Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:56961
• Symbol:SHD
• Description:Src homology 2 domain containing transforming protein D

DataSource: http://genomecrispr.dkfz.de/#!/results/SHD

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
4280125	4280148	19	-	26472758	Jiyoye	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.27859117544446055	[257]	[235]	2	hSpCas9	negative selection	146435
4280053	4280076	19	+	26472758	Jiyoye	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	1.5167998726803713	[18]	[40]	8	hSpCas9	negative selection	146436
4280285	4280308	19	+	26472758	Jiyoye	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-0.05677171825391669	[39]	[28]	0	hSpCas9	negative selection	146437
4282896	4282919	19	-	26472758	Jiyoye	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.7820949696558659	[243]	[106]	-5	hSpCas9	negative selection	146438
4284806	4284829	19	+	26472758	Jiyoye	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	-0.6901218198490413	[183]	[85]	-5	hSpCas9	negative selection	146439
4280272	4280295	19	+	26472758	Jiyoye	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	0.1482221524838967	[352]	[294]	1	hSpCas9	negative selection	146440
4282877	4282900	19	-	26472758	Jiyoye	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	-2.1948606325742244	[169]	[27]	-8	hSpCas9	negative selection	146441
4283183	4283206	19	+	26472758	Jiyoye	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.2326490542498012	[66]	[42]	-2	hSpCas9	negative selection	146442
4283228	4283251	19	-	26472758	Jiyoye	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	3.214530303563477	[0]	[6]	9	hSpCas9	negative selection	146443
4284861	4284884	19	-	26472758	Jiyoye	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	-0.12184894762142529	[214]	[148]	-1	hSpCas9	negative selection	146444
4280125	4280148	19	-	26472758	KBM7	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.3896572290543945	[1207,714]	[482,665]	4	hSpCas9	negative selection	337553
4280053	4280076	19	+	26472758	KBM7	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	0.16277111568596525	[132,137]	[84,59]	1	hSpCas9	negative selection	337554
4280285	4280308	19	+	26472758	KBM7	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-0.20560601969835068	[178,156]	[32,99]	-2	hSpCas9	negative selection	337555
4282896	4282919	19	-	26472758	KBM7	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	0.2909849667751579	[720,579]	[477,276]	3	hSpCas9	negative selection	337556
4284806	4284829	19	+	26472758	KBM7	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	-0.032779925081965866	[648,512]	[252,275]	0	hSpCas9	negative selection	337557
4280272	4280295	19	+	26472758	KBM7	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	-0.038191720150181796	[1367,896]	[555,468]	0	hSpCas9	negative selection	337558
4282877	4282900	19	-	26472758	KBM7	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	-0.1845371015347963	[169,184]	[71,75]	-2	hSpCas9	negative selection	337559
4283183	4283206	19	+	26472758	KBM7	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.024231176779200725	[275,208]	[69,154]	0	hSpCas9	negative selection	337560
4283228	4283251	19	-	26472758	KBM7	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	0.4580769436800094	[79,60]	[70,21]	5	hSpCas9	negative selection	337561
4284861	4284884	19	-	26472758	KBM7	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	1.4494886579213797	[525,577]	[928,524]	9	hSpCas9	negative selection	337562
4280125	4280148	19	-	26472758	Raji	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	-0.13628554559326322	[591]	[124]	-1	hSpCas9	negative selection	528671
4280053	4280076	19	+	26472758	Raji	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	0.9919063179536636	[51]	[23]	8	hSpCas9	negative selection	528672
4280285	4280308	19	+	26472758	Raji	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	0.9629936260384249	[41]	[18]	8	hSpCas9	negative selection	528673
4282896	4282919	19	-	26472758	Raji	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	0.0008118711755553676	[322]	[74]	0	hSpCas9	negative selection	528674
4284806	4284829	19	+	26472758	Raji	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	0.6950004895407336	[180]	[67]	6	hSpCas9	negative selection	528675
4280272	4280295	19	+	26472758	Raji	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	0.27996299026188964	[542]	[152]	2	hSpCas9	negative selection	528676
4282877	4282900	19	-	26472758	Raji	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	-0.8926164646264008	[55]	[6]	-6	hSpCas9	negative selection	528677
4283183	4283206	19	+	26472758	Raji	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.6455236026616281	[181]	[26]	-5	hSpCas9	negative selection	528678
4283228	4283251	19	-	26472758	Raji	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	-0.725506478791142	[56]	[7]	-5	hSpCas9	negative selection	528679
4284861	4284884	19	-	26472758	Raji	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	0.20926314939281304	[245]	[65]	2	hSpCas9	negative selection	528680
4280125	4280148	19	-	26472758	K562	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.8879334107427161	[844]	[1319]	7	hSpCas9	negative selection	719789
4280053	4280076	19	+	26472758	K562	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	1.007090036025128	[88]	[150]	8	hSpCas9	negative selection	719790
4280285	4280308	19	+	26472758	K562	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-0.2749554314271325	[85]	[59]	-2	hSpCas9	negative selection	719791
4282896	4282919	19	-	26472758	K562	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.2843492336020961	[641]	[444]	-2	hSpCas9	negative selection	719792
4284806	4284829	19	+	26472758	K562	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	-0.5241169455006291	[384]	[225]	-3	hSpCas9	negative selection	719793
4280272	4280295	19	+	26472758	K562	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	0.019042447891177705	[967]	[827]	0	hSpCas9	negative selection	719794
4282877	4282900	19	-	26472758	K562	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	-1.7469681420288452	[166]	[41]	-7	hSpCas9	negative selection	719795
4283183	4283206	19	+	26472758	K562	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.9339118118589098	[172]	[278]	7	hSpCas9	negative selection	719796
4283228	4283251	19	-	26472758	K562	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	-2.3405437730547094	[65]	[10]	-8	hSpCas9	negative selection	719797
4284861	4284884	19	-	26472758	K562	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	0.8546038120908567	[377]	[576]	7	hSpCas9	negative selection	719798
4280312	4280335	19	+	26627737	DLD1	viability	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.2614754334257151	[651]	[291,138,89]	-3	hSpCas9	negative selection	805073
4282943	4282966	19	+	26627737	DLD1	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.7516067544978251	[197]	[155,42,109]	7	hSpCas9	negative selection	805089
4283183	4283206	19	+	26627737	DLD1	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.4156889455859513	[538]	[50,126,190]	-4	hSpCas9	negative selection	805091
4284787	4284810	19	+	26627737	DLD1	viability	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.4148011275866109	[726]	[180,95,222]	-4	hSpCas9	negative selection	805097
4288350	4288373	19	-	26627737	DLD1	viability	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.3293755732827701	[159]	[61,42,79]	3	hSpCas9	negative selection	805098
4290626	4290649	19	-	26627737	DLD1	viability	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	0.3916829537174076	[147]	[22,71,83]	4	hSpCas9	negative selection	805102
4280312	4280335	19	+	26627737	GBM cells	viability after 5 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	0.8096465367885983	[174]	[165,162]	9	hSpCas9	negative selection	887388
4282943	4282966	19	+	26627737	GBM cells	viability after 5 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.06076475428708272	[218]	[130,113]	0	hSpCas9	negative selection	887404
4283183	4283206	19	+	26627737	GBM cells	viability after 5 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.01604650848368344	[200]	[114,102]	0	hSpCas9	negative selection	887406
4284787	4284810	19	+	26627737	GBM cells	viability after 5 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.19572299925238978	[440]	[215,196]	-3	hSpCas9	negative selection	887412
4288350	4288373	19	-	26627737	GBM cells	viability after 5 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.5029851985545464	[99]	[67,83]	7	hSpCas9	negative selection	887413
4290626	4290649	19	-	26627737	GBM cells	viability after 5 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	0.37284506321809774	[107]	[81,67]	6	hSpCas9	negative selection	887417
4280312	4280335	19	+	26627737	GBM cells	viability after 13 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	0.7257154480252833	[174]	[204,117]	8	hSpCas9	negative selection	969703
4282943	4282966	19	+	26627737	GBM cells	viability after 13 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.20083780331316786	[218]	[109,97]	-2	hSpCas9	negative selection	969719
4283183	4283206	19	+	26627737	GBM cells	viability after 13 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.8371681922472128	[200]	[81,43]	-7	hSpCas9	negative selection	969721
4284787	4284810	19	+	26627737	GBM cells	viability after 13 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.1728610002492197	[440]	[246,183]	-2	hSpCas9	negative selection	969727
4288350	4288373	19	-	26627737	GBM cells	viability after 13 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.11674870282546568	[99]	[65,52]	1	hSpCas9	negative selection	969728
4290626	4290649	19	-	26627737	GBM cells	viability after 13 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	-0.5287496155773097	[107]	[33,45]	-6	hSpCas9	negative selection	969732
4280312	4280335	19	+	26627737	GBM cells	viability after 21 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	0.5274052487387486	[174]	[147,126]	5	hSpCas9	negative selection	1052018
4282943	4282966	19	+	26627737	GBM cells	viability after 21 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.1241651642818587	[218]	[116,101]	-1	hSpCas9	negative selection	1052034
4283183	4283206	19	+	26627737	GBM cells	viability after 21 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-1.5394371869995673	[200]	[35,38]	-8	hSpCas9	negative selection	1052036
4284787	4284810	19	+	26627737	GBM cells	viability after 21 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.40836891286945026	[440]	[179,180]	-4	hSpCas9	negative selection	1052042
4288350	4288373	19	-	26627737	GBM cells	viability after 21 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.9262974523200668	[99]	[120,86]	8	hSpCas9	negative selection	1052043
4290626	4290649	19	-	26627737	GBM cells	viability after 21 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	0.7042845105455761	[107]	[104,86]	7	hSpCas9	negative selection	1052047
4280312	4280335	19	+	26627737	RPE1	viability after 9 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	0.013554164884607589	[1091]	[331,361]	0	hSpCas9	negative selection	1134333
4282943	4282966	19	+	26627737	RPE1	viability after 9 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.611057246002122	[518]	[77,142]	-4	hSpCas9	negative selection	1134349
4283183	4283206	19	+	26627737	RPE1	viability after 9 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.12454294497564933	[486]	[146,190]	0	hSpCas9	negative selection	1134351
4284787	4284810	19	+	26627737	RPE1	viability after 9 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	0.48331548190487744	[733]	[346,287]	3	hSpCas9	negative selection	1134357
4288350	4288373	19	-	26627737	RPE1	viability after 9 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.2206639988850787	[131]	[31,68]	1	hSpCas9	negative selection	1134358
4290626	4290649	19	-	26627737	RPE1	viability after 9 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	1.7001156131201598	[342]	[182,562]	8	hSpCas9	negative selection	1134362
4280312	4280335	19	+	26627737	RPE1	viability after 12 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	0.025700687050079996	[1091]	[218,382]	0	hSpCas9	negative selection	1216648
4282943	4282966	19	+	26627737	RPE1	viability after 12 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.5295280327363319	[518]	[99,92]	-4	hSpCas9	negative selection	1216664
4283183	4283206	19	+	26627737	RPE1	viability after 12 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.9240248669533249	[486]	[375,112]	6	hSpCas9	negative selection	1216666
4284787	4284810	19	+	26627737	RPE1	viability after 12 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	0.6980167657815325	[733]	[367,268]	4	hSpCas9	negative selection	1216672
4288350	4288373	19	-	26627737	RPE1	viability after 12 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.0689480085353531	[131]	[26,47]	0	hSpCas9	negative selection	1216673
4290626	4290649	19	-	26627737	RPE1	viability after 12 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	1.388474491902515	[342]	[147,339]	7	hSpCas9	negative selection	1216677
4280312	4280335	19	+	26627737	RPE1	viability after 15 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.0898728785803839	[1091]	[416,167]	0	hSpCas9	negative selection	1298963
4282943	4282966	19	+	26627737	RPE1	viability after 15 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.7195068926508734	[518]	[51,124]	-4	hSpCas9	negative selection	1298979
4283183	4283206	19	+	26627737	RPE1	viability after 15 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.2935364180711808	[486]	[289,51]	2	hSpCas9	negative selection	1298981
4284787	4284810	19	+	26627737	RPE1	viability after 15 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	1.1134182908477883	[733]	[576,325]	6	hSpCas9	negative selection	1298987
4288350	4288373	19	-	26627737	RPE1	viability after 15 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.058062551901286064	[131]	[45,31]	0	hSpCas9	negative selection	1298988
4290626	4290649	19	-	26627737	RPE1	viability after 15 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	1.300277750412061	[342]	[128,344]	7	hSpCas9	negative selection	1298992
4280312	4280335	19	+	26627737	RPE1	viability after 18 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.009452584422785959	[1091]	[358,221]	0	hSpCas9	negative selection	1381278
4282943	4282966	19	+	26627737	RPE1	viability after 18 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.048193633184726914	[518]	[124,165]	0	hSpCas9	negative selection	1381294
4283183	4283206	19	+	26627737	RPE1	viability after 18 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.8322257975740383	[486]	[364,93]	5	hSpCas9	negative selection	1381296
4284787	4284810	19	+	26627737	RPE1	viability after 18 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	0.9295404934574955	[733]	[574,165]	5	hSpCas9	negative selection	1381302
4288350	4288373	19	-	26627737	RPE1	viability after 18 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	-0.27684207692880536	[131]	[11,47]	-2	hSpCas9	negative selection	1381303
4290626	4290649	19	-	26627737	RPE1	viability after 18 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	1.1419380268990584	[342]	[80,335]	6	hSpCas9	negative selection	1381307
4280312	4280335	19	+	26627737	HeLa	viability after 8 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.2225233445995669	[883]	[343,300,345]	-2	hSpCas9	negative selection	1463593
4282943	4282966	19	+	26627737	HeLa	viability after 8 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.4154208036407808	[325]	[143,318,100]	4	hSpCas9	negative selection	1463609
4283183	4283206	19	+	26627737	HeLa	viability after 8 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-1.0269643540562614	[406]	[128,68,72]	-8	hSpCas9	negative selection	1463611
4284787	4284810	19	+	26627737	HeLa	viability after 8 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	1.0293247772165666	[551]	[384,533,525]	7	hSpCas9	negative selection	1463617
4288350	4288373	19	-	26627737	HeLa	viability after 8 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.19114840457212967	[195]	[136,68,94]	1	hSpCas9	negative selection	1463618
4290626	4290649	19	-	26627737	HeLa	viability after 8 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	0.744708888591961	[166]	[342,67,10]	6	hSpCas9	negative selection	1463622
4280312	4280335	19	+	26627737	HeLa	viability after 12 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.137995321685489	[883]	[449,203,358]	-1	hSpCas9	negative selection	1545908
4282943	4282966	19	+	26627737	HeLa	viability after 12 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.5249809077774716	[325]	[258,84,250]	4	hSpCas9	negative selection	1545924
4283183	4283206	19	+	26627737	HeLa	viability after 12 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.739572493117156	[406]	[0,131,162]	-6	hSpCas9	negative selection	1545926
4284787	4284810	19	+	26627737	HeLa	viability after 12 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	0.5402788840510204	[551]	[336,259,405]	4	hSpCas9	negative selection	1545932
4288350	4288373	19	-	26627737	HeLa	viability after 12 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	-0.30277458651286415	[195]	[91,53,52]	-3	hSpCas9	negative selection	1545933
4290626	4290649	19	-	26627737	HeLa	viability after 12 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	-0.2370543963310705	[166]	[0,67,103]	-2	hSpCas9	negative selection	1545937
4280312	4280335	19	+	26627737	HeLa	viability after 15 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.4726194478738943	[883]	[238,174,372]	-4	hSpCas9	negative selection	1628223
4282943	4282966	19	+	26627737	HeLa	viability after 15 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.6154769079598665	[325]	[24,132,103]	-5	hSpCas9	negative selection	1628239
4283183	4283206	19	+	26627737	HeLa	viability after 15 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.6128939756105573	[406]	[97,156,66]	-5	hSpCas9	negative selection	1628241
4284787	4284810	19	+	26627737	HeLa	viability after 15 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	0.567446933302433	[551]	[409,315,266]	4	hSpCas9	negative selection	1628247
4288350	4288373	19	-	26627737	HeLa	viability after 15 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.23374672573560173	[195]	[126,84,66]	2	hSpCas9	negative selection	1628248
4290626	4290649	19	-	26627737	HeLa	viability after 15 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	0.8247495805954699	[166]	[84,176,97]	6	hSpCas9	negative selection	1628252
4280312	4280335	19	+	26627737	HeLa	viability after 18 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.465444499268837	[883]	[165,140,372]	-4	hSpCas9	negative selection	1710538
4282943	4282966	19	+	26627737	HeLa	viability after 18 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.6281710074233546	[325]	[12,112,103]	-5	hSpCas9	negative selection	1710554
4283183	4283206	19	+	26627737	HeLa	viability after 18 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.6346545101427343	[406]	[60,131,66]	-5	hSpCas9	negative selection	1710556
4284787	4284810	19	+	26627737	HeLa	viability after 18 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	0.5629373588110858	[551]	[267,267,266]	4	hSpCas9	negative selection	1710562
4288350	4288373	19	-	26627737	HeLa	viability after 18 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.23912279997322772	[195]	[86,68,66]	2	hSpCas9	negative selection	1710563
4290626	4290649	19	-	26627737	HeLa	viability after 18 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	0.866749903660512	[166]	[61,148,97]	6	hSpCas9	negative selection	1710567
4280312	4280335	19	+	26627737	HCT116	viability after 6 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	0.07700079304487839	[1394]	[405,134]	0	hSpCas9	negative selection	1792853
4282943	4282966	19	+	26627737	HCT116	viability after 6 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-1.6854241253220499	[660]	[50,21]	-7	hSpCas9	negative selection	1792869
4283183	4283206	19	+	26627737	HCT116	viability after 6 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-1.1164749861048189	[688]	[38,55]	-6	hSpCas9	negative selection	1792871
4284787	4284810	19	+	26627737	HCT116	viability after 6 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.5866035350410506	[856]	[61,104]	-3	hSpCas9	negative selection	1792877
4288350	4288373	19	-	26627737	HCT116	viability after 6 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	-1.3425482957962602	[99]	[11,2]	-6	hSpCas9	negative selection	1792878
4290626	4290649	19	-	26627737	HCT116	viability after 6 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	0.2508867887723174	[328]	[125,25]	1	hSpCas9	negative selection	1792882
4280312	4280335	19	+	26627737	HCT116	viability after 8 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.25132995644486855	[534]	[230,205,304]	-3	hSpCas9	negative selection	1875168
4282943	4282966	19	+	26627737	HCT116	viability after 8 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.5475188662338825	[393]	[130,139,173]	-6	hSpCas9	negative selection	1875184
4283183	4283206	19	+	26627737	HCT116	viability after 8 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.84899140173916	[253]	[276,247,231]	7	hSpCas9	negative selection	1875186
4284787	4284810	19	+	26627737	HCT116	viability after 8 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.8686954650075518	[810]	[299,257,177]	-8	hSpCas9	negative selection	1875192
4288350	4288373	19	-	26627737	HCT116	viability after 8 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	1.4768578033993551	[73]	[127,119,92]	9	hSpCas9	negative selection	1875193
4290626	4290649	19	-	26627737	HCT116	viability after 8 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	-1.0967286789688497	[333]	[66,36,152]	-8	hSpCas9	negative selection	1875197
4280312	4280335	19	+	26627737	HCT116	viability after 9 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.37307646223573876	[1394]	[524,99]	-3	hSpCas9	negative selection	1957483
4282943	4282966	19	+	26627737	HCT116	viability after 9 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-1.0126769361977743	[660]	[163,26]	-6	hSpCas9	negative selection	1957499
4283183	4283206	19	+	26627737	HCT116	viability after 9 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.3648630173382028	[688]	[291,24]	-3	hSpCas9	negative selection	1957501
4284787	4284810	19	+	26627737	HCT116	viability after 9 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	0.7110593850698017	[856]	[406,348]	5	hSpCas9	negative selection	1957507
4288350	4288373	19	-	26627737	HCT116	viability after 9 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	-2.077955024466801	[99]	[7,4]	-8	hSpCas9	negative selection	1957508
4290626	4290649	19	-	26627737	HCT116	viability after 9 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	1.0836017262955833	[328]	[255,130]	7	hSpCas9	negative selection	1957512
4280312	4280335	19	+	26627737	HCT116	viability after 12 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.3945094118148013	[534]	[132,181,332]	-4	hSpCas9	negative selection	2039798
4282943	4282966	19	+	26627737	HCT116	viability after 12 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-1.1086098879253325	[393]	[84,135,68]	-8	hSpCas9	negative selection	2039814
4283183	4283206	19	+	26627737	HCT116	viability after 12 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.9277723009737904	[253]	[320,257,176]	7	hSpCas9	negative selection	2039816
4284787	4284810	19	+	26627737	HCT116	viability after 12 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.7972619218699514	[810]	[208,329,201]	-7	hSpCas9	negative selection	2039822
4288350	4288373	19	-	26627737	HCT116	viability after 12 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	1.3056968301709269	[73]	[83,117,87]	8	hSpCas9	negative selection	2039823
4290626	4290649	19	-	26627737	HCT116	viability after 12 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	-0.7518502609436779	[333]	[98,14,196]	-7	hSpCas9	negative selection	2039827
4280312	4280335	19	+	26627737	HCT116	viability after 15 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.6712776964694759	[534]	[187,179,209]	-6	hSpCas9	negative selection	2122113
4282943	4282966	19	+	26627737	HCT116	viability after 15 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.5993788030557543	[393]	[126,141,175]	-6	hSpCas9	negative selection	2122129
4283183	4283206	19	+	26627737	HCT116	viability after 15 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.7125978552057647	[253]	[283,314,124]	6	hSpCas9	negative selection	2122131
4284787	4284810	19	+	26627737	HCT116	viability after 15 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.8361732283824078	[810]	[392,250,155]	-7	hSpCas9	negative selection	2122137
4288350	4288373	19	-	26627737	HCT116	viability after 15 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	1.3479947531838747	[73]	[109,125,88]	8	hSpCas9	negative selection	2122138
4290626	4290649	19	-	26627737	HCT116	viability after 15 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	-1.4262579225477146	[333]	[91,0,122]	-8	hSpCas9	negative selection	2122142
4280312	4280335	19	+	26627737	HCT116	viability after 18 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.17575884912411288	[534]	[217,232,235]	-1	hSpCas9	negative selection	2204428
4282943	4282966	19	+	26627737	HCT116	viability after 18 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.9023272588602314	[393]	[139,83,81]	-7	hSpCas9	negative selection	2204444
4283183	4283206	19	+	26627737	HCT116	viability after 18 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	1.2534636005941917	[253]	[355,157,376]	8	hSpCas9	negative selection	2204446
4284787	4284810	19	+	26627737	HCT116	viability after 18 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.11800119125642561	[810]	[393,457,218]	-1	hSpCas9	negative selection	2204452
4288350	4288373	19	-	26627737	HCT116	viability after 18 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	1.13739604020311	[73]	[108,49,78]	8	hSpCas9	negative selection	2204453
4290626	4290649	19	-	26627737	HCT116	viability after 18 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	0.12931123180973023	[333]	[264,1,278]	1	hSpCas9	negative selection	2204457
4286937	4286960	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGGCTGAAG	SHD	ENSG00000105251	0.17430442440476024	[13,29]	[6,2]	0	dCas9-VP64	positive selection	2446135
4286937	4286960	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGGCTGAAG	SHD	ENSG00000105251	-0.20184825873935663	[30,89]	[7,24]	-2	dCas9-VP64	positive selection	2541390
4280258	4280281	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACCATACTTGGCATCTCCGGGG	SHD	ENSG00000105251	1.0579234535375974	[1,1]	[3,3]	9	hSpCas9	positive selection	3020151
4280348	4280371	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCCACGCACCTCCTCCCCGGGG	SHD	ENSG00000105251	0.15800905530800677	[4,3]	[3,4]	3	hSpCas9	positive selection	3020152
4280165	4280188	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	0.1411022881097525	[4,4]	[4,4]	3	hSpCas9	positive selection	3020153
4282896	4282919	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.15610766233748583	[4,4]	[3,2]	-2	hSpCas9	positive selection	3020154
4280258	4280281	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACCATACTTGGCATCTCCGGGG	SHD	ENSG00000105251	0.7461494455951404	[1,1]	[1,1]	9	hSpCas9	positive selection	3088009
4280348	4280371	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCCACGCACCTCCTCCCCGGGG	SHD	ENSG00000105251	-0.08210448363565989	[4,4]	[3,2]	-1	hSpCas9	positive selection	3088010
4280165	4280188	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	0.2858385554595475	[4,4]	[3,3]	5	hSpCas9	positive selection	3088011
4282896	4282919	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	0.2334769124575461	[4,4]	[5,2]	4	hSpCas9	positive selection	3088012
4280137	4280160		+	24336571	A375	resistance to PLX after 7 days	ACACCGAGAGCGACATCCTGAGG	SHD	ENSG00000105251	0.05288279044318067	[16,22]	[20,20]	2	hSpCas9	positive selection	3144090
4280165	4280188		-	24336571	A375	resistance to PLX after 7 days	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	-0.13498431721695814	[7,9]	[7,7]	-4	hSpCas9	positive selection	3144091
4282943	4282966		+	24336571	A375	resistance to PLX after 7 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.0004211148102488127	[13,16]	[13,16]	0	hSpCas9	positive selection	3144092
4280137	4280160		+	24336571	A375	resistance to PLX after 14 days	ACACCGAGAGCGACATCCTGAGG	SHD	ENSG00000105251	0.6355401607700357	[14,18]	[12,11]	6	hSpCas9	positive selection	3201883
4280165	4280188		-	24336571	A375	resistance to PLX after 14 days	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	-0.9672951056964016	[11,9]	[1,2]	-9	hSpCas9	positive selection	3201884
4282943	4282966		+	24336571	A375	resistance to PLX after 14 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.23090757461921813	[10,10]	[6,4]	2	hSpCas9	positive selection	3201885
4280137	4280160		+	24336571	A375	viability after 7 days	ACACCGAGAGCGACATCCTGAGG	SHD	ENSG00000105251	-0.5286317532130137	[30]	[16,22]	-6	hSpCas9	negative selection	3259676
4280165	4280188		-	24336571	A375	viability after 7 days	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	0.051181022724280156	[8]	[7,9]	0	hSpCas9	negative selection	3259677
4282943	4282966		+	24336571	A375	viability after 7 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.06723462929440949	[16]	[13,16]	-1	hSpCas9	negative selection	3259678
4280137	4280160		+	24336571	A375	viability after 14 days	ACACCGAGAGCGACATCCTGAGG	SHD	ENSG00000105251	-0.7614808494074963	[30]	[14,18]	-7	hSpCas9	negative selection	3317469
4280165	4280188		-	24336571	A375	viability after 14 days	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	0.4007243650952796	[8]	[11,9]	5	hSpCas9	negative selection	3317470
4282943	4282966		+	24336571	A375	viability after 14 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.5291688206038251	[16]	[10,10]	-6	hSpCas9	negative selection	3317471
4280162	4280185	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	-0.16893854325626279	[171,171]	[0,0]	-1	hSpCas9	positive selection	3392327
4282959	4282982	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-1.2544264423215443	[364,364]	[0,0]	-8	hSpCas9	positive selection	3392328
4283047	4283070	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	0.8564467751636508	[168,168]	[1,1]	4	hSpCas9	positive selection	3392329
4280258	4280281	19	-	26780180	HT29	viability (Avana library 4 designs)	AACCATACTTGGCATCTCCGGGG	SHD	ENSG00000105251	1.26332355277665	[]	[]	5	hSpCas9	negative selection	3458655
4280348	4280371	19	-	26780180	HT29	viability (Avana library 4 designs)	AGCCACGCACCTCCTCCCCGGGG	SHD	ENSG00000105251	1.62220793410291	[]	[]	6	hSpCas9	negative selection	3458656
4280165	4280188	19	-	26780180	HT29	viability (Avana library 4 designs)	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	0.0748462143535903	[]	[]	0	hSpCas9	negative selection	3458657
4282896	4282919	19	-	26780180	HT29	viability (Avana library 4 designs)	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	0.387974199496917	[]	[]	1	hSpCas9	negative selection	3458658
4280165	4280188	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	5.69239449450444	[]	[]	8	hSpCas9	negative selection	3558202
4282896	4282919	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	2.57479922568578	[]	[]	4	hSpCas9	negative selection	3558203
4280258	4280281	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AACCATACTTGGCATCTCCGGGG	SHD	ENSG00000105251	-2.88151235947026	[]	[]	-3	hSpCas9	negative selection	3558204
4280348	4280371	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGCCACGCACCTCCTCCCCGGGG	SHD	ENSG00000105251	0.565701580394471	[]	[]	0	hSpCas9	negative selection	3558205
4282897	4282920	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGAGGCTGAGCATCAAAGGG	SHD	ENSG00000105251	0.399161115691543	[]	[]	0	hSpCas9	negative selection	3558206
4280231	4280254	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGAGTCCCCAGGGCCCGCGGGG	SHD	ENSG00000105251	5.13649506852825	[]	[]	8	hSpCas9	negative selection	3558207
4280165	4280188	19	-	26780180	A375	viability (Avana lentiGuide)	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	-1.28093385172195	[]	[]	-2	hSpCas9	negative selection	3666861
4282896	4282919	19	-	26780180	A375	viability (Avana lentiGuide)	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-2.00610297747305	[]	[]	-3	hSpCas9	negative selection	3666862
4280258	4280281	19	-	26780180	A375	viability (Avana lentiGuide)	AACCATACTTGGCATCTCCGGGG	SHD	ENSG00000105251	6.7817986445254	[]	[]	5	hSpCas9	negative selection	3666863
4280348	4280371	19	-	26780180	A375	viability (Avana lentiGuide)	AGCCACGCACCTCCTCCCCGGGG	SHD	ENSG00000105251	15.2834109187424	[]	[]	8	hSpCas9	negative selection	3666864
4282897	4282920	19	-	26780180	A375	viability (Avana lentiGuide)	GGATGAGGCTGAGCATCAAAGGG	SHD	ENSG00000105251	0.818957946216182	[]	[]	1	hSpCas9	negative selection	3666865
4280231	4280254	19	-	26780180	A375	viability (Avana lentiGuide)	TGGAGTCCCCAGGGCCCGCGGGG	SHD	ENSG00000105251	11.7543803935665	[]	[]	7	hSpCas9	negative selection	3666866
4280165	4280188	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	0.1683931761673953	[5]	[6,5]	4	hSpCas9	positive selection	3775468
4282896	4282919	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.05432577422736884	[5]	[5,4]	-1	hSpCas9	positive selection	3775469
4280258	4280281	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACCATACTTGGCATCTCCGGGG	SHD	ENSG00000105251	0.008131211008102879	[3]	[3,3]	0	hSpCas9	positive selection	3775470
4280348	4280371	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCCACGCACCTCCTCCCCGGGG	SHD	ENSG00000105251	0.09873303664262736	[5]	[6,4]	2	hSpCas9	positive selection	3775471
4282897	4282920	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGAGGCTGAGCATCAAAGGG	SHD	ENSG00000105251	0.03238151771733616	[5]	[6,5]	0	hSpCas9	positive selection	3775472
4280231	4280254	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGAGTCCCCAGGGCCCGCGGGG	SHD	ENSG00000105251	0.17335787184116602	[4]	[4,4]	5	hSpCas9	positive selection	3775473
4280165	4280188	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	-0.01509539622876438	[6]	[4,6]	0	hSpCas9	positive selection	3884075
4282896	4282919	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.5770149709460862	[6]	[2,3]	-6	hSpCas9	positive selection	3884076
4280258	4280281	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACCATACTTGGCATCTCCGGGG	SHD	ENSG00000105251	-1.482705591800476	[3]	[0,0]	-9	hSpCas9	positive selection	3884077
4280348	4280371	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCCACGCACCTCCTCCCCGGGG	SHD	ENSG00000105251	-0.24338994660278063	[6]	[4,3]	-3	hSpCas9	positive selection	3884078
4282897	4282920	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGAGGCTGAGCATCAAAGGG	SHD	ENSG00000105251	0.2735870846132693	[5]	[6,5]	7	hSpCas9	positive selection	3884079
4280231	4280254	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGAGTCCCCAGGGCCCGCGGGG	SHD	ENSG00000105251	-0.5032882335170054	[4]	[1,3]	-6	hSpCas9	positive selection	3884080
4282959	4282982	19	-	26780180	A375	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.270014480537725	[]	[]	0	hSpCas9	negative selection	3994130
4280162	4280185	19	+	26780180	A375	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	1.35453811929857	[]	[]	7	hSpCas9	negative selection	3994131
4283047	4283070	19	+	26780180	A375	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	0.929672675900872	[]	[]	4	hSpCas9	negative selection	3994132
4283076	4283099	19	+	26780180	A375	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	1.09089817492645	[]	[]	5	hSpCas9	negative selection	3994133
4280140	4280163	19	-	26780180	A375	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.33890303137656	[]	[]	0	hSpCas9	negative selection	3994134
4282943	4282966	19	+	26780180	A375	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.711571632461852	[]	[]	2	hSpCas9	negative selection	3994135
4282959	4282982	19	-	26780180	HT29	viability (GeCKOv2 library)	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	1.35477289374374	[]	[]	7	hSpCas9	negative selection	4102096
4280162	4280185	19	+	26780180	HT29	viability (GeCKOv2 library)	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	1.05400410337311	[]	[]	5	hSpCas9	negative selection	4102097
4283047	4283070	19	+	26780180	HT29	viability (GeCKOv2 library)	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	0.701322469430556	[]	[]	2	hSpCas9	negative selection	4102098
4283076	4283099	19	+	26780180	HT29	viability (GeCKOv2 library)	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	0.341688952990068	[]	[]	0	hSpCas9	negative selection	4102099
4280140	4280163	19	-	26780180	HT29	viability (GeCKOv2 library)	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.70597205331556	[]	[]	2	hSpCas9	negative selection	4102100
4282943	4282966	19	+	26780180	HT29	viability (GeCKOv2 library)	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	1.23866037107746	[]	[]	6	hSpCas9	negative selection	4102101
4280137	4280160	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACACCGAGAGCGACATCCTGAGG	SHD	ENSG00000105251	0.10983157734971222	[4]	[3,3]	3	hSpCas9	positive selection	4170021
4280165	4280188	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	-0.41070610802518526	[3]	[1,0]	-8	hSpCas9	positive selection	4170022
4282943	4282966	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.060525246483809	[4]	[3,2]	1	hSpCas9	positive selection	4170023
4280137	4280160	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACACCGAGAGCGACATCCTGAGG	SHD	ENSG00000105251	1.373740875044235	[4]	[2,3,5,5]	9	hSpCas9	positive selection	4234043
4280165	4280188	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTCCAGGTTCTTCTGCGCGCGG	SHD	ENSG00000105251	1.000578077272358	[3]	[2,4,0,3]	7	hSpCas9	positive selection	4234044
4282943	4282966	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.5121076883484514	[4]	[0,1,1,0]	-7	hSpCas9	positive selection	4234045
4283076	4283099	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	0.2408466519743347	[4]	[4,3]	5	hSpCas9	positive selection	4297648
4282943	4282966	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.2712222035464904	[3]	[3,2]	5	hSpCas9	positive selection	4297649
4280140	4280163	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.38149859775707784	[1]	[2,0]	7	hSpCas9	positive selection	4297650
4280162	4280185	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	-0.022568391263373566	[3]	[2,2]	0	hSpCas9	positive selection	4361902
4282959	4282982	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.13136624864663496	[3]	[3,2]	2	hSpCas9	positive selection	4361903
4283047	4283070	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.08836337022437275	[3]	[2,1]	-2	hSpCas9	positive selection	4361904
4280195	4280217	19	-	27760321	OCIAML3	viability	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	0.7503228683444819	[677,647]	[879,864]	8	hSpCas9	negative selection	4438785
4280283	4280305	19	+	27760321	OCIAML3	viability	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	0.3542572577989195	[818,727]	[683,886]	4	hSpCas9	negative selection	4438786
4282924	4282946	19	+	27760321	OCIAML3	viability	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4438787
4282945	4282967	19	+	27760321	OCIAML3	viability	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.28771411402171265	[513,388]	[315,572]	3	hSpCas9	negative selection	4438788
4283049	4283071	19	+	27760321	OCIAML3	viability	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	-0.6343373853386296	[535,452]	[216,288]	-6	hSpCas9	negative selection	4438789
4280195	4280217	19	-	27760321	OCIAML2	viability	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	0.3253863397492046	[677,647]	[527,863]	4	hSpCas9	negative selection	4522248
4280283	4280305	19	+	27760321	OCIAML2	viability	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	0.09259211749683893	[818,727]	[556,809]	1	hSpCas9	negative selection	4522249
4282924	4282946	19	+	27760321	OCIAML2	viability	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4522250
4282945	4282967	19	+	27760321	OCIAML2	viability	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.0515568341605035	[513,388]	[305,466]	0	hSpCas9	negative selection	4522251
4283049	4283071	19	+	27760321	OCIAML2	viability	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	0.39937170377914	[535,452]	[504,552]	5	hSpCas9	negative selection	4522252
4280195	4280217	19	-	27760321	MV411	viability	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	0.4070767026699288	[677,647]	[303,996]	3	hSpCas9	negative selection	4605711
4280283	4280305	19	+	27760321	MV411	viability	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	0.29321857374355365	[818,727]	[508,797]	2	hSpCas9	negative selection	4605712
4282924	4282946	19	+	27760321	MV411	viability	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	6.512209238340681	[0,0]	[99,0]	10	hSpCas9	negative selection	4605713
4282945	4282967	19	+	27760321	MV411	viability	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	1.1201304175647753	[513,388]	[643,639]	7	hSpCas9	negative selection	4605714
4283049	4283071	19	+	27760321	MV411	viability	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	-0.008229628118133325	[535,452]	[196,512]	0	hSpCas9	negative selection	4605715
4280195	4280217	19	-	27760321	HL60	viability	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	0.36378791694335966	[677,647]	[578,823]	4	hSpCas9	negative selection	4689174
4280283	4280305	19	+	27760321	HL60	viability	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	0.4266872903401614	[818,727]	[797,900]	5	hSpCas9	negative selection	4689175
4282924	4282946	19	+	27760321	HL60	viability	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4689176
4282945	4282967	19	+	27760321	HL60	viability	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.2708638077037047	[513,388]	[321,567]	3	hSpCas9	negative selection	4689177
4283049	4283071	19	+	27760321	HL60	viability	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	-0.04631376105311692	[535,452]	[431,344]	0	hSpCas9	negative selection	4689178
4280195	4280217	19	-	27760321	HT1080	viability	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	0.005002178311847905	[647,505]	[191,272]	0	hSpCas9	negative selection	4772637
4280283	4280305	19	+	27760321	HT1080	viability	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	0.6721020917790714	[727,567]	[280,553]	3	hSpCas9	negative selection	4772638
4282924	4282946	19	+	27760321	HT1080	viability	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4772639
4282945	4282967	19	+	27760321	HT1080	viability	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.6841579755414413	[388,303]	[143,306]	3	hSpCas9	negative selection	4772640
4283049	4283071	19	+	27760321	HT1080	viability	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	1.288230811239578	[452,353]	[415,366]	7	hSpCas9	negative selection	4772641
4280195	4280217	19	-	27760321	HT29	viability after 7 days	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	-0.22399940482488473	[647,505]	[908,631,409]	-3	hSpCas9	negative selection	4856100
4280283	4280305	19	+	27760321	HT29	viability after 7 days	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	0.3022516261481971	[727,567]	[1384,864,885]	4	hSpCas9	negative selection	4856101
4282924	4282946	19	+	27760321	HT29	viability after 7 days	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4856102
4282945	4282967	19	+	27760321	HT29	viability after 7 days	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.6920760134402185	[388,303]	[729,1032,406]	9	hSpCas9	negative selection	4856103
4283049	4283071	19	+	27760321	HT29	viability after 7 days	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	0.6057673463594401	[452,353]	[1185,765,481]	8	hSpCas9	negative selection	4856104
4280195	4280217	19	-	27760321	HT29	viability after 25 days	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	0.1643045277621249	[647,505]	[515,671,1076]	1	hSpCas9	negative selection	4939563
4280283	4280305	19	+	27760321	HT29	viability after 25 days	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	0.8937975947051331	[727,567]	[1503,1200,1416]	9	hSpCas9	negative selection	4939564
4282924	4282946	19	+	27760321	HT29	viability after 25 days	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4939565
4282945	4282967	19	+	27760321	HT29	viability after 25 days	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.8235458339082694	[388,303]	[464,901,754]	8	hSpCas9	negative selection	4939566
4283049	4283071	19	+	27760321	HT29	viability after 25 days	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	0.7136577990029114	[452,353]	[821,586,865]	7	hSpCas9	negative selection	4939567
4280195	4280217	19	-	27760321	HT29	viability after 22 days	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	0.04031884662956897	[647,505]	[513,707,841]	0	hSpCas9	negative selection	5023026
4280283	4280305	19	+	27760321	HT29	viability after 22 days	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	1.0604785231916876	[727,567]	[1999,1129,1544]	9	hSpCas9	negative selection	5023027
4282924	4282946	19	+	27760321	HT29	viability after 22 days	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5023028
4282945	4282967	19	+	27760321	HT29	viability after 22 days	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.8685190027026624	[388,303]	[856,688,643]	8	hSpCas9	negative selection	5023029
4283049	4283071	19	+	27760321	HT29	viability after 22 days	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	0.6719636107400339	[452,353]	[1010,518,691]	7	hSpCas9	negative selection	5023030
4280195	4280217	19	-	27760321	HT29	viability after 19 days	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	0.1440571340037874	[647,505]	[583,698,882]	1	hSpCas9	negative selection	5106489
4280283	4280305	19	+	27760321	HT29	viability after 19 days	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	0.5689743935736318	[727,567]	[1856,615,910]	6	hSpCas9	negative selection	5106490
4282924	4282946	19	+	27760321	HT29	viability after 19 days	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5106491
4282945	4282967	19	+	27760321	HT29	viability after 19 days	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.8341202613332828	[388,303]	[879,649,610]	8	hSpCas9	negative selection	5106492
4283049	4283071	19	+	27760321	HT29	viability after 19 days	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	0.4560628966864062	[452,353]	[738,860,321]	4	hSpCas9	negative selection	5106493
4280195	4280217	19	-	27760321	HT29	viability after 16 days	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	0.4556004122444427	[647,505]	[714,834,1090]	5	hSpCas9	negative selection	5189952
4280283	4280305	19	+	27760321	HT29	viability after 16 days	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	0.8238581770233029	[727,567]	[1717,928,1252]	8	hSpCas9	negative selection	5189953
4282924	4282946	19	+	27760321	HT29	viability after 16 days	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5189954
4282945	4282967	19	+	27760321	HT29	viability after 16 days	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.9493619927435214	[388,303]	[693,735,810]	9	hSpCas9	negative selection	5189955
4283049	4283071	19	+	27760321	HT29	viability after 16 days	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	0.823977699492158	[452,353]	[810,633,957]	8	hSpCas9	negative selection	5189956
4280195	4280217	19	-	27760321	HT29	viability after 13 days	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	-0.005245553331877706	[647,505]	[601,766,633]	0	hSpCas9	negative selection	5273415
4280283	4280305	19	+	27760321	HT29	viability after 13 days	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	0.35783787560768254	[727,567]	[1074,857,956]	4	hSpCas9	negative selection	5273416
4282924	4282946	19	+	27760321	HT29	viability after 13 days	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5273417
4282945	4282967	19	+	27760321	HT29	viability after 13 days	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.871335438789605	[388,303]	[634,846,724]	9	hSpCas9	negative selection	5273418
4283049	4283071	19	+	27760321	HT29	viability after 13 days	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	0.3642995757201388	[452,353]	[767,481,559]	4	hSpCas9	negative selection	5273419
4280195	4280217	19	-	27760321	HT29	viability after 10 days	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	0.30813285407347313	[647,505]	[879,1101,703]	4	hSpCas9	negative selection	5356878
4280283	4280305	19	+	27760321	HT29	viability after 10 days	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	0.27696380164729795	[727,567]	[769,1080,1089]	4	hSpCas9	negative selection	5356879
4282924	4282946	19	+	27760321	HT29	viability after 10 days	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5356880
4282945	4282967	19	+	27760321	HT29	viability after 10 days	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.7017390976226318	[388,303]	[525,682,896]	8	hSpCas9	negative selection	5356881
4283049	4283071	19	+	27760321	HT29	viability after 10 days	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	0.39980641236867454	[452,353]	[563,828,606]	5	hSpCas9	negative selection	5356882
4280195	4280217	19	-	27760321	MOLM13	viability	GCTCTCCGCGTCCTCATAGGGG	SHD	ENSG00000105251	2.0897652579365857	[677,647]	[3173,249]	9	hSpCas9	negative selection	5440341
4280283	4280305	19	+	27760321	MOLM13	viability	CCCAAGCACCGGCTCATCAAGG	SHD	ENSG00000105251	1.0041312227912709	[818,727]	[1008,758]	7	hSpCas9	negative selection	5440342
4282924	4282946	19	+	27760321	MOLM13	viability	CCCCCGGATGATGGGTACATGG	SHD	ENSG00000105251	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5440343
4282945	4282967	19	+	27760321	MOLM13	viability	GAGCCCTACGATGCCCAATGGG	SHD	ENSG00000105251	0.3765671446360203	[513,388]	[71,545]	2	hSpCas9	negative selection	5440344
4283049	4283071	19	+	27760321	MOLM13	viability	CCTAGAACTTCCCGGCAGAGGG	SHD	ENSG00000105251	1.1481124014649084	[535,452]	[856,410]	7	hSpCas9	negative selection	5440345
4279741	4279764	19	-	27661255	K562	viability	GCTAGGGCGAGGGGCATCCGCGG	SHD	ENSG00000105251	-0.24632335713101156	[972,1083]	[653,722]	-6	dCas9-KRAB	negative selection	5510899
4283076	4283099	19	+	27260156	BXPC3	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.19790867302191995	[1100]	[1013,951,906,1152]	-4	hSpCas9	negative selection	5570108
4282943	4282966	19	+	27260156	BXPC3	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.07141614248234399	[474]	[423,487,402,589]	-2	hSpCas9	negative selection	5570109
4280140	4280163	19	-	27260156	BXPC3	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.8890636595828723	[97]	[200,126,211,224]	9	hSpCas9	negative selection	5570110
4280162	4280185	19	+	27260156	BXPC3	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	-0.08503549829473267	[602]	[577,563,622,614]	-2	hSpCas9	negative selection	5634362
4282959	4282982	19	-	27260156	BXPC3	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.01570815004195414	[692]	[771,659,734,688]	0	hSpCas9	negative selection	5634363
4283047	4283070	19	+	27260156	BXPC3	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.16102943977591588	[553]	[520,466,517,571]	-4	hSpCas9	negative selection	5634364
4283076	4283099	19	+	27260156	A673	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.08778739661319168	[1100]	[1433,1200,1140,1219]	-2	hSpCas9	negative selection	5691359
4282943	4282966	19	+	27260156	A673	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.15883338698745836	[474]	[910,593,455,617]	4	hSpCas9	negative selection	5691360
4280140	4280163	19	-	27260156	A673	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.5145813616765804	[97]	[231,144,154,146]	9	hSpCas9	negative selection	5691361
4280162	4280185	19	+	27260156	A673	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.16785529356908524	[602]	[706,727,921,887]	4	hSpCas9	negative selection	5755613
4282959	4282982	19	-	27260156	A673	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.0912092843126564	[692]	[1092,691,837,953]	2	hSpCas9	negative selection	5755614
4283047	4283070	19	+	27260156	A673	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	0.016826703558496275	[553]	[653,515,745,781]	0	hSpCas9	negative selection	5755615
4283076	4283099	19	+	27260156	A375	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.03430162216570354	[1100]	[1391,1363,1159,1132]	0	hSpCas9	negative selection	5812610
4282943	4282966	19	+	27260156	A375	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.19756026897772844	[474]	[515,370,566,465]	-3	hSpCas9	negative selection	5812611
4280140	4280163	19	-	27260156	A375	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.3359725147013424	[97]	[170,157,138,114]	5	hSpCas9	negative selection	5812612
4280162	4280185	19	+	27260156	A375	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	-0.0727897460892985	[602]	[707,600,773,592]	-1	hSpCas9	negative selection	5876864
4282959	4282982	19	-	27260156	A375	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.027223076424328196	[692]	[948,988,539,839]	0	hSpCas9	negative selection	5876865
4283047	4283070	19	+	27260156	A375	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.6893470599889256	[553]	[324,480,387,417]	-7	hSpCas9	negative selection	5876866
4283076	4283099	19	+	27260156	COLO741	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.005693167858658255	[1100]	[1533,1394,1290]	0	hSpCas9	negative selection	5933861
4282943	4282966	19	+	27260156	COLO741	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.3315449174024761	[474]	[797,921,585]	7	hSpCas9	negative selection	5933862
4280140	4280163	19	-	27260156	COLO741	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.8583661658811395	[97]	[247,314,126]	9	hSpCas9	negative selection	5933863
4280162	4280185	19	+	27260156	COLO741	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	-0.01733098727068144	[602]	[758,637,875]	0	hSpCas9	negative selection	5998115
4282959	4282982	19	-	27260156	COLO741	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.18147610793039903	[692]	[918,1133,953]	4	hSpCas9	negative selection	5998116
4283047	4283070	19	+	27260156	COLO741	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.027795271576051078	[553]	[821,644,629]	0	hSpCas9	negative selection	5998117
4283076	4283099	19	+	27260156	CAL120	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	0.007388069612896286	[1100]	[1196,1269,1631]	0	hSpCas9	negative selection	6055112
4282943	4282966	19	+	27260156	CAL120	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.31268446872961814	[474]	[792,741,676]	5	hSpCas9	negative selection	6055113
4280140	4280163	19	-	27260156	CAL120	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	1.524589236459418	[97]	[610,265,216]	9	hSpCas9	negative selection	6055114
4280162	4280185	19	+	27260156	CAL120	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.14824001828687283	[602]	[1117,897,526]	2	hSpCas9	negative selection	6119366
4282959	4282982	19	-	27260156	CAL120	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.1829015391635399	[692]	[868,1137,913]	2	hSpCas9	negative selection	6119367
4283047	4283070	19	+	27260156	CAL120	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.5317981740525545	[553]	[495,447,488]	-6	hSpCas9	negative selection	6119368
4283076	4283099	19	+	27260156	CADOES1	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.4746710864955834	[1100]	[626,711,840,768]	-7	hSpCas9	negative selection	6176363
4282943	4282966	19	+	27260156	CADOES1	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.17904662537606877	[474]	[513,431,513,541]	3	hSpCas9	negative selection	6176364
4280140	4280163	19	-	27260156	CADOES1	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.39562651954762584	[97]	[131,84,129,132]	6	hSpCas9	negative selection	6176365
4280162	4280185	19	+	27260156	CADOES1	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	-0.10889832989553294	[602]	[609,556,445,464]	-2	hSpCas9	negative selection	6240617
4282959	4282982	19	-	27260156	CADOES1	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.06685219955570909	[692]	[621,559,618,661]	-1	hSpCas9	negative selection	6240618
4283047	4283070	19	+	27260156	CADOES1	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.3205114640012573	[553]	[390,369,409,481]	-5	hSpCas9	negative selection	6240619
4283076	4283099	19	+	27260156	EWS502	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.3443747400785758	[1100]	[942,780,802,1161]	-5	hSpCas9	negative selection	6297614
4282943	4282966	19	+	27260156	EWS502	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.05562386409878251	[474]	[392,455,654,441]	-1	hSpCas9	negative selection	6297615
4280140	4280163	19	-	27260156	EWS502	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	1.146436286932346	[97]	[161,292,206,263]	9	hSpCas9	negative selection	6297616
4280162	4280185	19	+	27260156	EWS502	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.09640795704906169	[602]	[593,570,673,921]	1	hSpCas9	negative selection	6361868
4282959	4282982	19	-	27260156	EWS502	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.10324609787607653	[692]	[828,815,752,742]	1	hSpCas9	negative selection	6361869
4283047	4283070	19	+	27260156	EWS502	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.7278898493344178	[553]	[295,359,307,465]	-8	hSpCas9	negative selection	6361870
4283076	4283099	19	+	27260156	EW8	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.2802816309548898	[1100]	[945,815,609,609]	-5	hSpCas9	negative selection	6418865
4282943	4282966	19	+	27260156	EW8	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.13344874891723632	[474]	[393,512,315,479]	2	hSpCas9	negative selection	6418866
4280140	4280163	19	-	27260156	EW8	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.5567304770228088	[97]	[49,89,123,193]	8	hSpCas9	negative selection	6418867
4280162	4280185	19	+	27260156	EW8	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.10231001226954883	[602]	[557,453,554,527]	1	hSpCas9	negative selection	6483119
4282959	4282982	19	-	27260156	EW8	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.004420337171967992	[692]	[522,566,492,661]	0	hSpCas9	negative selection	6483120
4283047	4283070	19	+	27260156	EW8	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.4720597925082071	[553]	[371,301,251,384]	-7	hSpCas9	negative selection	6483121
4283076	4283099	19	+	27260156	CORL105	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.27567071658664866	[1100]	[1058,894,1214,1115]	-5	hSpCas9	negative selection	6540116
4282943	4282966	19	+	27260156	CORL105	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.2707498188843021	[474]	[661,625,860,564]	5	hSpCas9	negative selection	6540117
4280140	4280163	19	-	27260156	CORL105	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.6972361430880705	[97]	[151,116,249,234]	9	hSpCas9	negative selection	6540118
4280162	4280185	19	+	27260156	CORL105	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.11643103081211398	[602]	[752,766,719,812]	2	hSpCas9	negative selection	6604370
4282959	4282982	19	-	27260156	CORL105	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.03176189896490211	[692]	[663,711,1146,703]	0	hSpCas9	negative selection	6604371
4283047	4283070	19	+	27260156	CORL105	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.05861052463916075	[553]	[745,453,615,680]	-1	hSpCas9	negative selection	6604372
4283076	4283099	19	+	27260156	HS294T	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	0.14501221662969233	[1100]	[281,525,537,567]	2	hSpCas9	negative selection	6661367
4282943	4282966	19	+	27260156	HS294T	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.1918448957256755	[474]	[178,137,161,162]	-3	hSpCas9	negative selection	6661368
4280140	4280163	19	-	27260156	HS294T	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	-0.234952037237258	[97]	[24,22,47,33]	-3	hSpCas9	negative selection	6661369
4280162	4280185	19	+	27260156	HS294T	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.2648910443924052	[602]	[357,197,242,322]	3	hSpCas9	negative selection	6725621
4282959	4282982	19	-	27260156	HS294T	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.041845265838050594	[692]	[184,276,219,385]	0	hSpCas9	negative selection	6725622
4283047	4283070	19	+	27260156	HS294T	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.10257792864602228	[553]	[186,193,241,170]	-1	hSpCas9	negative selection	6725623
4283076	4283099	19	+	27260156	HCC44	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.0006316422681811318	[1100]	[1299,1279,1175,1201]	0	hSpCas9	negative selection	6782618
4282943	4282966	19	+	27260156	HCC44	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.22040011911820498	[474]	[722,443,542,802]	3	hSpCas9	negative selection	6782619
4280140	4280163	19	-	27260156	HCC44	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.6477460028215969	[97]	[134,115,340,135]	9	hSpCas9	negative selection	6782620
4280162	4280185	19	+	27260156	HCC44	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.26700855224505915	[602]	[863,668,733,1012]	4	hSpCas9	negative selection	6846872
4282959	4282982	19	-	27260156	HCC44	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.3580960235480779	[692]	[835,1154,903,1058]	6	hSpCas9	negative selection	6846873
4283047	4283070	19	+	27260156	HCC44	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	0.1278976019645169	[553]	[747,475,860,712]	2	hSpCas9	negative selection	6846874
4283076	4283099	19	+	27260156	G402	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.6695281652643696	[1100]	[710,960,766,919]	-7	hSpCas9	negative selection	6903869
4282943	4282966	19	+	27260156	G402	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.03196449115996994	[474]	[540,781,677,286]	0	hSpCas9	negative selection	6903870
4280140	4280163	19	-	27260156	G402	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.8388694489478552	[97]	[426,77,124,245]	9	hSpCas9	negative selection	6903871
4280162	4280185	19	+	27260156	G402	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.19190701342363514	[602]	[907,971,994,516]	2	hSpCas9	negative selection	6968123
4282959	4282982	19	-	27260156	G402	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.24558595492898389	[692]	[536,761,887,643]	-3	hSpCas9	negative selection	6968124
4283047	4283070	19	+	27260156	G402	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	0.09234491265523212	[553]	[805,1136,476,506]	1	hSpCas9	negative selection	6968125
4283076	4283099	19	+	27260156	L33	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.0015916060460021697	[1100]	[1187,409,737,1034]	0	hSpCas9	negative selection	7025120
4282943	4282966	19	+	27260156	L33	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.45735859315080574	[474]	[603,237,461,689]	8	hSpCas9	negative selection	7025121
4280140	4280163	19	-	27260156	L33	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.838568076579866	[97]	[159,60,132,180]	9	hSpCas9	negative selection	7025122
4280162	4280185	19	+	27260156	L33	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.22006222440100875	[602]	[787,306,471,520]	5	hSpCas9	negative selection	7089374
4282959	4282982	19	-	27260156	L33	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.013624343832261188	[692]	[585,310,431,767]	0	hSpCas9	negative selection	7089375
4283047	4283070	19	+	27260156	L33	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	0.11223274035423028	[553]	[620,232,378,601]	2	hSpCas9	negative selection	7089376
4283076	4283099	19	+	27260156	K562	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.8758601282443947	[1100]	[576,755,363,454]	-7	hSpCas9	negative selection	7146371
4282943	4282966	19	+	27260156	K562	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.24877201088663287	[474]	[463,607,780,187]	3	hSpCas9	negative selection	7146372
4280140	4280163	19	-	27260156	K562	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.8737024262352682	[97]	[127,120,259,126]	9	hSpCas9	negative selection	7146373
4280162	4280185	19	+	27260156	K562	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.1789482324924726	[602]	[491,736,534,648]	2	hSpCas9	negative selection	7210625
4282959	4282982	19	-	27260156	K562	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.30059235225381886	[692]	[1094,736,754,496]	4	hSpCas9	negative selection	7210626
4283047	4283070	19	+	27260156	K562	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.21125038398789917	[553]	[275,660,475,298]	-3	hSpCas9	negative selection	7210627
4283076	4283099	19	+	27260156	HT29	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.09121235189274879	[1100]	[1256,1380,1337,1073]	-2	hSpCas9	negative selection	7267622
4282943	4282966	19	+	27260156	HT29	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.06504815010139421	[474]	[639,668,550,564]	1	hSpCas9	negative selection	7267623
4280140	4280163	19	-	27260156	HT29	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.3740456714558933	[97]	[203,221,125,82]	7	hSpCas9	negative selection	7267624
4280162	4280185	19	+	27260156	HT29	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.08884397156181251	[602]	[901,786,755,688]	1	hSpCas9	negative selection	7331876
4282959	4282982	19	-	27260156	HT29	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.20451561729881995	[692]	[901,903,1098,960]	4	hSpCas9	negative selection	7331877
4283047	4283070	19	+	27260156	HT29	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.2523795631060329	[553]	[645,541,628,457]	-5	hSpCas9	negative selection	7331878
4283076	4283099	19	+	27260156	MHHES1	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.044405447120629216	[1100]	[1621,1214,1125,933]	-1	hSpCas9	negative selection	7388873
4282943	4282966	19	+	27260156	MHHES1	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.37278121863801994	[474]	[824,789,450,708]	6	hSpCas9	negative selection	7388874
4280140	4280163	19	-	27260156	MHHES1	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.5606783906875275	[97]	[262,171,133,104]	8	hSpCas9	negative selection	7388875
4280162	4280185	19	+	27260156	MHHES1	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	-0.1928483276774666	[602]	[538,741,563,538]	-4	hSpCas9	negative selection	7453127
4282959	4282982	19	-	27260156	MHHES1	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.13532388199369638	[692]	[1231,574,1043,629]	2	hSpCas9	negative selection	7453128
4283047	4283070	19	+	27260156	MHHES1	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.31723383626944357	[553]	[586,510,467,448]	-5	hSpCas9	negative selection	7453129
4283076	4283099	19	+	27260156	MEWO	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	0.03203594885306482	[1100]	[1394,957,872]	0	hSpCas9	negative selection	7510124
4282943	4282966	19	+	27260156	MEWO	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.20963120151928233	[474]	[668,433,468]	4	hSpCas9	negative selection	7510125
4280140	4280163	19	-	27260156	MEWO	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.4623189849874705	[97]	[84,110,174]	8	hSpCas9	negative selection	7510126
4280162	4280185	19	+	27260156	MEWO	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	-0.2774293650241037	[602]	[381,482,514]	-6	hSpCas9	negative selection	7574378
4282959	4282982	19	-	27260156	MEWO	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.2833564269487485	[692]	[1189,717,536]	6	hSpCas9	negative selection	7574379
4283047	4283070	19	+	27260156	MEWO	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	0.04181078441007777	[553]	[701,357,573]	0	hSpCas9	negative selection	7574380
4283076	4283099	19	+	27260156	LNCAPCLONEFGC	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	0.0347699349772701	[1100]	[927,858,1320,1034]	0	hSpCas9	negative selection	7631375
4282943	4282966	19	+	27260156	LNCAPCLONEFGC	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.3270610889911734	[474]	[596,341,514,712]	5	hSpCas9	negative selection	7631376
4280140	4280163	19	-	27260156	LNCAPCLONEFGC	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.8007297527069341	[97]	[142,207,193,75]	9	hSpCas9	negative selection	7631377
4280162	4280185	19	+	27260156	LNCAPCLONEFGC	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.24247548309038225	[602]	[636,566,741,657]	4	hSpCas9	negative selection	7695629
4282959	4282982	19	-	27260156	LNCAPCLONEFGC	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.03228020942501164	[692]	[500,635,830,519]	0	hSpCas9	negative selection	7695630
4283047	4283070	19	+	27260156	LNCAPCLONEFGC	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.08465109681623972	[553]	[570,297,571,475]	-1	hSpCas9	negative selection	7695631
4283076	4283099	19	+	27260156	PANC0327	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	0.006232468614200792	[1100]	[1117,901,1293,636]	0	hSpCas9	negative selection	7752626
4282943	4282966	19	+	27260156	PANC0327	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.6117681226188096	[474]	[470,436,528,1153]	8	hSpCas9	negative selection	7752627
4280140	4280163	19	-	27260156	PANC0327	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.7431378684848915	[97]	[89,116,192,181]	9	hSpCas9	negative selection	7752628
4280162	4280185	19	+	27260156	PANC0327	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	-0.18133491052291417	[602]	[464,329,450,660]	-3	hSpCas9	negative selection	7816880
4282959	4282982	19	-	27260156	PANC0327	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	1.2335786705465472	[692]	[1110,3133,762,535]	9	hSpCas9	negative selection	7816881
4283047	4283070	19	+	27260156	PANC0327	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.029611328369136353	[553]	[527,513,459,425]	0	hSpCas9	negative selection	7816882
4283076	4283099	19	+	27260156	NCIH2009	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.056436124411121336	[1100]	[1745,1312,1431]	0	hSpCas9	negative selection	7873877
4282943	4282966	19	+	27260156	NCIH2009	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.3762711337760987	[474]	[987,793,826]	5	hSpCas9	negative selection	7873878
4280140	4280163	19	-	27260156	NCIH2009	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.8214179569662159	[97]	[327,212,201]	9	hSpCas9	negative selection	7873879
4280162	4280185	19	+	27260156	NCIH2009	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.02739803860013601	[602]	[1241,650,760]	0	hSpCas9	negative selection	7938131
4282959	4282982	19	-	27260156	NCIH2009	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.09970158794608852	[692]	[1105,998,1019]	1	hSpCas9	negative selection	7938132
4283047	4283070	19	+	27260156	NCIH2009	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	0.011411996876540098	[553]	[600,877,822]	0	hSpCas9	negative selection	7938133
4283076	4283099	19	+	27260156	NCIH1373	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.06442175009372741	[1100]	[1257,880,972,441]	0	hSpCas9	negative selection	7995128
4282943	4282966	19	+	27260156	NCIH1373	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.2752988829080317	[474]	[902,773,262,175]	2	hSpCas9	negative selection	7995129
4280140	4280163	19	-	27260156	NCIH1373	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	1.026925069901903	[97]	[278,127,129,101]	9	hSpCas9	negative selection	7995130
4280162	4280185	19	+	27260156	NCIH1373	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.23380757573608246	[602]	[925,706,825,194]	2	hSpCas9	negative selection	8059382
4282959	4282982	19	-	27260156	NCIH1373	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.2876091470127386	[692]	[1491,446,436,79]	-3	hSpCas9	negative selection	8059383
4283047	4283070	19	+	27260156	NCIH1373	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.11941852945510943	[553]	[562,357,419,260]	-1	hSpCas9	negative selection	8059384
4283076	4283099	19	+	27260156	PATU8902	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.01914102555748598	[1100]	[1965,1072,1560,1407]	0	hSpCas9	negative selection	8116379
4282943	4282966	19	+	27260156	PATU8902	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.3694219995356361	[474]	[775,865,960,771]	4	hSpCas9	negative selection	8116380
4280140	4280163	19	-	27260156	PATU8902	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	1.8238437743018532	[97]	[475,728,141,696]	9	hSpCas9	negative selection	8116381
4280162	4280185	19	+	27260156	PATU8902	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.4500729315321015	[602]	[1164,954,646,2049]	4	hSpCas9	negative selection	8180633
4282959	4282982	19	-	27260156	PATU8902	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.01807163994600325	[692]	[1729,799,580,869]	0	hSpCas9	negative selection	8180634
4283047	4283070	19	+	27260156	PATU8902	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.11812975457643529	[553]	[1385,639,303,589]	-1	hSpCas9	negative selection	8180635
4283076	4283099	19	+	27260156	PANC1	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.012617218728868451	[1100]	[800,1155,877,944]	0	hSpCas9	negative selection	8237630
4282943	4282966	19	+	27260156	PANC1	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.037410285100902746	[474]	[360,581,439,333]	0	hSpCas9	negative selection	8237631
4280140	4280163	19	-	27260156	PANC1	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.683924212125067	[97]	[147,71,119,177]	9	hSpCas9	negative selection	8237632
4280162	4280185	19	+	27260156	PANC1	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.043858098451105554	[602]	[602,582,465,489]	0	hSpCas9	negative selection	8301884
4282959	4282982	19	-	27260156	PANC1	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.16295192346100662	[692]	[496,1027,702,527]	2	hSpCas9	negative selection	8301885
4283047	4283070	19	+	27260156	PANC1	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	0.010358537433482445	[553]	[448,722,476,334]	0	hSpCas9	negative selection	8301886
4283076	4283099	19	+	27260156	PANC0813	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.14622781179796118	[1100]	[1345,1006,1286,1055]	-2	hSpCas9	negative selection	8358881
4282943	4282966	19	+	27260156	PANC0813	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.483354179640177	[474]	[879,724,933,599]	7	hSpCas9	negative selection	8358882
4280140	4280163	19	-	27260156	PANC0813	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.6208454296819206	[97]	[230,211,154,117]	8	hSpCas9	negative selection	8358883
4280162	4280185	19	+	27260156	PANC0813	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.19275484572531998	[602]	[767,646,818,988]	3	hSpCas9	negative selection	8423135
4282959	4282982	19	-	27260156	PANC0813	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.20914986384191936	[692]	[602,920,758,532]	-3	hSpCas9	negative selection	8423136
4283047	4283070	19	+	27260156	PANC0813	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	0.33612953754445973	[553]	[571,1164,912,622]	5	hSpCas9	negative selection	8423137
4283076	4283099	19	+	27260156	RDES	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.21880383148203775	[1100]	[1002,982,993,1410]	-4	hSpCas9	negative selection	8480132
4282943	4282966	19	+	27260156	RDES	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.17279965682461434	[474]	[499,650,655,667]	3	hSpCas9	negative selection	8480133
4280140	4280163	19	-	27260156	RDES	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.5894899820649058	[97]	[146,206,157,159]	8	hSpCas9	negative selection	8480134
4280162	4280185	19	+	27260156	RDES	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.1813251517378437	[602]	[599,653,736,1254]	3	hSpCas9	negative selection	8544386
4282959	4282982	19	-	27260156	RDES	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.010068933352939125	[692]	[681,782,858,906]	0	hSpCas9	negative selection	8544387
4283047	4283070	19	+	27260156	RDES	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.3916444207227001	[553]	[376,427,677,480]	-6	hSpCas9	negative selection	8544388
4283076	4283099	19	+	27260156	PC3	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.08003388047309667	[1100]	[741,983,1517,1117]	-2	hSpCas9	negative selection	8601383
4282943	4282966	19	+	27260156	PC3	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.4214430088192923	[474]	[361,727,819,759]	8	hSpCas9	negative selection	8601384
4280140	4280163	19	-	27260156	PC3	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.45636269054469647	[97]	[96,125,180,152]	8	hSpCas9	negative selection	8601385
4280162	4280185	19	+	27260156	PC3	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.0763830284139217	[602]	[520,549,777,720]	1	hSpCas9	negative selection	8665637
4282959	4282982	19	-	27260156	PC3	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.15343044824284657	[692]	[537,659,1406,740]	3	hSpCas9	negative selection	8665638
4283047	4283070	19	+	27260156	PC3	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.1454160254483465	[553]	[275,499,899,532]	-3	hSpCas9	negative selection	8665639
4283076	4283099	19	+	27260156	PATU8988T	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	0.04708926322176055	[1100]	[1024,1194,858,1349]	0	hSpCas9	negative selection	8722634
4282943	4282966	19	+	27260156	PATU8988T	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	-0.019380103369147368	[474]	[544,535,301,436]	0	hSpCas9	negative selection	8722635
4280140	4280163	19	-	27260156	PATU8988T	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.7306934710781572	[97]	[126,148,186,164]	9	hSpCas9	negative selection	8722636
4280162	4280185	19	+	27260156	PATU8988T	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.34216418169576357	[602]	[592,804,748,819]	6	hSpCas9	negative selection	8786888
4282959	4282982	19	-	27260156	PATU8988T	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.278882549381106	[692]	[724,1093,600,862]	5	hSpCas9	negative selection	8786889
4283047	4283070	19	+	27260156	PATU8988T	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.13337055415466945	[553]	[484,337,587,528]	-2	hSpCas9	negative selection	8786890
4283076	4283099	19	+	27260156	T47D	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.3759540968278302	[1100]	[1068,976,812,1101]	-7	hSpCas9	negative selection	8843885
4282943	4282966	19	+	27260156	T47D	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.15564656829310994	[474]	[574,536,562,803]	3	hSpCas9	negative selection	8843886
4280140	4280163	19	-	27260156	T47D	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.8085329618321253	[97]	[211,193,202,190]	9	hSpCas9	negative selection	8843887
4280162	4280185	19	+	27260156	T47D	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.08333630361664579	[602]	[767,689,698,827]	1	hSpCas9	negative selection	8908139
4282959	4282982	19	-	27260156	T47D	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.014872374973741387	[692]	[720,653,839,998]	0	hSpCas9	negative selection	8908140
4283047	4283070	19	+	27260156	T47D	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.27990001588974134	[553]	[491,477,528,634]	-6	hSpCas9	negative selection	8908141
4283076	4283099	19	+	27260156	SU8686	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.1853214588909109	[1100]	[998,877,835,1153]	-3	hSpCas9	negative selection	8965136
4282943	4282966	19	+	27260156	SU8686	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.26765993767873975	[474]	[538,470,606,681]	4	hSpCas9	negative selection	8965137
4280140	4280163	19	-	27260156	SU8686	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.5737343329215177	[97]	[111,126,138,216]	8	hSpCas9	negative selection	8965138
4280162	4280185	19	+	27260156	SU8686	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.09726133410716054	[602]	[557,503,662,897]	1	hSpCas9	negative selection	9029390
4282959	4282982	19	-	27260156	SU8686	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.2953078636182792	[692]	[429,618,570,634]	-5	hSpCas9	negative selection	9029391
4283047	4283070	19	+	27260156	SU8686	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.029513946716754058	[553]	[467,432,529,777]	0	hSpCas9	negative selection	9029392
4283076	4283099	19	+	27260156	SKES1	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.20182251792215578	[1100]	[776,1109,926,985]	-4	hSpCas9	negative selection	9086387
4282943	4282966	19	+	27260156	SKES1	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.25293765004701996	[474]	[558,550,492,638]	5	hSpCas9	negative selection	9086388
4280140	4280163	19	-	27260156	SKES1	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.81092631006775	[97]	[188,174,179,145]	9	hSpCas9	negative selection	9086389
4280162	4280185	19	+	27260156	SKES1	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.1042425187454325	[602]	[693,793,563,562]	2	hSpCas9	negative selection	9150641
4282959	4282982	19	-	27260156	SKES1	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.07315600147193546	[692]	[744,918,617,654]	1	hSpCas9	negative selection	9150642
4283047	4283070	19	+	27260156	SKES1	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.12194547974961548	[553]	[570,577,431,467]	-3	hSpCas9	negative selection	9150643
4283076	4283099	19	+	27260156	TOV112D	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.3523906795382654	[1100]	[919,936,781,837]	-6	hSpCas9	negative selection	9207638
4282943	4282966	19	+	27260156	TOV112D	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.23325362935899793	[474]	[531,572,570,560]	4	hSpCas9	negative selection	9207639
4280140	4280163	19	-	27260156	TOV112D	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.8396627691151137	[97]	[126,227,139,214]	9	hSpCas9	negative selection	9207640
4280162	4280185	19	+	27260156	TOV112D	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	-0.4128682156904372	[602]	[475,518,355,479]	-7	hSpCas9	negative selection	9271892
4282959	4282982	19	-	27260156	TOV112D	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	-0.007523440373897294	[692]	[797,815,580,607]	0	hSpCas9	negative selection	9271893
4283047	4283070	19	+	27260156	TOV112D	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.47007625035181577	[553]	[461,543,268,367]	-7	hSpCas9	negative selection	9271894
4283076	4283099	19	+	27260156	TC71	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.27644705942993164	[1100]	[839,947,996,1123]	-6	hSpCas9	negative selection	9328889
4282943	4282966	19	+	27260156	TC71	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.0687018122374573	[474]	[418,590,558,570]	1	hSpCas9	negative selection	9328890
4280140	4280163	19	-	27260156	TC71	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.41570663938481434	[97]	[150,108,135,165]	8	hSpCas9	negative selection	9328891
4280162	4280185	19	+	27260156	TC71	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.12447532801511763	[602]	[640,762,637,784]	3	hSpCas9	negative selection	9393143
4282959	4282982	19	-	27260156	TC71	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.18928601400012268	[692]	[901,819,814,850]	5	hSpCas9	negative selection	9393144
4283047	4283070	19	+	27260156	TC71	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.1083179530048814	[553]	[590,565,490,556]	-3	hSpCas9	negative selection	9393145
4283076	4283099	19	+	27260156	TC32	viability	GCTCTATGACACCCCTTATGAGG	SHD	ENSG00000105251	-0.22161225932498718	[1100]	[870,699,1199,848]	-4	hSpCas9	negative selection	9450140
4282943	4282966	19	+	27260156	TC32	viability	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.20962000914144066	[474]	[512,364,688,556]	4	hSpCas9	negative selection	9450141
4280140	4280163	19	-	27260156	TC32	viability	GGCCCTCAGGATGTCGCTCTCGG	SHD	ENSG00000105251	0.8553161434169063	[97]	[109,142,214,215]	9	hSpCas9	negative selection	9450142
4280162	4280185	19	+	27260156	TC32	viability	CTACCGCGCGCAGAAGAACCTGG	SHD	ENSG00000105251	0.11015715182827351	[602]	[673,393,802,648]	2	hSpCas9	negative selection	9514394
4282959	4282982	19	-	27260156	TC32	viability	ACTCACCACTCATGACCCATTGG	SHD	ENSG00000105251	0.1418927281351663	[692]	[549,679,829,830]	2	hSpCas9	negative selection	9514395
4283047	4283070	19	+	27260156	TC32	viability	CTCCTAGAACTTCCCGGCAGAGG	SHD	ENSG00000105251	-0.1882132281652568	[553]	[479,280,678,463]	-3	hSpCas9	negative selection	9514396
4280312	4280335	19	+	27869803	HPAFII	viability after 27 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.8743879211348415	[400]	[132,99,NaN]	-6	hSpCas9	negative selection	9568109
4282943	4282966	19	+	27869803	HPAFII	viability after 27 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.38984811686100396	[167]	[70,152,NaN]	3	hSpCas9	negative selection	9568125
4283183	4283206	19	+	27869803	HPAFII	viability after 27 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.20992306937423152	[228]	[54,144,NaN]	-1	hSpCas9	negative selection	9568127
4284787	4284810	19	+	27869803	HPAFII	viability after 27 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.5796796893522087	[528]	[274,111,NaN]	-4	hSpCas9	negative selection	9568133
4288350	4288373	19	-	27869803	HPAFII	viability after 27 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	-0.9900378997075844	[180]	[84,16,NaN]	-6	hSpCas9	negative selection	9568134
4290626	4290649	19	-	27869803	HPAFII	viability after 27 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	0.472845622439805	[114]	[42,117,NaN]	4	hSpCas9	negative selection	9568138
4280312	4280335	19	+	27869803	HPAFII	viability after 15 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.40351794118177337	[400]	[495,219,NaN]	-4	hSpCas9	negative selection	9650558
4282943	4282966	19	+	27869803	HPAFII	viability after 15 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.6565664193767548	[167]	[246,307,NaN]	7	hSpCas9	negative selection	9650574
4283183	4283206	19	+	27869803	HPAFII	viability after 15 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.3182308826595164	[228]	[152,224,NaN]	-4	hSpCas9	negative selection	9650576
4284787	4284810	19	+	27869803	HPAFII	viability after 15 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	0.04614020858758261	[528]	[853,420,NaN]	0	hSpCas9	negative selection	9650582
4288350	4288373	19	-	27869803	HPAFII	viability after 15 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	-0.08753545053181322	[180]	[261,133,NaN]	-1	hSpCas9	negative selection	9650583
4290626	4290649	19	-	27869803	HPAFII	viability after 15 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	0.5978798664638598	[114]	[273,132,NaN]	6	hSpCas9	negative selection	9650587
4280312	4280335	19	+	27869803	ASPC1	viability after 36 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.7015677051681634	[1305]	[322,392,157]	-6	hSpCas9	negative selection	9733007
4282943	4282966	19	+	27869803	ASPC1	viability after 36 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.30198622623618565	[399]	[95,259,153]	3	hSpCas9	negative selection	9733023
4283183	4283206	19	+	27869803	ASPC1	viability after 36 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.13817487485245655	[616]	[86,300,288]	1	hSpCas9	negative selection	9733025
4284787	4284810	19	+	27869803	ASPC1	viability after 36 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	0.25683655109444614	[1131]	[836,285,358]	2	hSpCas9	negative selection	9733031
4288350	4288373	19	-	27869803	ASPC1	viability after 36 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.5604479612862208	[296]	[213,131,124]	5	hSpCas9	negative selection	9733032
4290626	4290649	19	-	27869803	ASPC1	viability after 36 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	-0.9418590198705223	[470]	[125,51,82]	-7	hSpCas9	negative selection	9733036
4280312	4280335	19	+	27869803	PATU8988S	viability after 35 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	0.3665690420391199	[838]	[504,365,NaN]	4	hSpCas9	negative selection	9815456
4282943	4282966	19	+	27869803	PATU8988S	viability after 35 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.21620324392964899	[435]	[198,208,NaN]	2	hSpCas9	negative selection	9815472
4283183	4283206	19	+	27869803	PATU8988S	viability after 35 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.010828853894527923	[438]	[168,181,NaN]	0	hSpCas9	negative selection	9815474
4284787	4284810	19	+	27869803	PATU8988S	viability after 35 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	0.01857241263461662	[763]	[393,228,NaN]	0	hSpCas9	negative selection	9815480
4288350	4288373	19	-	27869803	PATU8988S	viability after 35 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.6946701633511541	[229]	[117,181,NaN]	7	hSpCas9	negative selection	9815481
4290626	4290649	19	-	27869803	PATU8988S	viability after 35 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	-2.147696968085081	[351]	[28,34,NaN]	-9	hSpCas9	negative selection	9815485
4280312	4280335	19	+	27869803	PATU8988S	viability after 31 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	0.2851302045716505	[838]	[459,340,NaN]	3	hSpCas9	negative selection	9897905
4282943	4282966	19	+	27869803	PATU8988S	viability after 31 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.0537300415119355	[435]	[223,124,NaN]	0	hSpCas9	negative selection	9897921
4283183	4283206	19	+	27869803	PATU8988S	viability after 31 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.19823684768037234	[438]	[162,248,NaN]	2	hSpCas9	negative selection	9897923
4284787	4284810	19	+	27869803	PATU8988S	viability after 31 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	0.14560431419431097	[763]	[292,392,NaN]	1	hSpCas9	negative selection	9897929
4288350	4288373	19	-	27869803	PATU8988S	viability after 31 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	0.444351650578108	[229]	[82,177,NaN]	5	hSpCas9	negative selection	9897930
4290626	4290649	19	-	27869803	PATU8988S	viability after 31 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	-1.62974263090427	[351]	[25,69,NaN]	-8	hSpCas9	negative selection	9897934
4280312	4280335	19	+	27869803	HPAFII	viability after 35 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.7475909617069905	[400]	[174,59,NaN]	-4	hSpCas9	negative selection	9980354
4282943	4282966	19	+	27869803	HPAFII	viability after 35 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.3789374583069811	[167]	[127,90,NaN]	2	hSpCas9	negative selection	9980370
4283183	4283206	19	+	27869803	HPAFII	viability after 35 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.05972012197975345	[228]	[14,239,NaN]	0	hSpCas9	negative selection	9980372
4284787	4284810	19	+	27869803	HPAFII	viability after 35 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.6788746599925918	[528]	[266,54,NaN]	-4	hSpCas9	negative selection	9980378
4288350	4288373	19	-	27869803	HPAFII	viability after 35 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	-0.9881338851253009	[180]	[80,6,NaN]	-5	hSpCas9	negative selection	9980379
4290626	4290649	19	-	27869803	HPAFII	viability after 35 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	-0.059410809923472474	[114]	[29,84,NaN]	0	hSpCas9	negative selection	9980383
4280312	4280335	19	+	27869803	HPAFII	viability after 31 days	TGCGGATATGGCCAGAGCCAAGG	SHD	ENSG00000105251	-0.4824024811542073	[400]	[229,85,NaN]	-3	hSpCas9	negative selection	10062803
4282943	4282966	19	+	27869803	HPAFII	viability after 31 days	TGGAGCCCTACGATGCCCAATGG	SHD	ENSG00000105251	0.41169382400287	[167]	[145,102,NaN]	3	hSpCas9	negative selection	10062819
4283183	4283206	19	+	27869803	HPAFII	viability after 31 days	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.08986787078840294	[228]	[25,223,NaN]	0	hSpCas9	negative selection	10062821
4284787	4284810	19	+	27869803	HPAFII	viability after 31 days	TTGACAGTCCAGAGTGGGAGAGG	SHD	ENSG00000105251	-0.19253475741420423	[528]	[377,130,NaN]	-1	hSpCas9	negative selection	10062827
4288350	4288373	19	-	27869803	HPAFII	viability after 31 days	GAGTTCTCACCTGAGAGACAAGG	SHD	ENSG00000105251	-1.1149586697799334	[180]	[66,24,NaN]	-6	hSpCas9	negative selection	10062828
4290626	4290649	19	-	27869803	HPAFII	viability after 31 days	GGCCGAGGGTCACTGTCAGGGGG	SHD	ENSG00000105251	0.21532518925054578	[114]	[50,100,NaN]	1	hSpCas9	negative selection	10062832
4280125	4280148	19	-	28162770	P31FUJ	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.3623082516828604	[424]	[641]	4	hSpCas9	negative selection	10233864
4280053	4280076	19	+	28162770	P31FUJ	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	0.55939291047222	[81]	[141]	6	hSpCas9	negative selection	10233865
4280285	4280308	19	+	28162770	P31FUJ	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-1.3323378779652935	[59]	[27]	-7	hSpCas9	negative selection	10233866
4282896	4282919	19	-	28162770	P31FUJ	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.07788162758703449	[246]	[274]	-1	hSpCas9	negative selection	10233867
4284806	4284829	19	+	28162770	P31FUJ	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	-0.6560136351389226	[235]	[175]	-5	hSpCas9	negative selection	10233868
4280272	4280295	19	+	28162770	P31FUJ	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	-0.25462856686755686	[332]	[327]	-2	hSpCas9	negative selection	10233869
4282877	4282900	19	-	28162770	P31FUJ	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	0.8134914478595564	[91]	[189]	8	hSpCas9	negative selection	10233870
4283183	4283206	19	+	28162770	P31FUJ	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.22228001375986772	[150]	[206]	2	hSpCas9	negative selection	10233871
4283228	4283251	19	-	28162770	P31FUJ	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	-0.13969280002289697	[89]	[95]	-1	hSpCas9	negative selection	10233872
4284861	4284884	19	-	28162770	P31FUJ	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	0.2716039422583808	[355]	[504]	3	hSpCas9	negative selection	10233873
4280125	4280148	19	-	28162770	TF1	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	NaN	[NaN]	[252]	1	hSpCas9	negative selection	10403230
4280053	4280076	19	+	28162770	TF1	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	NaN	[NaN]	[170]	1	hSpCas9	negative selection	10403231
4280285	4280308	19	+	28162770	TF1	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10403232
4282896	4282919	19	-	28162770	TF1	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10403233
4284806	4284829	19	+	28162770	TF1	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10403234
4280272	4280295	19	+	28162770	TF1	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	NaN	[NaN]	[291]	1	hSpCas9	negative selection	10403235
4282877	4282900	19	-	28162770	TF1	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10403236
4283183	4283206	19	+	28162770	TF1	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	NaN	[NaN]	[126]	1	hSpCas9	negative selection	10403237
4283228	4283251	19	-	28162770	TF1	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	NaN	[NaN]	[139]	1	hSpCas9	negative selection	10403238
4284861	4284884	19	-	28162770	TF1	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	NaN	[NaN]	[419]	1	hSpCas9	negative selection	10403239
4280125	4280148	19	-	28162770	SKM1	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.6075841098259936	[110]	[298]	6	hSpCas9	negative selection	10572596
4280053	4280076	19	+	28162770	SKM1	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	-0.03773038907744275	[17]	[30]	0	hSpCas9	negative selection	10572597
4280285	4280308	19	+	28162770	SKM1	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-1.4069641987431618	[17]	[11]	-7	hSpCas9	negative selection	10572598
4282896	4282919	19	-	28162770	SKM1	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-1.9758070341010407	[88]	[39]	-8	hSpCas9	negative selection	10572599
4284806	4284829	19	+	28162770	SKM1	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	0.016247231981382115	[65]	[117]	0	hSpCas9	negative selection	10572600
4280272	4280295	19	+	28162770	SKM1	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	-0.5888025217289747	[113]	[133]	-5	hSpCas9	negative selection	10572601
4282877	4282900	19	-	28162770	SKM1	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	0.025995208532944458	[24]	[44]	0	hSpCas9	negative selection	10572602
4283183	4283206	19	+	28162770	SKM1	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.660391069058603	[33]	[94]	6	hSpCas9	negative selection	10572603
4283228	4283251	19	-	28162770	SKM1	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	-1.5138794026596734	[20]	[12]	-7	hSpCas9	negative selection	10572604
4284861	4284884	19	-	28162770	SKM1	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	-0.06213570174572036	[74]	[126]	0	hSpCas9	negative selection	10572605
4280125	4280148	19	-	28162770	SKM1	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.6075841098259936	[110]	[298]	6	hSpCas9	negative selection	10741962
4280053	4280076	19	+	28162770	SKM1	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	-0.03773038907744275	[17]	[30]	0	hSpCas9	negative selection	10741963
4280285	4280308	19	+	28162770	SKM1	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-1.4069641987431618	[17]	[11]	-7	hSpCas9	negative selection	10741964
4282896	4282919	19	-	28162770	SKM1	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-1.9758070341010407	[88]	[39]	-8	hSpCas9	negative selection	10741965
4284806	4284829	19	+	28162770	SKM1	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	0.016247231981382115	[65]	[117]	0	hSpCas9	negative selection	10741966
4280272	4280295	19	+	28162770	SKM1	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	-0.5888025217289747	[113]	[133]	-5	hSpCas9	negative selection	10741967
4282877	4282900	19	-	28162770	SKM1	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	0.025995208532944458	[24]	[44]	0	hSpCas9	negative selection	10741968
4283183	4283206	19	+	28162770	SKM1	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.660391069058603	[33]	[94]	6	hSpCas9	negative selection	10741969
4283228	4283251	19	-	28162770	SKM1	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	-1.5138794026596734	[20]	[12]	-7	hSpCas9	negative selection	10741970
4284861	4284884	19	-	28162770	SKM1	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	-0.06213570174572036	[74]	[126]	0	hSpCas9	negative selection	10741971
4280125	4280148	19	-	28162770	PL21	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.3287817659284249	[385]	[210]	3	hSpCas9	negative selection	10911328
4280053	4280076	19	+	28162770	PL21	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	-1.455212214123234	[62]	[9]	-7	hSpCas9	negative selection	10911329
4280285	4280308	19	+	28162770	PL21	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	1.504994196017741	[50]	[62]	9	hSpCas9	negative selection	10911330
4282896	4282919	19	-	28162770	PL21	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.020411460022960237	[260]	[111]	0	hSpCas9	negative selection	10911331
4284806	4284829	19	+	28162770	PL21	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	0.02326185240524091	[207]	[91]	0	hSpCas9	negative selection	10911332
4280272	4280295	19	+	28162770	PL21	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	-0.6766489493297791	[414]	[112]	-5	hSpCas9	negative selection	10911333
4282877	4282900	19	-	28162770	PL21	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	0.5480629179096271	[76]	[48]	5	hSpCas9	negative selection	10911334
4283183	4283206	19	+	28162770	PL21	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-1.1002553188484008	[132]	[26]	-6	hSpCas9	negative selection	10911335
4283228	4283251	19	-	28162770	PL21	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	1.769505260159458	[61]	[91]	9	hSpCas9	negative selection	10911336
4284861	4284884	19	-	28162770	PL21	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	0.06143334365772807	[239]	[108]	0	hSpCas9	negative selection	10911337
4280125	4280148	19	-	28162770	P31FUJ	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.3623082516828604	[424]	[641]	4	hSpCas9	negative selection	11080694
4280053	4280076	19	+	28162770	P31FUJ	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	0.55939291047222	[81]	[141]	6	hSpCas9	negative selection	11080695
4280285	4280308	19	+	28162770	P31FUJ	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-1.3323378779652935	[59]	[27]	-7	hSpCas9	negative selection	11080696
4282896	4282919	19	-	28162770	P31FUJ	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.07788162758703449	[246]	[274]	-1	hSpCas9	negative selection	11080697
4284806	4284829	19	+	28162770	P31FUJ	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	-0.6560136351389226	[235]	[175]	-5	hSpCas9	negative selection	11080698
4280272	4280295	19	+	28162770	P31FUJ	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	-0.25462856686755686	[332]	[327]	-2	hSpCas9	negative selection	11080699
4282877	4282900	19	-	28162770	P31FUJ	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	0.8134914478595564	[91]	[189]	8	hSpCas9	negative selection	11080700
4283183	4283206	19	+	28162770	P31FUJ	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.22228001375986772	[150]	[206]	2	hSpCas9	negative selection	11080701
4283228	4283251	19	-	28162770	P31FUJ	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	-0.13969280002289697	[89]	[95]	-1	hSpCas9	negative selection	11080702
4284861	4284884	19	-	28162770	P31FUJ	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	0.2716039422583808	[355]	[504]	3	hSpCas9	negative selection	11080703
4280125	4280148	19	-	28162770	OCIAML5	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	-0.16722370777392337	[185]	[298]	-1	hSpCas9	negative selection	11250060
4280053	4280076	19	+	28162770	OCIAML5	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	-0.12858420606141285	[42]	[70]	-1	hSpCas9	negative selection	11250061
4280285	4280308	19	+	28162770	OCIAML5	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-1.6069540730274654	[26]	[15]	-7	hSpCas9	negative selection	11250062
4282896	4282919	19	-	28162770	OCIAML5	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.6346489649428414	[165]	[192]	-4	hSpCas9	negative selection	11250063
4284806	4284829	19	+	28162770	OCIAML5	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	0.4299687968998528	[87]	[213]	3	hSpCas9	negative selection	11250064
4280272	4280295	19	+	28162770	OCIAML5	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	-1.075366633023643	[264]	[226]	-6	hSpCas9	negative selection	11250065
4282877	4282900	19	-	28162770	OCIAML5	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	-0.2564568259433322	[44]	[67]	-2	hSpCas9	negative selection	11250066
4283183	4283206	19	+	28162770	OCIAML5	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.7165014916064905	[58]	[174]	6	hSpCas9	negative selection	11250067
4283228	4283251	19	-	28162770	OCIAML5	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	-1.120555406789899	[52]	[43]	-6	hSpCas9	negative selection	11250068
4284861	4284884	19	-	28162770	OCIAML5	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	-0.5640098985557706	[180]	[220]	-4	hSpCas9	negative selection	11250069
4280125	4280148	19	-	28162770	EOL1	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	-0.05113035668673138	[646]	[328]	0	hSpCas9	negative selection	11419426
4280053	4280076	19	+	28162770	EOL1	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	0.39661621588575713	[61]	[42]	3	hSpCas9	negative selection	11419427
4280285	4280308	19	+	28162770	EOL1	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-0.3555601476222008	[118]	[48]	-3	hSpCas9	negative selection	11419428
4282896	4282919	19	-	28162770	EOL1	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.183874688315451	[441]	[204]	-1	hSpCas9	negative selection	11419429
4284806	4284829	19	+	28162770	EOL1	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	-0.2353235652078547	[285]	[127]	-2	hSpCas9	negative selection	11419430
4280272	4280295	19	+	28162770	EOL1	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	0.28472333581486	[736]	[472]	2	hSpCas9	negative selection	11419431
4282877	4282900	19	-	28162770	EOL1	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	1.661513365736741	[47]	[79]	9	hSpCas9	negative selection	11419432
4283183	4283206	19	+	28162770	EOL1	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.3432055865280754	[198]	[132]	3	hSpCas9	negative selection	11419433
4283228	4283251	19	-	28162770	EOL1	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	0.6407548055699432	[55]	[45]	6	hSpCas9	negative selection	11419434
4284861	4284884	19	-	28162770	EOL1	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	0.5365304862253997	[334]	[255]	5	hSpCas9	negative selection	11419435
4280125	4280148	19	-	28162770	MOLM13	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.8963473965857444	[534]	[719]	6	hSpCas9	negative selection	11588792
4280053	4280076	19	+	28162770	MOLM13	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	-2.1468204625706293	[97]	[15]	-7	hSpCas9	negative selection	11588793
4280285	4280308	19	+	28162770	MOLM13	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	1.0251068917828308	[69]	[102]	7	hSpCas9	negative selection	11588794
4282896	4282919	19	-	28162770	MOLM13	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	0.4543428497066311	[320]	[317]	3	hSpCas9	negative selection	11588795
4284806	4284829	19	+	28162770	MOLM13	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	-0.25047899374429733	[333]	[202]	-1	hSpCas9	negative selection	11588796
4280272	4280295	19	+	28162770	MOLM13	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	-0.17634892849218364	[471]	[301]	-1	hSpCas9	negative selection	11588797
4282877	4282900	19	-	28162770	MOLM13	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	-0.1525219551808672	[102]	[66]	-1	hSpCas9	negative selection	11588798
4283183	4283206	19	+	28162770	MOLM13	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.4678893815445787	[215]	[215]	3	hSpCas9	negative selection	11588799
4283228	4283251	19	-	28162770	MOLM13	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	-1.4118163847377092	[91]	[24]	-6	hSpCas9	negative selection	11588800
4284861	4284884	19	-	28162770	MOLM13	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	-0.30789546151215547	[338]	[197]	-2	hSpCas9	negative selection	11588801
4280125	4280148	19	-	28162770	HEL	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	1.1442309293961226	[420]	[595]	8	hSpCas9	negative selection	11758158
4280053	4280076	19	+	28162770	HEL	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	1.5121547221902127	[51]	[94]	9	hSpCas9	negative selection	11758159
4280285	4280308	19	+	28162770	HEL	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-0.08240132676905954	[80]	[48]	0	hSpCas9	negative selection	11758160
4282896	4282919	19	-	28162770	HEL	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	0.3546134452037325	[347]	[284]	3	hSpCas9	negative selection	11758161
4284806	4284829	19	+	28162770	HEL	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	-0.5506451422659444	[278]	[121]	-4	hSpCas9	negative selection	11758162
4280272	4280295	19	+	28162770	HEL	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	-0.015752704142764418	[482]	[305]	0	hSpCas9	negative selection	11758163
4282877	4282900	19	-	28162770	HEL	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	-0.6509923710563532	[75]	[30]	-4	hSpCas9	negative selection	11758164
4283183	4283206	19	+	28162770	HEL	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.5033394274875878	[134]	[60]	-3	hSpCas9	negative selection	11758165
4283228	4283251	19	-	28162770	HEL	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	0.14631300588085794	[78]	[55]	1	hSpCas9	negative selection	11758166
4284861	4284884	19	-	28162770	HEL	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	0.7023276282901569	[331]	[345]	6	hSpCas9	negative selection	11758167
4280125	4280148	19	-	28162770	MV411	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.7800278747219538	[373]	[540]	7	hSpCas9	negative selection	11927524
4280053	4280076	19	+	28162770	MV411	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	0.019168563109658088	[40]	[34]	0	hSpCas9	negative selection	11927525
4280285	4280308	19	+	28162770	MV411	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-1.283077165916004	[51]	[17]	-7	hSpCas9	negative selection	11927526
4282896	4282919	19	-	28162770	MV411	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	0.0775125493404627	[251]	[223]	0	hSpCas9	negative selection	11927527
4284806	4284829	19	+	28162770	MV411	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	0.13798640836677795	[218]	[202]	1	hSpCas9	negative selection	11927528
4280272	4280295	19	+	28162770	MV411	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	0.30006448143398523	[322]	[334]	2	hSpCas9	negative selection	11927529
4282877	4282900	19	-	28162770	MV411	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	-0.0019219181539420482	[62]	[52]	0	hSpCas9	negative selection	11927530
4283183	4283206	19	+	28162770	MV411	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.6308838926289725	[124]	[67]	-4	hSpCas9	negative selection	11927531
4283228	4283251	19	-	28162770	MV411	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	1.0326987019897627	[46]	[80]	8	hSpCas9	negative selection	11927532
4284861	4284884	19	-	28162770	MV411	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	0.03289299126901235	[274]	[236]	0	hSpCas9	negative selection	11927533
4280125	4280148	19	-	28162770	MONOMAC1	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.04596585395218056	[277]	[328]	0	hSpCas9	negative selection	12096890
4280053	4280076	19	+	28162770	MONOMAC1	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	1.1764215484678906	[43]	[113]	8	hSpCas9	negative selection	12096891
4280285	4280308	19	+	28162770	MONOMAC1	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-0.8159466797040476	[42]	[27]	-6	hSpCas9	negative selection	12096892
4282896	4282919	19	-	28162770	MONOMAC1	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	0.23817853415692036	[141]	[191]	2	hSpCas9	negative selection	12096893
4284806	4284829	19	+	28162770	MONOMAC1	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	-0.01721580947474144	[112]	[127]	0	hSpCas9	negative selection	12096894
4280272	4280295	19	+	28162770	MONOMAC1	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	-0.08791512467944096	[279]	[301]	-1	hSpCas9	negative selection	12096895
4282877	4282900	19	-	28162770	MONOMAC1	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	-1.7609377322528803	[67]	[22]	-8	hSpCas9	negative selection	12096896
4283183	4283206	19	+	28162770	MONOMAC1	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	-0.14258906303717722	[77]	[80]	-1	hSpCas9	negative selection	12096897
4283228	4283251	19	-	28162770	MONOMAC1	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	0.47038781385357553	[33]	[53]	4	hSpCas9	negative selection	12096898
4284861	4284884	19	-	28162770	MONOMAC1	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	1.0579602397088217	[149]	[357]	8	hSpCas9	negative selection	12096899
4280125	4280148	19	-	28162770	OCIAML2	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.7680079262841655	[81]	[773]	7	hSpCas9	negative selection	12266256
4280053	4280076	19	+	28162770	OCIAML2	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	0.5882638638114076	[14]	[124]	6	hSpCas9	negative selection	12266257
4280285	4280308	19	+	28162770	OCIAML2	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-0.849141448495891	[12]	[39]	-5	hSpCas9	negative selection	12266258
4282896	4282919	19	-	28162770	OCIAML2	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.2255173274056299	[53]	[255]	-2	hSpCas9	negative selection	12266259
4284806	4284829	19	+	28162770	OCIAML2	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	-0.3301486016923308	[43]	[193]	-3	hSpCas9	negative selection	12266260
4280272	4280295	19	+	28162770	OCIAML2	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	0.09263760437967583	[66]	[395]	0	hSpCas9	negative selection	12266261
4282877	4282900	19	-	28162770	OCIAML2	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	-1.055592325963317	[14]	[39]	-6	hSpCas9	negative selection	12266262
4283183	4283206	19	+	28162770	OCIAML2	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	0.316961841994013	[20]	[144]	3	hSpCas9	negative selection	12266263
4283228	4283251	19	-	28162770	OCIAML2	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	-1.523097245136297	[13]	[26]	-7	hSpCas9	negative selection	12266264
4284861	4284884	19	-	28162770	OCIAML2	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	-0.1189543869607469	[47]	[244]	-1	hSpCas9	negative selection	12266265
4280125	4280148	19	-	28162770	OCIAML3	viability	GCTCTCGGTGTAGTCCGGGGTGG	SHD	ENSG00000105251	0.22938729299770855	[114]	[406]	2	hSpCas9	negative selection	12435622
4280053	4280076	19	+	28162770	OCIAML3	viability	CAGGCGCCCAAATGGCCAAGTGG	SHD	ENSG00000105251	-0.14334623131459812	[14]	[40]	-1	hSpCas9	negative selection	12435623
4280285	4280308	19	+	28162770	OCIAML3	viability	CAAGCACCGGCTCATCAAGGTGG	SHD	ENSG00000105251	-0.27207954543680124	[9]	[24]	-2	hSpCas9	negative selection	12435624
4282896	4282919	19	-	28162770	OCIAML3	viability	GATGAGGCTGAGCATCAAAGGGG	SHD	ENSG00000105251	-0.29855175679799184	[65]	[161]	-2	hSpCas9	negative selection	12435625
4284806	4284829	19	+	28162770	OCIAML3	viability	GAGGACTCCAGGCTCAGCCAAGG	SHD	ENSG00000105251	0.08229517193541884	[50]	[162]	0	hSpCas9	negative selection	12435626
4280272	4280295	19	+	28162770	OCIAML3	viability	AGTATGGTTCTCCCAAGCACCGG	SHD	ENSG00000105251	0.01127484477658891	[93]	[285]	0	hSpCas9	negative selection	12435627
4282877	4282900	19	-	28162770	OCIAML3	viability	GGGGTCTAAATACTCAGTGTCGG	SHD	ENSG00000105251	-0.009045139603006902	[16]	[50]	0	hSpCas9	negative selection	12435628
4283183	4283206	19	+	28162770	OCIAML3	viability	CAGATGAGTATGATCAGCCCTGG	SHD	ENSG00000105251	1.0542807957658222	[25]	[162]	8	hSpCas9	negative selection	12435629
4283228	4283251	19	-	28162770	OCIAML3	viability	AGAAGCACCTGCAAACGCCCTGG	SHD	ENSG00000105251	1.3535249397817013	[13]	[107]	9	hSpCas9	negative selection	12435630
4284861	4284884	19	-	28162770	OCIAML3	viability	GCTGGGTCCACACGCTCCGCAGG	SHD	ENSG00000105251	0.053690615744955816	[74]	[234]	0	hSpCas9	negative selection	12435631