Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:53637
• Symbol:S1PR5
• Description:sphingosine-1-phosphate receptor 5

DataSource: http://genomecrispr.dkfz.de/#!/results/S1PR5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
10514607	10514630	19	+	26472758	Jiyoye	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-0.6752867786860997	[35]	[16]	-5	hSpCas9	negative selection	141794
10514421	10514444	19	+	26472758	Jiyoye	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	2.0930667910778107	[22]	[73]	9	hSpCas9	negative selection	141795
10514592	10514615	19	-	26472758	Jiyoye	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.60648418972928	[134]	[154]	4	hSpCas9	negative selection	141796
10514214	10514237	19	+	26472758	Jiyoye	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	-0.47083409411551613	[67]	[36]	-3	hSpCas9	negative selection	141797
10514106	10514129	19	+	26472758	Jiyoye	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	-0.2550522455419857	[325]	[205]	-2	hSpCas9	negative selection	141798
10514801	10514824	19	+	26472758	Jiyoye	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	2.157197128497526	[21]	[73]	9	hSpCas9	negative selection	141799
10514674	10514697	19	-	26472758	Jiyoye	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-0.3297902126603327	[79]	[47]	-2	hSpCas9	negative selection	141800
10514618	10514641	19	-	26472758	Jiyoye	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	0.577100382948186	[39]	[44]	4	hSpCas9	negative selection	141801
10514517	10514540	19	+	26472758	Jiyoye	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.36410665961398725	[101]	[98]	2	hSpCas9	negative selection	141802
10514485	10514508	19	+	26472758	Jiyoye	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	3.214530303563477	[0]	[6]	9	hSpCas9	negative selection	141803
10514607	10514630	19	+	26472758	KBM7	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	1.090629987281381	[151,133]	[237,57]	9	hSpCas9	negative selection	332912
10514421	10514444	19	+	26472758	KBM7	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.9131565093768708	[397,351]	[367,298]	8	hSpCas9	negative selection	332913
10514592	10514615	19	-	26472758	KBM7	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.7533256959537499	[709,737]	[723,446]	8	hSpCas9	negative selection	332914
10514214	10514237	19	+	26472758	KBM7	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	0.19634554972442309	[274,121]	[41,157]	2	hSpCas9	negative selection	332915
10514106	10514129	19	+	26472758	KBM7	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	0.6366562289348867	[829,545]	[536,456]	7	hSpCas9	negative selection	332916
10514801	10514824	19	+	26472758	KBM7	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	1.1229251152105397	[122,143]	[223,61]	9	hSpCas9	negative selection	332917
10514674	10514697	19	-	26472758	KBM7	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	0.5754141478681908	[299,378]	[272,213]	6	hSpCas9	negative selection	332918
10514618	10514641	19	-	26472758	KBM7	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	-0.4392523649207946	[314,368]	[145,96]	-4	hSpCas9	negative selection	332919
10514517	10514540	19	+	26472758	KBM7	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.5042439309775717	[559,519]	[397,326]	5	hSpCas9	negative selection	332920
10514485	10514508	19	+	26472758	KBM7	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	0.09328537892976074	[68,35]	[13,35]	0	hSpCas9	negative selection	332921
10514607	10514630	19	+	26472758	Raji	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-0.30070120326347727	[68]	[12]	-3	hSpCas9	negative selection	524030
10514421	10514444	19	+	26472758	Raji	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.12270433465735564	[280]	[70]	1	hSpCas9	negative selection	524031
10514592	10514615	19	-	26472758	Raji	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.8979301697446498	[184]	[79]	7	hSpCas9	negative selection	524032
10514214	10514237	19	+	26472758	Raji	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	0.14159925071151236	[124]	[31]	1	hSpCas9	negative selection	524033
10514106	10514129	19	+	26472758	Raji	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	0.17283659686221553	[236]	[61]	1	hSpCas9	negative selection	524034
10514801	10514824	19	+	26472758	Raji	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	0.21429873929011145	[51]	[13]	2	hSpCas9	negative selection	524035
10514674	10514697	19	-	26472758	Raji	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-0.025066760650049924	[170]	[38]	0	hSpCas9	negative selection	524036
10514618	10514641	19	-	26472758	Raji	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	0.6705196736415773	[110]	[40]	6	hSpCas9	negative selection	524037
10514517	10514540	19	+	26472758	Raji	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	1.7359353046424384	[162]	[125]	9	hSpCas9	negative selection	524038
10514485	10514508	19	+	26472758	Raji	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	2.844349129539806	[5]	[9]	9	hSpCas9	negative selection	524039
10514607	10514630	19	+	26472758	K562	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-0.05814404235398407	[110]	[89]	0	hSpCas9	negative selection	715148
10514421	10514444	19	+	26472758	K562	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	1.4611379405877005	[181]	[422]	9	hSpCas9	negative selection	715149
10514592	10514615	19	-	26472758	K562	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.34698846130699446	[474]	[509]	2	hSpCas9	negative selection	715150
10514214	10514237	19	+	26472758	K562	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	0.45477859350799776	[171]	[198]	3	hSpCas9	negative selection	715151
10514106	10514129	19	+	26472758	K562	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	-0.9622468205908836	[516]	[223]	-5	hSpCas9	negative selection	715152
10514801	10514824	19	+	26472758	K562	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	1.0863538814341955	[52]	[94]	8	hSpCas9	negative selection	715153
10514674	10514697	19	-	26472758	K562	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-0.6133286893757952	[385]	[212]	-4	hSpCas9	negative selection	715154
10514618	10514641	19	-	26472758	K562	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	0.28908777700017485	[158]	[163]	2	hSpCas9	negative selection	715155
10514517	10514540	19	+	26472758	K562	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	-0.15095849486137156	[412]	[313]	-1	hSpCas9	negative selection	715156
10514485	10514508	19	+	26472758	K562	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	-2.204888673697143	[70]	[12]	-7	hSpCas9	negative selection	715157
10513933	10513956	19	+	26627737	DLD1	viability	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	-0.5848763499048504	[254]	[47,42,65]	-5	hSpCas9	negative selection	802338
10514033	10514056	19	+	26627737	DLD1	viability	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.41590064271439553	[273]	[207,65,72]	4	hSpCas9	negative selection	802339
10514246	10514269	19	-	26627737	DLD1	viability	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.3324349167015255	[250]	[82,166,55]	3	hSpCas9	negative selection	802340
10514591	10514614	19	-	26627737	DLD1	viability	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	-0.2613369053073713	[918]	[251,229,236]	-3	hSpCas9	negative selection	802341
10514625	10514648	19	+	26627737	DLD1	viability	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	1.6169017567721737	[130]	[92,122,155]	9	hSpCas9	negative selection	802342
10513933	10513956	19	+	26627737	GBM cells	viability after 5 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.46140903548091144	[150]	[93,128]	7	hSpCas9	negative selection	884653
10514033	10514056	19	+	26627737	GBM cells	viability after 5 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.5094114677139793	[111]	[65,104]	7	hSpCas9	negative selection	884654
10514246	10514269	19	-	26627737	GBM cells	viability after 5 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.33354210252241023	[127]	[99,72]	5	hSpCas9	negative selection	884655
10514591	10514614	19	-	26627737	GBM cells	viability after 5 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	1.1463972771849638	[170]	[208,196]	9	hSpCas9	negative selection	884656
10514625	10514648	19	+	26627737	GBM cells	viability after 5 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	-0.019786023012466014	[68]	[32,39]	0	hSpCas9	negative selection	884657
10513933	10513956	19	+	26627737	GBM cells	viability after 13 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	-0.33785594842581335	[150]	[55,71]	-4	hSpCas9	negative selection	966968
10514033	10514056	19	+	26627737	GBM cells	viability after 13 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.469589142593687	[111]	[103,67]	6	hSpCas9	negative selection	966969
10514246	10514269	19	-	26627737	GBM cells	viability after 13 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.546811827490551	[127]	[117,87]	6	hSpCas9	negative selection	966970
10514591	10514614	19	-	26627737	GBM cells	viability after 13 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	1.1887143046674704	[170]	[232,193]	9	hSpCas9	negative selection	966971
10514625	10514648	19	+	26627737	GBM cells	viability after 13 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.05025048055799086	[68]	[51,27]	0	hSpCas9	negative selection	966972
10513933	10513956	19	+	26627737	GBM cells	viability after 21 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.734820553081517	[150]	[135,136]	7	hSpCas9	negative selection	1049283
10514033	10514056	19	+	26627737	GBM cells	viability after 21 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.16034121880839391	[111]	[67,67]	1	hSpCas9	negative selection	1049284
10514246	10514269	19	-	26627737	GBM cells	viability after 21 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.9607251590862629	[127]	[138,131]	8	hSpCas9	negative selection	1049285
10514591	10514614	19	-	26627737	GBM cells	viability after 21 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	1.3548392751637817	[170]	[234,239]	9	hSpCas9	negative selection	1049286
10514625	10514648	19	+	26627737	GBM cells	viability after 21 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.2578511151207763	[68]	[48,40]	2	hSpCas9	negative selection	1049287
10513933	10513956	19	+	26627737	RPE1	viability after 9 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.4666832050870642	[275]	[42,217]	3	hSpCas9	negative selection	1131598
10514033	10514056	19	+	26627737	RPE1	viability after 9 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.3537783648691952	[468]	[160,221]	2	hSpCas9	negative selection	1131599
10514246	10514269	19	-	26627737	RPE1	viability after 9 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.22541466540020194	[791]	[191,237]	-1	hSpCas9	negative selection	1131600
10514591	10514614	19	-	26627737	RPE1	viability after 9 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	1.1858019928524588	[467]	[362,294]	7	hSpCas9	negative selection	1131601
10514625	10514648	19	+	26627737	RPE1	viability after 9 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	3.188189774723914	[44]	[20,266]	9	hSpCas9	negative selection	1131602
10513933	10513956	19	+	26627737	RPE1	viability after 12 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.40019221068525357	[275]	[92,102]	2	hSpCas9	negative selection	1213913
10514033	10514056	19	+	26627737	RPE1	viability after 12 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.6189635626323952	[468]	[159,228]	4	hSpCas9	negative selection	1213914
10514246	10514269	19	-	26627737	RPE1	viability after 12 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.06102193871500253	[791]	[270,132]	0	hSpCas9	negative selection	1213915
10514591	10514614	19	-	26627737	RPE1	viability after 12 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	1.137404038352865	[467]	[279,272]	6	hSpCas9	negative selection	1213916
10514625	10514648	19	+	26627737	RPE1	viability after 12 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	3.325844261689233	[44]	[43,202]	9	hSpCas9	negative selection	1213917
10513933	10513956	19	+	26627737	RPE1	viability after 15 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.4154206125865325	[275]	[96,110]	2	hSpCas9	negative selection	1296228
10514033	10514056	19	+	26627737	RPE1	viability after 15 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.9321753543397748	[468]	[131,369]	5	hSpCas9	negative selection	1296229
10514246	10514269	19	-	26627737	RPE1	viability after 15 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.4412657501827956	[791]	[192,137]	-3	hSpCas9	negative selection	1296230
10514591	10514614	19	-	26627737	RPE1	viability after 15 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	1.5467302488331702	[467]	[511,265]	8	hSpCas9	negative selection	1296231
10514625	10514648	19	+	26627737	RPE1	viability after 15 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	3.206662712177965	[44]	[31,199]	9	hSpCas9	negative selection	1296232
10513933	10513956	19	+	26627737	RPE1	viability after 18 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.08223901637602316	[275]	[59,98]	0	hSpCas9	negative selection	1378543
10514033	10514056	19	+	26627737	RPE1	viability after 18 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	1.081522225897236	[468]	[248,287]	6	hSpCas9	negative selection	1378544
10514246	10514269	19	-	26627737	RPE1	viability after 18 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.28832097278787916	[791]	[262,80]	-2	hSpCas9	negative selection	1378545
10514591	10514614	19	-	26627737	RPE1	viability after 18 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	1.3877169025683678	[467]	[358,299]	7	hSpCas9	negative selection	1378546
10514625	10514648	19	+	26627737	RPE1	viability after 18 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	3.2336410784860847	[44]	[18,215]	9	hSpCas9	negative selection	1378547
10513933	10513956	19	+	26627737	HeLa	viability after 8 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.3689554950266125	[193]	[150,71,112]	3	hSpCas9	negative selection	1460858
10514033	10514056	19	+	26627737	HeLa	viability after 8 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	-0.7443064639307119	[380]	[97,133,66]	-6	hSpCas9	negative selection	1460859
10514246	10514269	19	-	26627737	HeLa	viability after 8 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.03187553360864093	[250]	[128,83,111]	0	hSpCas9	negative selection	1460860
10514591	10514614	19	-	26627737	HeLa	viability after 8 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	0.7147652202138155	[365]	[287,299,205]	6	hSpCas9	negative selection	1460861
10514625	10514648	19	+	26627737	HeLa	viability after 8 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.9470245606846472	[164]	[52,227,116]	7	hSpCas9	negative selection	1460862
10513933	10513956	19	+	26627737	HeLa	viability after 12 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.5407055485210293	[193]	[19,88,240]	4	hSpCas9	negative selection	1543173
10514033	10514056	19	+	26627737	HeLa	viability after 12 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	-0.2993582753052098	[380]	[64,146,167]	-3	hSpCas9	negative selection	1543174
10514246	10514269	19	-	26627737	HeLa	viability after 12 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.03942497641716036	[250]	[217,40,70]	0	hSpCas9	negative selection	1543175
10514591	10514614	19	-	26627737	HeLa	viability after 12 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	1.0860487088545407	[365]	[249,228,491]	7	hSpCas9	negative selection	1543176
10514625	10514648	19	+	26627737	HeLa	viability after 12 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.6189371456583376	[164]	[83,109,118]	5	hSpCas9	negative selection	1543177
10513933	10513956	19	+	26627737	HeLa	viability after 15 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.3079232923969184	[193]	[64,18,218]	2	hSpCas9	negative selection	1625488
10514033	10514056	19	+	26627737	HeLa	viability after 15 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.08810198085454071	[380]	[184,172,133]	0	hSpCas9	negative selection	1625489
10514246	10514269	19	-	26627737	HeLa	viability after 15 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.2346812489911862	[250]	[178,59,120]	2	hSpCas9	negative selection	1625490
10514591	10514614	19	-	26627737	HeLa	viability after 15 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	0.48513541248662984	[365]	[90,184,362]	4	hSpCas9	negative selection	1625491
10514625	10514648	19	+	26627737	HeLa	viability after 15 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.8460499356704807	[164]	[164,83,111]	6	hSpCas9	negative selection	1625492
10513933	10513956	19	+	26627737	HeLa	viability after 18 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.3048940792659227	[193]	[42,15,218]	2	hSpCas9	negative selection	1707803
10514033	10514056	19	+	26627737	HeLa	viability after 18 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.1422788373342014	[380]	[130,149,133]	1	hSpCas9	negative selection	1707804
10514246	10514269	19	-	26627737	HeLa	viability after 18 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.2936157133665817	[250]	[127,51,120]	2	hSpCas9	negative selection	1707805
10514591	10514614	19	-	26627737	HeLa	viability after 18 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	0.49362468391041714	[365]	[57,159,362]	4	hSpCas9	negative selection	1707806
10514625	10514648	19	+	26627737	HeLa	viability after 18 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.8463386690728589	[164]	[111,67,111]	6	hSpCas9	negative selection	1707807
10513933	10513956	19	+	26627737	HCT116	viability after 6 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	2.3647110181891433	[323]	[485,138]	9	hSpCas9	negative selection	1790118
10514033	10514056	19	+	26627737	HCT116	viability after 6 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.9561538592339126	[584]	[287,117]	5	hSpCas9	negative selection	1790119
10514246	10514269	19	-	26627737	HCT116	viability after 6 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.8198702506000874	[243]	[42,9]	-5	hSpCas9	negative selection	1790120
10514591	10514614	19	-	26627737	HCT116	viability after 6 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	1.8374618268207596	[523]	[441,212]	8	hSpCas9	negative selection	1790121
10514625	10514648	19	+	26627737	HCT116	viability after 6 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	3.128431188272896	[123]	[18,253]	9	hSpCas9	negative selection	1790122
10513933	10513956	19	+	26627737	HCT116	viability after 8 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	1.0765121628274028	[79]	[86,115,75]	8	hSpCas9	negative selection	1872433
10514033	10514056	19	+	26627737	HCT116	viability after 8 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.45260489274076693	[283]	[281,172,188]	5	hSpCas9	negative selection	1872434
10514246	10514269	19	-	26627737	HCT116	viability after 8 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.7292567127202412	[330]	[107,109,111]	-7	hSpCas9	negative selection	1872435
10514591	10514614	19	-	26627737	HCT116	viability after 8 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	-0.26814018080700536	[390]	[327,82,128]	-3	hSpCas9	negative selection	1872436
10514625	10514648	19	+	26627737	HCT116	viability after 8 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	-1.2575800898892782	[417]	[106,69,111]	-9	hSpCas9	negative selection	1872437
10513933	10513956	19	+	26627737	HCT116	viability after 9 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.5218495254860072	[323]	[207,57]	4	hSpCas9	negative selection	1954748
10514033	10514056	19	+	26627737	HCT116	viability after 9 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	-0.9013434663392502	[584]	[110,61]	-6	hSpCas9	negative selection	1954749
10514246	10514269	19	-	26627737	HCT116	viability after 9 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.08258855229063711	[243]	[49,83]	0	hSpCas9	negative selection	1954750
10514591	10514614	19	-	26627737	HCT116	viability after 9 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	0.9537158511698899	[523]	[270,270]	6	hSpCas9	negative selection	1954751
10514625	10514648	19	+	26627737	HCT116	viability after 9 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	1.3697856754748248	[123]	[41,119]	8	hSpCas9	negative selection	1954752
10513933	10513956	19	+	26627737	HCT116	viability after 12 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.8159181080530116	[79]	[87,81,50]	7	hSpCas9	negative selection	2037063
10514033	10514056	19	+	26627737	HCT116	viability after 12 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.18339338218805928	[283]	[111,272,130]	2	hSpCas9	negative selection	2037064
10514246	10514269	19	-	26627737	HCT116	viability after 12 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.4085378273698585	[330]	[89,140,165]	-4	hSpCas9	negative selection	2037065
10514591	10514614	19	-	26627737	HCT116	viability after 12 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	-0.24993560442174434	[390]	[133,139,246]	-3	hSpCas9	negative selection	2037066
10514625	10514648	19	+	26627737	HCT116	viability after 12 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	-1.7604422024532633	[417]	[27,33,134]	-9	hSpCas9	negative selection	2037067
10513933	10513956	19	+	26627737	HCT116	viability after 15 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.8367552216193903	[79]	[100,108,38]	7	hSpCas9	negative selection	2119378
10514033	10514056	19	+	26627737	HCT116	viability after 15 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.1390794764413596	[283]	[158,171,204]	1	hSpCas9	negative selection	2119379
10514246	10514269	19	-	26627737	HCT116	viability after 15 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.7870487619299877	[330]	[144,101,87]	-7	hSpCas9	negative selection	2119380
10514591	10514614	19	-	26627737	HCT116	viability after 15 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	-0.8123759599838992	[390]	[114,135,130]	-7	hSpCas9	negative selection	2119381
10514625	10514648	19	+	26627737	HCT116	viability after 15 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	-2.1827829880607363	[417]	[39,59,56]	-9	hSpCas9	negative selection	2119382
10513933	10513956	19	+	26627737	HCT116	viability after 18 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.8052760036270639	[79]	[96,61,42]	6	hSpCas9	negative selection	2201693
10514033	10514056	19	+	26627737	HCT116	viability after 18 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.7726136390026144	[283]	[320,84,310]	6	hSpCas9	negative selection	2201694
10514246	10514269	19	-	26627737	HCT116	viability after 18 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.4166408718671568	[330]	[136,126,93]	-4	hSpCas9	negative selection	2201695
10514591	10514614	19	-	26627737	HCT116	viability after 18 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	-0.7151624166701562	[390]	[135,135,69]	-6	hSpCas9	negative selection	2201696
10514625	10514648	19	+	26627737	HCT116	viability after 18 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	-1.7540817937971547	[417]	[66,28,86]	-8	hSpCas9	negative selection	2201697
10517516	10517539	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGCAACTGCTGGCGACCGCCGG	S1PR5	ENSG00000180739	3.427744175983304	[0,5]	[1,16]	9	dCas9-VP64	positive selection	2457467
10517537	10517560	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCCGGGACCCAAGGGGAGGGG	S1PR5	ENSG00000180739	1.4555330468034744	[3,1]	[0,1]	5	dCas9-VP64	positive selection	2457468
10517565	10517588	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGCACAGGCTGGCAGCCATGGG	S1PR5	ENSG00000180739	2.1815077648362022	[0,0]	[0,0]	7	dCas9-VP64	positive selection	2457469
10517516	10517539	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGCAACTGCTGGCGACCGCCGG	S1PR5	ENSG00000180739	-0.9632999813609957	[27,75]	[8,7]	-8	dCas9-VP64	positive selection	2552722
10517537	10517560	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCCGGGACCCAAGGGGAGGGG	S1PR5	ENSG00000180739	3.6729261577282983	[18,6]	[110,1]	9	dCas9-VP64	positive selection	2552723
10517565	10517588	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGCACAGGCTGGCAGCCATGGG	S1PR5	ENSG00000180739	1.5639086887007707	[0,0]	[0,0]	8	dCas9-VP64	positive selection	2552724
10514932	10514955	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACTACACCGGCAAGCTCCGCGG	S1PR5	ENSG00000180739	0.29035912503519534	[2,2]	[3,2]	6	hSpCas9	positive selection	3018519
10514626	10514649	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.18652311618748105	[2,2]	[2,2]	4	hSpCas9	positive selection	3018520
10514872	10514895	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACACCGCCAGGCACACCACGG	S1PR5	ENSG00000180739	-0.08414134479803037	[2,2]	[2,1]	-1	hSpCas9	positive selection	3018521
10514600	10514623	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGAGCGCAGCCTCACCATGG	S1PR5	ENSG00000180739	0.5769595474529869	[2,3]	[3,4]	9	hSpCas9	positive selection	3018522
10514932	10514955	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACTACACCGGCAAGCTCCGCGG	S1PR5	ENSG00000180739	0.14329284393304795	[2,2]	[1,2]	2	hSpCas9	positive selection	3086377
10514626	10514649	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	-0.7339521849517203	[2,2]	[1,0]	-8	hSpCas9	positive selection	3086378
10514872	10514895	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACACCGCCAGGCACACCACGG	S1PR5	ENSG00000180739	0.9930294919380545	[2,2]	[5,3]	9	hSpCas9	positive selection	3086379
10514600	10514623	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGAGCGCAGCCTCACCATGG	S1PR5	ENSG00000180739	-0.29487164035273805	[2,2]	[2,0]	-4	hSpCas9	positive selection	3086380
10514276	10514299		+	24336571	A375	resistance to PLX after 7 days	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	-0.14809732366259087	[7,6]	[4,7]	-5	hSpCas9	positive selection	3142434
10514373	10514396		+	24336571	A375	resistance to PLX after 7 days	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.044665524000808254	[7,6]	[6,8]	1	hSpCas9	positive selection	3142435
10514276	10514299		+	24336571	A375	resistance to PLX after 14 days	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.016010010625941318	[4,4]	[1,1]	0	hSpCas9	positive selection	3200227
10514373	10514396		+	24336571	A375	resistance to PLX after 14 days	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.26875925545551127	[9,1]	[3,2]	2	hSpCas9	positive selection	3200228
10514276	10514299		+	24336571	A375	viability after 7 days	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.33985641748198936	[5]	[7,6]	5	hSpCas9	negative selection	3258020
10514373	10514396		+	24336571	A375	viability after 7 days	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.10067644602766879	[7]	[7,6]	1	hSpCas9	negative selection	3258021
10514276	10514299		+	24336571	A375	viability after 14 days	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	-0.13581561634941686	[5]	[4,4]	-1	hSpCas9	negative selection	3315813
10514373	10514396		+	24336571	A375	viability after 14 days	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.20186791084810418	[7]	[9,1]	-2	hSpCas9	negative selection	3315814
10513897	10513920	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	3.7978945928085377	[10,10]	[0,0]	9	hSpCas9	positive selection	3391081
10514915	10514938	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	1.2800462879459185	[62,62]	[0,0]	5	hSpCas9	positive selection	3391082
10513985	10514008	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	1.3031299010589596	[61,61]	[0,0]	5	hSpCas9	positive selection	3391083
10514932	10514955	19	-	26780180	HT29	viability (Avana library 4 designs)	AACTACACCGGCAAGCTCCGCGG	S1PR5	ENSG00000180739	0.999195151547062	[]	[]	4	hSpCas9	negative selection	3456924
10514625	10514648	19	+	26780180	HT29	viability (Avana library 4 designs)	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	2.3604448667708	[]	[]	8	hSpCas9	negative selection	3456925
10514871	10514894	19	+	26780180	HT29	viability (Avana library 4 designs)	GCACACCGCCAGGCACACCACGG	S1PR5	ENSG00000180739	1.75928543430658	[]	[]	6	hSpCas9	negative selection	3456926
10514600	10514623	19	-	26780180	HT29	viability (Avana library 4 designs)	GCTGGAGCGCAGCCTCACCATGG	S1PR5	ENSG00000180739	1.2583879369944	[]	[]	5	hSpCas9	negative selection	3456927
10514871	10514894	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACACCGCCAGGCACACCACGG	S1PR5	ENSG00000180739	-0.613490319013674	[]	[]	-1	hSpCas9	negative selection	3555634
10514932	10514955	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AACTACACCGGCAAGCTCCGCGG	S1PR5	ENSG00000180739	-0.18556415242962	[]	[]	0	hSpCas9	negative selection	3555635
10514625	10514648	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	5.61921182070688	[]	[]	8	hSpCas9	negative selection	3555636
10514600	10514623	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGAGCGCAGCCTCACCATGG	S1PR5	ENSG00000180739	3.75538391299003	[]	[]	6	hSpCas9	negative selection	3555637
10514415	10514438	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCACGCAGAAGAGCACGTAGG	S1PR5	ENSG00000180739	-10.2450886243228	[]	[]	-7	hSpCas9	negative selection	3555638
10514482	10514505	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCTGGGCTGGAATTGCCTGGG	S1PR5	ENSG00000180739	2.26520654563684	[]	[]	3	hSpCas9	negative selection	3555639
10514871	10514894	19	+	26780180	A375	viability (Avana lentiGuide)	GCACACCGCCAGGCACACCACGG	S1PR5	ENSG00000180739	0.410046943078744	[]	[]	0	hSpCas9	negative selection	3664293
10514932	10514955	19	-	26780180	A375	viability (Avana lentiGuide)	AACTACACCGGCAAGCTCCGCGG	S1PR5	ENSG00000180739	3.11511087787916	[]	[]	3	hSpCas9	negative selection	3664294
10514625	10514648	19	+	26780180	A375	viability (Avana lentiGuide)	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.748653202930366	[]	[]	0	hSpCas9	negative selection	3664295
10514600	10514623	19	-	26780180	A375	viability (Avana lentiGuide)	GCTGGAGCGCAGCCTCACCATGG	S1PR5	ENSG00000180739	3.65013492235825	[]	[]	3	hSpCas9	negative selection	3664296
10514415	10514438	19	+	26780180	A375	viability (Avana lentiGuide)	GAGCACGCAGAAGAGCACGTAGG	S1PR5	ENSG00000180739	3.29279987519562	[]	[]	3	hSpCas9	negative selection	3664297
10514482	10514505	19	-	26780180	A375	viability (Avana lentiGuide)	GCGCTGGGCTGGAATTGCCTGGG	S1PR5	ENSG00000180739	8.37999091786676	[]	[]	6	hSpCas9	negative selection	3664298
10514871	10514894	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACACCGCCAGGCACACCACGG	S1PR5	ENSG00000180739	-0.5627661766145138	[3]	[1,2]	-7	hSpCas9	positive selection	3772900
10514932	10514955	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACTACACCGGCAAGCTCCGCGG	S1PR5	ENSG00000180739	-0.18089305568820033	[4]	[4,3]	-3	hSpCas9	positive selection	3772901
10514625	10514648	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.19467030161291107	[4]	[5,4]	5	hSpCas9	positive selection	3772902
10514600	10514623	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGAGCGCAGCCTCACCATGG	S1PR5	ENSG00000180739	0.3483782741173098	[4]	[5,5]	9	hSpCas9	positive selection	3772903
10514415	10514438	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCACGCAGAAGAGCACGTAGG	S1PR5	ENSG00000180739	-0.5502241430204259	[4]	[3,1]	-7	hSpCas9	positive selection	3772904
10514482	10514505	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCTGGGCTGGAATTGCCTGGG	S1PR5	ENSG00000180739	0.09007901466578216	[4]	[4,4]	2	hSpCas9	positive selection	3772905
10514871	10514894	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACACCGCCAGGCACACCACGG	S1PR5	ENSG00000180739	0.21225950727585444	[4]	[5,3]	5	hSpCas9	positive selection	3881507
10514932	10514955	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACTACACCGGCAAGCTCCGCGG	S1PR5	ENSG00000180739	-0.5948091499238848	[4]	[2,1]	-6	hSpCas9	positive selection	3881508
10514625	10514648	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	-0.2800736788171296	[4]	[0,4]	-4	hSpCas9	positive selection	3881509
10514600	10514623	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGAGCGCAGCCTCACCATGG	S1PR5	ENSG00000180739	-0.03945916022320367	[4]	[3,3]	0	hSpCas9	positive selection	3881510
10514415	10514438	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCACGCAGAAGAGCACGTAGG	S1PR5	ENSG00000180739	-0.16903745235957404	[5]	[4,3]	-2	hSpCas9	positive selection	3881511
10514482	10514505	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCTGGGCTGGAATTGCCTGGG	S1PR5	ENSG00000180739	0.16420646302514805	[4]	[3,5]	4	hSpCas9	positive selection	3881512
10514276	10514299	19	+	26780180	A375	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.676825505423154	[]	[]	2	hSpCas9	negative selection	3991525
10513985	10514008	19	+	26780180	A375	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.780628653057342	[]	[]	3	hSpCas9	negative selection	3991526
10514915	10514938	19	-	26780180	A375	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	1.00413025816608	[]	[]	4	hSpCas9	negative selection	3991527
10514373	10514396	19	+	26780180	A375	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.707969762351781	[]	[]	2	hSpCas9	negative selection	3991528
10513897	10513920	19	-	26780180	A375	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.357670081272324	[]	[]	0	hSpCas9	negative selection	3991529
10514270	10514293	19	-	26780180	A375	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.500890048683723	[]	[]	1	hSpCas9	negative selection	3991530
10514276	10514299	19	+	26780180	HT29	viability (GeCKOv2 library)	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.115864102015551	[]	[]	0	hSpCas9	negative selection	4099491
10513985	10514008	19	+	26780180	HT29	viability (GeCKOv2 library)	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	1.69583021581475	[]	[]	8	hSpCas9	negative selection	4099492
10514915	10514938	19	-	26780180	HT29	viability (GeCKOv2 library)	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	1.0655402233944	[]	[]	5	hSpCas9	negative selection	4099493
10514373	10514396	19	+	26780180	HT29	viability (GeCKOv2 library)	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	1.110641093588	[]	[]	5	hSpCas9	negative selection	4099494
10513897	10513920	19	-	26780180	HT29	viability (GeCKOv2 library)	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.744356972604068	[]	[]	3	hSpCas9	negative selection	4099495
10514270	10514293	19	-	26780180	HT29	viability (GeCKOv2 library)	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.606925298373119	[]	[]	2	hSpCas9	negative selection	4099496
10514276	10514299	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	-0.22285302888583108	[2]	[1,0]	-5	hSpCas9	positive selection	4168172
10514373	10514396	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.06592998195183791	[2]	[1,1]	-1	hSpCas9	positive selection	4168173
10514276	10514299	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	-0.02385945976414139	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4232194
10514373	10514396	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.2052791212929625	[3]	[1,2,1,0]	-3	hSpCas9	positive selection	4232195
10514276	10514299	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.08919834880246891	[1]	[2,0]	1	hSpCas9	positive selection	4296235
10514373	10514396	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.04796545133801065	[2]	[2,1]	1	hSpCas9	positive selection	4296236
10514270	10514293	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.4166855409859947	[1]	[2,1]	8	hSpCas9	positive selection	4296237
10513897	10513920	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.1252871759168641	[0]	[0,0]	2	hSpCas9	positive selection	4360489
10514915	10514938	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-0.0810232087198185	[1]	[1,0]	-1	hSpCas9	positive selection	4360490
10513985	10514008	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	-0.017603834627347548	[1]	[1,0]	0	hSpCas9	positive selection	4360491
10514432	10514454	19	+	27760321	OCIAML3	viability	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	0.5548626512736664	[538,424]	[521,586]	6	hSpCas9	negative selection	4436637
10514680	10514702	19	+	27760321	OCIAML3	viability	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	0.37793662413807977	[556,543]	[443,712]	4	hSpCas9	negative selection	4436638
10514699	10514721	19	+	27760321	OCIAML3	viability	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.38146882838886853	[983,870]	[783,1150]	4	hSpCas9	negative selection	4436639
10514728	10514750	19	+	27760321	OCIAML3	viability	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	0.24917086566294444	[787,638]	[614,717]	3	hSpCas9	negative selection	4436640
10514848	10514870	19	+	27760321	OCIAML3	viability	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	0.668910804183066	[396,363]	[383,588]	7	hSpCas9	negative selection	4436641
10514432	10514454	19	+	27760321	OCIAML2	viability	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	0.6107444213517463	[538,424]	[607,569]	8	hSpCas9	negative selection	4520100
10514680	10514702	19	+	27760321	OCIAML2	viability	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	-0.8669086130730921	[556,543]	[176,333]	-7	hSpCas9	negative selection	4520101
10514699	10514721	19	+	27760321	OCIAML2	viability	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.3546426942582599	[983,870]	[826,1129]	5	hSpCas9	negative selection	4520102
10514728	10514750	19	+	27760321	OCIAML2	viability	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	0.062164088484845226	[787,638]	[516,707]	0	hSpCas9	negative selection	4520103
10514848	10514870	19	+	27760321	OCIAML2	viability	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	0.6119079000173403	[396,363]	[427,525]	8	hSpCas9	negative selection	4520104
10514432	10514454	19	+	27760321	MV411	viability	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	0.18986519101463448	[538,424]	[457,213]	1	hSpCas9	negative selection	4603563
10514680	10514702	19	+	27760321	MV411	viability	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	-1.743499758471132	[556,543]	[37,214]	-8	hSpCas9	negative selection	4603564
10514699	10514721	19	+	27760321	MV411	viability	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.6533311880295638	[983,870]	[466,1702]	5	hSpCas9	negative selection	4603565
10514728	10514750	19	+	27760321	MV411	viability	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	-0.6847191262774152	[787,638]	[258,339]	-5	hSpCas9	negative selection	4603566
10514848	10514870	19	+	27760321	MV411	viability	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	0.6895285468861049	[396,363]	[210,695]	5	hSpCas9	negative selection	4603567
10514432	10514454	19	+	27760321	HL60	viability	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	0.5423137036180345	[538,424]	[493,649]	6	hSpCas9	negative selection	4687026
10514680	10514702	19	+	27760321	HL60	viability	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	-0.8298912209275796	[556,543]	[172,338]	-7	hSpCas9	negative selection	4687027
10514699	10514721	19	+	27760321	HL60	viability	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.4133688376002693	[983,870]	[917,1101]	5	hSpCas9	negative selection	4687028
10514728	10514750	19	+	27760321	HL60	viability	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	0.7995167652998153	[787,638]	[1044,970]	8	hSpCas9	negative selection	4687029
10514848	10514870	19	+	27760321	HL60	viability	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	0.15200785305673206	[396,363]	[353,335]	1	hSpCas9	negative selection	4687030
10514432	10514454	19	+	27760321	HT1080	viability	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	1.3072241744328676	[424,331]	[523,207]	7	hSpCas9	negative selection	4770489
10514680	10514702	19	+	27760321	HT1080	viability	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	0.7190395166129668	[543,424]	[564,46]	4	hSpCas9	negative selection	4770490
10514699	10514721	19	+	27760321	HT1080	viability	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.9698877900580387	[870,679]	[417,809]	5	hSpCas9	negative selection	4770491
10514728	10514750	19	+	27760321	HT1080	viability	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	-1.696025716187544	[638,498]	[26,116]	-6	hSpCas9	negative selection	4770492
10514848	10514870	19	+	27760321	HT1080	viability	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	0.7682346154971038	[363,283]	[152,292]	4	hSpCas9	negative selection	4770493
10514432	10514454	19	+	27760321	HT29	viability after 7 days	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	0.4265812003825436	[424,331]	[729,740,505]	6	hSpCas9	negative selection	4853952
10514680	10514702	19	+	27760321	HT29	viability after 7 days	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	-0.8574539022079248	[543,424]	[496,407,153]	-8	hSpCas9	negative selection	4853953
10514699	10514721	19	+	27760321	HT29	viability after 7 days	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.3907930767035681	[870,679]	[1782,1220,993]	6	hSpCas9	negative selection	4853954
10514728	10514750	19	+	27760321	HT29	viability after 7 days	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	-0.38670929559506967	[638,498]	[851,510,362]	-5	hSpCas9	negative selection	4853955
10514848	10514870	19	+	27760321	HT29	viability after 7 days	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	-0.090791262871247	[363,283]	[403,260,505]	-1	hSpCas9	negative selection	4853956
10514432	10514454	19	+	27760321	HT29	viability after 25 days	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	0.3679473242390144	[424,331]	[565,595,505]	4	hSpCas9	negative selection	4937415
10514680	10514702	19	+	27760321	HT29	viability after 25 days	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	-0.35187472598856856	[543,424]	[474,461,352]	-4	hSpCas9	negative selection	4937416
10514699	10514721	19	+	27760321	HT29	viability after 25 days	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.34556493313833525	[870,679]	[1183,1192,980]	3	hSpCas9	negative selection	4937417
10514728	10514750	19	+	27760321	HT29	viability after 25 days	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	-0.1286369166259137	[638,498]	[510,603,682]	-1	hSpCas9	negative selection	4937418
10514848	10514870	19	+	27760321	HT29	viability after 25 days	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	-0.1194252469788368	[363,283]	[343,326,351]	-1	hSpCas9	negative selection	4937419
10514432	10514454	19	+	27760321	HT29	viability after 22 days	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	0.45251151472281764	[424,331]	[485,551,762]	5	hSpCas9	negative selection	5020878
10514680	10514702	19	+	27760321	HT29	viability after 22 days	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	-0.07867330019146856	[543,424]	[386,791,414]	-1	hSpCas9	negative selection	5020879
10514699	10514721	19	+	27760321	HT29	viability after 22 days	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.5128248030769416	[870,679]	[1571,1152,1102]	5	hSpCas9	negative selection	5020880
10514728	10514750	19	+	27760321	HT29	viability after 22 days	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	-0.1524536816789549	[638,498]	[353,621,807]	-1	hSpCas9	negative selection	5020881
10514848	10514870	19	+	27760321	HT29	viability after 22 days	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	0.044983178668758436	[363,283]	[361,399,397]	0	hSpCas9	negative selection	5020882
10514432	10514454	19	+	27760321	HT29	viability after 19 days	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	0.239184947094506	[424,331]	[588,447,503]	2	hSpCas9	negative selection	5104341
10514680	10514702	19	+	27760321	HT29	viability after 19 days	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	-0.34741371647651714	[543,424]	[308,732,257]	-3	hSpCas9	negative selection	5104342
10514699	10514721	19	+	27760321	HT29	viability after 19 days	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.34046921651551365	[870,679]	[1610,916,899]	3	hSpCas9	negative selection	5104343
10514728	10514750	19	+	27760321	HT29	viability after 19 days	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	-0.3424326757187632	[638,498]	[627,584,344]	-3	hSpCas9	negative selection	5104344
10514848	10514870	19	+	27760321	HT29	viability after 19 days	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	0.1967448971214935	[363,283]	[706,189,406]	1	hSpCas9	negative selection	5104345
10514432	10514454	19	+	27760321	HT29	viability after 16 days	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	-0.04593380841743541	[424,331]	[336,282,606]	0	hSpCas9	negative selection	5187804
10514680	10514702	19	+	27760321	HT29	viability after 16 days	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	-0.5124397470809662	[543,424]	[330,394,408]	-5	hSpCas9	negative selection	5187805
10514699	10514721	19	+	27760321	HT29	viability after 16 days	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.27802661130137896	[870,679]	[1487,790,924]	3	hSpCas9	negative selection	5187806
10514728	10514750	19	+	27760321	HT29	viability after 16 days	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	-0.7213522339042747	[638,498]	[435,310,417]	-6	hSpCas9	negative selection	5187807
10514848	10514870	19	+	27760321	HT29	viability after 16 days	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	-0.5049104210141129	[363,283]	[286,265,215]	-5	hSpCas9	negative selection	5187808
10514432	10514454	19	+	27760321	HT29	viability after 13 days	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	0.13760430366993864	[424,331]	[686,420,348]	1	hSpCas9	negative selection	5271267
10514680	10514702	19	+	27760321	HT29	viability after 13 days	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	-0.7011919952790313	[543,424]	[304,518,220]	-6	hSpCas9	negative selection	5271268
10514699	10514721	19	+	27760321	HT29	viability after 13 days	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.2906627372826798	[870,679]	[1306,1271,743]	3	hSpCas9	negative selection	5271269
10514728	10514750	19	+	27760321	HT29	viability after 13 days	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	-0.22082354713974617	[638,498]	[543,788,377]	-3	hSpCas9	negative selection	5271270
10514848	10514870	19	+	27760321	HT29	viability after 13 days	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	0.007219877687953846	[363,283]	[443,412,281]	0	hSpCas9	negative selection	5271271
10514432	10514454	19	+	27760321	HT29	viability after 10 days	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	0.29033459531625433	[424,331]	[799,502,431]	4	hSpCas9	negative selection	5354730
10514680	10514702	19	+	27760321	HT29	viability after 10 days	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	0.027799728207304197	[543,424]	[566,616,664]	0	hSpCas9	negative selection	5354731
10514699	10514721	19	+	27760321	HT29	viability after 10 days	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	-0.03640408028219899	[870,679]	[889,1102,845]	0	hSpCas9	negative selection	5354732
10514728	10514750	19	+	27760321	HT29	viability after 10 days	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	-0.31623154182877594	[638,498]	[672,509,527]	-4	hSpCas9	negative selection	5354733
10514848	10514870	19	+	27760321	HT29	viability after 10 days	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	-0.6082424563225328	[363,283]	[379,212,202]	-6	hSpCas9	negative selection	5354734
10514432	10514454	19	+	27760321	MOLM13	viability	CGTAGGCCTTGGCGTAGAGCGG	S1PR5	ENSG00000180739	0.43276010529433373	[538,424]	[455,286]	3	hSpCas9	negative selection	5438193
10514680	10514702	19	+	27760321	MOLM13	viability	CGTGCGAACCAGAGCGCGGGGG	S1PR5	ENSG00000180739	2.293000360557788	[556,543]	[2935,324]	9	hSpCas9	negative selection	5438194
10514699	10514721	19	+	27760321	MOLM13	viability	GGGACAGTTTCAGCGTGAGCGG	S1PR5	ENSG00000180739	0.4962166310714833	[983,870]	[1007,505]	3	hSpCas9	negative selection	5438195
10514728	10514750	19	+	27760321	MOLM13	viability	AGTAGGATGTTGGCGGCGTAGG	S1PR5	ENSG00000180739	0.49001902831232436	[787,638]	[489,623]	3	hSpCas9	negative selection	5438196
10514848	10514870	19	+	27760321	MOLM13	viability	AGATTCTCTAGCACGATGAAGG	S1PR5	ENSG00000180739	-0.2286380610137672	[396,363]	[106,247]	-1	hSpCas9	negative selection	5438197
10517034	10517057	19	+	27661255	K562	viability	GGCTCACCCATGCTGGAGGTGGG	S1PR5	ENSG00000180739	0.12330871613060368	[239,257]	[278,162]	4	dCas9-KRAB	negative selection	5509169
10517356	10517379	19	+	27661255	K562	viability	GCCCAGCCCAGCGCCCCCAAAGG	S1PR5	ENSG00000180739	-0.07088925786943379	[245,349]	[235,215]	-3	dCas9-KRAB	negative selection	5509170
10517205	10517228	19	-	27661255	K562	viability	GGTGCAGGACCTGGGATACGGGG	S1PR5	ENSG00000180739	0.09072323178956099	[1412,1381]	[1408,1001]	3	dCas9-KRAB	negative selection	5509171
10517380	10517403	19	-	27661255	K562	viability	GCAGAGTGAGTGGACTGCACTGG	S1PR5	ENSG00000180739	0.13038921812201898	[1101,1238]	[1064,983]	4	dCas9-KRAB	negative selection	5509172
10514276	10514299	19	+	27260156	BXPC3	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.7981717218341906	[102]	[210,115,196,230]	9	hSpCas9	negative selection	5568695
10514373	10514396	19	+	27260156	BXPC3	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.12311885829386388	[360]	[367,426,378,478]	2	hSpCas9	negative selection	5568696
10514270	10514293	19	-	27260156	BXPC3	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.6701300702878661	[192]	[333,212,370,376]	9	hSpCas9	negative selection	5568697
10513897	10513920	19	-	27260156	BXPC3	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.013599373858899977	[38]	[14,23,89,39]	0	hSpCas9	negative selection	5632949
10514915	10514938	19	-	27260156	BXPC3	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-0.18502624267995382	[131]	[95,137,95,160]	-4	hSpCas9	negative selection	5632950
10513985	10514008	19	+	27260156	BXPC3	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	-0.003377704451880126	[185]	[188,210,154,221]	0	hSpCas9	negative selection	5632951
10514276	10514299	19	+	27260156	A673	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.6376621509874183	[102]	[230,170,214,154]	9	hSpCas9	negative selection	5689946
10514373	10514396	19	+	27260156	A673	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.3213677846564244	[360]	[310,249,346,484]	-7	hSpCas9	negative selection	5689947
10514270	10514293	19	-	27260156	A673	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.5604311592584066	[192]	[368,342,310,346]	9	hSpCas9	negative selection	5689948
10513897	10513920	19	-	27260156	A673	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.04242382636454378	[38]	[45,40,66,37]	1	hSpCas9	negative selection	5754200
10514915	10514938	19	-	27260156	A673	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-0.13542871654683042	[131]	[207,83,116,178]	-3	hSpCas9	negative selection	5754201
10513985	10514008	19	+	27260156	A673	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.12254189791698744	[185]	[215,266,231,253]	3	hSpCas9	negative selection	5754202
10514276	10514299	19	+	27260156	A375	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.9690436593572096	[102]	[237,450,119,169]	9	hSpCas9	negative selection	5811197
10514373	10514396	19	+	27260156	A375	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.22210874868505776	[360]	[485,608,499,397]	3	hSpCas9	negative selection	5811198
10514270	10514293	19	-	27260156	A375	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.9189620059564092	[192]	[423,432,391,451]	9	hSpCas9	negative selection	5811199
10513897	10513920	19	-	27260156	A375	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.6016667391447372	[38]	[68,69,101,38]	8	hSpCas9	negative selection	5875451
10514915	10514938	19	-	27260156	A375	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.18424964404520794	[131]	[149,334,125,117]	2	hSpCas9	negative selection	5875452
10513985	10514008	19	+	27260156	A375	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.8048595529216498	[185]	[393,509,381,262]	9	hSpCas9	negative selection	5875453
10514276	10514299	19	+	27260156	COLO741	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.2941610150544778	[102]	[138,182,159]	6	hSpCas9	negative selection	5932448
10514373	10514396	19	+	27260156	COLO741	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.39988511749977623	[360]	[452,329,278]	-7	hSpCas9	negative selection	5932449
10514270	10514293	19	-	27260156	COLO741	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.16111356110506714	[192]	[214,336,269]	3	hSpCas9	negative selection	5932450
10513897	10513920	19	-	27260156	COLO741	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.21213312597144363	[38]	[50,56,63]	4	hSpCas9	negative selection	5996702
10514915	10514938	19	-	27260156	COLO741	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.39309113442874555	[131]	[215,246,201]	7	hSpCas9	negative selection	5996703
10513985	10514008	19	+	27260156	COLO741	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.18816233421217476	[185]	[285,270,256]	4	hSpCas9	negative selection	5996704
10514276	10514299	19	+	27260156	CAL120	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	1.2064181073695903	[102]	[564,250,114]	9	hSpCas9	negative selection	6053699
10514373	10514396	19	+	27260156	CAL120	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.7208989128645553	[360]	[286,219,311]	-7	hSpCas9	negative selection	6053700
10514270	10514293	19	-	27260156	CAL120	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.2798170166541536	[192]	[451,225,221]	4	hSpCas9	negative selection	6053701
10513897	10513920	19	-	27260156	CAL120	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.45891949534034904	[38]	[33,28,130]	7	hSpCas9	negative selection	6117953
10514915	10514938	19	-	27260156	CAL120	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-0.08688269203595	[131]	[141,108,209]	-1	hSpCas9	negative selection	6117954
10513985	10514008	19	+	27260156	CAL120	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.1717160341910906	[185]	[153,296,313]	2	hSpCas9	negative selection	6117955
10514276	10514299	19	+	27260156	CADOES1	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.7783552763719903	[102]	[167,221,111,154]	9	hSpCas9	negative selection	6174950
10514373	10514396	19	+	27260156	CADOES1	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.02627703593670916	[360]	[382,484,206,290]	0	hSpCas9	negative selection	6174951
10514270	10514293	19	-	27260156	CADOES1	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.5852289721006514	[192]	[297,311,203,262]	8	hSpCas9	negative selection	6174952
10513897	10513920	19	-	27260156	CADOES1	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-0.009667661718573584	[38]	[64,54,15,6]	0	hSpCas9	negative selection	6239204
10514915	10514938	19	-	27260156	CADOES1	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-0.31730117816489245	[131]	[44,83,171,92]	-5	hSpCas9	negative selection	6239205
10513985	10514008	19	+	27260156	CADOES1	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.27513827223628584	[185]	[203,244,164,223]	4	hSpCas9	negative selection	6239206
10514276	10514299	19	+	27260156	EWS502	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.7179747405081072	[102]	[101,264,191,162]	9	hSpCas9	negative selection	6296201
10514373	10514396	19	+	27260156	EWS502	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.2743939160489655	[360]	[274,254,286,463]	-5	hSpCas9	negative selection	6296202
10514270	10514293	19	-	27260156	EWS502	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.4448796640225873	[192]	[350,252,258,237]	7	hSpCas9	negative selection	6296203
10513897	10513920	19	-	27260156	EWS502	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.5899498914115537	[38]	[87,51,34,70]	8	hSpCas9	negative selection	6360455
10514915	10514938	19	-	27260156	EWS502	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.4475049664872568	[131]	[185,162,160,257]	7	hSpCas9	negative selection	6360456
10513985	10514008	19	+	27260156	EWS502	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.7306689528963646	[185]	[268,403,358,274]	9	hSpCas9	negative selection	6360457
10514276	10514299	19	+	27260156	EW8	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.7452530414032184	[102]	[101,119,114,221]	9	hSpCas9	negative selection	6417452
10514373	10514396	19	+	27260156	EW8	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.11348527510077194	[360]	[414,250,234,201]	-2	hSpCas9	negative selection	6417453
10514270	10514293	19	-	27260156	EW8	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.8012283854194988	[192]	[277,361,162,305]	9	hSpCas9	negative selection	6417454
10513897	10513920	19	-	27260156	EW8	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-0.2337363886878565	[38]	[62,5,28,12]	-4	hSpCas9	negative selection	6481706
10514915	10514938	19	-	27260156	EW8	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.6244836363378334	[131]	[203,109,183,161]	9	hSpCas9	negative selection	6481707
10513985	10514008	19	+	27260156	EW8	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.2928593819584322	[185]	[290,111,169,178]	5	hSpCas9	negative selection	6481708
10514276	10514299	19	+	27260156	CORL105	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.7810431860872322	[102]	[208,243,236,142]	9	hSpCas9	negative selection	6538703
10514373	10514396	19	+	27260156	CORL105	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.1492708252906903	[360]	[292,383,463,392]	-3	hSpCas9	negative selection	6538704
10514270	10514293	19	-	27260156	CORL105	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.579699376961151	[192]	[410,227,386,336]	9	hSpCas9	negative selection	6538705
10513897	10513920	19	-	27260156	CORL105	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-0.028543498107453047	[38]	[38,34,44,59]	0	hSpCas9	negative selection	6602957
10514915	10514938	19	-	27260156	CORL105	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-0.057508042641137846	[131]	[111,152,251,91]	-1	hSpCas9	negative selection	6602958
10513985	10514008	19	+	27260156	CORL105	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.42508342673423327	[185]	[246,364,326,232]	7	hSpCas9	negative selection	6602959
10514276	10514299	19	+	27260156	HS294T	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.6802301877985646	[102]	[92,55,56,42]	8	hSpCas9	negative selection	6659954
10514373	10514396	19	+	27260156	HS294T	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.245897542471533	[360]	[111,113,112,134]	-3	hSpCas9	negative selection	6659955
10514270	10514293	19	-	27260156	HS294T	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	1.002762105598801	[192]	[175,128,159,126]	9	hSpCas9	negative selection	6659956
10513897	10513920	19	-	27260156	HS294T	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.3361843896327037	[38]	[19,32,10,9]	4	hSpCas9	negative selection	6724208
10514915	10514938	19	-	27260156	HS294T	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.03075042268058925	[131]	[39,57,45,67]	0	hSpCas9	negative selection	6724209
10513985	10514008	19	+	27260156	HS294T	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.7355186935287432	[185]	[218,73,54,122]	8	hSpCas9	negative selection	6724210
10514276	10514299	19	+	27260156	HCC44	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.8984292477997873	[102]	[235,270,214,140]	9	hSpCas9	negative selection	6781205
10514373	10514396	19	+	27260156	HCC44	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.016873712744130243	[360]	[394,415,204,552]	0	hSpCas9	negative selection	6781206
10514270	10514293	19	-	27260156	HCC44	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.7963487921218051	[192]	[280,408,517,317]	9	hSpCas9	negative selection	6781207
10513897	10513920	19	-	27260156	HCC44	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.29903500038148056	[38]	[95,65,31,21]	5	hSpCas9	negative selection	6845459
10514915	10514938	19	-	27260156	HCC44	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.07849298946454031	[131]	[81,116,345,116]	1	hSpCas9	negative selection	6845460
10513985	10514008	19	+	27260156	HCC44	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	-0.05507954756967526	[185]	[267,146,206,200]	-1	hSpCas9	negative selection	6845461
10514276	10514299	19	+	27260156	G402	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	1.8078284756080938	[102]	[560,309,810,102]	9	hSpCas9	negative selection	6902456
10514373	10514396	19	+	27260156	G402	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.39916134666486586	[360]	[654,444,470,744]	5	hSpCas9	negative selection	6902457
10514270	10514293	19	-	27260156	G402	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	1.2609405335788364	[192]	[479,747,507,519]	9	hSpCas9	negative selection	6902458
10513897	10513920	19	-	27260156	G402	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-0.19998991522302356	[38]	[50,93,4,20]	-3	hSpCas9	negative selection	6966710
10514915	10514938	19	-	27260156	G402	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.10033385311465293	[131]	[246,143,239,72]	1	hSpCas9	negative selection	6966711
10513985	10514008	19	+	27260156	G402	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.26737018752337827	[185]	[490,187,226,214]	3	hSpCas9	negative selection	6966712
10514276	10514299	19	+	27260156	L33	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.5732040609500728	[102]	[146,48,101,183]	9	hSpCas9	negative selection	7023707
10514373	10514396	19	+	27260156	L33	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.22955538075591703	[360]	[284,130,166,360]	-5	hSpCas9	negative selection	7023708
10514270	10514293	19	-	27260156	L33	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.7480358384604968	[192]	[317,154,149,360]	9	hSpCas9	negative selection	7023709
10513897	10513920	19	-	27260156	L33	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-0.2710574175070031	[38]	[41,12,20,21]	-6	hSpCas9	negative selection	7087961
10514915	10514938	19	-	27260156	L33	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.40456962029879007	[131]	[187,56,127,167]	8	hSpCas9	negative selection	7087962
10513985	10514008	19	+	27260156	L33	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	-0.3082553202550258	[185]	[116,67,100,157]	-6	hSpCas9	negative selection	7087963
10514276	10514299	19	+	27260156	K562	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.94657279206053	[102]	[27,273,162,225]	9	hSpCas9	negative selection	7144958
10514373	10514396	19	+	27260156	K562	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.12366490701820243	[360]	[527,462,232,207]	1	hSpCas9	negative selection	7144959
10514270	10514293	19	-	27260156	K562	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.26777351867527743	[192]	[409,155,197,87]	3	hSpCas9	negative selection	7144960
10513897	10513920	19	-	27260156	K562	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-0.8318488115438623	[38]	[57,10,6,5]	-7	hSpCas9	negative selection	7209212
10514915	10514938	19	-	27260156	K562	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.30313135233431	[131]	[166,38,177,184]	4	hSpCas9	negative selection	7209213
10513985	10514008	19	+	27260156	K562	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	-0.23231285498490406	[185]	[61,302,99,102]	-3	hSpCas9	negative selection	7209214
10514276	10514299	19	+	27260156	HT29	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.7550837645162396	[102]	[242,183,251,169]	9	hSpCas9	negative selection	7266209
10514373	10514396	19	+	27260156	HT29	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.13616359565653013	[360]	[570,613,377,391]	2	hSpCas9	negative selection	7266210
10514270	10514293	19	-	27260156	HT29	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.14535871498353514	[192]	[313,281,265,188]	3	hSpCas9	negative selection	7266211
10513897	10513920	19	-	27260156	HT29	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-0.18698876604155767	[38]	[47,86,23,14]	-4	hSpCas9	negative selection	7330463
10514915	10514938	19	-	27260156	HT29	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-0.41081379775353066	[131]	[75,173,84,144]	-6	hSpCas9	negative selection	7330464
10513985	10514008	19	+	27260156	HT29	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.34852525255966205	[185]	[257,320,327,247]	6	hSpCas9	negative selection	7330465
10514276	10514299	19	+	27260156	MHHES1	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.7210518094621363	[102]	[177,286,217,105]	9	hSpCas9	negative selection	7387460
10514373	10514396	19	+	27260156	MHHES1	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.014988517669897283	[360]	[549,409,372,307]	0	hSpCas9	negative selection	7387461
10514270	10514293	19	-	27260156	MHHES1	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.6644931032117665	[192]	[217,406,409,329]	9	hSpCas9	negative selection	7387462
10513897	10513920	19	-	27260156	MHHES1	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-1.2553096044146344	[38]	[16,9,45,2]	-9	hSpCas9	negative selection	7451714
10514915	10514938	19	-	27260156	MHHES1	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-0.47196141682249926	[131]	[124,115,135,62]	-7	hSpCas9	negative selection	7451715
10513985	10514008	19	+	27260156	MHHES1	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	-0.13932295022122698	[185]	[149,274,175,164]	-3	hSpCas9	negative selection	7451716
10514276	10514299	19	+	27260156	MEWO	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.6394428832794155	[102]	[219,114,128]	9	hSpCas9	negative selection	7508711
10514373	10514396	19	+	27260156	MEWO	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.06066306396512561	[360]	[384,350,326]	1	hSpCas9	negative selection	7508712
10514270	10514293	19	-	27260156	MEWO	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.3509718369908438	[192]	[236,256,197]	7	hSpCas9	negative selection	7508713
10513897	10513920	19	-	27260156	MEWO	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.07759935103817828	[38]	[66,42,10]	1	hSpCas9	negative selection	7572965
10514915	10514938	19	-	27260156	MEWO	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.3952582618684066	[131]	[192,190,108]	8	hSpCas9	negative selection	7572966
10513985	10514008	19	+	27260156	MEWO	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.22561670122254562	[185]	[305,250,72]	5	hSpCas9	negative selection	7572967
10514276	10514299	19	+	27260156	LNCAPCLONEFGC	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.4424071090623827	[102]	[72,123,171,145]	7	hSpCas9	negative selection	7629962
10514373	10514396	19	+	27260156	LNCAPCLONEFGC	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.15682810098074387	[360]	[355,252,380,477]	2	hSpCas9	negative selection	7629963
10514270	10514293	19	-	27260156	LNCAPCLONEFGC	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.5941341470983408	[192]	[272,249,322,218]	8	hSpCas9	negative selection	7629964
10513897	10513920	19	-	27260156	LNCAPCLONEFGC	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-0.11465992718148588	[38]	[6,19,53,53]	-2	hSpCas9	negative selection	7694216
10514915	10514938	19	-	27260156	LNCAPCLONEFGC	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-0.0015711915763771955	[131]	[141,51,208,91]	0	hSpCas9	negative selection	7694217
10513985	10514008	19	+	27260156	LNCAPCLONEFGC	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.5726141415634339	[185]	[382,134,329,170]	8	hSpCas9	negative selection	7694218
10514276	10514299	19	+	27260156	PANC0327	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.9167156675229928	[102]	[289,51,156,216]	9	hSpCas9	negative selection	7751213
10514373	10514396	19	+	27260156	PANC0327	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.2796200759431368	[360]	[229,224,332,270]	-4	hSpCas9	negative selection	7751214
10514270	10514293	19	-	27260156	PANC0327	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.5382768637284524	[192]	[194,321,248,215]	7	hSpCas9	negative selection	7751215
10513897	10513920	19	-	27260156	PANC0327	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.21082186722107332	[38]	[8,23,96,29]	3	hSpCas9	negative selection	7815467
10514915	10514938	19	-	27260156	PANC0327	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.01329133496105972	[131]	[300,42,79,73]	0	hSpCas9	negative selection	7815468
10513985	10514008	19	+	27260156	PANC0327	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.40592729083828405	[185]	[191,266,136,270]	6	hSpCas9	negative selection	7815469
10514276	10514299	19	+	27260156	NCIH2009	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.8003838546694806	[102]	[267,243,242]	9	hSpCas9	negative selection	7872464
10514373	10514396	19	+	27260156	NCIH2009	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.051879164106839015	[360]	[394,527,516]	0	hSpCas9	negative selection	7872465
10514270	10514293	19	-	27260156	NCIH2009	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	1.1221204549603996	[192]	[641,625,501]	9	hSpCas9	negative selection	7872466
10513897	10513920	19	-	27260156	NCIH2009	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.869412883128112	[38]	[102,52,143]	9	hSpCas9	negative selection	7936718
10514915	10514938	19	-	27260156	NCIH2009	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.055136054981037796	[131]	[219,252,105]	0	hSpCas9	negative selection	7936719
10513985	10514008	19	+	27260156	NCIH2009	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.7857872697506019	[185]	[379,440,508]	9	hSpCas9	negative selection	7936720
10514276	10514299	19	+	27260156	NCIH1373	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.9533656881477097	[102]	[378,183,219,34]	8	hSpCas9	negative selection	7993715
10514373	10514396	19	+	27260156	NCIH1373	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.5608850069471727	[360]	[337,230,179,96]	-5	hSpCas9	negative selection	7993716
10514270	10514293	19	-	27260156	NCIH1373	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	1.148467304126301	[192]	[481,433,499,132]	9	hSpCas9	negative selection	7993717
10513897	10513920	19	-	27260156	NCIH1373	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	1.3937873912724004	[38]	[61,206,82,22]	9	hSpCas9	negative selection	8057969
10514915	10514938	19	-	27260156	NCIH1373	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.9822516496907896	[131]	[321,492,141,49]	8	hSpCas9	negative selection	8057970
10513985	10514008	19	+	27260156	NCIH1373	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.3556268032016783	[185]	[418,285,125,67]	3	hSpCas9	negative selection	8057971
10514276	10514299	19	+	27260156	PATU8902	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.38781563578747047	[102]	[171,223,93,296]	4	hSpCas9	negative selection	8114966
10514373	10514396	19	+	27260156	PATU8902	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.42670209775653734	[360]	[449,728,923,513]	4	hSpCas9	negative selection	8114967
10514270	10514293	19	-	27260156	PATU8902	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.9520628794869682	[192]	[624,694,195,659]	8	hSpCas9	negative selection	8114968
10513897	10513920	19	-	27260156	PATU8902	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-1.426529613169568	[38]	[2,30,35,4]	-8	hSpCas9	negative selection	8179220
10514915	10514938	19	-	27260156	PATU8902	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-1.0033456193599652	[131]	[62,51,150,83]	-7	hSpCas9	negative selection	8179221
10513985	10514008	19	+	27260156	PATU8902	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.5878479845814157	[185]	[436,228,323,605]	6	hSpCas9	negative selection	8179222
10514276	10514299	19	+	27260156	PANC1	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.8811904663371046	[102]	[106,294,164,117]	9	hSpCas9	negative selection	8236217
10514373	10514396	19	+	27260156	PANC1	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.16752198655016165	[360]	[273,461,380,302]	2	hSpCas9	negative selection	8236218
10514270	10514293	19	-	27260156	PANC1	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.983536057632994	[192]	[361,353,452,168]	9	hSpCas9	negative selection	8236219
10513897	10513920	19	-	27260156	PANC1	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-0.48591259835869227	[38]	[5,11,74,3]	-6	hSpCas9	negative selection	8300471
10514915	10514938	19	-	27260156	PANC1	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.5987436630115095	[131]	[107,385,92,145]	8	hSpCas9	negative selection	8300472
10513985	10514008	19	+	27260156	PANC1	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.09341296819297495	[185]	[127,267,135,167]	1	hSpCas9	negative selection	8300473
10514276	10514299	19	+	27260156	PANC0813	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.31160347445093484	[102]	[180,98,183,139]	5	hSpCas9	negative selection	8357468
10514373	10514396	19	+	27260156	PANC0813	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.0880872805597549	[360]	[476,538,387,402]	1	hSpCas9	negative selection	8357469
10514270	10514293	19	-	27260156	PANC0813	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.799520534369892	[192]	[358,439,426,350]	9	hSpCas9	negative selection	8357470
10513897	10513920	19	-	27260156	PANC0813	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.06091531529648986	[38]	[65,84,19,22]	1	hSpCas9	negative selection	8421722
10514915	10514938	19	-	27260156	PANC0813	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-0.07411098690424933	[131]	[178,140,128,142]	-1	hSpCas9	negative selection	8421723
10513985	10514008	19	+	27260156	PANC0813	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	-0.28435864188702054	[185]	[171,160,122,255]	-4	hSpCas9	negative selection	8421724
10514276	10514299	19	+	27260156	RDES	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	1.0620506369136726	[102]	[231,201,260,302]	9	hSpCas9	negative selection	8478719
10514373	10514396	19	+	27260156	RDES	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.15143539168402642	[360]	[405,378,495,589]	2	hSpCas9	negative selection	8478720
10514270	10514293	19	-	27260156	RDES	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.54462974436298	[192]	[226,338,270,491]	8	hSpCas9	negative selection	8478721
10513897	10513920	19	-	27260156	RDES	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.28289329716915157	[38]	[40,75,52,45]	4	hSpCas9	negative selection	8542973
10514915	10514938	19	-	27260156	RDES	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.08659993086640849	[131]	[147,115,167,224]	1	hSpCas9	negative selection	8542974
10513985	10514008	19	+	27260156	RDES	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.3265656038203142	[185]	[200,225,244,436]	5	hSpCas9	negative selection	8542975
10514276	10514299	19	+	27260156	PC3	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.31126273111839176	[102]	[110,62,359,57]	6	hSpCas9	negative selection	8599970
10514373	10514396	19	+	27260156	PC3	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.37523221293579817	[360]	[153,312,400,318]	-7	hSpCas9	negative selection	8599971
10514270	10514293	19	-	27260156	PC3	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.4448679584002212	[192]	[212,265,337,247]	8	hSpCas9	negative selection	8599972
10513897	10513920	19	-	27260156	PC3	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.4396445813649352	[38]	[21,28,18,142]	8	hSpCas9	negative selection	8664224
10514915	10514938	19	-	27260156	PC3	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.3203111088865076	[131]	[128,90,217,243]	6	hSpCas9	negative selection	8664225
10513985	10514008	19	+	27260156	PC3	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.40100335734353887	[185]	[209,282,239,223]	8	hSpCas9	negative selection	8664226
10514276	10514299	19	+	27260156	PATU8988T	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.8964027370985044	[102]	[266,142,60,274]	9	hSpCas9	negative selection	8721221
10514373	10514396	19	+	27260156	PATU8988T	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.22963990180457813	[360]	[490,364,420,349]	4	hSpCas9	negative selection	8721222
10514270	10514293	19	-	27260156	PATU8988T	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.3903343278514807	[192]	[220,249,320,179]	6	hSpCas9	negative selection	8721223
10513897	10513920	19	-	27260156	PATU8988T	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-0.45595900097892805	[38]	[1,29,67,7]	-6	hSpCas9	negative selection	8785475
10514915	10514938	19	-	27260156	PATU8988T	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.2027164156070056	[131]	[139,228,67,159]	3	hSpCas9	negative selection	8785476
10513985	10514008	19	+	27260156	PATU8988T	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.5549712143230565	[185]	[218,78,345,404]	8	hSpCas9	negative selection	8785477
10514276	10514299	19	+	27260156	T47D	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.6808589061497201	[102]	[209,181,174,203]	9	hSpCas9	negative selection	8842472
10514373	10514396	19	+	27260156	T47D	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.04679319940431126	[360]	[411,316,454,452]	-1	hSpCas9	negative selection	8842473
10514270	10514293	19	-	27260156	T47D	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.4682772081895862	[192]	[372,313,249,307]	8	hSpCas9	negative selection	8842474
10513897	10513920	19	-	27260156	T47D	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.4002468854369692	[38]	[73,42,49,74]	8	hSpCas9	negative selection	8906726
10514915	10514938	19	-	27260156	T47D	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.16956770229019158	[131]	[204,110,141,241]	3	hSpCas9	negative selection	8906727
10513985	10514008	19	+	27260156	T47D	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.31533995047051677	[185]	[278,250,257,292]	6	hSpCas9	negative selection	8906728
10514276	10514299	19	+	27260156	SU8686	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.9296573816075442	[102]	[252,146,135,246]	9	hSpCas9	negative selection	8963723
10514373	10514396	19	+	27260156	SU8686	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.285081094938987	[360]	[404,369,447,548]	5	hSpCas9	negative selection	8963724
10514270	10514293	19	-	27260156	SU8686	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	1.1294428150341183	[192]	[377,359,316,665]	9	hSpCas9	negative selection	8963725
10513897	10513920	19	-	27260156	SU8686	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	-0.24000678803145314	[38]	[15,37,34,44]	-4	hSpCas9	negative selection	9027977
10514915	10514938	19	-	27260156	SU8686	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.33160673352497705	[131]	[164,165,81,256]	5	hSpCas9	negative selection	9027978
10513985	10514008	19	+	27260156	SU8686	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.4355797696960855	[185]	[188,203,281,350]	7	hSpCas9	negative selection	9027979
10514276	10514299	19	+	27260156	SKES1	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.16611153568142	[102]	[89,228,76,78]	3	hSpCas9	negative selection	9084974
10514373	10514396	19	+	27260156	SKES1	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.12894516782265297	[360]	[682,377,330,236]	3	hSpCas9	negative selection	9084975
10514270	10514293	19	-	27260156	SKES1	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.4421024528696441	[192]	[239,329,245,235]	8	hSpCas9	negative selection	9084976
10513897	10513920	19	-	27260156	SKES1	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.10189033964418392	[38]	[76,4,63,22]	2	hSpCas9	negative selection	9149228
10514915	10514938	19	-	27260156	SKES1	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.3496919779220755	[131]	[176,197,123,174]	7	hSpCas9	negative selection	9149229
10513985	10514008	19	+	27260156	SKES1	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.3054656846549968	[185]	[309,173,272,168]	6	hSpCas9	negative selection	9149230
10514276	10514299	19	+	27260156	TOV112D	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.7482353499892351	[102]	[127,171,80,303]	9	hSpCas9	negative selection	9206225
10514373	10514396	19	+	27260156	TOV112D	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.34205230334906495	[360]	[242,368,167,374]	-6	hSpCas9	negative selection	9206226
10514270	10514293	19	-	27260156	TOV112D	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.7464578229635388	[192]	[219,468,220,410]	9	hSpCas9	negative selection	9206227
10513897	10513920	19	-	27260156	TOV112D	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.045706350404164375	[38]	[56,46,46,13]	0	hSpCas9	negative selection	9270479
10514915	10514938	19	-	27260156	TOV112D	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.06661170725836096	[131]	[111,242,116,105]	1	hSpCas9	negative selection	9270480
10513985	10514008	19	+	27260156	TOV112D	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.32280550979109246	[185]	[222,198,324,176]	6	hSpCas9	negative selection	9270481
10514276	10514299	19	+	27260156	TC71	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.660716876856349	[102]	[207,130,134,227]	9	hSpCas9	negative selection	9327476
10514373	10514396	19	+	27260156	TC71	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	-0.3251206115556146	[360]	[380,230,290,332]	-7	hSpCas9	negative selection	9327477
10514270	10514293	19	-	27260156	TC71	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.4677514906526081	[192]	[359,277,209,297]	9	hSpCas9	negative selection	9327478
10513897	10513920	19	-	27260156	TC71	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.04760469578254556	[38]	[58,32,53,24]	1	hSpCas9	negative selection	9391730
10514915	10514938	19	-	27260156	TC71	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	0.2579921235444369	[131]	[179,178,180,133]	6	hSpCas9	negative selection	9391731
10513985	10514008	19	+	27260156	TC71	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	-0.014327336113121536	[185]	[245,203,175,160]	0	hSpCas9	negative selection	9391732
10514276	10514299	19	+	27260156	TC32	viability	AGCGCGGCTTGCGACGCGCCCGG	S1PR5	ENSG00000180739	0.9149653906965816	[102]	[142,100,205,317]	9	hSpCas9	negative selection	9448727
10514373	10514396	19	+	27260156	TC32	viability	CGCGTAGAGTGCACAGATAGCGG	S1PR5	ENSG00000180739	0.34170989305765503	[360]	[317,458,483,443]	6	hSpCas9	negative selection	9448728
10514270	10514293	19	-	27260156	TC32	viability	GCGTCGCAAGCCGCGCTCGCTGG	S1PR5	ENSG00000180739	0.6373836118772188	[192]	[191,257,233,448]	9	hSpCas9	negative selection	9448729
10513897	10513920	19	-	27260156	TC32	viability	CGCTCATCGCCCCAGCGCGACGG	S1PR5	ENSG00000180739	0.1384693978408138	[38]	[10,28,86,48]	2	hSpCas9	negative selection	9512981
10514915	10514938	19	-	27260156	TC32	viability	CCGCGGTGCGCGCTACCAGCCGG	S1PR5	ENSG00000180739	-0.1938730541563587	[131]	[127,54,155,114]	-4	hSpCas9	negative selection	9512982
10513985	10514008	19	+	27260156	TC32	viability	CAGCCGCGCTCGCCGACTGCTGG	S1PR5	ENSG00000180739	0.5323676420430105	[185]	[188,244,377,213]	8	hSpCas9	negative selection	9512983
10513933	10513956	19	+	27869803	HPAFII	viability after 27 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	-0.3111217921477901	[185]	[68,86,NaN]	-2	hSpCas9	negative selection	9565374
10514033	10514056	19	+	27869803	HPAFII	viability after 27 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.7525173832510765	[178]	[109,198,NaN]	6	hSpCas9	negative selection	9565375
10514246	10514269	19	-	27869803	HPAFII	viability after 27 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.3552761765254948	[97]	[54,74,NaN]	3	hSpCas9	negative selection	9565376
10514591	10514614	19	-	27869803	HPAFII	viability after 27 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	-0.3612976744447641	[254]	[165,52,NaN]	-3	hSpCas9	negative selection	9565377
10514625	10514648	19	+	27869803	HPAFII	viability after 27 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.8723648417637357	[91]	[51,118,NaN]	7	hSpCas9	negative selection	9565378
10513933	10513956	19	+	27869803	HPAFII	viability after 15 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	-0.9196198784497449	[185]	[35,148,NaN]	-7	hSpCas9	negative selection	9647823
10514033	10514056	19	+	27869803	HPAFII	viability after 15 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.2557703782286478	[178]	[151,277,NaN]	3	hSpCas9	negative selection	9647824
10514246	10514269	19	-	27869803	HPAFII	viability after 15 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.475498450300913	[97]	[233,91,NaN]	5	hSpCas9	negative selection	9647825
10514591	10514614	19	-	27869803	HPAFII	viability after 15 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	-0.18166751416851845	[254]	[388,149,NaN]	-2	hSpCas9	negative selection	9647826
10514625	10514648	19	+	27869803	HPAFII	viability after 15 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	-0.006960190905323627	[91]	[90,102,NaN]	0	hSpCas9	negative selection	9647827
10513933	10513956	19	+	27869803	ASPC1	viability after 36 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.20061927804448199	[325]	[282,60,77]	2	hSpCas9	negative selection	9730272
10514033	10514056	19	+	27869803	ASPC1	viability after 36 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.505997223982705	[499]	[235,269,235]	5	hSpCas9	negative selection	9730273
10514246	10514269	19	-	27869803	ASPC1	viability after 36 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.10832556335524923	[320]	[107,108,95]	-1	hSpCas9	negative selection	9730274
10514591	10514614	19	-	27869803	ASPC1	viability after 36 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	-0.02710972287350427	[753]	[351,242,201]	0	hSpCas9	negative selection	9730275
10514625	10514648	19	+	27869803	ASPC1	viability after 36 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	-0.3573749248820979	[291]	[68,80,84]	-4	hSpCas9	negative selection	9730276
10513933	10513956	19	+	27869803	PATU8988S	viability after 35 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.664820512239844	[343]	[283,154,NaN]	7	hSpCas9	negative selection	9812721
10514033	10514056	19	+	27869803	PATU8988S	viability after 35 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	-1.5806861590669516	[586]	[95,61,NaN]	-8	hSpCas9	negative selection	9812722
10514246	10514269	19	-	27869803	PATU8988S	viability after 35 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.8606305342064043	[209]	[187,118,NaN]	8	hSpCas9	negative selection	9812723
10514591	10514614	19	-	27869803	PATU8988S	viability after 35 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	0.6004887510694229	[582]	[362,348,NaN]	6	hSpCas9	negative selection	9812724
10514625	10514648	19	+	27869803	PATU8988S	viability after 35 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	-0.6933848035720211	[292]	[61,83,NaN]	-6	hSpCas9	negative selection	9812725
10513933	10513956	19	+	27869803	PATU8988S	viability after 31 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.2546192535610853	[343]	[182,138,NaN]	3	hSpCas9	negative selection	9895170
10514033	10514056	19	+	27869803	PATU8988S	viability after 31 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	-0.8115859459189069	[586]	[124,143,NaN]	-7	hSpCas9	negative selection	9895171
10514246	10514269	19	-	27869803	PATU8988S	viability after 31 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.7587860203377664	[209]	[175,97,NaN]	8	hSpCas9	negative selection	9895172
10514591	10514614	19	-	27869803	PATU8988S	viability after 31 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	0.3743750051836926	[582]	[215,409,NaN]	4	hSpCas9	negative selection	9895173
10514625	10514648	19	+	27869803	PATU8988S	viability after 31 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	-0.7750652523994357	[292]	[29,116,NaN]	-7	hSpCas9	negative selection	9895174
10513933	10513956	19	+	27869803	HPAFII	viability after 35 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	-0.10543560516894157	[185]	[79,95,NaN]	0	hSpCas9	negative selection	9977619
10514033	10514056	19	+	27869803	HPAFII	viability after 35 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.7414279394392526	[178]	[87,222,NaN]	5	hSpCas9	negative selection	9977620
10514246	10514269	19	-	27869803	HPAFII	viability after 35 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	0.10921869812080032	[97]	[21,88,NaN]	0	hSpCas9	negative selection	9977621
10514591	10514614	19	-	27869803	HPAFII	viability after 35 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	0.026068574067879366	[254]	[201,51,NaN]	0	hSpCas9	negative selection	9977622
10514625	10514648	19	+	27869803	HPAFII	viability after 35 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.967824370809448	[91]	[44,142,NaN]	6	hSpCas9	negative selection	9977623
10513933	10513956	19	+	27869803	HPAFII	viability after 31 days	AAGCTCCCATCAAGGCCCGGGGG	S1PR5	ENSG00000180739	0.40019570437912	[185]	[109,167,NaN]	3	hSpCas9	negative selection	10060068
10514033	10514056	19	+	27869803	HPAFII	viability after 31 days	AGTGGCGTCCGCAGCAGACCAGG	S1PR5	ENSG00000180739	0.16461843960386874	[178]	[58,170,NaN]	1	hSpCas9	negative selection	10060069
10514246	10514269	19	-	27869803	HPAFII	viability after 31 days	CTTGCTGCGCACGCTCAGCGTGG	S1PR5	ENSG00000180739	-0.21975065209260314	[97]	[29,65,NaN]	-1	hSpCas9	negative selection	10060070
10514591	10514614	19	-	27869803	HPAFII	viability after 31 days	CAGCCTCACCATGGCGCGCAGGG	S1PR5	ENSG00000180739	-0.5393489541504926	[254]	[108,86,NaN]	-4	hSpCas9	negative selection	10060071
10514625	10514648	19	+	27869803	HPAFII	viability after 31 days	GATGGCCAGGAGGCTCAGCACGG	S1PR5	ENSG00000180739	0.8740131841726038	[91]	[63,127,NaN]	6	hSpCas9	negative selection	10060072
10514607	10514630	19	+	28162770	P31FUJ	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-0.4061338072999403	[52]	[46]	-4	hSpCas9	negative selection	10229484
10514421	10514444	19	+	28162770	P31FUJ	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.30890709835289376	[157]	[229]	3	hSpCas9	negative selection	10229485
10514592	10514615	19	-	28162770	P31FUJ	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.6470652174275933	[193]	[356]	7	hSpCas9	negative selection	10229486
10514214	10514237	19	+	28162770	P31FUJ	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	-0.7753294388151384	[66]	[45]	-6	hSpCas9	negative selection	10229487
10514106	10514129	19	+	28162770	P31FUJ	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	-0.7036171606584694	[333]	[240]	-5	hSpCas9	negative selection	10229488
10514801	10514824	19	+	28162770	P31FUJ	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	0.4320136039959923	[40]	[64]	5	hSpCas9	negative selection	10229489
10514674	10514697	19	-	28162770	P31FUJ	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-0.36086724320267344	[258]	[236]	-3	hSpCas9	negative selection	10229490
10514618	10514641	19	-	28162770	P31FUJ	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	0.578295119329042	[109]	[192]	6	hSpCas9	negative selection	10229491
10514517	10514540	19	+	28162770	P31FUJ	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.2517398051624187	[232]	[325]	2	hSpCas9	negative selection	10229492
10514485	10514508	19	+	28162770	P31FUJ	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	-0.4321110126377854	[30]	[26]	-4	hSpCas9	negative selection	10229493
10514607	10514630	19	+	28162770	TF1	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10398850
10514421	10514444	19	+	28162770	TF1	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	NaN	[NaN]	[309]	1	hSpCas9	negative selection	10398851
10514592	10514615	19	-	28162770	TF1	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	NaN	[NaN]	[345]	1	hSpCas9	negative selection	10398852
10514214	10514237	19	+	28162770	TF1	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10398853
10514106	10514129	19	+	28162770	TF1	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10398854
10514801	10514824	19	+	28162770	TF1	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10398855
10514674	10514697	19	-	28162770	TF1	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10398856
10514618	10514641	19	-	28162770	TF1	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10398857
10514517	10514540	19	+	28162770	TF1	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	NaN	[NaN]	[272]	1	hSpCas9	negative selection	10398858
10514485	10514508	19	+	28162770	TF1	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10398859
10514607	10514630	19	+	28162770	SKM1	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-1.0335058032157174	[21]	[18]	-6	hSpCas9	negative selection	10568216
10514421	10514444	19	+	28162770	SKM1	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.41615803917275906	[38]	[91]	4	hSpCas9	negative selection	10568217
10514592	10514615	19	-	28162770	SKM1	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.2184125704239026	[87]	[180]	2	hSpCas9	negative selection	10568218
10514214	10514237	19	+	28162770	SKM1	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	-0.2814333166593026	[21]	[31]	-2	hSpCas9	negative selection	10568219
10514106	10514129	19	+	28162770	SKM1	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	-0.09763614063543286	[68]	[113]	-1	hSpCas9	negative selection	10568220
10514801	10514824	19	+	28162770	SKM1	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	0.04049477822805958	[10]	[19]	0	hSpCas9	negative selection	10568221
10514674	10514697	19	-	28162770	SKM1	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-1.7606011533578623	[68]	[35]	-8	hSpCas9	negative selection	10568222
10514618	10514641	19	-	28162770	SKM1	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	-0.09330371983939978	[34]	[57]	-1	hSpCas9	negative selection	10568223
10514517	10514540	19	+	28162770	SKM1	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.35046549798275994	[62]	[141]	3	hSpCas9	negative selection	10568224
10514485	10514508	19	+	28162770	SKM1	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	-0.1699250014423126	[6]	[10]	-1	hSpCas9	negative selection	10568225
10514607	10514630	19	+	28162770	SKM1	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-1.0335058032157174	[21]	[18]	-6	hSpCas9	negative selection	10737582
10514421	10514444	19	+	28162770	SKM1	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.41615803917275906	[38]	[91]	4	hSpCas9	negative selection	10737583
10514592	10514615	19	-	28162770	SKM1	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.2184125704239026	[87]	[180]	2	hSpCas9	negative selection	10737584
10514214	10514237	19	+	28162770	SKM1	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	-0.2814333166593026	[21]	[31]	-2	hSpCas9	negative selection	10737585
10514106	10514129	19	+	28162770	SKM1	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	-0.09763614063543286	[68]	[113]	-1	hSpCas9	negative selection	10737586
10514801	10514824	19	+	28162770	SKM1	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	0.04049477822805958	[10]	[19]	0	hSpCas9	negative selection	10737587
10514674	10514697	19	-	28162770	SKM1	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-1.7606011533578623	[68]	[35]	-8	hSpCas9	negative selection	10737588
10514618	10514641	19	-	28162770	SKM1	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	-0.09330371983939978	[34]	[57]	-1	hSpCas9	negative selection	10737589
10514517	10514540	19	+	28162770	SKM1	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.35046549798275994	[62]	[141]	3	hSpCas9	negative selection	10737590
10514485	10514508	19	+	28162770	SKM1	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	-0.1699250014423126	[6]	[10]	-1	hSpCas9	negative selection	10737591
10514607	10514630	19	+	28162770	PL21	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	0.5027023845097514	[59]	[36]	4	hSpCas9	negative selection	10906948
10514421	10514444	19	+	28162770	PL21	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.317272248087318	[200]	[108]	3	hSpCas9	negative selection	10906949
10514592	10514615	19	-	28162770	PL21	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.5447877858767659	[251]	[159]	5	hSpCas9	negative selection	10906950
10514214	10514237	19	+	28162770	PL21	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	2.525715486391827	[78]	[197]	9	hSpCas9	negative selection	10906951
10514106	10514129	19	+	28162770	PL21	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	-0.009313751139629622	[295]	[127]	0	hSpCas9	negative selection	10906952
10514801	10514824	19	+	28162770	PL21	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	1.4971213522464515	[34]	[42]	9	hSpCas9	negative selection	10906953
10514674	10514697	19	-	28162770	PL21	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	0.425431926331563	[141]	[82]	4	hSpCas9	negative selection	10906954
10514618	10514641	19	-	28162770	PL21	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	1.0836256057628948	[115]	[106]	8	hSpCas9	negative selection	10906955
10514517	10514540	19	+	28162770	PL21	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.25018029698891564	[169]	[87]	2	hSpCas9	negative selection	10906956
10514485	10514508	19	+	28162770	PL21	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	1.4095929801182696	[31]	[36]	9	hSpCas9	negative selection	10906957
10514607	10514630	19	+	28162770	P31FUJ	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-0.4061338072999403	[52]	[46]	-4	hSpCas9	negative selection	11076314
10514421	10514444	19	+	28162770	P31FUJ	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.30890709835289376	[157]	[229]	3	hSpCas9	negative selection	11076315
10514592	10514615	19	-	28162770	P31FUJ	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.6470652174275933	[193]	[356]	7	hSpCas9	negative selection	11076316
10514214	10514237	19	+	28162770	P31FUJ	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	-0.7753294388151384	[66]	[45]	-6	hSpCas9	negative selection	11076317
10514106	10514129	19	+	28162770	P31FUJ	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	-0.7036171606584694	[333]	[240]	-5	hSpCas9	negative selection	11076318
10514801	10514824	19	+	28162770	P31FUJ	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	0.4320136039959923	[40]	[64]	5	hSpCas9	negative selection	11076319
10514674	10514697	19	-	28162770	P31FUJ	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-0.36086724320267344	[258]	[236]	-3	hSpCas9	negative selection	11076320
10514618	10514641	19	-	28162770	P31FUJ	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	0.578295119329042	[109]	[192]	6	hSpCas9	negative selection	11076321
10514517	10514540	19	+	28162770	P31FUJ	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.2517398051624187	[232]	[325]	2	hSpCas9	negative selection	11076322
10514485	10514508	19	+	28162770	P31FUJ	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	-0.4321110126377854	[30]	[26]	-4	hSpCas9	negative selection	11076323
10514607	10514630	19	+	28162770	OCIAML5	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-1.0585174483314232	[29]	[25]	-6	hSpCas9	negative selection	11245680
10514421	10514444	19	+	28162770	OCIAML5	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.7809902180582041	[117]	[365]	6	hSpCas9	negative selection	11245681
10514592	10514615	19	-	28162770	OCIAML5	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	1.2830930124176387	[111]	[491]	9	hSpCas9	negative selection	11245682
10514214	10514237	19	+	28162770	OCIAML5	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	1.0768503310745203	[25]	[98]	8	hSpCas9	negative selection	11245683
10514106	10514129	19	+	28162770	OCIAML5	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	-0.20121613448638379	[106]	[167]	-1	hSpCas9	negative selection	11245684
10514801	10514824	19	+	28162770	OCIAML5	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	-1.0635706760577088	[21]	[18]	-6	hSpCas9	negative selection	11245685
10514674	10514697	19	-	28162770	OCIAML5	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-0.6278514139207314	[112]	[131]	-4	hSpCas9	negative selection	11245686
10514618	10514641	19	-	28162770	OCIAML5	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	-1.3811758368516356	[113]	[78]	-7	hSpCas9	negative selection	11245687
10514517	10514540	19	+	28162770	OCIAML5	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.20197326884889225	[130]	[271]	1	hSpCas9	negative selection	11245688
10514485	10514508	19	+	28162770	OCIAML5	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	-0.852066570863997	[32]	[32]	-5	hSpCas9	negative selection	11245689
10514607	10514630	19	+	28162770	EOL1	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-0.6256493109899453	[122]	[41]	-4	hSpCas9	negative selection	11415046
10514421	10514444	19	+	28162770	EOL1	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	1.2073906584845087	[216]	[263]	8	hSpCas9	negative selection	11415047
10514592	10514615	19	-	28162770	EOL1	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.6287038059866397	[506]	[412]	5	hSpCas9	negative selection	11415048
10514214	10514237	19	+	28162770	EOL1	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	0.3168651943492947	[159]	[104]	3	hSpCas9	negative selection	11415049
10514106	10514129	19	+	28162770	EOL1	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	0.12151100610661958	[416]	[238]	1	hSpCas9	negative selection	11415050
10514801	10514824	19	+	28162770	EOL1	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	1.6148632724379195	[43]	[70]	9	hSpCas9	negative selection	11415051
10514674	10514697	19	-	28162770	EOL1	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-1.6604147291506215	[203]	[33]	-8	hSpCas9	negative selection	11415052
10514618	10514641	19	-	28162770	EOL1	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	0.2371380018785607	[123]	[76]	2	hSpCas9	negative selection	11415053
10514517	10514540	19	+	28162770	EOL1	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	1.1313601814395242	[265]	[306]	8	hSpCas9	negative selection	11415054
10514485	10514508	19	+	28162770	EOL1	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	-2.0754522284294654	[31]	[3]	-8	hSpCas9	negative selection	11415055
10514607	10514630	19	+	28162770	MOLM13	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	1.553465113250653	[89]	[190]	9	hSpCas9	negative selection	11584412
10514421	10514444	19	+	28162770	MOLM13	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	-0.5082638765010534	[239]	[121]	-3	hSpCas9	negative selection	11584413
10514592	10514615	19	-	28162770	MOLM13	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.8819749210126444	[378]	[504]	6	hSpCas9	negative selection	11584414
10514214	10514237	19	+	28162770	MOLM13	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	2.1001575970440918	[99]	[309]	9	hSpCas9	negative selection	11584415
10514106	10514129	19	+	28162770	MOLM13	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	-0.2151832046264252	[288]	[179]	-1	hSpCas9	negative selection	11584416
10514801	10514824	19	+	28162770	MOLM13	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	1.29385998176953	[21]	[38]	8	hSpCas9	negative selection	11584417
10514674	10514697	19	-	28162770	MOLM13	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-2.273577604856568	[320]	[47]	-8	hSpCas9	negative selection	11584418
10514618	10514641	19	-	28162770	MOLM13	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	-0.33006684251077567	[152]	[87]	-2	hSpCas9	negative selection	11584419
10514517	10514540	19	+	28162770	MOLM13	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.40347265304880836	[228]	[218]	3	hSpCas9	negative selection	11584420
10514485	10514508	19	+	28162770	MOLM13	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	-1.8051291128618367	[28]	[5]	-7	hSpCas9	negative selection	11584421
10514607	10514630	19	+	28162770	HEL	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-0.9422236687207992	[77]	[25]	-5	hSpCas9	negative selection	11753778
10514421	10514444	19	+	28162770	HEL	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.4468186220251001	[188]	[164]	4	hSpCas9	negative selection	11753779
10514592	10514615	19	-	28162770	HEL	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.5175970787228732	[336]	[308]	4	hSpCas9	negative selection	11753780
10514214	10514237	19	+	28162770	HEL	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	-0.4417946782113107	[122]	[57]	-3	hSpCas9	negative selection	11753781
10514106	10514129	19	+	28162770	HEL	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	0.1007695490475112	[280]	[192]	0	hSpCas9	negative selection	11753782
10514801	10514824	19	+	28162770	HEL	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	-0.017774701727975906	[48]	[30]	0	hSpCas9	negative selection	11753783
10514674	10514697	19	-	28162770	HEL	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-2.3319944093892127	[282]	[35]	-8	hSpCas9	negative selection	11753784
10514618	10514641	19	-	28162770	HEL	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	0.7026102879777556	[117]	[122]	6	hSpCas9	negative selection	11753785
10514517	10514540	19	+	28162770	HEL	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	-0.08629984639422038	[241]	[145]	0	hSpCas9	negative selection	11753786
10514485	10514508	19	+	28162770	HEL	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	-1.9422236687207994	[35]	[5]	-8	hSpCas9	negative selection	11753787
10514607	10514630	19	+	28162770	MV411	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-0.36553932610797735	[103]	[67]	-3	hSpCas9	negative selection	11923144
10514421	10514444	19	+	28162770	MV411	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.07971010504470886	[163]	[145]	0	hSpCas9	negative selection	11923145
10514592	10514615	19	-	28162770	MV411	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.44987536574357834	[311]	[358]	4	hSpCas9	negative selection	11923146
10514214	10514237	19	+	28162770	MV411	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	-0.9452075271596203	[95]	[41]	-6	hSpCas9	negative selection	11923147
10514106	10514129	19	+	28162770	MV411	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	-1.3047350148207113	[260]	[88]	-7	hSpCas9	negative selection	11923148
10514801	10514824	19	+	28162770	MV411	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	-5.110114453835308	[40]	[0]	-9	hSpCas9	negative selection	11923149
10514674	10514697	19	-	28162770	MV411	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-1.039844401297696	[143]	[58]	-6	hSpCas9	negative selection	11923150
10514618	10514641	19	-	28162770	MV411	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	0.33282904201342	[81]	[86]	3	hSpCas9	negative selection	11923151
10514517	10514540	19	+	28162770	MV411	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.26383198903344385	[174]	[176]	2	hSpCas9	negative selection	11923152
10514485	10514508	19	+	28162770	MV411	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	-2.415527461939654	[18]	[2]	-8	hSpCas9	negative selection	11923153
10514607	10514630	19	+	28162770	MONOMAC1	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-0.2547523449158411	[50]	[48]	-2	hSpCas9	negative selection	12092510
10514421	10514444	19	+	28162770	MONOMAC1	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.9209603623388978	[87]	[190]	8	hSpCas9	negative selection	12092511
10514592	10514615	19	-	28162770	MONOMAC1	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.31516931122628833	[182]	[260]	3	hSpCas9	negative selection	12092512
10514214	10514237	19	+	28162770	MONOMAC1	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	0.15844380753883514	[67]	[86]	1	hSpCas9	negative selection	12092513
10514106	10514129	19	+	28162770	MONOMAC1	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	0.18147477619417607	[159]	[207]	1	hSpCas9	negative selection	12092514
10514801	10514824	19	+	28162770	MONOMAC1	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	-1.6918015388091316	[30]	[10]	-8	hSpCas9	negative selection	12092515
10514674	10514697	19	-	28162770	MONOMAC1	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-1.031613237852182	[106]	[59]	-7	hSpCas9	negative selection	12092516
10514618	10514641	19	-	28162770	MONOMAC1	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	-0.9829120417067061	[49]	[28]	-7	hSpCas9	negative selection	12092517
10514517	10514540	19	+	28162770	MONOMAC1	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.5451653954727995	[164]	[275]	5	hSpCas9	negative selection	12092518
10514485	10514508	19	+	28162770	MONOMAC1	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	0.8029631529404462	[4]	[9]	7	hSpCas9	negative selection	12092519
10514607	10514630	19	+	28162770	OCIAML2	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-0.3237884369128905	[13]	[61]	-3	hSpCas9	negative selection	12261876
10514421	10514444	19	+	28162770	OCIAML2	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	-0.011198206604863925	[25]	[142]	0	hSpCas9	negative selection	12261877
10514592	10514615	19	-	28162770	OCIAML2	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.5568509111799458	[38]	[317]	5	hSpCas9	negative selection	12261878
10514214	10514237	19	+	28162770	OCIAML2	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	-0.511271809739507	[17]	[69]	-4	hSpCas9	negative selection	12261879
10514106	10514129	19	+	28162770	OCIAML2	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	0.6029513071389462	[42]	[361]	6	hSpCas9	negative selection	12261880
10514801	10514824	19	+	28162770	OCIAML2	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	-1.760136442437146	[10]	[17]	-8	hSpCas9	negative selection	12261881
10514674	10514697	19	-	28162770	OCIAML2	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-1.2482374039057131	[26]	[62]	-7	hSpCas9	negative selection	12261882
10514618	10514641	19	-	28162770	OCIAML2	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	-0.25912572004844947	[18]	[87]	-2	hSpCas9	negative selection	12261883
10514517	10514540	19	+	28162770	OCIAML2	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	0.7285258875239056	[37]	[348]	7	hSpCas9	negative selection	12261884
10514485	10514508	19	+	28162770	OCIAML2	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	0.20744207987047636	[4]	[31]	2	hSpCas9	negative selection	12261885
10514607	10514630	19	+	28162770	OCIAML3	viability	GAGGCTGCGCTCCAGCGCGATGG	S1PR5	ENSG00000180739	-0.3209891459177474	[23]	[57]	-3	hSpCas9	negative selection	12431242
10514421	10514444	19	+	28162770	OCIAML3	viability	GCAGAAGAGCACGTAGGCCTTGG	S1PR5	ENSG00000180739	0.4625758880422043	[24]	[103]	4	hSpCas9	negative selection	12431243
10514592	10514615	19	-	28162770	OCIAML3	viability	GCAGCCTCACCATGGCGCGCAGG	S1PR5	ENSG00000180739	0.4887327906837731	[71]	[304]	4	hSpCas9	negative selection	12431244
10514214	10514237	19	+	28162770	OCIAML3	viability	GGGGCCCCAACATGCCACAAAGG	S1PR5	ENSG00000180739	-0.25697265304659256	[18]	[47]	-2	hSpCas9	negative selection	12431245
10514106	10514129	19	+	28162770	OCIAML3	viability	GTTCAGAAGTGAGTTGGCCATGG	S1PR5	ENSG00000180739	0.21922384807011036	[69]	[245]	2	hSpCas9	negative selection	12431246
10514801	10514824	19	+	28162770	OCIAML3	viability	TGGGAGCGTGGAAGCGCGGGTGG	S1PR5	ENSG00000180739	0.8389517669519431	[4]	[26]	7	hSpCas9	negative selection	12431247
10514674	10514697	19	-	28162770	OCIAML3	viability	GCGCTCTGGTTCGCACGGGAGGG	S1PR5	ENSG00000180739	-0.40638063714839173	[53]	[122]	-3	hSpCas9	negative selection	12431248
10514618	10514641	19	-	28162770	OCIAML3	viability	GAGCCTCCTGGCCATCGCGCTGG	S1PR5	ENSG00000180739	0.02748073642210702	[25]	[79]	0	hSpCas9	negative selection	12431249
10514517	10514540	19	+	28162770	OCIAML3	viability	GAGGAGCAGCGACACGCCCCAGG	S1PR5	ENSG00000180739	-0.5693455860898939	[57]	[117]	-4	hSpCas9	negative selection	12431250
10514485	10514508	19	+	28162770	OCIAML3	viability	AGGCAATTCCAGCCCAGCGCTGG	S1PR5	ENSG00000180739	-0.700922844240675	[6]	[12]	-5	hSpCas9	negative selection	12431251