Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:57630
• Symbol:SH3RF1
• Description:SH3 domain containing ring finger 1

DataSource: http://genomecrispr.dkfz.de/#!/results/SH3RF1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
169268860	169268883	4	-	26472758	Jiyoye	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	-0.5156567579716669	[181]	[95]	-4	hSpCas9	negative selection	146285
169117720	169117743	4	-	26472758	Jiyoye	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	-0.8715406465601903	[147]	[60]	-6	hSpCas9	negative selection	146286
169156600	169156623	4	-	26472758	Jiyoye	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	1.2007245040384469	[89]	[155]	7	hSpCas9	negative selection	146287
169268900	169268923	4	-	26472758	Jiyoye	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	2.3749949757567235	[33]	[132]	9	hSpCas9	negative selection	146288
169268830	169268853	4	+	26472758	Jiyoye	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	-0.22886130380955205	[114]	[73]	-2	hSpCas9	negative selection	146289
169156535	169156558	4	+	26472758	Jiyoye	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	1.6295678028423215	[92]	[216]	8	hSpCas9	negative selection	146290
169136444	169136467	4	+	26472758	Jiyoye	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.31778019499091514	[318]	[192]	-2	hSpCas9	negative selection	146291
169136404	169136427	4	+	26472758	Jiyoye	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	-0.5710202481757781	[196]	[99]	-4	hSpCas9	negative selection	146292
169130121	169130144	4	+	26472758	Jiyoye	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	2.1816156810907423	[18]	[64]	9	hSpCas9	negative selection	146293
169130071	169130094	4	+	26472758	Jiyoye	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	-1.0567717182539167	[79]	[28]	-6	hSpCas9	negative selection	146294
169268860	169268883	4	-	26472758	KBM7	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	0.05432147796191367	[379,277]	[236,88]	0	hSpCas9	negative selection	337403
169117720	169117743	4	-	26472758	KBM7	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	0.6236219904460384	[260,165]	[200,107]	6	hSpCas9	negative selection	337404
169156600	169156623	4	-	26472758	KBM7	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	0.15692142118864125	[584,457]	[359,191]	1	hSpCas9	negative selection	337405
169268900	169268923	4	-	26472758	KBM7	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	0.8688104562594556	[419,355]	[445,229]	8	hSpCas9	negative selection	337406
169268830	169268853	4	+	26472758	KBM7	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	0.04117315482375583	[352,178]	[171,82]	0	hSpCas9	negative selection	337407
169156535	169156558	4	+	26472758	KBM7	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.1027301685741453	[877,697]	[552,253]	1	hSpCas9	negative selection	337408
169136444	169136467	4	+	26472758	KBM7	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.08497532637103444	[786,819]	[308,487]	0	hSpCas9	negative selection	337409
169136404	169136427	4	+	26472758	KBM7	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	-0.23860623440387607	[637,737]	[219,328]	-2	hSpCas9	negative selection	337410
169130121	169130144	4	+	26472758	KBM7	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	-0.2083864810454814	[129,115]	[30,66]	-2	hSpCas9	negative selection	337411
169130071	169130094	4	+	26472758	KBM7	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.38930030411359284	[285,392]	[166,254]	4	hSpCas9	negative selection	337412
169268860	169268883	4	-	26472758	Raji	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	0.0854687589451589	[198]	[48]	0	hSpCas9	negative selection	528521
169117720	169117743	4	-	26472758	Raji	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	0.5425989165900735	[141]	[47]	5	hSpCas9	negative selection	528522
169156600	169156623	4	-	26472758	Raji	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	0.03606613087194677	[310]	[73]	0	hSpCas9	negative selection	528523
169268900	169268923	4	-	26472758	Raji	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	0.7111232431253839	[228]	[86]	6	hSpCas9	negative selection	528524
169268830	169268853	4	+	26472758	Raji	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	-0.35627266912542316	[170]	[30]	-3	hSpCas9	negative selection	528525
169156535	169156558	4	+	26472758	Raji	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.3000286133159954	[391]	[111]	3	hSpCas9	negative selection	528526
169136444	169136467	4	+	26472758	Raji	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.2401047956639375	[466]	[127]	2	hSpCas9	negative selection	528527
169136404	169136427	4	+	26472758	Raji	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	0.00429004240949582	[347]	[80]	0	hSpCas9	negative selection	528528
169130121	169130144	4	+	26472758	Raji	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	-0.4128732759597413	[108]	[18]	-3	hSpCas9	negative selection	528529
169130071	169130094	4	+	26472758	Raji	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.38094860869956293	[181]	[54]	3	hSpCas9	negative selection	528530
169268860	169268883	4	-	26472758	K562	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	-2.307877584134387	[392]	[66]	-8	hSpCas9	negative selection	719639
169117720	169117743	4	-	26472758	K562	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	0.8060943758516873	[228]	[337]	6	hSpCas9	negative selection	719640
169156600	169156623	4	-	26472758	K562	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	0.4905793149358444	[472]	[560]	4	hSpCas9	negative selection	719641
169268900	169268923	4	-	26472758	K562	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	-0.05219827869172791	[338]	[275]	0	hSpCas9	negative selection	719642
169268830	169268853	4	+	26472758	K562	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	-0.29295431453644905	[163]	[112]	-2	hSpCas9	negative selection	719643
169156535	169156558	4	+	26472758	K562	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.29306789037416336	[553]	[572]	2	hSpCas9	negative selection	719644
169136444	169136467	4	+	26472758	K562	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.05597363825333668	[783]	[687]	0	hSpCas9	negative selection	719645
169136404	169136427	4	+	26472758	K562	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	0.6482238296082169	[547]	[724]	5	hSpCas9	negative selection	719646
169130121	169130144	4	+	26472758	K562	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	1.4503230262143256	[87]	[202]	9	hSpCas9	negative selection	719647
169130071	169130094	4	+	26472758	K562	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.10600469896935194	[316]	[287]	0	hSpCas9	negative selection	719648
169116584	169116607	4	+	26627737	DLD1	viability	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-0.6940775659604671	[246]	[63,68,15]	-6	hSpCas9	negative selection	824413
169117522	169117545	4	-	26627737	DLD1	viability	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.26674494911826396	[1044]	[218,279,309]	-3	hSpCas9	negative selection	824414
169130095	169130118	4	-	26627737	DLD1	viability	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.41102121179586515	[2062]	[1049,903,651]	4	hSpCas9	negative selection	824415
169136559	169136582	4	+	26627737	DLD1	viability	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.3173042511100049	[386]	[155,255,58]	3	hSpCas9	negative selection	824416
169155545	169155568	4	-	26627737	DLD1	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.907966151280749	[713]	[264,593,406]	8	hSpCas9	negative selection	824417
169268962	169268985	4	-	26627737	DLD1	viability	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.7340504774649667	[439]	[206,301,186]	7	hSpCas9	negative selection	824418
169116584	169116607	4	+	26627737	GBM cells	viability after 5 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	0.12671979240849796	[75]	[31,56]	2	hSpCas9	negative selection	906728
169117522	169117545	4	-	26627737	GBM cells	viability after 5 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.018096760443282955	[303]	[151,169]	0	hSpCas9	negative selection	906729
169130095	169130118	4	-	26627737	GBM cells	viability after 5 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.550303737345818	[954]	[779,719]	7	hSpCas9	negative selection	906730
169136559	169136582	4	+	26627737	GBM cells	viability after 5 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.8196871837351105	[130]	[139,107]	9	hSpCas9	negative selection	906731
169155545	169155568	4	-	26627737	GBM cells	viability after 5 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.43740194580734126	[346]	[250,252]	6	hSpCas9	negative selection	906732
169268962	169268985	4	-	26627737	GBM cells	viability after 5 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.08373775270733641	[577]	[263,392]	1	hSpCas9	negative selection	906733
169116584	169116607	4	+	26627737	GBM cells	viability after 13 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	0.4029437462265153	[75]	[64,45]	5	hSpCas9	negative selection	989043
169117522	169117545	4	-	26627737	GBM cells	viability after 13 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.4796795428235741	[303]	[141,98]	-5	hSpCas9	negative selection	989044
169130095	169130118	4	-	26627737	GBM cells	viability after 13 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.4987068690918155	[954]	[719,741]	6	hSpCas9	negative selection	989045
169136559	169136582	4	+	26627737	GBM cells	viability after 13 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	1.4087319208885896	[130]	[239,146]	9	hSpCas9	negative selection	989046
169155545	169155568	4	-	26627737	GBM cells	viability after 13 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.5532187236096733	[346]	[326,234]	7	hSpCas9	negative selection	989047
169268962	169268985	4	-	26627737	GBM cells	viability after 13 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.4371729787619487	[577]	[476,381]	5	hSpCas9	negative selection	989048
169116584	169116607	4	+	26627737	GBM cells	viability after 21 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-0.5291905931996586	[75]	[25,30]	-5	hSpCas9	negative selection	1071358
169117522	169117545	4	-	26627737	GBM cells	viability after 21 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.38634892648007424	[303]	[117,133]	-4	hSpCas9	negative selection	1071359
169130095	169130118	4	-	26627737	GBM cells	viability after 21 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.37278822302857617	[954]	[687,656]	4	hSpCas9	negative selection	1071360
169136559	169136582	4	+	26627737	GBM cells	viability after 21 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.8453067074878206	[130]	[130,124]	8	hSpCas9	negative selection	1071361
169155545	169155568	4	-	26627737	GBM cells	viability after 21 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.8872840009267398	[346]	[390,309]	8	hSpCas9	negative selection	1071362
169268962	169268985	4	-	26627737	GBM cells	viability after 21 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.18279606963608974	[577]	[357,354]	2	hSpCas9	negative selection	1071363
169116584	169116607	4	+	26627737	RPE1	viability after 9 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-3.212664821411214	[429]	[24,0]	-9	hSpCas9	negative selection	1153673
169117522	169117545	4	-	26627737	RPE1	viability after 9 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.33628936791131253	[1355]	[244,453]	-2	hSpCas9	negative selection	1153674
169130095	169130118	4	-	26627737	RPE1	viability after 9 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	1.5747484617415468	[1804]	[1836,1484]	8	hSpCas9	negative selection	1153675
169136559	169136582	4	+	26627737	RPE1	viability after 9 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.825690634926528	[607]	[270,422]	5	hSpCas9	negative selection	1153676
169155545	169155568	4	-	26627737	RPE1	viability after 9 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.13659194302049604	[1366]	[359,612]	1	hSpCas9	negative selection	1153677
169268962	169268985	4	-	26627737	RPE1	viability after 9 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	-0.5480698479945068	[1476]	[255,393]	-4	hSpCas9	negative selection	1153678
169116584	169116607	4	+	26627737	RPE1	viability after 12 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-2.6437425528687815	[429]	[34,0]	-9	hSpCas9	negative selection	1235988
169117522	169117545	4	-	26627737	RPE1	viability after 12 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.9163594556067868	[1355]	[176,209]	-6	hSpCas9	negative selection	1235989
169130095	169130118	4	-	26627737	RPE1	viability after 12 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	1.7167900630414579	[1804]	[1713,1466]	8	hSpCas9	negative selection	1235990
169136559	169136582	4	+	26627737	RPE1	viability after 12 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.2789970505286779	[607]	[136,262]	2	hSpCas9	negative selection	1235991
169155545	169155568	4	-	26627737	RPE1	viability after 12 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.24598475993427948	[1366]	[453,415]	1	hSpCas9	negative selection	1235992
169268962	169268985	4	-	26627737	RPE1	viability after 12 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	-0.1715065419294426	[1476]	[312,393]	-1	hSpCas9	negative selection	1235993
169116584	169116607	4	+	26627737	RPE1	viability after 15 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-2.409852605326146	[429]	[0,43]	-8	hSpCas9	negative selection	1318303
169117522	169117545	4	-	26627737	RPE1	viability after 15 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-1.1298705408419132	[1355]	[46,298]	-6	hSpCas9	negative selection	1318304
169130095	169130118	4	-	26627737	RPE1	viability after 15 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	1.3121245808292668	[1804]	[1332,1204]	7	hSpCas9	negative selection	1318305
169136559	169136582	4	+	26627737	RPE1	viability after 15 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	1.1892138218688104	[607]	[437,347]	6	hSpCas9	negative selection	1318306
169155545	169155568	4	-	26627737	RPE1	viability after 15 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.32016830894840553	[1366]	[438,524]	2	hSpCas9	negative selection	1318307
169268962	169268985	4	-	26627737	RPE1	viability after 15 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	-0.5971404545624335	[1476]	[264,286]	-4	hSpCas9	negative selection	1318308
169116584	169116607	4	+	26627737	RPE1	viability after 18 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-2.997011326928883	[429]	[0,28]	-9	hSpCas9	negative selection	1400618
169117522	169117545	4	-	26627737	RPE1	viability after 18 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.6595862123009424	[1355]	[148,319]	-4	hSpCas9	negative selection	1400619
169130095	169130118	4	-	26627737	RPE1	viability after 18 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	1.7722796564865235	[1804]	[1778,1540]	8	hSpCas9	negative selection	1400620
169136559	169136582	4	+	26627737	RPE1	viability after 18 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.9511147241883597	[607]	[250,387]	5	hSpCas9	negative selection	1400621
169155545	169155568	4	-	26627737	RPE1	viability after 18 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.057263335898181444	[1366]	[291,481]	0	hSpCas9	negative selection	1400622
169268962	169268985	4	-	26627737	RPE1	viability after 18 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	-0.4890387311593646	[1476]	[283,283]	-3	hSpCas9	negative selection	1400623
169116584	169116607	4	+	26627737	HeLa	viability after 8 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-0.8009455088468289	[293]	[16,74,112]	-7	hSpCas9	negative selection	1482933
169117522	169117545	4	-	26627737	HeLa	viability after 8 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.7368961148969254	[525]	[191,108,123]	-6	hSpCas9	negative selection	1482934
169130095	169130118	4	-	26627737	HeLa	viability after 8 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.9155095152586339	[1261]	[1303,997,875]	7	hSpCas9	negative selection	1482935
169136559	169136582	4	+	26627737	HeLa	viability after 8 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	-0.2160355839567808	[200]	[80,38,104]	-2	hSpCas9	negative selection	1482936
169155545	169155568	4	-	26627737	HeLa	viability after 8 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.586609489984657	[502]	[325,323,334]	5	hSpCas9	negative selection	1482937
169268962	169268985	4	-	26627737	HeLa	viability after 8 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.5723570671480633	[393]	[353,168,262]	5	hSpCas9	negative selection	1482938
169116584	169116607	4	+	26627737	HeLa	viability after 12 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-0.08534674901263567	[293]	[154,45,150]	0	hSpCas9	negative selection	1565248
169117522	169117545	4	-	26627737	HeLa	viability after 12 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.5183717957611494	[525]	[47,210,186]	-4	hSpCas9	negative selection	1565249
169130095	169130118	4	-	26627737	HeLa	viability after 12 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.22072677309004662	[1261]	[497,636,681]	2	hSpCas9	negative selection	1565250
169136559	169136582	4	+	26627737	HeLa	viability after 12 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.5431506171471159	[200]	[0,126,230]	4	hSpCas9	negative selection	1565251
169155545	169155568	4	-	26627737	HeLa	viability after 12 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.23881790383707116	[502]	[90,128,310]	-2	hSpCas9	negative selection	1565252
169268962	169268985	4	-	26627737	HeLa	viability after 12 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.6333416099515038	[393]	[355,230,175]	5	hSpCas9	negative selection	1565253
169116584	169116607	4	+	26627737	HeLa	viability after 15 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-1.8491969507742	[293]	[65,26,3]	-9	hSpCas9	negative selection	1647563
169117522	169117545	4	-	26627737	HeLa	viability after 15 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	0.20887115198460893	[525]	[180,318,242]	1	hSpCas9	negative selection	1647564
169130095	169130118	4	-	26627737	HeLa	viability after 15 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.8964450451740602	[1261]	[847,938,1093]	6	hSpCas9	negative selection	1647565
169136559	169136582	4	+	26627737	HeLa	viability after 15 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.9918558075888316	[200]	[14,204,278]	7	hSpCas9	negative selection	1647566
169155545	169155568	4	-	26627737	HeLa	viability after 15 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.3180727466177727	[502]	[138,33,332]	-3	hSpCas9	negative selection	1647567
169268962	169268985	4	-	26627737	HeLa	viability after 15 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.2772601933778095	[393]	[103,313,163]	2	hSpCas9	negative selection	1647568
169116584	169116607	4	+	26627737	HeLa	viability after 18 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-1.907731824515378	[293]	[41,21,3]	-9	hSpCas9	negative selection	1729878
169117522	169117545	4	-	26627737	HeLa	viability after 18 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	0.21617297191445084	[525]	[119,268,242]	1	hSpCas9	negative selection	1729879
169130095	169130118	4	-	26627737	HeLa	viability after 18 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.8852391011903233	[1261]	[558,771,1093]	6	hSpCas9	negative selection	1729880
169136559	169136582	4	+	26627737	HeLa	viability after 18 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.987927713544203	[200]	[8,169,278]	7	hSpCas9	negative selection	1729881
169155545	169155568	4	-	26627737	HeLa	viability after 18 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.3045306974194965	[502]	[97,25,332]	-3	hSpCas9	negative selection	1729882
169268962	169268985	4	-	26627737	HeLa	viability after 18 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.3415092638605611	[393]	[78,269,163]	3	hSpCas9	negative selection	1729883
169116584	169116607	4	+	26627737	HCT116	viability after 6 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	1.6079159534022585	[110]	[116,17]	8	hSpCas9	negative selection	1812193
169117522	169117545	4	-	26627737	HCT116	viability after 6 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	0.5432841369304395	[901]	[477,56]	3	hSpCas9	negative selection	1812194
169130095	169130118	4	-	26627737	HCT116	viability after 6 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.5957588643783542	[2348]	[1016,304]	3	hSpCas9	negative selection	1812195
169136559	169136582	4	+	26627737	HCT116	viability after 6 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	1.832036784228225	[346]	[190,195]	8	hSpCas9	negative selection	1812196
169155545	169155568	4	-	26627737	HCT116	viability after 6 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-1.9123765547316263	[919]	[40,36]	-8	hSpCas9	negative selection	1812197
169268962	169268985	4	-	26627737	HCT116	viability after 6 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	1.3673261307063724	[1496]	[737,534]	7	hSpCas9	negative selection	1812198
169116584	169116607	4	+	26627737	HCT116	viability after 8 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-0.3982737463416306	[151]	[51,37,99]	-5	hSpCas9	negative selection	1894508
169117522	169117545	4	-	26627737	HCT116	viability after 8 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	0.2668591831161385	[331]	[202,151,303]	3	hSpCas9	negative selection	1894509
169130095	169130118	4	-	26627737	HCT116	viability after 8 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	-0.05282025023198056	[1395]	[924,477,823]	0	hSpCas9	negative selection	1894510
169136559	169136582	4	+	26627737	HCT116	viability after 8 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	-0.13958648597516676	[235]	[153,99,100]	-1	hSpCas9	negative selection	1894511
169155545	169155568	4	-	26627737	HCT116	viability after 8 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.49634129446487635	[581]	[242,268,170]	-5	hSpCas9	negative selection	1894512
169268962	169268985	4	-	26627737	HCT116	viability after 8 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	-0.3196582092927127	[664]	[242,349,286]	-4	hSpCas9	negative selection	1894513
169116584	169116607	4	+	26627737	HCT116	viability after 9 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	0.9595633557689303	[110]	[103,20]	6	hSpCas9	negative selection	1976823
169117522	169117545	4	-	26627737	HCT116	viability after 9 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.016630048874743508	[901]	[241,234]	0	hSpCas9	negative selection	1976824
169130095	169130118	4	-	26627737	HCT116	viability after 9 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.41569903025348065	[2348]	[1163,577]	3	hSpCas9	negative selection	1976825
169136559	169136582	4	+	26627737	HCT116	viability after 9 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.23783613059619335	[346]	[101,114]	1	hSpCas9	negative selection	1976826
169155545	169155568	4	-	26627737	HCT116	viability after 9 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.368781500809481	[919]	[257,363]	2	hSpCas9	negative selection	1976827
169268962	169268985	4	-	26627737	HCT116	viability after 9 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	-1.082346508973633	[1496]	[271,122]	-6	hSpCas9	negative selection	1976828
169116584	169116607	4	+	26627737	HCT116	viability after 12 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-0.3798124562503755	[151]	[55,75,52]	-4	hSpCas9	negative selection	2059138
169117522	169117545	4	-	26627737	HCT116	viability after 12 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	0.45735132015505137	[331]	[223,237,257]	4	hSpCas9	negative selection	2059139
169130095	169130118	4	-	26627737	HCT116	viability after 12 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	-0.02201109312456806	[1395]	[687,820,663]	0	hSpCas9	negative selection	2059140
169136559	169136582	4	+	26627737	HCT116	viability after 12 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	-0.5384165807261252	[235]	[66,134,56]	-5	hSpCas9	negative selection	2059141
169155545	169155568	4	-	26627737	HCT116	viability after 12 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.5043106524078196	[581]	[160,269,221]	-5	hSpCas9	negative selection	2059142
169268962	169268985	4	-	26627737	HCT116	viability after 12 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	-0.6701915751898433	[664]	[144,243,276]	-6	hSpCas9	negative selection	2059143
169116584	169116607	4	+	26627737	HCT116	viability after 15 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	0.5606242426908048	[151]	[55,76,242]	5	hSpCas9	negative selection	2141453
169117522	169117545	4	-	26627737	HCT116	viability after 15 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	0.511441859999	[331]	[273,299,241]	5	hSpCas9	negative selection	2141454
169130095	169130118	4	-	26627737	HCT116	viability after 15 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	-0.030714798842641056	[1395]	[741,799,806]	0	hSpCas9	negative selection	2141455
169136559	169136582	4	+	26627737	HCT116	viability after 15 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	-0.43538747381827675	[235]	[83,138,75]	-4	hSpCas9	negative selection	2141456
169155545	169155568	4	-	26627737	HCT116	viability after 15 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.6367747135492658	[581]	[257,165,225]	-6	hSpCas9	negative selection	2141457
169268962	169268985	4	-	26627737	HCT116	viability after 15 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	-1.0612712676222473	[664]	[186,135,225]	-8	hSpCas9	negative selection	2141458
169116584	169116607	4	+	26627737	HCT116	viability after 18 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	-0.12123404948051864	[151]	[76,60,64]	-1	hSpCas9	negative selection	2223768
169117522	169117545	4	-	26627737	HCT116	viability after 18 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	0.230692796302302	[331]	[253,92,225]	2	hSpCas9	negative selection	2223769
169130095	169130118	4	-	26627737	HCT116	viability after 18 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.4370961376430622	[1395]	[909,856,980]	4	hSpCas9	negative selection	2223770
169136559	169136582	4	+	26627737	HCT116	viability after 18 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	-0.8070956453752642	[235]	[28,93,70]	-6	hSpCas9	negative selection	2223771
169155545	169155568	4	-	26627737	HCT116	viability after 18 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.9464308173785491	[581]	[108,109,224]	-7	hSpCas9	negative selection	2223772
169268962	169268985	4	-	26627737	HCT116	viability after 18 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	-1.3169813323602344	[664]	[127,61,204]	-8	hSpCas9	negative selection	2223773
169165578	169165601	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCACTGCACTCCAGCCTAG	SH3RF1	ENSG00000154447	-0.41902599900673143	[34,218]	[4,37]	-2	dCas9-VP64	positive selection	2439531
169235765	169235788	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCGCCTCCCCAG	SH3RF1	ENSG00000154447	0.6259309833286419	[228,309]	[35,151]	2	dCas9-VP64	positive selection	2450451
169165578	169165601	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCACTGCACTCCAGCCTAG	SH3RF1	ENSG00000154447	0.0771162345407751	[282,156]	[110,43]	0	dCas9-VP64	positive selection	2534786
169235765	169235788	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCGCCTCCCCAG	SH3RF1	ENSG00000154447	0.8832307312434098	[227,267]	[69,222]	6	dCas9-VP64	positive selection	2545706
169155545	169155568	4	-	27260157	DLD1	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.799671120994615	[]	[]	9	hSpCas9	negative selection	2573599
169117735	169117758	4	-	27260157	DLD1	viability	AAAGTCCCTATGTCTACAGCTGG	SH3RF1	ENSG00000154447	1.15112046193933	[]	[]	9	hSpCas9	negative selection	2573655
169269054	169269077	4	-	27260157	DLD1	viability	AACTCAGATGTCCCGAGTGCAGG	SH3RF1	ENSG00000154447	-0.581504143570779	[]	[]	-5	hSpCas9	negative selection	2578229
169122116	169122139	4	+	27260157	DLD1	viability	GCGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	-0.331529033606824	[]	[]	-3	hSpCas9	negative selection	2578874
169269043	169269066	4	-	27260157	DLD1	viability	CCCGAGTGCAGGACTCTTGTTGG	SH3RF1	ENSG00000154447	-0.364979150734847	[]	[]	-3	hSpCas9	negative selection	2579140
169116613	169116636	4	-	27260157	DLD1	viability	ACTAGTTGCAGCGCACAACCAGG	SH3RF1	ENSG00000154447	-0.186853666493174	[]	[]	-1	hSpCas9	negative selection	2582647
169136496	169136519	4	+	27260157	DLD1	viability	TTCTTGGTGTCGGAGTGCTTTGG	SH3RF1	ENSG00000154447	-0.0226495903362586	[]	[]	0	hSpCas9	negative selection	2582788
169269029	169269052	4	-	27260157	DLD1	viability	TCTTGTTGGCTCGGGTGTCGAGG	SH3RF1	ENSG00000154447	0.0916032862241414	[]	[]	3	hSpCas9	negative selection	2584036
169268847	169268870	4	+	27260157	DLD1	viability	CCGAGGCTGCTGTCCGCCCTGGG	SH3RF1	ENSG00000154447	0.43840173918035	[]	[]	7	hSpCas9	negative selection	2585689
169117563	169117586	4	-	27260157	DLD1	viability	AGGTCTTGTTGCACATGACGGGG	SH3RF1	ENSG00000154447	-2.07984922730301	[]	[]	-8	hSpCas9	negative selection	2587479
169117527	169117550	4	-	27260157	DLD1	viability	ACCAGGCCCGCAATGCTGTGAGG	SH3RF1	ENSG00000154447	0.574754376972576	[]	[]	8	hSpCas9	negative selection	2604782
169136568	169136591	4	-	27260157	DLD1	viability	TGGGATAAGCCTCCTGTGCCAGG	SH3RF1	ENSG00000154447	1.2292810020994	[]	[]	9	hSpCas9	negative selection	2607482
169136342	169136365	4	-	27260157	DLD1	viability	CACGGATCAGCGAGCTGTCTGGG	SH3RF1	ENSG00000154447	1.05356937190928	[]	[]	9	hSpCas9	negative selection	2609610
169136419	169136442	4	+	27260157	DLD1	viability	AGTGGCGGTTCTGGGATGCCTGG	SH3RF1	ENSG00000154447	-0.334002326639417	[]	[]	-3	hSpCas9	negative selection	2613595
169269154	169269177	4	+	27260157	DLD1	viability	TCAAGGCGCTCTAGACACACCGG	SH3RF1	ENSG00000154447	-0.880877872828309	[]	[]	-6	hSpCas9	negative selection	2614413
169269096	169269119	4	-	27260157	DLD1	viability	TTTGCAAGCGATGTTTGCTGGGG	SH3RF1	ENSG00000154447	-0.290589985297188	[]	[]	-2	hSpCas9	negative selection	2617420
169116562	169116585	4	+	27260157	DLD1	viability	GGCCGGCGGCATTCTGTACCTGG	SH3RF1	ENSG00000154447	0.731340947697376	[]	[]	8	hSpCas9	negative selection	2621630
169120894	169120917	4	-	27260157	DLD1	viability	GTGTTTGAGCGCTGCCAGGATGG	SH3RF1	ENSG00000154447	0.366500968776351	[]	[]	4	hSpCas9	negative selection	2645918
169269137	169269160	4	+	27260157	DLD1	viability	AGACCTTCGCAGAAGCATCAAGG	SH3RF1	ENSG00000154447	1.52192466443573	[]	[]	9	hSpCas9	negative selection	2648891
169120942	169120965	4	+	27260157	DLD1	viability	TCTAGTTCATCCTCTTTCCGAGG	SH3RF1	ENSG00000154447	-0.05967879011048	[]	[]	0	hSpCas9	negative selection	2649661
169155545	169155568	4	-	27260157	HT1080	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.261851897145465	[]	[]	2	hSpCas9	negative selection	2649729
169117735	169117758	4	-	27260157	HT1080	viability	AAAGTCCCTATGTCTACAGCTGG	SH3RF1	ENSG00000154447	0.935658473566442	[]	[]	7	hSpCas9	negative selection	2649785
169269054	169269077	4	-	27260157	HT1080	viability	AACTCAGATGTCCCGAGTGCAGG	SH3RF1	ENSG00000154447	0.262292122756548	[]	[]	2	hSpCas9	negative selection	2654359
169122116	169122139	4	+	27260157	HT1080	viability	GCGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	-1.026303436972	[]	[]	-8	hSpCas9	negative selection	2655004
169269043	169269066	4	-	27260157	HT1080	viability	CCCGAGTGCAGGACTCTTGTTGG	SH3RF1	ENSG00000154447	-0.12689378054778	[]	[]	0	hSpCas9	negative selection	2655270
169116613	169116636	4	-	27260157	HT1080	viability	ACTAGTTGCAGCGCACAACCAGG	SH3RF1	ENSG00000154447	0.212420536212967	[]	[]	2	hSpCas9	negative selection	2658777
169136496	169136519	4	+	27260157	HT1080	viability	TTCTTGGTGTCGGAGTGCTTTGG	SH3RF1	ENSG00000154447	0.639940007489411	[]	[]	5	hSpCas9	negative selection	2658918
169269029	169269052	4	-	27260157	HT1080	viability	TCTTGTTGGCTCGGGTGTCGAGG	SH3RF1	ENSG00000154447	-0.796671887373422	[]	[]	-8	hSpCas9	negative selection	2660166
169268847	169268870	4	+	27260157	HT1080	viability	CCGAGGCTGCTGTCCGCCCTGGG	SH3RF1	ENSG00000154447	1.17680680148281	[]	[]	8	hSpCas9	negative selection	2661819
169117563	169117586	4	-	27260157	HT1080	viability	AGGTCTTGTTGCACATGACGGGG	SH3RF1	ENSG00000154447	-1.26998160471302	[]	[]	-9	hSpCas9	negative selection	2663609
169117527	169117550	4	-	27260157	HT1080	viability	ACCAGGCCCGCAATGCTGTGAGG	SH3RF1	ENSG00000154447	1.11613171756517	[]	[]	8	hSpCas9	negative selection	2680912
169136568	169136591	4	-	27260157	HT1080	viability	TGGGATAAGCCTCCTGTGCCAGG	SH3RF1	ENSG00000154447	1.18682982686505	[]	[]	8	hSpCas9	negative selection	2683612
169136342	169136365	4	-	27260157	HT1080	viability	CACGGATCAGCGAGCTGTCTGGG	SH3RF1	ENSG00000154447	0.122030131176968	[]	[]	1	hSpCas9	negative selection	2685740
169136419	169136442	4	+	27260157	HT1080	viability	AGTGGCGGTTCTGGGATGCCTGG	SH3RF1	ENSG00000154447	0.346903648490659	[]	[]	3	hSpCas9	negative selection	2689725
169269154	169269177	4	+	27260157	HT1080	viability	TCAAGGCGCTCTAGACACACCGG	SH3RF1	ENSG00000154447	-0.466226687741423	[]	[]	-7	hSpCas9	negative selection	2690543
169269096	169269119	4	-	27260157	HT1080	viability	TTTGCAAGCGATGTTTGCTGGGG	SH3RF1	ENSG00000154447	0.176522093626196	[]	[]	1	hSpCas9	negative selection	2693550
169116562	169116585	4	+	27260157	HT1080	viability	GGCCGGCGGCATTCTGTACCTGG	SH3RF1	ENSG00000154447	0.607524622466642	[]	[]	5	hSpCas9	negative selection	2697760
169120894	169120917	4	-	27260157	HT1080	viability	GTGTTTGAGCGCTGCCAGGATGG	SH3RF1	ENSG00000154447	0.256600865729444	[]	[]	2	hSpCas9	negative selection	2722048
169269137	169269160	4	+	27260157	HT1080	viability	AGACCTTCGCAGAAGCATCAAGG	SH3RF1	ENSG00000154447	1.51185341802909	[]	[]	9	hSpCas9	negative selection	2725021
169120942	169120965	4	+	27260157	HT1080	viability	TCTAGTTCATCCTCTTTCCGAGG	SH3RF1	ENSG00000154447	1.18380662722014	[]	[]	8	hSpCas9	negative selection	2725791
169155545	169155568	4	-	27260157	MKN45	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	1.0735358558912	[]	[]	8	hSpCas9	negative selection	2725859
169117735	169117758	4	-	27260157	MKN45	viability	AAAGTCCCTATGTCTACAGCTGG	SH3RF1	ENSG00000154447	1.0314898594961	[]	[]	8	hSpCas9	negative selection	2725915
169269054	169269077	4	-	27260157	MKN45	viability	AACTCAGATGTCCCGAGTGCAGG	SH3RF1	ENSG00000154447	0.165860192257419	[]	[]	5	hSpCas9	negative selection	2730489
169122116	169122139	4	+	27260157	MKN45	viability	GCGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	-1.38477833207513	[]	[]	-8	hSpCas9	negative selection	2731134
169269043	169269066	4	-	27260157	MKN45	viability	CCCGAGTGCAGGACTCTTGTTGG	SH3RF1	ENSG00000154447	0.0494532076923208	[]	[]	0	hSpCas9	negative selection	2731400
169116613	169116636	4	-	27260157	MKN45	viability	ACTAGTTGCAGCGCACAACCAGG	SH3RF1	ENSG00000154447	0.480806742906803	[]	[]	6	hSpCas9	negative selection	2734907
169136496	169136519	4	+	27260157	MKN45	viability	TTCTTGGTGTCGGAGTGCTTTGG	SH3RF1	ENSG00000154447	0.129133505814275	[]	[]	4	hSpCas9	negative selection	2735048
169269029	169269052	4	-	27260157	MKN45	viability	TCTTGTTGGCTCGGGTGTCGAGG	SH3RF1	ENSG00000154447	-1.29272393587577	[]	[]	-8	hSpCas9	negative selection	2736296
169268847	169268870	4	+	27260157	MKN45	viability	CCGAGGCTGCTGTCCGCCCTGGG	SH3RF1	ENSG00000154447	0.761106773983043	[]	[]	7	hSpCas9	negative selection	2737949
169117563	169117586	4	-	27260157	MKN45	viability	AGGTCTTGTTGCACATGACGGGG	SH3RF1	ENSG00000154447	-0.836370532560993	[]	[]	-7	hSpCas9	negative selection	2739739
169117527	169117550	4	-	27260157	MKN45	viability	ACCAGGCCCGCAATGCTGTGAGG	SH3RF1	ENSG00000154447	-0.288764884140706	[]	[]	-1	hSpCas9	negative selection	2757042
169136568	169136591	4	-	27260157	MKN45	viability	TGGGATAAGCCTCCTGTGCCAGG	SH3RF1	ENSG00000154447	1.39340967727732	[]	[]	9	hSpCas9	negative selection	2759742
169136342	169136365	4	-	27260157	MKN45	viability	CACGGATCAGCGAGCTGTCTGGG	SH3RF1	ENSG00000154447	1.18892339235391	[]	[]	9	hSpCas9	negative selection	2761870
169136419	169136442	4	+	27260157	MKN45	viability	AGTGGCGGTTCTGGGATGCCTGG	SH3RF1	ENSG00000154447	1.40611199271778	[]	[]	9	hSpCas9	negative selection	2765855
169269154	169269177	4	+	27260157	MKN45	viability	TCAAGGCGCTCTAGACACACCGG	SH3RF1	ENSG00000154447	-0.471670306816634	[]	[]	-6	hSpCas9	negative selection	2766673
169269096	169269119	4	-	27260157	MKN45	viability	TTTGCAAGCGATGTTTGCTGGGG	SH3RF1	ENSG00000154447	-0.119524456249907	[]	[]	0	hSpCas9	negative selection	2769680
169116562	169116585	4	+	27260157	MKN45	viability	GGCCGGCGGCATTCTGTACCTGG	SH3RF1	ENSG00000154447	0.37951163023859	[]	[]	6	hSpCas9	negative selection	2773890
169120894	169120917	4	-	27260157	MKN45	viability	GTGTTTGAGCGCTGCCAGGATGG	SH3RF1	ENSG00000154447	-0.256075386866794	[]	[]	-1	hSpCas9	negative selection	2798178
169269137	169269160	4	+	27260157	MKN45	viability	AGACCTTCGCAGAAGCATCAAGG	SH3RF1	ENSG00000154447	1.78642253037717	[]	[]	9	hSpCas9	negative selection	2801151
169120942	169120965	4	+	27260157	MKN45	viability	TCTAGTTCATCCTCTTTCCGAGG	SH3RF1	ENSG00000154447	-0.0319168423746847	[]	[]	0	hSpCas9	negative selection	2801921
169155545	169155568	4	-	27260157	RKO	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.456227265448642	[]	[]	2	hSpCas9	negative selection	2801989
169117735	169117758	4	-	27260157	RKO	viability	AAAGTCCCTATGTCTACAGCTGG	SH3RF1	ENSG00000154447	0.286044020735698	[]	[]	1	hSpCas9	negative selection	2802045
169269054	169269077	4	-	27260157	RKO	viability	AACTCAGATGTCCCGAGTGCAGG	SH3RF1	ENSG00000154447	0.274176709609024	[]	[]	1	hSpCas9	negative selection	2806619
169122116	169122139	4	+	27260157	RKO	viability	GCGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	-0.730757716176533	[]	[]	-7	hSpCas9	negative selection	2807264
169269043	169269066	4	-	27260157	RKO	viability	CCCGAGTGCAGGACTCTTGTTGG	SH3RF1	ENSG00000154447	-0.145692017415101	[]	[]	0	hSpCas9	negative selection	2807530
169116613	169116636	4	-	27260157	RKO	viability	ACTAGTTGCAGCGCACAACCAGG	SH3RF1	ENSG00000154447	0.600454152504747	[]	[]	3	hSpCas9	negative selection	2811037
169136496	169136519	4	+	27260157	RKO	viability	TTCTTGGTGTCGGAGTGCTTTGG	SH3RF1	ENSG00000154447	0.30055793082995	[]	[]	1	hSpCas9	negative selection	2811178
169269029	169269052	4	-	27260157	RKO	viability	TCTTGTTGGCTCGGGTGTCGAGG	SH3RF1	ENSG00000154447	-0.562455551235676	[]	[]	-7	hSpCas9	negative selection	2812426
169268847	169268870	4	+	27260157	RKO	viability	CCGAGGCTGCTGTCCGCCCTGGG	SH3RF1	ENSG00000154447	0.757718295661024	[]	[]	8	hSpCas9	negative selection	2814079
169117563	169117586	4	-	27260157	RKO	viability	AGGTCTTGTTGCACATGACGGGG	SH3RF1	ENSG00000154447	0.427273282880772	[]	[]	2	hSpCas9	negative selection	2815869
169117527	169117550	4	-	27260157	RKO	viability	ACCAGGCCCGCAATGCTGTGAGG	SH3RF1	ENSG00000154447	0.470185432274151	[]	[]	2	hSpCas9	negative selection	2833172
169136568	169136591	4	-	27260157	RKO	viability	TGGGATAAGCCTCCTGTGCCAGG	SH3RF1	ENSG00000154447	1.25768715680225	[]	[]	9	hSpCas9	negative selection	2835872
169136342	169136365	4	-	27260157	RKO	viability	CACGGATCAGCGAGCTGTCTGGG	SH3RF1	ENSG00000154447	1.2052962089219	[]	[]	9	hSpCas9	negative selection	2838000
169136419	169136442	4	+	27260157	RKO	viability	AGTGGCGGTTCTGGGATGCCTGG	SH3RF1	ENSG00000154447	-4.09507455697823	[]	[]	-9	hSpCas9	negative selection	2841985
169269154	169269177	4	+	27260157	RKO	viability	TCAAGGCGCTCTAGACACACCGG	SH3RF1	ENSG00000154447	-0.481521671925546	[]	[]	-6	hSpCas9	negative selection	2842803
169269096	169269119	4	-	27260157	RKO	viability	TTTGCAAGCGATGTTTGCTGGGG	SH3RF1	ENSG00000154447	-0.283874091082743	[]	[]	-5	hSpCas9	negative selection	2845810
169116562	169116585	4	+	27260157	RKO	viability	GGCCGGCGGCATTCTGTACCTGG	SH3RF1	ENSG00000154447	-0.904831317478051	[]	[]	-8	hSpCas9	negative selection	2850020
169120894	169120917	4	-	27260157	RKO	viability	GTGTTTGAGCGCTGCCAGGATGG	SH3RF1	ENSG00000154447	0.0642587085111454	[]	[]	0	hSpCas9	negative selection	2874308
169269137	169269160	4	+	27260157	RKO	viability	AGACCTTCGCAGAAGCATCAAGG	SH3RF1	ENSG00000154447	1.36035206390803	[]	[]	9	hSpCas9	negative selection	2877281
169120942	169120965	4	+	27260157	RKO	viability	TCTAGTTCATCCTCTTTCCGAGG	SH3RF1	ENSG00000154447	0.460376161411599	[]	[]	2	hSpCas9	negative selection	2878051
169155545	169155568	4	-	27260157	SF268	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.299542508000764	[]	[]	4	hSpCas9	negative selection	2878119
169117735	169117758	4	-	27260157	SF268	viability	AAAGTCCCTATGTCTACAGCTGG	SH3RF1	ENSG00000154447	0.0936328003593717	[]	[]	0	hSpCas9	negative selection	2878175
169269054	169269077	4	-	27260157	SF268	viability	AACTCAGATGTCCCGAGTGCAGG	SH3RF1	ENSG00000154447	0.190339171338227	[]	[]	0	hSpCas9	negative selection	2882749
169122116	169122139	4	+	27260157	SF268	viability	GCGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	-1.13811790189252	[]	[]	-7	hSpCas9	negative selection	2883394
169269043	169269066	4	-	27260157	SF268	viability	CCCGAGTGCAGGACTCTTGTTGG	SH3RF1	ENSG00000154447	0.310050883797541	[]	[]	4	hSpCas9	negative selection	2883660
169116613	169116636	4	-	27260157	SF268	viability	ACTAGTTGCAGCGCACAACCAGG	SH3RF1	ENSG00000154447	0.0085151662250978	[]	[]	0	hSpCas9	negative selection	2887167
169136496	169136519	4	+	27260157	SF268	viability	TTCTTGGTGTCGGAGTGCTTTGG	SH3RF1	ENSG00000154447	0.680394589302112	[]	[]	8	hSpCas9	negative selection	2887308
169269029	169269052	4	-	27260157	SF268	viability	TCTTGTTGGCTCGGGTGTCGAGG	SH3RF1	ENSG00000154447	-0.261193847460721	[]	[]	-2	hSpCas9	negative selection	2888556
169268847	169268870	4	+	27260157	SF268	viability	CCGAGGCTGCTGTCCGCCCTGGG	SH3RF1	ENSG00000154447	0.989486504568265	[]	[]	9	hSpCas9	negative selection	2890209
169117563	169117586	4	-	27260157	SF268	viability	AGGTCTTGTTGCACATGACGGGG	SH3RF1	ENSG00000154447	-0.985789750097445	[]	[]	-7	hSpCas9	negative selection	2891999
169117527	169117550	4	-	27260157	SF268	viability	ACCAGGCCCGCAATGCTGTGAGG	SH3RF1	ENSG00000154447	0.96199711550664	[]	[]	9	hSpCas9	negative selection	2909302
169136568	169136591	4	-	27260157	SF268	viability	TGGGATAAGCCTCCTGTGCCAGG	SH3RF1	ENSG00000154447	1.51765821725635	[]	[]	9	hSpCas9	negative selection	2912002
169136342	169136365	4	-	27260157	SF268	viability	CACGGATCAGCGAGCTGTCTGGG	SH3RF1	ENSG00000154447	0.503162395704055	[]	[]	7	hSpCas9	negative selection	2914130
169136419	169136442	4	+	27260157	SF268	viability	AGTGGCGGTTCTGGGATGCCTGG	SH3RF1	ENSG00000154447	0.860758396772162	[]	[]	9	hSpCas9	negative selection	2918115
169269154	169269177	4	+	27260157	SF268	viability	TCAAGGCGCTCTAGACACACCGG	SH3RF1	ENSG00000154447	-0.514923674916797	[]	[]	-4	hSpCas9	negative selection	2918933
169269096	169269119	4	-	27260157	SF268	viability	TTTGCAAGCGATGTTTGCTGGGG	SH3RF1	ENSG00000154447	-0.163650089119377	[]	[]	-1	hSpCas9	negative selection	2921940
169116562	169116585	4	+	27260157	SF268	viability	GGCCGGCGGCATTCTGTACCTGG	SH3RF1	ENSG00000154447	0.73846145793484	[]	[]	8	hSpCas9	negative selection	2926150
169120894	169120917	4	-	27260157	SF268	viability	GTGTTTGAGCGCTGCCAGGATGG	SH3RF1	ENSG00000154447	0.0898687108965422	[]	[]	0	hSpCas9	negative selection	2950438
169269137	169269160	4	+	27260157	SF268	viability	AGACCTTCGCAGAAGCATCAAGG	SH3RF1	ENSG00000154447	1.59749141013463	[]	[]	9	hSpCas9	negative selection	2953411
169120942	169120965	4	+	27260157	SF268	viability	TCTAGTTCATCCTCTTTCCGAGG	SH3RF1	ENSG00000154447	-0.363959185447607	[]	[]	-3	hSpCas9	negative selection	2954181
169136480	169136503	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAAGAAGAACACCAAAAAGCGG	SH3RF1	ENSG00000154447	0.11526558745265558	[4,4]	[4,4]	2	hSpCas9	positive selection	3020092
169136360	169136383	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAACCCCACTGCTGCTGCACGG	SH3RF1	ENSG00000154447	0.09154616347388533	[4,4]	[4,4]	2	hSpCas9	positive selection	3020093
169156536	169156559	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.2204972241942748	[4,4]	[4,4]	5	hSpCas9	positive selection	3020094
169155545	169155568	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.06761119084676695	[3,3]	[4,1]	-1	hSpCas9	positive selection	3020095
169136480	169136503	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAAGAAGAACACCAAAAAGCGG	SH3RF1	ENSG00000154447	-0.24011871604097557	[4,4]	[4,1]	-4	hSpCas9	positive selection	3087950
169136360	169136383	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAACCCCACTGCTGCTGCACGG	SH3RF1	ENSG00000154447	0.300504451277958	[4,4]	[5,3]	5	hSpCas9	positive selection	3087951
169156536	169156559	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.16440762453023322	[4,4]	[4,2]	3	hSpCas9	positive selection	3087952
169155545	169155568	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.3716841831021837	[3,3]	[3,3]	6	hSpCas9	positive selection	3087953
169156403	169156426		-	24336571	A375	resistance to PLX after 7 days	AGATTGCCTTCCATTTGCAAAGG	SH3RF1	ENSG00000154447	0.14342359137430022	[8,8]	[9,9]	4	hSpCas9	positive selection	3144031
169156535	169156558		+	24336571	A375	resistance to PLX after 7 days	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.5161295400242832	[3,3]	[6,5]	9	hSpCas9	positive selection	3144032
169155545	169155568		-	24336571	A375	resistance to PLX after 7 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.43879283038353545	[7,4]	[8,9]	9	hSpCas9	positive selection	3144033
169156595	169156618		+	24336571	A375	resistance to PLX after 7 days	TGTCACCTTTGCTGAATTTAAGG	SH3RF1	ENSG00000154447	-0.012204757048393411	[41,39]	[41,38]	0	hSpCas9	positive selection	3144034
169156403	169156426		-	24336571	A375	resistance to PLX after 14 days	AGATTGCCTTCCATTTGCAAAGG	SH3RF1	ENSG00000154447	0.30460871441897736	[7,7]	[3,4]	3	hSpCas9	positive selection	3201824
169156535	169156558		+	24336571	A375	resistance to PLX after 14 days	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.38574539072177616	[4,4]	[1,2]	4	hSpCas9	positive selection	3201825
169155545	169155568		-	24336571	A375	resistance to PLX after 14 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.678224875515959	[9,9]	[7,6]	6	hSpCas9	positive selection	3201826
169156595	169156618		+	24336571	A375	resistance to PLX after 14 days	TGTCACCTTTGCTGAATTTAAGG	SH3RF1	ENSG00000154447	-0.589832779330147	[49,51]	[14,15]	-7	hSpCas9	positive selection	3201827
169156403	169156426		-	24336571	A375	viability after 7 days	AGATTGCCTTCCATTTGCAAAGG	SH3RF1	ENSG00000154447	-0.5975875420222218	[14]	[8,8]	-7	hSpCas9	negative selection	3259617
169156535	169156558		+	24336571	A375	viability after 7 days	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	-0.8522078683116144	[7]	[3,3]	-8	hSpCas9	negative selection	3259618
169155545	169155568		-	24336571	A375	viability after 7 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.6093740669110503	[4]	[7,4]	8	hSpCas9	negative selection	3259619
169156595	169156618		+	24336571	A375	viability after 7 days	TGTCACCTTTGCTGAATTTAAGG	SH3RF1	ENSG00000154447	0.576815509247832	[28]	[41,39]	8	hSpCas9	negative selection	3259620
169156403	169156426		-	24336571	A375	viability after 14 days	AGATTGCCTTCCATTTGCAAAGG	SH3RF1	ENSG00000154447	-0.7665396484352411	[14]	[7,7]	-7	hSpCas9	negative selection	3317410
169156535	169156558		+	24336571	A375	viability after 14 days	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	-0.7051775804536456	[7]	[4,4]	-7	hSpCas9	negative selection	3317411
169155545	169155568		-	24336571	A375	viability after 14 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	1.1814350437961434	[4]	[9,9]	9	hSpCas9	negative selection	3317412
169156595	169156618		+	24336571	A375	viability after 14 days	TGTCACCTTTGCTGAATTTAAGG	SH3RF1	ENSG00000154447	0.9059308880952806	[28]	[49,51]	9	hSpCas9	negative selection	3317413
169156635	169156658	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.2662357446111776	[183,183]	[0,0]	-2	hSpCas9	positive selection	3392279
169156540	169156563	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	0.13838513872232763	[138,138]	[0,0]	0	hSpCas9	positive selection	3392280
169155518	169155541	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.28004628794591846	[125,125]	[0,0]	1	hSpCas9	positive selection	3392281
169136480	169136503	4	-	26780180	HT29	viability (Avana library 4 designs)	CCAAGAAGAACACCAAAAAGCGG	SH3RF1	ENSG00000154447	-0.469114100856329	[]	[]	-7	hSpCas9	negative selection	3458596
169136360	169136383	4	-	26780180	HT29	viability (Avana library 4 designs)	GCAACCCCACTGCTGCTGCACGG	SH3RF1	ENSG00000154447	-0.169072880807387	[]	[]	-3	hSpCas9	negative selection	3458597
169156535	169156558	4	+	26780180	HT29	viability (Avana library 4 designs)	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.0763399064782121	[]	[]	0	hSpCas9	negative selection	3458598
169155545	169155568	4	-	26780180	HT29	viability (Avana library 4 designs)	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.249418925369855	[]	[]	0	hSpCas9	negative selection	3458599
169136360	169136383	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAACCCCACTGCTGCTGCACGG	SH3RF1	ENSG00000154447	4.08371728983752	[]	[]	6	hSpCas9	negative selection	3558113
169156535	169156558	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	-2.55860383455292	[]	[]	-3	hSpCas9	negative selection	3558114
169136480	169136503	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAGAAGAACACCAAAAAGCGG	SH3RF1	ENSG00000154447	-0.748354172980037	[]	[]	-1	hSpCas9	negative selection	3558115
169155545	169155568	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	3.54004701481658	[]	[]	5	hSpCas9	negative selection	3558116
169268989	169269012	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGCTGGTCAGACTTCTGGATGG	SH3RF1	ENSG00000154447	0.519622774304406	[]	[]	0	hSpCas9	negative selection	3558117
169156550	169156573	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGAAAATTGGTACCATGGGG	SH3RF1	ENSG00000154447	1.40301104245829	[]	[]	2	hSpCas9	negative selection	3558118
169136360	169136383	4	-	26780180	A375	viability (Avana lentiGuide)	GCAACCCCACTGCTGCTGCACGG	SH3RF1	ENSG00000154447	-3.80556333676882	[]	[]	-6	hSpCas9	negative selection	3666772
169156535	169156558	4	+	26780180	A375	viability (Avana lentiGuide)	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.719502700762888	[]	[]	0	hSpCas9	negative selection	3666773
169136480	169136503	4	-	26780180	A375	viability (Avana lentiGuide)	CCAAGAAGAACACCAAAAAGCGG	SH3RF1	ENSG00000154447	-5.92187710136213	[]	[]	-8	hSpCas9	negative selection	3666774
169155545	169155568	4	-	26780180	A375	viability (Avana lentiGuide)	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-1.99600708307626	[]	[]	-3	hSpCas9	negative selection	3666775
169268989	169269012	4	-	26780180	A375	viability (Avana lentiGuide)	TTGCTGGTCAGACTTCTGGATGG	SH3RF1	ENSG00000154447	-3.60609974809691	[]	[]	-6	hSpCas9	negative selection	3666776
169156550	169156573	4	-	26780180	A375	viability (Avana lentiGuide)	GGATGAAAATTGGTACCATGGGG	SH3RF1	ENSG00000154447	-1.67898554727083	[]	[]	-3	hSpCas9	negative selection	3666777
169136360	169136383	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAACCCCACTGCTGCTGCACGG	SH3RF1	ENSG00000154447	-0.02638210041830344	[5]	[6,4]	0	hSpCas9	positive selection	3775379
169156535	169156558	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	-0.1957671257789717	[6]	[5,4]	-3	hSpCas9	positive selection	3775380
169136480	169136503	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAGAAGAACACCAAAAAGCGG	SH3RF1	ENSG00000154447	-0.057557146673185525	[5]	[5,4]	-1	hSpCas9	positive selection	3775381
169155545	169155568	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.33519491525136264	[4]	[5,6]	8	hSpCas9	positive selection	3775382
169268989	169269012	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGCTGGTCAGACTTCTGGATGG	SH3RF1	ENSG00000154447	0.11770824293199206	[6]	[6,6]	3	hSpCas9	positive selection	3775383
169156550	169156573	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGAAAATTGGTACCATGGGG	SH3RF1	ENSG00000154447	-0.10169259806291417	[5]	[5,3]	-2	hSpCas9	positive selection	3775384
169136360	169136383	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAACCCCACTGCTGCTGCACGG	SH3RF1	ENSG00000154447	0.31428531107328084	[6]	[7,7]	8	hSpCas9	positive selection	3883986
169156535	169156558	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.05486774937757735	[6]	[6,4]	1	hSpCas9	positive selection	3883987
169136480	169136503	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAGAAGAACACCAAAAAGCGG	SH3RF1	ENSG00000154447	0.4372353793493972	[5]	[6,6]	9	hSpCas9	positive selection	3883988
169155545	169155568	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.20103000247226832	[5]	[4,5]	5	hSpCas9	positive selection	3883989
169268989	169269012	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGCTGGTCAGACTTCTGGATGG	SH3RF1	ENSG00000154447	0.26389233586285	[6]	[7,6]	7	hSpCas9	positive selection	3883990
169156550	169156573	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGAAAATTGGTACCATGGGG	SH3RF1	ENSG00000154447	0.3024261102599656	[5]	[6,5]	8	hSpCas9	positive selection	3883991
169155518	169155541	4	-	26780180	A375	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.890342027725425	[]	[]	4	hSpCas9	negative selection	3994034
169130137	169130160	4	-	26780180	A375	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	1.3698743764508	[]	[]	7	hSpCas9	negative selection	3994035
169130118	169130141	4	+	26780180	A375	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.400333297699735	[]	[]	1	hSpCas9	negative selection	3994036
169155545	169155568	4	-	26780180	A375	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.553397054586931	[]	[]	1	hSpCas9	negative selection	3994037
169156540	169156563	4	-	26780180	A375	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	1.12462933572689	[]	[]	5	hSpCas9	negative selection	3994038
169156635	169156658	4	+	26780180	A375	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	1.13663298245882	[]	[]	6	hSpCas9	negative selection	3994039
169155518	169155541	4	-	26780180	HT29	viability (GeCKOv2 library)	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	1.65366293585746	[]	[]	8	hSpCas9	negative selection	4102000
169130137	169130160	4	-	26780180	HT29	viability (GeCKOv2 library)	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.982720604781584	[]	[]	4	hSpCas9	negative selection	4102001
169130118	169130141	4	+	26780180	HT29	viability (GeCKOv2 library)	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.757481237786339	[]	[]	3	hSpCas9	negative selection	4102002
169155545	169155568	4	-	26780180	HT29	viability (GeCKOv2 library)	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.0667761682188069	[]	[]	0	hSpCas9	negative selection	4102003
169156540	169156563	4	-	26780180	HT29	viability (GeCKOv2 library)	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	0.672156199037415	[]	[]	2	hSpCas9	negative selection	4102004
169156635	169156658	4	+	26780180	HT29	viability (GeCKOv2 library)	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	1.3183183233436	[]	[]	6	hSpCas9	negative selection	4102005
169156403	169156426	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGATTGCCTTCCATTTGCAAAGG	SH3RF1	ENSG00000154447	-0.1649435731737177	[3]	[1,1]	-4	hSpCas9	positive selection	4169962
169156535	169156558	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	-0.19661635331855054	[2]	[1,1]	-5	hSpCas9	positive selection	4169963
169155545	169155568	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	1.1479508640863294	[3]	[7,2]	9	hSpCas9	positive selection	4169964
169156595	169156618	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTCACCTTTGCTGAATTTAAGG	SH3RF1	ENSG00000154447	0.18008438794093584	[4]	[3,3]	4	hSpCas9	positive selection	4169965
169156403	169156426	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGATTGCCTTCCATTTGCAAAGG	SH3RF1	ENSG00000154447	1.3377243581102753	[3]	[0,1,3,6]	9	hSpCas9	positive selection	4233984
169156535	169156558	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.6474905290327002	[2]	[0,1,4,0]	4	hSpCas9	positive selection	4233985
169155545	169155568	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.17219575548268895	[1]	[0,0,0,0]	-2	hSpCas9	positive selection	4233986
169156595	169156618	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTCACCTTTGCTGAATTTAAGG	SH3RF1	ENSG00000154447	0.9664974833702111	[5]	[5,3,4,4]	6	hSpCas9	positive selection	4233987
169155545	169155568	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.29026878352810653	[2]	[2,1]	6	hSpCas9	positive selection	4297600
169130118	169130141	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.22502508648100936	[3]	[3,2]	4	hSpCas9	positive selection	4297601
169130137	169130160	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.06731219231120987	[3]	[2,2]	-1	hSpCas9	positive selection	4297602
169156635	169156658	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.2684998674285379	[3]	[3,2]	5	hSpCas9	positive selection	4361854
169156540	169156563	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.2324749053055482	[2]	[2,0]	-5	hSpCas9	positive selection	4361855
169155518	169155541	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.6005597983276331	[2]	[1,0]	-8	hSpCas9	positive selection	4361856
169268807	169268829	4	+	27760321	OCIAML3	viability	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	0.15426911185601822	[1258,1019]	[824,1196]	1	hSpCas9	negative selection	4438710
169122117	169122139	4	+	27760321	OCIAML3	viability	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	-0.5166426233066136	[494,388]	[213,273]	-5	hSpCas9	negative selection	4438711
169130087	169130109	4	+	27760321	OCIAML3	viability	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	0.6073824762443398	[494,404]	[266,880]	7	hSpCas9	negative selection	4438712
169130122	169130144	4	+	27760321	OCIAML3	viability	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	-0.40928471189138105	[335,254]	[189,149]	-4	hSpCas9	negative selection	4438713
169136445	169136467	4	+	27760321	OCIAML3	viability	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.31411347823905	[501,499]	[270,374]	-3	hSpCas9	negative selection	4438714
169268807	169268829	4	+	27760321	OCIAML2	viability	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	-0.288772629499942	[1258,1019]	[624,915]	-4	hSpCas9	negative selection	4522173
169122117	169122139	4	+	27760321	OCIAML2	viability	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	-0.2811518728812427	[494,388]	[224,380]	-3	hSpCas9	negative selection	4522174
169130087	169130109	4	+	27760321	OCIAML2	viability	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	0.9282508726818496	[494,404]	[536,889]	9	hSpCas9	negative selection	4522175
169130122	169130144	4	+	27760321	OCIAML2	viability	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.41034750971392175	[335,254]	[290,346]	5	hSpCas9	negative selection	4522176
169136445	169136467	4	+	27760321	OCIAML2	viability	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.4381781337366082	[501,499]	[407,738]	6	hSpCas9	negative selection	4522177
169268807	169268829	4	+	27760321	MV411	viability	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	-0.48776727909478723	[1258,1019]	[275,919]	-3	hSpCas9	negative selection	4605636
169122117	169122139	4	+	27760321	MV411	viability	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	0.2988367755324579	[494,388]	[178,622]	2	hSpCas9	negative selection	4605637
169130087	169130109	4	+	27760321	MV411	viability	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	-0.2783428236133178	[494,404]	[56,523]	-2	hSpCas9	negative selection	4605638
169130122	169130144	4	+	27760321	MV411	viability	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.9104921267929391	[335,254]	[146,688]	6	hSpCas9	negative selection	4605639
169136445	169136467	4	+	27760321	MV411	viability	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.46533653977713074	[501,499]	[250,223]	-3	hSpCas9	negative selection	4605640
169268807	169268829	4	+	27760321	HL60	viability	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	-0.40234295586833524	[1258,1019]	[701,698]	-4	hSpCas9	negative selection	4689099
169122117	169122139	4	+	27760321	HL60	viability	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	-0.06948935749528756	[494,388]	[335,347]	-1	hSpCas9	negative selection	4689100
169130087	169130109	4	+	27760321	HL60	viability	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	-0.4346628744747791	[494,404]	[274,265]	-5	hSpCas9	negative selection	4689101
169130122	169130144	4	+	27760321	HL60	viability	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.6519011264761229	[335,254]	[334,419]	7	hSpCas9	negative selection	4689102
169136445	169136467	4	+	27760321	HL60	viability	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.050321240097289444	[501,499]	[411,438]	0	hSpCas9	negative selection	4689103
169268807	169268829	4	+	27760321	HT1080	viability	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	-1.1464221762864337	[1019,795]	[192,130]	-4	hSpCas9	negative selection	4772562
169122117	169122139	4	+	27760321	HT1080	viability	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	2.8322350570143393	[388,303]	[711,1279]	9	hSpCas9	negative selection	4772563
169130087	169130109	4	+	27760321	HT1080	viability	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	-1.2292730835368935	[404,315]	[34,89]	-5	hSpCas9	negative selection	4772564
169130122	169130144	4	+	27760321	HT1080	viability	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.7042964009341198	[254,198]	[143,150]	4	hSpCas9	negative selection	4772565
169136445	169136467	4	+	27760321	HT1080	viability	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.766840484281262	[499,389]	[107,99]	-3	hSpCas9	negative selection	4772566
169268807	169268829	4	+	27760321	HT29	viability after 7 days	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	0.12898954500875415	[1019,795]	[1729,1247,925]	2	hSpCas9	negative selection	4856025
169122117	169122139	4	+	27760321	HT29	viability after 7 days	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	-0.28819649981729833	[388,303]	[296,346,437]	-4	hSpCas9	negative selection	4856026
169130087	169130109	4	+	27760321	HT29	viability after 7 days	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	0.2402728981668679	[404,315]	[613,516,520]	3	hSpCas9	negative selection	4856027
169130122	169130144	4	+	27760321	HT29	viability after 7 days	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.5826059652956058	[254,198]	[455,506,352]	8	hSpCas9	negative selection	4856028
169136445	169136467	4	+	27760321	HT29	viability after 7 days	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.20029638768322655	[499,389]	[499,544,449]	-3	hSpCas9	negative selection	4856029
169268807	169268829	4	+	27760321	HT29	viability after 25 days	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	0.6254983493795772	[1019,795]	[1300,1960,1551]	7	hSpCas9	negative selection	4939488
169122117	169122139	4	+	27760321	HT29	viability after 25 days	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	0.3233004107002841	[388,303]	[517,464,501]	3	hSpCas9	negative selection	4939489
169130087	169130109	4	+	27760321	HT29	viability after 25 days	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	0.806104316281067	[404,315]	[803,704,636]	8	hSpCas9	negative selection	4939490
169130122	169130144	4	+	27760321	HT29	viability after 25 days	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.17774297542669232	[254,198]	[176,426,281]	1	hSpCas9	negative selection	4939491
169136445	169136467	4	+	27760321	HT29	viability after 25 days	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.037699520226665006	[499,389]	[522,486,558]	0	hSpCas9	negative selection	4939492
169268807	169268829	4	+	27760321	HT29	viability after 22 days	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	0.5057693905897582	[1019,795]	[1213,1533,1732]	5	hSpCas9	negative selection	5022951
169122117	169122139	4	+	27760321	HT29	viability after 22 days	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	0.2829809586754415	[388,303]	[461,504,495]	3	hSpCas9	negative selection	5022952
169130087	169130109	4	+	27760321	HT29	viability after 22 days	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	0.7305811220652129	[404,315]	[638,633,803]	8	hSpCas9	negative selection	5022953
169130122	169130144	4	+	27760321	HT29	viability after 22 days	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.5628350800035384	[254,198]	[470,474,212]	6	hSpCas9	negative selection	5022954
169136445	169136467	4	+	27760321	HT29	viability after 22 days	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.13853778656611865	[499,389]	[441,604,655]	1	hSpCas9	negative selection	5022955
169268807	169268829	4	+	27760321	HT29	viability after 19 days	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	0.6230643319348155	[1019,795]	[1875,1699,1262]	6	hSpCas9	negative selection	5106414
169122117	169122139	4	+	27760321	HT29	viability after 19 days	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	0.777209216534198	[388,303]	[272,890,824]	7	hSpCas9	negative selection	5106415
169130087	169130109	4	+	27760321	HT29	viability after 19 days	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	0.8185708225009194	[404,315]	[469,822,855]	8	hSpCas9	negative selection	5106416
169130122	169130144	4	+	27760321	HT29	viability after 19 days	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.16640368477196082	[254,198]	[324,223,326]	1	hSpCas9	negative selection	5106417
169136445	169136467	4	+	27760321	HT29	viability after 19 days	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.09776474099685786	[499,389]	[466,415,539]	-1	hSpCas9	negative selection	5106418
169268807	169268829	4	+	27760321	HT29	viability after 16 days	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	0.6708561021819619	[1019,795]	[1895,1613,1367]	7	hSpCas9	negative selection	5189877
169122117	169122139	4	+	27760321	HT29	viability after 16 days	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	0.20754423027220106	[388,303]	[536,271,546]	2	hSpCas9	negative selection	5189878
169130087	169130109	4	+	27760321	HT29	viability after 16 days	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	1.1424917700276367	[404,315]	[860,1013,789]	9	hSpCas9	negative selection	5189879
169130122	169130144	4	+	27760321	HT29	viability after 16 days	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.2316345666375757	[254,198]	[168,387,322]	2	hSpCas9	negative selection	5189880
169136445	169136467	4	+	27760321	HT29	viability after 16 days	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.08478881332037058	[499,389]	[582,505,328]	-1	hSpCas9	negative selection	5189881
169268807	169268829	4	+	27760321	HT29	viability after 13 days	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	0.26272652244804884	[1019,795]	[940,1265,1565]	3	hSpCas9	negative selection	5273340
169122117	169122139	4	+	27760321	HT29	viability after 13 days	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	0.1101093703759032	[388,303]	[502,288,504]	1	hSpCas9	negative selection	5273341
169130087	169130109	4	+	27760321	HT29	viability after 13 days	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	0.505113991021948	[404,315]	[608,603,568]	6	hSpCas9	negative selection	5273342
169130122	169130144	4	+	27760321	HT29	viability after 13 days	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.3336724175736269	[254,198]	[501,226,269]	4	hSpCas9	negative selection	5273343
169136445	169136467	4	+	27760321	HT29	viability after 13 days	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.4357291028671028	[499,389]	[796,711,591]	5	hSpCas9	negative selection	5273344
169268807	169268829	4	+	27760321	HT29	viability after 10 days	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	0.32233375426716915	[1019,795]	[1352,1440,1457]	4	hSpCas9	negative selection	5356803
169122117	169122139	4	+	27760321	HT29	viability after 10 days	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	-0.14651459618794396	[388,303]	[320,530,325]	-2	hSpCas9	negative selection	5356804
169130087	169130109	4	+	27760321	HT29	viability after 10 days	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	0.3821272850617978	[404,315]	[549,468,733]	5	hSpCas9	negative selection	5356805
169130122	169130144	4	+	27760321	HT29	viability after 10 days	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.006921858065898512	[254,198]	[301,270,280]	0	hSpCas9	negative selection	5356806
169136445	169136467	4	+	27760321	HT29	viability after 10 days	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.13684537780602346	[499,389]	[578,554,694]	1	hSpCas9	negative selection	5356807
169268807	169268829	4	+	27760321	MOLM13	viability	GTAGGCTACTTACCCTCACTGG	SH3RF1	ENSG00000154447	0.06483320304705131	[1258,1019]	[636,695]	0	hSpCas9	negative selection	5440266
169122117	169122139	4	+	27760321	MOLM13	viability	CGGCCGTAAATGTGCAATCTGG	SH3RF1	ENSG00000154447	0.021107519407365716	[494,388]	[420,106]	0	hSpCas9	negative selection	5440267
169130087	169130109	4	+	27760321	MOLM13	viability	ACGAGGGGCCAGTTGTCACTGG	SH3RF1	ENSG00000154447	1.2863238947774471	[494,404]	[626,606]	8	hSpCas9	negative selection	5440268
169130122	169130144	4	+	27760321	MOLM13	viability	GGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.11462621149672725	[335,254]	[352,30]	0	hSpCas9	negative selection	5440269
169136445	169136467	4	+	27760321	MOLM13	viability	GACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.5169869308910928	[501,499]	[101,279]	-3	hSpCas9	negative selection	5440270
169270740	169270763	4	+	27661255	K562	viability	GGGAGAGAGAGACCGACCCAGGG	SH3RF1	ENSG00000154447	0.017874525524826157	[1222,1307]	[1187,880]	0	dCas9-KRAB	negative selection	5510836
169270698	169270721	4	-	27661255	K562	viability	GGGCCGGGAATCAGGACCTGCGG	SH3RF1	ENSG00000154447	0.042142066220488515	[715,812]	[588,659]	1	dCas9-KRAB	negative selection	5510837
169155545	169155568	4	-	27260156	BXPC3	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.3449516147629108	[246]	[271,305,401,339]	7	hSpCas9	negative selection	5570060
169130118	169130141	4	+	27260156	BXPC3	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.3235721936169692	[493]	[609,612,645,727]	7	hSpCas9	negative selection	5570061
169130137	169130160	4	-	27260156	BXPC3	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.07193338603380472	[645]	[613,698,701,847]	1	hSpCas9	negative selection	5570062
169156635	169156658	4	+	27260156	BXPC3	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.1582461434881233	[539]	[474,515,716,861]	3	hSpCas9	negative selection	5634314
169156540	169156563	4	-	27260156	BXPC3	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.21997935229618504	[437]	[283,441,388,473]	-5	hSpCas9	negative selection	5634315
169155518	169155541	4	-	27260156	BXPC3	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.19371800657720317	[276]	[313,289,343,385]	4	hSpCas9	negative selection	5634316
169155545	169155568	4	-	27260156	A673	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.41504955574369573	[246]	[483,365,352,388]	8	hSpCas9	negative selection	5691311
169130118	169130141	4	+	27260156	A673	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.4182204015572064	[493]	[854,682,781,862]	8	hSpCas9	negative selection	5691312
169130137	169130160	4	-	27260156	A673	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.05645764242832063	[645]	[1011,733,734,767]	1	hSpCas9	negative selection	5691313
169156635	169156658	4	+	27260156	A673	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.20141139598226296	[539]	[613,613,523,503]	-5	hSpCas9	negative selection	5755565
169156540	169156563	4	-	27260156	A673	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.1580401356657325	[437]	[477,495,495,410]	-4	hSpCas9	negative selection	5755566
169155518	169155541	4	-	27260156	A673	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.14234114705153944	[276]	[267,273,330,329]	-4	hSpCas9	negative selection	5755567
169155545	169155568	4	-	27260156	A375	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.3071349288134464	[246]	[462,326,340,298]	4	hSpCas9	negative selection	5812562
169130118	169130141	4	+	27260156	A375	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.5459247692565564	[493]	[789,1200,769,674]	7	hSpCas9	negative selection	5812563
169130137	169130160	4	-	27260156	A375	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.21775179003928719	[645]	[646,745,626,592]	-3	hSpCas9	negative selection	5812564
169156635	169156658	4	+	27260156	A375	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.0672890202878301	[539]	[458,738,706,735]	1	hSpCas9	negative selection	5876816
169156540	169156563	4	-	27260156	A375	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	0.1625400355324365	[437]	[517,550,654,561]	2	hSpCas9	negative selection	5876817
169155518	169155541	4	-	27260156	A375	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.39878263269137393	[276]	[386,546,526,277]	6	hSpCas9	negative selection	5876818
169155545	169155568	4	-	27260156	COLO741	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.45794511608093896	[246]	[542,365,401]	8	hSpCas9	negative selection	5933813
169130118	169130141	4	+	27260156	COLO741	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.47204542229276314	[493]	[723,872,1004]	8	hSpCas9	negative selection	5933814
169130137	169130160	4	-	27260156	COLO741	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.15279502976870052	[645]	[931,665,1136]	3	hSpCas9	negative selection	5933815
169156635	169156658	4	+	27260156	COLO741	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.27902597480782737	[539]	[637,470,598]	-5	hSpCas9	negative selection	5998067
169156540	169156563	4	-	27260156	COLO741	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.4185736763748081	[437]	[555,423,295]	-7	hSpCas9	negative selection	5998068
169155518	169155541	4	-	27260156	COLO741	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.03645584268080726	[276]	[444,315,335]	0	hSpCas9	negative selection	5998069
169155545	169155568	4	-	27260156	CAL120	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.011426085540949704	[246]	[405,240,296]	0	hSpCas9	negative selection	6055064
169130118	169130141	4	+	27260156	CAL120	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.3723946101328928	[493]	[873,687,835]	5	hSpCas9	negative selection	6055065
169130137	169130160	4	-	27260156	CAL120	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.4476440924680838	[645]	[971,1042,1251]	6	hSpCas9	negative selection	6055066
169156635	169156658	4	+	27260156	CAL120	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-1.22658203706255	[539]	[314,233,315]	-9	hSpCas9	negative selection	6119318
169156540	169156563	4	-	27260156	CAL120	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.5070543224411765	[437]	[408,459,286]	-6	hSpCas9	negative selection	6119319
169155518	169155541	4	-	27260156	CAL120	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.39286263518337483	[276]	[537,188,639]	6	hSpCas9	negative selection	6119320
169155545	169155568	4	-	27260156	CADOES1	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.6687341064741947	[246]	[351,445,245,418]	9	hSpCas9	negative selection	6176315
169130118	169130141	4	+	27260156	CADOES1	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.3807767273498447	[493]	[633,736,477,541]	6	hSpCas9	negative selection	6176316
169130137	169130160	4	-	27260156	CADOES1	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.1511463233756114	[645]	[559,493,519,591]	-3	hSpCas9	negative selection	6176317
169156635	169156658	4	+	27260156	CADOES1	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.2745245920963093	[539]	[372,384,381,524]	-5	hSpCas9	negative selection	6240569
169156540	169156563	4	-	27260156	CADOES1	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	0.31838725792624795	[437]	[416,701,468,441]	5	hSpCas9	negative selection	6240570
169155518	169155541	4	-	27260156	CADOES1	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.032641795169995436	[276]	[178,337,259,277]	0	hSpCas9	negative selection	6240571
169155545	169155568	4	-	27260156	EWS502	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.41418451057094774	[246]	[316,276,416,392]	7	hSpCas9	negative selection	6297566
169130118	169130141	4	+	27260156	EWS502	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.3552486102065912	[493]	[652,546,760,725]	6	hSpCas9	negative selection	6297567
169130137	169130160	4	-	27260156	EWS502	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.02642979450619226	[645]	[654,495,610,950]	0	hSpCas9	negative selection	6297568
169156635	169156658	4	+	27260156	EWS502	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.11607736652084014	[539]	[575,528,716,668]	2	hSpCas9	negative selection	6361820
169156540	169156563	4	-	27260156	EWS502	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	0.13666314216561867	[437]	[485,631,447,465]	2	hSpCas9	negative selection	6361821
169155518	169155541	4	-	27260156	EWS502	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.3513467327197368	[276]	[295,414,437,353]	6	hSpCas9	negative selection	6361822
169155545	169155568	4	-	27260156	EW8	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.563170564094434	[246]	[311,257,365,235]	8	hSpCas9	negative selection	6418817
169130118	169130141	4	+	27260156	EW8	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.5185619902499382	[493]	[759,510,560,482]	8	hSpCas9	negative selection	6418818
169130137	169130160	4	-	27260156	EW8	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.4904788606400199	[645]	[495,478,259,287]	-7	hSpCas9	negative selection	6418819
169156635	169156658	4	+	27260156	EW8	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.3147738446379533	[539]	[494,312,334,281]	-5	hSpCas9	negative selection	6483071
169156540	169156563	4	-	27260156	EW8	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	0.05235947586201384	[437]	[484,566,217,240]	0	hSpCas9	negative selection	6483072
169155518	169155541	4	-	27260156	EW8	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.28535831576596493	[276]	[203,137,310,63]	-5	hSpCas9	negative selection	6483073
169155545	169155568	4	-	27260156	CORL105	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.1361706847703682	[246]	[356,249,382,293]	2	hSpCas9	negative selection	6540068
169130118	169130141	4	+	27260156	CORL105	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.5061200092835431	[493]	[805,801,978,722]	8	hSpCas9	negative selection	6540069
169130137	169130160	4	-	27260156	CORL105	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.17900927828015173	[645]	[562,670,875,590]	-3	hSpCas9	negative selection	6540070
169156635	169156658	4	+	27260156	CORL105	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.07334882122395633	[539]	[511,623,579,679]	-1	hSpCas9	negative selection	6604322
169156540	169156563	4	-	27260156	CORL105	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.24236201028365012	[437]	[415,448,490,385]	-4	hSpCas9	negative selection	6604323
169155518	169155541	4	-	27260156	CORL105	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.07909649836756438	[276]	[256,327,315,325]	-1	hSpCas9	negative selection	6604324
169155545	169155568	4	-	27260156	HS294T	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.19591513924723192	[246]	[85,82,108,172]	2	hSpCas9	negative selection	6661319
169130118	169130141	4	+	27260156	HS294T	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	-0.017486598700735205	[493]	[127,197,198,243]	0	hSpCas9	negative selection	6661320
169130137	169130160	4	-	27260156	HS294T	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.05036472042526485	[645]	[172,249,272,280]	0	hSpCas9	negative selection	6661321
169156635	169156658	4	+	27260156	HS294T	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.10150009638397031	[539]	[155,153,311,293]	1	hSpCas9	negative selection	6725573
169156540	169156563	4	-	27260156	HS294T	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.4749976724216694	[437]	[77,119,167,125]	-6	hSpCas9	negative selection	6725574
169155518	169155541	4	-	27260156	HS294T	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.7387114992987911	[276]	[58,63,64,69]	-8	hSpCas9	negative selection	6725575
169155545	169155568	4	-	27260156	HCC44	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.2863452050509925	[246]	[399,325,341,300]	4	hSpCas9	negative selection	6782570
169130118	169130141	4	+	27260156	HCC44	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.3065003199785588	[493]	[625,688,797,658]	5	hSpCas9	negative selection	6782571
169130137	169130160	4	-	27260156	HCC44	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.11212250044791694	[645]	[837,788,983,585]	1	hSpCas9	negative selection	6782572
169156635	169156658	4	+	27260156	HCC44	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.17728483222196814	[539]	[812,528,681,762]	3	hSpCas9	negative selection	6846824
169156540	169156563	4	-	27260156	HCC44	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.32581275088504486	[437]	[600,149,577,335]	-5	hSpCas9	negative selection	6846825
169155518	169155541	4	-	27260156	HCC44	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.08016650154180616	[276]	[310,206,557,301]	1	hSpCas9	negative selection	6846826
169155545	169155568	4	-	27260156	G402	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.302103126764266	[246]	[151,320,166,323]	-4	hSpCas9	negative selection	6903821
169130118	169130141	4	+	27260156	G402	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.6931175040658653	[493]	[1073,1156,895,800]	8	hSpCas9	negative selection	6903822
169130137	169130160	4	-	27260156	G402	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.10924298164877316	[645]	[521,943,610,820]	-1	hSpCas9	negative selection	6903823
169156635	169156658	4	+	27260156	G402	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.10517586391510472	[539]	[1065,687,470,659]	1	hSpCas9	negative selection	6968075
169156540	169156563	4	-	27260156	G402	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	0.11247018948798812	[437]	[860,568,674,259]	1	hSpCas9	negative selection	6968076
169155518	169155541	4	-	27260156	G402	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.5208878671382784	[276]	[240,202,170,320]	-6	hSpCas9	negative selection	6968077
169155545	169155568	4	-	27260156	L33	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.40489835942500885	[246]	[309,114,234,343]	8	hSpCas9	negative selection	7025072
169130118	169130141	4	+	27260156	L33	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.3358553357035732	[493]	[665,254,365,621]	7	hSpCas9	negative selection	7025073
169130137	169130160	4	-	27260156	L33	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.04812751491916967	[645]	[570,291,457,661]	1	hSpCas9	negative selection	7025074
169156635	169156658	4	+	27260156	L33	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.07636673620732234	[539]	[455,234,360,446]	-2	hSpCas9	negative selection	7089326
169156540	169156563	4	-	27260156	L33	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.31872837513277336	[437]	[433,136,217,287]	-6	hSpCas9	negative selection	7089327
169155518	169155541	4	-	27260156	L33	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.2611540850559533	[276]	[242,76,90,346]	-6	hSpCas9	negative selection	7089328
169155545	169155568	4	-	27260156	K562	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.44907826762800696	[246]	[131,155,199,151]	-5	hSpCas9	negative selection	7146323
169130118	169130141	4	+	27260156	K562	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.48918512146822346	[493]	[667,771,516,524]	6	hSpCas9	negative selection	7146324
169130137	169130160	4	-	27260156	K562	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.32699458913226975	[645]	[1109,760,641,428]	4	hSpCas9	negative selection	7146325
169156635	169156658	4	+	27260156	K562	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.10057535230969453	[539]	[733,424,568,356]	1	hSpCas9	negative selection	7210577
169156540	169156563	4	-	27260156	K562	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.06570489643972643	[437]	[494,340,421,248]	-1	hSpCas9	negative selection	7210578
169155518	169155541	4	-	27260156	K562	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.413620736671904	[276]	[394,208,520,197]	5	hSpCas9	negative selection	7210579
169155545	169155568	4	-	27260156	HT29	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.4044564422292717	[246]	[510,314,441,328]	7	hSpCas9	negative selection	7267574
169130118	169130141	4	+	27260156	HT29	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.5241856666460935	[493]	[873,829,895,847]	8	hSpCas9	negative selection	7267575
169130137	169130160	4	-	27260156	HT29	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.17157387581758354	[645]	[867,844,886,921]	3	hSpCas9	negative selection	7267576
169156635	169156658	4	+	27260156	HT29	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.2817222265842957	[539]	[703,859,909,719]	5	hSpCas9	negative selection	7331828
169156540	169156563	4	-	27260156	HT29	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	0.24554558389090111	[437]	[651,863,664,390]	5	hSpCas9	negative selection	7331829
169155518	169155541	4	-	27260156	HT29	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.2792716531808417	[276]	[242,301,362,207]	-5	hSpCas9	negative selection	7331830
169155545	169155568	4	-	27260156	MHHES1	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.4634977171863316	[246]	[437,404,485,239]	7	hSpCas9	negative selection	7388825
169130118	169130141	4	+	27260156	MHHES1	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.25924503328882204	[493]	[721,490,542,838]	5	hSpCas9	negative selection	7388826
169130137	169130160	4	-	27260156	MHHES1	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.05377580611518107	[645]	[1005,803,928,387]	1	hSpCas9	negative selection	7388827
169156635	169156658	4	+	27260156	MHHES1	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.21575819205460695	[539]	[563,609,577,378]	-4	hSpCas9	negative selection	7453079
169156540	169156563	4	-	27260156	MHHES1	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.3860305287359853	[437]	[363,560,355,263]	-6	hSpCas9	negative selection	7453080
169155518	169155541	4	-	27260156	MHHES1	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.38412220951097464	[276]	[335,283,111,234]	-6	hSpCas9	negative selection	7453081
169155545	169155568	4	-	27260156	MEWO	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.14114778081090318	[246]	[241,246,272]	3	hSpCas9	negative selection	7510076
169130118	169130141	4	+	27260156	MEWO	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.31150221146794616	[493]	[669,615,452]	6	hSpCas9	negative selection	7510077
169130137	169130160	4	-	27260156	MEWO	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.18537351906850086	[645]	[843,673,573]	4	hSpCas9	negative selection	7510078
169156635	169156658	4	+	27260156	MEWO	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.18858768895519876	[539]	[500,437,401]	-4	hSpCas9	negative selection	7574330
169156540	169156563	4	-	27260156	MEWO	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.1835949443265102	[437]	[449,284,364]	-4	hSpCas9	negative selection	7574331
169155518	169155541	4	-	27260156	MEWO	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.25583022176179426	[276]	[301,120,244]	-5	hSpCas9	negative selection	7574332
169155545	169155568	4	-	27260156	LNCAPCLONEFGC	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.44724251028220363	[246]	[323,322,321,251]	7	hSpCas9	negative selection	7631327
169130118	169130141	4	+	27260156	LNCAPCLONEFGC	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.5168831824337031	[493]	[815,497,614,633]	7	hSpCas9	negative selection	7631328
169130137	169130160	4	-	27260156	LNCAPCLONEFGC	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.18212021540202622	[645]	[408,459,720,508]	-3	hSpCas9	negative selection	7631329
169156635	169156658	4	+	27260156	LNCAPCLONEFGC	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.017884987331709734	[539]	[517,470,549,450]	0	hSpCas9	negative selection	7695581
169156540	169156563	4	-	27260156	LNCAPCLONEFGC	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.33566629172311896	[437]	[248,266,281,458]	-5	hSpCas9	negative selection	7695582
169155518	169155541	4	-	27260156	LNCAPCLONEFGC	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.15033450862134257	[276]	[287,368,267,180]	2	hSpCas9	negative selection	7695583
169155545	169155568	4	-	27260156	PANC0327	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.7399608872504744	[246]	[344,284,214,628]	9	hSpCas9	negative selection	7752578
169130118	169130141	4	+	27260156	PANC0327	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.8792958502485646	[493]	[759,767,926,774]	9	hSpCas9	negative selection	7752579
169130137	169130160	4	-	27260156	PANC0327	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.004275296367361403	[645]	[709,491,530,576]	0	hSpCas9	negative selection	7752580
169156635	169156658	4	+	27260156	PANC0327	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.18611167024640615	[539]	[517,383,864,434]	2	hSpCas9	negative selection	7816832
169156540	169156563	4	-	27260156	PANC0327	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.24219355028793738	[437]	[371,461,251,215]	-4	hSpCas9	negative selection	7816833
169155518	169155541	4	-	27260156	PANC0327	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.7113085937866527	[276]	[310,465,537,280]	8	hSpCas9	negative selection	7816834
169155545	169155568	4	-	27260156	NCIH2009	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.4379141079319223	[246]	[454,422,521]	6	hSpCas9	negative selection	7873829
169130118	169130141	4	+	27260156	NCIH2009	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.7931570258445388	[493]	[1038,1414,1096]	9	hSpCas9	negative selection	7873830
169130137	169130160	4	-	27260156	NCIH2009	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.38354309463081726	[645]	[722,667,689]	-5	hSpCas9	negative selection	7873831
169156635	169156658	4	+	27260156	NCIH2009	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.5864524842451596	[539]	[572,582,362]	-6	hSpCas9	negative selection	7938083
169156540	169156563	4	-	27260156	NCIH2009	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.16301066434328387	[437]	[714,495,461]	-2	hSpCas9	negative selection	7938084
169155518	169155541	4	-	27260156	NCIH2009	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.4060918879972637	[276]	[305,316,254]	-5	hSpCas9	negative selection	7938085
169155545	169155568	4	-	27260156	NCIH1373	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.050607144333709164	[246]	[174,154,478,65]	0	hSpCas9	negative selection	7995080
169130118	169130141	4	+	27260156	NCIH1373	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.5823940281117967	[493]	[974,616,751,269]	6	hSpCas9	negative selection	7995081
169130137	169130160	4	-	27260156	NCIH1373	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.2157967743399284	[645]	[543,939,1036,202]	2	hSpCas9	negative selection	7995082
169156635	169156658	4	+	27260156	NCIH1373	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.47438608648004255	[539]	[249,389,665,105]	-5	hSpCas9	negative selection	8059334
169156540	169156563	4	-	27260156	NCIH1373	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.2804090658919544	[437]	[269,333,526,123]	-3	hSpCas9	negative selection	8059335
169155518	169155541	4	-	27260156	NCIH1373	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.060200487959737314	[276]	[603,191,158,77]	0	hSpCas9	negative selection	8059336
169155545	169155568	4	-	27260156	PATU8902	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.8433152010332751	[246]	[412,596,548,966]	8	hSpCas9	negative selection	8116331
169130118	169130141	4	+	27260156	PATU8902	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.5653750665402644	[493]	[1467,1317,459,949]	6	hSpCas9	negative selection	8116332
169130137	169130160	4	-	27260156	PATU8902	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.09051219625313434	[645]	[1181,1283,565,882]	0	hSpCas9	negative selection	8116333
169156635	169156658	4	+	27260156	PATU8902	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.018210623416370364	[539]	[687,1289,221,923]	0	hSpCas9	negative selection	8180585
169156540	169156563	4	-	27260156	PATU8902	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.7810197173933051	[437]	[202,232,284,764]	-6	hSpCas9	negative selection	8180586
169155518	169155541	4	-	27260156	PATU8902	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.6015537997730722	[276]	[414,208,108,325]	-5	hSpCas9	negative selection	8180587
169155545	169155568	4	-	27260156	PANC1	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.775031471677363	[246]	[523,280,469,181]	9	hSpCas9	negative selection	8237582
169130118	169130141	4	+	27260156	PANC1	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.23372985147488234	[493]	[538,595,514,376]	4	hSpCas9	negative selection	8237583
169130137	169130160	4	-	27260156	PANC1	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.30964920262175877	[645]	[597,893,795,523]	5	hSpCas9	negative selection	8237584
169156635	169156658	4	+	27260156	PANC1	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.2669601259107264	[539]	[519,733,631,400]	4	hSpCas9	negative selection	8301836
169156540	169156563	4	-	27260156	PANC1	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.16822989385613552	[437]	[259,367,429,291]	-3	hSpCas9	negative selection	8301837
169155518	169155541	4	-	27260156	PANC1	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.1254640724201732	[276]	[236,277,126,234]	-2	hSpCas9	negative selection	8301838
169155545	169155568	4	-	27260156	PANC0813	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.7687950469191074	[246]	[444,563,436,523]	9	hSpCas9	negative selection	8358833
169130118	169130141	4	+	27260156	PANC0813	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.7604934001458248	[493]	[1605,858,709,820]	9	hSpCas9	negative selection	8358834
169130137	169130160	4	-	27260156	PANC0813	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.0030746671472426934	[645]	[846,486,1064,656]	0	hSpCas9	negative selection	8358835
169156635	169156658	4	+	27260156	PANC0813	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.46049541392497373	[539]	[496,385,421,536]	-6	hSpCas9	negative selection	8423087
169156540	169156563	4	-	27260156	PANC0813	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	0.0431540786721527	[437]	[632,533,523,442]	0	hSpCas9	negative selection	8423088
169155518	169155541	4	-	27260156	PANC0813	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.1734306774501786	[276]	[400,369,256,143]	-3	hSpCas9	negative selection	8423089
169155545	169155568	4	-	27260156	RDES	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.13063637378415194	[246]	[232,271,383,379]	2	hSpCas9	negative selection	8480084
169130118	169130141	4	+	27260156	RDES	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.4890526441139459	[493]	[688,697,736,1120]	7	hSpCas9	negative selection	8480085
169130137	169130160	4	-	27260156	RDES	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.1021287944106391	[645]	[496,813,686,795]	-2	hSpCas9	negative selection	8480086
169156635	169156658	4	+	27260156	RDES	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.16373564198002227	[539]	[374,500,750,639]	-3	hSpCas9	negative selection	8544338
169156540	169156563	4	-	27260156	RDES	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.08410584660519901	[437]	[361,471,536,554]	-1	hSpCas9	negative selection	8544339
169155518	169155541	4	-	27260156	RDES	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.1422959520300353	[276]	[278,311,368,474]	2	hSpCas9	negative selection	8544340
169155545	169155568	4	-	27260156	PC3	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.37218250434299294	[246]	[236,356,425,291]	7	hSpCas9	negative selection	8601335
169130118	169130141	4	+	27260156	PC3	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.5360762025646052	[493]	[426,673,1218,797]	9	hSpCas9	negative selection	8601336
169130137	169130160	4	-	27260156	PC3	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.09158170043545705	[645]	[401,665,809,642]	-2	hSpCas9	negative selection	8601337
169156635	169156658	4	+	27260156	PC3	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.2984696185810536	[539]	[208,563,682,448]	-6	hSpCas9	negative selection	8665589
169156540	169156563	4	-	27260156	PC3	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.36601552373082175	[437]	[255,278,673,274]	-7	hSpCas9	negative selection	8665590
169155518	169155541	4	-	27260156	PC3	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.1674775894138758	[276]	[198,217,603,359]	4	hSpCas9	negative selection	8665591
169155545	169155568	4	-	27260156	PATU8988T	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.931907801010419	[246]	[903,258,311,318]	9	hSpCas9	negative selection	8722586
169130118	169130141	4	+	27260156	PATU8988T	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.5496641659493571	[493]	[627,705,737,724]	8	hSpCas9	negative selection	8722587
169130137	169130160	4	-	27260156	PATU8988T	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.4297553250116444	[645]	[875,1038,625,843]	7	hSpCas9	negative selection	8722588
169156635	169156658	4	+	27260156	PATU8988T	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.04097102846146386	[539]	[519,467,506,531]	0	hSpCas9	negative selection	8786840
169156540	169156563	4	-	27260156	PATU8988T	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.27277149373031256	[437]	[592,161,255,375]	-4	hSpCas9	negative selection	8786841
169155518	169155541	4	-	27260156	PATU8988T	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.5362801940528945	[276]	[465,360,372,346]	8	hSpCas9	negative selection	8786842
169155545	169155568	4	-	27260156	T47D	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.4430396079954232	[246]	[340,408,367,446]	8	hSpCas9	negative selection	8843837
169130118	169130141	4	+	27260156	T47D	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.3171432170811933	[493]	[797,600,669,812]	6	hSpCas9	negative selection	8843838
169130137	169130160	4	-	27260156	T47D	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.047197229669901974	[645]	[653,691,804,764]	-1	hSpCas9	negative selection	8843839
169156635	169156658	4	+	27260156	T47D	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.1650045743136346	[539]	[624,533,595,488]	-4	hSpCas9	negative selection	8908091
169156540	169156563	4	-	27260156	T47D	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.01984122909652919	[437]	[464,503,543,498]	0	hSpCas9	negative selection	8908092
169155518	169155541	4	-	27260156	T47D	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.08122149643797538	[276]	[309,355,331,366]	1	hSpCas9	negative selection	8908093
169155545	169155568	4	-	27260156	SU8686	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.09959260900761002	[246]	[289,178,182,427]	1	hSpCas9	negative selection	8965088
169130118	169130141	4	+	27260156	SU8686	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.555433596334903	[493]	[756,450,864,857]	8	hSpCas9	negative selection	8965089
169130137	169130160	4	-	27260156	SU8686	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.025356413034699876	[645]	[486,580,755,839]	0	hSpCas9	negative selection	8965090
169156635	169156658	4	+	27260156	SU8686	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.007594224774052694	[539]	[577,429,591,563]	0	hSpCas9	negative selection	9029342
169156540	169156563	4	-	27260156	SU8686	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.025042321659010353	[437]	[394,311,469,569]	0	hSpCas9	negative selection	9029343
169155518	169155541	4	-	27260156	SU8686	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.3899680682430158	[276]	[295,207,155,156]	-6	hSpCas9	negative selection	9029344
169155545	169155568	4	-	27260156	SKES1	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.6052717807808474	[246]	[287,400,361,428]	9	hSpCas9	negative selection	9086339
169130118	169130141	4	+	27260156	SKES1	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.30119241413558007	[493]	[693,679,546,531]	6	hSpCas9	negative selection	9086340
169130137	169130160	4	-	27260156	SKES1	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.002259348976015485	[645]	[565,811,686,531]	0	hSpCas9	negative selection	9086341
169156635	169156658	4	+	27260156	SKES1	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.23225511907452123	[539]	[524,474,563,294]	-5	hSpCas9	negative selection	9150593
169156540	169156563	4	-	27260156	SKES1	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.45421010124207667	[437]	[374,204,390,296]	-7	hSpCas9	negative selection	9150594
169155518	169155541	4	-	27260156	SKES1	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.09971495928603058	[276]	[373,297,230,158]	-2	hSpCas9	negative selection	9150595
169155545	169155568	4	-	27260156	TOV112D	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.655327199033972	[246]	[245,521,408,400]	9	hSpCas9	negative selection	9207590
169130118	169130141	4	+	27260156	TOV112D	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.7081875638990573	[493]	[657,1009,1048,558]	9	hSpCas9	negative selection	9207591
169130137	169130160	4	-	27260156	TOV112D	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.1471668658411016	[645]	[729,785,370,512]	-3	hSpCas9	negative selection	9207592
169156635	169156658	4	+	27260156	TOV112D	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.026641364694622804	[539]	[590,522,408,600]	0	hSpCas9	negative selection	9271844
169156540	169156563	4	-	27260156	TOV112D	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.12215556826802187	[437]	[523,445,391,273]	-2	hSpCas9	negative selection	9271845
169155518	169155541	4	-	27260156	TOV112D	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.24110378436084712	[276]	[346,457,332,209]	4	hSpCas9	negative selection	9271846
169155545	169155568	4	-	27260156	TC71	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.3530101086873725	[246]	[311,372,364,299]	8	hSpCas9	negative selection	9328841
169130118	169130141	4	+	27260156	TC71	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.29884370217266015	[493]	[472,793,722,614]	7	hSpCas9	negative selection	9328842
169130137	169130160	4	-	27260156	TC71	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	0.03904913491838996	[645]	[808,664,702,663]	1	hSpCas9	negative selection	9328843
169156635	169156658	4	+	27260156	TC71	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	0.06839939644676932	[539]	[687,589,622,518]	1	hSpCas9	negative selection	9393095
169156540	169156563	4	-	27260156	TC71	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.1244726241622095	[437]	[371,507,439,401]	-3	hSpCas9	negative selection	9393096
169155518	169155541	4	-	27260156	TC71	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	-0.05592054341157304	[276]	[264,291,314,268]	-1	hSpCas9	negative selection	9393097
169155545	169155568	4	-	27260156	TC32	viability	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.5950299951388488	[246]	[302,326,382,389]	8	hSpCas9	negative selection	9450092
169130118	169130141	4	+	27260156	TC32	viability	GGGCGGGGTCACAATTAACCCGG	SH3RF1	ENSG00000154447	0.27531763479926713	[493]	[610,468,558,602]	5	hSpCas9	negative selection	9450093
169130137	169130160	4	-	27260156	TC32	viability	CAGGTTCATATAAGTACCACCGG	SH3RF1	ENSG00000154447	-0.33145894212610794	[645]	[553,311,676,444]	-6	hSpCas9	negative selection	9450094
169156635	169156658	4	+	27260156	TC32	viability	TTCATAGTTGTATAATGCTTTGG	SH3RF1	ENSG00000154447	-0.021131633049420284	[539]	[440,492,695,374]	0	hSpCas9	negative selection	9514346
169156540	169156563	4	-	27260156	TC32	viability	TGGTACCATGGGGAAGTCAATGG	SH3RF1	ENSG00000154447	-0.5852573726773336	[437]	[315,116,354,367]	-8	hSpCas9	negative selection	9514347
169155518	169155541	4	-	27260156	TC32	viability	AAACTGGGCTGAAGGAATGCTGG	SH3RF1	ENSG00000154447	0.053311328263908164	[276]	[165,279,268,362]	1	hSpCas9	negative selection	9514348
169116584	169116607	4	+	27869803	HPAFII	viability after 27 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	1.3242861308822902	[53]	[111,36,NaN]	9	hSpCas9	negative selection	9587490
169117522	169117545	4	-	27869803	HPAFII	viability after 27 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	0.486757653321834	[336]	[376,140,NaN]	4	hSpCas9	negative selection	9587491
169130095	169130118	4	-	27869803	HPAFII	viability after 27 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.27574366717394594	[858]	[657,453,NaN]	2	hSpCas9	negative selection	9587492
169136559	169136582	4	+	27869803	HPAFII	viability after 27 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.06971330379669219	[215]	[98,135,NaN]	0	hSpCas9	negative selection	9587493
169155545	169155568	4	-	27869803	HPAFII	viability after 27 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.070084415063276	[506]	[197,347,NaN]	0	hSpCas9	negative selection	9587494
169268962	169268985	4	-	27869803	HPAFII	viability after 27 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.7824425427292561	[359]	[330,320,NaN]	6	hSpCas9	negative selection	9587495
169116584	169116607	4	+	27869803	HPAFII	viability after 15 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	0.8848189273556171	[53]	[256,13,NaN]	8	hSpCas9	negative selection	9669939
169117522	169117545	4	-	27869803	HPAFII	viability after 15 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	0.3393090990934445	[336]	[464,453,NaN]	4	hSpCas9	negative selection	9669940
169130095	169130118	4	-	27869803	HPAFII	viability after 15 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.13707672717909936	[858]	[1140,936,NaN]	1	hSpCas9	negative selection	9669941
169136559	169136582	4	+	27869803	HPAFII	viability after 15 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	-0.8556990048570379	[215]	[102,143,NaN]	-7	hSpCas9	negative selection	9669942
169155545	169155568	4	-	27869803	HPAFII	viability after 15 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	-0.19362290479092392	[506]	[518,449,NaN]	-2	hSpCas9	negative selection	9669943
169268962	169268985	4	-	27869803	HPAFII	viability after 15 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.573951581452304	[359]	[837,412,NaN]	6	hSpCas9	negative selection	9669944
169116584	169116607	4	+	27869803	ASPC1	viability after 36 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	0.857972161810343	[238]	[0,154,251]	8	hSpCas9	negative selection	9752388
169117522	169117545	4	-	27869803	ASPC1	viability after 36 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.5471033426552994	[785]	[473,52,91]	-5	hSpCas9	negative selection	9752389
169130095	169130118	4	-	27869803	ASPC1	viability after 36 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	1.2485907569794241	[1941]	[1354,2090,1391]	9	hSpCas9	negative selection	9752390
169136559	169136582	4	+	27869803	ASPC1	viability after 36 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	-0.3277122949962612	[460]	[134,111,134]	-3	hSpCas9	negative selection	9752391
169155545	169155568	4	-	27869803	ASPC1	viability after 36 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	1.1097511515263399	[1194]	[879,811,974]	9	hSpCas9	negative selection	9752392
169268962	169268985	4	-	27869803	ASPC1	viability after 36 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	-0.265570642414132	[1100]	[424,342,223]	-3	hSpCas9	negative selection	9752393
169116584	169116607	4	+	27869803	PATU8988S	viability after 35 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	2.003941648487125	[206]	[285,382,NaN]	9	hSpCas9	negative selection	9834837
169117522	169117545	4	-	27869803	PATU8988S	viability after 35 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	-0.053684205902258864	[635]	[155,337,NaN]	0	hSpCas9	negative selection	9834838
169130095	169130118	4	-	27869803	PATU8988S	viability after 35 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	-0.17443797824415985	[2122]	[608,906,NaN]	-2	hSpCas9	negative selection	9834839
169136559	169136582	4	+	27869803	PATU8988S	viability after 35 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.6264631162502942	[345]	[270,158,NaN]	7	hSpCas9	negative selection	9834840
169155545	169155568	4	-	27869803	PATU8988S	viability after 35 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.01308813045297752	[804]	[400,252,NaN]	0	hSpCas9	negative selection	9834841
169268962	169268985	4	-	27869803	PATU8988S	viability after 35 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.44659323301167864	[1074]	[607,571,NaN]	5	hSpCas9	negative selection	9834842
169116584	169116607	4	+	27869803	PATU8988S	viability after 31 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	1.70780737818138	[206]	[211,342,NaN]	9	hSpCas9	negative selection	9917286
169117522	169117545	4	-	27869803	PATU8988S	viability after 31 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	0.3110776365076833	[635]	[245,401,NaN]	4	hSpCas9	negative selection	9917287
169130095	169130118	4	-	27869803	PATU8988S	viability after 31 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	-0.1720773322323459	[2122]	[515,1050,NaN]	-2	hSpCas9	negative selection	9917288
169136559	169136582	4	+	27869803	PATU8988S	viability after 31 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.5836497294155379	[345]	[204,208,NaN]	7	hSpCas9	negative selection	9917289
169155545	169155568	4	-	27869803	PATU8988S	viability after 31 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.012249970719908632	[804]	[350,288,NaN]	0	hSpCas9	negative selection	9917290
169268962	169268985	4	-	27869803	PATU8988S	viability after 31 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.15106778891577166	[1074]	[515,424,NaN]	2	hSpCas9	negative selection	9917291
169116584	169116607	4	+	27869803	HPAFII	viability after 35 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	1.2772002205854214	[53]	[109,16,NaN]	8	hSpCas9	negative selection	9999735
169117522	169117545	4	-	27869803	HPAFII	viability after 35 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	1.3280428514446916	[336]	[607,225,NaN]	8	hSpCas9	negative selection	9999736
169130095	169130118	4	-	27869803	HPAFII	viability after 35 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.4896785566819537	[858]	[651,563,NaN]	3	hSpCas9	negative selection	9999737
169136559	169136582	4	+	27869803	HPAFII	viability after 35 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.43961813438959774	[215]	[168,124,NaN]	3	hSpCas9	negative selection	9999738
169155545	169155568	4	-	27869803	HPAFII	viability after 35 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.003667285986854063	[506]	[190,331,NaN]	0	hSpCas9	negative selection	9999739
169268962	169268985	4	-	27869803	HPAFII	viability after 35 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	1.010322233725619	[359]	[241,507,NaN]	6	hSpCas9	negative selection	9999740
169116584	169116607	4	+	27869803	HPAFII	viability after 31 days	GATGGGTGTCACTGCTGCCGTGG	SH3RF1	ENSG00000154447	1.0741297271693013	[53]	[92,31,NaN]	7	hSpCas9	negative selection	10082184
169117522	169117545	4	-	27869803	HPAFII	viability after 31 days	GCCCGCAATGCTGTGAGGACAGG	SH3RF1	ENSG00000154447	0.3047952175711531	[336]	[347,108,NaN]	2	hSpCas9	negative selection	10082185
169130095	169130118	4	-	27869803	HPAFII	viability after 31 days	CCAAGCAGCCCAGTGACAACTGG	SH3RF1	ENSG00000154447	0.167902752939028	[858]	[643,429,NaN]	1	hSpCas9	negative selection	10082186
169136559	169136582	4	+	27869803	HPAFII	viability after 31 days	GCATCAACTCCTGGCACAGGAGG	SH3RF1	ENSG00000154447	0.4387978029561295	[215]	[148,180,NaN]	3	hSpCas9	negative selection	10082187
169155545	169155568	4	-	27869803	HPAFII	viability after 31 days	TCTGACTGTGATCCGAAGAGTGG	SH3RF1	ENSG00000154447	0.24128743406812192	[506]	[220,461,NaN]	1	hSpCas9	negative selection	10082188
169268962	169268985	4	-	27869803	HPAFII	viability after 31 days	AAACAGAGGCCTTGGAAACCTGG	SH3RF1	ENSG00000154447	0.8785700614772929	[359]	[269,481,NaN]	6	hSpCas9	negative selection	10082189
169268860	169268883	4	-	28162770	P31FUJ	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	-0.3284855524696866	[186]	[174]	-3	hSpCas9	negative selection	10233684
169117720	169117743	4	-	28162770	P31FUJ	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	0.590320033501542	[155]	[275]	6	hSpCas9	negative selection	10233685
169156600	169156623	4	-	28162770	P31FUJ	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	0.44798578880684187	[198]	[318]	5	hSpCas9	negative selection	10233686
169268900	169268923	4	-	28162770	P31FUJ	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	0.9186501369564548	[130]	[290]	9	hSpCas9	negative selection	10233687
169268830	169268853	4	+	28162770	P31FUJ	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	1.0251535613816545	[165]	[396]	9	hSpCas9	negative selection	10233688
169156535	169156558	4	+	28162770	P31FUJ	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.21433613803148943	[299]	[408]	2	hSpCas9	negative selection	10233689
169136444	169136467	4	+	28162770	P31FUJ	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.3752656565695699	[350]	[534]	4	hSpCas9	negative selection	10233690
169136404	169136427	4	+	28162770	P31FUJ	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	0.006720494658696674	[298]	[352]	0	hSpCas9	negative selection	10233691
169130121	169130144	4	+	28162770	P31FUJ	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.3988913466517686	[161]	[250]	4	hSpCas9	negative selection	10233692
169130071	169130094	4	+	28162770	P31FUJ	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.06798712341483326	[219]	[270]	0	hSpCas9	negative selection	10233693
169268860	169268883	4	-	28162770	TF1	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	NaN	[NaN]	[126]	1	hSpCas9	negative selection	10403050
169117720	169117743	4	-	28162770	TF1	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10403051
169156600	169156623	4	-	28162770	TF1	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10403052
169268900	169268923	4	-	28162770	TF1	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	NaN	[NaN]	[174]	1	hSpCas9	negative selection	10403053
169268830	169268853	4	+	28162770	TF1	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	NaN	[NaN]	[243]	1	hSpCas9	negative selection	10403054
169156535	169156558	4	+	28162770	TF1	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10403055
169136444	169136467	4	+	28162770	TF1	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	NaN	[NaN]	[383]	1	hSpCas9	negative selection	10403056
169136404	169136427	4	+	28162770	TF1	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	NaN	[NaN]	[302]	1	hSpCas9	negative selection	10403057
169130121	169130144	4	+	28162770	TF1	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10403058
169130071	169130094	4	+	28162770	TF1	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10403059
169268860	169268883	4	-	28162770	SKM1	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	-0.4894263589351347	[53]	[67]	-4	hSpCas9	negative selection	10572416
169117720	169117743	4	-	28162770	SKM1	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	-0.46836474340730516	[35]	[45]	-4	hSpCas9	negative selection	10572417
169156600	169156623	4	-	28162770	SKM1	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	-0.4405725913859814	[75]	[98]	-4	hSpCas9	negative selection	10572418
169268900	169268923	4	-	28162770	SKM1	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	-0.6844981742720707	[59]	[65]	-5	hSpCas9	negative selection	10572419
169268830	169268853	4	+	28162770	SKM1	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	-0.48639866623756656	[41]	[52]	-4	hSpCas9	negative selection	10572420
169156535	169156558	4	+	28162770	SKM1	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	-0.23703919730084955	[71]	[107]	-2	hSpCas9	negative selection	10572421
169136444	169136467	4	+	28162770	SKM1	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.17111191639275458	[104]	[208]	1	hSpCas9	negative selection	10572422
169136404	169136427	4	+	28162770	SKM1	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	0.6247983636416259	[72]	[198]	6	hSpCas9	negative selection	10572423
169130121	169130144	4	+	28162770	SKM1	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.886949519974604	[25]	[84]	8	hSpCas9	negative selection	10572424
169130071	169130094	4	+	28162770	SKM1	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.19294864344396606	[47]	[96]	1	hSpCas9	negative selection	10572425
169268860	169268883	4	-	28162770	SKM1	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	-0.4894263589351347	[53]	[67]	-4	hSpCas9	negative selection	10741782
169117720	169117743	4	-	28162770	SKM1	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	-0.46836474340730516	[35]	[45]	-4	hSpCas9	negative selection	10741783
169156600	169156623	4	-	28162770	SKM1	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	-0.4405725913859814	[75]	[98]	-4	hSpCas9	negative selection	10741784
169268900	169268923	4	-	28162770	SKM1	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	-0.6844981742720707	[59]	[65]	-5	hSpCas9	negative selection	10741785
169268830	169268853	4	+	28162770	SKM1	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	-0.48639866623756656	[41]	[52]	-4	hSpCas9	negative selection	10741786
169156535	169156558	4	+	28162770	SKM1	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	-0.23703919730084955	[71]	[107]	-2	hSpCas9	negative selection	10741787
169136444	169136467	4	+	28162770	SKM1	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.17111191639275458	[104]	[208]	1	hSpCas9	negative selection	10741788
169136404	169136427	4	+	28162770	SKM1	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	0.6247983636416259	[72]	[198]	6	hSpCas9	negative selection	10741789
169130121	169130144	4	+	28162770	SKM1	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.886949519974604	[25]	[84]	8	hSpCas9	negative selection	10741790
169130071	169130094	4	+	28162770	SKM1	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.19294864344396606	[47]	[96]	1	hSpCas9	negative selection	10741791
169268860	169268883	4	-	28162770	PL21	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	-0.05204740910748115	[211]	[88]	0	hSpCas9	negative selection	10911148
169117720	169117743	4	-	28162770	PL21	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	-0.5034673827304549	[113]	[34]	-4	hSpCas9	negative selection	10911149
169156600	169156623	4	-	28162770	PL21	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	0.47731820264338376	[202]	[122]	4	hSpCas9	negative selection	10911150
169268900	169268923	4	-	28162770	PL21	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	-0.004974815415292266	[165]	[71]	0	hSpCas9	negative selection	10911151
169268830	169268853	4	+	28162770	PL21	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	-0.6426206436994828	[164]	[45]	-4	hSpCas9	negative selection	10911152
169156535	169156558	4	+	28162770	PL21	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.5714557363388462	[401]	[259]	5	hSpCas9	negative selection	10911153
169136444	169136467	4	+	28162770	PL21	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.9743581167428164	[315]	[69]	-6	hSpCas9	negative selection	10911154
169136404	169136427	4	+	28162770	PL21	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	-0.39480697480445825	[289]	[95]	-3	hSpCas9	negative selection	10911155
169130121	169130144	4	+	28162770	PL21	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.038676191795203874	[84]	[37]	0	hSpCas9	negative selection	10911156
169130071	169130094	4	+	28162770	PL21	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	-0.6655592937990888	[163]	[44]	-5	hSpCas9	negative selection	10911157
169268860	169268883	4	-	28162770	P31FUJ	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	-0.3284855524696866	[186]	[174]	-3	hSpCas9	negative selection	11080514
169117720	169117743	4	-	28162770	P31FUJ	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	0.590320033501542	[155]	[275]	6	hSpCas9	negative selection	11080515
169156600	169156623	4	-	28162770	P31FUJ	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	0.44798578880684187	[198]	[318]	5	hSpCas9	negative selection	11080516
169268900	169268923	4	-	28162770	P31FUJ	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	0.9186501369564548	[130]	[290]	9	hSpCas9	negative selection	11080517
169268830	169268853	4	+	28162770	P31FUJ	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	1.0251535613816545	[165]	[396]	9	hSpCas9	negative selection	11080518
169156535	169156558	4	+	28162770	P31FUJ	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.21433613803148943	[299]	[408]	2	hSpCas9	negative selection	11080519
169136444	169136467	4	+	28162770	P31FUJ	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.3752656565695699	[350]	[534]	4	hSpCas9	negative selection	11080520
169136404	169136427	4	+	28162770	P31FUJ	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	0.006720494658696674	[298]	[352]	0	hSpCas9	negative selection	11080521
169130121	169130144	4	+	28162770	P31FUJ	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.3988913466517686	[161]	[250]	4	hSpCas9	negative selection	11080522
169130071	169130094	4	+	28162770	P31FUJ	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.06798712341483326	[219]	[270]	0	hSpCas9	negative selection	11080523
169268860	169268883	4	-	28162770	OCIAML5	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	0.08869422576132685	[86]	[166]	0	hSpCas9	negative selection	11249880
169117720	169117743	4	-	28162770	OCIAML5	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	0.14793342913600294	[62]	[125]	1	hSpCas9	negative selection	11249881
169156600	169156623	4	-	28162770	OCIAML5	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	1.0040240177372897	[157]	[571]	8	hSpCas9	negative selection	11249882
169268900	169268923	4	-	28162770	OCIAML5	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	0.8382489300033877	[87]	[283]	7	hSpCas9	negative selection	11249883
169268830	169268853	4	+	28162770	OCIAML5	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	1.2820986674607155	[58]	[258]	9	hSpCas9	negative selection	11249884
169156535	169156558	4	+	28162770	OCIAML5	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.2137859764306287	[181]	[380]	1	hSpCas9	negative selection	11249885
169136444	169136467	4	+	28162770	OCIAML5	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.08236419028579112	[182]	[311]	0	hSpCas9	negative selection	11249886
169136404	169136427	4	+	28162770	OCIAML5	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	0.6650805456295876	[195]	[560]	6	hSpCas9	negative selection	11249887
169130121	169130144	4	+	28162770	OCIAML5	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	-0.8164426611332756	[79]	[81]	-5	hSpCas9	negative selection	11249888
169130071	169130094	4	+	28162770	OCIAML5	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.0667966664105975	[127]	[241]	0	hSpCas9	negative selection	11249889
169268860	169268883	4	-	28162770	EOL1	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	-1.4246017920518521	[320]	[62]	-7	hSpCas9	negative selection	11419246
169117720	169117743	4	-	28162770	EOL1	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	1.053830788515501	[159]	[174]	8	hSpCas9	negative selection	11419247
169156600	169156623	4	-	28162770	EOL1	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	0.44677451694372816	[375]	[269]	4	hSpCas9	negative selection	11419248
169268900	169268923	4	-	28162770	EOL1	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	-0.2652767873094826	[291]	[127]	-2	hSpCas9	negative selection	11419249
169268830	169268853	4	+	28162770	EOL1	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	0.3002271863962982	[352]	[228]	2	hSpCas9	negative selection	11419250
169156535	169156558	4	+	28162770	EOL1	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	-0.8693296465695289	[585]	[168]	-6	hSpCas9	negative selection	11419251
169136444	169136467	4	+	28162770	EOL1	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	1.3750383564675457	[411]	[562]	9	hSpCas9	negative selection	11419252
169136404	169136427	4	+	28162770	EOL1	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	-0.1800411297066651	[285]	[132]	-1	hSpCas9	negative selection	11419253
169130121	169130144	4	+	28162770	EOL1	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.2648879035717773	[108]	[68]	2	hSpCas9	negative selection	11419254
169130071	169130094	4	+	28162770	EOL1	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	1.0197050046108744	[219]	[234]	8	hSpCas9	negative selection	11419255
169268860	169268883	4	-	28162770	MOLM13	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	0.021990918560974473	[251]	[184]	0	hSpCas9	negative selection	11588612
169117720	169117743	4	-	28162770	MOLM13	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	-0.8433123067497252	[133]	[53]	-5	hSpCas9	negative selection	11588613
169156600	169156623	4	-	28162770	MOLM13	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	0.6595094540862103	[351]	[401]	5	hSpCas9	negative selection	11588614
169268900	169268923	4	-	28162770	MOLM13	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	0.4162272617220862	[198]	[191]	3	hSpCas9	negative selection	11588615
169268830	169268853	4	+	28162770	MOLM13	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	-0.28057185145945684	[209]	[124]	-2	hSpCas9	negative selection	11588616
169156535	169156558	4	+	28162770	MOLM13	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	-0.038258735999748605	[560]	[394]	0	hSpCas9	negative selection	11588617
169136444	169136467	4	+	28162770	MOLM13	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.6385615600860637	[477]	[221]	-4	hSpCas9	negative selection	11588618
169136404	169136427	4	+	28162770	MOLM13	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	0.61618850622621	[350]	[388]	4	hSpCas9	negative selection	11588619
169130121	169130144	4	+	28162770	MOLM13	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	-0.687388843933332	[97]	[43]	-4	hSpCas9	negative selection	11588620
169130071	169130094	4	+	28162770	MOLM13	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.5523856556313521	[314]	[333]	4	hSpCas9	negative selection	11588621
169268860	169268883	4	-	28162770	HEL	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	-1.7568686267088807	[247]	[46]	-7	hSpCas9	negative selection	11757978
169117720	169117743	4	-	28162770	HEL	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	-0.06579835383933186	[133]	[81]	0	hSpCas9	negative selection	11757979
169156600	169156623	4	-	28162770	HEL	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	0.5921127589303891	[318]	[307]	5	hSpCas9	negative selection	11757980
169268900	169268923	4	-	28162770	HEL	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	1.1332665308634642	[241]	[339]	8	hSpCas9	negative selection	11757981
169268830	169268853	4	+	28162770	HEL	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	1.8440182661836066	[176]	[406]	9	hSpCas9	negative selection	11757982
169156535	169156558	4	+	28162770	HEL	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.037484927286124625	[536]	[352]	0	hSpCas9	negative selection	11757983
169136444	169136467	4	+	28162770	HEL	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	1.0164173015181432	[344]	[446]	8	hSpCas9	negative selection	11757984
169136404	169136427	4	+	28162770	HEL	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	0.8051408747276596	[234]	[262]	7	hSpCas9	negative selection	11757985
169130121	169130144	4	+	28162770	HEL	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.33934668855042216	[115]	[93]	3	hSpCas9	negative selection	11757986
169130071	169130094	4	+	28162770	HEL	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	-0.6914155652202647	[236]	[93]	-4	hSpCas9	negative selection	11757987
169268860	169268883	4	-	28162770	MV411	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	0.34931716480198893	[163]	[175]	3	hSpCas9	negative selection	11927344
169117720	169117743	4	-	28162770	MV411	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	-0.8955204030592676	[105]	[47]	-6	hSpCas9	negative selection	11927345
169156600	169156623	4	-	28162770	MV411	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	-0.382193999272109	[245]	[158]	-3	hSpCas9	negative selection	11927346
169268900	169268923	4	-	28162770	MV411	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	0.0014583091287115168	[184]	[155]	0	hSpCas9	negative selection	11927347
169268830	169268853	4	+	28162770	MV411	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	0.47910778570723395	[154]	[181]	4	hSpCas9	negative selection	11927348
169156535	169156558	4	+	28162770	MV411	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.04580368961312481	[252]	[219]	0	hSpCas9	negative selection	11927349
169136444	169136467	4	+	28162770	MV411	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	-0.2030646291508721	[301]	[220]	-1	hSpCas9	negative selection	11927350
169136404	169136427	4	+	28162770	MV411	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	-0.20208832488135908	[253]	[185]	-1	hSpCas9	negative selection	11927351
169130121	169130144	4	+	28162770	MV411	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.02504512944632742	[83]	[71]	0	hSpCas9	negative selection	11927352
169130071	169130094	4	+	28162770	MV411	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.5065247720999063	[121]	[145]	4	hSpCas9	negative selection	11927353
169268860	169268883	4	-	28162770	MONOMAC1	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	-0.7012680756678529	[138]	[97]	-5	hSpCas9	negative selection	12096710
169117720	169117743	4	-	28162770	MONOMAC1	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	-0.1133789180126441	[66]	[70]	-1	hSpCas9	negative selection	12096711
169156600	169156623	4	-	28162770	MONOMAC1	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	1.0790242390704798	[146]	[355]	8	hSpCas9	negative selection	12096712
169268900	169268923	4	-	28162770	MONOMAC1	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	-0.66199957167008	[97]	[70]	-5	hSpCas9	negative selection	12096713
169268830	169268853	4	+	28162770	MONOMAC1	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	0.2902289797744692	[111]	[156]	3	hSpCas9	negative selection	12096714
169156535	169156558	4	+	28162770	MONOMAC1	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	0.01964192308250068	[252]	[293]	0	hSpCas9	negative selection	12096715
169136444	169136467	4	+	28162770	MONOMAC1	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	1.7973459036341926	[192]	[768]	9	hSpCas9	negative selection	12096716
169136404	169136427	4	+	28162770	MONOMAC1	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	0.614635370112829	[142]	[250]	6	hSpCas9	negative selection	12096717
169130121	169130144	4	+	28162770	MONOMAC1	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.0626069695734659	[70]	[84]	0	hSpCas9	negative selection	12096718
169130071	169130094	4	+	28162770	MONOMAC1	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.59860465443426	[105]	[183]	6	hSpCas9	negative selection	12096719
169268860	169268883	4	-	28162770	OCIAML2	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	0.20607524410657038	[32]	[210]	2	hSpCas9	negative selection	12266076
169117720	169117743	4	-	28162770	OCIAML2	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	0.6750476299534739	[19]	[176]	6	hSpCas9	negative selection	12266077
169156600	169156623	4	-	28162770	OCIAML2	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	-0.33425738351087547	[57]	[254]	-3	hSpCas9	negative selection	12266078
169268900	169268923	4	-	28162770	OCIAML2	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	0.8878241456703149	[38]	[399]	8	hSpCas9	negative selection	12266079
169268830	169268853	4	+	28162770	OCIAML2	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	-0.3331263014922264	[24]	[109]	-3	hSpCas9	negative selection	12266080
169156535	169156558	4	+	28162770	OCIAML2	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	-0.5558771118606723	[60]	[229]	-4	hSpCas9	negative selection	12266081
169136444	169136467	4	+	28162770	OCIAML2	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.4464565374722459	[46]	[354]	4	hSpCas9	negative selection	12266082
169136404	169136427	4	+	28162770	OCIAML2	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	0.00810234935407217	[53]	[300]	0	hSpCas9	negative selection	12266083
169130121	169130144	4	+	28162770	OCIAML2	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	0.7688361094532283	[8]	[84]	7	hSpCas9	negative selection	12266084
169130071	169130094	4	+	28162770	OCIAML2	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.25910419969296905	[29]	[198]	2	hSpCas9	negative selection	12266085
169268860	169268883	4	-	28162770	OCIAML3	viability	GATCTGCAGAGCTCCCAGGGCGG	SH3RF1	ENSG00000154447	-0.15862149565351696	[43]	[118]	-1	hSpCas9	negative selection	12435442
169117720	169117743	4	-	28162770	OCIAML3	viability	ACAGCTGGCCAGACAAGTCGGGG	SH3RF1	ENSG00000154447	0.01604584135982351	[37]	[115]	0	hSpCas9	negative selection	12435443
169156600	169156623	4	-	28162770	OCIAML3	viability	GGAGACCTTAAATTCAGCAAAGG	SH3RF1	ENSG00000154447	0.38278496851451155	[46]	[184]	3	hSpCas9	negative selection	12435444
169268900	169268923	4	-	28162770	OCIAML3	viability	AAGGTCTCAGAGCAGCACTGTGG	SH3RF1	ENSG00000154447	0.8119847193516738	[29]	[158]	7	hSpCas9	negative selection	12435445
169268830	169268853	4	+	28162770	OCIAML3	viability	GGGCTCCAGGATTGCACCCGAGG	SH3RF1	ENSG00000154447	-0.08304572104678387	[39]	[113]	0	hSpCas9	negative selection	12435446
169156535	169156558	4	+	28162770	OCIAML3	viability	GGATTCCATTGACTTCCCCATGG	SH3RF1	ENSG00000154447	-0.11106607654351597	[82]	[231]	-1	hSpCas9	negative selection	12435447
169136444	169136467	4	+	28162770	OCIAML3	viability	GGACTTGTTGGCCATAGTGAGGG	SH3RF1	ENSG00000154447	0.14295795384204307	[71]	[239]	1	hSpCas9	negative selection	12435448
169136404	169136427	4	+	28162770	OCIAML3	viability	GGCTGATCTCCATGGAGTGGCGG	SH3RF1	ENSG00000154447	1.426918198530385	[76]	[624]	9	hSpCas9	negative selection	12435449
169130121	169130144	4	+	28162770	OCIAML3	viability	CGGGGTCACAATTAACCCGGTGG	SH3RF1	ENSG00000154447	-0.2341116952377802	[29]	[76]	-2	hSpCas9	negative selection	12435450
169130071	169130094	4	+	28162770	OCIAML3	viability	TCTGATGGGAAAGTAAACGAGGG	SH3RF1	ENSG00000154447	0.8625064949308396	[44]	[246]	7	hSpCas9	negative selection	12435451