Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:222663
• Symbol:SCUBE3
• Description:signal peptide, CUB domain and EGF like domain containing 3

DataSource: http://genomecrispr.dkfz.de/#!/results/SCUBE3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
35227681	35227704	6	+	26472758	Jiyoye	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	-0.26820241443750104	[213]	[133]	-2	hSpCas9	negative selection	143371
35242274	35242297	6	+	26472758	Jiyoye	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	-0.56367827283461	[146]	[74]	-4	hSpCas9	negative selection	143372
35244687	35244710	6	-	26472758	Jiyoye	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	1.4071753815058734	[58]	[117]	8	hSpCas9	negative selection	143373
35227625	35227648	6	+	26472758	Jiyoye	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	1.6366572276286406	[57]	[135]	8	hSpCas9	negative selection	143374
35231724	35231747	6	+	26472758	Jiyoye	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	0.7612838821423856	[132]	[169]	5	hSpCas9	negative selection	143375
35232875	35232898	6	-	26472758	Jiyoye	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	1.9921378822270295	[10]	[32]	8	hSpCas9	negative selection	143376
35233265	35233288	6	+	26472758	Jiyoye	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.8477479728918547	[83]	[113]	6	hSpCas9	negative selection	143377
35241146	35241169	6	+	26472758	Jiyoye	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	-0.027761675210675296	[218]	[161]	0	hSpCas9	negative selection	143378
35241550	35241573	6	+	26472758	Jiyoye	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-0.6679260737348451	[275]	[130]	-5	hSpCas9	negative selection	143379
35241900	35241923	6	-	26472758	Jiyoye	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	0.5658731275249316	[42]	[47]	4	hSpCas9	negative selection	143380
35227681	35227704	6	+	26472758	KBM7	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	0.6500947531163805	[648,701]	[637,381]	7	hSpCas9	negative selection	334489
35242274	35242297	6	+	26472758	KBM7	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	-0.3053867841029875	[600,669]	[209,274]	-3	hSpCas9	negative selection	334490
35244687	35244710	6	-	26472758	KBM7	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	-0.7379499384160301	[653,347]	[89,179]	-6	hSpCas9	negative selection	334491
35227625	35227648	6	+	26472758	KBM7	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	-0.17162996578202688	[420,293]	[217,83]	-2	hSpCas9	negative selection	334492
35231724	35231747	6	+	26472758	KBM7	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	0.6819301761109409	[1047,934]	[790,707]	7	hSpCas9	negative selection	334493
35232875	35232898	6	-	26472758	KBM7	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	0.5580913379116466	[132,55]	[109,20]	6	hSpCas9	negative selection	334494
35233265	35233288	6	+	26472758	KBM7	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.3409950546942011	[491,567]	[262,369]	3	hSpCas9	negative selection	334495
35241146	35241169	6	+	26472758	KBM7	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	0.21747066888237707	[460,387]	[265,199]	2	hSpCas9	negative selection	334496
35241550	35241573	6	+	26472758	KBM7	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-0.4479422276977514	[1215,1387]	[302,588]	-4	hSpCas9	negative selection	334497
35241900	35241923	6	-	26472758	KBM7	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	0.11068025558031114	[338,346]	[114,228]	1	hSpCas9	negative selection	334498
35227681	35227704	6	+	26472758	Raji	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	0.555479323231739	[301]	[102]	5	hSpCas9	negative selection	525607
35242274	35242297	6	+	26472758	Raji	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	0.5782742693859607	[227]	[78]	5	hSpCas9	negative selection	525608
35244687	35244710	6	-	26472758	Raji	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	0.7137196868873227	[133]	[50]	6	hSpCas9	negative selection	525609
35227625	35227648	6	+	26472758	Raji	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	1.1524714249021377	[125]	[64]	8	hSpCas9	negative selection	525610
35231724	35231747	6	+	26472758	Raji	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	0.2715029151347062	[331]	[92]	2	hSpCas9	negative selection	525611
35232875	35232898	6	-	26472758	Raji	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	2.027213186689616	[36]	[34]	9	hSpCas9	negative selection	525612
35233265	35233288	6	+	26472758	Raji	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.053081136819646546	[379]	[84]	0	hSpCas9	negative selection	525613
35241146	35241169	6	+	26472758	Raji	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	0.7891124640943261	[196]	[78]	7	hSpCas9	negative selection	525614
35241550	35241573	6	+	26472758	Raji	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-1.5073263087416087	[538]	[43]	-8	hSpCas9	negative selection	525615
35241900	35241923	6	-	26472758	Raji	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	0.37041794120739346	[129]	[38]	3	hSpCas9	negative selection	525616
35227681	35227704	6	+	26472758	K562	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	-0.10411662202234329	[642]	[504]	0	hSpCas9	negative selection	716725
35242274	35242297	6	+	26472758	K562	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	0.3688385623015631	[432]	[471]	3	hSpCas9	negative selection	716726
35244687	35244710	6	-	26472758	K562	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	-0.3739023700011402	[349]	[227]	-2	hSpCas9	negative selection	716727
35227625	35227648	6	+	26472758	K562	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.437898457087656	[215]	[246]	3	hSpCas9	negative selection	716728
35231724	35231747	6	+	26472758	K562	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	-0.7714837669261818	[820]	[405]	-4	hSpCas9	negative selection	716729
35232875	35232898	6	-	26472758	K562	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	0.8076861572882839	[66]	[98]	6	hSpCas9	negative selection	716730
35233265	35233288	6	+	26472758	K562	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.5255294237403751	[422]	[513]	4	hSpCas9	negative selection	716731
35241146	35241169	6	+	26472758	K562	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	-0.5170258425853238	[316]	[186]	-3	hSpCas9	negative selection	716732
35241550	35241573	6	+	26472758	K562	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-2.0501512516004534	[887]	[180]	-7	hSpCas9	negative selection	716733
35241900	35241923	6	-	26472758	K562	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	0.04251568186295457	[267]	[232]	0	hSpCas9	negative selection	716734
35214482	35214505	6	+	26627737	DLD1	viability	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.33295920531723067	[637]	[342,379,64]	3	hSpCas9	negative selection	832518
35228615	35228638	6	+	26627737	DLD1	viability	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.06768879124132399	[984]	[357,259,343]	0	hSpCas9	negative selection	832519
35231790	35231813	6	+	26627737	DLD1	viability	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	0.8029283541572549	[261]	[121,195,116]	7	hSpCas9	negative selection	832520
35232892	35232915	6	+	26627737	DLD1	viability	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.22902161184715225	[616]	[174,351,165]	2	hSpCas9	negative selection	832521
35233265	35233288	6	+	26627737	DLD1	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.23797261426732774	[470]	[199,240,94]	2	hSpCas9	negative selection	832522
35237903	35237926	6	+	26627737	DLD1	viability	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.1985731783168394	[830]	[423,256,222]	2	hSpCas9	negative selection	832523
35214482	35214505	6	+	26627737	GBM cells	viability after 5 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	-0.13008599683686672	[401]	[179,213]	-2	hSpCas9	negative selection	914833
35228615	35228638	6	+	26627737	GBM cells	viability after 5 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.2248550322796714	[358]	[239,209]	3	hSpCas9	negative selection	914834
35231790	35231813	6	+	26627737	GBM cells	viability after 5 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-0.8380517192805208	[124]	[44,29]	-8	hSpCas9	negative selection	914835
35232892	35232915	6	+	26627737	GBM cells	viability after 5 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.1527965823499493	[368]	[258,180]	2	hSpCas9	negative selection	914836
35233265	35233288	6	+	26627737	GBM cells	viability after 5 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.11320968419680391	[238]	[111,124]	-2	hSpCas9	negative selection	914837
35237903	35237926	6	+	26627737	GBM cells	viability after 5 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.11610909215725318	[436]	[312,194]	1	hSpCas9	negative selection	914838
35214482	35214505	6	+	26627737	GBM cells	viability after 13 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	-0.21808863410213425	[401]	[181,191]	-3	hSpCas9	negative selection	997148
35228615	35228638	6	+	26627737	GBM cells	viability after 13 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.17928275661178128	[358]	[235,207]	2	hSpCas9	negative selection	997149
35231790	35231813	6	+	26627737	GBM cells	viability after 13 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-1.2348741447317695	[124]	[3,48]	-8	hSpCas9	negative selection	997150
35232892	35232915	6	+	26627737	GBM cells	viability after 13 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.22453743031533335	[368]	[298,180]	3	hSpCas9	negative selection	997151
35233265	35233288	6	+	26627737	GBM cells	viability after 13 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.20923196618662204	[238]	[104,117]	-3	hSpCas9	negative selection	997152
35237903	35237926	6	+	26627737	GBM cells	viability after 13 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.09791947067483642	[436]	[325,194]	1	hSpCas9	negative selection	997153
35214482	35214505	6	+	26627737	GBM cells	viability after 21 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.08688619872757397	[401]	[232,230]	0	hSpCas9	negative selection	1079463
35228615	35228638	6	+	26627737	GBM cells	viability after 21 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.46164907948212375	[358]	[289,248]	5	hSpCas9	negative selection	1079464
35231790	35231813	6	+	26627737	GBM cells	viability after 21 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-1.0835486321352807	[124]	[30,32]	-7	hSpCas9	negative selection	1079465
35232892	35232915	6	+	26627737	GBM cells	viability after 21 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.4734261801955211	[368]	[293,263]	5	hSpCas9	negative selection	1079466
35233265	35233288	6	+	26627737	GBM cells	viability after 21 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.42535530315423536	[238]	[103,89]	-4	hSpCas9	negative selection	1079467
35237903	35237926	6	+	26627737	GBM cells	viability after 21 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.049954498907454736	[436]	[250,240]	0	hSpCas9	negative selection	1079468
35214482	35214505	6	+	26627737	RPE1	viability after 9 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.4469762170499655	[1539]	[768,512]	3	hSpCas9	negative selection	1161778
35228615	35228638	6	+	26627737	RPE1	viability after 9 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	-0.9179702418245033	[1373]	[183,283]	-6	hSpCas9	negative selection	1161779
35231790	35231813	6	+	26627737	RPE1	viability after 9 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-2.635716006972253	[691]	[26,44]	-9	hSpCas9	negative selection	1161780
35232892	35232915	6	+	26627737	RPE1	viability after 9 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	1.7968620678228033	[341]	[385,353]	8	hSpCas9	negative selection	1161781
35233265	35233288	6	+	26627737	RPE1	viability after 9 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.6275481537044867	[595]	[101,144]	-4	hSpCas9	negative selection	1161782
35237903	35237926	6	+	26627737	RPE1	viability after 9 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	1.011501256189117	[1098]	[697,687]	6	hSpCas9	negative selection	1161783
35214482	35214505	6	+	26627737	RPE1	viability after 12 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.5561376100713936	[1539]	[755,451]	3	hSpCas9	negative selection	1244093
35228615	35228638	6	+	26627737	RPE1	viability after 12 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	-0.041133684235631796	[1373]	[469,240]	0	hSpCas9	negative selection	1244094
35231790	35231813	6	+	26627737	RPE1	viability after 12 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-1.563856403016996	[691]	[75,48]	-8	hSpCas9	negative selection	1244095
35232892	35232915	6	+	26627737	RPE1	viability after 12 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	1.668648000789268	[341]	[278,305]	8	hSpCas9	negative selection	1244096
35233265	35233288	6	+	26627737	RPE1	viability after 12 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.3121494225421542	[595]	[144,111]	-2	hSpCas9	negative selection	1244097
35237903	35237926	6	+	26627737	RPE1	viability after 12 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	1.0152394660917823	[1098]	[759,423]	6	hSpCas9	negative selection	1244098
35214482	35214505	6	+	26627737	RPE1	viability after 15 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	-0.16265992306379395	[1539]	[406,371]	-1	hSpCas9	negative selection	1326408
35228615	35228638	6	+	26627737	RPE1	viability after 15 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	-0.12305778571279713	[1373]	[418,296]	-1	hSpCas9	negative selection	1326409
35231790	35231813	6	+	26627737	RPE1	viability after 15 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-1.5385804517104944	[691]	[73,60]	-7	hSpCas9	negative selection	1326410
35232892	35232915	6	+	26627737	RPE1	viability after 15 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	1.2255621374759036	[341]	[184,265]	7	hSpCas9	negative selection	1326411
35233265	35233288	6	+	26627737	RPE1	viability after 15 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.17293772891822284	[595]	[202,97]	-1	hSpCas9	negative selection	1326412
35237903	35237926	6	+	26627737	RPE1	viability after 15 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	1.3085132721710977	[1098]	[937,607]	7	hSpCas9	negative selection	1326413
35214482	35214505	6	+	26627737	RPE1	viability after 18 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.15799121922604253	[1539]	[483,441]	1	hSpCas9	negative selection	1408723
35228615	35228638	6	+	26627737	RPE1	viability after 18 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.049199707815507865	[1373]	[504,253]	0	hSpCas9	negative selection	1408724
35231790	35231813	6	+	26627737	RPE1	viability after 18 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-1.5197547885418623	[691]	[97,29]	-7	hSpCas9	negative selection	1408725
35232892	35232915	6	+	26627737	RPE1	viability after 18 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	1.922167039854807	[341]	[299,402]	8	hSpCas9	negative selection	1408726
35233265	35233288	6	+	26627737	RPE1	viability after 18 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-1.2604546221188055	[595]	[41,93]	-7	hSpCas9	negative selection	1408727
35237903	35237926	6	+	26627737	RPE1	viability after 18 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	1.2872267923345908	[1098]	[966,463]	7	hSpCas9	negative selection	1408728
35214482	35214505	6	+	26627737	HeLa	viability after 8 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	1.1991792672992327	[359]	[372,334,372]	8	hSpCas9	negative selection	1491038
35228615	35228638	6	+	26627737	HeLa	viability after 8 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.08096598966439195	[875]	[666,306,300]	0	hSpCas9	negative selection	1491039
35231790	35231813	6	+	26627737	HeLa	viability after 8 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	0.22388635804382073	[186]	[191,12,100]	2	hSpCas9	negative selection	1491040
35232892	35232915	6	+	26627737	HeLa	viability after 8 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.2814186261097674	[669]	[275,255,502]	2	hSpCas9	negative selection	1491041
35233265	35233288	6	+	26627737	HeLa	viability after 8 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.5199784607923463	[280]	[46,138,62]	-5	hSpCas9	negative selection	1491042
35237903	35237926	6	+	26627737	HeLa	viability after 8 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.27527512392131215	[683]	[375,405,305]	2	hSpCas9	negative selection	1491043
35214482	35214505	6	+	26627737	HeLa	viability after 12 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.014633930724410937	[359]	[157,188,99]	0	hSpCas9	negative selection	1573353
35228615	35228638	6	+	26627737	HeLa	viability after 12 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	-0.4357562831295301	[875]	[219,319,255]	-4	hSpCas9	negative selection	1573354
35231790	35231813	6	+	26627737	HeLa	viability after 12 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-0.30178247722752594	[186]	[119,31,40]	-3	hSpCas9	negative selection	1573355
35232892	35232915	6	+	26627737	HeLa	viability after 12 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.14473509161050035	[669]	[182,331,396]	1	hSpCas9	negative selection	1573356
35233265	35233288	6	+	26627737	HeLa	viability after 12 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-1.3200318645422353	[280]	[22,63,49]	-8	hSpCas9	negative selection	1573357
35237903	35237926	6	+	26627737	HeLa	viability after 12 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.06273684317102413	[683]	[414,230,249]	0	hSpCas9	negative selection	1573358
35214482	35214505	6	+	26627737	HeLa	viability after 15 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.7678037473925532	[359]	[332,243,163]	6	hSpCas9	negative selection	1655668
35228615	35228638	6	+	26627737	HeLa	viability after 15 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.2036537074249012	[875]	[397,208,642]	1	hSpCas9	negative selection	1655669
35231790	35231813	6	+	26627737	HeLa	viability after 15 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	0.4578437206694881	[186]	[166,63,79]	4	hSpCas9	negative selection	1655670
35232892	35232915	6	+	26627737	HeLa	viability after 15 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	-0.21343197236329958	[669]	[311,214,172]	-2	hSpCas9	negative selection	1655671
35233265	35233288	6	+	26627737	HeLa	viability after 15 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-1.4073895847133118	[280]	[17,64,46]	-8	hSpCas9	negative selection	1655672
35237903	35237926	6	+	26627737	HeLa	viability after 15 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.2565071387054668	[683]	[442,238,312]	2	hSpCas9	negative selection	1655673
35214482	35214505	6	+	26627737	HeLa	viability after 18 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.7430333153838868	[359]	[215,200,163]	6	hSpCas9	negative selection	1737983
35228615	35228638	6	+	26627737	HeLa	viability after 18 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.20961722176595043	[875]	[279,160,642]	1	hSpCas9	negative selection	1737984
35231790	35231813	6	+	26627737	HeLa	viability after 18 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	0.5240662814267196	[186]	[119,54,79]	4	hSpCas9	negative selection	1737985
35232892	35232915	6	+	26627737	HeLa	viability after 18 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	-0.18893088002617942	[669]	[209,186,172]	-2	hSpCas9	negative selection	1737986
35233265	35233288	6	+	26627737	HeLa	viability after 18 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-1.3622657797447173	[280]	[12,55,46]	-8	hSpCas9	negative selection	1737987
35237903	35237926	6	+	26627737	HeLa	viability after 18 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.33513514244914855	[683]	[326,205,312]	3	hSpCas9	negative selection	1737988
35214482	35214505	6	+	26627737	HCT116	viability after 6 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	1.5028738875262944	[618]	[764,5]	7	hSpCas9	negative selection	1820298
35228615	35228638	6	+	26627737	HCT116	viability after 6 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.1227477245057167	[1398]	[524,81]	0	hSpCas9	negative selection	1820299
35231790	35231813	6	+	26627737	HCT116	viability after 6 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-0.6280615826766147	[215]	[59,0]	-4	hSpCas9	negative selection	1820300
35232892	35232915	6	+	26627737	HCT116	viability after 6 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.2312267428697764	[918]	[108,202]	1	hSpCas9	negative selection	1820301
35233265	35233288	6	+	26627737	HCT116	viability after 6 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.26172148890693947	[548]	[58,127]	1	hSpCas9	negative selection	1820302
35237903	35237926	6	+	26627737	HCT116	viability after 6 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.8152055836267503	[1107]	[174,378]	4	hSpCas9	negative selection	1820303
35214482	35214505	6	+	26627737	HCT116	viability after 8 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.15157698112552365	[453]	[282,294,255]	1	hSpCas9	negative selection	1902613
35228615	35228638	6	+	26627737	HCT116	viability after 8 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	1.3408853666894944	[248]	[378,133,527]	9	hSpCas9	negative selection	1902614
35231790	35231813	6	+	26627737	HCT116	viability after 8 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	0.12903064850086454	[146]	[106,64,93]	1	hSpCas9	negative selection	1902615
35232892	35232915	6	+	26627737	HCT116	viability after 8 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.7185807386828956	[262]	[245,184,283]	6	hSpCas9	negative selection	1902616
35233265	35233288	6	+	26627737	HCT116	viability after 8 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.3514604012439625	[205]	[121,161,149]	4	hSpCas9	negative selection	1902617
35237903	35237926	6	+	26627737	HCT116	viability after 8 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.07445956494734585	[642]	[353,400,363]	0	hSpCas9	negative selection	1902618
35214482	35214505	6	+	26627737	HCT116	viability after 9 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	1.783341994304994	[618]	[764,413]	9	hSpCas9	negative selection	1984928
35228615	35228638	6	+	26627737	HCT116	viability after 9 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.1755083080271156	[1398]	[608,273]	1	hSpCas9	negative selection	1984929
35231790	35231813	6	+	26627737	HCT116	viability after 9 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-3.808263202102036	[215]	[2,4]	-9	hSpCas9	negative selection	1984930
35232892	35232915	6	+	26627737	HCT116	viability after 9 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	-1.4159344925208026	[918]	[139,53]	-7	hSpCas9	negative selection	1984931
35233265	35233288	6	+	26627737	HCT116	viability after 9 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.20043078869087796	[548]	[230,118]	1	hSpCas9	negative selection	1984932
35237903	35237926	6	+	26627737	HCT116	viability after 9 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	-0.2837259204069311	[1107]	[380,133]	-2	hSpCas9	negative selection	1984933
35214482	35214505	6	+	26627737	HCT116	viability after 12 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	-0.1296872468874674	[453]	[128,256,276]	-1	hSpCas9	negative selection	2067243
35228615	35228638	6	+	26627737	HCT116	viability after 12 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	1.6193020137394056	[248]	[582,270,332]	9	hSpCas9	negative selection	2067244
35231790	35231813	6	+	26627737	HCT116	viability after 12 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	0.49301998081666065	[146]	[107,98,118]	5	hSpCas9	negative selection	2067245
35232892	35232915	6	+	26627737	HCT116	viability after 12 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.5079191716292999	[262]	[188,184,215]	5	hSpCas9	negative selection	2067246
35233265	35233288	6	+	26627737	HCT116	viability after 12 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.41650130131950686	[205]	[107,198,130]	4	hSpCas9	negative selection	2067247
35237903	35237926	6	+	26627737	HCT116	viability after 12 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	-0.10276501825526474	[642]	[301,431,213]	-1	hSpCas9	negative selection	2067248
35214482	35214505	6	+	26627737	HCT116	viability after 15 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.3065625828810855	[453]	[317,422,226]	3	hSpCas9	negative selection	2149558
35228615	35228638	6	+	26627737	HCT116	viability after 15 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	1.4235350206571713	[248]	[595,395,186]	9	hSpCas9	negative selection	2149559
35231790	35231813	6	+	26627737	HCT116	viability after 15 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	0.18623088387302855	[146]	[80,164,40]	2	hSpCas9	negative selection	2149560
35232892	35232915	6	+	26627737	HCT116	viability after 15 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.6000704222697052	[262]	[218,185,279]	5	hSpCas9	negative selection	2149561
35233265	35233288	6	+	26627737	HCT116	viability after 15 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.09621649652763414	[205]	[74,160,136]	1	hSpCas9	negative selection	2149562
35237903	35237926	6	+	26627737	HCT116	viability after 15 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	-0.15609652778550576	[642]	[493,188,330]	-2	hSpCas9	negative selection	2149563
35214482	35214505	6	+	26627737	HCT116	viability after 18 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	-0.05677227973675203	[453]	[48,277,305]	0	hSpCas9	negative selection	2231873
35228615	35228638	6	+	26627737	HCT116	viability after 18 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	1.6145844080008462	[248]	[544,183,389]	9	hSpCas9	negative selection	2231874
35231790	35231813	6	+	26627737	HCT116	viability after 18 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	0.6861474719534925	[146]	[94,173,67]	5	hSpCas9	negative selection	2231875
35232892	35232915	6	+	26627737	HCT116	viability after 18 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.5934002871305208	[262]	[177,201,194]	5	hSpCas9	negative selection	2231876
35233265	35233288	6	+	26627737	HCT116	viability after 18 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.4662842223013202	[205]	[97,168,143]	4	hSpCas9	negative selection	2231877
35237903	35237926	6	+	26627737	HCT116	viability after 18 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.4290105725282385	[642]	[519,449,276]	3	hSpCas9	negative selection	2231878
35232859	35232882	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATTGCATGAACAAGAACCACGG	SCUBE3	ENSG00000146197	-0.22921144110487424	[4,4]	[3,2]	-3	hSpCas9	positive selection	3019078
35233267	35233290	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.6504094072273923	[2,3]	[2,0]	-7	hSpCas9	positive selection	3019079
35227626	35227649	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	-0.12093480617120948	[3,3]	[3,1]	-2	hSpCas9	positive selection	3019080
35237975	35237998	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCAGCATGAAGCCCACAGGG	SCUBE3	ENSG00000146197	-0.5986183783780673	[2,2]	[2,0]	-7	hSpCas9	positive selection	3019081
35232859	35232882	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATTGCATGAACAAGAACCACGG	SCUBE3	ENSG00000146197	-0.09107009115897183	[4,4]	[4,1]	-1	hSpCas9	positive selection	3086936
35233267	35233290	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.15425540148199254	[2,2]	[3,0]	-2	hSpCas9	positive selection	3086937
35227626	35227649	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	-1.0379915031456115	[3,3]	[1,0]	-9	hSpCas9	positive selection	3086938
35237975	35237998	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCAGCATGAAGCCCACAGGG	SCUBE3	ENSG00000146197	-0.18187244491758858	[2,2]	[2,0]	-3	hSpCas9	positive selection	3086939
35231830	35231853		+	24336571	A375	resistance to PLX after 7 days	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	0.2548951732611059	[7,7]	[8,9]	7	hSpCas9	positive selection	3143010
35231819	35231842		-	24336571	A375	resistance to PLX after 7 days	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	0.013002437505637177	[11,11]	[9,13]	0	hSpCas9	positive selection	3143011
35232918	35232941		+	24336571	A375	resistance to PLX after 7 days	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.20231444335264667	[13,15]	[16,16]	6	hSpCas9	positive selection	3143012
35231830	35231853		+	24336571	A375	resistance to PLX after 14 days	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	0.770664072803682	[10,8]	[7,7]	6	hSpCas9	positive selection	3200803
35231819	35231842		-	24336571	A375	resistance to PLX after 14 days	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.27786988749410135	[10,13]	[3,4]	-3	hSpCas9	positive selection	3200804
35232918	35232941		+	24336571	A375	resistance to PLX after 14 days	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	1.7137495941778997	[9,16]	[25,16]	9	hSpCas9	positive selection	3200805
35231830	35231853		+	24336571	A375	viability after 7 days	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.6204555840560899	[13]	[7,7]	-7	hSpCas9	negative selection	3258596
35231819	35231842		-	24336571	A375	viability after 7 days	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.06694437320806258	[12]	[11,11]	-1	hSpCas9	negative selection	3258597
35232918	35232941		+	24336571	A375	viability after 7 days	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.28977171423768794	[12]	[13,15]	4	hSpCas9	negative selection	3258598
35231830	35231853		+	24336571	A375	viability after 14 days	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.2953381579154989	[13]	[10,8]	-3	hSpCas9	negative selection	3316389
35231819	35231842		-	24336571	A375	viability after 14 days	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	0.005182988355395203	[12]	[10,13]	0	hSpCas9	negative selection	3316390
35232918	35232941		+	24336571	A375	viability after 14 days	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.20399051182614591	[12]	[9,16]	2	hSpCas9	negative selection	3316391
35231819	35231842	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	0.24609895602258092	[257,257]	[1,1]	1	hSpCas9	positive selection	3391514
35237937	35237960	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	1.529405756882636	[52,52]	[0,0]	6	hSpCas9	positive selection	3391515
35231830	35231853	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.47059424311736403	[211,211]	[0,0]	-3	hSpCas9	positive selection	3391516
35232858	35232881	6	+	26780180	HT29	viability (Avana library 4 designs)	AATTGCATGAACAAGAACCACGG	SCUBE3	ENSG00000146197	-0.101429814830083	[]	[]	-2	hSpCas9	negative selection	3457510
35233266	35233289	6	+	26780180	HT29	viability (Avana library 4 designs)	AGTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	1.1687475130475	[]	[]	4	hSpCas9	negative selection	3457511
35227625	35227648	6	+	26780180	HT29	viability (Avana library 4 designs)	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.749167282650445	[]	[]	3	hSpCas9	negative selection	3457512
35237975	35237998	6	-	26780180	HT29	viability (Avana library 4 designs)	GCTGCAGCATGAAGCCCACAGGG	SCUBE3	ENSG00000146197	1.38404237496463	[]	[]	5	hSpCas9	negative selection	3457513
35227625	35227648	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	3.32513107442976	[]	[]	5	hSpCas9	negative selection	3556498
35232858	35232881	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATTGCATGAACAAGAACCACGG	SCUBE3	ENSG00000146197	-4.24445993966739	[]	[]	-5	hSpCas9	negative selection	3556499
35233266	35233289	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	1.76938285431726	[]	[]	2	hSpCas9	negative selection	3556500
35237975	35237998	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCAGCATGAAGCCCACAGGG	SCUBE3	ENSG00000146197	4.43581810307043	[]	[]	7	hSpCas9	negative selection	3556501
35227662	35227685	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGCAAGTCTGGCTACACAGGGG	SCUBE3	ENSG00000146197	-0.0789635773455306	[]	[]	0	hSpCas9	negative selection	3556502
35233281	35233304	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCGATGCATGTCTTCCCGTCGG	SCUBE3	ENSG00000146197	0.27219991063331	[]	[]	0	hSpCas9	negative selection	3556503
35227625	35227648	6	+	26780180	A375	viability (Avana lentiGuide)	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	-4.60636513046532	[]	[]	-7	hSpCas9	negative selection	3665157
35232858	35232881	6	+	26780180	A375	viability (Avana lentiGuide)	AATTGCATGAACAAGAACCACGG	SCUBE3	ENSG00000146197	5.80640776782488	[]	[]	5	hSpCas9	negative selection	3665158
35233266	35233289	6	+	26780180	A375	viability (Avana lentiGuide)	AGTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	0.435222897257654	[]	[]	0	hSpCas9	negative selection	3665159
35237975	35237998	6	-	26780180	A375	viability (Avana lentiGuide)	GCTGCAGCATGAAGCCCACAGGG	SCUBE3	ENSG00000146197	-5.6224157179789	[]	[]	-8	hSpCas9	negative selection	3665160
35227662	35227685	6	+	26780180	A375	viability (Avana lentiGuide)	CTGCAAGTCTGGCTACACAGGGG	SCUBE3	ENSG00000146197	-2.62648298600928	[]	[]	-5	hSpCas9	negative selection	3665161
35233281	35233304	6	-	26780180	A375	viability (Avana lentiGuide)	ACCGATGCATGTCTTCCCGTCGG	SCUBE3	ENSG00000146197	1.65608154037959	[]	[]	2	hSpCas9	negative selection	3665162
35227625	35227648	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	-0.018380277835257336	[4]	[5,2]	0	hSpCas9	positive selection	3773764
35232858	35232881	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATTGCATGAACAAGAACCACGG	SCUBE3	ENSG00000146197	-0.2033524869689976	[6]	[5,5]	-3	hSpCas9	positive selection	3773765
35233266	35233289	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.14518481300822283	[4]	[3,3]	-2	hSpCas9	positive selection	3773766
35237975	35237998	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCAGCATGAAGCCCACAGGG	SCUBE3	ENSG00000146197	0.48342291926234854	[4]	[6,5]	9	hSpCas9	positive selection	3773767
35227662	35227685	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGCAAGTCTGGCTACACAGGGG	SCUBE3	ENSG00000146197	-0.18865801374578992	[4]	[4,2]	-3	hSpCas9	positive selection	3773768
35233281	35233304	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCGATGCATGTCTTCCCGTCGG	SCUBE3	ENSG00000146197	0.06927036952429445	[5]	[5,4]	1	hSpCas9	positive selection	3773769
35227625	35227648	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.23321939868072528	[4]	[4,4]	6	hSpCas9	positive selection	3882371
35232858	35232881	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATTGCATGAACAAGAACCACGG	SCUBE3	ENSG00000146197	-0.6172110032121607	[6]	[3,2]	-7	hSpCas9	positive selection	3882372
35233266	35233289	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.11500439461815534	[5]	[5,2]	-2	hSpCas9	positive selection	3882373
35237975	35237998	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCAGCATGAAGCCCACAGGG	SCUBE3	ENSG00000146197	0.2680975178168891	[4]	[3,4]	7	hSpCas9	positive selection	3882374
35227662	35227685	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGCAAGTCTGGCTACACAGGGG	SCUBE3	ENSG00000146197	-0.1219384885744548	[4]	[2,4]	-2	hSpCas9	positive selection	3882375
35233281	35233304	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCGATGCATGTCTTCCCGTCGG	SCUBE3	ENSG00000146197	-0.24353598487722716	[5]	[4,2]	-3	hSpCas9	positive selection	3882376
35237937	35237960	6	+	26780180	A375	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	1.20223408085034	[]	[]	6	hSpCas9	negative selection	3992409
35231830	35231853	6	+	26780180	A375	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	0.82528800590572	[]	[]	3	hSpCas9	negative selection	3992410
35231819	35231842	6	-	26780180	A375	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	1.4413118892485	[]	[]	8	hSpCas9	negative selection	3992411
35232918	35232941	6	+	26780180	A375	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	1.03690666300979	[]	[]	5	hSpCas9	negative selection	3992412
35237905	35237928	6	-	26780180	A375	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	1.21317404547417	[]	[]	6	hSpCas9	negative selection	3992413
35232959	35232982	6	-	26780180	A375	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.594125742027294	[]	[]	1	hSpCas9	negative selection	3992414
35237937	35237960	6	+	26780180	HT29	viability (GeCKOv2 library)	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	0.983273451495603	[]	[]	4	hSpCas9	negative selection	4100375
35231830	35231853	6	+	26780180	HT29	viability (GeCKOv2 library)	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	0.585248767779474	[]	[]	2	hSpCas9	negative selection	4100376
35231819	35231842	6	-	26780180	HT29	viability (GeCKOv2 library)	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	0.793477031363898	[]	[]	3	hSpCas9	negative selection	4100377
35232918	35232941	6	+	26780180	HT29	viability (GeCKOv2 library)	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	1.0678802346577	[]	[]	5	hSpCas9	negative selection	4100378
35237905	35237928	6	-	26780180	HT29	viability (GeCKOv2 library)	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	1.27029345667831	[]	[]	6	hSpCas9	negative selection	4100379
35232959	35232982	6	-	26780180	HT29	viability (GeCKOv2 library)	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.398474562391392	[]	[]	1	hSpCas9	negative selection	4100380
35231830	35231853	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	0.05367005991725257	[3]	[1,2]	1	hSpCas9	positive selection	4168800
35231819	35231842	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.34565022654884847	[4]	[1,2]	-7	hSpCas9	positive selection	4168801
35232918	35232941	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.3647877243760673	[3]	[2,4]	8	hSpCas9	positive selection	4168802
35231830	35231853	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	0.5977298941374909	[3]	[3,3,4,0]	4	hSpCas9	positive selection	4232822
35231819	35231842	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	1.038316615995212	[4]	[5,2,1,3]	7	hSpCas9	positive selection	4232823
35232918	35232941	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	1.0708837227275545	[3]	[1,5,3,3]	7	hSpCas9	positive selection	4232824
35232918	35232941	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.06442892636017328	[4]	[3,2]	1	hSpCas9	positive selection	4296706
35237905	35237928	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	-0.1635473894377545	[3]	[2,1]	-3	hSpCas9	positive selection	4296707
35232959	35232982	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.3721100453620266	[4]	[3,4]	7	hSpCas9	positive selection	4296708
35231819	35231842	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	0.4105986255514301	[3]	[3,4]	8	hSpCas9	positive selection	4360960
35237937	35237960	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.24546239546151344	[2]	[1,0]	-5	hSpCas9	positive selection	4360961
35231830	35231853	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	0.3060684942295666	[3]	[3,3]	6	hSpCas9	positive selection	4360962
35227640	35227662	6	-	27760321	OCIAML3	viability	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	0.3450787529248355	[899,786]	[648,1079]	4	hSpCas9	negative selection	4437358
35233188	35233210	6	+	27760321	OCIAML3	viability	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	-0.16323452017209417	[638,474]	[349,431]	-2	hSpCas9	negative selection	4437359
35233267	35233289	6	+	27760321	OCIAML3	viability	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.09216963317280139	[512,463]	[259,485]	-1	hSpCas9	negative selection	4437360
35239760	35239782	6	+	27760321	OCIAML3	viability	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	-0.0660054800651752	[382,326]	[200,346]	0	hSpCas9	negative selection	4437361
35240389	35240411	6	-	27760321	OCIAML3	viability	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	0.18642337783349416	[440,375]	[321,414]	2	hSpCas9	negative selection	4437362
35227640	35227662	6	-	27760321	OCIAML2	viability	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	-0.4498317563669757	[899,786]	[450,560]	-5	hSpCas9	negative selection	4520821
35233188	35233210	6	+	27760321	OCIAML2	viability	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	0.17592079103030028	[638,474]	[507,499]	2	hSpCas9	negative selection	4520822
35233267	35233289	6	+	27760321	OCIAML2	viability	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.41362301928607936	[512,463]	[254,350]	-5	hSpCas9	negative selection	4520823
35239760	35239782	6	+	27760321	OCIAML2	viability	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	-0.21594869750867945	[382,326]	[198,308]	-3	hSpCas9	negative selection	4520824
35240389	35240411	6	-	27760321	OCIAML2	viability	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	-0.17134287267770174	[440,375]	[260,333]	-2	hSpCas9	negative selection	4520825
35227640	35227662	6	-	27760321	MV411	viability	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	0.7889273832768634	[899,786]	[963,952]	6	hSpCas9	negative selection	4604284
35233188	35233210	6	+	27760321	MV411	viability	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	-0.5534305920049527	[638,474]	[71,512]	-4	hSpCas9	negative selection	4604285
35233267	35233289	6	+	27760321	MV411	viability	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	0.1150292169920428	[512,463]	[379,301]	0	hSpCas9	negative selection	4604286
35239760	35239782	6	+	27760321	MV411	viability	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	0.8440022960059133	[382,326]	[381,474]	6	hSpCas9	negative selection	4604287
35240389	35240411	6	-	27760321	MV411	viability	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	1.6962810940634507	[440,375]	[1283,249]	9	hSpCas9	negative selection	4604288
35227640	35227662	6	-	27760321	HL60	viability	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	0.0013254223101104579	[899,786]	[493,893]	0	hSpCas9	negative selection	4687747
35233188	35233210	6	+	27760321	HL60	viability	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	-0.5168064896640022	[638,474]	[288,342]	-5	hSpCas9	negative selection	4687748
35233267	35233289	6	+	27760321	HL60	viability	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	0.19794208568799196	[512,463]	[385,532]	2	hSpCas9	negative selection	4687749
35239760	35239782	6	+	27760321	HL60	viability	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	0.9955065327036279	[382,326]	[603,546]	9	hSpCas9	negative selection	4687750
35240389	35240411	6	-	27760321	HL60	viability	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	0.25956933728122833	[440,375]	[403,391]	3	hSpCas9	negative selection	4687751
35227640	35227662	6	-	27760321	HT1080	viability	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	0.7375707800719902	[786,613]	[270,677]	4	hSpCas9	negative selection	4771210
35233188	35233210	6	+	27760321	HT1080	viability	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	-0.4283281726191932	[474,370]	[108,142]	-2	hSpCas9	negative selection	4771211
35233267	35233289	6	+	27760321	HT1080	viability	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.9840227090698417	[463,361]	[107,55]	-4	hSpCas9	negative selection	4771212
35239760	35239782	6	+	27760321	HT1080	viability	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	0.35440383849759477	[326,254]	[183,108]	1	hSpCas9	negative selection	4771213
35240389	35240411	6	-	27760321	HT1080	viability	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	-0.2863826776333255	[375,293]	[65,156]	-1	hSpCas9	negative selection	4771214
35227640	35227662	6	-	27760321	HT29	viability after 7 days	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	-0.011347594154790142	[786,613]	[877,740,1052]	0	hSpCas9	negative selection	4854673
35233188	35233210	6	+	27760321	HT29	viability after 7 days	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	0.2647744673577366	[474,370]	[587,674,685]	4	hSpCas9	negative selection	4854674
35233267	35233289	6	+	27760321	HT29	viability after 7 days	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.07390507474246419	[463,361]	[653,597,288]	-1	hSpCas9	negative selection	4854675
35239760	35239782	6	+	27760321	HT29	viability after 7 days	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	0.4205460588238136	[326,254]	[538,309,652]	6	hSpCas9	negative selection	4854676
35240389	35240411	6	-	27760321	HT29	viability after 7 days	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	-0.1326645594405692	[375,293]	[536,340,322]	-2	hSpCas9	negative selection	4854677
35227640	35227662	6	-	27760321	HT29	viability after 25 days	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	0.2252136780879983	[786,613]	[824,809,1205]	2	hSpCas9	negative selection	4938136
35233188	35233210	6	+	27760321	HT29	viability after 25 days	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	0.5079296853197504	[474,370]	[372,857,868]	5	hSpCas9	negative selection	4938137
35233267	35233289	6	+	27760321	HT29	viability after 25 days	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	0.013104551624015914	[463,361]	[385,612,429]	0	hSpCas9	negative selection	4938138
35239760	35239782	6	+	27760321	HT29	viability after 25 days	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	0.5076198803309899	[326,254]	[544,326,548]	5	hSpCas9	negative selection	4938139
35240389	35240411	6	-	27760321	HT29	viability after 25 days	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	0.6402437378216937	[375,293]	[447,708,646]	7	hSpCas9	negative selection	4938140
35227640	35227662	6	-	27760321	HT29	viability after 22 days	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	0.2791936246694158	[786,613]	[1124,753,1065]	3	hSpCas9	negative selection	5021599
35233188	35233210	6	+	27760321	HT29	viability after 22 days	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	0.40389913876208117	[474,370]	[676,641,620]	4	hSpCas9	negative selection	5021600
35233267	35233289	6	+	27760321	HT29	viability after 22 days	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.14919002401449988	[463,361]	[677,373,230]	-1	hSpCas9	negative selection	5021601
35239760	35239782	6	+	27760321	HT29	viability after 22 days	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	-0.0944715244749606	[326,254]	[272,288,384]	-1	hSpCas9	negative selection	5021602
35240389	35240411	6	-	27760321	HT29	viability after 22 days	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	0.3639109031393199	[375,293]	[263,598,639]	4	hSpCas9	negative selection	5021603
35227640	35227662	6	-	27760321	HT29	viability after 19 days	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	-0.18387571899928679	[786,613]	[862,648,622]	-2	hSpCas9	negative selection	5105062
35233188	35233210	6	+	27760321	HT29	viability after 19 days	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	0.39517826377717	[474,370]	[705,449,754]	4	hSpCas9	negative selection	5105063
35233267	35233289	6	+	27760321	HT29	viability after 19 days	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	0.4910751862536125	[463,361]	[578,384,1004]	5	hSpCas9	negative selection	5105064
35239760	35239782	6	+	27760321	HT29	viability after 19 days	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	0.020330748264685006	[326,254]	[476,160,386]	0	hSpCas9	negative selection	5105065
35240389	35240411	6	-	27760321	HT29	viability after 19 days	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	0.1945340907846802	[375,293]	[448,501,367]	1	hSpCas9	negative selection	5105066
35227640	35227662	6	-	27760321	HT29	viability after 16 days	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	0.13641590184229435	[786,613]	[870,594,1125]	1	hSpCas9	negative selection	5188525
35233188	35233210	6	+	27760321	HT29	viability after 16 days	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	0.6233497034235558	[474,370]	[684,724,772]	7	hSpCas9	negative selection	5188526
35233267	35233289	6	+	27760321	HT29	viability after 16 days	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	0.12663607623372514	[463,361]	[278,885,316]	1	hSpCas9	negative selection	5188527
35239760	35239782	6	+	27760321	HT29	viability after 16 days	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	0.7072334189093328	[326,254]	[692,176,748]	8	hSpCas9	negative selection	5188528
35240389	35240411	6	-	27760321	HT29	viability after 16 days	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	0.7667023215488783	[375,293]	[739,476,709]	8	hSpCas9	negative selection	5188529
35227640	35227662	6	-	27760321	HT29	viability after 13 days	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	0.2025580555715143	[786,613]	[1213,662,927]	2	hSpCas9	negative selection	5271988
35233188	35233210	6	+	27760321	HT29	viability after 13 days	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	0.41944181127511726	[474,370]	[505,751,707]	5	hSpCas9	negative selection	5271989
35233267	35233289	6	+	27760321	HT29	viability after 13 days	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.23576896558692378	[463,361]	[373,445,400]	-3	hSpCas9	negative selection	5271990
35239760	35239782	6	+	27760321	HT29	viability after 13 days	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	0.016969856079804224	[326,254]	[313,288,416]	0	hSpCas9	negative selection	5271991
35240389	35240411	6	-	27760321	HT29	viability after 13 days	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	0.31938075712627634	[375,293]	[352,681,423]	4	hSpCas9	negative selection	5271992
35227640	35227662	6	-	27760321	HT29	viability after 10 days	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	-0.20948874244678206	[786,613]	[732,685,845]	-3	hSpCas9	negative selection	5355451
35233188	35233210	6	+	27760321	HT29	viability after 10 days	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	0.3250111502846347	[474,370]	[698,609,673]	4	hSpCas9	negative selection	5355452
35233267	35233289	6	+	27760321	HT29	viability after 10 days	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.07291779881269073	[463,361]	[492,496,480]	-1	hSpCas9	negative selection	5355453
35239760	35239782	6	+	27760321	HT29	viability after 10 days	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	0.06094849465817603	[326,254]	[322,405,407]	0	hSpCas9	negative selection	5355454
35240389	35240411	6	-	27760321	HT29	viability after 10 days	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	0.15434178896715123	[375,293]	[490,522,385]	2	hSpCas9	negative selection	5355455
35227640	35227662	6	-	27760321	MOLM13	viability	ATGCACTTGTATGACCTCGGGG	SCUBE3	ENSG00000146197	-0.29721091251412346	[899,786]	[319,442]	-2	hSpCas9	negative selection	5438914
35233188	35233210	6	+	27760321	MOLM13	viability	CATGCAACTATGGTAACGGCGG	SCUBE3	ENSG00000146197	-0.7078023070657771	[638,474]	[86,278]	-4	hSpCas9	negative selection	5438915
35233267	35233289	6	+	27760321	MOLM13	viability	GTTTGTGCTCCATACCGACGGG	SCUBE3	ENSG00000146197	-0.639637042334214	[512,463]	[179,173]	-4	hSpCas9	negative selection	5438916
35239760	35239782	6	+	27760321	MOLM13	viability	GAGTGCCGCTTAAACAACGGGG	SCUBE3	ENSG00000146197	0.2926453560214949	[382,326]	[216,267]	2	hSpCas9	negative selection	5438917
35240389	35240411	6	-	27760321	MOLM13	viability	TGGTCACAGGTTCGATCAAAGG	SCUBE3	ENSG00000146197	-0.20101025515350493	[440,375]	[174,220]	-1	hSpCas9	negative selection	5438918
35232918	35232941	6	+	27260156	BXPC3	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.007088516625509689	[1001]	[1062,952,1076,1124]	0	hSpCas9	negative selection	5569166
35237905	35237928	6	-	27260156	BXPC3	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.30671814243648826	[569]	[632,734,760,838]	6	hSpCas9	negative selection	5569167
35232959	35232982	6	-	27260156	BXPC3	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.08733424710952087	[1255]	[1048,1209,1357,1357]	-2	hSpCas9	negative selection	5569168
35231819	35231842	6	-	27260156	BXPC3	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.1116938673362684	[766]	[778,568,711,932]	-3	hSpCas9	negative selection	5633420
35237937	35237960	6	+	27260156	BXPC3	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.3084447617148647	[217]	[130,185,245,177]	-6	hSpCas9	negative selection	5633421
35231830	35231853	6	+	27260156	BXPC3	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.0423327593375481	[943]	[832,902,1001,1127]	-1	hSpCas9	negative selection	5633422
35232918	35232941	6	+	27260156	A673	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.18048617772599562	[1001]	[1427,1340,1202,1495]	4	hSpCas9	negative selection	5690417
35237905	35237928	6	-	27260156	A673	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.2879031681718654	[569]	[911,708,898,831]	6	hSpCas9	negative selection	5690418
35232959	35232982	6	-	27260156	A673	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.0288900220740147	[1255]	[1667,1535,1415,1300]	0	hSpCas9	negative selection	5690419
35231819	35231842	6	-	27260156	A673	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.2575496645475306	[766]	[935,603,723,843]	-6	hSpCas9	negative selection	5754671
35237937	35237960	6	+	27260156	A673	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.481708062430539	[217]	[236,172,169,174]	-8	hSpCas9	negative selection	5754672
35231830	35231853	6	+	27260156	A673	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.14263502752698076	[943]	[1142,1073,854,1047]	-4	hSpCas9	negative selection	5754673
35232918	35232941	6	+	27260156	A375	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.2030764747558964	[1001]	[1409,1627,1156,1240]	3	hSpCas9	negative selection	5811668
35237905	35237928	6	-	27260156	A375	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.3789343950923027	[569]	[1091,1070,795,566]	5	hSpCas9	negative selection	5811669
35232959	35232982	6	-	27260156	A375	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.13803328647097057	[1255]	[1647,1613,1675,1523]	2	hSpCas9	negative selection	5811670
35231819	35231842	6	-	27260156	A375	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.06494396477633524	[766]	[909,992,795,754]	-1	hSpCas9	negative selection	5875922
35237937	35237960	6	+	27260156	A375	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.038304103402994505	[217]	[195,292,363,154]	0	hSpCas9	negative selection	5875923
35231830	35231853	6	+	27260156	A375	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.052723143512023785	[943]	[1337,1088,1081,778]	0	hSpCas9	negative selection	5875924
35232918	35232941	6	+	27260156	COLO741	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.19204496985648367	[1001]	[1674,1543,1202]	4	hSpCas9	negative selection	5932919
35237905	35237928	6	-	27260156	COLO741	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	-0.037239118427074114	[569]	[816,616,702]	-1	hSpCas9	negative selection	5932920
35232959	35232982	6	-	27260156	COLO741	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.05974649529948284	[1255]	[1831,1437,1381]	-1	hSpCas9	negative selection	5932921
35231819	35231842	6	-	27260156	COLO741	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.19986329265363623	[766]	[876,930,758]	-4	hSpCas9	negative selection	5997173
35237937	35237960	6	+	27260156	COLO741	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.33991599589934895	[217]	[276,244,147]	-6	hSpCas9	negative selection	5997174
35231830	35231853	6	+	27260156	COLO741	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.18799981227570772	[943]	[1364,1007,842]	-4	hSpCas9	negative selection	5997175
35232918	35232941	6	+	27260156	CAL120	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.0747469997110326	[1001]	[1347,1269,1325]	1	hSpCas9	negative selection	6054170
35237905	35237928	6	-	27260156	CAL120	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.38731996327206414	[569]	[921,1045,815]	6	hSpCas9	negative selection	6054171
35232959	35232982	6	-	27260156	CAL120	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.4335194126029186	[1255]	[1201,1167,1108]	-6	hSpCas9	negative selection	6054172
35231819	35231842	6	-	27260156	CAL120	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.3806424423933249	[766]	[939,716,575]	-5	hSpCas9	negative selection	6118424
35237937	35237960	6	+	27260156	CAL120	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	0.26141539122353485	[217]	[244,487,231]	4	hSpCas9	negative selection	6118425
35231830	35231853	6	+	27260156	CAL120	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.06580356359914952	[943]	[1683,1090,683]	-1	hSpCas9	negative selection	6118426
35232918	35232941	6	+	27260156	CADOES1	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	-0.12222341417829574	[1001]	[877,1086,816,634]	-2	hSpCas9	negative selection	6175421
35237905	35237928	6	-	27260156	CADOES1	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.3527827493748162	[569]	[677,719,761,542]	6	hSpCas9	negative selection	6175422
35232959	35232982	6	-	27260156	CADOES1	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.20087094823073715	[1255]	[904,949,872,1349]	-3	hSpCas9	negative selection	6175423
35231819	35231842	6	-	27260156	CADOES1	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.3916631255040594	[766]	[429,450,802,488]	-6	hSpCas9	negative selection	6239675
35237937	35237960	6	+	27260156	CADOES1	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.0526095767850987	[217]	[106,132,168,379]	-1	hSpCas9	negative selection	6239676
35231830	35231853	6	+	27260156	CADOES1	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.193186767038798	[943]	[591,781,756,947]	-3	hSpCas9	negative selection	6239677
35232918	35232941	6	+	27260156	EWS502	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.0725775758115581	[1001]	[1193,1045,1096,1115]	1	hSpCas9	negative selection	6296672
35237905	35237928	6	-	27260156	EWS502	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.13478319612929435	[569]	[541,680,655,792]	2	hSpCas9	negative selection	6296673
35232959	35232982	6	-	27260156	EWS502	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.05652537908631183	[1255]	[1118,1358,1393,1255]	-1	hSpCas9	negative selection	6296674
35231819	35231842	6	-	27260156	EWS502	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.2466332545387075	[766]	[473,576,763,972]	-4	hSpCas9	negative selection	6360926
35237937	35237960	6	+	27260156	EWS502	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.4407299878079347	[217]	[146,179,143,213]	-6	hSpCas9	negative selection	6360927
35231830	35231853	6	+	27260156	EWS502	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.2908444942309847	[943]	[648,845,822,978]	-5	hSpCas9	negative selection	6360928
35232918	35232941	6	+	27260156	EW8	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.14405351576960124	[1001]	[808,1154,804,824]	2	hSpCas9	negative selection	6417923
35237905	35237928	6	-	27260156	EW8	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.20723512770055708	[569]	[463,596,528,534]	4	hSpCas9	negative selection	6417924
35232959	35232982	6	-	27260156	EW8	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.044151488745711065	[1255]	[1154,1094,918,1059]	0	hSpCas9	negative selection	6417925
35231819	35231842	6	-	27260156	EW8	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	0.003443973524051458	[766]	[612,426,453,1021]	0	hSpCas9	negative selection	6482177
35237937	35237960	6	+	27260156	EW8	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	0.05649287024706906	[217]	[273,138,148,187]	1	hSpCas9	negative selection	6482178
35231830	35231853	6	+	27260156	EW8	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.2668744143504026	[943]	[686,542,662,648]	-5	hSpCas9	negative selection	6482179
35232918	35232941	6	+	27260156	CORL105	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.19896848519988364	[1001]	[1601,1142,1299,1345]	4	hSpCas9	negative selection	6539174
35237905	35237928	6	-	27260156	CORL105	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.4079109040897297	[569]	[851,993,1034,680]	7	hSpCas9	negative selection	6539175
35232959	35232982	6	-	27260156	CORL105	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.2589690597742509	[1255]	[1081,1155,1627,1107]	-5	hSpCas9	negative selection	6539176
35231819	35231842	6	-	27260156	CORL105	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.48326156079185745	[766]	[687,496,772,635]	-7	hSpCas9	negative selection	6603428
35237937	35237960	6	+	27260156	CORL105	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.5671214710557131	[217]	[180,175,101,218]	-7	hSpCas9	negative selection	6603429
35231830	35231853	6	+	27260156	CORL105	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.013643535917074567	[943]	[1182,1185,1072,934]	0	hSpCas9	negative selection	6603430
35232918	35232941	6	+	27260156	HS294T	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.0037693172686021903	[1001]	[326,369,478,381]	0	hSpCas9	negative selection	6660425
35237905	35237928	6	-	27260156	HS294T	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.3885235448556234	[569]	[311,302,287,238]	5	hSpCas9	negative selection	6660426
35232959	35232982	6	-	27260156	HS294T	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.2222448178111036	[1255]	[642,438,512,685]	3	hSpCas9	negative selection	6660427
35231819	35231842	6	-	27260156	HS294T	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.2974249819705644	[766]	[177,218,314,262]	-4	hSpCas9	negative selection	6724679
35237937	35237960	6	+	27260156	HS294T	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.9077279669220633	[217]	[29,40,50,61]	-8	hSpCas9	negative selection	6724680
35231830	35231853	6	+	27260156	HS294T	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.22012042638923313	[943]	[182,351,383,350]	-3	hSpCas9	negative selection	6724681
35232918	35232941	6	+	27260156	HCC44	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.2885730385588354	[1001]	[1553,1233,1453,1333]	5	hSpCas9	negative selection	6781676
35237905	35237928	6	-	27260156	HCC44	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	-0.024244171789523816	[569]	[635,494,896,569]	0	hSpCas9	negative selection	6781677
35232959	35232982	6	-	27260156	HCC44	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.3842922904616455	[1255]	[1259,759,1157,1235]	-5	hSpCas9	negative selection	6781678
35231819	35231842	6	-	27260156	HCC44	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.18537270768886427	[766]	[399,983,1042,606]	-3	hSpCas9	negative selection	6845930
35237937	35237960	6	+	27260156	HCC44	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.5821638444613959	[217]	[202,224,95,117]	-7	hSpCas9	negative selection	6845931
35231830	35231853	6	+	27260156	HCC44	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.2852840100637828	[943]	[853,685,1162,868]	-4	hSpCas9	negative selection	6845932
35232918	35232941	6	+	27260156	G402	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.0666903933665377	[1001]	[1172,2305,887,816]	0	hSpCas9	negative selection	6902927
35237905	35237928	6	-	27260156	G402	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.17607909906432012	[569]	[708,969,552,901]	2	hSpCas9	negative selection	6902928
35232959	35232982	6	-	27260156	G402	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.09737349081284408	[1255]	[2080,1485,1298,1735]	1	hSpCas9	negative selection	6902929
35231819	35231842	6	-	27260156	G402	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.22497930534698563	[766]	[1432,832,626,418]	-3	hSpCas9	negative selection	6967181
35237937	35237960	6	+	27260156	G402	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.12669878057150075	[217]	[351,193,209,230]	-1	hSpCas9	negative selection	6967182
35231830	35231853	6	+	27260156	G402	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.8295679305181982	[943]	[566,811,689,524]	-7	hSpCas9	negative selection	6967183
35232918	35232941	6	+	27260156	L33	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.21284554780790854	[1001]	[1133,480,754,1136]	4	hSpCas9	negative selection	7024178
35237905	35237928	6	-	27260156	L33	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.12016668770410316	[569]	[692,271,352,557]	2	hSpCas9	negative selection	7024179
35232959	35232982	6	-	27260156	L33	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.09767216417112046	[1255]	[1314,535,783,1503]	2	hSpCas9	negative selection	7024180
35231819	35231842	6	-	27260156	L33	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.23695650527393425	[766]	[574,244,433,740]	-5	hSpCas9	negative selection	7088432
35237937	35237960	6	+	27260156	L33	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.5001142350774122	[217]	[241,78,44,107]	-8	hSpCas9	negative selection	7088433
35231830	35231853	6	+	27260156	L33	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.36118032723838156	[943]	[782,295,393,804]	-7	hSpCas9	negative selection	7088434
35232918	35232941	6	+	27260156	K562	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	-0.13888108386710396	[1001]	[595,1151,891,610]	-2	hSpCas9	negative selection	7145429
35237905	35237928	6	-	27260156	K562	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	-0.12295614002018773	[569]	[681,400,336,451]	-1	hSpCas9	negative selection	7145430
35232959	35232982	6	-	27260156	K562	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.15231242182600258	[1255]	[1396,937,1299,1303]	1	hSpCas9	negative selection	7145431
35231819	35231842	6	-	27260156	K562	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.6160803824571085	[766]	[406,601,517,272]	-6	hSpCas9	negative selection	7209683
35237937	35237960	6	+	27260156	K562	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.39324903075800344	[217]	[155,133,173,126]	-5	hSpCas9	negative selection	7209684
35231830	35231853	6	+	27260156	K562	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-1.0370836942541253	[943]	[472,673,288,234]	-8	hSpCas9	negative selection	7209685
35232918	35232941	6	+	27260156	HT29	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	-0.03797907316025895	[1001]	[1253,1236,1082,1173]	-1	hSpCas9	negative selection	7266680
35237905	35237928	6	-	27260156	HT29	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.2578426373887221	[569]	[925,886,728,783]	5	hSpCas9	negative selection	7266681
35232959	35232982	6	-	27260156	HT29	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.019409404152488152	[1255]	[1479,1785,1721,1243]	0	hSpCas9	negative selection	7266682
35231819	35231842	6	-	27260156	HT29	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.3400626463477707	[766]	[840,750,852,530]	-6	hSpCas9	negative selection	7330934
35237937	35237960	6	+	27260156	HT29	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	0.023643508432565907	[217]	[261,329,243,246]	0	hSpCas9	negative selection	7330935
35231830	35231853	6	+	27260156	HT29	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.1799170516432529	[943]	[1065,912,1190,885]	-4	hSpCas9	negative selection	7330936
35232918	35232941	6	+	27260156	MHHES1	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.15183499704392878	[1001]	[1426,1376,1266,1006]	2	hSpCas9	negative selection	7387931
35237905	35237928	6	-	27260156	MHHES1	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.47450556751587775	[569]	[895,1170,695,826]	8	hSpCas9	negative selection	7387932
35232959	35232982	6	-	27260156	MHHES1	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.009475651069361657	[1255]	[1581,1550,1521,1053]	0	hSpCas9	negative selection	7387933
35231819	35231842	6	-	27260156	MHHES1	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.1236844405793287	[766]	[928,737,858,667]	-2	hSpCas9	negative selection	7452185
35237937	35237960	6	+	27260156	MHHES1	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.7360975351792425	[217]	[204,105,100,170]	-8	hSpCas9	negative selection	7452186
35231830	35231853	6	+	27260156	MHHES1	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.07678207533961567	[943]	[1250,979,1280,617]	-1	hSpCas9	negative selection	7452187
35232918	35232941	6	+	27260156	MEWO	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.11120222497879251	[1001]	[1213,898,963]	2	hSpCas9	negative selection	7509182
35237905	35237928	6	-	27260156	MEWO	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.31785798489287037	[569]	[715,647,639]	6	hSpCas9	negative selection	7509183
35232959	35232982	6	-	27260156	MEWO	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.0354835724079281	[1255]	[1334,1107,1032]	0	hSpCas9	negative selection	7509184
35231819	35231842	6	-	27260156	MEWO	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.05349530657053858	[766]	[901,691,520]	-1	hSpCas9	negative selection	7573436
35237937	35237960	6	+	27260156	MEWO	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.3674449956510353	[217]	[151,171,148]	-7	hSpCas9	negative selection	7573437
35231830	35231853	6	+	27260156	MEWO	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.02745879746023494	[943]	[1112,685,848]	0	hSpCas9	negative selection	7573438
35232918	35232941	6	+	27260156	LNCAPCLONEFGC	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.12922853508701082	[1001]	[870,923,1220,994]	2	hSpCas9	negative selection	7630433
35237905	35237928	6	-	27260156	LNCAPCLONEFGC	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.15908392081050954	[569]	[508,570,748,503]	2	hSpCas9	negative selection	7630434
35232959	35232982	6	-	27260156	LNCAPCLONEFGC	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.02004160204316996	[1255]	[1352,921,1083,1255]	0	hSpCas9	negative selection	7630435
35231819	35231842	6	-	27260156	LNCAPCLONEFGC	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.15363360618614752	[766]	[415,668,825,617]	-2	hSpCas9	negative selection	7694687
35237937	35237960	6	+	27260156	LNCAPCLONEFGC	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.08305697737458861	[217]	[187,204,163,183]	-1	hSpCas9	negative selection	7694688
35231830	35231853	6	+	27260156	LNCAPCLONEFGC	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.25679127511419264	[943]	[606,677,931,681]	-4	hSpCas9	negative selection	7694689
35232918	35232941	6	+	27260156	PANC0327	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.037587534058010075	[1001]	[877,563,1349,904]	0	hSpCas9	negative selection	7751684
35237905	35237928	6	-	27260156	PANC0327	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.43700080677375824	[569]	[658,354,1149,618]	6	hSpCas9	negative selection	7751685
35232959	35232982	6	-	27260156	PANC0327	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.36428976955329073	[1255]	[800,814,897,953]	-5	hSpCas9	negative selection	7751686
35231819	35231842	6	-	27260156	PANC0327	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.3449962945751154	[766]	[638,651,469,377]	-5	hSpCas9	negative selection	7815938
35237937	35237960	6	+	27260156	PANC0327	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	0.015914102480576897	[217]	[196,165,169,253]	0	hSpCas9	negative selection	7815939
35231830	35231853	6	+	27260156	PANC0327	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.5093614981185831	[943]	[679,508,552,631]	-6	hSpCas9	negative selection	7815940
35232918	35232941	6	+	27260156	NCIH2009	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.2872742159807138	[1001]	[1943,1701,1522]	4	hSpCas9	negative selection	7872935
35237905	35237928	6	-	27260156	NCIH2009	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.8006592208733208	[569]	[1774,1272,1189]	9	hSpCas9	negative selection	7872936
35232959	35232982	6	-	27260156	NCIH2009	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.19398178004773925	[1255]	[1618,1497,1499]	-3	hSpCas9	negative selection	7872937
35231819	35231842	6	-	27260156	NCIH2009	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.19000907132490574	[766]	[1129,1006,715]	-3	hSpCas9	negative selection	7937189
35237937	35237960	6	+	27260156	NCIH2009	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.07937459904283961	[217]	[200,292,352]	-1	hSpCas9	negative selection	7937190
35231830	35231853	6	+	27260156	NCIH2009	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.17887772512795352	[943]	[1687,1149,758]	-2	hSpCas9	negative selection	7937191
35232918	35232941	6	+	27260156	NCIH1373	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	-0.6802136179521939	[1001]	[962,516,484,239]	-6	hSpCas9	negative selection	7994186
35237905	35237928	6	-	27260156	NCIH1373	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.2763069965734802	[569]	[1050,668,609,215]	2	hSpCas9	negative selection	7994187
35232959	35232982	6	-	27260156	NCIH1373	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.45518468273778423	[1255]	[1144,865,838,343]	-4	hSpCas9	negative selection	7994188
35231819	35231842	6	-	27260156	NCIH1373	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-1.1708783876985451	[766]	[249,407,233,164]	-8	hSpCas9	negative selection	8058440
35237937	35237960	6	+	27260156	NCIH1373	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	0.13321823357789742	[217]	[530,165,290,32]	1	hSpCas9	negative selection	8058441
35231830	35231853	6	+	27260156	NCIH1373	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-1.428657382647894	[943]	[321,244,390,165]	-8	hSpCas9	negative selection	8058442
35232918	35232941	6	+	27260156	PATU8902	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	-0.14788205317923464	[1001]	[1390,939,920,1942]	-1	hSpCas9	negative selection	8115437
35237905	35237928	6	-	27260156	PATU8902	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.1360465877606427	[569]	[771,794,727,1273]	1	hSpCas9	negative selection	8115438
35232959	35232982	6	-	27260156	PATU8902	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.01740195692462221	[1255]	[2653,1488,946,2035]	0	hSpCas9	negative selection	8115439
35231819	35231842	6	-	27260156	PATU8902	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.35475246321685205	[766]	[811,914,604,1093]	-4	hSpCas9	negative selection	8179691
35237937	35237960	6	+	27260156	PATU8902	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	0.3181161080051955	[217]	[473,188,494,312]	3	hSpCas9	negative selection	8179692
35231830	35231853	6	+	27260156	PATU8902	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.48834832237361037	[943]	[1237,729,1013,706]	-5	hSpCas9	negative selection	8179693
35232918	35232941	6	+	27260156	PANC1	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.30137220404639	[1001]	[1078,1195,1036,956]	5	hSpCas9	negative selection	8236688
35237905	35237928	6	-	27260156	PANC1	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.09283326300029437	[569]	[377,778,481,499]	1	hSpCas9	negative selection	8236689
35232959	35232982	6	-	27260156	PANC1	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.06924738280069831	[1255]	[1336,1536,785,953]	1	hSpCas9	negative selection	8236690
35231819	35231842	6	-	27260156	PANC1	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	0.05100377947447998	[766]	[706,864,757,462]	0	hSpCas9	negative selection	8300942
35237937	35237960	6	+	27260156	PANC1	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.03491651173891963	[217]	[172,235,134,192]	0	hSpCas9	negative selection	8300943
35231830	35231853	6	+	27260156	PANC1	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.47729408441872423	[943]	[608,700,591,461]	-6	hSpCas9	negative selection	8300944
35232918	35232941	6	+	27260156	PANC0813	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.2264866208876637	[1001]	[1471,1198,1273,1558]	3	hSpCas9	negative selection	8357939
35237905	35237928	6	-	27260156	PANC0813	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.23786449406779636	[569]	[725,914,674,831]	4	hSpCas9	negative selection	8357940
35232959	35232982	6	-	27260156	PANC0813	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.06000625555089645	[1255]	[1665,1569,1908,1045]	1	hSpCas9	negative selection	8357941
35231819	35231842	6	-	27260156	PANC0813	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.25672255144382694	[766]	[835,949,631,611]	-4	hSpCas9	negative selection	8422193
35237937	35237960	6	+	27260156	PANC0813	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.1378875324584552	[217]	[227,210,202,284]	-2	hSpCas9	negative selection	8422194
35231830	35231853	6	+	27260156	PANC0813	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.23375403074839352	[943]	[1008,837,955,971]	-4	hSpCas9	negative selection	8422195
35232918	35232941	6	+	27260156	RDES	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.0778244727340971	[1001]	[989,1050,1393,1509]	1	hSpCas9	negative selection	8479190
35237905	35237928	6	-	27260156	RDES	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.06118377630473454	[569]	[592,689,731,725]	1	hSpCas9	negative selection	8479191
35232959	35232982	6	-	27260156	RDES	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.2501389630210029	[1255]	[912,1184,1501,1316]	-4	hSpCas9	negative selection	8479192
35231819	35231842	6	-	27260156	RDES	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.12448443084754035	[766]	[662,830,736,1042]	-2	hSpCas9	negative selection	8543444
35237937	35237960	6	+	27260156	RDES	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	0.3173164387436078	[217]	[169,272,315,554]	5	hSpCas9	negative selection	8543445
35231830	35231853	6	+	27260156	RDES	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.22723216910683874	[943]	[686,1017,1037,996]	-4	hSpCas9	negative selection	8543446
35232918	35232941	6	+	27260156	PC3	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.0538097052225206	[1001]	[582,1242,1433,1138]	1	hSpCas9	negative selection	8600441
35237905	35237928	6	-	27260156	PC3	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.049663670201537946	[569]	[295,532,1108,706]	1	hSpCas9	negative selection	8600442
35232959	35232982	6	-	27260156	PC3	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.15949855640816035	[1255]	[677,980,2147,1176]	-4	hSpCas9	negative selection	8600443
35231819	35231842	6	-	27260156	PC3	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.1909141521413208	[766]	[435,749,1095,588]	-4	hSpCas9	negative selection	8664695
35237937	35237960	6	+	27260156	PC3	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.9089252445343021	[217]	[51,98,244,138]	-9	hSpCas9	negative selection	8664696
35231830	35231853	6	+	27260156	PC3	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.4330039549895309	[943]	[538,655,1034,677]	-7	hSpCas9	negative selection	8664697
35232918	35232941	6	+	27260156	PATU8988T	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.11868337185400035	[1001]	[907,1070,1007,1234]	2	hSpCas9	negative selection	8721692
35237905	35237928	6	-	27260156	PATU8988T	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.07070876497475315	[569]	[502,550,596,666]	1	hSpCas9	negative selection	8721693
35232959	35232982	6	-	27260156	PATU8988T	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.1411672441465397	[1255]	[1322,1256,1070,1729]	2	hSpCas9	negative selection	8721694
35231819	35231842	6	-	27260156	PATU8988T	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.4693007143161604	[766]	[413,617,486,638]	-6	hSpCas9	negative selection	8785946
35237937	35237960	6	+	27260156	PATU8988T	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.4365537046022101	[217]	[193,106,150,166]	-6	hSpCas9	negative selection	8785947
35231830	35231853	6	+	27260156	PATU8988T	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.07318229071285931	[943]	[780,912,644,1159]	-1	hSpCas9	negative selection	8785948
35232918	35232941	6	+	27260156	T47D	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	-0.0032286039845459413	[1001]	[1229,1021,1186,1233]	0	hSpCas9	negative selection	8842943
35237905	35237928	6	-	27260156	T47D	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.23779258648960971	[569]	[732,753,860,784]	5	hSpCas9	negative selection	8842944
35232959	35232982	6	-	27260156	T47D	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.12548693105924746	[1255]	[1399,1188,1257,1538]	-3	hSpCas9	negative selection	8842945
35231819	35231842	6	-	27260156	T47D	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.3601394814889718	[766]	[800,660,648,676]	-6	hSpCas9	negative selection	8907197
35237937	35237960	6	+	27260156	T47D	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.19162480851434172	[217]	[261,176,219,234]	-4	hSpCas9	negative selection	8907198
35231830	35231853	6	+	27260156	T47D	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.4293801988630054	[943]	[893,852,808,703]	-7	hSpCas9	negative selection	8907199
35232918	35232941	6	+	27260156	SU8686	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.026760811902652115	[1001]	[896,855,990,1390]	0	hSpCas9	negative selection	8964194
35237905	35237928	6	-	27260156	SU8686	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.04963352916181568	[569]	[551,541,635,621]	0	hSpCas9	negative selection	8964195
35232959	35232982	6	-	27260156	SU8686	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.4877050028419212	[1255]	[734,710,1054,1128]	-7	hSpCas9	negative selection	8964196
35231819	35231842	6	-	27260156	SU8686	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.6403230509950856	[766]	[439,428,515,593]	-7	hSpCas9	negative selection	9028448
35237937	35237960	6	+	27260156	SU8686	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.3019409240953732	[217]	[178,113,261,150]	-5	hSpCas9	negative selection	9028449
35231830	35231853	6	+	27260156	SU8686	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.8489651719261019	[943]	[498,407,510,702]	-8	hSpCas9	negative selection	9028450
35232918	35232941	6	+	27260156	SKES1	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.11489036655016616	[1001]	[1170,1050,967,1131]	2	hSpCas9	negative selection	9085445
35237905	35237928	6	-	27260156	SKES1	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.21887297995821436	[569]	[736,727,563,633]	4	hSpCas9	negative selection	9085446
35232959	35232982	6	-	27260156	SKES1	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	-0.12231956671641586	[1255]	[1061,1270,1343,939]	-3	hSpCas9	negative selection	9085447
35231819	35231842	6	-	27260156	SKES1	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.041318607006680996	[766]	[942,715,698,644]	-1	hSpCas9	negative selection	9149699
35237937	35237960	6	+	27260156	SKES1	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.12637818557480185	[217]	[197,254,201,151]	-3	hSpCas9	negative selection	9149700
35231830	35231853	6	+	27260156	SKES1	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	0.08983890733986999	[943]	[1160,1356,882,699]	2	hSpCas9	negative selection	9149701
35232918	35232941	6	+	27260156	TOV112D	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.2025886039185465	[1001]	[1057,1447,1220,959]	4	hSpCas9	negative selection	9206696
35237905	35237928	6	-	27260156	TOV112D	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.4259801275741107	[569]	[731,923,993,460]	7	hSpCas9	negative selection	9206697
35232959	35232982	6	-	27260156	TOV112D	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.09863812646923598	[1255]	[1513,1579,1449,924]	2	hSpCas9	negative selection	9206698
35231819	35231842	6	-	27260156	TOV112D	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.1687641615447263	[766]	[813,845,605,521]	-3	hSpCas9	negative selection	9270950
35237937	35237960	6	+	27260156	TOV112D	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	-0.6116737522835272	[217]	[126,160,163,122]	-8	hSpCas9	negative selection	9270951
35231830	35231853	6	+	27260156	TOV112D	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.18870101429220576	[943]	[1057,1062,714,564]	-4	hSpCas9	negative selection	9270952
35232918	35232941	6	+	27260156	TC71	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.14803015576457268	[1001]	[1216,1248,1052,1248]	4	hSpCas9	negative selection	9327947
35237905	35237928	6	-	27260156	TC71	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.1852295081075287	[569]	[583,662,751,785]	4	hSpCas9	negative selection	9327948
35232959	35232982	6	-	27260156	TC71	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.08133404481031681	[1255]	[1364,1351,1480,1503]	2	hSpCas9	negative selection	9327949
35231819	35231842	6	-	27260156	TC71	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.16261902172292886	[766]	[782,675,620,868]	-4	hSpCas9	negative selection	9392201
35237937	35237960	6	+	27260156	TC71	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	0.12147359804956304	[217]	[154,234,372,251]	3	hSpCas9	negative selection	9392202
35231830	35231853	6	+	27260156	TC71	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.13414065729400193	[943]	[751,1039,848,1061]	-4	hSpCas9	negative selection	9392203
35232918	35232941	6	+	27260156	TC32	viability	ATTGCCTGTGAATGCCGTCCTGG	SCUBE3	ENSG00000146197	0.06527396753376813	[1001]	[1066,582,1234,1195]	1	hSpCas9	negative selection	9449198
35237905	35237928	6	-	27260156	TC32	viability	GCCCCCGTTGTTGACAGCACAGG	SCUBE3	ENSG00000146197	0.3471074269339622	[569]	[636,417,827,949]	6	hSpCas9	negative selection	9449199
35232959	35232982	6	-	27260156	TC32	viability	TCTCACATTTACAGTCCCGTTGG	SCUBE3	ENSG00000146197	0.02418229347300227	[1255]	[1258,805,1578,1298]	0	hSpCas9	negative selection	9449200
35231819	35231842	6	-	27260156	TC32	viability	AGGTATGCTGGTTGTCGCTGAGG	SCUBE3	ENSG00000146197	-0.05239187129937117	[766]	[643,601,903,662]	-1	hSpCas9	negative selection	9513452
35237937	35237960	6	+	27260156	TC32	viability	AAGTGCCATGATGCAGCGACTGG	SCUBE3	ENSG00000146197	0.12047191761529019	[217]	[204,197,304,192]	2	hSpCas9	negative selection	9513453
35231830	35231853	6	+	27260156	TC32	viability	ACCAGCATACCTGTATCCAGCGG	SCUBE3	ENSG00000146197	-0.14625649446748468	[943]	[754,647,945,902]	-3	hSpCas9	negative selection	9513454
35214482	35214505	6	+	27869803	HPAFII	viability after 27 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	-0.43153163030514824	[367]	[155,132,NaN]	-3	hSpCas9	negative selection	9595622
35228615	35228638	6	+	27869803	HPAFII	viability after 27 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.250985585523015	[567]	[416,303,NaN]	2	hSpCas9	negative selection	9595623
35231790	35231813	6	+	27869803	HPAFII	viability after 27 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-0.9758885352629901	[133]	[73,3,NaN]	-6	hSpCas9	negative selection	9595624
35232892	35232915	6	+	27869803	HPAFII	viability after 27 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	-0.11707205041209467	[348]	[238,110,NaN]	-1	hSpCas9	negative selection	9595625
35233265	35233288	6	+	27869803	HPAFII	viability after 27 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-1.879218837002632	[235]	[48,20,NaN]	-8	hSpCas9	negative selection	9595626
35237903	35237926	6	+	27869803	HPAFII	viability after 27 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.8526024265489054	[437]	[339,478,NaN]	7	hSpCas9	negative selection	9595627
35214482	35214505	6	+	27869803	HPAFII	viability after 15 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.004958072832238702	[367]	[349,425,NaN]	0	hSpCas9	negative selection	9678071
35228615	35228638	6	+	27869803	HPAFII	viability after 15 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	-0.23893694893791817	[567]	[766,361,NaN]	-3	hSpCas9	negative selection	9678072
35231790	35231813	6	+	27869803	HPAFII	viability after 15 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-0.8894402381874681	[133]	[168,20,NaN]	-7	hSpCas9	negative selection	9678073
35232892	35232915	6	+	27869803	HPAFII	viability after 15 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	-0.3761230076590716	[348]	[481,168,NaN]	-4	hSpCas9	negative selection	9678074
35233265	35233288	6	+	27869803	HPAFII	viability after 15 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-1.1197207107766785	[235]	[141,100,NaN]	-8	hSpCas9	negative selection	9678075
35237903	35237926	6	+	27869803	HPAFII	viability after 15 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.678949280674134	[437]	[1056,564,NaN]	7	hSpCas9	negative selection	9678076
35214482	35214505	6	+	27869803	ASPC1	viability after 36 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.08106810312598489	[978]	[794,40,307]	0	hSpCas9	negative selection	9760520
35228615	35228638	6	+	27869803	ASPC1	viability after 36 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.7445917755050254	[1226]	[555,716,823]	7	hSpCas9	negative selection	9760521
35231790	35231813	6	+	27869803	ASPC1	viability after 36 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	1.3239715887117667	[262]	[535,178,52]	9	hSpCas9	negative selection	9760522
35232892	35232915	6	+	27869803	ASPC1	viability after 36 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.4030191643420972	[716]	[459,544,66]	4	hSpCas9	negative selection	9760523
35233265	35233288	6	+	27869803	ASPC1	viability after 36 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.7312484567291865	[625]	[323,338,404]	7	hSpCas9	negative selection	9760524
35237903	35237926	6	+	27869803	ASPC1	viability after 36 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.6556096041007197	[1176]	[783,478,677]	6	hSpCas9	negative selection	9760525
35214482	35214505	6	+	27869803	PATU8988S	viability after 35 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	-0.011863440086072208	[792]	[213,419,NaN]	0	hSpCas9	negative selection	9842969
35228615	35228638	6	+	27869803	PATU8988S	viability after 35 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.3901929681772405	[957]	[357,653,NaN]	4	hSpCas9	negative selection	9842970
35231790	35231813	6	+	27869803	PATU8988S	viability after 35 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	0.2777138287768576	[250]	[143,100,NaN]	3	hSpCas9	negative selection	9842971
35232892	35232915	6	+	27869803	PATU8988S	viability after 35 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.2731481078977209	[758]	[327,410,NaN]	3	hSpCas9	negative selection	9842972
35233265	35233288	6	+	27869803	PATU8988S	viability after 35 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.7587898870983987	[474]	[193,453,NaN]	7	hSpCas9	negative selection	9842973
35237903	35237926	6	+	27869803	PATU8988S	viability after 35 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.4311604224192048	[980]	[627,436,NaN]	5	hSpCas9	negative selection	9842974
35214482	35214505	6	+	27869803	PATU8988S	viability after 31 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	0.4407415212499589	[792]	[349,529,NaN]	5	hSpCas9	negative selection	9925418
35228615	35228638	6	+	27869803	PATU8988S	viability after 31 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.1482356266521957	[957]	[293,587,NaN]	1	hSpCas9	negative selection	9925419
35231790	35231813	6	+	27869803	PATU8988S	viability after 31 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	0.11138540729123525	[250]	[97,120,NaN]	1	hSpCas9	negative selection	9925420
35232892	35232915	6	+	27869803	PATU8988S	viability after 31 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.17664100513897463	[758]	[272,429,NaN]	2	hSpCas9	negative selection	9925421
35233265	35233288	6	+	27869803	PATU8988S	viability after 31 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.5996588052861994	[474]	[158,449,NaN]	7	hSpCas9	negative selection	9925422
35237903	35237926	6	+	27869803	PATU8988S	viability after 31 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.21448114973111154	[980]	[386,538,NaN]	2	hSpCas9	negative selection	9925423
35214482	35214505	6	+	27869803	HPAFII	viability after 35 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	-1.0899039021960109	[367]	[71,104,NaN]	-6	hSpCas9	negative selection	10007867
35228615	35228638	6	+	27869803	HPAFII	viability after 35 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.7216740456312527	[567]	[508,434,NaN]	5	hSpCas9	negative selection	10007868
35231790	35231813	6	+	27869803	HPAFII	viability after 35 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	0.2268366287774214	[133]	[148,0,NaN]	1	hSpCas9	negative selection	10007869
35232892	35232915	6	+	27869803	HPAFII	viability after 35 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.07127942199820281	[348]	[266,93,NaN]	0	hSpCas9	negative selection	10007870
35233265	35233288	6	+	27869803	HPAFII	viability after 35 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-2.3546056559945816	[235]	[36,7,NaN]	-8	hSpCas9	negative selection	10007871
35237903	35237926	6	+	27869803	HPAFII	viability after 35 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	0.9996995771522617	[437]	[377,516,NaN]	6	hSpCas9	negative selection	10007872
35214482	35214505	6	+	27869803	HPAFII	viability after 31 days	CAGTACAGCAAAGCCGCGCAAGG	SCUBE3	ENSG00000146197	-0.719632874326001	[367]	[156,90,NaN]	-5	hSpCas9	negative selection	10090316
35228615	35228638	6	+	27869803	HPAFII	viability after 31 days	CGTGGATGAGTGCGAGCGAGAGG	SCUBE3	ENSG00000146197	0.38930583178721356	[567]	[428,404,NaN]	3	hSpCas9	negative selection	10090317
35231790	35231813	6	+	27869803	HPAFII	viability after 31 days	TATGAGTGCCACTGCCGGGAAGG	SCUBE3	ENSG00000146197	-1.1967799395065368	[133]	[61,0,NaN]	-6	hSpCas9	negative selection	10090318
35232892	35232915	6	+	27869803	HPAFII	viability after 31 days	TTTGCCGGGAGACACCCAAGGGG	SCUBE3	ENSG00000146197	0.13658820613342215	[348]	[266,158,NaN]	1	hSpCas9	negative selection	10090319
35233265	35233288	6	+	27869803	HPAFII	viability after 31 days	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-2.198058230448091	[235]	[36,19,NaN]	-8	hSpCas9	negative selection	10090320
35237903	35237926	6	+	27869803	HPAFII	viability after 31 days	GACCTGTGCTGTCAACAACGGGG	SCUBE3	ENSG00000146197	1.1326873649744855	[437]	[426,660,NaN]	8	hSpCas9	negative selection	10090321
35227681	35227704	6	+	28162770	P31FUJ	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	-0.12409594497187874	[229]	[247]	-1	hSpCas9	negative selection	10230937
35242274	35242297	6	+	28162770	P31FUJ	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	-0.21602649166355187	[341]	[345]	-2	hSpCas9	negative selection	10230938
35244687	35244710	6	-	28162770	P31FUJ	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	-0.028929871048728684	[111]	[128]	0	hSpCas9	negative selection	10230939
35227625	35227648	6	+	28162770	P31FUJ	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.06302213653708455	[144]	[177]	0	hSpCas9	negative selection	10230940
35231724	35231747	6	+	28162770	P31FUJ	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	-0.3168664692028531	[264]	[249]	-3	hSpCas9	negative selection	10230941
35232875	35232898	6	-	28162770	P31FUJ	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	-0.48278045742272635	[43]	[36]	-4	hSpCas9	negative selection	10230942
35233265	35233288	6	+	28162770	P31FUJ	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.08896643184072706	[371]	[410]	-1	hSpCas9	negative selection	10230943
35241146	35241169	6	+	28162770	P31FUJ	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	0.35785140838463336	[252]	[380]	4	hSpCas9	negative selection	10230944
35241550	35241573	6	+	28162770	P31FUJ	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-0.3801439204895656	[617]	[557]	-3	hSpCas9	negative selection	10230945
35241900	35241923	6	-	28162770	P31FUJ	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	-0.31526436460635177	[197]	[186]	-3	hSpCas9	negative selection	10230946
35227681	35227704	6	+	28162770	TF1	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	NaN	[NaN]	[180]	1	hSpCas9	negative selection	10400303
35242274	35242297	6	+	28162770	TF1	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	NaN	[NaN]	[123]	1	hSpCas9	negative selection	10400304
35244687	35244710	6	-	28162770	TF1	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10400305
35227625	35227648	6	+	28162770	TF1	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10400306
35231724	35231747	6	+	28162770	TF1	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	NaN	[NaN]	[210]	1	hSpCas9	negative selection	10400307
35232875	35232898	6	-	28162770	TF1	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10400308
35233265	35233288	6	+	28162770	TF1	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	NaN	[NaN]	[293]	1	hSpCas9	negative selection	10400309
35241146	35241169	6	+	28162770	TF1	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10400310
35241550	35241573	6	+	28162770	TF1	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10400311
35241900	35241923	6	-	28162770	TF1	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10400312
35227681	35227704	6	+	28162770	SKM1	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	0.5909373353728404	[85]	[228]	6	hSpCas9	negative selection	10569669
35242274	35242297	6	+	28162770	SKM1	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	0.4158621320768823	[52]	[124]	4	hSpCas9	negative selection	10569670
35244687	35244710	6	-	28162770	SKM1	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	-0.26128674354752673	[39]	[58]	-2	hSpCas9	negative selection	10569671
35227625	35227648	6	+	28162770	SKM1	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.09226842795211056	[51]	[97]	0	hSpCas9	negative selection	10569672
35231724	35231747	6	+	28162770	SKM1	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	0.20936247288732968	[90]	[185]	2	hSpCas9	negative selection	10569673
35232875	35232898	6	-	28162770	SKM1	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	0.7629608026991506	[9]	[29]	7	hSpCas9	negative selection	10569674
35233265	35233288	6	+	28162770	SKM1	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.3272243107524707	[77]	[172]	3	hSpCas9	negative selection	10569675
35241146	35241169	6	+	28162770	SKM1	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	0.6634251291482361	[44]	[125]	6	hSpCas9	negative selection	10569676
35241550	35241573	6	+	28162770	SKM1	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	0.0524674198941355	[137]	[252]	0	hSpCas9	negative selection	10569677
35241900	35241923	6	-	28162770	SKM1	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	0.10204944874469607	[38]	[73]	1	hSpCas9	negative selection	10569678
35227681	35227704	6	+	28162770	SKM1	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	0.5909373353728404	[85]	[228]	6	hSpCas9	negative selection	10739035
35242274	35242297	6	+	28162770	SKM1	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	0.4158621320768823	[52]	[124]	4	hSpCas9	negative selection	10739036
35244687	35244710	6	-	28162770	SKM1	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	-0.26128674354752673	[39]	[58]	-2	hSpCas9	negative selection	10739037
35227625	35227648	6	+	28162770	SKM1	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.09226842795211056	[51]	[97]	0	hSpCas9	negative selection	10739038
35231724	35231747	6	+	28162770	SKM1	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	0.20936247288732968	[90]	[185]	2	hSpCas9	negative selection	10739039
35232875	35232898	6	-	28162770	SKM1	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	0.7629608026991506	[9]	[29]	7	hSpCas9	negative selection	10739040
35233265	35233288	6	+	28162770	SKM1	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.3272243107524707	[77]	[172]	3	hSpCas9	negative selection	10739041
35241146	35241169	6	+	28162770	SKM1	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	0.6634251291482361	[44]	[125]	6	hSpCas9	negative selection	10739042
35241550	35241573	6	+	28162770	SKM1	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	0.0524674198941355	[137]	[252]	0	hSpCas9	negative selection	10739043
35241900	35241923	6	-	28162770	SKM1	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	0.10204944874469607	[38]	[73]	1	hSpCas9	negative selection	10739044
35227681	35227704	6	+	28162770	PL21	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	0.6274345795234485	[292]	[196]	5	hSpCas9	negative selection	10908401
35242274	35242297	6	+	28162770	PL21	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	1.42142947937861	[186]	[217]	9	hSpCas9	negative selection	10908402
35244687	35244710	6	-	28162770	PL21	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	-0.7592184010133342	[139]	[35]	-5	hSpCas9	negative selection	10908403
35227625	35227648	6	+	28162770	PL21	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.8419479756151861	[140]	[109]	7	hSpCas9	negative selection	10908404
35231724	35231747	6	+	28162770	PL21	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	-0.404722443669541	[291]	[95]	-3	hSpCas9	negative selection	10908405
35232875	35232898	6	-	28162770	PL21	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	-3.5547478876741487	[53]	[1]	-9	hSpCas9	negative selection	10908406
35233265	35233288	6	+	28162770	PL21	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.4909101446215275	[267]	[82]	-4	hSpCas9	negative selection	10908407
35241146	35241169	6	+	28162770	PL21	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	-0.4007644301008576	[181]	[59]	-3	hSpCas9	negative selection	10908408
35241550	35241573	6	+	28162770	PL21	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-0.24670662302019974	[427]	[156]	-2	hSpCas9	negative selection	10908409
35241900	35241923	6	-	28162770	PL21	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	1.324467749491522	[99]	[108]	9	hSpCas9	negative selection	10908410
35227681	35227704	6	+	28162770	P31FUJ	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	-0.12409594497187874	[229]	[247]	-1	hSpCas9	negative selection	11077767
35242274	35242297	6	+	28162770	P31FUJ	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	-0.21602649166355187	[341]	[345]	-2	hSpCas9	negative selection	11077768
35244687	35244710	6	-	28162770	P31FUJ	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	-0.028929871048728684	[111]	[128]	0	hSpCas9	negative selection	11077769
35227625	35227648	6	+	28162770	P31FUJ	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.06302213653708455	[144]	[177]	0	hSpCas9	negative selection	11077770
35231724	35231747	6	+	28162770	P31FUJ	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	-0.3168664692028531	[264]	[249]	-3	hSpCas9	negative selection	11077771
35232875	35232898	6	-	28162770	P31FUJ	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	-0.48278045742272635	[43]	[36]	-4	hSpCas9	negative selection	11077772
35233265	35233288	6	+	28162770	P31FUJ	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.08896643184072706	[371]	[410]	-1	hSpCas9	negative selection	11077773
35241146	35241169	6	+	28162770	P31FUJ	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	0.35785140838463336	[252]	[380]	4	hSpCas9	negative selection	11077774
35241550	35241573	6	+	28162770	P31FUJ	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-0.3801439204895656	[617]	[557]	-3	hSpCas9	negative selection	11077775
35241900	35241923	6	-	28162770	P31FUJ	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	-0.31526436460635177	[197]	[186]	-3	hSpCas9	negative selection	11077776
35227681	35227704	6	+	28162770	OCIAML5	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	0.22849891043967147	[147]	[312]	2	hSpCas9	negative selection	11247133
35242274	35242297	6	+	28162770	OCIAML5	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	-0.7947333957980453	[221]	[230]	-5	hSpCas9	negative selection	11247134
35244687	35244710	6	-	28162770	OCIAML5	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	0.7571434761038365	[58]	[179]	6	hSpCas9	negative selection	11247135
35227625	35227648	6	+	28162770	OCIAML5	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.2702689720600552	[112]	[245]	2	hSpCas9	negative selection	11247136
35231724	35231747	6	+	28162770	OCIAML5	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	-0.024646025752287137	[203]	[361]	0	hSpCas9	negative selection	11247137
35232875	35232898	6	-	28162770	OCIAML5	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	-2.0447116488063926	[15]	[6]	-8	hSpCas9	negative selection	11247138
35233265	35233288	6	+	28162770	OCIAML5	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.19712097876353474	[172]	[357]	1	hSpCas9	negative selection	11247139
35241146	35241169	6	+	28162770	OCIAML5	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	-0.8520665708639971	[142]	[142]	-5	hSpCas9	negative selection	11247140
35241550	35241573	6	+	28162770	OCIAML5	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-0.8330082350483122	[375]	[380]	-5	hSpCas9	negative selection	11247141
35241900	35241923	6	-	28162770	OCIAML5	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	0.9262398186831089	[85]	[294]	7	hSpCas9	negative selection	11247142
35227681	35227704	6	+	28162770	EOL1	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	0.6394788540938252	[540]	[443]	6	hSpCas9	negative selection	11416499
35242274	35242297	6	+	28162770	EOL1	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	-0.5224574563669452	[288]	[105]	-4	hSpCas9	negative selection	11416500
35244687	35244710	6	-	28162770	EOL1	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	-0.32699099542543	[199]	[83]	-2	hSpCas9	negative selection	11416501
35227625	35227648	6	+	28162770	EOL1	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	-0.33437052579102744	[279]	[116]	-3	hSpCas9	negative selection	11416502
35231724	35231747	6	+	28162770	EOL1	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	0.04412938732320715	[485]	[263]	0	hSpCas9	negative selection	11416503
35232875	35232898	6	-	28162770	EOL1	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	-0.7714460415393654	[80]	[24]	-5	hSpCas9	negative selection	11416504
35233265	35233288	6	+	28162770	EOL1	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.4859234519740748	[369]	[272]	4	hSpCas9	negative selection	11416505
35241146	35241169	6	+	28162770	EOL1	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	-0.9244144712806458	[298]	[82]	-6	hSpCas9	negative selection	11416506
35241550	35241573	6	+	28162770	EOL1	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-1.4837323615330005	[567]	[106]	-7	hSpCas9	negative selection	11416507
35241900	35241923	6	-	28162770	EOL1	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	-0.6523774100852031	[178]	[59]	-5	hSpCas9	negative selection	11416508
35227681	35227704	6	+	28162770	MOLM13	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	0.8453386372680576	[417]	[542]	6	hSpCas9	negative selection	11585865
35242274	35242297	6	+	28162770	MOLM13	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	-0.40410300607934957	[387]	[211]	-2	hSpCas9	negative selection	11585866
35244687	35244710	6	-	28162770	MOLM13	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	0.3483077657919064	[175]	[161]	2	hSpCas9	negative selection	11585867
35227625	35227648	6	+	28162770	MOLM13	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.5382787094359767	[199]	[209]	4	hSpCas9	negative selection	11585868
35231724	35231747	6	+	28162770	MOLM13	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	0.5783889228101297	[401]	[433]	4	hSpCas9	negative selection	11585869
35232875	35232898	6	-	28162770	MOLM13	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	0.4492737033772318	[77]	[76]	3	hSpCas9	negative selection	11585870
35233265	35233288	6	+	28162770	MOLM13	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.2871855931733589	[480]	[284]	-2	hSpCas9	negative selection	11585871
35241146	35241169	6	+	28162770	MOLM13	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	-1.3394655405130254	[286]	[81]	-6	hSpCas9	negative selection	11585872
35241550	35241573	6	+	28162770	MOLM13	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-2.151671780700544	[632]	[102]	-7	hSpCas9	negative selection	11585873
35241900	35241923	6	-	28162770	MOLM13	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	-0.7970828285307076	[148]	[61]	-4	hSpCas9	negative selection	11585874
35227681	35227704	6	+	28162770	HEL	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	0.5060501600319766	[353]	[321]	4	hSpCas9	negative selection	11755231
35242274	35242297	6	+	28162770	HEL	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	-0.13363514672408466	[333]	[194]	-1	hSpCas9	negative selection	11755232
35244687	35244710	6	-	28162770	HEL	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	-1.259963966644728	[171]	[45]	-6	hSpCas9	negative selection	11755233
35227625	35227648	6	+	28162770	HEL	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.4308642825779083	[204]	[176]	3	hSpCas9	negative selection	11755234
35231724	35231747	6	+	28162770	HEL	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	0.7401142430449823	[400]	[428]	6	hSpCas9	negative selection	11755235
35232875	35232898	6	-	28162770	HEL	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	-0.10449509761967635	[46]	[27]	-1	hSpCas9	negative selection	11755236
35233265	35233288	6	+	28162770	HEL	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.5709481489323467	[308]	[293]	5	hSpCas9	negative selection	11755237
35241146	35241169	6	+	28162770	HEL	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	-0.08329720200759	[262]	[158]	0	hSpCas9	negative selection	11755238
35241550	35241573	6	+	28162770	HEL	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-1.357261167999643	[531]	[132]	-7	hSpCas9	negative selection	11755239
35241900	35241923	6	-	28162770	HEL	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	-0.2595644941125096	[156]	[83]	-2	hSpCas9	negative selection	11755240
35227681	35227704	6	+	28162770	MV411	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	-0.2639438175572735	[257]	[180]	-2	hSpCas9	negative selection	11924597
35242274	35242297	6	+	28162770	MV411	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	0.43857903813478355	[239]	[273]	4	hSpCas9	negative selection	11924598
35244687	35244710	6	-	28162770	MV411	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	0.14310089096803968	[128]	[119]	1	hSpCas9	negative selection	11924599
35227625	35227648	6	+	28162770	MV411	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.7641153119374567	[136]	[195]	7	hSpCas9	negative selection	11924600
35231724	35231747	6	+	28162770	MV411	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	0.2886602135092883	[275]	[283]	2	hSpCas9	negative selection	11924601
35232875	35232898	6	-	28162770	MV411	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	0.39182746011795033	[37]	[41]	3	hSpCas9	negative selection	11924602
35233265	35233288	6	+	28162770	MV411	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.10248921487167584	[271]	[245]	0	hSpCas9	negative selection	11924603
35241146	35241169	6	+	28162770	MV411	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	-0.6514157257603249	[178]	[95]	-4	hSpCas9	negative selection	11924604
35241550	35241573	6	+	28162770	MV411	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-1.1333067709421907	[387]	[148]	-6	hSpCas9	negative selection	11924605
35241900	35241923	6	-	28162770	MV411	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	0.12613125456064178	[123]	[113]	1	hSpCas9	negative selection	11924606
35227681	35227704	6	+	28162770	MONOMAC1	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	-0.7550323001804407	[211]	[143]	-6	hSpCas9	negative selection	12093963
35242274	35242297	6	+	28162770	MONOMAC1	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	0.46347668666877945	[123]	[195]	4	hSpCas9	negative selection	12093964
35244687	35244710	6	-	28162770	MONOMAC1	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	-0.07150596497569478	[87]	[95]	0	hSpCas9	negative selection	12093965
35227625	35227648	6	+	28162770	MONOMAC1	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.5178059362085126	[91]	[150]	5	hSpCas9	negative selection	12093966
35231724	35231747	6	+	28162770	MONOMAC1	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	1.0219307773192776	[240]	[560]	8	hSpCas9	negative selection	12093967
35232875	35232898	6	-	28162770	MONOMAC1	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	0.9232573866581584	[22]	[49]	8	hSpCas9	negative selection	12093968
35233265	35233288	6	+	28162770	MONOMAC1	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	-0.05081610620850985	[149]	[165]	0	hSpCas9	negative selection	12093969
35241146	35241169	6	+	28162770	MONOMAC1	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	-1.052646937724379	[113]	[62]	-7	hSpCas9	negative selection	12093970
35241550	35241573	6	+	28162770	MONOMAC1	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-0.5890643682918969	[310]	[236]	-5	hSpCas9	negative selection	12093971
35241900	35241923	6	-	28162770	MONOMAC1	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	-0.12577816388973206	[78]	[82]	-1	hSpCas9	negative selection	12093972
35227681	35227704	6	+	28162770	OCIAML2	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	0.1044848895226479	[48]	[291]	1	hSpCas9	negative selection	12263329
35242274	35242297	6	+	28162770	OCIAML2	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	0.04507001304188124	[31]	[182]	0	hSpCas9	negative selection	12263330
35244687	35244710	6	-	28162770	OCIAML2	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	-1.8050488643127205	[28]	[45]	-8	hSpCas9	negative selection	12263331
35227625	35227648	6	+	28162770	OCIAML2	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	-0.11578710788206387	[25]	[132]	-1	hSpCas9	negative selection	12263332
35231724	35231747	6	+	28162770	OCIAML2	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	-0.43558287814296043	[60]	[249]	-3	hSpCas9	negative selection	12263333
35232875	35232898	6	-	28162770	OCIAML2	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	0.14828000740233227	[6]	[42]	1	hSpCas9	negative selection	12263334
35233265	35233288	6	+	28162770	OCIAML2	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.04394334758759686	[34]	[199]	0	hSpCas9	negative selection	12263335
35241146	35241169	6	+	28162770	OCIAML2	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	0.7207962454110733	[36]	[337]	7	hSpCas9	negative selection	12263336
35241550	35241573	6	+	28162770	OCIAML2	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	-1.124854988400431	[71]	[182]	-6	hSpCas9	negative selection	12263337
35241900	35241923	6	-	28162770	OCIAML2	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	-0.040641984497345796	[17]	[96]	0	hSpCas9	negative selection	12263338
35227681	35227704	6	+	28162770	OCIAML3	viability	GGGGACGGCAAACACTGCAAAGG	SCUBE3	ENSG00000146197	2.1476344410515162	[76]	[1029]	9	hSpCas9	negative selection	12432695
35242274	35242297	6	+	28162770	OCIAML3	viability	GCGAAACAAAGGCAAAACAGAGG	SCUBE3	ENSG00000146197	-1.2403706857094627	[71]	[91]	-7	hSpCas9	negative selection	12432696
35244687	35244710	6	-	28162770	OCIAML3	viability	TGGCACAGCGAATACAGCGGTGG	SCUBE3	ENSG00000146197	0.24621191563906764	[30]	[110]	2	hSpCas9	negative selection	12432697
35227625	35227648	6	+	28162770	OCIAML3	viability	CTATCTGCCAGAACACCCCGAGG	SCUBE3	ENSG00000146197	0.20805298206392797	[38]	[135]	2	hSpCas9	negative selection	12432698
35231724	35231747	6	+	28162770	OCIAML3	viability	GATGTGGACGAGTGTGCCGAGGG	SCUBE3	ENSG00000146197	0.30012372456901387	[52]	[196]	3	hSpCas9	negative selection	12432699
35232875	35232898	6	-	28162770	OCIAML3	viability	GGCAAATGTGGGCACAGCCGTGG	SCUBE3	ENSG00000146197	-1.1579085255174897	[16]	[22]	-7	hSpCas9	negative selection	12432700
35233265	35233288	6	+	28162770	OCIAML3	viability	AAGTTTGTGCTCCATACCGACGG	SCUBE3	ENSG00000146197	0.48194121290913544	[73]	[311]	4	hSpCas9	negative selection	12432701
35241146	35241169	6	+	28162770	OCIAML3	viability	GATGAATGCAGCATCAACCGGGG	SCUBE3	ENSG00000146197	0.4556231274004373	[49]	[206]	4	hSpCas9	negative selection	12432702
35241550	35241573	6	+	28162770	OCIAML3	viability	GAAGTGTCAGGGCAGTCCTGGGG	SCUBE3	ENSG00000146197	0.07187485578056041	[103]	[329]	0	hSpCas9	negative selection	12432703
35241900	35241923	6	-	28162770	OCIAML3	viability	GCTGGTGCTTACCATGGCAGTGG	SCUBE3	ENSG00000146197	1.1849654803636185	[21]	[150]	8	hSpCas9	negative selection	12432704