Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6495
• Symbol:SIX1
• Description:SIX homeobox 1

DataSource: http://genomecrispr.dkfz.de/#!/results/SIX1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
60649027	60649050	14	-	26472758	Jiyoye	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	1.031666246413667	[143]	[221]	6	hSpCas9	negative selection	147121
60648782	60648805	14	-	26472758	Jiyoye	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	-1.3735115900896508	[133]	[38]	-7	hSpCas9	negative selection	147122
60649008	60649031	14	-	26472758	Jiyoye	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.3713746600780266	[101]	[198]	7	hSpCas9	negative selection	147123
60648931	60648954	14	+	26472758	Jiyoye	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	1.2467107093126273	[151]	[271]	7	hSpCas9	negative selection	147124
60648907	60648930	14	-	26472758	Jiyoye	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.4189046740879805	[244]	[246]	3	hSpCas9	negative selection	147125
60648854	60648877	14	+	26472758	Jiyoye	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.24354212593128466	[428]	[382]	1	hSpCas9	negative selection	147126
60648754	60648777	14	+	26472758	Jiyoye	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.6668251999379035	[119]	[56]	-5	hSpCas9	negative selection	147127
60648643	60648666	14	-	26472758	Jiyoye	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	0.023846741954367756	[59]	[45]	0	hSpCas9	negative selection	147128
60649156	60649179	14	-	26472758	Jiyoye	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	-0.7448277119391766	[379]	[170]	-5	hSpCas9	negative selection	147129
60649116	60649139	14	-	26472758	Jiyoye	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	-1.1163865745511394	[91]	[31]	-6	hSpCas9	negative selection	147130
60649027	60649050	14	-	26472758	KBM7	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.4044919407847557	[938,841]	[698,423]	4	hSpCas9	negative selection	338239
60648782	60648805	14	-	26472758	KBM7	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	-0.33579223378948275	[192,258]	[78,91]	-3	hSpCas9	negative selection	338240
60649008	60649031	14	-	26472758	KBM7	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.8928119928223581	[678,379]	[513,394]	8	hSpCas9	negative selection	338241
60648931	60648954	14	+	26472758	KBM7	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	0.33466595959669987	[1240,683]	[601,515]	3	hSpCas9	negative selection	338242
60648907	60648930	14	-	26472758	KBM7	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.35635398148182906	[1455,1039]	[910,590]	4	hSpCas9	negative selection	338243
60648854	60648877	14	+	26472758	KBM7	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.3393407262338981	[1741,1050]	[959,682]	3	hSpCas9	negative selection	338244
60648754	60648777	14	+	26472758	KBM7	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.4495810516304922	[850,791]	[506,546]	5	hSpCas9	negative selection	338245
60648643	60648666	14	-	26472758	KBM7	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	1.010124486496602	[260,153]	[120,255]	9	hSpCas9	negative selection	338246
60649156	60649179	14	-	26472758	KBM7	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	0.13099880098051164	[1125,1049]	[656,474]	1	hSpCas9	negative selection	338247
60649116	60649139	14	-	26472758	KBM7	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.8755391544787338	[199,217]	[125,231]	8	hSpCas9	negative selection	338248
60649027	60649050	14	-	26472758	Raji	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.7047510569855363	[385]	[145]	6	hSpCas9	negative selection	529357
60648782	60648805	14	-	26472758	Raji	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	0.18984569556557251	[101]	[26]	1	hSpCas9	negative selection	529358
60649008	60649031	14	-	26472758	Raji	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.5559735943634699	[254]	[86]	5	hSpCas9	negative selection	529359
60648931	60648954	14	+	26472758	Raji	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	-0.027666424790253163	[469]	[106]	0	hSpCas9	negative selection	529360
60648907	60648930	14	-	26472758	Raji	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.5308771915076057	[578]	[92]	-4	hSpCas9	negative selection	529361
60648854	60648877	14	+	26472758	Raji	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.5086903187903349	[738]	[243]	5	hSpCas9	negative selection	529362
60648754	60648777	14	+	26472758	Raji	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.1267488602405304	[295]	[74]	1	hSpCas9	negative selection	529363
60648643	60648666	14	-	26472758	Raji	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	0.877901689250832	[67]	[28]	7	hSpCas9	negative selection	529364
60649156	60649179	14	-	26472758	Raji	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	0.41116428355070234	[511]	[157]	4	hSpCas9	negative selection	529365
60649116	60649139	14	-	26472758	Raji	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.7498315307555158	[122]	[47]	7	hSpCas9	negative selection	529366
60649027	60649050	14	-	26472758	K562	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.26819401546954624	[661]	[672]	2	hSpCas9	negative selection	720475
60648782	60648805	14	-	26472758	K562	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	-0.26810176038607003	[300]	[210]	-2	hSpCas9	negative selection	720476
60649008	60649031	14	-	26472758	K562	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.5339253448614318	[431]	[1055]	9	hSpCas9	negative selection	720477
60648931	60648954	14	+	26472758	K562	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	0.5303714693338345	[738]	[900]	4	hSpCas9	negative selection	720478
60648907	60648930	14	-	26472758	K562	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.47888398130346976	[917]	[1079]	4	hSpCas9	negative selection	720479
60648854	60648877	14	+	26472758	K562	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	-0.3834959182392561	[1124]	[727]	-3	hSpCas9	negative selection	720480
60648754	60648777	14	+	26472758	K562	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.39512443339736436	[444]	[493]	3	hSpCas9	negative selection	720481
60648643	60648666	14	-	26472758	K562	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	0.3336860657635342	[187]	[199]	2	hSpCas9	negative selection	720482
60649156	60649179	14	-	26472758	K562	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	-0.0697737184413103	[929]	[747]	0	hSpCas9	negative selection	720483
60649116	60649139	14	-	26472758	K562	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	1.128094609699215	[141]	[261]	8	hSpCas9	negative selection	720484
60646399	60646422	14	+	26627737	DLD1	viability	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-0.6613658838270213	[470]	[125,65,86]	-6	hSpCas9	negative selection	788942
60646423	60646446	14	+	26627737	DLD1	viability	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.5522031245616912	[706]	[350,400,236]	5	hSpCas9	negative selection	788943
60646512	60646535	14	-	26627737	DLD1	viability	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	0.08040254246380651	[602]	[222,262,125]	0	hSpCas9	negative selection	788944
60648723	60648746	14	+	26627737	DLD1	viability	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	-0.681373395076962	[740]	[202,166,74]	-6	hSpCas9	negative selection	788945
60649045	60649068	14	+	26627737	DLD1	viability	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.28966545742362837	[967]	[392,423,304]	3	hSpCas9	negative selection	788946
60649169	60649192	14	+	26627737	DLD1	viability	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	0.39984557105474783	[689]	[270,383,213]	4	hSpCas9	negative selection	788947
60646399	60646422	14	+	26627737	GBM cells	viability after 5 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-0.326440960306624	[324]	[131,145]	-5	hSpCas9	negative selection	871257
60646423	60646446	14	+	26627737	GBM cells	viability after 5 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	-0.5223826148648407	[307]	[119,109]	-7	hSpCas9	negative selection	871258
60646512	60646535	14	-	26627737	GBM cells	viability after 5 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.3584181715839249	[403]	[169,167]	-5	hSpCas9	negative selection	871259
60648723	60648746	14	+	26627737	GBM cells	viability after 5 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	-0.10108612511431442	[209]	[110,98]	-1	hSpCas9	negative selection	871260
60649045	60649068	14	+	26627737	GBM cells	viability after 5 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.5251526511853608	[378]	[304,279]	7	hSpCas9	negative selection	871261
60649169	60649192	14	+	26627737	GBM cells	viability after 5 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.5097597188782966	[376]	[153,129]	-7	hSpCas9	negative selection	871262
60646399	60646422	14	+	26627737	GBM cells	viability after 13 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-0.37722811694222635	[324]	[148,124]	-4	hSpCas9	negative selection	953572
60646423	60646446	14	+	26627737	GBM cells	viability after 13 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.06967636305737684	[307]	[181,169]	0	hSpCas9	negative selection	953573
60646512	60646535	14	-	26627737	GBM cells	viability after 13 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.7682566008631283	[403]	[72,173]	-7	hSpCas9	negative selection	953574
60648723	60648746	14	+	26627737	GBM cells	viability after 13 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	-0.2982401410231516	[209]	[106,80]	-4	hSpCas9	negative selection	953575
60649045	60649068	14	+	26627737	GBM cells	viability after 13 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.7064393550709589	[378]	[409,274]	8	hSpCas9	negative selection	953576
60649169	60649192	14	+	26627737	GBM cells	viability after 13 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.7344932039723111	[376]	[144,104]	-7	hSpCas9	negative selection	953577
60646399	60646422	14	+	26627737	GBM cells	viability after 21 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-0.5666877095891395	[324]	[125,112]	-5	hSpCas9	negative selection	1035887
60646423	60646446	14	+	26627737	GBM cells	viability after 21 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.886102461117684	[307]	[314,303]	8	hSpCas9	negative selection	1035888
60646512	60646535	14	-	26627737	GBM cells	viability after 21 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.9007792724644229	[403]	[127,107]	-7	hSpCas9	negative selection	1035889
60648723	60648746	14	+	26627737	GBM cells	viability after 21 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	-0.6518937936973435	[209]	[69,74]	-5	hSpCas9	negative selection	1035890
60649045	60649068	14	+	26627737	GBM cells	viability after 21 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.6318933473745469	[378]	[340,298]	6	hSpCas9	negative selection	1035891
60649169	60649192	14	+	26627737	GBM cells	viability after 21 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-1.8642637410728695	[376]	[61,50]	-8	hSpCas9	negative selection	1035892
60646399	60646422	14	+	26627737	RPE1	viability after 9 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-0.9270487579564672	[884]	[98,205]	-6	hSpCas9	negative selection	1118202
60646423	60646446	14	+	26627737	RPE1	viability after 9 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.9622378102009254	[985]	[500,730]	6	hSpCas9	negative selection	1118203
60646512	60646535	14	-	26627737	RPE1	viability after 9 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.2175635301420666	[970]	[229,301]	-1	hSpCas9	negative selection	1118204
60648723	60648746	14	+	26627737	RPE1	viability after 9 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.22802570969573369	[822]	[251,365]	1	hSpCas9	negative selection	1118205
60649045	60649068	14	+	26627737	RPE1	viability after 9 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	1.1423374060476341	[1174]	[687,971]	7	hSpCas9	negative selection	1118206
60649169	60649192	14	+	26627737	RPE1	viability after 9 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	0.3528858579070144	[497]	[130,286]	2	hSpCas9	negative selection	1118207
60646399	60646422	14	+	26627737	RPE1	viability after 12 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-1.4595089780254513	[884]	[67,105]	-7	hSpCas9	negative selection	1200517
60646423	60646446	14	+	26627737	RPE1	viability after 12 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.7248898687741395	[985]	[414,461]	4	hSpCas9	negative selection	1200518
60646512	60646535	14	-	26627737	RPE1	viability after 12 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-1.3710466225324782	[970]	[78,123]	-7	hSpCas9	negative selection	1200519
60648723	60648746	14	+	26627737	RPE1	viability after 12 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	-0.5178413230714418	[822]	[168,138]	-4	hSpCas9	negative selection	1200520
60649045	60649068	14	+	26627737	RPE1	viability after 12 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.783916353021465	[1174]	[374,721]	5	hSpCas9	negative selection	1200521
60649169	60649192	14	+	26627737	RPE1	viability after 12 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	0.6061080841820125	[497]	[191,215]	4	hSpCas9	negative selection	1200522
60646399	60646422	14	+	26627737	RPE1	viability after 15 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-1.7041384920494962	[884]	[29,121]	-8	hSpCas9	negative selection	1282832
60646423	60646446	14	+	26627737	RPE1	viability after 15 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.9065726977520744	[985]	[530,514]	5	hSpCas9	negative selection	1282833
60646512	60646535	14	-	26627737	RPE1	viability after 15 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-1.5914902240920132	[970]	[82,98]	-7	hSpCas9	negative selection	1282834
60648723	60648746	14	+	26627737	RPE1	viability after 15 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.4714808432323534	[822]	[502,148]	3	hSpCas9	negative selection	1282835
60649045	60649068	14	+	26627737	RPE1	viability after 15 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	1.6218464018998981	[1174]	[1277,776]	8	hSpCas9	negative selection	1282836
60649169	60649192	14	+	26627737	RPE1	viability after 15 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	0.4144768852027708	[497]	[116,255]	2	hSpCas9	negative selection	1282837
60646399	60646422	14	+	26627737	RPE1	viability after 18 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-2.2147595681579486	[884]	[49,52]	-8	hSpCas9	negative selection	1365147
60646423	60646446	14	+	26627737	RPE1	viability after 18 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.62517132054018	[985]	[203,630]	4	hSpCas9	negative selection	1365148
60646512	60646535	14	-	26627737	RPE1	viability after 18 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-1.114005098738574	[970]	[122,118]	-6	hSpCas9	negative selection	1365149
60648723	60648746	14	+	26627737	RPE1	viability after 18 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.05672787829845233	[822]	[274,183]	0	hSpCas9	negative selection	1365150
60649045	60649068	14	+	26627737	RPE1	viability after 18 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.9032844560471598	[1174]	[463,730]	5	hSpCas9	negative selection	1365151
60649169	60649192	14	+	26627737	RPE1	viability after 18 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	0.31864257403200846	[497]	[97,241]	2	hSpCas9	negative selection	1365152
60646399	60646422	14	+	26627737	HeLa	viability after 8 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	0.4867836617887383	[314]	[270,180,144]	4	hSpCas9	negative selection	1447462
60646423	60646446	14	+	26627737	HeLa	viability after 8 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.3402680680198618	[376]	[451,93,135]	3	hSpCas9	negative selection	1447463
60646512	60646535	14	-	26627737	HeLa	viability after 8 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.9324459488385346	[832]	[203,180,187]	-7	hSpCas9	negative selection	1447464
60648723	60648746	14	+	26627737	HeLa	viability after 8 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.07966918018145575	[429]	[87,341,142]	0	hSpCas9	negative selection	1447465
60649045	60649068	14	+	26627737	HeLa	viability after 8 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.9724482811372549	[388]	[355,466,188]	7	hSpCas9	negative selection	1447466
60649169	60649192	14	+	26627737	HeLa	viability after 8 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.7193232582679155	[887]	[225,164,305]	-6	hSpCas9	negative selection	1447467
60646399	60646422	14	+	26627737	HeLa	viability after 12 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	1.092937706102484	[314]	[454,137,259]	7	hSpCas9	negative selection	1529777
60646423	60646446	14	+	26627737	HeLa	viability after 12 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	-0.2290646652498074	[376]	[18,193,175]	-2	hSpCas9	negative selection	1529778
60646512	60646535	14	-	26627737	HeLa	viability after 12 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.817116803031449	[832]	[65,151,368]	-6	hSpCas9	negative selection	1529779
60648723	60648746	14	+	26627737	HeLa	viability after 12 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	-0.6985525264752581	[429]	[159,61,112]	-6	hSpCas9	negative selection	1529780
60649045	60649068	14	+	26627737	HeLa	viability after 12 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	1.313781041890502	[388]	[143,507,527]	8	hSpCas9	negative selection	1529781
60649169	60649192	14	+	26627737	HeLa	viability after 12 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.7619794598003112	[887]	[191,239,213]	-6	hSpCas9	negative selection	1529782
60646399	60646422	14	+	26627737	HeLa	viability after 15 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	0.7654379995589486	[314]	[246,231,170]	6	hSpCas9	negative selection	1612092
60646423	60646446	14	+	26627737	HeLa	viability after 15 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.3108414565823602	[376]	[174,209,185]	2	hSpCas9	negative selection	1612093
60646512	60646535	14	-	26627737	HeLa	viability after 15 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.37966621487747676	[832]	[139,388,253]	-3	hSpCas9	negative selection	1612094
60648723	60648746	14	+	26627737	HeLa	viability after 15 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	-0.4586666001424227	[429]	[93,155,132]	-4	hSpCas9	negative selection	1612095
60649045	60649068	14	+	26627737	HeLa	viability after 15 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	1.5810860174978822	[388]	[393,656,362]	9	hSpCas9	negative selection	1612096
60649169	60649192	14	+	26627737	HeLa	viability after 15 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.7657231658648365	[887]	[239,166,231]	-6	hSpCas9	negative selection	1612097
60646399	60646422	14	+	26627737	HeLa	viability after 18 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	0.7896943115082101	[314]	[164,201,170]	6	hSpCas9	negative selection	1694407
60646423	60646446	14	+	26627737	HeLa	viability after 18 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.3072229955236332	[376]	[121,166,185]	2	hSpCas9	negative selection	1694408
60646512	60646535	14	-	26627737	HeLa	viability after 18 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.366119911116628	[832]	[93,327,253]	-3	hSpCas9	negative selection	1694409
60648723	60648746	14	+	26627737	HeLa	viability after 18 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	-0.4471174343402941	[429]	[65,127,132]	-4	hSpCas9	negative selection	1694410
60649045	60649068	14	+	26627737	HeLa	viability after 18 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	1.5669736851389708	[388]	[256,541,362]	8	hSpCas9	negative selection	1694411
60649169	60649192	14	+	26627737	HeLa	viability after 18 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.7423896660712063	[887]	[167,137,231]	-6	hSpCas9	negative selection	1694412
60646399	60646422	14	+	26627737	HCT116	viability after 6 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-0.5609415788757012	[603]	[142,20]	-3	hSpCas9	negative selection	1776722
60646423	60646446	14	+	26627737	HCT116	viability after 6 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.6528348149303729	[987]	[220,256]	3	hSpCas9	negative selection	1776723
60646512	60646535	14	-	26627737	HCT116	viability after 6 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	0.47601058680705244	[912]	[120,242]	2	hSpCas9	negative selection	1776724
60648723	60648746	14	+	26627737	HCT116	viability after 6 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	-0.1761506865348663	[577]	[218,3]	-1	hSpCas9	negative selection	1776725
60649045	60649068	14	+	26627737	HCT116	viability after 6 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.43832581465728687	[797]	[91,212]	2	hSpCas9	negative selection	1776726
60649169	60649192	14	+	26627737	HCT116	viability after 6 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	0.5432268099910176	[500]	[146,96]	3	hSpCas9	negative selection	1776727
60646399	60646422	14	+	26627737	HCT116	viability after 8 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	0.6351688107000575	[241]	[225,216,178]	6	hSpCas9	negative selection	1859037
60646423	60646446	14	+	26627737	HCT116	viability after 8 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.4873780527293369	[275]	[211,247,179]	5	hSpCas9	negative selection	1859038
60646512	60646535	14	-	26627737	HCT116	viability after 8 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-1.0122576507394023	[438]	[179,72,107]	-8	hSpCas9	negative selection	1859039
60648723	60648746	14	+	26627737	HCT116	viability after 8 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	-0.01623056385919286	[246]	[206,142,55]	0	hSpCas9	negative selection	1859040
60649045	60649068	14	+	26627737	HCT116	viability after 8 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	-0.25013313878160653	[492]	[247,242,194]	-3	hSpCas9	negative selection	1859041
60649169	60649192	14	+	26627737	HCT116	viability after 8 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.7704761457688936	[587]	[122,121,321]	-7	hSpCas9	negative selection	1859042
60646399	60646422	14	+	26627737	HCT116	viability after 9 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	1.0106010119551319	[603]	[253,380]	7	hSpCas9	negative selection	1941352
60646423	60646446	14	+	26627737	HCT116	viability after 9 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.4884957444204576	[987]	[449,306]	3	hSpCas9	negative selection	1941353
60646512	60646535	14	-	26627737	HCT116	viability after 9 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.048160549618952664	[912]	[337,154]	0	hSpCas9	negative selection	1941354
60648723	60648746	14	+	26627737	HCT116	viability after 9 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.5849044400199983	[577]	[221,238]	4	hSpCas9	negative selection	1941355
60649045	60649068	14	+	26627737	HCT116	viability after 9 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	-0.11577866284634064	[797]	[261,144]	-1	hSpCas9	negative selection	1941356
60649169	60649192	14	+	26627737	HCT116	viability after 9 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	0.1534838549843314	[500]	[145,150]	1	hSpCas9	negative selection	1941357
60646399	60646422	14	+	26627737	HCT116	viability after 12 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	0.9356863030116553	[241]	[181,235,316]	7	hSpCas9	negative selection	2023667
60646423	60646446	14	+	26627737	HCT116	viability after 12 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.38391278198976014	[275]	[187,192,186]	4	hSpCas9	negative selection	2023668
60646512	60646535	14	-	26627737	HCT116	viability after 12 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.2536994064022702	[438]	[296,134,137]	-3	hSpCas9	negative selection	2023669
60648723	60648746	14	+	26627737	HCT116	viability after 12 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.19163448411023956	[246]	[193,159,86]	2	hSpCas9	negative selection	2023670
60649045	60649068	14	+	26627737	HCT116	viability after 12 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	-0.05266508514313217	[492]	[175,254,324]	0	hSpCas9	negative selection	2023671
60649169	60649192	14	+	26627737	HCT116	viability after 12 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.6548944627226139	[587]	[81,368,151]	-6	hSpCas9	negative selection	2023672
60646399	60646422	14	+	26627737	HCT116	viability after 15 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	1.0128714526771432	[241]	[306,208,327]	8	hSpCas9	negative selection	2105982
60646423	60646446	14	+	26627737	HCT116	viability after 15 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.3463774555449744	[275]	[237,169,200]	3	hSpCas9	negative selection	2105983
60646512	60646535	14	-	26627737	HCT116	viability after 15 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.2523540254809317	[438]	[200,164,266]	-3	hSpCas9	negative selection	2105984
60648723	60648746	14	+	26627737	HCT116	viability after 15 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.49057491453756985	[246]	[309,153,147]	4	hSpCas9	negative selection	2105985
60649045	60649068	14	+	26627737	HCT116	viability after 15 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.19764695616480188	[492]	[342,198,432]	2	hSpCas9	negative selection	2105986
60649169	60649192	14	+	26627737	HCT116	viability after 15 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-1.1176909837125102	[587]	[199,178,93]	-8	hSpCas9	negative selection	2105987
60646399	60646422	14	+	26627737	HCT116	viability after 18 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	0.46495424280927267	[241]	[163,112,212]	4	hSpCas9	negative selection	2188297
60646423	60646446	14	+	26627737	HCT116	viability after 18 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	0.34475888337331934	[275]	[210,163,131]	3	hSpCas9	negative selection	2188298
60646512	60646535	14	-	26627737	HCT116	viability after 18 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.6274704259486372	[438]	[192,72,150]	-5	hSpCas9	negative selection	2188299
60648723	60648746	14	+	26627737	HCT116	viability after 18 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.5338263010471407	[246]	[80,335,86]	4	hSpCas9	negative selection	2188300
60649045	60649068	14	+	26627737	HCT116	viability after 18 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	-0.11170637614645273	[492]	[230,119,321]	-1	hSpCas9	negative selection	2188301
60649169	60649192	14	+	26627737	HCT116	viability after 18 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-1.2195674287866125	[587]	[156,177,22]	-8	hSpCas9	negative selection	2188302
60649052	60649075	14	+	24336569	HL60	viability	GTTCTTGTGCAGGTGGTCGCAGG	SIX1	ENSG00000126778	0.4773925087527946	[947]	[2792]	4	hSpCas9	negative selection	2295203
60649069	60649092	14	+	24336569	HL60	viability	CGCAGGCGGGCAGTGACCACAGG	SIX1	ENSG00000126778	0.004333772126332958	[611]	[1298]	0	hSpCas9	negative selection	2295204
60649081	60649104	14	+	24336569	HL60	viability	GTGACCACAGGAACCTGCCCAGG	SIX1	ENSG00000126778	-0.15118772288321647	[974]	[1857]	-1	hSpCas9	negative selection	2295205
60649090	60649113	14	+	24336569	HL60	viability	GGAACCTGCCCAGGCGCTCCAGG	SIX1	ENSG00000126778	0.06776190814558003	[155]	[345]	0	hSpCas9	negative selection	2295206
60649098	60649121	14	-	24336569	HL60	viability	GGCGGAAACCTGGAGCGCCTGGG	SIX1	ENSG00000126778	4.452514471373455	[2]	[138]	9	hSpCas9	negative selection	2295207
60649108	60649131	14	-	24336569	HL60	viability	TCTGCAGCAAGGCGGAAACCTGG	SIX1	ENSG00000126778	-0.2676263104644515	[792]	[1393]	-2	hSpCas9	negative selection	2295208
60649116	60649139	14	-	24336569	HL60	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	-0.5896110042992215	[671]	[944]	-5	hSpCas9	negative selection	2295209
60649147	60649170	14	-	24336569	HL60	viability	TGGCTTTACGCAGGAGCAAGTGG	SIX1	ENSG00000126778	-0.7528777027068487	[734]	[922]	-6	hSpCas9	negative selection	2295210
60649155	60649178	14	+	24336569	HL60	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.908479299437526	[627]	[707]	-7	hSpCas9	negative selection	2295211
60649167	60649190	14	-	24336569	HL60	viability	ATGTCGATGCTGCCGTCGTTTGG	SIX1	ENSG00000126778	0.7241794392103628	[481]	[1684]	6	hSpCas9	negative selection	2295212
60649052	60649075	14	+	24336569	KBM7	viability	GTTCTTGTGCAGGTGGTCGCAGG	SIX1	ENSG00000126778	0.5971465844678255	[658]	[2718]	5	hSpCas9	negative selection	2362380
60649069	60649092	14	+	24336569	KBM7	viability	CGCAGGCGGGCAGTGACCACAGG	SIX1	ENSG00000126778	0.92089148427551	[365]	[1889]	7	hSpCas9	negative selection	2362381
60649081	60649104	14	+	24336569	KBM7	viability	GTGACCACAGGAACCTGCCCAGG	SIX1	ENSG00000126778	-0.46390560662980374	[1332]	[2635]	-4	hSpCas9	negative selection	2362382
60649090	60649113	14	+	24336569	KBM7	viability	GGAACCTGCCCAGGCGCTCCAGG	SIX1	ENSG00000126778	-0.34481962212368167	[148]	[319]	-3	hSpCas9	negative selection	2362383
60649098	60649121	14	-	24336569	KBM7	viability	GGCGGAAACCTGGAGCGCCTGGG	SIX1	ENSG00000126778	0.49909130104499067	[61]	[238]	4	hSpCas9	negative selection	2362384
60649108	60649131	14	-	24336569	KBM7	viability	TCTGCAGCAAGGCGGAAACCTGG	SIX1	ENSG00000126778	0.22424876740689637	[520]	[1659]	2	hSpCas9	negative selection	2362385
60649116	60649139	14	-	24336569	KBM7	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	-0.05935452840400521	[352]	[923]	0	hSpCas9	negative selection	2362386
60649147	60649170	14	-	24336569	KBM7	viability	TGGCTTTACGCAGGAGCAAGTGG	SIX1	ENSG00000126778	0.057829127836649966	[378]	[1075]	0	hSpCas9	negative selection	2362387
60649155	60649178	14	+	24336569	KBM7	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.47103816937287135	[526]	[1036]	-4	hSpCas9	negative selection	2362388
60649167	60649190	14	-	24336569	KBM7	viability	ATGTCGATGCTGCCGTCGTTTGG	SIX1	ENSG00000126778	-0.13038902066818345	[365]	[911]	-1	hSpCas9	negative selection	2362389
60649514	60649537	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCGTCCCCGGCACGCTGATTGG	SIX1	ENSG00000126778	0.9489388901607139	[66,98]	[37,31]	4	dCas9-VP64	positive selection	2438957
60649597	60649620	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCCCCGCTCTGGGCGGTGCGG	SIX1	ENSG00000126778	-2.02620399904817	[67,444]	[10,15]	-9	dCas9-VP64	positive selection	2438958
60649535	60649558	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTGCCGGCGGCGCCTATCCGG	SIX1	ENSG00000126778	0.8306599899248606	[44,240]	[2,113]	3	dCas9-VP64	positive selection	2438959
60649514	60649537	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCGTCCCCGGCACGCTGATTGG	SIX1	ENSG00000126778	0.5813804918374188	[82,66]	[43,28]	4	dCas9-VP64	positive selection	2534212
60649597	60649620	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCCCCGCTCTGGGCGGTGCGG	SIX1	ENSG00000126778	-1.0331783549169848	[51,184]	[22,12]	-8	dCas9-VP64	positive selection	2534213
60649535	60649558	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTGCCGGCGGCGCCTATCCGG	SIX1	ENSG00000126778	-0.838213982841957	[336,77]	[63,13]	-7	dCas9-VP64	positive selection	2534214
60649024	60649047	14	-	27260157	DLD1	viability	CGTACTCAAGGCCAAGGCGGTGG	SIX1	ENSG00000126778	-0.144439912014829	[]	[]	-1	hSpCas9	negative selection	2576428
60649116	60649139	14	-	27260157	DLD1	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	-0.253747028425868	[]	[]	-2	hSpCas9	negative selection	2578114
60649069	60649092	14	+	27260157	DLD1	viability	CGCAGGCGGGCAGTGACCACAGG	SIX1	ENSG00000126778	-1.18472648893026	[]	[]	-7	hSpCas9	negative selection	2580098
60649169	60649192	14	+	27260157	DLD1	viability	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	0.627142982986013	[]	[]	8	hSpCas9	negative selection	2581000
60649108	60649131	14	-	27260157	DLD1	viability	TCTGCAGCAAGGCGGAAACCTGG	SIX1	ENSG00000126778	-0.171912823176887	[]	[]	-1	hSpCas9	negative selection	2582518
60648949	60648972	14	+	27260157	DLD1	viability	GGTGGTTGTGAGGCGAGAACTGG	SIX1	ENSG00000126778	-0.115810031521237	[]	[]	-1	hSpCas9	negative selection	2583790
60649098	60649121	14	-	27260157	DLD1	viability	GGCGGAAACCTGGAGCGCCTGGG	SIX1	ENSG00000126778	0.648026727771987	[]	[]	8	hSpCas9	negative selection	2585607
60649042	60649065	14	+	27260157	DLD1	viability	GTACGCTCTCGTTCTTGTGCAGG	SIX1	ENSG00000126778	-0.39615223899504	[]	[]	-3	hSpCas9	negative selection	2586980
60649085	60649108	14	-	27260157	DLD1	viability	AGCGCCTGGGCAGGTTCCTGTGG	SIX1	ENSG00000126778	-0.129868628865114	[]	[]	-1	hSpCas9	negative selection	2604693
60648926	60648949	14	+	27260157	DLD1	viability	CAGCCACAGTTGCTGCAGTTTGG	SIX1	ENSG00000126778	0.514947483089972	[]	[]	8	hSpCas9	negative selection	2604957
60648922	60648945	14	-	27260157	DLD1	viability	ACTGCAGCAACTGTGGCTGAAGG	SIX1	ENSG00000126778	1.34488252608551	[]	[]	9	hSpCas9	negative selection	2606239
60649147	60649170	14	-	27260157	DLD1	viability	TGGCTTTACGCAGGAGCAAGTGG	SIX1	ENSG00000126778	-1.20981438162473	[]	[]	-7	hSpCas9	negative selection	2608196
60649081	60649104	14	+	27260157	DLD1	viability	GTGACCACAGGAACCTGCCCAGG	SIX1	ENSG00000126778	1.47173180494001	[]	[]	9	hSpCas9	negative selection	2613720
60649008	60649031	14	-	27260157	DLD1	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.146084498278638	[]	[]	3	hSpCas9	negative selection	2619042
60649167	60649190	14	-	27260157	DLD1	viability	ATGTCGATGCTGCCGTCGTTTGG	SIX1	ENSG00000126778	0.328256729610479	[]	[]	4	hSpCas9	negative selection	2622867
60649155	60649178	14	+	27260157	DLD1	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.128950573194569	[]	[]	3	hSpCas9	negative selection	2642103
60649090	60649113	14	+	27260157	DLD1	viability	GGAACCTGCCCAGGCGCTCCAGG	SIX1	ENSG00000126778	0.213362809722137	[]	[]	3	hSpCas9	negative selection	2644494
60649052	60649075	14	+	27260157	DLD1	viability	GTTCTTGTGCAGGTGGTCGCAGG	SIX1	ENSG00000126778	-1.09576522307317	[]	[]	-7	hSpCas9	negative selection	2645756
60649013	60649036	14	+	27260157	DLD1	viability	GTGGAAGGCGACCACCGCCTTGG	SIX1	ENSG00000126778	0.610492437473065	[]	[]	8	hSpCas9	negative selection	2646824
60649036	60649059	14	-	27260157	DLD1	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	0.254899537785192	[]	[]	4	hSpCas9	negative selection	2648075
60649024	60649047	14	-	27260157	HT1080	viability	CGTACTCAAGGCCAAGGCGGTGG	SIX1	ENSG00000126778	-0.475498795061187	[]	[]	-7	hSpCas9	negative selection	2652558
60649116	60649139	14	-	27260157	HT1080	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.633170020551917	[]	[]	5	hSpCas9	negative selection	2654244
60649069	60649092	14	+	27260157	HT1080	viability	CGCAGGCGGGCAGTGACCACAGG	SIX1	ENSG00000126778	-0.659563495400294	[]	[]	-8	hSpCas9	negative selection	2656228
60649169	60649192	14	+	27260157	HT1080	viability	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	0.479815735222775	[]	[]	4	hSpCas9	negative selection	2657130
60649108	60649131	14	-	27260157	HT1080	viability	TCTGCAGCAAGGCGGAAACCTGG	SIX1	ENSG00000126778	-0.872385548393863	[]	[]	-8	hSpCas9	negative selection	2658648
60648949	60648972	14	+	27260157	HT1080	viability	GGTGGTTGTGAGGCGAGAACTGG	SIX1	ENSG00000126778	-1.92821226214628	[]	[]	-9	hSpCas9	negative selection	2659920
60649098	60649121	14	-	27260157	HT1080	viability	GGCGGAAACCTGGAGCGCCTGGG	SIX1	ENSG00000126778	-0.124710543394809	[]	[]	0	hSpCas9	negative selection	2661737
60649042	60649065	14	+	27260157	HT1080	viability	GTACGCTCTCGTTCTTGTGCAGG	SIX1	ENSG00000126778	-1.04595698531713	[]	[]	-8	hSpCas9	negative selection	2663110
60649085	60649108	14	-	27260157	HT1080	viability	AGCGCCTGGGCAGGTTCCTGTGG	SIX1	ENSG00000126778	-0.379921390266538	[]	[]	-7	hSpCas9	negative selection	2680823
60648926	60648949	14	+	27260157	HT1080	viability	CAGCCACAGTTGCTGCAGTTTGG	SIX1	ENSG00000126778	0.0652317670084853	[]	[]	0	hSpCas9	negative selection	2681087
60648922	60648945	14	-	27260157	HT1080	viability	ACTGCAGCAACTGTGGCTGAAGG	SIX1	ENSG00000126778	0.809481350041354	[]	[]	7	hSpCas9	negative selection	2682369
60649147	60649170	14	-	27260157	HT1080	viability	TGGCTTTACGCAGGAGCAAGTGG	SIX1	ENSG00000126778	-0.0370907773263429	[]	[]	0	hSpCas9	negative selection	2684326
60649081	60649104	14	+	27260157	HT1080	viability	GTGACCACAGGAACCTGCCCAGG	SIX1	ENSG00000126778	-0.13374545299825	[]	[]	0	hSpCas9	negative selection	2689850
60649008	60649031	14	-	27260157	HT1080	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.30682205099899	[]	[]	9	hSpCas9	negative selection	2695172
60649167	60649190	14	-	27260157	HT1080	viability	ATGTCGATGCTGCCGTCGTTTGG	SIX1	ENSG00000126778	-0.18153246161465	[]	[]	0	hSpCas9	negative selection	2698997
60649155	60649178	14	+	27260157	HT1080	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.171003564461575	[]	[]	1	hSpCas9	negative selection	2718233
60649090	60649113	14	+	27260157	HT1080	viability	GGAACCTGCCCAGGCGCTCCAGG	SIX1	ENSG00000126778	0.0247988373816775	[]	[]	0	hSpCas9	negative selection	2720624
60649052	60649075	14	+	27260157	HT1080	viability	GTTCTTGTGCAGGTGGTCGCAGG	SIX1	ENSG00000126778	-0.164443227891441	[]	[]	0	hSpCas9	negative selection	2721886
60649013	60649036	14	+	27260157	HT1080	viability	GTGGAAGGCGACCACCGCCTTGG	SIX1	ENSG00000126778	-0.570879713135672	[]	[]	-7	hSpCas9	negative selection	2722954
60649036	60649059	14	-	27260157	HT1080	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.0261512413144365	[]	[]	0	hSpCas9	negative selection	2724205
60649024	60649047	14	-	27260157	MKN45	viability	CGTACTCAAGGCCAAGGCGGTGG	SIX1	ENSG00000126778	-0.460996888700832	[]	[]	-6	hSpCas9	negative selection	2728688
60649116	60649139	14	-	27260157	MKN45	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.756455405258372	[]	[]	7	hSpCas9	negative selection	2730374
60649069	60649092	14	+	27260157	MKN45	viability	CGCAGGCGGGCAGTGACCACAGG	SIX1	ENSG00000126778	-1.10180832448814	[]	[]	-8	hSpCas9	negative selection	2732358
60649169	60649192	14	+	27260157	MKN45	viability	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.0792756630857198	[]	[]	0	hSpCas9	negative selection	2733260
60649108	60649131	14	-	27260157	MKN45	viability	TCTGCAGCAAGGCGGAAACCTGG	SIX1	ENSG00000126778	-0.286282494417083	[]	[]	-1	hSpCas9	negative selection	2734778
60648949	60648972	14	+	27260157	MKN45	viability	GGTGGTTGTGAGGCGAGAACTGG	SIX1	ENSG00000126778	-1.4682110540069	[]	[]	-8	hSpCas9	negative selection	2736050
60649098	60649121	14	-	27260157	MKN45	viability	GGCGGAAACCTGGAGCGCCTGGG	SIX1	ENSG00000126778	0.276709102066919	[]	[]	5	hSpCas9	negative selection	2737867
60649042	60649065	14	+	27260157	MKN45	viability	GTACGCTCTCGTTCTTGTGCAGG	SIX1	ENSG00000126778	-1.95865446971547	[]	[]	-9	hSpCas9	negative selection	2739240
60649085	60649108	14	-	27260157	MKN45	viability	AGCGCCTGGGCAGGTTCCTGTGG	SIX1	ENSG00000126778	-0.42381625590327	[]	[]	-6	hSpCas9	negative selection	2756953
60648926	60648949	14	+	27260157	MKN45	viability	CAGCCACAGTTGCTGCAGTTTGG	SIX1	ENSG00000126778	0.85391304567244	[]	[]	8	hSpCas9	negative selection	2757217
60648922	60648945	14	-	27260157	MKN45	viability	ACTGCAGCAACTGTGGCTGAAGG	SIX1	ENSG00000126778	0.711064193277672	[]	[]	7	hSpCas9	negative selection	2758499
60649147	60649170	14	-	27260157	MKN45	viability	TGGCTTTACGCAGGAGCAAGTGG	SIX1	ENSG00000126778	-1.10722875497208	[]	[]	-8	hSpCas9	negative selection	2760456
60649081	60649104	14	+	27260157	MKN45	viability	GTGACCACAGGAACCTGCCCAGG	SIX1	ENSG00000126778	0.768583913384226	[]	[]	7	hSpCas9	negative selection	2765980
60649008	60649031	14	-	27260157	MKN45	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.291467242824585	[]	[]	5	hSpCas9	negative selection	2771302
60649167	60649190	14	-	27260157	MKN45	viability	ATGTCGATGCTGCCGTCGTTTGG	SIX1	ENSG00000126778	0.1046846043898	[]	[]	0	hSpCas9	negative selection	2775127
60649155	60649178	14	+	27260157	MKN45	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.667408523187888	[]	[]	7	hSpCas9	negative selection	2794363
60649090	60649113	14	+	27260157	MKN45	viability	GGAACCTGCCCAGGCGCTCCAGG	SIX1	ENSG00000126778	-0.434831857297386	[]	[]	-6	hSpCas9	negative selection	2796754
60649052	60649075	14	+	27260157	MKN45	viability	GTTCTTGTGCAGGTGGTCGCAGG	SIX1	ENSG00000126778	-1.55505720543512	[]	[]	-9	hSpCas9	negative selection	2798016
60649013	60649036	14	+	27260157	MKN45	viability	GTGGAAGGCGACCACCGCCTTGG	SIX1	ENSG00000126778	1.5299652697758	[]	[]	9	hSpCas9	negative selection	2799084
60649036	60649059	14	-	27260157	MKN45	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	0.472019662110044	[]	[]	6	hSpCas9	negative selection	2800335
60649024	60649047	14	-	27260157	RKO	viability	CGTACTCAAGGCCAAGGCGGTGG	SIX1	ENSG00000126778	-0.0880394661396612	[]	[]	0	hSpCas9	negative selection	2804818
60649116	60649139	14	-	27260157	RKO	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	-0.0467353986451252	[]	[]	0	hSpCas9	negative selection	2806504
60649069	60649092	14	+	27260157	RKO	viability	CGCAGGCGGGCAGTGACCACAGG	SIX1	ENSG00000126778	0.124535855203448	[]	[]	0	hSpCas9	negative selection	2808488
60649169	60649192	14	+	27260157	RKO	viability	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	1.05445984269978	[]	[]	9	hSpCas9	negative selection	2809390
60649108	60649131	14	-	27260157	RKO	viability	TCTGCAGCAAGGCGGAAACCTGG	SIX1	ENSG00000126778	-0.750098356851377	[]	[]	-7	hSpCas9	negative selection	2810908
60648949	60648972	14	+	27260157	RKO	viability	GGTGGTTGTGAGGCGAGAACTGG	SIX1	ENSG00000126778	0.0637552655676319	[]	[]	0	hSpCas9	negative selection	2812180
60649098	60649121	14	-	27260157	RKO	viability	GGCGGAAACCTGGAGCGCCTGGG	SIX1	ENSG00000126778	0.317713980770025	[]	[]	1	hSpCas9	negative selection	2813997
60649042	60649065	14	+	27260157	RKO	viability	GTACGCTCTCGTTCTTGTGCAGG	SIX1	ENSG00000126778	-1.38570080082474	[]	[]	-8	hSpCas9	negative selection	2815370
60649085	60649108	14	-	27260157	RKO	viability	AGCGCCTGGGCAGGTTCCTGTGG	SIX1	ENSG00000126778	-0.885987723690833	[]	[]	-8	hSpCas9	negative selection	2833083
60648926	60648949	14	+	27260157	RKO	viability	CAGCCACAGTTGCTGCAGTTTGG	SIX1	ENSG00000126778	0.452114638401352	[]	[]	2	hSpCas9	negative selection	2833347
60648922	60648945	14	-	27260157	RKO	viability	ACTGCAGCAACTGTGGCTGAAGG	SIX1	ENSG00000126778	1.44367413780426	[]	[]	9	hSpCas9	negative selection	2834629
60649147	60649170	14	-	27260157	RKO	viability	TGGCTTTACGCAGGAGCAAGTGG	SIX1	ENSG00000126778	-0.312693134336082	[]	[]	-6	hSpCas9	negative selection	2836586
60649081	60649104	14	+	27260157	RKO	viability	GTGACCACAGGAACCTGCCCAGG	SIX1	ENSG00000126778	0.812138248920266	[]	[]	8	hSpCas9	negative selection	2842110
60649008	60649031	14	-	27260157	RKO	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.892096906361101	[]	[]	8	hSpCas9	negative selection	2847432
60649167	60649190	14	-	27260157	RKO	viability	ATGTCGATGCTGCCGTCGTTTGG	SIX1	ENSG00000126778	0.742715176743822	[]	[]	8	hSpCas9	negative selection	2851257
60649155	60649178	14	+	27260157	RKO	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.424412058510267	[]	[]	2	hSpCas9	negative selection	2870493
60649090	60649113	14	+	27260157	RKO	viability	GGAACCTGCCCAGGCGCTCCAGG	SIX1	ENSG00000126778	0.481595454536087	[]	[]	2	hSpCas9	negative selection	2872884
60649052	60649075	14	+	27260157	RKO	viability	GTTCTTGTGCAGGTGGTCGCAGG	SIX1	ENSG00000126778	-0.0136850891064973	[]	[]	0	hSpCas9	negative selection	2874146
60649013	60649036	14	+	27260157	RKO	viability	GTGGAAGGCGACCACCGCCTTGG	SIX1	ENSG00000126778	1.16582101379928	[]	[]	9	hSpCas9	negative selection	2875214
60649036	60649059	14	-	27260157	RKO	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	0.0431793448500521	[]	[]	0	hSpCas9	negative selection	2876465
60649024	60649047	14	-	27260157	SF268	viability	CGTACTCAAGGCCAAGGCGGTGG	SIX1	ENSG00000126778	0.665395911789605	[]	[]	8	hSpCas9	negative selection	2880948
60649116	60649139	14	-	27260157	SF268	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.132473577904294	[]	[]	0	hSpCas9	negative selection	2882634
60649069	60649092	14	+	27260157	SF268	viability	CGCAGGCGGGCAGTGACCACAGG	SIX1	ENSG00000126778	-0.407998112645111	[]	[]	-3	hSpCas9	negative selection	2884618
60649169	60649192	14	+	27260157	SF268	viability	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	1.04477725186915	[]	[]	9	hSpCas9	negative selection	2885520
60649108	60649131	14	-	27260157	SF268	viability	TCTGCAGCAAGGCGGAAACCTGG	SIX1	ENSG00000126778	-0.558179221451935	[]	[]	-4	hSpCas9	negative selection	2887038
60648949	60648972	14	+	27260157	SF268	viability	GGTGGTTGTGAGGCGAGAACTGG	SIX1	ENSG00000126778	-0.362157097421527	[]	[]	-3	hSpCas9	negative selection	2888310
60649098	60649121	14	-	27260157	SF268	viability	GGCGGAAACCTGGAGCGCCTGGG	SIX1	ENSG00000126778	0.187994557184807	[]	[]	0	hSpCas9	negative selection	2890127
60649042	60649065	14	+	27260157	SF268	viability	GTACGCTCTCGTTCTTGTGCAGG	SIX1	ENSG00000126778	-1.29746232302128	[]	[]	-7	hSpCas9	negative selection	2891500
60649085	60649108	14	-	27260157	SF268	viability	AGCGCCTGGGCAGGTTCCTGTGG	SIX1	ENSG00000126778	0.214337003748164	[]	[]	3	hSpCas9	negative selection	2909213
60648926	60648949	14	+	27260157	SF268	viability	CAGCCACAGTTGCTGCAGTTTGG	SIX1	ENSG00000126778	0.387357860309402	[]	[]	4	hSpCas9	negative selection	2909477
60648922	60648945	14	-	27260157	SF268	viability	ACTGCAGCAACTGTGGCTGAAGG	SIX1	ENSG00000126778	0.758611189290826	[]	[]	8	hSpCas9	negative selection	2910759
60649147	60649170	14	-	27260157	SF268	viability	TGGCTTTACGCAGGAGCAAGTGG	SIX1	ENSG00000126778	-0.478098142480196	[]	[]	-4	hSpCas9	negative selection	2912716
60649081	60649104	14	+	27260157	SF268	viability	GTGACCACAGGAACCTGCCCAGG	SIX1	ENSG00000126778	0.90012881262307	[]	[]	9	hSpCas9	negative selection	2918240
60649008	60649031	14	-	27260157	SF268	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.987511025045006	[]	[]	9	hSpCas9	negative selection	2923562
60649167	60649190	14	-	27260157	SF268	viability	ATGTCGATGCTGCCGTCGTTTGG	SIX1	ENSG00000126778	-0.20786609132135	[]	[]	-2	hSpCas9	negative selection	2927387
60649155	60649178	14	+	27260157	SF268	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.560999711241527	[]	[]	8	hSpCas9	negative selection	2946623
60649090	60649113	14	+	27260157	SF268	viability	GGAACCTGCCCAGGCGCTCCAGG	SIX1	ENSG00000126778	1.9708843906447	[]	[]	9	hSpCas9	negative selection	2949014
60649052	60649075	14	+	27260157	SF268	viability	GTTCTTGTGCAGGTGGTCGCAGG	SIX1	ENSG00000126778	-0.375696605802396	[]	[]	-3	hSpCas9	negative selection	2950276
60649013	60649036	14	+	27260157	SF268	viability	GTGGAAGGCGACCACCGCCTTGG	SIX1	ENSG00000126778	0.833107902838813	[]	[]	9	hSpCas9	negative selection	2951344
60649036	60649059	14	-	27260157	SF268	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.104642942785369	[]	[]	-1	hSpCas9	negative selection	2952595
60648992	60649015	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAGCTCACGGAAGTTGCCGCGG	SIX1	ENSG00000126778	-0.017718867387836207	[3,2]	[2,2]	0	hSpCas9	positive selection	3020414
60648855	60648878	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.01048167130700084	[2,2]	[1,2]	0	hSpCas9	positive selection	3020415
60649008	60649031	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.003064037243340867	[3,2]	[1,2]	0	hSpCas9	positive selection	3020416
60649156	60649179	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.02703904059673052	[3,3]	[2,3]	0	hSpCas9	positive selection	3020417
60648992	60649015	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAGCTCACGGAAGTTGCCGCGG	SIX1	ENSG00000126778	0.090607595571303	[3,3]	[1,2]	1	hSpCas9	positive selection	3088272
60648855	60648878	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.2997665408788602	[2,2]	[2,1]	5	hSpCas9	positive selection	3088273
60649008	60649031	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	-0.014177687580270208	[3,3]	[3,1]	0	hSpCas9	positive selection	3088274
60649156	60649179	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.3860051290789508	[3,3]	[3,0]	-5	hSpCas9	positive selection	3088275
60648725	60648748		-	24336571	A375	resistance to PLX after 7 days	ACCCATCGCCGCGTGAGAAGCGG	SIX1	ENSG00000126778	-0.37747351561883913	[8,7]	[7,4]	-9	hSpCas9	positive selection	3144370
60646447	60646470		+	24336571	A375	resistance to PLX after 7 days	CCGAGTTCTGGTCTGGACTTTGG	SIX1	ENSG00000126778	0.1111764907460715	[14,15]	[15,16]	3	hSpCas9	positive selection	3144371
60648754	60648777		+	24336571	A375	resistance to PLX after 7 days	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.04460768573558194	[33,31]	[31,35]	1	hSpCas9	positive selection	3144372
60648725	60648748		-	24336571	A375	resistance to PLX after 14 days	ACCCATCGCCGCGTGAGAAGCGG	SIX1	ENSG00000126778	-0.08840173814818442	[5,7]	[1,2]	-1	hSpCas9	positive selection	3202163
60646447	60646470		+	24336571	A375	resistance to PLX after 14 days	CCGAGTTCTGGTCTGGACTTTGG	SIX1	ENSG00000126778	-1.1348172485548234	[16,23]	[3,3]	-9	hSpCas9	positive selection	3202164
60648754	60648777		+	24336571	A375	resistance to PLX after 14 days	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.4323156920156217	[35,34]	[13,9]	-5	hSpCas9	positive selection	3202165
60648725	60648748		-	24336571	A375	viability after 7 days	ACCCATCGCCGCGTGAGAAGCGG	SIX1	ENSG00000126778	-0.14477687336766737	[9]	[8,7]	-2	hSpCas9	negative selection	3259956
60646447	60646470		+	24336571	A375	viability after 7 days	CCGAGTTCTGGTCTGGACTTTGG	SIX1	ENSG00000126778	0.43876968199260036	[11]	[14,15]	6	hSpCas9	negative selection	3259957
60648754	60648777		+	24336571	A375	viability after 7 days	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.034191217750015435	[33]	[33,31]	0	hSpCas9	negative selection	3259958
60648725	60648748		-	24336571	A375	viability after 14 days	ACCCATCGCCGCGTGAGAAGCGG	SIX1	ENSG00000126778	-0.39087115967456915	[9]	[5,7]	-5	hSpCas9	negative selection	3317749
60646447	60646470		+	24336571	A375	viability after 14 days	CCGAGTTCTGGTCTGGACTTTGG	SIX1	ENSG00000126778	0.857182748504818	[11]	[16,23]	9	hSpCas9	negative selection	3317750
60648754	60648777		+	24336571	A375	viability after 14 days	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.14449600085676906	[33]	[35,34]	1	hSpCas9	negative selection	3317751
60646503	60646526	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	0.6426163673306269	[97,97]	[0,0]	3	hSpCas9	positive selection	3392529
60649036	60649059	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	0.2915419267837481	[124,124]	[0,0]	1	hSpCas9	positive selection	3392530
60648860	60648883	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.7130056952220246	[279,279]	[2,2]	3	hSpCas9	positive selection	3392531
60648991	60649014	14	+	26780180	HT29	viability (Avana library 4 designs)	AGAGCTCACGGAAGTTGCCGCGG	SIX1	ENSG00000126778	1.72579416009923	[]	[]	6	hSpCas9	negative selection	3458926
60648854	60648877	14	+	26780180	HT29	viability (Avana library 4 designs)	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	1.31042758040509	[]	[]	5	hSpCas9	negative selection	3458927
60649008	60649031	14	-	26780180	HT29	viability (Avana library 4 designs)	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.26717567482904	[]	[]	5	hSpCas9	negative selection	3458928
60649155	60649178	14	+	26780180	HT29	viability (Avana library 4 designs)	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	1.41253912885014	[]	[]	5	hSpCas9	negative selection	3458929
60649155	60649178	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.957101465176852	[]	[]	1	hSpCas9	negative selection	3558603
60648991	60649014	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGCTCACGGAAGTTGCCGCGG	SIX1	ENSG00000126778	0.263995162995189	[]	[]	0	hSpCas9	negative selection	3558604
60649008	60649031	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	7.43968200325936	[]	[]	9	hSpCas9	negative selection	3558605
60648854	60648877	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	1.22419881528536	[]	[]	1	hSpCas9	negative selection	3558606
60648780	60648803	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	2.57920596529341	[]	[]	4	hSpCas9	negative selection	3558607
60648907	60648930	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	2.3957372149986	[]	[]	3	hSpCas9	negative selection	3558608
60649155	60649178	14	+	26780180	A375	viability (Avana lentiGuide)	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	2.31210065076257	[]	[]	2	hSpCas9	negative selection	3667262
60648991	60649014	14	+	26780180	A375	viability (Avana lentiGuide)	AGAGCTCACGGAAGTTGCCGCGG	SIX1	ENSG00000126778	14.1597180987331	[]	[]	8	hSpCas9	negative selection	3667263
60649008	60649031	14	-	26780180	A375	viability (Avana lentiGuide)	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	-5.66386033965547	[]	[]	-8	hSpCas9	negative selection	3667264
60648854	60648877	14	+	26780180	A375	viability (Avana lentiGuide)	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	10.8885730011818	[]	[]	7	hSpCas9	negative selection	3667265
60648780	60648803	14	-	26780180	A375	viability (Avana lentiGuide)	TGCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	9.72481382398337	[]	[]	6	hSpCas9	negative selection	3667266
60648907	60648930	14	-	26780180	A375	viability (Avana lentiGuide)	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	6.92185794847553	[]	[]	5	hSpCas9	negative selection	3667267
60649155	60649178	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.0021448312697891986	[5]	[4,5]	0	hSpCas9	positive selection	3775869
60648991	60649014	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGCTCACGGAAGTTGCCGCGG	SIX1	ENSG00000126778	-0.09097370674862967	[4]	[4,3]	-1	hSpCas9	positive selection	3775870
60649008	60649031	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.35620919183773014	[4]	[5,5]	9	hSpCas9	positive selection	3775871
60648854	60648877	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.21129888329318253	[3]	[3,4]	6	hSpCas9	positive selection	3775872
60648780	60648803	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	0.13528804720432475	[4]	[5,4]	3	hSpCas9	positive selection	3775873
60648907	60648930	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.11973620813872854	[4]	[3,4]	-2	hSpCas9	positive selection	3775874
60649155	60649178	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.1282797014809845	[5]	[3,4]	-2	hSpCas9	positive selection	3884476
60648991	60649014	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGCTCACGGAAGTTGCCGCGG	SIX1	ENSG00000126778	-1.5897628995047974	[5]	[0,0]	-9	hSpCas9	positive selection	3884477
60649008	60649031	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.25847065968404054	[4]	[4,5]	7	hSpCas9	positive selection	3884478
60648854	60648877	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	-1.168704003871033	[4]	[0,0]	-8	hSpCas9	positive selection	3884479
60648780	60648803	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	-0.38410637150993454	[4]	[0,4]	-5	hSpCas9	positive selection	3884480
60648907	60648930	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.38537889520695046	[5]	[3,2]	-5	hSpCas9	positive selection	3884481
60646503	60646526	14	+	26780180	A375	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	1.4144797595543	[]	[]	7	hSpCas9	negative selection	3994532
60649036	60649059	14	-	26780180	A375	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	1.78094012062082	[]	[]	9	hSpCas9	negative selection	3994533
60646371	60646394	14	+	26780180	A375	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.74848581730622	[]	[]	2	hSpCas9	negative selection	3994534
60649155	60649178	14	+	26780180	A375	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.964635213003454	[]	[]	4	hSpCas9	negative selection	3994535
60648860	60648883	14	-	26780180	A375	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	1.11938026458412	[]	[]	5	hSpCas9	negative selection	3994536
60648754	60648777	14	+	26780180	A375	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	1.50630173790658	[]	[]	8	hSpCas9	negative selection	3994537
60646503	60646526	14	+	26780180	HT29	viability (GeCKOv2 library)	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	1.13971477481866	[]	[]	5	hSpCas9	negative selection	4102498
60649036	60649059	14	-	26780180	HT29	viability (GeCKOv2 library)	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	2.22770180880313	[]	[]	9	hSpCas9	negative selection	4102499
60646371	60646394	14	+	26780180	HT29	viability (GeCKOv2 library)	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	1.08717240121229	[]	[]	5	hSpCas9	negative selection	4102500
60649155	60649178	14	+	26780180	HT29	viability (GeCKOv2 library)	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.678056523875384	[]	[]	2	hSpCas9	negative selection	4102501
60648860	60648883	14	-	26780180	HT29	viability (GeCKOv2 library)	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	1.51913166509277	[]	[]	7	hSpCas9	negative selection	4102502
60648754	60648777	14	+	26780180	HT29	viability (GeCKOv2 library)	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	2.25075755211985	[]	[]	9	hSpCas9	negative selection	4102503
60648725	60648748	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCCATCGCCGCGTGAGAAGCGG	SIX1	ENSG00000126778	0.024476495192904735	[2]	[1,1]	0	hSpCas9	positive selection	4170322
60646447	60646470	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGAGTTCTGGTCTGGACTTTGG	SIX1	ENSG00000126778	0.10893731406897164	[3]	[2,1]	2	hSpCas9	positive selection	4170323
60648754	60648777	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.11816250743378381	[4]	[3,3]	3	hSpCas9	positive selection	4170324
60648725	60648748	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCCATCGCCGCGTGAGAAGCGG	SIX1	ENSG00000126778	-0.6662347219934757	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4234344
60646447	60646470	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGAGTTCTGGTCTGGACTTTGG	SIX1	ENSG00000126778	-0.46579147251598185	[4]	[0,2,0,0]	-6	hSpCas9	positive selection	4234345
60648754	60648777	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.11680689473874356	[4]	[4,2,2,0]	0	hSpCas9	positive selection	4234346
60648754	60648777	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.08060888531192296	[3]	[2,2]	-1	hSpCas9	positive selection	4297873
60649155	60649178	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.1513006100761217	[2]	[2,0]	-3	hSpCas9	positive selection	4297874
60646371	60646394	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-8.698739203139016e-05	[1]	[1,1]	0	hSpCas9	positive selection	4297875
60646503	60646526	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.29010662483403094	[2]	[2,0]	-6	hSpCas9	positive selection	4362127
60649036	60649059	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.5718524761829925	[2]	[1,0]	-8	hSpCas9	positive selection	4362128
60648860	60648883	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.06503152162871159	[3]	[3,2]	1	hSpCas9	positive selection	4362129
60648640	60648662	14	-	27760321	OCIAML3	viability	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	0.5961022389743265	[756,565]	[770,780]	7	hSpCas9	negative selection	4439132
60648725	60648747	14	+	27760321	OCIAML3	viability	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-0.28160032622576514	[112,139]	[41,134]	-3	hSpCas9	negative selection	4439133
60648755	60648777	14	+	27760321	OCIAML3	viability	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.11981223217164438	[1081,1017]	[836,965]	1	hSpCas9	negative selection	4439134
60648780	60648802	14	-	27760321	OCIAML3	viability	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	0.6033597560499931	[189,194]	[217,244]	7	hSpCas9	negative selection	4439135
60648907	60648929	14	-	27760321	OCIAML3	viability	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.326965690371812	[495,444]	[345,610]	4	hSpCas9	negative selection	4439136
60648640	60648662	14	-	27760321	OCIAML2	viability	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	0.28825184853678254	[756,565]	[602,706]	4	hSpCas9	negative selection	4522595
60648725	60648747	14	+	27760321	OCIAML2	viability	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	0.6597054100750184	[112,139]	[157,170]	8	hSpCas9	negative selection	4522596
60648755	60648777	14	+	27760321	OCIAML2	viability	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.059718942937704744	[1081,1017]	[664,1013]	-1	hSpCas9	negative selection	4522597
60648780	60648802	14	-	27760321	OCIAML2	viability	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	1.1381862720820934	[189,194]	[307,391]	9	hSpCas9	negative selection	4522598
60648907	60648929	14	-	27760321	OCIAML2	viability	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.4504018613496653	[495,444]	[449,610]	6	hSpCas9	negative selection	4522599
60648640	60648662	14	-	27760321	MV411	viability	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	0.8861764304928863	[756,565]	[683,973]	6	hSpCas9	negative selection	4606058
60648725	60648747	14	+	27760321	MV411	viability	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-0.18008675315882483	[112,139]	[36,130]	-1	hSpCas9	negative selection	4606059
60648755	60648777	14	+	27760321	MV411	viability	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.10839773689711785	[1081,1017]	[683,842]	0	hSpCas9	negative selection	4606060
60648780	60648802	14	-	27760321	MV411	viability	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	-0.6740282912139755	[189,194]	[35,145]	-4	hSpCas9	negative selection	4606061
60648907	60648929	14	-	27760321	MV411	viability	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.23362565710058628	[495,444]	[167,659]	1	hSpCas9	negative selection	4606062
60648640	60648662	14	-	27760321	HL60	viability	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	0.5382809277413583	[756,565]	[877,671]	6	hSpCas9	negative selection	4689521
60648725	60648747	14	+	27760321	HL60	viability	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-0.7146960579106989	[112,139]	[37,90]	-6	hSpCas9	negative selection	4689522
60648755	60648777	14	+	27760321	HL60	viability	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.36275216400025045	[1081,1017]	[1162,1040]	4	hSpCas9	negative selection	4689523
60648780	60648802	14	-	27760321	HL60	viability	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	0.06571238060540407	[189,194]	[174,154]	0	hSpCas9	negative selection	4689524
60648907	60648929	14	-	27760321	HL60	viability	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.5917948156426819	[495,444]	[464,698]	7	hSpCas9	negative selection	4689525
60648640	60648662	14	-	27760321	HT1080	viability	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	-0.3864870745993801	[565,441]	[239,58]	-2	hSpCas9	negative selection	4772984
60648725	60648747	14	+	27760321	HT1080	viability	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-1.3052724674144167	[139,108]	[31,6]	-5	hSpCas9	negative selection	4772985
60648755	60648777	14	+	27760321	HT1080	viability	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.6007685620495771	[1017,794]	[603,485]	3	hSpCas9	negative selection	4772986
60648780	60648802	14	-	27760321	HT1080	viability	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	-1.2918856581357674	[194,151]	[32,22]	-5	hSpCas9	negative selection	4772987
60648907	60648929	14	-	27760321	HT1080	viability	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.9391350872062365	[444,346]	[87,75]	-4	hSpCas9	negative selection	4772988
60648640	60648662	14	-	27760321	HT29	viability after 7 days	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	0.5463213318428564	[565,441]	[1290,623,970]	8	hSpCas9	negative selection	4856447
60648725	60648747	14	+	27760321	HT29	viability after 7 days	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-0.7048095625659723	[139,108]	[162,20,118]	-7	hSpCas9	negative selection	4856448
60648755	60648777	14	+	27760321	HT29	viability after 7 days	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.26744901365977536	[1017,794]	[1498,1525,1201]	4	hSpCas9	negative selection	4856449
60648780	60648802	14	-	27760321	HT29	viability after 7 days	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	-0.08895987976974462	[194,151]	[361,92,195]	-1	hSpCas9	negative selection	4856450
60648907	60648929	14	-	27760321	HT29	viability after 7 days	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.0384279311924708	[444,346]	[286,682,486]	0	hSpCas9	negative selection	4856451
60648640	60648662	14	-	27760321	HT29	viability after 25 days	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	0.7478926697008834	[565,441]	[983,873,1049]	8	hSpCas9	negative selection	4939910
60648725	60648747	14	+	27760321	HT29	viability after 25 days	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-1.190675127679279	[139,108]	[77,35,72]	-7	hSpCas9	negative selection	4939911
60648755	60648777	14	+	27760321	HT29	viability after 25 days	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.6533827021398879	[1017,794]	[1390,1199,2388]	7	hSpCas9	negative selection	4939912
60648780	60648802	14	-	27760321	HT29	viability after 25 days	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	0.3370368298399439	[194,151]	[215,278,258]	3	hSpCas9	negative selection	4939913
60648907	60648929	14	-	27760321	HT29	viability after 25 days	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.10552832636002321	[444,346]	[369,390,512]	-1	hSpCas9	negative selection	4939914
60648640	60648662	14	-	27760321	HT29	viability after 22 days	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	0.7366403476757906	[565,441]	[931,770,1212]	8	hSpCas9	negative selection	5023373
60648725	60648747	14	+	27760321	HT29	viability after 22 days	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-0.7740170574263694	[139,108]	[67,89,94]	-6	hSpCas9	negative selection	5023374
60648755	60648777	14	+	27760321	HT29	viability after 22 days	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.40037380607032524	[1017,794]	[1284,1086,1783]	4	hSpCas9	negative selection	5023375
60648780	60648802	14	-	27760321	HT29	viability after 22 days	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	0.5149159584057041	[194,151]	[243,317,298]	5	hSpCas9	negative selection	5023376
60648907	60648929	14	-	27760321	HT29	viability after 22 days	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.25116151347029997	[444,346]	[304,363,487]	-3	hSpCas9	negative selection	5023377
60648640	60648662	14	-	27760321	HT29	viability after 19 days	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	0.9411911802800992	[565,441]	[1480,854,1025]	8	hSpCas9	negative selection	5106836
60648725	60648747	14	+	27760321	HT29	viability after 19 days	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-0.6467822511579551	[139,108]	[105,95,72]	-5	hSpCas9	negative selection	5106837
60648755	60648777	14	+	27760321	HT29	viability after 19 days	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.5146475106360822	[1017,794]	[1913,1095,1477]	5	hSpCas9	negative selection	5106838
60648780	60648802	14	-	27760321	HT29	viability after 19 days	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	0.5690873406415915	[194,151]	[132,545,190]	6	hSpCas9	negative selection	5106839
60648907	60648929	14	-	27760321	HT29	viability after 19 days	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.6150719882817682	[444,346]	[217,372,287]	-5	hSpCas9	negative selection	5106840
60648640	60648662	14	-	27760321	HT29	viability after 16 days	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	0.5192266033743711	[565,441]	[1008,591,847]	6	hSpCas9	negative selection	5190299
60648725	60648747	14	+	27760321	HT29	viability after 16 days	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-1.0389177066750366	[139,108]	[46,81,71]	-7	hSpCas9	negative selection	5190300
60648755	60648777	14	+	27760321	HT29	viability after 16 days	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.261396978371111	[1017,794]	[1412,891,1368]	3	hSpCas9	negative selection	5190301
60648780	60648802	14	-	27760321	HT29	viability after 16 days	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	0.49521489273264097	[194,151]	[268,360,187]	5	hSpCas9	negative selection	5190302
60648907	60648929	14	-	27760321	HT29	viability after 16 days	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.08165600477515425	[444,346]	[343,414,636]	0	hSpCas9	negative selection	5190303
60648640	60648662	14	-	27760321	HT29	viability after 13 days	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	0.7970662813189582	[565,441]	[1096,856,1088]	9	hSpCas9	negative selection	5273762
60648725	60648747	14	+	27760321	HT29	viability after 13 days	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-2.0285094761713367	[139,108]	[43,23,37]	-8	hSpCas9	negative selection	5273763
60648755	60648777	14	+	27760321	HT29	viability after 13 days	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.1039497892646728	[1017,794]	[1465,831,1093]	1	hSpCas9	negative selection	5273764
60648780	60648802	14	-	27760321	HT29	viability after 13 days	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	0.36999424311955853	[194,151]	[262,286,231]	5	hSpCas9	negative selection	5273765
60648907	60648929	14	-	27760321	HT29	viability after 13 days	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.04434546820824663	[444,346]	[210,494,619]	0	hSpCas9	negative selection	5273766
60648640	60648662	14	-	27760321	HT29	viability after 10 days	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	0.6278329748893854	[565,441]	[1114,866,932]	8	hSpCas9	negative selection	5357225
60648725	60648747	14	+	27760321	HT29	viability after 10 days	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-1.0415015932046445	[139,108]	[102,52,69]	-8	hSpCas9	negative selection	5357226
60648755	60648777	14	+	27760321	HT29	viability after 10 days	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.22870753428988833	[1017,794]	[1201,1087,1673]	3	hSpCas9	negative selection	5357227
60648780	60648802	14	-	27760321	HT29	viability after 10 days	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	0.17270964861750593	[194,151]	[296,191,241]	2	hSpCas9	negative selection	5357228
60648907	60648929	14	-	27760321	HT29	viability after 10 days	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.03877620373020965	[444,346]	[266,544,707]	0	hSpCas9	negative selection	5357229
60648640	60648662	14	-	27760321	MOLM13	viability	CAAAGAGACCGGGCCGCGGAGG	SIX1	ENSG00000126778	1.0671486725687185	[756,565]	[1268,354]	7	hSpCas9	negative selection	5440688
60648725	60648747	14	+	27760321	MOLM13	viability	CCGCTTCTCACGCGGCGATGGG	SIX1	ENSG00000126778	-0.7402038202137198	[112,139]	[39,45]	-4	hSpCas9	negative selection	5440689
60648755	60648777	14	+	27760321	MOLM13	viability	GTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.3869569791981373	[1081,1017]	[865,697]	2	hSpCas9	negative selection	5440690
60648780	60648802	14	-	27760321	MOLM13	viability	GCTTCAAGGAGAAGTCGAGGGG	SIX1	ENSG00000126778	1.164188484924302	[189,194]	[392,117]	7	hSpCas9	negative selection	5440691
60648907	60648929	14	-	27760321	MOLM13	viability	CTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.2105448961667652	[495,444]	[159,287]	-1	hSpCas9	negative selection	5440692
60649342	60649365	14	+	27661255	K562	viability	GTGGGCGGCCAAGGAAGAGAAGG	SIX1	ENSG00000126778	-0.22490849085246611	[495,467]	[379,286]	-6	dCas9-KRAB	negative selection	5511173
60649376	60649399	14	+	27661255	K562	viability	GGGAGGTTCTGGACACGGAACGG	SIX1	ENSG00000126778	0.0884007061103873	[1195,1091]	[1112,853]	3	dCas9-KRAB	negative selection	5511174
60649098	60649121	14	-	27661255	K562	viability	GGCGGAAACCTGGAGCGCCTGGG	SIX1	ENSG00000126778	0.1781679326980194	[958,1064]	[1001,836]	6	dCas9-KRAB	negative selection	5511175
60649424	60649447	14	-	27661255	K562	viability	GCGGGAGGTCGGAGGCAGCAAGG	SIX1	ENSG00000126778	0.2025930706517156	[1707,1792]	[1638,1580]	7	dCas9-KRAB	negative selection	5511176
60648754	60648777	14	+	27260156	BXPC3	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.11966101927169981	[743]	[608,573,736,993]	-3	hSpCas9	negative selection	5570333
60649155	60649178	14	+	27260156	BXPC3	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.1997331601224268	[286]	[213,317,354,527]	4	hSpCas9	negative selection	5570334
60646371	60646394	14	+	27260156	BXPC3	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.07303876360223183	[185]	[165,180,178,308]	1	hSpCas9	negative selection	5570335
60646503	60646526	14	+	27260156	BXPC3	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.2360435732757904	[245]	[206,230,194,241]	-5	hSpCas9	negative selection	5634587
60649036	60649059	14	-	27260156	BXPC3	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.6139125589410482	[424]	[305,289,223,342]	-8	hSpCas9	negative selection	5634588
60648860	60648883	14	-	27260156	BXPC3	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.17112474492567842	[698]	[767,773,779,992]	4	hSpCas9	negative selection	5634589
60648754	60648777	14	+	27260156	A673	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.11888728530682269	[743]	[867,795,707,929]	-3	hSpCas9	negative selection	5691584
60649155	60649178	14	+	27260156	A673	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.014222534280793231	[286]	[373,297,282,418]	0	hSpCas9	negative selection	5691585
60646371	60646394	14	+	27260156	A673	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.22785954894406268	[185]	[247,160,155,205]	-5	hSpCas9	negative selection	5691586
60646503	60646526	14	+	27260156	A673	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.1621049136844559	[245]	[266,253,357,170]	-4	hSpCas9	negative selection	5755838
60649036	60649059	14	-	27260156	A673	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.47923137636056823	[424]	[398,401,241,427]	-8	hSpCas9	negative selection	5755839
60648860	60648883	14	-	27260156	A673	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.07297260627955099	[698]	[850,773,788,781]	-2	hSpCas9	negative selection	5755840
60648754	60648777	14	+	27260156	A375	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.01556108834978398	[743]	[1120,981,655,712]	0	hSpCas9	negative selection	5812835
60649155	60649178	14	+	27260156	A375	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.15539726896095274	[286]	[278,530,300,398]	2	hSpCas9	negative selection	5812836
60646371	60646394	14	+	27260156	A375	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.028208372576849383	[185]	[163,306,151,237]	0	hSpCas9	negative selection	5812837
60646503	60646526	14	+	27260156	A375	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.4262332207893582	[245]	[169,332,294,87]	-5	hSpCas9	negative selection	5877089
60649036	60649059	14	-	27260156	A375	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.8663857380989953	[424]	[162,322,212,381]	-8	hSpCas9	negative selection	5877090
60648860	60648883	14	-	27260156	A375	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.10727122760982066	[698]	[958,888,1192,518]	1	hSpCas9	negative selection	5877091
60648754	60648777	14	+	27260156	COLO741	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.06730900186407796	[743]	[1106,828,807]	-1	hSpCas9	negative selection	5934086
60649155	60649178	14	+	27260156	COLO741	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.19801837525523813	[286]	[297,547,405]	4	hSpCas9	negative selection	5934087
60646371	60646394	14	+	27260156	COLO741	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.09814668337120103	[185]	[206,301,249]	2	hSpCas9	negative selection	5934088
60646503	60646526	14	+	27260156	COLO741	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.26848507314628134	[245]	[244,289,246]	-5	hSpCas9	negative selection	5998340
60649036	60649059	14	-	27260156	COLO741	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.7371673270314394	[424]	[347,270,356]	-9	hSpCas9	negative selection	5998341
60648860	60648883	14	-	27260156	COLO741	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.1588103169628282	[698]	[1055,1124,825]	3	hSpCas9	negative selection	5998342
60648754	60648777	14	+	27260156	CAL120	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.1785764534315114	[743]	[1156,542,804]	-3	hSpCas9	negative selection	6055337
60649155	60649178	14	+	27260156	CAL120	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.3670899541963897	[286]	[393,164,288]	-5	hSpCas9	negative selection	6055338
60646371	60646394	14	+	27260156	CAL120	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.17529746748375152	[185]	[207,185,220]	-3	hSpCas9	negative selection	6055339
60646503	60646526	14	+	27260156	CAL120	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-1.0065988967976915	[245]	[233,65,168]	-8	hSpCas9	negative selection	6119591
60649036	60649059	14	-	27260156	CAL120	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.6282600431802772	[424]	[605,228,232]	-7	hSpCas9	negative selection	6119592
60648860	60648883	14	-	27260156	CAL120	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.12645299616935002	[698]	[806,804,779]	-2	hSpCas9	negative selection	6119593
60648754	60648777	14	+	27260156	CADOES1	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.1667736915550515	[743]	[546,677,598,642]	-3	hSpCas9	negative selection	6176588
60649155	60649178	14	+	27260156	CADOES1	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.2551460302173545	[286]	[245,193,192,262]	-4	hSpCas9	negative selection	6176589
60646371	60646394	14	+	27260156	CADOES1	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.10865570877998287	[185]	[171,101,196,170]	-2	hSpCas9	negative selection	6176590
60646503	60646526	14	+	27260156	CADOES1	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.39601692784471876	[245]	[239,205,136,109]	-6	hSpCas9	negative selection	6240842
60649036	60649059	14	-	27260156	CADOES1	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.6807424849379655	[424]	[263,223,232,265]	-8	hSpCas9	negative selection	6240843
60648860	60648883	14	-	27260156	CADOES1	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.21548701248957264	[698]	[583,541,643,465]	-4	hSpCas9	negative selection	6240844
60648754	60648777	14	+	27260156	EWS502	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.10264061571451455	[743]	[744,666,755,768]	-2	hSpCas9	negative selection	6297839
60649155	60649178	14	+	27260156	EWS502	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.13934678959138502	[286]	[323,313,199,512]	2	hSpCas9	negative selection	6297840
60646371	60646394	14	+	27260156	EWS502	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.30917803859893267	[185]	[132,142,105,263]	-5	hSpCas9	negative selection	6297841
60646503	60646526	14	+	27260156	EWS502	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.4259627720315684	[245]	[184,209,191,187]	-6	hSpCas9	negative selection	6362093
60649036	60649059	14	-	27260156	EWS502	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.3227972791967145	[424]	[354,360,407,311]	-5	hSpCas9	negative selection	6362094
60648860	60648883	14	-	27260156	EWS502	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.13149910445597873	[698]	[591,657,743,721]	-2	hSpCas9	negative selection	6362095
60648754	60648777	14	+	27260156	EW8	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.02031105611073003	[743]	[683,525,671,490]	0	hSpCas9	negative selection	6419090
60649155	60649178	14	+	27260156	EW8	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.020656264655230516	[286]	[314,235,133,283]	0	hSpCas9	negative selection	6419091
60646371	60646394	14	+	27260156	EW8	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.11301960153073587	[185]	[134,169,219,113]	2	hSpCas9	negative selection	6419092
60646503	60646526	14	+	27260156	EW8	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	0.03406577501928654	[245]	[294,179,185,167]	0	hSpCas9	negative selection	6483344
60649036	60649059	14	-	27260156	EW8	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.6115812308912613	[424]	[326,109,180,300]	-8	hSpCas9	negative selection	6483345
60648860	60648883	14	-	27260156	EW8	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.2556503703631737	[698]	[714,434,326,470]	-5	hSpCas9	negative selection	6483346
60648754	60648777	14	+	27260156	CORL105	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.003687930758835445	[743]	[1060,646,908,891]	0	hSpCas9	negative selection	6540341
60649155	60649178	14	+	27260156	CORL105	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.2838366592180643	[286]	[407,452,400,371]	5	hSpCas9	negative selection	6540342
60646371	60646394	14	+	27260156	CORL105	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.02483414834774056	[185]	[249,212,179,208]	0	hSpCas9	negative selection	6540343
60646503	60646526	14	+	27260156	CORL105	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.2523064541966715	[245]	[210,293,278,186]	-5	hSpCas9	negative selection	6604595
60649036	60649059	14	-	27260156	CORL105	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.5377748576281044	[424]	[320,358,425,276]	-7	hSpCas9	negative selection	6604596
60648860	60648883	14	-	27260156	CORL105	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.028717939453579255	[698]	[999,749,825,768]	0	hSpCas9	negative selection	6604597
60648754	60648777	14	+	27260156	HS294T	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.2377303729715523	[743]	[242,411,235,497]	3	hSpCas9	negative selection	6661592
60649155	60649178	14	+	27260156	HS294T	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.18522902125639917	[286]	[75,89,115,112]	-3	hSpCas9	negative selection	6661593
60646371	60646394	14	+	27260156	HS294T	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.20573151493428354	[185]	[48,75,77,43]	-3	hSpCas9	negative selection	6661594
60646503	60646526	14	+	27260156	HS294T	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	0.16063253321330717	[245]	[41,61,265,53]	2	hSpCas9	negative selection	6725846
60649036	60649059	14	-	27260156	HS294T	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.6597517262755527	[424]	[80,126,95,114]	-7	hSpCas9	negative selection	6725847
60648860	60648883	14	-	27260156	HS294T	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.4202082608839768	[698]	[263,447,452,271]	5	hSpCas9	negative selection	6725848
60648754	60648777	14	+	27260156	HCC44	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.372504402328097	[743]	[919,436,730,577]	-5	hSpCas9	negative selection	6782843
60649155	60649178	14	+	27260156	HCC44	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.26295016660149373	[286]	[220,310,447,124]	-4	hSpCas9	negative selection	6782844
60646371	60646394	14	+	27260156	HCC44	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.195491145185533	[185]	[171,128,154,275]	-3	hSpCas9	negative selection	6782845
60646503	60646526	14	+	27260156	HCC44	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.4780368457606654	[245]	[282,141,236,158]	-6	hSpCas9	negative selection	6847097
60649036	60649059	14	-	27260156	HCC44	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.90438149340581	[424]	[412,232,243,153]	-8	hSpCas9	negative selection	6847098
60648860	60648883	14	-	27260156	HCC44	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.06509853093107909	[698]	[853,546,897,779]	-1	hSpCas9	negative selection	6847099
60648754	60648777	14	+	27260156	G402	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.18245696415577928	[743]	[1314,714,1043,1063]	2	hSpCas9	negative selection	6904094
60649155	60649178	14	+	27260156	G402	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.08670927878439771	[286]	[293,364,581,239]	1	hSpCas9	negative selection	6904095
60646371	60646394	14	+	27260156	G402	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.21721007238970724	[185]	[269,145,237,136]	-3	hSpCas9	negative selection	6904096
60646503	60646526	14	+	27260156	G402	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	0.2589600443921083	[245]	[463,469,249,276]	3	hSpCas9	negative selection	6968348
60649036	60649059	14	-	27260156	G402	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.3378463332415276	[424]	[226,106,923,340]	-4	hSpCas9	negative selection	6968349
60648860	60648883	14	-	27260156	G402	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.2541754662466731	[698]	[931,1498,638,1010]	3	hSpCas9	negative selection	6968350
60648754	60648777	14	+	27260156	L33	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.15777844282355313	[743]	[684,276,451,587]	-4	hSpCas9	negative selection	7025345
60649155	60649178	14	+	27260156	L33	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.191059891203184	[286]	[276,105,145,236]	-4	hSpCas9	negative selection	7025346
60646371	60646394	14	+	27260156	L33	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.11659847325388495	[185]	[214,56,97,174]	-3	hSpCas9	negative selection	7025347
60646503	60646526	14	+	27260156	L33	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.2067467563704508	[245]	[220,91,131,196]	-5	hSpCas9	negative selection	7089599
60649036	60649059	14	-	27260156	L33	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.4267470457978797	[424]	[230,160,200,322]	-7	hSpCas9	negative selection	7089600
60648860	60648883	14	-	27260156	L33	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.040714859750083154	[698]	[714,259,415,862]	0	hSpCas9	negative selection	7089601
60648754	60648777	14	+	27260156	K562	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.031858606344376206	[743]	[660,532,899,602]	0	hSpCas9	negative selection	7146596
60649155	60649178	14	+	27260156	K562	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.16131142656007824	[286]	[127,409,235,146]	-2	hSpCas9	negative selection	7146597
60646371	60646394	14	+	27260156	K562	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.6768200706500183	[185]	[243,368,329,130]	8	hSpCas9	negative selection	7146598
60646503	60646526	14	+	27260156	K562	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.4602321773421496	[245]	[174,241,188,46]	-5	hSpCas9	negative selection	7210850
60649036	60649059	14	-	27260156	K562	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.18654847305311453	[424]	[534,385,187,244]	-2	hSpCas9	negative selection	7210851
60648860	60648883	14	-	27260156	K562	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.037446561469903106	[698]	[511,804,514,587]	0	hSpCas9	negative selection	7210852
60648754	60648777	14	+	27260156	HT29	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.13577989469560248	[743]	[806,889,867,736]	-3	hSpCas9	negative selection	7267847
60649155	60649178	14	+	27260156	HT29	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.22075412060427246	[286]	[493,396,320,415]	4	hSpCas9	negative selection	7267848
60646371	60646394	14	+	27260156	HT29	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.12135619529343833	[185]	[186,324,159,170]	-2	hSpCas9	negative selection	7267849
60646503	60646526	14	+	27260156	HT29	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.13677842393435324	[245]	[343,192,313,237]	-3	hSpCas9	negative selection	7332101
60649036	60649059	14	-	27260156	HT29	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.350553075967337	[424]	[363,443,449,364]	-6	hSpCas9	negative selection	7332102
60648860	60648883	14	-	27260156	HT29	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.04729822096942826	[698]	[943,901,879,796]	0	hSpCas9	negative selection	7332103
60648754	60648777	14	+	27260156	MHHES1	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.050763821781104834	[743]	[615,919,843,821]	-1	hSpCas9	negative selection	7389098
60649155	60649178	14	+	27260156	MHHES1	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.27395358278349335	[286]	[576,190,546,270]	5	hSpCas9	negative selection	7389099
60646371	60646394	14	+	27260156	MHHES1	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.20073296721861844	[185]	[83,303,334,225]	3	hSpCas9	negative selection	7389100
60646503	60646526	14	+	27260156	MHHES1	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.6675889867036249	[245]	[210,245,155,107]	-8	hSpCas9	negative selection	7453352
60649036	60649059	14	-	27260156	MHHES1	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.15757229369996315	[424]	[268,455,664,325]	-3	hSpCas9	negative selection	7453353
60648860	60648883	14	-	27260156	MHHES1	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.04607171733019677	[698]	[810,884,937,483]	-1	hSpCas9	negative selection	7453354
60648754	60648777	14	+	27260156	MEWO	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.11735277481196194	[743]	[873,756,656]	2	hSpCas9	negative selection	7510349
60649155	60649178	14	+	27260156	MEWO	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.19877892218432913	[286]	[356,288,287]	4	hSpCas9	negative selection	7510350
60646371	60646394	14	+	27260156	MEWO	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.001044765112764967	[185]	[190,161,171]	0	hSpCas9	negative selection	7510351
60646503	60646526	14	+	27260156	MEWO	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.056154841360118835	[245]	[215,220,225]	-1	hSpCas9	negative selection	7574603
60649036	60649059	14	-	27260156	MEWO	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.7047797534711546	[424]	[311,239,192]	-8	hSpCas9	negative selection	7574604
60648860	60648883	14	-	27260156	MEWO	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.010742616959998674	[698]	[742,595,653]	0	hSpCas9	negative selection	7574605
60648754	60648777	14	+	27260156	LNCAPCLONEFGC	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.15068929026671896	[743]	[663,778,776,775]	2	hSpCas9	negative selection	7631600
60649155	60649178	14	+	27260156	LNCAPCLONEFGC	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.11972693566056836	[286]	[255,177,409,141]	-2	hSpCas9	negative selection	7631601
60646371	60646394	14	+	27260156	LNCAPCLONEFGC	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.13962639199417182	[185]	[117,185,194,245]	2	hSpCas9	negative selection	7631602
60646503	60646526	14	+	27260156	LNCAPCLONEFGC	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.1997945074998957	[245]	[255,163,242,120]	-3	hSpCas9	negative selection	7695854
60649036	60649059	14	-	27260156	LNCAPCLONEFGC	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.6898318181491472	[424]	[158,192,217,385]	-8	hSpCas9	negative selection	7695855
60648860	60648883	14	-	27260156	LNCAPCLONEFGC	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.06690601409465813	[698]	[596,610,694,758]	1	hSpCas9	negative selection	7695856
60648754	60648777	14	+	27260156	PANC0327	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.38279143920648606	[743]	[1057,795,1163,453]	5	hSpCas9	negative selection	7752851
60649155	60649178	14	+	27260156	PANC0327	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.10959377295924322	[286]	[228,234,374,105]	-2	hSpCas9	negative selection	7752852
60646371	60646394	14	+	27260156	PANC0327	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.19570833319855563	[185]	[266,45,241,44]	-3	hSpCas9	negative selection	7752853
60646503	60646526	14	+	27260156	PANC0327	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.13263057020657576	[245]	[400,204,117,88]	-2	hSpCas9	negative selection	7817105
60649036	60649059	14	-	27260156	PANC0327	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.004548819542867427	[424]	[245,361,659,228]	0	hSpCas9	negative selection	7817106
60648860	60648883	14	-	27260156	PANC0327	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.3098193139468486	[698]	[339,566,589,484]	-4	hSpCas9	negative selection	7817107
60648754	60648777	14	+	27260156	NCIH2009	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.0434079927072768	[743]	[1065,1043,924]	0	hSpCas9	negative selection	7874102
60649155	60649178	14	+	27260156	NCIH2009	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.6972425288818525	[286]	[931,488,586]	8	hSpCas9	negative selection	7874103
60646371	60646394	14	+	27260156	NCIH2009	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.554931307200319	[185]	[243,156,142]	-6	hSpCas9	negative selection	7874104
60646503	60646526	14	+	27260156	NCIH2009	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.07529812178635287	[245]	[324,263,389]	-1	hSpCas9	negative selection	7938356
60649036	60649059	14	-	27260156	NCIH2009	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.556962653862236	[424]	[483,461,278]	-6	hSpCas9	negative selection	7938357
60648860	60648883	14	-	27260156	NCIH2009	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.28064161954374356	[698]	[1284,1211,1078]	4	hSpCas9	negative selection	7938358
60648754	60648777	14	+	27260156	NCIH1373	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.34243977161987055	[743]	[733,388,808,193]	-3	hSpCas9	negative selection	7995353
60649155	60649178	14	+	27260156	NCIH1373	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.2592538423185295	[286]	[690,219,260,114]	2	hSpCas9	negative selection	7995354
60646371	60646394	14	+	27260156	NCIH1373	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.03902015183093566	[185]	[199,213,302,33]	0	hSpCas9	negative selection	7995355
60646503	60646526	14	+	27260156	NCIH1373	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.3232245774003901	[245]	[145,176,267,74]	-3	hSpCas9	negative selection	8059607
60649036	60649059	14	-	27260156	NCIH1373	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.30676260881462836	[424]	[354,370,528,70]	-3	hSpCas9	negative selection	8059608
60648860	60648883	14	-	27260156	NCIH1373	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.09845858658247197	[698]	[906,685,955,216]	1	hSpCas9	negative selection	8059609
60648754	60648777	14	+	27260156	PATU8902	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.33649395096393486	[743]	[1611,1293,1116,1236]	3	hSpCas9	negative selection	8116604
60649155	60649178	14	+	27260156	PATU8902	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.7259486002355764	[286]	[798,621,736,431]	7	hSpCas9	negative selection	8116605
60646371	60646394	14	+	27260156	PATU8902	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.4946372735609489	[185]	[422,637,136,311]	5	hSpCas9	negative selection	8116606
60646503	60646526	14	+	27260156	PATU8902	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.23937892655640147	[245]	[81,556,246,286]	-2	hSpCas9	negative selection	8180858
60649036	60649059	14	-	27260156	PATU8902	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.24363740996942831	[424]	[487,348,661,447]	-2	hSpCas9	negative selection	8180859
60648860	60648883	14	-	27260156	PATU8902	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.03890884146633389	[698]	[1029,1088,920,721]	0	hSpCas9	negative selection	8180860
60648754	60648777	14	+	27260156	PANC1	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.02807194730026874	[743]	[506,760,766,511]	0	hSpCas9	negative selection	8237855
60649155	60649178	14	+	27260156	PANC1	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.19459222765454087	[286]	[128,391,266,123]	-3	hSpCas9	negative selection	8237856
60646371	60646394	14	+	27260156	PANC1	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.1590798321717415	[185]	[156,168,127,123]	-3	hSpCas9	negative selection	8237857
60646503	60646526	14	+	27260156	PANC1	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.6158679092036266	[245]	[209,199,101,60]	-7	hSpCas9	negative selection	8302109
60649036	60649059	14	-	27260156	PANC1	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.7126643996076248	[424]	[186,246,281,183]	-7	hSpCas9	negative selection	8302110
60648860	60648883	14	-	27260156	PANC1	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.27097343054260853	[698]	[482,602,490,436]	-4	hSpCas9	negative selection	8302111
60648754	60648777	14	+	27260156	PANC0813	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.2626728143787357	[743]	[729,824,744,618]	-4	hSpCas9	negative selection	8359106
60649155	60649178	14	+	27260156	PANC0813	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.34738627547994655	[286]	[366,501,375,461]	5	hSpCas9	negative selection	8359107
60646371	60646394	14	+	27260156	PANC0813	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.40987823624381514	[185]	[265,69,183,147]	-6	hSpCas9	negative selection	8359108
60646503	60646526	14	+	27260156	PANC0813	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.015894648720156335	[245]	[304,161,390,286]	0	hSpCas9	negative selection	8423360
60649036	60649059	14	-	27260156	PANC0813	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.30426482651551967	[424]	[323,447,274,552]	-5	hSpCas9	negative selection	8423361
60648860	60648883	14	-	27260156	PANC0813	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.1947450505199818	[698]	[960,1005,836,953]	3	hSpCas9	negative selection	8423362
60648754	60648777	14	+	27260156	RDES	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.03319678558124817	[743]	[732,832,895,1079]	0	hSpCas9	negative selection	8480357
60649155	60649178	14	+	27260156	RDES	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.3564109543235887	[286]	[294,193,218,319]	-6	hSpCas9	negative selection	8480358
60646371	60646394	14	+	27260156	RDES	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.08747040972001097	[185]	[226,184,193,184]	-1	hSpCas9	negative selection	8480359
60646503	60646526	14	+	27260156	RDES	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.1202101124686652	[245]	[191,290,235,336]	-2	hSpCas9	negative selection	8544611
60649036	60649059	14	-	27260156	RDES	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.7094321751038026	[424]	[215,268,252,498]	-8	hSpCas9	negative selection	8544612
60648860	60648883	14	-	27260156	RDES	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.18680002135831913	[698]	[596,698,643,916]	-3	hSpCas9	negative selection	8544613
60648754	60648777	14	+	27260156	PC3	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.42109013986099253	[743]	[325,626,1021,462]	-7	hSpCas9	negative selection	8601608
60649155	60649178	14	+	27260156	PC3	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.2588044552284774	[286]	[202,253,273,221]	-5	hSpCas9	negative selection	8601609
60646371	60646394	14	+	27260156	PC3	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.7806883605618126	[185]	[261,157,695,299]	9	hSpCas9	negative selection	8601610
60646503	60646526	14	+	27260156	PC3	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.379379312040383	[245]	[64,106,559,216]	-7	hSpCas9	negative selection	8665862
60649036	60649059	14	-	27260156	PC3	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.7604461165084349	[424]	[240,258,264,205]	-9	hSpCas9	negative selection	8665863
60648860	60648883	14	-	27260156	PC3	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.007425160778454676	[698]	[539,728,831,707]	0	hSpCas9	negative selection	8665864
60648754	60648777	14	+	27260156	PATU8988T	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.21317773153010705	[743]	[503,638,697,641]	-4	hSpCas9	negative selection	8722859
60649155	60649178	14	+	27260156	PATU8988T	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.15610207400233433	[286]	[535,251,224,210]	2	hSpCas9	negative selection	8722860
60646371	60646394	14	+	27260156	PATU8988T	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.17172642854311682	[185]	[141,213,135,329]	3	hSpCas9	negative selection	8722861
60646503	60646526	14	+	27260156	PATU8988T	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	0.036315258704502806	[245]	[275,220,271,199]	0	hSpCas9	negative selection	8787113
60649036	60649059	14	-	27260156	PATU8988T	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.07143181283302599	[424]	[429,390,369,370]	-1	hSpCas9	negative selection	8787114
60648860	60648883	14	-	27260156	PATU8988T	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.0034655946613617594	[698]	[365,781,649,927]	0	hSpCas9	negative selection	8787115
60648754	60648777	14	+	27260156	T47D	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.10530771552949925	[743]	[797,813,741,870]	-2	hSpCas9	negative selection	8844110
60649155	60649178	14	+	27260156	T47D	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.07767354795542747	[286]	[277,319,314,354]	-2	hSpCas9	negative selection	8844111
60646371	60646394	14	+	27260156	T47D	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.24954213412055193	[185]	[182,148,183,216]	-5	hSpCas9	negative selection	8844112
60646503	60646526	14	+	27260156	T47D	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.520340001207418	[245]	[185,156,236,222]	-8	hSpCas9	negative selection	8908364
60649036	60649059	14	-	27260156	T47D	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.6413117479533531	[424]	[402,284,259,325]	-8	hSpCas9	negative selection	8908365
60648860	60648883	14	-	27260156	T47D	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.030394450904766224	[698]	[881,756,853,839]	0	hSpCas9	negative selection	8908366
60648754	60648777	14	+	27260156	SU8686	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.18847979632955258	[743]	[534,558,742,798]	-3	hSpCas9	negative selection	8965361
60649155	60649178	14	+	27260156	SU8686	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.10755057451169436	[286]	[197,258,286,329]	-2	hSpCas9	negative selection	8965362
60646371	60646394	14	+	27260156	SU8686	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.8415558337031994	[185]	[70,103,126,114]	-8	hSpCas9	negative selection	8965363
60646503	60646526	14	+	27260156	SU8686	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.3917271666455884	[245]	[164,158,230,195]	-6	hSpCas9	negative selection	9029615
60649036	60649059	14	-	27260156	SU8686	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.6368533649300819	[424]	[158,295,250,406]	-7	hSpCas9	negative selection	9029616
60648860	60648883	14	-	27260156	SU8686	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.05481293822587319	[698]	[765,808,653,607]	0	hSpCas9	negative selection	9029617
60648754	60648777	14	+	27260156	SKES1	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.25436238706063	[743]	[836,667,553,476]	-5	hSpCas9	negative selection	9086612
60649155	60649178	14	+	27260156	SKES1	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	-0.174873125937405	[286]	[328,254,213,227]	-4	hSpCas9	negative selection	9086613
60646371	60646394	14	+	27260156	SKES1	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	0.09103214175673213	[185]	[249,202,187,159]	2	hSpCas9	negative selection	9086614
60646503	60646526	14	+	27260156	SKES1	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.13346315163798073	[245]	[200,258,243,192]	-3	hSpCas9	negative selection	9150866
60649036	60649059	14	-	27260156	SKES1	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.9471265716147191	[424]	[222,189,232,226]	-9	hSpCas9	negative selection	9150867
60648860	60648883	14	-	27260156	SKES1	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.12978501930913788	[698]	[721,674,669,506]	-3	hSpCas9	negative selection	9150868
60648754	60648777	14	+	27260156	TOV112D	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.30034035309576984	[743]	[693,782,471,523]	-5	hSpCas9	negative selection	9207863
60649155	60649178	14	+	27260156	TOV112D	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.49257554571611245	[286]	[586,487,319,261]	8	hSpCas9	negative selection	9207864
60646371	60646394	14	+	27260156	TOV112D	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.3294810756349822	[185]	[153,211,96,145]	-6	hSpCas9	negative selection	9207865
60646503	60646526	14	+	27260156	TOV112D	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.20313247511384414	[245]	[160,337,212,170]	-4	hSpCas9	negative selection	9272117
60649036	60649059	14	-	27260156	TOV112D	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.6395620538874104	[424]	[295,282,287,230]	-8	hSpCas9	negative selection	9272118
60648860	60648883	14	-	27260156	TOV112D	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.3199160015154362	[698]	[1142,831,713,818]	6	hSpCas9	negative selection	9272119
60648754	60648777	14	+	27260156	TC71	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.23785412458659255	[743]	[561,711,616,827]	-6	hSpCas9	negative selection	9329114
60649155	60649178	14	+	27260156	TC71	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.06967877514910414	[286]	[326,334,275,356]	1	hSpCas9	negative selection	9329115
60646371	60646394	14	+	27260156	TC71	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.05662391323924054	[185]	[191,216,182,173]	-1	hSpCas9	negative selection	9329116
60646503	60646526	14	+	27260156	TC71	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.20925900167055866	[245]	[251,202,176,284]	-5	hSpCas9	negative selection	9393368
60649036	60649059	14	-	27260156	TC71	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.6923455863358401	[424]	[237,324,269,296]	-9	hSpCas9	negative selection	9393369
60648860	60648883	14	-	27260156	TC71	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	0.12290973022562812	[698]	[650,982,779,856]	3	hSpCas9	negative selection	9393370
60648754	60648777	14	+	27260156	TC32	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.1286294834754158	[743]	[805,435,935,997]	2	hSpCas9	negative selection	9450365
60649155	60649178	14	+	27260156	TC32	viability	TCCTGCGTAAAGCCAAACGACGG	SIX1	ENSG00000126778	0.14381575362292698	[286]	[144,397,370,248]	2	hSpCas9	negative selection	9450366
60646371	60646394	14	+	27260156	TC32	viability	GGCTGCGAGGCTGTTAAGCCCGG	SIX1	ENSG00000126778	-0.30141628769491735	[185]	[138,108,206,126]	-5	hSpCas9	negative selection	9450367
60646503	60646526	14	+	27260156	TC32	viability	AGCGGCTTGCCCCCTTCCAGAGG	SIX1	ENSG00000126778	-0.3242612553516442	[245]	[140,139,237,243]	-5	hSpCas9	negative selection	9514619
60649036	60649059	14	-	27260156	TC32	viability	CAAGAACGAGAGCGTACTCAAGG	SIX1	ENSG00000126778	-0.7959189109672545	[424]	[230,139,273,307]	-9	hSpCas9	negative selection	9514620
60648860	60648883	14	-	27260156	TC32	viability	TGGGCGCCGTGGGCAAATATCGG	SIX1	ENSG00000126778	-0.19174520627226155	[698]	[511,498,607,694]	-3	hSpCas9	negative selection	9514621
60646399	60646422	14	+	27869803	HPAFII	viability after 27 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-0.6164989899048792	[271]	[89,95,NaN]	-4	hSpCas9	negative selection	9551948
60646423	60646446	14	+	27869803	HPAFII	viability after 27 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	-0.503506538567632	[251]	[87,97,NaN]	-4	hSpCas9	negative selection	9551949
60646512	60646535	14	-	27869803	HPAFII	viability after 27 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-1.4310789832076112	[310]	[16,96,NaN]	-7	hSpCas9	negative selection	9551950
60648723	60648746	14	+	27869803	HPAFII	viability after 27 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.7989864122154664	[225]	[371,68,NaN]	6	hSpCas9	negative selection	9551951
60649045	60649068	14	+	27869803	HPAFII	viability after 27 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	-0.2552945771355379	[322]	[240,59,NaN]	-2	hSpCas9	negative selection	9551952
60649169	60649192	14	+	27869803	HPAFII	viability after 27 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.12403589181646713	[387]	[232,148,NaN]	-1	hSpCas9	negative selection	9551953
60646399	60646422	14	+	27869803	HPAFII	viability after 15 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-0.3127958261909107	[271]	[370,150,NaN]	-4	hSpCas9	negative selection	9634397
60646423	60646446	14	+	27869803	HPAFII	viability after 15 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	-0.17654246818556163	[251]	[111,318,NaN]	-2	hSpCas9	negative selection	9634398
60646512	60646535	14	-	27869803	HPAFII	viability after 15 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.6180464216213768	[310]	[136,267,NaN]	-6	hSpCas9	negative selection	9634399
60648723	60648746	14	+	27869803	HPAFII	viability after 15 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.06004880145511826	[225]	[378,174,NaN]	0	hSpCas9	negative selection	9634400
60649045	60649068	14	+	27869803	HPAFII	viability after 15 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	-0.16061968224083653	[322]	[452,221,NaN]	-2	hSpCas9	negative selection	9634401
60649169	60649192	14	+	27869803	HPAFII	viability after 15 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.2446075822351016	[387]	[486,267,NaN]	-3	hSpCas9	negative selection	9634402
60646399	60646422	14	+	27869803	ASPC1	viability after 36 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	0.3015018411626087	[600]	[366,290,153]	3	hSpCas9	negative selection	9716846
60646423	60646446	14	+	27869803	ASPC1	viability after 36 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	-0.5626573580910338	[630]	[268,87,111]	-5	hSpCas9	negative selection	9716847
60646512	60646535	14	-	27869803	ASPC1	viability after 36 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.33227535000247255	[720]	[139,336,130]	-3	hSpCas9	negative selection	9716848
60648723	60648746	14	+	27869803	ASPC1	viability after 36 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	1.1170763462411903	[571]	[714,195,418]	9	hSpCas9	negative selection	9716849
60649045	60649068	14	+	27869803	ASPC1	viability after 36 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.30894850647268157	[1122]	[577,483,416]	3	hSpCas9	negative selection	9716850
60649169	60649192	14	+	27869803	ASPC1	viability after 36 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.43357848988729697	[1027]	[331,240,235]	-4	hSpCas9	negative selection	9716851
60646399	60646422	14	+	27869803	PATU8988S	viability after 35 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	0.5560672848779189	[687]	[361,452,NaN]	6	hSpCas9	negative selection	9799295
60646423	60646446	14	+	27869803	PATU8988S	viability after 35 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	-0.5298620959815366	[644]	[146,212,NaN]	-5	hSpCas9	negative selection	9799296
60646512	60646535	14	-	27869803	PATU8988S	viability after 35 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-0.5955868796956013	[744]	[226,169,NaN]	-6	hSpCas9	negative selection	9799297
60648723	60648746	14	+	27869803	PATU8988S	viability after 35 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.7158912216711518	[497]	[300,357,NaN]	7	hSpCas9	negative selection	9799298
60649045	60649068	14	+	27869803	PATU8988S	viability after 35 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.16674658794502384	[898]	[377,434,NaN]	2	hSpCas9	negative selection	9799299
60649169	60649192	14	+	27869803	PATU8988S	viability after 35 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	0.4355913207648292	[667]	[522,203,NaN]	5	hSpCas9	negative selection	9799300
60646399	60646422	14	+	27869803	PATU8988S	viability after 31 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	0.6996566142960412	[687]	[412,486,NaN]	7	hSpCas9	negative selection	9881744
60646423	60646446	14	+	27869803	PATU8988S	viability after 31 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	-0.20904868767425677	[644]	[108,366,NaN]	-2	hSpCas9	negative selection	9881745
60646512	60646535	14	-	27869803	PATU8988S	viability after 31 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-1.1149267814182773	[744]	[130,144,NaN]	-8	hSpCas9	negative selection	9881746
60648723	60648746	14	+	27869803	PATU8988S	viability after 31 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.5109038497012158	[497]	[267,301,NaN]	6	hSpCas9	negative selection	9881747
60649045	60649068	14	+	27869803	PATU8988S	viability after 31 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	0.05463541672955963	[898]	[304,457,NaN]	0	hSpCas9	negative selection	9881748
60649169	60649192	14	+	27869803	PATU8988S	viability after 31 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.35420459942335675	[667]	[276,120,NaN]	-4	hSpCas9	negative selection	9881749
60646399	60646422	14	+	27869803	HPAFII	viability after 35 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-0.8538497772079854	[271]	[102,45,NaN]	-5	hSpCas9	negative selection	9964193
60646423	60646446	14	+	27869803	HPAFII	viability after 35 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	-0.367967508129219	[251]	[40,163,NaN]	-2	hSpCas9	negative selection	9964194
60646512	60646535	14	-	27869803	HPAFII	viability after 35 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-1.036940329225471	[310]	[8,152,NaN]	-5	hSpCas9	negative selection	9964195
60648723	60648746	14	+	27869803	HPAFII	viability after 35 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.8533565845616184	[225]	[328,68,NaN]	5	hSpCas9	negative selection	9964196
60649045	60649068	14	+	27869803	HPAFII	viability after 35 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	-0.028632056660444827	[322]	[180,136,NaN]	0	hSpCas9	negative selection	9964197
60649169	60649192	14	+	27869803	HPAFII	viability after 35 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.009792318163523439	[387]	[267,112,NaN]	0	hSpCas9	negative selection	9964198
60646399	60646422	14	+	27869803	HPAFII	viability after 31 days	AATAGTTTGAGCTCCTGGCGTGG	SIX1	ENSG00000126778	-0.3477163862259771	[271]	[118,120,NaN]	-2	hSpCas9	negative selection	10046642
60646423	60646446	14	+	27869803	HPAFII	viability after 31 days	CCATATTGCCCTGCAGCAGAAGG	SIX1	ENSG00000126778	-1.206429808382717	[251]	[22,102,NaN]	-6	hSpCas9	negative selection	10046643
60646512	60646535	14	-	27869803	HPAFII	viability after 31 days	CAACTCTCTCCTCTGGAAGGGGG	SIX1	ENSG00000126778	-1.351776496680545	[310]	[9,131,NaN]	-7	hSpCas9	negative selection	10046644
60648723	60648746	14	+	27869803	HPAFII	viability after 31 days	TCCCGCTTCTCACGCGGCGATGG	SIX1	ENSG00000126778	0.7165520410448921	[225]	[362,39,NaN]	5	hSpCas9	negative selection	10046645
60649045	60649068	14	+	27869803	HPAFII	viability after 31 days	CGCTCTCGTTCTTGTGCAGGTGG	SIX1	ENSG00000126778	-0.0602606243625427	[322]	[259,79,NaN]	0	hSpCas9	negative selection	10046646
60649169	60649192	14	+	27869803	HPAFII	viability after 31 days	AAACGACGGCAGCATCGACATGG	SIX1	ENSG00000126778	-0.32567247490100026	[387]	[223,118,NaN]	-2	hSpCas9	negative selection	10046647
60649027	60649050	14	-	28162770	P31FUJ	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.21504143994770683	[249]	[340]	2	hSpCas9	negative selection	10234556
60648782	60648805	14	-	28162770	P31FUJ	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	0.41780833854229116	[178]	[280]	4	hSpCas9	negative selection	10234557
60649008	60649031	14	-	28162770	P31FUJ	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.122243632188158	[266]	[682]	9	hSpCas9	negative selection	10234558
60648931	60648954	14	+	28162770	P31FUJ	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	0.5793062476138602	[302]	[531]	6	hSpCas9	negative selection	10234559
60648907	60648930	14	-	28162770	P31FUJ	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.304778787835851	[422]	[613]	3	hSpCas9	negative selection	10234560
60648854	60648877	14	+	28162770	P31FUJ	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.2021348523021702	[485]	[656]	2	hSpCas9	negative selection	10234561
60648754	60648777	14	+	28162770	P31FUJ	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.48796503264713464	[411]	[678]	5	hSpCas9	negative selection	10234562
60648643	60648666	14	-	28162770	P31FUJ	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	1.0891258904729837	[161]	[404]	9	hSpCas9	negative selection	10234563
60649156	60649179	14	-	28162770	P31FUJ	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	0.38636450465137107	[652]	[1002]	4	hSpCas9	negative selection	10234564
60649116	60649139	14	-	28162770	P31FUJ	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.37488037280686104	[104]	[159]	4	hSpCas9	negative selection	10234565
60649027	60649050	14	-	28162770	TF1	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	NaN	[NaN]	[323]	1	hSpCas9	negative selection	10403922
60648782	60648805	14	-	28162770	TF1	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	NaN	[NaN]	[173]	1	hSpCas9	negative selection	10403923
60649008	60649031	14	-	28162770	TF1	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	NaN	[NaN]	[402]	1	hSpCas9	negative selection	10403924
60648931	60648954	14	+	28162770	TF1	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	NaN	[NaN]	[176]	1	hSpCas9	negative selection	10403925
60648907	60648930	14	-	28162770	TF1	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	NaN	[NaN]	[421]	1	hSpCas9	negative selection	10403926
60648854	60648877	14	+	28162770	TF1	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	NaN	[NaN]	[638]	1	hSpCas9	negative selection	10403927
60648754	60648777	14	+	28162770	TF1	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	NaN	[NaN]	[260]	1	hSpCas9	negative selection	10403928
60648643	60648666	14	-	28162770	TF1	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10403929
60649156	60649179	14	-	28162770	TF1	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	NaN	[NaN]	[938]	1	hSpCas9	negative selection	10403930
60649116	60649139	14	-	28162770	TF1	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10403931
60649027	60649050	14	-	28162770	SKM1	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.6569701070109368	[79]	[222]	6	hSpCas9	negative selection	10573288
60648782	60648805	14	-	28162770	SKM1	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	1.5472321116437135	[29]	[154]	9	hSpCas9	negative selection	10573289
60649008	60649031	14	-	28162770	SKM1	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.2044705133391855	[53]	[219]	9	hSpCas9	negative selection	10573290
60648931	60648954	14	+	28162770	SKM1	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	0.08178298671869133	[92]	[173]	0	hSpCas9	negative selection	10573291
60648907	60648930	14	-	28162770	SKM1	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.1990599175058243	[135]	[275]	2	hSpCas9	negative selection	10573292
60648854	60648877	14	+	28162770	SKM1	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.41105764836629843	[153]	[361]	4	hSpCas9	negative selection	10573293
60648754	60648777	14	+	28162770	SKM1	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.34792330342030686	[79]	[179]	3	hSpCas9	negative selection	10573294
60648643	60648666	14	-	28162770	SKM1	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	0.559868937321639	[32]	[85]	5	hSpCas9	negative selection	10573295
60649156	60649179	14	-	28162770	SKM1	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	1.021112987153198	[147]	[530]	8	hSpCas9	negative selection	10573296
60649116	60649139	14	-	28162770	SKM1	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.7140512022182043	[19]	[57]	7	hSpCas9	negative selection	10573297
60649027	60649050	14	-	28162770	SKM1	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.6569701070109368	[79]	[222]	6	hSpCas9	negative selection	10742654
60648782	60648805	14	-	28162770	SKM1	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	1.5472321116437135	[29]	[154]	9	hSpCas9	negative selection	10742655
60649008	60649031	14	-	28162770	SKM1	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.2044705133391855	[53]	[219]	9	hSpCas9	negative selection	10742656
60648931	60648954	14	+	28162770	SKM1	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	0.08178298671869133	[92]	[173]	0	hSpCas9	negative selection	10742657
60648907	60648930	14	-	28162770	SKM1	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.1990599175058243	[135]	[275]	2	hSpCas9	negative selection	10742658
60648854	60648877	14	+	28162770	SKM1	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.41105764836629843	[153]	[361]	4	hSpCas9	negative selection	10742659
60648754	60648777	14	+	28162770	SKM1	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.34792330342030686	[79]	[179]	3	hSpCas9	negative selection	10742660
60648643	60648666	14	-	28162770	SKM1	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	0.559868937321639	[32]	[85]	5	hSpCas9	negative selection	10742661
60649156	60649179	14	-	28162770	SKM1	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	1.021112987153198	[147]	[530]	8	hSpCas9	negative selection	10742662
60649116	60649139	14	-	28162770	SKM1	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.7140512022182043	[19]	[57]	7	hSpCas9	negative selection	10742663
60649027	60649050	14	-	28162770	PL21	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.2950880185445828	[293]	[156]	2	hSpCas9	negative selection	10912020
60648782	60648805	14	-	28162770	PL21	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	-0.909484876685178	[81]	[18]	-6	hSpCas9	negative selection	10912021
60649008	60649031	14	-	28162770	PL21	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.35411091429815	[292]	[325]	9	hSpCas9	negative selection	10912022
60648931	60648954	14	+	28162770	PL21	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	-0.16684575538338198	[373]	[144]	-1	hSpCas9	negative selection	10912023
60648907	60648930	14	-	28162770	PL21	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.0995356735509143	[385]	[179]	0	hSpCas9	negative selection	10912024
60648854	60648877	14	+	28162770	PL21	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.6743006960643334	[752]	[522]	6	hSpCas9	negative selection	10912025
60648754	60648777	14	+	28162770	PL21	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.4356276934374512	[281]	[165]	4	hSpCas9	negative selection	10912026
60648643	60648666	14	-	28162770	PL21	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	0.39758567869553707	[74]	[42]	3	hSpCas9	negative selection	10912027
60649156	60649179	14	-	28162770	PL21	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	0.4040119478549704	[447]	[257]	3	hSpCas9	negative selection	10912028
60649116	60649139	14	-	28162770	PL21	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.8297711645442047	[52]	[40]	7	hSpCas9	negative selection	10912029
60649027	60649050	14	-	28162770	P31FUJ	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.21504143994770683	[249]	[340]	2	hSpCas9	negative selection	11081386
60648782	60648805	14	-	28162770	P31FUJ	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	0.41780833854229116	[178]	[280]	4	hSpCas9	negative selection	11081387
60649008	60649031	14	-	28162770	P31FUJ	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.122243632188158	[266]	[682]	9	hSpCas9	negative selection	11081388
60648931	60648954	14	+	28162770	P31FUJ	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	0.5793062476138602	[302]	[531]	6	hSpCas9	negative selection	11081389
60648907	60648930	14	-	28162770	P31FUJ	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.304778787835851	[422]	[613]	3	hSpCas9	negative selection	11081390
60648854	60648877	14	+	28162770	P31FUJ	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.2021348523021702	[485]	[656]	2	hSpCas9	negative selection	11081391
60648754	60648777	14	+	28162770	P31FUJ	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.48796503264713464	[411]	[678]	5	hSpCas9	negative selection	11081392
60648643	60648666	14	-	28162770	P31FUJ	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	1.0891258904729837	[161]	[404]	9	hSpCas9	negative selection	11081393
60649156	60649179	14	-	28162770	P31FUJ	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	0.38636450465137107	[652]	[1002]	4	hSpCas9	negative selection	11081394
60649116	60649139	14	-	28162770	P31FUJ	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.37488037280686104	[104]	[159]	4	hSpCas9	negative selection	11081395
60649027	60649050	14	-	28162770	OCIAML5	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.5729550169874691	[107]	[289]	5	hSpCas9	negative selection	11250752
60648782	60648805	14	-	28162770	OCIAML5	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	0.29176920170965426	[61]	[136]	2	hSpCas9	negative selection	11250753
60649008	60649031	14	-	28162770	OCIAML5	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.738857488095876	[160]	[484]	6	hSpCas9	negative selection	11250754
60648931	60648954	14	+	28162770	OCIAML5	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	-0.21069754871380197	[208]	[325]	-1	hSpCas9	negative selection	11250755
60648907	60648930	14	-	28162770	OCIAML5	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.10017443245968793	[249]	[420]	0	hSpCas9	negative selection	11250756
60648854	60648877	14	+	28162770	OCIAML5	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.676377606572762	[294]	[850]	6	hSpCas9	negative selection	11250757
60648754	60648777	14	+	28162770	OCIAML5	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.14793342913600327	[239]	[479]	1	hSpCas9	negative selection	11250758
60648643	60648666	14	-	28162770	OCIAML5	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	0.7411635458407595	[57]	[174]	6	hSpCas9	negative selection	11250759
60649156	60649179	14	-	28162770	OCIAML5	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	0.5764451628315372	[372]	[1003]	5	hSpCas9	negative selection	11250760
60649116	60649139	14	-	28162770	OCIAML5	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.7458349855646574	[36]	[111]	6	hSpCas9	negative selection	11250761
60649027	60649050	14	-	28162770	EOL1	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.9763091992602762	[437]	[453]	8	hSpCas9	negative selection	11420118
60648782	60648805	14	-	28162770	EOL1	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	1.169170140290448	[91]	[108]	8	hSpCas9	negative selection	11420119
60649008	60649031	14	-	28162770	EOL1	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.5022054716684572	[527]	[393]	4	hSpCas9	negative selection	11420120
60648931	60648954	14	+	28162770	EOL1	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	1.1106440636839925	[551]	[627]	8	hSpCas9	negative selection	11420121
60648907	60648930	14	-	28162770	EOL1	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.35744479196714374	[765]	[314]	-3	hSpCas9	negative selection	11420122
60648854	60648877	14	+	28162770	EOL1	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.5451016306062286	[1080]	[830]	5	hSpCas9	negative selection	11420123
60648754	60648777	14	+	28162770	EOL1	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.15402961769330192	[463]	[271]	1	hSpCas9	negative selection	11420124
60648643	60648666	14	-	28162770	EOL1	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	-0.13130546316298297	[157]	[75]	-1	hSpCas9	negative selection	11420125
60649156	60649179	14	-	28162770	EOL1	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	0.3133753915265296	[610]	[399]	3	hSpCas9	negative selection	11420126
60649116	60649139	14	-	28162770	EOL1	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	-2.0754522284294654	[151]	[18]	-8	hSpCas9	negative selection	11420127
60649027	60649050	14	-	28162770	MOLM13	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.66476592915498	[382]	[438]	5	hSpCas9	negative selection	11589484
60648782	60648805	14	-	28162770	MOLM13	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	0.26435598745944655	[113]	[98]	2	hSpCas9	negative selection	11589485
60649008	60649031	14	-	28162770	MOLM13	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.5986513274154586	[389]	[853]	9	hSpCas9	negative selection	11589486
60648931	60648954	14	+	28162770	MOLM13	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	0.611837897258171	[466]	[515]	4	hSpCas9	negative selection	11589487
60648907	60648930	14	-	28162770	MOLM13	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.7291708162746215	[548]	[657]	5	hSpCas9	negative selection	11589488
60648854	60648877	14	+	28162770	MOLM13	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.5611007828282435	[883]	[942]	4	hSpCas9	negative selection	11589489
60648754	60648777	14	+	28162770	MOLM13	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.7762365617391505	[378]	[159]	-4	hSpCas9	negative selection	11589490
60648643	60648666	14	-	28162770	MOLM13	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	-1.450496852901769	[188]	[49]	-6	hSpCas9	negative selection	11589491
60649156	60649179	14	-	28162770	MOLM13	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	0.6175823143024277	[749]	[831]	4	hSpCas9	negative selection	11589492
60649116	60649139	14	-	28162770	MOLM13	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	-0.03461095898460442	[84]	[59]	0	hSpCas9	negative selection	11589493
60649027	60649050	14	-	28162770	HEL	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	1.0417015684211295	[360]	[475]	8	hSpCas9	negative selection	11758850
60648782	60648805	14	-	28162770	HEL	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	0.701037472565024	[96]	[100]	6	hSpCas9	negative selection	11758851
60649008	60649031	14	-	28162770	HEL	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.8651312533368046	[347]	[405]	7	hSpCas9	negative selection	11758852
60648931	60648954	14	+	28162770	HEL	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	0.07149461252698086	[470]	[316]	0	hSpCas9	negative selection	11758853
60648907	60648930	14	-	28162770	HEL	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.593565990018655	[566]	[547]	5	hSpCas9	negative selection	11758854
60648854	60648877	14	+	28162770	HEL	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.34718418448024724	[663]	[540]	3	hSpCas9	negative selection	11758855
60648754	60648777	14	+	28162770	HEL	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.22900399198914934	[368]	[276]	1	hSpCas9	negative selection	11758856
60648643	60648666	14	-	28162770	HEL	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	0.7691871672412962	[130]	[142]	6	hSpCas9	negative selection	11758857
60649156	60649179	14	-	28162770	HEL	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	-0.02386893382229327	[726]	[457]	0	hSpCas9	negative selection	11758858
60649116	60649139	14	-	28162770	HEL	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	-0.5648565874080103	[96]	[41]	-4	hSpCas9	negative selection	11758859
60649027	60649050	14	-	28162770	MV411	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.4923514260484845	[226]	[268]	4	hSpCas9	negative selection	11928216
60648782	60648805	14	-	28162770	MV411	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	-0.21723071622066903	[68]	[49]	-2	hSpCas9	negative selection	11928217
60649008	60649031	14	-	28162770	MV411	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.205002284462379	[206]	[401]	9	hSpCas9	negative selection	11928218
60648931	60648954	14	+	28162770	MV411	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	0.47933344480766504	[280]	[329]	4	hSpCas9	negative selection	11928219
60648907	60648930	14	-	28162770	MV411	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.10614355474056536	[342]	[310]	0	hSpCas9	negative selection	11928220
60648854	60648877	14	+	28162770	MV411	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.18977221007151668	[586]	[563]	1	hSpCas9	negative selection	11928221
60648754	60648777	14	+	28162770	MV411	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.8487634977128187	[262]	[398]	7	hSpCas9	negative selection	11928222
60648643	60648666	14	-	28162770	MV411	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	-0.4938281808170566	[111]	[66]	-4	hSpCas9	negative selection	11928223
60649156	60649179	14	-	28162770	MV411	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	0.7563666149715211	[460]	[655]	6	hSpCas9	negative selection	11928224
60649116	60649139	14	-	28162770	MV411	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	1.8239384727557355	[56]	[169]	9	hSpCas9	negative selection	11928225
60649027	60649050	14	-	28162770	MONOMAC1	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	-0.18881634025458527	[174]	[175]	-2	hSpCas9	negative selection	12097582
60648782	60648805	14	-	28162770	MONOMAC1	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	1.0253555742768943	[53]	[125]	8	hSpCas9	negative selection	12097583
60649008	60649031	14	-	28162770	MONOMAC1	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.43224798464689707	[202]	[313]	4	hSpCas9	negative selection	12097584
60648931	60648954	14	+	28162770	MONOMAC1	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	-0.32317787719263785	[214]	[196]	-3	hSpCas9	negative selection	12097585
60648907	60648930	14	-	28162770	MONOMAC1	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	-0.02015908497547403	[321]	[363]	0	hSpCas9	negative selection	12097586
60648854	60648877	14	+	28162770	MONOMAC1	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.5115469457368305	[461]	[754]	5	hSpCas9	negative selection	12097587
60648754	60648777	14	+	28162770	MONOMAC1	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.7186649186337862	[184]	[348]	7	hSpCas9	negative selection	12097588
60648643	60648666	14	-	28162770	MONOMAC1	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	0.324500273519969	[61]	[88]	3	hSpCas9	negative selection	12097589
60649156	60649179	14	-	28162770	MONOMAC1	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	1.2039058223335035	[269]	[712]	9	hSpCas9	negative selection	12097590
60649116	60649139	14	-	28162770	MONOMAC1	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	-1.5073769676717041	[61]	[24]	-8	hSpCas9	negative selection	12097591
60649027	60649050	14	-	28162770	OCIAML2	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.46899755677835686	[60]	[467]	4	hSpCas9	negative selection	12266948
60648782	60648805	14	-	28162770	OCIAML2	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	1.6337068345725743	[9]	[171]	9	hSpCas9	negative selection	12266949
60649008	60649031	14	-	28162770	OCIAML2	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	0.8296497063404378	[46]	[462]	7	hSpCas9	negative selection	12266950
60648931	60648954	14	+	28162770	OCIAML2	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	0.34315136597487605	[63]	[449]	3	hSpCas9	negative selection	12266951
60648907	60648930	14	-	28162770	OCIAML2	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.08249658835699014	[83]	[492]	0	hSpCas9	negative selection	12266952
60648854	60648877	14	+	28162770	OCIAML2	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	-0.10649517023410948	[127]	[658]	-1	hSpCas9	negative selection	12266953
60648754	60648777	14	+	28162770	OCIAML2	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	-0.1657752437137403	[67]	[335]	-1	hSpCas9	negative selection	12266954
60648643	60648666	14	-	28162770	OCIAML2	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	0.6131385324504366	[22]	[194]	6	hSpCas9	negative selection	12266955
60649156	60649179	14	-	28162770	OCIAML2	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	0.8991450288855107	[85]	[888]	8	hSpCas9	negative selection	12266956
60649116	60649139	14	-	28162770	OCIAML2	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	0.2039698879636711	[12]	[82]	2	hSpCas9	negative selection	12266957
60649027	60649050	14	-	28162770	OCIAML3	viability	GAGCGTACTCAAGGCCAAGGCGG	SIX1	ENSG00000126778	0.10499010364302264	[76]	[249]	1	hSpCas9	negative selection	12436314
60648782	60648805	14	-	28162770	OCIAML3	viability	ACTGCTTCAAGGAGAAGTCGAGG	SIX1	ENSG00000126778	0.3793572331723702	[40]	[160]	3	hSpCas9	negative selection	12436315
60649008	60649031	14	-	28162770	OCIAML3	viability	GCGGTGGTCGCCTTCCACCGCGG	SIX1	ENSG00000126778	1.1335182579557377	[68]	[456]	8	hSpCas9	negative selection	12436316
60648931	60648954	14	+	28162770	OCIAML3	viability	ACAGTTGCTGCAGTTTGGGGTGG	SIX1	ENSG00000126778	0.42034765265290674	[99]	[403]	4	hSpCas9	negative selection	12436317
60648907	60648930	14	-	28162770	OCIAML3	viability	GCTGAAGGCGCATTACGTGGAGG	SIX1	ENSG00000126778	0.8051112585266449	[130]	[690]	7	hSpCas9	negative selection	12436318
60648854	60648877	14	+	28162770	OCIAML3	viability	GCGCACCCGATATTTGCCCACGG	SIX1	ENSG00000126778	0.3460498192195547	[128]	[494]	3	hSpCas9	negative selection	12436319
60648754	60648777	14	+	28162770	OCIAML3	viability	TGTGCGCGTACCACTCCCGCAGG	SIX1	ENSG00000126778	0.39067156039208106	[70]	[280]	3	hSpCas9	negative selection	12436320
60648643	60648666	14	-	28162770	OCIAML3	viability	GAGGCAAAGAGACCGGGCCGCGG	SIX1	ENSG00000126778	0.15731324681911307	[29]	[100]	1	hSpCas9	negative selection	12436321
60649156	60649179	14	-	28162770	OCIAML3	viability	GCCGTCGTTTGGCTTTACGCAGG	SIX1	ENSG00000126778	1.2539892662307868	[114]	[827]	9	hSpCas9	negative selection	12436322
60649116	60649139	14	-	28162770	OCIAML3	viability	TGCGAGGTTCTGCAGCAAGGCGG	SIX1	ENSG00000126778	-0.6200028488571075	[27]	[54]	-5	hSpCas9	negative selection	12436323