Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6469
• Symbol:SHH
• Description:sonic hedgehog signaling molecule

DataSource: http://genomecrispr.dkfz.de/#!/results/SHH

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
155811840	155811863	7	-	26472758	Jiyoye	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	-0.32979021266033276	[194]	[116]	-2	hSpCas9	negative selection	146462
155806449	155806472	7	-	26472758	Jiyoye	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	-0.23728813096394474	[296]	[189]	-2	hSpCas9	negative selection	146463
155806430	155806453	7	-	26472758	Jiyoye	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.9750643688680882	[169]	[251]	6	hSpCas9	negative selection	146464
155806419	155806442	7	-	26472758	Jiyoye	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.43162842523041245	[116]	[118]	3	hSpCas9	negative selection	146465
155806390	155806413	7	+	26472758	Jiyoye	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	1.1492388433117584	[112]	[188]	7	hSpCas9	negative selection	146466
155806293	155806316	7	+	26472758	Jiyoye	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.8708867275204069	[152]	[210]	6	hSpCas9	negative selection	146467
155806488	155806511	7	-	26472758	Jiyoye	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-0.3057947315913543	[158]	[96]	-2	hSpCas9	negative selection	146468
155806374	155806397	7	+	26472758	Jiyoye	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	6.536458398450839	[0]	[69]	9	hSpCas9	negative selection	146469
155812068	155812091	7	+	26472758	Jiyoye	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.8277510643261471	[64]	[86]	6	hSpCas9	negative selection	146470
155811957	155811980	7	+	26472758	Jiyoye	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	-0.3025687439253084	[349]	[213]	-2	hSpCas9	negative selection	146471
155811840	155811863	7	-	26472758	KBM7	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	0.38750365596502073	[539,221]	[291,165]	4	hSpCas9	negative selection	337580
155806449	155806472	7	-	26472758	KBM7	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	0.5727671799290416	[958,753]	[479,696]	6	hSpCas9	negative selection	337581
155806430	155806453	7	-	26472758	KBM7	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.649593314832775	[707,587]	[451,496]	7	hSpCas9	negative selection	337582
155806419	155806442	7	-	26472758	KBM7	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.25587036378032585	[305,276]	[217,114]	2	hSpCas9	negative selection	337583
155806390	155806413	7	+	26472758	KBM7	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	2.4186019921136657	[509,589]	[2123,751]	9	hSpCas9	negative selection	337584
155806293	155806316	7	+	26472758	KBM7	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.6851170578500094	[745,625]	[478,549]	7	hSpCas9	negative selection	337585
155806488	155806511	7	-	26472758	KBM7	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-0.33432384493762685	[612,633]	[317,158]	-3	hSpCas9	negative selection	337586
155806374	155806397	7	+	26472758	KBM7	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	0.1904631990773902	[542,289]	[205,227]	2	hSpCas9	negative selection	337587
155812068	155812091	7	+	26472758	KBM7	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.3109389251439015	[413,321]	[213,211]	3	hSpCas9	negative selection	337588
155811957	155811980	7	+	26472758	KBM7	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	0.5585690153566241	[972,615]	[469,602]	6	hSpCas9	negative selection	337589
155811840	155811863	7	-	26472758	Raji	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	0.34908943176688134	[158]	[46]	3	hSpCas9	negative selection	528698
155806449	155806472	7	-	26472758	Raji	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	0.020699476890289614	[462]	[108]	0	hSpCas9	negative selection	528699
155806430	155806453	7	-	26472758	Raji	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	1.2939795686431905	[238]	[135]	9	hSpCas9	negative selection	528700
155806419	155806442	7	-	26472758	Raji	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.4884672814902927	[132]	[21]	-4	hSpCas9	negative selection	528701
155806390	155806413	7	+	26472758	Raji	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	-0.09323826329162938	[284]	[61]	-1	hSpCas9	negative selection	528702
155806293	155806316	7	+	26472758	Raji	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.36441920058595023	[240]	[71]	3	hSpCas9	negative selection	528703
155806488	155806511	7	-	26472758	Raji	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-1.297872943112659	[391]	[36]	-7	hSpCas9	negative selection	528704
155806374	155806397	7	+	26472758	Raji	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	0.3188876405673112	[151]	[43]	3	hSpCas9	negative selection	528705
155812068	155812091	7	+	26472758	Raji	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.06298941601514596	[230]	[55]	0	hSpCas9	negative selection	528706
155811957	155811980	7	+	26472758	Raji	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	0.6346305382384684	[407]	[146]	6	hSpCas9	negative selection	528707
155811840	155811863	7	-	26472758	K562	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	-0.5910455003216626	[297]	[166]	-4	hSpCas9	negative selection	719816
155806449	155806472	7	-	26472758	K562	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	-0.6180777485836182	[679]	[373]	-4	hSpCas9	negative selection	719817
155806430	155806453	7	-	26472758	K562	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.050331675550144506	[571]	[499]	0	hSpCas9	negative selection	719818
155806419	155806442	7	-	26472758	K562	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.787430138372893	[228]	[111]	-5	hSpCas9	negative selection	719819
155806390	155806413	7	+	26472758	K562	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	0.2632777549177629	[455]	[461]	2	hSpCas9	negative selection	719820
155806293	155806316	7	+	26472758	K562	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.889588157424827	[570]	[892]	7	hSpCas9	negative selection	719821
155806488	155806511	7	-	26472758	K562	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-1.9636894676637533	[401]	[86]	-7	hSpCas9	negative selection	719822
155806374	155806397	7	+	26472758	K562	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	1.0992208121265112	[140]	[254]	8	hSpCas9	negative selection	719823
155812068	155812091	7	+	26472758	K562	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.7639868104165974	[345]	[495]	6	hSpCas9	negative selection	719824
155811957	155811980	7	+	26472758	K562	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	0.49660575126324824	[800]	[953]	4	hSpCas9	negative selection	719825
155800616	155800639	7	-	26627737	DLD1	viability	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	1.1539255095481593	[128]	[136,51,79]	9	hSpCas9	negative selection	835740
155802907	155802930	7	+	26627737	DLD1	viability	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	0.13637895172395365	[584]	[286,209,118]	1	hSpCas9	negative selection	835741
155806295	155806318	7	-	26627737	DLD1	viability	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	1.01079462329495	[551]	[319,391,334]	8	hSpCas9	negative selection	835742
155806491	155806514	7	+	26627737	DLD1	viability	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	-1.1455204784954798	[474]	[103,82,21]	-7	hSpCas9	negative selection	835743
155806699	155806722	7	+	26627737	DLD1	viability	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	-0.28111591059549645	[846]	[152,211,278]	-3	hSpCas9	negative selection	835744
155812068	155812091	7	+	26627737	DLD1	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.017448287261488837	[768]	[371,112,223]	0	hSpCas9	negative selection	835745
155800616	155800639	7	-	26627737	GBM cells	viability after 5 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-0.22370541177827008	[134]	[53,69]	-3	hSpCas9	negative selection	918055
155802907	155802930	7	+	26627737	GBM cells	viability after 5 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.12780346349009375	[217]	[106,106]	-2	hSpCas9	negative selection	918056
155806295	155806318	7	-	26627737	GBM cells	viability after 5 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.07899549136416922	[345]	[161,229]	1	hSpCas9	negative selection	918057
155806491	155806514	7	+	26627737	GBM cells	viability after 5 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.10836724051463531	[127]	[53,93]	1	hSpCas9	negative selection	918058
155806699	155806722	7	+	26627737	GBM cells	viability after 5 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	0.02222351705286635	[324]	[182,170]	0	hSpCas9	negative selection	918059
155812068	155812091	7	+	26627737	GBM cells	viability after 5 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.003701320453613821	[357]	[217,164]	0	hSpCas9	negative selection	918060
155800616	155800639	7	-	26627737	GBM cells	viability after 13 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-0.19769907726883018	[134]	[75,53]	-2	hSpCas9	negative selection	1000370
155802907	155802930	7	+	26627737	GBM cells	viability after 13 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	0.20644277688597504	[217]	[200,83]	2	hSpCas9	negative selection	1000371
155806295	155806318	7	-	26627737	GBM cells	viability after 13 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.03023205988491179	[345]	[206,164]	0	hSpCas9	negative selection	1000372
155806491	155806514	7	+	26627737	GBM cells	viability after 13 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	-0.3665497319633325	[127]	[65,43]	-4	hSpCas9	negative selection	1000373
155806699	155806722	7	+	26627737	GBM cells	viability after 13 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	0.2645262586025717	[324]	[202,218]	3	hSpCas9	negative selection	1000374
155812068	155812091	7	+	26627737	GBM cells	viability after 13 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.0222763917786174	[357]	[247,155]	0	hSpCas9	negative selection	1000375
155800616	155800639	7	-	26627737	GBM cells	viability after 21 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	0.9919241297488658	[134]	[148,142]	8	hSpCas9	negative selection	1082685
155802907	155802930	7	+	26627737	GBM cells	viability after 21 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.17982511387504357	[217]	[114,94]	-2	hSpCas9	negative selection	1082686
155806295	155806318	7	-	26627737	GBM cells	viability after 21 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.6717518786592251	[345]	[117,117]	-5	hSpCas9	negative selection	1082687
155806491	155806514	7	+	26627737	GBM cells	viability after 21 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	-0.55871216840073	[127]	[53,40]	-5	hSpCas9	negative selection	1082688
155806699	155806722	7	+	26627737	GBM cells	viability after 21 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	-0.24027539746514912	[324]	[149,148]	-2	hSpCas9	negative selection	1082689
155812068	155812091	7	+	26627737	GBM cells	viability after 21 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.24162876470646832	[357]	[230,228]	2	hSpCas9	negative selection	1082690
155800616	155800639	7	-	26627737	RPE1	viability after 9 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-0.37034524166514604	[439]	[137,65]	-3	hSpCas9	negative selection	1165000
155802907	155802930	7	+	26627737	RPE1	viability after 9 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	0.5321016648709693	[533]	[177,323]	3	hSpCas9	negative selection	1165001
155806295	155806318	7	-	26627737	RPE1	viability after 9 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.16806633729848436	[1007]	[292,433]	1	hSpCas9	negative selection	1165002
155806491	155806514	7	+	26627737	RPE1	viability after 9 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	3.6363132163110334	[19]	[7,167]	9	hSpCas9	negative selection	1165003
155806699	155806722	7	+	26627737	RPE1	viability after 9 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	0.5608382376524951	[1051]	[494,473]	4	hSpCas9	negative selection	1165004
155812068	155812091	7	+	26627737	RPE1	viability after 9 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.43366112907598753	[1121]	[349,634]	3	hSpCas9	negative selection	1165005
155800616	155800639	7	-	26627737	RPE1	viability after 12 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-0.9859345417293799	[439]	[65,52]	-6	hSpCas9	negative selection	1247315
155802907	155802930	7	+	26627737	RPE1	viability after 12 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.07318691590717874	[533]	[131,140]	0	hSpCas9	negative selection	1247316
155806295	155806318	7	-	26627737	RPE1	viability after 12 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.6655857186896201	[1007]	[431,426]	4	hSpCas9	negative selection	1247317
155806491	155806514	7	+	26627737	RPE1	viability after 12 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	4.01143008246498	[19]	[57,116]	9	hSpCas9	negative selection	1247318
155806699	155806722	7	+	26627737	RPE1	viability after 12 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	0.5041367939431304	[1051]	[463,333]	3	hSpCas9	negative selection	1247319
155812068	155812091	7	+	26627737	RPE1	viability after 12 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.7281413751338635	[1121]	[493,504]	5	hSpCas9	negative selection	1247320
155800616	155800639	7	-	26627737	RPE1	viability after 15 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-0.5569556359441774	[439]	[134,35]	-4	hSpCas9	negative selection	1329630
155802907	155802930	7	+	26627737	RPE1	viability after 15 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	0.20686366992923372	[533]	[182,165]	1	hSpCas9	negative selection	1329631
155806295	155806318	7	-	26627737	RPE1	viability after 15 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.3019798270668736	[1007]	[405,298]	2	hSpCas9	negative selection	1329632
155806491	155806514	7	+	26627737	RPE1	viability after 15 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	4.730748657237361	[19]	[165,134]	9	hSpCas9	negative selection	1329633
155806699	155806722	7	+	26627737	RPE1	viability after 15 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	-0.03477576201587912	[1051]	[402,181]	0	hSpCas9	negative selection	1329634
155812068	155812091	7	+	26627737	RPE1	viability after 15 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.6211040602480131	[1121]	[450,523]	4	hSpCas9	negative selection	1329635
155800616	155800639	7	-	26627737	RPE1	viability after 18 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-0.8025202697112161	[439]	[84,49]	-5	hSpCas9	negative selection	1411945
155802907	155802930	7	+	26627737	RPE1	viability after 18 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	0.33631607944031533	[533]	[223,136]	2	hSpCas9	negative selection	1411946
155806295	155806318	7	-	26627737	RPE1	viability after 18 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.13148802236125512	[1007]	[180,422]	0	hSpCas9	negative selection	1411947
155806491	155806514	7	+	26627737	RPE1	viability after 18 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	4.507528246808761	[19]	[115,129]	9	hSpCas9	negative selection	1411948
155806699	155806722	7	+	26627737	RPE1	viability after 18 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	0.43580079765323143	[1051]	[442,320]	2	hSpCas9	negative selection	1411949
155812068	155812091	7	+	26627737	RPE1	viability after 18 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.7684288889173119	[1121]	[625,397]	5	hSpCas9	negative selection	1411950
155800616	155800639	7	-	26627737	HeLa	viability after 8 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-0.6342472807945853	[358]	[105,79,115]	-6	hSpCas9	negative selection	1494260
155802907	155802930	7	+	26627737	HeLa	viability after 8 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.983439045067367	[587]	[172,112,112]	-7	hSpCas9	negative selection	1494261
155806295	155806318	7	-	26627737	HeLa	viability after 8 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.6476918701470052	[463]	[245,393,294]	5	hSpCas9	negative selection	1494262
155806491	155806514	7	+	26627737	HeLa	viability after 8 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.5857237219229563	[219]	[137,121,167]	5	hSpCas9	negative selection	1494263
155806699	155806722	7	+	26627737	HeLa	viability after 8 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	2.0651092193749836	[193]	[423,233,412]	9	hSpCas9	negative selection	1494264
155812068	155812091	7	+	26627737	HeLa	viability after 8 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.719186571653949	[1033]	[286,322,216]	-6	hSpCas9	negative selection	1494265
155800616	155800639	7	-	26627737	HeLa	viability after 12 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	0.25133040931384626	[358]	[185,129,218]	2	hSpCas9	negative selection	1576575
155802907	155802930	7	+	26627737	HeLa	viability after 12 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.10320112865104564	[587]	[247,247,180]	-1	hSpCas9	negative selection	1576576
155806295	155806318	7	-	26627737	HeLa	viability after 12 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.39298511976643247	[463]	[187,303,255]	3	hSpCas9	negative selection	1576577
155806491	155806514	7	+	26627737	HeLa	viability after 12 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	1.079896097519192	[219]	[94,236,236]	7	hSpCas9	negative selection	1576578
155806699	155806722	7	+	26627737	HeLa	viability after 12 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	1.9031257096230458	[193]	[447,147,323]	9	hSpCas9	negative selection	1576579
155812068	155812091	7	+	26627737	HeLa	viability after 12 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.36624138141740636	[1033]	[337,243,421]	-3	hSpCas9	negative selection	1576580
155800616	155800639	7	-	26627737	HeLa	viability after 15 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-1.0159422657301933	[358]	[44,113,56]	-7	hSpCas9	negative selection	1658890
155802907	155802930	7	+	26627737	HeLa	viability after 15 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.38943625087754474	[587]	[299,108,133]	-3	hSpCas9	negative selection	1658891
155806295	155806318	7	-	26627737	HeLa	viability after 15 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.2755591135188433	[463]	[156,178,360]	2	hSpCas9	negative selection	1658892
155806491	155806514	7	+	26627737	HeLa	viability after 15 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.7898228534483032	[219]	[164,100,201]	6	hSpCas9	negative selection	1658893
155806699	155806722	7	+	26627737	HeLa	viability after 15 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	1.8742090245538712	[193]	[451,118,295]	9	hSpCas9	negative selection	1658894
155812068	155812091	7	+	26627737	HeLa	viability after 15 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.19696355808049648	[1033]	[282,497,317]	-2	hSpCas9	negative selection	1658895
155800616	155800639	7	-	26627737	HeLa	viability after 18 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-1.021180190338513	[358]	[29,93,56]	-7	hSpCas9	negative selection	1741205
155802907	155802930	7	+	26627737	HeLa	viability after 18 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.4069703693404086	[587]	[197,88,133]	-4	hSpCas9	negative selection	1741206
155806295	155806318	7	-	26627737	HeLa	viability after 18 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.2855309267463546	[463]	[110,144,360]	2	hSpCas9	negative selection	1741207
155806491	155806514	7	+	26627737	HeLa	viability after 18 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.8106795368652769	[219]	[117,79,201]	6	hSpCas9	negative selection	1741208
155806699	155806722	7	+	26627737	HeLa	viability after 18 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	1.8538144955091718	[193]	[298,93,295]	9	hSpCas9	negative selection	1741209
155812068	155812091	7	+	26627737	HeLa	viability after 18 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.20540881821981372	[1033]	[181,416,317]	-2	hSpCas9	negative selection	1741210
155800616	155800639	7	-	26627737	HCT116	viability after 6 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-1.3754126679243681	[465]	[73,2]	-7	hSpCas9	negative selection	1823520
155802907	155802930	7	+	26627737	HCT116	viability after 6 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	0.5092409388644553	[1004]	[55,317]	3	hSpCas9	negative selection	1823521
155806295	155806318	7	-	26627737	HCT116	viability after 6 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-1.3233082772937719	[891]	[95,33]	-6	hSpCas9	negative selection	1823522
155806491	155806514	7	+	26627737	HCT116	viability after 6 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.5571232948832082	[656]	[82,189]	3	hSpCas9	negative selection	1823523
155806699	155806722	7	+	26627737	HCT116	viability after 6 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	0.8080191611361667	[1363]	[484,314]	4	hSpCas9	negative selection	1823524
155812068	155812091	7	+	26627737	HCT116	viability after 6 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.807262469622123	[576]	[315,71]	4	hSpCas9	negative selection	1823525
155800616	155800639	7	-	26627737	HCT116	viability after 8 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	0.09644063102843092	[176]	[135,40,135]	1	hSpCas9	negative selection	1905835
155802907	155802930	7	+	26627737	HCT116	viability after 8 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.8080858986251025	[518]	[206,137,145]	-7	hSpCas9	negative selection	1905836
155806295	155806318	7	-	26627737	HCT116	viability after 8 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.7580894472086264	[243]	[203,270,206]	7	hSpCas9	negative selection	1905837
155806491	155806514	7	+	26627737	HCT116	viability after 8 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.6905469184093087	[155]	[166,135,113]	6	hSpCas9	negative selection	1905838
155806699	155806722	7	+	26627737	HCT116	viability after 8 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	0.373657845524315	[409]	[244,233,396]	4	hSpCas9	negative selection	1905839
155812068	155812091	7	+	26627737	HCT116	viability after 8 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.7191342271930533	[306]	[227,283,321]	6	hSpCas9	negative selection	1905840
155800616	155800639	7	-	26627737	HCT116	viability after 9 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-0.054148191136946355	[465]	[230,31]	0	hSpCas9	negative selection	1988150
155802907	155802930	7	+	26627737	HCT116	viability after 9 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.402526011460207	[1004]	[116,270]	-3	hSpCas9	negative selection	1988151
155806295	155806318	7	-	26627737	HCT116	viability after 9 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.9162595993654559	[891]	[128,123]	-6	hSpCas9	negative selection	1988152
155806491	155806514	7	+	26627737	HCT116	viability after 9 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	-0.5626750881357486	[656]	[77,150]	-4	hSpCas9	negative selection	1988153
155806699	155806722	7	+	26627737	HCT116	viability after 9 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	-0.2269482205861718	[1363]	[294,323]	-1	hSpCas9	negative selection	1988154
155812068	155812091	7	+	26627737	HCT116	viability after 9 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	1.9165217409274173	[576]	[856,363]	9	hSpCas9	negative selection	1988155
155800616	155800639	7	-	26627737	HCT116	viability after 12 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-0.20597040559782387	[176]	[105,92,40]	-2	hSpCas9	negative selection	2070465
155802907	155802930	7	+	26627737	HCT116	viability after 12 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.576150527004292	[518]	[216,147,179]	-6	hSpCas9	negative selection	2070466
155806295	155806318	7	-	26627737	HCT116	viability after 12 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.03539771007874243	[243]	[136,111,124]	0	hSpCas9	negative selection	2070467
155806491	155806514	7	+	26627737	HCT116	viability after 12 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.7821833379043863	[155]	[135,206,81]	7	hSpCas9	negative selection	2070468
155806699	155806722	7	+	26627737	HCT116	viability after 12 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	0.7128635116731482	[409]	[289,516,261]	6	hSpCas9	negative selection	2070469
155812068	155812091	7	+	26627737	HCT116	viability after 12 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.2571554355564834	[306]	[53,171,186]	-3	hSpCas9	negative selection	2070470
155800616	155800639	7	-	26627737	HCT116	viability after 15 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	0.08807943233068405	[176]	[94,72,153]	0	hSpCas9	negative selection	2152780
155802907	155802930	7	+	26627737	HCT116	viability after 15 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.9737086645124706	[518]	[224,151,87]	-7	hSpCas9	negative selection	2152781
155806295	155806318	7	-	26627737	HCT116	viability after 15 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.55136651333614	[243]	[196,208,208]	5	hSpCas9	negative selection	2152782
155806491	155806514	7	+	26627737	HCT116	viability after 15 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.12329100701056239	[155]	[198,83,22]	1	hSpCas9	negative selection	2152783
155806699	155806722	7	+	26627737	HCT116	viability after 15 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	0.16621232925778295	[409]	[518,152,152]	1	hSpCas9	negative selection	2152784
155812068	155812091	7	+	26627737	HCT116	viability after 15 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.1589876138910396	[306]	[206,205,178]	1	hSpCas9	negative selection	2152785
155800616	155800639	7	-	26627737	HCT116	viability after 18 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	0.6222691755520038	[176]	[135,19,251]	5	hSpCas9	negative selection	2235095
155802907	155802930	7	+	26627737	HCT116	viability after 18 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.6915908751727365	[518]	[212,157,91]	-6	hSpCas9	negative selection	2235096
155806295	155806318	7	-	26627737	HCT116	viability after 18 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.43684376639257283	[243]	[155,92,237]	4	hSpCas9	negative selection	2235097
155806491	155806514	7	+	26627737	HCT116	viability after 18 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	-0.8514088826799556	[155]	[47,16,62]	-7	hSpCas9	negative selection	2235098
155806699	155806722	7	+	26627737	HCT116	viability after 18 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	0.6120789652618676	[409]	[430,180,304]	5	hSpCas9	negative selection	2235099
155812068	155812091	7	+	26627737	HCT116	viability after 18 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.33485894533096916	[306]	[131,231,194]	3	hSpCas9	negative selection	2235100
155811936	155811959	7	+	24336569	HL60	viability	CATACCTTCCGCTGGCGCCTAGG	SHH	ENSG00000164690	-0.7862970738542938	[184]	[226]	-6	hSpCas9	negative selection	2294953
155811955	155811978	7	+	24336569	HL60	viability	TAGGGTCTTCTCGGCCACATTGG	SHH	ENSG00000164690	-0.0869185307210044	[529]	[1055]	0	hSpCas9	negative selection	2294954
155811980	155812003	7	+	24336569	HL60	viability	ATAAACTGCTTGTAGGCTAAAGG	SHH	ENSG00000164690	1.4067368445562383	[166]	[936]	8	hSpCas9	negative selection	2294955
155812038	155812061	7	-	24336569	HL60	viability	ACTGGCGTGCGGACCGGGCAGGG	SHH	ENSG00000164690	0.44319788982444575	[512]	[1475]	4	hSpCas9	negative selection	2294956
155812043	155812066	7	-	24336569	HL60	viability	TCGGGACTGGCGTGCGGACCGGG	SHH	ENSG00000164690	0.5641732322736092	[938]	[2937]	5	hSpCas9	negative selection	2294957
155812049	155812072	7	-	24336569	HL60	viability	GTATGCTCGGGACTGGCGTGCGG	SHH	ENSG00000164690	0.3825655938108905	[654]	[1806]	3	hSpCas9	negative selection	2294958
155812056	155812079	7	-	24336569	HL60	viability	GCTGCTGGTATGCTCGGGACTGG	SHH	ENSG00000164690	-0.2620363462707172	[373]	[659]	-2	hSpCas9	negative selection	2294959
155812061	155812084	7	-	24336569	HL60	viability	TCCTCGCTGCTGGTATGCTCGGG	SHH	ENSG00000164690	-1.5109527562052805	[601]	[446]	-8	hSpCas9	negative selection	2294960
155812068	155812091	7	+	24336569	HL60	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.1004335424794921	[639]	[1451]	1	hSpCas9	negative selection	2294961
155812110	155812133	7	-	24336569	HL60	viability	CATGGGCGAGATGCTGCTGCTGG	SHH	ENSG00000164690	0.06055490424353149	[898]	[1983]	0	hSpCas9	negative selection	2294962
155811936	155811959	7	+	24336569	KBM7	viability	CATACCTTCCGCTGGCGCCTAGG	SHH	ENSG00000164690	0.014388657797370197	[154]	[426]	0	hSpCas9	negative selection	2362130
155811955	155811978	7	+	24336569	KBM7	viability	TAGGGTCTTCTCGGCCACATTGG	SHH	ENSG00000164690	-0.3399930583550411	[690]	[1488]	-3	hSpCas9	negative selection	2362131
155811980	155812003	7	+	24336569	KBM7	viability	ATAAACTGCTTGTAGGCTAAAGG	SHH	ENSG00000164690	-0.3352052176687286	[178]	[386]	-3	hSpCas9	negative selection	2362132
155812038	155812061	7	-	24336569	KBM7	viability	ACTGGCGTGCGGACCGGGCAGGG	SHH	ENSG00000164690	0.4386950674177124	[342]	[1267]	4	hSpCas9	negative selection	2362133
155812043	155812066	7	-	24336569	KBM7	viability	TCGGGACTGGCGTGCGGACCGGG	SHH	ENSG00000164690	0.19021481114490668	[848]	[2641]	1	hSpCas9	negative selection	2362134
155812049	155812072	7	-	24336569	KBM7	viability	GTATGCTCGGGACTGGCGTGCGG	SHH	ENSG00000164690	0.525336014622776	[577]	[2268]	5	hSpCas9	negative selection	2362135
155812056	155812079	7	-	24336569	KBM7	viability	GCTGCTGGTATGCTCGGGACTGG	SHH	ENSG00000164690	-0.17909036062298056	[351]	[847]	-1	hSpCas9	negative selection	2362136
155812061	155812084	7	-	24336569	KBM7	viability	TCCTCGCTGCTGGTATGCTCGGG	SHH	ENSG00000164690	0.5449649985320701	[290]	[1157]	5	hSpCas9	negative selection	2362137
155812068	155812091	7	+	24336569	KBM7	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.38171337154713814	[633]	[2252]	3	hSpCas9	negative selection	2362138
155812110	155812133	7	-	24336569	KBM7	viability	CATGGGCGAGATGCTGCTGCTGG	SHH	ENSG00000164690	-0.15640431035058733	[824]	[2018]	-1	hSpCas9	negative selection	2362139
155806430	155806453	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.0902066655179654	[3,3]	[2,3]	1	hSpCas9	positive selection	3020163
155811931	155811954	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	-0.3946343334030469	[3,2]	[3,0]	-5	hSpCas9	positive selection	3020164
155803625	155803648	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGAAGGACCTGAGCCCCGGGG	SHH	ENSG00000164690	0.2108794935944475	[2,1]	[1,2]	4	hSpCas9	positive selection	3020165
155811893	155811916	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGAGTTCCTTAAATCGCTCGG	SHH	ENSG00000164690	-0.13145935406781634	[4,4]	[4,2]	-2	hSpCas9	positive selection	3020166
155806430	155806453	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	-0.6358199274363839	[3,3]	[2,0]	-8	hSpCas9	positive selection	3088021
155811931	155811954	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	-0.31913823850752143	[3,3]	[2,1]	-5	hSpCas9	positive selection	3088022
155803625	155803648	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGAAGGACCTGAGCCCCGGGG	SHH	ENSG00000164690	-0.5398651904204405	[2,2]	[1,0]	-7	hSpCas9	positive selection	3088023
155811893	155811916	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGAGTTCCTTAAATCGCTCGG	SHH	ENSG00000164690	0.38927177289062226	[4,4]	[3,5]	6	hSpCas9	positive selection	3088024
155806295	155806318		-	24336571	A375	resistance to PLX after 7 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.1064543882519689	[7,8]	[9,8]	3	hSpCas9	positive selection	3144102
155803441	155803464		-	24336571	A375	resistance to PLX after 7 days	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	-0.1625739869500531	[23,21]	[20,19]	-5	hSpCas9	positive selection	3144104
155803185	155803208		+	24336571	A375	resistance to PLX after 7 days	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.35681075747609686	[13,15]	[21,15]	8	hSpCas9	positive selection	3144105
155806419	155806442		-	24336571	A375	resistance to PLX after 7 days	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.06129452000399849	[4,3]	[5,3]	2	hSpCas9	positive selection	3144106
155806295	155806318		-	24336571	A375	resistance to PLX after 14 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.48756829966841103	[7,7]	[3,4]	4	hSpCas9	positive selection	3201895
155803441	155803464		-	24336571	A375	resistance to PLX after 14 days	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.25925101773039205	[15,20]	[11,7]	2	hSpCas9	positive selection	3201897
155803185	155803208		+	24336571	A375	resistance to PLX after 14 days	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	3.479529959618699	[9,12]	[54,68]	9	hSpCas9	positive selection	3201898
155806419	155806442		-	24336571	A375	resistance to PLX after 14 days	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.00011318776969160282	[6,2]	[1,1]	0	hSpCas9	positive selection	3201899
155806295	155806318		-	24336571	A375	viability after 7 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.0704368624252325	[9]	[7,8]	-1	hSpCas9	negative selection	3259688
155803441	155803464		-	24336571	A375	viability after 7 days	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.8085023094090793	[13]	[23,21]	9	hSpCas9	negative selection	3259690
155803185	155803208		+	24336571	A375	viability after 7 days	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.12260779459577327	[13]	[13,15]	1	hSpCas9	negative selection	3259691
155806419	155806442		-	24336571	A375	viability after 7 days	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.022802946097476795	[4]	[4,3]	0	hSpCas9	negative selection	3259692
155806295	155806318		-	24336571	A375	viability after 14 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.23044912904892756	[9]	[7,7]	-3	hSpCas9	negative selection	3317481
155803441	155803464		-	24336571	A375	viability after 14 days	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.5121669173771507	[13]	[15,20]	6	hSpCas9	negative selection	3317483
155803185	155803208		+	24336571	A375	viability after 14 days	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.22012157954178385	[13]	[9,12]	-3	hSpCas9	negative selection	3317484
155806419	155806442		-	24336571	A375	viability after 14 days	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.02254505752194813	[4]	[6,2]	0	hSpCas9	negative selection	3317485
155811835	155811858	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	1.5568864933047428	[51,51]	[0,0]	6	hSpCas9	positive selection	3392336
155806530	155806553	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	0.28004628794591846	[125,125]	[0,0]	1	hSpCas9	positive selection	3392337
155806419	155806442	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	1.399345216318263	[57,57]	[0,0]	6	hSpCas9	positive selection	3392338
155806430	155806453	7	-	26780180	HT29	viability (Avana library 4 designs)	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	1.93223647495173	[]	[]	7	hSpCas9	negative selection	3458667
155811931	155811954	7	-	26780180	HT29	viability (Avana library 4 designs)	GCGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	0.859991583748099	[]	[]	3	hSpCas9	negative selection	3458668
155803625	155803648	7	-	26780180	HT29	viability (Avana library 4 designs)	GGTGAAGGACCTGAGCCCCGGGG	SHH	ENSG00000164690	1.70759357233082	[]	[]	6	hSpCas9	negative selection	3458669
155811892	155811915	7	+	26780180	HT29	viability (Avana library 4 designs)	GGTGAGTTCCTTAAATCGCTCGG	SHH	ENSG00000164690	-0.16424833351697	[]	[]	-3	hSpCas9	negative selection	3458670
155811931	155811954	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	4.32842916027331	[]	[]	7	hSpCas9	negative selection	3558220
155811892	155811915	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGAGTTCCTTAAATCGCTCGG	SHH	ENSG00000164690	3.21711286466785	[]	[]	5	hSpCas9	negative selection	3558221
155806430	155806453	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	-0.951888888835575	[]	[]	-1	hSpCas9	negative selection	3558222
155803625	155803648	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGAAGGACCTGAGCCCCGGGG	SHH	ENSG00000164690	-0.122517476499887	[]	[]	0	hSpCas9	negative selection	3558223
155803601	155803624	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCGTCCGCCGCCAGCACGCGG	SHH	ENSG00000164690	3.53292609358732	[]	[]	5	hSpCas9	negative selection	3558224
155811845	155811868	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTAAGGATGAAGAAAACACCGG	SHH	ENSG00000164690	-15.5901925788625	[]	[]	-9	hSpCas9	negative selection	3558225
155811931	155811954	7	-	26780180	A375	viability (Avana lentiGuide)	GCGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	-2.31026576268456	[]	[]	-4	hSpCas9	negative selection	3666879
155811892	155811915	7	+	26780180	A375	viability (Avana lentiGuide)	GGTGAGTTCCTTAAATCGCTCGG	SHH	ENSG00000164690	-2.41231152917191	[]	[]	-4	hSpCas9	negative selection	3666880
155806430	155806453	7	-	26780180	A375	viability (Avana lentiGuide)	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	11.2086961793223	[]	[]	7	hSpCas9	negative selection	3666881
155803625	155803648	7	-	26780180	A375	viability (Avana lentiGuide)	GGTGAAGGACCTGAGCCCCGGGG	SHH	ENSG00000164690	15.2963167227627	[]	[]	8	hSpCas9	negative selection	3666882
155803601	155803624	7	+	26780180	A375	viability (Avana lentiGuide)	GGTCGTCCGCCGCCAGCACGCGG	SHH	ENSG00000164690	-1.23459882750308	[]	[]	-2	hSpCas9	negative selection	3666883
155811845	155811868	7	-	26780180	A375	viability (Avana lentiGuide)	TTTAAGGATGAAGAAAACACCGG	SHH	ENSG00000164690	5.97682327577874	[]	[]	5	hSpCas9	negative selection	3666884
155811931	155811954	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	0.015220649676331272	[4]	[5,3]	0	hSpCas9	positive selection	3775486
155811892	155811915	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGAGTTCCTTAAATCGCTCGG	SHH	ENSG00000164690	0.09659725252736	[4]	[5,4]	2	hSpCas9	positive selection	3775487
155806430	155806453	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	-0.0634096267617526	[4]	[4,3]	-1	hSpCas9	positive selection	3775488
155803625	155803648	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGAAGGACCTGAGCCCCGGGG	SHH	ENSG00000164690	-0.30922971276178934	[3]	[4,0]	-5	hSpCas9	positive selection	3775489
155803601	155803624	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCGTCCGCCGCCAGCACGCGG	SHH	ENSG00000164690	0.2562333996972739	[4]	[5,5]	7	hSpCas9	positive selection	3775490
155811845	155811868	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTAAGGATGAAGAAAACACCGG	SHH	ENSG00000164690	-0.7694160534817244	[8]	[4,3]	-8	hSpCas9	positive selection	3775491
155811931	155811954	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	0.08325188176183529	[4]	[4,4]	1	hSpCas9	positive selection	3884093
155811892	155811915	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGAGTTCCTTAAATCGCTCGG	SHH	ENSG00000164690	-0.05851454340761152	[5]	[4,4]	-1	hSpCas9	positive selection	3884094
155806430	155806453	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	-1.1839373952136047	[4]	[0,1]	-9	hSpCas9	positive selection	3884095
155803625	155803648	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGAAGGACCTGAGCCCCGGGG	SHH	ENSG00000164690	-1.1164375751921256	[4]	[0,1]	-8	hSpCas9	positive selection	3884096
155803601	155803624	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCGTCCGCCGCCAGCACGCGG	SHH	ENSG00000164690	-0.06713537150472551	[5]	[4,3]	-1	hSpCas9	positive selection	3884097
155811845	155811868	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTAAGGATGAAGAAAACACCGG	SHH	ENSG00000164690	0.09110547006463404	[6]	[5,5]	2	hSpCas9	positive selection	3884098
155811835	155811858	7	-	26780180	A375	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.472205513780708	[]	[]	1	hSpCas9	negative selection	3994146
155803441	155803464	7	-	26780180	A375	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.816149920788198	[]	[]	3	hSpCas9	negative selection	3994147
155803185	155803208	7	+	26780180	A375	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	1.39591104459181	[]	[]	7	hSpCas9	negative selection	3994148
155812044	155812067	7	-	26780180	A375	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.772496367296402	[]	[]	3	hSpCas9	negative selection	3994149
155806419	155806442	7	-	26780180	A375	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.706262229655589	[]	[]	2	hSpCas9	negative selection	3994150
155806530	155806553	7	-	26780180	A375	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	1.38455666106339	[]	[]	7	hSpCas9	negative selection	3994151
155811835	155811858	7	-	26780180	HT29	viability (GeCKOv2 library)	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.253683708733411	[]	[]	0	hSpCas9	negative selection	4102112
155803441	155803464	7	-	26780180	HT29	viability (GeCKOv2 library)	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.861868184018621	[]	[]	3	hSpCas9	negative selection	4102113
155803185	155803208	7	+	26780180	HT29	viability (GeCKOv2 library)	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	1.13026331988738	[]	[]	5	hSpCas9	negative selection	4102114
155812044	155812067	7	-	26780180	HT29	viability (GeCKOv2 library)	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.981780694456947	[]	[]	4	hSpCas9	negative selection	4102115
155806419	155806442	7	-	26780180	HT29	viability (GeCKOv2 library)	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	1.34552664035094	[]	[]	6	hSpCas9	negative selection	4102116
155806530	155806553	7	-	26780180	HT29	viability (GeCKOv2 library)	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	1.52898646272222	[]	[]	7	hSpCas9	negative selection	4102117
155806295	155806318	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.14590077377107655	[3]	[1,2]	-3	hSpCas9	positive selection	4170035
155803441	155803464	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.12047647889264188	[3]	[2,3]	3	hSpCas9	positive selection	4170037
155803185	155803208	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.5617031227933712	[3]	[2,5]	9	hSpCas9	positive selection	4170038
155806419	155806442	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.4967576304895296	[1]	[0,0]	-8	hSpCas9	positive selection	4170039
155806295	155806318	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.3664918817540581	[2]	[1,2,2,0]	2	hSpCas9	positive selection	4234057
155803441	155803464	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	1.063019537203424	[3]	[0,3,5,4]	7	hSpCas9	positive selection	4234059
155803185	155803208	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	1.2705099844309558	[4]	[6,2,4,4]	9	hSpCas9	positive selection	4234060
155806419	155806442	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.12489715375799637	[1]	[0,0,0,0]	-2	hSpCas9	positive selection	4234061
155803441	155803464	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.17556646182563118	[3]	[3,2]	3	hSpCas9	positive selection	4297660
155803185	155803208	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.43874004310467263	[3]	[3,3]	8	hSpCas9	positive selection	4297661
155812044	155812067	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	-0.21511149093693765	[1]	[1,0]	-4	hSpCas9	positive selection	4297662
155811835	155811858	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	-0.1415470069717618	[1]	[1,0]	-3	hSpCas9	positive selection	4361914
155806530	155806553	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.27021010915867977	[2]	[1,1]	-5	hSpCas9	positive selection	4361915
155806419	155806442	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.06277177374625115	[1]	[2,0]	-1	hSpCas9	positive selection	4361916
155803702	155803724	7	-	27760321	OCIAML3	viability	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	-0.20486553945137237	[528,458]	[339,326]	-2	hSpCas9	negative selection	4438797
155806295	155806317	7	-	27760321	OCIAML3	viability	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.2661103387668999	[570,510]	[449,583]	3	hSpCas9	negative selection	4438798
155806365	155806387	7	-	27760321	OCIAML3	viability	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	0.41270303600462976	[1406,1139]	[1234,1427]	5	hSpCas9	negative selection	4438799
155811835	155811857	7	-	27760321	OCIAML3	viability	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.09531741398517712	[491,395]	[298,459]	1	hSpCas9	negative selection	4438800
155811931	155811953	7	-	27760321	OCIAML3	viability	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	0.292045969610518	[94,79]	[79,87]	3	hSpCas9	negative selection	4438801
155803702	155803724	7	-	27760321	OCIAML2	viability	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	0.3357497297281451	[528,458]	[430,597]	4	hSpCas9	negative selection	4522260
155806295	155806317	7	-	27760321	OCIAML2	viability	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.3543323589813036	[570,510]	[271,433]	-4	hSpCas9	negative selection	4522261
155806365	155806387	7	-	27760321	OCIAML2	viability	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	0.3275271438314269	[1406,1139]	[1092,1539]	4	hSpCas9	negative selection	4522262
155811835	155811857	7	-	27760321	OCIAML2	viability	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.4012179360013867	[491,395]	[412,548]	5	hSpCas9	negative selection	4522263
155811931	155811953	7	-	27760321	OCIAML2	viability	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	0.7905586778349403	[94,79]	[124,117]	9	hSpCas9	negative selection	4522264
155803702	155803724	7	-	27760321	MV411	viability	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	0.8589719817630845	[528,458]	[550,647]	6	hSpCas9	negative selection	4605723
155806295	155806317	7	-	27760321	MV411	viability	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.46175445668571075	[570,510]	[70,1121]	3	hSpCas9	negative selection	4605724
155806365	155806387	7	-	27760321	MV411	viability	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	1.6898862054359711	[1406,1139]	[3556,1404]	9	hSpCas9	negative selection	4605725
155811835	155811857	7	-	27760321	MV411	viability	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.5028210529673386	[491,395]	[230,685]	3	hSpCas9	negative selection	4605726
155811931	155811953	7	-	27760321	MV411	viability	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	-1.3490022833163904	[94,79]	[0,54]	-7	hSpCas9	negative selection	4605727
155803702	155803724	7	-	27760321	HL60	viability	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	0.3927153889910081	[528,458]	[476,582]	5	hSpCas9	negative selection	4689186
155806295	155806317	7	-	27760321	HL60	viability	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.03939892385423249	[570,510]	[439,467]	0	hSpCas9	negative selection	4689187
155806365	155806387	7	-	27760321	HL60	viability	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	0.506058711703212	[1406,1139]	[1254,1696]	6	hSpCas9	negative selection	4689188
155811835	155811857	7	-	27760321	HL60	viability	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.25747234978225897	[491,395]	[418,443]	3	hSpCas9	negative selection	4689189
155811931	155811953	7	-	27760321	HL60	viability	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	-0.08725980755416884	[94,79]	[67,65]	-1	hSpCas9	negative selection	4689190
155803702	155803724	7	-	27760321	HT1080	viability	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	1.3661079668891152	[458,357]	[323,523]	7	hSpCas9	negative selection	4772649
155806295	155806317	7	-	27760321	HT1080	viability	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.34228626949087537	[510,398]	[131,154]	-1	hSpCas9	negative selection	4772650
155806365	155806387	7	-	27760321	HT1080	viability	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	0.8498939038591784	[1139,889]	[734,721]	4	hSpCas9	negative selection	4772651
155811835	155811857	7	-	27760321	HT1080	viability	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	1.3019282350635002	[395,308]	[350,340]	7	hSpCas9	negative selection	4772652
155811931	155811953	7	-	27760321	HT1080	viability	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	-0.03125743509043799	[79,62]	[14,41]	0	hSpCas9	negative selection	4772653
155803702	155803724	7	-	27760321	HT29	viability after 7 days	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	0.41550227200370426	[458,357]	[579,762,738]	6	hSpCas9	negative selection	4856112
155806295	155806317	7	-	27760321	HT29	viability after 7 days	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.008282943166209922	[510,398]	[738,458,568]	0	hSpCas9	negative selection	4856113
155806365	155806387	7	-	27760321	HT29	viability after 7 days	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	0.29701554958248044	[1139,889]	[1919,1555,1383]	4	hSpCas9	negative selection	4856114
155811835	155811857	7	-	27760321	HT29	viability after 7 days	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.26105150333302257	[395,308]	[666,461,517]	4	hSpCas9	negative selection	4856115
155811931	155811953	7	-	27760321	HT29	viability after 7 days	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	0.7400382784919344	[79,62]	[135,163,157]	9	hSpCas9	negative selection	4856116
155803702	155803724	7	-	27760321	HT29	viability after 25 days	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	0.6159174935159486	[458,357]	[845,557,734]	7	hSpCas9	negative selection	4939575
155806295	155806317	7	-	27760321	HT29	viability after 25 days	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.21898400337996932	[510,398]	[515,650,658]	2	hSpCas9	negative selection	4939576
155806365	155806387	7	-	27760321	HT29	viability after 25 days	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	0.9651938770756274	[1139,889]	[2559,2110,2081]	9	hSpCas9	negative selection	4939577
155811835	155811857	7	-	27760321	HT29	viability after 25 days	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.25701775915860964	[395,308]	[421,467,565]	2	hSpCas9	negative selection	4939578
155811931	155811953	7	-	27760321	HT29	viability after 25 days	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	0.7164826108160103	[79,62]	[276,49,58]	7	hSpCas9	negative selection	4939579
155803702	155803724	7	-	27760321	HT29	viability after 22 days	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	0.9396129855461466	[458,357]	[1061,635,1015]	9	hSpCas9	negative selection	5023038
155806295	155806317	7	-	27760321	HT29	viability after 22 days	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.07275332325271505	[510,398]	[394,498,771]	0	hSpCas9	negative selection	5023039
155806365	155806387	7	-	27760321	HT29	viability after 22 days	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	0.6924412910121291	[1139,889]	[1855,2017,1814]	7	hSpCas9	negative selection	5023040
155811835	155811857	7	-	27760321	HT29	viability after 22 days	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.30021799675811817	[395,308]	[591,497,411]	3	hSpCas9	negative selection	5023041
155811931	155811953	7	-	27760321	HT29	viability after 22 days	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	0.5877461083843043	[79,62]	[215,71,81]	6	hSpCas9	negative selection	5023042
155803702	155803724	7	-	27760321	HT29	viability after 19 days	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	1.0874537270974305	[458,357]	[1006,790,1173]	9	hSpCas9	negative selection	5106501
155806295	155806317	7	-	27760321	HT29	viability after 19 days	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.08686845466032306	[510,398]	[420,701,344]	-1	hSpCas9	negative selection	5106502
155806365	155806387	7	-	27760321	HT29	viability after 19 days	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	0.6227098199697587	[1139,889]	[2138,1607,1655]	6	hSpCas9	negative selection	5106503
155811835	155811857	7	-	27760321	HT29	viability after 19 days	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.43251556624370485	[395,308]	[490,502,628]	4	hSpCas9	negative selection	5106504
155811931	155811953	7	-	27760321	HT29	viability after 19 days	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	-0.049730984436191505	[79,62]	[87,123,27]	0	hSpCas9	negative selection	5106505
155803702	155803724	7	-	27760321	HT29	viability after 16 days	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	0.6964618012201144	[458,357]	[853,640,739]	7	hSpCas9	negative selection	5189964
155806295	155806317	7	-	27760321	HT29	viability after 16 days	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.5537149050097874	[510,398]	[714,768,753]	6	hSpCas9	negative selection	5189965
155806365	155806387	7	-	27760321	HT29	viability after 16 days	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	0.5329853499235351	[1139,889]	[1559,1385,1981]	6	hSpCas9	negative selection	5189966
155811835	155811857	7	-	27760321	HT29	viability after 16 days	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.39014733102756977	[395,308]	[699,429,439]	4	hSpCas9	negative selection	5189967
155811931	155811953	7	-	27760321	HT29	viability after 16 days	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	0.6867656788239476	[79,62]	[175,164,48]	7	hSpCas9	negative selection	5189968
155803702	155803724	7	-	27760321	HT29	viability after 13 days	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	0.8243851453888076	[458,357]	[595,948,964]	9	hSpCas9	negative selection	5273427
155806295	155806317	7	-	27760321	HT29	viability after 13 days	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.07334783242436987	[510,398]	[574,483,603]	0	hSpCas9	negative selection	5273428
155806365	155806387	7	-	27760321	HT29	viability after 13 days	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	0.4353048392046588	[1139,889]	[1583,1506,1679]	5	hSpCas9	negative selection	5273429
155811835	155811857	7	-	27760321	HT29	viability after 13 days	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.4160174261584452	[395,308]	[367,754,515]	5	hSpCas9	negative selection	5273430
155811931	155811953	7	-	27760321	HT29	viability after 13 days	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	0.7991306134491971	[79,62]	[109,224,100]	9	hSpCas9	negative selection	5273431
155803702	155803724	7	-	27760321	HT29	viability after 10 days	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	0.31657890835362745	[458,357]	[767,427,701]	4	hSpCas9	negative selection	5356890
155806295	155806317	7	-	27760321	HT29	viability after 10 days	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.3604199951370551	[510,398]	[765,674,744]	5	hSpCas9	negative selection	5356891
155806365	155806387	7	-	27760321	HT29	viability after 10 days	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	0.5637456530556766	[1139,889]	[2238,1622,1752]	7	hSpCas9	negative selection	5356892
155811835	155811857	7	-	27760321	HT29	viability after 10 days	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.5199445330692327	[395,308]	[552,823,523]	7	hSpCas9	negative selection	5356893
155811931	155811953	7	-	27760321	HT29	viability after 10 days	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	-0.17080503535578062	[79,62]	[64,24,144]	-2	hSpCas9	negative selection	5356894
155803702	155803724	7	-	27760321	MOLM13	viability	ACTCGGTGGCGGCCAAATCGGG	SHH	ENSG00000164690	-0.18880719149818384	[528,458]	[298,196]	-1	hSpCas9	negative selection	5440353
155806295	155806317	7	-	27760321	MOLM13	viability	TCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.04022705499174084	[570,510]	[239,375]	0	hSpCas9	negative selection	5440354
155806365	155806387	7	-	27760321	MOLM13	viability	TACGGCATGCTGGCCCGCCTGG	SHH	ENSG00000164690	1.2248078197283958	[1406,1139]	[2014,1376]	8	hSpCas9	negative selection	5440355
155811835	155811857	7	-	27760321	MOLM13	viability	AGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	-0.492823629987163	[491,395]	[243,119]	-3	hSpCas9	negative selection	5440356
155811931	155811953	7	-	27760321	MOLM13	viability	CGCCAGCGGAAGGTATGAAGGG	SHH	ENSG00000164690	1.2933415631984186	[94,79]	[45,183]	8	hSpCas9	negative selection	5440357
155808758	155808781	7	+	27661255	K562	viability	GCCGGGGCCGGGCTTTGTGTCGG	SHH	ENSG00000164690	-0.23306240154096491	[483,375]	[339,253]	-6	dCas9-KRAB	negative selection	5510907
155809045	155809068	7	+	27661255	K562	viability	GCGGCTCGGGACCCCACTCCAGG	SHH	ENSG00000164690	0.3015844586185247	[479,592]	[570,487]	8	dCas9-KRAB	negative selection	5510908
155808735	155808758	7	-	27661255	K562	viability	GGCCCTGCTGGGCTTCACGGTGG	SHH	ENSG00000164690	-0.8808563206888556	[473,593]	[227,232]	-8	dCas9-KRAB	negative selection	5510909
155808816	155808839	7	-	27661255	K562	viability	GGCTCGCAGATCAGGGAGGTAGG	SHH	ENSG00000164690	0.023574788006047953	[444,485]	[412,346]	0	dCas9-KRAB	negative selection	5510910
155808820	155808843	7	-	27661255	K562	viability	GCGCGGCTCGCAGATCAGGGAGG	SHH	ENSG00000164690	0.01832823066108724	[879,801]	[775,600]	0	dCas9-KRAB	negative selection	5510911
155809095	155809118	7	-	27661255	K562	viability	GCGGCCAGGGGGCTCCTAAGGGG	SHH	ENSG00000164690	-0.07156739605083895	[826,681]	[615,540]	-3	dCas9-KRAB	negative selection	5510912
155812056	155812079	7	-	27661255	K562	viability	GCTGCTGGTATGCTCGGGACTGG	SHH	ENSG00000164690	-0.14909899120898742	[862,867]	[698,558]	-5	dCas9-KRAB	negative selection	5510913
155803441	155803464	7	-	27260156	BXPC3	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.4234184063340377	[466]	[591,688,601,746]	8	hSpCas9	negative selection	5570120
155803185	155803208	7	+	27260156	BXPC3	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.25022467862042147	[671]	[509,491,536,867]	-5	hSpCas9	negative selection	5570121
155812044	155812067	7	-	27260156	BXPC3	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.48612908128886745	[175]	[277,232,246,271]	8	hSpCas9	negative selection	5570122
155811835	155811858	7	-	27260156	BXPC3	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.32337399924323273	[108]	[130,209,110,109]	7	hSpCas9	negative selection	5634374
155806530	155806553	7	-	27260156	BXPC3	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.245243444629658	[397]	[332,272,323,495]	-5	hSpCas9	negative selection	5634375
155806419	155806442	7	-	27260156	BXPC3	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.18694222989289022	[195]	[162,207,132,218]	-4	hSpCas9	negative selection	5634376
155803441	155803464	7	-	27260156	A673	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.23360533063720174	[466]	[805,610,604,630]	5	hSpCas9	negative selection	5691371
155803185	155803208	7	+	27260156	A673	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.06989747644333627	[671]	[789,675,792,821]	-2	hSpCas9	negative selection	5691372
155812044	155812067	7	-	27260156	A673	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.41694091364784813	[175]	[254,282,240,349]	8	hSpCas9	negative selection	5691373
155811835	155811858	7	-	27260156	A673	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.3281849231105525	[108]	[218,118,182,141]	7	hSpCas9	negative selection	5755625
155806530	155806553	7	-	27260156	A673	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.23039098493398982	[397]	[489,269,431,451]	-5	hSpCas9	negative selection	5755626
155806419	155806442	7	-	27260156	A673	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.021375655011772077	[195]	[380,177,226,183]	0	hSpCas9	negative selection	5755627
155803441	155803464	7	-	27260156	A375	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.3045541613501168	[466]	[495,841,636,731]	4	hSpCas9	negative selection	5812622
155803185	155803208	7	+	27260156	A375	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.23033838429693404	[671]	[738,716,658,576]	-3	hSpCas9	negative selection	5812623
155812044	155812067	7	-	27260156	A375	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.5366627385911185	[175]	[324,536,193,182]	7	hSpCas9	negative selection	5812624
155811835	155811858	7	-	27260156	A375	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.5640272139556968	[108]	[101,323,124,215]	8	hSpCas9	negative selection	5876876
155806530	155806553	7	-	27260156	A375	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.13898140881828472	[397]	[362,617,413,329]	-2	hSpCas9	negative selection	5876877
155806419	155806442	7	-	27260156	A375	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.02688267985568893	[195]	[235,204,335,159]	0	hSpCas9	negative selection	5876878
155803441	155803464	7	-	27260156	COLO741	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.35736512737704046	[466]	[840,819,645]	7	hSpCas9	negative selection	5933873
155803185	155803208	7	+	27260156	COLO741	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.2728408516772431	[671]	[871,675,603]	-5	hSpCas9	negative selection	5933874
155812044	155812067	7	-	27260156	COLO741	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	-0.6178324825400012	[175]	[187,125,129]	-8	hSpCas9	negative selection	5933875
155811835	155811858	7	-	27260156	COLO741	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.04312884874081524	[108]	[100,186,138]	0	hSpCas9	negative selection	5998127
155806530	155806553	7	-	27260156	COLO741	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.08225334440038076	[397]	[655,394,408]	-2	hSpCas9	negative selection	5998128
155806419	155806442	7	-	27260156	COLO741	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.039520263973083614	[195]	[163,359,202]	-1	hSpCas9	negative selection	5998129
155803441	155803464	7	-	27260156	CAL120	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.18134025915944013	[466]	[1053,431,551]	2	hSpCas9	negative selection	6055124
155803185	155803208	7	+	27260156	CAL120	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.17115576175272007	[671]	[1258,1115,504]	2	hSpCas9	negative selection	6055125
155812044	155812067	7	-	27260156	CAL120	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.4846758329999903	[175]	[228,394,283]	7	hSpCas9	negative selection	6055126
155811835	155811858	7	-	27260156	CAL120	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.7060551827251922	[108]	[203,172,282]	9	hSpCas9	negative selection	6119378
155806530	155806553	7	-	27260156	CAL120	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.4968462789126482	[397]	[261,348,426]	-6	hSpCas9	negative selection	6119379
155806419	155806442	7	-	27260156	CAL120	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.46961763906296006	[195]	[236,208,92]	-6	hSpCas9	negative selection	6119380
155803441	155803464	7	-	27260156	CADOES1	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.491046675648458	[466]	[492,509,670,773]	7	hSpCas9	negative selection	6176375
155803185	155803208	7	+	27260156	CADOES1	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.4463305380787319	[671]	[484,367,458,524]	-7	hSpCas9	negative selection	6176376
155812044	155812067	7	-	27260156	CADOES1	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.17692352553126445	[175]	[177,237,223,96]	3	hSpCas9	negative selection	6176377
155811835	155811858	7	-	27260156	CADOES1	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	-0.5246653011371292	[108]	[93,48,36,102]	-7	hSpCas9	negative selection	6240629
155806530	155806553	7	-	27260156	CADOES1	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.0172743369780248	[397]	[309,457,389,302]	0	hSpCas9	negative selection	6240630
155806419	155806442	7	-	27260156	CADOES1	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.09750243625669297	[195]	[208,178,249,139]	1	hSpCas9	negative selection	6240631
155803441	155803464	7	-	27260156	EWS502	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.4774339513940424	[466]	[499,849,663,758]	8	hSpCas9	negative selection	6297626
155803185	155803208	7	+	27260156	EWS502	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.1313063632776783	[671]	[584,464,754,820]	-2	hSpCas9	negative selection	6297627
155812044	155812067	7	-	27260156	EWS502	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.7741504077694104	[175]	[185,240,413,463]	9	hSpCas9	negative selection	6297628
155811835	155811858	7	-	27260156	EWS502	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.8051829471017637	[108]	[122,122,249,332]	9	hSpCas9	negative selection	6361880
155806530	155806553	7	-	27260156	EWS502	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.06661369282925164	[397]	[298,313,493,527]	-1	hSpCas9	negative selection	6361881
155806419	155806442	7	-	27260156	EWS502	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.3119005377710504	[195]	[300,207,108,417]	5	hSpCas9	negative selection	6361882
155803441	155803464	7	-	27260156	EW8	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.5671263905547869	[466]	[575,419,649,580]	8	hSpCas9	negative selection	6418877
155803185	155803208	7	+	27260156	EW8	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.1042684745895075	[671]	[658,671,512,516]	2	hSpCas9	negative selection	6418878
155812044	155812067	7	-	27260156	EW8	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.24801378440329125	[175]	[207,193,112,175]	4	hSpCas9	negative selection	6418879
155811835	155811858	7	-	27260156	EW8	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.26627323666532465	[108]	[121,109,84,112]	5	hSpCas9	negative selection	6483131
155806530	155806553	7	-	27260156	EW8	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.06068695500616986	[397]	[410,309,306,219]	-1	hSpCas9	negative selection	6483132
155806419	155806442	7	-	27260156	EW8	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.051650498272754364	[195]	[158,162,88,258]	0	hSpCas9	negative selection	6483133
155803441	155803464	7	-	27260156	CORL105	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.5508597865349393	[466]	[937,628,967,702]	8	hSpCas9	negative selection	6540128
155803185	155803208	7	+	27260156	CORL105	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.0999215736852046	[671]	[991,813,865,709]	1	hSpCas9	negative selection	6540129
155812044	155812067	7	-	27260156	CORL105	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.357504856846494	[175]	[290,226,354,198]	6	hSpCas9	negative selection	6540130
155811835	155811858	7	-	27260156	CORL105	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.6686643178245326	[108]	[178,155,345,152]	9	hSpCas9	negative selection	6604382
155806530	155806553	7	-	27260156	CORL105	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.24596754493935816	[397]	[307,402,373,479]	-4	hSpCas9	negative selection	6604383
155806419	155806442	7	-	27260156	CORL105	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.3501905477907943	[195]	[237,154,138,183]	-6	hSpCas9	negative selection	6604384
155803441	155803464	7	-	27260156	HS294T	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.43026227945538037	[466]	[180,202,341,255]	6	hSpCas9	negative selection	6661379
155803185	155803208	7	+	27260156	HS294T	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.47792039216426363	[671]	[123,136,287,207]	-6	hSpCas9	negative selection	6661380
155812044	155812067	7	-	27260156	HS294T	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.15030214014219379	[175]	[59,116,58,63]	2	hSpCas9	negative selection	6661381
155811835	155811858	7	-	27260156	HS294T	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.2768148411426361	[108]	[49,45,48,60]	4	hSpCas9	negative selection	6725633
155806530	155806553	7	-	27260156	HS294T	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.3888699370800639	[397]	[103,86,138,146]	-5	hSpCas9	negative selection	6725634
155806419	155806442	7	-	27260156	HS294T	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.642151872862578	[195]	[305,35,37,68]	8	hSpCas9	negative selection	6725635
155803441	155803464	7	-	27260156	HCC44	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.3746175406517816	[466]	[581,506,739,921]	6	hSpCas9	negative selection	6782630
155803185	155803208	7	+	27260156	HCC44	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.16702374246222607	[671]	[1018,700,975,770]	2	hSpCas9	negative selection	6782631
155812044	155812067	7	-	27260156	HCC44	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.41791631387860195	[175]	[336,96,385,291]	7	hSpCas9	negative selection	6782632
155811835	155811858	7	-	27260156	HCC44	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	-0.48359454012098313	[108]	[100,126,50,62]	-6	hSpCas9	negative selection	6846884
155806530	155806553	7	-	27260156	HCC44	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.16916490021112543	[397]	[568,404,304,319]	-3	hSpCas9	negative selection	6846885
155806419	155806442	7	-	27260156	HCC44	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.05027747029392704	[195]	[141,206,270,237]	-1	hSpCas9	negative selection	6846886
155803441	155803464	7	-	27260156	G402	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.5728311097633632	[466]	[803,1483,392,741]	7	hSpCas9	negative selection	6903881
155803185	155803208	7	+	27260156	G402	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.05633708481137989	[671]	[711,703,882,833]	0	hSpCas9	negative selection	6903882
155812044	155812067	7	-	27260156	G402	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.3972113755591884	[175]	[186,293,352,282]	5	hSpCas9	negative selection	6903883
155811835	155811858	7	-	27260156	G402	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	1.0450880477959337	[108]	[359,428,243,93]	9	hSpCas9	negative selection	6968135
155806530	155806553	7	-	27260156	G402	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.4257707156795666	[397]	[463,284,215,483]	-5	hSpCas9	negative selection	6968136
155806419	155806442	7	-	27260156	G402	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.3845532603810955	[195]	[383,163,92,121]	-5	hSpCas9	negative selection	6968137
155803441	155803464	7	-	27260156	L33	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.5196327075924552	[466]	[741,300,332,668]	9	hSpCas9	negative selection	7025132
155803185	155803208	7	+	27260156	L33	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.13862999396994624	[671]	[742,279,570,625]	3	hSpCas9	negative selection	7025133
155812044	155812067	7	-	27260156	L33	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.19697024297749843	[175]	[224,65,142,192]	4	hSpCas9	negative selection	7025134
155811835	155811858	7	-	27260156	L33	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.08752774543197717	[108]	[140,46,65,101]	2	hSpCas9	negative selection	7089386
155806530	155806553	7	-	27260156	L33	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.21133472103608417	[397]	[380,110,189,418]	-5	hSpCas9	negative selection	7089387
155806419	155806442	7	-	27260156	L33	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.46654029261675367	[195]	[165,59,37,192]	-8	hSpCas9	negative selection	7089388
155803441	155803464	7	-	27260156	K562	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.9065266254626342	[466]	[989,885,782,500]	9	hSpCas9	negative selection	7146383
155803185	155803208	7	+	27260156	K562	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.013752290039788395	[671]	[650,499,817,452]	0	hSpCas9	negative selection	7146384
155812044	155812067	7	-	27260156	K562	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.9842284763822948	[175]	[445,180,273,334]	9	hSpCas9	negative selection	7146385
155811835	155811858	7	-	27260156	K562	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	-0.48552585828694816	[108]	[41,47,2,167]	-5	hSpCas9	negative selection	7210637
155806530	155806553	7	-	27260156	K562	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.7095693900091656	[397]	[225,141,219,265]	-7	hSpCas9	negative selection	7210638
155806419	155806442	7	-	27260156	K562	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.3853051043453861	[195]	[52,54,228,178]	-5	hSpCas9	negative selection	7210639
155803441	155803464	7	-	27260156	HT29	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.2535342385616384	[466]	[612,615,624,819]	5	hSpCas9	negative selection	7267634
155803185	155803208	7	+	27260156	HT29	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.21997356174514077	[671]	[744,790,740,552]	-4	hSpCas9	negative selection	7267635
155812044	155812067	7	-	27260156	HT29	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.05107241318569722	[175]	[227,298,231,142]	1	hSpCas9	negative selection	7267636
155811835	155811858	7	-	27260156	HT29	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.43613024929232447	[108]	[263,218,128,120]	8	hSpCas9	negative selection	7331888
155806530	155806553	7	-	27260156	HT29	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.4452666227821973	[397]	[418,468,356,206]	-7	hSpCas9	negative selection	7331889
155806419	155806442	7	-	27260156	HT29	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.15392789658063522	[195]	[358,122,212,168]	-3	hSpCas9	negative selection	7331890
155803441	155803464	7	-	27260156	MHHES1	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.30689451706407134	[466]	[359,926,671,626]	5	hSpCas9	negative selection	7388885
155803185	155803208	7	+	27260156	MHHES1	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.260350035698452	[671]	[728,830,447,553]	-5	hSpCas9	negative selection	7388886
155812044	155812067	7	-	27260156	MHHES1	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.49583755757958425	[175]	[299,314,352,174]	8	hSpCas9	negative selection	7388887
155811835	155811858	7	-	27260156	MHHES1	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.3924078613749875	[108]	[111,177,181,163]	7	hSpCas9	negative selection	7453139
155806530	155806553	7	-	27260156	MHHES1	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	0.20107687987747275	[397]	[464,374,826,392]	3	hSpCas9	negative selection	7453140
155806419	155806442	7	-	27260156	MHHES1	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.10115708821328995	[195]	[139,431,134,240]	1	hSpCas9	negative selection	7453141
155803441	155803464	7	-	27260156	MEWO	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.38351972302310217	[466]	[713,496,526]	7	hSpCas9	negative selection	7510136
155803185	155803208	7	+	27260156	MEWO	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.20684931970680875	[671]	[962,661,597]	4	hSpCas9	negative selection	7510137
155812044	155812067	7	-	27260156	MEWO	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.6918766577399265	[175]	[228,416,143]	9	hSpCas9	negative selection	7510138
155811835	155811858	7	-	27260156	MEWO	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.5997060399161489	[108]	[141,183,134]	9	hSpCas9	negative selection	7574390
155806530	155806553	7	-	27260156	MEWO	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.2273107310425211	[397]	[388,295,282]	-5	hSpCas9	negative selection	7574391
155806419	155806442	7	-	27260156	MEWO	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.2638712605296245	[195]	[228,132,110]	-5	hSpCas9	negative selection	7574392
155803441	155803464	7	-	27260156	LNCAPCLONEFGC	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.38875017483114094	[466]	[577,530,633,484]	6	hSpCas9	negative selection	7631387
155803185	155803208	7	+	27260156	LNCAPCLONEFGC	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.355248441819778	[671]	[482,485,513,424]	-5	hSpCas9	negative selection	7631388
155812044	155812067	7	-	27260156	LNCAPCLONEFGC	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.5026889154638392	[175]	[164,345,261,128]	7	hSpCas9	negative selection	7631389
155811835	155811858	7	-	27260156	LNCAPCLONEFGC	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	-0.028274054546103322	[108]	[77,46,164,110]	0	hSpCas9	negative selection	7695641
155806530	155806553	7	-	27260156	LNCAPCLONEFGC	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.3195840822524778	[397]	[331,203,361,272]	-5	hSpCas9	negative selection	7695642
155806419	155806442	7	-	27260156	LNCAPCLONEFGC	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.2550730537636394	[195]	[155,112,153,174]	-4	hSpCas9	negative selection	7695643
155803441	155803464	7	-	27260156	PANC0327	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.5630977698504529	[466]	[707,566,543,645]	8	hSpCas9	negative selection	7752638
155803185	155803208	7	+	27260156	PANC0327	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.005341364775948265	[671]	[865,462,558,529]	0	hSpCas9	negative selection	7752639
155812044	155812067	7	-	27260156	PANC0327	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.368537229845711	[175]	[89,186,208,313]	5	hSpCas9	negative selection	7752640
155811835	155811858	7	-	27260156	PANC0327	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.22189312114980964	[108]	[154,89,78,133]	3	hSpCas9	negative selection	7816892
155806530	155806553	7	-	27260156	PANC0327	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.3667599194974417	[397]	[434,139,207,343]	-5	hSpCas9	negative selection	7816893
155806419	155806442	7	-	27260156	PANC0327	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.5949392294661384	[195]	[125,74,68,196]	-7	hSpCas9	negative selection	7816894
155803441	155803464	7	-	27260156	NCIH2009	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.4838317046725961	[466]	[994,808,949]	6	hSpCas9	negative selection	7873889
155803185	155803208	7	+	27260156	NCIH2009	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.3050230588772608	[671]	[1332,1107,1071]	4	hSpCas9	negative selection	7873890
155812044	155812067	7	-	27260156	NCIH2009	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	-0.3686177470461556	[175]	[148,126,287]	-5	hSpCas9	negative selection	7873891
155811835	155811858	7	-	27260156	NCIH2009	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.530176038462054	[108]	[370,178,139]	7	hSpCas9	negative selection	7938143
155806530	155806553	7	-	27260156	NCIH2009	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.3415055392162254	[397]	[539,373,422]	-4	hSpCas9	negative selection	7938144
155806419	155806442	7	-	27260156	NCIH2009	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.05622716282022244	[195]	[439,305,137]	0	hSpCas9	negative selection	7938145
155803441	155803464	7	-	27260156	NCIH1373	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.09849819614961346	[466]	[560,691,547,108]	1	hSpCas9	negative selection	7995140
155803185	155803208	7	+	27260156	NCIH1373	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.17477317144148063	[671]	[802,766,426,179]	-2	hSpCas9	negative selection	7995141
155812044	155812067	7	-	27260156	NCIH1373	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.24908657878801366	[175]	[146,228,281,69]	2	hSpCas9	negative selection	7995142
155811835	155811858	7	-	27260156	NCIH1373	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	2.1902598020363624	[108]	[835,168,1122,38]	9	hSpCas9	negative selection	8059394
155806530	155806553	7	-	27260156	NCIH1373	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.5575965550687445	[397]	[285,325,320,70]	-5	hSpCas9	negative selection	8059395
155806419	155806442	7	-	27260156	NCIH1373	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.7477024265547496	[195]	[114,233,84,18]	-6	hSpCas9	negative selection	8059396
155803441	155803464	7	-	27260156	PATU8902	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.6606159313774198	[466]	[1335,743,828,1270]	7	hSpCas9	negative selection	8116391
155803185	155803208	7	+	27260156	PATU8902	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.03593442892638182	[671]	[1101,752,626,1276]	0	hSpCas9	negative selection	8116392
155812044	155812067	7	-	27260156	PATU8902	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	-0.8889898371808207	[175]	[86,161,32,291]	-7	hSpCas9	negative selection	8116393
155811835	155811858	7	-	27260156	PATU8902	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	-0.5190855403810404	[108]	[42,193,104,78]	-5	hSpCas9	negative selection	8180645
155806530	155806553	7	-	27260156	PATU8902	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	0.16674726150108302	[397]	[670,632,622,546]	1	hSpCas9	negative selection	8180646
155806419	155806442	7	-	27260156	PATU8902	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.5294444339246324	[195]	[514,108,381,590]	5	hSpCas9	negative selection	8180647
155803441	155803464	7	-	27260156	PANC1	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.405434871299956	[466]	[567,620,486,467]	6	hSpCas9	negative selection	8237642
155803185	155803208	7	+	27260156	PANC1	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.10032657476212803	[671]	[522,740,605,348]	-2	hSpCas9	negative selection	8237643
155812044	155812067	7	-	27260156	PANC1	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	-0.242987182156283	[175]	[133,114,95,155]	-4	hSpCas9	negative selection	8237644
155811835	155811858	7	-	27260156	PANC1	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.9020924752944586	[108]	[160,177,45,291]	9	hSpCas9	negative selection	8301896
155806530	155806553	7	-	27260156	PANC1	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.13311040477171762	[397]	[343,471,240,229]	-2	hSpCas9	negative selection	8301897
155806419	155806442	7	-	27260156	PANC1	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.21557581452417418	[195]	[186,172,137,92]	-3	hSpCas9	negative selection	8301898
155803441	155803464	7	-	27260156	PANC0813	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.6034529422334377	[466]	[1008,721,672,937]	8	hSpCas9	negative selection	8358893
155803185	155803208	7	+	27260156	PANC0813	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.22824973514575397	[671]	[1124,927,775,887]	3	hSpCas9	negative selection	8358894
155812044	155812067	7	-	27260156	PANC0813	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.5310075812796672	[175]	[416,266,256,265]	8	hSpCas9	negative selection	8358895
155811835	155811858	7	-	27260156	PANC0813	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.8098955436534105	[108]	[252,234,188,222]	9	hSpCas9	negative selection	8423147
155806530	155806553	7	-	27260156	PANC0813	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.45947772754441873	[397]	[311,418,190,428]	-6	hSpCas9	negative selection	8423148
155806419	155806442	7	-	27260156	PANC0813	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.5012871296086672	[195]	[171,279,129,73]	-6	hSpCas9	negative selection	8423149
155803441	155803464	7	-	27260156	RDES	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.33004114311424626	[466]	[577,649,704,787]	5	hSpCas9	negative selection	8480144
155803185	155803208	7	+	27260156	RDES	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.27828151825797454	[671]	[652,625,590,654]	-5	hSpCas9	negative selection	8480145
155812044	155812067	7	-	27260156	RDES	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.027696765918312716	[175]	[156,271,181,211]	0	hSpCas9	negative selection	8480146
155811835	155811858	7	-	27260156	RDES	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.46452047654759787	[108]	[109,204,217,164]	7	hSpCas9	negative selection	8544398
155806530	155806553	7	-	27260156	RDES	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.10034556969936356	[397]	[334,410,496,484]	-2	hSpCas9	negative selection	8544399
155806419	155806442	7	-	27260156	RDES	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.014801812147832383	[195]	[132,369,122,267]	0	hSpCas9	negative selection	8544400
155803441	155803464	7	-	27260156	PC3	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.08928668567558586	[466]	[273,546,831,509]	2	hSpCas9	negative selection	8601395
155803185	155803208	7	+	27260156	PC3	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.1510837299444081	[671]	[486,265,1112,750]	-3	hSpCas9	negative selection	8601396
155812044	155812067	7	-	27260156	PC3	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.09619881950883613	[175]	[131,162,422,126]	2	hSpCas9	negative selection	8601397
155811835	155811858	7	-	27260156	PC3	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	-0.6066139160500152	[108]	[32,66,121,95]	-8	hSpCas9	negative selection	8665649
155806530	155806553	7	-	27260156	PC3	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.2988360828766141	[397]	[187,328,611,301]	-6	hSpCas9	negative selection	8665650
155806419	155806442	7	-	27260156	PC3	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.3756128757502242	[195]	[86,80,348,182]	-7	hSpCas9	negative selection	8665651
155803441	155803464	7	-	27260156	PATU8988T	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	-0.04536187957536654	[466]	[304,600,407,451]	-1	hSpCas9	negative selection	8722646
155803185	155803208	7	+	27260156	PATU8988T	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.2943549729226359	[671]	[387,601,512,629]	-5	hSpCas9	negative selection	8722647
155812044	155812067	7	-	27260156	PATU8988T	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.4361709411398925	[175]	[240,245,128,313]	7	hSpCas9	negative selection	8722648
155811835	155811858	7	-	27260156	PATU8988T	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.30160647362461934	[108]	[115,211,96,99]	5	hSpCas9	negative selection	8786900
155806530	155806553	7	-	27260156	PATU8988T	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	0.6731805084655843	[397]	[732,844,298,600]	9	hSpCas9	negative selection	8786901
155806419	155806442	7	-	27260156	PATU8988T	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.13326125854723303	[195]	[173,231,137,150]	-2	hSpCas9	negative selection	8786902
155803441	155803464	7	-	27260156	T47D	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.36657357047549005	[466]	[799,548,709,761]	7	hSpCas9	negative selection	8843897
155803185	155803208	7	+	27260156	T47D	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.13317627515202424	[671]	[673,729,657,794]	-3	hSpCas9	negative selection	8843898
155812044	155812067	7	-	27260156	T47D	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.4010199671856265	[175]	[341,178,272,297]	8	hSpCas9	negative selection	8843899
155811835	155811858	7	-	27260156	T47D	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.13613362845321886	[108]	[140,151,69,196]	3	hSpCas9	negative selection	8908151
155806530	155806553	7	-	27260156	T47D	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.051606510015947266	[397]	[492,475,355,463]	-1	hSpCas9	negative selection	8908152
155806419	155806442	7	-	27260156	T47D	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.06606540060386701	[195]	[273,202,210,184]	-1	hSpCas9	negative selection	8908153
155803441	155803464	7	-	27260156	SU8686	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.4843732404380529	[466]	[695,611,582,700]	7	hSpCas9	negative selection	8965148
155803185	155803208	7	+	27260156	SU8686	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.14739141344182527	[671]	[924,566,730,720]	2	hSpCas9	negative selection	8965149
155812044	155812067	7	-	27260156	SU8686	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.5678012325655889	[175]	[312,239,306,152]	8	hSpCas9	negative selection	8965150
155811835	155811858	7	-	27260156	SU8686	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.9436590390763868	[108]	[145,216,243,233]	9	hSpCas9	negative selection	9029402
155806530	155806553	7	-	27260156	SU8686	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.3937526119911955	[397]	[312,264,317,307]	-6	hSpCas9	negative selection	9029403
155806419	155806442	7	-	27260156	SU8686	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.3569125964249589	[195]	[135,152,103,224]	-5	hSpCas9	negative selection	9029404
155803441	155803464	7	-	27260156	SKES1	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.4172653126209709	[466]	[559,682,661,579]	8	hSpCas9	negative selection	9086399
155803185	155803208	7	+	27260156	SKES1	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.1559137301295176	[671]	[1053,497,460,456]	-3	hSpCas9	negative selection	9086400
155812044	155812067	7	-	27260156	SKES1	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.33235261397901894	[175]	[166,263,274,177]	7	hSpCas9	negative selection	9086401
155811835	155811858	7	-	27260156	SKES1	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	-0.45044000771538384	[108]	[126,53,68,71]	-7	hSpCas9	negative selection	9150653
155806530	155806553	7	-	27260156	SKES1	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.08081912654556364	[397]	[413,417,290,384]	-2	hSpCas9	negative selection	9150654
155806419	155806442	7	-	27260156	SKES1	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.4803895172318198	[195]	[202,192,85,97]	-8	hSpCas9	negative selection	9150655
155803441	155803464	7	-	27260156	TOV112D	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.1555962167788781	[466]	[484,740,560,351]	3	hSpCas9	negative selection	9207650
155803185	155803208	7	+	27260156	TOV112D	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.05592623392657592	[671]	[544,740,628,686]	-1	hSpCas9	negative selection	9207651
155812044	155812067	7	-	27260156	TOV112D	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.7804487003478137	[175]	[219,401,409,198]	9	hSpCas9	negative selection	9207652
155811835	155811858	7	-	27260156	TOV112D	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	-0.07277417620118598	[108]	[139,87,111,74]	-1	hSpCas9	negative selection	9271904
155806530	155806553	7	-	27260156	TOV112D	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.09337187491502288	[397]	[291,379,456,359]	-2	hSpCas9	negative selection	9271905
155806419	155806442	7	-	27260156	TOV112D	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.1448220350069156	[195]	[368,289,75,164]	3	hSpCas9	negative selection	9271906
155803441	155803464	7	-	27260156	TC71	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.2008379419025768	[466]	[514,540,585,665]	5	hSpCas9	negative selection	9328901
155803185	155803208	7	+	27260156	TC71	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	-0.10530502239328932	[671]	[584,720,586,797]	-3	hSpCas9	negative selection	9328902
155812044	155812067	7	-	27260156	TC71	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.059404270308742735	[175]	[202,202,219,156]	1	hSpCas9	negative selection	9328903
155811835	155811858	7	-	27260156	TC71	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	-0.08104030810986496	[108]	[85,98,127,129]	-2	hSpCas9	negative selection	9393155
155806530	155806553	7	-	27260156	TC71	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	-0.01570747239803702	[397]	[304,411,472,503]	0	hSpCas9	negative selection	9393156
155806419	155806442	7	-	27260156	TC71	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.34738822595422514	[195]	[158,149,165,186]	-7	hSpCas9	negative selection	9393157
155803441	155803464	7	-	27260156	TC32	viability	CCGCACAACGACTCGGCCACCGG	SHH	ENSG00000164690	0.4397306036815482	[466]	[424,424,840,796]	7	hSpCas9	negative selection	9450152
155803185	155803208	7	+	27260156	TC32	viability	CTCGATGACCGCGTAGCACGAGG	SHH	ENSG00000164690	0.024223548963899	[671]	[578,676,671,594]	0	hSpCas9	negative selection	9450153
155812044	155812067	7	-	27260156	TC32	viability	CTCGGGACTGGCGTGCGGACCGG	SHH	ENSG00000164690	0.015946661613888358	[175]	[174,116,263,135]	0	hSpCas9	negative selection	9450154
155811835	155811858	7	-	27260156	TC32	viability	AAGAAAACACCGGAGCGGACAGG	SHH	ENSG00000164690	0.6953757631215904	[108]	[103,98,235,266]	9	hSpCas9	negative selection	9514406
155806530	155806553	7	-	27260156	TC32	viability	TAAGGACAAGTTGAACGCTTTGG	SHH	ENSG00000164690	0.03865079015870984	[397]	[315,298,622,356]	0	hSpCas9	negative selection	9514407
155806419	155806442	7	-	27260156	TC32	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.08243722997447489	[195]	[184,111,178,235]	-1	hSpCas9	negative selection	9514408
155800616	155800639	7	-	27869803	HPAFII	viability after 27 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	0.11866332854781592	[146]	[156,22,NaN]	0	hSpCas9	negative selection	9598844
155802907	155802930	7	+	27869803	HPAFII	viability after 27 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	0.16189778227742002	[265]	[90,210,NaN]	1	hSpCas9	negative selection	9598845
155806295	155806318	7	-	27869803	HPAFII	viability after 27 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.1922544212812249	[210]	[125,72,NaN]	-1	hSpCas9	negative selection	9598846
155806491	155806514	7	+	27869803	HPAFII	viability after 27 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.48756153897485555	[202]	[111,180,NaN]	4	hSpCas9	negative selection	9598847
155806699	155806722	7	+	27869803	HPAFII	viability after 27 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	-1.7309919534967608	[317]	[57,43,NaN]	-8	hSpCas9	negative selection	9598848
155812068	155812091	7	+	27869803	HPAFII	viability after 27 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.8487785780905899	[449]	[174,94,NaN]	-5	hSpCas9	negative selection	9598849
155800616	155800639	7	-	27869803	HPAFII	viability after 15 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-0.05131552092965774	[146]	[305,56,NaN]	0	hSpCas9	negative selection	9681293
155802907	155802930	7	+	27869803	HPAFII	viability after 15 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	0.41610212012276143	[265]	[230,474,NaN]	5	hSpCas9	negative selection	9681294
155806295	155806318	7	-	27869803	HPAFII	viability after 15 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.1532883295518614	[210]	[311,214,NaN]	1	hSpCas9	negative selection	9681295
155806491	155806514	7	+	27869803	HPAFII	viability after 15 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	-0.07004739248219227	[202]	[176,226,NaN]	0	hSpCas9	negative selection	9681296
155806699	155806722	7	+	27869803	HPAFII	viability after 15 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	-1.0243122510683693	[317]	[270,103,NaN]	-8	hSpCas9	negative selection	9681297
155812068	155812091	7	+	27869803	HPAFII	viability after 15 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.4594177044463738	[449]	[524,243,NaN]	-5	hSpCas9	negative selection	9681298
155800616	155800639	7	-	27869803	ASPC1	viability after 36 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	0.16890791801076366	[307]	[214,176,8]	1	hSpCas9	negative selection	9763742
155802907	155802930	7	+	27869803	ASPC1	viability after 36 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	1.235199228025212	[552]	[309,170,775]	9	hSpCas9	negative selection	9763743
155806295	155806318	7	-	27869803	ASPC1	viability after 36 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.07073346596831714	[744]	[204,475,156]	0	hSpCas9	negative selection	9763744
155806491	155806514	7	+	27869803	ASPC1	viability after 36 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.6217872343776257	[395]	[203,317,132]	6	hSpCas9	negative selection	9763745
155806699	155806722	7	+	27869803	ASPC1	viability after 36 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	1.149837667100671	[772]	[250,602,832]	9	hSpCas9	negative selection	9763746
155812068	155812091	7	+	27869803	ASPC1	viability after 36 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	1.2389802416042415	[692]	[984,781,106]	9	hSpCas9	negative selection	9763747
155800616	155800639	7	-	27869803	PATU8988S	viability after 35 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	0.8626511076011265	[212]	[151,159,NaN]	8	hSpCas9	negative selection	9846191
155802907	155802930	7	+	27869803	PATU8988S	viability after 35 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.04453711818172948	[466]	[123,240,NaN]	0	hSpCas9	negative selection	9846192
155806295	155806318	7	-	27869803	PATU8988S	viability after 35 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.03698960887431274	[713]	[308,280,NaN]	0	hSpCas9	negative selection	9846193
155806491	155806514	7	+	27869803	PATU8988S	viability after 35 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.17622949572681376	[416]	[87,291,NaN]	2	hSpCas9	negative selection	9846194
155806699	155806722	7	+	27869803	PATU8988S	viability after 35 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	-0.09353153930062541	[774]	[308,275,NaN]	-1	hSpCas9	negative selection	9846195
155812068	155812091	7	+	27869803	PATU8988S	viability after 35 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.498571605605032	[876]	[508,488,NaN]	5	hSpCas9	negative selection	9846196
155800616	155800639	7	-	27869803	PATU8988S	viability after 31 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	0.72258200402649	[212]	[89,203,NaN]	8	hSpCas9	negative selection	9928640
155802907	155802930	7	+	27869803	PATU8988S	viability after 31 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	0.39978670902646246	[466]	[213,285,NaN]	5	hSpCas9	negative selection	9928641
155806295	155806318	7	-	27869803	PATU8988S	viability after 31 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.2351800057330216	[713]	[229,256,NaN]	-3	hSpCas9	negative selection	9928642
155806491	155806514	7	+	27869803	PATU8988S	viability after 31 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.09327090546346639	[416]	[84,294,NaN]	1	hSpCas9	negative selection	9928643
155806699	155806722	7	+	27869803	PATU8988S	viability after 31 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	0.019655882318100004	[774]	[241,403,NaN]	0	hSpCas9	negative selection	9928644
155812068	155812091	7	+	27869803	PATU8988S	viability after 31 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.03263952718465657	[876]	[318,370,NaN]	0	hSpCas9	negative selection	9928645
155800616	155800639	7	-	27869803	HPAFII	viability after 35 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	-0.24810910715132606	[146]	[88,32,NaN]	-1	hSpCas9	negative selection	10011089
155802907	155802930	7	+	27869803	HPAFII	viability after 35 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.05135253647164403	[265]	[33,237,NaN]	0	hSpCas9	negative selection	10011090
155806295	155806318	7	-	27869803	HPAFII	viability after 35 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	0.6369216587498937	[210]	[254,65,NaN]	4	hSpCas9	negative selection	10011091
155806491	155806514	7	+	27869803	HPAFII	viability after 35 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.7424868416280039	[202]	[162,181,NaN]	5	hSpCas9	negative selection	10011092
155806699	155806722	7	+	27869803	HPAFII	viability after 35 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	-2.246185558092494	[317]	[16,52,NaN]	-8	hSpCas9	negative selection	10011093
155812068	155812091	7	+	27869803	HPAFII	viability after 35 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.5205680826811695	[449]	[123,197,NaN]	-3	hSpCas9	negative selection	10011094
155800616	155800639	7	-	27869803	HPAFII	viability after 31 days	CAATCTCGGAGGAAGTGCGATGG	SHH	ENSG00000164690	0.05744508395366499	[146]	[115,52,NaN]	0	hSpCas9	negative selection	10093538
155802907	155802930	7	+	27869803	HPAFII	viability after 31 days	GACTTGACCGCCATGCCCAGCGG	SHH	ENSG00000164690	-0.028843555222439754	[265]	[108,186,NaN]	0	hSpCas9	negative selection	10093539
155806295	155806318	7	-	27869803	HPAFII	viability after 31 days	ATCCACTGCTCGGTGAAAGCAGG	SHH	ENSG00000164690	-0.10029179300026683	[210]	[131,86,NaN]	0	hSpCas9	negative selection	10093540
155806491	155806514	7	+	27869803	HPAFII	viability after 31 days	GCAGTTTCACTCCTGGCCACTGG	SHH	ENSG00000164690	0.6983022624249848	[202]	[136,236,NaN]	5	hSpCas9	negative selection	10093541
155806699	155806722	7	+	27869803	HPAFII	viability after 31 days	GCCCAGACACACCGAAGAGCCGG	SHH	ENSG00000164690	-1.5791624445099266	[317]	[75,41,NaN]	-7	hSpCas9	negative selection	10093542
155812068	155812091	7	+	27869803	HPAFII	viability after 31 days	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.31421135502825404	[449]	[149,260,NaN]	-2	hSpCas9	negative selection	10093543
155811840	155811863	7	-	28162770	P31FUJ	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	0.8741129995021334	[116]	[251]	8	hSpCas9	negative selection	10233891
155806449	155806472	7	-	28162770	P31FUJ	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	0.09687539007791868	[556]	[699]	1	hSpCas9	negative selection	10233892
155806430	155806453	7	-	28162770	P31FUJ	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.040216289992037135	[239]	[289]	0	hSpCas9	negative selection	10233893
155806419	155806442	7	-	28162770	P31FUJ	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.27086019420492946	[145]	[206]	3	hSpCas9	negative selection	10233894
155806390	155806413	7	+	28162770	P31FUJ	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	0.6249262401583447	[196]	[356]	7	hSpCas9	negative selection	10233895
155806293	155806316	7	+	28162770	P31FUJ	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.6902358137707373	[230]	[437]	7	hSpCas9	negative selection	10233896
155806488	155806511	7	-	28162770	P31FUJ	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-0.8207860571107718	[238]	[158]	-6	hSpCas9	negative selection	10233897
155806374	155806397	7	+	28162770	P31FUJ	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	0.6319704148913983	[189]	[345]	7	hSpCas9	negative selection	10233898
155812068	155812091	7	+	28162770	P31FUJ	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.7588825273736178	[173]	[345]	8	hSpCas9	negative selection	10233899
155811957	155811980	7	+	28162770	P31FUJ	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	-0.19911907815809005	[507]	[519]	-2	hSpCas9	negative selection	10233900
155811840	155811863	7	-	28162770	TF1	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	NaN	[NaN]	[209]	1	hSpCas9	negative selection	10403257
155806449	155806472	7	-	28162770	TF1	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	NaN	[NaN]	[629]	1	hSpCas9	negative selection	10403258
155806430	155806453	7	-	28162770	TF1	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10403259
155806419	155806442	7	-	28162770	TF1	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10403260
155806390	155806413	7	+	28162770	TF1	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10403261
155806293	155806316	7	+	28162770	TF1	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	NaN	[NaN]	[315]	1	hSpCas9	negative selection	10403262
155806488	155806511	7	-	28162770	TF1	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	NaN	[NaN]	[159]	1	hSpCas9	negative selection	10403263
155806374	155806397	7	+	28162770	TF1	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10403264
155812068	155812091	7	+	28162770	TF1	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10403265
155811957	155811980	7	+	28162770	TF1	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	NaN	[NaN]	[486]	1	hSpCas9	negative selection	10403266
155811840	155811863	7	-	28162770	SKM1	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	-0.7327343599249181	[46]	[49]	-5	hSpCas9	negative selection	10572623
155806449	155806472	7	-	28162770	SKM1	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	0.29428533981823346	[136]	[296]	3	hSpCas9	negative selection	10572624
155806430	155806453	7	-	28162770	SKM1	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.2876227931524928	[56]	[122]	3	hSpCas9	negative selection	10572625
155806419	155806442	7	-	28162770	SKM1	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.7418991871713211	[22]	[67]	7	hSpCas9	negative selection	10572626
155806390	155806413	7	+	28162770	SKM1	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	0.3427430643146266	[61]	[138]	3	hSpCas9	negative selection	10572627
155806293	155806316	7	+	28162770	SKM1	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.7216200073182513	[58]	[171]	7	hSpCas9	negative selection	10572628
155806488	155806511	7	-	28162770	SKM1	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-0.1179865256570862	[61]	[100]	-1	hSpCas9	negative selection	10572629
155806374	155806397	7	+	28162770	SKM1	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	0.7034597909504888	[32]	[94]	6	hSpCas9	negative selection	10572630
155812068	155812091	7	+	28162770	SKM1	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.3479233034203068	[55]	[125]	3	hSpCas9	negative selection	10572631
155811957	155811980	7	+	28162770	SKM1	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	0.5380873918589477	[96]	[248]	5	hSpCas9	negative selection	10572632
155811840	155811863	7	-	28162770	SKM1	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	-0.7327343599249181	[46]	[49]	-5	hSpCas9	negative selection	10741989
155806449	155806472	7	-	28162770	SKM1	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	0.29428533981823346	[136]	[296]	3	hSpCas9	negative selection	10741990
155806430	155806453	7	-	28162770	SKM1	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.2876227931524928	[56]	[122]	3	hSpCas9	negative selection	10741991
155806419	155806442	7	-	28162770	SKM1	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.7418991871713211	[22]	[67]	7	hSpCas9	negative selection	10741992
155806390	155806413	7	+	28162770	SKM1	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	0.3427430643146266	[61]	[138]	3	hSpCas9	negative selection	10741993
155806293	155806316	7	+	28162770	SKM1	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.7216200073182513	[58]	[171]	7	hSpCas9	negative selection	10741994
155806488	155806511	7	-	28162770	SKM1	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-0.1179865256570862	[61]	[100]	-1	hSpCas9	negative selection	10741995
155806374	155806397	7	+	28162770	SKM1	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	0.7034597909504888	[32]	[94]	6	hSpCas9	negative selection	10741996
155812068	155812091	7	+	28162770	SKM1	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.3479233034203068	[55]	[125]	3	hSpCas9	negative selection	10741997
155811957	155811980	7	+	28162770	SKM1	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	0.5380873918589477	[96]	[248]	5	hSpCas9	negative selection	10741998
155811840	155811863	7	-	28162770	PL21	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	0.885043553084383	[157]	[126]	7	hSpCas9	negative selection	10911355
155806449	155806472	7	-	28162770	PL21	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	0.0458114680980265	[344]	[154]	0	hSpCas9	negative selection	10911356
155806430	155806453	7	-	28162770	PL21	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	-0.164134771107637	[241]	[93]	-1	hSpCas9	negative selection	10911357
155806419	155806442	7	-	28162770	PL21	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.2762984294536669	[127]	[45]	-2	hSpCas9	negative selection	10911358
155806390	155806413	7	+	28162770	PL21	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	-0.5129792377225182	[199]	[60]	-4	hSpCas9	negative selection	10911359
155806293	155806316	7	+	28162770	PL21	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.23116651010994474	[183]	[93]	2	hSpCas9	negative selection	10911360
155806488	155806511	7	-	28162770	PL21	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-2.226125140212778	[257]	[23]	-8	hSpCas9	negative selection	10911361
155806374	155806397	7	+	28162770	PL21	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	-0.16598828430857737	[115]	[44]	-1	hSpCas9	negative selection	10911362
155812068	155812091	7	+	28162770	PL21	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.7851021152104762	[127]	[95]	6	hSpCas9	negative selection	10911363
155811957	155811980	7	+	28162770	PL21	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	0.48627938058590614	[350]	[213]	4	hSpCas9	negative selection	10911364
155811840	155811863	7	-	28162770	P31FUJ	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	0.8741129995021334	[116]	[251]	8	hSpCas9	negative selection	11080721
155806449	155806472	7	-	28162770	P31FUJ	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	0.09687539007791868	[556]	[699]	1	hSpCas9	negative selection	11080722
155806430	155806453	7	-	28162770	P31FUJ	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.040216289992037135	[239]	[289]	0	hSpCas9	negative selection	11080723
155806419	155806442	7	-	28162770	P31FUJ	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.27086019420492946	[145]	[206]	3	hSpCas9	negative selection	11080724
155806390	155806413	7	+	28162770	P31FUJ	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	0.6249262401583447	[196]	[356]	7	hSpCas9	negative selection	11080725
155806293	155806316	7	+	28162770	P31FUJ	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.6902358137707373	[230]	[437]	7	hSpCas9	negative selection	11080726
155806488	155806511	7	-	28162770	P31FUJ	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-0.8207860571107718	[238]	[158]	-6	hSpCas9	negative selection	11080727
155806374	155806397	7	+	28162770	P31FUJ	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	0.6319704148913983	[189]	[345]	7	hSpCas9	negative selection	11080728
155812068	155812091	7	+	28162770	P31FUJ	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.7588825273736178	[173]	[345]	8	hSpCas9	negative selection	11080729
155811957	155811980	7	+	28162770	P31FUJ	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	-0.19911907815809005	[507]	[519]	-2	hSpCas9	negative selection	11080730
155811840	155811863	7	-	28162770	OCIAML5	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	-0.22316072255524388	[96]	[149]	-2	hSpCas9	negative selection	11250087
155806449	155806472	7	-	28162770	OCIAML5	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	0.8729438899648558	[205]	[680]	7	hSpCas9	negative selection	11250088
155806430	155806453	7	-	28162770	OCIAML5	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	-0.43291296311292127	[174]	[233]	-3	hSpCas9	negative selection	11250089
155806419	155806442	7	-	28162770	OCIAML5	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.6275063128448388	[94]	[110]	-4	hSpCas9	negative selection	11250090
155806390	155806413	7	+	28162770	OCIAML5	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	-0.6341615405198628	[91]	[106]	-4	hSpCas9	negative selection	11250091
155806293	155806316	7	+	28162770	OCIAML5	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.8450062961786965	[98]	[320]	7	hSpCas9	negative selection	11250092
155806488	155806511	7	-	28162770	OCIAML5	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-1.5644899807674115	[135]	[82]	-7	hSpCas9	negative selection	11250093
155806374	155806397	7	+	28162770	OCIAML5	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	-0.03263881650581785	[84]	[149]	0	hSpCas9	negative selection	11250094
155812068	155812091	7	+	28162770	OCIAML5	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.6333602563062447	[124]	[349]	5	hSpCas9	negative selection	11250095
155811957	155811980	7	+	28162770	OCIAML5	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	0.22504235483376922	[254]	[537]	1	hSpCas9	negative selection	11250096
155811840	155811863	7	-	28162770	EOL1	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	0.11867634068826116	[242]	[138]	1	hSpCas9	negative selection	11419453
155806449	155806472	7	-	28162770	EOL1	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	-0.117434677904241	[522]	[253]	-1	hSpCas9	negative selection	11419454
155806430	155806453	7	-	28162770	EOL1	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.8628381993715504	[405]	[388]	7	hSpCas9	negative selection	11419455
155806419	155806442	7	-	28162770	EOL1	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-1.0581742369976297	[248]	[62]	-6	hSpCas9	negative selection	11419456
155806390	155806413	7	+	28162770	EOL1	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	0.9178375499809819	[430]	[428]	7	hSpCas9	negative selection	11419457
155806293	155806316	7	+	28162770	EOL1	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.8830973280770313	[458]	[445]	7	hSpCas9	negative selection	11419458
155806488	155806511	7	-	28162770	EOL1	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-0.5054400691742809	[290]	[107]	-4	hSpCas9	negative selection	11419459
155806374	155806397	7	+	28162770	EOL1	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	-1.0754522284294652	[143]	[35]	-6	hSpCas9	negative selection	11419460
155812068	155812091	7	+	28162770	EOL1	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.32102943718671295	[229]	[96]	-2	hSpCas9	negative selection	11419461
155811957	155811980	7	+	28162770	EOL1	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	0.6929220704560493	[417]	[355]	6	hSpCas9	negative selection	11419462
155811840	155811863	7	-	28162770	MOLM13	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	0.19711932693117967	[186]	[154]	1	hSpCas9	negative selection	11588819
155806449	155806472	7	-	28162770	MOLM13	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	0.168329099685671	[623]	[506]	1	hSpCas9	negative selection	11588820
155806430	155806453	7	-	28162770	MOLM13	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.6549749341450741	[324]	[369]	5	hSpCas9	negative selection	11588821
155806419	155806442	7	-	28162770	MOLM13	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	1.0646773176625244	[161]	[244]	7	hSpCas9	negative selection	11588822
155806390	155806413	7	+	28162770	MOLM13	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	0.7583096751734516	[286]	[350]	6	hSpCas9	negative selection	11588823
155806293	155806316	7	+	28162770	MOLM13	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.9331611833435591	[380]	[525]	7	hSpCas9	negative selection	11588824
155806488	155806511	7	-	28162770	MOLM13	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-1.4509738557300158	[362]	[95]	-6	hSpCas9	negative selection	11588825
155806374	155806397	7	+	28162770	MOLM13	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	0.5622167640927318	[147]	[157]	4	hSpCas9	negative selection	11588826
155812068	155812091	7	+	28162770	MOLM13	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.05285188226573498	[227]	[170]	0	hSpCas9	negative selection	11588827
155811957	155811980	7	+	28162770	MOLM13	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	-0.07590393020017316	[569]	[390]	0	hSpCas9	negative selection	11588828
155811840	155811863	7	-	28162770	HEL	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	0.7630330657180687	[183]	[199]	6	hSpCas9	negative selection	11758185
155806449	155806472	7	-	28162770	HEL	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	0.8474292516033461	[491]	[566]	7	hSpCas9	negative selection	11758186
155806430	155806453	7	-	28162770	HEL	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.5901119013491471	[334]	[322]	5	hSpCas9	negative selection	11758187
155806419	155806442	7	-	28162770	HEL	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.77576425063114	[175]	[192]	6	hSpCas9	negative selection	11758188
155806390	155806413	7	+	28162770	HEL	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	0.1191768759433442	[298]	[207]	1	hSpCas9	negative selection	11758189
155806293	155806316	7	+	28162770	HEL	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	1.3839570306927205	[270]	[452]	9	hSpCas9	negative selection	11758190
155806488	155806511	7	-	28162770	HEL	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-0.1274385411877068	[248]	[145]	-1	hSpCas9	negative selection	11758191
155806374	155806397	7	+	28162770	HEL	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	0.46216658635853625	[101]	[89]	4	hSpCas9	negative selection	11758192
155812068	155812091	7	+	28162770	HEL	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.7483490199609556	[157]	[169]	6	hSpCas9	negative selection	11758193
155811957	155811980	7	+	28162770	HEL	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	0.5391826401737597	[461]	[429]	4	hSpCas9	negative selection	11758194
155811840	155811863	7	-	28162770	MV411	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	-0.5548817813775304	[142]	[81]	-4	hSpCas9	negative selection	11927551
155806449	155806472	7	-	28162770	MV411	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	-0.19701267631610753	[478]	[351]	-1	hSpCas9	negative selection	11927552
155806430	155806453	7	-	28162770	MV411	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	-0.9405521664215283	[220]	[96]	-6	hSpCas9	negative selection	11927553
155806419	155806442	7	-	28162770	MV411	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	-0.9058087095129067	[128]	[57]	-6	hSpCas9	negative selection	11927554
155806390	155806413	7	+	28162770	MV411	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	0.3610001096059751	[231]	[250]	3	hSpCas9	negative selection	11927555
155806293	155806316	7	+	28162770	MV411	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.6299071876051885	[167]	[218]	6	hSpCas9	negative selection	11927556
155806488	155806511	7	-	28162770	MV411	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-1.948959662020728	[219]	[47]	-8	hSpCas9	negative selection	11927557
155806374	155806397	7	+	28162770	MV411	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	-1.074490544104587	[99]	[39]	-6	hSpCas9	negative selection	11927558
155812068	155812091	7	+	28162770	MV411	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.8916392548786075	[166]	[260]	7	hSpCas9	negative selection	11927559
155811957	155811980	7	+	28162770	MV411	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	0.5632654461337199	[236]	[294]	5	hSpCas9	negative selection	11927560
155811840	155811863	7	-	28162770	MONOMAC1	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	1.1872283034244737	[76]	[200]	9	hSpCas9	negative selection	12096917
155806449	155806472	7	-	28162770	MONOMAC1	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	1.0413265311886777	[230]	[544]	8	hSpCas9	negative selection	12096918
155806430	155806453	7	-	28162770	MONOMAC1	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.5519013887727285	[143]	[241]	5	hSpCas9	negative selection	12096919
155806419	155806442	7	-	28162770	MONOMAC1	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.4757984096869368	[68]	[109]	5	hSpCas9	negative selection	12096920
155806390	155806413	7	+	28162770	MONOMAC1	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	0.2901504379751254	[116]	[163]	3	hSpCas9	negative selection	12096921
155806293	155806316	7	+	28162770	MONOMAC1	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.5707897108114128	[147]	[251]	5	hSpCas9	negative selection	12096922
155806488	155806511	7	-	28162770	MONOMAC1	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	0.16141712385292273	[116]	[149]	1	hSpCas9	negative selection	12096923
155806374	155806397	7	+	28162770	MONOMAC1	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	-0.44030799807191756	[57]	[48]	-4	hSpCas9	negative selection	12096924
155812068	155812091	7	+	28162770	MONOMAC1	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	-0.10561381929595895	[106]	[113]	-1	hSpCas9	negative selection	12096925
155811957	155811980	7	+	28162770	MONOMAC1	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	-0.35946731195494175	[215]	[192]	-3	hSpCas9	negative selection	12096926
155811840	155811863	7	-	28162770	OCIAML2	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	-0.06750564750681787	[37]	[200]	0	hSpCas9	negative selection	12266283
155806449	155806472	7	-	28162770	OCIAML2	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	-0.07208044875188646	[76]	[405]	0	hSpCas9	negative selection	12266284
155806430	155806453	7	-	28162770	OCIAML2	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	-0.05559232596331748	[44]	[239]	0	hSpCas9	negative selection	12266285
155806419	155806442	7	-	28162770	OCIAML2	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	0.3773670813127889	[19]	[143]	3	hSpCas9	negative selection	12266286
155806390	155806413	7	+	28162770	OCIAML2	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	-0.1805271762101967	[54]	[268]	-1	hSpCas9	negative selection	12266287
155806293	155806316	7	+	28162770	OCIAML2	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	1.0811658115437957	[32]	[386]	8	hSpCas9	negative selection	12266288
155806488	155806511	7	-	28162770	OCIAML2	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-0.9455387804984039	[40]	[117]	-6	hSpCas9	negative selection	12266289
155806374	155806397	7	+	28162770	OCIAML2	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	-0.7252026523277588	[16]	[56]	-5	hSpCas9	negative selection	12266290
155812068	155812091	7	+	28162770	OCIAML2	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	0.24984764613547605	[21]	[144]	2	hSpCas9	negative selection	12266291
155811957	155811980	7	+	28162770	OCIAML2	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	-0.05426692849674997	[67]	[362]	0	hSpCas9	negative selection	12266292
155811840	155811863	7	-	28162770	OCIAML3	viability	GGATGAAGAAAACACCGGAGCGG	SHH	ENSG00000164690	-2.2087174844393713	[48]	[31]	-8	hSpCas9	negative selection	12435649
155806449	155806472	7	-	28162770	OCIAML3	viability	CGAAGATGGCCACCACTCAGAGG	SHH	ENSG00000164690	-0.08180148203832127	[121]	[347]	0	hSpCas9	negative selection	12435650
155806430	155806453	7	-	28162770	OCIAML3	viability	GAGGAGTCTCTGCACTACGAGGG	SHH	ENSG00000164690	0.20380350906257017	[64]	[225]	2	hSpCas9	negative selection	12435651
155806419	155806442	7	-	28162770	OCIAML3	viability	GCACTACGAGGGCCGCGCAGTGG	SHH	ENSG00000164690	1.798309782454597	[13]	[146]	9	hSpCas9	negative selection	12435652
155806390	155806413	7	+	28162770	OCIAML3	viability	GCTGCGGTCGCGGTCAGACGTGG	SHH	ENSG00000164690	0.40051722960968583	[65]	[262]	4	hSpCas9	negative selection	12435653
155806293	155806316	7	+	28162770	OCIAML3	viability	TACCTGCTTTCACCGAGCAGTGG	SHH	ENSG00000164690	0.18667933127136105	[77]	[267]	1	hSpCas9	negative selection	12435654
155806488	155806511	7	-	28162770	OCIAML3	viability	GTGGCCAGGAGTGAAACTGCGGG	SHH	ENSG00000164690	-0.4071295056006537	[46]	[106]	-3	hSpCas9	negative selection	12435655
155806374	155806397	7	+	28162770	OCIAML3	viability	CCAGCATGCCGTACTTGCTGCGG	SHH	ENSG00000164690	-0.4420045468791133	[26]	[59]	-3	hSpCas9	negative selection	12435656
155812068	155812091	7	+	28162770	OCIAML3	viability	ATACCAGCAGCGAGGAGACGAGG	SHH	ENSG00000164690	1	[52]	[319]	8	hSpCas9	negative selection	12435657
155811957	155811980	7	+	28162770	OCIAML3	viability	GGGTCTTCTCGGCCACATTGGGG	SHH	ENSG00000164690	-0.19028545427315358	[95]	[253]	-1	hSpCas9	negative selection	12435658