Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4068
• Symbol:SH2D1A
• Description:SH2 domain containing 1A

DataSource: http://genomecrispr.dkfz.de/#!/results/SH2D1A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
124346633	124346656	X	+	26472758	Jiyoye	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.2651563766334456	[159]	[144]	2	hSpCas9	negative selection	146015
124370165	124370188	X	+	26472758	Jiyoye	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	1.1476554598483166	[81]	[136]	7	hSpCas9	negative selection	146016
124346691	124346714	X	+	26472758	Jiyoye	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.3473039255284749	[245]	[235]	2	hSpCas9	negative selection	146017
124346717	124346740	X	+	26472758	Jiyoye	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	-0.9645057485785888	[294]	[113]	-6	hSpCas9	negative selection	146018
124346660	124346683	X	+	26472758	Jiyoye	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.09974685631362612	[197]	[159]	0	hSpCas9	negative selection	146019
124365803	124365826	X	+	26472758	Jiyoye	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	1.068759163829942	[54]	[86]	7	hSpCas9	negative selection	146020
124370230	124370253	X	+	26472758	Jiyoye	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	-0.3863737410267003	[155]	[89]	-3	hSpCas9	negative selection	146021
124346768	124346791	X	-	26472758	Jiyoye	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.5738252509153249	[146]	[164]	4	hSpCas9	negative selection	146022
124365786	124365809	X	+	26472758	Jiyoye	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.16275665383942656	[153]	[129]	1	hSpCas9	negative selection	146023
124370291	124370314	X	-	26472758	Jiyoye	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	-0.08037461755733817	[135]	[96]	0	hSpCas9	negative selection	146024
124346633	124346656	X	+	26472758	KBM7	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.7542390161617423	[498,389]	[390,312]	8	hSpCas9	negative selection	337133
124370165	124370188	X	+	26472758	KBM7	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.7805255156753691	[701,674]	[714,416]	8	hSpCas9	negative selection	337134
124346691	124346714	X	+	26472758	KBM7	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.8338242917480659	[770,587]	[641,494]	8	hSpCas9	negative selection	337135
124346717	124346740	X	+	26472758	KBM7	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.6265686017644195	[404,367]	[354,213]	7	hSpCas9	negative selection	337136
124346660	124346683	X	+	26472758	KBM7	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.23184225297988081	[555,616]	[333,320]	2	hSpCas9	negative selection	337137
124365803	124365826	X	+	26472758	KBM7	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	0.39091960368292117	[378,222]	[255,114]	4	hSpCas9	negative selection	337138
124370230	124370253	X	+	26472758	KBM7	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	0.20356888577514182	[499,512]	[229,316]	2	hSpCas9	negative selection	337139
124346768	124346791	X	-	26472758	KBM7	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.03467862538743682	[617,940]	[503,278]	0	hSpCas9	negative selection	337140
124365786	124365809	X	+	26472758	KBM7	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	-0.059518373191549956	[670,902]	[377,347]	0	hSpCas9	negative selection	337141
124370291	124370314	X	-	26472758	KBM7	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	1.0396736080876854	[547,554]	[733,358]	9	hSpCas9	negative selection	337142
124346633	124346656	X	+	26472758	Raji	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	1.3968901525685844	[179]	[109]	9	hSpCas9	negative selection	528251
124370165	124370188	X	+	26472758	Raji	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.40601154253713256	[386]	[118]	4	hSpCas9	negative selection	528252
124346691	124346714	X	+	26472758	Raji	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.47416586604522204	[303]	[97]	4	hSpCas9	negative selection	528253
124346717	124346740	X	+	26472758	Raji	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.7887010999898914	[221]	[88]	7	hSpCas9	negative selection	528254
124346660	124346683	X	+	26472758	Raji	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	-0.026781702951113068	[258]	[58]	0	hSpCas9	negative selection	528255
124365803	124365826	X	+	26472758	Raji	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	0.9447633345545206	[196]	[87]	8	hSpCas9	negative selection	528256
124370230	124370253	X	+	26472758	Raji	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	1.153187224986724	[216]	[111]	8	hSpCas9	negative selection	528257
124346768	124346791	X	-	26472758	Raji	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.362640590615674	[371]	[110]	3	hSpCas9	negative selection	528258
124365786	124365809	X	+	26472758	Raji	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.9088378559915193	[279]	[121]	8	hSpCas9	negative selection	528259
124370291	124370314	X	-	26472758	Raji	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	0.392785754235848	[255]	[77]	4	hSpCas9	negative selection	528260
124346633	124346656	X	+	26472758	K562	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	1.0614023509218278	[255]	[450]	8	hSpCas9	negative selection	719369
124370165	124370188	X	+	26472758	K562	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.667784586704437	[474]	[636]	5	hSpCas9	negative selection	719370
124346691	124346714	X	+	26472758	K562	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.3385409050309969	[533]	[569]	2	hSpCas9	negative selection	719371
124346717	124346740	X	+	26472758	K562	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.34469595612491843	[388]	[416]	2	hSpCas9	negative selection	719372
124346660	124346683	X	+	26472758	K562	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.8235046620509338	[327]	[489]	7	hSpCas9	negative selection	719373
124365803	124365826	X	+	26472758	K562	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	0.5339253448614318	[260]	[318]	4	hSpCas9	negative selection	719374
124370230	124370253	X	+	26472758	K562	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	1.439729047528673	[337]	[773]	9	hSpCas9	negative selection	719375
124346768	124346791	X	-	26472758	K562	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.9566572359302763	[458]	[751]	7	hSpCas9	negative selection	719376
124365786	124365809	X	+	26472758	K562	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	1.5927191766829436	[682]	[1738]	9	hSpCas9	negative selection	719377
124370291	124370314	X	-	26472758	K562	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	0.5769024176067069	[462]	[582]	5	hSpCas9	negative selection	719378
124346691	124346714	X	+	26627737	DLD1	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	-0.20598236713330076	[53]	[1,24,16]	-2	hSpCas9	negative selection	844324
124346707	124346730	X	-	26627737	DLD1	viability	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.6459359218143866	[254]	[132,93,142]	6	hSpCas9	negative selection	844325
124365786	124365809	X	+	26627737	DLD1	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.7486593198533519	[897]	[289,542,569]	7	hSpCas9	negative selection	844326
124346691	124346714	X	+	26627737	GBM cells	viability after 5 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.7963441412451377	[50]	[37,56]	9	hSpCas9	negative selection	926639
124346707	124346730	X	-	26627737	GBM cells	viability after 5 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.4838763756068417	[157]	[139,96]	7	hSpCas9	negative selection	926640
124365786	124365809	X	+	26627737	GBM cells	viability after 5 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.08955937518173296	[721]	[393,429]	1	hSpCas9	negative selection	926641
124346691	124346714	X	+	26627737	GBM cells	viability after 13 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	1.041078177631207	[50]	[78,38]	9	hSpCas9	negative selection	1008954
124346707	124346730	X	-	26627737	GBM cells	viability after 13 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.483089799116893	[157]	[110,126]	6	hSpCas9	negative selection	1008955
124365786	124365809	X	+	26627737	GBM cells	viability after 13 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.3597977550627234	[721]	[596,425]	4	hSpCas9	negative selection	1008956
124346691	124346714	X	+	26627737	GBM cells	viability after 21 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	1.0527403375182434	[50]	[57,56]	9	hSpCas9	negative selection	1091269
124346707	124346730	X	-	26627737	GBM cells	viability after 21 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.2609284617264762	[157]	[117,88]	2	hSpCas9	negative selection	1091270
124365786	124365809	X	+	26627737	GBM cells	viability after 21 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.2488395833269339	[721]	[510,424]	2	hSpCas9	negative selection	1091271
124346691	124346714	X	+	26627737	RPE1	viability after 9 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	1.3405555021446176	[160]	[107,152]	7	hSpCas9	negative selection	1173584
124346707	124346730	X	-	26627737	RPE1	viability after 9 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	-0.2328498320377299	[328]	[36,152]	-2	hSpCas9	negative selection	1173585
124365786	124365809	X	+	26627737	RPE1	viability after 9 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.5529276754622316	[2169]	[952,1052]	4	hSpCas9	negative selection	1173586
124346691	124346714	X	+	26627737	RPE1	viability after 12 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	1.3299713628875762	[160]	[65,153]	7	hSpCas9	negative selection	1255899
124346707	124346730	X	-	26627737	RPE1	viability after 12 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	-0.500377873958977	[328]	[27,98]	-3	hSpCas9	negative selection	1255900
124365786	124365809	X	+	26627737	RPE1	viability after 12 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.545550528842097	[2169]	[882,816]	3	hSpCas9	negative selection	1255901
124346691	124346714	X	+	26627737	RPE1	viability after 15 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	1.5891737696153956	[160]	[50,219]	8	hSpCas9	negative selection	1338214
124346707	124346730	X	-	26627737	RPE1	viability after 15 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	-0.13122642763607084	[328]	[1,164]	-1	hSpCas9	negative selection	1338215
124365786	124365809	X	+	26627737	RPE1	viability after 15 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.5920024797191525	[2169]	[1134,722]	4	hSpCas9	negative selection	1338216
124346691	124346714	X	+	26627737	RPE1	viability after 18 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.5959795248491333	[160]	[26,106]	4	hSpCas9	negative selection	1420529
124346707	124346730	X	-	26627737	RPE1	viability after 18 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	-0.23382549411103004	[328]	[60,90]	-1	hSpCas9	negative selection	1420530
124365786	124365809	X	+	26627737	RPE1	viability after 18 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.6797788250670382	[2169]	[1071,794]	4	hSpCas9	negative selection	1420531
124346691	124346714	X	+	26627737	HeLa	viability after 8 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	6.866728191541345	[0]	[174,2,4]	9	hSpCas9	negative selection	1502844
124346707	124346730	X	-	26627737	HeLa	viability after 8 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.47659702516283126	[243]	[88,307,40]	4	hSpCas9	negative selection	1502845
124365786	124365809	X	+	26627737	HeLa	viability after 8 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.6848697595969025	[747]	[557,505,513]	6	hSpCas9	negative selection	1502846
124346691	124346714	X	+	26627737	HeLa	viability after 12 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	5.763476858603365	[0]	[11,3,52]	9	hSpCas9	negative selection	1585159
124346707	124346730	X	-	26627737	HeLa	viability after 12 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.5451484617123747	[243]	[107,111,223]	4	hSpCas9	negative selection	1585160
124365786	124365809	X	+	26627737	HeLa	viability after 12 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.9190893023296919	[747]	[622,609,518]	7	hSpCas9	negative selection	1585161
124346691	124346714	X	+	26627737	HeLa	viability after 15 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	5.388234313415814	[0]	[21,0,28]	9	hSpCas9	negative selection	1667474
124346707	124346730	X	-	26627737	HeLa	viability after 15 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	-0.7111395480919825	[243]	[47,99,31]	-6	hSpCas9	negative selection	1667475
124365786	124365809	X	+	26627737	HeLa	viability after 15 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.3551103915325565	[747]	[303,434,433]	3	hSpCas9	negative selection	1667476
124346691	124346714	X	+	26627737	HeLa	viability after 18 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	5.315814168438987	[0]	[12,0,28]	9	hSpCas9	negative selection	1749789
124346707	124346730	X	-	26627737	HeLa	viability after 18 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	-0.6778921278958904	[243]	[33,83,31]	-5	hSpCas9	negative selection	1749790
124365786	124365809	X	+	26627737	HeLa	viability after 18 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.38726002460002873	[747]	[213,368,433]	3	hSpCas9	negative selection	1749791
124346691	124346714	X	+	26627737	HCT116	viability after 6 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.7932463796154283	[30]	[1,11]	4	hSpCas9	negative selection	1832104
124346707	124346730	X	-	26627737	HCT116	viability after 6 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.26255962951320944	[364]	[131,33]	1	hSpCas9	negative selection	1832105
124365786	124365809	X	+	26627737	HCT116	viability after 6 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.2643180393269169	[1289]	[541,78]	1	hSpCas9	negative selection	1832106
124346691	124346714	X	+	26627737	HCT116	viability after 8 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	-1.0783682115899045	[134]	[47,29,27]	-8	hSpCas9	negative selection	1914419
124346707	124346730	X	-	26627737	HCT116	viability after 8 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.007155621356260675	[273]	[119,130,202]	0	hSpCas9	negative selection	1914420
124365786	124365809	X	+	26627737	HCT116	viability after 8 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.9455700083218852	[458]	[444,479,534]	8	hSpCas9	negative selection	1914421
124346691	124346714	X	+	26627737	HCT116	viability after 9 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	-0.5444143469962341	[30]	[3,6]	-4	hSpCas9	negative selection	1996734
124346707	124346730	X	-	26627737	HCT116	viability after 9 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.1947780351791455	[364]	[91,126]	1	hSpCas9	negative selection	1996735
124365786	124365809	X	+	26627737	HCT116	viability after 9 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.744734929078414	[1289]	[603,555]	5	hSpCas9	negative selection	1996736
124346691	124346714	X	+	26627737	HCT116	viability after 12 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	-0.8910913816642778	[134]	[12,38,64]	-7	hSpCas9	negative selection	2079049
124346707	124346730	X	-	26627737	HCT116	viability after 12 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	-0.030323294050948912	[273]	[48,178,203]	0	hSpCas9	negative selection	2079050
124365786	124365809	X	+	26627737	HCT116	viability after 12 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	1.080958579143834	[458]	[542,552,432]	8	hSpCas9	negative selection	2079051
124346691	124346714	X	+	26627737	HCT116	viability after 15 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.10448950206185659	[134]	[23,148,69]	1	hSpCas9	negative selection	2161364
124346707	124346730	X	-	26627737	HCT116	viability after 15 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.41914358018812947	[273]	[231,203,197]	4	hSpCas9	negative selection	2161365
124365786	124365809	X	+	26627737	HCT116	viability after 15 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	1.0448628131579207	[458]	[612,567,459]	8	hSpCas9	negative selection	2161366
124346691	124346714	X	+	26627737	HCT116	viability after 18 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	-0.2704871064828134	[134]	[30,14,121]	-2	hSpCas9	negative selection	2243679
124346707	124346730	X	-	26627737	HCT116	viability after 18 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.9147219208743876	[273]	[244,295,202]	7	hSpCas9	negative selection	2243680
124365786	124365809	X	+	26627737	HCT116	viability after 18 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	1.3031808933593325	[458]	[534,610,489]	8	hSpCas9	negative selection	2243681
124360019	124360042	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCGGGAGGCTGGAG	SH2D1A	ENSG00000183918	-0.4892893999709095	[44,388]	[14,54]	-2	dCas9-VP64	positive selection	2465817
124360019	124360042	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCGGGAGGCTGGAG	SH2D1A	ENSG00000183918	-0.16148281958930955	[134,276]	[52,65]	-1	dCas9-VP64	positive selection	2561072
124346693	124346716	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAAGCTCCTGCTTGCCACTGGG	SH2D1A	ENSG00000183918	0.2522420943617044	[5,5]	[5,6]	5	hSpCas9	positive selection	3019983
124346707	124346730	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.25902049276851585	[4,4]	[4,4]	5	hSpCas9	positive selection	3019984
124346718	124346741	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	-0.33190076739920493	[3,3]	[3,1]	-5	hSpCas9	positive selection	3019985
124346661	124346684	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	-0.012741891792976329	[4,4]	[3,3]	0	hSpCas9	positive selection	3019986
124346693	124346716	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAAGCTCCTGCTTGCCACTGGG	SH2D1A	ENSG00000183918	-0.06655885083578639	[5,5]	[5,2]	-1	hSpCas9	positive selection	3087841
124346707	124346730	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	-0.058269651067036965	[4,4]	[4,2]	-1	hSpCas9	positive selection	3087842
124346718	124346741	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	-0.397728562592525	[3,3]	[1,1]	-6	hSpCas9	positive selection	3087843
124346661	124346684	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	-0.5375416491488193	[4,4]	[3,0]	-7	hSpCas9	positive selection	3087844
124365794	124365817		-	24336571	A375	resistance to PLX after 7 days	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	-0.06048208925360843	[35,33]	[32,32]	-2	hSpCas9	positive selection	3143899
124371376	124371399		-	24336571	A375	resistance to PLX after 7 days	TTTTTCTTCATGGGGCTTTCAGG	SH2D1A	ENSG00000183918	-0.08634637820442853	[10,10]	[10,9]	-3	hSpCas9	positive selection	3143900
124365794	124365817		-	24336571	A375	resistance to PLX after 14 days	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	-0.4285382317066404	[33,31]	[10,10]	-5	hSpCas9	positive selection	3201692
124371376	124371399		-	24336571	A375	resistance to PLX after 14 days	TTTTTCTTCATGGGGCTTTCAGG	SH2D1A	ENSG00000183918	-0.8591351877195946	[10,15]	[3,2]	-8	hSpCas9	positive selection	3201693
124365794	124365817		-	24336571	A375	viability after 7 days	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.46672880024759145	[25]	[35,33]	7	hSpCas9	negative selection	3259485
124371376	124371399		-	24336571	A375	viability after 7 days	TTTTTCTTCATGGGGCTTTCAGG	SH2D1A	ENSG00000183918	-0.3212959983094701	[14]	[10,10]	-4	hSpCas9	negative selection	3259486
124365794	124365817		-	24336571	A375	viability after 14 days	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.4096847467130852	[25]	[33,31]	5	hSpCas9	negative selection	3317278
124371376	124371399		-	24336571	A375	viability after 14 days	TTTTTCTTCATGGGGCTTTCAGG	SH2D1A	ENSG00000183918	-0.031398641432779026	[14]	[10,15]	0	hSpCas9	negative selection	3317279
124370290	124370313	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	1.2800462879459185	[62,62]	[0,0]	5	hSpCas9	positive selection	3392195
124370263	124370286	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.4569193062202875	[209,209]	[0,0]	-3	hSpCas9	positive selection	3392196
124365794	124365817	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	4.099324377379341	[240,240]	[26,26]	9	hSpCas9	positive selection	3392197
124346692	124346715	X	+	26780180	HT29	viability (Avana library 4 designs)	AGAAGCTCCTGCTTGCCACTGGG	SH2D1A	ENSG00000183918	-0.578236600225937	[]	[]	-8	hSpCas9	negative selection	3458487
124346707	124346730	X	-	26780180	HT29	viability (Avana library 4 designs)	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	-0.860448421000967	[]	[]	-9	hSpCas9	negative selection	3458488
124346717	124346740	X	+	26780180	HT29	viability (Avana library 4 designs)	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.700678876776594	[]	[]	2	hSpCas9	negative selection	3458489
124346660	124346683	X	+	26780180	HT29	viability (Avana library 4 designs)	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	-0.13575525389288	[]	[]	-2	hSpCas9	negative selection	3458490
124346660	124346683	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.847303400844883	[]	[]	1	hSpCas9	negative selection	3557952
124346707	124346730	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	3.77029016756739	[]	[]	6	hSpCas9	negative selection	3557953
124346692	124346715	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGCTCCTGCTTGCCACTGGG	SH2D1A	ENSG00000183918	7.02900458107977	[]	[]	9	hSpCas9	negative selection	3557954
124346717	124346740	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	5.78918945860383	[]	[]	9	hSpCas9	negative selection	3557955
124346768	124346791	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	-6.594417284648	[]	[]	-6	hSpCas9	negative selection	3557956
124346686	124346709	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCAAGCAGGAGCTTCTCGCCGG	SH2D1A	ENSG00000183918	0.479930415535448	[]	[]	0	hSpCas9	negative selection	3557957
124346660	124346683	X	+	26780180	A375	viability (Avana lentiGuide)	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	-1.25953088233288	[]	[]	-2	hSpCas9	negative selection	3666611
124346707	124346730	X	-	26780180	A375	viability (Avana lentiGuide)	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	-5.49544209970995	[]	[]	-8	hSpCas9	negative selection	3666612
124346692	124346715	X	+	26780180	A375	viability (Avana lentiGuide)	AGAAGCTCCTGCTTGCCACTGGG	SH2D1A	ENSG00000183918	-0.252197912313401	[]	[]	0	hSpCas9	negative selection	3666613
124346717	124346740	X	+	26780180	A375	viability (Avana lentiGuide)	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.636962567105414	[]	[]	0	hSpCas9	negative selection	3666614
124346768	124346791	X	-	26780180	A375	viability (Avana lentiGuide)	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	-3.34007775950085	[]	[]	-6	hSpCas9	negative selection	3666615
124346686	124346709	X	-	26780180	A375	viability (Avana lentiGuide)	GGCAAGCAGGAGCTTCTCGCCGG	SH2D1A	ENSG00000183918	1.75242698847209	[]	[]	2	hSpCas9	negative selection	3666616
124346660	124346683	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	-0.04463964016164948	[5]	[6,4]	0	hSpCas9	positive selection	3775218
124346707	124346730	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.05909436257021691	[5]	[7,4]	1	hSpCas9	positive selection	3775219
124346692	124346715	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGCTCCTGCTTGCCACTGGG	SH2D1A	ENSG00000183918	0.29075484312320815	[6]	[7,7]	8	hSpCas9	positive selection	3775220
124346717	124346740	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.26783497405480733	[5]	[6,6]	7	hSpCas9	positive selection	3775221
124346768	124346791	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	-0.4404190334349915	[7]	[5,4]	-6	hSpCas9	positive selection	3775222
124346686	124346709	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCAAGCAGGAGCTTCTCGCCGG	SH2D1A	ENSG00000183918	-0.35706450287996133	[4]	[2,3]	-5	hSpCas9	positive selection	3775223
124346660	124346683	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.07278809264081855	[5]	[4,5]	1	hSpCas9	positive selection	3883825
124346707	124346730	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.2411318576777576	[6]	[7,5]	6	hSpCas9	positive selection	3883826
124346692	124346715	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGCTCCTGCTTGCCACTGGG	SH2D1A	ENSG00000183918	0.3326264398821883	[7]	[8,7]	8	hSpCas9	positive selection	3883827
124346717	124346740	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.03435160305314186	[5]	[3,5]	0	hSpCas9	positive selection	3883828
124346768	124346791	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.31480431061594416	[7]	[7,7]	8	hSpCas9	positive selection	3883829
124346686	124346709	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCAAGCAGGAGCTTCTCGCCGG	SH2D1A	ENSG00000183918	0.2750693187161574	[4]	[5,4]	7	hSpCas9	positive selection	3883830
124346641	124346664	X	-	26780180	A375	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.628712578179922	[]	[]	2	hSpCas9	negative selection	3993868
124365786	124365809	X	+	26780180	A375	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	1.22692056158666	[]	[]	6	hSpCas9	negative selection	3993869
124365794	124365817	X	-	26780180	A375	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.552959468997668	[]	[]	1	hSpCas9	negative selection	3993870
124370290	124370313	X	+	26780180	A375	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	1.25518965037496	[]	[]	6	hSpCas9	negative selection	3993871
124346659	124346682	X	+	26780180	A375	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	1.29470035583517	[]	[]	7	hSpCas9	negative selection	3993872
124370263	124370286	X	-	26780180	A375	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	1.00774433653109	[]	[]	4	hSpCas9	negative selection	3993873
124346641	124346664	X	-	26780180	HT29	viability (GeCKOv2 library)	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	1.04154304474466	[]	[]	5	hSpCas9	negative selection	4101834
124365786	124365809	X	+	26780180	HT29	viability (GeCKOv2 library)	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	1.54776258485201	[]	[]	7	hSpCas9	negative selection	4101835
124365794	124365817	X	-	26780180	HT29	viability (GeCKOv2 library)	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.693224494832791	[]	[]	2	hSpCas9	negative selection	4101836
124370290	124370313	X	+	26780180	HT29	viability (GeCKOv2 library)	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.547678097800675	[]	[]	1	hSpCas9	negative selection	4101837
124346659	124346682	X	+	26780180	HT29	viability (GeCKOv2 library)	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.913685324481937	[]	[]	4	hSpCas9	negative selection	4101838
124370263	124370286	X	-	26780180	HT29	viability (GeCKOv2 library)	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.508131633604049	[]	[]	1	hSpCas9	negative selection	4101839
124365794	124365817	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.17089597188743905	[4]	[3,3]	4	hSpCas9	positive selection	4169815
124371376	124371399	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTTTCTTCATGGGGCTTTCAGG	SH2D1A	ENSG00000183918	-0.005879079985375901	[3]	[2,1]	0	hSpCas9	positive selection	4169816
124365794	124365817	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	1.0470144048637047	[3]	[0,3,4,3]	7	hSpCas9	positive selection	4233837
124371376	124371399	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTTTCTTCATGGGGCTTTCAGG	SH2D1A	ENSG00000183918	0.03234541269566091	[2]	[3,0,0,0]	0	hSpCas9	positive selection	4233838
124346641	124346664	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.24914383667463402	[3]	[3,3]	5	hSpCas9	positive selection	4297513
124365786	124365809	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.16301459052720085	[2]	[3,1]	3	hSpCas9	positive selection	4297514
124346659	124346682	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.19197119686861658	[2]	[2,2]	4	hSpCas9	positive selection	4297515
124370290	124370313	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.14817806934050726	[2]	[3,1]	3	hSpCas9	positive selection	4361767
124370263	124370286	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.2784699132392176	[3]	[4,2]	5	hSpCas9	positive selection	4361768
124365794	124365817	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.6260171412814629	[3]	[3,4]	9	hSpCas9	positive selection	4361769
124346718	124346740	X	+	27760321	OCIAML3	viability	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.6557907912228239	[492,372]	[523,535]	7	hSpCas9	negative selection	4438573
124346754	124346776	X	-	27760321	OCIAML3	viability	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	-0.4687698473605856	[610,534]	[257,407]	-5	hSpCas9	negative selection	4438574
124365794	124365816	X	-	27760321	OCIAML3	viability	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.11969268690819446	[663,524]	[379,660]	1	hSpCas9	negative selection	4438575
124370166	124370188	X	+	27760321	OCIAML3	viability	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.870704565916924	[372,348]	[450,601]	8	hSpCas9	negative selection	4438576
124370182	124370204	X	-	27760321	OCIAML3	viability	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	0.25420190380447494	[189,171]	[169,166]	3	hSpCas9	negative selection	4438577
124346718	124346740	X	+	27760321	OCIAML2	viability	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.407493577516958	[492,372]	[399,540]	5	hSpCas9	negative selection	4522036
124346754	124346776	X	-	27760321	OCIAML2	viability	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	0.20944049210459226	[610,534]	[438,660]	2	hSpCas9	negative selection	4522037
124365794	124365816	X	-	27760321	OCIAML2	viability	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.23111149619733407	[663,524]	[509,627]	3	hSpCas9	negative selection	4522038
124370166	124370188	X	+	27760321	OCIAML2	viability	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.5650557854085383	[372,348]	[389,487]	7	hSpCas9	negative selection	4522039
124370182	124370204	X	-	27760321	OCIAML2	viability	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	1.050827795309059	[189,171]	[287,322]	9	hSpCas9	negative selection	4522040
124346718	124346740	X	+	27760321	MV411	viability	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	2.2887572703570775	[492,372]	[1764,813]	9	hSpCas9	negative selection	4605499
124346754	124346776	X	-	27760321	MV411	viability	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	-0.49564843307672857	[610,534]	[28,625]	-3	hSpCas9	negative selection	4605500
124365794	124365816	X	-	27760321	MV411	viability	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	1.475895898788753	[663,524]	[1023,1174]	9	hSpCas9	negative selection	4605501
124370166	124370188	X	+	27760321	MV411	viability	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	-0.040306759895714084	[372,348]	[218,250]	0	hSpCas9	negative selection	4605502
124370182	124370204	X	-	27760321	MV411	viability	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	-0.09945791503026524	[189,171]	[106,117]	0	hSpCas9	negative selection	4605503
124346718	124346740	X	+	27760321	HL60	viability	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.4785758370884472	[492,372]	[566,405]	6	hSpCas9	negative selection	4688962
124346754	124346776	X	-	27760321	HL60	viability	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	-0.034348592283197754	[610,534]	[474,435]	0	hSpCas9	negative selection	4688963
124365794	124365816	X	-	27760321	HL60	viability	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.5911728005614332	[663,524]	[692,762]	7	hSpCas9	negative selection	4688964
124370166	124370188	X	+	27760321	HL60	viability	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.8610838966280211	[372,348]	[533,537]	8	hSpCas9	negative selection	4688965
124370182	124370204	X	-	27760321	HL60	viability	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	-0.6941912356409703	[189,171]	[84,97]	-6	hSpCas9	negative selection	4688966
124346718	124346740	X	+	27760321	HT1080	viability	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	1.4188549602073914	[372,290]	[197,523]	7	hSpCas9	negative selection	4772425
124346754	124346776	X	-	27760321	HT1080	viability	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	-0.22247664454070906	[534,417]	[145,180]	-1	hSpCas9	negative selection	4772426
124365794	124365816	X	-	27760321	HT1080	viability	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	1.2561255925839623	[524,409]	[230,678]	6	hSpCas9	negative selection	4772427
124370166	124370188	X	+	27760321	HT1080	viability	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	1.5199343479723366	[348,272]	[309,404]	8	hSpCas9	negative selection	4772428
124370182	124370204	X	-	27760321	HT1080	viability	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	1.8122906772134644	[171,133]	[140,293]	8	hSpCas9	negative selection	4772429
124346718	124346740	X	+	27760321	HT29	viability after 7 days	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.3058722543355086	[372,290]	[451,705,416]	5	hSpCas9	negative selection	4855888
124346754	124346776	X	-	27760321	HT29	viability after 7 days	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	-0.02417054877033087	[534,417]	[708,515,596]	0	hSpCas9	negative selection	4855889
124365794	124365816	X	-	27760321	HT29	viability after 7 days	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.37813682445146	[524,409]	[676,752,893]	6	hSpCas9	negative selection	4855890
124370166	124370188	X	+	27760321	HT29	viability after 7 days	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	-0.13634391355028752	[348,272]	[452,358,293]	-2	hSpCas9	negative selection	4855891
124370182	124370204	X	-	27760321	HT29	viability after 7 days	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	-1.0139663484869417	[171,133]	[183,41,78]	-8	hSpCas9	negative selection	4855892
124346718	124346740	X	+	27760321	HT29	viability after 25 days	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.3444380423846643	[372,290]	[434,619,381]	3	hSpCas9	negative selection	4939351
124346754	124346776	X	-	27760321	HT29	viability after 25 days	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	0.2911044006806509	[534,417]	[719,501,784]	3	hSpCas9	negative selection	4939352
124365794	124365816	X	-	27760321	HT29	viability after 25 days	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.7076924669411299	[524,409]	[777,785,1079]	7	hSpCas9	negative selection	4939353
124370166	124370188	X	+	27760321	HT29	viability after 25 days	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	-0.20465357889260655	[348,272]	[272,320,335]	-2	hSpCas9	negative selection	4939354
124370182	124370204	X	-	27760321	HT29	viability after 25 days	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	-0.49021750027763256	[171,133]	[93,62,228]	-4	hSpCas9	negative selection	4939355
124346718	124346740	X	+	27760321	HT29	viability after 22 days	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.3447238965042504	[372,290]	[429,514,518]	3	hSpCas9	negative selection	5022814
124346754	124346776	X	-	27760321	HT29	viability after 22 days	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	0.032853458334375585	[534,417]	[573,494,621]	0	hSpCas9	negative selection	5022815
124365794	124365816	X	-	27760321	HT29	viability after 22 days	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.7562447963449584	[524,409]	[929,709,1099]	8	hSpCas9	negative selection	5022816
124370166	124370188	X	+	27760321	HT29	viability after 22 days	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	-0.2676699913418062	[348,272]	[166,393,338]	-3	hSpCas9	negative selection	5022817
124370182	124370204	X	-	27760321	HT29	viability after 22 days	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	-0.23170799022489508	[171,133]	[114,61,276]	-2	hSpCas9	negative selection	5022818
124346718	124346740	X	+	27760321	HT29	viability after 19 days	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	-0.11444805921642964	[372,290]	[444,216,397]	-1	hSpCas9	negative selection	5106277
124346754	124346776	X	-	27760321	HT29	viability after 19 days	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	0.017372740505745887	[534,417]	[580,698,383]	0	hSpCas9	negative selection	5106278
124365794	124365816	X	-	27760321	HT29	viability after 19 days	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.4912676034511869	[524,409]	[822,478,951]	5	hSpCas9	negative selection	5106279
124370166	124370188	X	+	27760321	HT29	viability after 19 days	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	-0.48660296679791665	[348,272]	[151,295,300]	-4	hSpCas9	negative selection	5106280
124370182	124370204	X	-	27760321	HT29	viability after 19 days	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	0.5490669664406239	[171,133]	[178,250,326]	5	hSpCas9	negative selection	5106281
124346718	124346740	X	+	27760321	HT29	viability after 16 days	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	-0.11431137624805068	[372,290]	[366,519,139]	-1	hSpCas9	negative selection	5189740
124346754	124346776	X	-	27760321	HT29	viability after 16 days	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	-0.211380128542191	[534,417]	[678,422,300]	-2	hSpCas9	negative selection	5189741
124365794	124365816	X	-	27760321	HT29	viability after 16 days	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.7543433677920833	[524,409]	[990,618,1053]	8	hSpCas9	negative selection	5189742
124370166	124370188	X	+	27760321	HT29	viability after 16 days	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.04470638292609774	[348,272]	[273,349,444]	0	hSpCas9	negative selection	5189743
124370182	124370204	X	-	27760321	HT29	viability after 16 days	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	-1.0753016520053216	[171,133]	[87,92,62]	-7	hSpCas9	negative selection	5189744
124346718	124346740	X	+	27760321	HT29	viability after 13 days	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.38936075964641487	[372,290]	[664,514,342]	5	hSpCas9	negative selection	5273203
124346754	124346776	X	-	27760321	HT29	viability after 13 days	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	0.1043530940131715	[534,417]	[669,456,651]	1	hSpCas9	negative selection	5273204
124365794	124365816	X	-	27760321	HT29	viability after 13 days	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.5059010728375969	[524,409]	[823,728,757]	6	hSpCas9	negative selection	5273205
124370166	124370188	X	+	27760321	HT29	viability after 13 days	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.1467799889923588	[348,272]	[546,318,335]	1	hSpCas9	negative selection	5273206
124370182	124370204	X	-	27760321	HT29	viability after 13 days	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	-0.2886150402333236	[171,133]	[198,146,92]	-4	hSpCas9	negative selection	5273207
124346718	124346740	X	+	27760321	HT29	viability after 10 days	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.39154654034637704	[372,290]	[554,414,654]	5	hSpCas9	negative selection	5356666
124346754	124346776	X	-	27760321	HT29	viability after 10 days	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	0.1462501482378904	[534,417]	[645,678,650]	2	hSpCas9	negative selection	5356667
124365794	124365816	X	-	27760321	HT29	viability after 10 days	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.2849275001293149	[524,409]	[589,716,823]	4	hSpCas9	negative selection	5356668
124370166	124370188	X	+	27760321	HT29	viability after 10 days	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	-0.2529760859598206	[348,272]	[303,262,406]	-3	hSpCas9	negative selection	5356669
124370182	124370204	X	-	27760321	HT29	viability after 10 days	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	-0.2874069079963597	[171,133]	[186,152,129]	-4	hSpCas9	negative selection	5356670
124346718	124346740	X	+	27760321	MOLM13	viability	GATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	2.2317102259120234	[492,372]	[1431,887]	9	hSpCas9	negative selection	5440129
124346754	124346776	X	-	27760321	MOLM13	viability	CACATAGGCAGTACACGCCTGG	SH2D1A	ENSG00000183918	1.4399766274404509	[610,534]	[851,894]	8	hSpCas9	negative selection	5440130
124365794	124365816	X	-	27760321	MOLM13	viability	CCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.7322642207446532	[663,524]	[530,572]	5	hSpCas9	negative selection	5440131
124370166	124370188	X	+	27760321	MOLM13	viability	TATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.890539844209325	[372,348]	[393,363]	6	hSpCas9	negative selection	5440132
124370182	124370204	X	-	27760321	MOLM13	viability	AATATCTTTTATGTACCCCAGG	SH2D1A	ENSG00000183918	-0.2431282376305386	[189,171]	[42,122]	-2	hSpCas9	negative selection	5440133
124346568	124346591	X	+	27661255	K562	viability	GTGCCTGGCTGCAGTAGCAGCGG	SH2D1A	ENSG00000183918	0.14780972509693036	[943,1159]	[953,904]	5	dCas9-KRAB	negative selection	5510708
124346614	124346637	X	-	27661255	K562	viability	GTGGACTCTTGGGCAGGCCGAGG	SH2D1A	ENSG00000183918	-0.01645095089358728	[361,331]	[328,227]	0	dCas9-KRAB	negative selection	5510709
124346900	124346923	X	-	27661255	K562	viability	GACTTGAGGGTGGGCCACGGAGG	SH2D1A	ENSG00000183918	-0.0021680598168612453	[916,983]	[842,683]	0	dCas9-KRAB	negative selection	5510710
124346961	124346984	X	-	27661255	K562	viability	GGGAATGAAATCCCCAGCGAGGG	SH2D1A	ENSG00000183918	0.999258077951815	[13,55]	[31,73]	9	dCas9-KRAB	negative selection	5510711
124346641	124346664	X	-	27260156	BXPC3	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.10933611542977639	[926]	[1162,1119,835,1032]	2	hSpCas9	negative selection	5569973
124365786	124365809	X	+	27260156	BXPC3	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.37033414141741017	[346]	[468,485,390,531]	7	hSpCas9	negative selection	5569974
124346659	124346682	X	+	27260156	BXPC3	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.15313730687113974	[344]	[335,385,423,472]	3	hSpCas9	negative selection	5569975
124370290	124370313	X	+	27260156	BXPC3	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	-0.02357874328591275	[378]	[324,323,425,507]	0	hSpCas9	negative selection	5634227
124370263	124370286	X	-	27260156	BXPC3	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.06658659536713118	[756]	[828,921,763,781]	1	hSpCas9	negative selection	5634228
124365794	124365817	X	-	27260156	BXPC3	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.29866347991517306	[459]	[621,501,617,626]	6	hSpCas9	negative selection	5634229
124346641	124346664	X	-	27260156	A673	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.13613367689629952	[926]	[975,1060,1154,840]	-3	hSpCas9	negative selection	5691224
124365786	124365809	X	+	27260156	A673	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.13272632323579625	[346]	[587,382,382,491]	3	hSpCas9	negative selection	5691225
124346659	124346682	X	+	27260156	A673	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.17129128857605913	[344]	[503,428,517,415]	4	hSpCas9	negative selection	5691226
124370290	124370313	X	+	27260156	A673	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.24594783291400368	[378]	[682,485,469,536]	6	hSpCas9	negative selection	5755478
124370263	124370286	X	-	27260156	A673	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.05994165052215883	[756]	[906,855,865,860]	-1	hSpCas9	negative selection	5755479
124365794	124365817	X	-	27260156	A673	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.4284187792400977	[459]	[799,705,618,861]	8	hSpCas9	negative selection	5755480
124346641	124346664	X	-	27260156	A375	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.05865284182156327	[926]	[957,1332,1117,812]	-1	hSpCas9	negative selection	5812475
124365786	124365809	X	+	27260156	A375	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.10572355338154221	[346]	[501,483,328,434]	1	hSpCas9	negative selection	5812476
124346659	124346682	X	+	27260156	A375	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.6913750261439273	[344]	[471,932,635,602]	8	hSpCas9	negative selection	5812477
124370290	124370313	X	+	27260156	A375	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.30054086148705644	[378]	[464,811,289,636]	4	hSpCas9	negative selection	5876729
124370263	124370286	X	-	27260156	A375	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.0722906614856782	[756]	[683,895,723,1038]	-1	hSpCas9	negative selection	5876730
124365794	124365817	X	-	27260156	A375	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.7820901728659617	[459]	[917,1387,872,614]	9	hSpCas9	negative selection	5876731
124346641	124346664	X	-	27260156	COLO741	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.002925883440955901	[926]	[1441,1275,870]	0	hSpCas9	negative selection	5933726
124365786	124365809	X	+	27260156	COLO741	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.1352950576988618	[346]	[585,506,382]	3	hSpCas9	negative selection	5933727
124346659	124346682	X	+	27260156	COLO741	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.14564026344808584	[344]	[550,594,332]	3	hSpCas9	negative selection	5933728
124370290	124370313	X	+	27260156	COLO741	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.019793487508212693	[378]	[280,565,598]	0	hSpCas9	negative selection	5997980
124370263	124370286	X	-	27260156	COLO741	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.24570988780901104	[756]	[995,601,858]	-5	hSpCas9	negative selection	5997981
124365794	124365817	X	-	27260156	COLO741	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.49305055293491656	[459]	[838,887,758]	8	hSpCas9	negative selection	5997982
124346641	124346664	X	-	27260156	CAL120	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.02354880094643874	[926]	[1210,1368,946]	0	hSpCas9	negative selection	6054977
124365786	124365809	X	+	27260156	CAL120	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.4591527556246979	[346]	[753,751,303]	7	hSpCas9	negative selection	6054978
124346659	124346682	X	+	27260156	CAL120	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.3275793801609328	[344]	[542,497,574]	5	hSpCas9	negative selection	6054979
124370290	124370313	X	+	27260156	CAL120	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	-0.1308295199366174	[378]	[555,386,368]	-2	hSpCas9	negative selection	6119231
124370263	124370286	X	-	27260156	CAL120	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.28806412124372416	[756]	[832,638,849]	-4	hSpCas9	negative selection	6119232
124365794	124365817	X	-	27260156	CAL120	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.8536726958385888	[459]	[1433,865,865]	9	hSpCas9	negative selection	6119233
124346641	124346664	X	-	27260156	CADOES1	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.19410357849702453	[926]	[731,671,942,663]	-3	hSpCas9	negative selection	6176228
124365786	124365809	X	+	27260156	CADOES1	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.41022644144310233	[346]	[599,383,352,375]	6	hSpCas9	negative selection	6176229
124346659	124346682	X	+	27260156	CADOES1	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.37280101004696997	[344]	[353,387,351,573]	6	hSpCas9	negative selection	6176230
124370290	124370313	X	+	27260156	CADOES1	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.15931924150927912	[378]	[430,405,433,299]	2	hSpCas9	negative selection	6240482
124370263	124370286	X	-	27260156	CADOES1	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.24015760661557856	[756]	[691,620,479,590]	-4	hSpCas9	negative selection	6240483
124365794	124365817	X	-	27260156	CADOES1	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.7512036930406477	[459]	[578,653,790,861]	9	hSpCas9	negative selection	6240484
124346641	124346664	X	-	27260156	EWS502	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.06753065503868061	[926]	[854,917,956,1031]	-1	hSpCas9	negative selection	6297479
124365786	124365809	X	+	27260156	EWS502	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.12096454817117125	[346]	[297,460,427,421]	2	hSpCas9	negative selection	6297480
124346659	124346682	X	+	27260156	EWS502	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.22633008600879875	[344]	[343,379,511,489]	4	hSpCas9	negative selection	6297481
124370290	124370313	X	+	27260156	EWS502	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.04252834630014174	[378]	[314,377,409,573]	0	hSpCas9	negative selection	6361733
124370263	124370286	X	-	27260156	EWS502	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.1467888392118596	[756]	[535,694,861,834]	-3	hSpCas9	negative selection	6361734
124365794	124365817	X	-	27260156	EWS502	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.7670235724638838	[459]	[585,907,781,1080]	9	hSpCas9	negative selection	6361735
124346641	124346664	X	-	27260156	EW8	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.09009212800143784	[926]	[1129,791,568,780]	1	hSpCas9	negative selection	6418730
124365786	124365809	X	+	27260156	EW8	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.2753862041892734	[346]	[473,285,358,252]	5	hSpCas9	negative selection	6418731
124346659	124346682	X	+	27260156	EW8	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.48266637539708945	[344]	[440,405,368,354]	8	hSpCas9	negative selection	6418732
124370290	124370313	X	+	27260156	EW8	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.5933249371845117	[378]	[337,292,749,407]	9	hSpCas9	negative selection	6482984
124370263	124370286	X	-	27260156	EW8	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.0006861176333518015	[756]	[671,568,592,628]	0	hSpCas9	negative selection	6482985
124365794	124365817	X	-	27260156	EW8	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.6452524543926975	[459]	[430,711,392,809]	9	hSpCas9	negative selection	6482986
124346641	124346664	X	-	27260156	CORL105	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.08683587520910507	[926]	[1212,1173,1328,923]	1	hSpCas9	negative selection	6539981
124365786	124365809	X	+	27260156	CORL105	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	-0.015476944866008868	[346]	[355,398,559,315]	0	hSpCas9	negative selection	6539982
124346659	124346682	X	+	27260156	CORL105	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.31240727273891833	[344]	[646,394,618,370]	6	hSpCas9	negative selection	6539983
124370290	124370313	X	+	27260156	CORL105	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.48310250545292815	[378]	[612,519,896,495]	8	hSpCas9	negative selection	6604235
124370263	124370286	X	-	27260156	CORL105	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.04607437419963234	[756]	[941,618,976,920]	-1	hSpCas9	negative selection	6604236
124365794	124365817	X	-	27260156	CORL105	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.5016226722233676	[459]	[776,729,877,683]	8	hSpCas9	negative selection	6604237
124346641	124346664	X	-	27260156	HS294T	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.2807858485856256	[926]	[235,267,305,391]	-4	hSpCas9	negative selection	6661232
124365786	124365809	X	+	27260156	HS294T	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.2333455665390073	[346]	[81,141,172,257]	3	hSpCas9	negative selection	6661233
124346659	124346682	X	+	27260156	HS294T	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.4256116274994608	[344]	[144,160,164,262]	6	hSpCas9	negative selection	6661234
124370290	124370313	X	+	27260156	HS294T	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	-0.10369890956363254	[378]	[120,106,155,168]	-1	hSpCas9	negative selection	6725486
124370263	124370286	X	-	27260156	HS294T	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.007240361862088873	[756]	[205,373,314,284]	0	hSpCas9	negative selection	6725487
124365794	124365817	X	-	27260156	HS294T	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.35327200434744455	[459]	[187,251,248,220]	5	hSpCas9	negative selection	6725488
124346641	124346664	X	-	27260156	HCC44	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.12355334894182801	[926]	[1063,541,1365,1006]	-2	hSpCas9	negative selection	6782483
124365786	124365809	X	+	27260156	HCC44	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.3236437191677701	[346]	[443,543,423,523]	5	hSpCas9	negative selection	6782484
124346659	124346682	X	+	27260156	HCC44	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.208764388235346	[344]	[522,412,601,304]	3	hSpCas9	negative selection	6782485
124370290	124370313	X	+	27260156	HCC44	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.16376055228711348	[378]	[424,351,616,556]	2	hSpCas9	negative selection	6846737
124370263	124370286	X	-	27260156	HCC44	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.37547310216853796	[756]	[849,363,770,725]	-5	hSpCas9	negative selection	6846738
124365794	124365817	X	-	27260156	HCC44	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.6996892261029907	[459]	[1026,603,1187,669]	9	hSpCas9	negative selection	6846739
124346641	124346664	X	-	27260156	G402	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.14179872011045203	[926]	[1347,1048,998,761]	-2	hSpCas9	negative selection	6903734
124365786	124365809	X	+	27260156	G402	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.36947201204375685	[346]	[440,351,623,732]	4	hSpCas9	negative selection	6903735
124346659	124346682	X	+	27260156	G402	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.3506785482307399	[344]	[675,350,411,706]	4	hSpCas9	negative selection	6903736
124370290	124370313	X	+	27260156	G402	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.05895920839552765	[378]	[703,347,469,429]	0	hSpCas9	negative selection	6967988
124370263	124370286	X	-	27260156	G402	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.44799239818550063	[756]	[1166,299,595,690]	-5	hSpCas9	negative selection	6967989
124365794	124365817	X	-	27260156	G402	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	1.0692965684661122	[459]	[1458,1480,1029,812]	9	hSpCas9	negative selection	6967990
124346641	124346664	X	-	27260156	L33	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.033446044462000946	[926]	[920,378,753,752]	0	hSpCas9	negative selection	7024985
124365786	124365809	X	+	27260156	L33	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.07527952313669645	[346]	[388,133,260,330]	1	hSpCas9	negative selection	7024986
124346659	124346682	X	+	27260156	L33	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.18400016970162375	[344]	[321,172,302,343]	4	hSpCas9	negative selection	7024987
124370290	124370313	X	+	27260156	L33	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	-0.05064083230145089	[378]	[361,106,246,446]	-1	hSpCas9	negative selection	7089239
124370263	124370286	X	-	27260156	L33	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.307666166670671	[756]	[509,253,429,634]	-6	hSpCas9	negative selection	7089240
124365794	124365817	X	-	27260156	L33	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.41250603508454753	[459]	[574,251,435,566]	8	hSpCas9	negative selection	7089241
124346641	124346664	X	-	27260156	K562	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.39449729674457235	[926]	[551,484,812,635]	-5	hSpCas9	negative selection	7146236
124365786	124365809	X	+	27260156	K562	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.9472400333049822	[346]	[692,151,942,571]	9	hSpCas9	negative selection	7146237
124346659	124346682	X	+	27260156	K562	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.5605319407064431	[344]	[284,229,680,568]	7	hSpCas9	negative selection	7146238
124370290	124370313	X	+	27260156	K562	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.44097260257125703	[378]	[492,273,652,403]	5	hSpCas9	negative selection	7210490
124370263	124370286	X	-	27260156	K562	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.14445041977513062	[756]	[865,524,863,713]	1	hSpCas9	negative selection	7210491
124365794	124365817	X	-	27260156	K562	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.6391327480270654	[459]	[783,430,759,573]	7	hSpCas9	negative selection	7210492
124346641	124346664	X	-	27260156	HT29	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.026680465398539854	[926]	[1195,919,1160,1127]	0	hSpCas9	negative selection	7267487
124365786	124365809	X	+	27260156	HT29	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.29832901305605475	[346]	[505,575,527,470]	6	hSpCas9	negative selection	7267488
124346659	124346682	X	+	27260156	HT29	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.3802476925888516	[344]	[654,616,582,361]	7	hSpCas9	negative selection	7267489
124370290	124370313	X	+	27260156	HT29	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	-0.09779864384456272	[378]	[433,453,615,240]	-2	hSpCas9	negative selection	7331741
124370263	124370286	X	-	27260156	HT29	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.04335933261020253	[756]	[954,987,1004,853]	0	hSpCas9	negative selection	7331742
124365794	124365817	X	-	27260156	HT29	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.530182464508721	[459]	[853,764,984,640]	8	hSpCas9	negative selection	7331743
124346641	124346664	X	-	27260156	MHHES1	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.09879007619629043	[926]	[1400,1362,1060,763]	1	hSpCas9	negative selection	7388738
124365786	124365809	X	+	27260156	MHHES1	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.1777144957884207	[346]	[553,401,485,347]	3	hSpCas9	negative selection	7388739
124346659	124346682	X	+	27260156	MHHES1	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.3039155653954115	[344]	[524,524,422,450]	5	hSpCas9	negative selection	7388740
124370290	124370313	X	+	27260156	MHHES1	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.03643608071026794	[378]	[618,426,374,358]	0	hSpCas9	negative selection	7452992
124370263	124370286	X	-	27260156	MHHES1	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.2469405836679962	[756]	[984,1067,1271,761]	4	hSpCas9	negative selection	7452993
124365794	124365817	X	-	27260156	MHHES1	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.5506868572991758	[459]	[995,754,531,760]	8	hSpCas9	negative selection	7452994
124346641	124346664	X	-	27260156	MEWO	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.019641766095667368	[926]	[1053,907,708]	0	hSpCas9	negative selection	7509989
124365786	124365809	X	+	27260156	MEWO	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.28077995887054374	[346]	[426,475,285]	6	hSpCas9	negative selection	7509990
124346659	124346682	X	+	27260156	MEWO	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.5283338190353954	[344]	[432,495,460]	9	hSpCas9	negative selection	7509991
124370290	124370313	X	+	27260156	MEWO	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	-0.16550852385649018	[378]	[400,276,286]	-4	hSpCas9	negative selection	7574243
124370263	124370286	X	-	27260156	MEWO	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.04446760703809227	[756]	[787,612,678]	-1	hSpCas9	negative selection	7574244
124365794	124365817	X	-	27260156	MEWO	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.37618011420185826	[459]	[637,548,503]	7	hSpCas9	negative selection	7574245
124346641	124346664	X	-	27260156	LNCAPCLONEFGC	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.11521111004629747	[926]	[900,996,1017,731]	1	hSpCas9	negative selection	7631240
124365786	124365809	X	+	27260156	LNCAPCLONEFGC	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.13614172522882745	[346]	[264,298,431,402]	2	hSpCas9	negative selection	7631241
124346659	124346682	X	+	27260156	LNCAPCLONEFGC	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.770347442763653	[344]	[544,495,491,594]	9	hSpCas9	negative selection	7631242
124370290	124370313	X	+	27260156	LNCAPCLONEFGC	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.22233009202819598	[378]	[300,275,467,576]	3	hSpCas9	negative selection	7695494
124370263	124370286	X	-	27260156	LNCAPCLONEFGC	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.3135603202371214	[756]	[413,600,698,513]	-5	hSpCas9	negative selection	7695495
124365794	124365817	X	-	27260156	LNCAPCLONEFGC	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.7124625740790577	[459]	[622,477,989,699]	9	hSpCas9	negative selection	7695496
124346641	124346664	X	-	27260156	PANC0327	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.029070915927527197	[926]	[799,833,791,931]	0	hSpCas9	negative selection	7752491
124365786	124365809	X	+	27260156	PANC0327	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.4162470145252672	[346]	[560,238,538,340]	6	hSpCas9	negative selection	7752492
124346659	124346682	X	+	27260156	PANC0327	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	-0.012541977198574805	[344]	[192,364,237,401]	0	hSpCas9	negative selection	7752493
124370290	124370313	X	+	27260156	PANC0327	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.27399844014627556	[378]	[368,384,447,425]	4	hSpCas9	negative selection	7816745
124370263	124370286	X	-	27260156	PANC0327	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.18176144258920202	[756]	[603,740,1017,677]	2	hSpCas9	negative selection	7816746
124365794	124365817	X	-	27260156	PANC0327	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.23561352546226247	[459]	[568,483,395,481]	3	hSpCas9	negative selection	7816747
124346641	124346664	X	-	27260156	NCIH2009	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.099126573030628	[926]	[1764,1615,848]	1	hSpCas9	negative selection	7873742
124365786	124365809	X	+	27260156	NCIH2009	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.491987124091031	[346]	[528,688,795]	6	hSpCas9	negative selection	7873743
124346659	124346682	X	+	27260156	NCIH2009	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.41746132426910787	[344]	[644,338,951]	6	hSpCas9	negative selection	7873744
124370290	124370313	X	+	27260156	NCIH2009	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.2195349831359133	[378]	[881,565,453]	3	hSpCas9	negative selection	7937996
124370263	124370286	X	-	27260156	NCIH2009	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.31873616035813396	[756]	[834,680,1026]	-4	hSpCas9	negative selection	7937997
124365794	124365817	X	-	27260156	NCIH2009	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.6593504103099871	[459]	[1152,942,975]	8	hSpCas9	negative selection	7937998
124346641	124346664	X	-	27260156	NCIH1373	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.1073422391584542	[926]	[743,839,1057,315]	-1	hSpCas9	negative selection	7994993
124365786	124365809	X	+	27260156	NCIH1373	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.6593970087313844	[346]	[585,662,792,100]	6	hSpCas9	negative selection	7994994
124346659	124346682	X	+	27260156	NCIH1373	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.6427719395139316	[344]	[840,772,502,77]	6	hSpCas9	negative selection	7994995
124370290	124370313	X	+	27260156	NCIH1373	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	-0.06324083001276665	[378]	[382,318,346,155]	0	hSpCas9	negative selection	8059247
124370263	124370286	X	-	27260156	NCIH1373	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.5351249939496651	[756]	[667,386,662,172]	-5	hSpCas9	negative selection	8059248
124365794	124365817	X	-	27260156	NCIH1373	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	1.1392608083353961	[459]	[1699,736,663,421]	9	hSpCas9	negative selection	8059249
124346641	124346664	X	-	27260156	PATU8902	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.07318341566183872	[926]	[940,1287,1216,1490]	0	hSpCas9	negative selection	8116244
124365786	124365809	X	+	27260156	PATU8902	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.47149150958331376	[346]	[489,861,597,756]	5	hSpCas9	negative selection	8116245
124346659	124346682	X	+	27260156	PATU8902	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.4655008179029204	[344]	[327,772,625,972]	5	hSpCas9	negative selection	8116246
124370290	124370313	X	+	27260156	PATU8902	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.5196959973343929	[378]	[1048,1045,444,531]	5	hSpCas9	negative selection	8180498
124370263	124370286	X	-	27260156	PATU8902	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.018876528098819567	[756]	[843,1208,949,1325]	0	hSpCas9	negative selection	8180499
124365794	124365817	X	-	27260156	PATU8902	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	1.1457818118759242	[459]	[994,1712,1903,859]	9	hSpCas9	negative selection	8180500
124346641	124346664	X	-	27260156	PANC1	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.14078339885568358	[926]	[783,1059,975,739]	2	hSpCas9	negative selection	8237495
124365786	124365809	X	+	27260156	PANC1	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.5798490403086596	[346]	[371,518,426,468]	8	hSpCas9	negative selection	8237496
124346659	124346682	X	+	27260156	PANC1	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.5611752715964008	[344]	[297,817,443,287]	8	hSpCas9	negative selection	8237497
124370290	124370313	X	+	27260156	PANC1	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.6444498420858799	[378]	[693,619,311,430]	9	hSpCas9	negative selection	8301749
124370263	124370286	X	-	27260156	PANC1	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.4501486123131523	[756]	[874,764,992,881]	7	hSpCas9	negative selection	8301750
124365794	124365817	X	-	27260156	PANC1	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.5711674333437726	[459]	[645,682,476,554]	8	hSpCas9	negative selection	8301751
124346641	124346664	X	-	27260156	PANC0813	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.013832808796399587	[926]	[1322,1117,993,908]	0	hSpCas9	negative selection	8358746
124365786	124365809	X	+	27260156	PANC0813	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.4986426656597146	[346]	[857,451,422,593]	7	hSpCas9	negative selection	8358747
124346659	124346682	X	+	27260156	PANC0813	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.35448701423148854	[344]	[589,467,497,521]	6	hSpCas9	negative selection	8358748
124370290	124370313	X	+	27260156	PANC0813	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.3527960527828185	[378]	[737,614,506,435]	5	hSpCas9	negative selection	8423000
124370263	124370286	X	-	27260156	PANC0813	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.13077687085292722	[756]	[1014,618,748,878]	-2	hSpCas9	negative selection	8423001
124365794	124365817	X	-	27260156	PANC0813	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.6671778587145056	[459]	[1029,864,661,886]	9	hSpCas9	negative selection	8423002
124346641	124346664	X	-	27260156	RDES	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.07691003584160727	[926]	[770,956,1137,1244]	-1	hSpCas9	negative selection	8479997
124365786	124365809	X	+	27260156	RDES	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.32981704283237784	[346]	[434,547,458,565]	5	hSpCas9	negative selection	8479998
124346659	124346682	X	+	27260156	RDES	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.5815576330090162	[344]	[526,530,690,637]	8	hSpCas9	negative selection	8479999
124370290	124370313	X	+	27260156	RDES	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.16311607328205135	[378]	[338,405,603,660]	2	hSpCas9	negative selection	8544251
124370263	124370286	X	-	27260156	RDES	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.01224056102270299	[756]	[739,748,1028,1039]	0	hSpCas9	negative selection	8544252
124365794	124365817	X	-	27260156	RDES	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.6779365450026623	[459]	[825,746,837,979]	9	hSpCas9	negative selection	8544253
124346641	124346664	X	-	27260156	PC3	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.19672330188812703	[926]	[668,1001,1496,1319]	4	hSpCas9	negative selection	8601248
124365786	124365809	X	+	27260156	PC3	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	-0.10461240916747622	[346]	[196,382,362,381]	-2	hSpCas9	negative selection	8601249
124346659	124346682	X	+	27260156	PC3	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.45752582062802505	[344]	[361,412,662,523]	8	hSpCas9	negative selection	8601250
124370290	124370313	X	+	27260156	PC3	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	-0.11164565789300873	[378]	[200,329,711,330]	-3	hSpCas9	negative selection	8665502
124370263	124370286	X	-	27260156	PC3	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.419819305442818	[756]	[384,476,859,678]	-7	hSpCas9	negative selection	8665503
124365794	124365817	X	-	27260156	PC3	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.565404720893116	[459]	[598,578,1110,537]	9	hSpCas9	negative selection	8665504
124346641	124346664	X	-	27260156	PATU8988T	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.04490311822057891	[926]	[816,661,1283,668]	-1	hSpCas9	negative selection	8722499
124365786	124365809	X	+	27260156	PATU8988T	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.25189528326142385	[346]	[477,527,291,304]	4	hSpCas9	negative selection	8722500
124346659	124346682	X	+	27260156	PATU8988T	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.3841305544652094	[344]	[496,398,437,399]	6	hSpCas9	negative selection	8722501
124370290	124370313	X	+	27260156	PATU8988T	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	-0.22140901270317337	[378]	[323,343,235,359]	-4	hSpCas9	negative selection	8786753
124370263	124370286	X	-	27260156	PATU8988T	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.5681782765803751	[756]	[527,355,486,597]	-7	hSpCas9	negative selection	8786754
124365794	124365817	X	-	27260156	PATU8988T	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.16732800584562985	[459]	[416,585,449,556]	3	hSpCas9	negative selection	8786755
124346641	124346664	X	-	27260156	T47D	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.03212597484640611	[926]	[1095,976,1032,1127]	0	hSpCas9	negative selection	8843750
124365786	124365809	X	+	27260156	T47D	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.30541183359533075	[346]	[425,462,573,537]	6	hSpCas9	negative selection	8843751
124346659	124346682	X	+	27260156	T47D	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.4046352103972303	[344]	[459,500,508,664]	8	hSpCas9	negative selection	8843752
124370290	124370313	X	+	27260156	T47D	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.1490863452588986	[378]	[505,425,419,616]	3	hSpCas9	negative selection	8908004
124370263	124370286	X	-	27260156	T47D	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.09091678609337073	[756]	[1027,884,874,975]	2	hSpCas9	negative selection	8908005
124365794	124365817	X	-	27260156	T47D	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.46814726175728777	[459]	[938,593,750,692]	8	hSpCas9	negative selection	8908006
124346641	124346664	X	-	27260156	SU8686	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.023185736182801953	[926]	[961,750,797,1292]	0	hSpCas9	negative selection	8965001
124365786	124365809	X	+	27260156	SU8686	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.40955195647738496	[346]	[358,389,441,690]	7	hSpCas9	negative selection	8965002
124346659	124346682	X	+	27260156	SU8686	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.3222211942420659	[344]	[402,437,310,577]	5	hSpCas9	negative selection	8965003
124370290	124370313	X	+	27260156	SU8686	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	-0.10676844989043688	[378]	[237,304,334,568]	-2	hSpCas9	negative selection	9029255
124370263	124370286	X	-	27260156	SU8686	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.32976407367254684	[756]	[445,651,578,739]	-5	hSpCas9	negative selection	9029256
124365794	124365817	X	-	27260156	SU8686	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.7425135914559696	[459]	[566,634,973,944]	9	hSpCas9	negative selection	9029257
124346641	124346664	X	-	27260156	SKES1	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	0.15554253081997593	[926]	[1278,1076,821,979]	3	hSpCas9	negative selection	9086252
124365786	124365809	X	+	27260156	SKES1	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.05206300066766306	[346]	[394,431,356,271]	1	hSpCas9	negative selection	9086253
124346659	124346682	X	+	27260156	SKES1	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.4074479951137317	[344]	[441,623,401,380]	8	hSpCas9	negative selection	9086254
124370290	124370313	X	+	27260156	SKES1	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.3124289090500227	[378]	[585,387,511,400]	6	hSpCas9	negative selection	9150506
124370263	124370286	X	-	27260156	SKES1	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.20004834417211392	[756]	[811,698,677,480]	-4	hSpCas9	negative selection	9150507
124365794	124365817	X	-	27260156	SKES1	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.5865516920493471	[459]	[749,937,621,500]	9	hSpCas9	negative selection	9150508
124346641	124346664	X	-	27260156	TOV112D	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.007894790176784405	[926]	[890,1182,968,715]	0	hSpCas9	negative selection	9207503
124365786	124365809	X	+	27260156	TOV112D	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.21368631370973376	[346]	[397,497,321,415]	4	hSpCas9	negative selection	9207504
124346659	124346682	X	+	27260156	TOV112D	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.5915136040531936	[344]	[650,530,417,495]	9	hSpCas9	negative selection	9207505
124370290	124370313	X	+	27260156	TOV112D	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.4200526898076538	[378]	[526,516,535,455]	7	hSpCas9	negative selection	9271757
124370263	124370286	X	-	27260156	TOV112D	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.28963469590228214	[756]	[504,994,421,639]	-5	hSpCas9	negative selection	9271758
124365794	124365817	X	-	27260156	TOV112D	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.7335779716567791	[459]	[683,1243,636,612]	9	hSpCas9	negative selection	9271759
124346641	124346664	X	-	27260156	TC71	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.03653718127753591	[926]	[832,880,1059,1109]	-1	hSpCas9	negative selection	9328754
124365786	124365809	X	+	27260156	TC71	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.06159010930497405	[346]	[318,457,281,505]	1	hSpCas9	negative selection	9328755
124346659	124346682	X	+	27260156	TC71	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.3463008988145824	[344]	[439,455,461,526]	7	hSpCas9	negative selection	9328756
124370290	124370313	X	+	27260156	TC71	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.16503162858971696	[378]	[323,553,467,479]	4	hSpCas9	negative selection	9393008
124370263	124370286	X	-	27260156	TC71	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	0.16225811208008822	[756]	[936,944,769,988]	4	hSpCas9	negative selection	9393009
124365794	124365817	X	-	27260156	TC71	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.4797883779963235	[459]	[574,702,702,776]	9	hSpCas9	negative selection	9393010
124346641	124346664	X	-	27260156	TC32	viability	ATACACAGCCACTGCGTCCATGG	SH2D1A	ENSG00000183918	-0.2964377967810208	[926]	[684,342,1031,950]	-5	hSpCas9	negative selection	9450005
124365786	124365809	X	+	27260156	TC32	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.3130456967880508	[346]	[471,300,513,354]	5	hSpCas9	negative selection	9450006
124346659	124346682	X	+	27260156	TC32	viability	TGTATCATGGCAAAATCAGCAGG	SH2D1A	ENSG00000183918	0.22052121362577193	[344]	[297,266,474,526]	4	hSpCas9	negative selection	9450007
124370290	124370313	X	+	27260156	TC32	viability	TCCTCAGCTAGAAGTACACAAGG	SH2D1A	ENSG00000183918	0.18863926684146243	[378]	[335,315,411,589]	3	hSpCas9	negative selection	9514259
124370263	124370286	X	-	27260156	TC32	viability	TTCTCAACTGGATACTGCAGAGG	SH2D1A	ENSG00000183918	-0.24867379382034005	[756]	[441,542,731,711]	-4	hSpCas9	negative selection	9514260
124365794	124365817	X	-	27260156	TC32	viability	TCCAAGAACCTGTTTCTGTCTGG	SH2D1A	ENSG00000183918	0.8751904508904346	[459]	[610,725,873,984]	9	hSpCas9	negative selection	9514261
124346691	124346714	X	+	27869803	HPAFII	viability after 27 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	-0.25551993581434207	[44]	[3,32,NaN]	-2	hSpCas9	negative selection	9607435
124346707	124346730	X	-	27869803	HPAFII	viability after 27 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.9268221389622451	[172]	[173,171,NaN]	7	hSpCas9	negative selection	9607436
124365786	124365809	X	+	27869803	HPAFII	viability after 27 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.5723788110126147	[628]	[434,538,NaN]	4	hSpCas9	negative selection	9607437
124346691	124346714	X	+	27869803	HPAFII	viability after 15 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	-0.7140486340313945	[44]	[18,35,NaN]	-6	hSpCas9	negative selection	9689884
124346707	124346730	X	-	27869803	HPAFII	viability after 15 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	1.095188605870979	[172]	[596,272,NaN]	9	hSpCas9	negative selection	9689885
124365786	124365809	X	+	27869803	HPAFII	viability after 15 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.28976153759663204	[628]	[908,774,NaN]	3	hSpCas9	negative selection	9689886
124346691	124346714	X	+	27869803	ASPC1	viability after 36 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	-0.9832970098964977	[122]	[53,18,0]	-7	hSpCas9	negative selection	9772333
124346707	124346730	X	-	27869803	ASPC1	viability after 36 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.6821812575706373	[380]	[419,59,187]	6	hSpCas9	negative selection	9772334
124365786	124365809	X	+	27869803	ASPC1	viability after 36 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.04094228160473268	[1479]	[1051,277,361]	0	hSpCas9	negative selection	9772335
124346691	124346714	X	+	27869803	PATU8988S	viability after 35 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.7349798827166774	[105]	[94,46,NaN]	7	hSpCas9	negative selection	9854782
124346707	124346730	X	-	27869803	PATU8988S	viability after 35 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.7064913524290738	[330]	[234,199,NaN]	7	hSpCas9	negative selection	9854783
124365786	124365809	X	+	27869803	PATU8988S	viability after 35 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.41068771645134583	[1226]	[619,693,NaN]	4	hSpCas9	negative selection	9854784
124346691	124346714	X	+	27869803	PATU8988S	viability after 31 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.9832888901990784	[105]	[83,82,NaN]	9	hSpCas9	negative selection	9937231
124346707	124346730	X	-	27869803	PATU8988S	viability after 31 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.5937682208516202	[330]	[141,271,NaN]	7	hSpCas9	negative selection	9937232
124365786	124365809	X	+	27869803	PATU8988S	viability after 31 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.2532139323970293	[1226]	[616,539,NaN]	3	hSpCas9	negative selection	9937233
124346691	124346714	X	+	27869803	HPAFII	viability after 35 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	-1.5866191218319297	[44]	[0,14,NaN]	-7	hSpCas9	negative selection	10019680
124346707	124346730	X	-	27869803	HPAFII	viability after 35 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	0.9754149036900193	[172]	[103,248,NaN]	6	hSpCas9	negative selection	10019681
124365786	124365809	X	+	27869803	HPAFII	viability after 35 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.9264160253619549	[628]	[512,708,NaN]	6	hSpCas9	negative selection	10019682
124346691	124346714	X	+	27869803	HPAFII	viability after 31 days	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	-0.47035229983451377	[44]	[0,36,NaN]	-3	hSpCas9	negative selection	10102129
124346707	124346730	X	-	27869803	HPAFII	viability after 31 days	ATAGCTGCCATCCAGCCCAGTGG	SH2D1A	ENSG00000183918	1.1639461786917003	[172]	[173,264,NaN]	8	hSpCas9	negative selection	10102130
124365786	124365809	X	+	27869803	HPAFII	viability after 31 days	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.5557677184473551	[628]	[538,496,NaN]	4	hSpCas9	negative selection	10102131
124346633	124346656	X	+	28162770	P31FUJ	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.420640034189544	[191]	[301]	5	hSpCas9	negative selection	10233415
124370165	124370188	X	+	28162770	P31FUJ	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.45864873049945887	[482]	[779]	5	hSpCas9	negative selection	10233416
124346691	124346714	X	+	28162770	P31FUJ	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.4283958821338628	[171]	[271]	5	hSpCas9	negative selection	10233417
124346717	124346740	X	+	28162770	P31FUJ	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	1.303250695825831	[99]	[289]	9	hSpCas9	negative selection	10233418
124346660	124346683	X	+	28162770	P31FUJ	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.22131281684715592	[172]	[236]	2	hSpCas9	negative selection	10233419
124365803	124365826	X	+	28162770	P31FUJ	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	0.546170916273403	[87]	[150]	6	hSpCas9	negative selection	10233420
124370230	124370253	X	+	28162770	P31FUJ	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	0.6281641019476172	[282]	[513]	7	hSpCas9	negative selection	10233421
124346768	124346791	X	-	28162770	P31FUJ	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.618553714230486	[285]	[515]	7	hSpCas9	negative selection	10233422
124365786	124365809	X	+	28162770	P31FUJ	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.6626836279218906	[507]	[944]	7	hSpCas9	negative selection	10233423
124370291	124370314	X	-	28162770	P31FUJ	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	0.2847323687864869	[291]	[417]	3	hSpCas9	negative selection	10233424
124346633	124346656	X	+	28162770	TF1	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	NaN	[NaN]	[169]	1	hSpCas9	negative selection	10402781
124370165	124370188	X	+	28162770	TF1	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	NaN	[NaN]	[402]	1	hSpCas9	negative selection	10402782
124346691	124346714	X	+	28162770	TF1	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	NaN	[NaN]	[418]	1	hSpCas9	negative selection	10402783
124346717	124346740	X	+	28162770	TF1	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	NaN	[NaN]	[192]	1	hSpCas9	negative selection	10402784
124346660	124346683	X	+	28162770	TF1	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	NaN	[NaN]	[338]	1	hSpCas9	negative selection	10402785
124365803	124365826	X	+	28162770	TF1	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10402786
124370230	124370253	X	+	28162770	TF1	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	NaN	[NaN]	[377]	1	hSpCas9	negative selection	10402787
124346768	124346791	X	-	28162770	TF1	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	NaN	[NaN]	[585]	1	hSpCas9	negative selection	10402788
124365786	124365809	X	+	28162770	TF1	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	NaN	[NaN]	[693]	1	hSpCas9	negative selection	10402789
124370291	124370314	X	-	28162770	TF1	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	NaN	[NaN]	[383]	1	hSpCas9	negative selection	10402790
124346633	124346656	X	+	28162770	SKM1	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.4367325703781629	[55]	[133]	4	hSpCas9	negative selection	10572147
124370165	124370188	X	+	28162770	SKM1	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.1550371535346834	[94]	[186]	1	hSpCas9	negative selection	10572148
124346691	124346714	X	+	28162770	SKM1	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	1.0908876382079562	[63]	[240]	8	hSpCas9	negative selection	10572149
124346717	124346740	X	+	28162770	SKM1	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	-0.41391695938492856	[51]	[68]	-3	hSpCas9	negative selection	10572150
124346660	124346683	X	+	28162770	SKM1	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.4813904454279292	[46]	[115]	5	hSpCas9	negative selection	10572151
124365803	124365826	X	+	28162770	SKM1	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	1.1039977205342175	[19]	[75]	8	hSpCas9	negative selection	10572152
124370230	124370253	X	+	28162770	SKM1	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	0.7781472065138267	[62]	[190]	7	hSpCas9	negative selection	10572153
124346768	124346791	X	-	28162770	SKM1	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	-0.18217726226633107	[85]	[133]	-1	hSpCas9	negative selection	10572154
124365786	124365809	X	+	28162770	SKM1	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.3211929378057852	[114]	[253]	3	hSpCas9	negative selection	10572155
124370291	124370314	X	-	28162770	SKM1	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	0.41321476367202614	[47]	[112]	4	hSpCas9	negative selection	10572156
124346633	124346656	X	+	28162770	SKM1	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.4367325703781629	[55]	[133]	4	hSpCas9	negative selection	10741513
124370165	124370188	X	+	28162770	SKM1	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.1550371535346834	[94]	[186]	1	hSpCas9	negative selection	10741514
124346691	124346714	X	+	28162770	SKM1	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	1.0908876382079562	[63]	[240]	8	hSpCas9	negative selection	10741515
124346717	124346740	X	+	28162770	SKM1	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	-0.41391695938492856	[51]	[68]	-3	hSpCas9	negative selection	10741516
124346660	124346683	X	+	28162770	SKM1	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.4813904454279292	[46]	[115]	5	hSpCas9	negative selection	10741517
124365803	124365826	X	+	28162770	SKM1	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	1.1039977205342175	[19]	[75]	8	hSpCas9	negative selection	10741518
124370230	124370253	X	+	28162770	SKM1	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	0.7781472065138267	[62]	[190]	7	hSpCas9	negative selection	10741519
124346768	124346791	X	-	28162770	SKM1	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	-0.18217726226633107	[85]	[133]	-1	hSpCas9	negative selection	10741520
124365786	124365809	X	+	28162770	SKM1	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.3211929378057852	[114]	[253]	3	hSpCas9	negative selection	10741521
124370291	124370314	X	-	28162770	SKM1	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	0.41321476367202614	[47]	[112]	4	hSpCas9	negative selection	10741522
124346633	124346656	X	+	28162770	PL21	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.4461580433075123	[198]	[117]	4	hSpCas9	negative selection	10910879
124370165	124370188	X	+	28162770	PL21	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	-0.03159067142646399	[309]	[131]	0	hSpCas9	negative selection	10910880
124346691	124346714	X	+	28162770	PL21	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.5574007824889633	[241]	[154]	5	hSpCas9	negative selection	10910881
124346717	124346740	X	+	28162770	PL21	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.20013961448932016	[133]	[66]	1	hSpCas9	negative selection	10910882
124346660	124346683	X	+	28162770	PL21	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.1739080729161405	[221]	[108]	1	hSpCas9	negative selection	10910883
124365803	124365826	X	+	28162770	PL21	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	-2.1086130916503087	[108]	[10]	-8	hSpCas9	negative selection	10910884
124370230	124370253	X	+	28162770	PL21	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	0.5947130112084484	[212]	[139]	5	hSpCas9	negative selection	10910885
124346768	124346791	X	-	28162770	PL21	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	-0.10419442038330395	[325]	[131]	0	hSpCas9	negative selection	10910886
124365786	124365809	X	+	28162770	PL21	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.771296315685446	[349]	[259]	6	hSpCas9	negative selection	10910887
124370291	124370314	X	-	28162770	PL21	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	1.2160811583583415	[179]	[181]	8	hSpCas9	negative selection	10910888
124346633	124346656	X	+	28162770	P31FUJ	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.420640034189544	[191]	[301]	5	hSpCas9	negative selection	11080245
124370165	124370188	X	+	28162770	P31FUJ	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.45864873049945887	[482]	[779]	5	hSpCas9	negative selection	11080246
124346691	124346714	X	+	28162770	P31FUJ	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.4283958821338628	[171]	[271]	5	hSpCas9	negative selection	11080247
124346717	124346740	X	+	28162770	P31FUJ	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	1.303250695825831	[99]	[289]	9	hSpCas9	negative selection	11080248
124346660	124346683	X	+	28162770	P31FUJ	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.22131281684715592	[172]	[236]	2	hSpCas9	negative selection	11080249
124365803	124365826	X	+	28162770	P31FUJ	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	0.546170916273403	[87]	[150]	6	hSpCas9	negative selection	11080250
124370230	124370253	X	+	28162770	P31FUJ	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	0.6281641019476172	[282]	[513]	7	hSpCas9	negative selection	11080251
124346768	124346791	X	-	28162770	P31FUJ	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.618553714230486	[285]	[515]	7	hSpCas9	negative selection	11080252
124365786	124365809	X	+	28162770	P31FUJ	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.6626836279218906	[507]	[944]	7	hSpCas9	negative selection	11080253
124370291	124370314	X	-	28162770	P31FUJ	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	0.2847323687864869	[291]	[417]	3	hSpCas9	negative selection	11080254
124346633	124346656	X	+	28162770	OCIAML5	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	1.5629709284148467	[86]	[463]	9	hSpCas9	negative selection	11249611
124370165	124370188	X	+	28162770	OCIAML5	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.29579953165061523	[226]	[502]	2	hSpCas9	negative selection	11249612
124346691	124346714	X	+	28162770	OCIAML5	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.4320768615638951	[146]	[357]	4	hSpCas9	negative selection	11249613
124346717	124346740	X	+	28162770	OCIAML5	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.8957464055392015	[105]	[355]	7	hSpCas9	negative selection	11249614
124346660	124346683	X	+	28162770	OCIAML5	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.6950938971447748	[115]	[338]	6	hSpCas9	negative selection	11249615
124365803	124365826	X	+	28162770	OCIAML5	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	0.9093224972414267	[40]	[138]	7	hSpCas9	negative selection	11249616
124370230	124370253	X	+	28162770	OCIAML5	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	1.3002395779420854	[118]	[528]	9	hSpCas9	negative selection	11249617
124346768	124346791	X	-	28162770	OCIAML5	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.24953156914380992	[232]	[499]	2	hSpCas9	negative selection	11249618
124365786	124365809	X	+	28162770	OCIAML5	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.9121204920372337	[314]	[1069]	7	hSpCas9	negative selection	11249619
124370291	124370314	X	-	28162770	OCIAML5	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	1.0328949208697864	[136]	[505]	8	hSpCas9	negative selection	11249620
124346633	124346656	X	+	28162770	EOL1	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.5715712404239424	[363]	[284]	5	hSpCas9	negative selection	11418977
124370165	124370188	X	+	28162770	EOL1	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.604369458633132	[411]	[329]	5	hSpCas9	negative selection	11418978
124346691	124346714	X	+	28162770	EOL1	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.8928389118431963	[413]	[404]	7	hSpCas9	negative selection	11418979
124346717	124346740	X	+	28162770	EOL1	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.18606434976207503	[316]	[189]	1	hSpCas9	negative selection	11418980
124346660	124346683	X	+	28162770	EOL1	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.1505514464593613	[341]	[199]	1	hSpCas9	negative selection	11418981
124365803	124365826	X	+	28162770	EOL1	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	1.3823983543883513	[165]	[227]	9	hSpCas9	negative selection	11418982
124370230	124370253	X	+	28162770	EOL1	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	0.5443641044276294	[258]	[198]	5	hSpCas9	negative selection	11418983
124346768	124346791	X	-	28162770	EOL1	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.23848307570436622	[361]	[224]	2	hSpCas9	negative selection	11418984
124365786	124365809	X	+	28162770	EOL1	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.28641461182804073	[455]	[292]	2	hSpCas9	negative selection	11418985
124370291	124370314	X	-	28162770	EOL1	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	0.26201671735367493	[276]	[174]	2	hSpCas9	negative selection	11418986
124346633	124346656	X	+	28162770	MOLM13	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	1.2700265943311635	[276]	[482]	8	hSpCas9	negative selection	11588343
124370165	124370188	X	+	28162770	MOLM13	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.395889657682044	[492]	[468]	3	hSpCas9	negative selection	11588344
124346691	124346714	X	+	28162770	MOLM13	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.7664502210075139	[360]	[443]	6	hSpCas9	negative selection	11588345
124346717	124346740	X	+	28162770	MOLM13	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.5999177752283626	[239]	[262]	4	hSpCas9	negative selection	11588346
124346660	124346683	X	+	28162770	MOLM13	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	1.1850267664119087	[336]	[553]	8	hSpCas9	negative selection	11588347
124365803	124365826	X	+	28162770	MOLM13	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	1.4943615929057696	[107]	[219]	9	hSpCas9	negative selection	11588348
124370230	124370253	X	+	28162770	MOLM13	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	0.6494961880345265	[327]	[371]	5	hSpCas9	negative selection	11588349
124346768	124346791	X	-	28162770	MOLM13	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	-1.5589106777991364	[814]	[199]	-6	hSpCas9	negative selection	11588350
124365786	124365809	X	+	28162770	MOLM13	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.767274907780853	[515]	[634]	6	hSpCas9	negative selection	11588351
124370291	124370314	X	-	28162770	MOLM13	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	0.3126111560666678	[244]	[219]	2	hSpCas9	negative selection	11588352
124346633	124346656	X	+	28162770	HEL	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	1.5870293994140694	[263]	[507]	9	hSpCas9	negative selection	11757709
124370165	124370188	X	+	28162770	HEL	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.25232511969033555	[425]	[324]	2	hSpCas9	negative selection	11757710
124346691	124346714	X	+	28162770	HEL	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	1.0870918981037565	[340]	[463]	8	hSpCas9	negative selection	11757711
124346717	124346740	X	+	28162770	HEL	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	0.4915747586667061	[190]	[171]	4	hSpCas9	negative selection	11757712
124346660	124346683	X	+	28162770	HEL	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.8412845113824374	[304]	[349]	7	hSpCas9	negative selection	11757713
124365803	124365826	X	+	28162770	HEL	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	0.3066896288683419	[153]	[121]	2	hSpCas9	negative selection	11757714
124370230	124370253	X	+	28162770	HEL	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	0.19135948565779268	[200]	[146]	1	hSpCas9	negative selection	11757715
124346768	124346791	X	-	28162770	HEL	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.3194308278342983	[522]	[417]	2	hSpCas9	negative selection	11757716
124365786	124365809	X	+	28162770	HEL	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.701072142316684	[411]	[428]	6	hSpCas9	negative selection	11757717
124370291	124370314	X	-	28162770	HEL	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	1.0358109997824092	[181]	[238]	8	hSpCas9	negative selection	11757718
124346633	124346656	X	+	28162770	MV411	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.4867284966925917	[193]	[228]	4	hSpCas9	negative selection	11927075
124370165	124370188	X	+	28162770	MV411	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.6213451741017645	[337]	[437]	5	hSpCas9	negative selection	11927076
124346691	124346714	X	+	28162770	MV411	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.552292132311196	[254]	[314]	5	hSpCas9	negative selection	11927077
124346717	124346740	X	+	28162770	MV411	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	-0.5155232519163755	[111]	[65]	-4	hSpCas9	negative selection	11927078
124346660	124346683	X	+	28162770	MV411	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	1.3916086544694093	[156]	[346]	9	hSpCas9	negative selection	11927079
124365803	124365826	X	+	28162770	MV411	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	-0.7525624492172249	[153]	[76]	-5	hSpCas9	negative selection	11927080
124370230	124370253	X	+	28162770	MV411	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	0.4459832301648555	[121]	[139]	4	hSpCas9	negative selection	11927081
124346768	124346791	X	-	28162770	MV411	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.4188059690947563	[221]	[249]	4	hSpCas9	negative selection	11927082
124365786	124365809	X	+	28162770	MV411	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	1.0628954532682808	[278]	[490]	8	hSpCas9	negative selection	11927083
124370291	124370314	X	-	28162770	MV411	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	1.1993432625817304	[182]	[353]	9	hSpCas9	negative selection	11927084
124346633	124346656	X	+	28162770	MONOMAC1	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.31649051561865327	[137]	[196]	3	hSpCas9	negative selection	12096441
124370165	124370188	X	+	28162770	MONOMAC1	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.4948408575781146	[233]	[377]	5	hSpCas9	negative selection	12096442
124346691	124346714	X	+	28162770	MONOMAC1	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.8029631529404463	[134]	[269]	7	hSpCas9	negative selection	12096443
124346717	124346740	X	+	28162770	MONOMAC1	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	-0.14100281214522586	[100]	[104]	-1	hSpCas9	negative selection	12096444
124346660	124346683	X	+	28162770	MONOMAC1	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.7289625714966694	[109]	[208]	7	hSpCas9	negative selection	12096445
124365803	124365826	X	+	28162770	MONOMAC1	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	-0.09320103607501373	[66]	[71]	-1	hSpCas9	negative selection	12096446
124370230	124370253	X	+	28162770	MONOMAC1	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	2.8358064096274633	[113]	[932]	9	hSpCas9	negative selection	12096447
124346768	124346791	X	-	28162770	MONOMAC1	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	0.12670481819973967	[158]	[198]	1	hSpCas9	negative selection	12096448
124365786	124365809	X	+	28162770	MONOMAC1	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.39199531797064957	[235]	[354]	4	hSpCas9	negative selection	12096449
124370291	124370314	X	-	28162770	MONOMAC1	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	0.8242317696940976	[100]	[204]	7	hSpCas9	negative selection	12096450
124346633	124346656	X	+	28162770	OCIAML2	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.5693858536057179	[39]	[328]	5	hSpCas9	negative selection	12265807
124370165	124370188	X	+	28162770	OCIAML2	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.3915609628955432	[58]	[428]	4	hSpCas9	negative selection	12265808
124346691	124346714	X	+	28162770	OCIAML2	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.6503855757192049	[39]	[347]	6	hSpCas9	negative selection	12265809
124346717	124346740	X	+	28162770	OCIAML2	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	1.0548316637303332	[32]	[379]	8	hSpCas9	negative selection	12265810
124346660	124346683	X	+	28162770	OCIAML2	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.8738996985823339	[37]	[385]	8	hSpCas9	negative selection	12265811
124365803	124365826	X	+	28162770	OCIAML2	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	-0.12893847553336907	[28]	[146]	-1	hSpCas9	negative selection	12265812
124370230	124370253	X	+	28162770	OCIAML2	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	-0.27661920527553574	[32]	[150]	-2	hSpCas9	negative selection	12265813
124346768	124346791	X	-	28162770	OCIAML2	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	-0.061517159920422726	[60]	[323]	0	hSpCas9	negative selection	12265814
124365786	124365809	X	+	28162770	OCIAML2	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.7591045714354546	[62]	[590]	7	hSpCas9	negative selection	12265815
124370291	124370314	X	-	28162770	OCIAML2	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	1.085573682497571	[37]	[446]	9	hSpCas9	negative selection	12265816
124346633	124346656	X	+	28162770	OCIAML3	viability	CCACCAGGCCATGGACGCAGTGG	SH2D1A	ENSG00000183918	0.6412088213698683	[47]	[225]	6	hSpCas9	negative selection	12435173
124370165	124370188	X	+	28162770	OCIAML3	viability	TTATTTTCCAGACAGCACCTGGG	SH2D1A	ENSG00000183918	0.26463651043029546	[74]	[271]	2	hSpCas9	negative selection	12435174
124346691	124346714	X	+	28162770	OCIAML3	viability	GAGAAGCTCCTGCTTGCCACTGG	SH2D1A	ENSG00000183918	0.5859014496907713	[63]	[289]	5	hSpCas9	negative selection	12435175
124346717	124346740	X	+	28162770	OCIAML3	viability	GGATGGCAGCTATTTGCTGAGGG	SH2D1A	ENSG00000183918	2.7534555466703368	[27]	[569]	9	hSpCas9	negative selection	12435176
124346660	124346683	X	+	28162770	OCIAML3	viability	GTATCATGGCAAAATCAGCAGGG	SH2D1A	ENSG00000183918	0.15194673706929773	[47]	[160]	1	hSpCas9	negative selection	12435177
124365803	124365826	X	+	28162770	OCIAML3	viability	AACAGGTTCTTGGAGTGCTGAGG	SH2D1A	ENSG00000183918	2.28700432345875	[29]	[441]	9	hSpCas9	negative selection	12435178
124370230	124370253	X	+	28162770	OCIAML3	viability	GCATTTCAGAAGCCAGATCAAGG	SH2D1A	ENSG00000183918	0.6861002788685719	[41]	[203]	6	hSpCas9	negative selection	12435179
124346768	124346791	X	-	28162770	OCIAML3	viability	ATCATACTCACAGCACACATAGG	SH2D1A	ENSG00000183918	-0.8284728939611863	[109]	[186]	-6	hSpCas9	negative selection	12435180
124365786	124365809	X	+	28162770	OCIAML3	viability	CGAGTGTCCCAGACAGAAACAGG	SH2D1A	ENSG00000183918	0.696949067495356	[112]	[552]	6	hSpCas9	negative selection	12435181
124370291	124370314	X	-	28162770	OCIAML3	viability	ACCTTGTGTACTTCTAGCTGAGG	SH2D1A	ENSG00000183918	1.5583874365605728	[45]	[408]	9	hSpCas9	negative selection	12435182