU8988T	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.10907883700444088	[199]	[136,193,145,246]	-2	hSpCas9	negative selection	8785472
3179683	3179706	19	-	27260156	PATU8988T	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.14619203967067917	[654]	[671,752,590,799]	2	hSpCas9	negative selection	8785473
3179861	3179884	19	-	27260156	PATU8988T	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.31488115363392544	[318]	[197,182,272,337]	-5	hSpCas9	negative selection	8785474
3179268	3179291	19	-	27260156	T47D	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.060997351989599435	[167]	[217,193,161,175]	-1	hSpCas9	negative selection	8842469
3179261	3179284	19	+	27260156	T47D	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.3460877742182431	[244]	[386,353,351,358]	7	hSpCas9	negative selection	8842470
3179068	3179091	19	-	27260156	T47D	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.018865069333767304	[142]	[166,142,174,192]	0	hSpCas9	negative selection	8842471
3179814	3179837	19	-	27260156	T47D	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.025625047205875662	[199]	[210,235,226,275]	0	hSpCas9	negative selection	8906723
3179683	3179706	19	-	27260156	T47D	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.009132880018099587	[654]	[719,700,714,906]	0	hSpCas9	negative selection	8906724
3179861	3179884	19	-	27260156	T47D	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.3402489880301681	[318]	[298,282,257,336]	-6	hSpCas9	negative selection	8906725
3179268	3179291	19	-	27260156	SU8686	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.0036211969323178828	[167]	[95,62,292,249]	0	hSpCas9	negative selection	8963720
3179261	3179284	19	+	27260156	SU8686	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.8179167930648713	[244]	[397,357,505,468]	9	hSpCas9	negative selection	8963721
3179068	3179091	19	-	27260156	SU8686	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.23814790606590663	[142]	[118,58,191,119]	-4	hSpCas9	negative selection	8963722
3179814	3179837	19	-	27260156	SU8686	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.1616672101704455	[199]	[122,169,145,293]	-3	hSpCas9	negative selection	9027974
3179683	3179706	19	-	27260156	SU8686	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.007092171857415452	[654]	[552,599,719,771]	0	hSpCas9	negative selection	9027975
3179861	3179884	19	-	27260156	SU8686	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.637973723591391	[318]	[176,191,269,173]	-7	hSpCas9	negative selection	9027976
3179268	3179291	19	-	27260156	SKES1	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.222657818308595	[167]	[149,208,94,129]	-5	hSpCas9	negative selection	9084971
3179261	3179284	19	+	27260156	SKES1	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.34014454302091235	[244]	[256,554,180,269]	7	hSpCas9	negative selection	9084972
3179068	3179091	19	-	27260156	SKES1	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.09972078122591821	[142]	[103,169,190,140]	2	hSpCas9	negative selection	9084973
3179814	3179837	19	-	27260156	SKES1	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.10659904871306702	[199]	[257,145,210,236]	2	hSpCas9	negative selection	9149225
3179683	3179706	19	-	27260156	SKES1	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.14909811460060252	[654]	[982,587,581,754]	3	hSpCas9	negative selection	9149226
3179861	3179884	19	-	27260156	SKES1	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.09461825103328991	[318]	[393,377,248,202]	-2	hSpCas9	negative selection	9149227
3179268	3179291	19	-	27260156	TOV112D	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.1290740995858477	[167]	[149,208,267,113]	2	hSpCas9	negative selection	9206222
3179261	3179284	19	+	27260156	TOV112D	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	-0.008708989659465649	[244]	[241,375,197,192]	0	hSpCas9	negative selection	9206223
3179068	3179091	19	-	27260156	TOV112D	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	0.7296361308464513	[142]	[200,223,273,243]	9	hSpCas9	negative selection	9206224
3179814	3179837	19	-	27260156	TOV112D	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.011714581973066851	[199]	[128,132,235,283]	0	hSpCas9	negative selection	9270476
3179683	3179706	19	-	27260156	TOV112D	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.1134429245218771	[654]	[813,832,748,486]	2	hSpCas9	negative selection	9270477
3179861	3179884	19	-	27260156	TOV112D	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.6635404796570369	[318]	[324,180,220,87]	-8	hSpCas9	negative selection	9270478
3179268	3179291	19	-	27260156	TC71	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	-0.2723221003866334	[167]	[153,162,119,160]	-6	hSpCas9	negative selection	9327473
3179261	3179284	19	+	27260156	TC71	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.638887583516462	[244]	[355,481,345,457]	9	hSpCas9	negative selection	9327474
3179068	3179091	19	-	27260156	TC71	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.7074810267460676	[142]	[50,114,112,96]	-9	hSpCas9	negative selection	9327475
3179814	3179837	19	-	27260156	TC71	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	0.16159549418084018	[199]	[199,314,197,248]	4	hSpCas9	negative selection	9391727
3179683	3179706	19	-	27260156	TC71	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	-0.06488628916571204	[654]	[667,617,687,712]	-2	hSpCas9	negative selection	9391728
3179861	3179884	19	-	27260156	TC71	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.31784466388597044	[318]	[224,324,327,214]	-7	hSpCas9	negative selection	9391729
3179268	3179291	19	-	27260156	TC32	viability	GATGAAGCCGTAGACGCGGCTGG	S1PR4	ENSG00000125910	0.08515141744293264	[167]	[122,87,286,222]	1	hSpCas9	negative selection	9448724
3179261	3179284	19	+	27260156	TC32	viability	ACCAAGACCAGCCGCGTCTACGG	S1PR4	ENSG00000125910	0.5303006318401593	[244]	[245,172,585,428]	8	hSpCas9	negative selection	9448725
3179068	3179091	19	-	27260156	TC32	viability	GGTAGGCCGCGCCCGTGAGCAGG	S1PR4	ENSG00000125910	-0.07864668273105657	[142]	[199,37,132,157]	-1	hSpCas9	negative selection	9448726
3179814	3179837	19	-	27260156	TC32	viability	AGCTCCGGAGTGAGCCTCGACGG	S1PR4	ENSG00000125910	-0.6221348096866919	[199]	[130,75,134,159]	-8	hSpCas9	negative selection	9512978
3179683	3179706	19	-	27260156	TC32	viability	TGGGGTTGACCGCCGAGTTGAGG	S1PR4	ENSG00000125910	0.1953395963236667	[654]	[573,543,898,881]	3	hSpCas9	negative selection	9512979
3179861	3179884	19	-	27260156	TC32	viability	GAGCCGCGAAAGCTGTCCCTTGG	S1PR4	ENSG00000125910	-0.26668940308556677	[318]	[191,258,263,272]	-5	hSpCas9	negative selection	9512980
3178876	3178899	19	+	27869803	HPAFII	viability after 27 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	0.5637395578721459	[176]	[250,42,NaN]	4	hSpCas9	negative selection	9566926
3179137	3179160	19	+	27869803	HPAFII	viability after 27 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-0.600984593479569	[731]	[304,210,NaN]	-4	hSpCas9	negative selection	9566927
3179221	3179244	19	+	27869803	HPAFII	viability after 27 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	1.1934632225185275	[114]	[134,140,NaN]	8	hSpCas9	negative selection	9566928
3179530	3179553	19	-	27869803	HPAFII	viability after 27 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.08829362497270027	[215]	[54,149,NaN]	0	hSpCas9	negative selection	9566929
3179668	3179691	19	-	27869803	HPAFII	viability after 27 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	0.16329425420998533	[62]	[65,12,NaN]	1	hSpCas9	negative selection	9566930
3179707	3179730	19	+	27869803	HPAFII	viability after 27 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.563371516418238	[468]	[317,402,NaN]	4	hSpCas9	negative selection	9566931
3178876	3178899	19	+	27869803	HPAFII	viability after 15 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	1.2997540254335895	[176]	[619,373,NaN]	9	hSpCas9	negative selection	9649375
3179137	3179160	19	+	27869803	HPAFII	viability after 15 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-0.04495691416197811	[731]	[1097,553,NaN]	0	hSpCas9	negative selection	9649376
3179221	3179244	19	+	27869803	HPAFII	viability after 15 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	0.6167780027211415	[114]	[273,136,NaN]	7	hSpCas9	negative selection	9649377
3179530	3179553	19	-	27869803	HPAFII	viability after 15 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.2654013734571339	[215]	[202,186,NaN]	-3	hSpCas9	negative selection	9649378
3179668	3179691	19	-	27869803	HPAFII	viability after 15 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	-0.09630743893346172	[62]	[87,47,NaN]	-1	hSpCas9	negative selection	9649379
3179707	3179730	19	+	27869803	HPAFII	viability after 15 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.6153423676614771	[468]	[728,798,NaN]	7	hSpCas9	negative selection	9649380
3178876	3178899	19	+	27869803	ASPC1	viability after 36 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	0.20365737595099362	[721]	[539,327,81]	2	hSpCas9	negative selection	9731824
3179137	3179160	19	+	27869803	ASPC1	viability after 36 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.2968761719740014	[1751]	[897,465,866]	3	hSpCas9	negative selection	9731825
3179221	3179244	19	+	27869803	ASPC1	viability after 36 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	1.4620473303618433	[297]	[158,229,417]	9	hSpCas9	negative selection	9731826
3179530	3179553	19	-	27869803	ASPC1	viability after 36 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.23423712025806231	[718]	[350,395,172]	2	hSpCas9	negative selection	9731827
3179668	3179691	19	-	27869803	ASPC1	viability after 36 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	0.4405013031553022	[174]	[84,167,12]	4	hSpCas9	negative selection	9731828
3179707	3179730	19	+	27869803	ASPC1	viability after 36 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.4469017713409469	[1095]	[406,332,745]	4	hSpCas9	negative selection	9731829
3178876	3178899	19	+	27869803	PATU8988S	viability after 35 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	-0.41878201880710775	[721]	[227,206,NaN]	-4	hSpCas9	negative selection	9814273
3179137	3179160	19	+	27869803	PATU8988S	viability after 35 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.1061519656651353	[1555]	[686,661,NaN]	1	hSpCas9	negative selection	9814274
3179221	3179244	19	+	27869803	PATU8988S	viability after 35 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	1.6879968652159183	[221]	[326,248,NaN]	9	hSpCas9	negative selection	9814275
3179530	3179553	19	-	27869803	PATU8988S	viability after 35 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.6675737521893634	[589]	[569,183,NaN]	7	hSpCas9	negative selection	9814276
3179668	3179691	19	-	27869803	PATU8988S	viability after 35 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	0.8784648559306139	[130]	[94,98,NaN]	8	hSpCas9	negative selection	9814277
3179707	3179730	19	+	27869803	PATU8988S	viability after 35 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.38730910742011404	[1103]	[608,553,NaN]	4	hSpCas9	negative selection	9814278
3178876	3178899	19	+	27869803	PATU8988S	viability after 31 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	-0.2613526978877076	[721]	[193,298,NaN]	-3	hSpCas9	negative selection	9896722
3179137	3179160	19	+	27869803	PATU8988S	viability after 31 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.10876192604334145	[1555]	[606,747,NaN]	1	hSpCas9	negative selection	9896723
3179221	3179244	19	+	27869803	PATU8988S	viability after 31 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	1.7310670115971214	[221]	[226,378,NaN]	9	hSpCas9	negative selection	9896724
3179530	3179553	19	-	27869803	PATU8988S	viability after 31 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.07664628158791083	[589]	[321,153,NaN]	1	hSpCas9	negative selection	9896725
3179668	3179691	19	-	27869803	PATU8988S	viability after 31 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	0.6859456761140876	[130]	[54,120,NaN]	7	hSpCas9	negative selection	9896726
3179707	3179730	19	+	27869803	PATU8988S	viability after 31 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.2571913158151655	[1103]	[526,524,NaN]	3	hSpCas9	negative selection	9896727
3178876	3178899	19	+	27869803	HPAFII	viability after 35 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	0.6552875194712227	[176]	[150,129,NaN]	4	hSpCas9	negative selection	9979171
3179137	3179160	19	+	27869803	HPAFII	viability after 35 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	0.019247625037302596	[731]	[296,463,NaN]	0	hSpCas9	negative selection	9979172
3179221	3179244	19	+	27869803	HPAFII	viability after 35 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	0.9686379147844862	[114]	[96,132,NaN]	6	hSpCas9	negative selection	9979173
3179530	3179553	19	-	27869803	HPAFII	viability after 35 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.21008192642339277	[215]	[46,215,NaN]	1	hSpCas9	negative selection	9979174
3179668	3179691	19	-	27869803	HPAFII	viability after 35 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	0.16312394055441048	[62]	[46,22,NaN]	1	hSpCas9	negative selection	9979175
3179707	3179730	19	+	27869803	HPAFII	viability after 35 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.24260394463573798	[468]	[215,353,NaN]	1	hSpCas9	negative selection	9979176
3178876	3178899	19	+	27869803	HPAFII	viability after 31 days	CTACAACCACTCGGGCCGGCTGG	S1PR4	ENSG00000125910	0.6538077503272129	[176]	[184,124,NaN]	5	hSpCas9	negative selection	10061620
3179137	3179160	19	+	27869803	HPAFII	viability after 31 days	CGCCCAGTGGTTCCTACGGGAGG	S1PR4	ENSG00000125910	-0.6567935465016471	[731]	[183,343,NaN]	-4	hSpCas9	negative selection	10061621
3179221	3179244	19	+	27869803	HPAFII	viability after 31 days	CTTTGCCACCATGGTGCGGCCGG	S1PR4	ENSG00000125910	1.2520556274047192	[114]	[113,196,NaN]	8	hSpCas9	negative selection	10061622
3179530	3179553	19	-	27869803	HPAFII	viability after 31 days	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.027131585871463776	[215]	[39,204,NaN]	0	hSpCas9	negative selection	10061623
3179668	3179691	19	-	27869803	HPAFII	viability after 31 days	AGTTGAGGACGGCCAGGGCCAGG	S1PR4	ENSG00000125910	0.6695060221171321	[62]	[94,13,NaN]	5	hSpCas9	negative selection	10061624
3179707	3179730	19	+	27869803	HPAFII	viability after 31 days	CATCTACTCCTTCCGCAGCAGGG	S1PR4	ENSG00000125910	0.5696598911247963	[468]	[326,459,NaN]	4	hSpCas9	negative selection	10061625
3179181	3179204	19	-	28162770	P31FUJ	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-1.0522299587725579	[29]	[16]	-6	hSpCas9	negative selection	10229474
3179568	3179591	19	-	28162770	P31FUJ	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	0.12138008947761025	[114]	[146]	1	hSpCas9	negative selection	10229475
3178785	3178808	19	+	28162770	P31FUJ	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.5321777659214242	[305]	[519]	6	hSpCas9	negative selection	10229476
3178822	3178845	19	+	28162770	P31FUJ	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	0.19231907559349581	[498]	[669]	2	hSpCas9	negative selection	10229477
3178978	3179001	19	+	28162770	P31FUJ	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	0.0030107326843910355	[213]	[251]	0	hSpCas9	negative selection	10229478
3179365	3179388	19	-	28162770	P31FUJ	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-1.285913540873941	[82]	[39]	-7	hSpCas9	negative selection	10229479
3179530	3179553	19	-	28162770	P31FUJ	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.19420793653054136	[89]	[120]	2	hSpCas9	negative selection	10229480
3179755	3179778	19	-	28162770	P31FUJ	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	-0.3191430533534253	[240]	[226]	-3	hSpCas9	negative selection	10229481
3179330	3179353	19	-	28162770	P31FUJ	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	-0.002257729929632468	[478]	[561]	0	hSpCas9	negative selection	10229482
3179494	3179517	19	+	28162770	P31FUJ	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	0.35121519634445675	[508]	[762]	4	hSpCas9	negative selection	10229483
3179181	3179204	19	-	28162770	TF1	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10398840
3179568	3179591	19	-	28162770	TF1	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10398841
3178785	3178808	19	+	28162770	TF1	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10398842
3178822	3178845	19	+	28162770	TF1	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	NaN	[NaN]	[428]	1	hSpCas9	negative selection	10398843
3178978	3179001	19	+	28162770	TF1	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10398844
3179365	3179388	19	-	28162770	TF1	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10398845
3179530	3179553	19	-	28162770	TF1	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10398846
3179755	3179778	19	-	28162770	TF1	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10398847
3179330	3179353	19	-	28162770	TF1	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	NaN	[NaN]	[472]	1	hSpCas9	negative selection	10398848
3179494	3179517	19	+	28162770	TF1	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	NaN	[NaN]	[489]	1	hSpCas9	negative selection	10398849
3179181	3179204	19	-	28162770	SKM1	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-2.7288922936305235	[14]	[3]	-9	hSpCas9	negative selection	10568206
3179568	3179591	19	-	28162770	SKM1	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	-1.9215373715729203	[29]	[13]	-8	hSpCas9	negative selection	10568207
3178785	3178808	19	+	28162770	SKM1	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	-0.7631080089684371	[71]	[74]	-5	hSpCas9	negative selection	10568208
3178822	3178845	19	+	28162770	SKM1	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	-0.841237916884923	[150]	[148]	-6	hSpCas9	negative selection	10568209
3178978	3179001	19	+	28162770	SKM1	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	-1.5969351423872322	[76]	[44]	-8	hSpCas9	negative selection	10568210
3179365	3179388	19	-	28162770	SKM1	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-1.4069641987431614	[11]	[7]	-7	hSpCas9	negative selection	10568211
3179530	3179553	19	-	28162770	SKM1	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.5463672554085783	[18]	[22]	-4	hSpCas9	negative selection	10568212
3179755	3179778	19	-	28162770	SKM1	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	-1.8923910259134034	[62]	[29]	-8	hSpCas9	negative selection	10568213
3179330	3179353	19	-	28162770	SKM1	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	-0.4785174597681959	[92]	[117]	-4	hSpCas9	negative selection	10568214
3179494	3179517	19	+	28162770	SKM1	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	-0.8220016980220055	[101]	[101]	-6	hSpCas9	negative selection	10568215
3179181	3179204	19	-	28162770	SKM1	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-2.7288922936305235	[14]	[3]	-9	hSpCas9	negative selection	10737572
3179568	3179591	19	-	28162770	SKM1	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	-1.9215373715729203	[29]	[13]	-8	hSpCas9	negative selection	10737573
3178785	3178808	19	+	28162770	SKM1	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	-0.7631080089684371	[71]	[74]	-5	hSpCas9	negative selection	10737574
3178822	3178845	19	+	28162770	SKM1	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	-0.841237916884923	[150]	[148]	-6	hSpCas9	negative selection	10737575
3178978	3179001	19	+	28162770	SKM1	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	-1.5969351423872322	[76]	[44]	-8	hSpCas9	negative selection	10737576
3179365	3179388	19	-	28162770	SKM1	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-1.4069641987431614	[11]	[7]	-7	hSpCas9	negative selection	10737577
3179530	3179553	19	-	28162770	SKM1	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.5463672554085783	[18]	[22]	-4	hSpCas9	negative selection	10737578
3179755	3179778	19	-	28162770	SKM1	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	-1.8923910259134034	[62]	[29]	-8	hSpCas9	negative selection	10737579
3179330	3179353	19	-	28162770	SKM1	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	-0.4785174597681959	[92]	[117]	-4	hSpCas9	negative selection	10737580
3179494	3179517	19	+	28162770	SKM1	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	-0.8220016980220055	[101]	[101]	-6	hSpCas9	negative selection	10737581
3179181	3179204	19	-	28162770	PL21	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	1.5834682540408258	[45]	[59]	9	hSpCas9	negative selection	10906938
3179568	3179591	19	-	28162770	PL21	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	1.499699896348228	[64]	[79]	9	hSpCas9	negative selection	10906939
3178785	3178808	19	+	28162770	PL21	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.33423251007660304	[307]	[168]	3	hSpCas9	negative selection	10906940
3178822	3178845	19	+	28162770	PL21	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	-0.1863125587908716	[582]	[222]	-1	hSpCas9	negative selection	10906941
3178978	3179001	19	+	28162770	PL21	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	-0.17701800111843435	[212]	[81]	-1	hSpCas9	negative selection	10906942
3179365	3179388	19	-	28162770	PL21	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-2.0014942466803305	[45]	[4]	-8	hSpCas9	negative selection	10906943
3179530	3179553	19	-	28162770	PL21	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.09942066736958788	[31]	[12]	0	hSpCas9	negative selection	10906944
3179755	3179778	19	-	28162770	PL21	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	-0.11213831036432281	[148]	[59]	-1	hSpCas9	negative selection	10906945
3179330	3179353	19	-	28162770	PL21	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	-0.3892687912630281	[324]	[107]	-3	hSpCas9	negative selection	10906946
3179494	3179517	19	+	28162770	PL21	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	-0.07774791943883141	[370]	[152]	0	hSpCas9	negative selection	10906947
3179181	3179204	19	-	28162770	P31FUJ	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-1.0522299587725579	[29]	[16]	-6	hSpCas9	negative selection	11076304
3179568	3179591	19	-	28162770	P31FUJ	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	0.12138008947761025	[114]	[146]	1	hSpCas9	negative selection	11076305
3178785	3178808	19	+	28162770	P31FUJ	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.5321777659214242	[305]	[519]	6	hSpCas9	negative selection	11076306
3178822	3178845	19	+	28162770	P31FUJ	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	0.19231907559349581	[498]	[669]	2	hSpCas9	negative selection	11076307
3178978	3179001	19	+	28162770	P31FUJ	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	0.0030107326843910355	[213]	[251]	0	hSpCas9	negative selection	11076308
3179365	3179388	19	-	28162770	P31FUJ	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-1.285913540873941	[82]	[39]	-7	hSpCas9	negative selection	11076309
3179530	3179553	19	-	28162770	P31FUJ	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.19420793653054136	[89]	[120]	2	hSpCas9	negative selection	11076310
3179755	3179778	19	-	28162770	P31FUJ	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	-0.3191430533534253	[240]	[226]	-3	hSpCas9	negative selection	11076311
3179330	3179353	19	-	28162770	P31FUJ	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	-0.002257729929632468	[478]	[561]	0	hSpCas9	negative selection	11076312
3179494	3179517	19	+	28162770	P31FUJ	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	0.35121519634445675	[508]	[762]	4	hSpCas9	negative selection	11076313
3179181	3179204	19	-	28162770	OCIAML5	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-5.311498189501295	[21]	[0]	-9	hSpCas9	negative selection	11245670
3179568	3179591	19	-	28162770	OCIAML5	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	-0.524012373179793	[46]	[58]	-4	hSpCas9	negative selection	11245671
3178785	3178808	19	+	28162770	OCIAML5	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	1.0926260574569058	[112]	[434]	8	hSpCas9	negative selection	11245672
3178822	3178845	19	+	28162770	OCIAML5	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	-0.5738598534059527	[267]	[324]	-4	hSpCas9	negative selection	11245673
3178978	3179001	19	+	28162770	OCIAML5	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	-0.8375670011688818	[98]	[99]	-5	hSpCas9	negative selection	11245674
3179365	3179388	19	-	28162770	OCIAML5	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	0.14793342913600327	[18]	[37]	1	hSpCas9	negative selection	11245675
3179530	3179553	19	-	28162770	OCIAML5	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.06151867731852989	[42]	[80]	0	hSpCas9	negative selection	11245676
3179755	3179778	19	-	28162770	OCIAML5	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	0.18857541363334895	[69]	[143]	1	hSpCas9	negative selection	11245677
3179330	3179353	19	-	28162770	OCIAML5	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	-0.7929718233415798	[286]	[298]	-5	hSpCas9	negative selection	11245678
3179494	3179517	19	+	28162770	OCIAML5	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	-0.27726393636306235	[189]	[282]	-2	hSpCas9	negative selection	11245679
3179181	3179204	19	-	28162770	EOL1	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-4.075452228429466	[63]	[1]	-9	hSpCas9	negative selection	11415036
3179568	3179591	19	-	28162770	EOL1	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	-0.28304764783783276	[96]	[41]	-2	hSpCas9	negative selection	11415037
3178785	3178808	19	+	28162770	EOL1	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.6385522172934297	[683]	[560]	6	hSpCas9	negative selection	11415038
3178822	3178845	19	+	28162770	EOL1	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	0.04397558680059532	[1065]	[578]	0	hSpCas9	negative selection	11415039
3178978	3179001	19	+	28162770	EOL1	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	-0.19344943782791696	[381]	[175]	-1	hSpCas9	negative selection	11415040
3179365	3179388	19	-	28162770	EOL1	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	0.3551821259003971	[91]	[61]	3	hSpCas9	negative selection	11415041
3179530	3179553	19	-	28162770	EOL1	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.9804010063040519	[75]	[78]	8	hSpCas9	negative selection	11415042
3179755	3179778	19	-	28162770	EOL1	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	0.48550480928090134	[201]	[148]	4	hSpCas9	negative selection	11415043
3179330	3179353	19	-	28162770	EOL1	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	-0.8271931752760697	[457]	[135]	-5	hSpCas9	negative selection	11415044
3179494	3179517	19	+	28162770	EOL1	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	-0.08794317261266249	[463]	[229]	0	hSpCas9	negative selection	11415045
3179181	3179204	19	-	28162770	MOLM13	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-0.6316462920063355	[59]	[27]	-4	hSpCas9	negative selection	11584402
3179568	3179591	19	-	28162770	MOLM13	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	1.1643123127542783	[165]	[268]	8	hSpCas9	negative selection	11584403
3178785	3178808	19	+	28162770	MOLM13	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.6978949869909018	[404]	[474]	5	hSpCas9	negative selection	11584404
3178822	3178845	19	+	28162770	MOLM13	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	0.43000949787348963	[655]	[638]	3	hSpCas9	negative selection	11584405
3178978	3179001	19	+	28162770	MOLM13	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	0.14072463829106918	[275]	[219]	1	hSpCas9	negative selection	11584406
3179365	3179388	19	-	28162770	MOLM13	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-2.9915422370927187	[87]	[7]	-8	hSpCas9	negative selection	11584407
3179530	3179553	19	-	28162770	MOLM13	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.1995352793685503	[80]	[50]	-1	hSpCas9	negative selection	11584408
3179755	3179778	19	-	28162770	MOLM13	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	-2.3021845244335655	[190]	[27]	-8	hSpCas9	negative selection	11584409
3179330	3179353	19	-	28162770	MOLM13	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	0.4901278957209394	[514]	[522]	3	hSpCas9	negative selection	11584410
3179494	3179517	19	+	28162770	MOLM13	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	0.12192227508959841	[468]	[368]	0	hSpCas9	negative selection	11584411
3179181	3179204	19	-	28162770	HEL	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-4.783525922701741	[42]	[0]	-9	hSpCas9	negative selection	11753768
3179568	3179591	19	-	28162770	HEL	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	1.0452853870960037	[86]	[114]	8	hSpCas9	negative selection	11753769
3178785	3178808	19	+	28162770	HEL	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.954891004398842	[384]	[477]	8	hSpCas9	negative selection	11753770
3178822	3178845	19	+	28162770	HEL	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	-0.39033298960529184	[705]	[344]	-3	hSpCas9	negative selection	11753771
3178978	3179001	19	+	28162770	HEL	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	0.6322464581827147	[275]	[273]	5	hSpCas9	negative selection	11753772
3179365	3179388	19	-	28162770	HEL	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-1.7419250182349684	[46]	[8]	-7	hSpCas9	negative selection	11753773
3179530	3179553	19	-	28162770	HEL	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.09730469546583809	[53]	[36]	0	hSpCas9	negative selection	11753774
3179755	3179778	19	-	28162770	HEL	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	-0.15749165562386563	[201]	[115]	-1	hSpCas9	negative selection	11753775
3179330	3179353	19	-	28162770	HEL	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	0.29815553145268414	[352]	[277]	2	hSpCas9	negative selection	11753776
3179494	3179517	19	+	28162770	HEL	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	0.1371445699746917	[388]	[273]	1	hSpCas9	negative selection	11753777
3179181	3179204	19	-	28162770	MV411	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-4.507449951380693	[26]	[0]	-9	hSpCas9	negative selection	11923134
3179568	3179591	19	-	28162770	MV411	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	0.9915986463531855	[79]	[133]	8	hSpCas9	negative selection	11923135
3178785	3178808	19	+	28162770	MV411	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	-0.06667103964528776	[321]	[258]	0	hSpCas9	negative selection	11923136
3178822	3178845	19	+	28162770	MV411	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	-0.20463067944103552	[512]	[374]	-1	hSpCas9	negative selection	11923137
3178978	3179001	19	+	28162770	MV411	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	-0.4854583790743838	[235]	[141]	-4	hSpCas9	negative selection	11923138
3179365	3179388	19	-	28162770	MV411	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-0.5938647031981668	[42]	[23]	-4	hSpCas9	negative selection	11923139
3179530	3179553	19	-	28162770	MV411	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.6370852317972886	[47]	[25]	-4	hSpCas9	negative selection	11923140
3179755	3179778	19	-	28162770	MV411	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	-0.6370852317972889	[143]	[77]	-4	hSpCas9	negative selection	11923141
3179330	3179353	19	-	28162770	MV411	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	-0.10048575263753157	[307]	[241]	-1	hSpCas9	negative selection	11923142
3179494	3179517	19	+	28162770	MV411	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	0.08547007111938232	[338]	[302]	0	hSpCas9	negative selection	11923143
3179181	3179204	19	-	28162770	MONOMAC1	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-2.398670708229204	[22]	[4]	-9	hSpCas9	negative selection	12092500
3179568	3179591	19	-	28162770	MONOMAC1	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	1.8277950059203816	[71]	[292]	9	hSpCas9	negative selection	12092501
3178785	3178808	19	+	28162770	MONOMAC1	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.4082934513555644	[210]	[320]	4	hSpCas9	negative selection	12092502
3178822	3178845	19	+	28162770	MONOMAC1	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	-0.4656155173539822	[364]	[302]	-4	hSpCas9	negative selection	12092503
3178978	3179001	19	+	28162770	MONOMAC1	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	-1.0649333110522083	[145]	[79]	-7	hSpCas9	negative selection	12092504
3179365	3179388	19	-	28162770	MONOMAC1	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-3.241430966418007	[32]	[3]	-9	hSpCas9	negative selection	12092505
3179530	3179553	19	-	28162770	MONOMAC1	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.33454037080948873	[32]	[29]	-3	hSpCas9	negative selection	12092506
3179755	3179778	19	-	28162770	MONOMAC1	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	0.2944987896933335	[100]	[141]	3	hSpCas9	negative selection	12092507
3179330	3179353	19	-	28162770	MONOMAC1	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	-0.08421701672524862	[208]	[225]	0	hSpCas9	negative selection	12092508
3179494	3179517	19	+	28162770	MONOMAC1	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	0.661607303694905	[224]	[407]	6	hSpCas9	negative selection	12092509
3179181	3179204	19	-	28162770	OCIAML2	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-5.4706298252421615	[7]	[0]	-9	hSpCas9	negative selection	12261866
3179568	3179591	19	-	28162770	OCIAML2	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	0.19233518748026812	[11]	[75]	1	hSpCas9	negative selection	12261867
3178785	3178808	19	+	28162770	OCIAML2	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.30563132771387436	[66]	[458]	3	hSpCas9	negative selection	12261868
3178822	3178845	19	+	28162770	OCIAML2	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	-0.32767187140011833	[95]	[423]	-3	hSpCas9	negative selection	12261869
3178978	3179001	19	+	28162770	OCIAML2	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	-0.44893475414284223	[32]	[133]	-4	hSpCas9	negative selection	12261870
3179365	3179388	19	-	28162770	OCIAML2	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-0.47062982524216124	[10]	[43]	-4	hSpCas9	negative selection	12261871
3179530	3179553	19	-	28162770	OCIAML2	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	0.7517625960942866	[5]	[55]	7	hSpCas9	negative selection	12261872
3179755	3179778	19	-	28162770	OCIAML2	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	0.01933616154324815	[33]	[190]	0	hSpCas9	negative selection	12261873
3179330	3179353	19	-	28162770	OCIAML2	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	-0.12485498840043108	[59]	[304]	-1	hSpCas9	negative selection	12261874
3179494	3179517	19	+	28162770	OCIAML2	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	-0.3863932880741293	[78]	[334]	-3	hSpCas9	negative selection	12261875
3179181	3179204	19	-	28162770	OCIAML3	viability	GAGCAGGCTGAAGGTGGAGGCGG	S1PR4	ENSG00000125910	-2.786652718266559	[15]	[6]	-9	hSpCas9	negative selection	12431232
3179568	3179591	19	-	28162770	OCIAML3	viability	TGGGCCCCAGCACACCAGGAAGG	S1PR4	ENSG00000125910	0.7906562099111618	[26]	[140]	7	hSpCas9	negative selection	12431233
3178785	3178808	19	+	28162770	OCIAML3	viability	GGGAGGCCATGAACGCCACGGGG	S1PR4	ENSG00000125910	0.597523817307524	[80]	[369]	5	hSpCas9	negative selection	12431234
3178822	3178845	19	+	28162770	OCIAML3	viability	CGAGTCCTGCCAACAGCTGGCGG	S1PR4	ENSG00000125910	0.287470536111341	[167]	[618]	2	hSpCas9	negative selection	12431235
3178978	3179001	19	+	28162770	OCIAML3	viability	GGAGAACTTGCTGGTGCTGGCGG	S1PR4	ENSG00000125910	1.1274171029462647	[41]	[276]	8	hSpCas9	negative selection	12431236
3179365	3179388	19	-	28162770	OCIAML3	viability	GGGGCAGAAGGCTGGAGCAGCGG	S1PR4	ENSG00000125910	-2.352999540820368	[21]	[12]	-9	hSpCas9	negative selection	12431237
3179530	3179553	19	-	28162770	OCIAML3	viability	GCACCGTCTTCAGCAGGCGGCGG	S1PR4	ENSG00000125910	-0.9565777197088716	[17]	[27]	-6	hSpCas9	negative selection	12431238
3179755	3179778	19	-	28162770	OCIAML3	viability	GCCGGAGACACCCGCAGCAGAGG	S1PR4	ENSG00000125910	0.5024551991771281	[46]	[200]	4	hSpCas9	negative selection	12431239
3179330	3179353	19	-	28162770	OCIAML3	viability	AGGCAGTTCCAGCCCAGCAAAGG	S1PR4	ENSG00000125910	0.3385087629598498	[92]	[354]	3	hSpCas9	negative selection	12431240
3179494	3179517	19	+	28162770	OCIAML3	viability	GCAGAAGGCCCCACGCCCAGCGG	S1PR4	ENSG00000125910	0.3292111251883557	[81]	[310]	3	hSpCas9	negative selection	12431241