Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:23309
• Symbol:SIN3B
• Description:SIN3 transcription regulator family member B

DataSource: http://genomecrispr.dkfz.de/#!/results/SIN3B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
16829418	16829441	19	+	26472758	Jiyoye	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.1998134255452817	[98]	[64]	-1	hSpCas9	negative selection	146936
16862958	16862981	19	+	26472758	Jiyoye	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-1.171445592341456	[226]	[75]	-7	hSpCas9	negative selection	146937
16829876	16829899	19	+	26472758	Jiyoye	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	2.0372257717555677	[20]	[64]	8	hSpCas9	negative selection	146938
16841767	16841790	19	+	26472758	Jiyoye	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.7080418608654062	[137]	[169]	5	hSpCas9	negative selection	146939
16841821	16841844	19	+	26472758	Jiyoye	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.9514958977296837	[71]	[104]	6	hSpCas9	negative selection	146940
16846969	16846992	19	+	26472758	Jiyoye	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-1.0257840257702329	[107]	[39]	-6	hSpCas9	negative selection	146941
16847033	16847056	19	+	26472758	Jiyoye	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	1.4286551089163249	[99]	[202]	8	hSpCas9	negative selection	146942
16851499	16851522	19	-	26472758	Jiyoye	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	-0.30004286926628054	[79]	[48]	-2	hSpCas9	negative selection	146943
16853103	16853126	19	-	26472758	Jiyoye	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.24409646426304898	[255]	[162]	-2	hSpCas9	negative selection	146944
16854145	16854168	19	-	26472758	Jiyoye	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	0.959716404534652	[44]	[65]	6	hSpCas9	negative selection	146945
16829418	16829441	19	+	26472758	KBM7	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	1.0289129720260375	[547,274]	[414,354]	9	hSpCas9	negative selection	338054
16862958	16862981	19	+	26472758	KBM7	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	0.2997490008616932	[759,634]	[534,282]	3	hSpCas9	negative selection	338055
16829876	16829899	19	+	26472758	KBM7	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	0.8490597374239537	[295,200]	[237,179]	8	hSpCas9	negative selection	338056
16841767	16841790	19	+	26472758	KBM7	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.7841579557204585	[751,452]	[546,415]	8	hSpCas9	negative selection	338057
16841821	16841844	19	+	26472758	KBM7	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.4229780891159126	[457,255]	[254,187]	4	hSpCas9	negative selection	338058
16846969	16846992	19	+	26472758	KBM7	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	0.43716875581518744	[330,257]	[298,84]	5	hSpCas9	negative selection	338059
16847033	16847056	19	+	26472758	KBM7	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.5591072345183609	[790,641]	[436,543]	6	hSpCas9	negative selection	338060
16851499	16851522	19	-	26472758	KBM7	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	0.5379012680057036	[305,226]	[112,239]	6	hSpCas9	negative selection	338061
16853103	16853126	19	-	26472758	KBM7	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	0.002026566224599735	[985,1006]	[509,437]	0	hSpCas9	negative selection	338062
16854145	16854168	19	-	26472758	KBM7	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	0.06864038799325689	[295,230]	[186,76]	0	hSpCas9	negative selection	338063
16829418	16829441	19	+	26472758	Raji	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.8374749104339394	[153]	[19]	-6	hSpCas9	negative selection	529172
16862958	16862981	19	+	26472758	Raji	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.22242815858959586	[366]	[72]	-2	hSpCas9	negative selection	529173
16829876	16829899	19	+	26472758	Raji	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	0.46527712754883443	[102]	[32]	4	hSpCas9	negative selection	529174
16841767	16841790	19	+	26472758	Raji	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.5793627033048715	[366]	[56]	-4	hSpCas9	negative selection	529175
16841821	16841844	19	+	26472758	Raji	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.747713346494686	[212]	[82]	7	hSpCas9	negative selection	529176
16846969	16846992	19	+	26472758	Raji	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-1.1620771396196274	[134]	[13]	-7	hSpCas9	negative selection	529177
16847033	16847056	19	+	26472758	Raji	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	-0.4023726211583828	[597]	[104]	-3	hSpCas9	negative selection	529178
16851499	16851522	19	-	26472758	Raji	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	-1.1780186834886488	[155]	[15]	-7	hSpCas9	negative selection	529179
16853103	16853126	19	-	26472758	Raji	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.11711040860813626	[457]	[97]	-1	hSpCas9	negative selection	529180
16854145	16854168	19	-	26472758	Raji	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-0.20340400190856256	[128]	[25]	-2	hSpCas9	negative selection	529181
16829418	16829441	19	+	26472758	K562	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.11703773140755286	[369]	[287]	-1	hSpCas9	negative selection	720290
16862958	16862981	19	+	26472758	K562	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.23615053585449264	[592]	[424]	-2	hSpCas9	negative selection	720291
16829876	16829899	19	+	26472758	K562	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	-0.35222557810234467	[185]	[122]	-2	hSpCas9	negative selection	720292
16841767	16841790	19	+	26472758	K562	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.3763615982645397	[448]	[491]	3	hSpCas9	negative selection	720293
16841821	16841844	19	+	26472758	K562	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.0592038551995393	[248]	[218]	0	hSpCas9	negative selection	720294
16846969	16846992	19	+	26472758	K562	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-1.608024083919695	[194]	[53]	-7	hSpCas9	negative selection	720295
16847033	16847056	19	+	26472758	K562	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.644802982874137	[568]	[750]	5	hSpCas9	negative selection	720296
16851499	16851522	19	-	26472758	K562	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	-0.9697060776864006	[289]	[124]	-5	hSpCas9	negative selection	720297
16853103	16853126	19	-	26472758	K562	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.28172881439166975	[732]	[508]	-2	hSpCas9	negative selection	720298
16854145	16854168	19	-	26472758	K562	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-0.5664251804710371	[206]	[117]	-4	hSpCas9	negative selection	720299
16829402	16829425	19	+	26627737	DLD1	viability	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	-0.05663486668100948	[2105]	[690,477,710]	0	hSpCas9	negative selection	803168
16829799	16829822	19	+	26627737	DLD1	viability	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.17148383794485622	[1673]	[657,262,463]	-2	hSpCas9	negative selection	803169
16831626	16831649	19	+	26627737	DLD1	viability	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	-1.2196555187714435	[496]	[58,7,121]	-8	hSpCas9	negative selection	803170
16841766	16841789	19	+	26627737	DLD1	viability	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	-0.16172616458776723	[294]	[52,149,51]	-2	hSpCas9	negative selection	803171
16846997	16847020	19	-	26627737	DLD1	viability	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.4191568384309675	[274]	[133,42,157]	4	hSpCas9	negative selection	803172
16851513	16851536	19	-	26627737	DLD1	viability	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.13727644782464332	[202]	[58,75,73]	1	hSpCas9	negative selection	803173
16829402	16829425	19	+	26627737	GBM cells	viability after 5 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.012442820516099795	[683]	[331,407]	0	hSpCas9	negative selection	885483
16829799	16829822	19	+	26627737	GBM cells	viability after 5 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	0.6096402322638175	[687]	[625,499]	8	hSpCas9	negative selection	885484
16831626	16831649	19	+	26627737	GBM cells	viability after 5 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.05363646968432756	[211]	[119,115]	0	hSpCas9	negative selection	885485
16841766	16841789	19	+	26627737	GBM cells	viability after 5 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.1609502211564026	[240]	[96,191]	2	hSpCas9	negative selection	885486
16846997	16847020	19	-	26627737	GBM cells	viability after 5 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.42888714100918923	[204]	[155,139]	6	hSpCas9	negative selection	885487
16851513	16851536	19	-	26627737	GBM cells	viability after 5 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.8347835374659698	[22]	[19,23]	9	hSpCas9	negative selection	885488
16829402	16829425	19	+	26627737	GBM cells	viability after 13 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	-0.4386080401634329	[683]	[280,267]	-5	hSpCas9	negative selection	967798
16829799	16829822	19	+	26627737	GBM cells	viability after 13 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	0.158749481081633	[687]	[467,374]	2	hSpCas9	negative selection	967799
16831626	16831649	19	+	26627737	GBM cells	viability after 13 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.9986576797533859	[211]	[252,210]	9	hSpCas9	negative selection	967800
16841766	16841789	19	+	26627737	GBM cells	viability after 13 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.15961949227498734	[240]	[198,102]	2	hSpCas9	negative selection	967801
16846997	16847020	19	-	26627737	GBM cells	viability after 13 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.5374220968365658	[204]	[204,125]	6	hSpCas9	negative selection	967802
16851513	16851536	19	-	26627737	GBM cells	viability after 13 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.386121976432805	[22]	[12,18]	5	hSpCas9	negative selection	967803
16829402	16829425	19	+	26627737	GBM cells	viability after 21 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	-0.8652724536000181	[683]	[215,192]	-6	hSpCas9	negative selection	1050113
16829799	16829822	19	+	26627737	GBM cells	viability after 21 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.015993669538970856	[687]	[365,372]	0	hSpCas9	negative selection	1050114
16831626	16831649	19	+	26627737	GBM cells	viability after 21 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.8046399877817074	[211]	[196,204]	7	hSpCas9	negative selection	1050115
16841766	16841789	19	+	26627737	GBM cells	viability after 21 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.06443968737070327	[240]	[138,134]	0	hSpCas9	negative selection	1050116
16846997	16847020	19	-	26627737	GBM cells	viability after 21 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.5888661834448943	[204]	[178,156]	6	hSpCas9	negative selection	1050117
16851513	16851536	19	-	26627737	GBM cells	viability after 21 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	-0.30863326548011427	[22]	[7,11]	-3	hSpCas9	negative selection	1050118
16829402	16829425	19	+	26627737	RPE1	viability after 9 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.21118441840440738	[2248]	[484,1240]	1	hSpCas9	negative selection	1132428
16829799	16829822	19	+	26627737	RPE1	viability after 9 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-1.1417804015167137	[4423]	[411,905]	-7	hSpCas9	negative selection	1132429
16831626	16831649	19	+	26627737	RPE1	viability after 9 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	1.6635122270986968	[264]	[202,339]	8	hSpCas9	negative selection	1132430
16841766	16841789	19	+	26627737	RPE1	viability after 9 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	1.3019803732506596	[356]	[251,305]	7	hSpCas9	negative selection	1132431
16846997	16847020	19	-	26627737	RPE1	viability after 9 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.05299515913615968	[754]	[194,309]	0	hSpCas9	negative selection	1132432
16851513	16851536	19	-	26627737	RPE1	viability after 9 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.7655646521897503	[254]	[119,155]	5	hSpCas9	negative selection	1132433
16829402	16829425	19	+	26627737	RPE1	viability after 12 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.6152885201154481	[2248]	[741,1119]	4	hSpCas9	negative selection	1214743
16829799	16829822	19	+	26627737	RPE1	viability after 12 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.9440281978212939	[4423]	[542,696]	-6	hSpCas9	negative selection	1214744
16831626	16831649	19	+	26627737	RPE1	viability after 12 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	1.240296757590358	[264]	[191,142]	7	hSpCas9	negative selection	1214745
16841766	16841789	19	+	26627737	RPE1	viability after 12 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	1.8098748306248782	[356]	[243,433]	8	hSpCas9	negative selection	1214746
16846997	16847020	19	-	26627737	RPE1	viability after 12 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.5774553538131156	[754]	[342,259]	4	hSpCas9	negative selection	1214747
16851513	16851536	19	-	26627737	RPE1	viability after 12 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.48886574736699284	[254]	[83,108]	3	hSpCas9	negative selection	1214748
16829402	16829425	19	+	26627737	RPE1	viability after 15 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.5025532000238888	[2248]	[855,944]	3	hSpCas9	negative selection	1297058
16829799	16829822	19	+	26627737	RPE1	viability after 15 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-1.2748802779005195	[4423]	[422,607]	-7	hSpCas9	negative selection	1297059
16831626	16831649	19	+	26627737	RPE1	viability after 15 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.3704328709222626	[264]	[73,118]	2	hSpCas9	negative selection	1297060
16841766	16841789	19	+	26627737	RPE1	viability after 15 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	1.6535166015444458	[356]	[277,355]	8	hSpCas9	negative selection	1297061
16846997	16847020	19	-	26627737	RPE1	viability after 15 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.04066743950109584	[754]	[293,147]	0	hSpCas9	negative selection	1297062
16851513	16851536	19	-	26627737	RPE1	viability after 15 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	1.0799538485781879	[254]	[124,178]	6	hSpCas9	negative selection	1297063
16829402	16829425	19	+	26627737	RPE1	viability after 18 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.46553728946228023	[2248]	[679,1006]	3	hSpCas9	negative selection	1379373
16829799	16829822	19	+	26627737	RPE1	viability after 18 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.9049767490180929	[4423]	[581,696]	-5	hSpCas9	negative selection	1379374
16831626	16831649	19	+	26627737	RPE1	viability after 18 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.551523378294865	[264]	[113,94]	3	hSpCas9	negative selection	1379375
16841766	16841789	19	+	26627737	RPE1	viability after 18 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	1.3578122500356489	[356]	[200,295]	7	hSpCas9	negative selection	1379376
16846997	16847020	19	-	26627737	RPE1	viability after 18 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.43167811804485945	[754]	[356,186]	2	hSpCas9	negative selection	1379377
16851513	16851536	19	-	26627737	RPE1	viability after 18 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	1.2457198963156317	[254]	[124,203]	7	hSpCas9	negative selection	1379378
16829402	16829425	19	+	26627737	HeLa	viability after 8 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.6901531365887443	[1094]	[1093,679,614]	6	hSpCas9	negative selection	1461688
16829799	16829822	19	+	26627737	HeLa	viability after 8 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.05659797272222544	[907]	[452,325,376]	0	hSpCas9	negative selection	1461689
16831626	16831649	19	+	26627737	HeLa	viability after 8 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	-0.7687643273028587	[639]	[280,112,124]	-6	hSpCas9	negative selection	1461690
16841766	16841789	19	+	26627737	HeLa	viability after 8 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.19393507569178275	[457]	[472,157,114]	1	hSpCas9	negative selection	1461691
16846997	16847020	19	-	26627737	HeLa	viability after 8 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.33231718353191275	[306]	[209,138,164]	3	hSpCas9	negative selection	1461692
16851513	16851536	19	-	26627737	HeLa	viability after 8 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	1.3599609657951441	[327]	[320,489,283]	8	hSpCas9	negative selection	1461693
16829402	16829425	19	+	26627737	HeLa	viability after 12 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.6442340030463689	[1094]	[751,773,589]	5	hSpCas9	negative selection	1544003
16829799	16829822	19	+	26627737	HeLa	viability after 12 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	0.6804188547576977	[907]	[536,395,890]	5	hSpCas9	negative selection	1544004
16831626	16831649	19	+	26627737	HeLa	viability after 12 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	-0.4653198304534738	[639]	[305,191,79]	-4	hSpCas9	negative selection	1544005
16841766	16841789	19	+	26627737	HeLa	viability after 12 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.14249726117416844	[457]	[233,241,147]	1	hSpCas9	negative selection	1544006
16846997	16847020	19	-	26627737	HeLa	viability after 12 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	-0.31117238451491536	[306]	[71,138,90]	-3	hSpCas9	negative selection	1544007
16851513	16851536	19	-	26627737	HeLa	viability after 12 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	1.0212034136495007	[327]	[292,254,279]	7	hSpCas9	negative selection	1544008
16829402	16829425	19	+	26627737	HeLa	viability after 15 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.9506981322092458	[1094]	[608,1069,912]	7	hSpCas9	negative selection	1626318
16829799	16829822	19	+	26627737	HeLa	viability after 15 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	0.6846205902388913	[907]	[480,718,582]	5	hSpCas9	negative selection	1626319
16831626	16831649	19	+	26627737	HeLa	viability after 15 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	-0.1331652303625771	[639]	[196,184,338]	-1	hSpCas9	negative selection	1626320
16841766	16841789	19	+	26627737	HeLa	viability after 15 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.08753462957451175	[457]	[141,279,170]	0	hSpCas9	negative selection	1626321
16846997	16847020	19	-	26627737	HeLa	viability after 15 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.1459166296310612	[306]	[138,195,74]	1	hSpCas9	negative selection	1626322
16851513	16851536	19	-	26627737	HeLa	viability after 15 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	1.0520304643628466	[327]	[150,394,286]	7	hSpCas9	negative selection	1626323
16829402	16829425	19	+	26627737	HeLa	viability after 18 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.9501736552814481	[1094]	[415,875,912]	7	hSpCas9	negative selection	1708633
16829799	16829822	19	+	26627737	HeLa	viability after 18 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	0.6740763004776762	[907]	[304,606,582]	5	hSpCas9	negative selection	1708634
16831626	16831649	19	+	26627737	HeLa	viability after 18 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	-0.10389457664727897	[639]	[136,158,338]	-1	hSpCas9	negative selection	1708635
16841766	16841789	19	+	26627737	HeLa	viability after 18 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.07567418828380773	[457]	[91,231,170]	0	hSpCas9	negative selection	1708636
16846997	16847020	19	-	26627737	HeLa	viability after 18 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.15607735495230718	[306]	[92,164,74]	1	hSpCas9	negative selection	1708637
16851513	16851536	19	-	26627737	HeLa	viability after 18 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.9885804584924422	[327]	[86,315,286]	7	hSpCas9	negative selection	1708638
16829402	16829425	19	+	26627737	HCT116	viability after 6 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.3094332650755831	[3258]	[563,673]	1	hSpCas9	negative selection	1790948
16829799	16829822	19	+	26627737	HCT116	viability after 6 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.15886477203030758	[2256]	[603,159]	-1	hSpCas9	negative selection	1790949
16831626	16831649	19	+	26627737	HCT116	viability after 6 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	1.5346009836070371	[304]	[9,209]	7	hSpCas9	negative selection	1790950
16841766	16841789	19	+	26627737	HCT116	viability after 6 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	-0.8474322556565326	[564]	[127,5]	-5	hSpCas9	negative selection	1790951
16846997	16847020	19	-	26627737	HCT116	viability after 6 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	-0.8939090498059701	[207]	[34,7]	-5	hSpCas9	negative selection	1790952
16851513	16851536	19	-	26627737	HCT116	viability after 6 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	-0.9804455705715578	[854]	[129,33]	-5	hSpCas9	negative selection	1790953
16829402	16829425	19	+	26627737	HCT116	viability after 8 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	-0.22201389426974805	[1370]	[465,671,799]	-3	hSpCas9	negative selection	1873263
16829799	16829822	19	+	26627737	HCT116	viability after 8 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	0.33789428505347685	[585]	[472,466,286]	3	hSpCas9	negative selection	1873264
16831626	16831649	19	+	26627737	HCT116	viability after 8 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.3784272361669555	[175]	[124,111,140]	4	hSpCas9	negative selection	1873265
16841766	16841789	19	+	26627737	HCT116	viability after 8 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	-0.1365577064005184	[337]	[158,171,176]	-1	hSpCas9	negative selection	1873266
16846997	16847020	19	-	26627737	HCT116	viability after 8 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	-0.02614167530881783	[297]	[166,165,150]	0	hSpCas9	negative selection	1873267
16851513	16851536	19	-	26627737	HCT116	viability after 8 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.4678955933778866	[319]	[316,176,238]	5	hSpCas9	negative selection	1873268
16829402	16829425	19	+	26627737	HCT116	viability after 9 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.1269155482697948	[3258]	[823,1049]	1	hSpCas9	negative selection	1955578
16829799	16829822	19	+	26627737	HCT116	viability after 9 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.1558122091983445	[2256]	[526,551]	-1	hSpCas9	negative selection	1955579
16831626	16831649	19	+	26627737	HCT116	viability after 9 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	1.523466502399529	[304]	[313,170]	8	hSpCas9	negative selection	1955580
16841766	16841789	19	+	26627737	HCT116	viability after 9 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.3956487622890581	[564]	[193,201]	3	hSpCas9	negative selection	1955581
16846997	16847020	19	-	26627737	HCT116	viability after 9 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.4552112787972109	[207]	[69,80]	3	hSpCas9	negative selection	1955582
16851513	16851536	19	-	26627737	HCT116	viability after 9 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	-1.441854591569401	[854]	[159,23]	-7	hSpCas9	negative selection	1955583
16829402	16829425	19	+	26627737	HCT116	viability after 12 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	-0.1305434088671502	[1370]	[562,622,795]	-1	hSpCas9	negative selection	2037893
16829799	16829822	19	+	26627737	HCT116	viability after 12 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	0.28779167252647986	[585]	[310,435,387]	3	hSpCas9	negative selection	2037894
16831626	16831649	19	+	26627737	HCT116	viability after 12 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.8206814236351198	[175]	[148,189,152]	7	hSpCas9	negative selection	2037895
16841766	16841789	19	+	26627737	HCT116	viability after 12 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.1252470114655107	[337]	[202,135,239]	1	hSpCas9	negative selection	2037896
16846997	16847020	19	-	26627737	HCT116	viability after 12 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.0495019664505338	[297]	[56,225,213]	0	hSpCas9	negative selection	2037897
16851513	16851536	19	-	26627737	HCT116	viability after 12 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.7595375731899975	[319]	[352,197,294]	6	hSpCas9	negative selection	2037898
16829402	16829425	19	+	26627737	HCT116	viability after 15 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	-0.049558451291445316	[1370]	[789,662,831]	0	hSpCas9	negative selection	2120208
16829799	16829822	19	+	26627737	HCT116	viability after 15 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	0.7036084488413931	[585]	[532,362,743]	6	hSpCas9	negative selection	2120209
16831626	16831649	19	+	26627737	HCT116	viability after 15 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.6446659295199245	[175]	[236,115,130]	6	hSpCas9	negative selection	2120210
16841766	16841789	19	+	26627737	HCT116	viability after 15 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	-0.37878789746520436	[337]	[208,168,77]	-4	hSpCas9	negative selection	2120211
16846997	16847020	19	-	26627737	HCT116	viability after 15 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.020818830959151727	[297]	[205,159,158]	0	hSpCas9	negative selection	2120212
16851513	16851536	19	-	26627737	HCT116	viability after 15 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.33482827990984226	[319]	[190,152,344]	3	hSpCas9	negative selection	2120213
16829402	16829425	19	+	26627737	HCT116	viability after 18 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.465876515724307	[1370]	[856,813,1089]	4	hSpCas9	negative selection	2202523
16829799	16829822	19	+	26627737	HCT116	viability after 18 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	0.3307379705889043	[585]	[412,314,342]	3	hSpCas9	negative selection	2202524
16831626	16831649	19	+	26627737	HCT116	viability after 18 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.5948021496475753	[175]	[134,95,157]	5	hSpCas9	negative selection	2202525
16841766	16841789	19	+	26627737	HCT116	viability after 18 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.3932806674285839	[337]	[223,217,200]	3	hSpCas9	negative selection	2202526
16846997	16847020	19	-	26627737	HCT116	viability after 18 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	-0.3815749989183328	[297]	[96,96,139]	-4	hSpCas9	negative selection	2202527
16851513	16851536	19	-	26627737	HCT116	viability after 18 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.4576580471384865	[319]	[212,86,351]	4	hSpCas9	negative selection	2202528
16829412	16829435	19	+	24336569	HL60	viability	ACTTCGGACATGGCGCACGCTGG	SIN3B	ENSG00000127511	0.7316189088848994	[789]	[2775]	6	hSpCas9	negative selection	2295123
16829418	16829441	19	+	24336569	HL60	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.2162347673435948	[711]	[1296]	-2	hSpCas9	negative selection	2295124
16829424	16829447	19	+	24336569	HL60	viability	GCGCACGCTGGCGGTGGCAGCGG	SIN3B	ENSG00000127511	-0.050099929719561204	[454]	[929]	0	hSpCas9	negative selection	2295125
16829439	16829462	19	+	24336569	HL60	viability	GGCAGCGGTGGCAGCGGTGCCGG	SIN3B	ENSG00000127511	-1.1138855783212738	[539]	[527]	-7	hSpCas9	negative selection	2295126
16829512	16829535	19	-	24336569	HL60	viability	CGGCAGCTTCTCGTGGCCTGCGG	SIN3B	ENSG00000127511	-0.7508664109824679	[729]	[917]	-6	hSpCas9	negative selection	2295127
16829519	16829542	19	-	24336569	HL60	viability	CGTGCACCGGCAGCTTCTCGTGG	SIN3B	ENSG00000127511	1.0344350191309055	[262]	[1139]	7	hSpCas9	negative selection	2295128
16829532	16829555	19	-	24336569	HL60	viability	GGGACGCCACTCACGTGCACCGG	SIN3B	ENSG00000127511	-0.528091912351209	[1261]	[1851]	-5	hSpCas9	negative selection	2295129
16829793	16829816	19	+	24336569	HL60	viability	AGAAGACGCCCTCACCTATCTGG	SIN3B	ENSG00000127511	-1.557197531595294	[88]	[63]	-8	hSpCas9	negative selection	2295130
16829799	16829822	19	+	24336569	HL60	viability	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.5278657708170749	[61]	[90]	-5	hSpCas9	negative selection	2295131
16829807	16829830	19	-	24336569	HL60	viability	GATCTTCACCTGGTCCAGATAGG	SIN3B	ENSG00000127511	1.0777344942203577	[449]	[2009]	8	hSpCas9	negative selection	2295132
16829412	16829435	19	+	24336569	KBM7	viability	ACTTCGGACATGGCGCACGCTGG	SIN3B	ENSG00000127511	0.5283858716092005	[574]	[2261]	5	hSpCas9	negative selection	2362300
16829418	16829441	19	+	24336569	KBM7	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.5804857061887205	[516]	[942]	-5	hSpCas9	negative selection	2362301
16829424	16829447	19	+	24336569	KBM7	viability	GCGCACGCTGGCGGTGGCAGCGG	SIN3B	ENSG00000127511	0.030919153891103557	[491]	[1370]	0	hSpCas9	negative selection	2362302
16829439	16829462	19	+	24336569	KBM7	viability	GGCAGCGGTGGCAGCGGTGCCGG	SIN3B	ENSG00000127511	-0.9360788577687473	[328]	[468]	-6	hSpCas9	negative selection	2362303
16829512	16829535	19	-	24336569	KBM7	viability	CGGCAGCTTCTCGTGGCCTGCGG	SIN3B	ENSG00000127511	0.5671339682168235	[438]	[1773]	5	hSpCas9	negative selection	2362304
16829519	16829542	19	-	24336569	KBM7	viability	CGTGCACCGGCAGCTTCTCGTGG	SIN3B	ENSG00000127511	0.3772843753634634	[467]	[1657]	3	hSpCas9	negative selection	2362305
16829532	16829555	19	-	24336569	KBM7	viability	GGGACGCCACTCACGTGCACCGG	SIN3B	ENSG00000127511	0.27659145209222147	[973]	[3217]	2	hSpCas9	negative selection	2362306
16829793	16829816	19	+	24336569	KBM7	viability	AGAAGACGCCCTCACCTATCTGG	SIN3B	ENSG00000127511	0.4099453217386564	[108]	[394]	4	hSpCas9	negative selection	2362307
16829799	16829822	19	+	24336569	KBM7	viability	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.9780939132476623	[142]	[197]	-6	hSpCas9	negative selection	2362308
16829807	16829830	19	-	24336569	KBM7	viability	GATCTTCACCTGGTCCAGATAGG	SIN3B	ENSG00000127511	0.5245175748193948	[508]	[1996]	5	hSpCas9	negative selection	2362309
16841782	16841805	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTCCTCTGCACCGTCCCCGTGG	SIN3B	ENSG00000127511	0.06538923863144891	[4,4]	[4,3]	1	hSpCas9	positive selection	3020344
16863772	16863795	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGAAGCGCTCGTCCTCACAGCGG	SIN3B	ENSG00000127511	-0.012697326094234962	[3,2]	[3,1]	0	hSpCas9	positive selection	3020345
16862524	16862547	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTCCTCCCACTGCACTTGGG	SIN3B	ENSG00000127511	0.4652174514576591	[4,4]	[3,6]	8	hSpCas9	positive selection	3020346
16841768	16841791	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.8124932427840269	[2,2]	[3,5]	9	hSpCas9	positive selection	3020347
16841782	16841805	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTCCTCTGCACCGTCCCCGTGG	SIN3B	ENSG00000127511	0.0911081288544843	[4,4]	[3,2]	1	hSpCas9	positive selection	3088202
16863772	16863795	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGAAGCGCTCGTCCTCACAGCGG	SIN3B	ENSG00000127511	-0.02347659802718534	[3,3]	[2,1]	0	hSpCas9	positive selection	3088203
16862524	16862547	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTCCTCCCACTGCACTTGGG	SIN3B	ENSG00000127511	-0.07059929019643604	[4,4]	[2,2]	-1	hSpCas9	positive selection	3088204
16841768	16841791	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.6485706778991962	[2,2]	[2,4]	9	hSpCas9	positive selection	3088205
16831626	16831649		+	24336571	A375	resistance to PLX after 7 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	-0.03022813158125237	[8,7]	[7,8]	-1	hSpCas9	positive selection	3144292
16851453	16851476		+	24336571	A375	resistance to PLX after 7 days	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.16890216936431632	[9,11]	[12,11]	5	hSpCas9	positive selection	3144293
16851515	16851538		-	24336571	A375	resistance to PLX after 7 days	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.05168691618818655	[23,21]	[23,22]	1	hSpCas9	positive selection	3144294
16831486	16831509		+	24336571	A375	resistance to PLX after 7 days	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.0089319690668212	[14,10]	[11,12]	0	hSpCas9	positive selection	3144295
16831626	16831649		+	24336571	A375	resistance to PLX after 14 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.6024032570366384	[11,7]	[6,6]	5	hSpCas9	positive selection	3202085
16851453	16851476		+	24336571	A375	resistance to PLX after 14 days	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.13288525393708095	[15,14]	[6,7]	1	hSpCas9	positive selection	3202086
16851515	16851538		-	24336571	A375	resistance to PLX after 14 days	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	-0.39406705284090016	[24,24]	[8,7]	-5	hSpCas9	positive selection	3202087
16831486	16831509		+	24336571	A375	resistance to PLX after 14 days	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.08659019411094518	[11,8]	[4,3]	-1	hSpCas9	positive selection	3202088
16831626	16831649		+	24336571	A375	viability after 7 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	-0.7825856359893392	[15]	[8,7]	-8	hSpCas9	negative selection	3259878
16851453	16851476		+	24336571	A375	viability after 7 days	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.5024912514957471	[16]	[9,11]	-6	hSpCas9	negative selection	3259879
16851515	16851538		-	24336571	A375	viability after 7 days	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.23468424378877695	[19]	[23,21]	3	hSpCas9	negative selection	3259880
16831486	16831509		+	24336571	A375	viability after 7 days	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.475361791219854	[18]	[14,10]	-6	hSpCas9	negative selection	3259881
16831626	16831649		+	24336571	A375	viability after 14 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	-0.5187250997508754	[15]	[11,7]	-6	hSpCas9	negative selection	3317671
16851453	16851476		+	24336571	A375	viability after 14 days	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.05415569768432593	[16]	[15,14]	0	hSpCas9	negative selection	3317672
16851515	16851538		-	24336571	A375	viability after 14 days	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.38693527838997244	[19]	[24,24]	5	hSpCas9	negative selection	3317673
16831486	16831509		+	24336571	A375	viability after 14 days	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.6839838772314358	[18]	[11,8]	-7	hSpCas9	negative selection	3317674
16831540	16831563	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.5042250209986441	[216,216]	[0,0]	-3	hSpCas9	positive selection	3392473
16851453	16851476	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	2.8650087886670748	[20,20]	[0,0]	8	hSpCas9	positive selection	3392474
16853095	16853118	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	2.399345216318263	[28,28]	[0,0]	8	hSpCas9	positive selection	3392475
16841782	16841805	19	-	26780180	HT29	viability (Avana library 4 designs)	AGTCCTCTGCACCGTCCCCGTGG	SIN3B	ENSG00000127511	-0.0557746028249743	[]	[]	-1	hSpCas9	negative selection	3458854
16863772	16863795	19	-	26780180	HT29	viability (Avana library 4 designs)	CGAAGCGCTCGTCCTCACAGCGG	SIN3B	ENSG00000127511	0.925745668598181	[]	[]	3	hSpCas9	negative selection	3458855
16862524	16862547	19	-	26780180	HT29	viability (Avana library 4 designs)	GCTGTCCTCCCACTGCACTTGGG	SIN3B	ENSG00000127511	0.670680250375496	[]	[]	2	hSpCas9	negative selection	3458856
16841767	16841790	19	+	26780180	HT29	viability (Avana library 4 designs)	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	2.0252924612564	[]	[]	7	hSpCas9	negative selection	3458857
16841767	16841790	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-2.80879025234044	[]	[]	-3	hSpCas9	negative selection	3558497
16841782	16841805	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTCCTCTGCACCGTCCCCGTGG	SIN3B	ENSG00000127511	5.56976750278898	[]	[]	8	hSpCas9	negative selection	3558498
16863772	16863795	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAAGCGCTCGTCCTCACAGCGG	SIN3B	ENSG00000127511	1.86303930003308	[]	[]	2	hSpCas9	negative selection	3558499
16862524	16862547	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTCCTCCCACTGCACTTGGG	SIN3B	ENSG00000127511	2.05654682945435	[]	[]	3	hSpCas9	negative selection	3558500
16865585	16865608	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGCTCTCGATGATCTCCGGGG	SIN3B	ENSG00000127511	6.29139267262433	[]	[]	9	hSpCas9	negative selection	3558501
16854145	16854168	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-5.58521648057873	[]	[]	-6	hSpCas9	negative selection	3558502
16841767	16841790	19	+	26780180	A375	viability (Avana lentiGuide)	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	11.7364283467818	[]	[]	7	hSpCas9	negative selection	3667156
16841782	16841805	19	-	26780180	A375	viability (Avana lentiGuide)	AGTCCTCTGCACCGTCCCCGTGG	SIN3B	ENSG00000127511	2.3978543075481	[]	[]	2	hSpCas9	negative selection	3667157
16863772	16863795	19	-	26780180	A375	viability (Avana lentiGuide)	CGAAGCGCTCGTCCTCACAGCGG	SIN3B	ENSG00000127511	-0.471342342634016	[]	[]	0	hSpCas9	negative selection	3667158
16862524	16862547	19	-	26780180	A375	viability (Avana lentiGuide)	GCTGTCCTCCCACTGCACTTGGG	SIN3B	ENSG00000127511	0.231891726289669	[]	[]	0	hSpCas9	negative selection	3667159
16865585	16865608	19	-	26780180	A375	viability (Avana lentiGuide)	GAGGCTCTCGATGATCTCCGGGG	SIN3B	ENSG00000127511	9.99243747166054	[]	[]	7	hSpCas9	negative selection	3667160
16854145	16854168	19	-	26780180	A375	viability (Avana lentiGuide)	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-4.97861871886286	[]	[]	-8	hSpCas9	negative selection	3667161
16841767	16841790	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.2826161658254359	[4]	[3,3]	-4	hSpCas9	positive selection	3775763
16841782	16841805	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTCCTCTGCACCGTCCCCGTGG	SIN3B	ENSG00000127511	0.1879003861992104	[5]	[7,5]	5	hSpCas9	positive selection	3775764
16863772	16863795	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAAGCGCTCGTCCTCACAGCGG	SIN3B	ENSG00000127511	-0.07336262832677329	[4]	[4,3]	-1	hSpCas9	positive selection	3775765
16862524	16862547	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTCCTCCCACTGCACTTGGG	SIN3B	ENSG00000127511	0.03722890169796211	[4]	[4,5]	0	hSpCas9	positive selection	3775766
16865585	16865608	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGCTCTCGATGATCTCCGGGG	SIN3B	ENSG00000127511	0.2792441839040894	[4]	[5,5]	7	hSpCas9	positive selection	3775767
16854145	16854168	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-0.33173631326263037	[4]	[3,2]	-5	hSpCas9	positive selection	3775768
16841767	16841790	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.05840087728429344	[4]	[3,3]	-1	hSpCas9	positive selection	3884370
16841782	16841805	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTCCTCTGCACCGTCCCCGTGG	SIN3B	ENSG00000127511	-0.009417677602536367	[6]	[5,4]	0	hSpCas9	positive selection	3884371
16863772	16863795	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAAGCGCTCGTCCTCACAGCGG	SIN3B	ENSG00000127511	-0.39010655833267976	[5]	[4,2]	-5	hSpCas9	positive selection	3884372
16862524	16862547	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTCCTCCCACTGCACTTGGG	SIN3B	ENSG00000127511	0.06711411650743371	[6]	[5,5]	1	hSpCas9	positive selection	3884373
16865585	16865608	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGCTCTCGATGATCTCCGGGG	SIN3B	ENSG00000127511	-0.6556869989278895	[4]	[2,0]	-7	hSpCas9	positive selection	3884374
16854145	16854168	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-0.24975866479535686	[4]	[2,2]	-3	hSpCas9	positive selection	3884375
16853095	16853118	19	+	26780180	A375	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	1.03124156861855	[]	[]	5	hSpCas9	negative selection	3994427
16851453	16851476	19	+	26780180	A375	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.356135094793376	[]	[]	0	hSpCas9	negative selection	3994428
16831540	16831563	19	+	26780180	A375	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	1.98432539336622	[]	[]	9	hSpCas9	negative selection	3994429
16853103	16853126	19	-	26780180	A375	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	2.02709490021455	[]	[]	9	hSpCas9	negative selection	3994430
16851515	16851538	19	-	26780180	A375	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.523188934429081	[]	[]	1	hSpCas9	negative selection	3994431
16831486	16831509	19	+	26780180	A375	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	1.84243716417224	[]	[]	9	hSpCas9	negative selection	3994432
16853095	16853118	19	+	26780180	HT29	viability (GeCKOv2 library)	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	1.12217895584175	[]	[]	5	hSpCas9	negative selection	4102393
16851453	16851476	19	+	26780180	HT29	viability (GeCKOv2 library)	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.729948139812399	[]	[]	3	hSpCas9	negative selection	4102394
16831540	16831563	19	+	26780180	HT29	viability (GeCKOv2 library)	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	0.73535479880276	[]	[]	3	hSpCas9	negative selection	4102395
16853103	16853126	19	-	26780180	HT29	viability (GeCKOv2 library)	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	1.12244002283469	[]	[]	5	hSpCas9	negative selection	4102396
16851515	16851538	19	-	26780180	HT29	viability (GeCKOv2 library)	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.767691782775931	[]	[]	3	hSpCas9	negative selection	4102397
16831486	16831509	19	+	26780180	HT29	viability (GeCKOv2 library)	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	1.75766438412499	[]	[]	8	hSpCas9	negative selection	4102398
16831626	16831649	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.19136830965039056	[3]	[1,2]	5	hSpCas9	positive selection	4170239
16851453	16851476	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.007531016587324205	[3]	[1,2]	0	hSpCas9	positive selection	4170240
16851515	16851538	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	-0.06240273380450165	[4]	[2,3]	-1	hSpCas9	positive selection	4170241
16831486	16831509	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.2014553599535373	[3]	[1,1]	-5	hSpCas9	positive selection	4170242
16831626	16831649	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	1.0976409172056534	[3]	[3,0,1,3]	8	hSpCas9	positive selection	4234261
16851453	16851476	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.02880317901202268	[3]	[3,2,0,0]	0	hSpCas9	positive selection	4234262
16851515	16851538	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.936355988226494	[4]	[3,3,1,3]	6	hSpCas9	positive selection	4234263
16831486	16831509	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.04777215692807937	[3]	[2,2,0,0]	0	hSpCas9	positive selection	4234264
16851515	16851538	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.11936634767534413	[2]	[2,1]	2	hSpCas9	positive selection	4297816
16831486	16831509	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.013173236012103351	[3]	[2,2]	0	hSpCas9	positive selection	4297817
16853103	16853126	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.0884769375825932	[3]	[2,1]	-2	hSpCas9	positive selection	4297818
16831540	16831563	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.5816874907803958	[3]	[2,0]	-8	hSpCas9	positive selection	4362070
16851453	16851476	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.5191149701766855	[0]	[0,0]	-8	hSpCas9	positive selection	4362071
16853095	16853118	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.7204130766815352	[1]	[0,0]	-9	hSpCas9	positive selection	4362072
16865558	16865580	19	-	27760321	OCIAML3	viability	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	0.07058195801150147	[179,140]	[90,182]	0	hSpCas9	negative selection	4439033
16831551	16831573	19	-	27760321	OCIAML3	viability	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	-0.0906970163994465	[216,171]	[88,210]	-1	hSpCas9	negative selection	4439034
16841768	16841790	19	+	27760321	OCIAML3	viability	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.5119381335755071	[1169,1077]	[526,732]	-5	hSpCas9	negative selection	4439035
16862904	16862926	19	-	27760321	OCIAML3	viability	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	0.16734293084761298	[713,610]	[586,570]	2	hSpCas9	negative selection	4439036
16865558	16865580	19	-	27760321	OCIAML2	viability	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	-0.8382259059251722	[179,140]	[72,70]	-7	hSpCas9	negative selection	4522496
16831551	16831573	19	-	27760321	OCIAML2	viability	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	-0.7248617437521743	[216,171]	[88,101]	-6	hSpCas9	negative selection	4522497
16841768	16841790	19	+	27760321	OCIAML2	viability	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.3250742263538162	[1169,1077]	[632,847]	-4	hSpCas9	negative selection	4522498
16862904	16862926	19	-	27760321	OCIAML2	viability	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	-0.13710257144562144	[713,610]	[487,482]	-2	hSpCas9	negative selection	4522499
16865558	16865580	19	-	27760321	MV411	viability	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	-3.4854767239475573	[179,140]	[0,21]	-9	hSpCas9	negative selection	4605959
16831551	16831573	19	-	27760321	MV411	viability	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	-2.3278434670804042	[216,171]	[32,13]	-8	hSpCas9	negative selection	4605960
16841768	16841790	19	+	27760321	MV411	viability	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.6901999127014822	[1169,1077]	[296,703]	-5	hSpCas9	negative selection	4605961
16862904	16862926	19	-	27760321	MV411	viability	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	-1.0864516169387026	[713,610]	[253,131]	-6	hSpCas9	negative selection	4605962
16865558	16865580	19	-	27760321	HL60	viability	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	-0.1066238729457285	[179,140]	[135,104]	-1	hSpCas9	negative selection	4689422
16831551	16831573	19	-	27760321	HL60	viability	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	0.13803236835776977	[216,171]	[181,164]	1	hSpCas9	negative selection	4689423
16841768	16841790	19	+	27760321	HL60	viability	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.40957730709057616	[1169,1077]	[1020,1429]	5	hSpCas9	negative selection	4689424
16862904	16862926	19	-	27760321	HL60	viability	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	-0.39017988858207947	[713,610]	[416,405]	-4	hSpCas9	negative selection	4689425
16865558	16865580	19	-	27760321	HT1080	viability	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	2.3045147243966264	[140,109]	[140,362]	9	hSpCas9	negative selection	4772885
16831551	16831573	19	-	27760321	HT1080	viability	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	2.5888272905020573	[171,133]	[453,270]	9	hSpCas9	negative selection	4772886
16841768	16841790	19	+	27760321	HT1080	viability	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-2.624657226107362	[1077,840]	[71,50]	-7	hSpCas9	negative selection	4772887
16862904	16862926	19	-	27760321	HT1080	viability	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	-4.865910072566559	[610,476]	[5,8]	-8	hSpCas9	negative selection	4772888
16865558	16865580	19	-	27760321	HT29	viability after 7 days	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	-0.7393224731752537	[140,109]	[173,34,91]	-8	hSpCas9	negative selection	4856348
16831551	16831573	19	-	27760321	HT29	viability after 7 days	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	-0.11970316777836132	[171,133]	[188,174,179]	-2	hSpCas9	negative selection	4856349
16841768	16841790	19	+	27760321	HT29	viability after 7 days	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.037458401214476744	[1077,840]	[1393,1047,1189]	0	hSpCas9	negative selection	4856350
16862904	16862926	19	-	27760321	HT29	viability after 7 days	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	-0.09182731914674014	[610,476]	[655,498,807]	-1	hSpCas9	negative selection	4856351
16865558	16865580	19	-	27760321	HT29	viability after 25 days	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	-0.8215050547720275	[140,109]	[96,92,48]	-6	hSpCas9	negative selection	4939811
16831551	16831573	19	-	27760321	HT29	viability after 25 days	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	-0.3357775263386391	[171,133]	[209,112,81]	-3	hSpCas9	negative selection	4939812
16841768	16841790	19	+	27760321	HT29	viability after 25 days	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.02756698359397136	[1077,840]	[755,989,1548]	0	hSpCas9	negative selection	4939813
16862904	16862926	19	-	27760321	HT29	viability after 25 days	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	0.004794665790785468	[610,476]	[661,469,748]	0	hSpCas9	negative selection	4939814
16865558	16865580	19	-	27760321	HT29	viability after 22 days	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	-0.8594362868734065	[140,109]	[48,82,108]	-6	hSpCas9	negative selection	5023274
16831551	16831573	19	-	27760321	HT29	viability after 22 days	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	-0.9434067222468834	[171,133]	[56,110,108]	-6	hSpCas9	negative selection	5023275
16841768	16841790	19	+	27760321	HT29	viability after 22 days	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.009364635247058661	[1077,840]	[943,1281,1127]	0	hSpCas9	negative selection	5023276
16862904	16862926	19	-	27760321	HT29	viability after 22 days	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	0.059537872944156245	[610,476]	[656,666,641]	0	hSpCas9	negative selection	5023277
16865558	16865580	19	-	27760321	HT29	viability after 19 days	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	-2.201093733437031	[140,109]	[26,56,9]	-8	hSpCas9	negative selection	5106737
16831551	16831573	19	-	27760321	HT29	viability after 19 days	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	-0.3529257940511674	[171,133]	[96,126,180]	-3	hSpCas9	negative selection	5106738
16841768	16841790	19	+	27760321	HT29	viability after 19 days	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.08948297119642334	[1077,840]	[1313,1101,718]	-1	hSpCas9	negative selection	5106739
16862904	16862926	19	-	27760321	HT29	viability after 19 days	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	-0.231118274995205	[610,476]	[443,717,422]	-2	hSpCas9	negative selection	5106740
16865558	16865580	19	-	27760321	HT29	viability after 16 days	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	-1.0731594455257198	[140,109]	[17,88,87]	-7	hSpCas9	negative selection	5190200
16831551	16831573	19	-	27760321	HT29	viability after 16 days	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	-0.2739695635530086	[171,133]	[232,113,86]	-3	hSpCas9	negative selection	5190201
16841768	16841790	19	+	27760321	HT29	viability after 16 days	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.3489087683937857	[1077,840]	[1006,687,852]	-4	hSpCas9	negative selection	5190202
16862904	16862926	19	-	27760321	HT29	viability after 16 days	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	0.12536933462686906	[610,476]	[796,669,536]	1	hSpCas9	negative selection	5190203
16865558	16865580	19	-	27760321	HT29	viability after 13 days	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	-1.0654697222624963	[140,109]	[28,113,65]	-7	hSpCas9	negative selection	5273663
16831551	16831573	19	-	27760321	HT29	viability after 13 days	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	-0.14303233344417143	[171,133]	[213,123,144]	-2	hSpCas9	negative selection	5273664
16841768	16841790	19	+	27760321	HT29	viability after 13 days	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.05479998524989349	[1077,840]	[1088,1299,1083]	0	hSpCas9	negative selection	5273665
16862904	16862926	19	-	27760321	HT29	viability after 13 days	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	-0.20897562275876808	[610,476]	[511,511,609]	-2	hSpCas9	negative selection	5273666
16865558	16865580	19	-	27760321	HT29	viability after 10 days	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	-0.7789502108161495	[140,109]	[27,160,86]	-7	hSpCas9	negative selection	5357126
16831551	16831573	19	-	27760321	HT29	viability after 10 days	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	-0.1746998269215425	[171,133]	[285,63,154]	-2	hSpCas9	negative selection	5357127
16841768	16841790	19	+	27760321	HT29	viability after 10 days	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.07136749229292705	[1077,840]	[1281,1309,1186]	0	hSpCas9	negative selection	5357128
16862904	16862926	19	-	27760321	HT29	viability after 10 days	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	-0.2949865234689772	[610,476]	[530,487,637]	-4	hSpCas9	negative selection	5357129
16865558	16865580	19	-	27760321	MOLM13	viability	TCGCCATAGATGCGATAAATGG	SIN3B	ENSG00000127511	-3.448198185763901	[179,140]	[4,10]	-9	hSpCas9	negative selection	5440589
16831551	16831573	19	-	27760321	MOLM13	viability	AGCGTTGAATCCAACAATGAGG	SIN3B	ENSG00000127511	-1.0281382631351483	[216,171]	[73,35]	-6	hSpCas9	negative selection	5440590
16841768	16841790	19	+	27760321	MOLM13	viability	GAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.5361714959878895	[1169,1077]	[641,262]	-3	hSpCas9	negative selection	5440591
16862904	16862926	19	-	27760321	MOLM13	viability	ATCGTCTGTCCACGAACCCTGG	SIN3B	ENSG00000127511	-0.7112068954555844	[713,610]	[158,285]	-4	hSpCas9	negative selection	5440592
16829418	16829441	19	+	27661255	K562	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.21292592744855537	[799,802]	[594,515]	-6	dCas9-KRAB	negative selection	5511095
16829815	16829838	19	+	27661255	K562	viability	GACCAGGTGAAGATCCGCTTTGG	SIN3B	ENSG00000127511	-0.004103833451630345	[1071,1156]	[899,874]	0	dCas9-KRAB	negative selection	5511096
16829409	16829432	19	-	27661255	K562	viability	GCGTGCGCCATGTCCGAAGTCGG	SIN3B	ENSG00000127511	-0.6166619844338621	[280,274]	[159,131]	-8	dCas9-KRAB	negative selection	5511097
16829807	16829830	19	-	27661255	K562	viability	GATCTTCACCTGGTCCAGATAGG	SIN3B	ENSG00000127511	-0.11355016376951177	[1377,1520]	[1151,996]	-4	dCas9-KRAB	negative selection	5511098
16829852	16829875	19	-	27661255	K562	viability	GATCTCCAGGAAGCCGTTGTAGG	SIN3B	ENSG00000127511	-0.006429340667095662	[413,503]	[434,302]	0	dCas9-KRAB	negative selection	5511099
16851515	16851538	19	-	27260156	BXPC3	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.5331682903343505	[235]	[268,341,456,371]	9	hSpCas9	negative selection	5570276
16831486	16831509	19	+	27260156	BXPC3	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.11926369048409735	[943]	[891,833,1003,905]	-3	hSpCas9	negative selection	5570277
16853103	16853126	19	-	27260156	BXPC3	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.24643004198032853	[603]	[492,543,508,589]	-5	hSpCas9	negative selection	5570278
16831540	16831563	19	+	27260156	BXPC3	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.018641184158614654	[656]	[512,690,606,945]	0	hSpCas9	negative selection	5634530
16851453	16851476	19	+	27260156	BXPC3	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.40339979901677214	[52]	[66,60,38,133]	8	hSpCas9	negative selection	5634531
16853095	16853118	19	+	27260156	BXPC3	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.0242471847347923	[189]	[91,130,100,59]	-9	hSpCas9	negative selection	5634532
16851515	16851538	19	-	27260156	A673	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.3453962844842551	[235]	[411,306,333,395]	7	hSpCas9	negative selection	5691527
16831486	16831509	19	+	27260156	A673	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.0955489943462906	[943]	[1337,1038,1236,1248]	2	hSpCas9	negative selection	5691528
16853103	16853126	19	-	27260156	A673	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.16731570922942804	[603]	[778,520,589,714]	-4	hSpCas9	negative selection	5691529
16831540	16831563	19	+	27260156	A673	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	0.0192073216883184	[656]	[801,820,746,827]	0	hSpCas9	negative selection	5755781
16851453	16851476	19	+	27260156	A673	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.2843785015910787	[52]	[77,52,135,40]	6	hSpCas9	negative selection	5755782
16853095	16853118	19	+	27260156	A673	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.7677567926466735	[189]	[160,114,119,143]	-9	hSpCas9	negative selection	5755783
16851515	16851538	19	-	27260156	A375	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.4855969219582178	[235]	[475,355,405,309]	7	hSpCas9	negative selection	5812778
16831486	16831509	19	+	27260156	A375	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.21606153335386058	[943]	[938,987,972,903]	-3	hSpCas9	negative selection	5812779
16853103	16853126	19	-	27260156	A375	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.7936480933155816	[603]	[386,430,399,410]	-7	hSpCas9	negative selection	5812780
16831540	16831563	19	+	27260156	A375	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.1436143118835298	[656]	[614,847,752,592]	-2	hSpCas9	negative selection	5877032
16851453	16851476	19	+	27260156	A375	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.4664552273922742	[52]	[121,23,124,64]	6	hSpCas9	negative selection	5877033
16853095	16853118	19	+	27260156	A375	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.5028907291696227	[189]	[102,161,202,157]	-6	hSpCas9	negative selection	5877034
16851515	16851538	19	-	27260156	COLO741	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.4591939385187155	[235]	[447,431,368]	8	hSpCas9	negative selection	5934029
16831486	16831509	19	+	27260156	COLO741	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.014947311891710169	[943]	[1263,1205,1119]	0	hSpCas9	negative selection	5934030
16853103	16853126	19	-	27260156	COLO741	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.20788518374211412	[603]	[715,664,628]	-4	hSpCas9	negative selection	5934031
16831540	16831563	19	+	27260156	COLO741	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.01783430592901386	[656]	[934,892,677]	0	hSpCas9	negative selection	5998283
16851453	16851476	19	+	27260156	COLO741	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.3690846285352878	[52]	[118,102,45]	7	hSpCas9	negative selection	5998284
16853095	16853118	19	+	27260156	COLO741	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.39303562818158677	[189]	[211,236,112]	-7	hSpCas9	negative selection	5998285
16851515	16851538	19	-	27260156	CAL120	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.8067887053388074	[235]	[463,583,485]	9	hSpCas9	negative selection	6055280
16831486	16831509	19	+	27260156	CAL120	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.1369581722973343	[943]	[1034,1068,1094]	-2	hSpCas9	negative selection	6055281
16853103	16853126	19	-	27260156	CAL120	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.45427851288904325	[603]	[602,350,696]	-6	hSpCas9	negative selection	6055282
16831540	16831563	19	+	27260156	CAL120	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	0.061525584424878765	[656]	[931,782,855]	0	hSpCas9	negative selection	6119534
16851453	16851476	19	+	27260156	CAL120	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.5569868746284223	[52]	[207,72,27]	8	hSpCas9	negative selection	6119535
16853095	16853118	19	+	27260156	CAL120	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.1960390444900981	[189]	[67,118,116]	-9	hSpCas9	negative selection	6119536
16851515	16851538	19	-	27260156	CADOES1	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.21524495951227296	[235]	[379,232,224,177]	3	hSpCas9	negative selection	6176531
16831486	16831509	19	+	27260156	CADOES1	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.029370843209739927	[943]	[977,741,905,959]	0	hSpCas9	negative selection	6176532
16853103	16853126	19	-	27260156	CADOES1	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.15598857457831058	[603]	[405,651,411,548]	-3	hSpCas9	negative selection	6176533
16831540	16831563	19	+	27260156	CADOES1	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	0.028497591090476004	[656]	[657,509,665,659]	0	hSpCas9	negative selection	6240785
16851453	16851476	19	+	27260156	CADOES1	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.40412564980478827	[52]	[25,61,25,34]	-6	hSpCas9	negative selection	6240786
16853095	16853118	19	+	27260156	CADOES1	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.831904361741957	[189]	[74,111,140,67]	-9	hSpCas9	negative selection	6240787
16851515	16851538	19	-	27260156	EWS502	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.5853030935671342	[235]	[360,256,419,474]	8	hSpCas9	negative selection	6297782
16831486	16831509	19	+	27260156	EWS502	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.1527038837803394	[943]	[1051,1134,996,1273]	2	hSpCas9	negative selection	6297783
16853103	16853126	19	-	27260156	EWS502	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.538465858534743	[603]	[343,526,449,447]	-7	hSpCas9	negative selection	6297784
16831540	16831563	19	+	27260156	EWS502	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.35255915946202554	[656]	[456,519,706,504]	-6	hSpCas9	negative selection	6362036
16851453	16851476	19	+	27260156	EWS502	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.6805399677658577	[52]	[59,60,77,170]	9	hSpCas9	negative selection	6362037
16853095	16853118	19	+	27260156	EWS502	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.8193674593237619	[189]	[106,134,123,87]	-8	hSpCas9	negative selection	6362038
16851515	16851538	19	-	27260156	EW8	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.1721288641599078	[235]	[343,201,147,192]	3	hSpCas9	negative selection	6419033
16831486	16831509	19	+	27260156	EW8	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.11959274120906149	[943]	[684,812,579,755]	-2	hSpCas9	negative selection	6419034
16853103	16853126	19	-	27260156	EW8	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.785560030401254	[603]	[315,307,282,231]	-8	hSpCas9	negative selection	6419035
16831540	16831563	19	+	27260156	EW8	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.053674531050587615	[656]	[568,838,352,324]	-1	hSpCas9	negative selection	6483287
16851453	16851476	19	+	27260156	EW8	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.09335017212991925	[52]	[72,61,14,18]	-2	hSpCas9	negative selection	6483288
16853095	16853118	19	+	27260156	EW8	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.0434493258674609	[189]	[74,84,72,65]	-9	hSpCas9	negative selection	6483289
16851515	16851538	19	-	27260156	CORL105	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.47481324638553934	[235]	[368,267,496,420]	8	hSpCas9	negative selection	6540284
16831486	16831509	19	+	27260156	CORL105	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.11670055889331432	[943]	[1224,924,1555,1148]	2	hSpCas9	negative selection	6540285
16853103	16853126	19	-	27260156	CORL105	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.3390839120862307	[603]	[605,537,615,486]	-6	hSpCas9	negative selection	6540286
16831540	16831563	19	+	27260156	CORL105	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.08230441211142864	[656]	[793,576,778,768]	-1	hSpCas9	negative selection	6604538
16851453	16851476	19	+	27260156	CORL105	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.7311032861932327	[52]	[108,89,181,43]	9	hSpCas9	negative selection	6604539
16853095	16853118	19	+	27260156	CORL105	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.8341902414976792	[189]	[122,88,177,117]	-9	hSpCas9	negative selection	6604540
16851515	16851538	19	-	27260156	HS294T	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.3241768427444467	[235]	[87,116,114,143]	4	hSpCas9	negative selection	6661535
16831486	16831509	19	+	27260156	HS294T	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.13078031685007319	[943]	[261,354,290,449]	-2	hSpCas9	negative selection	6661536
16853103	16853126	19	-	27260156	HS294T	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.4371993129055471	[603]	[167,163,125,243]	-6	hSpCas9	negative selection	6661537
16831540	16831563	19	+	27260156	HS294T	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.212242706943563	[656]	[192,128,245,332]	-3	hSpCas9	negative selection	6725789
16851453	16851476	19	+	27260156	HS294T	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.4741224528812902	[52]	[45,22,20,20]	6	hSpCas9	negative selection	6725790
16853095	16853118	19	+	27260156	HS294T	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.32181735783488463	[189]	[32,42,77,88]	-4	hSpCas9	negative selection	6725791
16851515	16851538	19	-	27260156	HCC44	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.23947124843413947	[235]	[343,268,398,270]	4	hSpCas9	negative selection	6782786
16831486	16831509	19	+	27260156	HCC44	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.10459423528313705	[943]	[1249,963,1371,1072]	1	hSpCas9	negative selection	6782787
16853103	16853126	19	-	27260156	HCC44	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.6514588988505282	[603]	[294,416,619,425]	-7	hSpCas9	negative selection	6782788
16831540	16831563	19	+	27260156	HCC44	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.18686081300736557	[656]	[784,482,818,585]	-3	hSpCas9	negative selection	6847040
16851453	16851476	19	+	27260156	HCC44	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.4611907837214515	[52]	[37,12,225,82]	7	hSpCas9	negative selection	6847041
16853095	16853118	19	+	27260156	HCC44	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.7188214946119569	[189]	[96,63,259,128]	-7	hSpCas9	negative selection	6847042
16851515	16851538	19	-	27260156	G402	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.2795308391189102	[235]	[335,332,356,366]	3	hSpCas9	negative selection	6904037
16831486	16831509	19	+	27260156	G402	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.728832843920816	[943]	[2235,2390,1892,1217]	8	hSpCas9	negative selection	6904038
16853103	16853126	19	-	27260156	G402	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	0.2821298752826686	[603]	[986,721,994,880]	3	hSpCas9	negative selection	6904039
16831540	16831563	19	+	27260156	G402	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	0.26820531874244036	[656]	[973,1321,765,824]	3	hSpCas9	negative selection	6968291
16851453	16851476	19	+	27260156	G402	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	1.0028575158638144	[52]	[2,403,51,59]	9	hSpCas9	negative selection	6968292
16853095	16853118	19	+	27260156	G402	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.5598213154251008	[189]	[426,107,65,67]	-6	hSpCas9	negative selection	6968293
16851515	16851538	19	-	27260156	L33	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.4977232159261358	[235]	[327,156,204,295]	8	hSpCas9	negative selection	7025288
16831486	16831509	19	+	27260156	L33	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.014832912299595602	[943]	[812,364,680,1030]	0	hSpCas9	negative selection	7025289
16853103	16853126	19	-	27260156	L33	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.28808969878536517	[603]	[590,199,298,421]	-6	hSpCas9	negative selection	7025290
16831540	16831563	19	+	27260156	L33	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.005288941022421445	[656]	[596,260,470,636]	0	hSpCas9	negative selection	7089542
16851453	16851476	19	+	27260156	L33	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.4223526334586083	[52]	[67,23,42,88]	8	hSpCas9	negative selection	7089543
16853095	16853118	19	+	27260156	L33	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.11415881247987869	[189]	[183,71,106,171]	-3	hSpCas9	negative selection	7089544
16851515	16851538	19	-	27260156	K562	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.36338876188753955	[235]	[343,191,361,189]	4	hSpCas9	negative selection	7146539
16831486	16831509	19	+	27260156	K562	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.5725517442855852	[943]	[660,365,332,853]	-6	hSpCas9	negative selection	7146540
16853103	16853126	19	-	27260156	K562	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-1.2459462800545833	[603]	[221,258,249,178]	-8	hSpCas9	negative selection	7146541
16831540	16831563	19	+	27260156	K562	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.2261929650837432	[656]	[405,602,495,485]	-3	hSpCas9	negative selection	7210793
16851453	16851476	19	+	27260156	K562	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.5515949993940299	[52]	[40,7,58,20]	-6	hSpCas9	negative selection	7210794
16853095	16853118	19	+	27260156	K562	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.757161350496971	[189]	[85,49,60,9]	-9	hSpCas9	negative selection	7210795
16851515	16851538	19	-	27260156	HT29	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.04183756474337408	[235]	[360,319,278,233]	0	hSpCas9	negative selection	7267790
16831486	16831509	19	+	27260156	HT29	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.22925462596889523	[943]	[1036,1253,938,736]	-4	hSpCas9	negative selection	7267791
16853103	16853126	19	-	27260156	HT29	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.9575523259216547	[603]	[389,575,313,261]	-8	hSpCas9	negative selection	7267792
16831540	16831563	19	+	27260156	HT29	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.3575015613934888	[656]	[707,541,691,554]	-6	hSpCas9	negative selection	7332044
16851453	16851476	19	+	27260156	HT29	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.36053333025213385	[52]	[48,131,77,73]	7	hSpCas9	negative selection	7332045
16853095	16853118	19	+	27260156	HT29	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.816144991724995	[189]	[80,185,120,135]	-8	hSpCas9	negative selection	7332046
16851515	16851538	19	-	27260156	MHHES1	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.29681495030804395	[235]	[357,543,221,223]	5	hSpCas9	negative selection	7389041
16831486	16831509	19	+	27260156	MHHES1	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.1625017016281265	[943]	[802,1088,1094,818]	-3	hSpCas9	negative selection	7389042
16853103	16853126	19	-	27260156	MHHES1	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.41759588323602215	[603]	[431,708,529,392]	-7	hSpCas9	negative selection	7389043
16831540	16831563	19	+	27260156	MHHES1	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.6133012225219712	[656]	[497,573,596,307]	-8	hSpCas9	negative selection	7453295
16851453	16851476	19	+	27260156	MHHES1	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.5732876800818834	[52]	[196,95,73,16]	8	hSpCas9	negative selection	7453296
16853095	16853118	19	+	27260156	MHHES1	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.5842526050132306	[189]	[219,41,167,137]	-8	hSpCas9	negative selection	7453297
16851515	16851538	19	-	27260156	MEWO	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.2971810568693234	[235]	[255,243,310]	6	hSpCas9	negative selection	7510292
16831486	16831509	19	+	27260156	MEWO	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.12696318086890168	[943]	[1119,690,675]	-3	hSpCas9	negative selection	7510293
16853103	16853126	19	-	27260156	MEWO	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.10870058790330045	[603]	[583,461,537]	-2	hSpCas9	negative selection	7510294
16831540	16831563	19	+	27260156	MEWO	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.08607197850770104	[656]	[519,706,497]	-2	hSpCas9	negative selection	7574546
16851453	16851476	19	+	27260156	MEWO	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.34837989550745974	[52]	[86,61,44]	7	hSpCas9	negative selection	7574547
16853095	16853118	19	+	27260156	MEWO	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.15157669194679202	[189]	[138,154,181]	-3	hSpCas9	negative selection	7574548
16851515	16851538	19	-	27260156	LNCAPCLONEFGC	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.35243565493347273	[235]	[266,274,275,273]	5	hSpCas9	negative selection	7631543
16831486	16831509	19	+	27260156	LNCAPCLONEFGC	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.11262970019469465	[943]	[612,828,911,827]	-2	hSpCas9	negative selection	7631544
16853103	16853126	19	-	27260156	LNCAPCLONEFGC	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.8533038098964401	[603]	[270,290,372,287]	-8	hSpCas9	negative selection	7631545
16831540	16831563	19	+	27260156	LNCAPCLONEFGC	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.2354208062840292	[656]	[461,494,583,493]	-4	hSpCas9	negative selection	7695797
16851453	16851476	19	+	27260156	LNCAPCLONEFGC	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.2147381159981081	[52]	[22,48,72,24]	-3	hSpCas9	negative selection	7695798
16853095	16853118	19	+	27260156	LNCAPCLONEFGC	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.1395415029098697	[189]	[80,63,75,91]	-9	hSpCas9	negative selection	7695799
16851515	16851538	19	-	27260156	PANC0327	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	1.0155527344733026	[235]	[571,626,279,201]	9	hSpCas9	negative selection	7752794
16831486	16831509	19	+	27260156	PANC0327	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.11607898921755999	[943]	[1076,773,819,994]	1	hSpCas9	negative selection	7752795
16853103	16853126	19	-	27260156	PANC0327	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.8492361297520822	[603]	[448,210,371,182]	-8	hSpCas9	negative selection	7752796
16831540	16831563	19	+	27260156	PANC0327	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.1822310359538547	[656]	[522,240,892,436]	-3	hSpCas9	negative selection	7817048
16851453	16851476	19	+	27260156	PANC0327	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.5753244438856586	[52]	[73,6,14,36]	-7	hSpCas9	negative selection	7817049
16853095	16853118	19	+	27260156	PANC0327	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.1706392842754878	[189]	[243,114,143,108]	-3	hSpCas9	negative selection	7817050
16851515	16851538	19	-	27260156	NCIH2009	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.47473561684005183	[235]	[505,474,401]	6	hSpCas9	negative selection	7874045
16831486	16831509	19	+	27260156	NCIH2009	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.09624013528593933	[943]	[1473,1001,1274]	-1	hSpCas9	negative selection	7874046
16853103	16853126	19	-	27260156	NCIH2009	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.6372185379016655	[603]	[561,522,545]	-7	hSpCas9	negative selection	7874047
16831540	16831563	19	+	27260156	NCIH2009	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.36659333480404577	[656]	[730,900,502]	-5	hSpCas9	negative selection	7938299
16851453	16851476	19	+	27260156	NCIH2009	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.46136216736861346	[52]	[150,67,96]	6	hSpCas9	negative selection	7938300
16853095	16853118	19	+	27260156	NCIH2009	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.9427359098277557	[189]	[247,71,116]	-8	hSpCas9	negative selection	7938301
16851515	16851538	19	-	27260156	NCIH1373	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.2908047284978006	[235]	[537,322,288,43]	3	hSpCas9	negative selection	7995296
16831486	16831509	19	+	27260156	NCIH1373	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.13963340897579068	[943]	[1093,1307,1183,271]	1	hSpCas9	negative selection	7995297
16853103	16853126	19	-	27260156	NCIH1373	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.32283690706888896	[603]	[695,205,540,208]	-3	hSpCas9	negative selection	7995298
16831540	16831563	19	+	27260156	NCIH1373	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.7090925652044466	[656]	[426,191,556,172]	-6	hSpCas9	negative selection	8059550
16851453	16851476	19	+	27260156	NCIH1373	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	1.120689010661025	[52]	[190,156,39,35]	9	hSpCas9	negative selection	8059551
16853095	16853118	19	+	27260156	NCIH1373	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.5093788694861074	[189]	[15,133,88,10]	-9	hSpCas9	negative selection	8059552
16851515	16851538	19	-	27260156	PATU8902	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	-0.5211402736306965	[235]	[197,313,243,144]	-5	hSpCas9	negative selection	8116547
16831486	16831509	19	+	27260156	PATU8902	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.12894096568489877	[943]	[1378,1204,775,1594]	-1	hSpCas9	negative selection	8116548
16853103	16853126	19	-	27260156	PATU8902	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.6330624997290026	[603]	[788,958,229,228]	-6	hSpCas9	negative selection	8116549
16831540	16831563	19	+	27260156	PATU8902	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-1.0662765486108132	[656]	[497,555,271,463]	-7	hSpCas9	negative selection	8180801
16851453	16851476	19	+	27260156	PATU8902	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.3422925340123504	[52]	[85,25,175,59]	3	hSpCas9	negative selection	8180802
16853095	16853118	19	+	27260156	PATU8902	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.803008830953285	[189]	[31,159,89,9]	-8	hSpCas9	negative selection	8180803
16851515	16851538	19	-	27260156	PANC1	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.21051844523424823	[235]	[254,220,240,216]	3	hSpCas9	negative selection	8237798
16831486	16831509	19	+	27260156	PANC1	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	0.03142275442326481	[943]	[602,1128,745,879]	0	hSpCas9	negative selection	8237799
16853103	16853126	19	-	27260156	PANC1	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-1.0812771842476445	[603]	[282,316,225,175]	-8	hSpCas9	negative selection	8237800
16831540	16831563	19	+	27260156	PANC1	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.14802687591789276	[656]	[522,388,502,576]	-2	hSpCas9	negative selection	8302052
16851453	16851476	19	+	27260156	PANC1	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.753573435464566	[52]	[98,51,84,65]	9	hSpCas9	negative selection	8302053
16853095	16853118	19	+	27260156	PANC1	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.347972810422128	[189]	[40,96,82,44]	-9	hSpCas9	negative selection	8302054
16851515	16851538	19	-	27260156	PANC0813	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.14935357281692652	[235]	[392,314,327,206]	2	hSpCas9	negative selection	8359049
16831486	16831509	19	+	27260156	PANC0813	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.27491746467889844	[943]	[944,749,1042,928]	-4	hSpCas9	negative selection	8359050
16853103	16853126	19	-	27260156	PANC0813	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-1.243129034458277	[603]	[347,365,217,271]	-9	hSpCas9	negative selection	8359051
16831540	16831563	19	+	27260156	PANC0813	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.5545965263149377	[656]	[531,462,584,521]	-7	hSpCas9	negative selection	8423303
16851453	16851476	19	+	27260156	PANC0813	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.556370784923212	[52]	[104,68,26,161]	8	hSpCas9	negative selection	8423304
16853095	16853118	19	+	27260156	PANC0813	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.6435116381054935	[189]	[45,66,91,77]	-9	hSpCas9	negative selection	8423305
16851515	16851538	19	-	27260156	RDES	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.2854671487188094	[235]	[240,306,383,418]	4	hSpCas9	negative selection	8480300
16831486	16831509	19	+	27260156	RDES	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.24076888446364042	[943]	[715,831,1212,955]	-4	hSpCas9	negative selection	8480301
16853103	16853126	19	-	27260156	RDES	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.6920823360818642	[603]	[350,386,389,628]	-8	hSpCas9	negative selection	8480302
16831540	16831563	19	+	27260156	RDES	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.39885318801814373	[656]	[485,567,553,704]	-6	hSpCas9	negative selection	8544554
16851453	16851476	19	+	27260156	RDES	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.38924198666404575	[52]	[79,49,86,106]	6	hSpCas9	negative selection	8544555
16853095	16853118	19	+	27260156	RDES	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.1477302038216153	[189]	[71,76,107,150]	-9	hSpCas9	negative selection	8544556
16851515	16851538	19	-	27260156	PC3	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.25890603845742033	[235]	[139,310,492,302]	5	hSpCas9	negative selection	8601551
16831486	16831509	19	+	27260156	PC3	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.018334296372514047	[943]	[563,1165,1278,897]	0	hSpCas9	negative selection	8601552
16853103	16853126	19	-	27260156	PC3	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.255818241812394	[603]	[245,516,1021,506]	-5	hSpCas9	negative selection	8601553
16831540	16831563	19	+	27260156	PC3	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	0.07296152789850818	[656]	[467,725,944,739]	1	hSpCas9	negative selection	8665805
16851453	16851476	19	+	27260156	PC3	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.07432210603221456	[52]	[34,48,66,80]	1	hSpCas9	negative selection	8665806
16853095	16853118	19	+	27260156	PC3	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.8213953917894217	[189]	[62,113,107,154]	-9	hSpCas9	negative selection	8665807
16851515	16851538	19	-	27260156	PATU8988T	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	-0.07376664631000796	[235]	[183,359,163,168]	-1	hSpCas9	negative selection	8722802
16831486	16831509	19	+	27260156	PATU8988T	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.269040305240985	[943]	[516,823,685,1029]	-4	hSpCas9	negative selection	8722803
16853103	16853126	19	-	27260156	PATU8988T	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-1.253132820320669	[603]	[256,288,185,252]	-9	hSpCas9	negative selection	8722804
16831540	16831563	19	+	27260156	PATU8988T	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.5274549431626363	[656]	[340,639,325,477]	-7	hSpCas9	negative selection	8787056
16851453	16851476	19	+	27260156	PATU8988T	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.4449597319796772	[52]	[21,30,83,9]	-6	hSpCas9	negative selection	8787057
16853095	16853118	19	+	27260156	PATU8988T	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.30053694386959506	[189]	[160,62,50,328]	-5	hSpCas9	negative selection	8787058
16851515	16851538	19	-	27260156	T47D	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.3198729526216031	[235]	[355,325,329,362]	6	hSpCas9	negative selection	8844053
16831486	16831509	19	+	27260156	T47D	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.14868667503224986	[943]	[1004,916,1046,1004]	-3	hSpCas9	negative selection	8844054
16853103	16853126	19	-	27260156	T47D	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.47086199574080095	[603]	[526,437,561,508]	-7	hSpCas9	negative selection	8844055
16831540	16831563	19	+	27260156	T47D	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.23878146781747264	[656]	[611,547,643,803]	-5	hSpCas9	negative selection	8908307
16851453	16851476	19	+	27260156	T47D	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.06436708710720485	[52]	[38,33,75,89]	-1	hSpCas9	negative selection	8908308
16853095	16853118	19	+	27260156	T47D	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.5920881986267803	[189]	[163,137,164,119]	-8	hSpCas9	negative selection	8908309
16851515	16851538	19	-	27260156	SU8686	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.5040511500998306	[235]	[314,266,266,513]	8	hSpCas9	negative selection	8965304
16831486	16831509	19	+	27260156	SU8686	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.06289477874311877	[943]	[728,758,964,1214]	-1	hSpCas9	negative selection	8965305
16853103	16853126	19	-	27260156	SU8686	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.38623938079913767	[603]	[382,402,493,586]	-6	hSpCas9	negative selection	8965306
16831540	16831563	19	+	27260156	SU8686	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.5904142065849334	[656]	[472,395,388,474]	-7	hSpCas9	negative selection	9029558
16851453	16851476	19	+	27260156	SU8686	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.9858247401791309	[52]	[60,154,89,107]	9	hSpCas9	negative selection	9029559
16853095	16853118	19	+	27260156	SU8686	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.027351623801814	[189]	[69,75,79,157]	-8	hSpCas9	negative selection	9029560
16851515	16851538	19	-	27260156	SKES1	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.7060147980278588	[235]	[490,299,350,393]	9	hSpCas9	negative selection	9086555
16831486	16831509	19	+	27260156	SKES1	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.06206836822170736	[943]	[1141,1032,918,590]	-1	hSpCas9	negative selection	9086556
16853103	16853126	19	-	27260156	SKES1	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.3301682534952137	[603]	[564,566,361,445]	-6	hSpCas9	negative selection	9086557
16831540	16831563	19	+	27260156	SKES1	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.1571708480671825	[656]	[531,619,635,555]	-3	hSpCas9	negative selection	9150809
16851453	16851476	19	+	27260156	SKES1	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	0.31274875276833436	[52]	[125,59,25,58]	6	hSpCas9	negative selection	9150810
16853095	16853118	19	+	27260156	SKES1	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.41954286059775736	[189]	[145,136,136,144]	-7	hSpCas9	negative selection	9150811
16851515	16851538	19	-	27260156	TOV112D	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.4997915632953482	[235]	[375,383,253,337]	8	hSpCas9	negative selection	9207806
16831486	16831509	19	+	27260156	TOV112D	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.03329202743534165	[943]	[1208,957,872,692]	0	hSpCas9	negative selection	9207807
16853103	16853126	19	-	27260156	TOV112D	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.705282695108207	[603]	[297,471,354,376]	-8	hSpCas9	negative selection	9207808
16831540	16831563	19	+	27260156	TOV112D	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.1622189323422476	[656]	[512,669,592,588]	-3	hSpCas9	negative selection	9272060
16851453	16851476	19	+	27260156	TOV112D	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-1.150806078560291	[52]	[46,16,13,17]	-9	hSpCas9	negative selection	9272061
16853095	16853118	19	+	27260156	TOV112D	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-1.0698768843268884	[189]	[112,136,80,45]	-9	hSpCas9	negative selection	9272062
16851515	16851538	19	-	27260156	TC71	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.2444449497699992	[235]	[257,273,300,370]	6	hSpCas9	negative selection	9329057
16831486	16831509	19	+	27260156	TC71	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.17089753761390503	[943]	[794,770,998,1037]	-4	hSpCas9	negative selection	9329058
16853103	16853126	19	-	27260156	TC71	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.09498932549359446	[603]	[533,648,430,831]	-2	hSpCas9	negative selection	9329059
16831540	16831563	19	+	27260156	TC71	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	0.025394244575809743	[656]	[566,790,741,772]	0	hSpCas9	negative selection	9393311
16851453	16851476	19	+	27260156	TC71	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.1715864731872081	[52]	[76,27,58,35]	-4	hSpCas9	negative selection	9393312
16853095	16853118	19	+	27260156	TC71	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.3956627898606504	[189]	[122,144,191,158]	-8	hSpCas9	negative selection	9393313
16851515	16851538	19	-	27260156	TC32	viability	TACCTTGGCGGGTGCAGACACGG	SIN3B	ENSG00000127511	0.18812913297426515	[235]	[263,195,372,199]	3	hSpCas9	negative selection	9450308
16831486	16831509	19	+	27260156	TC32	viability	TCTTCTAGCATCGATACTCCTGG	SIN3B	ENSG00000127511	-0.0565444843713413	[943]	[729,619,998,1159]	-1	hSpCas9	negative selection	9450309
16853103	16853126	19	-	27260156	TC32	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.34694871064439725	[603]	[427,353,540,490]	-6	hSpCas9	negative selection	9450310
16831540	16831563	19	+	27260156	TC32	viability	GAGCACCCTGACCTCATTGTTGG	SIN3B	ENSG00000127511	-0.1854798656059249	[656]	[395,513,767,527]	-3	hSpCas9	negative selection	9514562
16851453	16851476	19	+	27260156	TC32	viability	GAACGAGCACGACAAGACCCCGG	SIN3B	ENSG00000127511	-0.47282759233551497	[52]	[28,2,31,93]	-7	hSpCas9	negative selection	9514563
16853095	16853118	19	+	27260156	TC32	viability	AGACCTGTCCATCGCTGCAGTGG	SIN3B	ENSG00000127511	-0.9159636514512255	[189]	[90,123,52,84]	-9	hSpCas9	negative selection	9514564
16829402	16829425	19	+	27869803	HPAFII	viability after 27 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.22378386319935628	[928]	[895,298,NaN]	1	hSpCas9	negative selection	9566204
16829799	16829822	19	+	27869803	HPAFII	viability after 27 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	0.08198544982449074	[741]	[587,266,NaN]	0	hSpCas9	negative selection	9566205
16831626	16831649	19	+	27869803	HPAFII	viability after 27 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.4632666143586601	[147]	[181,44,NaN]	4	hSpCas9	negative selection	9566206
16841766	16841789	19	+	27869803	HPAFII	viability after 27 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.605033575416711	[264]	[248,180,NaN]	5	hSpCas9	negative selection	9566207
16846997	16847020	19	-	27869803	HPAFII	viability after 27 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	1.3921999825051077	[233]	[419,241,NaN]	9	hSpCas9	negative selection	9566208
16851513	16851536	19	-	27869803	HPAFII	viability after 27 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.09912373421639872	[287]	[111,203,NaN]	0	hSpCas9	negative selection	9566209
16829402	16829425	19	+	27869803	HPAFII	viability after 15 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	-0.015007690517188088	[928]	[1600,606,NaN]	0	hSpCas9	negative selection	9648653
16829799	16829822	19	+	27869803	HPAFII	viability after 15 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.0352826244601927	[741]	[1305,449,NaN]	0	hSpCas9	negative selection	9648654
16831626	16831649	19	+	27869803	HPAFII	viability after 15 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.7933595333371872	[147]	[287,267,NaN]	8	hSpCas9	negative selection	9648655
16841766	16841789	19	+	27869803	HPAFII	viability after 15 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	-0.18016856235143786	[264]	[259,245,NaN]	-2	hSpCas9	negative selection	9648656
16846997	16847020	19	-	27869803	HPAFII	viability after 15 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.6442670002875377	[233]	[672,218,NaN]	7	hSpCas9	negative selection	9648657
16851513	16851536	19	-	27869803	HPAFII	viability after 15 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	-0.1766767614920891	[287]	[234,297,NaN]	-2	hSpCas9	negative selection	9648658
16829402	16829425	19	+	27869803	ASPC1	viability after 36 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	-0.38111797811207704	[2670]	[1014,926,330]	-4	hSpCas9	negative selection	9731102
16829799	16829822	19	+	27869803	ASPC1	viability after 36 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.4438550400795631	[1929]	[482,276,671]	-4	hSpCas9	negative selection	9731103
16831626	16831649	19	+	27869803	ASPC1	viability after 36 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.4435481802998636	[478]	[385,187,144]	4	hSpCas9	negative selection	9731104
16841766	16841789	19	+	27869803	ASPC1	viability after 36 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.2912174250807097	[566]	[489,183,111]	3	hSpCas9	negative selection	9731105
16846997	16847020	19	-	27869803	ASPC1	viability after 36 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.3775207894101706	[461]	[298,252,109]	4	hSpCas9	negative selection	9731106
16851513	16851536	19	-	27869803	ASPC1	viability after 36 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	-0.06901593704468095	[724]	[203,230,272]	0	hSpCas9	negative selection	9731107
16829402	16829425	19	+	27869803	PATU8988S	viability after 35 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	-0.25160169452407644	[2352]	[799,791,NaN]	-3	hSpCas9	negative selection	9813551
16829799	16829822	19	+	27869803	PATU8988S	viability after 35 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.5059446368523255	[1583]	[557,339,NaN]	-5	hSpCas9	negative selection	9813552
16831626	16831649	19	+	27869803	PATU8988S	viability after 35 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.19715794743334877	[427]	[249,144,NaN]	2	hSpCas9	negative selection	9813553
16841766	16841789	19	+	27869803	PATU8988S	viability after 35 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	-0.43236296114482575	[398]	[155,81,NaN]	-4	hSpCas9	negative selection	9813554
16846997	16847020	19	-	27869803	PATU8988S	viability after 35 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.29203876970951737	[332]	[254,72,NaN]	3	hSpCas9	negative selection	9813555
16851513	16851536	19	-	27869803	PATU8988S	viability after 35 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	-0.09160351725310456	[856]	[289,357,NaN]	-1	hSpCas9	negative selection	9813556
16829402	16829425	19	+	27869803	PATU8988S	viability after 31 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	-0.23698831682578514	[2352]	[763,836,NaN]	-3	hSpCas9	negative selection	9896000
16829799	16829822	19	+	27869803	PATU8988S	viability after 31 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.734998007179172	[1583]	[393,360,NaN]	-7	hSpCas9	negative selection	9896001
16831626	16831649	19	+	27869803	PATU8988S	viability after 31 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	-0.32496541120509514	[427]	[148,119,NaN]	-4	hSpCas9	negative selection	9896002
16841766	16841789	19	+	27869803	PATU8988S	viability after 31 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	-0.6402302941334908	[398]	[98,105,NaN]	-6	hSpCas9	negative selection	9896003
16846997	16847020	19	-	27869803	PATU8988S	viability after 31 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	0.14399896370721332	[332]	[140,153,NaN]	1	hSpCas9	negative selection	9896004
16851513	16851536	19	-	27869803	PATU8988S	viability after 31 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	-0.04621424783499617	[856]	[282,391,NaN]	0	hSpCas9	negative selection	9896005
16829402	16829425	19	+	27869803	HPAFII	viability after 35 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.5896920992252708	[928]	[957,425,NaN]	4	hSpCas9	negative selection	9978449
16829799	16829822	19	+	27869803	HPAFII	viability after 35 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	0.18259326357908212	[741]	[589,241,NaN]	1	hSpCas9	negative selection	9978450
16831626	16831649	19	+	27869803	HPAFII	viability after 35 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	1.7323622811169508	[147]	[390,88,NaN]	9	hSpCas9	negative selection	9978451
16841766	16841789	19	+	27869803	HPAFII	viability after 35 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.1094330054524653	[264]	[187,95,NaN]	0	hSpCas9	negative selection	9978452
16846997	16847020	19	-	27869803	HPAFII	viability after 35 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	1.4927964990244083	[233]	[410,245,NaN]	8	hSpCas9	negative selection	9978453
16851513	16851536	19	-	27869803	HPAFII	viability after 35 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.06540845092784728	[287]	[97,213,NaN]	0	hSpCas9	negative selection	9978454
16829402	16829425	19	+	27869803	HPAFII	viability after 31 days	CGCAGCTCCGACTTCGGACATGG	SIN3B	ENSG00000127511	0.20358225262028085	[928]	[742,444,NaN]	1	hSpCas9	negative selection	10060898
16829799	16829822	19	+	27869803	HPAFII	viability after 31 days	CGCCCTCACCTATCTGGACCAGG	SIN3B	ENSG00000127511	-0.036365220559289924	[741]	[518,282,NaN]	0	hSpCas9	negative selection	10060899
16831626	16831649	19	+	27869803	HPAFII	viability after 31 days	ACAGTCGCCTCTGACAAGCCAGG	SIN3B	ENSG00000127511	0.897846609208317	[147]	[249,50,NaN]	6	hSpCas9	negative selection	10060900
16841766	16841789	19	+	27869803	HPAFII	viability after 31 days	AGGAGAATTCGCACAACCACGGG	SIN3B	ENSG00000127511	0.6223663946359959	[264]	[316,132,NaN]	4	hSpCas9	negative selection	10060901
16846997	16847020	19	-	27869803	HPAFII	viability after 31 days	TCTTCAGACATGCCTCGGAATGG	SIN3B	ENSG00000127511	1.5013894401239725	[233]	[478,254,NaN]	9	hSpCas9	negative selection	10060902
16851513	16851536	19	-	27869803	HPAFII	viability after 31 days	CCTTGGCGGGTGCAGACACGGGG	SIN3B	ENSG00000127511	0.10792869521490331	[287]	[155,193,NaN]	0	hSpCas9	negative selection	10060903
16829418	16829441	19	+	28162770	P31FUJ	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.5703031032222021	[162]	[128]	-5	hSpCas9	negative selection	10234372
16862958	16862981	19	+	28162770	P31FUJ	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.038154773560834854	[359]	[411]	0	hSpCas9	negative selection	10234373
16829876	16829899	19	+	28162770	P31FUJ	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	-0.544263300250672	[102]	[82]	-4	hSpCas9	negative selection	10234374
16841767	16841790	19	+	28162770	P31FUJ	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.5907510747479181	[290]	[514]	6	hSpCas9	negative selection	10234375
16841821	16841844	19	+	28162770	P31FUJ	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.29265928455811574	[131]	[189]	3	hSpCas9	negative selection	10234376
16846969	16846992	19	+	28162770	P31FUJ	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-0.6387945640902155	[105]	[79]	-5	hSpCas9	negative selection	10234377
16847033	16847056	19	+	28162770	P31FUJ	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.35932008787964365	[468]	[706]	4	hSpCas9	negative selection	10234378
16851499	16851522	19	-	28162770	P31FUJ	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	-0.6631064603465329	[189]	[140]	-5	hSpCas9	negative selection	10234379
16853103	16853126	19	-	28162770	P31FUJ	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	0.3028927513900812	[555]	[805]	3	hSpCas9	negative selection	10234380
16854145	16854168	19	-	28162770	P31FUJ	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-0.33233787796529296	[194]	[181]	-3	hSpCas9	negative selection	10234381
16829418	16829441	19	+	28162770	TF1	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	NaN	[NaN]	[108]	1	hSpCas9	negative selection	10403738
16862958	16862981	19	+	28162770	TF1	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	NaN	[NaN]	[238]	1	hSpCas9	negative selection	10403739
16829876	16829899	19	+	28162770	TF1	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10403740
16841767	16841790	19	+	28162770	TF1	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10403741
16841821	16841844	19	+	28162770	TF1	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10403742
16846969	16846992	19	+	28162770	TF1	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10403743
16847033	16847056	19	+	28162770	TF1	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	NaN	[NaN]	[535]	1	hSpCas9	negative selection	10403744
16851499	16851522	19	-	28162770	TF1	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10403745
16853103	16853126	19	-	28162770	TF1	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	NaN	[NaN]	[126]	1	hSpCas9	negative selection	10403746
16854145	16854168	19	-	28162770	TF1	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10403747
16829418	16829441	19	+	28162770	SKM1	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	0.6124011261237695	[36]	[99]	6	hSpCas9	negative selection	10573104
16862958	16862981	19	+	28162770	SKM1	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.14392979290936792	[69]	[111]	-1	hSpCas9	negative selection	10573105
16829876	16829899	19	+	28162770	SKM1	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	0.056007777599384134	[36]	[67]	0	hSpCas9	negative selection	10573106
16841767	16841790	19	+	28162770	SKM1	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.16405911102012072	[103]	[205]	1	hSpCas9	negative selection	10573107
16841821	16841844	19	+	28162770	SKM1	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.47607965491098914	[60]	[149]	4	hSpCas9	negative selection	10573108
16846969	16846992	19	+	28162770	SKM1	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-0.13012399338433733	[38]	[62]	-1	hSpCas9	negative selection	10573109
16847033	16847056	19	+	28162770	SKM1	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.46381610345607627	[88]	[216]	4	hSpCas9	negative selection	10573110
16851499	16851522	19	-	28162770	SKM1	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	1.853869298897361	[40]	[261]	9	hSpCas9	negative selection	10573111
16853103	16853126	19	-	28162770	SKM1	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	0.34400825341692354	[122]	[275]	3	hSpCas9	negative selection	10573112
16854145	16854168	19	-	28162770	SKM1	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	1.1121103663215375	[27]	[106]	8	hSpCas9	negative selection	10573113
16829418	16829441	19	+	28162770	SKM1	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	0.6124011261237695	[36]	[99]	6	hSpCas9	negative selection	10742470
16862958	16862981	19	+	28162770	SKM1	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.14392979290936792	[69]	[111]	-1	hSpCas9	negative selection	10742471
16829876	16829899	19	+	28162770	SKM1	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	0.056007777599384134	[36]	[67]	0	hSpCas9	negative selection	10742472
16841767	16841790	19	+	28162770	SKM1	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.16405911102012072	[103]	[205]	1	hSpCas9	negative selection	10742473
16841821	16841844	19	+	28162770	SKM1	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.47607965491098914	[60]	[149]	4	hSpCas9	negative selection	10742474
16846969	16846992	19	+	28162770	SKM1	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-0.13012399338433733	[38]	[62]	-1	hSpCas9	negative selection	10742475
16847033	16847056	19	+	28162770	SKM1	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.46381610345607627	[88]	[216]	4	hSpCas9	negative selection	10742476
16851499	16851522	19	-	28162770	SKM1	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	1.853869298897361	[40]	[261]	9	hSpCas9	negative selection	10742477
16853103	16853126	19	-	28162770	SKM1	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	0.34400825341692354	[122]	[275]	3	hSpCas9	negative selection	10742478
16854145	16854168	19	-	28162770	SKM1	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	1.1121103663215375	[27]	[106]	8	hSpCas9	negative selection	10742479
16829418	16829441	19	+	28162770	PL21	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.34123361768415345	[162]	[55]	-2	hSpCas9	negative selection	10911836
16862958	16862981	19	+	28162770	PL21	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	0.014784572477401725	[281]	[123]	0	hSpCas9	negative selection	10911837
16829876	16829899	19	+	28162770	PL21	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	-0.8873232267610193	[101]	[23]	-6	hSpCas9	negative selection	10911838
16841767	16841790	19	+	28162770	PL21	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.8233958999714689	[308]	[75]	-5	hSpCas9	negative selection	10911839
16841821	16841844	19	+	28162770	PL21	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	-1.3783095792731619	[220]	[36]	-7	hSpCas9	negative selection	10911840
16846969	16846992	19	+	28162770	PL21	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-1.384822886231836	[131]	[21]	-7	hSpCas9	negative selection	10911841
16847033	16847056	19	+	28162770	PL21	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	-0.5256854220716854	[343]	[103]	-4	hSpCas9	negative selection	10911842
16851499	16851522	19	-	28162770	PL21	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	-0.3417541643399502	[98]	[33]	-2	hSpCas9	negative selection	10911843
16853103	16853126	19	-	28162770	PL21	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-2.350607170893923	[374]	[31]	-8	hSpCas9	negative selection	10911844
16854145	16854168	19	-	28162770	PL21	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-3.1921778082894403	[146]	[6]	-9	hSpCas9	negative selection	10911845
16829418	16829441	19	+	28162770	P31FUJ	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.5703031032222021	[162]	[128]	-5	hSpCas9	negative selection	11081202
16862958	16862981	19	+	28162770	P31FUJ	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.038154773560834854	[359]	[411]	0	hSpCas9	negative selection	11081203
16829876	16829899	19	+	28162770	P31FUJ	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	-0.544263300250672	[102]	[82]	-4	hSpCas9	negative selection	11081204
16841767	16841790	19	+	28162770	P31FUJ	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.5907510747479181	[290]	[514]	6	hSpCas9	negative selection	11081205
16841821	16841844	19	+	28162770	P31FUJ	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.29265928455811574	[131]	[189]	3	hSpCas9	negative selection	11081206
16846969	16846992	19	+	28162770	P31FUJ	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-0.6387945640902155	[105]	[79]	-5	hSpCas9	negative selection	11081207
16847033	16847056	19	+	28162770	P31FUJ	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.35932008787964365	[468]	[706]	4	hSpCas9	negative selection	11081208
16851499	16851522	19	-	28162770	P31FUJ	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	-0.6631064603465329	[189]	[140]	-5	hSpCas9	negative selection	11081209
16853103	16853126	19	-	28162770	P31FUJ	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	0.3028927513900812	[555]	[805]	3	hSpCas9	negative selection	11081210
16854145	16854168	19	-	28162770	P31FUJ	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-0.33233787796529296	[194]	[181]	-3	hSpCas9	negative selection	11081211
16829418	16829441	19	+	28162770	OCIAML5	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	0.15820176458983015	[69]	[140]	1	hSpCas9	negative selection	11250568
16862958	16862981	19	+	28162770	OCIAML5	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	0.5831488103524773	[141]	[383]	5	hSpCas9	negative selection	11250569
16829876	16829899	19	+	28162770	OCIAML5	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	0.6031280548868294	[61]	[169]	5	hSpCas9	negative selection	11250570
16841767	16841790	19	+	28162770	OCIAML5	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.18640757695063875	[147]	[303]	1	hSpCas9	negative selection	11250571
16841821	16841844	19	+	28162770	OCIAML5	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.01270604844177975	[94]	[172]	0	hSpCas9	negative selection	11250572
16846969	16846992	19	+	28162770	OCIAML5	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-0.5099605940390042	[70]	[89]	-4	hSpCas9	negative selection	11250573
16847033	16847056	19	+	28162770	OCIAML5	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.023944711860549805	[254]	[467]	0	hSpCas9	negative selection	11250574
16851499	16851522	19	-	28162770	OCIAML5	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	-0.726535688780138	[54]	[59]	-5	hSpCas9	negative selection	11250575
16853103	16853126	19	-	28162770	OCIAML5	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-0.8076724515055436	[319]	[329]	-5	hSpCas9	negative selection	11250576
16854145	16854168	19	-	28162770	OCIAML5	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-1.2146366502487054	[71]	[55]	-6	hSpCas9	negative selection	11250577
16829418	16829441	19	+	28162770	EOL1	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.9110654105285829	[231]	[64]	-6	hSpCas9	negative selection	11419934
16862958	16862981	19	+	28162770	EOL1	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.41542677873428124	[361]	[142]	-3	hSpCas9	negative selection	11419935
16829876	16829899	19	+	28162770	EOL1	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	-1.2576555596502146	[176]	[38]	-7	hSpCas9	negative selection	11419936
16841767	16841790	19	+	28162770	EOL1	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.20638309825591405	[656]	[299]	-1	hSpCas9	negative selection	11419937
16841821	16841844	19	+	28162770	EOL1	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	-0.2453772298717778	[287]	[127]	-2	hSpCas9	negative selection	11419938
16846969	16846992	19	+	28162770	EOL1	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-1.2129557521794005	[241]	[54]	-7	hSpCas9	negative selection	11419939
16847033	16847056	19	+	28162770	EOL1	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	-0.7456044702458652	[435]	[136]	-5	hSpCas9	negative selection	11419940
16851499	16851522	19	-	28162770	EOL1	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	0.4795155319938535	[161]	[118]	4	hSpCas9	negative selection	11419941
16853103	16853126	19	-	28162770	EOL1	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-1.7199157408992833	[593]	[94]	-8	hSpCas9	negative selection	11419942
16854145	16854168	19	-	28162770	EOL1	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-2.1029329648515724	[211]	[25]	-8	hSpCas9	negative selection	11419943
16829418	16829441	19	+	28162770	MOLM13	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.8701583787060605	[224]	[88]	-5	hSpCas9	negative selection	11589300
16862958	16862981	19	+	28162770	MOLM13	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.11910080052355976	[355]	[236]	0	hSpCas9	negative selection	11589301
16829876	16829899	19	+	28162770	MOLM13	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	0.4786157881376373	[133]	[134]	3	hSpCas9	negative selection	11589302
16841767	16841790	19	+	28162770	MOLM13	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.3927149910878037	[452]	[429]	3	hSpCas9	negative selection	11589303
16841821	16841844	19	+	28162770	MOLM13	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.11155125587138519	[296]	[231]	0	hSpCas9	negative selection	11589304
16846969	16846992	19	+	28162770	MOLM13	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	0.02790552513550404	[174]	[128]	0	hSpCas9	negative selection	11589305
16847033	16847056	19	+	28162770	MOLM13	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.3074247093513325	[588]	[526]	2	hSpCas9	negative selection	11589306
16851499	16851522	19	-	28162770	MOLM13	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	-0.38010752501037137	[188]	[104]	-2	hSpCas9	negative selection	11589307
16853103	16853126	19	-	28162770	MOLM13	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-2.0104740531030942	[651]	[116]	-7	hSpCas9	negative selection	11589308
16854145	16854168	19	-	28162770	MOLM13	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-2.2618446433905515	[198]	[29]	-7	hSpCas9	negative selection	11589309
16829418	16829441	19	+	28162770	HEL	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	0.04435581551687917	[161]	[106]	0	hSpCas9	negative selection	11758666
16862958	16862981	19	+	28162770	HEL	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	0.4825618071096067	[294]	[263]	4	hSpCas9	negative selection	11758667
16829876	16829899	19	+	28162770	HEL	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	-2.5796535893360906	[167]	[17]	-8	hSpCas9	negative selection	11758668
16841767	16841790	19	+	28162770	HEL	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.1256971007649449	[447]	[262]	-1	hSpCas9	negative selection	11758669
16841821	16841844	19	+	28162770	HEL	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	-0.5621926192698685	[218]	[94]	-4	hSpCas9	negative selection	11758670
16846969	16846992	19	+	28162770	HEL	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-0.16234948308530228	[158]	[90]	-1	hSpCas9	negative selection	11758671
16847033	16847056	19	+	28162770	HEL	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.5640983827607923	[376]	[356]	5	hSpCas9	negative selection	11758672
16851499	16851522	19	-	28162770	HEL	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	-0.11214867016311159	[161]	[95]	-1	hSpCas9	negative selection	11758673
16853103	16853126	19	-	28162770	HEL	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-2.646767785194628	[527]	[53]	-8	hSpCas9	negative selection	11758674
16854145	16854168	19	-	28162770	HEL	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-2.7229106403163232	[133]	[12]	-8	hSpCas9	negative selection	11758675
16829418	16829441	19	+	28162770	MV411	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.8305649612184977	[189]	[89]	-5	hSpCas9	negative selection	11928032
16862958	16862981	19	+	28162770	MV411	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.28516954487724444	[229]	[158]	-2	hSpCas9	negative selection	11928033
16829876	16829899	19	+	28162770	MV411	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	-2.9331346948590458	[135]	[14]	-9	hSpCas9	negative selection	11928034
16841767	16841790	19	+	28162770	MV411	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.34967915022301005	[297]	[196]	-3	hSpCas9	negative selection	11928035
16841821	16841844	19	+	28162770	MV411	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	-1.3703148850560503	[177]	[57]	-7	hSpCas9	negative selection	11928036
16846969	16846992	19	+	28162770	MV411	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-1.833482444600792	[109]	[25]	-8	hSpCas9	negative selection	11928037
16847033	16847056	19	+	28162770	MV411	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.3565851652660281	[368]	[397]	3	hSpCas9	negative selection	11928038
16851499	16851522	19	-	28162770	MV411	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	-1.5203890070881916	[125]	[36]	-7	hSpCas9	negative selection	11928039
16853103	16853126	19	-	28162770	MV411	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-2.232031821091067	[289]	[51]	-8	hSpCas9	negative selection	11928040
16854145	16854168	19	-	28162770	MV411	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-2.4928031754162916	[146]	[21]	-8	hSpCas9	negative selection	11928041
16829418	16829441	19	+	28162770	MONOMAC1	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	0.44371343184734946	[92]	[144]	4	hSpCas9	negative selection	12097398
16862958	16862981	19	+	28162770	MONOMAC1	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.026104025079652704	[158]	[178]	0	hSpCas9	negative selection	12097399
16829876	16829899	19	+	28162770	MONOMAC1	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	-0.34641447109778034	[60]	[54]	-3	hSpCas9	negative selection	12097400
16841767	16841790	19	+	28162770	MONOMAC1	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	0.26355496065586126	[225]	[310]	2	hSpCas9	negative selection	12097401
16841821	16841844	19	+	28162770	MONOMAC1	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.10514731252939374	[102]	[126]	1	hSpCas9	negative selection	12097402
16846969	16846992	19	+	28162770	MONOMAC1	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-0.557626562316021	[103]	[80]	-5	hSpCas9	negative selection	12097403
16847033	16847056	19	+	28162770	MONOMAC1	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.5071873459090525	[204]	[333]	5	hSpCas9	negative selection	12097404
16851499	16851522	19	-	28162770	MONOMAC1	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	-0.2187319181588725	[66]	[65]	-2	hSpCas9	negative selection	12097405
16853103	16853126	19	-	28162770	MONOMAC1	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	1.0415740848350226	[277]	[655]	8	hSpCas9	negative selection	12097406
16854145	16854168	19	-	28162770	MONOMAC1	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	0.37000374566434013	[80]	[119]	3	hSpCas9	negative selection	12097407
16829418	16829441	19	+	28162770	OCIAML2	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.962835185043465	[31]	[90]	-6	hSpCas9	negative selection	12266764
16862958	16862981	19	+	28162770	OCIAML2	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.33598029854737926	[45]	[201]	-3	hSpCas9	negative selection	12266765
16829876	16829899	19	+	28162770	OCIAML2	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	-0.5848008451614722	[22]	[84]	-4	hSpCas9	negative selection	12266766
16841767	16841790	19	+	28162770	OCIAML2	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.44717085241817245	[60]	[247]	-4	hSpCas9	negative selection	12266767
16841821	16841844	19	+	28162770	OCIAML2	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	-0.3662931654274256	[29]	[128]	-3	hSpCas9	negative selection	12266768
16846969	16846992	19	+	28162770	OCIAML2	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	-0.9470678691851482	[15]	[45]	-6	hSpCas9	negative selection	12266769
16847033	16847056	19	+	28162770	OCIAML2	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	0.40588712132283844	[63]	[469]	4	hSpCas9	negative selection	12266770
16851499	16851522	19	-	28162770	OCIAML2	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	0.12474929142433339	[22]	[138]	1	hSpCas9	negative selection	12266771
16853103	16853126	19	-	28162770	OCIAML2	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	-1.7163862396441196	[82]	[139]	-8	hSpCas9	negative selection	12266772
16854145	16854168	19	-	28162770	OCIAML2	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-3.541019153133559	[20]	[9]	-9	hSpCas9	negative selection	12266773
16829418	16829441	19	+	28162770	OCIAML3	viability	GACATGGCGCACGCTGGCGGTGG	SIN3B	ENSG00000127511	-0.29632709168347804	[47]	[117]	-2	hSpCas9	negative selection	12436130
16862958	16862981	19	+	28162770	OCIAML3	viability	GATTCCAGGATATAGTGCAGGGG	SIN3B	ENSG00000127511	-0.09281349729560487	[64]	[183]	0	hSpCas9	negative selection	12436131
16829876	16829899	19	+	28162770	OCIAML3	viability	TGAAGGAGTTCAAAAGCCAGAGG	SIN3B	ENSG00000127511	0.0042516830104509795	[35]	[108]	0	hSpCas9	negative selection	12436132
16841767	16841790	19	+	28162770	OCIAML3	viability	GGAGAATTCGCACAACCACGGGG	SIN3B	ENSG00000127511	-0.4923122432548122	[88]	[190]	-4	hSpCas9	negative selection	12436133
16841821	16841844	19	+	28162770	OCIAML3	viability	GTATAAAGAGGACAAACCCCAGG	SIN3B	ENSG00000127511	0.39281697092810364	[54]	[217]	3	hSpCas9	negative selection	12436134
16846969	16846992	19	+	28162770	OCIAML3	viability	GAAGGAGCAGCTGAACACGAGGG	SIN3B	ENSG00000127511	0.5325247656047687	[29]	[130]	5	hSpCas9	negative selection	12436135
16847033	16847056	19	+	28162770	OCIAML3	viability	GAGGTGGCCAACCTCTTCCGGGG	SIN3B	ENSG00000127511	-0.5001407168599411	[118]	[253]	-4	hSpCas9	negative selection	12436136
16851499	16851522	19	-	28162770	OCIAML3	viability	GACACGGGGCGGAGGAGCGAGGG	SIN3B	ENSG00000127511	0.059434598279759485	[47]	[150]	0	hSpCas9	negative selection	12436137
16853103	16853126	19	-	28162770	OCIAML3	viability	GTACTTCCCCACTGCAGCGATGG	SIN3B	ENSG00000127511	0.17933034350700483	[140]	[481]	1	hSpCas9	negative selection	12436138
16854145	16854168	19	-	28162770	OCIAML3	viability	CCTGGCTCTTCAGCACCCGGCGG	SIN3B	ENSG00000127511	-0.3845542746952133	[31]	[73]	-3	hSpCas9	negative selection	12436139