Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:60485
• Symbol:SAV1
• Description:salvador family WW domain containing protein 1

DataSource: http://genomecrispr.dkfz.de/#!/results/SAV1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
50667864	50667887	14	+	26472758	Jiyoye	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.9565139724963083	[163]	[239]	6	hSpCas9	negative selection	142403
50644939	50644962	14	-	26472758	Jiyoye	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	-0.30248286666459734	[627]	[383]	-2	hSpCas9	negative selection	142404
50644819	50644842	14	+	26472758	Jiyoye	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.16558939493611458	[226]	[191]	1	hSpCas9	negative selection	142405
50640867	50640890	14	+	26472758	Jiyoye	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.6600957095754699	[166]	[198]	5	hSpCas9	negative selection	142406
50640852	50640875	14	+	26472758	Jiyoye	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	-0.2426382635652508	[90]	[57]	-2	hSpCas9	negative selection	142407
50644911	50644934	14	-	26472758	Jiyoye	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	1.583673036871672	[72]	[164]	8	hSpCas9	negative selection	142408
50644834	50644857	14	-	26472758	Jiyoye	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.349459883649586	[101]	[97]	2	hSpCas9	negative selection	142409
50644734	50644757	14	+	26472758	Jiyoye	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	-0.7481028439720374	[97]	[43]	-5	hSpCas9	negative selection	142410
50640805	50640828	14	+	26472758	Jiyoye	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	-1.34005854811416	[140]	[41]	-7	hSpCas9	negative selection	142411
50644928	50644951	14	+	26472758	Jiyoye	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	2.379161005336277	[12]	[50]	9	hSpCas9	negative selection	142412
50667864	50667887	14	+	26472758	KBM7	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	-0.027772962088251307	[686,774]	[399,287]	0	hSpCas9	negative selection	333521
50644939	50644962	14	-	26472758	KBM7	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.37593551598287434	[2028,1637]	[1008,1203]	4	hSpCas9	negative selection	333522
50644819	50644842	14	+	26472758	KBM7	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.4759685338111731	[638,581]	[478,327]	5	hSpCas9	negative selection	333523
50640867	50640890	14	+	26472758	KBM7	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.19643064152850132	[1197,772]	[694,366]	2	hSpCas9	negative selection	333524
50640852	50640875	14	+	26472758	KBM7	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.3495524823947084	[300,368]	[264,148]	4	hSpCas9	negative selection	333525
50644911	50644934	14	-	26472758	KBM7	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.41855393204867275	[404,438]	[180,344]	4	hSpCas9	negative selection	333526
50644834	50644857	14	-	26472758	KBM7	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.4304006705334656	[609,501]	[321,375]	4	hSpCas9	negative selection	333527
50644734	50644757	14	+	26472758	KBM7	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	0.784111907477768	[488,525]	[424,404]	8	hSpCas9	negative selection	333528
50640805	50640828	14	+	26472758	KBM7	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	1.3106858530315506	[339,343]	[446,359]	9	hSpCas9	negative selection	333529
50644928	50644951	14	+	26472758	KBM7	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	0.761507733565843	[184,168]	[119,159]	8	hSpCas9	negative selection	333530
50667864	50667887	14	+	26472758	Raji	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.34271501241754554	[332]	[97]	3	hSpCas9	negative selection	524639
50644939	50644962	14	-	26472758	Raji	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.3517393881826183	[1191]	[352]	3	hSpCas9	negative selection	524640
50644819	50644842	14	+	26472758	Raji	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.7698021761747516	[277]	[109]	7	hSpCas9	negative selection	524641
50640867	50640890	14	+	26472758	Raji	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.4833212149635029	[560]	[181]	4	hSpCas9	negative selection	524642
50640852	50640875	14	+	26472758	Raji	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.3074081436815927	[194]	[55]	3	hSpCas9	negative selection	524643
50644911	50644934	14	-	26472758	Raji	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.6406839162722631	[198]	[71]	6	hSpCas9	negative selection	524644
50644834	50644857	14	-	26472758	Raji	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.14475038783808436	[342]	[87]	1	hSpCas9	negative selection	524645
50644734	50644757	14	+	26472758	Raji	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	0.2269651511262721	[242]	[65]	2	hSpCas9	negative selection	524646
50640805	50640828	14	+	26472758	Raji	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	0.495199565917419	[213]	[69]	5	hSpCas9	negative selection	524647
50644928	50644951	14	+	26472758	Raji	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	1.050050360307648	[76]	[36]	8	hSpCas9	negative selection	524648
50667864	50667887	14	+	26472758	K562	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.2350687594838632	[773]	[768]	1	hSpCas9	negative selection	715757
50644939	50644962	14	-	26472758	K562	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.8068805154428011	[1356]	[2003]	6	hSpCas9	negative selection	715758
50644819	50644842	14	+	26472758	K562	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.28174426335526703	[495]	[508]	2	hSpCas9	negative selection	715759
50640867	50640890	14	+	26472758	K562	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.4527069945929443	[836]	[966]	3	hSpCas9	negative selection	715760
50640852	50640875	14	+	26472758	K562	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	1.3957568314519293	[216]	[481]	9	hSpCas9	negative selection	715761
50644911	50644934	14	-	26472758	K562	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.1979442978669463	[346]	[335]	1	hSpCas9	negative selection	715762
50644834	50644857	14	-	26472758	K562	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.22133511455340557	[377]	[371]	1	hSpCas9	negative selection	715763
50644734	50644757	14	+	26472758	K562	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	1.7331659131283	[309]	[869]	9	hSpCas9	negative selection	715764
50640805	50640828	14	+	26472758	K562	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	0.8220092397312506	[326]	[487]	6	hSpCas9	negative selection	715765
50644928	50644951	14	+	26472758	K562	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	-0.49551843303105003	[161]	[96]	-3	hSpCas9	negative selection	715766
50635338	50635361	14	-	26627737	DLD1	viability	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.639578544293872	[275]	[199,122,86]	6	hSpCas9	negative selection	788673
50640852	50640875	14	+	26627737	DLD1	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.7244992119868245	[330]	[151,290,87]	7	hSpCas9	negative selection	788674
50644819	50644842	14	+	26627737	DLD1	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	1.0384801591604087	[356]	[137,266,276]	8	hSpCas9	negative selection	788675
50644840	50644863	14	+	26627737	DLD1	viability	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	1.267526647649126	[387]	[370,195,302]	9	hSpCas9	negative selection	788676
50644911	50644934	14	-	26627737	DLD1	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.09515615416111889	[565]	[69,94,306]	-1	hSpCas9	negative selection	788677
50635338	50635361	14	-	26627737	GBM cells	viability after 5 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	-0.12965527731108545	[203]	[110,88]	-2	hSpCas9	negative selection	870988
50640852	50640875	14	+	26627737	GBM cells	viability after 5 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.22520716233444982	[263]	[182,147]	3	hSpCas9	negative selection	870989
50644819	50644842	14	+	26627737	GBM cells	viability after 5 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-0.6738223235022112	[234]	[72,84]	-8	hSpCas9	negative selection	870990
50644840	50644863	14	+	26627737	GBM cells	viability after 5 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.3542410951902464	[255]	[158,191]	5	hSpCas9	negative selection	870991
50644911	50644934	14	-	26627737	GBM cells	viability after 5 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.8921392348428181	[307]	[94,82]	-8	hSpCas9	negative selection	870992
50635338	50635361	14	-	26627737	GBM cells	viability after 13 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	-0.09499156091003474	[203]	[128,82]	-1	hSpCas9	negative selection	953303
50640852	50640875	14	+	26627737	GBM cells	viability after 13 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	-0.4544243906765883	[263]	[146,69]	-5	hSpCas9	negative selection	953304
50644819	50644842	14	+	26627737	GBM cells	viability after 13 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-1.177242042568741	[234]	[62,50]	-8	hSpCas9	negative selection	953305
50644840	50644863	14	+	26627737	GBM cells	viability after 13 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.25362355070824094	[255]	[185,148]	3	hSpCas9	negative selection	953306
50644911	50644934	14	-	26627737	GBM cells	viability after 13 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.44449938977980374	[307]	[140,107]	-5	hSpCas9	negative selection	953307
50635338	50635361	14	-	26627737	GBM cells	viability after 21 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	-0.48294308153922105	[203]	[83,74]	-4	hSpCas9	negative selection	1035618
50640852	50640875	14	+	26627737	GBM cells	viability after 21 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	-0.38309258920546657	[263]	[133,87]	-3	hSpCas9	negative selection	1035619
50644819	50644842	14	+	26627737	GBM cells	viability after 21 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-1.1656452056815478	[234]	[58,54]	-7	hSpCas9	negative selection	1035620
50644840	50644863	14	+	26627737	GBM cells	viability after 21 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.8618957115863538	[255]	[269,236]	8	hSpCas9	negative selection	1035621
50644911	50644934	14	-	26627737	GBM cells	viability after 21 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-1.4579197245831423	[307]	[62,58]	-8	hSpCas9	negative selection	1035622
50635338	50635361	14	-	26627737	RPE1	viability after 9 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	2.1275820473142923	[248]	[227,485]	9	hSpCas9	negative selection	1117933
50640852	50640875	14	+	26627737	RPE1	viability after 9 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	2.179321907431523	[264]	[294,479]	9	hSpCas9	negative selection	1117934
50644819	50644842	14	+	26627737	RPE1	viability after 9 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.36626881274148304	[1327]	[462,629]	2	hSpCas9	negative selection	1117935
50644840	50644863	14	+	26627737	RPE1	viability after 9 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.7386231123013884	[403]	[231,183]	5	hSpCas9	negative selection	1117936
50644911	50644934	14	-	26627737	RPE1	viability after 9 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.754288888474424	[1345]	[282,206]	-5	hSpCas9	negative selection	1117937
50635338	50635361	14	-	26627737	RPE1	viability after 12 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	2.1780585910297123	[248]	[344,257]	9	hSpCas9	negative selection	1200248
50640852	50640875	14	+	26627737	RPE1	viability after 12 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	1.8542912359785106	[264]	[254,259]	8	hSpCas9	negative selection	1200249
50644819	50644842	14	+	26627737	RPE1	viability after 12 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.5367657874313583	[1327]	[452,585]	3	hSpCas9	negative selection	1200250
50644840	50644863	14	+	26627737	RPE1	viability after 12 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	1.027480149250971	[403]	[297,139]	6	hSpCas9	negative selection	1200251
50644911	50644934	14	-	26627737	RPE1	viability after 12 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.7166168920851602	[1345]	[238,199]	-5	hSpCas9	negative selection	1200252
50635338	50635361	14	-	26627737	RPE1	viability after 15 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	2.455927972554348	[248]	[247,519]	9	hSpCas9	negative selection	1282563
50640852	50640875	14	+	26627737	RPE1	viability after 15 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	2.287680423159591	[264]	[392,339]	9	hSpCas9	negative selection	1282564
50644819	50644842	14	+	26627737	RPE1	viability after 15 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.6896302540349077	[1327]	[639,572]	4	hSpCas9	negative selection	1282565
50644840	50644863	14	+	26627737	RPE1	viability after 15 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	1.306753209966623	[403]	[382,185]	7	hSpCas9	negative selection	1282566
50644911	50644934	14	-	26627737	RPE1	viability after 15 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.497192321340936	[1345]	[198,337]	-3	hSpCas9	negative selection	1282567
50635338	50635361	14	-	26627737	RPE1	viability after 18 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	2.647294027588027	[248]	[405,436]	9	hSpCas9	negative selection	1364878
50640852	50640875	14	+	26627737	RPE1	viability after 18 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	1.725270320788654	[264]	[278,190]	8	hSpCas9	negative selection	1364879
50644819	50644842	14	+	26627737	RPE1	viability after 18 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.8910474408885085	[1327]	[653,675]	5	hSpCas9	negative selection	1364880
50644840	50644863	14	+	26627737	RPE1	viability after 18 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	1.6611163671032685	[403]	[484,194]	8	hSpCas9	negative selection	1364881
50644911	50644934	14	-	26627737	RPE1	viability after 18 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.31525089274713375	[1345]	[333,246]	-2	hSpCas9	negative selection	1364882
50635338	50635361	14	-	26627737	HeLa	viability after 8 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	-0.118996929821235	[169]	[117,53,44]	-1	hSpCas9	negative selection	1447193
50640852	50640875	14	+	26627737	HeLa	viability after 8 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.6550122266347816	[273]	[200,130,230]	5	hSpCas9	negative selection	1447194
50644819	50644842	14	+	26627737	HeLa	viability after 8 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.23440636119741398	[255]	[231,46,135]	2	hSpCas9	negative selection	1447195
50644840	50644863	14	+	26627737	HeLa	viability after 8 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.35329129888981153	[394]	[228,333,105]	3	hSpCas9	negative selection	1447196
50644911	50644934	14	-	26627737	HeLa	viability after 8 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	1.0828297820608954	[283]	[331,195,271]	8	hSpCas9	negative selection	1447197
50635338	50635361	14	-	26627737	HeLa	viability after 12 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.5858321671897461	[169]	[139,136,36]	5	hSpCas9	negative selection	1529508
50640852	50640875	14	+	26627737	HeLa	viability after 12 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.6522463479593492	[273]	[354,64,130]	5	hSpCas9	negative selection	1529509
50644819	50644842	14	+	26627737	HeLa	viability after 12 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-0.332209263843406	[255]	[30,145,66]	-3	hSpCas9	negative selection	1529510
50644840	50644863	14	+	26627737	HeLa	viability after 12 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.23344083515561978	[394]	[241,221,109]	2	hSpCas9	negative selection	1529511
50644911	50644934	14	-	26627737	HeLa	viability after 12 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.41179421202768385	[283]	[249,81,146]	3	hSpCas9	negative selection	1529512
50635338	50635361	14	-	26627737	HeLa	viability after 15 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.5459452089740024	[169]	[57,176,65]	4	hSpCas9	negative selection	1611823
50640852	50640875	14	+	26627737	HeLa	viability after 15 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	1.1457502305517357	[273]	[419,121,191]	7	hSpCas9	negative selection	1611824
50644819	50644842	14	+	26627737	HeLa	viability after 15 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-0.19158627532372008	[255]	[115,119,32]	-2	hSpCas9	negative selection	1611825
50644840	50644863	14	+	26627737	HeLa	viability after 15 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	-0.021222896350987636	[394]	[185,166,118]	0	hSpCas9	negative selection	1611826
50644911	50644934	14	-	26627737	HeLa	viability after 15 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.5814648749370817	[283]	[167,166,184]	5	hSpCas9	negative selection	1611827
50635338	50635361	14	-	26627737	HeLa	viability after 18 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.5637126931776119	[169]	[40,146,65]	4	hSpCas9	negative selection	1694138
50640852	50640875	14	+	26627737	HeLa	viability after 18 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	1.1777818564274343	[273]	[290,102,191]	8	hSpCas9	negative selection	1694139
50644819	50644842	14	+	26627737	HeLa	viability after 18 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-0.14144979026240956	[255]	[81,101,32]	-1	hSpCas9	negative selection	1694140
50644840	50644863	14	+	26627737	HeLa	viability after 18 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	-0.1031926971590035	[394]	[115,127,118]	-1	hSpCas9	negative selection	1694141
50644911	50644934	14	-	26627737	HeLa	viability after 18 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.6280890921573576	[283]	[119,142,184]	5	hSpCas9	negative selection	1694142
50635338	50635361	14	-	26627737	HCT116	viability after 6 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.627312955364046	[385]	[85,97]	3	hSpCas9	negative selection	1776453
50640852	50640875	14	+	26627737	HCT116	viability after 6 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.25106907017059676	[606]	[197,66]	1	hSpCas9	negative selection	1776454
50644819	50644842	14	+	26627737	HCT116	viability after 6 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.02783002835733743	[665]	[205,51]	0	hSpCas9	negative selection	1776455
50644840	50644863	14	+	26627737	HCT116	viability after 6 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.1615981845823495	[605]	[83,118]	0	hSpCas9	negative selection	1776456
50644911	50644934	14	-	26627737	HCT116	viability after 6 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.5337847998483082	[1226]	[752,17]	3	hSpCas9	negative selection	1776457
50635338	50635361	14	-	26627737	HCT116	viability after 8 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.8987952669330822	[104]	[125,93,103]	7	hSpCas9	negative selection	1858768
50640852	50640875	14	+	26627737	HCT116	viability after 8 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	-0.20421421375341087	[324]	[131,184,148]	-2	hSpCas9	negative selection	1858769
50644819	50644842	14	+	26627737	HCT116	viability after 8 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.1271682798349565	[136]	[60,106,78]	1	hSpCas9	negative selection	1858770
50644840	50644863	14	+	26627737	HCT116	viability after 8 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.189997655225553	[234]	[143,143,154]	2	hSpCas9	negative selection	1858771
50644911	50644934	14	-	26627737	HCT116	viability after 8 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.10438788180660419	[405]	[155,310,156]	-1	hSpCas9	negative selection	1858772
50635338	50635361	14	-	26627737	HCT116	viability after 9 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.7949682946529646	[385]	[127,218]	5	hSpCas9	negative selection	1941083
50640852	50640875	14	+	26627737	HCT116	viability after 9 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.328481751936922	[606]	[250,165]	2	hSpCas9	negative selection	1941084
50644819	50644842	14	+	26627737	HCT116	viability after 9 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-0.7749489728270772	[665]	[75,125]	-5	hSpCas9	negative selection	1941085
50644840	50644863	14	+	26627737	HCT116	viability after 9 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	-1.3242391230368042	[605]	[134,8]	-7	hSpCas9	negative selection	1941086
50644911	50644934	14	-	26627737	HCT116	viability after 9 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-1.8883976049010225	[1226]	[78,95]	-8	hSpCas9	negative selection	1941087
50635338	50635361	14	-	26627737	HCT116	viability after 12 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.5592702619899222	[104]	[93,88,59]	5	hSpCas9	negative selection	2023398
50640852	50640875	14	+	26627737	HCT116	viability after 12 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	-0.06993024898511671	[324]	[196,115,170]	0	hSpCas9	negative selection	2023399
50644819	50644842	14	+	26627737	HCT116	viability after 12 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.09428902062914934	[136]	[62,43,123]	1	hSpCas9	negative selection	2023400
50644840	50644863	14	+	26627737	HCT116	viability after 12 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.9758272358995506	[234]	[230,212,284]	8	hSpCas9	negative selection	2023401
50644911	50644934	14	-	26627737	HCT116	viability after 12 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.10796435966620543	[405]	[317,225,137]	1	hSpCas9	negative selection	2023402
50635338	50635361	14	-	26627737	HCT116	viability after 15 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	1.0992293317456232	[104]	[117,121,145]	8	hSpCas9	negative selection	2105713
50640852	50640875	14	+	26627737	HCT116	viability after 15 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	-0.3809573403630482	[324]	[205,36,193]	-4	hSpCas9	negative selection	2105714
50644819	50644842	14	+	26627737	HCT116	viability after 15 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.6826186842733121	[136]	[126,47,202]	6	hSpCas9	negative selection	2105715
50644840	50644863	14	+	26627737	HCT116	viability after 15 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.9120966154648718	[234]	[221,115,417]	7	hSpCas9	negative selection	2105716
50644911	50644934	14	-	26627737	HCT116	viability after 15 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.17442824109005728	[405]	[480,162,172]	1	hSpCas9	negative selection	2105717
50635338	50635361	14	-	26627737	HCT116	viability after 18 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	1.834986706081577	[104]	[149,324,52]	9	hSpCas9	negative selection	2188028
50640852	50640875	14	+	26627737	HCT116	viability after 18 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	-0.32828954046925396	[324]	[157,63,158]	-3	hSpCas9	negative selection	2188029
50644819	50644842	14	+	26627737	HCT116	viability after 18 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.5915565289458199	[136]	[82,75,143]	5	hSpCas9	negative selection	2188030
50644840	50644863	14	+	26627737	HCT116	viability after 18 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	1.0513018437481456	[234]	[159,217,333]	7	hSpCas9	negative selection	2188031
50644911	50644934	14	-	26627737	HCT116	viability after 18 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.3664673777010752	[405]	[399,210,145]	3	hSpCas9	negative selection	2188032
50644928	50644951	14	-	24336569	HL60	viability	CCTTCCTCCTGGCTGGTCTGTGG	SAV1	ENSG00000151748	0.26186203117084145	[347]	[882]	2	hSpCas9	negative selection	2293910
50644966	50644989	14	-	24336569	HL60	viability	TTAGGAAATTTGACTAACCATGG	SAV1	ENSG00000151748	1.274472886423365	[217]	[1115]	8	hSpCas9	negative selection	2293911
50644984	50645007	14	-	24336569	HL60	viability	AGAGTTGCTGCTACATCTTTAGG	SAV1	ENSG00000151748	0.5815009120935332	[191]	[607]	5	hSpCas9	negative selection	2293912
50665448	50665471	14	+	24336569	HL60	viability	TCTCTTCTCATTATTTCATGAGG	SAV1	ENSG00000151748	-1.0052580228971024	[718]	[757]	-7	hSpCas9	negative selection	2293913
50665559	50665582	14	+	24336569	HL60	viability	AGACAGATATCAGTTCGTCTTGG	SAV1	ENSG00000151748	-1.014175970833095	[376]	[394]	-7	hSpCas9	negative selection	2293914
50665568	50665591	14	+	24336569	HL60	viability	TCAGTTCGTCTTGGAATTGTTGG	SAV1	ENSG00000151748	0.7740819655816218	[592]	[2145]	6	hSpCas9	negative selection	2293915
50665578	50665601	14	+	24336569	HL60	viability	TTGGAATTGTTGGACCATGCCGG	SAV1	ENSG00000151748	-0.28048201359153535	[550]	[959]	-2	hSpCas9	negative selection	2293916
50665592	50665615	14	-	24336569	HL60	viability	ATGCCTTCATTCATCCGGCATGG	SAV1	ENSG00000151748	-0.7776164603668902	[818]	[1010]	-6	hSpCas9	negative selection	2293917
50665597	50665620	14	-	24336569	HL60	viability	ATCTTATGCCTTCATTCATCCGG	SAV1	ENSG00000151748	0.059935766100466886	[436]	[963]	0	hSpCas9	negative selection	2293918
50667864	50667887	14	+	24336569	HL60	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.206112489467689	[781]	[1908]	2	hSpCas9	negative selection	2293919
50644928	50644951	14	-	24336569	KBM7	viability	CCTTCCTCCTGGCTGGTCTGTGG	SAV1	ENSG00000151748	0.6704616733286647	[345]	[1501]	6	hSpCas9	negative selection	2361087
50644966	50644989	14	-	24336569	KBM7	viability	TTAGGAAATTTGACTAACCATGG	SAV1	ENSG00000151748	0.4500590858214397	[218]	[815]	4	hSpCas9	negative selection	2361088
50644984	50645007	14	-	24336569	KBM7	viability	AGAGTTGCTGCTACATCTTTAGG	SAV1	ENSG00000151748	0.5617414314275957	[269]	[1086]	5	hSpCas9	negative selection	2361089
50665448	50665471	14	+	24336569	KBM7	viability	TCTCTTCTCATTATTTCATGAGG	SAV1	ENSG00000151748	2.2996547330711508	[153]	[2067]	9	hSpCas9	negative selection	2361090
50665559	50665582	14	+	24336569	KBM7	viability	AGACAGATATCAGTTCGTCTTGG	SAV1	ENSG00000151748	0.13738330417227362	[228]	[686]	1	hSpCas9	negative selection	2361091
50665568	50665591	14	+	24336569	KBM7	viability	TCAGTTCGTCTTGGAATTGTTGG	SAV1	ENSG00000151748	-0.22591138348527107	[568]	[1326]	-2	hSpCas9	negative selection	2361092
50665578	50665601	14	+	24336569	KBM7	viability	TTGGAATTGTTGGACCATGCCGG	SAV1	ENSG00000151748	-0.4485126776819931	[772]	[1544]	-4	hSpCas9	negative selection	2361093
50665592	50665615	14	-	24336569	KBM7	viability	ATGCCTTCATTCATCCGGCATGG	SAV1	ENSG00000151748	0.8676895622242691	[303]	[1512]	7	hSpCas9	negative selection	2361094
50665597	50665620	14	-	24336569	KBM7	viability	ATCTTATGCCTTCATTCATCCGG	SAV1	ENSG00000151748	0.7857549750694913	[318]	[1499]	7	hSpCas9	negative selection	2361095
50667864	50667887	14	+	24336569	KBM7	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	-1.1149350872905903	[616]	[776]	-7	hSpCas9	negative selection	2361096
50667919	50667942	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGAAGTGTCCAAGCCGGCCGAGG	SAV1	ENSG00000151748	0.3873634060490994	[3,2]	[2,4]	7	hSpCas9	positive selection	3018735
50665254	50665277	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCATGTGCACGATCTCCAAGTGG	SAV1	ENSG00000151748	0.7726139185134224	[3,3]	[3,7]	9	hSpCas9	positive selection	3018736
50665449	50665472	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTCTTCTCATTATTTCATGAGG	SAV1	ENSG00000151748	0.4540036483535675	[3,3]	[3,5]	8	hSpCas9	positive selection	3018737
50667865	50667888	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.8011377780004184	[3,3]	[4,6]	9	hSpCas9	positive selection	3018738
50667919	50667942	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGAAGTGTCCAAGCCGGCCGAGG	SAV1	ENSG00000151748	-0.5998693773051503	[3,3]	[2,0]	-8	hSpCas9	positive selection	3086593
50665254	50665277	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCATGTGCACGATCTCCAAGTGG	SAV1	ENSG00000151748	0.21138335704687705	[3,3]	[3,2]	4	hSpCas9	positive selection	3086594
50665449	50665472	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTCTTCTCATTATTTCATGAGG	SAV1	ENSG00000151748	0.11056982410272254	[3,3]	[3,1]	2	hSpCas9	positive selection	3086595
50667865	50667888	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.38524766353600914	[3,3]	[3,3]	6	hSpCas9	positive selection	3086596
50665559	50665582		+	24336571	A375	resistance to PLX after 7 days	AGACAGATATCAGTTCGTCTTGG	SAV1	ENSG00000151748	-0.2820486818647515	[21,14]	[13,15]	-8	hSpCas9	positive selection	3142644
50640779	50640802		-	24336571	A375	resistance to PLX after 7 days	ATACTGCAGAAATTCCTGACTGG	SAV1	ENSG00000151748	0.18693583675094538	[21,25]	[26,27]	6	hSpCas9	positive selection	3142645
50640795	50640818		+	24336571	A375	resistance to PLX after 7 days	GCAGTATGATATGGATTTGCAGG	SAV1	ENSG00000151748	-0.26313113504927316	[9,10]	[7,8]	-7	hSpCas9	positive selection	3142646
50640765	50640788		+	24336571	A375	resistance to PLX after 7 days	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.0845247903923928	[8,10]	[8,10]	3	hSpCas9	positive selection	3142647
50665589	50665612		+	24336571	A375	resistance to PLX after 7 days	GGACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.12343473405353106	[8,6]	[7,9]	4	hSpCas9	positive selection	3142648
50665559	50665582		+	24336571	A375	resistance to PLX after 14 days	AGACAGATATCAGTTCGTCTTGG	SAV1	ENSG00000151748	-0.5855790058082077	[30,19]	[7,6]	-7	hSpCas9	positive selection	3200437
50640779	50640802		-	24336571	A375	resistance to PLX after 14 days	ATACTGCAGAAATTCCTGACTGG	SAV1	ENSG00000151748	1.0486420124442242	[23,32]	[24,29]	8	hSpCas9	positive selection	3200438
50640795	50640818		+	24336571	A375	resistance to PLX after 14 days	GCAGTATGATATGGATTTGCAGG	SAV1	ENSG00000151748	0.2524815674912879	[3,7]	[2,3]	2	hSpCas9	positive selection	3200439
50640765	50640788		+	24336571	A375	resistance to PLX after 14 days	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.5339478311536501	[9,12]	[5,8]	5	hSpCas9	positive selection	3200440
50665589	50665612		+	24336571	A375	resistance to PLX after 14 days	GGACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	1.3513995259927136	[10,5]	[8,10]	8	hSpCas9	positive selection	3200441
50665559	50665582		+	24336571	A375	viability after 7 days	AGACAGATATCAGTTCGTCTTGG	SAV1	ENSG00000151748	0.24342677887153402	[15]	[21,14]	3	hSpCas9	negative selection	3258230
50640779	50640802		-	24336571	A375	viability after 7 days	ATACTGCAGAAATTCCTGACTGG	SAV1	ENSG00000151748	0.22015185576584506	[21]	[21,25]	3	hSpCas9	negative selection	3258231
50640795	50640818		+	24336571	A375	viability after 7 days	GCAGTATGATATGGATTTGCAGG	SAV1	ENSG00000151748	-0.015953762916198655	[10]	[9,10]	0	hSpCas9	negative selection	3258232
50640765	50640788		+	24336571	A375	viability after 7 days	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.6006041281486956	[6]	[8,10]	8	hSpCas9	negative selection	3258233
50665589	50665612		+	24336571	A375	viability after 7 days	GGACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.5354199407024565	[5]	[8,6]	7	hSpCas9	negative selection	3258234
50665559	50665582		+	24336571	A375	viability after 14 days	AGACAGATATCAGTTCGTCTTGG	SAV1	ENSG00000151748	0.7030566141118744	[15]	[30,19]	8	hSpCas9	negative selection	3316023
50640779	50640802		-	24336571	A375	viability after 14 days	ATACTGCAGAAATTCCTGACTGG	SAV1	ENSG00000151748	0.45930900932067364	[21]	[23,32]	6	hSpCas9	negative selection	3316024
50640795	50640818		+	24336571	A375	viability after 14 days	GCAGTATGATATGGATTTGCAGG	SAV1	ENSG00000151748	-0.7820585069233064	[10]	[3,7]	-7	hSpCas9	negative selection	3316025
50640765	50640788		+	24336571	A375	viability after 14 days	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.8558985276265823	[6]	[9,12]	9	hSpCas9	negative selection	3316026
50665589	50665612		+	24336571	A375	viability after 14 days	GGACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.5769690668863984	[5]	[10,5]	7	hSpCas9	negative selection	3316027
50635308	50635331	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-1.5975421718144014	[462,462]	[0,0]	-9	hSpCas9	positive selection	3391240
50640765	50640788	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.5158592250446882	[106,106]	[0,0]	2	hSpCas9	positive selection	3391241
50635239	50635262	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.7815927804794374	[88,88]	[0,0]	4	hSpCas9	positive selection	3391242
50667919	50667942	14	-	26780180	HT29	viability (Avana library 4 designs)	CGAAGTGTCCAAGCCGGCCGAGG	SAV1	ENSG00000151748	0.0231642343293592	[]	[]	0	hSpCas9	negative selection	3457144
50665253	50665276	14	+	26780180	HT29	viability (Avana library 4 designs)	TCATGTGCACGATCTCCAAGTGG	SAV1	ENSG00000151748	1.39092181247899	[]	[]	5	hSpCas9	negative selection	3457145
50665448	50665471	14	+	26780180	HT29	viability (Avana library 4 designs)	TCTCTTCTCATTATTTCATGAGG	SAV1	ENSG00000151748	0.155887435800307	[]	[]	0	hSpCas9	negative selection	3457146
50667864	50667887	14	+	26780180	HT29	viability (Avana library 4 designs)	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	-0.48228094955736	[]	[]	-7	hSpCas9	negative selection	3457147
50665253	50665276	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCATGTGCACGATCTCCAAGTGG	SAV1	ENSG00000151748	1.46387803922603	[]	[]	2	hSpCas9	negative selection	3555964
50667919	50667942	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAAGTGTCCAAGCCGGCCGAGG	SAV1	ENSG00000151748	9.26685747386343	[]	[]	9	hSpCas9	negative selection	3555965
50667864	50667887	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	3.54731571705853	[]	[]	5	hSpCas9	negative selection	3555966
50665448	50665471	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCTTCTCATTATTTCATGAGG	SAV1	ENSG00000151748	-12.4197237055138	[]	[]	-8	hSpCas9	negative selection	3555967
50667902	50667925	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	CACGTACTTCCCCTGCACCTCGG	SAV1	ENSG00000151748	5.37276612849395	[]	[]	8	hSpCas9	negative selection	3555968
50665382	50665405	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGATGTCCCTAGAGAGTATGG	SAV1	ENSG00000151748	6.08707176145991	[]	[]	9	hSpCas9	negative selection	3555969
50665253	50665276	14	+	26780180	A375	viability (Avana lentiGuide)	TCATGTGCACGATCTCCAAGTGG	SAV1	ENSG00000151748	-8.07613241721656	[]	[]	-9	hSpCas9	negative selection	3664623
50667919	50667942	14	-	26780180	A375	viability (Avana lentiGuide)	CGAAGTGTCCAAGCCGGCCGAGG	SAV1	ENSG00000151748	-5.79316676891481	[]	[]	-8	hSpCas9	negative selection	3664624
50667864	50667887	14	+	26780180	A375	viability (Avana lentiGuide)	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	-11.8190258050199	[]	[]	-9	hSpCas9	negative selection	3664625
50665448	50665471	14	+	26780180	A375	viability (Avana lentiGuide)	TCTCTTCTCATTATTTCATGAGG	SAV1	ENSG00000151748	-9.9156981948504	[]	[]	-9	hSpCas9	negative selection	3664626
50667902	50667925	14	+	26780180	A375	viability (Avana lentiGuide)	CACGTACTTCCCCTGCACCTCGG	SAV1	ENSG00000151748	-9.96075637029379	[]	[]	-9	hSpCas9	negative selection	3664627
50665382	50665405	14	-	26780180	A375	viability (Avana lentiGuide)	GCAGATGTCCCTAGAGAGTATGG	SAV1	ENSG00000151748	-11.004761807116	[]	[]	-9	hSpCas9	negative selection	3664628
50665253	50665276	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATGTGCACGATCTCCAAGTGG	SAV1	ENSG00000151748	-0.05991867033223275	[5]	[5,4]	-1	hSpCas9	positive selection	3773230
50667919	50667942	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAAGTGTCCAAGCCGGCCGAGG	SAV1	ENSG00000151748	0.19483168843840665	[4]	[6,3]	5	hSpCas9	positive selection	3773231
50667864	50667887	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.19192162749964337	[4]	[5,4]	5	hSpCas9	positive selection	3773232
50665448	50665471	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCTTCTCATTATTTCATGAGG	SAV1	ENSG00000151748	-1.0491184377626177	[5]	[1,2]	-9	hSpCas9	positive selection	3773233
50667902	50667925	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACGTACTTCCCCTGCACCTCGG	SAV1	ENSG00000151748	0.5058354341485038	[4]	[7,6]	9	hSpCas9	positive selection	3773234
50665382	50665405	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGATGTCCCTAGAGAGTATGG	SAV1	ENSG00000151748	0.3575060780217134	[6]	[7,7]	9	hSpCas9	positive selection	3773235
50665253	50665276	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATGTGCACGATCTCCAAGTGG	SAV1	ENSG00000151748	0.25188895110560006	[5]	[5,5]	6	hSpCas9	positive selection	3881837
50667919	50667942	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAAGTGTCCAAGCCGGCCGAGG	SAV1	ENSG00000151748	-0.15766721507528955	[4]	[2,4]	-2	hSpCas9	positive selection	3881838
50667864	50667887	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.6222014566817121	[5]	[6,7]	9	hSpCas9	positive selection	3881839
50665448	50665471	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCTTCTCATTATTTCATGAGG	SAV1	ENSG00000151748	0.8204188939046869	[4]	[6,8]	9	hSpCas9	positive selection	3881840
50667902	50667925	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACGTACTTCCCCTGCACCTCGG	SAV1	ENSG00000151748	0.4062531713907365	[6]	[7,6]	9	hSpCas9	positive selection	3881841
50665382	50665405	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGATGTCCCTAGAGAGTATGG	SAV1	ENSG00000151748	0.5468348118244478	[7]	[9,8]	9	hSpCas9	positive selection	3881842
50635239	50635262	14	-	26780180	A375	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.910080484994745	[]	[]	4	hSpCas9	negative selection	3991854
50635308	50635331	14	+	26780180	A375	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.274877103853042	[]	[]	-7	hSpCas9	negative selection	3991855
50644846	50644869	14	-	26780180	A375	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	0.752973086583044	[]	[]	3	hSpCas9	negative selection	3991856
50644804	50644827	14	-	26780180	A375	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.759845133182607	[]	[]	3	hSpCas9	negative selection	3991857
50640765	50640788	14	+	26780180	A375	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.909047058255955	[]	[]	4	hSpCas9	negative selection	3991858
50640867	50640890	14	+	26780180	A375	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.752178282970906	[]	[]	2	hSpCas9	negative selection	3991859
50635239	50635262	14	-	26780180	HT29	viability (GeCKOv2 library)	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.923542517017409	[]	[]	4	hSpCas9	negative selection	4099820
50635308	50635331	14	+	26780180	HT29	viability (GeCKOv2 library)	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.0940263177781063	[]	[]	0	hSpCas9	negative selection	4099821
50644846	50644869	14	-	26780180	HT29	viability (GeCKOv2 library)	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	1.09376416022913	[]	[]	5	hSpCas9	negative selection	4099822
50644804	50644827	14	-	26780180	HT29	viability (GeCKOv2 library)	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.589274272676356	[]	[]	2	hSpCas9	negative selection	4099823
50640765	50640788	14	+	26780180	HT29	viability (GeCKOv2 library)	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	1.11907683319554	[]	[]	5	hSpCas9	negative selection	4099824
50640867	50640890	14	+	26780180	HT29	viability (GeCKOv2 library)	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	1.44270673859718	[]	[]	7	hSpCas9	negative selection	4099825
50665559	50665582	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACAGATATCAGTTCGTCTTGG	SAV1	ENSG00000151748	-0.034737279837250876	[3]	[1,2]	-1	hSpCas9	positive selection	4168401
50640779	50640802	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATACTGCAGAAATTCCTGACTGG	SAV1	ENSG00000151748	0.5689918255099047	[4]	[3,4]	9	hSpCas9	positive selection	4168402
50640795	50640818	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGTATGATATGGATTTGCAGG	SAV1	ENSG00000151748	-0.39523193840665904	[3]	[1,1]	-7	hSpCas9	positive selection	4168403
50640765	50640788	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.32824906537553994	[2]	[1,2]	7	hSpCas9	positive selection	4168404
50665589	50665612	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	1.1059068669832013	[2]	[4,3]	9	hSpCas9	positive selection	4168405
50665559	50665582	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACAGATATCAGTTCGTCTTGG	SAV1	ENSG00000151748	-0.06788867537787348	[3]	[4,0,0,0]	-1	hSpCas9	positive selection	4232423
50640779	50640802	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATACTGCAGAAATTCCTGACTGG	SAV1	ENSG00000151748	0.46298859456632424	[4]	[4,4,3,0]	3	hSpCas9	positive selection	4232424
50640795	50640818	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGTATGATATGGATTTGCAGG	SAV1	ENSG00000151748	0.20204216216702015	[3]	[2,3,0,0]	1	hSpCas9	positive selection	4232425
50640765	50640788	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	2.1445741311647146	[0]	[3,4,0,0]	9	hSpCas9	positive selection	4232426
50665589	50665612	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.28864189835991744	[2]	[2,0,2,0]	2	hSpCas9	positive selection	4232427
50644804	50644827	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.18500812767051394	[3]	[4,2]	4	hSpCas9	positive selection	4296415
50640867	50640890	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.5572848981645282	[2]	[3,2]	9	hSpCas9	positive selection	4296416
50644846	50644869	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	0.08483033875203166	[2]	[2,0]	1	hSpCas9	positive selection	4296417
50635308	50635331	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.38437314666809835	[4]	[4,4]	7	hSpCas9	positive selection	4360669
50640765	50640788	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	-0.229169256881121	[2]	[2,0]	-5	hSpCas9	positive selection	4360670
50635239	50635262	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.14622795503820413	[2]	[2,1]	3	hSpCas9	positive selection	4360671
50644911	50644933	14	-	27760321	OCIAML3	viability	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-1.3559056083510455	[332,348]	[102,106]	-8	hSpCas9	negative selection	4436902
50645000	50645022	14	+	27760321	OCIAML3	viability	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	0.43140574660138487	[181,200]	[189,220]	5	hSpCas9	negative selection	4436903
50665194	50665216	14	-	27760321	OCIAML3	viability	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	0.3160191935308586	[342,242]	[276,288]	3	hSpCas9	negative selection	4436904
50665483	50665505	14	+	27760321	OCIAML3	viability	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	-0.7492506708961144	[169,183]	[68,100]	-6	hSpCas9	negative selection	4436905
50665590	50665612	14	+	27760321	OCIAML3	viability	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.4818710888172286	[528,447]	[489,585]	6	hSpCas9	negative selection	4436906
50644911	50644933	14	-	27760321	OCIAML2	viability	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.24111353187977227	[332,348]	[303,358]	3	hSpCas9	negative selection	4520365
50645000	50645022	14	+	27760321	OCIAML2	viability	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	0.39285922739547396	[181,200]	[156,267]	5	hSpCas9	negative selection	4520366
50665194	50665216	14	-	27760321	OCIAML2	viability	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	0.3587004452459831	[342,242]	[285,319]	5	hSpCas9	negative selection	4520367
50665483	50665505	14	+	27760321	OCIAML2	viability	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	0.23115397009061023	[169,183]	[144,200]	3	hSpCas9	negative selection	4520368
50665590	50665612	14	+	27760321	OCIAML2	viability	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.2611948527705415	[528,447]	[417,542]	3	hSpCas9	negative selection	4520369
50644911	50644933	14	-	27760321	MV411	viability	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.6939923264405358	[332,348]	[285,485]	5	hSpCas9	negative selection	4603828
50645000	50645022	14	+	27760321	MV411	viability	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	-2.5995506694108412	[181,200]	[24,14]	-9	hSpCas9	negative selection	4603829
50665194	50665216	14	-	27760321	MV411	viability	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	0.5564177873789192	[342,242]	[395,108]	4	hSpCas9	negative selection	4603830
50665483	50665505	14	+	27760321	MV411	viability	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	-2.600468009759159	[169,183]	[0,46]	-9	hSpCas9	negative selection	4603831
50665590	50665612	14	+	27760321	MV411	viability	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.773742865674982	[528,447]	[308,909]	6	hSpCas9	negative selection	4603832
50644911	50644933	14	-	27760321	HL60	viability	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.4158469686331626	[332,348]	[172,248]	-5	hSpCas9	negative selection	4687291
50645000	50645022	14	+	27760321	HL60	viability	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	-0.0006622651288730186	[181,200]	[190,121]	0	hSpCas9	negative selection	4687292
50665194	50665216	14	-	27760321	HL60	viability	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	0.1187007786184302	[342,242]	[176,341]	1	hSpCas9	negative selection	4687293
50665483	50665505	14	+	27760321	HL60	viability	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	0.12985744852934333	[169,183]	[133,185]	1	hSpCas9	negative selection	4687294
50665590	50665612	14	+	27760321	HL60	viability	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	-0.013877995224423956	[528,447]	[437,346]	0	hSpCas9	negative selection	4687295
50644911	50644933	14	-	27760321	HT1080	viability	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.8627235791713412	[348,272]	[305,136]	5	hSpCas9	negative selection	4770754
50645000	50645022	14	+	27760321	HT1080	viability	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	-1.2789765100376667	[200,156]	[26,31]	-5	hSpCas9	negative selection	4770755
50665194	50665216	14	-	27760321	HT1080	viability	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	1.8269825373016706	[242,189]	[232,385]	8	hSpCas9	negative selection	4770756
50665483	50665505	14	+	27760321	HT1080	viability	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	0.0939069983596117	[183,143]	[0,144]	0	hSpCas9	negative selection	4770757
50665590	50665612	14	+	27760321	HT1080	viability	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	2.3205976593874253	[447,349]	[942,630]	9	hSpCas9	negative selection	4770758
50644911	50644933	14	-	27760321	HT29	viability after 7 days	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.23866970467940313	[348,272]	[422,510,101]	-3	hSpCas9	negative selection	4854217
50645000	50645022	14	+	27760321	HT29	viability after 7 days	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	0.062259503208191846	[200,156]	[303,291,136]	0	hSpCas9	negative selection	4854218
50665194	50665216	14	-	27760321	HT29	viability after 7 days	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	0.188146455101044	[242,189]	[479,295,201]	3	hSpCas9	negative selection	4854219
50665483	50665505	14	+	27760321	HT29	viability after 7 days	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	0.07616363087154254	[183,143]	[320,177,182]	1	hSpCas9	negative selection	4854220
50665590	50665612	14	+	27760321	HT29	viability after 7 days	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.18022836263642047	[447,349]	[719,339,698]	2	hSpCas9	negative selection	4854221
50644911	50644933	14	-	27760321	HT29	viability after 25 days	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.5259012363737929	[348,272]	[437,462,652]	6	hSpCas9	negative selection	4937680
50645000	50645022	14	+	27760321	HT29	viability after 25 days	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	1.076806119943218	[200,156]	[601,345,323]	9	hSpCas9	negative selection	4937681
50665194	50665216	14	-	27760321	HT29	viability after 25 days	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	0.8434393197809825	[242,189]	[415,473,442]	8	hSpCas9	negative selection	4937682
50665483	50665505	14	+	27760321	HT29	viability after 25 days	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	0.35242996385996916	[183,143]	[269,194,251]	4	hSpCas9	negative selection	4937683
50665590	50665612	14	+	27760321	HT29	viability after 25 days	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.7091850390707387	[447,349]	[516,830,919]	7	hSpCas9	negative selection	4937684
50644911	50644933	14	-	27760321	HT29	viability after 22 days	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.423502769264715	[348,272]	[350,336,764]	4	hSpCas9	negative selection	5021143
50645000	50645022	14	+	27760321	HT29	viability after 22 days	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	0.8884159400499181	[200,156]	[508,339,295]	8	hSpCas9	negative selection	5021144
50665194	50665216	14	-	27760321	HT29	viability after 22 days	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	1.3653560447964765	[242,189]	[890,500,534]	9	hSpCas9	negative selection	5021145
50665483	50665505	14	+	27760321	HT29	viability after 22 days	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	-0.5056709297430417	[183,143]	[221,71,103]	-5	hSpCas9	negative selection	5021146
50665590	50665612	14	+	27760321	HT29	viability after 22 days	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.7322864631429721	[447,349]	[740,859,697]	8	hSpCas9	negative selection	5021147
50644911	50644933	14	-	27760321	HT29	viability after 19 days	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.6429105254510026	[348,272]	[346,628,663]	6	hSpCas9	negative selection	5104606
50645000	50645022	14	+	27760321	HT29	viability after 19 days	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	0.9304747106509303	[200,156]	[392,397,379]	8	hSpCas9	negative selection	5104607
50665194	50665216	14	-	27760321	HT29	viability after 19 days	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	0.9965715134380682	[242,189]	[482,455,539]	9	hSpCas9	negative selection	5104608
50665483	50665505	14	+	27760321	HT29	viability after 19 days	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	-0.39324534892401597	[183,143]	[164,129,135]	-4	hSpCas9	negative selection	5104609
50665590	50665612	14	+	27760321	HT29	viability after 19 days	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.534400473094136	[447,349]	[688,732,566]	5	hSpCas9	negative selection	5104610
50644911	50644933	14	-	27760321	HT29	viability after 16 days	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.06058328724205414	[348,272]	[431,229,350]	0	hSpCas9	negative selection	5188069
50645000	50645022	14	+	27760321	HT29	viability after 16 days	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	0.9780858820613862	[200,156]	[466,406,315]	9	hSpCas9	negative selection	5188070
50665194	50665216	14	-	27760321	HT29	viability after 16 days	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	0.8292690395066326	[242,189]	[383,499,400]	8	hSpCas9	negative selection	5188071
50665483	50665505	14	+	27760321	HT29	viability after 16 days	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	0.5604958038261172	[183,143]	[301,149,365]	6	hSpCas9	negative selection	5188072
50665590	50665612	14	+	27760321	HT29	viability after 16 days	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.10257248571721869	[447,349]	[591,461,394]	1	hSpCas9	negative selection	5188073
50644911	50644933	14	-	27760321	HT29	viability after 13 days	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.11131977433073592	[348,272]	[298,212,480]	-1	hSpCas9	negative selection	5271532
50645000	50645022	14	+	27760321	HT29	viability after 13 days	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	0.5428367760173398	[200,156]	[367,263,276]	7	hSpCas9	negative selection	5271533
50665194	50665216	14	-	27760321	HT29	viability after 13 days	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	0.7333931297564779	[242,189]	[448,288,508]	8	hSpCas9	negative selection	5271534
50665483	50665505	14	+	27760321	HT29	viability after 13 days	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	0.308095971994079	[183,143]	[374,122,209]	4	hSpCas9	negative selection	5271535
50665590	50665612	14	+	27760321	HT29	viability after 13 days	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.22999297004306105	[447,349]	[810,324,494]	3	hSpCas9	negative selection	5271536
50644911	50644933	14	-	27760321	HT29	viability after 10 days	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.11590464022489527	[348,272]	[252,323,493]	-1	hSpCas9	negative selection	5354995
50645000	50645022	14	+	27760321	HT29	viability after 10 days	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	0.8877703626311568	[200,156]	[592,501,153]	9	hSpCas9	negative selection	5354996
50665194	50665216	14	-	27760321	HT29	viability after 10 days	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	0.7492435387134019	[242,189]	[197,885,294]	8	hSpCas9	negative selection	5354997
50665483	50665505	14	+	27760321	HT29	viability after 10 days	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	-0.3659304704983699	[183,143]	[81,258,138]	-5	hSpCas9	negative selection	5354998
50665590	50665612	14	+	27760321	HT29	viability after 10 days	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.03911869688994499	[447,349]	[640,481,413]	0	hSpCas9	negative selection	5354999
50644911	50644933	14	-	27760321	MOLM13	viability	TGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.314096878541798	[332,348]	[100,201]	-2	hSpCas9	negative selection	5438458
50645000	50645022	14	+	27760321	MOLM13	viability	CAACTCTCCCAATACCTACGGG	SAV1	ENSG00000151748	0.30307359211793394	[181,200]	[264,22]	2	hSpCas9	negative selection	5438459
50665194	50665216	14	-	27760321	MOLM13	viability	CAAAGAATGCCACAGAATCAGG	SAV1	ENSG00000151748	0.8880525076599175	[342,242]	[461,166]	6	hSpCas9	negative selection	5438460
50665483	50665505	14	+	27760321	MOLM13	viability	TGGAGTTCTAAGGAAACTCTGG	SAV1	ENSG00000151748	0.15803266313973974	[169,183]	[210,27]	1	hSpCas9	negative selection	5438461
50665590	50665612	14	+	27760321	MOLM13	viability	GACCATGCCGGATGAATGAAGG	SAV1	ENSG00000151748	0.756066567554547	[528,447]	[761,209]	5	hSpCas9	negative selection	5438462
50668275	50668298	14	-	27661255	K562	viability	GGTTATTCGGCGGCCCGCGGCGG	SAV1	ENSG00000151748	0.16669825504373148	[979,1402]	[1101,1026]	6	dCas9-KRAB	negative selection	5509404
50668296	50668319	14	-	27661255	K562	viability	GGCGGCGGCGGTAGTGGTAGCGG	SAV1	ENSG00000151748	-0.038424173610183576	[246,280]	[226,185]	-1	dCas9-KRAB	negative selection	5509405
50644804	50644827	14	-	27260156	BXPC3	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.3109578263951869	[672]	[920,775,823,976]	6	hSpCas9	negative selection	5568875
50640867	50640890	14	+	27260156	BXPC3	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.001832093632193832	[261]	[244,305,231,314]	0	hSpCas9	negative selection	5568876
50644846	50644869	14	-	27260156	BXPC3	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.30625635331170975	[202]	[141,124,261,162]	-6	hSpCas9	negative selection	5568877
50635308	50635331	14	+	27260156	BXPC3	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.009684109570332389	[1195]	[1185,1174,1419,1261]	0	hSpCas9	negative selection	5633129
50640765	50640788	14	+	27260156	BXPC3	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	-0.05747209958224153	[229]	[183,231,196,325]	-1	hSpCas9	negative selection	5633130
50635239	50635262	14	-	27260156	BXPC3	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.022375206630843136	[279]	[253,257,231,428]	0	hSpCas9	negative selection	5633131
50644804	50644827	14	-	27260156	A673	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.12040095610212043	[672]	[900,911,868,828]	3	hSpCas9	negative selection	5690126
50640867	50640890	14	+	27260156	A673	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.0016446433645715963	[261]	[330,358,275,292]	0	hSpCas9	negative selection	5690127
50644846	50644869	14	-	27260156	A673	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.03433141722552957	[202]	[316,225,202,213]	-1	hSpCas9	negative selection	5690128
50635308	50635331	14	+	27260156	A673	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.0745008925543571	[1195]	[1368,1236,1284,1577]	-2	hSpCas9	negative selection	5754380
50640765	50640788	14	+	27260156	A673	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.13101592457098088	[229]	[370,366,240,232]	3	hSpCas9	negative selection	5754381
50635239	50635262	14	-	27260156	A673	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.023306845525261743	[279]	[298,334,295,436]	0	hSpCas9	negative selection	5754382
50644804	50644827	14	-	27260156	A375	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.5424763306655026	[672]	[1205,1460,923,1040]	7	hSpCas9	negative selection	5811377
50640867	50640890	14	+	27260156	A375	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.9092624985238188	[261]	[421,633,702,547]	9	hSpCas9	negative selection	5811378
50644846	50644869	14	-	27260156	A375	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	0.5443645745741591	[202]	[270,368,301,431]	7	hSpCas9	negative selection	5811379
50635308	50635331	14	+	27260156	A375	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.9290562071458608	[1195]	[2601,2824,2312,2883]	9	hSpCas9	negative selection	5875631
50640765	50640788	14	+	27260156	A375	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.5930589967933382	[229]	[486,317,454,353]	8	hSpCas9	negative selection	5875632
50635239	50635262	14	-	27260156	A375	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.11526712972254127	[279]	[308,252,337,299]	-2	hSpCas9	negative selection	5875633
50644804	50644827	14	-	27260156	COLO741	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.2818206366785526	[672]	[987,940,1188]	6	hSpCas9	negative selection	5932628
50640867	50640890	14	+	27260156	COLO741	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.11255919340944742	[261]	[482,347,270]	2	hSpCas9	negative selection	5932629
50644846	50644869	14	-	27260156	COLO741	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.33937209151287484	[202]	[318,141,165]	-6	hSpCas9	negative selection	5932630
50635308	50635331	14	+	27260156	COLO741	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.06112378507755056	[1195]	[1687,1445,1288]	-1	hSpCas9	negative selection	5996882
50640765	50640788	14	+	27260156	COLO741	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	-0.20889739540987118	[229]	[296,245,224]	-4	hSpCas9	negative selection	5996883
50635239	50635262	14	-	27260156	COLO741	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.07825834666884202	[279]	[457,246,321]	-2	hSpCas9	negative selection	5996884
50644804	50644827	14	-	27260156	CAL120	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.2502940630203663	[672]	[951,1125,904]	4	hSpCas9	negative selection	6053879
50640867	50640890	14	+	27260156	CAL120	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.4478869373095623	[261]	[726,291,358]	6	hSpCas9	negative selection	6053880
50644846	50644869	14	-	27260156	CAL120	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.5181201812039935	[202]	[197,137,195]	-6	hSpCas9	negative selection	6053881
50635308	50635331	14	+	27260156	CAL120	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.30662090290282507	[1195]	[1605,2145,1735]	4	hSpCas9	negative selection	6118133
50640765	50640788	14	+	27260156	CAL120	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	-0.512774282600339	[229]	[114,226,245]	-6	hSpCas9	negative selection	6118134
50635239	50635262	14	-	27260156	CAL120	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.30377489994616935	[279]	[939,230,199]	4	hSpCas9	negative selection	6118135
50644804	50644827	14	-	27260156	CADOES1	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.061890747291529324	[672]	[644,661,563,745]	1	hSpCas9	negative selection	6175130
50640867	50640890	14	+	27260156	CADOES1	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.03177922367303376	[261]	[141,289,303,216]	0	hSpCas9	negative selection	6175131
50644846	50644869	14	-	27260156	CADOES1	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	0.03530534110512962	[202]	[135,203,216,217]	0	hSpCas9	negative selection	6175132
50635308	50635331	14	+	27260156	CADOES1	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.012138533751264946	[1195]	[1077,1055,972,1312]	0	hSpCas9	negative selection	6239384
50640765	50640788	14	+	27260156	CADOES1	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.1543425523229527	[229]	[313,164,181,292]	2	hSpCas9	negative selection	6239385
50635239	50635262	14	-	27260156	CADOES1	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.015616177235359907	[279]	[395,161,211,259]	0	hSpCas9	negative selection	6239386
50644804	50644827	14	-	27260156	EWS502	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.11038111816914842	[672]	[678,740,834,837]	2	hSpCas9	negative selection	6296381
50640867	50640890	14	+	27260156	EWS502	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.00938715721507044	[261]	[287,272,231,324]	0	hSpCas9	negative selection	6296382
50644846	50644869	14	-	27260156	EWS502	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.4404342163079602	[202]	[79,250,161,144]	-6	hSpCas9	negative selection	6296383
50635308	50635331	14	+	27260156	EWS502	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.19352273721928603	[1195]	[1359,1822,1231,1359]	3	hSpCas9	negative selection	6360635
50640765	50640788	14	+	27260156	EWS502	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.033205986182514025	[229]	[172,227,305,303]	0	hSpCas9	negative selection	6360636
50635239	50635262	14	-	27260156	EWS502	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.3049025978264627	[279]	[278,238,196,238]	-5	hSpCas9	negative selection	6360637
50644804	50644827	14	-	27260156	EW8	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.09204776361537337	[672]	[686,431,535,686]	1	hSpCas9	negative selection	6417632
50640867	50640890	14	+	27260156	EW8	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.2891302476001649	[261]	[239,379,179,248]	5	hSpCas9	negative selection	6417633
50644846	50644869	14	-	27260156	EW8	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.10607795355833805	[202]	[127,135,122,225]	-2	hSpCas9	negative selection	6417634
50635308	50635331	14	+	27260156	EW8	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.16318195692842363	[1195]	[874,905,710,994]	-3	hSpCas9	negative selection	6481886
50640765	50640788	14	+	27260156	EW8	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.2106886853123089	[229]	[373,235,156,122]	4	hSpCas9	negative selection	6481887
50635239	50635262	14	-	27260156	EW8	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.18409799022060647	[279]	[233,285,126,167]	-3	hSpCas9	negative selection	6481888
50644804	50644827	14	-	27260156	CORL105	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.20065155369736465	[672]	[906,886,1031,815]	4	hSpCas9	negative selection	6538883
50640867	50640890	14	+	27260156	CORL105	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.025839050175106237	[261]	[358,255,370,274]	0	hSpCas9	negative selection	6538884
50644846	50644869	14	-	27260156	CORL105	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.3172107692471484	[202]	[178,185,274,135]	-5	hSpCas9	negative selection	6538885
50635308	50635331	14	+	27260156	CORL105	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.02256935051339526	[1195]	[1494,1280,1483,1275]	0	hSpCas9	negative selection	6603137
50640765	50640788	14	+	27260156	CORL105	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.2731999936699596	[229]	[209,249,342,497]	5	hSpCas9	negative selection	6603138
50635239	50635262	14	-	27260156	CORL105	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.30103660209589533	[279]	[289,418,192,148]	-5	hSpCas9	negative selection	6603139
50644804	50644827	14	-	27260156	HS294T	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.25124726169520695	[672]	[297,377,298,251]	3	hSpCas9	negative selection	6660134
50640867	50640890	14	+	27260156	HS294T	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.06352679435368791	[261]	[89,71,101,172]	0	hSpCas9	negative selection	6660135
50644846	50644869	14	-	27260156	HS294T	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-1.2534387711106414	[202]	[23,55,21,28]	-9	hSpCas9	negative selection	6660136
50635308	50635331	14	+	27260156	HS294T	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.3055710886836873	[1195]	[281,321,448,468]	-4	hSpCas9	negative selection	6724388
50640765	50640788	14	+	27260156	HS294T	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.22953553950605832	[229]	[76,108,159,66]	3	hSpCas9	negative selection	6724389
50635239	50635262	14	-	27260156	HS294T	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.23476427202445715	[279]	[101,88,87,86]	-3	hSpCas9	negative selection	6724390
50644804	50644827	14	-	27260156	HCC44	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.14405835895029506	[672]	[835,876,809,823]	2	hSpCas9	negative selection	6781385
50640867	50640890	14	+	27260156	HCC44	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.23949623515344554	[261]	[377,190,347,125]	-4	hSpCas9	negative selection	6781386
50644846	50644869	14	-	27260156	HCC44	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.6031890432039544	[202]	[153,130,141,176]	-7	hSpCas9	negative selection	6781387
50635308	50635331	14	+	27260156	HCC44	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.34503324455015294	[1195]	[903,1068,1328,981]	-5	hSpCas9	negative selection	6845639
50640765	50640788	14	+	27260156	HCC44	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.21795795370572224	[229]	[299,288,297,320]	3	hSpCas9	negative selection	6845640
50635239	50635262	14	-	27260156	HCC44	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.7672380162848128	[279]	[356,100,173,137]	-8	hSpCas9	negative selection	6845641
50644804	50644827	14	-	27260156	G402	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.30389763294655114	[672]	[979,1407,813,873]	4	hSpCas9	negative selection	6902636
50640867	50640890	14	+	27260156	G402	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.0164158272581586	[261]	[304,335,214,428]	0	hSpCas9	negative selection	6902637
50644846	50644869	14	-	27260156	G402	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.03278107545873832	[202]	[162,440,317,54]	0	hSpCas9	negative selection	6902638
50635308	50635331	14	+	27260156	G402	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.09508315037710435	[1195]	[2771,1484,1177,992]	1	hSpCas9	negative selection	6966890
50640765	50640788	14	+	27260156	G402	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.552656852293206	[229]	[313,341,498,468]	7	hSpCas9	negative selection	6966891
50635239	50635262	14	-	27260156	G402	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.07291508757435372	[279]	[248,525,489,173]	0	hSpCas9	negative selection	6966892
50644804	50644827	14	-	27260156	L33	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.24752177147019705	[672]	[914,286,522,745]	5	hSpCas9	negative selection	7023887
50640867	50640890	14	+	27260156	L33	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.0896897516918902	[261]	[255,108,188,292]	2	hSpCas9	negative selection	7023888
50644846	50644869	14	-	27260156	L33	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.40120491073475817	[202]	[181,64,67,164]	-7	hSpCas9	negative selection	7023889
50635308	50635331	14	+	27260156	L33	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.09291238795484147	[1195]	[1089,484,678,1131]	-2	hSpCas9	negative selection	7088141
50640765	50640788	14	+	27260156	L33	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.16739043760328953	[229]	[304,88,177,226]	3	hSpCas9	negative selection	7088142
50635239	50635262	14	-	27260156	L33	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.11968636650138265	[279]	[409,86,185,295]	2	hSpCas9	negative selection	7088143
50644804	50644827	14	-	27260156	K562	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.45955711663268617	[672]	[581,699,721,1205]	6	hSpCas9	negative selection	7145138
50640867	50640890	14	+	27260156	K562	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.02352007604204731	[261]	[264,166,396,99]	0	hSpCas9	negative selection	7145139
50644846	50644869	14	-	27260156	K562	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	0.3790266844727783	[202]	[312,161,278,189]	5	hSpCas9	negative selection	7145140
50635308	50635331	14	+	27260156	K562	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.17078077049400875	[1195]	[1055,1385,1158,1173]	2	hSpCas9	negative selection	7209392
50640765	50640788	14	+	27260156	K562	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.5452881939273291	[229]	[293,357,195,339]	7	hSpCas9	negative selection	7209393
50635239	50635262	14	-	27260156	K562	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.24732305408869015	[279]	[160,160,317,191]	-3	hSpCas9	negative selection	7209394
50644804	50644827	14	-	27260156	HT29	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.3653442314152877	[672]	[1259,1190,1013,801]	7	hSpCas9	negative selection	7266389
50640867	50640890	14	+	27260156	HT29	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.2560483896463249	[261]	[327,452,432,314]	5	hSpCas9	negative selection	7266390
50644846	50644869	14	-	27260156	HT29	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.10524603618045036	[202]	[224,309,260,137]	-2	hSpCas9	negative selection	7266391
50635308	50635331	14	+	27260156	HT29	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.05455535943095602	[1195]	[1618,1792,1495,1192]	1	hSpCas9	negative selection	7330643
50640765	50640788	14	+	27260156	HT29	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.16958950138741857	[229]	[471,271,303,226]	3	hSpCas9	negative selection	7330644
50635239	50635262	14	-	27260156	HT29	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.2146115443510871	[279]	[377,442,293,456]	4	hSpCas9	negative selection	7330645
50644804	50644827	14	-	27260156	MHHES1	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.015203070659977391	[672]	[960,772,679,676]	0	hSpCas9	negative selection	7387640
50640867	50640890	14	+	27260156	MHHES1	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.09853799392343032	[261]	[147,306,220,381]	-2	hSpCas9	negative selection	7387641
50644846	50644869	14	-	27260156	MHHES1	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.6393479428134494	[202]	[72,198,200,114]	-8	hSpCas9	negative selection	7387642
50635308	50635331	14	+	27260156	MHHES1	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.09523046700623583	[1195]	[1560,1426,1166,978]	-2	hSpCas9	negative selection	7451894
50640765	50640788	14	+	27260156	MHHES1	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.37468721840082586	[229]	[296,467,466,155]	6	hSpCas9	negative selection	7451895
50635239	50635262	14	-	27260156	MHHES1	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.08970633782722592	[279]	[372,316,437,233]	1	hSpCas9	negative selection	7451896
50644804	50644827	14	-	27260156	MEWO	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.13191809381775277	[672]	[860,638,602]	3	hSpCas9	negative selection	7508891
50640867	50640890	14	+	27260156	MEWO	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.6559705846883249	[261]	[308,309,524]	9	hSpCas9	negative selection	7508892
50644846	50644869	14	-	27260156	MEWO	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.08724152062427004	[202]	[157,231,141]	-2	hSpCas9	negative selection	7508893
50635308	50635331	14	+	27260156	MEWO	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.23661571271446724	[1195]	[1278,1142,1525]	5	hSpCas9	negative selection	7573145
50640765	50640788	14	+	27260156	MEWO	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	-0.13059454762024347	[229]	[254,185,159]	-3	hSpCas9	negative selection	7573146
50635239	50635262	14	-	27260156	MEWO	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.5802357474790879	[279]	[212,157,161]	-8	hSpCas9	negative selection	7573147
50644804	50644827	14	-	27260156	LNCAPCLONEFGC	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.309025537097834	[672]	[682,778,873,701]	5	hSpCas9	negative selection	7630142
50640867	50640890	14	+	27260156	LNCAPCLONEFGC	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.28008055679475163	[261]	[321,237,306,290]	4	hSpCas9	negative selection	7630143
50644846	50644869	14	-	27260156	LNCAPCLONEFGC	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.4212947348515672	[202]	[107,57,170,222]	-6	hSpCas9	negative selection	7630144
50635308	50635331	14	+	27260156	LNCAPCLONEFGC	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.20701179494853572	[1195]	[869,1126,954,792]	-3	hSpCas9	negative selection	7694396
50640765	50640788	14	+	27260156	LNCAPCLONEFGC	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.443442177460202	[229]	[256,302,341,238]	7	hSpCas9	negative selection	7694397
50635239	50635262	14	-	27260156	LNCAPCLONEFGC	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.2940865696075693	[279]	[142,269,210,200]	-4	hSpCas9	negative selection	7694398
50644804	50644827	14	-	27260156	PANC0327	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.29798753732402783	[672]	[633,893,738,643]	4	hSpCas9	negative selection	7751393
50640867	50640890	14	+	27260156	PANC0327	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.16003686165977649	[261]	[306,192,100,241]	-2	hSpCas9	negative selection	7751394
50644846	50644869	14	-	27260156	PANC0327	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	0.2357969066945622	[202]	[161,382,104,172]	3	hSpCas9	negative selection	7751395
50635308	50635331	14	+	27260156	PANC0327	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.21000651773379908	[1195]	[1862,1000,881,1249]	3	hSpCas9	negative selection	7815647
50640765	50640788	14	+	27260156	PANC0327	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.2771455459875488	[229]	[285,305,275,117]	4	hSpCas9	negative selection	7815648
50635239	50635262	14	-	27260156	PANC0327	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.0673924119601178	[279]	[199,209,305,327]	1	hSpCas9	negative selection	7815649
50644804	50644827	14	-	27260156	NCIH2009	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.2579767440289934	[672]	[1184,862,1339]	3	hSpCas9	negative selection	7872644
50640867	50640890	14	+	27260156	NCIH2009	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.3032443070483931	[261]	[517,527,319]	4	hSpCas9	negative selection	7872645
50644846	50644869	14	-	27260156	NCIH2009	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.4506407007915634	[202]	[268,118,247]	-5	hSpCas9	negative selection	7872646
50635308	50635331	14	+	27260156	NCIH2009	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.24960557742578304	[1195]	[2263,1948,1798]	3	hSpCas9	negative selection	7936898
50640765	50640788	14	+	27260156	NCIH2009	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.24378972283618605	[229]	[377,290,472]	3	hSpCas9	negative selection	7936899
50635239	50635262	14	-	27260156	NCIH2009	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.29488160360142596	[279]	[393,312,717]	4	hSpCas9	negative selection	7936900
50644804	50644827	14	-	27260156	NCIH1373	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.2905889399092373	[672]	[1036,957,845,224]	3	hSpCas9	negative selection	7993895
50640867	50640890	14	+	27260156	NCIH1373	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.37923240376036427	[261]	[224,221,212,63]	-4	hSpCas9	negative selection	7993896
50644846	50644869	14	-	27260156	NCIH1373	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	0.05441220132529945	[202]	[176,16,581,44]	0	hSpCas9	negative selection	7993897
50635308	50635331	14	+	27260156	NCIH1373	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.20996642004087906	[1195]	[911,1034,1132,406]	-2	hSpCas9	negative selection	8058149
50640765	50640788	14	+	27260156	NCIH1373	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.010951158021143215	[229]	[214,207,257,94]	0	hSpCas9	negative selection	8058150
50635239	50635262	14	-	27260156	NCIH1373	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.5368491347794203	[279]	[109,155,108,130]	-5	hSpCas9	negative selection	8058151
50644804	50644827	14	-	27260156	PATU8902	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.4176800222359729	[672]	[1444,1441,709,1578]	4	hSpCas9	negative selection	8115146
50640867	50640890	14	+	27260156	PATU8902	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.08478011893003734	[261]	[253,481,249,422]	-1	hSpCas9	negative selection	8115147
50644846	50644869	14	-	27260156	PATU8902	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.7601777358859454	[202]	[49,131,211,274]	-6	hSpCas9	negative selection	8115148
50635308	50635331	14	+	27260156	PATU8902	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.48940516943673484	[1195]	[1373,641,1308,1400]	-5	hSpCas9	negative selection	8179400
50640765	50640788	14	+	27260156	PATU8902	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	-0.44825128701542694	[229]	[266,325,90,297]	-4	hSpCas9	negative selection	8179401
50635239	50635262	14	-	27260156	PATU8902	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.04088690034148523	[279]	[455,207,577,195]	0	hSpCas9	negative selection	8179402
50644804	50644827	14	-	27260156	PANC1	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.4817188471955133	[672]	[790,1159,780,591]	7	hSpCas9	negative selection	8236397
50640867	50640890	14	+	27260156	PANC1	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.2543144024948266	[261]	[213,463,310,142]	4	hSpCas9	negative selection	8236398
50644846	50644869	14	-	27260156	PANC1	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.16363088368130851	[202]	[86,162,233,141]	-3	hSpCas9	negative selection	8236399
50635308	50635331	14	+	27260156	PANC1	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.25981649859438116	[1195]	[1103,1350,1229,1239]	4	hSpCas9	negative selection	8300651
50640765	50640788	14	+	27260156	PANC1	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.09903032127130973	[229]	[248,224,156,212]	1	hSpCas9	negative selection	8300652
50635239	50635262	14	-	27260156	PANC1	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.02527523327407588	[279]	[209,371,278,155]	0	hSpCas9	negative selection	8300653
50644804	50644827	14	-	27260156	PANC0813	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.12152537824691656	[672]	[812,956,890,777]	2	hSpCas9	negative selection	8357648
50640867	50640890	14	+	27260156	PANC0813	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.05867136567997622	[261]	[454,200,401,240]	1	hSpCas9	negative selection	8357649
50644846	50644869	14	-	27260156	PANC0813	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.47422808192646837	[202]	[163,136,95,281]	-6	hSpCas9	negative selection	8357650
50635308	50635331	14	+	27260156	PANC0813	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.21400108742409452	[1195]	[1603,1398,2081,1440]	3	hSpCas9	negative selection	8421902
50640765	50640788	14	+	27260156	PANC0813	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.20793323792327223	[229]	[390,331,381,158]	3	hSpCas9	negative selection	8421903
50635239	50635262	14	-	27260156	PANC0813	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.28215340112168297	[279]	[440,102,121,421]	-4	hSpCas9	negative selection	8421904
50644804	50644827	14	-	27260156	RDES	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.287779401048612	[672]	[711,936,1093,1086]	4	hSpCas9	negative selection	8478899
50640867	50640890	14	+	27260156	RDES	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.20507670231684316	[261]	[344,342,356,330]	3	hSpCas9	negative selection	8478900
50644846	50644869	14	-	27260156	RDES	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.07539288300888791	[202]	[193,218,196,283]	-1	hSpCas9	negative selection	8478901
50635308	50635331	14	+	27260156	RDES	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.013972508831108232	[1195]	[1089,1335,1550,1652]	0	hSpCas9	negative selection	8543153
50640765	50640788	14	+	27260156	RDES	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.5354488477572693	[229]	[301,399,333,520]	8	hSpCas9	negative selection	8543154
50635239	50635262	14	-	27260156	RDES	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.052171413767704955	[279]	[236,296,336,392]	-1	hSpCas9	negative selection	8543155
50644804	50644827	14	-	27260156	PC3	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.11156520476546605	[672]	[404,700,1386,742]	2	hSpCas9	negative selection	8600150
50640867	50640890	14	+	27260156	PC3	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.0033390845411701564	[261]	[163,237,286,386]	0	hSpCas9	negative selection	8600151
50644846	50644869	14	-	27260156	PC3	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	0.24430921138540218	[202]	[230,206,241,250]	5	hSpCas9	negative selection	8600152
50635308	50635331	14	+	27260156	PC3	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.35902572639397135	[1195]	[692,886,1353,949]	-7	hSpCas9	negative selection	8664404
50640765	50640788	14	+	27260156	PC3	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	-0.1272651394975417	[229]	[102,162,516,209]	-3	hSpCas9	negative selection	8664405
50635239	50635262	14	-	27260156	PC3	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.5556562009261418	[279]	[111,147,354,229]	-8	hSpCas9	negative selection	8664406
50644804	50644827	14	-	27260156	PATU8988T	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.11929756212743947	[672]	[607,1282,357,628]	2	hSpCas9	negative selection	8721401
50640867	50640890	14	+	27260156	PATU8988T	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.5952972650083258	[261]	[483,391,256,400]	8	hSpCas9	negative selection	8721402
50644846	50644869	14	-	27260156	PATU8988T	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.007846055612912295	[202]	[172,200,178,230]	0	hSpCas9	negative selection	8721403
50635308	50635331	14	+	27260156	PATU8988T	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.016029473717669607	[1195]	[1102,1157,1048,1381]	0	hSpCas9	negative selection	8785655
50640765	50640788	14	+	27260156	PATU8988T	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	-0.10342808474869636	[229]	[244,116,253,201]	-2	hSpCas9	negative selection	8785656
50635239	50635262	14	-	27260156	PATU8988T	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.48705278335352	[279]	[210,227,183,148]	-7	hSpCas9	negative selection	8785657
50644804	50644827	14	-	27260156	T47D	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.04702295623136188	[672]	[745,782,726,992]	1	hSpCas9	negative selection	8842652
50640867	50640890	14	+	27260156	T47D	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.2121908204278663	[261]	[393,367,318,331]	4	hSpCas9	negative selection	8842653
50644846	50644869	14	-	27260156	T47D	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.11238581352891708	[202]	[210,204,216,243]	-3	hSpCas9	negative selection	8842654
50635308	50635331	14	+	27260156	T47D	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.07328051141858327	[1195]	[1328,1257,1340,1375]	-2	hSpCas9	negative selection	8906906
50640765	50640788	14	+	27260156	T47D	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	-0.01925580382631753	[229]	[279,220,271,288]	0	hSpCas9	negative selection	8906907
50635239	50635262	14	-	27260156	T47D	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.3637003486350442	[279]	[308,176,187,350]	-7	hSpCas9	negative selection	8906908
50644804	50644827	14	-	27260156	SU8686	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.4437873100459966	[672]	[866,774,1030,988]	7	hSpCas9	negative selection	8963903
50640867	50640890	14	+	27260156	SU8686	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.23565015455339744	[261]	[343,233,312,340]	4	hSpCas9	negative selection	8963904
50644846	50644869	14	-	27260156	SU8686	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.46378587332459476	[202]	[128,176,96,181]	-6	hSpCas9	negative selection	8963905
50635308	50635331	14	+	27260156	SU8686	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.0032488548704019404	[1195]	[1002,1126,1337,1307]	0	hSpCas9	negative selection	9028157
50640765	50640788	14	+	27260156	SU8686	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.006832508796729364	[229]	[215,246,175,281]	0	hSpCas9	negative selection	9028158
50635239	50635262	14	-	27260156	SU8686	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.4332047674969576	[279]	[180,175,211,268]	-6	hSpCas9	negative selection	9028159
50644804	50644827	14	-	27260156	SKES1	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.11924755263815912	[672]	[884,801,680,588]	2	hSpCas9	negative selection	9085154
50640867	50640890	14	+	27260156	SKES1	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.2614504808752406	[261]	[386,377,248,260]	5	hSpCas9	negative selection	9085155
50644846	50644869	14	-	27260156	SKES1	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.14603913535695412	[202]	[302,123,126,185]	-3	hSpCas9	negative selection	9085156
50635308	50635331	14	+	27260156	SKES1	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.026308741408306746	[1195]	[1256,1266,1241,955]	0	hSpCas9	negative selection	9149408
50640765	50640788	14	+	27260156	SKES1	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.42205508432293637	[229]	[386,418,294,166]	8	hSpCas9	negative selection	9149409
50635239	50635262	14	-	27260156	SKES1	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.16630259136667203	[279]	[300,274,207,222]	-4	hSpCas9	negative selection	9149410
50644804	50644827	14	-	27260156	TOV112D	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.320967073661365	[672]	[1154,1247,651,448]	6	hSpCas9	negative selection	9206405
50640867	50640890	14	+	27260156	TOV112D	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.011144103210134149	[261]	[303,370,244,154]	0	hSpCas9	negative selection	9206406
50644846	50644869	14	-	27260156	TOV112D	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.4982348728337236	[202]	[111,222,138,118]	-7	hSpCas9	negative selection	9206407
50635308	50635331	14	+	27260156	TOV112D	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	0.30774313237433937	[1195]	[2101,1270,1678,892]	6	hSpCas9	negative selection	9270659
50640765	50640788	14	+	27260156	TOV112D	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.30506457423292266	[229]	[324,299,194,323]	6	hSpCas9	negative selection	9270660
50635239	50635262	14	-	27260156	TOV112D	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	0.023638876292686795	[279]	[255,260,313,299]	0	hSpCas9	negative selection	9270661
50644804	50644827	14	-	27260156	TC71	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.07104717515834502	[672]	[637,787,717,899]	1	hSpCas9	negative selection	9327656
50640867	50640890	14	+	27260156	TC71	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.050312571396076367	[261]	[270,394,212,286]	1	hSpCas9	negative selection	9327657
50644846	50644869	14	-	27260156	TC71	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.2002547290845611	[202]	[205,163,206,178]	-5	hSpCas9	negative selection	9327658
50635308	50635331	14	+	27260156	TC71	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.008821470364498873	[1195]	[1396,1196,1252,1245]	0	hSpCas9	negative selection	9391910
50640765	50640788	14	+	27260156	TC71	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.3078109728049897	[229]	[346,237,278,359]	7	hSpCas9	negative selection	9391911
50635239	50635262	14	-	27260156	TC71	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.13855150073675837	[279]	[273,279,232,306]	-4	hSpCas9	negative selection	9391912
50644804	50644827	14	-	27260156	TC32	viability	CGAGTTGAGTCATCCGAATTTGG	SAV1	ENSG00000151748	0.18345917470093986	[672]	[782,567,930,625]	3	hSpCas9	negative selection	9448907
50640867	50640890	14	+	27260156	TC32	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.08375502867627904	[261]	[247,203,309,170]	-1	hSpCas9	negative selection	9448908
50644846	50644869	14	-	27260156	TC32	viability	AGCCATCCTCTTGAGCGAGAAGG	SAV1	ENSG00000151748	-0.2815209383793822	[202]	[127,133,189,185]	-5	hSpCas9	negative selection	9448909
50635308	50635331	14	+	27260156	TC32	viability	AGAGCAACTTTAGCATTCCCTGG	SAV1	ENSG00000151748	-0.0988658513188021	[1195]	[1052,767,1322,1149]	-2	hSpCas9	negative selection	9513161
50640765	50640788	14	+	27260156	TC32	viability	GCGTAAACCTGAAGCCAGTCAGG	SAV1	ENSG00000151748	0.4801560887103815	[229]	[285,224,300,412]	7	hSpCas9	negative selection	9513162
50635239	50635262	14	-	27260156	TC32	viability	ACAAGCCCTTCTTACAGAGTTGG	SAV1	ENSG00000151748	-0.046832372622663265	[279]	[229,186,326,303]	-1	hSpCas9	negative selection	9513163
50635338	50635361	14	-	27869803	HPAFII	viability after 27 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.507827160430442	[129]	[118,78,NaN]	4	hSpCas9	negative selection	9551679
50640852	50640875	14	+	27869803	HPAFII	viability after 27 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	1.8651964104295637	[231]	[271,587,NaN]	9	hSpCas9	negative selection	9551680
50644819	50644842	14	+	27869803	HPAFII	viability after 27 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.4978961791324584	[203]	[187,120,NaN]	4	hSpCas9	negative selection	9551681
50644840	50644863	14	+	27869803	HPAFII	viability after 27 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.5070678250307084	[191]	[155,132,NaN]	4	hSpCas9	negative selection	9551682
50644911	50644934	14	-	27869803	HPAFII	viability after 27 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.17579385623439087	[337]	[179,217,NaN]	1	hSpCas9	negative selection	9551683
50635338	50635361	14	-	27869803	HPAFII	viability after 15 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.2064417335563944	[129]	[249,105,NaN]	2	hSpCas9	negative selection	9634128
50640852	50640875	14	+	27869803	HPAFII	viability after 15 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	1.033047739268949	[231]	[471,533,NaN]	9	hSpCas9	negative selection	9634129
50644819	50644842	14	+	27869803	HPAFII	viability after 15 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-0.40666742166724174	[203]	[239,118,NaN]	-4	hSpCas9	negative selection	9634130
50644840	50644863	14	+	27869803	HPAFII	viability after 15 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.980843492348072	[191]	[434,389,NaN]	9	hSpCas9	negative selection	9634131
50644911	50644934	14	-	27869803	HPAFII	viability after 15 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.2923981526909456	[337]	[295,296,NaN]	-3	hSpCas9	negative selection	9634132
50635338	50635361	14	-	27869803	ASPC1	viability after 36 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	-0.15122185882235417	[510]	[49,217,190]	-1	hSpCas9	negative selection	9716577
50640852	50640875	14	+	27869803	ASPC1	viability after 36 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	1.6663181897391133	[544]	[553,873,417]	9	hSpCas9	negative selection	9716578
50644819	50644842	14	+	27869803	ASPC1	viability after 36 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.6874725695615271	[554]	[218,641,111]	6	hSpCas9	negative selection	9716579
50644840	50644863	14	+	27869803	ASPC1	viability after 36 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.3029535374106123	[524]	[327,277,110]	3	hSpCas9	negative selection	9716580
50644911	50644934	14	-	27869803	ASPC1	viability after 36 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.4348881294912295	[800]	[243,479,386]	4	hSpCas9	negative selection	9716581
50635338	50635361	14	-	27869803	PATU8988S	viability after 35 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.5625585218197995	[353]	[238,181,NaN]	6	hSpCas9	negative selection	9799026
50640852	50640875	14	+	27869803	PATU8988S	viability after 35 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.07624099180005264	[536]	[233,221,NaN]	0	hSpCas9	negative selection	9799027
50644819	50644842	14	+	27869803	PATU8988S	viability after 35 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-0.7793329238005312	[487]	[119,108,NaN]	-6	hSpCas9	negative selection	9799028
50644840	50644863	14	+	27869803	PATU8988S	viability after 35 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	-0.508514544123291	[527]	[141,156,NaN]	-5	hSpCas9	negative selection	9799029
50644911	50644934	14	-	27869803	PATU8988S	viability after 35 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.9969799684816398	[685]	[108,167,NaN]	-7	hSpCas9	negative selection	9799030
50635338	50635361	14	-	27869803	PATU8988S	viability after 31 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.1296998944539256	[353]	[120,196,NaN]	1	hSpCas9	negative selection	9881475
50640852	50640875	14	+	27869803	PATU8988S	viability after 31 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	-0.06716213597533102	[536]	[133,293,NaN]	0	hSpCas9	negative selection	9881476
50644819	50644842	14	+	27869803	PATU8988S	viability after 31 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.4466766876074788	[487]	[273,253,NaN]	5	hSpCas9	negative selection	9881477
50644840	50644863	14	+	27869803	PATU8988S	viability after 31 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	-0.523449231663877	[527]	[105,197,NaN]	-5	hSpCas9	negative selection	9881478
50644911	50644934	14	-	27869803	PATU8988S	viability after 31 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.803562936896927	[685]	[150,163,NaN]	-7	hSpCas9	negative selection	9881479
50635338	50635361	14	-	27869803	HPAFII	viability after 35 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	0.22123966287493624	[129]	[103,45,NaN]	1	hSpCas9	negative selection	9963924
50640852	50640875	14	+	27869803	HPAFII	viability after 35 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	2.3466781666992484	[231]	[230,1009,NaN]	9	hSpCas9	negative selection	9963925
50644819	50644842	14	+	27869803	HPAFII	viability after 35 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.8576855027984567	[203]	[244,121,NaN]	5	hSpCas9	negative selection	9963926
50644840	50644863	14	+	27869803	HPAFII	viability after 35 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.6732872464480485	[191]	[162,145,NaN]	4	hSpCas9	negative selection	9963927
50644911	50644934	14	-	27869803	HPAFII	viability after 35 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.41384900604272307	[337]	[147,317,NaN]	2	hSpCas9	negative selection	9963928
50635338	50635361	14	-	27869803	HPAFII	viability after 31 days	ACTCTTCCAGCTGGCTGACCTGG	SAV1	ENSG00000151748	-0.21286214052154273	[129]	[72,51,NaN]	-1	hSpCas9	negative selection	10046373
50640852	50640875	14	+	27869803	HPAFII	viability after 31 days	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	2.0624362407037977	[231]	[249,863,NaN]	9	hSpCas9	negative selection	10046374
50644819	50644842	14	+	27869803	HPAFII	viability after 31 days	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.6084424043691532	[203]	[197,148,NaN]	4	hSpCas9	negative selection	10046375
50644840	50644863	14	+	27869803	HPAFII	viability after 31 days	GGAAGTCCTTCTCGCTCAAGAGG	SAV1	ENSG00000151748	0.8823899284661281	[191]	[223,170,NaN]	6	hSpCas9	negative selection	10046376
50644911	50644934	14	-	27869803	HPAFII	viability after 31 days	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.6022020620980466	[337]	[219,361,NaN]	4	hSpCas9	negative selection	10046377
50667864	50667887	14	+	28162770	P31FUJ	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.22492510801066978	[307]	[422]	2	hSpCas9	negative selection	10230024
50644939	50644962	14	-	28162770	P31FUJ	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.05174243010453017	[1164]	[1418]	0	hSpCas9	negative selection	10230025
50644819	50644842	14	+	28162770	P31FUJ	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.5261896960818264	[220]	[373]	6	hSpCas9	negative selection	10230026
50640867	50640890	14	+	28162770	P31FUJ	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.9447742331838105	[396]	[897]	9	hSpCas9	negative selection	10230027
50640852	50640875	14	+	28162770	P31FUJ	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.7123358605511029	[66]	[128]	7	hSpCas9	negative selection	10230028
50644911	50644934	14	-	28162770	P31FUJ	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.06213181672924452	[214]	[241]	0	hSpCas9	negative selection	10230029
50644834	50644857	14	-	28162770	P31FUJ	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.25936620063491833	[304]	[428]	3	hSpCas9	negative selection	10230030
50644734	50644757	14	+	28162770	P31FUJ	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	1.1056770667368316	[207]	[525]	9	hSpCas9	negative selection	10230031
50640805	50640828	14	+	28162770	P31FUJ	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	0.29504965977200026	[291]	[420]	3	hSpCas9	negative selection	10230032
50644928	50644951	14	+	28162770	P31FUJ	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	1.027433568066742	[85]	[205]	9	hSpCas9	negative selection	10230033
50667864	50667887	14	+	28162770	TF1	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10399390
50644939	50644962	14	-	28162770	TF1	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	NaN	[NaN]	[1531]	1	hSpCas9	negative selection	10399391
50644819	50644842	14	+	28162770	TF1	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10399392
50640867	50640890	14	+	28162770	TF1	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	NaN	[NaN]	[519]	1	hSpCas9	negative selection	10399393
50640852	50640875	14	+	28162770	TF1	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	NaN	[NaN]	[126]	1	hSpCas9	negative selection	10399394
50644911	50644934	14	-	28162770	TF1	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	NaN	[NaN]	[180]	1	hSpCas9	negative selection	10399395
50644834	50644857	14	-	28162770	TF1	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	NaN	[NaN]	[690]	1	hSpCas9	negative selection	10399396
50644734	50644757	14	+	28162770	TF1	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10399397
50640805	50640828	14	+	28162770	TF1	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	NaN	[NaN]	[358]	1	hSpCas9	negative selection	10399398
50644928	50644951	14	+	28162770	TF1	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10399399
50667864	50667887	14	+	28162770	SKM1	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	1.0511284916858377	[97]	[358]	8	hSpCas9	negative selection	10568756
50644939	50644962	14	-	28162770	SKM1	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.5031170248688546	[270]	[678]	5	hSpCas9	negative selection	10568757
50644819	50644842	14	+	28162770	SKM1	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.4003907233144425	[59]	[139]	4	hSpCas9	negative selection	10568758
50640867	50640890	14	+	28162770	SKM1	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	1.000264933439527	[109]	[388]	8	hSpCas9	negative selection	10568759
50640852	50640875	14	+	28162770	SKM1	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.7783908432687566	[30]	[93]	7	hSpCas9	negative selection	10568760
50644911	50644934	14	-	28162770	SKM1	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.7813393320140053	[51]	[157]	7	hSpCas9	negative selection	10568761
50644834	50644857	14	-	28162770	SKM1	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.4285417636285914	[57]	[137]	4	hSpCas9	negative selection	10568762
50644734	50644757	14	+	28162770	SKM1	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	1.0682101564398825	[57]	[214]	8	hSpCas9	negative selection	10568763
50640805	50640828	14	+	28162770	SKM1	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	0.17799830197799468	[56]	[113]	1	hSpCas9	negative selection	10568764
50644928	50644951	14	+	28162770	SKM1	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	0.3656253051537657	[17]	[40]	3	hSpCas9	negative selection	10568765
50667864	50667887	14	+	28162770	SKM1	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	1.0511284916858377	[97]	[358]	8	hSpCas9	negative selection	10738122
50644939	50644962	14	-	28162770	SKM1	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.5031170248688546	[270]	[678]	5	hSpCas9	negative selection	10738123
50644819	50644842	14	+	28162770	SKM1	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.4003907233144425	[59]	[139]	4	hSpCas9	negative selection	10738124
50640867	50640890	14	+	28162770	SKM1	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	1.000264933439527	[109]	[388]	8	hSpCas9	negative selection	10738125
50640852	50640875	14	+	28162770	SKM1	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.7783908432687566	[30]	[93]	7	hSpCas9	negative selection	10738126
50644911	50644934	14	-	28162770	SKM1	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.7813393320140053	[51]	[157]	7	hSpCas9	negative selection	10738127
50644834	50644857	14	-	28162770	SKM1	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.4285417636285914	[57]	[137]	4	hSpCas9	negative selection	10738128
50644734	50644757	14	+	28162770	SKM1	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	1.0682101564398825	[57]	[214]	8	hSpCas9	negative selection	10738129
50640805	50640828	14	+	28162770	SKM1	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	0.17799830197799468	[56]	[113]	1	hSpCas9	negative selection	10738130
50644928	50644951	14	+	28162770	SKM1	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	0.3656253051537657	[17]	[40]	3	hSpCas9	negative selection	10738131
50667864	50667887	14	+	28162770	PL21	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.41313333782351824	[351]	[203]	3	hSpCas9	negative selection	10907488
50644939	50644962	14	-	28162770	PL21	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.9219454014845208	[860]	[709]	7	hSpCas9	negative selection	10907489
50644819	50644842	14	+	28162770	PL21	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.23256109218169774	[263]	[134]	2	hSpCas9	negative selection	10907490
50640867	50640890	14	+	28162770	PL21	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.710754773750395	[437]	[311]	6	hSpCas9	negative selection	10907491
50640852	50640875	14	+	28162770	PL21	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.6595712331266175	[111]	[76]	6	hSpCas9	negative selection	10907492
50644911	50644934	14	-	28162770	PL21	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	1.501966503320173	[158]	[195]	9	hSpCas9	negative selection	10907493
50644834	50644857	14	-	28162770	PL21	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.018809849774758303	[253]	[111]	0	hSpCas9	negative selection	10907494
50644734	50644757	14	+	28162770	PL21	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	-0.21736614038027335	[194]	[72]	-1	hSpCas9	negative selection	10907495
50640805	50640828	14	+	28162770	PL21	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	1.0846623970693843	[142]	[131]	8	hSpCas9	negative selection	10907496
50644928	50644951	14	+	28162770	PL21	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	0.36786706022738636	[72]	[40]	3	hSpCas9	negative selection	10907497
50667864	50667887	14	+	28162770	P31FUJ	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.22492510801066978	[307]	[422]	2	hSpCas9	negative selection	11076854
50644939	50644962	14	-	28162770	P31FUJ	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.05174243010453017	[1164]	[1418]	0	hSpCas9	negative selection	11076855
50644819	50644842	14	+	28162770	P31FUJ	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.5261896960818264	[220]	[373]	6	hSpCas9	negative selection	11076856
50640867	50640890	14	+	28162770	P31FUJ	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.9447742331838105	[396]	[897]	9	hSpCas9	negative selection	11076857
50640852	50640875	14	+	28162770	P31FUJ	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.7123358605511029	[66]	[128]	7	hSpCas9	negative selection	11076858
50644911	50644934	14	-	28162770	P31FUJ	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.06213181672924452	[214]	[241]	0	hSpCas9	negative selection	11076859
50644834	50644857	14	-	28162770	P31FUJ	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.25936620063491833	[304]	[428]	3	hSpCas9	negative selection	11076860
50644734	50644757	14	+	28162770	P31FUJ	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	1.1056770667368316	[207]	[525]	9	hSpCas9	negative selection	11076861
50640805	50640828	14	+	28162770	P31FUJ	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	0.29504965977200026	[291]	[420]	3	hSpCas9	negative selection	11076862
50644928	50644951	14	+	28162770	P31FUJ	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	1.027433568066742	[85]	[205]	9	hSpCas9	negative selection	11076863
50667864	50667887	14	+	28162770	OCIAML5	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	-0.1631952648988359	[182]	[294]	-1	hSpCas9	negative selection	11246220
50644939	50644962	14	-	28162770	OCIAML5	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.5854700686511558	[675]	[1830]	5	hSpCas9	negative selection	11246221
50644819	50644842	14	+	28162770	OCIAML5	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.4554653029468617	[140]	[348]	4	hSpCas9	negative selection	11246222
50640867	50640890	14	+	28162770	OCIAML5	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.7927457848846803	[180]	[565]	7	hSpCas9	negative selection	11246223
50640852	50640875	14	+	28162770	OCIAML5	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	-0.19555080911780687	[58]	[92]	-1	hSpCas9	negative selection	11246224
50644911	50644934	14	-	28162770	OCIAML5	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.15621996402338326	[120]	[195]	-1	hSpCas9	negative selection	11246225
50644834	50644857	14	-	28162770	OCIAML5	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.8078579875383813	[149]	[473]	7	hSpCas9	negative selection	11246226
50644734	50644757	14	+	28162770	OCIAML5	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	0.8493054219724698	[118]	[386]	7	hSpCas9	negative selection	11246227
50640805	50640828	14	+	28162770	OCIAML5	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	0.3717084045225698	[148]	[347]	3	hSpCas9	negative selection	11246228
50644928	50644951	14	+	28162770	OCIAML5	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	0.27346431121986203	[32]	[71]	2	hSpCas9	negative selection	11246229
50667864	50667887	14	+	28162770	EOL1	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.5699749135555849	[513]	[401]	5	hSpCas9	negative selection	11415586
50644939	50644962	14	-	28162770	EOL1	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.8159065115667108	[1350]	[1252]	7	hSpCas9	negative selection	11415587
50644819	50644842	14	+	28162770	EOL1	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-0.23217773211691864	[407]	[182]	-2	hSpCas9	negative selection	11415588
50640867	50640890	14	+	28162770	EOL1	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.5985866703705145	[805]	[642]	5	hSpCas9	negative selection	11415589
50640852	50640875	14	+	28162770	EOL1	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.28231046549762917	[166]	[106]	2	hSpCas9	negative selection	11415590
50644911	50644934	14	-	28162770	EOL1	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.3110161186526075	[305]	[199]	3	hSpCas9	negative selection	11415591
50644834	50644857	14	-	28162770	EOL1	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	-0.00488164605690844	[378]	[198]	0	hSpCas9	negative selection	11415592
50644734	50644757	14	+	28162770	EOL1	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	0.4433117826148889	[274]	[196]	4	hSpCas9	negative selection	11415593
50640805	50640828	14	+	28162770	EOL1	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	-0.4655985521665985	[248]	[94]	-3	hSpCas9	negative selection	11415594
50644928	50644951	14	+	28162770	EOL1	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	-1.3758471617671866	[132]	[26]	-7	hSpCas9	negative selection	11415595
50667864	50667887	14	+	28162770	MOLM13	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.16060806262161798	[489]	[395]	1	hSpCas9	negative selection	11584952
50644939	50644962	14	-	28162770	MOLM13	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.2245201500632974	[1500]	[1267]	1	hSpCas9	negative selection	11584953
50644819	50644842	14	+	28162770	MOLM13	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.6793934867382907	[341]	[395]	5	hSpCas9	negative selection	11584954
50640867	50640890	14	+	28162770	MOLM13	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.5508644088023473	[624]	[661]	4	hSpCas9	negative selection	11584955
50640852	50640875	14	+	28162770	MOLM13	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.04014083051618089	[151]	[112]	0	hSpCas9	negative selection	11584956
50644911	50644934	14	-	28162770	MOLM13	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.30742470935133276	[284]	[254]	2	hSpCas9	negative selection	11584957
50644834	50644857	14	-	28162770	MOLM13	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	-0.02752153419828518	[405]	[287]	0	hSpCas9	negative selection	11584958
50644734	50644757	14	+	28162770	MOLM13	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	-1.388375140993972	[314]	[86]	-6	hSpCas9	negative selection	11584959
50640805	50640828	14	+	28162770	MOLM13	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	-0.33946554051302524	[405]	[231]	-2	hSpCas9	negative selection	11584960
50644928	50644951	14	+	28162770	MOLM13	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	0.3242985279157289	[94]	[85]	2	hSpCas9	negative selection	11584961
50667864	50667887	14	+	28162770	HEL	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.14240029542618682	[388]	[274]	1	hSpCas9	negative selection	11754318
50644939	50644962	14	-	28162770	HEL	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.22984469226132642	[1120]	[841]	1	hSpCas9	negative selection	11754319
50644819	50644842	14	+	28162770	HEL	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.03382159912747801	[333]	[218]	0	hSpCas9	negative selection	11754320
50640867	50640890	14	+	28162770	HEL	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.134006664151204	[477]	[278]	-1	hSpCas9	negative selection	11754321
50640852	50640875	14	+	28162770	HEL	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.586595753962823	[130]	[125]	5	hSpCas9	negative selection	11754322
50644911	50644934	14	-	28162770	HEL	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	0.369454329472806	[225]	[186]	3	hSpCas9	negative selection	11754323
50644834	50644857	14	-	28162770	HEL	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.2912664614989795	[295]	[231]	2	hSpCas9	negative selection	11754324
50644734	50644757	14	+	28162770	HEL	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	-0.7994834966047172	[249]	[91]	-5	hSpCas9	negative selection	11754325
50640805	50640828	14	+	28162770	HEL	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	-0.31584124061966223	[308]	[158]	-2	hSpCas9	negative selection	11754326
50644928	50644951	14	+	28162770	HEL	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	0.6788080867078787	[78]	[80]	6	hSpCas9	negative selection	11754327
50667864	50667887	14	+	28162770	MV411	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.27022941565601766	[313]	[318]	2	hSpCas9	negative selection	11923684
50644939	50644962	14	-	28162770	MV411	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.9585939585993764	[845]	[1384]	8	hSpCas9	negative selection	11923685
50644819	50644842	14	+	28162770	MV411	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-0.09169983413681015	[252]	[199]	0	hSpCas9	negative selection	11923686
50640867	50640890	14	+	28162770	MV411	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.9628124367283757	[376]	[618]	8	hSpCas9	negative selection	11923687
50640852	50640875	14	+	28162770	MV411	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.5668973900793879	[116]	[145]	5	hSpCas9	negative selection	11923688
50644911	50644934	14	-	28162770	MV411	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.5544353062584133	[196]	[112]	-4	hSpCas9	negative selection	11923689
50644834	50644857	14	-	28162770	MV411	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.7422022425323533	[241]	[340]	6	hSpCas9	negative selection	11923690
50644734	50644757	14	+	28162770	MV411	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	0.23075880963614492	[173]	[171]	2	hSpCas9	negative selection	11923691
50640805	50640828	14	+	28162770	MV411	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	0.7536229381198144	[206]	[293]	6	hSpCas9	negative selection	11923692
50644928	50644951	14	+	28162770	MV411	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	0.6122018435803955	[72]	[93]	5	hSpCas9	negative selection	11923693
50667864	50667887	14	+	28162770	MONOMAC1	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	-0.1074852620812613	[202]	[215]	-1	hSpCas9	negative selection	12093050
50644939	50644962	14	-	28162770	MONOMAC1	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.11259198287736494	[588]	[729]	1	hSpCas9	negative selection	12093051
50644819	50644842	14	+	28162770	MONOMAC1	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	-0.4455351597354671	[157]	[132]	-4	hSpCas9	negative selection	12093052
50640867	50640890	14	+	28162770	MONOMAC1	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	-0.22128439330623095	[299]	[294]	-2	hSpCas9	negative selection	12093053
50640852	50640875	14	+	28162770	MONOMAC1	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	-0.017713147614991764	[67]	[76]	0	hSpCas9	negative selection	12093054
50644911	50644934	14	-	28162770	MONOMAC1	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.6614404236593772	[108]	[78]	-5	hSpCas9	negative selection	12093055
50644834	50644857	14	-	28162770	MONOMAC1	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	1.0479292660129247	[153]	[364]	8	hSpCas9	negative selection	12093056
50644734	50644757	14	+	28162770	MONOMAC1	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	-0.3689895298488486	[88]	[78]	-3	hSpCas9	negative selection	12093057
50640805	50640828	14	+	28162770	MONOMAC1	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	-0.2602306735467476	[139]	[133]	-2	hSpCas9	negative selection	12093058
50644928	50644951	14	+	28162770	MONOMAC1	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	1.9072998127551821	[49]	[214]	9	hSpCas9	negative selection	12093059
50667864	50667887	14	+	28162770	OCIAML2	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	-0.18395257753785121	[57]	[282]	-1	hSpCas9	negative selection	12262416
50644939	50644962	14	-	28162770	OCIAML2	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.2631363805429143	[157]	[1050]	2	hSpCas9	negative selection	12262417
50644819	50644842	14	+	28162770	OCIAML2	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.43036016892667306	[48]	[365]	4	hSpCas9	negative selection	12262418
50640867	50640890	14	+	28162770	OCIAML2	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.20600250379138707	[93]	[600]	2	hSpCas9	negative selection	12262419
50640852	50640875	14	+	28162770	OCIAML2	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	0.12391872430819295	[24]	[150]	1	hSpCas9	negative selection	12262420
50644911	50644934	14	-	28162770	OCIAML2	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	1.1788002093571555	[30]	[388]	9	hSpCas9	negative selection	12262421
50644834	50644857	14	-	28162770	OCIAML2	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	-0.09717142971471673	[43]	[227]	-1	hSpCas9	negative selection	12262422
50644734	50644757	14	+	28162770	OCIAML2	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	0.6480146712564578	[34]	[303]	6	hSpCas9	negative selection	12262423
50640805	50640828	14	+	28162770	OCIAML2	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	-0.025844982569265283	[35]	[195]	0	hSpCas9	negative selection	12262424
50644928	50644951	14	+	28162770	OCIAML2	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	1.1276294980924528	[8]	[108]	9	hSpCas9	negative selection	12262425
50667864	50667887	14	+	28162770	OCIAML3	viability	TGACACTCACTCCGAAGCAGAGG	SAV1	ENSG00000151748	0.2710627795897284	[69]	[254]	2	hSpCas9	negative selection	12431782
50644939	50644962	14	-	28162770	OCIAML3	viability	GAAGATTTACCCCTTCCTCCTGG	SAV1	ENSG00000151748	0.3313398599919166	[232]	[884]	3	hSpCas9	negative selection	12431783
50644819	50644842	14	+	28162770	OCIAML3	viability	TCAACTCGTTCCCATCCAGGAGG	SAV1	ENSG00000151748	0.8804783240354234	[51]	[288]	7	hSpCas9	negative selection	12431784
50640867	50640890	14	+	28162770	OCIAML3	viability	GGAGGTGGTTGATCATACCGAGG	SAV1	ENSG00000151748	0.9228658705548236	[93]	[537]	7	hSpCas9	negative selection	12431785
50640852	50640875	14	+	28162770	OCIAML3	viability	GGCTGGTATGTGACAGGAGGTGG	SAV1	ENSG00000151748	1.8370421769433116	[13]	[150]	9	hSpCas9	negative selection	12431786
50644911	50644934	14	-	28162770	OCIAML3	viability	CTGTGGACTGGACAATGAGAGGG	SAV1	ENSG00000151748	-0.6788965379106762	[69]	[131]	-5	hSpCas9	negative selection	12431787
50644834	50644857	14	-	28162770	OCIAML3	viability	GAGCGAGAAGGACTTCCTCCTGG	SAV1	ENSG00000151748	0.12845838414692806	[69]	[230]	1	hSpCas9	negative selection	12431788
50644734	50644757	14	+	28162770	OCIAML3	viability	GATACTGTACCTAGGAGCACAGG	SAV1	ENSG00000151748	0.6283847810122847	[44]	[209]	6	hSpCas9	negative selection	12431789
50640805	50640828	14	+	28162770	OCIAML3	viability	ATGGATTTGCAGGTACCAGAAGG	SAV1	ENSG00000151748	-0.6318096730365474	[57]	[112]	-5	hSpCas9	negative selection	12431790
50644928	50644951	14	+	28162770	OCIAML3	viability	CCACAGACCAGCCAGGAGGAAGG	SAV1	ENSG00000151748	0.8711150903909896	[22]	[126]	7	hSpCas9	negative selection	12431791