Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6334
• Symbol:SCN8A
• Description:sodium voltage-gated channel alpha subunit 8

DataSource: http://genomecrispr.dkfz.de/#!/results/SCN8A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
51721662	51721685	12	+	26472758	Jiyoye	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	0.502934364311304	[101]	[108]	4	hSpCas9	negative selection	143122
51721818	51721841	12	+	26472758	Jiyoye	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	1.275930848227621	[22]	[41]	7	hSpCas9	negative selection	143123
51769122	51769145	12	-	26472758	Jiyoye	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	-0.3553253047674702	[94]	[55]	-3	hSpCas9	negative selection	143124
51662807	51662830	12	+	26472758	Jiyoye	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.0002657631104299174	[235]	[177]	0	hSpCas9	negative selection	143125
51702856	51702879	12	-	26472758	Jiyoye	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	1.4071753815058734	[39]	[79]	8	hSpCas9	negative selection	143126
51705533	51705556	12	+	26472758	Jiyoye	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	0.5140905854223856	[51]	[55]	4	hSpCas9	negative selection	143127
51706552	51706575	12	+	26472758	Jiyoye	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-1.0160360492186706	[58]	[21]	-6	hSpCas9	negative selection	143128
51706601	51706624	12	+	26472758	Jiyoye	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	-0.8228302239404496	[189]	[80]	-5	hSpCas9	negative selection	143129
51721675	51721698	12	+	26472758	Jiyoye	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	1.0592520780855665	[41]	[65]	7	hSpCas9	negative selection	143130
51721698	51721721	12	-	26472758	Jiyoye	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	4.729103476393235	[0]	[19]	9	hSpCas9	negative selection	143131
51721662	51721685	12	+	26472758	KBM7	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	0.2731873484515012	[376,242]	[104,233]	3	hSpCas9	negative selection	334240
51721818	51721841	12	+	26472758	KBM7	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.24544538648488867	[201,76]	[110,41]	2	hSpCas9	negative selection	334241
51769122	51769145	12	-	26472758	KBM7	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	-0.05820977876334932	[388,275]	[76,211]	0	hSpCas9	negative selection	334242
51662807	51662830	12	+	26472758	KBM7	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	1.0024683541532533	[664,500]	[695,407]	9	hSpCas9	negative selection	334243
51702856	51702879	12	-	26472758	KBM7	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	0.13772547976444705	[250,264]	[115,150]	1	hSpCas9	negative selection	334244
51705533	51705556	12	+	26472758	KBM7	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	-0.5488980775534691	[177,150]	[86,21]	-5	hSpCas9	negative selection	334245
51706552	51706575	12	+	26472758	KBM7	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	0.2812257735863346	[94,92]	[64,43]	3	hSpCas9	negative selection	334246
51706601	51706624	12	+	26472758	KBM7	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	-0.06401949601001111	[363,399]	[154,189]	0	hSpCas9	negative selection	334247
51721675	51721698	12	+	26472758	KBM7	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	-0.0011920230661128725	[373,586]	[128,323]	0	hSpCas9	negative selection	334248
51721698	51721721	12	-	26472758	KBM7	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	0.5970198095939554	[19,21]	[22,7]	6	hSpCas9	negative selection	334249
51721662	51721685	12	+	26472758	Raji	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	-0.19796167531815861	[172]	[34]	-2	hSpCas9	negative selection	525358
51721818	51721841	12	+	26472758	Raji	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.07990279895149266	[52]	[12]	0	hSpCas9	negative selection	525359
51769122	51769145	12	-	26472758	Raji	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.8414894754005651	[100]	[41]	7	hSpCas9	negative selection	525360
51662807	51662830	12	+	26472758	Raji	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.5396990260842789	[248]	[83]	5	hSpCas9	negative selection	525361
51702856	51702879	12	-	26472758	Raji	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	-0.32433270505187467	[231]	[42]	-3	hSpCas9	negative selection	525362
51705533	51705556	12	+	26472758	Raji	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	-0.246253419241101	[91]	[17]	-2	hSpCas9	negative selection	525363
51706552	51706575	12	+	26472758	Raji	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-2.699971386684005	[27]	[0]	-9	hSpCas9	negative selection	525364
51706601	51706624	12	+	26472758	Raji	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	-0.2520192649324257	[194]	[37]	-2	hSpCas9	negative selection	525365
51721675	51721698	12	+	26472758	Raji	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	0.2210403171691665	[121]	[32]	2	hSpCas9	negative selection	525366
51721698	51721721	12	-	26472758	Raji	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-0.8926164646264008	[7]	[0]	-6	hSpCas9	negative selection	525367
51721662	51721685	12	+	26472758	K562	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	-0.5878538265954866	[218]	[122]	-4	hSpCas9	negative selection	716476
51721818	51721841	12	+	26472758	K562	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.4008202850090139	[130]	[145]	3	hSpCas9	negative selection	716477
51769122	51769145	12	-	26472758	K562	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	-0.6095030128456085	[243]	[134]	-4	hSpCas9	negative selection	716478
51662807	51662830	12	+	26472758	K562	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	-0.11106192693194211	[521]	[407]	-1	hSpCas9	negative selection	716479
51702856	51702879	12	-	26472758	K562	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	0.693844952490211	[341]	[466]	6	hSpCas9	negative selection	716480
51705533	51705556	12	+	26472758	K562	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	-0.15834044183396045	[155]	[117]	-1	hSpCas9	negative selection	716481
51706552	51706575	12	+	26472758	K562	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-1.9131225493200326	[57]	[12]	-7	hSpCas9	negative selection	716482
51706601	51706624	12	+	26472758	K562	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	-2.704955199263585	[447]	[57]	-8	hSpCas9	negative selection	716483
51721675	51721698	12	+	26472758	K562	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	-0.22951246066596548	[274]	[197]	-1	hSpCas9	negative selection	716484
51721698	51721721	12	-	26472758	K562	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-3.662471867942072	[44]	[2]	-9	hSpCas9	negative selection	716485
51662973	51662996	12	+	26627737	DLD1	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.635042096154529	[284]	[122,21,247]	6	hSpCas9	negative selection	784169
51702765	51702788	12	+	26627737	DLD1	viability	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	0.6376649068391398	[112]	[40,83,42]	6	hSpCas9	negative selection	784171
51705590	51705613	12	+	26627737	DLD1	viability	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	1.911403444457313	[89]	[58,179,84]	9	hSpCas9	negative selection	784172
51706526	51706549	12	+	26627737	DLD1	viability	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	0.3267193972224429	[296]	[145,114,91]	3	hSpCas9	negative selection	784173
51721659	51721682	12	+	26627737	DLD1	viability	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.6824488920276102	[1474]	[680,675,843]	6	hSpCas9	negative selection	784175
51745961	51745984	12	+	26627737	DLD1	viability	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.6096240846187935	[603]	[143,100,124]	-5	hSpCas9	negative selection	784176
51662973	51662996	12	+	26627737	GBM cells	viability after 5 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.832526477551784	[188]	[176,183]	9	hSpCas9	negative selection	866484
51702765	51702788	12	+	26627737	GBM cells	viability after 5 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-0.26709607655324363	[137]	[62,59]	-4	hSpCas9	negative selection	866486
51705590	51705613	12	+	26627737	GBM cells	viability after 5 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	0.42106026742024494	[132]	[53,136]	6	hSpCas9	negative selection	866487
51706526	51706549	12	+	26627737	GBM cells	viability after 5 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.40344685115417755	[237]	[82,109]	-6	hSpCas9	negative selection	866488
51721659	51721682	12	+	26627737	GBM cells	viability after 5 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.35856516539868544	[596]	[386,433]	5	hSpCas9	negative selection	866490
51745961	51745984	12	+	26627737	GBM cells	viability after 5 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.36674600035493143	[219]	[88,93]	-5	hSpCas9	negative selection	866491
51662973	51662996	12	+	26627737	GBM cells	viability after 13 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.9063141866460995	[188]	[173,206]	9	hSpCas9	negative selection	948799
51702765	51702788	12	+	26627737	GBM cells	viability after 13 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-0.6790731242783431	[137]	[59,35]	-7	hSpCas9	negative selection	948801
51705590	51705613	12	+	26627737	GBM cells	viability after 13 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.05484890377592411	[132]	[42,90]	0	hSpCas9	negative selection	948802
51706526	51706549	12	+	26627737	GBM cells	viability after 13 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	0.13449028521273293	[237]	[197,95]	1	hSpCas9	negative selection	948803
51721659	51721682	12	+	26627737	GBM cells	viability after 13 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.43127704641164333	[596]	[481,399]	5	hSpCas9	negative selection	948805
51745961	51745984	12	+	26627737	GBM cells	viability after 13 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.12321067631802049	[219]	[129,92]	-1	hSpCas9	negative selection	948806
51662973	51662996	12	+	26627737	GBM cells	viability after 21 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.5085837886341673	[188]	[155,136]	5	hSpCas9	negative selection	1031114
51702765	51702788	12	+	26627737	GBM cells	viability after 21 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-0.36727319881418896	[137]	[66,49]	-3	hSpCas9	negative selection	1031116
51705590	51705613	12	+	26627737	GBM cells	viability after 21 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	0.43343158691133565	[132]	[83,109]	4	hSpCas9	negative selection	1031117
51706526	51706549	12	+	26627737	GBM cells	viability after 21 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.2616277834087777	[237]	[122,93]	-2	hSpCas9	negative selection	1031118
51721659	51721682	12	+	26627737	GBM cells	viability after 21 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.22152457130203462	[596]	[385,370]	2	hSpCas9	negative selection	1031120
51745961	51745984	12	+	26627737	GBM cells	viability after 21 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.4866994564111893	[219]	[167,166]	5	hSpCas9	negative selection	1031121
51662973	51662996	12	+	26627737	RPE1	viability after 9 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	3.62186927755113	[115]	[333,592]	9	hSpCas9	negative selection	1113429
51702765	51702788	12	+	26627737	RPE1	viability after 9 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	1.3183465670483188	[124]	[80,118]	7	hSpCas9	negative selection	1113431
51705590	51705613	12	+	26627737	RPE1	viability after 9 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.9662299906177328	[516]	[36,141]	-6	hSpCas9	negative selection	1113432
51706526	51706549	12	+	26627737	RPE1	viability after 9 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.22205065326415346	[648]	[85,287]	-1	hSpCas9	negative selection	1113433
51721659	51721682	12	+	26627737	RPE1	viability after 9 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.7289957089232741	[2271]	[1095,1285]	5	hSpCas9	negative selection	1113435
51745961	51745984	12	+	26627737	RPE1	viability after 9 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	1.3509270721875728	[413]	[320,342]	7	hSpCas9	negative selection	1113436
51662973	51662996	12	+	26627737	RPE1	viability after 12 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	3.2527270854504753	[115]	[349,240]	9	hSpCas9	negative selection	1195744
51702765	51702788	12	+	26627737	RPE1	viability after 12 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	1.3474563051854367	[124]	[83,86]	7	hSpCas9	negative selection	1195746
51705590	51705613	12	+	26627737	RPE1	viability after 12 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.1557566892631561	[516]	[28,225]	-1	hSpCas9	negative selection	1195747
51706526	51706549	12	+	26627737	RPE1	viability after 12 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.46182966178502177	[648]	[61,194]	-3	hSpCas9	negative selection	1195748
51721659	51721682	12	+	26627737	RPE1	viability after 12 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.8485274844074668	[2271]	[1103,1093]	5	hSpCas9	negative selection	1195750
51745961	51745984	12	+	26627737	RPE1	viability after 12 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	1.584476366713233	[413]	[352,312]	8	hSpCas9	negative selection	1195751
51662973	51662996	12	+	26627737	RPE1	viability after 15 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	3.8776861641837	[115]	[687,283]	9	hSpCas9	negative selection	1278059
51702765	51702788	12	+	26627737	RPE1	viability after 15 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	1.528133907215966	[124]	[102,100]	7	hSpCas9	negative selection	1278061
51705590	51705613	12	+	26627737	RPE1	viability after 15 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.7493656185066208	[516]	[58,113]	-5	hSpCas9	negative selection	1278062
51706526	51706549	12	+	26627737	RPE1	viability after 15 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.0021844699743173712	[648]	[193,172]	0	hSpCas9	negative selection	1278063
51721659	51721682	12	+	26627737	RPE1	viability after 15 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	1.2439023647235121	[2271]	[1878,1177]	7	hSpCas9	negative selection	1278065
51745961	51745984	12	+	26627737	RPE1	viability after 15 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	1.7144818750716584	[413]	[477,293]	8	hSpCas9	negative selection	1278066
51662973	51662996	12	+	26627737	RPE1	viability after 18 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	3.5683626190159474	[115]	[410,328]	9	hSpCas9	negative selection	1360374
51702765	51702788	12	+	26627737	RPE1	viability after 18 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	0.7269591701190237	[124]	[50,60]	4	hSpCas9	negative selection	1360376
51705590	51705613	12	+	26627737	RPE1	viability after 18 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.41232241397872815	[516]	[70,140]	-3	hSpCas9	negative selection	1360377
51706526	51706549	12	+	26627737	RPE1	viability after 18 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.903283282863681	[648]	[24,166]	-5	hSpCas9	negative selection	1360378
51721659	51721682	12	+	26627737	RPE1	viability after 18 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	1.3423825452162421	[2271]	[1386,1733]	7	hSpCas9	negative selection	1360380
51745961	51745984	12	+	26627737	RPE1	viability after 18 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	1.53114822567324	[413]	[290,356]	7	hSpCas9	negative selection	1360381
51662973	51662996	12	+	26627737	HeLa	viability after 8 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.6353200415427115	[348]	[146,214,319]	5	hSpCas9	negative selection	1442689
51702765	51702788	12	+	26627737	HeLa	viability after 8 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-1.3055570702145984	[236]	[45,21,56]	-8	hSpCas9	negative selection	1442691
51705590	51705613	12	+	26627737	HeLa	viability after 8 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	0.3231178655898468	[242]	[200,93,117]	3	hSpCas9	negative selection	1442692
51706526	51706549	12	+	26627737	HeLa	viability after 8 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	0.18194498918530036	[303]	[230,86,149]	1	hSpCas9	negative selection	1442693
51721659	51721682	12	+	26627737	HeLa	viability after 8 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	1.1423717756139162	[820]	[646,963,727]	8	hSpCas9	negative selection	1442695
51745961	51745984	12	+	26627737	HeLa	viability after 8 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-1.173585040666751	[548]	[151,160,20]	-8	hSpCas9	negative selection	1442696
51662973	51662996	12	+	26627737	HeLa	viability after 12 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.1470190424407394	[348]	[47,180,153]	-1	hSpCas9	negative selection	1525004
51702765	51702788	12	+	26627737	HeLa	viability after 12 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-0.34252568501364755	[236]	[131,51,51]	-3	hSpCas9	negative selection	1525006
51705590	51705613	12	+	26627737	HeLa	viability after 12 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.8497281116548269	[242]	[89,28,51]	-6	hSpCas9	negative selection	1525007
51706526	51706549	12	+	26627737	HeLa	viability after 12 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	0.04530980007620339	[303]	[95,147,141]	0	hSpCas9	negative selection	1525008
51721659	51721682	12	+	26627737	HeLa	viability after 12 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	1.3196941017713402	[820]	[749,883,899]	8	hSpCas9	negative selection	1525010
51745961	51745984	12	+	26627737	HeLa	viability after 12 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-1.176605837547005	[548]	[57,136,100]	-8	hSpCas9	negative selection	1525011
51662973	51662996	12	+	26627737	HeLa	viability after 15 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.3978944789319032	[348]	[100,258,203]	3	hSpCas9	negative selection	1607319
51702765	51702788	12	+	26627737	HeLa	viability after 15 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-0.969684685782702	[236]	[37,59,49]	-7	hSpCas9	negative selection	1607321
51705590	51705613	12	+	26627737	HeLa	viability after 15 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.2024287994348456	[242]	[42,86,131]	-2	hSpCas9	negative selection	1607322
51706526	51706549	12	+	26627737	HeLa	viability after 15 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	0.2471867063296567	[303]	[252,42,142]	2	hSpCas9	negative selection	1607323
51721659	51721682	12	+	26627737	HeLa	viability after 15 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	1.5034144297831855	[820]	[1177,590,1080]	8	hSpCas9	negative selection	1607325
51745961	51745984	12	+	26627737	HeLa	viability after 15 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.5698205745690342	[548]	[105,162,185]	-5	hSpCas9	negative selection	1607326
51662973	51662996	12	+	26627737	HeLa	viability after 18 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.3949809837312289	[348]	[68,211,203]	3	hSpCas9	negative selection	1689634
51702765	51702788	12	+	26627737	HeLa	viability after 18 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-1.0162236571026309	[236]	[22,48,49]	-7	hSpCas9	negative selection	1689636
51705590	51705613	12	+	26627737	HeLa	viability after 18 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.21527224300125714	[242]	[28,69,131]	-2	hSpCas9	negative selection	1689637
51706526	51706549	12	+	26627737	HeLa	viability after 18 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	0.28388438009187766	[303]	[175,36,142]	2	hSpCas9	negative selection	1689638
51721659	51721682	12	+	26627737	HeLa	viability after 18 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	1.5369210690969723	[820]	[829,493,1080]	8	hSpCas9	negative selection	1689640
51745961	51745984	12	+	26627737	HeLa	viability after 18 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.5712847874445035	[548]	[73,130,185]	-5	hSpCas9	negative selection	1689641
51662973	51662996	12	+	26627737	HCT116	viability after 6 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	1.3964194828639476	[544]	[153,264]	7	hSpCas9	negative selection	1771949
51702765	51702788	12	+	26627737	HCT116	viability after 6 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-1.769223760657081	[92]	[2,4]	-7	hSpCas9	negative selection	1771951
51705590	51705613	12	+	26627737	HCT116	viability after 6 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	1.0890709029538987	[398]	[291,45]	6	hSpCas9	negative selection	1771952
51706526	51706549	12	+	26627737	HCT116	viability after 6 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.5144752398157535	[293]	[32,31]	-3	hSpCas9	negative selection	1771953
51721659	51721682	12	+	26627737	HCT116	viability after 6 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.5761275771707672	[2212]	[809,357]	3	hSpCas9	negative selection	1771955
51745961	51745984	12	+	26627737	HCT116	viability after 6 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.7722606168071399	[799]	[344,142]	4	hSpCas9	negative selection	1771956
51662973	51662996	12	+	26627737	HCT116	viability after 8 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.33548164458649404	[213]	[158,92,193]	3	hSpCas9	negative selection	1854264
51702765	51702788	12	+	26627737	HCT116	viability after 8 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-0.4502372933351919	[91]	[69,12,28]	-5	hSpCas9	negative selection	1854266
51705590	51705613	12	+	26627737	HCT116	viability after 8 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.20203152939285954	[266]	[133,137,111]	-2	hSpCas9	negative selection	1854267
51706526	51706549	12	+	26627737	HCT116	viability after 8 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.6148719038709991	[355]	[157,113,112]	-6	hSpCas9	negative selection	1854268
51721659	51721682	12	+	26627737	HCT116	viability after 8 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	-0.12283457893725602	[1352]	[584,758,707]	-1	hSpCas9	negative selection	1854270
51745961	51745984	12	+	26627737	HCT116	viability after 8 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.21289991240094375	[251]	[130,139,88]	-2	hSpCas9	negative selection	1854271
51662973	51662996	12	+	26627737	HCT116	viability after 9 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.2587916199847471	[544]	[296,76]	2	hSpCas9	negative selection	1936579
51702765	51702788	12	+	26627737	HCT116	viability after 9 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	1.444090014165937	[92]	[147,3]	8	hSpCas9	negative selection	1936581
51705590	51705613	12	+	26627737	HCT116	viability after 9 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.4928105445459374	[398]	[149,16]	-3	hSpCas9	negative selection	1936582
51706526	51706549	12	+	26627737	HCT116	viability after 9 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	1.11593115517287	[293]	[163,174]	7	hSpCas9	negative selection	1936583
51721659	51721682	12	+	26627737	HCT116	viability after 9 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	-0.15778340204468067	[2212]	[503,549]	-1	hSpCas9	negative selection	1936585
51745961	51745984	12	+	26627737	HCT116	viability after 9 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-2.268253302313202	[799]	[83,12]	-9	hSpCas9	negative selection	1936586
51662973	51662996	12	+	26627737	HCT116	viability after 12 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.03315103323085444	[213]	[142,82,115]	0	hSpCas9	negative selection	2018894
51702765	51702788	12	+	26627737	HCT116	viability after 12 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	0.10439150413455756	[91]	[31,64,60]	1	hSpCas9	negative selection	2018896
51705590	51705613	12	+	26627737	HCT116	viability after 12 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.728529286796707	[266]	[41,92,122]	-7	hSpCas9	negative selection	2018897
51706526	51706549	12	+	26627737	HCT116	viability after 12 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.46213713391033884	[355]	[97,104,206]	-5	hSpCas9	negative selection	2018898
51721659	51721682	12	+	26627737	HCT116	viability after 12 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	-0.056984417882878	[1352]	[752,625,663]	0	hSpCas9	negative selection	2018900
51745961	51745984	12	+	26627737	HCT116	viability after 12 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.46471440768347005	[251]	[162,222,164]	4	hSpCas9	negative selection	2018901
51662973	51662996	12	+	26627737	HCT116	viability after 15 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.4781902236884253	[213]	[259,59,203]	4	hSpCas9	negative selection	2101209
51702765	51702788	12	+	26627737	HCT116	viability after 15 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	0.13524977826707318	[91]	[86,64,25]	1	hSpCas9	negative selection	2101211
51705590	51705613	12	+	26627737	HCT116	viability after 15 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.32200025429976875	[266]	[83,132,145]	-3	hSpCas9	negative selection	2101212
51706526	51706549	12	+	26627737	HCT116	viability after 15 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-1.012324401426906	[355]	[153,98,57]	-7	hSpCas9	negative selection	2101213
51721659	51721682	12	+	26627737	HCT116	viability after 15 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	-0.07914240379149229	[1352]	[962,758,514]	-1	hSpCas9	negative selection	2101215
51745961	51745984	12	+	26627737	HCT116	viability after 15 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.5367114609083317	[251]	[186,226,212]	5	hSpCas9	negative selection	2101216
51662973	51662996	12	+	26627737	HCT116	viability after 18 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.2582419622907032	[213]	[128,131,108]	2	hSpCas9	negative selection	2183524
51702765	51702788	12	+	26627737	HCT116	viability after 18 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	0.32558582783334566	[91]	[77,56,30]	3	hSpCas9	negative selection	2183526
51705590	51705613	12	+	26627737	HCT116	viability after 18 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	0.3155134973435517	[266]	[152,162,165]	2	hSpCas9	negative selection	2183527
51706526	51706549	12	+	26627737	HCT116	viability after 18 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.6611429831071085	[355]	[97,91,138]	-6	hSpCas9	negative selection	2183528
51721659	51721682	12	+	26627737	HCT116	viability after 18 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.16402134038956762	[1352]	[688,875,618]	1	hSpCas9	negative selection	2183530
51745961	51745984	12	+	26627737	HCT116	viability after 18 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.47311957577447616	[251]	[112,254,131]	4	hSpCas9	negative selection	2183531
51620941	51620964	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	TACACCACTGCATTCCAGCCTGG	SCN8A	ENSG00000196876	0.5914306786217665	[214,131]	[58,55]	2	dCas9-VP64	positive selection	2387208
51731342	51731365	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATCGCTTGAACATAG	SCN8A	ENSG00000196876	6.121120684117956	[31,90]	[7,1976]	9	dCas9-VP64	positive selection	2387375
51591091	51591114	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCCGCGCGCGCCCCCTGCCCGG	SCN8A	ENSG00000196876	-1.1056099466951044	[218,9]	[18,2]	-6	dCas9-VP64	positive selection	2407613
51591136	51591159	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGGGGGGCCCGGCAGTAGGGG	SCN8A	ENSG00000196876	0.8029567478239653	[4,87]	[10,24]	3	dCas9-VP64	positive selection	2407614
51591073	51591096	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCGGGCCGGGGCCGGCCCGGG	SCN8A	ENSG00000196876	-1.03545473404813	[17,100]	[5,5]	-6	dCas9-VP64	positive selection	2407615
51612973	51612996	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATTTCAGCACTTTGGGAGGCAG	SCN8A	ENSG00000196876	0.4920406076216166	[38,113]	[3,44]	2	dCas9-VP64	positive selection	2409964
51604775	51604798	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTTTGGGAGGCCAAGGCAGCGG	SCN8A	ENSG00000196876	2.0119762381202047	[93,200]	[9,263]	7	dCas9-VP64	positive selection	2462446
51620941	51620964	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	TACACCACTGCATTCCAGCCTGG	SCN8A	ENSG00000196876	-0.37747874830615435	[626,633]	[195,122]	-4	dCas9-VP64	positive selection	2482463
51731342	51731365	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATCGCTTGAACATAG	SCN8A	ENSG00000196876	1.1434369151352513	[54,74]	[73,20]	7	dCas9-VP64	positive selection	2482630
51591091	51591114	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCCGCGCGCGCCCCCTGCCCGG	SCN8A	ENSG00000196876	-0.10132831399388684	[105,103]	[22,39]	-1	dCas9-VP64	positive selection	2502868
51591136	51591159	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGGGGGGCCCGGCAGTAGGGG	SCN8A	ENSG00000196876	-0.004088496261698715	[19,28]	[5,7]	0	dCas9-VP64	positive selection	2502869
51591073	51591096	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCGGGCCGGGGCCGGCCCGGG	SCN8A	ENSG00000196876	1.064174585937859	[1,17]	[2,9]	6	dCas9-VP64	positive selection	2502870
51612973	51612996	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATTTCAGCACTTTGGGAGGCAG	SCN8A	ENSG00000196876	1.405058588213125	[134,129]	[221,14]	7	dCas9-VP64	positive selection	2505219
51604775	51604798	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTTTGGGAGGCCAAGGCAGCGG	SCN8A	ENSG00000196876	-0.4547686614086857	[146,265]	[55,41]	-5	dCas9-VP64	positive selection	2557701
51706500	51706523	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGATTTCAGAAGAGCTCCGAGG	SCN8A	ENSG00000196876	0.031235098280481738	[4,4]	[4,2]	0	hSpCas9	positive selection	3018998
51706498	51706521	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATTTCAGAAGAGCTCCGAGGGG	SCN8A	ENSG00000196876	0.13245121993443806	[4,4]	[3,4]	2	hSpCas9	positive selection	3018999
51705549	51705572	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGGAGGCAGAACAAAAAGAGG	SCN8A	ENSG00000196876	0.3347366486589657	[4,5]	[4,6]	7	hSpCas9	positive selection	3019000
51721698	51721721	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-0.6689844636852529	[1,2]	[1,0]	-7	hSpCas9	positive selection	3019001
51706500	51706523	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGATTTCAGAAGAGCTCCGAGG	SCN8A	ENSG00000196876	-0.16661448095691755	[4,4]	[3,1]	-2	hSpCas9	positive selection	3086856
51706498	51706521	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATTTCAGAAGAGCTCCGAGGGG	SCN8A	ENSG00000196876	-0.5394811950716816	[4,4]	[4,0]	-7	hSpCas9	positive selection	3086857
51705549	51705572	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGGAGGCAGAACAAAAAGAGG	SCN8A	ENSG00000196876	0.008381154832502513	[4,4]	[5,2]	0	hSpCas9	positive selection	3086858
51721698	51721721	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-0.012792457914883593	[1,1]	[0,1]	0	hSpCas9	positive selection	3086859
51662943	51662966		+	24336571	A375	resistance to PLX after 7 days	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.17437741110224558	[24,24]	[23,20]	-5	hSpCas9	positive selection	3142906
51662936	51662959		-	24336571	A375	resistance to PLX after 7 days	GTCCTCCCGATGACTGCCATCGG	SCN8A	ENSG00000196876	-0.03784507305117435	[63,56]	[56,59]	-1	hSpCas9	positive selection	3142907
51687083	51687106		+	24336571	A375	resistance to PLX after 7 days	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.12286071513307872	[57,62]	[55,53]	-4	hSpCas9	positive selection	3142908
51662943	51662966		+	24336571	A375	resistance to PLX after 14 days	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.1746736638476325	[18,28]	[9,14]	1	hSpCas9	positive selection	3200699
51662936	51662959		-	24336571	A375	resistance to PLX after 14 days	GTCCTCCCGATGACTGCCATCGG	SCN8A	ENSG00000196876	0.11339355677723839	[62,46]	[29,24]	1	hSpCas9	positive selection	3200700
51687083	51687106		+	24336571	A375	resistance to PLX after 14 days	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.19211484775356658	[62,69]	[30,22]	-2	hSpCas9	positive selection	3200701
51662943	51662966		+	24336571	A375	viability after 7 days	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.030141799228165067	[25]	[24,24]	0	hSpCas9	negative selection	3258492
51662936	51662959		-	24336571	A375	viability after 7 days	GTCCTCCCGATGACTGCCATCGG	SCN8A	ENSG00000196876	1.4052598554233913	[23]	[63,56]	9	hSpCas9	negative selection	3258493
51687083	51687106		+	24336571	A375	viability after 7 days	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.5858191626252827	[41]	[57,62]	8	hSpCas9	negative selection	3258494
51662943	51662966		+	24336571	A375	viability after 14 days	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.009237316483319269	[25]	[18,28]	0	hSpCas9	negative selection	3316285
51662936	51662959		-	24336571	A375	viability after 14 days	GTCCTCCCGATGACTGCCATCGG	SCN8A	ENSG00000196876	1.2895134820832284	[23]	[62,46]	9	hSpCas9	negative selection	3316286
51687083	51687106		+	24336571	A375	viability after 14 days	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.7406061277571327	[41]	[62,69]	8	hSpCas9	negative selection	3316287
51687083	51687106	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.1478152516905089	[338,338]	[1,1]	-1	hSpCas9	positive selection	3391447
51699691	51699714	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.3148117061065953	[122,122]	[0,0]	1	hSpCas9	positive selection	3391448
51687125	51687148	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	-0.851198245332334	[275,275]	[0,0]	-6	hSpCas9	positive selection	3391449
51706500	51706523	12	-	26780180	HT29	viability (Avana library 4 designs)	GAGATTTCAGAAGAGCTCCGAGG	SCN8A	ENSG00000196876	0.776384823095399	[]	[]	3	hSpCas9	negative selection	3457425
51706498	51706521	12	-	26780180	HT29	viability (Avana library 4 designs)	GATTTCAGAAGAGCTCCGAGGGG	SCN8A	ENSG00000196876	-0.0512993386296865	[]	[]	-1	hSpCas9	negative selection	3457426
51705548	51705571	12	+	26780180	HT29	viability (Avana library 4 designs)	GGAGGAGGCAGAACAAAAAGAGG	SCN8A	ENSG00000196876	0.359799645495642	[]	[]	1	hSpCas9	negative selection	3457427
51721698	51721721	12	-	26780180	HT29	viability (Avana library 4 designs)	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	1.64988030201934	[]	[]	6	hSpCas9	negative selection	3457428
51706498	51706521	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATTTCAGAAGAGCTCCGAGGGG	SCN8A	ENSG00000196876	-0.9835317967694	[]	[]	-1	hSpCas9	negative selection	3556375
51706500	51706523	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGATTTCAGAAGAGCTCCGAGG	SCN8A	ENSG00000196876	4.24724830905509	[]	[]	7	hSpCas9	negative selection	3556376
51721698	51721721	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	4.45400220491472	[]	[]	7	hSpCas9	negative selection	3556377
51705548	51705571	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGAGGCAGAACAAAAAGAGG	SCN8A	ENSG00000196876	-0.886699320081836	[]	[]	-1	hSpCas9	negative selection	3556378
51663056	51663079	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTATGGGTCAAAGTCCTCCAGGG	SCN8A	ENSG00000196876	0.745267608272584	[]	[]	1	hSpCas9	negative selection	3556379
51686432	51686455	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACATTCTTCGACCAGTCAGGAGG	SCN8A	ENSG00000196876	0.954518822704587	[]	[]	1	hSpCas9	negative selection	3556380
51706498	51706521	12	-	26780180	A375	viability (Avana lentiGuide)	GATTTCAGAAGAGCTCCGAGGGG	SCN8A	ENSG00000196876	-4.14677804654075	[]	[]	-7	hSpCas9	negative selection	3665034
51706500	51706523	12	-	26780180	A375	viability (Avana lentiGuide)	GAGATTTCAGAAGAGCTCCGAGG	SCN8A	ENSG00000196876	0.613809805072693	[]	[]	0	hSpCas9	negative selection	3665035
51721698	51721721	12	-	26780180	A375	viability (Avana lentiGuide)	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	15.3250705556377	[]	[]	8	hSpCas9	negative selection	3665036
51705548	51705571	12	+	26780180	A375	viability (Avana lentiGuide)	GGAGGAGGCAGAACAAAAAGAGG	SCN8A	ENSG00000196876	-3.44587029328819	[]	[]	-6	hSpCas9	negative selection	3665037
51663056	51663079	12	-	26780180	A375	viability (Avana lentiGuide)	GTATGGGTCAAAGTCCTCCAGGG	SCN8A	ENSG00000196876	12.1063388343448	[]	[]	7	hSpCas9	negative selection	3665038
51686432	51686455	12	-	26780180	A375	viability (Avana lentiGuide)	ACATTCTTCGACCAGTCAGGAGG	SCN8A	ENSG00000196876	-0.739486774921599	[]	[]	-1	hSpCas9	negative selection	3665039
51706498	51706521	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTTCAGAAGAGCTCCGAGGGG	SCN8A	ENSG00000196876	0.026937241874310014	[5]	[6,5]	0	hSpCas9	positive selection	3773641
51706500	51706523	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGATTTCAGAAGAGCTCCGAGG	SCN8A	ENSG00000196876	0.17615730206519553	[5]	[7,5]	5	hSpCas9	positive selection	3773642
51721698	51721721	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-0.015170735860766227	[3]	[3,3]	0	hSpCas9	positive selection	3773643
51705548	51705571	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGAGGCAGAACAAAAAGAGG	SCN8A	ENSG00000196876	0.032546242654973974	[5]	[5,4]	0	hSpCas9	positive selection	3773644
51663056	51663079	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATGGGTCAAAGTCCTCCAGGG	SCN8A	ENSG00000196876	-0.18401341850495034	[4]	[3,4]	-3	hSpCas9	positive selection	3773645
51686432	51686455	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATTCTTCGACCAGTCAGGAGG	SCN8A	ENSG00000196876	0.1221254504007813	[4]	[5,4]	3	hSpCas9	positive selection	3773646
51706498	51706521	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTTCAGAAGAGCTCCGAGGGG	SCN8A	ENSG00000196876	0.14099567415607922	[5]	[5,5]	3	hSpCas9	positive selection	3882248
51706500	51706523	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGATTTCAGAAGAGCTCCGAGG	SCN8A	ENSG00000196876	0.05667508910228908	[6]	[6,3]	1	hSpCas9	positive selection	3882249
51721698	51721721	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	0.10918039856898559	[3]	[3,2]	2	hSpCas9	positive selection	3882250
51705548	51705571	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGAGGCAGAACAAAAAGAGG	SCN8A	ENSG00000196876	0.23542039916924282	[6]	[6,5]	6	hSpCas9	positive selection	3882251
51663056	51663079	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATGGGTCAAAGTCCTCCAGGG	SCN8A	ENSG00000196876	0.12873185997500342	[5]	[4,4]	3	hSpCas9	positive selection	3882252
51686432	51686455	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATTCTTCGACCAGTCAGGAGG	SCN8A	ENSG00000196876	0.05683446440886042	[5]	[5,3]	1	hSpCas9	positive selection	3882253
51699691	51699714	12	-	26780180	A375	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.458899231063075	[]	[]	1	hSpCas9	negative selection	3992274
51699717	51699740	12	-	26780180	A375	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.881619072621752	[]	[]	3	hSpCas9	negative selection	3992275
51662943	51662966	12	+	26780180	A375	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.809443488299824	[]	[]	3	hSpCas9	negative selection	3992276
51687125	51687148	12	+	26780180	A375	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.538407165867091	[]	[]	1	hSpCas9	negative selection	3992277
51662973	51662996	12	+	26780180	A375	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	1.13583575432298	[]	[]	6	hSpCas9	negative selection	3992278
51687083	51687106	12	+	26780180	A375	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.839894068827858	[]	[]	3	hSpCas9	negative selection	3992279
51699691	51699714	12	-	26780180	HT29	viability (GeCKOv2 library)	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	1.43223719787151	[]	[]	7	hSpCas9	negative selection	4100240
51699717	51699740	12	-	26780180	HT29	viability (GeCKOv2 library)	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	1.21187976955578	[]	[]	6	hSpCas9	negative selection	4100241
51662943	51662966	12	+	26780180	HT29	viability (GeCKOv2 library)	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.674955612710318	[]	[]	2	hSpCas9	negative selection	4100242
51687125	51687148	12	+	26780180	HT29	viability (GeCKOv2 library)	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.475535195384762	[]	[]	1	hSpCas9	negative selection	4100243
51662973	51662996	12	+	26780180	HT29	viability (GeCKOv2 library)	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.761710550760053	[]	[]	3	hSpCas9	negative selection	4100244
51687083	51687106	12	+	26780180	HT29	viability (GeCKOv2 library)	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.97756702922748	[]	[]	4	hSpCas9	negative selection	4100245
51662943	51662966	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.2745449185026617	[4]	[3,3]	6	hSpCas9	positive selection	4168693
51662936	51662959	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCCTCCCGATGACTGCCATCGG	SCN8A	ENSG00000196876	0.211663025966993	[5]	[3,4]	5	hSpCas9	positive selection	4168694
51687083	51687106	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.6902898898459253	[5]	[7,4]	9	hSpCas9	positive selection	4168695
51662943	51662966	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	1.0072559830136143	[4]	[4,3,3,4]	7	hSpCas9	positive selection	4232715
51662936	51662959	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCCTCCCGATGACTGCCATCGG	SCN8A	ENSG00000196876	0.16622398087981816	[4]	[3,4,1,0]	1	hSpCas9	positive selection	4232716
51687083	51687106	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.9534036137119212	[5]	[1,4,5,4]	6	hSpCas9	positive selection	4232717
51662943	51662966	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.002738191007953583	[3]	[3,1]	0	hSpCas9	positive selection	4296634
51699717	51699740	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.21738509222161262	[3]	[3,2]	4	hSpCas9	positive selection	4296635
51662973	51662996	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.1776196192151473	[2]	[1,1]	-4	hSpCas9	positive selection	4296636
51687083	51687106	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.027536978890363217	[3]	[3,2]	0	hSpCas9	positive selection	4360888
51699691	51699714	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.11291417709723224	[2]	[3,0]	2	hSpCas9	positive selection	4360889
51687125	51687148	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.17516015031311893	[3]	[4,2]	3	hSpCas9	positive selection	4360890
51721881	51721903	12	-	27760321	OCIAML3	viability	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	-0.03157359926295111	[1050,863]	[726,731]	0	hSpCas9	negative selection	4437235
51745962	51745984	12	+	27760321	OCIAML3	viability	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.20912936891230705	[769,622]	[545,730]	2	hSpCas9	negative selection	4437236
51762623	51762645	12	+	27760321	OCIAML3	viability	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	0.22305497617955666	[582,494]	[406,598]	2	hSpCas9	negative selection	4437237
51765911	51765933	12	+	27760321	OCIAML3	viability	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	0.46664456947977895	[657,638]	[608,823]	5	hSpCas9	negative selection	4437238
51688801	51688823	12	+	27760321	OCIAML3	viability	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.3964894110463414	[697,560]	[557,756]	5	hSpCas9	negative selection	4437239
51721881	51721903	12	-	27760321	OCIAML2	viability	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	0.2418743834747452	[1050,863]	[798,1059]	3	hSpCas9	negative selection	4520698
51745962	51745984	12	+	27760321	OCIAML2	viability	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.33451369784169915	[769,622]	[380,527]	-4	hSpCas9	negative selection	4520699
51762623	51762645	12	+	27760321	OCIAML2	viability	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	-0.049046233019340524	[582,494]	[375,477]	0	hSpCas9	negative selection	4520700
51765911	51765933	12	+	27760321	OCIAML2	viability	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	0.07373114189247765	[657,638]	[513,604]	0	hSpCas9	negative selection	4520701
51688801	51688823	12	+	27760321	OCIAML2	viability	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.42053152103593083	[697,560]	[716,625]	6	hSpCas9	negative selection	4520702
51721881	51721903	12	-	27760321	MV411	viability	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	-0.23108966309512546	[1050,863]	[520,557]	-2	hSpCas9	negative selection	4604161
51745962	51745984	12	+	27760321	MV411	viability	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.9549525733199005	[769,622]	[23,553]	-6	hSpCas9	negative selection	4604162
51762623	51762645	12	+	27760321	MV411	viability	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	-0.8805927057985152	[582,494]	[106,320]	-5	hSpCas9	negative selection	4604163
51765911	51765933	12	+	27760321	MV411	viability	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	0.5044341930772995	[657,638]	[527,728]	3	hSpCas9	negative selection	4604164
51688801	51688823	12	+	27760321	MV411	viability	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.29147124840700056	[697,560]	[433,612]	2	hSpCas9	negative selection	4604165
51721881	51721903	12	-	27760321	HL60	viability	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	0.3689526399885408	[1050,863]	[849,1169]	4	hSpCas9	negative selection	4687624
51745962	51745984	12	+	27760321	HL60	viability	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.38347948374365437	[769,622]	[443,422]	-4	hSpCas9	negative selection	4687625
51762623	51762645	12	+	27760321	HL60	viability	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	-0.970929629823837	[582,494]	[152,298]	-7	hSpCas9	negative selection	4687626
51765911	51765933	12	+	27760321	HL60	viability	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	0.033998668025656986	[657,638]	[609,472]	0	hSpCas9	negative selection	4687627
51688801	51688823	12	+	27760321	HL60	viability	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.09561441561404638	[697,560]	[524,568]	1	hSpCas9	negative selection	4687628
51721881	51721903	12	-	27760321	HT1080	viability	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	-0.43404925383190307	[863,673]	[252,197]	-2	hSpCas9	negative selection	4771087
51745962	51745984	12	+	27760321	HT1080	viability	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.09149121973995977	[622,485]	[168,307]	0	hSpCas9	negative selection	4771088
51762623	51762645	12	+	27760321	HT1080	viability	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	0.9724451355863198	[494,385]	[413,267]	5	hSpCas9	negative selection	4771089
51765911	51765933	12	+	27760321	HT1080	viability	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	-0.5020250887704738	[638,498]	[192,123]	-2	hSpCas9	negative selection	4771090
51688801	51688823	12	+	27760321	HT1080	viability	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.9147130488847657	[560,437]	[377,371]	5	hSpCas9	negative selection	4771091
51721881	51721903	12	-	27760321	HT29	viability after 7 days	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	0.5694095322775643	[863,673]	[1759,1340,1343]	8	hSpCas9	negative selection	4854550
51745962	51745984	12	+	27760321	HT29	viability after 7 days	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.14790967565252383	[622,485]	[599,482,833]	-2	hSpCas9	negative selection	4854551
51762623	51762645	12	+	27760321	HT29	viability after 7 days	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	-0.6761439245433554	[494,385]	[407,453,212]	-7	hSpCas9	negative selection	4854552
51765911	51765933	12	+	27760321	HT29	viability after 7 days	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	-0.4516657211748508	[638,498]	[550,604,452]	-6	hSpCas9	negative selection	4854553
51688801	51688823	12	+	27760321	HT29	viability after 7 days	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.5784769135050776	[560,437]	[768,1133,945]	8	hSpCas9	negative selection	4854554
51721881	51721903	12	-	27760321	HT29	viability after 25 days	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	0.7794091638281742	[863,673]	[1429,1484,1624]	8	hSpCas9	negative selection	4938013
51745962	51745984	12	+	27760321	HT29	viability after 25 days	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.16124103866989914	[622,485]	[643,722,767]	1	hSpCas9	negative selection	4938014
51762623	51762645	12	+	27760321	HT29	viability after 25 days	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	0.08705932289679436	[494,385]	[484,417,722]	0	hSpCas9	negative selection	4938015
51765911	51765933	12	+	27760321	HT29	viability after 25 days	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	-0.1284634465019775	[638,498]	[524,505,775]	-1	hSpCas9	negative selection	4938016
51688801	51688823	12	+	27760321	HT29	viability after 25 days	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.2967209662724118	[560,437]	[503,788,835]	3	hSpCas9	negative selection	4938017
51721881	51721903	12	-	27760321	HT29	viability after 22 days	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	0.6297131636205102	[863,673]	[1329,1379,1417]	7	hSpCas9	negative selection	5021476
51745962	51745984	12	+	27760321	HT29	viability after 22 days	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.41987802370474026	[622,485]	[923,875,769]	4	hSpCas9	negative selection	5021477
51762623	51762645	12	+	27760321	HT29	viability after 22 days	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	0.105484052323564	[494,385]	[392,568,686]	1	hSpCas9	negative selection	5021478
51765911	51765933	12	+	27760321	HT29	viability after 22 days	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	-0.3015079086971978	[638,498]	[369,666,568]	-3	hSpCas9	negative selection	5021479
51688801	51688823	12	+	27760321	HT29	viability after 22 days	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.28667984422762977	[560,437]	[463,1021,632]	3	hSpCas9	negative selection	5021480
51721881	51721903	12	-	27760321	HT29	viability after 19 days	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	0.7663812755889641	[863,673]	[1497,1758,1239]	7	hSpCas9	negative selection	5104939
51745962	51745984	12	+	27760321	HT29	viability after 19 days	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.34417940132458624	[622,485]	[537,1082,766]	3	hSpCas9	negative selection	5104940
51762623	51762645	12	+	27760321	HT29	viability after 19 days	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	0.3643868828382314	[494,385]	[946,210,811]	3	hSpCas9	negative selection	5104941
51765911	51765933	12	+	27760321	HT29	viability after 19 days	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	-0.20112355948846666	[638,498]	[625,614,466]	-2	hSpCas9	negative selection	5104942
51688801	51688823	12	+	27760321	HT29	viability after 19 days	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.3332388843571637	[560,437]	[831,526,807]	3	hSpCas9	negative selection	5104943
51721881	51721903	12	-	27760321	HT29	viability after 16 days	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	0.8596315825459182	[863,673]	[1945,1236,1544]	8	hSpCas9	negative selection	5188402
51745962	51745984	12	+	27760321	HT29	viability after 16 days	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.03380960805016231	[622,485]	[681,693,531]	0	hSpCas9	negative selection	5188403
51762623	51762645	12	+	27760321	HT29	viability after 16 days	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	-0.14995888133450047	[494,385]	[501,208,632]	-1	hSpCas9	negative selection	5188404
51765911	51765933	12	+	27760321	HT29	viability after 16 days	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	-0.29106861137840995	[638,498]	[573,631,356]	-3	hSpCas9	negative selection	5188405
51688801	51688823	12	+	27760321	HT29	viability after 16 days	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.3673792407243947	[560,437]	[612,1121,406]	4	hSpCas9	negative selection	5188406
51721881	51721903	12	-	27760321	HT29	viability after 13 days	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	0.8057946006998755	[863,673]	[1479,1513,1676]	9	hSpCas9	negative selection	5271865
51745962	51745984	12	+	27760321	HT29	viability after 13 days	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.3462630230954433	[622,485]	[679,777,984]	4	hSpCas9	negative selection	5271866
51762623	51762645	12	+	27760321	HT29	viability after 13 days	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	0.006567664430303155	[494,385]	[427,545,562]	0	hSpCas9	negative selection	5271867
51765911	51765933	12	+	27760321	HT29	viability after 13 days	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	-0.25657960197789825	[638,498]	[554,607,497]	-3	hSpCas9	negative selection	5271868
51688801	51688823	12	+	27760321	HT29	viability after 13 days	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.19999217774164973	[560,437]	[626,841,535]	2	hSpCas9	negative selection	5271869
51721881	51721903	12	-	27760321	HT29	viability after 10 days	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	0.5624767847363923	[863,673]	[1674,1333,1245]	7	hSpCas9	negative selection	5355328
51745962	51745984	12	+	27760321	HT29	viability after 10 days	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.061420405818288004	[622,485]	[699,729,736]	0	hSpCas9	negative selection	5355329
51762623	51762645	12	+	27760321	HT29	viability after 10 days	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	-0.13897398324419297	[494,385]	[355,537,602]	-2	hSpCas9	negative selection	5355330
51765911	51765933	12	+	27760321	HT29	viability after 10 days	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	-0.05176371092291909	[638,498]	[845,610,598]	0	hSpCas9	negative selection	5355331
51688801	51688823	12	+	27760321	HT29	viability after 10 days	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.352345468791539	[560,437]	[699,769,914]	5	hSpCas9	negative selection	5355332
51721881	51721903	12	-	27760321	MOLM13	viability	CAGGAGACGCCCGCCGATGTGG	SCN8A	ENSG00000196876	0.28116033371596716	[1050,863]	[688,622]	2	hSpCas9	negative selection	5438791
51745962	51745984	12	+	27760321	MOLM13	viability	CCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.09419681951774828	[769,622]	[420,413]	0	hSpCas9	negative selection	5438792
51762623	51762645	12	+	27760321	MOLM13	viability	GAACTGAGTCTAGCAGACGTGG	SCN8A	ENSG00000196876	0.6074217101706165	[582,494]	[377,532]	4	hSpCas9	negative selection	5438793
51765911	51765933	12	+	27760321	MOLM13	viability	GTCTTTCGAGTGTTGTGCGGGG	SCN8A	ENSG00000196876	0.8317000824892957	[657,638]	[308,944]	6	hSpCas9	negative selection	5438794
51688801	51688823	12	+	27760321	MOLM13	viability	CGCACTTTCAGGGTACTGAGGG	SCN8A	ENSG00000196876	0.8062621249448929	[697,560]	[441,766]	5	hSpCas9	negative selection	5438795
51591254	51591277	12	-	27661255	K562	viability	GCGGCGGGCGGGACTGCGGTGGG	SCN8A	ENSG00000196876	0.1566693347171909	[398,549]	[445,397]	5	dCas9-KRAB	negative selection	5509655
51591287	51591310	12	-	27661255	K562	viability	GAGGCGCGGCCGGACTGCAAAGG	SCN8A	ENSG00000196876	-0.03647545236546207	[1044,1141]	[960,755]	-1	dCas9-KRAB	negative selection	5509656
51591400	51591423	12	-	27661255	K562	viability	GGCGAGAAGGGAAACCCGGAGGG	SCN8A	ENSG00000196876	0.27150393283296465	[732,899]	[792,776]	8	dCas9-KRAB	negative selection	5509657
51591658	51591681	12	-	27661255	K562	viability	GCGGAAGGGGCACCAAGGACGGG	SCN8A	ENSG00000196876	0.2519311265110422	[244,258]	[266,215]	8	dCas9-KRAB	negative selection	5509658
51591671	51591694	12	-	27661255	K562	viability	GGAGGGCTGCACCGCGGAAGGGG	SCN8A	ENSG00000196876	0.2594975041354236	[1270,1513]	[1349,1307]	8	dCas9-KRAB	negative selection	5509659
51662943	51662966	12	+	27260156	BXPC3	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.061777924629762615	[703]	[741,663,605,813]	-1	hSpCas9	negative selection	5569094
51699717	51699740	12	-	27260156	BXPC3	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.18150802873582297	[528]	[445,593,786,712]	4	hSpCas9	negative selection	5569095
51662973	51662996	12	+	27260156	BXPC3	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.10352519159733853	[309]	[274,273,253,419]	-2	hSpCas9	negative selection	5569096
51687083	51687106	12	+	27260156	BXPC3	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.05405538508651975	[929]	[903,986,1006,1164]	1	hSpCas9	negative selection	5633348
51699691	51699714	12	-	27260156	BXPC3	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.1413597309598501	[344]	[302,316,426,579]	3	hSpCas9	negative selection	5633349
51687125	51687148	12	+	27260156	BXPC3	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	-0.05078387335769352	[881]	[706,761,1111,1021]	-1	hSpCas9	negative selection	5633350
51662943	51662966	12	+	27260156	A673	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.1095303741382746	[703]	[1003,879,920,848]	2	hSpCas9	negative selection	5690345
51699717	51699740	12	-	27260156	A673	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.17464272726825406	[528]	[643,685,734,797]	4	hSpCas9	negative selection	5690346
51662973	51662996	12	+	27260156	A673	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.06675748748728338	[309]	[332,289,443,351]	-2	hSpCas9	negative selection	5690347
51687083	51687106	12	+	27260156	A673	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.19412151276898082	[929]	[919,978,997,999]	-5	hSpCas9	negative selection	5754599
51699691	51699714	12	-	27260156	A673	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.04307125092410863	[344]	[490,431,381,407]	1	hSpCas9	negative selection	5754600
51687125	51687148	12	+	27260156	A673	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.016674646430204554	[881]	[1125,1025,903,1245]	0	hSpCas9	negative selection	5754601
51662943	51662966	12	+	27260156	A375	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.19011532660434827	[703]	[982,1140,1054,634]	2	hSpCas9	negative selection	5811596
51699717	51699740	12	-	27260156	A375	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.31573520893173557	[528]	[755,759,862,700]	4	hSpCas9	negative selection	5811597
51662973	51662996	12	+	27260156	A375	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.06580162937766498	[309]	[455,368,294,274]	-1	hSpCas9	negative selection	5811598
51687083	51687106	12	+	27260156	A375	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.03611603752753001	[929]	[1164,1473,866,1007]	0	hSpCas9	negative selection	5875850
51699691	51699714	12	-	27260156	A375	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.5310003506544583	[344]	[401,522,826,566]	7	hSpCas9	negative selection	5875851
51687125	51687148	12	+	27260156	A375	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.3556015788357739	[881]	[1589,1212,1311,1158]	5	hSpCas9	negative selection	5875852
51662943	51662966	12	+	27260156	COLO741	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.3508830068112826	[703]	[759,766,599]	-6	hSpCas9	negative selection	5932847
51699717	51699740	12	-	27260156	COLO741	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.26226748680611034	[528]	[968,896,593]	5	hSpCas9	negative selection	5932848
51662973	51662996	12	+	27260156	COLO741	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.16138229047560526	[309]	[205,454,385]	-3	hSpCas9	negative selection	5932849
51687083	51687106	12	+	27260156	COLO741	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.14676749600754668	[929]	[1267,1077,900]	-3	hSpCas9	negative selection	5997101
51699691	51699714	12	-	27260156	COLO741	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.05924308590437943	[344]	[419,527,427]	1	hSpCas9	negative selection	5997102
51687125	51687148	12	+	27260156	COLO741	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.2744869550093719	[881]	[1733,1215,1180]	6	hSpCas9	negative selection	5997103
51662943	51662966	12	+	27260156	CAL120	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.026115108478155125	[703]	[795,748,1022]	0	hSpCas9	negative selection	6054098
51699717	51699740	12	-	27260156	CAL120	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.17109828498092702	[528]	[775,574,874]	2	hSpCas9	negative selection	6054099
51662973	51662996	12	+	27260156	CAL120	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.3748064636600382	[309]	[325,916,235]	5	hSpCas9	negative selection	6054100
51687083	51687106	12	+	27260156	CAL120	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.08006738201154451	[929]	[1383,938,1367]	1	hSpCas9	negative selection	6118352
51699691	51699714	12	-	27260156	CAL120	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.2229327601120956	[344]	[517,681,308]	3	hSpCas9	negative selection	6118353
51687125	51687148	12	+	27260156	CAL120	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.3781454381459203	[881]	[1566,1590,1146]	5	hSpCas9	negative selection	6118354
51662943	51662966	12	+	27260156	CADOES1	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.18533447187801233	[703]	[598,650,411,643]	-3	hSpCas9	negative selection	6175349
51699717	51699740	12	-	27260156	CADOES1	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.5476677625785361	[528]	[585,761,709,822]	8	hSpCas9	negative selection	6175350
51662973	51662996	12	+	27260156	CADOES1	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.14874971845598972	[309]	[325,242,187,283]	-3	hSpCas9	negative selection	6175351
51687083	51687106	12	+	27260156	CADOES1	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.35313849716568835	[929]	[1021,1211,1100,1083]	6	hSpCas9	negative selection	6239603
51699691	51699714	12	-	27260156	CADOES1	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.37639408349975234	[344]	[449,433,391,388]	6	hSpCas9	negative selection	6239604
51687125	51687148	12	+	27260156	CADOES1	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.3062801079820606	[881]	[955,1013,1007,1081]	5	hSpCas9	negative selection	6239605
51662943	51662966	12	+	27260156	EWS502	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.2615866555095963	[703]	[547,636,605,708]	-4	hSpCas9	negative selection	6296600
51699717	51699740	12	-	27260156	EWS502	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.48013682876543784	[528]	[819,737,704,861]	8	hSpCas9	negative selection	6296601
51662973	51662996	12	+	27260156	EWS502	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.1918931640066387	[309]	[183,246,351,387]	-3	hSpCas9	negative selection	6296602
51687083	51687106	12	+	27260156	EWS502	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.05727380433842799	[929]	[792,1205,939,1187]	1	hSpCas9	negative selection	6360854
51699691	51699714	12	-	27260156	EWS502	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.21195583145426944	[344]	[327,480,519,368]	3	hSpCas9	negative selection	6360855
51687125	51687148	12	+	27260156	EWS502	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.22495075418183286	[881]	[1118,932,1305,1004]	4	hSpCas9	negative selection	6360856
51662943	51662966	12	+	27260156	EW8	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.1107588931581126	[703]	[701,704,368,737]	2	hSpCas9	negative selection	6417851
51699717	51699740	12	-	27260156	EW8	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.08907879997015558	[528]	[488,526,317,515]	1	hSpCas9	negative selection	6417852
51662973	51662996	12	+	27260156	EW8	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.32118876660438567	[309]	[232,238,144,199]	-5	hSpCas9	negative selection	6417853
51687083	51687106	12	+	27260156	EW8	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.05268854504964615	[929]	[903,584,852,782]	0	hSpCas9	negative selection	6482105
51699691	51699714	12	-	27260156	EW8	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.004274080826842885	[344]	[325,225,247,330]	0	hSpCas9	negative selection	6482106
51687125	51687148	12	+	27260156	EW8	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.4416693605256953	[881]	[1103,963,1026,790]	7	hSpCas9	negative selection	6482107
51662943	51662966	12	+	27260156	CORL105	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.008830973980286538	[703]	[1004,717,881,689]	0	hSpCas9	negative selection	6539102
51699717	51699740	12	-	27260156	CORL105	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.3197355335318366	[528]	[719,868,841,667]	6	hSpCas9	negative selection	6539103
51662973	51662996	12	+	27260156	CORL105	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.1336659063497554	[309]	[335,416,580,284]	2	hSpCas9	negative selection	6539104
51687083	51687106	12	+	27260156	CORL105	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.01644171051991794	[929]	[1397,803,1108,1015]	0	hSpCas9	negative selection	6603356
51699691	51699714	12	-	27260156	CORL105	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.5294252960423723	[344]	[653,598,469,592]	8	hSpCas9	negative selection	6603357
51687125	51687148	12	+	27260156	CORL105	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.3434683171002816	[881]	[1156,1169,1583,1368]	6	hSpCas9	negative selection	6603358
51662943	51662966	12	+	27260156	HS294T	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.4088540997852951	[703]	[183,396,354,556]	5	hSpCas9	negative selection	6660353
51699717	51699740	12	-	27260156	HS294T	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.22868360720575923	[528]	[258,211,260,221]	3	hSpCas9	negative selection	6660354
51662973	51662996	12	+	27260156	HS294T	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.28347247482962984	[309]	[142,189,101,146]	4	hSpCas9	negative selection	6660355
51687083	51687106	12	+	27260156	HS294T	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.3294819119923851	[929]	[336,453,603,415]	4	hSpCas9	negative selection	6724607
51699691	51699714	12	-	27260156	HS294T	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.5386207259161602	[344]	[131,226,152,281]	7	hSpCas9	negative selection	6724608
51687125	51687148	12	+	27260156	HS294T	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.45570738311842873	[881]	[533,442,366,529]	6	hSpCas9	negative selection	6724609
51662943	51662966	12	+	27260156	HCC44	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.3545936055171197	[703]	[1836,555,872,916]	6	hSpCas9	negative selection	6781604
51699717	51699740	12	-	27260156	HCC44	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.21683142563865856	[528]	[1109,446,744,559]	3	hSpCas9	negative selection	6781605
51662973	51662996	12	+	27260156	HCC44	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.14690486176584905	[309]	[391,239,309,337]	-2	hSpCas9	negative selection	6781606
51687083	51687106	12	+	27260156	HCC44	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.11117127997757748	[929]	[1114,1111,1134,1172]	1	hSpCas9	negative selection	6845858
51699691	51699714	12	-	27260156	HCC44	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.30055620969154656	[344]	[345,355,824,456]	5	hSpCas9	negative selection	6845859
51687125	51687148	12	+	27260156	HCC44	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.1344989287549555	[881]	[1238,776,1524,966]	2	hSpCas9	negative selection	6845860
51662943	51662966	12	+	27260156	G402	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.018286227934839805	[703]	[931,668,688,1168]	0	hSpCas9	negative selection	6902855
51699717	51699740	12	-	27260156	G402	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.5679516451132892	[528]	[1229,792,1006,829]	7	hSpCas9	negative selection	6902856
51662973	51662996	12	+	27260156	G402	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.08917347433147982	[309]	[335,304,498,278]	-1	hSpCas9	negative selection	6902857
51687083	51687106	12	+	27260156	G402	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.4382308187733779	[929]	[1402,2151,1415,1205]	5	hSpCas9	negative selection	6967109
51699691	51699714	12	-	27260156	G402	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.7116623440990605	[344]	[800,509,639,803]	8	hSpCas9	negative selection	6967110
51687125	51687148	12	+	27260156	G402	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.6764043549794106	[881]	[2866,1746,1058,1383]	8	hSpCas9	negative selection	6967111
51662943	51662966	12	+	27260156	L33	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.23130582324381155	[703]	[744,328,495,968]	5	hSpCas9	negative selection	7024106
51699717	51699740	12	-	27260156	L33	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.05477017963823752	[528]	[540,201,366,579]	1	hSpCas9	negative selection	7024107
51662973	51662996	12	+	27260156	L33	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.41075505278822577	[309]	[380,151,257,485]	8	hSpCas9	negative selection	7024108
51687083	51687106	12	+	27260156	L33	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.07990657422777336	[929]	[1078,325,533,790]	-2	hSpCas9	negative selection	7088360
51699691	51699714	12	-	27260156	L33	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.34701078234903604	[344]	[615,197,218,303]	7	hSpCas9	negative selection	7088361
51687125	51687148	12	+	27260156	L33	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.003203610822845704	[881]	[738,445,530,866]	0	hSpCas9	negative selection	7088362
51662943	51662966	12	+	27260156	K562	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.09388895998011798	[703]	[618,366,604,722]	-1	hSpCas9	negative selection	7145357
51699717	51699740	12	-	27260156	K562	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.7201969668883523	[528]	[740,655,699,961]	8	hSpCas9	negative selection	7145358
51662973	51662996	12	+	27260156	K562	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.24543089126509965	[309]	[152,290,361,129]	-3	hSpCas9	negative selection	7145359
51687083	51687106	12	+	27260156	K562	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.2679050535000147	[929]	[1610,735,811,863]	3	hSpCas9	negative selection	7209611
51699691	51699714	12	-	27260156	K562	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.529626880888869	[344]	[493,607,244,432]	6	hSpCas9	negative selection	7209612
51687125	51687148	12	+	27260156	K562	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.20753377858367472	[881]	[978,1144,628,879]	2	hSpCas9	negative selection	7209613
51662943	51662966	12	+	27260156	HT29	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.08054392144397826	[703]	[855,751,910,721]	-2	hSpCas9	negative selection	7266608
51699717	51699740	12	-	27260156	HT29	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.20098497651898403	[528]	[817,855,711,598]	4	hSpCas9	negative selection	7266609
51662973	51662996	12	+	27260156	HT29	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.09354066793157678	[309]	[376,401,434,218]	-2	hSpCas9	negative selection	7266610
51687083	51687106	12	+	27260156	HT29	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.04433984657752266	[929]	[1232,1306,1387,790]	0	hSpCas9	negative selection	7330862
51699691	51699714	12	-	27260156	HT29	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.1968622642346246	[344]	[374,469,653,418]	4	hSpCas9	negative selection	7330863
51687125	51687148	12	+	27260156	HT29	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.1655392279666298	[881]	[1298,1466,1181,918]	3	hSpCas9	negative selection	7330864
51662943	51662966	12	+	27260156	MHHES1	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.11987389995141273	[703]	[1107,933,798,667]	2	hSpCas9	negative selection	7387859
51699717	51699740	12	-	27260156	MHHES1	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.08041568186801376	[528]	[531,911,559,538]	1	hSpCas9	negative selection	7387860
51662973	51662996	12	+	27260156	MHHES1	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.24187341102324467	[309]	[343,192,322,306]	-4	hSpCas9	negative selection	7387861
51687083	51687106	12	+	27260156	MHHES1	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.040340309612887815	[929]	[1092,1171,792,1015]	0	hSpCas9	negative selection	7452113
51699691	51699714	12	-	27260156	MHHES1	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.47847301145600646	[344]	[643,490,504,523]	8	hSpCas9	negative selection	7452114
51687125	51687148	12	+	27260156	MHHES1	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.13589747392067275	[881]	[1425,996,1048,935]	2	hSpCas9	negative selection	7452115
51662943	51662966	12	+	27260156	MEWO	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.01984831717755342	[703]	[917,587,545]	0	hSpCas9	negative selection	7509110
51699717	51699740	12	-	27260156	MEWO	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	-0.18293119939763378	[528]	[435,400,470]	-4	hSpCas9	negative selection	7509111
51662973	51662996	12	+	27260156	MEWO	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.06500845084176243	[309]	[258,305,262]	-1	hSpCas9	negative selection	7509112
51687083	51687106	12	+	27260156	MEWO	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.16838199467496173	[929]	[856,679,801]	-4	hSpCas9	negative selection	7573364
51699691	51699714	12	-	27260156	MEWO	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.5121607930178138	[344]	[540,359,495]	9	hSpCas9	negative selection	7573365
51687125	51687148	12	+	27260156	MEWO	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	-0.06736152904841597	[881]	[925,627,835]	-1	hSpCas9	negative selection	7573366
51662943	51662966	12	+	27260156	LNCAPCLONEFGC	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.020591150108997036	[703]	[549,612,797,580]	0	hSpCas9	negative selection	7630361
51699717	51699740	12	-	27260156	LNCAPCLONEFGC	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.34340336436583696	[528]	[837,490,649,461]	5	hSpCas9	negative selection	7630362
51662973	51662996	12	+	27260156	LNCAPCLONEFGC	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.29622816987600276	[309]	[220,286,161,230]	-4	hSpCas9	negative selection	7630363
51687083	51687106	12	+	27260156	LNCAPCLONEFGC	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.19488880218987137	[929]	[889,845,958,1169]	3	hSpCas9	negative selection	7694615
51699691	51699714	12	-	27260156	LNCAPCLONEFGC	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.10777533815513057	[344]	[340,234,427,362]	1	hSpCas9	negative selection	7694616
51687125	51687148	12	+	27260156	LNCAPCLONEFGC	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.21775365668170188	[881]	[729,1032,1131,847]	3	hSpCas9	negative selection	7694617
51662943	51662966	12	+	27260156	PANC0327	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.01942772789294267	[703]	[572,458,416,1034]	0	hSpCas9	negative selection	7751612
51699717	51699740	12	-	27260156	PANC0327	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.12385326244166187	[528]	[581,424,532,524]	1	hSpCas9	negative selection	7751613
51662973	51662996	12	+	27260156	PANC0327	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.8412216733059881	[309]	[568,185,509,753]	9	hSpCas9	negative selection	7751614
51687083	51687106	12	+	27260156	PANC0327	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.14160664376859156	[929]	[696,731,655,907]	-2	hSpCas9	negative selection	7815866
51699691	51699714	12	-	27260156	PANC0327	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	-0.06051308848811582	[344]	[467,131,470,139]	-1	hSpCas9	negative selection	7815867
51687125	51687148	12	+	27260156	PANC0327	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.3550390892317067	[881]	[1301,950,825,959]	5	hSpCas9	negative selection	7815868
51662943	51662966	12	+	27260156	NCIH2009	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.03884869465931873	[703]	[1196,706,1167]	0	hSpCas9	negative selection	7872863
51699717	51699740	12	-	27260156	NCIH2009	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.40726165034230966	[528]	[1038,784,1129]	5	hSpCas9	negative selection	7872864
51662973	51662996	12	+	27260156	NCIH2009	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.50440433079915	[309]	[750,456,663]	7	hSpCas9	negative selection	7872865
51687083	51687106	12	+	27260156	NCIH2009	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.24218845288546986	[929]	[2236,1225,1288]	3	hSpCas9	negative selection	7937117
51699691	51699714	12	-	27260156	NCIH2009	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.5179345535003422	[344]	[543,609,887]	7	hSpCas9	negative selection	7937118
51687125	51687148	12	+	27260156	NCIH2009	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.38669154151095186	[881]	[2260,1224,1479]	5	hSpCas9	negative selection	7937119
51662943	51662966	12	+	27260156	NCIH1373	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.9831427384166067	[703]	[522,283,380,115]	-7	hSpCas9	negative selection	7994114
51699717	51699740	12	-	27260156	NCIH1373	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.9564833314986445	[528]	[1479,1211,869,283]	8	hSpCas9	negative selection	7994115
51662973	51662996	12	+	27260156	NCIH1373	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.40232613645414356	[309]	[377,458,536,116]	4	hSpCas9	negative selection	7994116
51687083	51687106	12	+	27260156	NCIH1373	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.5980859947265931	[929]	[1694,1813,1515,328]	6	hSpCas9	negative selection	8058368
51699691	51699714	12	-	27260156	NCIH1373	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.22328118695853258	[344]	[255,585,532,98]	2	hSpCas9	negative selection	8058369
51687125	51687148	12	+	27260156	NCIH1373	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.3578981171415524	[881]	[1044,1159,1072,471]	3	hSpCas9	negative selection	8058370
51662943	51662966	12	+	27260156	PATU8902	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.2067994979817973	[703]	[833,782,1541,1270]	2	hSpCas9	negative selection	8115365
51699717	51699740	12	-	27260156	PATU8902	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.5388057912979022	[528]	[644,1000,728,2116]	5	hSpCas9	negative selection	8115366
51662973	51662996	12	+	27260156	PATU8902	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.01822679533804361	[309]	[372,688,198,562]	0	hSpCas9	negative selection	8115367
51687083	51687106	12	+	27260156	PATU8902	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.2396229416120308	[929]	[1702,1134,2001,1084]	2	hSpCas9	negative selection	8179619
51699691	51699714	12	-	27260156	PATU8902	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.2505916780104981	[344]	[497,490,638,645]	2	hSpCas9	negative selection	8179620
51687125	51687148	12	+	27260156	PATU8902	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.4930895420122178	[881]	[1872,1160,1656,2292]	5	hSpCas9	negative selection	8179621
51662943	51662966	12	+	27260156	PANC1	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.1086613108261919	[703]	[652,725,735,519]	1	hSpCas9	negative selection	8236616
51699717	51699740	12	-	27260156	PANC1	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.49218847579615754	[528]	[716,962,522,439]	7	hSpCas9	negative selection	8236617
51662973	51662996	12	+	27260156	PANC1	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.05734704788200973	[309]	[208,343,267,222]	-1	hSpCas9	negative selection	8236618
51687083	51687106	12	+	27260156	PANC1	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.21628529347500014	[929]	[890,1002,1060,782]	3	hSpCas9	negative selection	8300870
51699691	51699714	12	-	27260156	PANC1	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.4443901650837962	[344]	[398,580,525,175]	7	hSpCas9	negative selection	8300871
51687125	51687148	12	+	27260156	PANC1	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.38497632911296076	[881]	[960,1454,934,728]	6	hSpCas9	negative selection	8300872
51662943	51662966	12	+	27260156	PANC0813	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.146997196659712	[703]	[1116,758,773,1022]	2	hSpCas9	negative selection	8357867
51699717	51699740	12	-	27260156	PANC0813	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.6703603033483151	[528]	[782,1011,1035,1097]	9	hSpCas9	negative selection	8357868
51662973	51662996	12	+	27260156	PANC0813	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.16141441644410087	[309]	[482,457,325,369]	2	hSpCas9	negative selection	8357869
51687083	51687106	12	+	27260156	PANC0813	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.08513854906626461	[929]	[1309,946,1457,945]	1	hSpCas9	negative selection	8422121
51699691	51699714	12	-	27260156	PANC0813	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.5307476366734037	[344]	[861,547,465,494]	8	hSpCas9	negative selection	8422122
51687125	51687148	12	+	27260156	PANC0813	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.012484302351099874	[881]	[1279,1046,962,916]	0	hSpCas9	negative selection	8422123
51662943	51662966	12	+	27260156	RDES	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.6129631701264624	[703]	[482,477,489,686]	-8	hSpCas9	negative selection	8479118
51699717	51699740	12	-	27260156	RDES	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.20587655940921593	[528]	[579,567,822,886]	3	hSpCas9	negative selection	8479119
51662973	51662996	12	+	27260156	RDES	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.055566511997021895	[309]	[265,374,426,437]	0	hSpCas9	negative selection	8479120
51687083	51687106	12	+	27260156	RDES	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.12158219864022324	[929]	[1069,999,1214,1406]	2	hSpCas9	negative selection	8543372
51699691	51699714	12	-	27260156	RDES	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.24356182141253646	[344]	[464,450,493,453]	4	hSpCas9	negative selection	8543373
51687125	51687148	12	+	27260156	RDES	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.1902443850934198	[881]	[1055,939,1384,1281]	3	hSpCas9	negative selection	8543374
51662943	51662966	12	+	27260156	PC3	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.160678684111851	[703]	[296,774,1047,642]	-4	hSpCas9	negative selection	8600369
51699717	51699740	12	-	27260156	PC3	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	-0.10155861802860701	[528]	[310,501,751,533]	-2	hSpCas9	negative selection	8600370
51662973	51662996	12	+	27260156	PC3	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.16016968461251635	[309]	[203,188,428,352]	-4	hSpCas9	negative selection	8600371
51687083	51687106	12	+	27260156	PC3	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.00503576027585928	[929]	[740,846,1294,955]	0	hSpCas9	negative selection	8664623
51699691	51699714	12	-	27260156	PC3	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.06579827888922729	[344]	[227,251,612,479]	1	hSpCas9	negative selection	8664624
51687125	51687148	12	+	27260156	PC3	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	-0.17124838873614678	[881]	[465,780,1439,756]	-4	hSpCas9	negative selection	8664625
51662943	51662966	12	+	27260156	PATU8988T	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.03763289202876585	[703]	[744,469,614,963]	0	hSpCas9	negative selection	8721620
51699717	51699740	12	-	27260156	PATU8988T	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.21639506129539385	[528]	[472,654,582,676]	4	hSpCas9	negative selection	8721621
51662973	51662996	12	+	27260156	PATU8988T	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.46821327354856246	[309]	[140,346,143,249]	-6	hSpCas9	negative selection	8721622
51687083	51687106	12	+	27260156	PATU8988T	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.008613177000636574	[929]	[650,1149,999,785]	0	hSpCas9	negative selection	8785874
51699691	51699714	12	-	27260156	PATU8988T	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.505684022245809	[344]	[538,506,384,465]	8	hSpCas9	negative selection	8785875
51687125	51687148	12	+	27260156	PATU8988T	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.014551459905051134	[881]	[776,841,699,1147]	0	hSpCas9	negative selection	8785876
51662943	51662966	12	+	27260156	T47D	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.11062286614436767	[703]	[820,604,788,838]	-2	hSpCas9	negative selection	8842871
51699717	51699740	12	-	27260156	T47D	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.15444463823667307	[528]	[728,742,627,637]	3	hSpCas9	negative selection	8842872
51662973	51662996	12	+	27260156	T47D	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.14036048786033106	[309]	[287,348,348,321]	-3	hSpCas9	negative selection	8842873
51687083	51687106	12	+	27260156	T47D	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.020206559930739165	[929]	[963,1109,1107,1086]	0	hSpCas9	negative selection	8907125
51699691	51699714	12	-	27260156	T47D	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.3280316670298936	[344]	[656,483,465,410]	7	hSpCas9	negative selection	8907126
51687125	51687148	12	+	27260156	T47D	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.15784807932184963	[881]	[1111,1112,1185,1176]	3	hSpCas9	negative selection	8907127
51662943	51662966	12	+	27260156	SU8686	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.05643259340617124	[703]	[621,818,628,843]	0	hSpCas9	negative selection	8964122
51699717	51699740	12	-	27260156	SU8686	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.3383994263098624	[528]	[626,681,549,810]	6	hSpCas9	negative selection	8964123
51662973	51662996	12	+	27260156	SU8686	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.04869250021153082	[309]	[406,269,228,263]	-1	hSpCas9	negative selection	8964124
51687083	51687106	12	+	27260156	SU8686	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.07690358525126917	[929]	[801,870,847,996]	-1	hSpCas9	negative selection	9028376
51699691	51699714	12	-	27260156	SU8686	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.1977491950890971	[344]	[398,387,397,378]	3	hSpCas9	negative selection	9028377
51687125	51687148	12	+	27260156	SU8686	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.39703702240966254	[881]	[1125,989,1203,1331]	6	hSpCas9	negative selection	9028378
51662943	51662966	12	+	27260156	SKES1	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.15253487368964053	[703]	[741,615,596,584]	-3	hSpCas9	negative selection	9085373
51699717	51699740	12	-	27260156	SKES1	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.12468949619989914	[528]	[835,698,502,337]	2	hSpCas9	negative selection	9085374
51662973	51662996	12	+	27260156	SKES1	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.0833022461481302	[309]	[282,318,358,213]	-2	hSpCas9	negative selection	9085375
51687083	51687106	12	+	27260156	SKES1	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.046125249248441635	[929]	[1086,1107,717,743]	-1	hSpCas9	negative selection	9149627
51699691	51699714	12	-	27260156	SKES1	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.09029761368533501	[344]	[549,426,296,236]	2	hSpCas9	negative selection	9149628
51687125	51687148	12	+	27260156	SKES1	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.03055308609875218	[881]	[934,888,935,835]	0	hSpCas9	negative selection	9149629
51662943	51662966	12	+	27260156	TOV112D	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	0.07056384696104956	[703]	[846,1210,529,503]	1	hSpCas9	negative selection	9206624
51699717	51699740	12	-	27260156	TOV112D	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.06550870616269697	[528]	[694,649,527,383]	1	hSpCas9	negative selection	9206625
51662973	51662996	12	+	27260156	TOV112D	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.06691559888353238	[309]	[272,427,197,315]	-1	hSpCas9	negative selection	9206626
51687083	51687106	12	+	27260156	TOV112D	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.06777125481314172	[929]	[1002,1577,833,647]	1	hSpCas9	negative selection	9270878
51699691	51699714	12	-	27260156	TOV112D	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.06593422965877249	[344]	[397,600,287,224]	1	hSpCas9	negative selection	9270879
51687125	51687148	12	+	27260156	TOV112D	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.13016576972696592	[881]	[774,1754,715,801]	2	hSpCas9	negative selection	9270880
51662943	51662966	12	+	27260156	TC71	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.04610513486134271	[703]	[819,673,614,821]	-1	hSpCas9	negative selection	9327875
51699717	51699740	12	-	27260156	TC71	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.04832859664005687	[528]	[399,726,614,607]	1	hSpCas9	negative selection	9327876
51662973	51662996	12	+	27260156	TC71	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.06765233707021312	[309]	[376,302,245,344]	-2	hSpCas9	negative selection	9327877
51687083	51687106	12	+	27260156	TC71	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	-0.01666350841469444	[929]	[1064,1011,854,1013]	0	hSpCas9	negative selection	9392129
51699691	51699714	12	-	27260156	TC71	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.2167215421828931	[344]	[339,510,406,465]	5	hSpCas9	negative selection	9392130
51687125	51687148	12	+	27260156	TC71	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	-0.05262142084926569	[881]	[1042,923,838,834]	-1	hSpCas9	negative selection	9392131
51662943	51662966	12	+	27260156	TC32	viability	CAGTCATCGGGAGGACGATGAGG	SCN8A	ENSG00000196876	-0.15109758739889684	[703]	[513,521,684,683]	-3	hSpCas9	negative selection	9449126
51699717	51699740	12	-	27260156	TC32	viability	ATAGCTCTCGTTGAAGTTTATGG	SCN8A	ENSG00000196876	0.13776741012953966	[528]	[562,420,707,534]	2	hSpCas9	negative selection	9449127
51662973	51662996	12	+	27260156	TC32	viability	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-0.08263115639120178	[309]	[251,238,368,254]	-1	hSpCas9	negative selection	9449128
51687083	51687106	12	+	27260156	TC32	viability	TTTGACAGGTACACGTTCACAGG	SCN8A	ENSG00000196876	0.10733806435544024	[929]	[911,556,1432,1051]	2	hSpCas9	negative selection	9513380
51699691	51699714	12	-	27260156	TC32	viability	ACACAACACACTTGTTTCGAAGG	SCN8A	ENSG00000196876	0.010266220231392231	[344]	[311,215,455,371]	0	hSpCas9	negative selection	9513381
51687125	51687148	12	+	27260156	TC32	viability	CTAGTGAAAATCATTGCAAGAGG	SCN8A	ENSG00000196876	0.2830391575010077	[881]	[978,670,1447,1089]	5	hSpCas9	negative selection	9513382
51662973	51662996	12	+	27869803	HPAFII	viability after 27 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	1.204581971865393	[270]	[557,136,NaN]	8	hSpCas9	negative selection	9547169
51702765	51702788	12	+	27869803	HPAFII	viability after 27 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-0.9768834038382748	[80]	[25,17,NaN]	-6	hSpCas9	negative selection	9547171
51705590	51705613	12	+	27869803	HPAFII	viability after 27 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	0.005254221920526603	[188]	[132,71,NaN]	0	hSpCas9	negative selection	9547172
51706526	51706549	12	+	27869803	HPAFII	viability after 27 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	0.6356055815899692	[194]	[269,66,NaN]	5	hSpCas9	negative selection	9547173
51721659	51721682	12	+	27869803	HPAFII	viability after 27 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.07653315227834967	[834]	[379,531,NaN]	0	hSpCas9	negative selection	9547175
51745961	51745984	12	+	27869803	HPAFII	viability after 27 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.5044930486411321	[221]	[48,109,NaN]	-4	hSpCas9	negative selection	9547176
51662973	51662996	12	+	27869803	HPAFII	viability after 15 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.9585349177238425	[270]	[914,348,NaN]	9	hSpCas9	negative selection	9629618
51702765	51702788	12	+	27869803	HPAFII	viability after 15 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-0.427350646486369	[80]	[81,53,NaN]	-5	hSpCas9	negative selection	9629620
51705590	51705613	12	+	27869803	HPAFII	viability after 15 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	0.11273109198205233	[188]	[210,224,NaN]	1	hSpCas9	negative selection	9629621
51706526	51706549	12	+	27869803	HPAFII	viability after 15 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	0.6230674036811734	[194]	[553,178,NaN]	7	hSpCas9	negative selection	9629622
51721659	51721682	12	+	27869803	HPAFII	viability after 15 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.14239877361846398	[834]	[1283,807,NaN]	1	hSpCas9	negative selection	9629624
51745961	51745984	12	+	27869803	HPAFII	viability after 15 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	0.3754466267318292	[221]	[401,251,NaN]	4	hSpCas9	negative selection	9629625
51662973	51662996	12	+	27869803	ASPC1	viability after 36 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	-1.3466119476052592	[692]	[67,54,144]	-8	hSpCas9	negative selection	9712067
51702765	51702788	12	+	27869803	ASPC1	viability after 36 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	0.5993564592533751	[228]	[103,67,173]	6	hSpCas9	negative selection	9712069
51705590	51705613	12	+	27869803	ASPC1	viability after 36 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.35033084620985855	[365]	[146,48,106]	-4	hSpCas9	negative selection	9712070
51706526	51706549	12	+	27869803	ASPC1	viability after 36 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.6969141439536133	[479]	[125,186,19]	-6	hSpCas9	negative selection	9712071
51721659	51721682	12	+	27869803	ASPC1	viability after 36 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	-0.06902170165513843	[2225]	[537,386,1155]	0	hSpCas9	negative selection	9712073
51745961	51745984	12	+	27869803	ASPC1	viability after 36 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	1.2021612060042395	[600]	[679,356,438]	9	hSpCas9	negative selection	9712074
51662973	51662996	12	+	27869803	PATU8988S	viability after 35 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.5659311033395551	[411]	[305,184,NaN]	6	hSpCas9	negative selection	9794516
51702765	51702788	12	+	27869803	PATU8988S	viability after 35 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-0.2777109035982772	[190]	[43,82,NaN]	-3	hSpCas9	negative selection	9794518
51705590	51705613	12	+	27869803	PATU8988S	viability after 35 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	-0.28926620261032465	[351]	[120,110,NaN]	-3	hSpCas9	negative selection	9794519
51706526	51706549	12	+	27869803	PATU8988S	viability after 35 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.3834179499493851	[409]	[165,86,NaN]	-4	hSpCas9	negative selection	9794520
51721659	51721682	12	+	27869803	PATU8988S	viability after 35 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.3907794905323081	[1646]	[953,784,NaN]	4	hSpCas9	negative selection	9794522
51745961	51745984	12	+	27869803	PATU8988S	viability after 35 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.0025099801903639904	[525]	[201,220,NaN]	0	hSpCas9	negative selection	9794523
51662973	51662996	12	+	27869803	PATU8988S	viability after 31 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	0.8286255900484922	[411]	[311,265,NaN]	8	hSpCas9	negative selection	9876965
51702765	51702788	12	+	27869803	PATU8988S	viability after 31 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-0.3202779298119167	[190]	[49,74,NaN]	-4	hSpCas9	negative selection	9876967
51705590	51705613	12	+	27869803	PATU8988S	viability after 31 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	0.11724266747640555	[351]	[153,149,NaN]	1	hSpCas9	negative selection	9876968
51706526	51706549	12	+	27869803	PATU8988S	viability after 31 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	-0.1357338249162558	[409]	[172,117,NaN]	-1	hSpCas9	negative selection	9876969
51721659	51721682	12	+	27869803	PATU8988S	viability after 31 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.5248120714567139	[1646]	[888,1015,NaN]	6	hSpCas9	negative selection	9876971
51745961	51745984	12	+	27869803	PATU8988S	viability after 31 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.31368387338668413	[525]	[133,212,NaN]	-4	hSpCas9	negative selection	9876972
51662973	51662996	12	+	27869803	HPAFII	viability after 35 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	1.590337834786873	[270]	[644,151,NaN]	9	hSpCas9	negative selection	9959414
51702765	51702788	12	+	27869803	HPAFII	viability after 35 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-1.2018433064395162	[80]	[22,11,NaN]	-6	hSpCas9	negative selection	9959416
51705590	51705613	12	+	27869803	HPAFII	viability after 35 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	0.2718666852090962	[188]	[99,132,NaN]	1	hSpCas9	negative selection	9959417
51706526	51706549	12	+	27869803	HPAFII	viability after 35 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	0.8257412389687293	[194]	[237,103,NaN]	5	hSpCas9	negative selection	9959418
51721659	51721682	12	+	27869803	HPAFII	viability after 35 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.3831613346050171	[834]	[214,929,NaN]	2	hSpCas9	negative selection	9959420
51745961	51745984	12	+	27869803	HPAFII	viability after 35 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.6556896013030872	[221]	[44,100,NaN]	-4	hSpCas9	negative selection	9959421
51662973	51662996	12	+	27869803	HPAFII	viability after 31 days	GCCCAAGCCAAACAGCGACCTGG	SCN8A	ENSG00000196876	1.1301053069750546	[270]	[508,140,NaN]	8	hSpCas9	negative selection	10041863
51702765	51702788	12	+	27869803	HPAFII	viability after 31 days	TTCTTTAGGCAATGCCCAGAGGG	SCN8A	ENSG00000196876	-0.6545513318826388	[80]	[14,43,NaN]	-4	hSpCas9	negative selection	10041865
51705590	51705613	12	+	27869803	HPAFII	viability after 31 days	GGAGCAACTTAAGAAGCAACAGG	SCN8A	ENSG00000196876	0.6277379448088535	[188]	[127,202,NaN]	4	hSpCas9	negative selection	10041866
51706526	51706549	12	+	27869803	HPAFII	viability after 31 days	ACTCAGCTCAAAGAGTGCAAAGG	SCN8A	ENSG00000196876	0.8056800802941277	[194]	[275,98,NaN]	6	hSpCas9	negative selection	10041867
51721659	51721682	12	+	27869803	HPAFII	viability after 31 days	CGCGGATGACGAGCACAGCACGG	SCN8A	ENSG00000196876	0.03327624692815734	[834]	[301,672,NaN]	0	hSpCas9	negative selection	10041869
51745961	51745984	12	+	27869803	HPAFII	viability after 31 days	ACCAATTAGCCTCCTACGGGCGG	SCN8A	ENSG00000196876	-0.5563896555504938	[221]	[44,127,NaN]	-4	hSpCas9	negative selection	10041870
51721662	51721685	12	+	28162770	P31FUJ	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	0.3668818020135433	[129]	[196]	4	hSpCas9	negative selection	10230718
51721818	51721841	12	+	28162770	P31FUJ	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.4510136832330629	[93]	[150]	5	hSpCas9	negative selection	10230719
51769122	51769145	12	-	28162770	P31FUJ	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.3418919608529505	[140]	[209]	4	hSpCas9	negative selection	10230720
51662807	51662830	12	+	28162770	P31FUJ	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.9531707382598036	[148]	[338]	9	hSpCas9	negative selection	10230721
51702856	51702879	12	-	28162770	P31FUJ	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	0.5834858424132332	[91]	[161]	6	hSpCas9	negative selection	10230722
51705533	51705556	12	+	28162770	P31FUJ	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	0.45685767497347074	[30]	[49]	5	hSpCas9	negative selection	10230723
51706552	51706575	12	+	28162770	P31FUJ	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-1.3821798284526052	[121]	[54]	-7	hSpCas9	negative selection	10230724
51706601	51706624	12	+	28162770	P31FUJ	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	-0.3379457084387132	[312]	[290]	-3	hSpCas9	negative selection	10230725
51721675	51721698	12	+	28162770	P31FUJ	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	-0.08984425057233567	[191]	[211]	-1	hSpCas9	negative selection	10230726
51721698	51721721	12	-	28162770	P31FUJ	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	0.08912589047298436	[7]	[9]	0	hSpCas9	negative selection	10230727
51721662	51721685	12	+	28162770	TF1	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10400084
51721818	51721841	12	+	28162770	TF1	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10400085
51769122	51769145	12	-	28162770	TF1	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10400086
51662807	51662830	12	+	28162770	TF1	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	NaN	[NaN]	[231]	1	hSpCas9	negative selection	10400087
51702856	51702879	12	-	28162770	TF1	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10400088
51705533	51705556	12	+	28162770	TF1	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10400089
51706552	51706575	12	+	28162770	TF1	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10400090
51706601	51706624	12	+	28162770	TF1	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10400091
51721675	51721698	12	+	28162770	TF1	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	NaN	[NaN]	[162]	1	hSpCas9	negative selection	10400092
51721698	51721721	12	-	28162770	TF1	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10400093
51721662	51721685	12	+	28162770	SKM1	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	1.1572397418111973	[34]	[137]	9	hSpCas9	negative selection	10569450
51721818	51721841	12	+	28162770	SKM1	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.07490480901389063	[28]	[53]	0	hSpCas9	negative selection	10569451
51769122	51769145	12	-	28162770	SKM1	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.9269365378102767	[35]	[120]	8	hSpCas9	negative selection	10569452
51662807	51662830	12	+	28162770	SKM1	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.0492649878557917	[81]	[149]	0	hSpCas9	negative selection	10569453
51702856	51702879	12	-	28162770	SKM1	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	0.34238511987887676	[28]	[64]	3	hSpCas9	negative selection	10569454
51705533	51705556	12	+	28162770	SKM1	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	-0.06711419585853706	[15]	[26]	0	hSpCas9	negative selection	10569455
51706552	51706575	12	+	28162770	SKM1	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-0.23703919730084966	[17]	[26]	-2	hSpCas9	negative selection	10569456
51706601	51706624	12	+	28162770	SKM1	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	0.29693937470150195	[63]	[138]	3	hSpCas9	negative selection	10569457
51721675	51721698	12	+	28162770	SKM1	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	-0.5418937788292703	[55]	[67]	-4	hSpCas9	negative selection	10569458
51721698	51721721	12	-	28162770	SKM1	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-2.406964198743162	[2]	[0]	-8	hSpCas9	negative selection	10569459
51721662	51721685	12	+	28162770	SKM1	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	1.1572397418111973	[34]	[137]	9	hSpCas9	negative selection	10738816
51721818	51721841	12	+	28162770	SKM1	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.07490480901389063	[28]	[53]	0	hSpCas9	negative selection	10738817
51769122	51769145	12	-	28162770	SKM1	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.9269365378102767	[35]	[120]	8	hSpCas9	negative selection	10738818
51662807	51662830	12	+	28162770	SKM1	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.0492649878557917	[81]	[149]	0	hSpCas9	negative selection	10738819
51702856	51702879	12	-	28162770	SKM1	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	0.34238511987887676	[28]	[64]	3	hSpCas9	negative selection	10738820
51705533	51705556	12	+	28162770	SKM1	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	-0.06711419585853706	[15]	[26]	0	hSpCas9	negative selection	10738821
51706552	51706575	12	+	28162770	SKM1	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-0.23703919730084966	[17]	[26]	-2	hSpCas9	negative selection	10738822
51706601	51706624	12	+	28162770	SKM1	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	0.29693937470150195	[63]	[138]	3	hSpCas9	negative selection	10738823
51721675	51721698	12	+	28162770	SKM1	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	-0.5418937788292703	[55]	[67]	-4	hSpCas9	negative selection	10738824
51721698	51721721	12	-	28162770	SKM1	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-2.406964198743162	[2]	[0]	-8	hSpCas9	negative selection	10738825
51721662	51721685	12	+	28162770	PL21	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	0.15831943879469304	[174]	[84]	1	hSpCas9	negative selection	10908182
51721818	51721841	12	+	28162770	PL21	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.29324901888080146	[74]	[39]	2	hSpCas9	negative selection	10908183
51769122	51769145	12	-	28162770	PL21	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.08278266385116129	[127]	[58]	0	hSpCas9	negative selection	10908184
51662807	51662830	12	+	28162770	PL21	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.3521427079343701	[188]	[104]	3	hSpCas9	negative selection	10908185
51702856	51702879	12	-	28162770	PL21	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	1.096516983415163	[100]	[93]	8	hSpCas9	negative selection	10908186
51705533	51705556	12	+	28162770	PL21	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	-0.23595950031735313	[45]	[16]	-2	hSpCas9	negative selection	10908187
51706552	51706575	12	+	28162770	PL21	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-1.577467964174232	[47]	[6]	-7	hSpCas9	negative selection	10908188
51706601	51706624	12	+	28162770	PL21	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	1.0917634534445282	[151]	[140]	8	hSpCas9	negative selection	10908189
51721675	51721698	12	+	28162770	PL21	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	1.5220677093766826	[107]	[134]	9	hSpCas9	negative selection	10908190
51721698	51721721	12	-	28162770	PL21	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	0.20013961448931994	[5]	[2]	1	hSpCas9	negative selection	10908191
51721662	51721685	12	+	28162770	P31FUJ	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	0.3668818020135433	[129]	[196]	4	hSpCas9	negative selection	11077548
51721818	51721841	12	+	28162770	P31FUJ	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.4510136832330629	[93]	[150]	5	hSpCas9	negative selection	11077549
51769122	51769145	12	-	28162770	P31FUJ	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.3418919608529505	[140]	[209]	4	hSpCas9	negative selection	11077550
51662807	51662830	12	+	28162770	P31FUJ	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.9531707382598036	[148]	[338]	9	hSpCas9	negative selection	11077551
51702856	51702879	12	-	28162770	P31FUJ	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	0.5834858424132332	[91]	[161]	6	hSpCas9	negative selection	11077552
51705533	51705556	12	+	28162770	P31FUJ	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	0.45685767497347074	[30]	[49]	5	hSpCas9	negative selection	11077553
51706552	51706575	12	+	28162770	P31FUJ	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-1.3821798284526052	[121]	[54]	-7	hSpCas9	negative selection	11077554
51706601	51706624	12	+	28162770	P31FUJ	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	-0.3379457084387132	[312]	[290]	-3	hSpCas9	negative selection	11077555
51721675	51721698	12	+	28162770	P31FUJ	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	-0.08984425057233567	[191]	[211]	-1	hSpCas9	negative selection	11077556
51721698	51721721	12	-	28162770	P31FUJ	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	0.08912589047298436	[7]	[9]	0	hSpCas9	negative selection	11077557
51721662	51721685	12	+	28162770	OCIAML5	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	2.062203555110119	[25]	[195]	9	hSpCas9	negative selection	11246914
51721818	51721841	12	+	28162770	OCIAML5	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.05125740972432924	[53]	[100]	0	hSpCas9	negative selection	11246915
51769122	51769145	12	-	28162770	OCIAML5	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	-0.004069664309046872	[69]	[125]	0	hSpCas9	negative selection	11246916
51662807	51662830	12	+	28162770	OCIAML5	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.8100048555549255	[84]	[268]	7	hSpCas9	negative selection	11246917
51702856	51702879	12	-	28162770	OCIAML5	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	0.8710932237771786	[62]	[207]	7	hSpCas9	negative selection	11246918
51705533	51705556	12	+	28162770	OCIAML5	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	2.0497530351970994	[18]	[141]	9	hSpCas9	negative selection	11246919
51706552	51706575	12	+	28162770	OCIAML5	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	0.9828741828655065	[36]	[131]	8	hSpCas9	negative selection	11246920
51706601	51706624	12	+	28162770	OCIAML5	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	-0.892424308480138	[144]	[140]	-5	hSpCas9	negative selection	11246921
51721675	51721698	12	+	28162770	OCIAML5	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	-0.6846098250124342	[129]	[145]	-4	hSpCas9	negative selection	11246922
51721698	51721721	12	-	28162770	OCIAML5	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	0.780201644635516	[9]	[30]	6	hSpCas9	negative selection	11246923
51721662	51721685	12	+	28162770	EOL1	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	0.16036070866930424	[213]	[125]	1	hSpCas9	negative selection	11416280
51721818	51721841	12	+	28162770	EOL1	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.7252389633471279	[92]	[80]	6	hSpCas9	negative selection	11416281
51769122	51769145	12	-	28162770	EOL1	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.6119575412625082	[230]	[185]	5	hSpCas9	negative selection	11416282
51662807	51662830	12	+	28162770	EOL1	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.11551821782067628	[430]	[245]	1	hSpCas9	negative selection	11416283
51702856	51702879	12	-	28162770	EOL1	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	0.3799647323652177	[228]	[156]	3	hSpCas9	negative selection	11416284
51705533	51705556	12	+	28162770	EOL1	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	0.9104725863588116	[102]	[101]	7	hSpCas9	negative selection	11416285
51706552	51706575	12	+	28162770	EOL1	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-1.6115051286696755	[57]	[9]	-7	hSpCas9	negative selection	11416286
51706601	51706624	12	+	28162770	EOL1	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	-1.192809179067624	[255]	[58]	-7	hSpCas9	negative selection	11416287
51721675	51721698	12	+	28162770	EOL1	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	0.708229864643771	[157]	[135]	6	hSpCas9	negative selection	11416288
51721698	51721721	12	-	28162770	EOL1	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-1.8828071504870696	[6]	[0]	-8	hSpCas9	negative selection	11416289
51721662	51721685	12	+	28162770	MOLM13	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	-1.2325503365965134	[181]	[55]	-6	hSpCas9	negative selection	11585646
51721818	51721841	12	+	28162770	MOLM13	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	-0.43354678397183166	[98]	[52]	-3	hSpCas9	negative selection	11585647
51769122	51769145	12	-	28162770	MOLM13	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.5343847933314856	[211]	[221]	4	hSpCas9	negative selection	11585648
51662807	51662830	12	+	28162770	MOLM13	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.7301860246208534	[325]	[390]	5	hSpCas9	negative selection	11585649
51702856	51702879	12	-	28162770	MOLM13	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	1.4134415975222026	[188]	[363]	9	hSpCas9	negative selection	11585650
51705533	51705556	12	+	28162770	MOLM13	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	0.7073553162399682	[71]	[84]	5	hSpCas9	negative selection	11585651
51706552	51706575	12	+	28162770	MOLM13	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-4.454942757932961	[90]	[2]	-9	hSpCas9	negative selection	11585652
51706601	51706624	12	+	28162770	MOLM13	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	-3.1532069052302907	[282]	[22]	-8	hSpCas9	negative selection	11585653
51721675	51721698	12	+	28162770	MOLM13	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	-0.4887180229420405	[261]	[134]	-3	hSpCas9	negative selection	11585654
51721698	51721721	12	-	28162770	MOLM13	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-4.576504737813875	[32]	[0]	-9	hSpCas9	negative selection	11585655
51721662	51721685	12	+	28162770	HEL	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	1.2439663870842974	[146]	[222]	9	hSpCas9	negative selection	11755012
51721818	51721841	12	+	28162770	HEL	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.512342194744682	[80]	[73]	4	hSpCas9	negative selection	11755013
51769122	51769145	12	-	28162770	HEL	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.48046740310148006	[187]	[167]	4	hSpCas9	negative selection	11755014
51662807	51662830	12	+	28162770	HEL	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.698954841566905	[301]	[313]	6	hSpCas9	negative selection	11755015
51702856	51702879	12	-	28162770	HEL	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	0.9278960487322907	[150]	[183]	7	hSpCas9	negative selection	11755016
51705533	51705556	12	+	28162770	HEL	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	0.20884230547019733	[76]	[56]	1	hSpCas9	negative selection	11755017
51706552	51706575	12	+	28162770	HEL	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-0.004959424068762264	[46]	[29]	0	hSpCas9	negative selection	11755018
51706601	51706624	12	+	28162770	HEL	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	0.06476276159530764	[205]	[137]	0	hSpCas9	negative selection	11755019
51721675	51721698	12	+	28162770	HEL	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	0.6078050418909698	[208]	[203]	5	hSpCas9	negative selection	11755020
51721698	51721721	12	-	28162770	HEL	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-2.527186169441955	[8]	[0]	-8	hSpCas9	negative selection	11755021
51721662	51721685	12	+	28162770	MV411	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	0.42146695055782407	[116]	[131]	4	hSpCas9	negative selection	11924378
51721818	51721841	12	+	28162770	MV411	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.9709199155853592	[42]	[70]	8	hSpCas9	negative selection	11924379
51769122	51769145	12	-	28162770	MV411	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.22096533942158428	[164]	[161]	2	hSpCas9	negative selection	11924380
51662807	51662830	12	+	28162770	MV411	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.3786820840610279	[188]	[206]	3	hSpCas9	negative selection	11924381
51702856	51702879	12	-	28162770	MV411	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	-0.7198962602969028	[130]	[66]	-5	hSpCas9	negative selection	11924382
51705533	51705556	12	+	28162770	MV411	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	-0.10619940383192494	[45]	[35]	-1	hSpCas9	negative selection	11924383
51706552	51706575	12	+	28162770	MV411	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	-0.17998367295190087	[38]	[28]	-1	hSpCas9	negative selection	11924384
51706601	51706624	12	+	28162770	MV411	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	-0.558240793467445	[214]	[122]	-4	hSpCas9	negative selection	11924385
51721675	51721698	12	+	28162770	MV411	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	0.20211356027328498	[96]	[93]	1	hSpCas9	negative selection	11924386
51721698	51721721	12	-	28162770	MV411	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-0.9224874506595375	[8]	[3]	-6	hSpCas9	negative selection	11924387
51721662	51721685	12	+	28162770	MONOMAC1	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	-0.09847301257596425	[98]	[105]	-1	hSpCas9	negative selection	12093744
51721818	51721841	12	+	28162770	MONOMAC1	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	-0.5111454374876168	[45]	[36]	-4	hSpCas9	negative selection	12093745
51769122	51769145	12	-	28162770	MONOMAC1	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.13608945443267273	[76]	[96]	1	hSpCas9	negative selection	12093746
51662807	51662830	12	+	28162770	MONOMAC1	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	-0.3958870745286577	[232]	[202]	-3	hSpCas9	negative selection	12093747
51702856	51702879	12	-	28162770	MONOMAC1	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	-1.4085409522532655	[87]	[37]	-8	hSpCas9	negative selection	12093748
51705533	51705556	12	+	28162770	MONOMAC1	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	1.5134565357454612	[32]	[107]	9	hSpCas9	negative selection	12093749
51706552	51706575	12	+	28162770	MONOMAC1	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	0.5273287103270192	[22]	[37]	5	hSpCas9	negative selection	12093750
51706601	51706624	12	+	28162770	MONOMAC1	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	-0.3834499712904351	[98]	[86]	-3	hSpCas9	negative selection	12093751
51721675	51721698	12	+	28162770	MONOMAC1	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	0.2662097452619099	[102]	[141]	2	hSpCas9	negative selection	12093752
51721698	51721721	12	-	28162770	MONOMAC1	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-0.027111845617241226	[7]	[8]	0	hSpCas9	negative selection	12093753
51721662	51721685	12	+	28162770	OCIAML2	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	-0.1367290886887229	[23]	[120]	-1	hSpCas9	negative selection	12263110
51721818	51721841	12	+	28162770	OCIAML2	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	1.0529321308148516	[9]	[114]	8	hSpCas9	negative selection	12263111
51769122	51769145	12	-	28162770	OCIAML2	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	1.293656374923557	[16]	[230]	9	hSpCas9	negative selection	12263112
51662807	51662830	12	+	28162770	OCIAML2	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.27479734767224107	[50]	[341]	2	hSpCas9	negative selection	12263113
51702856	51702879	12	-	28162770	OCIAML2	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	0.09327105995116525	[22]	[135]	0	hSpCas9	negative selection	12263114
51705533	51705556	12	+	28162770	OCIAML2	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	0.37736708131278895	[9]	[71]	3	hSpCas9	negative selection	12263115
51706552	51706575	12	+	28162770	OCIAML2	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	0.031870515287022005	[5]	[33]	0	hSpCas9	negative selection	12263116
51706601	51706624	12	+	28162770	OCIAML2	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	0.25568852472453657	[33]	[224]	2	hSpCas9	negative selection	12263117
51721675	51721698	12	+	28162770	OCIAML2	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	-1.019968416232596	[29]	[81]	-6	hSpCas9	negative selection	12263118
51721698	51721721	12	-	28162770	OCIAML2	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-2.4706298252421615	[1]	[1]	-8	hSpCas9	negative selection	12263119
51721662	51721685	12	+	28162770	OCIAML3	viability	GGATGACGAGCACAGCACGGTGG	SCN8A	ENSG00000196876	-0.31938526021515745	[30]	[74]	-2	hSpCas9	negative selection	12432476
51721818	51721841	12	+	28162770	OCIAML3	viability	CGTGAAGCGCAACAGCACGGTGG	SCN8A	ENSG00000196876	0.5635336366623167	[12]	[57]	5	hSpCas9	negative selection	12432477
51769122	51769145	12	-	28162770	OCIAML3	viability	TCTGGAAGTCACCATTCCGGTGG	SCN8A	ENSG00000196876	0.71699089440494	[52]	[262]	6	hSpCas9	negative selection	12432478
51662807	51662830	12	+	28162770	OCIAML3	viability	AGGATGAGAAGATGGCAGCGCGG	SCN8A	ENSG00000196876	0.23115855784990152	[45]	[162]	2	hSpCas9	negative selection	12432479
51702856	51702879	12	-	28162770	OCIAML3	viability	AAGGCGAAATAATGCCAAGAAGG	SCN8A	ENSG00000196876	1.180432659260706	[18]	[129]	8	hSpCas9	negative selection	12432480
51705533	51705556	12	+	28162770	OCIAML3	viability	GAATCAGGCAACACTGGAGGAGG	SCN8A	ENSG00000196876	0.36946648365072265	[9]	[38]	3	hSpCas9	negative selection	12432481
51706552	51706575	12	+	28162770	OCIAML3	viability	GACGTAACAGGAGAAAGAAGAGG	SCN8A	ENSG00000196876	1.4763816875672349	[14]	[125]	9	hSpCas9	negative selection	12432482
51706601	51706624	12	+	28162770	OCIAML3	viability	GGAGAAAGGGGATCCCGAGAAGG	SCN8A	ENSG00000196876	0.0911190223224248	[50]	[163]	0	hSpCas9	negative selection	12432483
51721675	51721698	12	+	28162770	OCIAML3	viability	AGCACGGTGGAGGAGAGCGAGGG	SCN8A	ENSG00000196876	0.8210298589546805	[41]	[223]	7	hSpCas9	negative selection	12432484
51721698	51721721	12	-	28162770	OCIAML3	viability	GGATGAAGAGGGAGTCCCGGCGG	SCN8A	ENSG00000196876	-1.17897014104532	[2]	[3]	-7	hSpCas9	negative selection	12432485