Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:11280
• Symbol:SCN11A
• Description:sodium voltage-gated channel alpha subunit 11

DataSource: http://genomecrispr.dkfz.de/#!/results/SCN11A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
38894682	38894705	3	-	26472758	Jiyoye	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-0.170800688899176	[102]	[68]	-1	hSpCas9	negative selection	143009
38909119	38909142	3	+	26472758	Jiyoye	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	0.8477479728918547	[55]	[75]	6	hSpCas9	negative selection	143010
38950293	38950316	3	+	26472758	Jiyoye	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	0.5948023846816446	[35]	[40]	4	hSpCas9	negative selection	143011
38950187	38950210	3	+	26472758	Jiyoye	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	-0.05115368068426562	[326]	[237]	0	hSpCas9	negative selection	143012
38950168	38950191	3	+	26472758	Jiyoye	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	-0.7134543236796652	[186]	[85]	-5	hSpCas9	negative selection	143013
38925447	38925470	3	+	26472758	Jiyoye	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	-0.18284034694156837	[142]	[94]	-1	hSpCas9	negative selection	143014
38921167	38921190	3	+	26472758	Jiyoye	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	1.0690066456113	[66]	[105]	7	hSpCas9	negative selection	143015
38908996	38909019	3	-	26472758	Jiyoye	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-1.1442345595042562	[169]	[57]	-7	hSpCas9	negative selection	143016
38883318	38883341	3	+	26472758	Jiyoye	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	1.2331459817308243	[87]	[155]	7	hSpCas9	negative selection	143017
38950112	38950135	3	+	26472758	Jiyoye	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	0.15299189325434503	[259]	[217]	1	hSpCas9	negative selection	143018
38894682	38894705	3	-	26472758	KBM7	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-1.4345566178740767	[525,307]	[52,86]	-7	hSpCas9	negative selection	334127
38909119	38909142	3	+	26472758	KBM7	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	0.8605738250038723	[263,264]	[189,259]	8	hSpCas9	negative selection	334128
38950293	38950316	3	+	26472758	KBM7	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	0.16649490009625256	[166,152]	[103,66]	1	hSpCas9	negative selection	334129
38950187	38950210	3	+	26472758	KBM7	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.3584757373315609	[1111,767]	[590,529]	4	hSpCas9	negative selection	334130
38950168	38950191	3	+	26472758	KBM7	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	0.6433433553067553	[421,284]	[156,343]	7	hSpCas9	negative selection	334131
38925447	38925470	3	+	26472758	KBM7	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	0.15696542338710173	[421,408]	[217,218]	1	hSpCas9	negative selection	334132
38921167	38921190	3	+	26472758	KBM7	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	0.09846169285181955	[464,689]	[374,228]	1	hSpCas9	negative selection	334133
38908996	38909019	3	-	26472758	KBM7	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	0.3850895036017325	[615,549]	[401,317]	4	hSpCas9	negative selection	334134
38883318	38883341	3	+	26472758	KBM7	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	0.6650858732153777	[462,397]	[271,362]	7	hSpCas9	negative selection	334135
38950112	38950135	3	+	26472758	KBM7	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	0.509212852232791	[807,691]	[464,531]	5	hSpCas9	negative selection	334136
38894682	38894705	3	-	26472758	Raji	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-1.4603009739157211	[165]	[13]	-7	hSpCas9	negative selection	525245
38909119	38909142	3	+	26472758	Raji	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	0.6656780856326758	[181]	[66]	6	hSpCas9	negative selection	525246
38950293	38950316	3	+	26472758	Raji	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	-0.14054397806998598	[94]	[19]	-1	hSpCas9	negative selection	525247
38950187	38950210	3	+	26472758	Raji	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	-0.2655685625382296	[517]	[99]	-2	hSpCas9	negative selection	525248
38950168	38950191	3	+	26472758	Raji	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	0.07903890967963781	[256]	[62]	0	hSpCas9	negative selection	525249
38925447	38925470	3	+	26472758	Raji	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	0.13247451633642982	[113]	[28]	1	hSpCas9	negative selection	525250
38921167	38921190	3	+	26472758	Raji	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	-0.10042134973980199	[327]	[70]	-1	hSpCas9	negative selection	525251
38908996	38909019	3	-	26472758	Raji	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-0.7568026092806808	[232]	[31]	-5	hSpCas9	negative selection	525252
38883318	38883341	3	+	26472758	Raji	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	0.5651254856066817	[232]	[79]	5	hSpCas9	negative selection	525253
38950112	38950135	3	+	26472758	Raji	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	-0.08057538889897453	[482]	[105]	0	hSpCas9	negative selection	525254
38894682	38894705	3	-	26472758	K562	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-2.6243367390553005	[335]	[45]	-8	hSpCas9	negative selection	716363
38909119	38909142	3	+	26472758	K562	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	1.1699405117071702	[158]	[301]	8	hSpCas9	negative selection	716364
38950293	38950316	3	+	26472758	K562	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	-0.2953917366623342	[172]	[118]	-2	hSpCas9	negative selection	716365
38950187	38950210	3	+	26472758	K562	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.14641457765733046	[806]	[753]	1	hSpCas9	negative selection	716366
38950168	38950191	3	+	26472758	K562	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	-0.9804106791158341	[394]	[168]	-5	hSpCas9	negative selection	716367
38925447	38925470	3	+	26472758	K562	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	-0.9091516609255637	[306]	[137]	-5	hSpCas9	negative selection	716368
38921167	38921190	3	+	26472758	K562	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	0.6559502834437553	[411]	[547]	5	hSpCas9	negative selection	716369
38908996	38909019	3	-	26472758	K562	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-0.3461903361958514	[383]	[254]	-2	hSpCas9	negative selection	716370
38883318	38883341	3	+	26472758	K562	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	-0.11356408222260966	[313]	[244]	-1	hSpCas9	negative selection	716371
38950112	38950135	3	+	26472758	K562	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	-0.32160220940124906	[680]	[459]	-2	hSpCas9	negative selection	716372
38908107	38908130	3	-	26627737	DLD1	viability	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	-0.17385405499431245	[354]	[97,97,98]	-2	hSpCas9	negative selection	821566
38909170	38909193	3	+	26627737	DLD1	viability	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.8742654435833975	[325]	[194,276,104]	8	hSpCas9	negative selection	821567
38921143	38921166	3	+	26627737	DLD1	viability	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	0.35568792481824296	[368]	[161,189,99]	3	hSpCas9	negative selection	821568
38925445	38925468	3	+	26627737	DLD1	viability	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	0.3375595104624701	[743]	[326,281,274]	3	hSpCas9	negative selection	821569
38946850	38946873	3	+	26627737	DLD1	viability	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	0.2515846626060043	[757]	[168,408,274]	2	hSpCas9	negative selection	821570
38950257	38950280	3	-	26627737	DLD1	viability	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.5861846267005417	[583]	[177,393,257]	6	hSpCas9	negative selection	821571
38908107	38908130	3	-	26627737	GBM cells	viability after 5 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.6063603821318367	[157]	[131,125]	8	hSpCas9	negative selection	903881
38909170	38909193	3	+	26627737	GBM cells	viability after 5 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.05976788591300136	[194]	[81,135]	0	hSpCas9	negative selection	903882
38921143	38921166	3	+	26627737	GBM cells	viability after 5 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-0.3142205785896661	[232]	[111,88]	-5	hSpCas9	negative selection	903883
38925445	38925468	3	+	26627737	GBM cells	viability after 5 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-0.23012807011605313	[373]	[162,178]	-4	hSpCas9	negative selection	903884
38946850	38946873	3	+	26627737	GBM cells	viability after 5 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.3188619183803923	[363]	[147,164]	-5	hSpCas9	negative selection	903885
38950257	38950280	3	-	26627737	GBM cells	viability after 5 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.4486009008593114	[275]	[212,190]	6	hSpCas9	negative selection	903886
38908107	38908130	3	-	26627737	GBM cells	viability after 13 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.5202330441276122	[157]	[160,91]	6	hSpCas9	negative selection	986196
38909170	38909193	3	+	26627737	GBM cells	viability after 13 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.45512078694573815	[194]	[165,127]	6	hSpCas9	negative selection	986197
38921143	38921166	3	+	26627737	GBM cells	viability after 13 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-0.2599786800665171	[232]	[152,66]	-3	hSpCas9	negative selection	986198
38925445	38925468	3	+	26627737	GBM cells	viability after 13 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-0.6648742140941258	[373]	[111,140]	-7	hSpCas9	negative selection	986199
38946850	38946873	3	+	26627737	GBM cells	viability after 13 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.34915653551222325	[363]	[175,137]	-4	hSpCas9	negative selection	986200
38950257	38950280	3	-	26627737	GBM cells	viability after 13 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.6890187219501789	[275]	[268,218]	8	hSpCas9	negative selection	986201
38908107	38908130	3	-	26627737	GBM cells	viability after 21 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.5279315556847773	[157]	[140,107]	5	hSpCas9	negative selection	1068511
38909170	38909193	3	+	26627737	GBM cells	viability after 21 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.12534579745218982	[194]	[125,105]	1	hSpCas9	negative selection	1068512
38921143	38921166	3	+	26627737	GBM cells	viability after 21 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-0.04417775874740244	[232]	[139,106]	0	hSpCas9	negative selection	1068513
38925445	38925468	3	+	26627737	GBM cells	viability after 21 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-1.1844582339760228	[373]	[79,97]	-7	hSpCas9	negative selection	1068514
38946850	38946873	3	+	26627737	GBM cells	viability after 21 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	0.22279915881929724	[363]	[235,225]	2	hSpCas9	negative selection	1068515
38950257	38950280	3	-	26627737	GBM cells	viability after 21 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.33412088613357843	[275]	[211,167]	3	hSpCas9	negative selection	1068516
38908107	38908130	3	-	26627737	RPE1	viability after 9 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.7075901659185406	[576]	[201,414]	5	hSpCas9	negative selection	1150826
38909170	38909193	3	+	26627737	RPE1	viability after 9 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	1.236547663979345	[246]	[224,126]	7	hSpCas9	negative selection	1150827
38921143	38921166	3	+	26627737	RPE1	viability after 9 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-1.2887186701140398	[946]	[16,255]	-7	hSpCas9	negative selection	1150828
38925445	38925468	3	+	26627737	RPE1	viability after 9 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	0.06188402993969622	[1132]	[340,407]	0	hSpCas9	negative selection	1150829
38946850	38946873	3	+	26627737	RPE1	viability after 9 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.09437297970099856	[1458]	[319,566]	0	hSpCas9	negative selection	1150830
38950257	38950280	3	-	26627737	RPE1	viability after 9 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.12582964286108755	[1162]	[257,576]	0	hSpCas9	negative selection	1150831
38908107	38908130	3	-	26627737	RPE1	viability after 12 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.5736474305513384	[576]	[220,240]	4	hSpCas9	negative selection	1233141
38909170	38909193	3	+	26627737	RPE1	viability after 12 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	1.15161651345411	[246]	[229,59]	7	hSpCas9	negative selection	1233142
38921143	38921166	3	+	26627737	RPE1	viability after 12 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-1.009908910923988	[946]	[86,167]	-6	hSpCas9	negative selection	1233143
38925445	38925468	3	+	26627737	RPE1	viability after 12 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-0.41765405669414846	[1132]	[189,267]	-3	hSpCas9	negative selection	1233144
38946850	38946873	3	+	26627737	RPE1	viability after 12 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.48404542329389766	[1458]	[288,270]	-3	hSpCas9	negative selection	1233145
38950257	38950280	3	-	26627737	RPE1	viability after 12 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.26520001329905973	[1162]	[273,482]	1	hSpCas9	negative selection	1233146
38908107	38908130	3	-	26627737	RPE1	viability after 15 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.3661602204600499	[576]	[160,257]	2	hSpCas9	negative selection	1315456
38909170	38909193	3	+	26627737	RPE1	viability after 15 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.947656324028772	[246]	[119,148]	5	hSpCas9	negative selection	1315457
38921143	38921166	3	+	26627737	RPE1	viability after 15 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-0.9524367559024098	[946]	[85,188]	-6	hSpCas9	negative selection	1315458
38925445	38925468	3	+	26627737	RPE1	viability after 15 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	0.05530291143986832	[1132]	[190,469]	0	hSpCas9	negative selection	1315459
38946850	38946873	3	+	26627737	RPE1	viability after 15 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.42291775238080503	[1458]	[287,326]	-3	hSpCas9	negative selection	1315460
38950257	38950280	3	-	26627737	RPE1	viability after 15 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	-0.17814448122604315	[1162]	[162,413]	-1	hSpCas9	negative selection	1315461
38908107	38908130	3	-	26627737	RPE1	viability after 18 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.6823137694199072	[576]	[187,315]	4	hSpCas9	negative selection	1397771
38909170	38909193	3	+	26627737	RPE1	viability after 18 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	1.4791726548023283	[246]	[180,190]	7	hSpCas9	negative selection	1397772
38921143	38921166	3	+	26627737	RPE1	viability after 18 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-1.2294934932432773	[946]	[64,155]	-6	hSpCas9	negative selection	1397773
38925445	38925468	3	+	26627737	RPE1	viability after 18 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	0.35068067600211905	[1132]	[313,470]	2	hSpCas9	negative selection	1397774
38946850	38946873	3	+	26627737	RPE1	viability after 18 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.2986764572474573	[1458]	[366,269]	-2	hSpCas9	negative selection	1397775
38950257	38950280	3	-	26627737	RPE1	viability after 18 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.6169632847242476	[1162]	[301,672]	4	hSpCas9	negative selection	1397776
38908107	38908130	3	-	26627737	HeLa	viability after 8 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.6153773065342976	[201]	[114,184,101]	5	hSpCas9	negative selection	1480086
38909170	38909193	3	+	26627737	HeLa	viability after 8 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.4549054865939006	[253]	[187,144,130]	4	hSpCas9	negative selection	1480087
38921143	38921166	3	+	26627737	HeLa	viability after 8 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	0.1897007724331431	[234]	[178,58,124]	1	hSpCas9	negative selection	1480088
38925445	38925468	3	+	26627737	HeLa	viability after 8 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-0.3424398658506781	[640]	[316,198,168]	-3	hSpCas9	negative selection	1480089
38946850	38946873	3	+	26627737	HeLa	viability after 8 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	0.3090121507638306	[583]	[492,328,171]	3	hSpCas9	negative selection	1480090
38950257	38950280	3	-	26627737	HeLa	viability after 8 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.5771120926670347	[420]	[226,387,199]	5	hSpCas9	negative selection	1480091
38908107	38908130	3	-	26627737	HeLa	viability after 12 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.02423643442657908	[201]	[77,79,96]	0	hSpCas9	negative selection	1562401
38909170	38909193	3	+	26627737	HeLa	viability after 12 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.5520674724731577	[253]	[110,129,221]	4	hSpCas9	negative selection	1562402
38921143	38921166	3	+	26627737	HeLa	viability after 12 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	0.7848702666972366	[234]	[230,127,148]	6	hSpCas9	negative selection	1562403
38925445	38925468	3	+	26627737	HeLa	viability after 12 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	0.001822252965564708	[640]	[270,282,239]	0	hSpCas9	negative selection	1562404
38946850	38946873	3	+	26627737	HeLa	viability after 12 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.1786305562862634	[583]	[290,146,210]	-1	hSpCas9	negative selection	1562405
38950257	38950280	3	-	26627737	HeLa	viability after 12 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.7261675645935427	[420]	[318,224,326]	6	hSpCas9	negative selection	1562406
38908107	38908130	3	-	26627737	HeLa	viability after 15 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.4445798797820908	[201]	[93,165,72]	3	hSpCas9	negative selection	1644716
38909170	38909193	3	+	26627737	HeLa	viability after 15 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.21213186367776382	[253]	[27,97,146]	-2	hSpCas9	negative selection	1644717
38921143	38921166	3	+	26627737	HeLa	viability after 15 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-0.6716629063130364	[234]	[42,57,80]	-5	hSpCas9	negative selection	1644718
38925445	38925468	3	+	26627737	HeLa	viability after 15 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-1.6101160719957734	[640]	[69,120,63]	-8	hSpCas9	negative selection	1644719
38946850	38946873	3	+	26627737	HeLa	viability after 15 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	0.06822678755492517	[583]	[138,290,324]	0	hSpCas9	negative selection	1644720
38950257	38950280	3	-	26627737	HeLa	viability after 15 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.4840083218844368	[420]	[103,411,201]	4	hSpCas9	negative selection	1644721
38908107	38908130	3	-	26627737	HeLa	viability after 18 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.4081188349997906	[201]	[57,136,72]	3	hSpCas9	negative selection	1727031
38909170	38909193	3	+	26627737	HeLa	viability after 18 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.15914513080208137	[253]	[22,83,146]	-1	hSpCas9	negative selection	1727032
38921143	38921166	3	+	26627737	HeLa	viability after 18 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-0.5955600730605386	[234]	[35,46,80]	-5	hSpCas9	negative selection	1727033
38925445	38925468	3	+	26627737	HeLa	viability after 18 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-1.6094273824655536	[640]	[47,98,63]	-8	hSpCas9	negative selection	1727034
38946850	38946873	3	+	26627737	HeLa	viability after 18 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	0.07940456899563086	[583]	[88,250,324]	0	hSpCas9	negative selection	1727035
38950257	38950280	3	-	26627737	HeLa	viability after 18 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.46939905005780563	[420]	[73,329,201]	4	hSpCas9	negative selection	1727036
38908107	38908130	3	-	26627737	HCT116	viability after 6 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	-2.3424771376892206	[247]	[17,1]	-8	hSpCas9	negative selection	1809346
38909170	38909193	3	+	26627737	HCT116	viability after 6 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-2.4355718989436848	[736]	[52,3]	-8	hSpCas9	negative selection	1809347
38921143	38921166	3	+	26627737	HCT116	viability after 6 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-0.7885555881178563	[663]	[140,15]	-4	hSpCas9	negative selection	1809348
38925445	38925468	3	+	26627737	HCT116	viability after 6 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-0.3404576713077624	[1065]	[268,56]	-2	hSpCas9	negative selection	1809349
38946850	38946873	3	+	26627737	HCT116	viability after 6 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	0.643660939355825	[691]	[158,175]	3	hSpCas9	negative selection	1809350
38950257	38950280	3	-	26627737	HCT116	viability after 6 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	-1.5616967100312886	[599]	[49,21]	-7	hSpCas9	negative selection	1809351
38908107	38908130	3	-	26627737	HCT116	viability after 8 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.25201824461334	[174]	[76,165,100]	3	hSpCas9	negative selection	1891661
38909170	38909193	3	+	26627737	HCT116	viability after 8 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.03762199306135772	[230]	[177,100,113]	0	hSpCas9	negative selection	1891662
38921143	38921166	3	+	26627737	HCT116	viability after 8 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-0.4937663497907313	[269]	[133,120,62]	-5	hSpCas9	negative selection	1891663
38925445	38925468	3	+	26627737	HCT116	viability after 8 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	0.16750287178785905	[444]	[192,214,414]	2	hSpCas9	negative selection	1891664
38946850	38946873	3	+	26627737	HCT116	viability after 8 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-1.0066029395608962	[648]	[153,238,140]	-8	hSpCas9	negative selection	1891665
38950257	38950280	3	-	26627737	HCT116	viability after 8 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.20757703551846307	[295]	[195,166,201]	2	hSpCas9	negative selection	1891666
38908107	38908130	3	-	26627737	HCT116	viability after 9 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	1.2825981169465928	[247]	[307,44]	8	hSpCas9	negative selection	1973976
38909170	38909193	3	+	26627737	HCT116	viability after 9 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.17943606235415493	[736]	[414,70]	1	hSpCas9	negative selection	1973977
38921143	38921166	3	+	26627737	HCT116	viability after 9 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-0.34895952411163067	[663]	[79,185]	-2	hSpCas9	negative selection	1973978
38925445	38925468	3	+	26627737	HCT116	viability after 9 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-0.16262959266040178	[1065]	[384,150]	-1	hSpCas9	negative selection	1973979
38946850	38946873	3	+	26627737	HCT116	viability after 9 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.008197135370534098	[691]	[357,45]	0	hSpCas9	negative selection	1973980
38950257	38950280	3	-	26627737	HCT116	viability after 9 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	-2.7856486877033046	[599]	[20,24]	-9	hSpCas9	negative selection	1973981
38908107	38908130	3	-	26627737	HCT116	viability after 12 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.619350135640312	[174]	[113,172,139]	6	hSpCas9	negative selection	2056291
38909170	38909193	3	+	26627737	HCT116	viability after 12 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.4591336375317288	[230]	[124,152,225]	4	hSpCas9	negative selection	2056292
38921143	38921166	3	+	26627737	HCT116	viability after 12 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	0.23290473692834052	[269]	[189,157,149]	2	hSpCas9	negative selection	2056293
38925445	38925468	3	+	26627737	HCT116	viability after 12 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-0.45069108114826373	[444]	[154,139,218]	-5	hSpCas9	negative selection	2056294
38946850	38946873	3	+	26627737	HCT116	viability after 12 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-1.0431488184554343	[648]	[164,141,188]	-8	hSpCas9	negative selection	2056295
38950257	38950280	3	-	26627737	HCT116	viability after 12 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.3161963221415698	[295]	[181,232,167]	3	hSpCas9	negative selection	2056296
38908107	38908130	3	-	26627737	HCT116	viability after 15 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.8438582752402918	[174]	[234,148,163]	7	hSpCas9	negative selection	2138606
38909170	38909193	3	+	26627737	HCT116	viability after 15 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.5689532262184146	[230]	[112,55,101]	-5	hSpCas9	negative selection	2138607
38921143	38921166	3	+	26627737	HCT116	viability after 15 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	0.011777230591568488	[269]	[266,103,111]	0	hSpCas9	negative selection	2138608
38925445	38925468	3	+	26627737	HCT116	viability after 15 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-0.5926848917099895	[444]	[126,187,187]	-6	hSpCas9	negative selection	2138609
38946850	38946873	3	+	26627737	HCT116	viability after 15 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.5420432643219374	[648]	[329,277,169]	-5	hSpCas9	negative selection	2138610
38950257	38950280	3	-	26627737	HCT116	viability after 15 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.14362685782499215	[295]	[244,193,131]	1	hSpCas9	negative selection	2138611
38908107	38908130	3	-	26627737	HCT116	viability after 18 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.8890842809995474	[174]	[132,106,236]	7	hSpCas9	negative selection	2220921
38909170	38909193	3	+	26627737	HCT116	viability after 18 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.8241614540783855	[230]	[73,51,63]	-6	hSpCas9	negative selection	2220922
38921143	38921166	3	+	26627737	HCT116	viability after 18 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	0.35445717302372437	[269]	[241,115,144]	3	hSpCas9	negative selection	2220923
38925445	38925468	3	+	26627737	HCT116	viability after 18 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-0.1812012100027094	[444]	[187,200,178]	-2	hSpCas9	negative selection	2220924
38946850	38946873	3	+	26627737	HCT116	viability after 18 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.6470109991179351	[648]	[436,86,78]	-5	hSpCas9	negative selection	2220925
38950257	38950280	3	-	26627737	HCT116	viability after 18 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.3330997013131925	[295]	[139,177,224]	3	hSpCas9	negative selection	2220926
38914267	38914290	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCATTCCTGATTTGGCTCTCGG	SCN11A	ENSG00000168356	-1.4217714038602294	[83,39]	[5,2]	-7	dCas9-VP64	positive selection	2457115
38914267	38914290	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCATTCCTGATTTGGCTCTCGG	SCN11A	ENSG00000168356	1.0173012526552097	[133,79]	[38,100]	6	dCas9-VP64	positive selection	2552370
38950324	38950347	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCATCTGGAAAGATTACTGGG	SCN11A	ENSG00000168356	0.07960406072934989	[5,5]	[5,4]	1	hSpCas9	positive selection	3018954
38896946	38896969	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTATTCCGCATCCTCTGCGGGG	SCN11A	ENSG00000168356	0.06741811999856234	[5,5]	[4,4]	1	hSpCas9	positive selection	3018955
38909172	38909195	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGAGCCCAGTAGTACGCAGGG	SCN11A	ENSG00000168356	0.021721692582594154	[5,5]	[5,3]	0	hSpCas9	positive selection	3018956
38909076	38909099	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCTGCTCCTCATATGCCATGG	SCN11A	ENSG00000168356	0.3540888848411007	[3,4]	[4,4]	7	hSpCas9	positive selection	3018957
38950324	38950347	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCATCTGGAAAGATTACTGGG	SCN11A	ENSG00000168356	0.37191172278945883	[5,5]	[5,4]	6	hSpCas9	positive selection	3086812
38896946	38896969	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTATTCCGCATCCTCTGCGGGG	SCN11A	ENSG00000168356	0.2390972826759451	[5,5]	[4,4]	4	hSpCas9	positive selection	3086813
38909172	38909195	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGAGCCCAGTAGTACGCAGGG	SCN11A	ENSG00000168356	0.4919337228668284	[5,5]	[4,5]	8	hSpCas9	positive selection	3086814
38909076	38909099	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCTGCTCCTCATATGCCATGG	SCN11A	ENSG00000168356	-0.1516216726208358	[3,3]	[2,1]	-2	hSpCas9	positive selection	3086815
38946837	38946860		-	24336571	A375	resistance to PLX after 7 days	AAGCATGCCTTGTTCATTTTTGG	SCN11A	ENSG00000168356	-0.14821891706833257	[46,45]	[39,43]	-5	hSpCas9	positive selection	3142855
38945464	38945487		+	24336571	A375	resistance to PLX after 7 days	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.31570830328835675	[7,8]	[9,9]	8	hSpCas9	positive selection	3142856
38945460	38945483		-	24336571	A375	resistance to PLX after 7 days	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.2439516506604792	[22,21]	[27,24]	7	hSpCas9	positive selection	3142857
38946788	38946811		+	24336571	A375	resistance to PLX after 7 days	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.35369688659340726	[9,9]	[7,6]	-8	hSpCas9	positive selection	3142858
38946881	38946904		-	24336571	A375	resistance to PLX after 7 days	TTATGGTGTTAAACAGAAAGAGG	SCN11A	ENSG00000168356	-0.268329117564994	[4,5]	[3,3]	-7	hSpCas9	positive selection	3142859
38946837	38946860		-	24336571	A375	resistance to PLX after 14 days	AAGCATGCCTTGTTCATTTTTGG	SCN11A	ENSG00000168356	0.013165864514194547	[45,32]	[16,19]	0	hSpCas9	positive selection	3200648
38945464	38945487		+	24336571	A375	resistance to PLX after 14 days	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.5959950719329852	[8,8]	[5,4]	5	hSpCas9	positive selection	3200649
38945460	38945483		-	24336571	A375	resistance to PLX after 14 days	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.3499794698783969	[19,32]	[12,17]	3	hSpCas9	positive selection	3200650
38946788	38946811		+	24336571	A375	resistance to PLX after 14 days	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	0.3891187102757375	[10,7]	[4,5]	4	hSpCas9	positive selection	3200651
38946881	38946904		-	24336571	A375	resistance to PLX after 14 days	TTATGGTGTTAAACAGAAAGAGG	SCN11A	ENSG00000168356	-0.37706492429702276	[4,5]	[1,1]	-4	hSpCas9	positive selection	3200652
38946837	38946860		-	24336571	A375	viability after 7 days	AAGCATGCCTTGTTCATTTTTGG	SCN11A	ENSG00000168356	0.728615663820545	[28]	[46,45]	9	hSpCas9	negative selection	3258441
38945464	38945487		+	24336571	A375	viability after 7 days	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.8341780308222004	[4]	[7,8]	9	hSpCas9	negative selection	3258442
38945460	38945483		-	24336571	A375	viability after 7 days	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.9940652901881196	[11]	[22,21]	9	hSpCas9	negative selection	3258443
38946788	38946811		+	24336571	A375	viability after 7 days	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.010181570944716056	[9]	[9,9]	0	hSpCas9	negative selection	3258444
38946881	38946904		-	24336571	A375	viability after 7 days	TTATGGTGTTAAACAGAAAGAGG	SCN11A	ENSG00000168356	0.082441866763866	[4]	[4,5]	1	hSpCas9	negative selection	3258445
38946837	38946860		-	24336571	A375	viability after 14 days	AAGCATGCCTTGTTCATTTTTGG	SCN11A	ENSG00000168356	0.5060572912126631	[28]	[45,32]	6	hSpCas9	negative selection	3316234
38945464	38945487		+	24336571	A375	viability after 14 days	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.9204362276282907	[4]	[8,8]	9	hSpCas9	negative selection	3316235
38945460	38945483		-	24336571	A375	viability after 14 days	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	1.2402314009956938	[11]	[19,32]	9	hSpCas9	negative selection	3316236
38946788	38946811		+	24336571	A375	viability after 14 days	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.07114683268906358	[9]	[10,7]	-1	hSpCas9	negative selection	3316237
38946881	38946904		-	24336571	A375	viability after 14 days	TTATGGTGTTAAACAGAAAGAGG	SCN11A	ENSG00000168356	0.16179366984520804	[4]	[4,5]	2	hSpCas9	negative selection	3316238
38925489	38925512	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-1.3500041023037754	[389,389]	[0,0]	-8	hSpCas9	positive selection	3391415
38946788	38946811	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	0.23495839841738073	[129,129]	[0,0]	1	hSpCas9	positive selection	3391416
38926828	38926851	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	1.797894592808538	[43,43]	[0,0]	7	hSpCas9	positive selection	3391417
38950323	38950346	3	+	26780180	HT29	viability (Avana library 4 designs)	GCTCATCTGGAAAGATTACTGGG	SCN11A	ENSG00000168356	-0.643589078042075	[]	[]	-8	hSpCas9	negative selection	3457381
38896946	38896969	3	-	26780180	HT29	viability (Avana library 4 designs)	GGTATTCCGCATCCTCTGCGGGG	SCN11A	ENSG00000168356	-0.102811992192696	[]	[]	-2	hSpCas9	negative selection	3457382
38909171	38909194	3	+	26780180	HT29	viability (Avana library 4 designs)	GTAGAGCCCAGTAGTACGCAGGG	SCN11A	ENSG00000168356	-0.1819197400298	[]	[]	-3	hSpCas9	negative selection	3457383
38909075	38909098	3	+	26780180	HT29	viability (Avana library 4 designs)	GTTCTGCTCCTCATATGCCATGG	SCN11A	ENSG00000168356	0.0889372005068852	[]	[]	0	hSpCas9	negative selection	3457384
38909171	38909194	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGAGCCCAGTAGTACGCAGGG	SCN11A	ENSG00000168356	4.20582733016276	[]	[]	7	hSpCas9	negative selection	3556309
38909075	38909098	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCTGCTCCTCATATGCCATGG	SCN11A	ENSG00000168356	-0.403384870651017	[]	[]	0	hSpCas9	negative selection	3556310
38950323	38950346	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCATCTGGAAAGATTACTGGG	SCN11A	ENSG00000168356	0.310828377876126	[]	[]	0	hSpCas9	negative selection	3556311
38896946	38896969	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTATTCCGCATCCTCTGCGGGG	SCN11A	ENSG00000168356	5.17664402289972	[]	[]	8	hSpCas9	negative selection	3556312
38896952	38896975	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGGATGCGGAATACCACTAGG	SCN11A	ENSG00000168356	0.523123802378802	[]	[]	0	hSpCas9	negative selection	3556313
38894829	38894852	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCACAAAACAAAAAGCCCGGCGG	SCN11A	ENSG00000168356	-2.61983122470201	[]	[]	-3	hSpCas9	negative selection	3556314
38909171	38909194	3	+	26780180	A375	viability (Avana lentiGuide)	GTAGAGCCCAGTAGTACGCAGGG	SCN11A	ENSG00000168356	-0.216719316288465	[]	[]	0	hSpCas9	negative selection	3664968
38909075	38909098	3	+	26780180	A375	viability (Avana lentiGuide)	GTTCTGCTCCTCATATGCCATGG	SCN11A	ENSG00000168356	-0.696707269724648	[]	[]	-1	hSpCas9	negative selection	3664969
38950323	38950346	3	+	26780180	A375	viability (Avana lentiGuide)	GCTCATCTGGAAAGATTACTGGG	SCN11A	ENSG00000168356	-2.32992322722048	[]	[]	-4	hSpCas9	negative selection	3664970
38896946	38896969	3	-	26780180	A375	viability (Avana lentiGuide)	GGTATTCCGCATCCTCTGCGGGG	SCN11A	ENSG00000168356	0.496093804799753	[]	[]	0	hSpCas9	negative selection	3664971
38896952	38896975	3	+	26780180	A375	viability (Avana lentiGuide)	AGAGGATGCGGAATACCACTAGG	SCN11A	ENSG00000168356	-2.23774236541202	[]	[]	-4	hSpCas9	negative selection	3664972
38894829	38894852	3	+	26780180	A375	viability (Avana lentiGuide)	TCACAAAACAAAAAGCCCGGCGG	SCN11A	ENSG00000168356	-1.77470597790041	[]	[]	-3	hSpCas9	negative selection	3664973
38909171	38909194	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGAGCCCAGTAGTACGCAGGG	SCN11A	ENSG00000168356	0.12540820671609954	[6]	[7,6]	3	hSpCas9	positive selection	3773575
38909075	38909098	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCTGCTCCTCATATGCCATGG	SCN11A	ENSG00000168356	-0.216157272627788	[5]	[5,3]	-3	hSpCas9	positive selection	3773576
38950323	38950346	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCATCTGGAAAGATTACTGGG	SCN11A	ENSG00000168356	0.04592862386770824	[6]	[7,6]	1	hSpCas9	positive selection	3773577
38896946	38896969	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTATTCCGCATCCTCTGCGGGG	SCN11A	ENSG00000168356	0.2285572948259788	[6]	[7,7]	6	hSpCas9	positive selection	3773578
38896952	38896975	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGGATGCGGAATACCACTAGG	SCN11A	ENSG00000168356	0.18184673991650688	[5]	[5,5]	5	hSpCas9	positive selection	3773579
38894829	38894852	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCACAAAACAAAAAGCCCGGCGG	SCN11A	ENSG00000168356	-0.1844084760274317	[5]	[4,4]	-3	hSpCas9	positive selection	3773580
38909171	38909194	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGAGCCCAGTAGTACGCAGGG	SCN11A	ENSG00000168356	0.16429137347387707	[7]	[6,6]	4	hSpCas9	positive selection	3882182
38909075	38909098	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCTGCTCCTCATATGCCATGG	SCN11A	ENSG00000168356	0.03784804637011467	[5]	[6,3]	0	hSpCas9	positive selection	3882183
38950323	38950346	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCATCTGGAAAGATTACTGGG	SCN11A	ENSG00000168356	0.22484062752743672	[7]	[7,7]	6	hSpCas9	positive selection	3882184
38896946	38896969	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTATTCCGCATCCTCTGCGGGG	SCN11A	ENSG00000168356	0.24216555760256198	[7]	[6,7]	6	hSpCas9	positive selection	3882185
38896952	38896975	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGGATGCGGAATACCACTAGG	SCN11A	ENSG00000168356	0.25626912233654864	[5]	[6,5]	7	hSpCas9	positive selection	3882186
38894829	38894852	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCACAAAACAAAAAGCCCGGCGG	SCN11A	ENSG00000168356	0.23556624071213356	[6]	[5,6]	6	hSpCas9	positive selection	3882187
38925489	38925512	3	-	26780180	A375	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	1.69561495469328	[]	[]	9	hSpCas9	negative selection	3992208
38945464	38945487	3	+	26780180	A375	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.849756550991972	[]	[]	3	hSpCas9	negative selection	3992209
38926828	38926851	3	+	26780180	A375	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	1.17366687202972	[]	[]	6	hSpCas9	negative selection	3992210
38945460	38945483	3	-	26780180	A375	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.340842188236747	[]	[]	0	hSpCas9	negative selection	3992211
38946788	38946811	3	+	26780180	A375	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	1.22086768303502	[]	[]	6	hSpCas9	negative selection	3992212
38926799	38926822	3	+	26780180	A375	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	1.26494384992444	[]	[]	6	hSpCas9	negative selection	3992213
38925489	38925512	3	-	26780180	HT29	viability (GeCKOv2 library)	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	2.32164376411504	[]	[]	9	hSpCas9	negative selection	4100174
38945464	38945487	3	+	26780180	HT29	viability (GeCKOv2 library)	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	1.43574822955189	[]	[]	7	hSpCas9	negative selection	4100175
38926828	38926851	3	+	26780180	HT29	viability (GeCKOv2 library)	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	0.939429922862681	[]	[]	4	hSpCas9	negative selection	4100176
38945460	38945483	3	-	26780180	HT29	viability (GeCKOv2 library)	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.403455181063209	[]	[]	1	hSpCas9	negative selection	4100177
38946788	38946811	3	+	26780180	HT29	viability (GeCKOv2 library)	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	1.42745568033966	[]	[]	7	hSpCas9	negative selection	4100178
38926799	38926822	3	+	26780180	HT29	viability (GeCKOv2 library)	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.264010612325573	[]	[]	0	hSpCas9	negative selection	4100179
38946837	38946860	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGCATGCCTTGTTCATTTTTGG	SCN11A	ENSG00000168356	0.7214854404109414	[5]	[7,4]	9	hSpCas9	positive selection	4168642
38945464	38945487	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	-0.14639002736982898	[3]	[1,2]	-3	hSpCas9	positive selection	4168643
38945460	38945483	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.2070310177913693	[4]	[3,3]	5	hSpCas9	positive selection	4168644
38946788	38946811	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	0.1271827163098223	[2]	[1,2]	3	hSpCas9	positive selection	4168645
38946881	38946904	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTATGGTGTTAAACAGAAAGAGG	SCN11A	ENSG00000168356	-0.16259355322780678	[1]	[1,0]	-4	hSpCas9	positive selection	4168646
38946837	38946860	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGCATGCCTTGTTCATTTTTGG	SCN11A	ENSG00000168356	1.0891546607574611	[5]	[6,4,4,4]	7	hSpCas9	positive selection	4232664
38945464	38945487	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	1.1648070973692486	[2]	[0,4,0,3]	8	hSpCas9	positive selection	4232665
38945460	38945483	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	-0.13142943170587668	[4]	[3,1,1,0]	-2	hSpCas9	positive selection	4232666
38946788	38946811	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	0.49864492115472003	[3]	[0,3,5,0]	3	hSpCas9	positive selection	4232667
38946881	38946904	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTATGGTGTTAAACAGAAAGAGG	SCN11A	ENSG00000168356	2.086517791090452	[0]	[2,0,1,0]	9	hSpCas9	positive selection	4232668
38926799	38926822	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.24219800577836456	[3]	[3,2]	5	hSpCas9	positive selection	4296601
38945464	38945487	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.10770526418460559	[2]	[2,1]	2	hSpCas9	positive selection	4296602
38945460	38945483	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.44263136875513187	[3]	[4,3]	8	hSpCas9	positive selection	4296603
38925489	38925512	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.759411329340019	[4]	[3,0]	-9	hSpCas9	positive selection	4360855
38946788	38946811	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.46295007268676286	[2]	[2,0]	-7	hSpCas9	positive selection	4360856
38926828	38926851	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	0.4568208328403771	[1]	[1,1]	8	hSpCas9	positive selection	4360857
38894844	38894866	3	-	27760321	OCIAML3	viability	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	0.07235990161661632	[814,655]	[488,747]	0	hSpCas9	negative selection	4437175
38896957	38896979	3	+	27760321	OCIAML3	viability	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	0.6042011359300753	[362,253]	[198,575]	7	hSpCas9	negative selection	4437176
38899997	38900019	3	-	27760321	OCIAML3	viability	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	0.1770110006312875	[1185,1033]	[933,1037]	2	hSpCas9	negative selection	4437177
38909171	38909193	3	+	27760321	OCIAML3	viability	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.10079731727764141	[731,599]	[465,505]	-1	hSpCas9	negative selection	4437178
38945453	38945475	3	-	27760321	OCIAML3	viability	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	0.15584417368233883	[830,677]	[624,691]	1	hSpCas9	negative selection	4437179
38894844	38894866	3	-	27760321	OCIAML2	viability	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	0.15475722997950248	[814,655]	[561,785]	2	hSpCas9	negative selection	4520638
38896957	38896979	3	+	27760321	OCIAML2	viability	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	0.09167151454868122	[362,253]	[227,308]	1	hSpCas9	negative selection	4520639
38899997	38900019	3	-	27760321	OCIAML2	viability	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	0.36857714531853336	[1185,1033]	[983,1383]	5	hSpCas9	negative selection	4520640
38909171	38909193	3	+	27760321	OCIAML2	viability	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.15631684755308944	[731,599]	[424,554]	-2	hSpCas9	negative selection	4520641
38945453	38945475	3	-	27760321	OCIAML2	viability	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	0.2950790833649196	[830,677]	[707,793]	4	hSpCas9	negative selection	4520642
38894844	38894866	3	-	27760321	MV411	viability	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	-1.1544685533607115	[814,655]	[239,181]	-6	hSpCas9	negative selection	4604101
38896957	38896979	3	+	27760321	MV411	viability	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	-0.6969908562834326	[362,253]	[88,176]	-5	hSpCas9	negative selection	4604102
38899997	38900019	3	-	27760321	MV411	viability	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	0.2932948799310624	[1185,1033]	[801,1035]	2	hSpCas9	negative selection	4604103
38909171	38909193	3	+	27760321	MV411	viability	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.2788988960316568	[731,599]	[459,210]	-2	hSpCas9	negative selection	4604104
38945453	38945475	3	-	27760321	MV411	viability	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	0.5570657833572817	[830,677]	[787,639]	4	hSpCas9	negative selection	4604105
38894844	38894866	3	-	27760321	HL60	viability	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	0.3550887616400228	[814,655]	[471,1073]	4	hSpCas9	negative selection	4687564
38896957	38896979	3	+	27760321	HL60	viability	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	-0.0957953540223837	[362,253]	[271,191]	-1	hSpCas9	negative selection	4687565
38899997	38900019	3	-	27760321	HL60	viability	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	-0.2243630262875802	[1185,1033]	[751,797]	-3	hSpCas9	negative selection	4687566
38909171	38909193	3	+	27760321	HL60	viability	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.707662446275441	[731,599]	[281,383]	-6	hSpCas9	negative selection	4687567
38945453	38945475	3	-	27760321	HL60	viability	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	0.20897794326694363	[830,677]	[685,732]	2	hSpCas9	negative selection	4687568
38894844	38894866	3	-	27760321	HT1080	viability	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	-0.037123591449988336	[655,511]	[294,151]	0	hSpCas9	negative selection	4771027
38896957	38896979	3	+	27760321	HT1080	viability	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	1.7965108560267704	[253,197]	[443,168]	8	hSpCas9	negative selection	4771028
38899997	38900019	3	-	27760321	HT1080	viability	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	1.74845200689835	[1033,806]	[1286,1171]	8	hSpCas9	negative selection	4771029
38909171	38909193	3	+	27760321	HT1080	viability	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	1.3199031481336516	[599,467]	[584,471]	7	hSpCas9	negative selection	4771030
38945453	38945475	3	-	27760321	HT1080	viability	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	0.2818170438647253	[677,528]	[413,158]	1	hSpCas9	negative selection	4771031
38894844	38894866	3	-	27760321	HT29	viability after 7 days	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	0.3828866194434405	[655,511]	[1048,1146,756]	6	hSpCas9	negative selection	4854490
38896957	38896979	3	+	27760321	HT29	viability after 7 days	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	0.7495465042385442	[253,197]	[851,347,321]	9	hSpCas9	negative selection	4854491
38899997	38900019	3	-	27760321	HT29	viability after 7 days	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	0.08436828251066197	[1033,806]	[1526,1549,740]	1	hSpCas9	negative selection	4854492
38909171	38909193	3	+	27760321	HT29	viability after 7 days	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.08422335505955897	[599,467]	[562,501,857]	-1	hSpCas9	negative selection	4854493
38945453	38945475	3	-	27760321	HT29	viability after 7 days	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	-0.14486904962669023	[677,528]	[790,558,764]	-2	hSpCas9	negative selection	4854494
38894844	38894866	3	-	27760321	HT29	viability after 25 days	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	0.26418389071679815	[655,511]	[967,699,715]	2	hSpCas9	negative selection	4937953
38896957	38896979	3	+	27760321	HT29	viability after 25 days	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	0.9104313238210066	[253,197]	[423,587,442]	9	hSpCas9	negative selection	4937954
38899997	38900019	3	-	27760321	HT29	viability after 25 days	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	0.25669510815454455	[1033,806]	[1085,1292,1416]	2	hSpCas9	negative selection	4937955
38909171	38909193	3	+	27760321	HT29	viability after 25 days	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.2731363618672753	[599,467]	[391,471,674]	-3	hSpCas9	negative selection	4937956
38945453	38945475	3	-	27760321	HT29	viability after 25 days	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	0.006301044484583906	[677,528]	[518,746,836]	0	hSpCas9	negative selection	4937957
38894844	38894866	3	-	27760321	HT29	viability after 22 days	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	0.5600111945734801	[655,511]	[1168,845,965]	6	hSpCas9	negative selection	5021416
38896957	38896979	3	+	27760321	HT29	viability after 22 days	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	0.9508903493348793	[253,197]	[664,411,432]	9	hSpCas9	negative selection	5021417
38899997	38900019	3	-	27760321	HT29	viability after 22 days	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	0.25593147824403295	[1033,806]	[1140,1461,1211]	2	hSpCas9	negative selection	5021418
38909171	38909193	3	+	27760321	HT29	viability after 22 days	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.6882421233377194	[599,467]	[352,321,475]	-5	hSpCas9	negative selection	5021419
38945453	38945475	3	-	27760321	HT29	viability after 22 days	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	0.29116433292235044	[677,528]	[712,768,1084]	3	hSpCas9	negative selection	5021420
38894844	38894866	3	-	27760321	HT29	viability after 19 days	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	0.04660065431955496	[655,511]	[751,645,677]	0	hSpCas9	negative selection	5104879
38896957	38896979	3	+	27760321	HT29	viability after 19 days	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	0.9675942152532748	[253,197]	[704,384,448]	8	hSpCas9	negative selection	5104880
38899997	38900019	3	-	27760321	HT29	viability after 19 days	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	0.04358864792114625	[1033,806]	[1286,1022,969]	0	hSpCas9	negative selection	5104881
38909171	38909193	3	+	27760321	HT29	viability after 19 days	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.4801108982436928	[599,467]	[492,442,384]	-4	hSpCas9	negative selection	5104882
38945453	38945475	3	-	27760321	HT29	viability after 19 days	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	-0.04010402708086802	[677,528]	[716,732,571]	0	hSpCas9	negative selection	5104883
38894844	38894866	3	-	27760321	HT29	viability after 16 days	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	0.5781853712614683	[655,511]	[1348,805,810]	6	hSpCas9	negative selection	5188342
38896957	38896979	3	+	27760321	HT29	viability after 16 days	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	0.6899936353444938	[253,197]	[520,341,372]	7	hSpCas9	negative selection	5188343
38899997	38900019	3	-	27760321	HT29	viability after 16 days	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	0.42353657974658065	[1033,806]	[1508,1251,1397]	5	hSpCas9	negative selection	5188344
38909171	38909193	3	+	27760321	HT29	viability after 16 days	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.295049635609902	[599,467]	[512,377,574]	-3	hSpCas9	negative selection	5188345
38945453	38945475	3	-	27760321	HT29	viability after 16 days	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	0.10813580442568482	[677,528]	[784,708,694]	1	hSpCas9	negative selection	5188346
38894844	38894866	3	-	27760321	HT29	viability after 13 days	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	0.32792978090849256	[655,511]	[1008,900,652]	4	hSpCas9	negative selection	5271805
38896957	38896979	3	+	27760321	HT29	viability after 13 days	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	0.30952522776600805	[253,197]	[400,359,219]	4	hSpCas9	negative selection	5271806
38899997	38900019	3	-	27760321	HT29	viability after 13 days	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	0.18041373106842973	[1033,806]	[1137,1412,1086]	2	hSpCas9	negative selection	5271807
38909171	38909193	3	+	27760321	HT29	viability after 13 days	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.3218461841852315	[599,467]	[330,419,721]	-4	hSpCas9	negative selection	5271808
38945453	38945475	3	-	27760321	HT29	viability after 13 days	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	0.2756757312472712	[677,528]	[1177,862,520]	3	hSpCas9	negative selection	5271809
38894844	38894866	3	-	27760321	HT29	viability after 10 days	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	0.39336519074381104	[655,511]	[1023,767,1072]	5	hSpCas9	negative selection	5355268
38896957	38896979	3	+	27760321	HT29	viability after 10 days	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	0.7309842686535204	[253,197]	[454,336,605]	8	hSpCas9	negative selection	5355269
38899997	38900019	3	-	27760321	HT29	viability after 10 days	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	0.16115643478342534	[1033,806]	[1163,1235,1449]	2	hSpCas9	negative selection	5355270
38909171	38909193	3	+	27760321	HT29	viability after 10 days	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.24711626834916517	[599,467]	[445,449,780]	-3	hSpCas9	negative selection	5355271
38945453	38945475	3	-	27760321	HT29	viability after 10 days	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	-0.08349753333879939	[677,528]	[777,936,430]	-1	hSpCas9	negative selection	5355272
38894844	38894866	3	-	27760321	MOLM13	viability	GCACTGGATCGATTCCGCCGGG	SCN11A	ENSG00000168356	0.9911538859043073	[814,655]	[1132,553]	7	hSpCas9	negative selection	5438731
38896957	38896979	3	+	27760321	MOLM13	viability	ATGCGGAATACCACTAGGAAGG	SCN11A	ENSG00000168356	-1.3638837042287197	[362,253]	[108,30]	-7	hSpCas9	negative selection	5438732
38899997	38900019	3	-	27760321	MOLM13	viability	CCTACCACTACTTTCGCCGAGG	SCN11A	ENSG00000168356	-0.08856214621823089	[1185,1033]	[545,622]	0	hSpCas9	negative selection	5438733
38909171	38909193	3	+	27760321	MOLM13	viability	GTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	1.138824607632086	[731,599]	[817,827]	7	hSpCas9	negative selection	5438734
38945453	38945475	3	-	27760321	MOLM13	viability	ACTGCGTGTTCATGGCTACAGG	SCN11A	ENSG00000168356	-0.5339915791376086	[830,677]	[177,389]	-3	hSpCas9	negative selection	5438735
38950154	38950177	3	+	27661255	K562	viability	GGAATGTCGCCATAGAGCTTGGG	SCN11A	ENSG00000168356	0.1845752002293093	[1312,1445]	[1362,1153]	6	dCas9-KRAB	negative selection	5509625
38950289	38950312	3	+	27661255	K562	viability	GCCAGAGAGTCGGAAGTGAAGGG	SCN11A	ENSG00000168356	0.20507131901837428	[396,377]	[422,300]	7	dCas9-KRAB	negative selection	5509626
38926799	38926822	3	+	27260156	BXPC3	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.1668299254612795	[654]	[522,490,622,844]	-4	hSpCas9	negative selection	5569061
38945464	38945487	3	+	27260156	BXPC3	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.08385117947301102	[301]	[339,341,333,316]	1	hSpCas9	negative selection	5569062
38945460	38945483	3	-	27260156	BXPC3	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.4326413363576763	[757]	[939,975,1204,1186]	8	hSpCas9	negative selection	5569063
38925489	38925512	3	-	27260156	BXPC3	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.20514684795668015	[1015]	[884,914,859,1036]	-5	hSpCas9	negative selection	5633315
38946788	38946811	3	+	27260156	BXPC3	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.09669938026307467	[457]	[411,445,493,439]	-2	hSpCas9	negative selection	5633316
38926828	38926851	3	+	27260156	BXPC3	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.9510488379316937	[134]	[45,67,78,105]	-9	hSpCas9	negative selection	5633317
38926799	38926822	3	+	27260156	A673	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.004513258610540971	[654]	[1056,730,687,706]	0	hSpCas9	negative selection	5690312
38945464	38945487	3	+	27260156	A673	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.18526842196398313	[301]	[422,350,504,368]	4	hSpCas9	negative selection	5690313
38945460	38945483	3	-	27260156	A673	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.20170384081689763	[757]	[1087,1039,971,1092]	5	hSpCas9	negative selection	5690314
38925489	38925512	3	-	27260156	A673	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.21163037964821707	[1015]	[1124,922,1017,1163]	-5	hSpCas9	negative selection	5754566
38946788	38946811	3	+	27260156	A673	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.02212996063986948	[457]	[623,484,500,567]	0	hSpCas9	negative selection	5754567
38926828	38926851	3	+	27260156	A673	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.21870610436392934	[134]	[161,93,142,162]	-5	hSpCas9	negative selection	5754568
38926799	38926822	3	+	27260156	A375	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.010278574275821684	[654]	[868,759,838,588]	0	hSpCas9	negative selection	5811563
38945464	38945487	3	+	27260156	A375	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	-0.1537596174300241	[301]	[416,396,194,274]	-2	hSpCas9	negative selection	5811564
38945460	38945483	3	-	27260156	A375	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.5608265943068113	[757]	[1613,1464,1364,853]	8	hSpCas9	negative selection	5811565
38925489	38925512	3	-	27260156	A375	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.10179721642610118	[1015]	[1093,1438,851,1082]	-1	hSpCas9	negative selection	5875817
38946788	38946811	3	+	27260156	A375	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.1928717186954563	[457]	[530,591,408,367]	-3	hSpCas9	negative selection	5875818
38926828	38926851	3	+	27260156	A375	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	0.005742190006205572	[134]	[301,120,88,120]	0	hSpCas9	negative selection	5875819
38926799	38926822	3	+	27260156	COLO741	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.03785827014539772	[654]	[1023,717,725]	-1	hSpCas9	negative selection	5932814
38945464	38945487	3	+	27260156	COLO741	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.035487689013805945	[301]	[382,384,414]	0	hSpCas9	negative selection	5932815
38945460	38945483	3	-	27260156	COLO741	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.2720463470392074	[757]	[1201,1101,1201]	6	hSpCas9	negative selection	5932816
38925489	38925512	3	-	27260156	COLO741	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.26663750554348264	[1015]	[1040,1059,1126]	-5	hSpCas9	negative selection	5997068
38946788	38946811	3	+	27260156	COLO741	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.3572708152229471	[457]	[578,363,437]	-6	hSpCas9	negative selection	5997069
38926828	38926851	3	+	27260156	COLO741	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.27868022993886243	[134]	[109,190,123]	-5	hSpCas9	negative selection	5997070
38926799	38926822	3	+	27260156	CAL120	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.13769426964198062	[654]	[1522,757,509]	2	hSpCas9	negative selection	6054065
38945464	38945487	3	+	27260156	CAL120	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.08201649954739931	[301]	[609,321,294]	1	hSpCas9	negative selection	6054066
38945460	38945483	3	-	27260156	CAL120	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.3667236650992135	[757]	[1156,1304,1177]	5	hSpCas9	negative selection	6054067
38925489	38925512	3	-	27260156	CAL120	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.041266564586673216	[1015]	[1416,1192,1105]	0	hSpCas9	negative selection	6118319
38946788	38946811	3	+	27260156	CAL120	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.2378285341162389	[457]	[764,404,324]	-3	hSpCas9	negative selection	6118320
38926828	38926851	3	+	27260156	CAL120	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.32375787385358534	[134]	[161,177,67]	-5	hSpCas9	negative selection	6118321
38926799	38926822	3	+	27260156	CADOES1	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.00870765312857702	[654]	[638,559,614,607]	0	hSpCas9	negative selection	6175316
38945464	38945487	3	+	27260156	CADOES1	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.03790496247421704	[301]	[203,328,273,348]	0	hSpCas9	negative selection	6175317
38945460	38945483	3	-	27260156	CADOES1	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.3432358767803366	[757]	[869,1071,940,686]	6	hSpCas9	negative selection	6175318
38925489	38925512	3	-	27260156	CADOES1	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.06982878511690505	[1015]	[784,1017,788,1013]	-1	hSpCas9	negative selection	6239570
38946788	38946811	3	+	27260156	CADOES1	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.08720277947103189	[457]	[307,434,363,500]	-1	hSpCas9	negative selection	6239571
38926828	38926851	3	+	27260156	CADOES1	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.38639636677734424	[134]	[117,44,100,120]	-6	hSpCas9	negative selection	6239572
38926799	38926822	3	+	27260156	EWS502	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.014608415665588292	[654]	[491,641,672,983]	0	hSpCas9	negative selection	6296567
38945464	38945487	3	+	27260156	EWS502	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.31839943190919556	[301]	[379,461,463,279]	5	hSpCas9	negative selection	6296568
38945460	38945483	3	-	27260156	EWS502	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.5169565541644837	[757]	[961,1161,1289,1204]	8	hSpCas9	negative selection	6296569
38925489	38925512	3	-	27260156	EWS502	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.3295664248756076	[1015]	[826,713,794,1112]	-5	hSpCas9	negative selection	6360821
38946788	38946811	3	+	27260156	EWS502	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.0881438895844465	[457]	[323,335,706,482]	-1	hSpCas9	negative selection	6360822
38926828	38926851	3	+	27260156	EWS502	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.19370211458103892	[134]	[106,237,86,59]	-3	hSpCas9	negative selection	6360823
38926799	38926822	3	+	27260156	EW8	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.1416688151326979	[654]	[686,365,334,581]	-3	hSpCas9	negative selection	6417818
38945464	38945487	3	+	27260156	EW8	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.030822439370087773	[301]	[276,192,189,351]	0	hSpCas9	negative selection	6417819
38945460	38945483	3	-	27260156	EW8	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.13669734822129542	[757]	[888,684,534,637]	2	hSpCas9	negative selection	6417820
38925489	38925512	3	-	27260156	EW8	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	0.000820389586055903	[1015]	[810,907,572,1041]	0	hSpCas9	negative selection	6482072
38946788	38946811	3	+	27260156	EW8	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	0.22502845527372808	[457]	[577,311,495,352]	4	hSpCas9	negative selection	6482073
38926828	38926851	3	+	27260156	EW8	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.5758803689026213	[134]	[78,41,89,79]	-8	hSpCas9	negative selection	6482074
38926799	38926822	3	+	27260156	CORL105	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.1059870239073164	[654]	[735,695,850,589]	-2	hSpCas9	negative selection	6539069
38945464	38945487	3	+	27260156	CORL105	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.361462903246578	[301]	[493,374,538,424]	6	hSpCas9	negative selection	6539070
38945460	38945483	3	-	27260156	CORL105	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.6348536715134959	[757]	[1490,1224,1578,1254]	9	hSpCas9	negative selection	6539071
38925489	38925512	3	-	27260156	CORL105	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.1676761015515702	[1015]	[1024,1171,1063,971]	-3	hSpCas9	negative selection	6603323
38946788	38946811	3	+	27260156	CORL105	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	0.26409973950407994	[457]	[631,582,813,573]	5	hSpCas9	negative selection	6603324
38926828	38926851	3	+	27260156	CORL105	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.28201392446086015	[134]	[99,181,142,94]	-5	hSpCas9	negative selection	6603325
38926799	38926822	3	+	27260156	HS294T	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.11060953648110061	[654]	[261,172,265,420]	1	hSpCas9	negative selection	6660320
38945464	38945487	3	+	27260156	HS294T	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.5219291488897744	[301]	[183,207,107,166]	7	hSpCas9	negative selection	6660321
38945460	38945483	3	-	27260156	HS294T	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.6453904643316056	[757]	[374,498,420,560]	8	hSpCas9	negative selection	6660322
38925489	38925512	3	-	27260156	HS294T	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	0.2368493768507134	[1015]	[515,558,366,386]	3	hSpCas9	negative selection	6724574
38946788	38946811	3	+	27260156	HS294T	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.8015532865610823	[457]	[86,102,112,104]	-8	hSpCas9	negative selection	6724575
38926828	38926851	3	+	27260156	HS294T	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.5562163425119591	[134]	[16,47,38,39]	-7	hSpCas9	negative selection	6724576
38926799	38926822	3	+	27260156	HCC44	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.04609876844537747	[654]	[905,641,601,721]	0	hSpCas9	negative selection	6781571
38945464	38945487	3	+	27260156	HCC44	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.3193472584635562	[301]	[461,188,582,527]	5	hSpCas9	negative selection	6781572
38945460	38945483	3	-	27260156	HCC44	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.33261349735601986	[757]	[1222,750,1446,1013]	5	hSpCas9	negative selection	6781573
38925489	38925512	3	-	27260156	HCC44	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.36852526730376234	[1015]	[838,678,1234,884]	-5	hSpCas9	negative selection	6845825
38946788	38946811	3	+	27260156	HCC44	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.30815069558119723	[457]	[414,288,626,393]	-5	hSpCas9	negative selection	6845826
38926828	38926851	3	+	27260156	HCC44	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.6316601106866553	[134]	[67,101,151,77]	-7	hSpCas9	negative selection	6845827
38926799	38926822	3	+	27260156	G402	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.33351730115188705	[654]	[907,1531,536,1060]	4	hSpCas9	negative selection	6902822
38945464	38945487	3	+	27260156	G402	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.8283404808710372	[301]	[823,716,597,510]	8	hSpCas9	negative selection	6902823
38945460	38945483	3	-	27260156	G402	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.5966730707934965	[757]	[1538,1534,1113,1427]	7	hSpCas9	negative selection	6902824
38925489	38925512	3	-	27260156	G402	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	0.02540133659558519	[1015]	[1370,1767,934,1024]	0	hSpCas9	negative selection	6967076
38946788	38946811	3	+	27260156	G402	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.23055547052190267	[457]	[471,416,526,482]	-3	hSpCas9	negative selection	6967077
38926828	38926851	3	+	27260156	G402	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	0.1632293046511093	[134]	[95,289,170,173]	2	hSpCas9	negative selection	6967078
38926799	38926822	3	+	27260156	L33	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.07029127580127892	[654]	[687,321,367,435]	-1	hSpCas9	negative selection	7024073
38945464	38945487	3	+	27260156	L33	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.5538609137567568	[301]	[414,156,338,436]	9	hSpCas9	negative selection	7024074
38945460	38945483	3	-	27260156	L33	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.3509116652463903	[757]	[800,434,574,1091]	7	hSpCas9	negative selection	7024075
38925489	38925512	3	-	27260156	L33	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.1440756237355374	[1015]	[924,399,581,850]	-3	hSpCas9	negative selection	7088327
38946788	38946811	3	+	27260156	L33	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.11449080984509061	[457]	[478,135,241,493]	-3	hSpCas9	negative selection	7088328
38926828	38926851	3	+	27260156	L33	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.03459865122569905	[134]	[144,45,111,91]	-1	hSpCas9	negative selection	7088329
38926799	38926822	3	+	27260156	K562	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.39619387303771336	[654]	[365,508,358,518]	-5	hSpCas9	negative selection	7145324
38945464	38945487	3	+	27260156	K562	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	-0.15283470411773248	[301]	[281,436,168,104]	-2	hSpCas9	negative selection	7145325
38945460	38945483	3	-	27260156	K562	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.4202300266803133	[757]	[745,906,1234,717]	5	hSpCas9	negative selection	7145326
38925489	38925512	3	-	27260156	K562	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.010455005479546697	[1015]	[714,937,1042,870]	0	hSpCas9	negative selection	7209578
38946788	38946811	3	+	27260156	K562	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.47023382426127724	[457]	[214,470,240,252]	-5	hSpCas9	negative selection	7209579
38926828	38926851	3	+	27260156	K562	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.2630443365346846	[134]	[173,85,41,101]	-3	hSpCas9	negative selection	7209580
38926799	38926822	3	+	27260156	HT29	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.07961839473236443	[654]	[871,995,682,825]	1	hSpCas9	negative selection	7266575
38945464	38945487	3	+	27260156	HT29	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.17804468334258505	[301]	[480,337,406,428]	3	hSpCas9	negative selection	7266576
38945460	38945483	3	-	27260156	HT29	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.23057902013740927	[757]	[1307,1258,904,899]	4	hSpCas9	negative selection	7266577
38925489	38925512	3	-	27260156	HT29	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.04162314616157148	[1015]	[1467,1386,1107,901]	-1	hSpCas9	negative selection	7330829
38946788	38946811	3	+	27260156	HT29	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.08042132800700849	[457]	[568,439,703,400]	-2	hSpCas9	negative selection	7330830
38926828	38926851	3	+	27260156	HT29	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.06890196600261622	[134]	[152,199,233,53]	-1	hSpCas9	negative selection	7330831
38926799	38926822	3	+	27260156	MHHES1	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.34631839383884677	[654]	[1163,890,1218,567]	6	hSpCas9	negative selection	7387826
38945464	38945487	3	+	27260156	MHHES1	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.327670665671784	[301]	[415,662,345,319]	6	hSpCas9	negative selection	7387827
38945460	38945483	3	-	27260156	MHHES1	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.486357877874415	[757]	[1061,1441,1408,918]	8	hSpCas9	negative selection	7387828
38925489	38925512	3	-	27260156	MHHES1	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.11160719821006859	[1015]	[1076,1166,1209,826]	-2	hSpCas9	negative selection	7452080
38946788	38946811	3	+	27260156	MHHES1	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.01573775924734557	[457]	[346,710,671,340]	0	hSpCas9	negative selection	7452081
38926828	38926851	3	+	27260156	MHHES1	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-1.002764419352559	[134]	[77,98,100,35]	-9	hSpCas9	negative selection	7452082
38926799	38926822	3	+	27260156	MEWO	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.3660658796432536	[654]	[623,487,342]	-7	hSpCas9	negative selection	7509077
38945464	38945487	3	+	27260156	MEWO	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	-0.1498285764513162	[301]	[366,195,222]	-3	hSpCas9	negative selection	7509078
38945460	38945483	3	-	27260156	MEWO	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.3063947240805387	[757]	[1081,750,837]	6	hSpCas9	negative selection	7509079
38925489	38925512	3	-	27260156	MEWO	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.3457456317585982	[1015]	[718,776,741]	-6	hSpCas9	negative selection	7573331
38946788	38946811	3	+	27260156	MEWO	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.01655600407644512	[457]	[434,404,432]	0	hSpCas9	negative selection	7573332
38926828	38926851	3	+	27260156	MEWO	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.195107633660762	[134]	[120,113,97]	-4	hSpCas9	negative selection	7573333
38926799	38926822	3	+	27260156	LNCAPCLONEFGC	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.004460285591074309	[654]	[446,563,842,567]	0	hSpCas9	negative selection	7630328
38945464	38945487	3	+	27260156	LNCAPCLONEFGC	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.06614076179030148	[301]	[277,154,506,246]	1	hSpCas9	negative selection	7630329
38945460	38945483	3	-	27260156	LNCAPCLONEFGC	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.5479867890205464	[757]	[925,1113,1029,942]	8	hSpCas9	negative selection	7630330
38925489	38925512	3	-	27260156	LNCAPCLONEFGC	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.24464902195489413	[1015]	[796,812,952,566]	-4	hSpCas9	negative selection	7694582
38946788	38946811	3	+	27260156	LNCAPCLONEFGC	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.42624515882897385	[457]	[343,230,306,356]	-6	hSpCas9	negative selection	7694583
38926828	38926851	3	+	27260156	LNCAPCLONEFGC	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	0.3252474870011093	[134]	[139,228,132,102]	5	hSpCas9	negative selection	7694584
38926799	38926822	3	+	27260156	PANC0327	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.44291934811824407	[654]	[600,443,332,345]	-6	hSpCas9	negative selection	7751579
38945464	38945487	3	+	27260156	PANC0327	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	-0.16263196445482908	[301]	[313,189,187,278]	-2	hSpCas9	negative selection	7751580
38945460	38945483	3	-	27260156	PANC0327	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.163243483706641	[757]	[729,524,1092,695]	2	hSpCas9	negative selection	7751581
38925489	38925512	3	-	27260156	PANC0327	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	0.3970412957253906	[1015]	[1253,1199,1040,1261]	6	hSpCas9	negative selection	7815833
38946788	38946811	3	+	27260156	PANC0327	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	0.36411440913509835	[457]	[350,252,987,523]	5	hSpCas9	negative selection	7815834
38926828	38926851	3	+	27260156	PANC0327	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.871098003996843	[134]	[64,35,70,93]	-8	hSpCas9	negative selection	7815835
38926799	38926822	3	+	27260156	NCIH2009	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.023168325411702273	[654]	[773,1017,880]	0	hSpCas9	negative selection	7872830
38945464	38945487	3	+	27260156	NCIH2009	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.6322104341436462	[301]	[611,848,487]	8	hSpCas9	negative selection	7872831
38945460	38945483	3	-	27260156	NCIH2009	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.6936140482486935	[757]	[2066,1523,1617]	8	hSpCas9	negative selection	7872832
38925489	38925512	3	-	27260156	NCIH2009	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	0.02185770647490215	[1015]	[1551,1275,1517]	0	hSpCas9	negative selection	7937084
38946788	38946811	3	+	27260156	NCIH2009	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.09867313875732805	[457]	[817,560,456]	-1	hSpCas9	negative selection	7937085
38926828	38926851	3	+	27260156	NCIH2009	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.37360946804430895	[134]	[112,148,167]	-5	hSpCas9	negative selection	7937086
38926799	38926822	3	+	27260156	NCIH1373	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.26452687585594037	[654]	[728,765,480,120]	-3	hSpCas9	negative selection	7994081
38945464	38945487	3	+	27260156	NCIH1373	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.47858680475842397	[301]	[521,465,275,168]	5	hSpCas9	negative selection	7994082
38945460	38945483	3	-	27260156	NCIH1373	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.8195174548910252	[757]	[1670,1378,1343,432]	7	hSpCas9	negative selection	7994083
38925489	38925512	3	-	27260156	NCIH1373	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	0.3493613310303938	[1015]	[2276,1040,782,501]	3	hSpCas9	negative selection	8058335
38946788	38946811	3	+	27260156	NCIH1373	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.6196513511368109	[457]	[227,239,377,128]	-6	hSpCas9	negative selection	8058336
38926828	38926851	3	+	27260156	NCIH1373	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.38401578970726225	[134]	[256,50,154,5]	-4	hSpCas9	negative selection	8058337
38926799	38926822	3	+	27260156	PATU8902	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.11653072551860894	[654]	[430,758,817,1432]	-1	hSpCas9	negative selection	8115332
38945464	38945487	3	+	27260156	PATU8902	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.42825062282102394	[301]	[601,500,314,951]	4	hSpCas9	negative selection	8115333
38945460	38945483	3	-	27260156	PATU8902	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.8841647213859564	[757]	[2399,2269,1651,1470]	8	hSpCas9	negative selection	8115334
38925489	38925512	3	-	27260156	PATU8902	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	0.08426893056877871	[1015]	[2159,1719,831,1433]	0	hSpCas9	negative selection	8179586
38946788	38946811	3	+	27260156	PATU8902	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.14677315480366987	[457]	[461,719,588,520]	-1	hSpCas9	negative selection	8179587
38926828	38926851	3	+	27260156	PATU8902	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.59043475201187	[134]	[129,151,89,136]	-5	hSpCas9	negative selection	8179588
38926799	38926822	3	+	27260156	PANC1	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.23611294139920957	[654]	[752,812,580,540]	4	hSpCas9	negative selection	8236583
38945464	38945487	3	+	27260156	PANC1	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.266757399154162	[301]	[314,336,231,355]	4	hSpCas9	negative selection	8236584
38945460	38945483	3	-	27260156	PANC1	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.6030606114243785	[757]	[1132,1426,832,682]	8	hSpCas9	negative selection	8236585
38925489	38925512	3	-	27260156	PANC1	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.14869625555487798	[1015]	[655,1049,667,812]	-2	hSpCas9	negative selection	8300837
38946788	38946811	3	+	27260156	PANC1	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.22791709962351708	[457]	[325,442,244,343]	-4	hSpCas9	negative selection	8300838
38926828	38926851	3	+	27260156	PANC1	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.11273501212152737	[134]	[126,168,102,49]	-2	hSpCas9	negative selection	8300839
38926799	38926822	3	+	27260156	PANC0813	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.05618673205943647	[654]	[975,693,889,662]	0	hSpCas9	negative selection	8357834
38945464	38945487	3	+	27260156	PANC0813	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.3653723291695639	[301]	[482,331,589,426]	6	hSpCas9	negative selection	8357835
38945460	38945483	3	-	27260156	PANC0813	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.553522954224058	[757]	[1298,1326,1151,1437]	8	hSpCas9	negative selection	8357836
38925489	38925512	3	-	27260156	PANC0813	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	0.04179943703275746	[1015]	[1150,1143,1164,1432]	0	hSpCas9	negative selection	8422088
38946788	38946811	3	+	27260156	PANC0813	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.4369668255321353	[457]	[298,395,379,498]	-6	hSpCas9	negative selection	8422089
38926828	38926851	3	+	27260156	PANC0813	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.2741835612748391	[134]	[192,114,144,79]	-4	hSpCas9	negative selection	8422090
38926799	38926822	3	+	27260156	RDES	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.20782785903036038	[654]	[597,941,1052,929]	3	hSpCas9	negative selection	8479085
38945464	38945487	3	+	27260156	RDES	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.1342836917355439	[301]	[371,410,374,346]	2	hSpCas9	negative selection	8479086
38945460	38945483	3	-	27260156	RDES	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.5162863485185288	[757]	[1194,1022,1366,1425]	8	hSpCas9	negative selection	8479087
38925489	38925512	3	-	27260156	RDES	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.06232652311528808	[1015]	[962,973,1184,1414]	-1	hSpCas9	negative selection	8543339
38946788	38946811	3	+	27260156	RDES	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.311747500702834	[457]	[276,362,531,579]	-5	hSpCas9	negative selection	8543340
38926828	38926851	3	+	27260156	RDES	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.43282179588091396	[134]	[88,88,145,146]	-6	hSpCas9	negative selection	8543341
38926799	38926822	3	+	27260156	PC3	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.15359120367394707	[654]	[421,500,979,611]	-3	hSpCas9	negative selection	8600336
38945464	38945487	3	+	27260156	PC3	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	-0.05050600500797553	[301]	[171,216,605,321]	-1	hSpCas9	negative selection	8600337
38945460	38945483	3	-	27260156	PC3	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.21743807487674716	[757]	[606,775,1647,811]	5	hSpCas9	negative selection	8600338
38925489	38925512	3	-	27260156	PC3	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.2420375880732324	[1015]	[557,872,1257,938]	-5	hSpCas9	negative selection	8664590
38946788	38946811	3	+	27260156	PC3	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.2149999103759076	[457]	[273,529,549,275]	-5	hSpCas9	negative selection	8664591
38926828	38926851	3	+	27260156	PC3	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.8974094463323101	[134]	[61,61,117,59]	-9	hSpCas9	negative selection	8664592
38926799	38926822	3	+	27260156	PATU8988T	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.024238806738998142	[654]	[708,413,901,513]	0	hSpCas9	negative selection	8721587
38945464	38945487	3	+	27260156	PATU8988T	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.6239388717178388	[301]	[466,519,442,368]	8	hSpCas9	negative selection	8721588
38945460	38945483	3	-	27260156	PATU8988T	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	-0.11527423883480004	[757]	[612,556,758,770]	-2	hSpCas9	negative selection	8721589
38925489	38925512	3	-	27260156	PATU8988T	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.06793080711948218	[1015]	[1105,875,785,977]	-1	hSpCas9	negative selection	8785841
38946788	38946811	3	+	27260156	PATU8988T	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	0.2329159661349929	[457]	[554,515,404,612]	4	hSpCas9	negative selection	8785842
38926828	38926851	3	+	27260156	PATU8988T	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	0.025920698706629386	[134]	[110,140,105,177]	0	hSpCas9	negative selection	8785843
38926799	38926822	3	+	27260156	T47D	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.04618461877923874	[654]	[790,724,765,877]	1	hSpCas9	negative selection	8842838
38945464	38945487	3	+	27260156	T47D	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.20583619330591402	[301]	[387,388,355,494]	4	hSpCas9	negative selection	8842839
38945460	38945483	3	-	27260156	T47D	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.32697841706716	[757]	[1115,1073,1072,1172]	7	hSpCas9	negative selection	8842840
38925489	38925512	3	-	27260156	T47D	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.16282173911310427	[1015]	[1140,1016,963,1113]	-4	hSpCas9	negative selection	8907092
38946788	38946811	3	+	27260156	T47D	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.29550358020305906	[457]	[416,380,412,535]	-6	hSpCas9	negative selection	8907093
38926828	38926851	3	+	27260156	T47D	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.1807572681016263	[134]	[150,175,118,104]	-4	hSpCas9	negative selection	8907094
38926799	38926822	3	+	27260156	SU8686	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.11550768653795301	[654]	[554,642,547,653]	-2	hSpCas9	negative selection	8964089
38945464	38945487	3	+	27260156	SU8686	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.27575338102692204	[301]	[382,324,268,490]	5	hSpCas9	negative selection	8964090
38945460	38945483	3	-	27260156	SU8686	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.4461102047035327	[757]	[940,776,1047,1429]	7	hSpCas9	negative selection	8964091
38925489	38925512	3	-	27260156	SU8686	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	0.024425720583094446	[1015]	[1007,841,1136,1152]	0	hSpCas9	negative selection	9028343
38946788	38946811	3	+	27260156	SU8686	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.633835734448561	[457]	[208,247,324,423]	-7	hSpCas9	negative selection	9028344
38926828	38926851	3	+	27260156	SU8686	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.44854304591221195	[134]	[95,100,79,116]	-6	hSpCas9	negative selection	9028345
38926799	38926822	3	+	27260156	SKES1	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.06583936649572097	[654]	[536,768,634,561]	-1	hSpCas9	negative selection	9085340
38945464	38945487	3	+	27260156	SKES1	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	-0.025006441312092842	[301]	[314,360,286,235]	0	hSpCas9	negative selection	9085341
38945460	38945483	3	-	27260156	SKES1	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.25347257225137587	[757]	[996,908,914,800]	5	hSpCas9	negative selection	9085342
38925489	38925512	3	-	27260156	SKES1	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.22301343839724408	[1015]	[1011,939,1025,550]	-5	hSpCas9	negative selection	9149594
38946788	38946811	3	+	27260156	SKES1	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.20336806170240807	[457]	[414,324,498,342]	-4	hSpCas9	negative selection	9149595
38926828	38926851	3	+	27260156	SKES1	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.08567949867602964	[134]	[38,153,221,85]	-2	hSpCas9	negative selection	9149596
38926799	38926822	3	+	27260156	TOV112D	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.1733986586700279	[654]	[453,762,568,573]	-3	hSpCas9	negative selection	9206591
38945464	38945487	3	+	27260156	TOV112D	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.2471636397093509	[301]	[400,551,340,196]	5	hSpCas9	negative selection	9206592
38945460	38945483	3	-	27260156	TOV112D	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.2324496269033245	[757]	[1010,798,840,901]	4	hSpCas9	negative selection	9206593
38925489	38925512	3	-	27260156	TOV112D	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.37532615694989113	[1015]	[842,754,704,829]	-6	hSpCas9	negative selection	9270845
38946788	38946811	3	+	27260156	TOV112D	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.37624979537844927	[457]	[316,453,319,343]	-6	hSpCas9	negative selection	9270846
38926828	38926851	3	+	27260156	TOV112D	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	-0.1556992771569734	[134]	[116,349,17,57]	-3	hSpCas9	negative selection	9270847
38926799	38926822	3	+	27260156	TC71	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	-0.0851520511537115	[654]	[690,685,584,688]	-2	hSpCas9	negative selection	9327842
38945464	38945487	3	+	27260156	TC71	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.02727848231904406	[301]	[328,359,306,323]	0	hSpCas9	negative selection	9327843
38945460	38945483	3	-	27260156	TC71	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.1737280813849088	[757]	[824,940,881,1027]	4	hSpCas9	negative selection	9327844
38925489	38925512	3	-	27260156	TC71	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.3371858324347664	[1015]	[762,900,808,986]	-7	hSpCas9	negative selection	9392096
38946788	38946811	3	+	27260156	TC71	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.14238760065273892	[457]	[530,471,411,357]	-4	hSpCas9	negative selection	9392097
38926828	38926851	3	+	27260156	TC71	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	0.07124852001496018	[134]	[201,110,95,202]	1	hSpCas9	negative selection	9392098
38926799	38926822	3	+	27260156	TC32	viability	TTACGCTATTCCAATGACAATGG	SCN11A	ENSG00000168356	0.13656233650306415	[654]	[584,601,828,716]	2	hSpCas9	negative selection	9449093
38945464	38945487	3	+	27260156	TC32	viability	GAACACGCAGTTGATGATAACGG	SCN11A	ENSG00000168356	0.20654440582408434	[301]	[273,391,276,316]	4	hSpCas9	negative selection	9449094
38945460	38945483	3	-	27260156	TC32	viability	TATCATCAACTGCGTGTTCATGG	SCN11A	ENSG00000168356	0.5780642190868713	[757]	[1028,812,1349,1150]	8	hSpCas9	negative selection	9449095
38925489	38925512	3	-	27260156	TC32	viability	AGGATTGTGTCATATATTCCAGG	SCN11A	ENSG00000168356	-0.19260435209866633	[1015]	[879,573,1054,918]	-3	hSpCas9	negative selection	9513347
38946788	38946811	3	+	27260156	TC32	viability	TGAATGGACTGAGACTCTAATGG	SCN11A	ENSG00000168356	-0.11203302296609782	[457]	[275,302,528,544]	-2	hSpCas9	negative selection	9513348
38926828	38926851	3	+	27260156	TC32	viability	GCCAGTTCCATGGATCTCGAAGG	SCN11A	ENSG00000168356	0.10639480311154981	[134]	[105,131,150,157]	2	hSpCas9	negative selection	9513349
38908107	38908130	3	-	27869803	HPAFII	viability after 27 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.3938606069921333	[131]	[28,142,NaN]	3	hSpCas9	negative selection	9584637
38909170	38909193	3	+	27869803	HPAFII	viability after 27 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.26154875796376065	[164]	[19,115,NaN]	-2	hSpCas9	negative selection	9584638
38921143	38921166	3	+	27869803	HPAFII	viability after 27 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	0.8209772407377667	[193]	[285,91,NaN]	6	hSpCas9	negative selection	9584639
38925445	38925468	3	+	27869803	HPAFII	viability after 27 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	0.23857531329100512	[406]	[204,291,NaN]	2	hSpCas9	negative selection	9584640
38946850	38946873	3	+	27869803	HPAFII	viability after 27 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.7206609850736608	[321]	[153,59,NaN]	-5	hSpCas9	negative selection	9584641
38950257	38950280	3	-	27869803	HPAFII	viability after 27 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.7707116057588375	[209]	[201,176,NaN]	6	hSpCas9	negative selection	9584642
38908107	38908130	3	-	27869803	HPAFII	viability after 15 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.6090186612121113	[131]	[298,164,NaN]	7	hSpCas9	negative selection	9667086
38909170	38909193	3	+	27869803	HPAFII	viability after 15 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.07030050877055372	[164]	[208,171,NaN]	0	hSpCas9	negative selection	9667087
38921143	38921166	3	+	27869803	HPAFII	viability after 15 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	0.14255568893898754	[193]	[424,108,NaN]	1	hSpCas9	negative selection	9667088
38925445	38925468	3	+	27869803	HPAFII	viability after 15 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	-0.1407310963627768	[406]	[516,321,NaN]	-2	hSpCas9	negative selection	9667089
38946850	38946873	3	+	27869803	HPAFII	viability after 15 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.42887986173453596	[321]	[454,133,NaN]	-5	hSpCas9	negative selection	9667090
38950257	38950280	3	-	27869803	HPAFII	viability after 15 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.38699059408647973	[209]	[267,311,NaN]	4	hSpCas9	negative selection	9667091
38908107	38908130	3	-	27869803	ASPC1	viability after 36 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.5950757257478959	[427]	[225,187,252]	6	hSpCas9	negative selection	9749535
38909170	38909193	3	+	27869803	ASPC1	viability after 36 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	1.5291085188669165	[374]	[277,398,426]	9	hSpCas9	negative selection	9749536
38921143	38921166	3	+	27869803	ASPC1	viability after 36 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	-0.2063862701643232	[503]	[154,168,135]	-2	hSpCas9	negative selection	9749537
38925445	38925468	3	+	27869803	ASPC1	viability after 36 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	0.8203061104586106	[914]	[433,1042,268]	7	hSpCas9	negative selection	9749538
38946850	38946873	3	+	27869803	ASPC1	viability after 36 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.08336299659705065	[877]	[410,375,131]	-1	hSpCas9	negative selection	9749539
38950257	38950280	3	-	27869803	ASPC1	viability after 36 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	-0.2593195906203459	[701]	[349,129,159]	-3	hSpCas9	negative selection	9749540
38908107	38908130	3	-	27869803	PATU8988S	viability after 35 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.21198516565961129	[510]	[185,290,NaN]	2	hSpCas9	negative selection	9831984
38909170	38909193	3	+	27869803	PATU8988S	viability after 35 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	1.1491578941788976	[327]	[284,300,NaN]	9	hSpCas9	negative selection	9831985
38921143	38921166	3	+	27869803	PATU8988S	viability after 35 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	0.13242672000847078	[409]	[181,179,NaN]	1	hSpCas9	negative selection	9831986
38925445	38925468	3	+	27869803	PATU8988S	viability after 35 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	0.7961597701626835	[567]	[501,291,NaN]	8	hSpCas9	negative selection	9831987
38946850	38946873	3	+	27869803	PATU8988S	viability after 35 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	0.10680479954241423	[749]	[225,424,NaN]	1	hSpCas9	negative selection	9831988
38950257	38950280	3	-	27869803	PATU8988S	viability after 35 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.00301159179633987	[525]	[119,304,NaN]	0	hSpCas9	negative selection	9831989
38908107	38908130	3	-	27869803	PATU8988S	viability after 31 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	0.05411861652271293	[510]	[145,294,NaN]	0	hSpCas9	negative selection	9914433
38909170	38909193	3	+	27869803	PATU8988S	viability after 31 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	0.9837137535314701	[327]	[255,261,NaN]	9	hSpCas9	negative selection	9914434
38921143	38921166	3	+	27869803	PATU8988S	viability after 31 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	0.18609313729207694	[409]	[152,227,NaN]	2	hSpCas9	negative selection	9914435
38925445	38925468	3	+	27869803	PATU8988S	viability after 31 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	1.1710606796595842	[567]	[487,537,NaN]	9	hSpCas9	negative selection	9914436
38946850	38946873	3	+	27869803	PATU8988S	viability after 31 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	0.16823254292688888	[749]	[167,549,NaN]	2	hSpCas9	negative selection	9914437
38950257	38950280	3	-	27869803	PATU8988S	viability after 31 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.2617481502081984	[525]	[166,358,NaN]	3	hSpCas9	negative selection	9914438
38908107	38908130	3	-	27869803	HPAFII	viability after 35 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	-1.0813193532407495	[131]	[16,47,NaN]	-6	hSpCas9	negative selection	9996882
38909170	38909193	3	+	27869803	HPAFII	viability after 35 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.747809639895109	[164]	[5,98,NaN]	-4	hSpCas9	negative selection	9996883
38921143	38921166	3	+	27869803	HPAFII	viability after 35 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	1.9507402093056703	[193]	[643,81,NaN]	9	hSpCas9	negative selection	9996884
38925445	38925468	3	+	27869803	HPAFII	viability after 35 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	0.3028084203792193	[406]	[105,420,NaN]	2	hSpCas9	negative selection	9996885
38946850	38946873	3	+	27869803	HPAFII	viability after 35 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.026258858224264325	[321]	[184,131,NaN]	0	hSpCas9	negative selection	9996886
38950257	38950280	3	-	27869803	HPAFII	viability after 35 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.7625761108711313	[209]	[193,164,NaN]	5	hSpCas9	negative selection	9996887
38908107	38908130	3	-	27869803	HPAFII	viability after 31 days	TTTGAAGGCTCTGGTTGCCATGG	SCN11A	ENSG00000168356	-0.7036813160845135	[131]	[33,57,NaN]	-4	hSpCas9	negative selection	10079331
38909170	38909193	3	+	27869803	HPAFII	viability after 31 days	AGTAGAGCCCAGTAGTACGCAGG	SCN11A	ENSG00000168356	-0.6317393117660562	[164]	[20,101,NaN]	-4	hSpCas9	negative selection	10079332
38921143	38921166	3	+	27869803	HPAFII	viability after 31 days	GAAGAGCTGCTGACCTACCAGGG	SCN11A	ENSG00000168356	0.9618648134171816	[193]	[302,112,NaN]	7	hSpCas9	negative selection	10079333
38925445	38925468	3	+	27869803	HPAFII	viability after 31 days	TGAACACACGGAAGGTACGCAGG	SCN11A	ENSG00000168356	0.5180741646044268	[406]	[239,421,NaN]	4	hSpCas9	negative selection	10079334
38946850	38946873	3	+	27869803	HPAFII	viability after 31 days	AGGCATGCTTGGCACTGAAGCGG	SCN11A	ENSG00000168356	-0.29227606163190395	[321]	[137,157,NaN]	-2	hSpCas9	negative selection	10079335
38950257	38950280	3	-	27869803	HPAFII	viability after 31 days	GAAGCGGATTGCCATCCAAAAGG	SCN11A	ENSG00000168356	0.7950827149508837	[209]	[170,240,NaN]	6	hSpCas9	negative selection	10079336
38894682	38894705	3	-	28162770	P31FUJ	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-0.8957672171368078	[151]	[95]	-6	hSpCas9	negative selection	10230608
38909119	38909142	3	+	28162770	P31FUJ	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	0.9148103349573362	[180]	[400]	9	hSpCas9	negative selection	10230609
38950293	38950316	3	+	28162770	P31FUJ	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	0.7503239770212249	[42]	[84]	8	hSpCas9	negative selection	10230610
38950187	38950210	3	+	28162770	P31FUJ	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.6232883841869078	[236]	[428]	7	hSpCas9	negative selection	10230611
38950168	38950191	3	+	28162770	P31FUJ	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	0.9287869378598694	[134]	[301]	9	hSpCas9	negative selection	10230612
38925447	38925470	3	+	28162770	P31FUJ	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	-1.352711668149575	[162]	[74]	-7	hSpCas9	negative selection	10230613
38921167	38921190	3	+	28162770	P31FUJ	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	0.6187866888036028	[311]	[562]	7	hSpCas9	negative selection	10230614
38908996	38909019	3	-	28162770	P31FUJ	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-0.2831072862624442	[320]	[309]	-3	hSpCas9	negative selection	10230615
38883318	38883341	3	+	28162770	P31FUJ	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	-0.5584727009875579	[385]	[307]	-5	hSpCas9	negative selection	10230616
38950112	38950135	3	+	28162770	P31FUJ	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	0.29550012871805476	[501]	[723]	3	hSpCas9	negative selection	10230617
38894682	38894705	3	-	28162770	TF1	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10399974
38909119	38909142	3	+	28162770	TF1	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	NaN	[NaN]	[295]	1	hSpCas9	negative selection	10399975
38950293	38950316	3	+	28162770	TF1	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10399976
38950187	38950210	3	+	28162770	TF1	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	NaN	[NaN]	[263]	1	hSpCas9	negative selection	10399977
38950168	38950191	3	+	28162770	TF1	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	NaN	[NaN]	[162]	1	hSpCas9	negative selection	10399978
38925447	38925470	3	+	28162770	TF1	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	NaN	[NaN]	[58]	1	hSpCas9	negative selection	10399979
38921167	38921190	3	+	28162770	TF1	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	NaN	[NaN]	[448]	1	hSpCas9	negative selection	10399980
38908996	38909019	3	-	28162770	TF1	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	NaN	[NaN]	[170]	1	hSpCas9	negative selection	10399981
38883318	38883341	3	+	28162770	TF1	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	NaN	[NaN]	[348]	1	hSpCas9	negative selection	10399982
38950112	38950135	3	+	28162770	TF1	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	NaN	[NaN]	[411]	1	hSpCas9	negative selection	10399983
38894682	38894705	3	-	28162770	SKM1	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-2.8220016980220057	[39]	[9]	-9	hSpCas9	negative selection	10569340
38909119	38909142	3	+	28162770	SKM1	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	1.0119883505390654	[45]	[163]	8	hSpCas9	negative selection	10569341
38950293	38950316	3	+	28162770	SKM1	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	1.0922684279521107	[12]	[48]	8	hSpCas9	negative selection	10569342
38950187	38950210	3	+	28162770	SKM1	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.10493483978827123	[80]	[153]	1	hSpCas9	negative selection	10569343
38950168	38950191	3	+	28162770	SKM1	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	0.512982549690803	[43]	[110]	5	hSpCas9	negative selection	10569344
38925447	38925470	3	+	28162770	SKM1	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	0.15782042004036406	[35]	[70]	1	hSpCas9	negative selection	10569345
38921167	38921190	3	+	28162770	SKM1	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	-0.21027228773806383	[88]	[135]	-2	hSpCas9	negative selection	10569346
38908996	38909019	3	-	28162770	SKM1	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-0.7134772412438363	[63]	[68]	-5	hSpCas9	negative selection	10569347
38883318	38883341	3	+	28162770	SKM1	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	-0.3525164147207854	[77]	[107]	-3	hSpCas9	negative selection	10569348
38950112	38950135	3	+	28162770	SKM1	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	0.5703157247567547	[71]	[188]	5	hSpCas9	negative selection	10569349
38894682	38894705	3	-	28162770	SKM1	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-2.8220016980220057	[39]	[9]	-9	hSpCas9	negative selection	10738706
38909119	38909142	3	+	28162770	SKM1	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	1.0119883505390654	[45]	[163]	8	hSpCas9	negative selection	10738707
38950293	38950316	3	+	28162770	SKM1	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	1.0922684279521107	[12]	[48]	8	hSpCas9	negative selection	10738708
38950187	38950210	3	+	28162770	SKM1	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.10493483978827123	[80]	[153]	1	hSpCas9	negative selection	10738709
38950168	38950191	3	+	28162770	SKM1	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	0.512982549690803	[43]	[110]	5	hSpCas9	negative selection	10738710
38925447	38925470	3	+	28162770	SKM1	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	0.15782042004036406	[35]	[70]	1	hSpCas9	negative selection	10738711
38921167	38921190	3	+	28162770	SKM1	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	-0.21027228773806383	[88]	[135]	-2	hSpCas9	negative selection	10738712
38908996	38909019	3	-	28162770	SKM1	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-0.7134772412438363	[63]	[68]	-5	hSpCas9	negative selection	10738713
38883318	38883341	3	+	28162770	SKM1	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	-0.3525164147207854	[77]	[107]	-3	hSpCas9	negative selection	10738714
38950112	38950135	3	+	28162770	SKM1	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	0.5703157247567547	[71]	[188]	5	hSpCas9	negative selection	10738715
38894682	38894705	3	-	28162770	PL21	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-1.8648158273514497	[158]	[18]	-8	hSpCas9	negative selection	10908072
38909119	38909142	3	+	28162770	PL21	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	0.6976392739601369	[152]	[107]	6	hSpCas9	negative selection	10908073
38950293	38950316	3	+	28162770	PL21	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	0.743281939515849	[69]	[50]	6	hSpCas9	negative selection	10908074
38950187	38950210	3	+	28162770	PL21	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.3914725549689253	[274]	[156]	3	hSpCas9	negative selection	10908075
38950168	38950191	3	+	28162770	PL21	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	-0.27075111952304104	[157]	[56]	-2	hSpCas9	negative selection	10908076
38925447	38925470	3	+	28162770	PL21	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	0.25018029698891564	[169]	[87]	2	hSpCas9	negative selection	10908077
38921167	38921190	3	+	28162770	PL21	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	0.3748181459022672	[201]	[113]	3	hSpCas9	negative selection	10908078
38908996	38909019	3	-	28162770	PL21	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	0.21769798587362477	[244]	[123]	2	hSpCas9	negative selection	10908079
38883318	38883341	3	+	28162770	PL21	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	1.0581206096168922	[223]	[202]	8	hSpCas9	negative selection	10908080
38950112	38950135	3	+	28162770	PL21	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	0.6801325556089336	[303]	[211]	6	hSpCas9	negative selection	10908081
38894682	38894705	3	-	28162770	P31FUJ	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-0.8957672171368078	[151]	[95]	-6	hSpCas9	negative selection	11077438
38909119	38909142	3	+	28162770	P31FUJ	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	0.9148103349573362	[180]	[400]	9	hSpCas9	negative selection	11077439
38950293	38950316	3	+	28162770	P31FUJ	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	0.7503239770212249	[42]	[84]	8	hSpCas9	negative selection	11077440
38950187	38950210	3	+	28162770	P31FUJ	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.6232883841869078	[236]	[428]	7	hSpCas9	negative selection	11077441
38950168	38950191	3	+	28162770	P31FUJ	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	0.9287869378598694	[134]	[301]	9	hSpCas9	negative selection	11077442
38925447	38925470	3	+	28162770	P31FUJ	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	-1.352711668149575	[162]	[74]	-7	hSpCas9	negative selection	11077443
38921167	38921190	3	+	28162770	P31FUJ	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	0.6187866888036028	[311]	[562]	7	hSpCas9	negative selection	11077444
38908996	38909019	3	-	28162770	P31FUJ	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-0.2831072862624442	[320]	[309]	-3	hSpCas9	negative selection	11077445
38883318	38883341	3	+	28162770	P31FUJ	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	-0.5584727009875579	[385]	[307]	-5	hSpCas9	negative selection	11077446
38950112	38950135	3	+	28162770	P31FUJ	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	0.29550012871805476	[501]	[723]	3	hSpCas9	negative selection	11077447
38894682	38894705	3	-	28162770	OCIAML5	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-3.0891057681648464	[65]	[13]	-9	hSpCas9	negative selection	11246804
38909119	38909142	3	+	28162770	OCIAML5	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	2.0565104013724085	[56]	[427]	9	hSpCas9	negative selection	11246805
38950293	38950316	3	+	28162770	OCIAML5	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	-0.873440221656564	[67]	[66]	-5	hSpCas9	negative selection	11246806
38950187	38950210	3	+	28162770	OCIAML5	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.6351461385737682	[172]	[484]	5	hSpCas9	negative selection	11246807
38950168	38950191	3	+	28162770	OCIAML5	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	0.6572614920203079	[123]	[352]	6	hSpCas9	negative selection	11246808
38925447	38925470	3	+	28162770	OCIAML5	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	-0.21819446966189432	[86]	[134]	-1	hSpCas9	negative selection	11246809
38921167	38921190	3	+	28162770	OCIAML5	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	0.08204549347954593	[223]	[427]	0	hSpCas9	negative selection	11246810
38908996	38909019	3	-	28162770	OCIAML5	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-0.6139068336692324	[194]	[229]	-4	hSpCas9	negative selection	11246811
38883318	38883341	3	+	28162770	OCIAML5	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	0.06011555034458582	[253]	[477]	0	hSpCas9	negative selection	11246812
38950112	38950135	3	+	28162770	OCIAML5	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	0.1417548542068786	[233]	[465]	1	hSpCas9	negative selection	11246813
38894682	38894705	3	-	28162770	EOL1	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-2.4504916597763904	[248]	[23]	-8	hSpCas9	negative selection	11416170
38909119	38909142	3	+	28162770	EOL1	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	0.3533910703744089	[207]	[139]	3	hSpCas9	negative selection	11416171
38950293	38950316	3	+	28162770	EOL1	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	1.2943043915485117	[88]	[114]	9	hSpCas9	negative selection	11416172
38950187	38950210	3	+	28162770	EOL1	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.07131248809361268	[606]	[335]	0	hSpCas9	negative selection	11416173
38950168	38950191	3	+	28162770	EOL1	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	-0.18962324834877653	[367]	[169]	-1	hSpCas9	negative selection	11416174
38925447	38925470	3	+	28162770	EOL1	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	-0.32699099542543	[249]	[104]	-2	hSpCas9	negative selection	11416175
38921167	38921190	3	+	28162770	EOL1	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	0.6074636489144862	[222]	[178]	5	hSpCas9	negative selection	11416176
38908996	38909019	3	-	28162770	EOL1	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-0.40965865309526456	[294]	[116]	-3	hSpCas9	negative selection	11416177
38883318	38883341	3	+	28162770	EOL1	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	-0.1425664242880025	[351]	[167]	-1	hSpCas9	negative selection	11416178
38950112	38950135	3	+	28162770	EOL1	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	0.2173978318398898	[430]	[263]	2	hSpCas9	negative selection	11416179
38894682	38894705	3	-	28162770	MOLM13	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-1.3394655405130254	[167]	[47]	-6	hSpCas9	negative selection	11585536
38909119	38909142	3	+	28162770	MOLM13	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	0.18464175482127637	[229]	[188]	1	hSpCas9	negative selection	11585537
38950293	38950316	3	+	28162770	MOLM13	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	0.8413477770720234	[87]	[113]	6	hSpCas9	negative selection	11585538
38950187	38950210	3	+	28162770	MOLM13	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.8211052957241038	[446]	[570]	6	hSpCas9	negative selection	11585539
38950168	38950191	3	+	28162770	MOLM13	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	-0.010994599758890972	[307]	[220]	0	hSpCas9	negative selection	11585540
38925447	38925470	3	+	28162770	MOLM13	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	0.4754626012493798	[189]	[190]	3	hSpCas9	negative selection	11585541
38921167	38921190	3	+	28162770	MOLM13	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	0.4768225063145866	[321]	[323]	3	hSpCas9	negative selection	11585542
38908996	38909019	3	-	28162770	MOLM13	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-0.12935144895501416	[294]	[194]	-1	hSpCas9	negative selection	11585543
38883318	38883341	3	+	28162770	MOLM13	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	0.9336678410159589	[432]	[597]	7	hSpCas9	negative selection	11585544
38950112	38950135	3	+	28162770	MOLM13	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	-0.4121499944145084	[518]	[281]	-2	hSpCas9	negative selection	11585545
38894682	38894705	3	-	28162770	HEL	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-1.7722986672784866	[191]	[35]	-7	hSpCas9	negative selection	11754902
38909119	38909142	3	+	28162770	HEL	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	0.6264370196712565	[177]	[175]	5	hSpCas9	negative selection	11754903
38950293	38950316	3	+	28162770	HEL	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	2.146505249873532	[66]	[189]	9	hSpCas9	negative selection	11754904
38950187	38950210	3	+	28162770	HEL	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.24064038842901125	[406]	[307]	2	hSpCas9	negative selection	11754905
38950168	38950191	3	+	28162770	HEL	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	-0.057059260583844446	[280]	[172]	0	hSpCas9	negative selection	11754906
38925447	38925470	3	+	28162770	HEL	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	-0.25273058452833624	[172]	[92]	-2	hSpCas9	negative selection	11754907
38921167	38921190	3	+	28162770	HEL	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	0.49722772964905604	[270]	[244]	4	hSpCas9	negative selection	11754908
38908996	38909019	3	-	28162770	HEL	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-0.8703307502390136	[273]	[95]	-5	hSpCas9	negative selection	11754909
38883318	38883341	3	+	28162770	HEL	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	0.5488719085361344	[253]	[237]	4	hSpCas9	negative selection	11754910
38950112	38950135	3	+	28162770	HEL	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	-0.5979389423638404	[396]	[167]	-4	hSpCas9	negative selection	11754911
38894682	38894705	3	-	28162770	MV411	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-0.9960164860815024	[160]	[67]	-6	hSpCas9	negative selection	11924268
38909119	38909142	3	+	28162770	MV411	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	2.0279508606217385	[123]	[425]	9	hSpCas9	negative selection	11924269
38950293	38950316	3	+	28162770	MV411	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	0.22359080882840776	[60]	[59]	2	hSpCas9	negative selection	11924270
38950187	38950210	3	+	28162770	MV411	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	-0.2959584572127367	[324]	[222]	-2	hSpCas9	negative selection	11924271
38950168	38950191	3	+	28162770	MV411	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	0.07751254934046292	[143]	[127]	0	hSpCas9	negative selection	11924272
38925447	38925470	3	+	28162770	MV411	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	-0.2466715194872673	[99]	[70]	-2	hSpCas9	negative selection	11924273
38921167	38921190	3	+	28162770	MV411	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	1.2018749734023317	[192]	[373]	9	hSpCas9	negative selection	11924274
38908996	38909019	3	-	28162770	MV411	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-1.6837005910724205	[224]	[58]	-8	hSpCas9	negative selection	11924275
38883318	38883341	3	+	28162770	MV411	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	0.4133157191623858	[237]	[266]	3	hSpCas9	negative selection	11924276
38950112	38950135	3	+	28162770	MV411	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	-0.37279027975757795	[351]	[228]	-3	hSpCas9	negative selection	11924277
38894682	38894705	3	-	28162770	MONOMAC1	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	0.15597892561190566	[100]	[128]	1	hSpCas9	negative selection	12093634
38909119	38909142	3	+	28162770	MONOMAC1	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	1.121785336959987	[92]	[231]	8	hSpCas9	negative selection	12093635
38950293	38950316	3	+	28162770	MONOMAC1	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	-0.05953332330961891	[39]	[43]	0	hSpCas9	negative selection	12093636
38950187	38950210	3	+	28162770	MONOMAC1	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	1.1121677402071661	[204]	[507]	8	hSpCas9	negative selection	12093637
38950168	38950191	3	+	28162770	MONOMAC1	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	-0.18646760534936646	[135]	[136]	-2	hSpCas9	negative selection	12093638
38925447	38925470	3	+	28162770	MONOMAC1	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	-0.06697630649518083	[105]	[115]	0	hSpCas9	negative selection	12093639
38921167	38921190	3	+	28162770	MONOMAC1	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	1.3645210493266586	[144]	[427]	9	hSpCas9	negative selection	12093640
38908996	38909019	3	-	28162770	MONOMAC1	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	-0.19703684705955388	[147]	[147]	-2	hSpCas9	negative selection	12093641
38883318	38883341	3	+	28162770	MONOMAC1	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	0.6926397380344478	[162]	[301]	6	hSpCas9	negative selection	12093642
38950112	38950135	3	+	28162770	MONOMAC1	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	2.3478987597900263	[200]	[1172]	9	hSpCas9	negative selection	12093643
38894682	38894705	3	-	28162770	OCIAML2	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-1.13998451325369	[32]	[82]	-6	hSpCas9	negative selection	12263000
38909119	38909142	3	+	28162770	OCIAML2	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	0.7581888652537198	[23]	[224]	7	hSpCas9	negative selection	12263001
38950293	38950316	3	+	28162770	OCIAML2	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	0.3367250968154427	[13]	[97]	3	hSpCas9	negative selection	12263002
38950187	38950210	3	+	28162770	OCIAML2	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.3140050203153594	[63]	[440]	3	hSpCas9	negative selection	12263003
38950168	38950191	3	+	28162770	OCIAML2	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	1.3831995266149435	[23]	[346]	9	hSpCas9	negative selection	12263004
38925447	38925470	3	+	28162770	OCIAML2	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	-0.777607578663552	[29]	[96]	-5	hSpCas9	negative selection	12263005
38921167	38921190	3	+	28162770	OCIAML2	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	1.1403949720651911	[31]	[390]	9	hSpCas9	negative selection	12263006
38908996	38909019	3	-	28162770	OCIAML2	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	0.6386688172486503	[26]	[232]	6	hSpCas9	negative selection	12263007
38883318	38883341	3	+	28162770	OCIAML2	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	-0.10413617792135427	[50]	[262]	-1	hSpCas9	negative selection	12263008
38950112	38950135	3	+	28162770	OCIAML2	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	-0.24491704561410188	[61]	[289]	-2	hSpCas9	negative selection	12263009
38894682	38894705	3	-	28162770	OCIAML3	viability	AAGGGGCTCAGAGACCCAGGAGG	SCN11A	ENSG00000168356	-0.7914537045303803	[42]	[74]	-5	hSpCas9	negative selection	12432366
38909119	38909142	3	+	28162770	OCIAML3	viability	TAATCAGGTAGAAGGAGCCCAGG	SCN11A	ENSG00000168356	0.03562390973072122	[52]	[163]	0	hSpCas9	negative selection	12432367
38950293	38950316	3	+	28162770	OCIAML3	viability	GAGAGTCGGAAGTGAAGGGGCGG	SCN11A	ENSG00000168356	-0.5200070588803862	[18]	[39]	-4	hSpCas9	negative selection	12432368
38950187	38950210	3	+	28162770	OCIAML3	viability	GAGGCCTTTAGGTCAAGCTGAGG	SCN11A	ENSG00000168356	0.1303579170624095	[68]	[227]	1	hSpCas9	negative selection	12432369
38950168	38950191	3	+	28162770	OCIAML3	viability	GAGCTTGGGCAACTTCCTGGAGG	SCN11A	ENSG00000168356	-0.07375082899082219	[37]	[108]	0	hSpCas9	negative selection	12432370
38925447	38925470	3	+	28162770	OCIAML3	viability	AACACACGGAAGGTACGCAGGGG	SCN11A	ENSG00000168356	-0.8055117455178749	[32]	[56]	-5	hSpCas9	negative selection	12432371
38921167	38921190	3	+	28162770	OCIAML3	viability	AAAGATGCTGAGGCAAAAGAAGG	SCN11A	ENSG00000168356	-0.16824373445226082	[66]	[179]	-1	hSpCas9	negative selection	12432372
38908996	38909019	3	-	28162770	OCIAML3	viability	GCTGTTAAAGGAGGAAAAGGAGG	SCN11A	ENSG00000168356	0.6816268022892642	[56]	[275]	6	hSpCas9	negative selection	12432373
38883318	38883341	3	+	28162770	OCIAML3	viability	AGGTTCCACCAAATGACCCAGGG	SCN11A	ENSG00000168356	0.6036381186765991	[62]	[288]	5	hSpCas9	negative selection	12432374
38950112	38950135	3	+	28162770	OCIAML3	viability	AATGGGTCCAAGTCTTCCAGAGG	SCN11A	ENSG00000168356	0.375618710632318	[95]	[375]	3	hSpCas9	negative selection	12432375