Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10736
• Symbol:SIX2
• Description:SIX homeobox 2

DataSource: http://genomecrispr.dkfz.de/#!/results/SIX2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
45009090	45009113	2	+	26472758	Jiyoye	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.08233569119860795	[371]	[296]	0	hSpCas9	negative selection	147131
45008598	45008621	2	+	26472758	Jiyoye	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	-0.38889373300521574	[190]	[109]	-3	hSpCas9	negative selection	147132
45008825	45008848	2	-	26472758	Jiyoye	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.3320180219371339	[196]	[186]	2	hSpCas9	negative selection	147133
45009037	45009060	2	-	26472758	Jiyoye	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	0.17500193937684017	[73]	[62]	1	hSpCas9	negative selection	147134
45008976	45008999	2	+	26472758	Jiyoye	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.07702677981354267	[43]	[34]	0	hSpCas9	negative selection	147135
45008942	45008965	2	-	26472758	Jiyoye	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.47993172394118755	[115]	[121]	3	hSpCas9	negative selection	147136
45008929	45008952	2	-	26472758	Jiyoye	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.9332441931734612	[49]	[71]	6	hSpCas9	negative selection	147137
45008852	45008875	2	+	26472758	Jiyoye	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	1.0394435970053864	[79]	[123]	7	hSpCas9	negative selection	147138
45008775	45008798	2	+	26472758	Jiyoye	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	6.655102894949459	[0]	[75]	9	hSpCas9	negative selection	147139
45008633	45008656	2	-	26472758	Jiyoye	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	-0.14363889680343728	[166]	[113]	-1	hSpCas9	negative selection	147140
45009090	45009113	2	+	26472758	KBM7	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.05190131642831819	[1677,1259]	[754,667]	0	hSpCas9	negative selection	338249
45008598	45008621	2	+	26472758	KBM7	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	-0.2949241275983454	[916,729]	[209,405]	-3	hSpCas9	negative selection	338250
45008825	45008848	2	-	26472758	KBM7	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.32791819128761035	[1104,883]	[646,525]	3	hSpCas9	negative selection	338251
45009037	45009060	2	-	26472758	KBM7	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-0.028202457263290893	[646,345]	[223,221]	0	hSpCas9	negative selection	338252
45008976	45008999	2	+	26472758	KBM7	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	-0.03366786657923715	[218,197]	[109,82]	0	hSpCas9	negative selection	338253
45008942	45008965	2	-	26472758	KBM7	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.35630882483086557	[483,511]	[262,336]	4	hSpCas9	negative selection	338254
45008929	45008952	2	-	26472758	KBM7	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.29235261351400466	[299,203]	[114,167]	3	hSpCas9	negative selection	338255
45008852	45008875	2	+	26472758	KBM7	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	-0.11139071720047322	[429,456]	[145,237]	-1	hSpCas9	negative selection	338256
45008775	45008798	2	+	26472758	KBM7	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	0.5067842572956199	[201,157]	[112,124]	5	hSpCas9	negative selection	338257
45008633	45008656	2	-	26472758	KBM7	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.8255025461095256	[435,414]	[319,386]	8	hSpCas9	negative selection	338258
45009090	45009113	2	+	26472758	Raji	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	-0.06254146606871269	[584]	[129]	0	hSpCas9	negative selection	529367
45008598	45008621	2	+	26472758	Raji	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	-0.27304020882390734	[452]	[86]	-2	hSpCas9	negative selection	529368
45008825	45008848	2	-	26472758	Raji	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.6255689962859832	[358]	[53]	-5	hSpCas9	negative selection	529369
45009037	45009060	2	-	26472758	Raji	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	0.210477028337703	[215]	[57]	2	hSpCas9	negative selection	529370
45008976	45008999	2	+	26472758	Raji	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	-0.8761283418378314	[86]	[10]	-6	hSpCas9	negative selection	529371
45008942	45008965	2	-	26472758	Raji	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.13337874390654386	[219]	[55]	1	hSpCas9	negative selection	529372
45008929	45008952	2	-	26472758	Raji	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.7052850918022536	[147]	[55]	6	hSpCas9	negative selection	529373
45008852	45008875	2	+	26472758	Raji	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	0.19693512035189184	[202]	[53]	1	hSpCas9	negative selection	529374
45008775	45008798	2	+	26472758	Raji	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	-0.09192527284980734	[123]	[26]	-1	hSpCas9	negative selection	529375
45008633	45008656	2	-	26472758	Raji	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.15318722498672407	[216]	[55]	1	hSpCas9	negative selection	529376
45009090	45009113	2	+	26472758	K562	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	-0.6774731573573849	[1437]	[758]	-4	hSpCas9	negative selection	720485
45008598	45008621	2	+	26472758	K562	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	0.40502095003769567	[551]	[616]	3	hSpCas9	negative selection	720486
45008825	45008848	2	-	26472758	K562	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.10427693123816595	[820]	[744]	0	hSpCas9	negative selection	720487
45009037	45009060	2	-	26472758	K562	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-0.15313134488355573	[327]	[248]	-1	hSpCas9	negative selection	720488
45008976	45008999	2	+	26472758	K562	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	1.3128984655492133	[143]	[301]	9	hSpCas9	negative selection	720489
45008942	45008965	2	-	26472758	K562	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.44444333597444036	[389]	[447]	3	hSpCas9	negative selection	720490
45008929	45008952	2	-	26472758	K562	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.34611412473579795	[177]	[190]	2	hSpCas9	negative selection	720491
45008852	45008875	2	+	26472758	K562	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	-0.31563120308922166	[487]	[330]	-2	hSpCas9	negative selection	720492
45008775	45008798	2	+	26472758	K562	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	-0.1667767053180027	[124]	[93]	-1	hSpCas9	negative selection	720493
45008633	45008656	2	-	26472758	K562	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.3220016686189903	[361]	[381]	2	hSpCas9	negative selection	720494
45006211	45006234	2	+	26627737	DLD1	viability	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-0.5947480150450858	[265]	[31,100,36]	-5	hSpCas9	negative selection	812054
45006427	45006450	2	+	26627737	DLD1	viability	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.30168606037009205	[188]	[42,69,100]	3	hSpCas9	negative selection	812055
45008825	45008848	2	-	26627737	DLD1	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.2317569177119051	[723]	[470,139,191]	2	hSpCas9	negative selection	812056
45009024	45009047	2	-	26627737	DLD1	viability	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-0.26433230831793664	[662]	[229,193,104]	-3	hSpCas9	negative selection	812057
45009072	45009095	2	+	26627737	DLD1	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.4167230147970552	[367]	[204,196,72]	4	hSpCas9	negative selection	812058
45006211	45006234	2	+	26627737	GBM cells	viability after 5 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	0.37756747346050124	[60]	[43,40]	6	hSpCas9	negative selection	894369
45006427	45006450	2	+	26627737	GBM cells	viability after 5 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.8261575324503714	[121]	[97,133]	9	hSpCas9	negative selection	894370
45008825	45008848	2	-	26627737	GBM cells	viability after 5 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.006973620743138564	[359]	[197,189]	0	hSpCas9	negative selection	894371
45009024	45009047	2	-	26627737	GBM cells	viability after 5 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-0.09563169502220627	[263]	[131,132]	-1	hSpCas9	negative selection	894372
45009072	45009095	2	+	26627737	GBM cells	viability after 5 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.7929638297519824	[167]	[60,42]	-8	hSpCas9	negative selection	894373
45006211	45006234	2	+	26627737	GBM cells	viability after 13 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	1.196638846013169	[60]	[71,78]	9	hSpCas9	negative selection	976684
45006427	45006450	2	+	26627737	GBM cells	viability after 13 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.5234529416450917	[121]	[114,78]	6	hSpCas9	negative selection	976685
45008825	45008848	2	-	26627737	GBM cells	viability after 13 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.35222346937886967	[359]	[184,126]	-4	hSpCas9	negative selection	976686
45009024	45009047	2	-	26627737	GBM cells	viability after 13 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-0.38750393617883255	[263]	[146,78]	-4	hSpCas9	negative selection	976687
45009072	45009095	2	+	26627737	GBM cells	viability after 13 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.23820209160111128	[167]	[84,70]	-3	hSpCas9	negative selection	976688
45006211	45006234	2	+	26627737	GBM cells	viability after 21 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	0.8791817725713749	[60]	[61,59]	8	hSpCas9	negative selection	1058999
45006427	45006450	2	+	26627737	GBM cells	viability after 21 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.32298951053987746	[121]	[84,80]	3	hSpCas9	negative selection	1059000
45008825	45008848	2	-	26627737	GBM cells	viability after 21 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.5154610398286034	[359]	[140,132]	-4	hSpCas9	negative selection	1059001
45009024	45009047	2	-	26627737	GBM cells	viability after 21 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-1.8454422813313227	[263]	[41,37]	-8	hSpCas9	negative selection	1059002
45009072	45009095	2	+	26627737	GBM cells	viability after 21 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.030957433426485492	[167]	[104,74]	0	hSpCas9	negative selection	1059003
45006211	45006234	2	+	26627737	RPE1	viability after 9 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-1.4111468603983282	[256]	[0,67]	-7	hSpCas9	negative selection	1141314
45006427	45006450	2	+	26627737	RPE1	viability after 9 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.8505754589012255	[109]	[48,78]	5	hSpCas9	negative selection	1141315
45008825	45008848	2	-	26627737	RPE1	viability after 9 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.5127381756636662	[1732]	[326,448]	-4	hSpCas9	negative selection	1141316
45009024	45009047	2	-	26627737	RPE1	viability after 9 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.17106124319986943	[995]	[323,385]	1	hSpCas9	negative selection	1141317
45009072	45009095	2	+	26627737	RPE1	viability after 9 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.7568311706494533	[595]	[164,39]	-5	hSpCas9	negative selection	1141318
45006211	45006234	2	+	26627737	RPE1	viability after 12 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-0.8834450580408943	[256]	[0,75]	-6	hSpCas9	negative selection	1223629
45006427	45006450	2	+	26627737	RPE1	viability after 12 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	1.2339892861419408	[109]	[86,50]	7	hSpCas9	negative selection	1223630
45008825	45008848	2	-	26627737	RPE1	viability after 12 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.22943028193376613	[1732]	[265,535]	-1	hSpCas9	negative selection	1223631
45009024	45009047	2	-	26627737	RPE1	viability after 12 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-0.2543290798737384	[995]	[235,211]	-2	hSpCas9	negative selection	1223632
45009072	45009095	2	+	26627737	RPE1	viability after 12 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.9258408865974246	[595]	[110,55]	-6	hSpCas9	negative selection	1223633
45006211	45006234	2	+	26627737	RPE1	viability after 15 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-1.2281008662464479	[256]	[0,59]	-6	hSpCas9	negative selection	1305944
45006427	45006450	2	+	26627737	RPE1	viability after 15 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	1.1971071639785897	[109]	[51,89]	6	hSpCas9	negative selection	1305945
45008825	45008848	2	-	26627737	RPE1	viability after 15 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.20395630054168357	[1732]	[526,600]	1	hSpCas9	negative selection	1305946
45009024	45009047	2	-	26627737	RPE1	viability after 15 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-0.21268854941402734	[995]	[235,249]	-1	hSpCas9	negative selection	1305947
45009072	45009095	2	+	26627737	RPE1	viability after 15 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-1.3214747164583718	[595]	[125,10]	-7	hSpCas9	negative selection	1305948
45006211	45006234	2	+	26627737	RPE1	viability after 18 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-1.465278833462397	[256]	[13,36]	-7	hSpCas9	negative selection	1388259
45006427	45006450	2	+	26627737	RPE1	viability after 18 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	1.869576171628877	[109]	[34,186]	8	hSpCas9	negative selection	1388260
45008825	45008848	2	-	26627737	RPE1	viability after 18 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.12179919291382135	[1732]	[307,559]	0	hSpCas9	negative selection	1388261
45009024	45009047	2	-	26627737	RPE1	viability after 18 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-0.6691710568469167	[995]	[169,167]	-4	hSpCas9	negative selection	1388262
45009072	45009095	2	+	26627737	RPE1	viability after 18 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-1.0625361353431906	[595]	[120,29]	-6	hSpCas9	negative selection	1388263
45006211	45006234	2	+	26627737	HeLa	viability after 8 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	0.41139472991653014	[130]	[103,73,56]	4	hSpCas9	negative selection	1470574
45006427	45006450	2	+	26627737	HeLa	viability after 8 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.4766254905138926	[232]	[159,238,35]	4	hSpCas9	negative selection	1470575
45008825	45008848	2	-	26627737	HeLa	viability after 8 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.4655675105862257	[617]	[469,520,159]	4	hSpCas9	negative selection	1470576
45009024	45009047	2	-	26627737	HeLa	viability after 8 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	1.016698203654228	[407]	[720,280,168]	7	hSpCas9	negative selection	1470577
45009072	45009095	2	+	26627737	HeLa	viability after 8 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.08087732666577052	[171]	[26,30,161]	0	hSpCas9	negative selection	1470578
45006211	45006234	2	+	26627737	HeLa	viability after 12 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	1.2489334038268676	[130]	[289,87,16]	8	hSpCas9	negative selection	1552889
45006427	45006450	2	+	26627737	HeLa	viability after 12 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	-0.15541510821316717	[232]	[7,58,192]	-1	hSpCas9	negative selection	1552890
45008825	45008848	2	-	26627737	HeLa	viability after 12 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.22121777746768212	[617]	[364,279,251]	2	hSpCas9	negative selection	1552891
45009024	45009047	2	-	26627737	HeLa	viability after 12 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.49209645982509437	[407]	[243,214,254]	4	hSpCas9	negative selection	1552892
45009072	45009095	2	+	26627737	HeLa	viability after 12 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.2646475642168097	[171]	[105,54,98]	2	hSpCas9	negative selection	1552893
45006211	45006234	2	+	26627737	HeLa	viability after 15 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	0.20757652419859385	[130]	[35,15,138]	1	hSpCas9	negative selection	1635204
45006427	45006450	2	+	26627737	HeLa	viability after 15 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	-0.1616364865022023	[232]	[135,53,61]	-1	hSpCas9	negative selection	1635205
45008825	45008848	2	-	26627737	HeLa	viability after 15 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.01811335483347376	[617]	[308,182,272]	0	hSpCas9	negative selection	1635206
45009024	45009047	2	-	26627737	HeLa	viability after 15 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.3640439689060921	[407]	[320,200,109]	3	hSpCas9	negative selection	1635207
45009072	45009095	2	+	26627737	HeLa	viability after 15 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.4601712144695729	[171]	[97,57,135]	4	hSpCas9	negative selection	1635208
45006211	45006234	2	+	26627737	HeLa	viability after 18 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	0.2578334852773412	[130]	[26,14,138]	2	hSpCas9	negative selection	1717519
45006427	45006450	2	+	26627737	HeLa	viability after 18 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	-0.14098930175030266	[232]	[94,42,61]	-1	hSpCas9	negative selection	1717520
45008825	45008848	2	-	26627737	HeLa	viability after 18 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.04078169506290319	[617]	[209,157,272]	0	hSpCas9	negative selection	1717521
45009024	45009047	2	-	26627737	HeLa	viability after 18 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.37604303889421503	[407]	[219,164,109]	3	hSpCas9	negative selection	1717522
45009072	45009095	2	+	26627737	HeLa	viability after 18 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.49684937177841815	[171]	[68,49,135]	4	hSpCas9	negative selection	1717523
45006211	45006234	2	+	26627737	HCT116	viability after 6 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	0.3520503007934771	[339]	[64,69]	2	hSpCas9	negative selection	1799834
45006427	45006450	2	+	26627737	HCT116	viability after 6 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	1.7446385171202643	[314]	[76,214]	8	hSpCas9	negative selection	1799835
45008825	45008848	2	-	26627737	HCT116	viability after 6 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-1.4384436603689617	[1209]	[162,18]	-7	hSpCas9	negative selection	1799836
45009024	45009047	2	-	26627737	HCT116	viability after 6 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-1.3510706747967727	[1350]	[148,46]	-6	hSpCas9	negative selection	1799837
45009072	45009095	2	+	26627737	HCT116	viability after 6 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-1.3851542389167255	[315]	[38,7]	-7	hSpCas9	negative selection	1799838
45006211	45006234	2	+	26627737	HCT116	viability after 8 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	0.14300137019300374	[105]	[36,91,63]	1	hSpCas9	negative selection	1882149
45006427	45006450	2	+	26627737	HCT116	viability after 8 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.34581568199195134	[141]	[51,106,137]	4	hSpCas9	negative selection	1882150
45008825	45008848	2	-	26627737	HCT116	viability after 8 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.3217247749166404	[628]	[399,227,206]	-4	hSpCas9	negative selection	1882151
45009024	45009047	2	-	26627737	HCT116	viability after 8 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.049205065336766676	[283]	[98,170,213]	0	hSpCas9	negative selection	1882152
45009072	45009095	2	+	26627737	HCT116	viability after 8 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.22185118796264758	[172]	[63,183,84]	2	hSpCas9	negative selection	1882153
45006211	45006234	2	+	26627737	HCT116	viability after 9 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-2.864188763497615	[339]	[7,15]	-9	hSpCas9	negative selection	1964464
45006427	45006450	2	+	26627737	HCT116	viability after 9 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	1.4630343098769842	[314]	[170,279]	8	hSpCas9	negative selection	1964465
45008825	45008848	2	-	26627737	HCT116	viability after 9 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-1.260912728773131	[1209]	[188,91]	-7	hSpCas9	negative selection	1964466
45009024	45009047	2	-	26627737	HCT116	viability after 9 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-0.7922594417228463	[1350]	[109,285]	-5	hSpCas9	negative selection	1964467
45009072	45009095	2	+	26627737	HCT116	viability after 9 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.5745918829229371	[315]	[78,38]	-4	hSpCas9	negative selection	1964468
45006211	45006234	2	+	26627737	HCT116	viability after 12 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	0.3307409385196167	[105]	[103,61,40]	3	hSpCas9	negative selection	2046779
45006427	45006450	2	+	26627737	HCT116	viability after 12 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.31960826454537417	[141]	[56,110,114]	3	hSpCas9	negative selection	2046780
45008825	45008848	2	-	26627737	HCT116	viability after 12 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.028007178637390773	[628]	[395,311,257]	0	hSpCas9	negative selection	2046781
45009024	45009047	2	-	26627737	HCT116	viability after 12 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.41137241861719537	[283]	[136,161,300]	4	hSpCas9	negative selection	2046782
45009072	45009095	2	+	26627737	HCT116	viability after 12 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.7608431067414779	[172]	[72,265,132]	6	hSpCas9	negative selection	2046783
45006211	45006234	2	+	26627737	HCT116	viability after 15 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	0.35898295188322304	[105]	[53,74,101]	3	hSpCas9	negative selection	2129094
45006427	45006450	2	+	26627737	HCT116	viability after 15 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.3239676624733746	[141]	[69,101,129]	3	hSpCas9	negative selection	2129095
45008825	45008848	2	-	26627737	HCT116	viability after 15 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.1714336353684397	[628]	[361,425,180]	-2	hSpCas9	negative selection	2129096
45009024	45009047	2	-	26627737	HCT116	viability after 15 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.1973644218910664	[283]	[208,108,244]	2	hSpCas9	negative selection	2129097
45009072	45009095	2	+	26627737	HCT116	viability after 15 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.40949155839454304	[172]	[135,179,80]	4	hSpCas9	negative selection	2129098
45006211	45006234	2	+	26627737	HCT116	viability after 18 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-0.3357001479491297	[105]	[29,51,38]	-3	hSpCas9	negative selection	2211409
45006427	45006450	2	+	26627737	HCT116	viability after 18 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.9819739828699574	[141]	[73,81,259]	7	hSpCas9	negative selection	2211410
45008825	45008848	2	-	26627737	HCT116	viability after 18 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.4226383806111811	[628]	[401,527,278]	3	hSpCas9	negative selection	2211411
45009024	45009047	2	-	26627737	HCT116	viability after 18 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	1.0577744714431745	[283]	[168,371,311]	7	hSpCas9	negative selection	2211412
45009072	45009095	2	+	26627737	HCT116	viability after 18 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.4950243083323604	[172]	[107,92,155]	4	hSpCas9	negative selection	2211413
45008990	45009013	2	+	24336569	HL60	viability	CGCAGGCGGGCAGCGACCACAGG	SIX2	ENSG00000170577	0.02881795438601434	[427]	[923]	0	hSpCas9	negative selection	2295213
45008996	45009019	2	+	24336569	HL60	viability	CGGGCAGCGACCACAGGAAGCGG	SIX2	ENSG00000170577	0.0027549443438932286	[1230]	[2609]	0	hSpCas9	negative selection	2295214
45009006	45009029	2	-	24336569	HL60	viability	AGCGGCTGGGCCGCTTCCTGTGG	SIX2	ENSG00000170577	0.8297266324132475	[66]	[251]	6	hSpCas9	negative selection	2295215
45009019	45009042	2	-	24336569	HL60	viability	GGCGGCAACATCGAGCGGCTGGG	SIX2	ENSG00000170577	0.8870249266258863	[242]	[950]	7	hSpCas9	negative selection	2295216
45009024	45009047	2	-	24336569	HL60	viability	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	1.4269760246725618	[441]	[2514]	8	hSpCas9	negative selection	2295217
45009037	45009060	2	-	24336569	HL60	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	1.303199749606429	[71]	[375]	8	hSpCas9	negative selection	2295218
45009068	45009091	2	-	24336569	HL60	viability	CGGCTTCACGCAGGAGCAAGTGG	SIX2	ENSG00000170577	-0.08588277189590149	[653]	[1303]	0	hSpCas9	negative selection	2295219
45009075	45009098	2	+	24336569	HL60	viability	CTCCTGCGTGAAGCCGAAGGTGG	SIX2	ENSG00000170577	0.252802328821709	[325]	[821]	2	hSpCas9	negative selection	2295220
45009084	45009107	2	+	24336569	HL60	viability	GAAGCCGAAGGTGGGCAGCATGG	SIX2	ENSG00000170577	-0.14919017835295012	[1122]	[2142]	-1	hSpCas9	negative selection	2295221
45009090	45009113	2	+	24336569	HL60	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	-0.21122530912490567	[1272]	[2326]	-2	hSpCas9	negative selection	2295222
45008990	45009013	2	+	24336569	KBM7	viability	CGCAGGCGGGCAGCGACCACAGG	SIX2	ENSG00000170577	0.33772593188878264	[404]	[1395]	3	hSpCas9	negative selection	2362390
45008996	45009019	2	+	24336569	KBM7	viability	CGGGCAGCGACCACAGGAAGCGG	SIX2	ENSG00000170577	0.31351229497140487	[1185]	[4019]	3	hSpCas9	negative selection	2362391
45009006	45009029	2	-	24336569	KBM7	viability	AGCGGCTGGGCCGCTTCCTGTGG	SIX2	ENSG00000170577	-0.0264414977336207	[58]	[157]	0	hSpCas9	negative selection	2362392
45009019	45009042	2	-	24336569	KBM7	viability	GGCGGCAACATCGAGCGGCTGGG	SIX2	ENSG00000170577	0.9846130237690285	[208]	[1127]	8	hSpCas9	negative selection	2362393
45009024	45009047	2	-	24336569	KBM7	viability	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-0.030421645395669383	[849]	[2269]	0	hSpCas9	negative selection	2362394
45009037	45009060	2	-	24336569	KBM7	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	0.2923579641486146	[193]	[647]	2	hSpCas9	negative selection	2362395
45009068	45009091	2	-	24336569	KBM7	viability	CGGCTTCACGCAGGAGCAAGTGG	SIX2	ENSG00000170577	0.23720017742018784	[455]	[1465]	2	hSpCas9	negative selection	2362396
45009075	45009098	2	+	24336569	KBM7	viability	CTCCTGCGTGAAGCCGAAGGTGG	SIX2	ENSG00000170577	1.2168383157081588	[208]	[1324]	8	hSpCas9	negative selection	2362397
45009084	45009107	2	+	24336569	KBM7	viability	GAAGCCGAAGGTGGGCAGCATGG	SIX2	ENSG00000170577	-0.3196061724669088	[786]	[1719]	-3	hSpCas9	negative selection	2362398
45009090	45009113	2	+	24336569	KBM7	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.05199181294162902	[811]	[2295]	0	hSpCas9	negative selection	2362399
45009088	45009111	2	-	27260157	DLD1	viability	ATGTCCATGCTGCCCACCTTCGG	SIX2	ENSG00000170577	0.601880309297498	[]	[]	8	hSpCas9	negative selection	2573751
45009024	45009047	2	-	27260157	DLD1	viability	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.0801487596438805	[]	[]	3	hSpCas9	negative selection	2574751
45009072	45009095	2	+	27260157	DLD1	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	1.43795515182863	[]	[]	9	hSpCas9	negative selection	2576457
45009037	45009060	2	-	27260157	DLD1	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-0.442510798492515	[]	[]	-4	hSpCas9	negative selection	2576600
45009096	45009119	2	+	27260157	DLD1	viability	GGGCAGCATGGACATGGTGCCGG	SIX2	ENSG00000170577	-1.09419215897469	[]	[]	-7	hSpCas9	negative selection	2605081
45008957	45008980	2	-	27260157	DLD1	viability	CAAGAATGAAAGCGTGCTCAAGG	SIX2	ENSG00000170577	0.799807755941777	[]	[]	9	hSpCas9	negative selection	2605368
45008973	45008996	2	+	27260157	DLD1	viability	ATTCTTGTGAAGGTGCTCGCAGG	SIX2	ENSG00000170577	-0.127688185957137	[]	[]	-1	hSpCas9	negative selection	2606717
45009075	45009098	2	+	27260157	DLD1	viability	CTCCTGCGTGAAGCCGAAGGTGG	SIX2	ENSG00000170577	0.530048242415845	[]	[]	8	hSpCas9	negative selection	2607192
45008996	45009019	2	+	27260157	DLD1	viability	CGGGCAGCGACCACAGGAAGCGG	SIX2	ENSG00000170577	-0.711664674145258	[]	[]	-5	hSpCas9	negative selection	2607687
45008990	45009013	2	+	27260157	DLD1	viability	CGCAGGCGGGCAGCGACCACAGG	SIX2	ENSG00000170577	0.263309383757393	[]	[]	4	hSpCas9	negative selection	2610036
45009068	45009091	2	-	27260157	DLD1	viability	CGGCTTCACGCAGGAGCAAGTGG	SIX2	ENSG00000170577	0.142640378995372	[]	[]	3	hSpCas9	negative selection	2610411
45009090	45009113	2	+	27260157	DLD1	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	-0.199955814148701	[]	[]	-1	hSpCas9	negative selection	2611616
45008870	45008893	2	+	27260157	DLD1	viability	CGTGGTTGTGCGGCGAGAACTGG	SIX2	ENSG00000170577	-0.249117480382251	[]	[]	-2	hSpCas9	negative selection	2617305
45009019	45009042	2	-	27260157	DLD1	viability	GGCGGCAACATCGAGCGGCTGGG	SIX2	ENSG00000170577	0.617111989892588	[]	[]	8	hSpCas9	negative selection	2617343
45009084	45009107	2	+	27260157	DLD1	viability	GAAGCCGAAGGTGGGCAGCATGG	SIX2	ENSG00000170577	0.159290227343734	[]	[]	3	hSpCas9	negative selection	2620273
45008928	45008951	2	+	27260157	DLD1	viability	GCCGCGGTGGAAGGCCACCACGG	SIX2	ENSG00000170577	-0.607573434593501	[]	[]	-5	hSpCas9	negative selection	2621492
45009006	45009029	2	-	27260157	DLD1	viability	AGCGGCTGGGCCGCTTCCTGTGG	SIX2	ENSG00000170577	0.230282527862378	[]	[]	3	hSpCas9	negative selection	2623653
45008963	45008986	2	+	27260157	DLD1	viability	GCACGCTTTCATTCTTGTGAAGG	SIX2	ENSG00000170577	-0.0633103016829956	[]	[]	0	hSpCas9	negative selection	2642676
45008929	45008952	2	-	27260157	DLD1	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	-0.389609868106463	[]	[]	-3	hSpCas9	negative selection	2649250
45008942	45008965	2	-	27260157	DLD1	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	-0.279211011454607	[]	[]	-2	hSpCas9	negative selection	2649323
45009088	45009111	2	-	27260157	HT1080	viability	ATGTCCATGCTGCCCACCTTCGG	SIX2	ENSG00000170577	0.395016446382146	[]	[]	3	hSpCas9	negative selection	2649881
45009024	45009047	2	-	27260157	HT1080	viability	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	1.11918750386717	[]	[]	8	hSpCas9	negative selection	2650881
45009072	45009095	2	+	27260157	HT1080	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.228561443491692	[]	[]	0	hSpCas9	negative selection	2652587
45009037	45009060	2	-	27260157	HT1080	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-1.47076323574183	[]	[]	-9	hSpCas9	negative selection	2652730
45009096	45009119	2	+	27260157	HT1080	viability	GGGCAGCATGGACATGGTGCCGG	SIX2	ENSG00000170577	-0.780515009762857	[]	[]	-8	hSpCas9	negative selection	2681211
45008957	45008980	2	-	27260157	HT1080	viability	CAAGAATGAAAGCGTGCTCAAGG	SIX2	ENSG00000170577	0.428119872075503	[]	[]	4	hSpCas9	negative selection	2681498
45008973	45008996	2	+	27260157	HT1080	viability	ATTCTTGTGAAGGTGCTCGCAGG	SIX2	ENSG00000170577	0.371020399722051	[]	[]	3	hSpCas9	negative selection	2682847
45009075	45009098	2	+	27260157	HT1080	viability	CTCCTGCGTGAAGCCGAAGGTGG	SIX2	ENSG00000170577	0.45452708931236	[]	[]	4	hSpCas9	negative selection	2683322
45008996	45009019	2	+	27260157	HT1080	viability	CGGGCAGCGACCACAGGAAGCGG	SIX2	ENSG00000170577	-0.528833672804334	[]	[]	-7	hSpCas9	negative selection	2683817
45008990	45009013	2	+	27260157	HT1080	viability	CGCAGGCGGGCAGCGACCACAGG	SIX2	ENSG00000170577	-0.399537816387371	[]	[]	-7	hSpCas9	negative selection	2686166
45009068	45009091	2	-	27260157	HT1080	viability	CGGCTTCACGCAGGAGCAAGTGG	SIX2	ENSG00000170577	-0.0901054433301229	[]	[]	0	hSpCas9	negative selection	2686541
45009090	45009113	2	+	27260157	HT1080	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	-0.99893682771163	[]	[]	-8	hSpCas9	negative selection	2687746
45008870	45008893	2	+	27260157	HT1080	viability	CGTGGTTGTGCGGCGAGAACTGG	SIX2	ENSG00000170577	-1.69547325212813	[]	[]	-9	hSpCas9	negative selection	2693435
45009019	45009042	2	-	27260157	HT1080	viability	GGCGGCAACATCGAGCGGCTGGG	SIX2	ENSG00000170577	0.114221814097599	[]	[]	1	hSpCas9	negative selection	2693473
45009084	45009107	2	+	27260157	HT1080	viability	GAAGCCGAAGGTGGGCAGCATGG	SIX2	ENSG00000170577	-0.637831760239886	[]	[]	-8	hSpCas9	negative selection	2696403
45008928	45008951	2	+	27260157	HT1080	viability	GCCGCGGTGGAAGGCCACCACGG	SIX2	ENSG00000170577	-0.502219462152231	[]	[]	-7	hSpCas9	negative selection	2697622
45009006	45009029	2	-	27260157	HT1080	viability	AGCGGCTGGGCCGCTTCCTGTGG	SIX2	ENSG00000170577	-1.14218763696124	[]	[]	-8	hSpCas9	negative selection	2699783
45008963	45008986	2	+	27260157	HT1080	viability	GCACGCTTTCATTCTTGTGAAGG	SIX2	ENSG00000170577	0.148784675855219	[]	[]	1	hSpCas9	negative selection	2718806
45008929	45008952	2	-	27260157	HT1080	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.512990817429801	[]	[]	4	hSpCas9	negative selection	2725380
45008942	45008965	2	-	27260157	HT1080	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	-0.549214101047012	[]	[]	-7	hSpCas9	negative selection	2725453
45009088	45009111	2	-	27260157	MKN45	viability	ATGTCCATGCTGCCCACCTTCGG	SIX2	ENSG00000170577	0.87156267898938	[]	[]	8	hSpCas9	negative selection	2726011
45009024	45009047	2	-	27260157	MKN45	viability	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-0.429325230043347	[]	[]	-6	hSpCas9	negative selection	2727011
45009072	45009095	2	+	27260157	MKN45	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.431666728078684	[]	[]	6	hSpCas9	negative selection	2728717
45009037	45009060	2	-	27260157	MKN45	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-1.17343876637323	[]	[]	-8	hSpCas9	negative selection	2728860
45009096	45009119	2	+	27260157	MKN45	viability	GGGCAGCATGGACATGGTGCCGG	SIX2	ENSG00000170577	0.720612578821373	[]	[]	7	hSpCas9	negative selection	2757341
45008957	45008980	2	-	27260157	MKN45	viability	CAAGAATGAAAGCGTGCTCAAGG	SIX2	ENSG00000170577	1.00769903387086	[]	[]	8	hSpCas9	negative selection	2757628
45008973	45008996	2	+	27260157	MKN45	viability	ATTCTTGTGAAGGTGCTCGCAGG	SIX2	ENSG00000170577	0.45050826865843	[]	[]	6	hSpCas9	negative selection	2758977
45009075	45009098	2	+	27260157	MKN45	viability	CTCCTGCGTGAAGCCGAAGGTGG	SIX2	ENSG00000170577	0.592515770393011	[]	[]	7	hSpCas9	negative selection	2759452
45008996	45009019	2	+	27260157	MKN45	viability	CGGGCAGCGACCACAGGAAGCGG	SIX2	ENSG00000170577	-0.140944199878563	[]	[]	0	hSpCas9	negative selection	2759947
45008990	45009013	2	+	27260157	MKN45	viability	CGCAGGCGGGCAGCGACCACAGG	SIX2	ENSG00000170577	-0.712614709305753	[]	[]	-7	hSpCas9	negative selection	2762296
45009068	45009091	2	-	27260157	MKN45	viability	CGGCTTCACGCAGGAGCAAGTGG	SIX2	ENSG00000170577	-0.546486778364877	[]	[]	-6	hSpCas9	negative selection	2762671
45009090	45009113	2	+	27260157	MKN45	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.0844783026826788	[]	[]	0	hSpCas9	negative selection	2763876
45008870	45008893	2	+	27260157	MKN45	viability	CGTGGTTGTGCGGCGAGAACTGG	SIX2	ENSG00000170577	-0.722059751818564	[]	[]	-7	hSpCas9	negative selection	2769565
45009019	45009042	2	-	27260157	MKN45	viability	GGCGGCAACATCGAGCGGCTGGG	SIX2	ENSG00000170577	1.02189945137464	[]	[]	8	hSpCas9	negative selection	2769603
45009084	45009107	2	+	27260157	MKN45	viability	GAAGCCGAAGGTGGGCAGCATGG	SIX2	ENSG00000170577	1.64995986707531	[]	[]	9	hSpCas9	negative selection	2772533
45008928	45008951	2	+	27260157	MKN45	viability	GCCGCGGTGGAAGGCCACCACGG	SIX2	ENSG00000170577	-0.260189743688771	[]	[]	-1	hSpCas9	negative selection	2773752
45009006	45009029	2	-	27260157	MKN45	viability	AGCGGCTGGGCCGCTTCCTGTGG	SIX2	ENSG00000170577	0.434074753061431	[]	[]	6	hSpCas9	negative selection	2775913
45008963	45008986	2	+	27260157	MKN45	viability	GCACGCTTTCATTCTTGTGAAGG	SIX2	ENSG00000170577	0.649502642421252	[]	[]	7	hSpCas9	negative selection	2794936
45008929	45008952	2	-	27260157	MKN45	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.783565406266943	[]	[]	7	hSpCas9	negative selection	2801510
45008942	45008965	2	-	27260157	MKN45	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.401941085389877	[]	[]	6	hSpCas9	negative selection	2801583
45009088	45009111	2	-	27260157	RKO	viability	ATGTCCATGCTGCCCACCTTCGG	SIX2	ENSG00000170577	0.355013899964353	[]	[]	2	hSpCas9	negative selection	2802141
45009024	45009047	2	-	27260157	RKO	viability	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	1.26874556783749	[]	[]	9	hSpCas9	negative selection	2803141
45009072	45009095	2	+	27260157	RKO	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	1.30912371646421	[]	[]	9	hSpCas9	negative selection	2804847
45009037	45009060	2	-	27260157	RKO	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-1.95333605975739	[]	[]	-9	hSpCas9	negative selection	2804990
45009096	45009119	2	+	27260157	RKO	viability	GGGCAGCATGGACATGGTGCCGG	SIX2	ENSG00000170577	-0.30612009336851	[]	[]	-6	hSpCas9	negative selection	2833471
45008957	45008980	2	-	27260157	RKO	viability	CAAGAATGAAAGCGTGCTCAAGG	SIX2	ENSG00000170577	0.795879833948899	[]	[]	8	hSpCas9	negative selection	2833758
45008973	45008996	2	+	27260157	RKO	viability	ATTCTTGTGAAGGTGCTCGCAGG	SIX2	ENSG00000170577	-0.355312028869302	[]	[]	-6	hSpCas9	negative selection	2835107
45009075	45009098	2	+	27260157	RKO	viability	CTCCTGCGTGAAGCCGAAGGTGG	SIX2	ENSG00000170577	0.924052642060469	[]	[]	8	hSpCas9	negative selection	2835582
45008996	45009019	2	+	27260157	RKO	viability	CGGGCAGCGACCACAGGAAGCGG	SIX2	ENSG00000170577	1.02164574621152	[]	[]	9	hSpCas9	negative selection	2836077
45008990	45009013	2	+	27260157	RKO	viability	CGCAGGCGGGCAGCGACCACAGG	SIX2	ENSG00000170577	0.0134861336125598	[]	[]	0	hSpCas9	negative selection	2838426
45009068	45009091	2	-	27260157	RKO	viability	CGGCTTCACGCAGGAGCAAGTGG	SIX2	ENSG00000170577	0.778781070546677	[]	[]	8	hSpCas9	negative selection	2838801
45009090	45009113	2	+	27260157	RKO	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	-0.0944773252154622	[]	[]	0	hSpCas9	negative selection	2840006
45008870	45008893	2	+	27260157	RKO	viability	CGTGGTTGTGCGGCGAGAACTGG	SIX2	ENSG00000170577	-0.647115753639579	[]	[]	-7	hSpCas9	negative selection	2845695
45009019	45009042	2	-	27260157	RKO	viability	GGCGGCAACATCGAGCGGCTGGG	SIX2	ENSG00000170577	1.07222396558317	[]	[]	9	hSpCas9	negative selection	2845733
45009084	45009107	2	+	27260157	RKO	viability	GAAGCCGAAGGTGGGCAGCATGG	SIX2	ENSG00000170577	0.769537300046486	[]	[]	8	hSpCas9	negative selection	2848663
45008928	45008951	2	+	27260157	RKO	viability	GCCGCGGTGGAAGGCCACCACGG	SIX2	ENSG00000170577	-0.0681344581540591	[]	[]	0	hSpCas9	negative selection	2849882
45009006	45009029	2	-	27260157	RKO	viability	AGCGGCTGGGCCGCTTCCTGTGG	SIX2	ENSG00000170577	-0.189314631913272	[]	[]	-1	hSpCas9	negative selection	2852043
45008963	45008986	2	+	27260157	RKO	viability	GCACGCTTTCATTCTTGTGAAGG	SIX2	ENSG00000170577	0.0221494690879779	[]	[]	0	hSpCas9	negative selection	2871066
45008929	45008952	2	-	27260157	RKO	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.555064670061828	[]	[]	3	hSpCas9	negative selection	2877640
45008942	45008965	2	-	27260157	RKO	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.0210838601330308	[]	[]	0	hSpCas9	negative selection	2877713
45009088	45009111	2	-	27260157	SF268	viability	ATGTCCATGCTGCCCACCTTCGG	SIX2	ENSG00000170577	-0.565348977052944	[]	[]	-4	hSpCas9	negative selection	2878271
45009024	45009047	2	-	27260157	SF268	viability	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.981689231128197	[]	[]	9	hSpCas9	negative selection	2879271
45009072	45009095	2	+	27260157	SF268	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.777481915630951	[]	[]	8	hSpCas9	negative selection	2880977
45009037	45009060	2	-	27260157	SF268	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-0.720658897173135	[]	[]	-5	hSpCas9	negative selection	2881120
45009096	45009119	2	+	27260157	SF268	viability	GGGCAGCATGGACATGGTGCCGG	SIX2	ENSG00000170577	-1.71178978642083	[]	[]	-8	hSpCas9	negative selection	2909601
45008957	45008980	2	-	27260157	SF268	viability	CAAGAATGAAAGCGTGCTCAAGG	SIX2	ENSG00000170577	-0.37955596940544	[]	[]	-3	hSpCas9	negative selection	2909888
45008973	45008996	2	+	27260157	SF268	viability	ATTCTTGTGAAGGTGCTCGCAGG	SIX2	ENSG00000170577	-0.0887120474388759	[]	[]	0	hSpCas9	negative selection	2911237
45009075	45009098	2	+	27260157	SF268	viability	CTCCTGCGTGAAGCCGAAGGTGG	SIX2	ENSG00000170577	-0.188678753532187	[]	[]	-1	hSpCas9	negative selection	2911712
45008996	45009019	2	+	27260157	SF268	viability	CGGGCAGCGACCACAGGAAGCGG	SIX2	ENSG00000170577	-0.176384532350663	[]	[]	-1	hSpCas9	negative selection	2912207
45008990	45009013	2	+	27260157	SF268	viability	CGCAGGCGGGCAGCGACCACAGG	SIX2	ENSG00000170577	-0.339302435063505	[]	[]	-3	hSpCas9	negative selection	2914556
45009068	45009091	2	-	27260157	SF268	viability	CGGCTTCACGCAGGAGCAAGTGG	SIX2	ENSG00000170577	-0.117034996014839	[]	[]	-1	hSpCas9	negative selection	2914931
45009090	45009113	2	+	27260157	SF268	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	-0.597107130960431	[]	[]	-4	hSpCas9	negative selection	2916136
45008870	45008893	2	+	27260157	SF268	viability	CGTGGTTGTGCGGCGAGAACTGG	SIX2	ENSG00000170577	-1.6318731727593	[]	[]	-8	hSpCas9	negative selection	2921825
45009019	45009042	2	-	27260157	SF268	viability	GGCGGCAACATCGAGCGGCTGGG	SIX2	ENSG00000170577	-0.491043005099802	[]	[]	-4	hSpCas9	negative selection	2921863
45009084	45009107	2	+	27260157	SF268	viability	GAAGCCGAAGGTGGGCAGCATGG	SIX2	ENSG00000170577	0.489266048333574	[]	[]	7	hSpCas9	negative selection	2924793
45008928	45008951	2	+	27260157	SF268	viability	GCCGCGGTGGAAGGCCACCACGG	SIX2	ENSG00000170577	0.539429251337531	[]	[]	8	hSpCas9	negative selection	2926012
45009006	45009029	2	-	27260157	SF268	viability	AGCGGCTGGGCCGCTTCCTGTGG	SIX2	ENSG00000170577	-0.945732793719379	[]	[]	-6	hSpCas9	negative selection	2928173
45008963	45008986	2	+	27260157	SF268	viability	GCACGCTTTCATTCTTGTGAAGG	SIX2	ENSG00000170577	-0.479178397202019	[]	[]	-4	hSpCas9	negative selection	2947196
45008929	45008952	2	-	27260157	SF268	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.265477853999255	[]	[]	4	hSpCas9	negative selection	2953770
45008942	45008965	2	-	27260157	SF268	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	-0.453315943520915	[]	[]	-4	hSpCas9	negative selection	2953843
45008913	45008936	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAGCTCGCGGAAGTTGCCGCGG	SIX2	ENSG00000170577	-0.3553110920706276	[2,3]	[1,2]	-5	hSpCas9	positive selection	3020418
45008812	45008835	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATCGAGGCGGAGAAGCTGCGCGG	SIX2	ENSG00000170577	-0.1473894275789546	[3,3]	[3,1]	-2	hSpCas9	positive selection	3020419
45008929	45008952	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.07140492868239892	[4,4]	[2,4]	1	hSpCas9	positive selection	3020420
45008738	45008761	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCGCCGTCCCAGATGGAGCGCGG	SIX2	ENSG00000170577	-0.30623107514308323	[2,3]	[3,0]	-4	hSpCas9	positive selection	3020421
45008913	45008936	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAGCTCGCGGAAGTTGCCGCGG	SIX2	ENSG00000170577	-0.46169242771494573	[2,2]	[1,0]	-6	hSpCas9	positive selection	3088276
45008812	45008835	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATCGAGGCGGAGAAGCTGCGCGG	SIX2	ENSG00000170577	-0.5085688729979846	[3,3]	[2,0]	-7	hSpCas9	positive selection	3088277
45008929	45008952	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.26363720893217696	[4,4]	[4,3]	4	hSpCas9	positive selection	3088278
45008738	45008761	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCGCCGTCCCAGATGGAGCGCGG	SIX2	ENSG00000170577	-0.22255646196065976	[2,2]	[2,0]	-3	hSpCas9	positive selection	3088279
45006438	45006461		-	24336571	A375	resistance to PLX after 7 days	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	-0.24637196567501246	[9,9]	[6,8]	-7	hSpCas9	positive selection	3144373
45006372	45006395		+	24336571	A375	resistance to PLX after 7 days	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.1781181475367849	[6,6]	[5,5]	-5	hSpCas9	positive selection	3144374
45008762	45008785		+	24336571	A375	resistance to PLX after 7 days	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.09785752275579251	[2,3]	[3,2]	-3	hSpCas9	positive selection	3144375
45006183	45006206		+	24336571	A375	resistance to PLX after 7 days	TCCACGAGGTTGGCTGACATGGG	SIX2	ENSG00000170577	-0.02625699976619436	[13,10]	[12,11]	0	hSpCas9	positive selection	3144376
45006438	45006461		-	24336571	A375	resistance to PLX after 14 days	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	-0.4175909662921363	[9,8]	[2,2]	-5	hSpCas9	positive selection	3202166
45006372	45006395		+	24336571	A375	resistance to PLX after 14 days	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.7004926339777464	[5,3]	[2,3]	6	hSpCas9	positive selection	3202167
45008762	45008785		+	24336571	A375	resistance to PLX after 14 days	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.1533158326687054	[5,4]	[1,1]	-2	hSpCas9	positive selection	3202168
45006183	45006206		+	24336571	A375	resistance to PLX after 14 days	TCCACGAGGTTGGCTGACATGGG	SIX2	ENSG00000170577	0.881626561717349	[6,6]	[5,6]	7	hSpCas9	positive selection	3202169
45006438	45006461		-	24336571	A375	viability after 7 days	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.24138806958155262	[8]	[9,9]	3	hSpCas9	negative selection	3259959
45006372	45006395		+	24336571	A375	viability after 7 days	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.04148229072453402	[6]	[6,6]	0	hSpCas9	negative selection	3259960
45008762	45008785		+	24336571	A375	viability after 7 days	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.45123921106346354	[4]	[2,3]	-6	hSpCas9	negative selection	3259961
45006183	45006206		+	24336571	A375	viability after 7 days	TCCACGAGGTTGGCTGACATGGG	SIX2	ENSG00000170577	0.22638329381144368	[10]	[13,10]	3	hSpCas9	negative selection	3259962
45006438	45006461		-	24336571	A375	viability after 14 days	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.26815141539534504	[8]	[9,8]	3	hSpCas9	negative selection	3317752
45006372	45006395		+	24336571	A375	viability after 14 days	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.4020887559044056	[6]	[5,3]	-5	hSpCas9	negative selection	3317753
45008762	45008785		+	24336571	A375	viability after 14 days	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.1890755089352616	[4]	[5,4]	2	hSpCas9	negative selection	3317754
45006183	45006206		+	24336571	A375	viability after 14 days	TCCACGAGGTTGGCTGACATGGG	SIX2	ENSG00000170577	-0.5395376810130181	[10]	[6,6]	-6	hSpCas9	negative selection	3317755
45006438	45006461	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.4371472490306473	[112,112]	[0,0]	2	hSpCas9	positive selection	3392532
45009072	45009095	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.21293209208738176	[131,131]	[0,0]	1	hSpCas9	positive selection	3392533
45008825	45008848	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	1.1698633701954957	[67,67]	[0,0]	5	hSpCas9	positive selection	3392534
45008912	45008935	2	+	26780180	HT29	viability (Avana library 4 designs)	AGAGCTCGCGGAAGTTGCCGCGG	SIX2	ENSG00000170577	1.06541720726941	[]	[]	4	hSpCas9	negative selection	3458930
45008812	45008835	2	-	26780180	HT29	viability (Avana library 4 designs)	ATCGAGGCGGAGAAGCTGCGCGG	SIX2	ENSG00000170577	1.26573222172563	[]	[]	5	hSpCas9	negative selection	3458931
45008929	45008952	2	-	26780180	HT29	viability (Avana library 4 designs)	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	-0.0393988627050744	[]	[]	0	hSpCas9	negative selection	3458932
45008737	45008760	2	+	26780180	HT29	viability (Avana library 4 designs)	TCGCCGTCCCAGATGGAGCGCGG	SIX2	ENSG00000170577	1.47102094503417	[]	[]	6	hSpCas9	negative selection	3458933
45008812	45008835	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATCGAGGCGGAGAAGCTGCGCGG	SIX2	ENSG00000170577	4.0859630468581	[]	[]	6	hSpCas9	negative selection	3558609
45008912	45008935	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGCTCGCGGAAGTTGCCGCGG	SIX2	ENSG00000170577	-0.46698992558347	[]	[]	0	hSpCas9	negative selection	3558610
45008737	45008760	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCGCCGTCCCAGATGGAGCGCGG	SIX2	ENSG00000170577	6.14645086427628	[]	[]	9	hSpCas9	negative selection	3558611
45008929	45008952	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	5.54865416194056	[]	[]	8	hSpCas9	negative selection	3558612
45009024	45009047	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	2.81580484795125	[]	[]	4	hSpCas9	negative selection	3558613
45008775	45008798	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	4.9018264064312	[]	[]	8	hSpCas9	negative selection	3558614
45008812	45008835	2	-	26780180	A375	viability (Avana lentiGuide)	ATCGAGGCGGAGAAGCTGCGCGG	SIX2	ENSG00000170577	-0.677622324015114	[]	[]	-1	hSpCas9	negative selection	3667268
45008912	45008935	2	+	26780180	A375	viability (Avana lentiGuide)	AGAGCTCGCGGAAGTTGCCGCGG	SIX2	ENSG00000170577	6.65492125889417	[]	[]	5	hSpCas9	negative selection	3667269
45008737	45008760	2	+	26780180	A375	viability (Avana lentiGuide)	TCGCCGTCCCAGATGGAGCGCGG	SIX2	ENSG00000170577	-0.236111819601711	[]	[]	0	hSpCas9	negative selection	3667270
45008929	45008952	2	-	26780180	A375	viability (Avana lentiGuide)	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	-0.92802863983384	[]	[]	-1	hSpCas9	negative selection	3667271
45009024	45009047	2	-	26780180	A375	viability (Avana lentiGuide)	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	5.42663662110879	[]	[]	5	hSpCas9	negative selection	3667272
45008775	45008798	2	+	26780180	A375	viability (Avana lentiGuide)	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	-2.19638878788693	[]	[]	-4	hSpCas9	negative selection	3667273
45008812	45008835	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCGAGGCGGAGAAGCTGCGCGG	SIX2	ENSG00000170577	0.4918323749792919	[4]	[6,7]	9	hSpCas9	positive selection	3775875
45008912	45008935	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGCTCGCGGAAGTTGCCGCGG	SIX2	ENSG00000170577	-0.02344024478014589	[4]	[4,4]	0	hSpCas9	positive selection	3775876
45008737	45008760	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCGCCGTCCCAGATGGAGCGCGG	SIX2	ENSG00000170577	-0.0056152451550585125	[3]	[4,3]	0	hSpCas9	positive selection	3775877
45008929	45008952	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.3970604791292564	[5]	[6,6]	9	hSpCas9	positive selection	3775878
45009024	45009047	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.12477961997215539	[4]	[4,3]	3	hSpCas9	positive selection	3775879
45008775	45008798	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	0.29645923359551785	[4]	[4,6]	8	hSpCas9	positive selection	3775880
45008812	45008835	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCGAGGCGGAGAAGCTGCGCGG	SIX2	ENSG00000170577	0.2430673823101121	[5]	[5,5]	6	hSpCas9	positive selection	3884482
45008912	45008935	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGCTCGCGGAAGTTGCCGCGG	SIX2	ENSG00000170577	-0.5568456695238975	[5]	[2,2]	-6	hSpCas9	positive selection	3884483
45008737	45008760	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCGCCGTCCCAGATGGAGCGCGG	SIX2	ENSG00000170577	0.30563203812106654	[5]	[4,5]	8	hSpCas9	positive selection	3884484
45008929	45008952	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.2768136769494919	[6]	[6,6]	7	hSpCas9	positive selection	3884485
45009024	45009047	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-0.20265423593978013	[4]	[1,4]	-3	hSpCas9	positive selection	3884486
45008775	45008798	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	-0.11254295775544632	[5]	[5,2]	-1	hSpCas9	positive selection	3884487
45006438	45006461	2	-	26780180	A375	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	1.54913437330906	[]	[]	8	hSpCas9	negative selection	3994538
45008639	45008662	2	-	26780180	A375	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	1.26903949244698	[]	[]	7	hSpCas9	negative selection	3994539
45008825	45008848	2	-	26780180	A375	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	1.29516465901929	[]	[]	7	hSpCas9	negative selection	3994540
45006372	45006395	2	+	26780180	A375	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	1.2765599539132	[]	[]	7	hSpCas9	negative selection	3994541
45008762	45008785	2	+	26780180	A375	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.529724352664267	[]	[]	1	hSpCas9	negative selection	3994542
45009072	45009095	2	+	26780180	A375	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	1.39259691333891	[]	[]	7	hSpCas9	negative selection	3994543
45006438	45006461	2	-	26780180	HT29	viability (GeCKOv2 library)	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	1.2076611418622	[]	[]	6	hSpCas9	negative selection	4102504
45008639	45008662	2	-	26780180	HT29	viability (GeCKOv2 library)	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	1.0783614269328	[]	[]	5	hSpCas9	negative selection	4102505
45008825	45008848	2	-	26780180	HT29	viability (GeCKOv2 library)	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	1.51711216817247	[]	[]	7	hSpCas9	negative selection	4102506
45006372	45006395	2	+	26780180	HT29	viability (GeCKOv2 library)	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.391758272584239	[]	[]	1	hSpCas9	negative selection	4102507
45008762	45008785	2	+	26780180	HT29	viability (GeCKOv2 library)	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.515358872911921	[]	[]	1	hSpCas9	negative selection	4102508
45009072	45009095	2	+	26780180	HT29	viability (GeCKOv2 library)	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	1.04275683308057	[]	[]	5	hSpCas9	negative selection	4102509
45006438	45006461	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	-0.2131364933280174	[3]	[1,1]	-5	hSpCas9	positive selection	4170325
45006372	45006395	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.2981763303802481	[3]	[1,1]	-6	hSpCas9	positive selection	4170326
45008762	45008785	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.0960901359082208	[2]	[1,0]	-2	hSpCas9	positive selection	4170327
45006183	45006206	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCACGAGGTTGGCTGACATGGG	SIX2	ENSG00000170577	0.2501512699353648	[3]	[2,2]	6	hSpCas9	positive selection	4170328
45006438	45006461	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.9815052730392024	[1]	[1,0,4,0]	7	hSpCas9	positive selection	4234347
45006372	45006395	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.6993730489056124	[2]	[1,2,4,0]	4	hSpCas9	positive selection	4234348
45008762	45008785	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.29785857270727156	[1]	[0,0,0,0]	-4	hSpCas9	positive selection	4234349
45006183	45006206	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCACGAGGTTGGCTGACATGGG	SIX2	ENSG00000170577	-0.6579201738011605	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4234350
45008762	45008785	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.01755983842780484	[1]	[1,0]	0	hSpCas9	positive selection	4297876
45008639	45008662	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.305621035932804	[2]	[1,0]	-6	hSpCas9	positive selection	4297877
45006372	45006395	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.15578398205587865	[2]	[2,1]	3	hSpCas9	positive selection	4297878
45006438	45006461	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	-0.054857187059509815	[2]	[2,1]	-1	hSpCas9	positive selection	4362130
45009072	45009095	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.11824216031455692	[3]	[2,1]	-2	hSpCas9	positive selection	4362131
45008825	45008848	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.3462264534954445	[2]	[2,0]	-6	hSpCas9	positive selection	4362132
45006447	45006469	2	+	27760321	OCIAML3	viability	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	0.5223228684441751	[393,328]	[439,357]	6	hSpCas9	negative selection	4439137
45008545	45008567	2	+	27760321	OCIAML3	viability	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.7675472794372977	[653,541]	[750,846]	8	hSpCas9	negative selection	4439138
45008645	45008667	2	+	27760321	OCIAML3	viability	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	-0.061597394885397894	[601,547]	[378,497]	0	hSpCas9	negative selection	4439139
45008828	45008850	2	-	27760321	OCIAML3	viability	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	-0.33360104535656554	[327,277]	[133,256]	-4	hSpCas9	negative selection	4439140
45009020	45009042	2	-	27760321	OCIAML3	viability	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	0.6829723409072525	[889,726]	[924,1120]	7	hSpCas9	negative selection	4439141
45006447	45006469	2	+	27760321	OCIAML2	viability	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	0.5938272278986438	[393,328]	[316,600]	7	hSpCas9	negative selection	4522600
45008545	45008567	2	+	27760321	OCIAML2	viability	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.37886909769130883	[653,541]	[523,760]	5	hSpCas9	negative selection	4522601
45008645	45008667	2	+	27760321	OCIAML2	viability	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	0.42552514906884614	[601,547]	[569,695]	6	hSpCas9	negative selection	4522602
45008828	45008850	2	-	27760321	OCIAML2	viability	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	0.1725987914218562	[327,277]	[251,305]	2	hSpCas9	negative selection	4522603
45009020	45009042	2	-	27760321	OCIAML2	viability	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	0.4241562252939207	[889,726]	[779,995]	6	hSpCas9	negative selection	4522604
45006447	45006469	2	+	27760321	MV411	viability	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	0.4241476855326382	[393,328]	[289,361]	3	hSpCas9	negative selection	4606063
45008545	45008567	2	+	27760321	MV411	viability	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.7739511098149996	[653,541]	[441,1016]	6	hSpCas9	negative selection	4606064
45008645	45008667	2	+	27760321	MV411	viability	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	0.19477827250129603	[601,547]	[485,355]	1	hSpCas9	negative selection	4606065
45008828	45008850	2	-	27760321	MV411	viability	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	-0.31152451929574765	[327,277]	[106,240]	-2	hSpCas9	negative selection	4606066
45009020	45009042	2	-	27760321	MV411	viability	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	0.26250269509013	[889,726]	[402,987]	1	hSpCas9	negative selection	4606067
45006447	45006469	2	+	27760321	HL60	viability	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	0.8434828361319113	[393,328]	[600,449]	8	hSpCas9	negative selection	4689526
45008545	45008567	2	+	27760321	HL60	viability	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.10005390412040915	[653,541]	[496,546]	1	hSpCas9	negative selection	4689527
45008645	45008667	2	+	27760321	HL60	viability	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	0.06149419371047393	[601,547]	[518,458]	0	hSpCas9	negative selection	4689528
45008828	45008850	2	-	27760321	HL60	viability	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	0.5152159247027043	[327,277]	[352,351]	6	hSpCas9	negative selection	4689529
45009020	45009042	2	-	27760321	HL60	viability	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	0.27259833911719944	[889,726]	[903,676]	3	hSpCas9	negative selection	4689530
45006447	45006469	2	+	27760321	HT1080	viability	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	-0.6450529050112606	[328,256]	[24,128]	-3	hSpCas9	negative selection	4772989
45008545	45008567	2	+	27760321	HT1080	viability	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.2500675098376445	[541,422]	[219,237]	1	hSpCas9	negative selection	4772990
45008645	45008667	2	+	27760321	HT1080	viability	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	0.672540160107433	[547,427]	[401,208]	3	hSpCas9	negative selection	4772991
45008828	45008850	2	-	27760321	HT1080	viability	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	0.9038194244367925	[277,216]	[183,184]	5	hSpCas9	negative selection	4772992
45009020	45009042	2	-	27760321	HT1080	viability	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	-0.6288099797202784	[726,566]	[180,150]	-3	hSpCas9	negative selection	4772993
45006447	45006469	2	+	27760321	HT29	viability after 7 days	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	0.2537323257151835	[328,256]	[658,306,411]	4	hSpCas9	negative selection	4856452
45008545	45008567	2	+	27760321	HT29	viability after 7 days	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.3708730009934531	[541,422]	[878,817,721]	5	hSpCas9	negative selection	4856453
45008645	45008667	2	+	27760321	HT29	viability after 7 days	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	0.5524213342987004	[547,427]	[1036,980,762]	8	hSpCas9	negative selection	4856454
45008828	45008850	2	-	27760321	HT29	viability after 7 days	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	-0.12007412084273095	[277,216]	[423,284,190]	-2	hSpCas9	negative selection	4856455
45009020	45009042	2	-	27760321	HT29	viability after 7 days	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	0.741619563703484	[726,566]	[1741,1227,1254]	9	hSpCas9	negative selection	4856456
45006447	45006469	2	+	27760321	HT29	viability after 25 days	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	-0.01902930565908112	[328,256]	[217,397,387]	0	hSpCas9	negative selection	4939915
45008545	45008567	2	+	27760321	HT29	viability after 25 days	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.930598994058767	[541,422]	[773,722,1743]	9	hSpCas9	negative selection	4939916
45008645	45008667	2	+	27760321	HT29	viability after 25 days	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	-0.013605748596325407	[547,427]	[444,496,740]	0	hSpCas9	negative selection	4939917
45008828	45008850	2	-	27760321	HT29	viability after 25 days	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	0.03153492363271704	[277,216]	[273,216,386]	0	hSpCas9	negative selection	4939918
45009020	45009042	2	-	27760321	HT29	viability after 25 days	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	0.8155398114231355	[726,566]	[1358,1118,1433]	8	hSpCas9	negative selection	4939919
45006447	45006469	2	+	27760321	HT29	viability after 22 days	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	0.09397638466240615	[328,256]	[315,286,483]	0	hSpCas9	negative selection	5023378
45008545	45008567	2	+	27760321	HT29	viability after 22 days	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.5351131246610193	[541,422]	[548,843,1040]	6	hSpCas9	negative selection	5023379
45008645	45008667	2	+	27760321	HT29	viability after 22 days	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	0.16897060362184146	[547,427]	[510,775,618]	1	hSpCas9	negative selection	5023380
45008828	45008850	2	-	27760321	HT29	viability after 22 days	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	0.9156470387538734	[277,216]	[676,452,484]	9	hSpCas9	negative selection	5023381
45009020	45009042	2	-	27760321	HT29	viability after 22 days	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	0.5331869033196875	[726,566]	[1230,927,1083]	6	hSpCas9	negative selection	5023382
45006447	45006469	2	+	27760321	HT29	viability after 19 days	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	-0.008526289813505394	[328,256]	[322,391,284]	0	hSpCas9	negative selection	5106841
45008545	45008567	2	+	27760321	HT29	viability after 19 days	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.5731008066414727	[541,422]	[678,720,1038]	6	hSpCas9	negative selection	5106842
45008645	45008667	2	+	27760321	HT29	viability after 19 days	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	-0.005032479782130006	[547,427]	[702,408,570]	0	hSpCas9	negative selection	5106843
45008828	45008850	2	-	27760321	HT29	viability after 19 days	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	0.5456756917093732	[277,216]	[540,521,197]	5	hSpCas9	negative selection	5106844
45009020	45009042	2	-	27760321	HT29	viability after 19 days	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	1.1573571224811716	[726,566]	[1849,1712,1416]	9	hSpCas9	negative selection	5106845
45006447	45006469	2	+	27760321	HT29	viability after 16 days	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	0.15078199357304015	[328,256]	[183,431,456]	1	hSpCas9	negative selection	5190304
45008545	45008567	2	+	27760321	HT29	viability after 16 days	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.8619311966131421	[541,422]	[886,608,1447]	8	hSpCas9	negative selection	5190305
45008645	45008667	2	+	27760321	HT29	viability after 16 days	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	0.44278072425453263	[547,427]	[794,752,682]	5	hSpCas9	negative selection	5190306
45008828	45008850	2	-	27760321	HT29	viability after 16 days	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	0.7753438479768822	[277,216]	[457,292,673]	8	hSpCas9	negative selection	5190307
45009020	45009042	2	-	27760321	HT29	viability after 16 days	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	1.0227304148333118	[726,566]	[1657,1410,1361]	9	hSpCas9	negative selection	5190308
45006447	45006469	2	+	27760321	HT29	viability after 13 days	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	-0.3198427229967579	[328,256]	[263,280,271]	-4	hSpCas9	negative selection	5273767
45008545	45008567	2	+	27760321	HT29	viability after 13 days	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.6628215728061212	[541,422]	[741,898,1009]	8	hSpCas9	negative selection	5273768
45008645	45008667	2	+	27760321	HT29	viability after 13 days	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	0.055238975573399796	[547,427]	[679,590,498]	0	hSpCas9	negative selection	5273769
45008828	45008850	2	-	27760321	HT29	viability after 13 days	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	0.576821477911163	[277,216]	[629,357,303]	7	hSpCas9	negative selection	5273770
45009020	45009042	2	-	27760321	HT29	viability after 13 days	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	0.7011459319514498	[726,566]	[1719,1036,920]	8	hSpCas9	negative selection	5273771
45006447	45006469	2	+	27760321	HT29	viability after 10 days	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	0.4228896652075871	[328,256]	[446,483,538]	6	hSpCas9	negative selection	5357230
45008545	45008567	2	+	27760321	HT29	viability after 10 days	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	0.49425470096149604	[541,422]	[715,795,1027]	6	hSpCas9	negative selection	5357231
45008645	45008667	2	+	27760321	HT29	viability after 10 days	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	0.17862263798351918	[547,427]	[682,716,669]	2	hSpCas9	negative selection	5357232
45008828	45008850	2	-	27760321	HT29	viability after 10 days	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	0.015265749739193368	[277,216]	[459,328,151]	0	hSpCas9	negative selection	5357233
45009020	45009042	2	-	27760321	HT29	viability after 10 days	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	0.6928276802659771	[726,566]	[1746,867,1289]	8	hSpCas9	negative selection	5357234
45006447	45006469	2	+	27760321	MOLM13	viability	GGGTTGTGGCTGTTAGAATTGG	SIX2	ENSG00000170577	0.48303154609429366	[393,328]	[22,505]	3	hSpCas9	negative selection	5440693
45008545	45008567	2	+	27760321	MOLM13	viability	TCGTACCTTTCCTTGGCCTCGG	SIX2	ENSG00000170577	1.490991597147143	[653,541]	[598,1237]	9	hSpCas9	negative selection	5440694
45008645	45008667	2	+	27760321	MOLM13	viability	CACGCTTCTCGCGGGGTGAAGG	SIX2	ENSG00000170577	0.34076703399234715	[601,547]	[240,554]	2	hSpCas9	negative selection	5440695
45008828	45008850	2	-	27760321	MOLM13	viability	CTCAAGGCACACTACATCGAGG	SIX2	ENSG00000170577	-0.8434559994170678	[327,277]	[162,36]	-5	hSpCas9	negative selection	5440696
45009020	45009042	2	-	27760321	MOLM13	viability	GGCGGCAACATCGAGCGGCTGG	SIX2	ENSG00000170577	0.9816246380291181	[889,726]	[1228,612]	7	hSpCas9	negative selection	5440697
45009249	45009272	2	-	27661255	K562	viability	GGACGTACGGCAGTGACTCGGGG	SIX2	ENSG00000170577	0.13604574929974778	[1411,1437]	[1318,1191]	5	dCas9-KRAB	negative selection	5511177
45009262	45009285	2	-	27661255	K562	viability	GCGGCCGGCGCGGGGACGTACGG	SIX2	ENSG00000170577	-0.017427249586979277	[585,570]	[513,407]	0	dCas9-KRAB	negative selection	5511178
45009370	45009393	2	-	27661255	K562	viability	GCGGGCGGGCGCGGAGCATGCGG	SIX2	ENSG00000170577	-0.2549339261558105	[587,554]	[423,347]	-6	dCas9-KRAB	negative selection	5511179
45009392	45009415	2	-	27661255	K562	viability	GTGAGAAGCGAGCGAGGGAACGG	SIX2	ENSG00000170577	0.17510186310320486	[185,288]	[218,206]	6	dCas9-KRAB	negative selection	5511180
45008762	45008785	2	+	27260156	BXPC3	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.29446374255063557	[87]	[186,97,52,102]	6	hSpCas9	negative selection	5570336
45008639	45008662	2	-	27260156	BXPC3	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.08360271226763916	[280]	[290,343,305,300]	1	hSpCas9	negative selection	5570337
45006372	45006395	2	+	27260156	BXPC3	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.05100653444532577	[303]	[210,351,331,445]	1	hSpCas9	negative selection	5570338
45006438	45006461	2	-	27260156	BXPC3	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.14736673838699432	[380]	[363,470,478,456]	3	hSpCas9	negative selection	5634590
45009072	45009095	2	+	27260156	BXPC3	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.2880607206324707	[493]	[347,371,475,516]	-6	hSpCas9	negative selection	5634591
45008825	45008848	2	-	27260156	BXPC3	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.7754686766469241	[325]	[253,145,193,197]	-9	hSpCas9	negative selection	5634592
45008762	45008785	2	+	27260156	A673	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.33345227470052574	[87]	[119,104,145,161]	7	hSpCas9	negative selection	5691587
45008639	45008662	2	-	27260156	A673	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.009128581282539128	[280]	[294,373,319,363]	0	hSpCas9	negative selection	5691588
45006372	45006395	2	+	27260156	A673	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.03648986545261623	[303]	[318,372,341,385]	-1	hSpCas9	negative selection	5691589
45006438	45006461	2	-	27260156	A673	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.0031799670887413534	[380]	[498,448,419,470]	0	hSpCas9	negative selection	5755841
45009072	45009095	2	+	27260156	A673	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.17156316507350117	[493]	[519,557,531,491]	-4	hSpCas9	negative selection	5755842
45008825	45008848	2	-	27260156	A673	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.6977754737890585	[325]	[243,203,258,259]	-9	hSpCas9	negative selection	5755843
45008762	45008785	2	+	27260156	A375	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.2244875743853889	[87]	[115,138,65,156]	3	hSpCas9	negative selection	5812838
45008639	45008662	2	-	27260156	A375	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.4290508192625896	[280]	[161,237,201,356]	-5	hSpCas9	negative selection	5812839
45006372	45006395	2	+	27260156	A375	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.2171160768628838	[303]	[291,459,211,280]	-3	hSpCas9	negative selection	5812840
45006438	45006461	2	-	27260156	A375	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.2595861750089624	[380]	[407,821,477,467]	4	hSpCas9	negative selection	5877092
45009072	45009095	2	+	27260156	A375	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.34764878651663855	[493]	[485,671,428,276]	-5	hSpCas9	negative selection	5877093
45008825	45008848	2	-	27260156	A375	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.5549659035760093	[325]	[320,316,209,202]	-6	hSpCas9	negative selection	5877094
45008762	45008785	2	+	27260156	COLO741	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.8172695041090186	[87]	[41,62,82]	-9	hSpCas9	negative selection	5934089
45008639	45008662	2	-	27260156	COLO741	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.14089723070245386	[280]	[430,367,390]	3	hSpCas9	negative selection	5934090
45006372	45006395	2	+	27260156	COLO741	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.0673997042567892	[303]	[379,374,357]	-1	hSpCas9	negative selection	5934091
45006438	45006461	2	-	27260156	COLO741	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.11567434001317126	[380]	[704,504,395]	2	hSpCas9	negative selection	5998343
45009072	45009095	2	+	27260156	COLO741	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.397126965493504	[493]	[536,388,512]	-7	hSpCas9	negative selection	5998344
45008825	45008848	2	-	27260156	COLO741	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.3724359821073734	[325]	[380,315,275]	-7	hSpCas9	negative selection	5998345
45008762	45008785	2	+	27260156	CAL120	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.5489209921270448	[87]	[170,196,114]	7	hSpCas9	negative selection	6055340
45008639	45008662	2	-	27260156	CAL120	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.13917209794475105	[280]	[302,412,425]	2	hSpCas9	negative selection	6055341
45006372	45006395	2	+	27260156	CAL120	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.17357474719527283	[303]	[388,506,378]	2	hSpCas9	negative selection	6055342
45006438	45006461	2	-	27260156	CAL120	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	-0.09461659278131507	[380]	[623,405,330]	-1	hSpCas9	negative selection	6119594
45009072	45009095	2	+	27260156	CAL120	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.5396629564785201	[493]	[509,370,400]	-6	hSpCas9	negative selection	6119595
45008825	45008848	2	-	27260156	CAL120	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.9194093331654201	[325]	[187,270,180]	-8	hSpCas9	negative selection	6119596
45008762	45008785	2	+	27260156	CADOES1	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.17121611114369895	[87]	[107,81,100,76]	3	hSpCas9	negative selection	6176591
45008639	45008662	2	-	27260156	CADOES1	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.2814358298395031	[280]	[174,181,214,290]	-5	hSpCas9	negative selection	6176592
45006372	45006395	2	+	27260156	CADOES1	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.22745780437582952	[303]	[160,220,243,343]	-4	hSpCas9	negative selection	6176593
45006438	45006461	2	-	27260156	CADOES1	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.20559501904552785	[380]	[338,466,414,413]	3	hSpCas9	negative selection	6240845
45009072	45009095	2	+	27260156	CADOES1	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.5204337819313741	[493]	[303,433,236,305]	-7	hSpCas9	negative selection	6240846
45008825	45008848	2	-	27260156	CADOES1	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.5731753793532253	[325]	[146,137,329,199]	-7	hSpCas9	negative selection	6240847
45008762	45008785	2	+	27260156	EWS502	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.1814060692779269	[87]	[128,56,95,141]	3	hSpCas9	negative selection	6297842
45008639	45008662	2	-	27260156	EWS502	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.10265698655898359	[280]	[294,319,271,397]	1	hSpCas9	negative selection	6297843
45006372	45006395	2	+	27260156	EWS502	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.011204177315708663	[303]	[235,352,334,364]	0	hSpCas9	negative selection	6297844
45006438	45006461	2	-	27260156	EWS502	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.5117956287768521	[380]	[440,692,636,537]	8	hSpCas9	negative selection	6362096
45009072	45009095	2	+	27260156	EWS502	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.06389142757099373	[493]	[429,588,566,413]	-1	hSpCas9	negative selection	6362097
45008825	45008848	2	-	27260156	EWS502	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.8278123008989653	[325]	[139,206,244,191]	-8	hSpCas9	negative selection	6362098
45008762	45008785	2	+	27260156	EW8	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.1596164496917556	[87]	[141,50,44,92]	3	hSpCas9	negative selection	6419093
45008639	45008662	2	-	27260156	EW8	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.06356009605894142	[280]	[469,138,247,117]	1	hSpCas9	negative selection	6419094
45006372	45006395	2	+	27260156	EW8	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.3672102624272946	[303]	[213,162,219,163]	-6	hSpCas9	negative selection	6419095
45006438	45006461	2	-	27260156	EW8	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.028516199419050314	[380]	[281,347,244,391]	0	hSpCas9	negative selection	6483347
45009072	45009095	2	+	27260156	EW8	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.413590934164961	[493]	[257,388,235,324]	-6	hSpCas9	negative selection	6483348
45008825	45008848	2	-	27260156	EW8	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.3491451519846145	[325]	[271,222,197,144]	-6	hSpCas9	negative selection	6483349
45008762	45008785	2	+	27260156	CORL105	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.3050569387093236	[87]	[135,170,128,72]	5	hSpCas9	negative selection	6540344
45008639	45008662	2	-	27260156	CORL105	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.007437949176136938	[280]	[323,225,405,366]	0	hSpCas9	negative selection	6540345
45006372	45006395	2	+	27260156	CORL105	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.07180467082504816	[303]	[224,405,407,320]	-1	hSpCas9	negative selection	6540346
45006438	45006461	2	-	27260156	CORL105	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.3413528939014868	[380]	[478,544,663,584]	6	hSpCas9	negative selection	6604598
45009072	45009095	2	+	27260156	CORL105	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.6782857446713991	[493]	[347,308,387,404]	-8	hSpCas9	negative selection	6604599
45008825	45008848	2	-	27260156	CORL105	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.30033757027411845	[325]	[215,314,466,262]	-5	hSpCas9	negative selection	6604600
45008762	45008785	2	+	27260156	HS294T	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.14230229802977545	[87]	[68,15,28,32]	2	hSpCas9	negative selection	6661595
45008639	45008662	2	-	27260156	HS294T	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.47774980059069405	[280]	[61,88,73,89]	-6	hSpCas9	negative selection	6661596
45006372	45006395	2	+	27260156	HS294T	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.1819934973251187	[303]	[82,102,183,175]	2	hSpCas9	negative selection	6661597
45006438	45006461	2	-	27260156	HS294T	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.15274603718918808	[380]	[123,214,151,165]	2	hSpCas9	negative selection	6725849
45009072	45009095	2	+	27260156	HS294T	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.583905429387535	[493]	[114,110,137,150]	-7	hSpCas9	negative selection	6725850
45008825	45008848	2	-	27260156	HS294T	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.22220850620635046	[325]	[78,64,184,106]	-3	hSpCas9	negative selection	6725851
45008762	45008785	2	+	27260156	HCC44	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.3998411073894115	[87]	[99,181,120,109]	6	hSpCas9	negative selection	6782846
45008639	45008662	2	-	27260156	HCC44	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.13763713427755797	[280]	[161,187,606,254]	-2	hSpCas9	negative selection	6782847
45006372	45006395	2	+	27260156	HCC44	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.014083759063021284	[303]	[344,315,398,313]	0	hSpCas9	negative selection	6782848
45006438	45006461	2	-	27260156	HCC44	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.1764290040958466	[380]	[701,339,609,357]	3	hSpCas9	negative selection	6847100
45009072	45009095	2	+	27260156	HCC44	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.5896867759279557	[493]	[590,258,403,272]	-7	hSpCas9	negative selection	6847101
45008825	45008848	2	-	27260156	HCC44	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.5371773917393547	[325]	[110,207,334,363]	-7	hSpCas9	negative selection	6847102
45008762	45008785	2	+	27260156	G402	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.19926412885860278	[87]	[127,59,100,196]	2	hSpCas9	negative selection	6904097
45008639	45008662	2	-	27260156	G402	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.10254152120253712	[280]	[532,337,292,330]	1	hSpCas9	negative selection	6904098
45006372	45006395	2	+	27260156	G402	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.9338207042179323	[303]	[83,377,77,228]	-8	hSpCas9	negative selection	6904099
45006438	45006461	2	-	27260156	G402	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.2996666866917523	[380]	[669,658,492,487]	4	hSpCas9	negative selection	6968351
45009072	45009095	2	+	27260156	G402	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.4372794040677898	[493]	[665,477,440,237]	-5	hSpCas9	negative selection	6968352
45008825	45008848	2	-	27260156	G402	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-1.0828291414455562	[325]	[49,195,338,147]	-8	hSpCas9	negative selection	6968353
45008762	45008785	2	+	27260156	L33	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.20707595862487072	[87]	[44,33,56,86]	-5	hSpCas9	negative selection	7025348
45008639	45008662	2	-	27260156	L33	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.2784995512499674	[280]	[291,94,132,189]	-6	hSpCas9	negative selection	7025349
45006372	45006395	2	+	27260156	L33	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.24386415983975407	[303]	[285,89,171,246]	-5	hSpCas9	negative selection	7025350
45006438	45006461	2	-	27260156	L33	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.23148108394570488	[380]	[482,185,290,388]	5	hSpCas9	negative selection	7089602
45009072	45009095	2	+	27260156	L33	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.23294507557739463	[493]	[351,127,342,472]	-5	hSpCas9	negative selection	7089603
45008825	45008848	2	-	27260156	L33	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.5665146329995587	[325]	[164,111,114,259]	-8	hSpCas9	negative selection	7089604
45008762	45008785	2	+	27260156	K562	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.32535336351939037	[87]	[64,113,110,98]	4	hSpCas9	negative selection	7146599
45008639	45008662	2	-	27260156	K562	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.8208916642441896	[280]	[136,244,590,718]	9	hSpCas9	negative selection	7146600
45006372	45006395	2	+	27260156	K562	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.2743722097346354	[303]	[146,147,446,147]	-3	hSpCas9	negative selection	7146601
45006438	45006461	2	-	27260156	K562	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.6538558247179658	[380]	[400,971,383,396]	8	hSpCas9	negative selection	7210853
45009072	45009095	2	+	27260156	K562	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.2272292575424228	[493]	[319,232,702,243]	-3	hSpCas9	negative selection	7210854
45008825	45008848	2	-	27260156	K562	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.2582456213315102	[325]	[566,74,247,109]	-3	hSpCas9	negative selection	7210855
45008762	45008785	2	+	27260156	HT29	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.36447211100918864	[87]	[116,147,144,138]	7	hSpCas9	negative selection	7267850
45008639	45008662	2	-	27260156	HT29	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.048384362415530346	[280]	[444,268,412,290]	0	hSpCas9	negative selection	7267851
45006372	45006395	2	+	27260156	HT29	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.15993338065044949	[303]	[451,457,454,303]	3	hSpCas9	negative selection	7267852
45006438	45006461	2	-	27260156	HT29	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.33729821250921427	[380]	[716,621,545,477]	6	hSpCas9	negative selection	7332104
45009072	45009095	2	+	27260156	HT29	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.051142252522527826	[493]	[529,661,577,550]	-1	hSpCas9	negative selection	7332105
45008825	45008848	2	-	27260156	HT29	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.45004187066985946	[325]	[354,226,376,208]	-7	hSpCas9	negative selection	7332106
45008762	45008785	2	+	27260156	MHHES1	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.16151527204281013	[87]	[67,157,48,82]	-3	hSpCas9	negative selection	7389101
45008639	45008662	2	-	27260156	MHHES1	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.1621354956462504	[280]	[292,409,341,359]	3	hSpCas9	negative selection	7389102
45006372	45006395	2	+	27260156	MHHES1	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.1628712726079764	[303]	[372,292,368,210]	-3	hSpCas9	negative selection	7389103
45006438	45006461	2	-	27260156	MHHES1	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.361684718413517	[380]	[579,794,509,376]	6	hSpCas9	negative selection	7453355
45009072	45009095	2	+	27260156	MHHES1	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.38307517137642655	[493]	[533,461,409,329]	-6	hSpCas9	negative selection	7453356
45008825	45008848	2	-	27260156	MHHES1	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.8748871581191686	[325]	[240,206,160,193]	-9	hSpCas9	negative selection	7453357
45008762	45008785	2	+	27260156	MEWO	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.4943610864903385	[87]	[117,28,39]	-8	hSpCas9	negative selection	7510352
45008639	45008662	2	-	27260156	MEWO	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.15453339874303262	[280]	[272,288,311]	3	hSpCas9	negative selection	7510353
45006372	45006395	2	+	27260156	MEWO	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.21975913908139122	[303]	[254,184,294]	-5	hSpCas9	negative selection	7510354
45006438	45006461	2	-	27260156	MEWO	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.47683434470654323	[380]	[407,500,561]	8	hSpCas9	negative selection	7574606
45009072	45009095	2	+	27260156	MEWO	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.32304531076005044	[493]	[552,332,257]	-6	hSpCas9	negative selection	7574607
45008825	45008848	2	-	27260156	MEWO	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.47529414314462315	[325]	[223,220,213]	-7	hSpCas9	negative selection	7574608
45008762	45008785	2	+	27260156	LNCAPCLONEFGC	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.6457766010708901	[87]	[140,141,81,125]	8	hSpCas9	negative selection	7631603
45008639	45008662	2	-	27260156	LNCAPCLONEFGC	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.15057057896175108	[280]	[152,286,307,387]	2	hSpCas9	negative selection	7631604
45006372	45006395	2	+	27260156	LNCAPCLONEFGC	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.28272661299881446	[303]	[245,379,344,368]	4	hSpCas9	negative selection	7631605
45006438	45006461	2	-	27260156	LNCAPCLONEFGC	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.3622935806284756	[380]	[412,433,567,378]	6	hSpCas9	negative selection	7695857
45009072	45009095	2	+	27260156	LNCAPCLONEFGC	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.2537913626837997	[493]	[328,371,495,322]	-4	hSpCas9	negative selection	7695858
45008825	45008848	2	-	27260156	LNCAPCLONEFGC	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.8565810044241329	[325]	[175,192,189,94]	-8	hSpCas9	negative selection	7695859
45008762	45008785	2	+	27260156	PANC0327	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.5933560705905652	[87]	[251,38,145,55]	8	hSpCas9	negative selection	7752854
45008639	45008662	2	-	27260156	PANC0327	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.02450504421532207	[280]	[440,90,317,201]	0	hSpCas9	negative selection	7752855
45006372	45006395	2	+	27260156	PANC0327	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.08007679900279996	[303]	[213,428,218,133]	-1	hSpCas9	negative selection	7752856
45006438	45006461	2	-	27260156	PANC0327	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.19833655730704264	[380]	[232,469,445,380]	3	hSpCas9	negative selection	7817108
45009072	45009095	2	+	27260156	PANC0327	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.6652039902274742	[493]	[435,282,209,189]	-7	hSpCas9	negative selection	7817109
45008825	45008848	2	-	27260156	PANC0327	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.516347881428787	[325]	[163,269,225,137]	-6	hSpCas9	negative selection	7817110
45008762	45008785	2	+	27260156	NCIH2009	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.5161642489801239	[87]	[67,114,323]	7	hSpCas9	negative selection	7874105
45008639	45008662	2	-	27260156	NCIH2009	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.47162227210156493	[280]	[228,293,314]	-6	hSpCas9	negative selection	7874106
45006372	45006395	2	+	27260156	NCIH2009	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.5032642604877979	[303]	[443,353,127]	-6	hSpCas9	negative selection	7874107
45006438	45006461	2	-	27260156	NCIH2009	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.01316818427539107	[380]	[532,528,547]	0	hSpCas9	negative selection	7938359
45009072	45009095	2	+	27260156	NCIH2009	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.6585333908492829	[493]	[588,437,313]	-7	hSpCas9	negative selection	7938360
45008825	45008848	2	-	27260156	NCIH2009	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.759130864545835	[325]	[362,293,167]	-7	hSpCas9	negative selection	7938361
45008762	45008785	2	+	27260156	NCIH1373	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.03877902403848754	[87]	[21,66,160,32]	0	hSpCas9	negative selection	7995356
45008639	45008662	2	-	27260156	NCIH1373	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-1.509811189131383	[280]	[168,70,104,28]	-9	hSpCas9	negative selection	7995357
45006372	45006395	2	+	27260156	NCIH1373	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.6326733235568844	[303]	[293,157,282,40]	-6	hSpCas9	negative selection	7995358
45006438	45006461	2	-	27260156	NCIH1373	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.3455849394359881	[380]	[574,434,477,185]	3	hSpCas9	negative selection	8059610
45009072	45009095	2	+	27260156	NCIH1373	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.7239724231616038	[493]	[566,224,289,79]	-6	hSpCas9	negative selection	8059611
45008825	45008848	2	-	27260156	NCIH1373	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-2.341147227928727	[325]	[88,91,42,16]	-9	hSpCas9	negative selection	8059612
45008762	45008785	2	+	27260156	PATU8902	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.8418788207042822	[87]	[31,161,81,695]	8	hSpCas9	negative selection	8116607
45008639	45008662	2	-	27260156	PATU8902	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.024881698307052003	[280]	[174,585,261,569]	0	hSpCas9	negative selection	8116608
45006372	45006395	2	+	27260156	PATU8902	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.3318633877716307	[303]	[381,419,202,376]	-3	hSpCas9	negative selection	8116609
45006438	45006461	2	-	27260156	PATU8902	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.20370795387770096	[380]	[588,972,374,558]	2	hSpCas9	negative selection	8180861
45009072	45009095	2	+	27260156	PATU8902	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.09473233288028678	[493]	[735,651,645,946]	0	hSpCas9	negative selection	8180862
45008825	45008848	2	-	27260156	PATU8902	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.9283490905690446	[325]	[223,93,220,441]	-7	hSpCas9	negative selection	8180863
45008762	45008785	2	+	27260156	PANC1	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.23685565801891695	[87]	[109,185,31,51]	4	hSpCas9	negative selection	8237858
45008639	45008662	2	-	27260156	PANC1	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.18329728830783443	[280]	[255,250,199,155]	-3	hSpCas9	negative selection	8237859
45006372	45006395	2	+	27260156	PANC1	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.1379697618021628	[303]	[149,357,240,224]	-2	hSpCas9	negative selection	8237860
45006438	45006461	2	-	27260156	PANC1	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	-0.12035502712179569	[380]	[319,425,292,201]	-2	hSpCas9	negative selection	8302112
45009072	45009095	2	+	27260156	PANC1	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.25536008404751237	[493]	[328,376,326,382]	-4	hSpCas9	negative selection	8302113
45008825	45008848	2	-	27260156	PANC1	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.4822336169097079	[325]	[131,274,271,145]	-6	hSpCas9	negative selection	8302114
45008762	45008785	2	+	27260156	PANC0813	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	-0.3041798851477151	[87]	[110,33,135,57]	-5	hSpCas9	negative selection	8359109
45008639	45008662	2	-	27260156	PANC0813	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.4552722233047436	[280]	[312,201,244,210]	-6	hSpCas9	negative selection	8359110
45006372	45006395	2	+	27260156	PANC0813	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.17365311622315038	[303]	[506,189,473,446]	3	hSpCas9	negative selection	8359111
45006438	45006461	2	-	27260156	PANC0813	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.41472640209119277	[380]	[673,624,478,612]	6	hSpCas9	negative selection	8423363
45009072	45009095	2	+	27260156	PANC0813	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.39614669609924413	[493]	[447,399,459,454]	-6	hSpCas9	negative selection	8423364
45008825	45008848	2	-	27260156	PANC0813	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.8748152190736931	[325]	[208,209,207,207]	-8	hSpCas9	negative selection	8423365
45008762	45008785	2	+	27260156	RDES	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.42270011354816583	[87]	[114,168,94,162]	6	hSpCas9	negative selection	8480360
45008639	45008662	2	-	27260156	RDES	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.24024048080169835	[280]	[291,292,211,279]	-4	hSpCas9	negative selection	8480361
45006372	45006395	2	+	27260156	RDES	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.5314238154040962	[303]	[191,200,285,307]	-7	hSpCas9	negative selection	8480362
45006438	45006461	2	-	27260156	RDES	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	-0.1293260847133872	[380]	[286,376,367,617]	-2	hSpCas9	negative selection	8544614
45009072	45009095	2	+	27260156	RDES	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.7701267184175825	[493]	[272,300,422,346]	-8	hSpCas9	negative selection	8544615
45008825	45008848	2	-	27260156	RDES	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.8566148529631148	[325]	[171,199,235,225]	-8	hSpCas9	negative selection	8544616
45008762	45008785	2	+	27260156	PC3	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.3268814937874609	[87]	[35,99,208,162]	7	hSpCas9	negative selection	8601611
45008639	45008662	2	-	27260156	PC3	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.09454310552225853	[280]	[198,268,613,249]	2	hSpCas9	negative selection	8601612
45006372	45006395	2	+	27260156	PC3	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.19517947704103134	[303]	[158,254,512,249]	-4	hSpCas9	negative selection	8601613
45006438	45006461	2	-	27260156	PC3	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.1242827778529961	[380]	[228,424,555,550]	3	hSpCas9	negative selection	8665865
45009072	45009095	2	+	27260156	PC3	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.8741780403683691	[493]	[110,292,466,332]	-9	hSpCas9	negative selection	8665866
45008825	45008848	2	-	27260156	PC3	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.7659803784944226	[325]	[103,149,318,268]	-9	hSpCas9	negative selection	8665867
45008762	45008785	2	+	27260156	PATU8988T	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.6526382986024621	[87]	[48,260,83,154]	9	hSpCas9	negative selection	8722862
45008639	45008662	2	-	27260156	PATU8988T	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.2734500267262217	[280]	[328,355,318,309]	5	hSpCas9	negative selection	8722863
45006372	45006395	2	+	27260156	PATU8988T	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.27377231874786184	[303]	[381,351,404,273]	5	hSpCas9	negative selection	8722864
45006438	45006461	2	-	27260156	PATU8988T	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.16725861371684692	[380]	[344,593,375,350]	3	hSpCas9	negative selection	8787116
45009072	45009095	2	+	27260156	PATU8988T	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.35121594698095665	[493]	[277,325,485,402]	-5	hSpCas9	negative selection	8787117
45008825	45008848	2	-	27260156	PATU8988T	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.6120860614662786	[325]	[66,161,223,380]	-7	hSpCas9	negative selection	8787118
45008762	45008785	2	+	27260156	T47D	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.1179561743232167	[87]	[154,62,83,148]	2	hSpCas9	negative selection	8844113
45008639	45008662	2	-	27260156	T47D	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.22031348855496047	[280]	[225,238,293,370]	-5	hSpCas9	negative selection	8844114
45006372	45006395	2	+	27260156	T47D	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.2613165735897067	[303]	[261,263,328,329]	-5	hSpCas9	negative selection	8844115
45006438	45006461	2	-	27260156	T47D	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.23230875459309425	[380]	[504,488,559,533]	5	hSpCas9	negative selection	8908367
45009072	45009095	2	+	27260156	T47D	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.3545718766570599	[493]	[484,370,469,481]	-6	hSpCas9	negative selection	8908368
45008825	45008848	2	-	27260156	T47D	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.43200069295446	[325]	[315,207,321,285]	-7	hSpCas9	negative selection	8908369
45008762	45008785	2	+	27260156	SU8686	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.7729751747886386	[87]	[75,263,154,82]	9	hSpCas9	negative selection	8965364
45008639	45008662	2	-	27260156	SU8686	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.30218529472863487	[280]	[121,238,328,224]	-5	hSpCas9	negative selection	8965365
45006372	45006395	2	+	27260156	SU8686	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.3302225853691323	[303]	[241,208,169,356]	-5	hSpCas9	negative selection	8965366
45006438	45006461	2	-	27260156	SU8686	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.3039190220087068	[380]	[434,393,532,523]	5	hSpCas9	negative selection	9029618
45009072	45009095	2	+	27260156	SU8686	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.18326926934938187	[493]	[426,369,383,570]	-3	hSpCas9	negative selection	9029619
45008825	45008848	2	-	27260156	SU8686	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.681189627588275	[325]	[241,171,197,189]	-7	hSpCas9	negative selection	9029620
45008762	45008785	2	+	27260156	SKES1	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.020915914616241427	[87]	[140,56,72,87]	0	hSpCas9	negative selection	9086615
45008639	45008662	2	-	27260156	SKES1	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.08832517056414535	[280]	[342,272,257,197]	-2	hSpCas9	negative selection	9086616
45006372	45006395	2	+	27260156	SKES1	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.23160603246167477	[303]	[329,278,260,181]	-5	hSpCas9	negative selection	9086617
45006438	45006461	2	-	27260156	SKES1	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.08778314222989103	[380]	[576,442,337,295]	2	hSpCas9	negative selection	9150869
45009072	45009095	2	+	27260156	SKES1	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.35936791007725455	[493]	[437,409,384,317]	-7	hSpCas9	negative selection	9150870
45008825	45008848	2	-	27260156	SKES1	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.5873926457683201	[325]	[196,232,291,147]	-8	hSpCas9	negative selection	9150871
45008762	45008785	2	+	27260156	TOV112D	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.20876585004866888	[87]	[125,120,100,66]	4	hSpCas9	negative selection	9207866
45008639	45008662	2	-	27260156	TOV112D	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.42031953273906664	[280]	[197,294,168,198]	-7	hSpCas9	negative selection	9207867
45006372	45006395	2	+	27260156	TOV112D	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.20544982711852322	[303]	[323,373,201,189]	-4	hSpCas9	negative selection	9207868
45006438	45006461	2	-	27260156	TOV112D	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.23228542010086362	[380]	[320,496,434,537]	4	hSpCas9	negative selection	9272120
45009072	45009095	2	+	27260156	TOV112D	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.12704677203467385	[493]	[536,419,348,502]	-2	hSpCas9	negative selection	9272121
45008825	45008848	2	-	27260156	TOV112D	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.5205133843906906	[325]	[174,392,282,98]	-8	hSpCas9	negative selection	9272122
45008762	45008785	2	+	27260156	TC71	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.11309742638388753	[87]	[94,98,120,91]	3	hSpCas9	negative selection	9329117
45008639	45008662	2	-	27260156	TC71	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	-0.09446127204082855	[280]	[289,284,267,285]	-2	hSpCas9	negative selection	9329118
45006372	45006395	2	+	27260156	TC71	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	0.06410770650489428	[303]	[268,344,288,470]	1	hSpCas9	negative selection	9329119
45006438	45006461	2	-	27260156	TC71	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.1358467301725988	[380]	[487,547,357,399]	3	hSpCas9	negative selection	9393371
45009072	45009095	2	+	27260156	TC71	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.2587434210446346	[493]	[491,466,415,391]	-6	hSpCas9	negative selection	9393372
45008825	45008848	2	-	27260156	TC71	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.40968413753768407	[325]	[229,244,226,357]	-8	hSpCas9	negative selection	9393373
45008762	45008785	2	+	27260156	TC32	viability	GCGGGAATTTGCGGCGCACGCGG	SIX2	ENSG00000170577	0.10620868629536018	[87]	[72,61,118,115]	2	hSpCas9	negative selection	9450368
45008639	45008662	2	-	27260156	TC32	viability	ACCCCGCGAGAAGCGTGAGCTGG	SIX2	ENSG00000170577	0.27608494463537997	[280]	[260,322,383,306]	5	hSpCas9	negative selection	9450369
45006372	45006395	2	+	27260156	TC32	viability	GAGTGGTCTGGCGTCCCCGATGG	SIX2	ENSG00000170577	-0.035169565592368834	[303]	[277,200,442,231]	0	hSpCas9	negative selection	9450370
45006438	45006461	2	-	27260156	TC32	viability	AACAGCCACAACCCGCTGAATGG	SIX2	ENSG00000170577	0.2685056166723764	[380]	[504,309,477,450]	5	hSpCas9	negative selection	9514622
45009072	45009095	2	+	27260156	TC32	viability	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.3440794351553476	[493]	[380,298,371,414]	-6	hSpCas9	negative selection	9514623
45008825	45008848	2	-	27260156	TC32	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.7023684942456494	[325]	[153,76,378,214]	-8	hSpCas9	negative selection	9514624
45006211	45006234	2	+	27869803	HPAFII	viability after 27 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-2.184928689907362	[102]	[0,20,NaN]	-8	hSpCas9	negative selection	9575114
45006427	45006450	2	+	27869803	HPAFII	viability after 27 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	-0.9819356106396384	[124]	[47,20,NaN]	-6	hSpCas9	negative selection	9575115
45008825	45008848	2	-	27869803	HPAFII	viability after 27 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.17237474955403764	[401]	[240,142,NaN]	-1	hSpCas9	negative selection	9575116
45009024	45009047	2	-	27869803	HPAFII	viability after 27 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.38552091521524745	[255]	[249,113,NaN]	3	hSpCas9	negative selection	9575117
45009072	45009095	2	+	27869803	HPAFII	viability after 27 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.13335858991399435	[168]	[121,76,NaN]	1	hSpCas9	negative selection	9575118
45006211	45006234	2	+	27869803	HPAFII	viability after 15 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-3.5603652396764436	[102]	[9,8,NaN]	-9	hSpCas9	negative selection	9657563
45006427	45006450	2	+	27869803	HPAFII	viability after 15 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	-0.5706451568626121	[124]	[132,63,NaN]	-6	hSpCas9	negative selection	9657564
45008825	45008848	2	-	27869803	HPAFII	viability after 15 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.35905667558340454	[401]	[527,217,NaN]	-4	hSpCas9	negative selection	9657565
45009024	45009047	2	-	27869803	HPAFII	viability after 15 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.07127769559227352	[255]	[449,188,NaN]	0	hSpCas9	negative selection	9657566
45009072	45009095	2	+	27869803	HPAFII	viability after 15 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.56211971654213	[168]	[417,174,NaN]	6	hSpCas9	negative selection	9657567
45006211	45006234	2	+	27869803	ASPC1	viability after 36 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-1.1560676377162606	[217]	[71,41,0]	-8	hSpCas9	negative selection	9740012
45006427	45006450	2	+	27869803	ASPC1	viability after 36 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	1.4501991167803423	[274]	[548,122,168]	9	hSpCas9	negative selection	9740013
45008825	45008848	2	-	27869803	ASPC1	viability after 36 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	1.2185515213354907	[898]	[1279,631,414]	9	hSpCas9	negative selection	9740014
45009024	45009047	2	-	27869803	ASPC1	viability after 36 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.10967585014831044	[814]	[716,102,177]	1	hSpCas9	negative selection	9740015
45009072	45009095	2	+	27869803	ASPC1	viability after 36 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.8771296705656229	[491]	[412,144,378]	8	hSpCas9	negative selection	9740016
45006211	45006234	2	+	27869803	PATU8988S	viability after 35 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-0.19124023416527702	[223]	[85,71,NaN]	-2	hSpCas9	negative selection	9822461
45006427	45006450	2	+	27869803	PATU8988S	viability after 35 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.14994401710564453	[289]	[168,89,NaN]	1	hSpCas9	negative selection	9822462
45008825	45008848	2	-	27869803	PATU8988S	viability after 35 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.02439305396776581	[808]	[259,380,NaN]	0	hSpCas9	negative selection	9822463
45009024	45009047	2	-	27869803	PATU8988S	viability after 35 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	-0.25843893405317697	[566]	[149,231,NaN]	-3	hSpCas9	negative selection	9822464
45009072	45009095	2	+	27869803	PATU8988S	viability after 35 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.3728342904796217	[281]	[176,116,NaN]	4	hSpCas9	negative selection	9822465
45006211	45006234	2	+	27869803	PATU8988S	viability after 31 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	0.06266145966283077	[223]	[109,71,NaN]	0	hSpCas9	negative selection	9904910
45006427	45006450	2	+	27869803	PATU8988S	viability after 31 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	0.12477241294749886	[289]	[133,115,NaN]	1	hSpCas9	negative selection	9904911
45008825	45008848	2	-	27869803	PATU8988S	viability after 31 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.054094466151984766	[808]	[271,359,NaN]	0	hSpCas9	negative selection	9904912
45009024	45009047	2	-	27869803	PATU8988S	viability after 31 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.04367304035699192	[566]	[214,255,NaN]	0	hSpCas9	negative selection	9904913
45009072	45009095	2	+	27869803	PATU8988S	viability after 31 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	0.3838482753967043	[281]	[151,139,NaN]	5	hSpCas9	negative selection	9904914
45006211	45006234	2	+	27869803	HPAFII	viability after 35 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-5.704411974186543	[102]	[0,0,NaN]	-9	hSpCas9	negative selection	9987359
45006427	45006450	2	+	27869803	HPAFII	viability after 35 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	-0.4003973763518496	[124]	[54,39,NaN]	-2	hSpCas9	negative selection	9987360
45008825	45008848	2	-	27869803	HPAFII	viability after 35 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-1.1349640542683808	[401]	[134,44,NaN]	-6	hSpCas9	negative selection	9987361
45009024	45009047	2	-	27869803	HPAFII	viability after 35 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.5791179460562407	[255]	[123,271,NaN]	4	hSpCas9	negative selection	9987362
45009072	45009095	2	+	27869803	HPAFII	viability after 35 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.8749184785860001	[168]	[56,34,NaN]	-5	hSpCas9	negative selection	9987363
45006211	45006234	2	+	27869803	HPAFII	viability after 31 days	GGATGGAGTCCTGCAGGCCATGG	SIX2	ENSG00000170577	-2.26730833521676	[102]	[0,23,NaN]	-8	hSpCas9	negative selection	10069808
45006427	45006450	2	+	27869803	HPAFII	viability after 31 days	ACTTGCCGCTGCCATTCAGCGGG	SIX2	ENSG00000170577	-0.937515555313055	[124]	[5,69,NaN]	-5	hSpCas9	negative selection	10069809
45008825	45008848	2	-	27869803	HPAFII	viability after 31 days	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.6361377461956234	[401]	[159,128,NaN]	-4	hSpCas9	negative selection	10069810
45009024	45009047	2	-	27869803	HPAFII	viability after 31 days	AGCAGGGCGGCAACATCGAGCGG	SIX2	ENSG00000170577	0.2619706550505606	[255]	[144,201,NaN]	1	hSpCas9	negative selection	10069811
45009072	45009095	2	+	27869803	HPAFII	viability after 31 days	TTGCTCCTGCGTGAAGCCGAAGG	SIX2	ENSG00000170577	-0.4349901463565836	[168]	[95,41,NaN]	-3	hSpCas9	negative selection	10069812
45009090	45009113	2	+	28162770	P31FUJ	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	-0.20214165171258325	[418]	[427]	-2	hSpCas9	negative selection	10234566
45008598	45008621	2	+	28162770	P31FUJ	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	-0.5231685922193678	[372]	[304]	-4	hSpCas9	negative selection	10234567
45008825	45008848	2	-	28162770	P31FUJ	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.1255689810893511	[323]	[348]	-1	hSpCas9	negative selection	10234568
45009037	45009060	2	-	28162770	P31FUJ	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	0.1752825342226983	[155]	[206]	1	hSpCas9	negative selection	10234569
45008976	45008999	2	+	28162770	P31FUJ	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.35216029630677737	[47]	[71]	4	hSpCas9	negative selection	10234570
45008942	45008965	2	-	28162770	P31FUJ	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.6847356353936485	[152]	[288]	7	hSpCas9	negative selection	10234571
45008929	45008952	2	-	28162770	P31FUJ	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.6915633577487703	[185]	[352]	7	hSpCas9	negative selection	10234572
45008852	45008875	2	+	28162770	P31FUJ	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	0.4497156057294511	[161]	[259]	5	hSpCas9	negative selection	10234573
45008775	45008798	2	+	28162770	P31FUJ	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	1.2301697719281672	[73]	[203]	9	hSpCas9	negative selection	10234574
45008633	45008656	2	-	28162770	P31FUJ	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.1534763018830415	[227]	[297]	1	hSpCas9	negative selection	10234575
45009090	45009113	2	+	28162770	TF1	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	NaN	[NaN]	[467]	1	hSpCas9	negative selection	10403932
45008598	45008621	2	+	28162770	TF1	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	NaN	[NaN]	[319]	1	hSpCas9	negative selection	10403933
45008825	45008848	2	-	28162770	TF1	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10403934
45009037	45009060	2	-	28162770	TF1	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10403935
45008976	45008999	2	+	28162770	TF1	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10403936
45008942	45008965	2	-	28162770	TF1	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10403937
45008929	45008952	2	-	28162770	TF1	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10403938
45008852	45008875	2	+	28162770	TF1	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	NaN	[NaN]	[168]	1	hSpCas9	negative selection	10403939
45008775	45008798	2	+	28162770	TF1	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10403940
45008633	45008656	2	-	28162770	TF1	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	NaN	[NaN]	[142]	1	hSpCas9	negative selection	10403941
45009090	45009113	2	+	28162770	SKM1	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.31901061150506793	[111]	[246]	3	hSpCas9	negative selection	10573298
45008598	45008621	2	+	28162770	SKM1	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	0.9369902024741995	[77]	[263]	8	hSpCas9	negative selection	10573299
45008825	45008848	2	-	28162770	SKM1	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.18973348252249256	[79]	[123]	-2	hSpCas9	negative selection	10573300
45009037	45009060	2	-	28162770	SKM1	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	0.8001937088981259	[50]	[156]	7	hSpCas9	negative selection	10573301
45008976	45008999	2	+	28162770	SKM1	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.6451243124052926	[16]	[46]	6	hSpCas9	negative selection	10573302
45008942	45008965	2	-	28162770	SKM1	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	-1.295932886354418	[74]	[53]	-7	hSpCas9	negative selection	10573303
45008929	45008952	2	-	28162770	SKM1	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.31550182572792945	[34]	[76]	3	hSpCas9	negative selection	10573304
45008852	45008875	2	+	28162770	SKM1	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	0.08178298671869133	[30]	[57]	0	hSpCas9	negative selection	10573305
45008775	45008798	2	+	28162770	SKM1	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	-0.2564045221677804	[24]	[36]	-2	hSpCas9	negative selection	10573306
45008633	45008656	2	-	28162770	SKM1	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	-0.26170125153511853	[58]	[86]	-2	hSpCas9	negative selection	10573307
45009090	45009113	2	+	28162770	SKM1	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.31901061150506793	[111]	[246]	3	hSpCas9	negative selection	10742664
45008598	45008621	2	+	28162770	SKM1	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	0.9369902024741995	[77]	[263]	8	hSpCas9	negative selection	10742665
45008825	45008848	2	-	28162770	SKM1	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.18973348252249256	[79]	[123]	-2	hSpCas9	negative selection	10742666
45009037	45009060	2	-	28162770	SKM1	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	0.8001937088981259	[50]	[156]	7	hSpCas9	negative selection	10742667
45008976	45008999	2	+	28162770	SKM1	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.6451243124052926	[16]	[46]	6	hSpCas9	negative selection	10742668
45008942	45008965	2	-	28162770	SKM1	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	-1.295932886354418	[74]	[53]	-7	hSpCas9	negative selection	10742669
45008929	45008952	2	-	28162770	SKM1	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.31550182572792945	[34]	[76]	3	hSpCas9	negative selection	10742670
45008852	45008875	2	+	28162770	SKM1	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	0.08178298671869133	[30]	[57]	0	hSpCas9	negative selection	10742671
45008775	45008798	2	+	28162770	SKM1	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	-0.2564045221677804	[24]	[36]	-2	hSpCas9	negative selection	10742672
45008633	45008656	2	-	28162770	SKM1	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	-0.26170125153511853	[58]	[86]	-2	hSpCas9	negative selection	10742673
45009090	45009113	2	+	28162770	PL21	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.23931021176999767	[435]	[223]	2	hSpCas9	negative selection	10912030
45008598	45008621	2	+	28162770	PL21	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	-1.1616287449298333	[256]	[49]	-7	hSpCas9	negative selection	10912031
45008825	45008848	2	-	28162770	PL21	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	1.115103510633521	[296]	[279]	8	hSpCas9	negative selection	10912032
45009037	45009060	2	-	28162770	PL21	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	0.34452952382449503	[189]	[104]	3	hSpCas9	negative selection	10912033
45008976	45008999	2	+	28162770	PL21	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	-5.192177808289441	[83]	[0]	-9	hSpCas9	negative selection	10912034
45008942	45008965	2	-	28162770	PL21	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	-0.2779076823153242	[155]	[55]	-2	hSpCas9	negative selection	10912035
45008929	45008952	2	-	28162770	PL21	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	-0.011364490704391494	[131]	[56]	0	hSpCas9	negative selection	10912036
45008852	45008875	2	+	28162770	PL21	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	-0.6021797176709855	[142]	[40]	-4	hSpCas9	negative selection	10912037
45008775	45008798	2	+	28162770	PL21	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	0.25672314285568754	[74]	[38]	2	hSpCas9	negative selection	10912038
45008633	45008656	2	-	28162770	PL21	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.8940364867636403	[135]	[109]	7	hSpCas9	negative selection	10912039
45009090	45009113	2	+	28162770	P31FUJ	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	-0.20214165171258325	[418]	[427]	-2	hSpCas9	negative selection	11081396
45008598	45008621	2	+	28162770	P31FUJ	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	-0.5231685922193678	[372]	[304]	-4	hSpCas9	negative selection	11081397
45008825	45008848	2	-	28162770	P31FUJ	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.1255689810893511	[323]	[348]	-1	hSpCas9	negative selection	11081398
45009037	45009060	2	-	28162770	P31FUJ	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	0.1752825342226983	[155]	[206]	1	hSpCas9	negative selection	11081399
45008976	45008999	2	+	28162770	P31FUJ	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.35216029630677737	[47]	[71]	4	hSpCas9	negative selection	11081400
45008942	45008965	2	-	28162770	P31FUJ	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.6847356353936485	[152]	[288]	7	hSpCas9	negative selection	11081401
45008929	45008952	2	-	28162770	P31FUJ	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.6915633577487703	[185]	[352]	7	hSpCas9	negative selection	11081402
45008852	45008875	2	+	28162770	P31FUJ	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	0.4497156057294511	[161]	[259]	5	hSpCas9	negative selection	11081403
45008775	45008798	2	+	28162770	P31FUJ	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	1.2301697719281672	[73]	[203]	9	hSpCas9	negative selection	11081404
45008633	45008656	2	-	28162770	P31FUJ	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.1534763018830415	[227]	[297]	1	hSpCas9	negative selection	11081405
45009090	45009113	2	+	28162770	OCIAML5	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.5903951893308541	[240]	[654]	5	hSpCas9	negative selection	11250762
45008598	45008621	2	+	28162770	OCIAML5	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	-0.02937110267190679	[146]	[259]	0	hSpCas9	negative selection	11250763
45008825	45008848	2	-	28162770	OCIAML5	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.6516998470091783	[133]	[379]	6	hSpCas9	negative selection	11250764
45009037	45009060	2	-	28162770	OCIAML5	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-0.28270092519385936	[123]	[183]	-2	hSpCas9	negative selection	11250765
45008976	45008999	2	+	28162770	OCIAML5	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	-0.38909459452145123	[36]	[50]	-3	hSpCas9	negative selection	11250766
45008942	45008965	2	-	28162770	OCIAML5	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.6890796975646697	[77]	[226]	6	hSpCas9	negative selection	11250767
45008929	45008952	2	-	28162770	OCIAML5	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	1.0859117025286185	[100]	[386]	8	hSpCas9	negative selection	11250768
45008852	45008875	2	+	28162770	OCIAML5	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	0.016021753630421964	[102]	[187]	0	hSpCas9	negative selection	11250769
45008775	45008798	2	+	28162770	OCIAML5	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	1.0162894233255322	[42]	[156]	8	hSpCas9	negative selection	11250770
45008633	45008656	2	-	28162770	OCIAML5	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.17978229517534278	[111]	[228]	1	hSpCas9	negative selection	11250771
45009090	45009113	2	+	28162770	EOL1	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.17580500962797507	[819]	[487]	1	hSpCas9	negative selection	11420128
45008598	45008621	2	+	28162770	EOL1	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	0.8963770988793739	[361]	[354]	7	hSpCas9	negative selection	11420129
45008825	45008848	2	-	28162770	EOL1	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.010539771092864969	[634]	[336]	0	hSpCas9	negative selection	11420130
45009037	45009060	2	-	28162770	EOL1	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	0.3844150523101578	[300]	[206]	3	hSpCas9	negative selection	11420131
45008976	45008999	2	+	28162770	EOL1	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.0978793744560964	[93]	[52]	0	hSpCas9	negative selection	11420132
45008942	45008965	2	-	28162770	EOL1	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.5656931076848146	[276]	[215]	5	hSpCas9	negative selection	11420133
45008929	45008952	2	-	28162770	EOL1	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.26424014593373624	[225]	[142]	2	hSpCas9	negative selection	11420134
45008852	45008875	2	+	28162770	EOL1	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	0.36304424367336746	[182]	[123]	3	hSpCas9	negative selection	11420135
45008775	45008798	2	+	28162770	EOL1	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	0.5095102722916907	[99]	[74]	4	hSpCas9	negative selection	11420136
45008633	45008656	2	-	28162770	EOL1	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.5160829262151767	[145]	[109]	4	hSpCas9	negative selection	11420137
45009090	45009113	2	+	28162770	MOLM13	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.5911921627363206	[593]	[646]	4	hSpCas9	negative selection	11589494
45008598	45008621	2	+	28162770	MOLM13	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	0.16774180269368555	[377]	[306]	1	hSpCas9	negative selection	11589495
45008825	45008848	2	-	28162770	MOLM13	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.5682209118647019	[444]	[216]	-3	hSpCas9	negative selection	11589496
45009037	45009060	2	-	28162770	MOLM13	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-1.4024753380388257	[233]	[63]	-6	hSpCas9	negative selection	11589497
45008976	45008999	2	+	28162770	MOLM13	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.9497583893016315	[57]	[80]	7	hSpCas9	negative selection	11589498
45008942	45008965	2	-	28162770	MOLM13	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.9165861921746539	[232]	[317]	7	hSpCas9	negative selection	11589499
45008929	45008952	2	-	28162770	MOLM13	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.9368437743003828	[150]	[208]	7	hSpCas9	negative selection	11589500
45008852	45008875	2	+	28162770	MOLM13	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	-0.017537445625663062	[174]	[124]	0	hSpCas9	negative selection	11589501
45008775	45008798	2	+	28162770	MOLM13	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	-0.9167744686907464	[93]	[35]	-5	hSpCas9	negative selection	11589502
45008633	45008656	2	-	28162770	MOLM13	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	-0.10346268765792438	[210]	[141]	0	hSpCas9	negative selection	11589503
45009090	45009113	2	+	28162770	HEL	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.9143770288258879	[612]	[739]	7	hSpCas9	negative selection	11758860
45008598	45008621	2	+	28162770	HEL	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	-0.932274008313194	[288]	[96]	-5	hSpCas9	negative selection	11758861
45008825	45008848	2	-	28162770	HEL	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.05022462624708168	[408]	[252]	0	hSpCas9	negative selection	11758862
45009037	45009060	2	-	28162770	HEL	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	0.2914772431548279	[235]	[184]	2	hSpCas9	negative selection	11758863
45008976	45008999	2	+	28162770	HEL	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.8420476402237637	[80]	[92]	7	hSpCas9	negative selection	11758864
45008942	45008965	2	-	28162770	HEL	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	1.1245293748488492	[226]	[316]	8	hSpCas9	negative selection	11758865
45008929	45008952	2	-	28162770	HEL	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.6517839716033639	[158]	[159]	5	hSpCas9	negative selection	11758866
45008852	45008875	2	+	28162770	HEL	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	-0.6437839267558066	[160]	[65]	-4	hSpCas9	negative selection	11758867
45008775	45008798	2	+	28162770	HEL	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	1.2801687526156484	[71]	[111]	9	hSpCas9	negative selection	11758868
45008633	45008656	2	-	28162770	HEL	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.6280173262935915	[196]	[194]	5	hSpCas9	negative selection	11758869
45009090	45009113	2	+	28162770	MV411	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.7799326316097959	[447]	[647]	7	hSpCas9	negative selection	11928226
45008598	45008621	2	+	28162770	MV411	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	-0.24035629093138258	[243]	[173]	-2	hSpCas9	negative selection	11928227
45008825	45008848	2	-	28162770	MV411	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	-0.11124909411470474	[317]	[247]	-1	hSpCas9	negative selection	11928228
45009037	45009060	2	-	28162770	MV411	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-0.5971079305832456	[166]	[92]	-4	hSpCas9	negative selection	11928229
45008976	45008999	2	+	28162770	MV411	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.5989099212841529	[57]	[73]	5	hSpCas9	negative selection	11928230
45008942	45008965	2	-	28162770	MV411	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.455242435896177	[141]	[163]	4	hSpCas9	negative selection	11928231
45008929	45008952	2	-	28162770	MV411	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.7536229381198143	[137]	[195]	6	hSpCas9	negative selection	11928232
45008852	45008875	2	+	28162770	MV411	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	0.9317503958695582	[172]	[277]	8	hSpCas9	negative selection	11928233
45008775	45008798	2	+	28162770	MV411	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	-0.2220477325184449	[71]	[51]	-2	hSpCas9	negative selection	11928234
45008633	45008656	2	-	28162770	MV411	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.753716701811453	[156]	[222]	6	hSpCas9	negative selection	11928235
45009090	45009113	2	+	28162770	MONOMAC1	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.7775778345205326	[257]	[506]	7	hSpCas9	negative selection	12097592
45008598	45008621	2	+	28162770	MONOMAC1	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	1.4301973064498497	[212]	[657]	9	hSpCas9	negative selection	12097593
45008825	45008848	2	-	28162770	MONOMAC1	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.764693136012729	[190]	[371]	7	hSpCas9	negative selection	12097594
45009037	45009060	2	-	28162770	MONOMAC1	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	0.3402289116303062	[81]	[118]	3	hSpCas9	negative selection	12097595
45008976	45008999	2	+	28162770	MONOMAC1	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.5082198873793143	[45]	[74]	5	hSpCas9	negative selection	12097596
45008942	45008965	2	-	28162770	MONOMAC1	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	1.3372995805916346	[86]	[251]	9	hSpCas9	negative selection	12097597
45008929	45008952	2	-	28162770	MONOMAC1	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.23705898803497466	[93]	[126]	2	hSpCas9	negative selection	12097598
45008852	45008875	2	+	28162770	MONOMAC1	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	0.4773872810379396	[98]	[157]	5	hSpCas9	negative selection	12097599
45008775	45008798	2	+	28162770	MONOMAC1	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	0.5399287471066523	[41]	[69]	5	hSpCas9	negative selection	12097600
45008633	45008656	2	-	28162770	MONOMAC1	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	1.0064965470255782	[65]	[151]	8	hSpCas9	negative selection	12097601
45009090	45009113	2	+	28162770	OCIAML2	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.22033402933588353	[93]	[606]	2	hSpCas9	negative selection	12266958
45008598	45008621	2	+	28162770	OCIAML2	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	0.15775495577012366	[59]	[370]	1	hSpCas9	negative selection	12266959
45008825	45008848	2	-	28162770	OCIAML2	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.5504317902856686	[50]	[413]	5	hSpCas9	negative selection	12266960
45009037	45009060	2	-	28162770	OCIAML2	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-0.011198206604863925	[25]	[142]	0	hSpCas9	negative selection	12266961
45008976	45008999	2	+	28162770	OCIAML2	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.7257673875613422	[11]	[109]	7	hSpCas9	negative selection	12266962
45008942	45008965	2	-	28162770	OCIAML2	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.9078817980115687	[29]	[311]	8	hSpCas9	negative selection	12266963
45008929	45008952	2	-	28162770	OCIAML2	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	0.7456880816846023	[16]	[157]	7	hSpCas9	negative selection	12266964
45008852	45008875	2	+	28162770	OCIAML2	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	0.9497019737061956	[16]	[181]	8	hSpCas9	negative selection	12266965
45008775	45008798	2	+	28162770	OCIAML2	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	0.25183619922892997	[9]	[65]	2	hSpCas9	negative selection	12266966
45008633	45008656	2	-	28162770	OCIAML2	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.0762646346454755	[31]	[186]	0	hSpCas9	negative selection	12266967
45009090	45009113	2	+	28162770	OCIAML3	viability	GAAGGTGGGCAGCATGGACATGG	SIX2	ENSG00000170577	0.3104146996936057	[116]	[437]	3	hSpCas9	negative selection	12436324
45008598	45008621	2	+	28162770	OCIAML3	viability	CCAGTTGCTGACCTGTGTGGTGG	SIX2	ENSG00000170577	-0.49852733146993483	[94]	[202]	-4	hSpCas9	negative selection	12436325
45008825	45008848	2	-	28162770	OCIAML3	viability	CAAGGCACACTACATCGAGGCGG	SIX2	ENSG00000170577	0.22996199558433733	[73]	[261]	2	hSpCas9	negative selection	12436326
45009037	45009060	2	-	28162770	OCIAML3	viability	TGCGAGGTGCTGCAGCAGGGCGG	SIX2	ENSG00000170577	-0.4348090454749092	[59]	[133]	-3	hSpCas9	negative selection	12436327
45008976	45008999	2	+	28162770	OCIAML3	viability	CTTGTGAAGGTGCTCGCAGGCGG	SIX2	ENSG00000170577	0.8654239783131339	[9]	[54]	7	hSpCas9	negative selection	12436328
45008942	45008965	2	-	28162770	OCIAML3	viability	GCTCAAGGCCAAGGCCGTGGTGG	SIX2	ENSG00000170577	0.4248513869271528	[37]	[153]	4	hSpCas9	negative selection	12436329
45008929	45008952	2	-	28162770	OCIAML3	viability	GCCGTGGTGGCCTTCCACCGCGG	SIX2	ENSG00000170577	1.0738478687453379	[30]	[196]	8	hSpCas9	negative selection	12436330
45008852	45008875	2	+	28162770	OCIAML3	viability	ACAGCTGCTGCAGCTTGGCGTGG	SIX2	ENSG00000170577	-0.24783199919012353	[58]	[149]	-2	hSpCas9	negative selection	12436331
45008775	45008798	2	+	28162770	OCIAML3	viability	GCGCACGCGGTATTTGCCCACGG	SIX2	ENSG00000170577	-1.3595423866871401	[16]	[19]	-7	hSpCas9	negative selection	12436332
45008633	45008656	2	-	28162770	OCIAML3	viability	CGAGAAGCGTGAGCTGGCGGAGG	SIX2	ENSG00000170577	0.42705397520366667	[33]	[137]	4	hSpCas9	negative selection	12436333