Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:59307
• Symbol:SIGIRR
• Description:single Ig and TIR domain containing

DataSource: http://genomecrispr.dkfz.de/#!/results/SIGIRR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
408759	408782	11	+	26472758	Jiyoye	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-3.3565902720040484	[325]	[23]	-9	hSpCas9	negative selection	146738
406433	406456	11	-	26472758	Jiyoye	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.4357445337026443	[99]	[101]	3	hSpCas9	negative selection	146739
408101	408124	11	+	26472758	Jiyoye	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	1.8608933489487773	[22]	[62]	8	hSpCas9	negative selection	146740
407901	407924	11	+	26472758	Jiyoye	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-1.5714509677015598	[66]	[16]	-7	hSpCas9	negative selection	146741
407829	407852	11	-	26472758	Jiyoye	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.8913749052921129	[167]	[234]	6	hSpCas9	negative selection	146742
407528	407551	11	+	26472758	Jiyoye	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	0.6506294183701511	[271]	[321]	5	hSpCas9	negative selection	146743
407139	407162	11	+	26472758	Jiyoye	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	-0.353154205725843	[82]	[48]	-3	hSpCas9	negative selection	146744
407051	407074	11	+	26472758	Jiyoye	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	1.3875465747569409	[36]	[72]	8	hSpCas9	negative selection	146745
406863	406886	11	+	26472758	Jiyoye	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	-0.08381097100626889	[207]	[147]	0	hSpCas9	negative selection	146746
407872	407895	11	+	26472758	Jiyoye	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	-0.08467771482380149	[89]	[63]	0	hSpCas9	negative selection	146747
408759	408782	11	+	26472758	KBM7	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-1.195997090825402	[952,827]	[260,111]	-7	hSpCas9	negative selection	337856
406433	406456	11	-	26472758	KBM7	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.9469195798874208	[670,587]	[625,518]	9	hSpCas9	negative selection	337857
408101	408124	11	+	26472758	KBM7	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.16106706289323813	[285,158]	[224,14]	1	hSpCas9	negative selection	337858
407901	407924	11	+	26472758	KBM7	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-0.5378632568799102	[225,94]	[29,67]	-5	hSpCas9	negative selection	337859
407829	407852	11	-	26472758	KBM7	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	-0.10806172803203506	[1099,793]	[458,362]	-1	hSpCas9	negative selection	337860
407528	407551	11	+	26472758	KBM7	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	-0.050169688188296035	[1248,992]	[550,464]	0	hSpCas9	negative selection	337861
407139	407162	11	+	26472758	KBM7	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	-0.3355052385663274	[465,396]	[145,172]	-3	hSpCas9	negative selection	337862
407051	407074	11	+	26472758	KBM7	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	0.2992046835000818	[603,298]	[206,294]	3	hSpCas9	negative selection	337863
406863	406886	11	+	26472758	KBM7	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	-0.13275539591201546	[927,864]	[517,265]	-1	hSpCas9	negative selection	337864
407872	407895	11	+	26472758	KBM7	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.1530436712161629	[254,309]	[170,130]	1	hSpCas9	negative selection	337865
408759	408782	11	+	26472758	Raji	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-2.287679264143978	[525]	[24]	-9	hSpCas9	negative selection	528974
406433	406456	11	-	26472758	Raji	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	-0.06664586440144943	[175]	[38]	0	hSpCas9	negative selection	528975
408101	408124	11	+	26472758	Raji	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.17449773123213674	[41]	[10]	1	hSpCas9	negative selection	528976
407901	407924	11	+	26472758	Raji	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-2.0890136774299037	[109]	[5]	-8	hSpCas9	negative selection	528977
407829	407852	11	-	26472758	Raji	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	-0.3030812341154202	[419]	[78]	-3	hSpCas9	negative selection	528978
407528	407551	11	+	26472758	Raji	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	0.4437090586384026	[338]	[106]	4	hSpCas9	negative selection	528979
407139	407162	11	+	26472758	Raji	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	0.5637618300333428	[171]	[58]	5	hSpCas9	negative selection	528980
407051	407074	11	+	26472758	Raji	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	0.5916836970895569	[182]	[63]	5	hSpCas9	negative selection	528981
406863	406886	11	+	26472758	Raji	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	-0.11197482587321539	[474]	[101]	-1	hSpCas9	negative selection	528982
407872	407895	11	+	26472758	Raji	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.048489846320030866	[199]	[47]	0	hSpCas9	negative selection	528983
408759	408782	11	+	26472758	K562	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-2.8351016119770795	[633]	[74]	-8	hSpCas9	negative selection	720092
406433	406456	11	-	26472758	K562	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	1.0065225686291503	[420]	[713]	8	hSpCas9	negative selection	720093
408101	408124	11	+	26472758	K562	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.8523728710138321	[165]	[252]	7	hSpCas9	negative selection	720094
407901	407924	11	+	26472758	K562	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-0.11106192693194217	[86]	[67]	-1	hSpCas9	negative selection	720095
407829	407852	11	-	26472758	K562	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.1738140560861816	[669]	[637]	1	hSpCas9	negative selection	720096
407528	407551	11	+	26472758	K562	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	0.5094723011368929	[832]	[1000]	4	hSpCas9	negative selection	720097
407139	407162	11	+	26472758	K562	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	1.5303275997528274	[218]	[533]	9	hSpCas9	negative selection	720098
407051	407074	11	+	26472758	K562	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	0.4847330570001571	[319]	[377]	4	hSpCas9	negative selection	720099
406863	406886	11	+	26472758	K562	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	-0.7571692692367452	[908]	[453]	-4	hSpCas9	negative selection	720100
407872	407895	11	+	26472758	K562	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	1.2293905184341154	[192]	[381]	9	hSpCas9	negative selection	720101
406857	406880	11	+	26627737	DLD1	viability	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.39352323254428756	[234]	[71,164,60]	4	hSpCas9	negative selection	778447
407061	407084	11	+	26627737	DLD1	viability	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	0.7165095220231235	[494]	[195,387,193]	7	hSpCas9	negative selection	778448
407482	407505	11	-	26627737	DLD1	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.7074515716881353	[265]	[148,111,143]	7	hSpCas9	negative selection	778449
407940	407963	11	-	26627737	DLD1	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.5512662869632239	[1433]	[878,835,315]	5	hSpCas9	negative selection	778451
408101	408124	11	+	26627737	DLD1	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.3653285778505764	[278]	[110,118,107]	4	hSpCas9	negative selection	778453
408841	408864	11	+	26627737	DLD1	viability	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.3531940354288583	[3944]	[1397,820,709]	-4	hSpCas9	negative selection	778454
406857	406880	11	+	26627737	GBM cells	viability after 5 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	-0.08581936846100424	[93]	[55,38]	-1	hSpCas9	negative selection	860762
407061	407084	11	+	26627737	GBM cells	viability after 5 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.4194476049814844	[403]	[166,156]	-6	hSpCas9	negative selection	860763
407482	407505	11	-	26627737	GBM cells	viability after 5 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.1663037845607952	[180]	[70,101]	-3	hSpCas9	negative selection	860764
407940	407963	11	-	26627737	GBM cells	viability after 5 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.11279278726730047	[606]	[433,269]	1	hSpCas9	negative selection	860766
408101	408124	11	+	26627737	GBM cells	viability after 5 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.5717491316321763	[137]	[111,107]	8	hSpCas9	negative selection	860768
408841	408864	11	+	26627737	GBM cells	viability after 5 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.2260013916390613	[1916]	[903,853]	-4	hSpCas9	negative selection	860769
406857	406880	11	+	26627737	GBM cells	viability after 13 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.46042975834569855	[93]	[78,62]	6	hSpCas9	negative selection	943077
407061	407084	11	+	26627737	GBM cells	viability after 13 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.6731291816408614	[403]	[110,158]	-7	hSpCas9	negative selection	943078
407482	407505	11	-	26627737	GBM cells	viability after 13 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.4687428833812025	[180]	[65,74]	-5	hSpCas9	negative selection	943079
407940	407963	11	-	26627737	GBM cells	viability after 13 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.29984689358275585	[606]	[507,321]	4	hSpCas9	negative selection	943081
408101	408124	11	+	26627737	GBM cells	viability after 13 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.5030994488053201	[137]	[136,80]	6	hSpCas9	negative selection	943083
408841	408864	11	+	26627737	GBM cells	viability after 13 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.18109433696745025	[1916]	[1078,785]	-2	hSpCas9	negative selection	943084
406857	406880	11	+	26627737	GBM cells	viability after 21 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.39531797574483196	[93]	[74,59]	4	hSpCas9	negative selection	1025392
407061	407084	11	+	26627737	GBM cells	viability after 21 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.47663442040486664	[403]	[163,151]	-4	hSpCas9	negative selection	1025393
407482	407505	11	-	26627737	GBM cells	viability after 21 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.10118268401903069	[180]	[105,104]	1	hSpCas9	negative selection	1025394
407940	407963	11	-	26627737	GBM cells	viability after 21 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.252821342875458	[606]	[370,412]	2	hSpCas9	negative selection	1025396
408101	408124	11	+	26627737	GBM cells	viability after 21 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.7227992423565432	[137]	[129,117]	7	hSpCas9	negative selection	1025398
408841	408864	11	+	26627737	GBM cells	viability after 21 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.23186405921634723	[1916]	[913,861]	-2	hSpCas9	negative selection	1025399
406857	406880	11	+	26627737	RPE1	viability after 9 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.3076419136947277	[179]	[67,71]	2	hSpCas9	negative selection	1107707
407061	407084	11	+	26627737	RPE1	viability after 9 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	0.18623040751459352	[842]	[315,279]	1	hSpCas9	negative selection	1107708
407482	407505	11	-	26627737	RPE1	viability after 9 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-1.249609784316658	[447]	[51,67]	-7	hSpCas9	negative selection	1107709
407940	407963	11	-	26627737	RPE1	viability after 9 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.14121722954410698	[2640]	[702,809]	-1	hSpCas9	negative selection	1107711
408101	408124	11	+	26627737	RPE1	viability after 9 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.5947918077906107	[616]	[140,110]	-4	hSpCas9	negative selection	1107713
408841	408864	11	+	26627737	RPE1	viability after 9 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.3475300951275595	[6058]	[1492,1487]	-2	hSpCas9	negative selection	1107714
406857	406880	11	+	26627737	RPE1	viability after 12 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.532952356962475	[179]	[85,52]	3	hSpCas9	negative selection	1190022
407061	407084	11	+	26627737	RPE1	viability after 12 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	0.7966805128084156	[842]	[407,377]	5	hSpCas9	negative selection	1190023
407482	407505	11	-	26627737	RPE1	viability after 12 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.4452690458803972	[447]	[152,19]	-3	hSpCas9	negative selection	1190024
407940	407963	11	-	26627737	RPE1	viability after 12 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.22033824488476084	[2640]	[660,1001]	1	hSpCas9	negative selection	1190026
408101	408124	11	+	26627737	RPE1	viability after 12 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.7038264833196277	[616]	[144,55]	-5	hSpCas9	negative selection	1190028
408841	408864	11	+	26627737	RPE1	viability after 12 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.0545422962441342	[6058]	[1752,1370]	0	hSpCas9	negative selection	1190029
406857	406880	11	+	26627737	RPE1	viability after 15 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.6223527539384188	[179]	[84,71]	4	hSpCas9	negative selection	1272337
407061	407084	11	+	26627737	RPE1	viability after 15 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.022985385622435683	[842]	[307,163]	0	hSpCas9	negative selection	1272338
407482	407505	11	-	26627737	RPE1	viability after 15 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.11381925353310696	[447]	[194,41]	0	hSpCas9	negative selection	1272339
407940	407963	11	-	26627737	RPE1	viability after 15 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.06147391749774167	[2640]	[1026,540]	0	hSpCas9	negative selection	1272341
408101	408124	11	+	26627737	RPE1	viability after 15 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.17409905721431124	[616]	[199,110]	-1	hSpCas9	negative selection	1272343
408841	408864	11	+	26627737	RPE1	viability after 15 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.23108303623093374	[6058]	[1359,1556]	-1	hSpCas9	negative selection	1272344
406857	406880	11	+	26627737	RPE1	viability after 18 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	-0.2007795406222126	[179]	[49,33]	-1	hSpCas9	negative selection	1354652
407061	407084	11	+	26627737	RPE1	viability after 18 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.1383822176001871	[842]	[255,153]	-1	hSpCas9	negative selection	1354653
407482	407505	11	-	26627737	RPE1	viability after 18 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.26605679762588363	[447]	[159,36]	-2	hSpCas9	negative selection	1354654
407940	407963	11	-	26627737	RPE1	viability after 18 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.05577872684036045	[2640]	[822,652]	0	hSpCas9	negative selection	1354656
408101	408124	11	+	26627737	RPE1	viability after 18 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.2555086655227066	[616]	[138,139]	-2	hSpCas9	negative selection	1354658
408841	408864	11	+	26627737	RPE1	viability after 18 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	0.1358098402211172	[6058]	[1345,2277]	0	hSpCas9	negative selection	1354659
406857	406880	11	+	26627737	HeLa	viability after 8 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	-0.6185104037308825	[255]	[80,72,65]	-6	hSpCas9	negative selection	1436967
407061	407084	11	+	26627737	HeLa	viability after 8 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	1.0690704423378028	[375]	[488,349,230]	7	hSpCas9	negative selection	1436968
407482	407505	11	-	26627737	HeLa	viability after 8 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.7713944439387691	[281]	[94,101,26]	-6	hSpCas9	negative selection	1436969
407940	407963	11	-	26627737	HeLa	viability after 8 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.18843156733326127	[1279]	[809,458,670]	1	hSpCas9	negative selection	1436971
408101	408124	11	+	26627737	HeLa	viability after 8 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.500444574300638	[240]	[163,113,168]	4	hSpCas9	negative selection	1436973
408841	408864	11	+	26627737	HeLa	viability after 8 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.18528712474334563	[2941]	[1280,1141,997]	-2	hSpCas9	negative selection	1436974
406857	406880	11	+	26627737	HeLa	viability after 12 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.3750020882204109	[255]	[274,57,90]	3	hSpCas9	negative selection	1519282
407061	407084	11	+	26627737	HeLa	viability after 12 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	0.8721818033338563	[375]	[321,202,337]	6	hSpCas9	negative selection	1519283
407482	407505	11	-	26627737	HeLa	viability after 12 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.0001660040769644322	[281]	[16,170,152]	0	hSpCas9	negative selection	1519284
407940	407963	11	-	26627737	HeLa	viability after 12 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.06496463287971732	[1279]	[381,528,599]	0	hSpCas9	negative selection	1519286
408101	408124	11	+	26627737	HeLa	viability after 12 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.45147697693630257	[240]	[82,211,103]	4	hSpCas9	negative selection	1519288
408841	408864	11	+	26627737	HeLa	viability after 12 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.1274153913453957	[2941]	[1068,1177,1083]	-1	hSpCas9	negative selection	1519289
406857	406880	11	+	26627737	HeLa	viability after 15 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	-1.3959441964150971	[255]	[37,14,67]	-8	hSpCas9	negative selection	1601597
407061	407084	11	+	26627737	HeLa	viability after 15 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.1496028938718184	[375]	[140,97,177]	-1	hSpCas9	negative selection	1601598
407482	407505	11	-	26627737	HeLa	viability after 15 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.1455820256395859	[281]	[112,130,137]	1	hSpCas9	negative selection	1601599
407940	407963	11	-	26627737	HeLa	viability after 15 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.5795116532640197	[1279]	[900,539,902]	5	hSpCas9	negative selection	1601601
408101	408124	11	+	26627737	HeLa	viability after 15 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.910995210140521	[240]	[186,186,178]	7	hSpCas9	negative selection	1601603
408841	408864	11	+	26627737	HeLa	viability after 15 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	0.00749792836577301	[2941]	[1164,1524,898]	0	hSpCas9	negative selection	1601604
406857	406880	11	+	26627737	HeLa	viability after 18 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	-1.3022839106115516	[255]	[30,11,67]	-8	hSpCas9	negative selection	1683912
407061	407084	11	+	26627737	HeLa	viability after 18 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.17193874581041052	[375]	[92,77,177]	-1	hSpCas9	negative selection	1683913
407482	407505	11	-	26627737	HeLa	viability after 18 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.15491727562886187	[281]	[76,108,137]	1	hSpCas9	negative selection	1683914
407940	407963	11	-	26627737	HeLa	viability after 18 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.5670289518701186	[1279]	[593,443,902]	4	hSpCas9	negative selection	1683916
408101	408124	11	+	26627737	HeLa	viability after 18 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.9007327556605217	[240]	[121,155,178]	6	hSpCas9	negative selection	1683918
408841	408864	11	+	26627737	HeLa	viability after 18 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	0.020213380458038	[2941]	[790,1276,898]	0	hSpCas9	negative selection	1683919
406857	406880	11	+	26627737	HCT116	viability after 6 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.7569588521831631	[231]	[118,29]	4	hSpCas9	negative selection	1766227
407061	407084	11	+	26627737	HCT116	viability after 6 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	0.16766809877325484	[857]	[175,137]	0	hSpCas9	negative selection	1766228
407482	407505	11	-	26627737	HCT116	viability after 6 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.08907967115767601	[373]	[155,10]	0	hSpCas9	negative selection	1766229
407940	407963	11	-	26627737	HCT116	viability after 6 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.6932444073591559	[2088]	[501,546]	4	hSpCas9	negative selection	1766231
408101	408124	11	+	26627737	HCT116	viability after 6 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.6594006857410197	[301]	[25,101]	3	hSpCas9	negative selection	1766233
408841	408864	11	+	26627737	HCT116	viability after 6 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	0.3427893479336519	[4737]	[816,1014]	2	hSpCas9	negative selection	1766234
406857	406880	11	+	26627737	HCT116	viability after 8 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	-0.15984268131045676	[147]	[55,114,47]	-2	hSpCas9	negative selection	1848542
407061	407084	11	+	26627737	HCT116	viability after 8 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	1.051549928176236	[156]	[194,144,197]	8	hSpCas9	negative selection	1848543
407482	407505	11	-	26627737	HCT116	viability after 8 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.10580950437847769	[173]	[94,79,133]	1	hSpCas9	negative selection	1848544
407940	407963	11	-	26627737	HCT116	viability after 8 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.1693899518722053	[884]	[638,388,617]	2	hSpCas9	negative selection	1848546
408101	408124	11	+	26627737	HCT116	viability after 8 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.6202287627340878	[307]	[109,91,128]	-6	hSpCas9	negative selection	1848548
408841	408864	11	+	26627737	HCT116	viability after 8 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.49117536939789863	[2573]	[1045,982,998]	-5	hSpCas9	negative selection	1848549
406857	406880	11	+	26627737	HCT116	viability after 9 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.5387174914091579	[231]	[194,6]	4	hSpCas9	negative selection	1930857
407061	407084	11	+	26627737	HCT116	viability after 9 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	0.34900095518636587	[857]	[245,327]	2	hSpCas9	negative selection	1930858
407482	407505	11	-	26627737	HCT116	viability after 9 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	1.5351332270677833	[373]	[313,269]	8	hSpCas9	negative selection	1930859
407940	407963	11	-	26627737	HCT116	viability after 9 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.14720410754712132	[2088]	[849,229]	-1	hSpCas9	negative selection	1930861
408101	408124	11	+	26627737	HCT116	viability after 9 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.22847387139860498	[301]	[79,59]	-1	hSpCas9	negative selection	1930863
408841	408864	11	+	26627737	HCT116	viability after 9 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	0.04614513747916371	[4737]	[1527,1130]	0	hSpCas9	negative selection	1930864
406857	406880	11	+	26627737	HCT116	viability after 12 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	-0.06279769684225722	[147]	[65,109,48]	0	hSpCas9	negative selection	2013172
407061	407084	11	+	26627737	HCT116	viability after 12 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	1.2272013894920288	[156]	[239,177,156]	8	hSpCas9	negative selection	2013173
407482	407505	11	-	26627737	HCT116	viability after 12 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.04839313247647603	[173]	[90,135,57]	0	hSpCas9	negative selection	2013174
407940	407963	11	-	26627737	HCT116	viability after 12 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.06653334760549856	[884]	[612,401,432]	0	hSpCas9	negative selection	2013176
408101	408124	11	+	26627737	HCT116	viability after 12 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-1.298842703774485	[307]	[74,83,37]	-8	hSpCas9	negative selection	2013178
408841	408864	11	+	26627737	HCT116	viability after 12 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.5861537986792991	[2573]	[867,938,899]	-6	hSpCas9	negative selection	2013179
406857	406880	11	+	26627737	HCT116	viability after 15 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.2953834509991383	[147]	[51,103,149]	3	hSpCas9	negative selection	2095487
407061	407084	11	+	26627737	HCT116	viability after 15 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	1.1424944288020407	[156]	[272,204,128]	8	hSpCas9	negative selection	2095488
407482	407505	11	-	26627737	HCT116	viability after 15 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.11713296762110037	[173]	[41,110,116]	-1	hSpCas9	negative selection	2095489
407940	407963	11	-	26627737	HCT116	viability after 15 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.5194455275181289	[884]	[791,563,835]	5	hSpCas9	negative selection	2095491
408101	408124	11	+	26627737	HCT116	viability after 15 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.8657624110932538	[307]	[74,73,138]	-7	hSpCas9	negative selection	2095493
408841	408864	11	+	26627737	HCT116	viability after 15 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.5563749116406629	[2573]	[1067,843,1109]	-5	hSpCas9	negative selection	2095494
406857	406880	11	+	26627737	HCT116	viability after 18 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	1.0872710565031922	[147]	[44,247,156]	8	hSpCas9	negative selection	2177802
407061	407084	11	+	26627737	HCT116	viability after 18 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	0.7356691663308916	[156]	[155,89,135]	6	hSpCas9	negative selection	2177803
407482	407505	11	-	26627737	HCT116	viability after 18 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.49736202425053366	[173]	[34,101,37]	-4	hSpCas9	negative selection	2177804
407940	407963	11	-	26627737	HCT116	viability after 18 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.24685366298333733	[884]	[402,542,577]	2	hSpCas9	negative selection	2177806
408101	408124	11	+	26627737	HCT116	viability after 18 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.9603797030476486	[307]	[46,84,97]	-7	hSpCas9	negative selection	2177808
408841	408864	11	+	26627737	HCT116	viability after 18 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.9445531649873793	[2573]	[690,531,727]	-7	hSpCas9	negative selection	2177809
415175	415198	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAAAGTGCCGTGCCTGGGTGGG	SIGIRR	ENSG00000185187	3.0642779772508777	[57,31]	[155,3]	8	dCas9-VP64	positive selection	2399239
415118	415141	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGAGCTACAGGAAGAGCCGGG	SIGIRR	ENSG00000185187	2.0714594613366035	[5,39]	[26,15]	7	dCas9-VP64	positive selection	2399240
415152	415175	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGGGGCGGGCTCCAGAGGAAGG	SIGIRR	ENSG00000185187	-1.4457999515129916	[11,87]	[2,3]	-8	dCas9-VP64	positive selection	2399241
415175	415198	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAAAGTGCCGTGCCTGGGTGGG	SIGIRR	ENSG00000185187	0.7570661822329459	[45,3]	[13,13]	5	dCas9-VP64	positive selection	2494494
415118	415141	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGAGCTACAGGAAGAGCCGGG	SIGIRR	ENSG00000185187	2.1902439492887003	[50,43]	[56,83]	8	dCas9-VP64	positive selection	2494495
415152	415175	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGGGGCGGGCTCCAGAGGAAGG	SIGIRR	ENSG00000185187	1.5330068206615486	[49,86]	[98,32]	8	dCas9-VP64	positive selection	2494496
407873	407896	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.19150721786151703	[3,3]	[3,3]	4	hSpCas9	positive selection	3020270
408754	408777	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCCTGCCTTCAGTCCAGTGG	SIGIRR	ENSG00000185187	-0.35519341976711133	[3,3]	[1,2]	-5	hSpCas9	positive selection	3020271
408096	408119	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGAAGCTGATGTTCTGGATGG	SIGIRR	ENSG00000185187	0.2490124647245079	[5,5]	[6,5]	5	hSpCas9	positive selection	3020272
408717	408740	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TAGTGGCCCCCAATTCCCAATGG	SIGIRR	ENSG00000185187	-0.3805965662575205	[3,3]	[1,2]	-5	hSpCas9	positive selection	3020273
407873	407896	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.22026539194902875	[3,3]	[4,1]	4	hSpCas9	positive selection	3088128
408754	408777	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCCTGCCTTCAGTCCAGTGG	SIGIRR	ENSG00000185187	-0.02744011640858461	[3,3]	[4,0]	0	hSpCas9	positive selection	3088129
408096	408119	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGAAGCTGATGTTCTGGATGG	SIGIRR	ENSG00000185187	0.3343963564472674	[5,5]	[5,4]	6	hSpCas9	positive selection	3088130
408717	408740	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TAGTGGCCCCCAATTCCCAATGG	SIGIRR	ENSG00000185187	0.4654862919305799	[3,3]	[2,3]	7	hSpCas9	positive selection	3088131
408694	408717		-	24336571	A375	resistance to PLX after 7 days	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.34054401760444897	[10,13]	[14,15]	8	hSpCas9	positive selection	3144218
408152	408175		+	24336571	A375	resistance to PLX after 7 days	CACGTTGACCCCCAGGACACTGG	SIGIRR	ENSG00000185187	-0.25595090406805254	[12,11]	[7,12]	-7	hSpCas9	positive selection	3144219
408072	408095		-	24336571	A375	resistance to PLX after 7 days	TCCTTCACTCTTCAGAGAGCTGG	SIGIRR	ENSG00000185187	-0.030819895654594587	[7,11]	[8,10]	-1	hSpCas9	positive selection	3144220
408687	408710		+	24336571	A375	resistance to PLX after 7 days	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.04102437218067023	[14,15]	[12,16]	-1	hSpCas9	positive selection	3144221
408694	408717		-	24336571	A375	resistance to PLX after 14 days	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	1.3529125271526334	[9,10]	[14,9]	8	hSpCas9	positive selection	3202011
408152	408175		+	24336571	A375	resistance to PLX after 14 days	CACGTTGACCCCCAGGACACTGG	SIGIRR	ENSG00000185187	-0.02560661732651137	[13,7]	[4,3]	0	hSpCas9	positive selection	3202012
408072	408095		-	24336571	A375	resistance to PLX after 14 days	TCCTTCACTCTTCAGAGAGCTGG	SIGIRR	ENSG00000185187	-0.1294388861636364	[8,11]	[3,3]	-1	hSpCas9	positive selection	3202013
408687	408710		+	24336571	A375	resistance to PLX after 14 days	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.42623366786048567	[12,16]	[5,3]	-5	hSpCas9	positive selection	3202014
408694	408717		-	24336571	A375	viability after 7 days	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.2256664504998862	[10]	[10,13]	3	hSpCas9	negative selection	3259804
408152	408175		+	24336571	A375	viability after 7 days	CACGTTGACCCCCAGGACACTGG	SIGIRR	ENSG00000185187	0.46300585760729507	[9]	[12,11]	7	hSpCas9	negative selection	3259805
408072	408095		-	24336571	A375	viability after 7 days	TCCTTCACTCTTCAGAGAGCTGG	SIGIRR	ENSG00000185187	0.1072813359004558	[9]	[7,11]	1	hSpCas9	negative selection	3259806
408687	408710		+	24336571	A375	viability after 7 days	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.22439752263357426	[18]	[14,15]	-3	hSpCas9	negative selection	3259807
408694	408717		-	24336571	A375	viability after 14 days	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.03795819561983707	[10]	[9,10]	0	hSpCas9	negative selection	3317597
408152	408175		+	24336571	A375	viability after 14 days	CACGTTGACCCCCAGGACACTGG	SIGIRR	ENSG00000185187	0.2622735760943882	[9]	[13,7]	3	hSpCas9	negative selection	3317598
408072	408095		-	24336571	A375	viability after 14 days	TCCTTCACTCTTCAGAGAGCTGG	SIGIRR	ENSG00000185187	0.11112731640472473	[9]	[8,11]	1	hSpCas9	negative selection	3317599
408687	408710		+	24336571	A375	viability after 14 days	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.24456623507869618	[18]	[12,16]	-3	hSpCas9	negative selection	3317600
408687	408710	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.7705797851240493	[260,260]	[0,0]	-5	hSpCas9	positive selection	3392418
407940	407963	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.6674862921599458	[242,242]	[0,0]	-4	hSpCas9	positive selection	3392419
407826	407849	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	1.7027373597681978	[46,46]	[0,0]	7	hSpCas9	positive selection	3392420
407872	407895	11	+	26780180	HT29	viability (Avana library 4 designs)	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.30300237571076	[]	[]	1	hSpCas9	negative selection	3458776
408754	408777	11	-	26780180	HT29	viability (Avana library 4 designs)	GCTCCCTGCCTTCAGTCCAGTGG	SIGIRR	ENSG00000185187	0.154628335216206	[]	[]	0	hSpCas9	negative selection	3458777
408095	408118	11	+	26780180	HT29	viability (Avana library 4 designs)	GGAGAAGCTGATGTTCTGGATGG	SIGIRR	ENSG00000185187	-0.769824642867874	[]	[]	-9	hSpCas9	negative selection	3458778
408716	408739	11	+	26780180	HT29	viability (Avana library 4 designs)	TAGTGGCCCCCAATTCCCAATGG	SIGIRR	ENSG00000185187	0.307772190060568	[]	[]	1	hSpCas9	negative selection	3458779
408716	408739	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	TAGTGGCCCCCAATTCCCAATGG	SIGIRR	ENSG00000185187	1.04821139263484	[]	[]	1	hSpCas9	negative selection	3558382
407872	407895	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	1.08841898362944	[]	[]	1	hSpCas9	negative selection	3558383
408754	408777	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCCTGCCTTCAGTCCAGTGG	SIGIRR	ENSG00000185187	7.8460953609361	[]	[]	9	hSpCas9	negative selection	3558384
408095	408118	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGAAGCTGATGTTCTGGATGG	SIGIRR	ENSG00000185187	3.36299267190146	[]	[]	5	hSpCas9	negative selection	3558385
408856	408879	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGACGGGGAGAGGAAGTCAGGGG	SIGIRR	ENSG00000185187	-9.26067417940662	[]	[]	-7	hSpCas9	negative selection	3558386
408160	408183	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTGTGTCCAGTGTCCTGGGGG	SIGIRR	ENSG00000185187	-1.04449784988029	[]	[]	-1	hSpCas9	negative selection	3558387
408716	408739	11	+	26780180	A375	viability (Avana lentiGuide)	TAGTGGCCCCCAATTCCCAATGG	SIGIRR	ENSG00000185187	-0.873285790689754	[]	[]	-1	hSpCas9	negative selection	3667041
407872	407895	11	+	26780180	A375	viability (Avana lentiGuide)	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	-5.07493618288459	[]	[]	-8	hSpCas9	negative selection	3667042
408754	408777	11	-	26780180	A375	viability (Avana lentiGuide)	GCTCCCTGCCTTCAGTCCAGTGG	SIGIRR	ENSG00000185187	-2.49123726403479	[]	[]	-4	hSpCas9	negative selection	3667043
408095	408118	11	+	26780180	A375	viability (Avana lentiGuide)	GGAGAAGCTGATGTTCTGGATGG	SIGIRR	ENSG00000185187	-1.60412543463675	[]	[]	-3	hSpCas9	negative selection	3667044
408856	408879	11	+	26780180	A375	viability (Avana lentiGuide)	AGACGGGGAGAGGAAGTCAGGGG	SIGIRR	ENSG00000185187	15.1312667199708	[]	[]	8	hSpCas9	negative selection	3667045
408160	408183	11	-	26780180	A375	viability (Avana lentiGuide)	GCTTGTGTCCAGTGTCCTGGGGG	SIGIRR	ENSG00000185187	0.571794263476866	[]	[]	0	hSpCas9	negative selection	3667046
408716	408739	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAGTGGCCCCCAATTCCCAATGG	SIGIRR	ENSG00000185187	-0.39859957236077176	[4]	[3,2]	-5	hSpCas9	positive selection	3775648
407872	407895	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.06403252011690362	[5]	[6,4]	1	hSpCas9	positive selection	3775649
408754	408777	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCCTGCCTTCAGTCCAGTGG	SIGIRR	ENSG00000185187	0.32739149512672827	[4]	[5,4]	8	hSpCas9	positive selection	3775650
408095	408118	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGAAGCTGATGTTCTGGATGG	SIGIRR	ENSG00000185187	0.1372391240205471	[6]	[6,7]	3	hSpCas9	positive selection	3775651
408856	408879	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGACGGGGAGAGGAAGTCAGGGG	SIGIRR	ENSG00000185187	-0.056796359645419514	[0]	[0,0]	-1	hSpCas9	positive selection	3775652
408160	408183	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTGTGTCCAGTGTCCTGGGGG	SIGIRR	ENSG00000185187	-0.06590611712165234	[5]	[5,4]	-1	hSpCas9	positive selection	3775653
408716	408739	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAGTGGCCCCCAATTCCCAATGG	SIGIRR	ENSG00000185187	0.07710388526325787	[4]	[4,3]	1	hSpCas9	positive selection	3884255
407872	407895	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.0659492825562997	[5]	[4,3]	1	hSpCas9	positive selection	3884256
408754	408777	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCCTGCCTTCAGTCCAGTGG	SIGIRR	ENSG00000185187	0.21863340806374448	[5]	[5,4]	5	hSpCas9	positive selection	3884257
408095	408118	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGAAGCTGATGTTCTGGATGG	SIGIRR	ENSG00000185187	0.27532755462953273	[7]	[7,7]	7	hSpCas9	positive selection	3884258
408856	408879	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGACGGGGAGAGGAAGTCAGGGG	SIGIRR	ENSG00000185187	-1.344988045690856	[3]	[1,0]	-9	hSpCas9	positive selection	3884259
408160	408183	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTGTGTCCAGTGTCCTGGGGG	SIGIRR	ENSG00000185187	0.1597097627729021	[6]	[6,6]	4	hSpCas9	positive selection	3884260
408694	408717	11	-	26780180	A375	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	1.23151122935611	[]	[]	6	hSpCas9	negative selection	3994322
407826	407849	11	+	26780180	A375	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	1.19534730899745	[]	[]	6	hSpCas9	negative selection	3994323
407416	407439	11	+	26780180	A375	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.990192488802357	[]	[]	4	hSpCas9	negative selection	3994324
407940	407963	11	-	26780180	A375	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	1.25290957784696	[]	[]	6	hSpCas9	negative selection	3994325
407482	407505	11	-	26780180	A375	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	1.34639596148917	[]	[]	7	hSpCas9	negative selection	3994326
408687	408710	11	+	26780180	A375	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	1.2008750799366	[]	[]	6	hSpCas9	negative selection	3994327
408694	408717	11	-	26780180	HT29	viability (GeCKOv2 library)	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	1.63648285546225	[]	[]	8	hSpCas9	negative selection	4102288
407826	407849	11	+	26780180	HT29	viability (GeCKOv2 library)	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	1.72596586646631	[]	[]	8	hSpCas9	negative selection	4102289
407416	407439	11	+	26780180	HT29	viability (GeCKOv2 library)	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	1.35268693264897	[]	[]	7	hSpCas9	negative selection	4102290
407940	407963	11	-	26780180	HT29	viability (GeCKOv2 library)	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.787690988480227	[]	[]	3	hSpCas9	negative selection	4102291
407482	407505	11	-	26780180	HT29	viability (GeCKOv2 library)	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	1.09211392785964	[]	[]	5	hSpCas9	negative selection	4102292
408687	408710	11	+	26780180	HT29	viability (GeCKOv2 library)	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	0.514630084613274	[]	[]	1	hSpCas9	negative selection	4102293
408694	408717	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.3220290917185712	[3]	[2,3]	7	hSpCas9	positive selection	4170156
408152	408175	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACGTTGACCCCCAGGACACTGG	SIGIRR	ENSG00000185187	-0.13568210954951207	[3]	[1,2]	-3	hSpCas9	positive selection	4170157
408072	408095	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCTTCACTCTTCAGAGAGCTGG	SIGIRR	ENSG00000185187	0.15923421167756197	[2]	[2,1]	4	hSpCas9	positive selection	4170158
408687	408710	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	0.02815404712375618	[3]	[2,2]	0	hSpCas9	positive selection	4170159
408694	408717	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.6610522780951922	[3]	[0,0,0,3]	4	hSpCas9	positive selection	4234178
408152	408175	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACGTTGACCCCCAGGACACTGG	SIGIRR	ENSG00000185187	0.290063098426025	[3]	[0,2,4,0]	2	hSpCas9	positive selection	4234179
408072	408095	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCTTCACTCTTCAGAGAGCTGG	SIGIRR	ENSG00000185187	0.0037785426365835872	[3]	[1,0,3,0]	0	hSpCas9	positive selection	4234180
408687	408710	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.6471996674035502	[4]	[1,0,0,0]	-8	hSpCas9	positive selection	4234181
407416	407439	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	-0.6496003597918315	[1]	[0,0]	-9	hSpCas9	positive selection	4297750
407482	407505	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.019029863363243277	[3]	[3,2]	0	hSpCas9	positive selection	4297751
408694	408717	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.5754290617113311	[2]	[1,0]	-8	hSpCas9	positive selection	4297752
408687	408710	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	0.21796102683513968	[3]	[3,2]	4	hSpCas9	positive selection	4362004
407940	407963	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.1465485668990002	[3]	[3,1]	3	hSpCas9	positive selection	4362005
407826	407849	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.3347936815410857	[1]	[0,0]	-6	hSpCas9	positive selection	4362006
407482	407504	11	-	27760321	OCIAML3	viability	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.22197387472081218	[590,528]	[315,451]	-2	hSpCas9	negative selection	4438934
407507	407529	11	+	27760321	OCIAML3	viability	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	-1.1873781515255146	[1076,895]	[276,415]	-8	hSpCas9	negative selection	4438935
407870	407892	11	+	27760321	OCIAML3	viability	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	0.4954974104169767	[532,388]	[400,636]	6	hSpCas9	negative selection	4438936
408146	408168	11	+	27760321	OCIAML3	viability	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	0.25862983062222744	[637,530]	[409,719]	3	hSpCas9	negative selection	4438937
408691	408713	11	+	27760321	OCIAML3	viability	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	-0.006114404726682038	[396,394]	[169,490]	0	hSpCas9	negative selection	4438938
407482	407504	11	-	27760321	OCIAML2	viability	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.3493440322434879	[590,528]	[333,382]	-4	hSpCas9	negative selection	4522397
407507	407529	11	+	27760321	OCIAML2	viability	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	-0.3266354652903375	[1076,895]	[517,785]	-4	hSpCas9	negative selection	4522398
407870	407892	11	+	27760321	OCIAML2	viability	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	-0.8021252443658925	[532,388]	[172,262]	-7	hSpCas9	negative selection	4522399
408146	408168	11	+	27760321	OCIAML2	viability	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	0.018479569271552143	[637,530]	[510,431]	0	hSpCas9	negative selection	4522400
408691	408713	11	+	27760321	OCIAML2	viability	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	-0.2840614523171078	[396,394]	[256,272]	-3	hSpCas9	negative selection	4522401
407482	407504	11	-	27760321	MV411	viability	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.2202127066809706	[590,528]	[359,534]	1	hSpCas9	negative selection	4605860
407507	407529	11	+	27760321	MV411	viability	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	0.131948014393942	[1076,895]	[601,872]	0	hSpCas9	negative selection	4605861
407870	407892	11	+	27760321	MV411	viability	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	0.4614322837113489	[532,388]	[511,268]	3	hSpCas9	negative selection	4605862
408146	408168	11	+	27760321	MV411	viability	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	-0.24035167688476933	[637,530]	[251,434]	-2	hSpCas9	negative selection	4605863
408691	408713	11	+	27760321	MV411	viability	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	0.8048064363663504	[396,394]	[106,984]	6	hSpCas9	negative selection	4605864
407482	407504	11	-	27760321	HL60	viability	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.5905703171667721	[590,528]	[266,341]	-6	hSpCas9	negative selection	4689323
407507	407529	11	+	27760321	HL60	viability	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	0.05067341214083343	[1076,895]	[867,791]	0	hSpCas9	negative selection	4689324
407870	407892	11	+	27760321	HL60	viability	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	-1.1012962066427678	[532,388]	[201,143]	-8	hSpCas9	negative selection	4689325
408146	408168	11	+	27760321	HL60	viability	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	0.3999267614934945	[637,530]	[521,738]	5	hSpCas9	negative selection	4689326
408691	408713	11	+	27760321	HL60	viability	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	-0.685323447017849	[396,394]	[293,103]	-6	hSpCas9	negative selection	4689327
407482	407504	11	-	27760321	HT1080	viability	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.2538755117535721	[528,412]	[17,448]	1	hSpCas9	negative selection	4772786
407507	407529	11	+	27760321	HT1080	viability	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	0.8345926154010945	[895,698]	[356,795]	4	hSpCas9	negative selection	4772787
407870	407892	11	+	27760321	HT1080	viability	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	-1.50490757720226	[388,303]	[19,79]	-5	hSpCas9	negative selection	4772788
408146	408168	11	+	27760321	HT1080	viability	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	-0.17231331791418503	[530,414]	[150,184]	-1	hSpCas9	negative selection	4772789
408691	408713	11	+	27760321	HT1080	viability	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	-3.749907193026507	[394,307]	[18,0]	-8	hSpCas9	negative selection	4772790
407482	407504	11	-	27760321	HT29	viability after 7 days	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.06008978574292678	[528,412]	[522,548,658]	-1	hSpCas9	negative selection	4856249
407507	407529	11	+	27760321	HT29	viability after 7 days	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	-0.26127407961330074	[895,698]	[1268,684,675]	-4	hSpCas9	negative selection	4856250
407870	407892	11	+	27760321	HT29	viability after 7 days	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	0.4691622557837867	[388,303]	[912,532,450]	7	hSpCas9	negative selection	4856251
408146	408168	11	+	27760321	HT29	viability after 7 days	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	0.20014175290368558	[530,414]	[644,888,557]	3	hSpCas9	negative selection	4856252
408691	408713	11	+	27760321	HT29	viability after 7 days	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	0.2629951608977308	[394,307]	[752,326,574]	4	hSpCas9	negative selection	4856253
407482	407504	11	-	27760321	HT29	viability after 25 days	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.16784786014314584	[528,412]	[740,506,550]	1	hSpCas9	negative selection	4939712
407507	407529	11	+	27760321	HT29	viability after 25 days	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	0.6062145024702039	[895,698]	[1382,1322,1461]	6	hSpCas9	negative selection	4939713
407870	407892	11	+	27760321	HT29	viability after 25 days	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	1.1249747716137106	[388,303]	[866,1027,674]	9	hSpCas9	negative selection	4939714
408146	408168	11	+	27760321	HT29	viability after 25 days	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	1.0534320413410092	[530,414]	[1095,1155,1112]	9	hSpCas9	negative selection	4939715
408691	408713	11	+	27760321	HT29	viability after 25 days	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	0.6529442290831159	[394,307]	[734,462,695]	7	hSpCas9	negative selection	4939716
407482	407504	11	-	27760321	HT29	viability after 22 days	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.0717876945381205	[528,412]	[511,563,477]	0	hSpCas9	negative selection	5023175
407507	407529	11	+	27760321	HT29	viability after 22 days	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	0.7371596739555937	[895,698]	[1603,1505,1497]	8	hSpCas9	negative selection	5023176
407870	407892	11	+	27760321	HT29	viability after 22 days	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	0.7637837266488074	[388,303]	[626,735,678]	8	hSpCas9	negative selection	5023177
408146	408168	11	+	27760321	HT29	viability after 22 days	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	0.8711529143100845	[530,414]	[880,1017,1105]	8	hSpCas9	negative selection	5023178
408691	408713	11	+	27760321	HT29	viability after 22 days	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	0.18167496757972038	[394,307]	[368,558,456]	1	hSpCas9	negative selection	5023179
407482	407504	11	-	27760321	HT29	viability after 19 days	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.2106603620399791	[528,412]	[451,429,510]	-2	hSpCas9	negative selection	5106638
407507	407529	11	+	27760321	HT29	viability after 19 days	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	0.5376459866195047	[895,698]	[1641,1058,1303]	5	hSpCas9	negative selection	5106639
407870	407892	11	+	27760321	HT29	viability after 19 days	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	1.1885382730176985	[388,303]	[740,1281,677]	9	hSpCas9	negative selection	5106640
408146	408168	11	+	27760321	HT29	viability after 19 days	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	0.558210770622743	[530,414]	[1052,831,540]	5	hSpCas9	negative selection	5106641
408691	408713	11	+	27760321	HT29	viability after 19 days	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	0.6219694666875217	[394,307]	[354,481,976]	6	hSpCas9	negative selection	5106642
407482	407504	11	-	27760321	HT29	viability after 16 days	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.20428615131853256	[528,412]	[659,389,342]	-2	hSpCas9	negative selection	5190101
407507	407529	11	+	27760321	HT29	viability after 16 days	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	0.3251828718218037	[895,698]	[1508,817,1070]	3	hSpCas9	negative selection	5190102
407870	407892	11	+	27760321	HT29	viability after 16 days	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	1.0912882387591638	[388,303]	[687,1015,755]	9	hSpCas9	negative selection	5190103
408146	408168	11	+	27760321	HT29	viability after 16 days	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	0.7722345205048737	[530,414]	[988,772,960]	8	hSpCas9	negative selection	5190104
408691	408713	11	+	27760321	HT29	viability after 16 days	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	0.4190109391545079	[394,307]	[463,424,684]	5	hSpCas9	negative selection	5190105
407482	407504	11	-	27760321	HT29	viability after 13 days	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.09285299754638715	[528,412]	[510,581,447]	-1	hSpCas9	negative selection	5273564
407507	407529	11	+	27760321	HT29	viability after 13 days	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	0.05090099916065949	[895,698]	[992,1180,715]	0	hSpCas9	negative selection	5273565
407870	407892	11	+	27760321	HT29	viability after 13 days	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	0.2967287415068973	[388,303]	[571,531,383]	4	hSpCas9	negative selection	5273566
408146	408168	11	+	27760321	HT29	viability after 13 days	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	0.33722998820473254	[530,414]	[794,616,668]	4	hSpCas9	negative selection	5273567
408691	408713	11	+	27760321	HT29	viability after 13 days	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	0.3026679638680651	[394,307]	[403,568,533]	4	hSpCas9	negative selection	5273568
407482	407504	11	-	27760321	HT29	viability after 10 days	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.10103759889775688	[528,412]	[762,555,330]	-1	hSpCas9	negative selection	5357027
407507	407529	11	+	27760321	HT29	viability after 10 days	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	0.31480266426668346	[895,698]	[1208,1506,1011]	4	hSpCas9	negative selection	5357028
407870	407892	11	+	27760321	HT29	viability after 10 days	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	0.5787087230194169	[388,303]	[615,710,613]	7	hSpCas9	negative selection	5357029
408146	408168	11	+	27760321	HT29	viability after 10 days	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	0.46007974380951816	[530,414]	[788,897,753]	6	hSpCas9	negative selection	5357030
408691	408713	11	+	27760321	HT29	viability after 10 days	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	0.21490744835676961	[394,307]	[481,402,636]	3	hSpCas9	negative selection	5357031
407482	407504	11	-	27760321	MOLM13	viability	TTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.03160642047880846	[590,528]	[52,551]	0	hSpCas9	negative selection	5440490
407507	407529	11	+	27760321	MOLM13	viability	CACGAACTTGCGGTCCTCGGGG	SIGIRR	ENSG00000185187	-0.6174586462141745	[1076,895]	[135,552]	-4	hSpCas9	negative selection	5440491
407870	407892	11	+	27760321	MOLM13	viability	CGGCACTTGACATAGAGCAGGG	SIGIRR	ENSG00000185187	-0.31976692720141414	[532,388]	[274,147]	-2	hSpCas9	negative selection	5440492
408146	408168	11	+	27760321	MOLM13	viability	GCTGGTCACGTTGACCCCCAGG	SIGIRR	ENSG00000185187	0.5266465902370575	[637,530]	[431,507]	3	hSpCas9	negative selection	5440493
408691	408713	11	+	27760321	MOLM13	viability	TTACCAGGAGTACTCGTGGAGG	SIGIRR	ENSG00000185187	-1.24134194763011	[396,394]	[184,17]	-6	hSpCas9	negative selection	5440494
407076	407099	11	+	27661255	K562	viability	GCACCAGGCCCGGCTCAGGAAGG	SIGIRR	ENSG00000185187	0.18392781229794297	[507,574]	[533,452]	6	dCas9-KRAB	negative selection	5511009
407133	407156	11	+	27661255	K562	viability	GCTCAGGTTCACCAAGAGGTCGG	SIGIRR	ENSG00000185187	0.9622515603227453	[24,39]	[47,51]	9	dCas9-KRAB	negative selection	5511010
414613	414636	11	+	27661255	K562	viability	GTCACAGAGCCTAGGACCACAGG	SIGIRR	ENSG00000185187	0.11575419133019389	[716,855]	[751,615]	4	dCas9-KRAB	negative selection	5511011
406792	406815	11	-	27661255	K562	viability	GCTAGCGGCGGGTTAGAGATGGG	SIGIRR	ENSG00000185187	0.4368252779549972	[632,553]	[713,582]	9	dCas9-KRAB	negative selection	5511012
414481	414504	11	-	27661255	K562	viability	GGAGGTGCAAGTGTGCACACGGG	SIGIRR	ENSG00000185187	0.2749907752118677	[420,597]	[524,458]	8	dCas9-KRAB	negative selection	5511013
407416	407439	11	+	27260156	BXPC3	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.3976959587390403	[140]	[156,142,251,236]	8	hSpCas9	negative selection	5570210
407482	407505	11	-	27260156	BXPC3	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.09694500423118102	[679]	[647,594,613,821]	-2	hSpCas9	negative selection	5570211
408694	408717	11	-	27260156	BXPC3	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.10725493800927233	[268]	[206,304,340,376]	2	hSpCas9	negative selection	5570212
408687	408710	11	+	27260156	BXPC3	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.2361043107366152	[855]	[594,802,762,906]	-5	hSpCas9	negative selection	5634464
407940	407963	11	-	27260156	BXPC3	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.040623524304605446	[561]	[571,527,549,641]	-1	hSpCas9	negative selection	5634465
407826	407849	11	+	27260156	BXPC3	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	0.012443353128763102	[136]	[142,172,120,136]	0	hSpCas9	negative selection	5634466
407416	407439	11	+	27260156	A673	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.5189494247103679	[140]	[289,183,270,230]	9	hSpCas9	negative selection	5691461
407482	407505	11	-	27260156	A673	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.0054042174446079505	[679]	[802,636,866,955]	0	hSpCas9	negative selection	5691462
408694	408717	11	-	27260156	A673	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.018961268019450528	[268]	[291,338,372,297]	0	hSpCas9	negative selection	5691463
408687	408710	11	+	27260156	A673	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.1757146912617592	[855]	[1081,871,925,770]	-4	hSpCas9	negative selection	5755715
407940	407963	11	-	27260156	A673	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.05186369591900192	[561]	[754,527,785,739]	1	hSpCas9	negative selection	5755716
407826	407849	11	+	27260156	A673	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.5377889781140446	[136]	[139,107,100,106]	-8	hSpCas9	negative selection	5755717
407416	407439	11	+	27260156	A375	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.45514289125622276	[140]	[204,364,204,154]	6	hSpCas9	negative selection	5812712
407482	407505	11	-	27260156	A375	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.17448439629534201	[679]	[865,709,937,343]	-3	hSpCas9	negative selection	5812713
408694	408717	11	-	27260156	A375	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.41836336063203894	[268]	[185,283,296,184]	-5	hSpCas9	negative selection	5812714
408687	408710	11	+	27260156	A375	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.22081103204030728	[855]	[1134,1006,690,643]	-3	hSpCas9	negative selection	5876966
407940	407963	11	-	27260156	A375	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.21910822324202678	[561]	[562,705,465,540]	-3	hSpCas9	negative selection	5876967
407826	407849	11	+	27260156	A375	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.2546689231114996	[136]	[114,143,169,110]	-4	hSpCas9	negative selection	5876968
407416	407439	11	+	27260156	COLO741	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	-0.26444904527553637	[140]	[148,170,130]	-5	hSpCas9	negative selection	5933963
407482	407505	11	-	27260156	COLO741	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.061415628331092265	[679]	[1005,937,790]	1	hSpCas9	negative selection	5933964
408694	408717	11	-	27260156	COLO741	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.13252863901272383	[268]	[262,367,480]	3	hSpCas9	negative selection	5933965
408687	408710	11	+	27260156	COLO741	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.3560418252905718	[855]	[782,1074,708]	-6	hSpCas9	negative selection	5998217
407940	407963	11	-	27260156	COLO741	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.13476209303230924	[561]	[960,688,731]	3	hSpCas9	negative selection	5998218
407826	407849	11	+	27260156	COLO741	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.2608857271977152	[136]	[171,92,172]	-5	hSpCas9	negative selection	5998219
407416	407439	11	+	27260156	CAL120	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.291396983748921	[140]	[256,96,294]	4	hSpCas9	negative selection	6055214
407482	407505	11	-	27260156	CAL120	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.13023804422767815	[679]	[792,694,832]	-2	hSpCas9	negative selection	6055215
408694	408717	11	-	27260156	CAL120	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.130926234974182	[268]	[431,404,273]	2	hSpCas9	negative selection	6055216
408687	408710	11	+	27260156	CAL120	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.305825229961884	[855]	[939,929,728]	-4	hSpCas9	negative selection	6119468
407940	407963	11	-	27260156	CAL120	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.032539648804353616	[561]	[468,549,993]	0	hSpCas9	negative selection	6119469
407826	407849	11	+	27260156	CAL120	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.11232107392785484	[136]	[175,207,92]	-2	hSpCas9	negative selection	6119470
407416	407439	11	+	27260156	CADOES1	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	-0.21521739908954518	[140]	[147,102,106,92]	-4	hSpCas9	negative selection	6176465
407482	407505	11	-	27260156	CADOES1	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.2988762705125887	[679]	[586,552,384,531]	-5	hSpCas9	negative selection	6176466
408694	408717	11	-	27260156	CADOES1	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.3529357792928844	[268]	[306,241,229,505]	6	hSpCas9	negative selection	6176467
408687	408710	11	+	27260156	CADOES1	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.2956741576826557	[855]	[611,553,760,667]	-5	hSpCas9	negative selection	6240719
407940	407963	11	-	27260156	CADOES1	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.1539469916712083	[561]	[288,606,434,551]	-3	hSpCas9	negative selection	6240720
407826	407849	11	+	27260156	CADOES1	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	0.061463232987096106	[136]	[190,139,111,86]	1	hSpCas9	negative selection	6240721
407416	407439	11	+	27260156	EWS502	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.44882869490173594	[140]	[188,209,281,130]	7	hSpCas9	negative selection	6297716
407482	407505	11	-	27260156	EWS502	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.34016391782712274	[679]	[376,585,653,688]	-5	hSpCas9	negative selection	6297717
408694	408717	11	-	27260156	EWS502	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.19197786806304218	[268]	[320,310,392,273]	3	hSpCas9	negative selection	6297718
408687	408710	11	+	27260156	EWS502	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.3491170373092275	[855]	[639,711,792,708]	-6	hSpCas9	negative selection	6361970
407940	407963	11	-	27260156	EWS502	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.016187570442360105	[561]	[634,433,589,701]	0	hSpCas9	negative selection	6361971
407826	407849	11	+	27260156	EWS502	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.44784604191953803	[136]	[136,94,107,79]	-6	hSpCas9	negative selection	6361972
407416	407439	11	+	27260156	EW8	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.029526193276965707	[140]	[115,109,98,143]	0	hSpCas9	negative selection	6418967
407482	407505	11	-	27260156	EW8	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.22094434683898395	[679]	[715,446,377,391]	-4	hSpCas9	negative selection	6418968
408694	408717	11	-	27260156	EW8	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.08415718306159248	[268]	[202,223,239,251]	1	hSpCas9	negative selection	6418969
408687	408710	11	+	27260156	EW8	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	0.00783833528259037	[855]	[887,477,617,836]	0	hSpCas9	negative selection	6483221
407940	407963	11	-	27260156	EW8	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.046314989404499685	[561]	[429,389,430,511]	-1	hSpCas9	negative selection	6483222
407826	407849	11	+	27260156	EW8	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.48972935055165157	[136]	[93,90,65,68]	-7	hSpCas9	negative selection	6483223
407416	407439	11	+	27260156	CORL105	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.6563825325119048	[140]	[294,179,377,208]	9	hSpCas9	negative selection	6540218
407482	407505	11	-	27260156	CORL105	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.205666684999804	[679]	[670,655,791,657]	-4	hSpCas9	negative selection	6540219
408694	408717	11	-	27260156	CORL105	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.02235021003447024	[268]	[190,360,365,362]	0	hSpCas9	negative selection	6540220
408687	408710	11	+	27260156	CORL105	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.33649061649858436	[855]	[834,633,922,806]	-6	hSpCas9	negative selection	6604472
407940	407963	11	-	27260156	CORL105	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.10508734779827678	[561]	[895,569,665,700]	2	hSpCas9	negative selection	6604473
407826	407849	11	+	27260156	CORL105	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	0.03447937181372929	[136]	[140,234,107,161]	0	hSpCas9	negative selection	6604474
407416	407439	11	+	27260156	HS294T	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	1.2955092482794945	[140]	[79,112,92,278]	9	hSpCas9	negative selection	6661469
407482	407505	11	-	27260156	HS294T	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.3210019070140918	[679]	[253,328,267,496]	4	hSpCas9	negative selection	6661470
408694	408717	11	-	27260156	HS294T	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.6149659063682366	[268]	[269,94,113,146]	7	hSpCas9	negative selection	6661471
408687	408710	11	+	27260156	HS294T	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.29004931178020277	[855]	[288,259,257,273]	-4	hSpCas9	negative selection	6725723
407940	407963	11	-	27260156	HS294T	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.6163519859221047	[561]	[248,246,525,317]	7	hSpCas9	negative selection	6725724
407826	407849	11	+	27260156	HS294T	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	0.05903536967456691	[136]	[36,24,42,130]	0	hSpCas9	negative selection	6725725
407416	407439	11	+	27260156	HCC44	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.29037275843321364	[140]	[113,174,285,213]	5	hSpCas9	negative selection	6782720
407482	407505	11	-	27260156	HCC44	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.1554469693447792	[679]	[705,664,694,695]	-3	hSpCas9	negative selection	6782721
408694	408717	11	-	27260156	HCC44	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.13544831823603098	[268]	[275,190,358,304]	-2	hSpCas9	negative selection	6782722
408687	408710	11	+	27260156	HCC44	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.5252525627005837	[855]	[560,453,1093,669]	-7	hSpCas9	negative selection	6846974
407940	407963	11	-	27260156	HCC44	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.21465647587536363	[561]	[600,674,799,870]	3	hSpCas9	negative selection	6846975
407826	407849	11	+	27260156	HCC44	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.14662465705087158	[136]	[214,69,198,102]	-2	hSpCas9	negative selection	6846976
407416	407439	11	+	27260156	G402	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.2805900724984993	[140]	[139,153,255,268]	3	hSpCas9	negative selection	6903971
407482	407505	11	-	27260156	G402	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.7699115460675423	[679]	[621,350,534,449]	-7	hSpCas9	negative selection	6903972
408694	408717	11	-	27260156	G402	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.2017819228686084	[268]	[151,325,411,235]	-3	hSpCas9	negative selection	6903973
408687	408710	11	+	27260156	G402	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.383879136851472	[855]	[1101,493,562,1052]	-5	hSpCas9	negative selection	6968225
407940	407963	11	-	27260156	G402	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.26035142336713946	[561]	[906,433,411,574]	-3	hSpCas9	negative selection	6968226
407826	407849	11	+	27260156	G402	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.8795858805563903	[136]	[39,80,54,174]	-8	hSpCas9	negative selection	6968227
407416	407439	11	+	27260156	L33	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.01443349569142005	[140]	[140,59,54,193]	0	hSpCas9	negative selection	7025222
407482	407505	11	-	27260156	L33	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.2496896952684794	[679]	[791,293,587,789]	5	hSpCas9	negative selection	7025223
408694	408717	11	-	27260156	L33	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.37038036510812056	[268]	[126,81,195,195]	-7	hSpCas9	negative selection	7025224
408687	408710	11	+	27260156	L33	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.31560972078351746	[855]	[614,373,384,612]	-6	hSpCas9	negative selection	7089476
407940	407963	11	-	27260156	L33	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.21294267190867416	[561]	[633,206,509,655]	4	hSpCas9	negative selection	7089477
407826	407849	11	+	27260156	L33	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.10992623262527035	[136]	[148,49,95,83]	-2	hSpCas9	negative selection	7089478
407416	407439	11	+	27260156	K562	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.5309480516025227	[140]	[167,213,281,71]	6	hSpCas9	negative selection	7146473
407482	407505	11	-	27260156	K562	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.14638425112969816	[679]	[993,379,488,364]	-2	hSpCas9	negative selection	7146474
408694	408717	11	-	27260156	K562	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.11736501325979343	[268]	[165,320,167,362]	1	hSpCas9	negative selection	7146475
408687	408710	11	+	27260156	K562	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.3181252302848464	[855]	[777,518,690,471]	-4	hSpCas9	negative selection	7210727
407940	407963	11	-	27260156	K562	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.11702170888403252	[561]	[460,644,296,445]	-1	hSpCas9	negative selection	7210728
407826	407849	11	+	27260156	K562	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.09900465854359664	[136]	[110,2,110,210]	-1	hSpCas9	negative selection	7210729
407416	407439	11	+	27260156	HT29	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.28391094258613236	[140]	[240,184,246,165]	5	hSpCas9	negative selection	7267724
407482	407505	11	-	27260156	HT29	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.21539031980498335	[679]	[823,675,723,633]	-4	hSpCas9	negative selection	7267725
408694	408717	11	-	27260156	HT29	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.26083727920349586	[268]	[348,405,412,393]	5	hSpCas9	negative selection	7267726
408687	408710	11	+	27260156	HT29	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.14747514733004208	[855]	[1133,882,875,875]	-3	hSpCas9	negative selection	7331978
407940	407963	11	-	27260156	HT29	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.09140002069404565	[561]	[825,656,569,535]	-2	hSpCas9	negative selection	7331979
407826	407849	11	+	27260156	HT29	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.5217692713838147	[136]	[144,83,120,112]	-7	hSpCas9	negative selection	7331980
407416	407439	11	+	27260156	MHHES1	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.40113518909022217	[140]	[207,162,216,234]	7	hSpCas9	negative selection	7388975
407482	407505	11	-	27260156	MHHES1	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.13018076080451635	[679]	[855,794,500,665]	-2	hSpCas9	negative selection	7388976
408694	408717	11	-	27260156	MHHES1	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.08297149998820563	[268]	[270,422,269,316]	1	hSpCas9	negative selection	7388977
408687	408710	11	+	27260156	MHHES1	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	0.05356075099157809	[855]	[1219,1153,863,823]	1	hSpCas9	negative selection	7453229
407940	407963	11	-	27260156	MHHES1	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.00019967383533869842	[561]	[595,954,532,493]	0	hSpCas9	negative selection	7453230
407826	407849	11	+	27260156	MHHES1	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	0.023371756588780768	[136]	[234,129,183,95]	0	hSpCas9	negative selection	7453231
407416	407439	11	+	27260156	MEWO	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.15852029830400394	[140]	[159,176,106]	3	hSpCas9	negative selection	7510226
407482	407505	11	-	27260156	MEWO	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.19528767398915914	[679]	[585,489,596]	-4	hSpCas9	negative selection	7510227
408694	408717	11	-	27260156	MEWO	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.021285671307457843	[268]	[306,287,180]	0	hSpCas9	negative selection	7510228
408687	408710	11	+	27260156	MEWO	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.23918712777106266	[855]	[764,694,591]	-5	hSpCas9	negative selection	7574480
407940	407963	11	-	27260156	MEWO	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.01341387065520791	[561]	[675,456,459]	0	hSpCas9	negative selection	7574481
407826	407849	11	+	27260156	MEWO	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	0.11781548293307909	[136]	[137,137,140]	2	hSpCas9	negative selection	7574482
407416	407439	11	+	27260156	LNCAPCLONEFGC	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.05876372008799269	[140]	[225,89,91,118]	0	hSpCas9	negative selection	7631477
407482	407505	11	-	27260156	LNCAPCLONEFGC	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.740517783545916	[679]	[316,310,514,357]	-8	hSpCas9	negative selection	7631478
408694	408717	11	-	27260156	LNCAPCLONEFGC	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.06642266535926411	[268]	[228,203,261,241]	-1	hSpCas9	negative selection	7631479
408687	408710	11	+	27260156	LNCAPCLONEFGC	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.27832579303355276	[855]	[621,550,637,751]	-4	hSpCas9	negative selection	7695731
407940	407963	11	-	27260156	LNCAPCLONEFGC	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.3863420630276013	[561]	[369,348,525,335]	-5	hSpCas9	negative selection	7695732
407826	407849	11	+	27260156	LNCAPCLONEFGC	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.2414055089909264	[136]	[80,153,90,88]	-4	hSpCas9	negative selection	7695733
407416	407439	11	+	27260156	PANC0327	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.9824486074304745	[140]	[97,482,143,221]	9	hSpCas9	negative selection	7752728
407482	407505	11	-	27260156	PANC0327	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.07704897525951504	[679]	[511,528,588,660]	-1	hSpCas9	negative selection	7752729
408694	408717	11	-	27260156	PANC0327	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.5518601646032155	[268]	[308,206,315,583]	7	hSpCas9	negative selection	7752730
408687	408710	11	+	27260156	PANC0327	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	0.3597179531516146	[855]	[1183,851,1122,776]	5	hSpCas9	negative selection	7816982
407940	407963	11	-	27260156	PANC0327	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.02431363356166502	[561]	[410,518,410,611]	0	hSpCas9	negative selection	7816983
407826	407849	11	+	27260156	PANC0327	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	0.29096999583610517	[136]	[136,51,156,260]	4	hSpCas9	negative selection	7816984
407416	407439	11	+	27260156	NCIH2009	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.19675294106419905	[140]	[244,267,166]	2	hSpCas9	negative selection	7873979
407482	407505	11	-	27260156	NCIH2009	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.026042374790530398	[679]	[983,843,1077]	0	hSpCas9	negative selection	7873980
408694	408717	11	-	27260156	NCIH2009	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.29371517717458395	[268]	[398,576,390]	4	hSpCas9	negative selection	7873981
408687	408710	11	+	27260156	NCIH2009	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	0.30884525201209767	[855]	[1561,1524,1369]	4	hSpCas9	negative selection	7938233
407940	407963	11	-	27260156	NCIH2009	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.23171507168907807	[561]	[1039,964,781]	3	hSpCas9	negative selection	7938234
407826	407849	11	+	27260156	NCIH2009	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	0.2840335357931465	[136]	[160,317,203]	4	hSpCas9	negative selection	7938235
407416	407439	11	+	27260156	NCIH1373	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	1.0906146425699836	[140]	[690,232,274,53]	9	hSpCas9	negative selection	7995230
407482	407505	11	-	27260156	NCIH1373	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.2999416173560462	[679]	[631,342,910,160]	-3	hSpCas9	negative selection	7995231
408694	408717	11	-	27260156	NCIH1373	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.32381221283049205	[268]	[576,445,195,81]	3	hSpCas9	negative selection	7995232
408687	408710	11	+	27260156	NCIH1373	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.3367506102385336	[855]	[645,435,926,277]	-3	hSpCas9	negative selection	8059484
407940	407963	11	-	27260156	NCIH1373	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.035867553451404105	[561]	[649,508,851,116]	0	hSpCas9	negative selection	8059485
407826	407849	11	+	27260156	NCIH1373	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.9714363856656456	[136]	[121,108,20,16]	-7	hSpCas9	negative selection	8059486
407416	407439	11	+	27260156	PATU8902	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	1.181443027189577	[140]	[625,150,440,572]	9	hSpCas9	negative selection	8116481
407482	407505	11	-	27260156	PATU8902	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.4909755287074509	[679]	[677,480,439,1215]	-5	hSpCas9	negative selection	8116482
408694	408717	11	-	27260156	PATU8902	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.6237154251087523	[268]	[466,626,483,775]	6	hSpCas9	negative selection	8116483
408687	408710	11	+	27260156	PATU8902	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.4569425732043804	[855]	[867,803,846,964]	-4	hSpCas9	negative selection	8180735
407940	407963	11	-	27260156	PATU8902	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.1466316599237838	[561]	[744,929,932,830]	1	hSpCas9	negative selection	8180736
407826	407849	11	+	27260156	PATU8902	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.8606425665233599	[136]	[178,130,20,109]	-7	hSpCas9	negative selection	8180737
407416	407439	11	+	27260156	PANC1	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.26131889734796765	[140]	[111,126,233,108]	4	hSpCas9	negative selection	8237732
407482	407505	11	-	27260156	PANC1	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.41318634736488796	[679]	[450,729,359,289]	-6	hSpCas9	negative selection	8237733
408694	408717	11	-	27260156	PANC1	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.2691777957149568	[268]	[196,324,102,168]	-4	hSpCas9	negative selection	8237734
408687	408710	11	+	27260156	PANC1	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.4515381640965449	[855]	[647,587,578,363]	-6	hSpCas9	negative selection	8301986
407940	407963	11	-	27260156	PANC1	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.12159860949462556	[561]	[327,438,566,436]	-2	hSpCas9	negative selection	8301987
407826	407849	11	+	27260156	PANC1	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.19295696736063683	[136]	[52,144,79,135]	-3	hSpCas9	negative selection	8301988
407416	407439	11	+	27260156	PANC0813	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.292160612908571	[140]	[207,254,195,154]	5	hSpCas9	negative selection	8358983
407482	407505	11	-	27260156	PANC0813	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.06258571638159477	[679]	[781,888,812,585]	-1	hSpCas9	negative selection	8358984
408694	408717	11	-	27260156	PANC0813	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.3440425356297843	[268]	[322,477,319,470]	5	hSpCas9	negative selection	8358985
408687	408710	11	+	27260156	PANC0813	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.5046259122428802	[855]	[691,712,886,549]	-6	hSpCas9	negative selection	8423237
407940	407963	11	-	27260156	PANC0813	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.31913150198351636	[561]	[766,1085,754,686]	5	hSpCas9	negative selection	8423238
407826	407849	11	+	27260156	PANC0813	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.1805419178388974	[136]	[165,223,98,83]	-3	hSpCas9	negative selection	8423239
407416	407439	11	+	27260156	RDES	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.22414262236617444	[140]	[173,220,125,234]	3	hSpCas9	negative selection	8480234
407482	407505	11	-	27260156	RDES	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.5033759698622297	[679]	[468,549,614,579]	-7	hSpCas9	negative selection	8480235
408694	408717	11	-	27260156	RDES	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.37255291338717345	[268]	[224,218,263,246]	-6	hSpCas9	negative selection	8480236
408687	408710	11	+	27260156	RDES	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.5272897838381159	[855]	[459,740,789,783]	-7	hSpCas9	negative selection	8544488
407940	407963	11	-	27260156	RDES	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.26072164000786424	[561]	[540,460,572,578]	-4	hSpCas9	negative selection	8544489
407826	407849	11	+	27260156	RDES	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.3944287318904387	[136]	[98,103,126,157]	-6	hSpCas9	negative selection	8544490
407416	407439	11	+	27260156	PC3	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	-0.01577311265979331	[140]	[62,134,204,204]	0	hSpCas9	negative selection	8601485
407482	407505	11	-	27260156	PC3	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.06290762962055951	[679]	[429,689,1114,815]	1	hSpCas9	negative selection	8601486
408694	408717	11	-	27260156	PC3	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.2330657899183617	[268]	[312,210,471,284]	5	hSpCas9	negative selection	8601487
408687	408710	11	+	27260156	PC3	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.18958544897238772	[855]	[519,579,1311,834]	-4	hSpCas9	negative selection	8665739
407940	407963	11	-	27260156	PC3	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.10769867970098174	[561]	[458,451,1127,581]	2	hSpCas9	negative selection	8665740
407826	407849	11	+	27260156	PC3	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.4004326415369823	[136]	[117,50,141,96]	-7	hSpCas9	negative selection	8665741
407416	407439	11	+	27260156	PATU8988T	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.6437227552148088	[140]	[161,240,195,258]	9	hSpCas9	negative selection	8722736
407482	407505	11	-	27260156	PATU8988T	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.2887856849044741	[679]	[598,506,553,483]	-5	hSpCas9	negative selection	8722737
408694	408717	11	-	27260156	PATU8988T	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.4224774117415695	[268]	[128,206,150,298]	-6	hSpCas9	negative selection	8722738
408687	408710	11	+	27260156	PATU8988T	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.05799998146493668	[855]	[1237,600,565,754]	-1	hSpCas9	negative selection	8786990
407940	407963	11	-	27260156	PATU8988T	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.19738055621735479	[561]	[674,653,607,550]	3	hSpCas9	negative selection	8786991
407826	407849	11	+	27260156	PATU8988T	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	0.06168692301837364	[136]	[103,195,83,177]	1	hSpCas9	negative selection	8786992
407416	407439	11	+	27260156	T47D	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.6663588220849614	[140]	[389,215,229,209]	9	hSpCas9	negative selection	8843987
407482	407505	11	-	27260156	T47D	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.14753700672133646	[679]	[852,657,685,667]	-3	hSpCas9	negative selection	8843988
408694	408717	11	-	27260156	T47D	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.06395192542750794	[268]	[315,270,322,290]	-1	hSpCas9	negative selection	8843989
408687	408710	11	+	27260156	T47D	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.2641699291506414	[855]	[832,778,838,875]	-5	hSpCas9	negative selection	8908241
407940	407963	11	-	27260156	T47D	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.19537264070900567	[561]	[733,624,773,879]	4	hSpCas9	negative selection	8908242
407826	407849	11	+	27260156	T47D	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.4254948373642822	[136]	[116,89,116,154]	-7	hSpCas9	negative selection	8908243
407416	407439	11	+	27260156	SU8686	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.11073611193069888	[140]	[99,130,164,227]	1	hSpCas9	negative selection	8965238
407482	407505	11	-	27260156	SU8686	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.11851119660012155	[679]	[720,618,688,941]	2	hSpCas9	negative selection	8965239
408694	408717	11	-	27260156	SU8686	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.06382621932867427	[268]	[213,248,249,435]	1	hSpCas9	negative selection	8965240
408687	408710	11	+	27260156	SU8686	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.25970188967484975	[855]	[654,455,816,989]	-4	hSpCas9	negative selection	9029492
407940	407963	11	-	27260156	SU8686	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.07077569543146756	[561]	[467,580,469,610]	-1	hSpCas9	negative selection	9029493
407826	407849	11	+	27260156	SU8686	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.29312392667514	[136]	[63,143,118,117]	-5	hSpCas9	negative selection	9029494
407416	407439	11	+	27260156	SKES1	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.3502180166694011	[140]	[171,265,111,175]	7	hSpCas9	negative selection	9086489
407482	407505	11	-	27260156	SKES1	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.20219205976026983	[679]	[675,584,465,632]	-4	hSpCas9	negative selection	9086490
408694	408717	11	-	27260156	SKES1	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.3052034521499627	[268]	[251,185,206,221]	-6	hSpCas9	negative selection	9086491
408687	408710	11	+	27260156	SKES1	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.31084965161417544	[855]	[903,883,499,532]	-6	hSpCas9	negative selection	9150743
407940	407963	11	-	27260156	SKES1	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.26356666334737444	[561]	[751,736,738,495]	5	hSpCas9	negative selection	9150744
407826	407849	11	+	27260156	SKES1	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.28523448307428656	[136]	[168,101,85,98]	-6	hSpCas9	negative selection	9150745
407416	407439	11	+	27260156	TOV112D	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.5615892431053042	[140]	[356,198,131,156]	8	hSpCas9	negative selection	9207740
407482	407505	11	-	27260156	TOV112D	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.23051956909057558	[679]	[571,853,396,564]	-4	hSpCas9	negative selection	9207741
408694	408717	11	-	27260156	TOV112D	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	-0.47525149939150624	[268]	[235,188,148,202]	-7	hSpCas9	negative selection	9207742
408687	408710	11	+	27260156	TOV112D	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.1547677597087107	[855]	[1220,805,582,522]	-3	hSpCas9	negative selection	9271994
407940	407963	11	-	27260156	TOV112D	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.07103778217061352	[561]	[438,687,482,560]	-1	hSpCas9	negative selection	9271995
407826	407849	11	+	27260156	TOV112D	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.07325350619315096	[136]	[175,240,58,77]	-1	hSpCas9	negative selection	9271996
407416	407439	11	+	27260156	TC71	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.23129606348855059	[140]	[256,159,104,188]	6	hSpCas9	negative selection	9328991
407482	407505	11	-	27260156	TC71	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.0768417349684708	[679]	[687,667,662,749]	-2	hSpCas9	negative selection	9328992
408694	408717	11	-	27260156	TC71	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.05246784342917277	[268]	[318,327,322,219]	1	hSpCas9	negative selection	9328993
408687	408710	11	+	27260156	TC71	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.4342056457408195	[855]	[729,749,600,633]	-8	hSpCas9	negative selection	9393245
407940	407963	11	-	27260156	TC71	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.04048286347727825	[561]	[726,609,482,662]	1	hSpCas9	negative selection	9393246
407826	407849	11	+	27260156	TC71	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	-0.20336110794547735	[136]	[118,127,76,191]	-5	hSpCas9	negative selection	9393247
407416	407439	11	+	27260156	TC32	viability	CCGGGATACCAGCGCGCGGCAGG	SIGIRR	ENSG00000185187	0.4545985196437663	[140]	[203,135,213,180]	7	hSpCas9	negative selection	9450242
407482	407505	11	-	27260156	TC32	viability	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.16655878533336477	[679]	[546,474,628,643]	-3	hSpCas9	negative selection	9450243
408694	408717	11	-	27260156	TC32	viability	ACAGCCTCCACGAGTACTCCTGG	SIGIRR	ENSG00000185187	0.056223219752615794	[268]	[167,312,334,220]	1	hSpCas9	negative selection	9450244
408687	408710	11	+	27260156	TC32	viability	TCTCTTACCAGGAGTACTCGTGG	SIGIRR	ENSG00000185187	-0.20878951948425029	[855]	[622,563,877,771]	-4	hSpCas9	negative selection	9514496
407940	407963	11	-	27260156	TC32	viability	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	-0.07373632459957724	[561]	[588,264,550,669]	-1	hSpCas9	negative selection	9514497
407826	407849	11	+	27260156	TC32	viability	CCACCTCCCCATACGCGTCCTGG	SIGIRR	ENSG00000185187	0.1322737254956563	[136]	[134,93,175,177]	2	hSpCas9	negative selection	9514498
406857	406880	11	+	27869803	HPAFII	viability after 27 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.21832654133146345	[124]	[148,15,NaN]	1	hSpCas9	negative selection	9541447
407061	407084	11	+	27869803	HPAFII	viability after 27 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.4419142955205927	[376]	[206,94,NaN]	-3	hSpCas9	negative selection	9541448
407482	407505	11	-	27869803	HPAFII	viability after 27 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.3467397590046052	[167]	[33,98,NaN]	-3	hSpCas9	negative selection	9541449
407940	407963	11	-	27869803	HPAFII	viability after 27 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.48522234909734774	[797]	[889,334,NaN]	4	hSpCas9	negative selection	9541451
408101	408124	11	+	27869803	HPAFII	viability after 27 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.03374705376974152	[173]	[168,22,NaN]	0	hSpCas9	negative selection	9541453
408841	408864	11	+	27869803	HPAFII	viability after 27 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.03443970040521016	[1703]	[913,841,NaN]	0	hSpCas9	negative selection	9541454
406857	406880	11	+	27869803	HPAFII	viability after 15 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.8338358952895597	[124]	[437,115,NaN]	8	hSpCas9	negative selection	9623896
407061	407084	11	+	27869803	HPAFII	viability after 15 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.42783565504952825	[376]	[434,217,NaN]	-5	hSpCas9	negative selection	9623897
407482	407505	11	-	27869803	HPAFII	viability after 15 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.9126308097409339	[167]	[61,116,NaN]	-7	hSpCas9	negative selection	9623898
407940	407963	11	-	27869803	HPAFII	viability after 15 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.32175107886759147	[797]	[1542,778,NaN]	3	hSpCas9	negative selection	9623900
408101	408124	11	+	27869803	HPAFII	viability after 15 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.5658598696051246	[173]	[269,36,NaN]	-6	hSpCas9	negative selection	9623902
408841	408864	11	+	27869803	HPAFII	viability after 15 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	0.005316192519256635	[1703]	[2019,1724,NaN]	0	hSpCas9	negative selection	9623903
406857	406880	11	+	27869803	ASPC1	viability after 36 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	0.2891179189240149	[388]	[14,199,242]	3	hSpCas9	negative selection	9706345
407061	407084	11	+	27869803	ASPC1	viability after 36 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.00603855353671956	[827]	[804,118,55]	0	hSpCas9	negative selection	9706346
407482	407505	11	-	27869803	ASPC1	viability after 36 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.3216396094324271	[578]	[141,285,300]	3	hSpCas9	negative selection	9706347
407940	407963	11	-	27869803	ASPC1	viability after 36 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.9351334459639236	[1896]	[2178,1238,633]	8	hSpCas9	negative selection	9706349
408101	408124	11	+	27869803	ASPC1	viability after 36 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.15334778571577723	[415]	[83,239,74]	-1	hSpCas9	negative selection	9706351
408841	408864	11	+	27869803	ASPC1	viability after 36 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.4727239184321599	[5145]	[1764,1608,700]	-5	hSpCas9	negative selection	9706352
406857	406880	11	+	27869803	PATU8988S	viability after 35 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	-0.16935155266077095	[284]	[132,70,NaN]	-2	hSpCas9	negative selection	9788794
407061	407084	11	+	27869803	PATU8988S	viability after 35 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.21363570778818683	[726]	[251,252,NaN]	-2	hSpCas9	negative selection	9788795
407482	407505	11	-	27869803	PATU8988S	viability after 35 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.2870644349269791	[410]	[189,213,NaN]	3	hSpCas9	negative selection	9788796
407940	407963	11	-	27869803	PATU8988S	viability after 35 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.2720579061589461	[1671]	[877,747,NaN]	3	hSpCas9	negative selection	9788798
408101	408124	11	+	27869803	PATU8988S	viability after 35 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.010378351241046468	[349]	[118,160,NaN]	0	hSpCas9	negative selection	9788800
408841	408864	11	+	27869803	PATU8988S	viability after 35 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.5711003381318749	[4066]	[897,1307,NaN]	-5	hSpCas9	negative selection	9788801
406857	406880	11	+	27869803	PATU8988S	viability after 31 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	-0.17244097892075017	[284]	[95,106,NaN]	-2	hSpCas9	negative selection	9871243
407061	407084	11	+	27869803	PATU8988S	viability after 31 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	0.17536229563966405	[726]	[296,365,NaN]	2	hSpCas9	negative selection	9871244
407482	407505	11	-	27869803	PATU8988S	viability after 31 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.27678261160296064	[410]	[107,169,NaN]	-3	hSpCas9	negative selection	9871245
407940	407963	11	-	27869803	PATU8988S	viability after 31 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.02564812315673981	[1671]	[569,816,NaN]	0	hSpCas9	negative selection	9871247
408101	408124	11	+	27869803	PATU8988S	viability after 31 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.14479221854498658	[349]	[94,165,NaN]	-2	hSpCas9	negative selection	9871249
408841	408864	11	+	27869803	PATU8988S	viability after 31 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	-0.491594661108282	[4066]	[998,1349,NaN]	-5	hSpCas9	negative selection	9871250
406857	406880	11	+	27869803	HPAFII	viability after 35 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	-0.18522713233710464	[124]	[73,34,NaN]	-1	hSpCas9	negative selection	9953692
407061	407084	11	+	27869803	HPAFII	viability after 35 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.6225497896462386	[376]	[170,70,NaN]	-4	hSpCas9	negative selection	9953693
407482	407505	11	-	27869803	HPAFII	viability after 35 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	0.1083037812608032	[167]	[38,150,NaN]	0	hSpCas9	negative selection	9953694
407940	407963	11	-	27869803	HPAFII	viability after 35 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.29301312811264557	[797]	[652,316,NaN]	1	hSpCas9	negative selection	9953696
408101	408124	11	+	27869803	HPAFII	viability after 35 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.07793592766717194	[173]	[163,12,NaN]	0	hSpCas9	negative selection	9953698
408841	408864	11	+	27869803	HPAFII	viability after 35 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	0.2087485518002179	[1703]	[765,1256,NaN]	1	hSpCas9	negative selection	9953699
406857	406880	11	+	27869803	HPAFII	viability after 31 days	TCCAGAGCAGCAAGGTCACCAGG	SIGIRR	ENSG00000185187	-0.10592916348614301	[124]	[113,11,NaN]	0	hSpCas9	negative selection	10036141
407061	407084	11	+	27869803	HPAFII	viability after 31 days	CCGGAAGCTGTGGCTGCACCAGG	SIGIRR	ENSG00000185187	-0.33211883042671314	[376]	[191,141,NaN]	-2	hSpCas9	negative selection	10036142
407482	407505	11	-	27869803	HPAFII	viability after 31 days	CTTCATCCTAAAGCCGCAGCTGG	SIGIRR	ENSG00000185187	-0.09192299191474351	[167]	[42,137,NaN]	0	hSpCas9	negative selection	10036143
407940	407963	11	-	27869803	HPAFII	viability after 31 days	CGCAGGCCCTACAAGCCACGTGG	SIGIRR	ENSG00000185187	0.35876907131817815	[797]	[725,408,NaN]	2	hSpCas9	negative selection	10036145
408101	408124	11	+	27869803	HPAFII	viability after 31 days	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.28751539497908196	[173]	[135,18,NaN]	-2	hSpCas9	negative selection	10036147
408841	408864	11	+	27869803	HPAFII	viability after 31 days	CAGCACCTGGTCTTCAGACGGGG	SIGIRR	ENSG00000185187	0.13308719662683455	[1703]	[930,1176,NaN]	0	hSpCas9	negative selection	10036148
408759	408782	11	+	28162770	P31FUJ	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-1.4897105074513308	[281]	[117]	-7	hSpCas9	negative selection	10234174
406433	406456	11	-	28162770	P31FUJ	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.20509940321620224	[312]	[423]	2	hSpCas9	negative selection	10234175
408101	408124	11	+	28162770	P31FUJ	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.00820589508941616	[65]	[77]	0	hSpCas9	negative selection	10234176
407901	407924	11	+	28162770	P31FUJ	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-1.4403976238227458	[96]	[41]	-7	hSpCas9	negative selection	10234177
407829	407852	11	-	28162770	P31FUJ	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.09734639727795197	[244]	[307]	1	hSpCas9	negative selection	10234178
407528	407551	11	+	28162770	P31FUJ	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	-0.11426258923897747	[361]	[392]	-1	hSpCas9	negative selection	10234179
407139	407162	11	+	28162770	P31FUJ	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	-0.2813007221055687	[241]	[233]	-3	hSpCas9	negative selection	10234180
407051	407074	11	+	28162770	P31FUJ	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	-0.5150660817282251	[286]	[235]	-4	hSpCas9	negative selection	10234181
406863	406886	11	+	28162770	P31FUJ	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	-0.022303461659184176	[521]	[603]	0	hSpCas9	negative selection	10234182
407872	407895	11	+	28162770	P31FUJ	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	-0.12177089202563462	[174]	[188]	-1	hSpCas9	negative selection	10234183
408759	408782	11	+	28162770	TF1	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10403540
406433	406456	11	-	28162770	TF1	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10403541
408101	408124	11	+	28162770	TF1	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	NaN	[NaN]	[78]	1	hSpCas9	negative selection	10403542
407901	407924	11	+	28162770	TF1	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10403543
407829	407852	11	-	28162770	TF1	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	NaN	[NaN]	[226]	1	hSpCas9	negative selection	10403544
407528	407551	11	+	28162770	TF1	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	NaN	[NaN]	[168]	1	hSpCas9	negative selection	10403545
407139	407162	11	+	28162770	TF1	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10403546
407051	407074	11	+	28162770	TF1	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	NaN	[NaN]	[347]	1	hSpCas9	negative selection	10403547
406863	406886	11	+	28162770	TF1	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	NaN	[NaN]	[316]	1	hSpCas9	negative selection	10403548
407872	407895	11	+	28162770	TF1	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10403549
408759	408782	11	+	28162770	SKM1	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-3.023635559191656	[114]	[24]	-9	hSpCas9	negative selection	10572906
406433	406456	11	-	28162770	SKM1	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.7223188182018045	[71]	[209]	7	hSpCas9	negative selection	10572907
408101	408124	11	+	28162770	SKM1	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.42607302169086636	[18]	[24]	-4	hSpCas9	negative selection	10572908
407901	407924	11	+	28162770	SKM1	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-1.5589672921882116	[14]	[8]	-8	hSpCas9	negative selection	10572909
407829	407852	11	-	28162770	SKM1	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.05815853197199128	[68]	[126]	0	hSpCas9	negative selection	10572910
407528	407551	11	+	28162770	SKM1	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	0.35384813737741205	[107]	[243]	3	hSpCas9	negative selection	10572911
407139	407162	11	+	28162770	SKM1	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	-0.4831997845702467	[33]	[42]	-4	hSpCas9	negative selection	10572912
407051	407074	11	+	28162770	SKM1	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	0.7841772886088465	[44]	[136]	7	hSpCas9	negative selection	10572913
406863	406886	11	+	28162770	SKM1	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	0.4283216560622345	[94]	[225]	4	hSpCas9	negative selection	10572914
407872	407895	11	+	28162770	SKM1	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.5684577785361724	[36]	[96]	5	hSpCas9	negative selection	10572915
408759	408782	11	+	28162770	SKM1	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-3.023635559191656	[114]	[24]	-9	hSpCas9	negative selection	10742272
406433	406456	11	-	28162770	SKM1	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.7223188182018045	[71]	[209]	7	hSpCas9	negative selection	10742273
408101	408124	11	+	28162770	SKM1	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.42607302169086636	[18]	[24]	-4	hSpCas9	negative selection	10742274
407901	407924	11	+	28162770	SKM1	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-1.5589672921882116	[14]	[8]	-8	hSpCas9	negative selection	10742275
407829	407852	11	-	28162770	SKM1	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.05815853197199128	[68]	[126]	0	hSpCas9	negative selection	10742276
407528	407551	11	+	28162770	SKM1	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	0.35384813737741205	[107]	[243]	3	hSpCas9	negative selection	10742277
407139	407162	11	+	28162770	SKM1	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	-0.4831997845702467	[33]	[42]	-4	hSpCas9	negative selection	10742278
407051	407074	11	+	28162770	SKM1	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	0.7841772886088465	[44]	[136]	7	hSpCas9	negative selection	10742279
406863	406886	11	+	28162770	SKM1	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	0.4283216560622345	[94]	[225]	4	hSpCas9	negative selection	10742280
407872	407895	11	+	28162770	SKM1	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.5684577785361724	[36]	[96]	5	hSpCas9	negative selection	10742281
408759	408782	11	+	28162770	PL21	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-1.1002553188484008	[265]	[53]	-6	hSpCas9	negative selection	10911638
406433	406456	11	-	28162770	PL21	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.3676937114688857	[202]	[113]	3	hSpCas9	negative selection	10911639
408101	408124	11	+	28162770	PL21	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.24195979018394742	[67]	[34]	2	hSpCas9	negative selection	10911640
407901	407924	11	+	28162770	PL21	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-1.9697853869529922	[71]	[7]	-8	hSpCas9	negative selection	10911641
407829	407852	11	-	28162770	PL21	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.2373725206882954	[305]	[156]	2	hSpCas9	negative selection	10911642
407528	407551	11	+	28162770	PL21	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	-0.46459016302917444	[408]	[128]	-3	hSpCas9	negative selection	10911643
407139	407162	11	+	28162770	PL21	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	0.311170926878064	[149]	[80]	2	hSpCas9	negative selection	10911644
407051	407074	11	+	28162770	PL21	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	-0.793518858636853	[226]	[56]	-5	hSpCas9	negative selection	10911645
406863	406886	11	+	28162770	PL21	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	-0.2998252332239991	[378]	[133]	-2	hSpCas9	negative selection	10911646
407872	407895	11	+	28162770	PL21	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	1.096516983415163	[100]	[93]	8	hSpCas9	negative selection	10911647
408759	408782	11	+	28162770	P31FUJ	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-1.4897105074513308	[281]	[117]	-7	hSpCas9	negative selection	11081004
406433	406456	11	-	28162770	P31FUJ	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.20509940321620224	[312]	[423]	2	hSpCas9	negative selection	11081005
408101	408124	11	+	28162770	P31FUJ	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.00820589508941616	[65]	[77]	0	hSpCas9	negative selection	11081006
407901	407924	11	+	28162770	P31FUJ	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-1.4403976238227458	[96]	[41]	-7	hSpCas9	negative selection	11081007
407829	407852	11	-	28162770	P31FUJ	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.09734639727795197	[244]	[307]	1	hSpCas9	negative selection	11081008
407528	407551	11	+	28162770	P31FUJ	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	-0.11426258923897747	[361]	[392]	-1	hSpCas9	negative selection	11081009
407139	407162	11	+	28162770	P31FUJ	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	-0.2813007221055687	[241]	[233]	-3	hSpCas9	negative selection	11081010
407051	407074	11	+	28162770	P31FUJ	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	-0.5150660817282251	[286]	[235]	-4	hSpCas9	negative selection	11081011
406863	406886	11	+	28162770	P31FUJ	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	-0.022303461659184176	[521]	[603]	0	hSpCas9	negative selection	11081012
407872	407895	11	+	28162770	P31FUJ	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	-0.12177089202563462	[174]	[188]	-1	hSpCas9	negative selection	11081013
408759	408782	11	+	28162770	OCIAML5	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-4.115100976697791	[143]	[14]	-9	hSpCas9	negative selection	11250370
406433	406456	11	-	28162770	OCIAML5	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.13459562959885019	[162]	[322]	1	hSpCas9	negative selection	11250371
408101	408124	11	+	28162770	OCIAML5	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-1.977597452947856	[23]	[10]	-8	hSpCas9	negative selection	11250372
407901	407924	11	+	28162770	OCIAML5	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-2.9895700946139314	[43]	[9]	-8	hSpCas9	negative selection	11250373
407829	407852	11	-	28162770	OCIAML5	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.4810597306282293	[153]	[387]	4	hSpCas9	negative selection	11250374
407528	407551	11	+	28162770	OCIAML5	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	-0.3645165718007853	[193]	[271]	-3	hSpCas9	negative selection	11250375
407139	407162	11	+	28162770	OCIAML5	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	-0.45447420604456246	[103]	[136]	-3	hSpCas9	negative selection	11250376
407051	407074	11	+	28162770	OCIAML5	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	-0.3777898682104772	[166]	[231]	-3	hSpCas9	negative selection	11250377
406863	406886	11	+	28162770	OCIAML5	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	0.44821296071860206	[187]	[462]	4	hSpCas9	negative selection	11250378
407872	407895	11	+	28162770	OCIAML5	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	-0.47019593552035255	[98]	[128]	-3	hSpCas9	negative selection	11250379
408759	408782	11	+	28162770	EOL1	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-2.359660657367669	[603]	[61]	-8	hSpCas9	negative selection	11419736
406433	406456	11	-	28162770	EOL1	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.4792372611778901	[304]	[223]	4	hSpCas9	negative selection	11419737
408101	408124	11	+	28162770	EOL1	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.1841915882035543	[141]	[84]	1	hSpCas9	negative selection	11419738
407901	407924	11	+	28162770	EOL1	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-1.297844649765913	[167]	[35]	-7	hSpCas9	negative selection	11419739
407829	407852	11	-	28162770	EOL1	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.22734400627970064	[500]	[308]	2	hSpCas9	negative selection	11419740
407528	407551	11	+	28162770	EOL1	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	-0.056406472738918856	[601]	[304]	0	hSpCas9	negative selection	11419741
407139	407162	11	+	28162770	EOL1	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	-0.06177729153238898	[209]	[105]	0	hSpCas9	negative selection	11419742
407051	407074	11	+	28162770	EOL1	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	-1.5454789623059617	[204]	[36]	-7	hSpCas9	negative selection	11419743
406863	406886	11	+	28162770	EOL1	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	0.5973830283170252	[482]	[384]	5	hSpCas9	negative selection	11419744
407872	407895	11	+	28162770	EOL1	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.8519440226136944	[162]	[154]	7	hSpCas9	negative selection	11419745
408759	408782	11	+	28162770	MOLM13	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-3.0118010760765186	[501]	[44]	-8	hSpCas9	negative selection	11589102
406433	406456	11	-	28162770	MOLM13	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	-0.6590227309376407	[379]	[173]	-4	hSpCas9	negative selection	11589103
408101	408124	11	+	28162770	MOLM13	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.9807020965098998	[81]	[116]	7	hSpCas9	negative selection	11589104
407901	407924	11	+	28162770	MOLM13	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-0.5922316108929921	[97]	[46]	-3	hSpCas9	negative selection	11589105
407829	407852	11	-	28162770	MOLM13	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.9268574836988882	[282]	[388]	7	hSpCas9	negative selection	11589106
407528	407551	11	+	28162770	MOLM13	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	1.3924371531151134	[470]	[893]	9	hSpCas9	negative selection	11589107
407139	407162	11	+	28162770	MOLM13	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	0.207574477064377	[211]	[176]	1	hSpCas9	negative selection	11589108
407051	407074	11	+	28162770	MOLM13	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	-0.1170731191765772	[224]	[149]	0	hSpCas9	negative selection	11589109
406863	406886	11	+	28162770	MOLM13	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	0.8315446020416646	[442]	[569]	6	hSpCas9	negative selection	11589110
407872	407895	11	+	28162770	MOLM13	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	-2.1881562172380598	[207]	[32]	-7	hSpCas9	negative selection	11589111
408759	408782	11	+	28162770	HEL	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-2.422031423389881	[409]	[48]	-8	hSpCas9	negative selection	11758468
406433	406456	11	-	28162770	HEL	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	-0.336941183620047	[281]	[142]	-2	hSpCas9	negative selection	11758469
408101	408124	11	+	28162770	HEL	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-0.5008520216284931	[94]	[42]	-3	hSpCas9	negative selection	11758470
407901	407924	11	+	28162770	HEL	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-1.0202261807220727	[94]	[29]	-6	hSpCas9	negative selection	11758471
407829	407852	11	-	28162770	HEL	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.1442163472184318	[331]	[234]	1	hSpCas9	negative selection	11758472
407528	407551	11	+	28162770	HEL	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	0.7967304785388608	[434]	[483]	7	hSpCas9	negative selection	11758473
407139	407162	11	+	28162770	HEL	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	0.24486188387969607	[194]	[147]	2	hSpCas9	negative selection	11758474
407051	407074	11	+	28162770	HEL	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	1.287822325159084	[187]	[293]	9	hSpCas9	negative selection	11758475
406863	406886	11	+	28162770	HEL	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	0.25759090464043877	[413]	[316]	2	hSpCas9	negative selection	11758476
407872	407895	11	+	28162770	HEL	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.06236360077485259	[156]	[104]	0	hSpCas9	negative selection	11758477
408759	408782	11	+	28162770	MV411	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-2.8579154493634533	[283]	[32]	-9	hSpCas9	negative selection	11927834
406433	406456	11	-	28162770	MV411	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.3633568380823428	[250]	[271]	3	hSpCas9	negative selection	11927835
408101	408124	11	+	28162770	MV411	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-2.489528043383431	[59]	[8]	-8	hSpCas9	negative selection	11927836
407901	407924	11	+	28162770	MV411	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	0.7499378913119584	[59]	[84]	6	hSpCas9	negative selection	11927837
407829	407852	11	-	28162770	MV411	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	-0.8123436775426416	[270]	[129]	-5	hSpCas9	negative selection	11927838
407528	407551	11	+	28162770	MV411	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	-0.16319476937606736	[326]	[245]	-1	hSpCas9	negative selection	11927839
407139	407162	11	+	28162770	MV411	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	-0.5003754256204233	[177]	[105]	-4	hSpCas9	negative selection	11927840
407051	407074	11	+	28162770	MV411	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	0.21995681436066822	[158]	[155]	2	hSpCas9	negative selection	11927841
406863	406886	11	+	28162770	MV411	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	0.3447347521376902	[300]	[321]	3	hSpCas9	negative selection	11927842
407872	407895	11	+	28162770	MV411	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	0.39427893911204637	[111]	[123]	3	hSpCas9	negative selection	11927843
408759	408782	11	+	28162770	MONOMAC1	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-3.0630194990878663	[225]	[30]	-9	hSpCas9	negative selection	12097200
406433	406456	11	-	28162770	MONOMAC1	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.838882727195389	[118]	[243]	7	hSpCas9	negative selection	12097201
408101	408124	11	+	28162770	MONOMAC1	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	-1.8215277119673476	[36]	[11]	-8	hSpCas9	negative selection	12097202
407901	407924	11	+	28162770	MONOMAC1	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-0.2547523449158411	[50]	[48]	-2	hSpCas9	negative selection	12097203
407829	407852	11	-	28162770	MONOMAC1	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	-0.1089806703943576	[142]	[151]	-1	hSpCas9	negative selection	12097204
407528	407551	11	+	28162770	MONOMAC1	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	-1.268119945121036	[207]	[98]	-7	hSpCas9	negative selection	12097205
407139	407162	11	+	28162770	MONOMAC1	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	0.10877158246453189	[71]	[88]	1	hSpCas9	negative selection	12097206
407051	407074	11	+	28162770	MONOMAC1	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	1.738514445213604	[102]	[393]	9	hSpCas9	negative selection	12097207
406863	406886	11	+	28162770	MONOMAC1	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	0.008432271240425893	[195]	[225]	0	hSpCas9	negative selection	12097208
407872	407895	11	+	28162770	MONOMAC1	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	-0.46712601042729784	[81]	[67]	-4	hSpCas9	negative selection	12097209
408759	408782	11	+	28162770	OCIAML2	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-2.620007449280388	[60]	[54]	-8	hSpCas9	negative selection	12266566
406433	406456	11	-	28162770	OCIAML2	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	-0.04253617313787117	[54]	[295]	0	hSpCas9	negative selection	12266567
408101	408124	11	+	28162770	OCIAML2	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	1.1616383902573517	[9]	[123]	9	hSpCas9	negative selection	12266568
407901	407924	11	+	28162770	OCIAML2	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-2.3007048237998484	[15]	[17]	-8	hSpCas9	negative selection	12266569
407829	407852	11	-	28162770	OCIAML2	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.23918416266407805	[58]	[385]	2	hSpCas9	negative selection	12266570
407528	407551	11	+	28162770	OCIAML2	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	0.9295177119590232	[69]	[738]	8	hSpCas9	negative selection	12266571
407139	407162	11	+	28162770	OCIAML2	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	0.46348223910138164	[27]	[213]	4	hSpCas9	negative selection	12266572
407051	407074	11	+	28162770	OCIAML2	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	-0.2802986131380119	[38]	[177]	-2	hSpCas9	negative selection	12266573
406863	406886	11	+	28162770	OCIAML2	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	-0.2216022774022467	[68]	[327]	-2	hSpCas9	negative selection	12266574
407872	407895	11	+	28162770	OCIAML2	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	-0.458246100786329	[28]	[116]	-4	hSpCas9	negative selection	12266575
408759	408782	11	+	28162770	OCIAML3	viability	GGACTGAAGGCAGGGAGCAGTGG	SIGIRR	ENSG00000185187	-1.7118441306180214	[101]	[93]	-8	hSpCas9	negative selection	12435932
406433	406456	11	-	28162770	OCIAML3	viability	GACGCAGCTGCAGGACGACAAGG	SIGIRR	ENSG00000185187	0.4808795713068287	[60]	[256]	4	hSpCas9	negative selection	12435933
408101	408124	11	+	28162770	OCIAML3	viability	GCTGATGTTCTGGATGGAGCAGG	SIGIRR	ENSG00000185187	0.6913945785380853	[7]	[38]	6	hSpCas9	negative selection	12435934
407901	407924	11	+	28162770	OCIAML3	viability	GCAGGGCCAGCAGGACCAGGAGG	SIGIRR	ENSG00000185187	-0.9241562420164939	[21]	[34]	-6	hSpCas9	negative selection	12435935
407829	407852	11	-	28162770	OCIAML3	viability	GTACCAGGACGCGTATGGGGAGG	SIGIRR	ENSG00000185187	0.7735014888720947	[80]	[417]	7	hSpCas9	negative selection	12435936
407528	407551	11	+	28162770	OCIAML3	viability	GCAGTCGCTGTAGGAGACGTAGG	SIGIRR	ENSG00000185187	0.3305849570178143	[107]	[409]	3	hSpCas9	negative selection	12435937
407139	407162	11	+	28162770	OCIAML3	viability	GTTCACCAAGAGGTCGGCGGAGG	SIGIRR	ENSG00000185187	-0.6094376808937692	[46]	[92]	-5	hSpCas9	negative selection	12435938
407051	407074	11	+	28162770	OCIAML3	viability	GCGGGACCCACCGGAAGCTGTGG	SIGIRR	ENSG00000185187	-0.1910429733458944	[44]	[118]	-1	hSpCas9	negative selection	12435939
406863	406886	11	+	28162770	OCIAML3	viability	GCAGCAAGGTCACCAGGTGGCGG	SIGIRR	ENSG00000185187	0.2804614775919779	[83]	[307]	2	hSpCas9	negative selection	12435940
407872	407895	11	+	28162770	OCIAML3	viability	GCACTTGACATAGAGCAGGGCGG	SIGIRR	ENSG00000185187	1.7679361334110784	[31]	[328]	9	hSpCas9	negative selection	12435941