Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:80274
• Symbol:SCUBE1
• Description:signal peptide, CUB domain and EGF like domain containing 1

DataSource: http://genomecrispr.dkfz.de/#!/results/SCUBE1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
43231845	43231868	22	-	26472758	Jiyoye	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	0.8005178096853982	[133]	[175]	5	hSpCas9	negative selection	143353
43229071	43229094	22	-	26472758	Jiyoye	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-2.762749619936439	[8]	[0]	-9	hSpCas9	negative selection	143354
43208151	43208174	22	+	26472758	Jiyoye	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-2.2302545391094184	[55]	[8]	-8	hSpCas9	negative selection	143355
43291150	43291173	22	-	26472758	Jiyoye	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	-0.1830237675814299	[413]	[274]	-1	hSpCas9	negative selection	143356
43291121	43291144	22	-	26472758	Jiyoye	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	1.3659527187793605	[70]	[137]	7	hSpCas9	negative selection	143357
43291037	43291060	22	+	26472758	Jiyoye	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.9921378822270296	[207]	[311]	6	hSpCas9	negative selection	143358
43262774	43262797	22	-	26472758	Jiyoye	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-7.419373105785041	[226]	[0]	-9	hSpCas9	negative selection	143359
43229115	43229138	22	+	26472758	Jiyoye	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	-0.30331800129914166	[125]	[76]	-2	hSpCas9	negative selection	143360
43231845	43231868	22	-	26472758	KBM7	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	-0.3389593515861194	[666,556]	[178,268]	-3	hSpCas9	negative selection	334471
43229071	43229094	22	-	26472758	KBM7	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	0.4042340948382477	[28,38]	[38,5]	4	hSpCas9	negative selection	334472
43208151	43208174	22	+	26472758	KBM7	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-3.167909173330447	[486,376]	[23,20]	-9	hSpCas9	negative selection	334473
43291150	43291173	22	-	26472758	KBM7	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	0.40980665670412963	[1212,1159]	[826,667]	4	hSpCas9	negative selection	334474
43291121	43291144	22	-	26472758	KBM7	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	0.3490824088599047	[678,423]	[463,198]	3	hSpCas9	negative selection	334475
43291037	43291060	22	+	26472758	KBM7	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.17630264880196778	[844,620]	[455,321]	1	hSpCas9	negative selection	334476
43262774	43262797	22	-	26472758	KBM7	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-4.535209931701361	[573,387]	[16,2]	-9	hSpCas9	negative selection	334477
43229115	43229138	22	+	26472758	KBM7	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	0.07714235868037397	[600,335]	[192,256]	0	hSpCas9	negative selection	334478
43231845	43231868	22	-	26472758	Raji	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	0.13676734215469386	[242]	[61]	1	hSpCas9	negative selection	525589
43229071	43229094	22	-	26472758	Raji	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-2.699971386684005	[27]	[0]	-9	hSpCas9	negative selection	525590
43208151	43208174	22	+	26472758	Raji	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-3.102069830255351	[110]	[2]	-9	hSpCas9	negative selection	525591
43291150	43291173	22	-	26472758	Raji	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	0.19144780016207386	[599]	[158]	1	hSpCas9	negative selection	525592
43291121	43291144	22	-	26472758	Raji	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	0.7305292299826436	[173]	[66]	6	hSpCas9	negative selection	525593
43291037	43291060	22	+	26472758	Raji	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.3407622757171828	[381]	[69]	-3	hSpCas9	negative selection	525594
43262774	43262797	22	-	26472758	Raji	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-3.312155356140185	[213]	[4]	-9	hSpCas9	negative selection	525595
43229115	43229138	22	+	26472758	Raji	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	0.7739598016484075	[188]	[74]	7	hSpCas9	negative selection	525596
43231845	43231868	22	-	26472758	K562	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	0.27843883659895	[460]	[471]	2	hSpCas9	negative selection	716707
43229071	43229094	22	-	26472758	K562	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-3.843044113583893	[33]	[1]	-9	hSpCas9	negative selection	716708
43208151	43208174	22	+	26472758	K562	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-6.3666060696409055	[390]	[3]	-9	hSpCas9	negative selection	716709
43291150	43291173	22	-	26472758	K562	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	0.29312814845498236	[960]	[993]	2	hSpCas9	negative selection	716710
43291121	43291144	22	-	26472758	K562	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	0.5311096424972677	[372]	[454]	4	hSpCas9	negative selection	716711
43291037	43291060	22	+	26472758	K562	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.6756409944064957	[553]	[746]	5	hSpCas9	negative selection	716712
43262774	43262797	22	-	26472758	K562	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-7.490290892559392	[425]	[1]	-9	hSpCas9	negative selection	716713
43229115	43229138	22	+	26472758	K562	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	-0.655746004753758	[320]	[171]	-4	hSpCas9	negative selection	716714
43255498	43255521	22	-	26627737	DLD1	viability	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	-0.09660970717909168	[1398]	[387,471,374]	-1	hSpCas9	negative selection	818176
43258233	43258256	22	-	26627737	DLD1	viability	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.6064918353898248	[363]	[95,91,41]	-5	hSpCas9	negative selection	818177
43291034	43291057	22	+	26627737	DLD1	viability	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	0.11676907638978218	[772]	[260,285,242]	1	hSpCas9	negative selection	818178
43319951	43319974	22	-	26627737	DLD1	viability	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.0897263279438556	[788]	[190,367,236]	0	hSpCas9	negative selection	818179
43339159	43339182	22	+	26627737	DLD1	viability	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.5263792781482414	[352]	[207,156,117]	5	hSpCas9	negative selection	818180
43343249	43343272	22	-	26627737	DLD1	viability	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	-0.054432863611828086	[530]	[203,203,84]	0	hSpCas9	negative selection	818181
43255498	43255521	22	-	26627737	GBM cells	viability after 5 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	-0.04845919446310454	[645]	[313,355]	0	hSpCas9	negative selection	900491
43258233	43258256	22	-	26627737	GBM cells	viability after 5 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	0.114181861788752	[173]	[113,87]	1	hSpCas9	negative selection	900492
43291034	43291057	22	+	26627737	GBM cells	viability after 5 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.32471214638987267	[389]	[190,142]	-5	hSpCas9	negative selection	900493
43319951	43319974	22	-	26627737	GBM cells	viability after 5 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.34827144734840554	[404]	[259,292]	5	hSpCas9	negative selection	900494
43339159	43339182	22	+	26627737	GBM cells	viability after 5 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.1632909472108895	[178]	[97,116]	2	hSpCas9	negative selection	900495
43343249	43343272	22	-	26627737	GBM cells	viability after 5 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.034568974243252004	[141]	[74,80]	0	hSpCas9	negative selection	900496
43255498	43255521	22	-	26627737	GBM cells	viability after 13 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	-0.2558536946410719	[645]	[276,306]	-3	hSpCas9	negative selection	982806
43258233	43258256	22	-	26627737	GBM cells	viability after 13 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	0.20198131143540465	[173]	[128,91]	2	hSpCas9	negative selection	982807
43291034	43291057	22	+	26627737	GBM cells	viability after 13 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.35338649864045196	[389]	[190,144]	-4	hSpCas9	negative selection	982808
43319951	43319974	22	-	26627737	GBM cells	viability after 13 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.3204462333767163	[404]	[312,242]	4	hSpCas9	negative selection	982809
43339159	43339182	22	+	26627737	GBM cells	viability after 13 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.5738002062917946	[178]	[159,131]	7	hSpCas9	negative selection	982810
43343249	43343272	22	-	26627737	GBM cells	viability after 13 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.3782263170880682	[141]	[103,96]	5	hSpCas9	negative selection	982811
43255498	43255521	22	-	26627737	GBM cells	viability after 21 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	-0.5988352838723849	[645]	[237,225]	-5	hSpCas9	negative selection	1065121
43258233	43258256	22	-	26627737	GBM cells	viability after 21 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	0.37340422102162074	[173]	[146,99]	4	hSpCas9	negative selection	1065122
43291034	43291057	22	+	26627737	GBM cells	viability after 21 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	0.2797744625713342	[389]	[251,261]	3	hSpCas9	negative selection	1065123
43319951	43319974	22	-	26627737	GBM cells	viability after 21 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.2928940355218693	[404]	[326,216]	3	hSpCas9	negative selection	1065124
43339159	43339182	22	+	26627737	GBM cells	viability after 21 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.4577137016202751	[178]	[143,123]	5	hSpCas9	negative selection	1065125
43343249	43343272	22	-	26627737	GBM cells	viability after 21 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.725091045175575	[141]	[126,127]	7	hSpCas9	negative selection	1065126
43255498	43255521	22	-	26627737	RPE1	viability after 9 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.1901008939873412	[1901]	[777,551]	1	hSpCas9	negative selection	1147436
43258233	43258256	22	-	26627737	RPE1	viability after 9 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-2.971552851756894	[342]	[14,11]	-9	hSpCas9	negative selection	1147437
43291034	43291057	22	+	26627737	RPE1	viability after 9 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.5558253256705628	[1628]	[249,471]	-4	hSpCas9	negative selection	1147438
43319951	43319974	22	-	26627737	RPE1	viability after 9 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	-0.1337042084543475	[1669]	[438,524]	-1	hSpCas9	negative selection	1147439
43339159	43339182	22	+	26627737	RPE1	viability after 9 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	1.261665562580371	[360]	[170,399]	7	hSpCas9	negative selection	1147440
43343249	43343272	22	-	26627737	RPE1	viability after 9 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.6588743237720105	[549]	[294,241]	4	hSpCas9	negative selection	1147441
43255498	43255521	22	-	26627737	RPE1	viability after 12 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.5255315135524274	[1901]	[805,660]	3	hSpCas9	negative selection	1229751
43258233	43258256	22	-	26627737	RPE1	viability after 12 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.5871298955858675	[342]	[72,48]	-4	hSpCas9	negative selection	1229752
43291034	43291057	22	+	26627737	RPE1	viability after 12 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.45844520669353717	[1628]	[182,461]	-3	hSpCas9	negative selection	1229753
43319951	43319974	22	-	26627737	RPE1	viability after 12 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.42738159629489947	[1669]	[513,697]	3	hSpCas9	negative selection	1229754
43339159	43339182	22	+	26627737	RPE1	viability after 12 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	1.2575265175976593	[360]	[176,289]	7	hSpCas9	negative selection	1229755
43343249	43343272	22	-	26627737	RPE1	viability after 12 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.4014216631739282	[549]	[200,188]	2	hSpCas9	negative selection	1229756
43255498	43255521	22	-	26627737	RPE1	viability after 15 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.11153815130461209	[1901]	[677,487]	0	hSpCas9	negative selection	1312066
43258233	43258256	22	-	26627737	RPE1	viability after 15 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-1.339305916043814	[342]	[46,29]	-7	hSpCas9	negative selection	1312067
43291034	43291057	22	+	26627737	RPE1	viability after 15 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-1.3413935656435498	[1628]	[161,200]	-7	hSpCas9	negative selection	1312068
43319951	43319974	22	-	26627737	RPE1	viability after 15 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.7741259739382373	[1669]	[982,638]	5	hSpCas9	negative selection	1312069
43339159	43339182	22	+	26627737	RPE1	viability after 15 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	1.1923615968072487	[360]	[296,171]	6	hSpCas9	negative selection	1312070
43343249	43343272	22	-	26627737	RPE1	viability after 15 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.49564570507148764	[549]	[226,211]	3	hSpCas9	negative selection	1312071
43255498	43255521	22	-	26627737	RPE1	viability after 18 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.30678568132743256	[1901]	[646,621]	2	hSpCas9	negative selection	1394381
43258233	43258256	22	-	26627737	RPE1	viability after 18 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-1.3552722235636967	[342]	[55,14]	-7	hSpCas9	negative selection	1394382
43291034	43291057	22	+	26627737	RPE1	viability after 18 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.34221746183259505	[1628]	[354,337]	-2	hSpCas9	negative selection	1394383
43319951	43319974	22	-	26627737	RPE1	viability after 18 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.34715491052111136	[1669]	[639,501]	2	hSpCas9	negative selection	1394384
43339159	43339182	22	+	26627737	RPE1	viability after 18 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	1.0102662628685335	[360]	[275,110]	6	hSpCas9	negative selection	1394385
43343249	43343272	22	-	26627737	RPE1	viability after 18 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.7964942095886769	[549]	[149,372]	5	hSpCas9	negative selection	1394386
43255498	43255521	22	-	26627737	HeLa	viability after 8 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.3910935080313769	[843]	[517,425,506]	3	hSpCas9	negative selection	1476696
43258233	43258256	22	-	26627737	HeLa	viability after 8 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.46611667864321493	[257]	[151,64,44]	-4	hSpCas9	negative selection	1476697
43291034	43291057	22	+	26627737	HeLa	viability after 8 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.29705256798268875	[623]	[468,107,145]	-3	hSpCas9	negative selection	1476698
43319951	43319974	22	-	26627737	HeLa	viability after 8 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.5144602959618587	[514]	[460,308,227]	4	hSpCas9	negative selection	1476699
43339159	43339182	22	+	26627737	HeLa	viability after 8 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.11558059593916123	[332]	[170,100,198]	1	hSpCas9	negative selection	1476700
43343249	43343272	22	-	26627737	HeLa	viability after 8 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	-0.1078043753149518	[218]	[134,43,95]	-1	hSpCas9	negative selection	1476701
43255498	43255521	22	-	26627737	HeLa	viability after 12 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.13706451902483718	[843]	[308,444,387]	1	hSpCas9	negative selection	1559011
43258233	43258256	22	-	26627737	HeLa	viability after 12 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.5791492672768952	[257]	[23,115,67]	-5	hSpCas9	negative selection	1559012
43291034	43291057	22	+	26627737	HeLa	viability after 12 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.2128611048279046	[623]	[378,156,142]	-2	hSpCas9	negative selection	1559013
43319951	43319974	22	-	26627737	HeLa	viability after 12 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	1.1605067784937564	[514]	[448,536,433]	8	hSpCas9	negative selection	1559014
43339159	43339182	22	+	26627737	HeLa	viability after 12 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.7481201726122982	[332]	[319,117,269]	6	hSpCas9	negative selection	1559015
43343249	43343272	22	-	26627737	HeLa	viability after 12 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.09293728662547396	[218]	[59,91,136]	0	hSpCas9	negative selection	1559016
43255498	43255521	22	-	26627737	HeLa	viability after 15 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.6336678775070386	[843]	[520,477,605]	5	hSpCas9	negative selection	1641326
43258233	43258256	22	-	26627737	HeLa	viability after 15 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.34932768566024275	[257]	[93,72,79]	-3	hSpCas9	negative selection	1641327
43291034	43291057	22	+	26627737	HeLa	viability after 15 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.967027766192488	[623]	[172,89,125]	-7	hSpCas9	negative selection	1641328
43319951	43319974	22	-	26627737	HeLa	viability after 15 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.9639101630692739	[514]	[194,427,622]	7	hSpCas9	negative selection	1641329
43339159	43339182	22	+	26627737	HeLa	viability after 15 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.030998885740698284	[332]	[248,51,110]	0	hSpCas9	negative selection	1641330
43343249	43343272	22	-	26627737	HeLa	viability after 15 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.290294688368415	[218]	[55,171,98]	2	hSpCas9	negative selection	1641331
43255498	43255521	22	-	26627737	HeLa	viability after 18 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.6347650061445114	[843]	[354,389,605]	5	hSpCas9	negative selection	1723641
43258233	43258256	22	-	26627737	HeLa	viability after 18 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.33703445459453085	[257]	[59,65,79]	-3	hSpCas9	negative selection	1723642
43291034	43291057	22	+	26627737	HeLa	viability after 18 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.9778854333128073	[623]	[112,75,125]	-7	hSpCas9	negative selection	1723643
43319951	43319974	22	-	26627737	HeLa	viability after 18 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.9780688662125523	[514]	[130,363,622]	7	hSpCas9	negative selection	1723644
43339159	43339182	22	+	26627737	HeLa	viability after 18 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.010957590710042264	[332]	[164,40,110]	0	hSpCas9	negative selection	1723645
43343249	43343272	22	-	26627737	HeLa	viability after 18 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.22552528310988473	[218]	[30,138,98]	2	hSpCas9	negative selection	1723646
43255498	43255521	22	-	26627737	HCT116	viability after 6 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.5092854384470573	[1686]	[410,358]	3	hSpCas9	negative selection	1805956
43258233	43258256	22	-	26627737	HCT116	viability after 6 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	0.10714936712634382	[319]	[146,2]	0	hSpCas9	negative selection	1805957
43291034	43291057	22	+	26627737	HCT116	viability after 6 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	0.2575858471647645	[1013]	[109,234]	1	hSpCas9	negative selection	1805958
43319951	43319974	22	-	26627737	HCT116	viability after 6 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	1.5177835893173435	[1237]	[1148,230]	7	hSpCas9	negative selection	1805959
43339159	43339182	22	+	26627737	HCT116	viability after 6 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	-0.6769252789402542	[690]	[114,41]	-4	hSpCas9	negative selection	1805960
43343249	43343272	22	-	26627737	HCT116	viability after 6 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	-2.4084545447820376	[366]	[6,12]	-8	hSpCas9	negative selection	1805961
43255498	43255521	22	-	26627737	HCT116	viability after 8 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	-0.10309737758666548	[812]	[470,427,353]	-1	hSpCas9	negative selection	1888271
43258233	43258256	22	-	26627737	HCT116	viability after 8 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.3569196059773709	[227]	[77,122,92]	-4	hSpCas9	negative selection	1888272
43291034	43291057	22	+	26627737	HCT116	viability after 8 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	0.3107667414903553	[417]	[261,254,338]	3	hSpCas9	negative selection	1888273
43319951	43319974	22	-	26627737	HCT116	viability after 8 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.1558467412673955	[488]	[462,265,175]	1	hSpCas9	negative selection	1888274
43339159	43339182	22	+	26627737	HCT116	viability after 8 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.1741052669041346	[239]	[203,127,116]	2	hSpCas9	negative selection	1888275
43343249	43343272	22	-	26627737	HCT116	viability after 8 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.16273725435281655	[195]	[153,64,143]	2	hSpCas9	negative selection	1888276
43255498	43255521	22	-	26627737	HCT116	viability after 9 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.042810579707078134	[1686]	[210,663]	0	hSpCas9	negative selection	1970586
43258233	43258256	22	-	26627737	HCT116	viability after 9 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.7260279606434762	[319]	[73,33]	-5	hSpCas9	negative selection	1970587
43291034	43291057	22	+	26627737	HCT116	viability after 9 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.034440904335301115	[1013]	[236,285]	0	hSpCas9	negative selection	1970588
43319951	43319974	22	-	26627737	HCT116	viability after 9 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.07954309101002255	[1237]	[498,230]	0	hSpCas9	negative selection	1970589
43339159	43339182	22	+	26627737	HCT116	viability after 9 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	-0.02569697699888221	[690]	[340,54]	0	hSpCas9	negative selection	1970590
43343249	43343272	22	-	26627737	HCT116	viability after 9 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.5400348478893577	[366]	[175,115]	4	hSpCas9	negative selection	1970591
43255498	43255521	22	-	26627737	HCT116	viability after 12 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	-0.15553920613259242	[812]	[330,367,455]	-2	hSpCas9	negative selection	2052901
43258233	43258256	22	-	26627737	HCT116	viability after 12 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.3808353812181879	[227]	[82,97,95]	-4	hSpCas9	negative selection	2052902
43291034	43291057	22	+	26627737	HCT116	viability after 12 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	0.48116319631932525	[417]	[424,244,237]	4	hSpCas9	negative selection	2052903
43319951	43319974	22	-	26627737	HCT116	viability after 12 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.47992907424229303	[488]	[255,431,397]	4	hSpCas9	negative selection	2052904
43339159	43339182	22	+	26627737	HCT116	viability after 12 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.11300837747899209	[239]	[161,137,106]	1	hSpCas9	negative selection	2052905
43343249	43343272	22	-	26627737	HCT116	viability after 12 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	-0.12951484268961055	[195]	[98,91,90]	-1	hSpCas9	negative selection	2052906
43255498	43255521	22	-	26627737	HCT116	viability after 15 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.21572866185544592	[812]	[464,507,642]	2	hSpCas9	negative selection	2135216
43258233	43258256	22	-	26627737	HCT116	viability after 15 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.02297039280960922	[227]	[147,116,123]	0	hSpCas9	negative selection	2135217
43291034	43291057	22	+	26627737	HCT116	viability after 15 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	0.3095958121089104	[417]	[298,318,274]	3	hSpCas9	negative selection	2135218
43319951	43319974	22	-	26627737	HCT116	viability after 15 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	-0.2972318312624338	[488]	[166,270,239]	-3	hSpCas9	negative selection	2135219
43339159	43339182	22	+	26627737	HCT116	viability after 15 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.06093571741906978	[239]	[292,54,101]	0	hSpCas9	negative selection	2135220
43343249	43343272	22	-	26627737	HCT116	viability after 15 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.12441661275370086	[195]	[68,205,86]	1	hSpCas9	negative selection	2135221
43255498	43255521	22	-	26627737	HCT116	viability after 18 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.680062062577139	[812]	[752,563,573]	5	hSpCas9	negative selection	2217531
43258233	43258256	22	-	26627737	HCT116	viability after 18 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	0.09541423552104344	[227]	[67,114,172]	0	hSpCas9	negative selection	2217532
43291034	43291057	22	+	26627737	HCT116	viability after 18 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.17705038929421246	[417]	[175,198,158]	-2	hSpCas9	negative selection	2217533
43319951	43319974	22	-	26627737	HCT116	viability after 18 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	-0.16372696284460142	[488]	[280,114,244]	-1	hSpCas9	negative selection	2217534
43339159	43339182	22	+	26627737	HCT116	viability after 18 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	-0.23188842595078152	[239]	[136,77,81]	-2	hSpCas9	negative selection	2217535
43343249	43343272	22	-	26627737	HCT116	viability after 18 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	0.43232096230307576	[195]	[54,179,145]	3	hSpCas9	negative selection	2217536
43343219	43343244	22	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CGCTGGCACTTGTGCGTGCTGCTGG	SCUBE1	ENSG00000159307	0.8610005234914657	[1650,1050,1476]	[0,0,0]	3	hSpCas9	positive selection	2381281
43343203	43343228	22	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGCTGCTGGCCCTGGGCACACGCGG	SCUBE1	ENSG00000159307	1.09238262195628	[1553,996,1019]	[0,0,0]	3	hSpCas9	positive selection	2381282
43343202	43343226	22	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CTGCTGGCCCTGGGCACACGCGGG	SCUBE1	ENSG00000159307	0.502093201670318	[2147,1603,1609]	[0,0,0]	1	hSpCas9	positive selection	2381283
43343219	43343244	22	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CGCTGGCACTTGTGCGTGCTGCTGG	SCUBE1	ENSG00000159307	0.8615202569995141	[1650,1050,1476]	[0,0,0]	2	hSpCas9	positive selection	2382621
43343219	43343244	22	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CGCTGGCACTTGTGCGTGCTGCTGG	SCUBE1	ENSG00000159307	0.8615202569995141	[1650,1050,1476]	[0,0,0]	2	hSpCas9	positive selection	2382622
43343203	43343228	22	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGCTGCTGGCCCTGGGCACACGCGG	SCUBE1	ENSG00000159307	4.414116269971192	[1553,996,1019]	[0,27,0]	7	hSpCas9	positive selection	2382623
43343203	43343228	22	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGCTGCTGGCCCTGGGCACACGCGG	SCUBE1	ENSG00000159307	4.414116269971192	[1553,996,1019]	[0,27,0]	7	hSpCas9	positive selection	2382624
43343202	43343226	22	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTGCTGGCCCTGGGCACACGCGGG	SCUBE1	ENSG00000159307	0.5018776071206151	[2147,1603,1609]	[0,0,0]	1	hSpCas9	positive selection	2382625
43343202	43343226	22	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTGCTGGCCCTGGGCACACGCGGG	SCUBE1	ENSG00000159307	0.5018776071206151	[2147,1603,1609]	[0,0,0]	1	hSpCas9	positive selection	2382626
43266073	43266096	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCACTCTGTCGCCCTGG	SCUBE1	ENSG00000159307	0.8460111869825209	[4,1]	[1,0]	3	dCas9-VP64	positive selection	2391725
43318771	43318794	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACACCATTGCACTCCAGCCCGG	SCUBE1	ENSG00000159307	1.262249387691805	[54,80]	[6,66]	5	dCas9-VP64	positive selection	2396386
43266073	43266096	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCACTCTGTCGCCCTGG	SCUBE1	ENSG00000159307	-0.7793844065766207	[74,18]	[14,2]	-7	dCas9-VP64	positive selection	2486980
43318771	43318794	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACACCATTGCACTCCAGCCCGG	SCUBE1	ENSG00000159307	1.3472067688576927	[201,316]	[301,132]	7	dCas9-VP64	positive selection	2491641
43319998	43320021	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGAGTGCATCAACATCCCGGGG	SCUBE1	ENSG00000159307	-0.304580999330465	[3,2]	[1,1]	-4	hSpCas9	positive selection	3019071
43231800	43231823	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCGCACTCGAAGCTGCCCACGG	SCUBE1	ENSG00000159307	-0.6108369067332597	[2,2]	[1,0]	-7	hSpCas9	positive selection	3019072
43262729	43262752	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGACCTTGCCCAAAACCAGAAGG	SCUBE1	ENSG00000159307	-0.3299100899194277	[3,3]	[4,0]	-5	hSpCas9	positive selection	3019073
43319998	43320021	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGAGTGCATCAACATCCCGGGG	SCUBE1	ENSG00000159307	-0.03458664401203808	[3,3]	[2,1]	0	hSpCas9	positive selection	3086929
43231800	43231823	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCGCACTCGAAGCTGCCCACGG	SCUBE1	ENSG00000159307	0.1309609032739507	[2,2]	[1,2]	2	hSpCas9	positive selection	3086930
43262729	43262752	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGACCTTGCCCAAAACCAGAAGG	SCUBE1	ENSG00000159307	-0.6664113953544362	[3,3]	[2,0]	-8	hSpCas9	positive selection	3086931
43339221	43339244		-	24336571	A375	resistance to PLX after 7 days	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.20168755892095902	[5,4]	[4,4]	-6	hSpCas9	positive selection	3143004
43320000	43320023		+	24336571	A375	resistance to PLX after 7 days	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.03569039748673125	[18,16]	[15,18]	-1	hSpCas9	positive selection	3143006
43339221	43339244		-	24336571	A375	resistance to PLX after 14 days	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.10404589976560863	[4,5]	[1,1]	-1	hSpCas9	positive selection	3200797
43320000	43320023		+	24336571	A375	resistance to PLX after 14 days	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.06470803079013743	[21,18]	[7,9]	0	hSpCas9	positive selection	3200799
43339221	43339244		-	24336571	A375	viability after 7 days	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.2369654080539607	[4]	[5,4]	3	hSpCas9	negative selection	3258590
43320000	43320023		+	24336571	A375	viability after 7 days	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.15551989621116635	[16]	[18,16]	2	hSpCas9	negative selection	3258592
43339221	43339244		-	24336571	A375	viability after 14 days	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.24302746730223146	[4]	[4,5]	3	hSpCas9	negative selection	3316383
43320000	43320023		+	24336571	A375	viability after 14 days	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.3644526545819228	[16]	[21,18]	5	hSpCas9	negative selection	3316385
43291104	43291127	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	0.8143827155971068	[86,86]	[0,0]	4	hSpCas9	positive selection	3391508
43339170	43339193	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.6793117275567355	[244,244]	[0,0]	-5	hSpCas9	positive selection	3391509
43320000	43320023	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	-1.316320976047487	[380,380]	[0,0]	-8	hSpCas9	positive selection	3391510
43319998	43320021	22	-	26780180	HT29	viability (Avana library 4 designs)	ACGAGTGCATCAACATCCCGGGG	SCUBE1	ENSG00000159307	1.18035748789716	[]	[]	4	hSpCas9	negative selection	3457503
43231799	43231822	22	+	26780180	HT29	viability (Avana library 4 designs)	GCCGCACTCGAAGCTGCCCACGG	SCUBE1	ENSG00000159307	2.24140290586857	[]	[]	7	hSpCas9	negative selection	3457504
43262729	43262752	22	-	26780180	HT29	viability (Avana library 4 designs)	TGACCTTGCCCAAAACCAGAAGG	SCUBE1	ENSG00000159307	-0.118288767384587	[]	[]	-2	hSpCas9	negative selection	3457505
43319998	43320021	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACGAGTGCATCAACATCCCGGGG	SCUBE1	ENSG00000159307	1.97951006154181	[]	[]	3	hSpCas9	negative selection	3556487
43262729	43262752	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGACCTTGCCCAAAACCAGAAGG	SCUBE1	ENSG00000159307	-0.522932788439405	[]	[]	0	hSpCas9	negative selection	3556488
43231799	43231822	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCGCACTCGAAGCTGCCCACGG	SCUBE1	ENSG00000159307	3.33872108193229	[]	[]	5	hSpCas9	negative selection	3556489
43339122	43339145	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGCAAGCCAGGCTACAAGGGGG	SCUBE1	ENSG00000159307	1.0121777143085	[]	[]	1	hSpCas9	negative selection	3556490
43229087	43229110	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCCGTAGAGGATGTAGCCGCGG	SCUBE1	ENSG00000159307	5.97469011545027	[]	[]	9	hSpCas9	negative selection	3556491
43319998	43320021	22	-	26780180	A375	viability (Avana lentiGuide)	ACGAGTGCATCAACATCCCGGGG	SCUBE1	ENSG00000159307	6.08742742731128	[]	[]	5	hSpCas9	negative selection	3665146
43262729	43262752	22	-	26780180	A375	viability (Avana lentiGuide)	TGACCTTGCCCAAAACCAGAAGG	SCUBE1	ENSG00000159307	-5.30606019745788	[]	[]	-8	hSpCas9	negative selection	3665147
43231799	43231822	22	+	26780180	A375	viability (Avana lentiGuide)	GCCGCACTCGAAGCTGCCCACGG	SCUBE1	ENSG00000159307	-0.200693074235959	[]	[]	0	hSpCas9	negative selection	3665148
43339122	43339145	22	-	26780180	A375	viability (Avana lentiGuide)	CTGCAAGCCAGGCTACAAGGGGG	SCUBE1	ENSG00000159307	0.911408252243609	[]	[]	1	hSpCas9	negative selection	3665149
43229087	43229110	22	+	26780180	A375	viability (Avana lentiGuide)	TCCCGTAGAGGATGTAGCCGCGG	SCUBE1	ENSG00000159307	-2.6632343603332	[]	[]	-5	hSpCas9	negative selection	3665150
43319998	43320021	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGAGTGCATCAACATCCCGGGG	SCUBE1	ENSG00000159307	-0.02434002031082194	[4]	[4,4]	0	hSpCas9	positive selection	3773753
43262729	43262752	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGACCTTGCCCAAAACCAGAAGG	SCUBE1	ENSG00000159307	-0.4119486366272579	[4]	[3,2]	-6	hSpCas9	positive selection	3773754
43231799	43231822	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCGCACTCGAAGCTGCCCACGG	SCUBE1	ENSG00000159307	0.3084499053997493	[3]	[4,5]	8	hSpCas9	positive selection	3773755
43339122	43339145	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGCAAGCCAGGCTACAAGGGGG	SCUBE1	ENSG00000159307	0.012076692921275611	[5]	[5,4]	0	hSpCas9	positive selection	3773756
43229087	43229110	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCCGTAGAGGATGTAGCCGCGG	SCUBE1	ENSG00000159307	0.2717587210986727	[4]	[5,5]	7	hSpCas9	positive selection	3773757
43319998	43320021	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGAGTGCATCAACATCCCGGGG	SCUBE1	ENSG00000159307	-0.4308774856755476	[4]	[2,2]	-5	hSpCas9	positive selection	3882360
43262729	43262752	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGACCTTGCCCAAAACCAGAAGG	SCUBE1	ENSG00000159307	0.02343622094012246	[5]	[2,5]	0	hSpCas9	positive selection	3882361
43231799	43231822	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCGCACTCGAAGCTGCCCACGG	SCUBE1	ENSG00000159307	0.07991609713997072	[4]	[3,4]	1	hSpCas9	positive selection	3882362
43339122	43339145	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGCAAGCCAGGCTACAAGGGGG	SCUBE1	ENSG00000159307	0.23521901814778373	[6]	[6,6]	6	hSpCas9	positive selection	3882363
43229087	43229110	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCCGTAGAGGATGTAGCCGCGG	SCUBE1	ENSG00000159307	0.0848783099619019	[5]	[5,3]	1	hSpCas9	positive selection	3882364
43339221	43339244	22	-	26780180	A375	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.517205126460073	[]	[]	1	hSpCas9	negative selection	3992397
43320000	43320023	22	-	26780180	A375	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.71107478594953	[]	[]	2	hSpCas9	negative selection	3992398
43320000	43320023	22	+	26780180	A375	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	1.12965751616096	[]	[]	5	hSpCas9	negative selection	3992399
43291104	43291127	22	+	26780180	A375	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	1.26227318785272	[]	[]	6	hSpCas9	negative selection	3992400
43339170	43339193	22	+	26780180	A375	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	0.857335937018534	[]	[]	3	hSpCas9	negative selection	3992401
43291037	43291060	22	+	26780180	A375	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.872444669187646	[]	[]	3	hSpCas9	negative selection	3992402
43339221	43339244	22	-	26780180	HT29	viability (GeCKOv2 library)	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.586451139775216	[]	[]	2	hSpCas9	negative selection	4100363
43320000	43320023	22	-	26780180	HT29	viability (GeCKOv2 library)	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.770230085820721	[]	[]	3	hSpCas9	negative selection	4100364
43320000	43320023	22	+	26780180	HT29	viability (GeCKOv2 library)	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	1.03117185156572	[]	[]	5	hSpCas9	negative selection	4100365
43291104	43291127	22	+	26780180	HT29	viability (GeCKOv2 library)	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	1.5911672185904	[]	[]	8	hSpCas9	negative selection	4100366
43339170	43339193	22	+	26780180	HT29	viability (GeCKOv2 library)	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	0.746354273426342	[]	[]	3	hSpCas9	negative selection	4100367
43291037	43291060	22	+	26780180	HT29	viability (GeCKOv2 library)	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.00257453588817018	[]	[]	0	hSpCas9	negative selection	4100368
43339221	43339244	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.1676001530339335	[2]	[1,0]	-4	hSpCas9	positive selection	4168794
43320000	43320023	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.018235205376511923	[3]	[1,3]	0	hSpCas9	positive selection	4168796
43339221	43339244	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.715710930123985	[2]	[2,2,5,0]	4	hSpCas9	positive selection	4232816
43320000	43320023	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.016946070764764197	[3]	[3,0,2,0]	0	hSpCas9	positive selection	4232818
43339221	43339244	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.1757992344448085	[0]	[0,0]	-4	hSpCas9	positive selection	4296700
43291037	43291060	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.3574562974721017	[3]	[3,3]	7	hSpCas9	positive selection	4296701
43320000	43320023	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.36224962631168245	[2]	[2,2]	7	hSpCas9	positive selection	4296702
43291104	43291127	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	0.06293903136626894	[2]	[2,1]	1	hSpCas9	positive selection	4360954
43339170	43339193	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.04124354209209846	[4]	[4,2]	-1	hSpCas9	positive selection	4360955
43320000	43320023	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.13999031218050945	[3]	[3,2]	3	hSpCas9	positive selection	4360956
43231752	43231774	22	-	27760321	OCIAML3	viability	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.33896649773762555	[830,680]	[771,707]	4	hSpCas9	negative selection	4437350
43231788	43231810	22	-	27760321	OCIAML3	viability	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	0.007384001579122668	[551,467]	[313,510]	0	hSpCas9	negative selection	4437351
43258255	43258277	22	+	27760321	OCIAML3	viability	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	0.5742027672386134	[644,604]	[574,927]	6	hSpCas9	negative selection	4437352
43231752	43231774	22	-	27760321	OCIAML2	viability	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.40739874605932125	[830,680]	[675,979]	5	hSpCas9	negative selection	4520813
43231788	43231810	22	-	27760321	OCIAML2	viability	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	0.14171458553952418	[551,467]	[390,535]	1	hSpCas9	negative selection	4520814
43258255	43258277	22	+	27760321	OCIAML2	viability	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	0.03864093050976858	[644,604]	[463,592]	0	hSpCas9	negative selection	4520815
43231752	43231774	22	-	27760321	MV411	viability	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.8786572965550984	[830,680]	[700,1230]	6	hSpCas9	negative selection	4604276
43231788	43231810	22	-	27760321	MV411	viability	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	0.34149330092854013	[551,467]	[362,517]	2	hSpCas9	negative selection	4604277
43258255	43258277	22	+	27760321	MV411	viability	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	-0.347308901996764	[644,604]	[335,306]	-2	hSpCas9	negative selection	4604278
43231752	43231774	22	-	27760321	HL60	viability	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.004898522229984659	[830,680]	[604,628]	0	hSpCas9	negative selection	4687739
43231788	43231810	22	-	27760321	HL60	viability	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	0.2417012752152101	[551,467]	[519,459]	3	hSpCas9	negative selection	4687740
43258255	43258277	22	+	27760321	HL60	viability	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	0.22705897389450846	[644,604]	[546,651]	2	hSpCas9	negative selection	4687741
43231752	43231774	22	-	27760321	HT1080	viability	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.8295141269987724	[680,531]	[542,304]	4	hSpCas9	negative selection	4771202
43231788	43231810	22	-	27760321	HT1080	viability	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	-0.09195502922909966	[467,364]	[95,220]	0	hSpCas9	negative selection	4771203
43258255	43258277	22	+	27760321	HT1080	viability	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	-0.544150978615216	[604,471]	[138,155]	-2	hSpCas9	negative selection	4771204
43231752	43231774	22	-	27760321	HT29	viability after 7 days	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.6252956569932832	[680,531]	[1192,1127,1281]	8	hSpCas9	negative selection	4854665
43231788	43231810	22	-	27760321	HT29	viability after 7 days	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	-0.1044605726039894	[467,364]	[497,608,389]	-1	hSpCas9	negative selection	4854666
43258255	43258277	22	+	27760321	HT29	viability after 7 days	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	0.0032875268362138055	[604,471]	[593,698,770]	0	hSpCas9	negative selection	4854667
43231752	43231774	22	-	27760321	HT29	viability after 25 days	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.5856780484569947	[680,531]	[1057,1011,1048]	6	hSpCas9	negative selection	4938128
43231788	43231810	22	-	27760321	HT29	viability after 25 days	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	0.10424322635455838	[467,364]	[445,599,489]	1	hSpCas9	negative selection	4938129
43258255	43258277	22	+	27760321	HT29	viability after 25 days	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	-0.2318416036679674	[604,471]	[467,503,611]	-2	hSpCas9	negative selection	4938130
43231752	43231774	22	-	27760321	HT29	viability after 22 days	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.6240274682302726	[680,531]	[1158,1185,892]	7	hSpCas9	negative selection	5021591
43231788	43231810	22	-	27760321	HT29	viability after 22 days	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	0.23979383328167383	[467,364]	[553,580,570]	2	hSpCas9	negative selection	5021592
43258255	43258277	22	+	27760321	HT29	viability after 22 days	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	-0.1105122417504033	[604,471]	[510,600,619]	-1	hSpCas9	negative selection	5021593
43231752	43231774	22	-	27760321	HT29	viability after 19 days	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.24323704259649914	[680,531]	[977,918,590]	2	hSpCas9	negative selection	5105054
43231788	43231810	22	-	27760321	HT29	viability after 19 days	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	0.196914204699389	[467,364]	[622,566,458]	1	hSpCas9	negative selection	5105055
43258255	43258277	22	+	27760321	HT29	viability after 19 days	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	0.07618215526525174	[604,471]	[526,690,713]	0	hSpCas9	negative selection	5105056
43231752	43231774	22	-	27760321	HT29	viability after 16 days	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.32403702581199034	[680,531]	[794,855,891]	3	hSpCas9	negative selection	5188517
43231788	43231810	22	-	27760321	HT29	viability after 16 days	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	0.18029551503206057	[467,364]	[774,497,334]	2	hSpCas9	negative selection	5188518
43258255	43258277	22	+	27760321	HT29	viability after 16 days	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	-0.3975069294230086	[604,471]	[489,461,422]	-4	hSpCas9	negative selection	5188519
43231752	43231774	22	-	27760321	HT29	viability after 13 days	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.5973274307838458	[680,531]	[1230,1151,824]	7	hSpCas9	negative selection	5271980
43231788	43231810	22	-	27760321	HT29	viability after 13 days	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	0.4220755903958826	[467,364]	[795,691,464]	5	hSpCas9	negative selection	5271981
43258255	43258277	22	+	27760321	HT29	viability after 13 days	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	-0.2108066394721128	[604,471]	[521,586,511]	-2	hSpCas9	negative selection	5271982
43231752	43231774	22	-	27760321	HT29	viability after 10 days	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	0.5951124385860372	[680,531]	[1121,1159,1149]	7	hSpCas9	negative selection	5355443
43231788	43231810	22	-	27760321	HT29	viability after 10 days	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	0.04152827822197444	[467,364]	[676,321,598]	0	hSpCas9	negative selection	5355444
43258255	43258277	22	+	27760321	HT29	viability after 10 days	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	-0.013012269147108402	[604,471]	[612,834,557]	0	hSpCas9	negative selection	5355445
43231752	43231774	22	-	27760321	MOLM13	viability	CCGACGAGCGCACCTGCCAGGG	SCUBE1	ENSG00000159307	1.4180042159979744	[830,680]	[599,1588]	8	hSpCas9	negative selection	5438906
43231788	43231810	22	-	27760321	MOLM13	viability	TCGAGTGCGGCTGCCGGAAGGG	SCUBE1	ENSG00000159307	1.206926712607908	[551,467]	[514,786]	8	hSpCas9	negative selection	5438907
43258255	43258277	22	+	27760321	MOLM13	viability	TCTGGTGGCAACCACACGTGGG	SCUBE1	ENSG00000159307	-0.461341458687641	[644,604]	[117,373]	-3	hSpCas9	negative selection	5438908
43343299	43343322	22	+	27661255	K562	viability	GGCGCGGGGACCCGACCGACCGG	SCUBE1	ENSG00000159307	0.006322557836081377	[618,579]	[480,481]	0	dCas9-KRAB	negative selection	5509717
43342894	43342917	22	-	27661255	K562	viability	GGAGCGAGGAAGAAAGGCGGCGG	SCUBE1	ENSG00000159307	-0.004131802234885684	[1000,1129]	[909,792]	0	dCas9-KRAB	negative selection	5509718
43342956	43342979	22	-	27661255	K562	viability	GTCCGGCGGGGCCGCACCAGGGG	SCUBE1	ENSG00000159307	0.38629893948147465	[191,261]	[266,208]	9	dCas9-KRAB	negative selection	5509719
43343103	43343126	22	-	27661255	K562	viability	GGCCGAGGCGCGGTCCCGGAGGG	SCUBE1	ENSG00000159307	0.42485557683264413	[393,455]	[453,454]	9	dCas9-KRAB	negative selection	5509720
43343309	43343332	22	-	27661255	K562	viability	GCGGGAGCGGCCGGTCGGTCGGG	SCUBE1	ENSG00000159307	-0.5384637368514781	[459,305]	[263,167]	-7	dCas9-KRAB	negative selection	5509721
43343351	43343374	22	-	27661255	K562	viability	GAGCCCGAGCGGTGGCGGAGCGG	SCUBE1	ENSG00000159307	-0.09490202065139391	[771,645]	[565,502]	-4	dCas9-KRAB	negative selection	5509722
43339221	43339244	22	-	27260156	BXPC3	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.2561888581261216	[38]	[36,34,36,25]	-5	hSpCas9	negative selection	5569160
43291037	43291060	22	+	27260156	BXPC3	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.100314387431298	[569]	[607,522,687,757]	2	hSpCas9	negative selection	5569161
43320000	43320023	22	+	27260156	BXPC3	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.47921885689375054	[308]	[246,170,238,275]	-8	hSpCas9	negative selection	5569162
43291104	43291127	22	+	27260156	BXPC3	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.5201069602833425	[265]	[147,206,273,144]	-8	hSpCas9	negative selection	5633414
43339170	43339193	22	+	27260156	BXPC3	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.3540937034310626	[1067]	[701,782,1024,1023]	-7	hSpCas9	negative selection	5633415
43320000	43320023	22	-	27260156	BXPC3	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.10951969423972452	[803]	[848,738,1039,1026]	2	hSpCas9	negative selection	5633416
43339221	43339244	22	-	27260156	A673	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.3158890023636518	[38]	[48,23,41,36]	-7	hSpCas9	negative selection	5690411
43291037	43291060	22	+	27260156	A673	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.08169265905007089	[569]	[947,607,692,672]	2	hSpCas9	negative selection	5690412
43320000	43320023	22	+	27260156	A673	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.14048595457435953	[308]	[428,232,343,353]	-3	hSpCas9	negative selection	5690413
43291104	43291127	22	+	27260156	A673	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.29802749508439297	[265]	[254,296,245,237]	-6	hSpCas9	negative selection	5754665
43339170	43339193	22	+	27260156	A673	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.24188316237700114	[1067]	[1294,979,993,1094]	-5	hSpCas9	negative selection	5754666
43320000	43320023	22	-	27260156	A673	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.1999532596647925	[803]	[1013,1040,993,1391]	5	hSpCas9	negative selection	5754667
43339221	43339244	22	-	27260156	A375	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.11210622468742182	[38]	[111,49,10,26]	1	hSpCas9	negative selection	5811662
43291037	43291060	22	+	27260156	A375	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.03184651686593665	[569]	[705,661,702,545]	0	hSpCas9	negative selection	5811663
43320000	43320023	22	+	27260156	A375	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.12574689637603376	[308]	[400,435,270,239]	-2	hSpCas9	negative selection	5811664
43291104	43291127	22	+	27260156	A375	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.28541335688962965	[265]	[324,188,323,180]	-4	hSpCas9	negative selection	5875916
43339170	43339193	22	+	27260156	A375	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.43307407297692335	[1067]	[909,1213,791,827]	-6	hSpCas9	negative selection	5875917
43320000	43320023	22	-	27260156	A375	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.4453474203348943	[803]	[1660,1134,1077,1224]	6	hSpCas9	negative selection	5875918
43339221	43339244	22	-	27260156	COLO741	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.670719037473102	[38]	[20,12,56]	-8	hSpCas9	negative selection	5932913
43291037	43291060	22	+	27260156	COLO741	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.261776421814573	[569]	[773,872,955]	5	hSpCas9	negative selection	5932914
43320000	43320023	22	+	27260156	COLO741	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.4466006805939142	[308]	[318,249,300]	-7	hSpCas9	negative selection	5932915
43291104	43291127	22	+	27260156	COLO741	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.9830707934554851	[265]	[202,142,171]	-9	hSpCas9	negative selection	5997167
43339170	43339193	22	+	27260156	COLO741	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.7225260402140379	[1067]	[810,786,875]	-9	hSpCas9	negative selection	5997168
43320000	43320023	22	-	27260156	COLO741	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	-0.02365081070856012	[803]	[1113,996,932]	0	hSpCas9	negative selection	5997169
43339221	43339244	22	-	27260156	CAL120	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.6687740476862611	[38]	[45,22,24]	-7	hSpCas9	negative selection	6054164
43291037	43291060	22	+	27260156	CAL120	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.464853211424361	[569]	[768,412,399]	-6	hSpCas9	negative selection	6054165
43320000	43320023	22	+	27260156	CAL120	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.33068892515059184	[308]	[408,641,389]	5	hSpCas9	negative selection	6054166
43291104	43291127	22	+	27260156	CAL120	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	0.009049673414512793	[265]	[308,380,305]	0	hSpCas9	negative selection	6118418
43339170	43339193	22	+	27260156	CAL120	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.6621591119107614	[1067]	[816,649,1044]	-7	hSpCas9	negative selection	6118419
43320000	43320023	22	-	27260156	CAL120	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.11660175122803007	[803]	[1312,1112,865]	1	hSpCas9	negative selection	6118420
43339221	43339244	22	-	27260156	CADOES1	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.3597214557470432	[38]	[33,7,42,27]	-6	hSpCas9	negative selection	6175415
43291037	43291060	22	+	27260156	CADOES1	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.25430900844012416	[569]	[405,380,565,423]	-4	hSpCas9	negative selection	6175416
43320000	43320023	22	+	27260156	CADOES1	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.011624839066952664	[308]	[189,275,249,429]	0	hSpCas9	negative selection	6175417
43291104	43291127	22	+	27260156	CADOES1	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.342807984382946	[265]	[219,185,209,162]	-5	hSpCas9	negative selection	6239669
43339170	43339193	22	+	27260156	CADOES1	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.564082771681773	[1067]	[586,760,586,755]	-7	hSpCas9	negative selection	6239670
43320000	43320023	22	-	27260156	CADOES1	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.23308806116193648	[803]	[820,925,858,910]	4	hSpCas9	negative selection	6239671
43339221	43339244	22	-	27260156	EWS502	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.4592067861210172	[38]	[42,12,36,25]	-7	hSpCas9	negative selection	6296666
43291037	43291060	22	+	27260156	EWS502	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.07567258784153269	[569]	[586,457,429,833]	-1	hSpCas9	negative selection	6296667
43320000	43320023	22	+	27260156	EWS502	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.13492030948933764	[308]	[198,311,312,384]	-2	hSpCas9	negative selection	6296668
43291104	43291127	22	+	27260156	EWS502	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.23327874416689076	[265]	[163,222,214,374]	-4	hSpCas9	negative selection	6360920
43339170	43339193	22	+	27260156	EWS502	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.32902514767411495	[1067]	[802,722,869,1245]	-5	hSpCas9	negative selection	6360921
43320000	43320023	22	-	27260156	EWS502	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.14357266775946176	[803]	[577,855,1060,1341]	2	hSpCas9	negative selection	6360922
43339221	43339244	22	-	27260156	EW8	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.6068840645425748	[38]	[24,34,17,5]	-8	hSpCas9	negative selection	6417917
43291037	43291060	22	+	27260156	EW8	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.1614783880233059	[569]	[390,404,486,352]	-3	hSpCas9	negative selection	6417918
43320000	43320023	22	+	27260156	EW8	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.1244392754836231	[308]	[218,233,175,296]	-2	hSpCas9	negative selection	6417919
43291104	43291127	22	+	27260156	EW8	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.36093957219610007	[265]	[200,126,145,203]	-6	hSpCas9	negative selection	6482171
43339170	43339193	22	+	27260156	EW8	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.3748458944240525	[1067]	[647,901,490,655]	-6	hSpCas9	negative selection	6482172
43320000	43320023	22	-	27260156	EW8	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.3666516898223028	[803]	[776,876,672,1051]	6	hSpCas9	negative selection	6482173
43339221	43339244	22	-	27260156	CORL105	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.5324663716540741	[38]	[121,31,35,71]	8	hSpCas9	negative selection	6539168
43291037	43291060	22	+	27260156	CORL105	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.11459031509683942	[569]	[699,611,994,626]	2	hSpCas9	negative selection	6539169
43320000	43320023	22	+	27260156	CORL105	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.33675854052156107	[308]	[536,387,566,356]	6	hSpCas9	negative selection	6539170
43291104	43291127	22	+	27260156	CORL105	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	0.22980609178503442	[265]	[279,355,524,321]	4	hSpCas9	negative selection	6603422
43339170	43339193	22	+	27260156	CORL105	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.4419732680083779	[1067]	[958,675,1023,1043]	-7	hSpCas9	negative selection	6603423
43320000	43320023	22	-	27260156	CORL105	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.3371862512415892	[803]	[971,1030,1389,1388]	6	hSpCas9	negative selection	6603424
43339221	43339244	22	-	27260156	HS294T	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.38319046295945025	[38]	[34,4,15,21]	5	hSpCas9	negative selection	6660419
43291037	43291060	22	+	27260156	HS294T	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.4320389183039665	[569]	[333,235,343,267]	6	hSpCas9	negative selection	6660420
43320000	43320023	22	+	27260156	HS294T	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.28476137922474487	[308]	[101,75,87,131]	-4	hSpCas9	negative selection	6660421
43291104	43291127	22	+	27260156	HS294T	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.7278081667613571	[265]	[49,62,80,53]	-8	hSpCas9	negative selection	6724673
43339170	43339193	22	+	27260156	HS294T	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	0.14492091149921182	[1067]	[252,365,390,913]	2	hSpCas9	negative selection	6724674
43320000	43320023	22	-	27260156	HS294T	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.6105325372328022	[803]	[635,327,393,538]	7	hSpCas9	negative selection	6724675
43339221	43339244	22	-	27260156	HCC44	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.41243363903501695	[38]	[35,19,42,36]	-6	hSpCas9	negative selection	6781670
43291037	43291060	22	+	27260156	HCC44	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.26186241287640155	[569]	[596,387,831,410]	-4	hSpCas9	negative selection	6781671
43320000	43320023	22	+	27260156	HCC44	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.09580841172188836	[308]	[296,164,587,320]	-1	hSpCas9	negative selection	6781672
43291104	43291127	22	+	27260156	HCC44	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	0.014087040771115222	[265]	[211,270,563,209]	0	hSpCas9	negative selection	6845924
43339170	43339193	22	+	27260156	HCC44	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.46617121891964997	[1067]	[888,813,850,939]	-6	hSpCas9	negative selection	6845925
43320000	43320023	22	-	27260156	HCC44	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.4731987334788189	[803]	[1979,899,1361,941]	7	hSpCas9	negative selection	6845926
43339221	43339244	22	-	27260156	G402	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-1.6781233374566584	[38]	[0,12,42,0]	-9	hSpCas9	negative selection	6902921
43291037	43291060	22	+	27260156	G402	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.7370616055420631	[569]	[370,599,506,203]	-7	hSpCas9	negative selection	6902922
43320000	43320023	22	+	27260156	G402	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.01575337376035446	[308]	[381,267,450,383]	0	hSpCas9	negative selection	6902923
43291104	43291127	22	+	27260156	G402	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	0.320121178376632	[265]	[613,378,357,301]	4	hSpCas9	negative selection	6967175
43339170	43339193	22	+	27260156	G402	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.5767310980502184	[1067]	[1319,913,865,477]	-6	hSpCas9	negative selection	6967176
43320000	43320023	22	-	27260156	G402	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.6407359252412078	[803]	[1877,1854,1415,1055]	7	hSpCas9	negative selection	6967177
43339221	43339244	22	-	27260156	L33	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.07265132469178903	[38]	[30,10,23,67]	1	hSpCas9	negative selection	7024172
43291037	43291060	22	+	27260156	L33	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.1085636006803895	[569]	[644,209,320,786]	2	hSpCas9	negative selection	7024173
43320000	43320023	22	+	27260156	L33	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.07236777393892824	[308]	[317,106,211,258]	-2	hSpCas9	negative selection	7024174
43291104	43291127	22	+	27260156	L33	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.6448897608849621	[265]	[158,49,90,253]	-9	hSpCas9	negative selection	7088426
43339170	43339193	22	+	27260156	L33	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.27945979542903676	[1067]	[845,424,567,734]	-6	hSpCas9	negative selection	7088427
43320000	43320023	22	-	27260156	L33	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.019396805400553552	[803]	[853,336,465,839]	0	hSpCas9	negative selection	7088428
43339221	43339244	22	-	27260156	K562	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.6793700330898038	[38]	[35,144,10,34]	8	hSpCas9	negative selection	7145423
43291037	43291060	22	+	27260156	K562	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.4249414857448331	[569]	[1236,479,449,591]	5	hSpCas9	negative selection	7145424
43320000	43320023	22	+	27260156	K562	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.5722181787698783	[308]	[268,139,227,112]	-6	hSpCas9	negative selection	7145425
43291104	43291127	22	+	27260156	K562	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.5185710964340763	[265]	[254,104,74,220]	-6	hSpCas9	negative selection	7209677
43339170	43339193	22	+	27260156	K562	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.7334737642002729	[1067]	[477,656,571,567]	-7	hSpCas9	negative selection	7209678
43320000	43320023	22	-	27260156	K562	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.311820520948786	[803]	[902,1193,805,677]	4	hSpCas9	negative selection	7209679
43339221	43339244	22	-	27260156	HT29	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.7965286018974158	[38]	[13,22,37,31]	-8	hSpCas9	negative selection	7266674
43291037	43291060	22	+	27260156	HT29	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.03337509377028586	[569]	[750,746,656,572]	0	hSpCas9	negative selection	7266675
43320000	43320023	22	+	27260156	HT29	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.11905683259994598	[308]	[406,502,400,334]	2	hSpCas9	negative selection	7266676
43291104	43291127	22	+	27260156	HT29	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	0.33239935592791087	[265]	[425,627,247,350]	6	hSpCas9	negative selection	7330928
43339170	43339193	22	+	27260156	HT29	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.2819173243047379	[1067]	[1339,1105,991,873]	-5	hSpCas9	negative selection	7330929
43320000	43320023	22	-	27260156	HT29	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.12367741377291219	[803]	[1032,1240,1057,946]	2	hSpCas9	negative selection	7330930
43339221	43339244	22	-	27260156	MHHES1	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.5664632286866329	[38]	[72,66,60,59]	8	hSpCas9	negative selection	7387925
43291037	43291060	22	+	27260156	MHHES1	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.1285121462259567	[569]	[775,935,551,585]	2	hSpCas9	negative selection	7387926
43320000	43320023	22	+	27260156	MHHES1	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.3094849820308805	[308]	[183,334,281,303]	-5	hSpCas9	negative selection	7387927
43291104	43291127	22	+	27260156	MHHES1	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.3099046924467862	[265]	[166,228,357,205]	-5	hSpCas9	negative selection	7452179
43339170	43339193	22	+	27260156	MHHES1	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.6004667992849637	[1067]	[842,975,596,767]	-8	hSpCas9	negative selection	7452180
43320000	43320023	22	-	27260156	MHHES1	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.2447587482572292	[803]	[1131,1201,814,1123]	4	hSpCas9	negative selection	7452181
43339221	43339244	22	-	27260156	MEWO	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.18418944193598064	[38]	[70,4,27]	-4	hSpCas9	negative selection	7509176
43291037	43291060	22	+	27260156	MEWO	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.17398976778681804	[569]	[502,435,484]	-4	hSpCas9	negative selection	7509177
43320000	43320023	22	+	27260156	MEWO	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.008850446380377242	[308]	[390,277,222]	0	hSpCas9	negative selection	7509178
43291104	43291127	22	+	27260156	MEWO	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.33464256692717986	[265]	[243,200,155]	-6	hSpCas9	negative selection	7573430
43339170	43339193	22	+	27260156	MEWO	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.05048872280332706	[1067]	[1393,838,744]	-1	hSpCas9	negative selection	7573431
43320000	43320023	22	-	27260156	MEWO	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.09928656902486344	[803]	[931,726,782]	2	hSpCas9	negative selection	7573432
43339221	43339244	22	-	27260156	LNCAPCLONEFGC	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.0731339846802328	[38]	[31,52,45,17]	1	hSpCas9	negative selection	7630427
43291037	43291060	22	+	27260156	LNCAPCLONEFGC	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.11518749464166095	[569]	[388,629,502,379]	-2	hSpCas9	negative selection	7630428
43320000	43320023	22	+	27260156	LNCAPCLONEFGC	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.23292928110436267	[308]	[336,353,289,326]	3	hSpCas9	negative selection	7630429
43291104	43291127	22	+	27260156	LNCAPCLONEFGC	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.043485014844266145	[265]	[381,70,213,272]	0	hSpCas9	negative selection	7694681
43339170	43339193	22	+	27260156	LNCAPCLONEFGC	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.7310229482497392	[1067]	[506,460,571,798]	-8	hSpCas9	negative selection	7694682
43320000	43320023	22	-	27260156	LNCAPCLONEFGC	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.340487103256491	[803]	[674,1096,1182,764]	5	hSpCas9	negative selection	7694683
43339221	43339244	22	-	27260156	PANC0327	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-1.0622069909893828	[38]	[7,5,12,39]	-8	hSpCas9	negative selection	7751678
43291037	43291060	22	+	27260156	PANC0327	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.38508674587742586	[569]	[337,386,497,323]	-5	hSpCas9	negative selection	7751679
43320000	43320023	22	+	27260156	PANC0327	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.30785103501992506	[308]	[183,556,229,346]	4	hSpCas9	negative selection	7751680
43291104	43291127	22	+	27260156	PANC0327	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.18364241722221253	[265]	[184,237,46,355]	-3	hSpCas9	negative selection	7815932
43339170	43339193	22	+	27260156	PANC0327	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.7793917577789609	[1067]	[549,431,539,703]	-8	hSpCas9	negative selection	7815933
43320000	43320023	22	-	27260156	PANC0327	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.7580797168941361	[803]	[854,1225,917,1799]	9	hSpCas9	negative selection	7815934
43339221	43339244	22	-	27260156	NCIH2009	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.32111250680254777	[38]	[69,42,22]	-4	hSpCas9	negative selection	7872929
43291037	43291060	22	+	27260156	NCIH2009	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.2623637127772194	[569]	[1228,796,894]	3	hSpCas9	negative selection	7872930
43320000	43320023	22	+	27260156	NCIH2009	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.071020983384396	[308]	[527,431,294]	-1	hSpCas9	negative selection	7872931
43291104	43291127	22	+	27260156	NCIH2009	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.45012139985528543	[265]	[303,214,303]	-5	hSpCas9	negative selection	7937183
43339170	43339193	22	+	27260156	NCIH2009	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.4673142747258684	[1067]	[1395,839,1066]	-6	hSpCas9	negative selection	7937184
43320000	43320023	22	-	27260156	NCIH2009	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.541129922697099	[803]	[2021,1438,1519]	7	hSpCas9	negative selection	7937185
43339221	43339244	22	-	27260156	NCIH1373	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.4871846654210503	[38]	[23,24,120,18]	5	hSpCas9	negative selection	7994180
43291037	43291060	22	+	27260156	NCIH1373	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.356999416828141	[569]	[1845,401,584,166]	3	hSpCas9	negative selection	7994181
43320000	43320023	22	+	27260156	NCIH1373	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.6514159569251892	[308]	[327,113,231,61]	-6	hSpCas9	negative selection	7994182
43291104	43291127	22	+	27260156	NCIH1373	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.2585018413971619	[265]	[108,402,313,31]	-3	hSpCas9	negative selection	8058434
43339170	43339193	22	+	27260156	NCIH1373	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-1.3100866635960586	[1067]	[342,418,765,97]	-8	hSpCas9	negative selection	8058435
43320000	43320023	22	-	27260156	NCIH1373	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.7568076840814238	[803]	[1475,1476,1536,418]	7	hSpCas9	negative selection	8058436
43339221	43339244	22	-	27260156	PATU8902	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.8125598554475939	[38]	[21,24,90,264]	8	hSpCas9	negative selection	8115431
43291037	43291060	22	+	27260156	PATU8902	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.395760581564476	[569]	[395,587,965,334]	-4	hSpCas9	negative selection	8115432
43320000	43320023	22	+	27260156	PATU8902	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.006433267016175193	[308]	[299,634,383,401]	0	hSpCas9	negative selection	8115433
43291104	43291127	22	+	27260156	PATU8902	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	0.34922196584109233	[265]	[1043,271,298,282]	3	hSpCas9	negative selection	8179685
43339170	43339193	22	+	27260156	PATU8902	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.36363640307063927	[1067]	[1507,1101,959,1081]	-4	hSpCas9	negative selection	8179686
43320000	43320023	22	-	27260156	PATU8902	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.8429329296853599	[803]	[1654,1725,1922,2838]	8	hSpCas9	negative selection	8179687
43339221	43339244	22	-	27260156	PANC1	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.368234474449435	[38]	[35,40,15,14]	-5	hSpCas9	negative selection	8236682
43291037	43291060	22	+	27260156	PANC1	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.12780122864778298	[569]	[490,437,553,320]	-2	hSpCas9	negative selection	8236683
43320000	43320023	22	+	27260156	PANC1	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.10170043188129851	[308]	[407,410,212,147]	1	hSpCas9	negative selection	8236684
43291104	43291127	22	+	27260156	PANC1	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.16791522069927045	[265]	[125,179,352,156]	-3	hSpCas9	negative selection	8300936
43339170	43339193	22	+	27260156	PANC1	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.11742462753391747	[1067]	[844,1107,758,728]	-2	hSpCas9	negative selection	8300937
43320000	43320023	22	-	27260156	PANC1	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.33685600879974065	[803]	[1007,1034,863,636]	5	hSpCas9	negative selection	8300938
43339221	43339244	22	-	27260156	PANC0813	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.3033343395363537	[38]	[24,35,59,26]	-5	hSpCas9	negative selection	8357933
43291037	43291060	22	+	27260156	PANC0813	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.19128778636851185	[569]	[603,435,668,634]	-3	hSpCas9	negative selection	8357934
43320000	43320023	22	+	27260156	PANC0813	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.18370444491093796	[308]	[375,495,468,309]	3	hSpCas9	negative selection	8357935
43291104	43291127	22	+	27260156	PANC0813	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.19586814753520276	[265]	[458,254,202,194]	-3	hSpCas9	negative selection	8422187
43339170	43339193	22	+	27260156	PANC0813	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.5098905645699168	[1067]	[894,809,762,1045]	-6	hSpCas9	negative selection	8422188
43320000	43320023	22	-	27260156	PANC0813	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.5383066720639705	[803]	[1489,1179,1550,1279]	8	hSpCas9	negative selection	8422189
43339221	43339244	22	-	27260156	RDES	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-1.2114658080046574	[38]	[11,23,16,25]	-9	hSpCas9	negative selection	8479184
43291037	43291060	22	+	27260156	RDES	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.10382283448489868	[569]	[587,508,518,851]	-2	hSpCas9	negative selection	8479185
43320000	43320023	22	+	27260156	RDES	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.019874564239931947	[308]	[204,318,357,628]	0	hSpCas9	negative selection	8479186
43291104	43291127	22	+	27260156	RDES	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.33294353543203237	[265]	[122,218,265,412]	-5	hSpCas9	negative selection	8543438
43339170	43339193	22	+	27260156	RDES	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.9483473666669358	[1067]	[611,685,657,556]	-9	hSpCas9	negative selection	8543439
43320000	43320023	22	-	27260156	RDES	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.42011123357434743	[803]	[1115,1118,1327,1413]	6	hSpCas9	negative selection	8543440
43339221	43339244	22	-	27260156	PC3	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.24100427919979373	[38]	[22,21,62,36]	-5	hSpCas9	negative selection	8600435
43291037	43291060	22	+	27260156	PC3	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.1663136933332176	[569]	[349,333,790,694]	-4	hSpCas9	negative selection	8600436
43320000	43320023	22	+	27260156	PC3	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.16126536347303028	[308]	[190,291,610,431]	3	hSpCas9	negative selection	8600437
43291104	43291127	22	+	27260156	PC3	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.2524351514311912	[265]	[119,209,559,155]	-5	hSpCas9	negative selection	8664689
43339170	43339193	22	+	27260156	PC3	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.10304820738890963	[1067]	[534,1515,1332,784]	-2	hSpCas9	negative selection	8664690
43320000	43320023	22	-	27260156	PC3	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.3209134865920139	[803]	[684,848,1952,927]	7	hSpCas9	negative selection	8664691
43339221	43339244	22	-	27260156	PATU8988T	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.6384789362411358	[38]	[116,5,85,16]	9	hSpCas9	negative selection	8721686
43291037	43291060	22	+	27260156	PATU8988T	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.10348534543068055	[569]	[480,495,532,540]	-2	hSpCas9	negative selection	8721687
43320000	43320023	22	+	27260156	PATU8988T	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.18593806226220694	[308]	[447,425,274,207]	3	hSpCas9	negative selection	8721688
43291104	43291127	22	+	27260156	PATU8988T	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.6111486469642754	[265]	[73,174,171,259]	-7	hSpCas9	negative selection	8785940
43339170	43339193	22	+	27260156	PATU8988T	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.28512899481980525	[1067]	[653,1020,855,874]	-5	hSpCas9	negative selection	8785941
43320000	43320023	22	-	27260156	PATU8988T	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.4189883885851965	[803]	[984,1571,980,634]	7	hSpCas9	negative selection	8785942
43339221	43339244	22	-	27260156	T47D	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.27236697927703	[38]	[42,22,59,24]	-5	hSpCas9	negative selection	8842937
43291037	43291060	22	+	27260156	T47D	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.3144476890839465	[569]	[674,494,463,505]	-6	hSpCas9	negative selection	8842938
43320000	43320023	22	+	27260156	T47D	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.09577694722415797	[308]	[329,363,319,330]	-2	hSpCas9	negative selection	8842939
43291104	43291127	22	+	27260156	T47D	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.17243933305274206	[265]	[289,308,298,195]	-4	hSpCas9	negative selection	8907191
43339170	43339193	22	+	27260156	T47D	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.1966670963812993	[1067]	[1088,1048,1016,1194]	-4	hSpCas9	negative selection	8907192
43320000	43320023	22	-	27260156	T47D	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.1281808874681648	[803]	[1017,938,1082,1061]	2	hSpCas9	negative selection	8907193
43339221	43339244	22	-	27260156	SU8686	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.4677781403997301	[38]	[16,23,12,64]	-6	hSpCas9	negative selection	8964188
43291037	43291060	22	+	27260156	SU8686	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.2064266259553661	[569]	[714,539,587,787]	3	hSpCas9	negative selection	8964189
43320000	43320023	22	+	27260156	SU8686	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.0735470830611279	[308]	[345,335,253,348]	1	hSpCas9	negative selection	8964190
43291104	43291127	22	+	27260156	SU8686	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.18439809006718855	[265]	[179,294,184,268]	-3	hSpCas9	negative selection	9028442
43339170	43339193	22	+	27260156	SU8686	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.7144956768815158	[1067]	[561,651,604,787]	-8	hSpCas9	negative selection	9028443
43320000	43320023	22	-	27260156	SU8686	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.3850419827240549	[803]	[758,932,1354,1187]	6	hSpCas9	negative selection	9028444
43339221	43339244	22	-	27260156	SKES1	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.4373089997621076	[38]	[14,59,36,6]	-7	hSpCas9	negative selection	9085439
43291037	43291060	22	+	27260156	SKES1	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.04175073296566889	[569]	[588,576,499,546]	-1	hSpCas9	negative selection	9085440
43320000	43320023	22	+	27260156	SKES1	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	0.14388268582946706	[308]	[419,313,301,331]	3	hSpCas9	negative selection	9085441
43291104	43291127	22	+	27260156	SKES1	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.16287971737558127	[265]	[273,315,211,166]	-4	hSpCas9	negative selection	9149693
43339170	43339193	22	+	27260156	SKES1	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.4089912827424247	[1067]	[825,891,888,627]	-7	hSpCas9	negative selection	9149694
43320000	43320023	22	-	27260156	SKES1	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.2790319814218528	[803]	[1221,1030,894,797]	6	hSpCas9	negative selection	9149695
43339221	43339244	22	-	27260156	TOV112D	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.3599808696567912	[38]	[24,114,49,24]	6	hSpCas9	negative selection	9206690
43291037	43291060	22	+	27260156	TOV112D	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.09501227497890241	[569]	[665,812,449,564]	1	hSpCas9	negative selection	9206691
43320000	43320023	22	+	27260156	TOV112D	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.21745220149880562	[308]	[349,244,236,234]	-4	hSpCas9	negative selection	9206692
43291104	43291127	22	+	27260156	TOV112D	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.5122931272703964	[265]	[165,213,156,213]	-7	hSpCas9	negative selection	9270944
43339170	43339193	22	+	27260156	TOV112D	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.6131173175302977	[1067]	[736,933,665,524]	-8	hSpCas9	negative selection	9270945
43320000	43320023	22	-	27260156	TOV112D	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.22543422785212597	[803]	[914,1336,835,775]	4	hSpCas9	negative selection	9270946
43339221	43339244	22	-	27260156	TC71	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	-0.61483022559141	[38]	[4,19,23,62]	-9	hSpCas9	negative selection	9327941
43291037	43291060	22	+	27260156	TC71	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.13280265755912946	[569]	[514,570,466,687]	-3	hSpCas9	negative selection	9327942
43320000	43320023	22	+	27260156	TC71	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.146274951629634	[308]	[312,289,224,375]	-4	hSpCas9	negative selection	9327943
43291104	43291127	22	+	27260156	TC71	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.24629557110291211	[265]	[264,267,155,276]	-6	hSpCas9	negative selection	9392195
43339170	43339193	22	+	27260156	TC71	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.10300238725345667	[1067]	[1058,1111,859,1250]	-3	hSpCas9	negative selection	9392196
43320000	43320023	22	-	27260156	TC71	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	-0.06888636089870581	[803]	[781,814,806,887]	-2	hSpCas9	negative selection	9392197
43339221	43339244	22	-	27260156	TC32	viability	ACCCACAGGGTCAGTCGACGTGG	SCUBE1	ENSG00000159307	0.021212249646789694	[38]	[41,31,31,40]	0	hSpCas9	negative selection	9449192
43291037	43291060	22	+	27260156	TC32	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.12822435490065873	[569]	[609,360,550,448]	-2	hSpCas9	negative selection	9449193
43320000	43320023	22	+	27260156	TC32	viability	CCGGGATGTTGATGCACTCGTGG	SCUBE1	ENSG00000159307	-0.4370762033027016	[308]	[228,95,346,241]	-7	hSpCas9	negative selection	9449194
43291104	43291127	22	+	27260156	TC32	viability	CTGACACTCGTAGCTGCCCATGG	SCUBE1	ENSG00000159307	-0.576229067781585	[265]	[145,117,187,237]	-8	hSpCas9	negative selection	9513446
43339170	43339193	22	+	27260156	TC32	viability	TCTGACAGATGGCATCGATGTGG	SCUBE1	ENSG00000159307	-0.5771626311203041	[1067]	[674,536,778,730]	-8	hSpCas9	negative selection	9513447
43320000	43320023	22	-	27260156	TC32	viability	CCACGAGTGCATCAACATCCCGG	SCUBE1	ENSG00000159307	0.30229079293969285	[803]	[995,777,948,1000]	5	hSpCas9	negative selection	9513448
43255498	43255521	22	-	27869803	HPAFII	viability after 27 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.46240416011187246	[691]	[497,503,NaN]	4	hSpCas9	negative selection	9581247
43258233	43258256	22	-	27869803	HPAFII	viability after 27 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.7311599724850004	[154]	[53,44,NaN]	-5	hSpCas9	negative selection	9581248
43291034	43291057	22	+	27869803	HPAFII	viability after 27 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	0.20709183292426359	[400]	[208,271,NaN]	1	hSpCas9	negative selection	9581249
43319951	43319974	22	-	27869803	HPAFII	viability after 27 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	1.1181311283099726	[234]	[439,124,NaN]	8	hSpCas9	negative selection	9581250
43339159	43339182	22	+	27869803	HPAFII	viability after 27 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.5270425247919749	[248]	[198,179,NaN]	4	hSpCas9	negative selection	9581251
43343249	43343272	22	-	27869803	HPAFII	viability after 27 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	1.9569453736347429	[125]	[344,183,NaN]	9	hSpCas9	negative selection	9581252
43255498	43255521	22	-	27869803	HPAFII	viability after 15 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.20656104525751373	[691]	[991,774,NaN]	2	hSpCas9	negative selection	9663696
43258233	43258256	22	-	27869803	HPAFII	viability after 15 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.4458139270686996	[154]	[125,119,NaN]	-5	hSpCas9	negative selection	9663697
43291034	43291057	22	+	27869803	HPAFII	viability after 15 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	0.326732245085246	[400]	[595,505,NaN]	4	hSpCas9	negative selection	9663698
43319951	43319974	22	-	27869803	HPAFII	viability after 15 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	1.2593518406645363	[234]	[804,479,NaN]	9	hSpCas9	negative selection	9663699
43339159	43339182	22	+	27869803	HPAFII	viability after 15 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.23872325137823508	[248]	[279,337,NaN]	2	hSpCas9	negative selection	9663700
43343249	43343272	22	-	27869803	HPAFII	viability after 15 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	1.3835621048805902	[125]	[697,138,NaN]	9	hSpCas9	negative selection	9663701
43255498	43255521	22	-	27869803	ASPC1	viability after 36 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.18329987130367043	[1645]	[462,948,542]	1	hSpCas9	negative selection	9746145
43258233	43258256	22	-	27869803	ASPC1	viability after 36 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	0.2727636685734832	[353]	[17,269,143]	2	hSpCas9	negative selection	9746146
43291034	43291057	22	+	27869803	ASPC1	viability after 36 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	0.31412896045045247	[964]	[690,373,258]	3	hSpCas9	negative selection	9746147
43319951	43319974	22	-	27869803	ASPC1	viability after 36 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.24702008392546526	[1106]	[418,292,612]	2	hSpCas9	negative selection	9746148
43339159	43339182	22	+	27869803	ASPC1	viability after 36 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.13133193966315077	[618]	[456,147,149]	1	hSpCas9	negative selection	9746149
43343249	43343272	22	-	27869803	ASPC1	viability after 36 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	1.4617704547287798	[391]	[22,186,771]	9	hSpCas9	negative selection	9746150
43255498	43255521	22	-	27869803	PATU8988S	viability after 35 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	-0.11741515709352757	[1380]	[391,633,NaN]	-1	hSpCas9	negative selection	9828594
43258233	43258256	22	-	27869803	PATU8988S	viability after 35 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.0790535094390028	[344]	[148,113,NaN]	-1	hSpCas9	negative selection	9828595
43291034	43291057	22	+	27869803	PATU8988S	viability after 35 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.41081061683377723	[923]	[246,312,NaN]	-4	hSpCas9	negative selection	9828596
43319951	43319974	22	-	27869803	PATU8988S	viability after 35 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	-0.07608562578624889	[1073]	[336,483,NaN]	-1	hSpCas9	negative selection	9828597
43339159	43339182	22	+	27869803	PATU8988S	viability after 35 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.11492474493492283	[467]	[254,152,NaN]	1	hSpCas9	negative selection	9828598
43343249	43343272	22	-	27869803	PATU8988S	viability after 35 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	-0.11686759207020347	[342]	[80,173,NaN]	-1	hSpCas9	negative selection	9828599
43255498	43255521	22	-	27869803	PATU8988S	viability after 31 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.12081913942303024	[1380]	[435,805,NaN]	1	hSpCas9	negative selection	9911043
43258233	43258256	22	-	27869803	PATU8988S	viability after 31 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	0.0506375984645302	[344]	[145,137,NaN]	0	hSpCas9	negative selection	9911044
43291034	43291057	22	+	27869803	PATU8988S	viability after 31 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	-0.46328773759384084	[923]	[268,264,NaN]	-5	hSpCas9	negative selection	9911045
43319951	43319974	22	-	27869803	PATU8988S	viability after 31 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	0.07720185846702043	[1073]	[215,751,NaN]	1	hSpCas9	negative selection	9911046
43339159	43339182	22	+	27869803	PATU8988S	viability after 31 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.20859500603560976	[467]	[223,204,NaN]	2	hSpCas9	negative selection	9911047
43343249	43343272	22	-	27869803	PATU8988S	viability after 31 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	-0.7486969516039838	[342]	[65,100,NaN]	-7	hSpCas9	negative selection	9911048
43255498	43255521	22	-	27869803	HPAFII	viability after 35 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.7546869002150598	[691]	[409,794,NaN]	5	hSpCas9	negative selection	9993492
43258233	43258256	22	-	27869803	HPAFII	viability after 35 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.45236895908303043	[154]	[46,68,NaN]	-3	hSpCas9	negative selection	9993493
43291034	43291057	22	+	27869803	HPAFII	viability after 35 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	0.19614617798963718	[400]	[74,409,NaN]	1	hSpCas9	negative selection	9993494
43319951	43319974	22	-	27869803	HPAFII	viability after 35 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	1.9590969103704459	[234]	[661,237,NaN]	9	hSpCas9	negative selection	9993495
43339159	43339182	22	+	27869803	HPAFII	viability after 35 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.5506295265874497	[248]	[162,208,NaN]	3	hSpCas9	negative selection	9993496
43343249	43343272	22	-	27869803	HPAFII	viability after 35 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	2.0815819862852236	[125]	[253,287,NaN]	9	hSpCas9	negative selection	9993497
43255498	43255521	22	-	27869803	HPAFII	viability after 31 days	TGGACAAGCGGGTGAAACGGCGG	SCUBE1	ENSG00000159307	0.40609066871607613	[691]	[438,596,NaN]	3	hSpCas9	negative selection	10075941
43258233	43258256	22	-	27869803	HPAFII	viability after 31 days	AAGTACGCCCTCCACTCAGACGG	SCUBE1	ENSG00000159307	-0.27698479698633516	[154]	[55,88,NaN]	-2	hSpCas9	negative selection	10075942
43291034	43291057	22	+	27869803	HPAFII	viability after 31 days	GGCTGTACTCACCATTGGAGCGG	SCUBE1	ENSG00000159307	0.0685558225821784	[400]	[101,381,NaN]	0	hSpCas9	negative selection	10075943
43319951	43319974	22	-	27869803	HPAFII	viability after 31 days	GGCTTCATGCTGGCACACGATGG	SCUBE1	ENSG00000159307	1.5009631340036713	[234]	[412,329,NaN]	9	hSpCas9	negative selection	10075944
43339159	43339182	22	+	27869803	HPAFII	viability after 31 days	CTTGGGCGTGTTCTGACAGATGG	SCUBE1	ENSG00000159307	0.40814458624727507	[248]	[183,186,NaN]	3	hSpCas9	negative selection	10075945
43343249	43343272	22	-	27869803	HPAFII	viability after 31 days	CGCATTGAGCATGGGCGCGGCGG	SCUBE1	ENSG00000159307	1.6544010586299382	[125]	[235,207,NaN]	9	hSpCas9	negative selection	10075946
43231845	43231868	22	-	28162770	P31FUJ	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	-1.3279594374547188	[187]	[87]	-7	hSpCas9	negative selection	10230919
43229071	43229094	22	-	28162770	P31FUJ	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-1.7563641604713913	[45]	[15]	-8	hSpCas9	negative selection	10230920
43208151	43208174	22	+	28162770	P31FUJ	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-1.6207278580759812	[122]	[46]	-7	hSpCas9	negative selection	10230921
43291150	43291173	22	-	28162770	P31FUJ	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	-0.25333913541707326	[282]	[278]	-2	hSpCas9	negative selection	10230922
43291121	43291144	22	-	28162770	P31FUJ	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	-0.06161555440815514	[126]	[142]	0	hSpCas9	negative selection	10230923
43291037	43291060	22	+	28162770	P31FUJ	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.4505029304261044	[306]	[263]	-4	hSpCas9	negative selection	10230924
43262774	43262797	22	-	28162770	P31FUJ	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-3.440397623822746	[193]	[20]	-9	hSpCas9	negative selection	10230925
43229115	43229138	22	+	28162770	P31FUJ	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	-0.5584406186401156	[291]	[232]	-5	hSpCas9	negative selection	10230926
43231845	43231868	22	-	28162770	TF1	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10400285
43229071	43229094	22	-	28162770	TF1	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10400286
43208151	43208174	22	+	28162770	TF1	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10400287
43291150	43291173	22	-	28162770	TF1	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	NaN	[NaN]	[207]	1	hSpCas9	negative selection	10400288
43291121	43291144	22	-	28162770	TF1	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	NaN	[NaN]	[125]	1	hSpCas9	negative selection	10400289
43291037	43291060	22	+	28162770	TF1	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10400290
43262774	43262797	22	-	28162770	TF1	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10400291
43229115	43229138	22	+	28162770	TF1	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10400292
43231845	43231868	22	-	28162770	SKM1	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	0.8016931971878651	[48]	[150]	7	hSpCas9	negative selection	10569651
43229071	43229094	22	-	28162770	SKM1	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-3.991926699464318	[17]	[1]	-9	hSpCas9	negative selection	10569652
43208151	43208174	22	+	28162770	SKM1	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-3.4367115421372136	[48]	[7]	-9	hSpCas9	negative selection	10569653
43291150	43291173	22	-	28162770	SKM1	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	-0.22862695748464912	[113]	[171]	-2	hSpCas9	negative selection	10569654
43291121	43291144	22	-	28162770	SKM1	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	0.2876227931524926	[37]	[81]	3	hSpCas9	negative selection	10569655
43291037	43291060	22	+	28162770	SKM1	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.8146229225216433	[63]	[198]	7	hSpCas9	negative selection	10569656
43262774	43262797	22	-	28162770	SKM1	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-5.494427039993501	[50]	[1]	-9	hSpCas9	negative selection	10569657
43229115	43229138	22	+	28162770	SKM1	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	0.7700155602331011	[67]	[204]	7	hSpCas9	negative selection	10569658
43231845	43231868	22	-	28162770	SKM1	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	0.8016931971878651	[48]	[150]	7	hSpCas9	negative selection	10739017
43229071	43229094	22	-	28162770	SKM1	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-3.991926699464318	[17]	[1]	-9	hSpCas9	negative selection	10739018
43208151	43208174	22	+	28162770	SKM1	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-3.4367115421372136	[48]	[7]	-9	hSpCas9	negative selection	10739019
43291150	43291173	22	-	28162770	SKM1	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	-0.22862695748464912	[113]	[171]	-2	hSpCas9	negative selection	10739020
43291121	43291144	22	-	28162770	SKM1	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	0.2876227931524926	[37]	[81]	3	hSpCas9	negative selection	10739021
43291037	43291060	22	+	28162770	SKM1	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.8146229225216433	[63]	[198]	7	hSpCas9	negative selection	10739022
43262774	43262797	22	-	28162770	SKM1	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-5.494427039993501	[50]	[1]	-9	hSpCas9	negative selection	10739023
43229115	43229138	22	+	28162770	SKM1	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	0.7700155602331011	[67]	[204]	7	hSpCas9	negative selection	10739024
43231845	43231868	22	-	28162770	PL21	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	0.17822483806087944	[198]	[97]	1	hSpCas9	negative selection	10908383
43229071	43229094	22	-	28162770	PL21	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-0.2592920041479774	[10]	[3]	-2	hSpCas9	negative selection	10908384
43208151	43208174	22	+	28162770	PL21	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-2.486360912693898	[102]	[7]	-9	hSpCas9	negative selection	10908385
43291150	43291173	22	-	28162770	PL21	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	0.26513686933575586	[433]	[226]	2	hSpCas9	negative selection	10908386
43291121	43291144	22	-	28162770	PL21	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	-0.3198674443910663	[151]	[52]	-2	hSpCas9	negative selection	10908387
43291037	43291060	22	+	28162770	PL21	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.06920856527667599	[228]	[94]	0	hSpCas9	negative selection	10908388
43262774	43262797	22	-	28162770	PL21	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-2.310822304788059	[170]	[14]	-8	hSpCas9	negative selection	10908389
43229115	43229138	22	+	28162770	PL21	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	0.4376389282159765	[284]	[167]	4	hSpCas9	negative selection	10908390
43231845	43231868	22	-	28162770	P31FUJ	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	-1.3279594374547188	[187]	[87]	-7	hSpCas9	negative selection	11077749
43229071	43229094	22	-	28162770	P31FUJ	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-1.7563641604713913	[45]	[15]	-8	hSpCas9	negative selection	11077750
43208151	43208174	22	+	28162770	P31FUJ	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-1.6207278580759812	[122]	[46]	-7	hSpCas9	negative selection	11077751
43291150	43291173	22	-	28162770	P31FUJ	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	-0.25333913541707326	[282]	[278]	-2	hSpCas9	negative selection	11077752
43291121	43291144	22	-	28162770	P31FUJ	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	-0.06161555440815514	[126]	[142]	0	hSpCas9	negative selection	11077753
43291037	43291060	22	+	28162770	P31FUJ	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.4505029304261044	[306]	[263]	-4	hSpCas9	negative selection	11077754
43262774	43262797	22	-	28162770	P31FUJ	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-3.440397623822746	[193]	[20]	-9	hSpCas9	negative selection	11077755
43229115	43229138	22	+	28162770	P31FUJ	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	-0.5584406186401156	[291]	[232]	-5	hSpCas9	negative selection	11077756
43231845	43231868	22	-	28162770	OCIAML5	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	1.1240866871816355	[60]	[239]	8	hSpCas9	negative selection	11247115
43229071	43229094	22	-	28162770	OCIAML5	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	1.810898441858432	[2]	[18]	9	hSpCas9	negative selection	11247116
43208151	43208174	22	+	28162770	OCIAML5	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-2.2870036275805457	[72]	[26]	-8	hSpCas9	negative selection	11247117
43291150	43291173	22	-	28162770	OCIAML5	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	0.5640768656410159	[162]	[434]	5	hSpCas9	negative selection	11247118
43291121	43291144	22	-	28162770	OCIAML5	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	0.2682276628537148	[68]	[149]	2	hSpCas9	negative selection	11247119
43291037	43291060	22	+	28162770	OCIAML5	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.37428386404113423	[155]	[364]	3	hSpCas9	negative selection	11247120
43262774	43262797	22	-	28162770	OCIAML5	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-4.502320531836872	[112]	[8]	-9	hSpCas9	negative selection	11247121
43229115	43229138	22	+	28162770	OCIAML5	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	-1.6521290003552451	[147]	[84]	-7	hSpCas9	negative selection	11247122
43231845	43231868	22	-	28162770	EOL1	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	0.4859234519740748	[369]	[272]	4	hSpCas9	negative selection	11416481
43229071	43229094	22	-	28162770	EOL1	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-0.07545222842946542	[29]	[14]	0	hSpCas9	negative selection	11416482
43208151	43208174	22	+	28162770	EOL1	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-2.1260783014994336	[173]	[20]	-8	hSpCas9	negative selection	11416483
43291150	43291173	22	-	28162770	EOL1	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	-0.4267812397573869	[693]	[271]	-3	hSpCas9	negative selection	11416484
43291121	43291144	22	-	28162770	EOL1	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	0.4770887945993132	[269]	[197]	4	hSpCas9	negative selection	11416485
43291037	43291060	22	+	28162770	EOL1	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.7404971655384686	[525]	[462]	6	hSpCas9	negative selection	11416486
43262774	43262797	22	-	28162770	EOL1	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-4.630041080107103	[234]	[4]	-9	hSpCas9	negative selection	11416487
43229115	43229138	22	+	28162770	EOL1	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	0.09803059242603601	[359]	[202]	0	hSpCas9	negative selection	11416488
43231845	43231868	22	-	28162770	MOLM13	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	1.0549503481497329	[228]	[343]	7	hSpCas9	negative selection	11585847
43229071	43229094	22	-	28162770	MOLM13	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-0.8760650196727822	[32]	[12]	-5	hSpCas9	negative selection	11585848
43208151	43208174	22	+	28162770	MOLM13	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-2.0928255729299003	[176]	[29]	-7	hSpCas9	negative selection	11585849
43291150	43291173	22	-	28162770	MOLM13	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	0.261872789161976	[510]	[442]	2	hSpCas9	negative selection	11585850
43291121	43291144	22	-	28162770	MOLM13	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	0.947439642378151	[245]	[342]	7	hSpCas9	negative selection	11585851
43291037	43291060	22	+	28162770	MOLM13	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.3123196730793367	[449]	[403]	2	hSpCas9	negative selection	11585852
43262774	43262797	22	-	28162770	MOLM13	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-5.365000632620164	[227]	[3]	-9	hSpCas9	negative selection	11585853
43229115	43229138	22	+	28162770	MOLM13	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	-1.0522219748266095	[260]	[90]	-5	hSpCas9	negative selection	11585854
43231845	43231868	22	-	28162770	HEL	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	-0.34612061039444264	[257]	[129]	-2	hSpCas9	negative selection	11755213
43229071	43229094	22	-	28162770	HEL	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-0.48654418494460927	[34]	[15]	-3	hSpCas9	negative selection	11755214
43208151	43208174	22	+	28162770	HEL	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-2.0866135780559745	[125]	[18]	-8	hSpCas9	negative selection	11755215
43291150	43291173	22	-	28162770	HEL	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	-0.5080411201752522	[523]	[235]	-3	hSpCas9	negative selection	11755216
43291121	43291144	22	-	28162770	HEL	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	1.0925417494398775	[204]	[279]	8	hSpCas9	negative selection	11755217
43291037	43291060	22	+	28162770	HEL	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	-0.008835270935204531	[409]	[260]	0	hSpCas9	negative selection	11755218
43262774	43262797	22	-	28162770	HEL	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-7.270150504229605	[240]	[0]	-9	hSpCas9	negative selection	11755219
43229115	43229138	22	+	28162770	HEL	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	0.008866730798254258	[224]	[144]	0	hSpCas9	negative selection	11755220
43231845	43231868	22	-	28162770	MV411	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	-0.6129563819216428	[186]	[102]	-4	hSpCas9	negative selection	11924579
43229071	43229094	22	-	28162770	MV411	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	1.2089634029681395	[18]	[36]	9	hSpCas9	negative selection	11924580
43208151	43208174	22	+	28162770	MV411	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-2.7036528487362785	[115]	[14]	-9	hSpCas9	negative selection	11924581
43291150	43291173	22	-	28162770	MV411	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	-0.14160473996312395	[329]	[251]	-1	hSpCas9	negative selection	11924582
43291121	43291144	22	-	28162770	MV411	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	0.3201938932180895	[173]	[182]	3	hSpCas9	negative selection	11924583
43291037	43291060	22	+	28162770	MV411	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.7531733603533561	[261]	[371]	6	hSpCas9	negative selection	11924584
43262774	43262797	22	-	28162770	MV411	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-5.902309568721907	[141]	[1]	-9	hSpCas9	negative selection	11924585
43229115	43229138	22	+	28162770	MV411	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	-0.35256883016283075	[240]	[158]	-3	hSpCas9	negative selection	11924586
43231845	43231868	22	-	28162770	MONOMAC1	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	-0.3092463506455787	[146]	[135]	-3	hSpCas9	negative selection	12093945
43229071	43229094	22	-	28162770	MONOMAC1	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	3.110391678132694	[9]	[98]	9	hSpCas9	negative selection	12093946
43208151	43208174	22	+	28162770	MONOMAC1	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-4.6727702780259515	[88]	[3]	-9	hSpCas9	negative selection	12093947
43291150	43291173	22	-	28162770	MONOMAC1	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	-0.1049762940707859	[257]	[274]	-1	hSpCas9	negative selection	12093948
43291121	43291144	22	-	28162770	MONOMAC1	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	0.44491563224643194	[90]	[141]	4	hSpCas9	negative selection	12093949
43291037	43291060	22	+	28162770	MONOMAC1	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.10976996080314572	[210]	[260]	1	hSpCas9	negative selection	12093950
43262774	43262797	22	-	28162770	MONOMAC1	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-3.31251406447949	[103]	[11]	-9	hSpCas9	negative selection	12093951
43229115	43229138	22	+	28162770	MONOMAC1	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	-0.24342975254400512	[157]	[152]	-2	hSpCas9	negative selection	12093952
43231845	43231868	22	-	28162770	OCIAML2	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	-0.0218717081193162	[36]	[201]	0	hSpCas9	negative selection	12263311
43229071	43229094	22	-	28162770	OCIAML2	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-0.030057233856179977	[6]	[37]	0	hSpCas9	negative selection	12263312
43208151	43208174	22	+	28162770	OCIAML2	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-2.074701148911022	[18]	[24]	-8	hSpCas9	negative selection	12263313
43291150	43291173	22	-	28162770	OCIAML2	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	-0.24823740390571336	[77]	[363]	-2	hSpCas9	negative selection	12263314
43291121	43291144	22	-	28162770	OCIAML2	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	0.014797001928080478	[39]	[223]	0	hSpCas9	negative selection	12263315
43291037	43291060	22	+	28162770	OCIAML2	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.0006758936834277973	[54]	[304]	0	hSpCas9	negative selection	12263316
43262774	43262797	22	-	28162770	OCIAML2	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-4.903589232518267	[26]	[4]	-9	hSpCas9	negative selection	12263317
43229115	43229138	22	+	28162770	OCIAML2	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	-0.13805448615529053	[26]	[135]	-1	hSpCas9	negative selection	12263318
43231845	43231868	22	-	28162770	OCIAML3	viability	GAGTGCCTGGTCAACAACGGAGG	SCUBE1	ENSG00000159307	-0.6421019285252081	[60]	[117]	-5	hSpCas9	negative selection	12432677
43229071	43229094	22	-	28162770	OCIAML3	viability	TACGGGACAACCCACTGCGGAGG	SCUBE1	ENSG00000159307	-1.4013625623817676	[6]	[7]	-7	hSpCas9	negative selection	12432678
43208151	43208174	22	+	28162770	OCIAML3	viability	GGAGCGGGAGGTGAAGGCGATGG	SCUBE1	ENSG00000159307	-2.553365655826817	[34]	[17]	-9	hSpCas9	negative selection	12432679
43291150	43291173	22	-	28162770	OCIAML3	viability	GAGTGTCAGGACAATAATGGTGG	SCUBE1	ENSG00000159307	-1.404973815934146	[99]	[113]	-7	hSpCas9	negative selection	12432680
43291121	43291144	22	-	28162770	OCIAML3	viability	GCAGATCTGCGTCAATGCCATGG	SCUBE1	ENSG00000159307	-0.07775788968702119	[42]	[122]	0	hSpCas9	negative selection	12432681
43291037	43291060	22	+	28162770	OCIAML3	viability	TGTACTCACCATTGGAGCGGTGG	SCUBE1	ENSG00000159307	0.8556030075021069	[66]	[365]	7	hSpCas9	negative selection	12432682
43262774	43262797	22	-	28162770	OCIAML3	viability	GGAGACGCCCAAAGGTGGGGTGG	SCUBE1	ENSG00000159307	-2.5659932641545664	[50]	[25]	-9	hSpCas9	negative selection	12432683
43229115	43229138	22	+	28162770	OCIAML3	viability	CAGGCACTGGAAGCTGCCCGGGG	SCUBE1	ENSG00000159307	0.7635443642939204	[39]	[204]	7	hSpCas9	negative selection	12432684