Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:23049
• Symbol:SMG1
• Description:SMG1 nonsense mediated mRNA decay associated PI3K related kinase

DataSource: http://genomecrispr.dkfz.de/#!/results/SMG1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
18836066	18836089	16	+	26472758	Jiyoye	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-1.1163865745511394	[22]	[7]	-6	hSpCas9	negative selection	151960
18829462	18829485	16	-	26472758	Jiyoye	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-1.8810695871252003	[126]	[25]	-8	hSpCas9	negative selection	151961
18849976	18849999	16	-	26472758	Jiyoye	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-3.8867383372118924	[254]	[12]	-9	hSpCas9	negative selection	151962
18849325	18849348	16	+	26472758	Jiyoye	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.692360292045041	[29]	[6]	-8	hSpCas9	negative selection	151963
18838136	18838159	16	-	26472758	Jiyoye	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-3.345165438547249	[282]	[20]	-9	hSpCas9	negative selection	151964
18838102	18838125	16	-	26472758	Jiyoye	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	0.10107225378019369	[67]	[54]	0	hSpCas9	negative selection	151965
18837314	18837337	16	-	26472758	Jiyoye	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-1.3297902126603327	[179]	[53]	-7	hSpCas9	negative selection	151966
18835113	18835136	16	+	26472758	Jiyoye	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-1.305943470705965	[399]	[121]	-7	hSpCas9	negative selection	151967
18834367	18834390	16	-	26472758	Jiyoye	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-2.5726467365564964	[70]	[8]	-9	hSpCas9	negative selection	151968
18833015	18833038	16	+	26472758	Jiyoye	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-2.9774884687294514	[93]	[8]	-9	hSpCas9	negative selection	151969
18836066	18836089	16	+	26472758	KBM7	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-2.4254961787844014	[366,214]	[35,14]	-9	hSpCas9	negative selection	343078
18829462	18829485	16	-	26472758	KBM7	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-1.2572644179305104	[240,336]	[46,67]	-7	hSpCas9	negative selection	343079
18849976	18849999	16	-	26472758	KBM7	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-3.124931830550661	[1214,672]	[65,34]	-9	hSpCas9	negative selection	343080
18849325	18849348	16	+	26472758	KBM7	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.5623894278306638	[131,90]	[7,25]	-8	hSpCas9	negative selection	343081
18838136	18838159	16	-	26472758	KBM7	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-1.9579056679258753	[654,466]	[46,84]	-8	hSpCas9	negative selection	343082
18838102	18838125	16	-	26472758	KBM7	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-1.0212503712035532	[553,346]	[103,100]	-7	hSpCas9	negative selection	343083
18837314	18837337	16	-	26472758	KBM7	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-0.13985916848152663	[635,546]	[143,347]	-1	hSpCas9	negative selection	343084
18835113	18835136	16	+	26472758	KBM7	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-1.0820336759704448	[1207,1277]	[245,306]	-7	hSpCas9	negative selection	343085
18834367	18834390	16	-	26472758	KBM7	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-1.6922078993320255	[112,79]	[6,19]	-8	hSpCas9	negative selection	343086
18833015	18833038	16	+	26472758	KBM7	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-1.8054503469268706	[527,403]	[68,55]	-8	hSpCas9	negative selection	343087
18836066	18836089	16	+	26472758	Raji	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-1.7093092512633405	[154]	[10]	-8	hSpCas9	negative selection	534196
18829462	18829485	16	-	26472758	Raji	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-1.7191649519173156	[226]	[15]	-8	hSpCas9	negative selection	534197
18849976	18849999	16	-	26472758	Raji	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-2.7136463235810813	[423]	[14]	-9	hSpCas9	negative selection	534198
18849325	18849348	16	+	26472758	Raji	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	1.586551372072159	[32]	[22]	9	hSpCas9	negative selection	534199
18838136	18838159	16	-	26472758	Raji	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-1.2947149081977465	[295]	[27]	-7	hSpCas9	negative selection	534200
18838102	18838125	16	-	26472758	Raji	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-1.4842426956285677	[216]	[17]	-8	hSpCas9	negative selection	534201
18837314	18837337	16	-	26472758	Raji	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-1.1020698302553504	[295]	[31]	-7	hSpCas9	negative selection	534202
18835113	18835136	16	+	26472758	Raji	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-0.656382118136322	[651]	[95]	-5	hSpCas9	negative selection	534203
18834367	18834390	16	-	26472758	Raji	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-2.0011409214045695	[68]	[3]	-8	hSpCas9	negative selection	534204
18833015	18833038	16	+	26472758	Raji	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-1.365104236089144	[221]	[19]	-7	hSpCas9	negative selection	534205
18836066	18836089	16	+	26472758	K562	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-2.7213655569956403	[249]	[31]	-8	hSpCas9	negative selection	725314
18829462	18829485	16	-	26472758	K562	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-0.5812510917712395	[217]	[122]	-4	hSpCas9	negative selection	725315
18849976	18849999	16	-	26472758	K562	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-3.136403056274484	[624]	[59]	-8	hSpCas9	negative selection	725316
18849325	18849348	16	+	26472758	K562	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.5629361943911575	[76]	[21]	-7	hSpCas9	negative selection	725317
18838136	18838159	16	-	26472758	K562	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-3.372965250747087	[539]	[43]	-8	hSpCas9	negative selection	725318
18838102	18838125	16	-	26472758	K562	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-0.8728189476179263	[409]	[188]	-5	hSpCas9	negative selection	725319
18837314	18837337	16	-	26472758	K562	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-1.4281780473800398	[525]	[164]	-6	hSpCas9	negative selection	725320
18835113	18835136	16	+	26472758	K562	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-1.1683961628830273	[1080]	[405]	-6	hSpCas9	negative selection	725321
18834367	18834390	16	-	26472758	K562	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-1.6390672636071277	[106]	[28]	-7	hSpCas9	negative selection	725322
18833015	18833038	16	+	26472758	K562	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-2.9192062854201275	[456]	[50]	-8	hSpCas9	negative selection	725323
18849325	18849348	16	+	26627737	DLD1	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-5.220991784397297	[450]	[1,8,0]	-9	hSpCas9	negative selection	792860
18850015	18850038	16	+	26627737	DLD1	viability	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-3.426986494874378	[342]	[21,6,1]	-9	hSpCas9	negative selection	792861
18850369	18850392	16	-	26627737	DLD1	viability	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-1.8170788647687597	[52]	[1,11,0]	-8	hSpCas9	negative selection	792862
18852075	18852098	16	-	26627737	DLD1	viability	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	-1.9435676964979842	[370]	[1,60,28]	-8	hSpCas9	negative selection	792863
18853715	18853738	16	-	26627737	DLD1	viability	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.4180345087206838	[188]	[59,33,38]	-4	hSpCas9	negative selection	792864
18854801	18854824	16	+	26627737	DLD1	viability	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-2.560181457559298	[1466]	[20,96,110]	-9	hSpCas9	negative selection	792865
18849325	18849348	16	+	26627737	GBM cells	viability after 5 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-2.274568945969816	[202]	[26,17]	-9	hSpCas9	negative selection	875175
18850015	18850038	16	+	26627737	GBM cells	viability after 5 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-0.4888162783974229	[156]	[58,60]	-6	hSpCas9	negative selection	875176
18850369	18850392	16	-	26627737	GBM cells	viability after 5 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-0.9558882095743786	[84]	[39,6]	-9	hSpCas9	negative selection	875177
18852075	18852098	16	-	26627737	GBM cells	viability after 5 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	0.15855769151870525	[141]	[95,73]	2	hSpCas9	negative selection	875178
18853715	18853738	16	-	26627737	GBM cells	viability after 5 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	0.5452769202709852	[114]	[103,75]	7	hSpCas9	negative selection	875179
18854801	18854824	16	+	26627737	GBM cells	viability after 5 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	0.09262354151804875	[507]	[270,309]	1	hSpCas9	negative selection	875180
18849325	18849348	16	+	26627737	GBM cells	viability after 13 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.975499062293728	[202]	[43,14]	-9	hSpCas9	negative selection	957490
18850015	18850038	16	+	26627737	GBM cells	viability after 13 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-1.7767461656701413	[156]	[20,27]	-9	hSpCas9	negative selection	957491
18850369	18850392	16	-	26627737	GBM cells	viability after 13 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-1.6678443793531956	[84]	[8,18]	-9	hSpCas9	negative selection	957492
18852075	18852098	16	-	26627737	GBM cells	viability after 13 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	0.40467734178894316	[141]	[85,114]	5	hSpCas9	negative selection	957493
18853715	18853738	16	-	26627737	GBM cells	viability after 13 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	0.48089719332687586	[114]	[112,65]	6	hSpCas9	negative selection	957494
18854801	18854824	16	+	26627737	GBM cells	viability after 13 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-0.33121335754606074	[507]	[260,184]	-4	hSpCas9	negative selection	957495
18849325	18849348	16	+	26627737	GBM cells	viability after 21 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-2.5237389647202373	[202]	[14,22]	-9	hSpCas9	negative selection	1039805
18850015	18850038	16	+	26627737	GBM cells	viability after 21 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-1.347341564458941	[156]	[32,33]	-8	hSpCas9	negative selection	1039806
18850369	18850392	16	-	26627737	GBM cells	viability after 21 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-1.2104390981105708	[84]	[20,18]	-7	hSpCas9	negative selection	1039807
18852075	18852098	16	-	26627737	GBM cells	viability after 21 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	0.5371253020839934	[141]	[124,99]	5	hSpCas9	negative selection	1039808
18853715	18853738	16	-	26627737	GBM cells	viability after 21 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.594085137421505	[114]	[43,38]	-5	hSpCas9	negative selection	1039809
18854801	18854824	16	+	26627737	GBM cells	viability after 21 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-1.008665267456038	[507]	[144,129]	-7	hSpCas9	negative selection	1039810
18849325	18849348	16	+	26627737	RPE1	viability after 9 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-4.965169501428353	[1327]	[11,14]	-9	hSpCas9	negative selection	1122120
18850015	18850038	16	+	26627737	RPE1	viability after 9 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-2.02124385643458	[432]	[11,60]	-8	hSpCas9	negative selection	1122121
18850369	18850392	16	-	26627737	RPE1	viability after 9 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-2.9821621214734613	[336]	[1,27]	-9	hSpCas9	negative selection	1122122
18852075	18852098	16	-	26627737	RPE1	viability after 9 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	-1.420630907199306	[497]	[83,24]	-7	hSpCas9	negative selection	1122123
18853715	18853738	16	-	26627737	RPE1	viability after 9 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.21072250684096594	[303]	[107,48]	-1	hSpCas9	negative selection	1122124
18854801	18854824	16	+	26627737	RPE1	viability after 9 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-0.8085770765048698	[1429]	[338,147]	-5	hSpCas9	negative selection	1122125
18849325	18849348	16	+	26627737	RPE1	viability after 12 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-2.3626583303630717	[1327]	[81,55]	-9	hSpCas9	negative selection	1204435
18850015	18850038	16	+	26627737	RPE1	viability after 12 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-3.2002319314435352	[432]	[0,24]	-9	hSpCas9	negative selection	1204436
18850369	18850392	16	-	26627737	RPE1	viability after 12 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-2.3866024029807362	[336]	[10,23]	-9	hSpCas9	negative selection	1204437
18852075	18852098	16	-	26627737	RPE1	viability after 12 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	-0.47378471639782715	[497]	[107,83]	-3	hSpCas9	negative selection	1204438
18853715	18853738	16	-	26627737	RPE1	viability after 12 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.7187170800050218	[303]	[70,26]	-5	hSpCas9	negative selection	1204439
18854801	18854824	16	+	26627737	RPE1	viability after 12 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-1.06728776905138	[1429]	[194,170]	-6	hSpCas9	negative selection	1204440
18849325	18849348	16	+	26627737	RPE1	viability after 15 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-2.1992057571488544	[1327]	[120,43]	-8	hSpCas9	negative selection	1286750
18850015	18850038	16	+	26627737	RPE1	viability after 15 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-6.936474340854831	[432]	[0,0]	-9	hSpCas9	negative selection	1286751
18850369	18850392	16	-	26627737	RPE1	viability after 15 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-1.5956085544165428	[336]	[0,60]	-7	hSpCas9	negative selection	1286752
18852075	18852098	16	-	26627737	RPE1	viability after 15 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	-0.5884291964600193	[497]	[82,103]	-4	hSpCas9	negative selection	1286753
18853715	18853738	16	-	26627737	RPE1	viability after 15 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.8493993430985622	[303]	[62,32]	-5	hSpCas9	negative selection	1286754
18854801	18854824	16	+	26627737	RPE1	viability after 15 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-1.244394812985992	[1429]	[100,237]	-6	hSpCas9	negative selection	1286755
18849325	18849348	16	+	26627737	RPE1	viability after 18 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-4.154921521512966	[1327]	[8,31]	-9	hSpCas9	negative selection	1369065
18850015	18850038	16	+	26627737	RPE1	viability after 18 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-6.267726048445805	[432]	[1,0]	-9	hSpCas9	negative selection	1369066
18850369	18850392	16	-	26627737	RPE1	viability after 18 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-3.158585942360518	[336]	[0,19]	-9	hSpCas9	negative selection	1369067
18852075	18852098	16	-	26627737	RPE1	viability after 18 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	-1.4560425059805988	[497]	[33,64]	-7	hSpCas9	negative selection	1369068
18853715	18853738	16	-	26627737	RPE1	viability after 18 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.9439697904709823	[303]	[75,6]	-5	hSpCas9	negative selection	1369069
18854801	18854824	16	+	26627737	RPE1	viability after 18 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-2.625526630058564	[1429]	[48,76]	-8	hSpCas9	negative selection	1369070
18849325	18849348	16	+	26627737	HeLa	viability after 8 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.100331687800336	[279]	[134,44,10]	-8	hSpCas9	negative selection	1451380
18850015	18850038	16	+	26627737	HeLa	viability after 8 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-5.1707227902058275	[323]	[8,1,1]	-9	hSpCas9	negative selection	1451381
18850369	18850392	16	-	26627737	HeLa	viability after 8 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-2.570084703140857	[227]	[10,37,0]	-9	hSpCas9	negative selection	1451382
18852075	18852098	16	-	26627737	HeLa	viability after 8 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	0.636617360136242	[147]	[173,136,11]	5	hSpCas9	negative selection	1451383
18853715	18853738	16	-	26627737	HeLa	viability after 8 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	1.7925390548213982	[67]	[96,131,78]	9	hSpCas9	negative selection	1451384
18854801	18854824	16	+	26627737	HeLa	viability after 8 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	0.0037154085112045543	[868]	[535,421,224]	0	hSpCas9	negative selection	1451385
18849325	18849348	16	+	26627737	HeLa	viability after 12 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.83245235972006	[279]	[28,35,31]	-9	hSpCas9	negative selection	1533695
18850015	18850038	16	+	26627737	HeLa	viability after 12 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-3.291508789027288	[323]	[0,0,39]	-9	hSpCas9	negative selection	1533696
18850369	18850392	16	-	26627737	HeLa	viability after 12 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-2.0331189193873436	[227]	[4,46,13]	-9	hSpCas9	negative selection	1533697
18852075	18852098	16	-	26627737	HeLa	viability after 12 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	0.3991655407993371	[147]	[89,82,68]	3	hSpCas9	negative selection	1533698
18853715	18853738	16	-	26627737	HeLa	viability after 12 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	1.4955572459973485	[67]	[43,132,53]	8	hSpCas9	negative selection	1533699
18854801	18854824	16	+	26627737	HeLa	viability after 12 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-0.6023609903009979	[868]	[189,361,142]	-5	hSpCas9	negative selection	1533700
18849325	18849348	16	+	26627737	HeLa	viability after 15 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-0.5164438780389141	[279]	[160,69,0]	-4	hSpCas9	negative selection	1616010
18850015	18850038	16	+	26627737	HeLa	viability after 15 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-4.781973222896196	[323]	[11,0,0]	-9	hSpCas9	negative selection	1616011
18850369	18850392	16	-	26627737	HeLa	viability after 15 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-1.9461985685116856	[227]	[19,31,19]	-9	hSpCas9	negative selection	1616012
18852075	18852098	16	-	26627737	HeLa	viability after 15 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	1.62305127151257	[147]	[170,223,159]	9	hSpCas9	negative selection	1616013
18853715	18853738	16	-	26627737	HeLa	viability after 15 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	1.6395728133969731	[67]	[102,99,52]	9	hSpCas9	negative selection	1616014
18854801	18854824	16	+	26627737	HeLa	viability after 15 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-0.47710037508073566	[868]	[282,358,108]	-4	hSpCas9	negative selection	1616015
18849325	18849348	16	+	26627737	HeLa	viability after 18 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-0.48327744258747696	[279]	[109,59,0]	-4	hSpCas9	negative selection	1698325
18850015	18850038	16	+	26627737	HeLa	viability after 18 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-4.369564054833652	[323]	[10,0,0]	-9	hSpCas9	negative selection	1698326
18850369	18850392	16	-	26627737	HeLa	viability after 18 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-1.8982536163870463	[227]	[12,28,19]	-9	hSpCas9	negative selection	1698327
18852075	18852098	16	-	26627737	HeLa	viability after 18 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	1.6329377477781266	[147]	[115,186,159]	9	hSpCas9	negative selection	1698328
18853715	18853738	16	-	26627737	HeLa	viability after 18 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	1.603423174933715	[67]	[63,83,52]	8	hSpCas9	negative selection	1698329
18854801	18854824	16	+	26627737	HeLa	viability after 18 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-0.43934892117611535	[868]	[195,305,108]	-4	hSpCas9	negative selection	1698330
18849325	18849348	16	+	26627737	HCT116	viability after 6 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	0.6494328706823497	[599]	[29,212]	3	hSpCas9	negative selection	1780640
18850015	18850038	16	+	26627737	HCT116	viability after 6 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-2.6985466657229207	[545]	[9,14]	-9	hSpCas9	negative selection	1780641
18850369	18850392	16	-	26627737	HCT116	viability after 6 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-5.031518947140022	[281]	[1,0]	-9	hSpCas9	negative selection	1780642
18852075	18852098	16	-	26627737	HCT116	viability after 6 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	-0.4346148047169929	[233]	[52,12]	-2	hSpCas9	negative selection	1780643
18853715	18853738	16	-	26627737	HCT116	viability after 6 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	1.1777238145154003	[335]	[230,57]	6	hSpCas9	negative selection	1780644
18854801	18854824	16	+	26627737	HCT116	viability after 6 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-0.4599947378276741	[975]	[175,75]	-3	hSpCas9	negative selection	1780645
18849325	18849348	16	+	26627737	HCT116	viability after 8 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.090898662188288	[122]	[15,32,45]	-8	hSpCas9	negative selection	1862955
18850015	18850038	16	+	26627737	HCT116	viability after 8 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-1.1524560479766832	[176]	[23,40,65]	-8	hSpCas9	negative selection	1862956
18850369	18850392	16	-	26627737	HCT116	viability after 8 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-2.305956010186797	[251]	[10,49,22]	-9	hSpCas9	negative selection	1862957
18852075	18852098	16	-	26627737	HCT116	viability after 8 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	0.8603728879225909	[78]	[113,67,55]	7	hSpCas9	negative selection	1862958
18853715	18853738	16	-	26627737	HCT116	viability after 8 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	0.14356123132964793	[163]	[108,120,69]	1	hSpCas9	negative selection	1862959
18854801	18854824	16	+	26627737	HCT116	viability after 8 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-0.15091494958523766	[584]	[268,259,340]	-2	hSpCas9	negative selection	1862960
18849325	18849348	16	+	26627737	HCT116	viability after 9 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.8136082216852476	[599]	[20,64]	-8	hSpCas9	negative selection	1945270
18850015	18850038	16	+	26627737	HCT116	viability after 9 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-0.7258270604023238	[545]	[38,126]	-5	hSpCas9	negative selection	1945271
18850369	18850392	16	-	26627737	HCT116	viability after 9 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-1.5010117662614768	[281]	[58,0]	-8	hSpCas9	negative selection	1945272
18852075	18852098	16	-	26627737	HCT116	viability after 9 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	0.40652925068693757	[233]	[74,88]	3	hSpCas9	negative selection	1945273
18853715	18853738	16	-	26627737	HCT116	viability after 9 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.8649459501693377	[335]	[103,5]	-6	hSpCas9	negative selection	1945274
18854801	18854824	16	+	26627737	HCT116	viability after 9 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	0.7235028516002027	[975]	[784,149]	5	hSpCas9	negative selection	1945275
18849325	18849348	16	+	26627737	HCT116	viability after 12 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.4947805738766062	[122]	[42,20,2]	-9	hSpCas9	negative selection	2027585
18850015	18850038	16	+	26627737	HCT116	viability after 12 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-1.9717143575436065	[176]	[35,20,12]	-9	hSpCas9	negative selection	2027586
18850369	18850392	16	-	26627737	HCT116	viability after 12 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-2.5060640341218976	[251]	[4,41,24]	-9	hSpCas9	negative selection	2027587
18852075	18852098	16	-	26627737	HCT116	viability after 12 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	1.8012935845868299	[78]	[107,213,116]	9	hSpCas9	negative selection	2027588
18853715	18853738	16	-	26627737	HCT116	viability after 12 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.05180330309260728	[163]	[74,117,57]	0	hSpCas9	negative selection	2027589
18854801	18854824	16	+	26627737	HCT116	viability after 12 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-0.6379870274918082	[584]	[102,156,339]	-6	hSpCas9	negative selection	2027590
18849325	18849348	16	+	26627737	HCT116	viability after 15 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.4037122482367947	[122]	[47,33,0]	-8	hSpCas9	negative selection	2109900
18850015	18850038	16	+	26627737	HCT116	viability after 15 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-2.152741172831737	[176]	[56,14,0]	-9	hSpCas9	negative selection	2109901
18850369	18850392	16	-	26627737	HCT116	viability after 15 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-2.4861979157152647	[251]	[5,36,31]	-9	hSpCas9	negative selection	2109902
18852075	18852098	16	-	26627737	HCT116	viability after 15 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	0.8487405160128594	[78]	[105,53,87]	7	hSpCas9	negative selection	2109903
18853715	18853738	16	-	26627737	HCT116	viability after 15 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.3546502885945737	[163]	[67,54,96]	-4	hSpCas9	negative selection	2109904
18854801	18854824	16	+	26627737	HCT116	viability after 15 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-0.8236264833135962	[584]	[124,280,155]	-7	hSpCas9	negative selection	2109905
18849325	18849348	16	+	26627737	HCT116	viability after 18 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-0.8965583685405636	[122]	[61,0,34]	-7	hSpCas9	negative selection	2192215
18850015	18850038	16	+	26627737	HCT116	viability after 18 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-0.979931316569941	[176]	[128,0,0]	-7	hSpCas9	negative selection	2192216
18850369	18850392	16	-	26627737	HCT116	viability after 18 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-3.8271485866165875	[251]	[0,0,24]	-9	hSpCas9	negative selection	2192217
18852075	18852098	16	-	26627737	HCT116	viability after 18 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	1.4522359870360355	[78]	[170,55,88]	8	hSpCas9	negative selection	2192218
18853715	18853738	16	-	26627737	HCT116	viability after 18 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.11944140629923161	[163]	[67,48,104]	-1	hSpCas9	negative selection	2192219
18854801	18854824	16	+	26627737	HCT116	viability after 18 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-0.4712330961516975	[584]	[145,347,103]	-4	hSpCas9	negative selection	2192220
18876258	18876281	16	+	24336569	HL60	viability	GAAGTTGTAGACTGTGTAGGAGG	SMG1	ENSG00000157106	-0.08784677601912838	[1698]	[3382]	0	hSpCas9	negative selection	2295953
18882248	18882271	16	-	24336569	HL60	viability	AAAGCTGGCTGCACTTCTCCGGG	SMG1	ENSG00000157106	-0.7785681062067321	[701]	[865]	-6	hSpCas9	negative selection	2295954
18884084	18884107	16	-	24336569	HL60	viability	TGGTCAGTTTCTGGAAGACATGG	SMG1	ENSG00000157106	-0.1270198263855188	[562]	[1090]	-1	hSpCas9	negative selection	2295955
18884093	18884116	16	-	24336569	HL60	viability	TACTCTTCTTGGTCAGTTTCTGG	SMG1	ENSG00000157106	0.6676177798533668	[165]	[557]	6	hSpCas9	negative selection	2295956
18892268	18892291	16	-	24336569	HL60	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.5962617999614638	[917]	[1284]	-5	hSpCas9	negative selection	2295957
18896866	18896889	16	+	24336569	HL60	viability	TGAAGGTTGCAGTCCATAAGAGG	SMG1	ENSG00000157106	1.0619747034795348	[848]	[3750]	7	hSpCas9	negative selection	2295958
18925956	18925979	16	+	24336569	HL60	viability	TGCCAGTCATTCCAGCTCCGCGG	SMG1	ENSG00000157106	-0.07611747916341816	[807]	[1621]	0	hSpCas9	negative selection	2295959
18925964	18925987	16	+	24336569	HL60	viability	ATTCCAGCTCCGCGGATACTTGG	SMG1	ENSG00000157106	0.05444396258698009	[657]	[1445]	0	hSpCas9	negative selection	2295960
18925973	18925996	16	-	24336569	HL60	viability	GCGGCGGCACCAAGTATCCGCGG	SMG1	ENSG00000157106	-0.08869566985997233	[499]	[994]	0	hSpCas9	negative selection	2295961
18925998	18926021	16	-	24336569	HL60	viability	TCTCGGCTGAGCAGCGGCGGCGG	SMG1	ENSG00000157106	-0.6500321630993838	[349]	[471]	-5	hSpCas9	negative selection	2295962
18876258	18876281	16	+	24336569	KBM7	viability	GAAGTTGTAGACTGTGTAGGAGG	SMG1	ENSG00000157106	-0.6971284037732985	[1362]	[2292]	-5	hSpCas9	negative selection	2363130
18882248	18882271	16	-	24336569	KBM7	viability	AAAGCTGGCTGCACTTCTCCGGG	SMG1	ENSG00000157106	-1.5960046191192143	[357]	[322]	-8	hSpCas9	negative selection	2363131
18884084	18884107	16	-	24336569	KBM7	viability	TGGTCAGTTTCTGGAAGACATGG	SMG1	ENSG00000157106	-2.4516034531076776	[358]	[178]	-8	hSpCas9	negative selection	2363132
18884093	18884116	16	-	24336569	KBM7	viability	TACTCTTCTTGGTCAGTTTCTGG	SMG1	ENSG00000157106	-0.05782573687323883	[294]	[772]	0	hSpCas9	negative selection	2363133
18892268	18892291	16	-	24336569	KBM7	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.12478226993343089	[663]	[1660]	-1	hSpCas9	negative selection	2363134
18896866	18896889	16	+	24336569	KBM7	viability	TGAAGGTTGCAGTCCATAAGAGG	SMG1	ENSG00000157106	-0.5050646912096428	[831]	[1598]	-4	hSpCas9	negative selection	2363135
18925956	18925979	16	+	24336569	KBM7	viability	TGCCAGTCATTCCAGCTCCGCGG	SMG1	ENSG00000157106	0.5889922183736924	[593]	[2436]	5	hSpCas9	negative selection	2363136
18925964	18925987	16	+	24336569	KBM7	viability	ATTCCAGCTCCGCGGATACTTGG	SMG1	ENSG00000157106	-0.07707835646658606	[513]	[1328]	0	hSpCas9	negative selection	2363137
18925973	18925996	16	-	24336569	KBM7	viability	GCGGCGGCACCAAGTATCCGCGG	SMG1	ENSG00000157106	-0.01750229780589746	[500]	[1349]	0	hSpCas9	negative selection	2363138
18925998	18926021	16	-	24336569	KBM7	viability	TCTCGGCTGAGCAGCGGCGGCGG	SMG1	ENSG00000157106	1.3811846185677492	[85]	[610]	9	hSpCas9	negative selection	2363139
18913907	18913930	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCCCAGCACTTCGGGAAG	SMG1	ENSG00000157106	-3.9690945324429574	[10,229]	[0,1]	-9	dCas9-VP64	positive selection	2383094
18920193	18920216	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGACGGGGTTTCACCATGTTAG	SMG1	ENSG00000157106	1.7100356304154607	[4,2]	[3,0]	6	dCas9-VP64	positive selection	2409610
18922660	18922683	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGACGGGGTTTCACCATGTCAG	SMG1	ENSG00000157106	1.7100356304154607	[4,2]	[3,0]	6	dCas9-VP64	positive selection	2409639
18894859	18894882	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGCCACTGCACCCCAGCCTGG	SMG1	ENSG00000157106	0.36632392651586576	[208,84]	[58,21]	1	dCas9-VP64	positive selection	2442351
18850877	18850900	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCTCAGCTACTTAG	SMG1	ENSG00000157106	-0.32009396436001514	[73,465]	[65,28]	-1	dCas9-VP64	positive selection	2454559
18891949	18891972	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCAGGAGGCTGCAG	SMG1	ENSG00000157106	1.0101159834039155	[15,74]	[1,39]	4	dCas9-VP64	positive selection	2458776
18913907	18913930	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCCCAGCACTTCGGGAAG	SMG1	ENSG00000157106	-1.0802329755633977	[58,72]	[5,12]	-9	dCas9-VP64	positive selection	2478349
18920193	18920216	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGACGGGGTTTCACCATGTTAG	SMG1	ENSG00000157106	-0.28524240662887035	[88,68]	[26,14]	-3	dCas9-VP64	positive selection	2504865
18922660	18922683	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGACGGGGTTTCACCATGTCAG	SMG1	ENSG00000157106	-0.28524240662887035	[88,68]	[26,14]	-3	dCas9-VP64	positive selection	2504894
18894859	18894882	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGCCACTGCACCCCAGCCTGG	SMG1	ENSG00000157106	-0.6605575882505516	[226,108]	[36,31]	-6	dCas9-VP64	positive selection	2537606
18850877	18850900	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCTCAGCTACTTAG	SMG1	ENSG00000157106	-0.35714226545986627	[161,80]	[51,10]	-4	dCas9-VP64	positive selection	2549814
18891949	18891972	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCAGGAGGCTGCAG	SMG1	ENSG00000157106	-0.13736370075198145	[6,190]	[3,51]	-1	dCas9-VP64	positive selection	2554031
18872183	18872206	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAACCTTAACCAGGACACGAGG	SMG1	ENSG00000157106	-0.19617027053291372	[3,2]	[0,2]	-3	hSpCas9	positive selection	3022141
18868276	18868299	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATTCGACTCTCCATCATGAGGG	SMG1	ENSG00000157106	-1.3062886266465257	[2,1]	[0,0]	-9	hSpCas9	positive selection	3022142
18853586	18853609	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	0.42793838967194364	[2,2]	[0,4]	8	hSpCas9	positive selection	3022143
18859114	18859137	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTAAAGTAGAAAGTCTCAGAGG	SMG1	ENSG00000157106	-0.07239024841955437	[3,4]	[3,2]	-1	hSpCas9	positive selection	3022144
18872183	18872206	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAACCTTAACCAGGACACGAGG	SMG1	ENSG00000157106	-0.41074233532988313	[3,3]	[2,0]	-6	hSpCas9	positive selection	3089999
18868276	18868299	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATTCGACTCTCCATCATGAGGG	SMG1	ENSG00000157106	-0.4678722482668617	[2,2]	[1,0]	-6	hSpCas9	positive selection	3090000
18853586	18853609	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-0.19961519097836466	[2,2]	[1,0]	-3	hSpCas9	positive selection	3090001
18859114	18859137	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTAAAGTAGAAAGTCTCAGAGG	SMG1	ENSG00000157106	-0.4693675081633438	[3,3]	[2,0]	-6	hSpCas9	positive selection	3090002
18896799	18896822	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGTCATTCTGTATGTCAGCGTGG	SMG1	ENSG00000157106	2.556886493304743	[155,155]	[5,5]	8	hSpCas9	positive selection	3393852
18896189	18896212	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTAGGTGGCTACAGTGTCAATGG	SMG1	ENSG00000157106	0.41183616050145994	[114,114]	[0,0]	2	hSpCas9	positive selection	3393853
18896053	18896076	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGTGATTTCCTCATGTCTTTGG	SMG1	ENSG00000157106	-1.9858477720271157	[605,605]	[0,0]	-9	hSpCas9	positive selection	3393854
18872183	18872206	16	-	26780180	HT29	viability (Avana library 4 designs)	ATAACCTTAACCAGGACACGAGG	SMG1	ENSG00000157106	5.34738098474692	[]	[]	9	hSpCas9	negative selection	3460717
18868276	18868299	16	-	26780180	HT29	viability (Avana library 4 designs)	GATTCGACTCTCCATCATGAGGG	SMG1	ENSG00000157106	5.61389923524291	[]	[]	9	hSpCas9	negative selection	3460718
18853585	18853608	16	+	26780180	HT29	viability (Avana library 4 designs)	GTAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	4.32425039586394	[]	[]	9	hSpCas9	negative selection	3460719
18859113	18859136	16	+	26780180	HT29	viability (Avana library 4 designs)	GTTAAAGTAGAAAGTCTCAGAGG	SMG1	ENSG00000157106	4.08768141368266	[]	[]	9	hSpCas9	negative selection	3460720
18853585	18853608	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-2.04166409233317	[]	[]	-2	hSpCas9	negative selection	3561229
18872183	18872206	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAACCTTAACCAGGACACGAGG	SMG1	ENSG00000157106	-12.4137484687006	[]	[]	-8	hSpCas9	negative selection	3561230
18859113	18859136	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTAAAGTAGAAAGTCTCAGAGG	SMG1	ENSG00000157106	-17.8974198912515	[]	[]	-9	hSpCas9	negative selection	3561231
18868276	18868299	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATTCGACTCTCCATCATGAGGG	SMG1	ENSG00000157106	-17.8682856909003	[]	[]	-9	hSpCas9	negative selection	3561232
18926006	18926029	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCTCAGCCGAGACCCCGGGG	SMG1	ENSG00000157106	-3.59748277399187	[]	[]	-4	hSpCas9	negative selection	3561233
18869211	18869234	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGTCTTCAGGAGATTGCGTGG	SMG1	ENSG00000157106	-12.4805262803123	[]	[]	-8	hSpCas9	negative selection	3561234
18853585	18853608	16	+	26780180	A375	viability (Avana lentiGuide)	GTAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	17.510074931391	[]	[]	8	hSpCas9	negative selection	3669888
18872183	18872206	16	-	26780180	A375	viability (Avana lentiGuide)	ATAACCTTAACCAGGACACGAGG	SMG1	ENSG00000157106	28.186391926289	[]	[]	9	hSpCas9	negative selection	3669889
18859113	18859136	16	+	26780180	A375	viability (Avana lentiGuide)	GTTAAAGTAGAAAGTCTCAGAGG	SMG1	ENSG00000157106	12.2634146783256	[]	[]	7	hSpCas9	negative selection	3669890
18868276	18868299	16	-	26780180	A375	viability (Avana lentiGuide)	GATTCGACTCTCCATCATGAGGG	SMG1	ENSG00000157106	21.3366441614269	[]	[]	9	hSpCas9	negative selection	3669891
18926006	18926029	16	+	26780180	A375	viability (Avana lentiGuide)	GCTGCTCAGCCGAGACCCCGGGG	SMG1	ENSG00000157106	16.3773175443273	[]	[]	8	hSpCas9	negative selection	3669892
18869211	18869234	16	+	26780180	A375	viability (Avana lentiGuide)	TCTGTCTTCAGGAGATTGCGTGG	SMG1	ENSG00000157106	25.6904676685837	[]	[]	9	hSpCas9	negative selection	3669893
18853585	18853608	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-0.6597218811042727	[5]	[3,1]	-7	hSpCas9	positive selection	3778495
18872183	18872206	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAACCTTAACCAGGACACGAGG	SMG1	ENSG00000157106	-0.7344844891472699	[6]	[3,3]	-8	hSpCas9	positive selection	3778496
18859113	18859136	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTAAAGTAGAAAGTCTCAGAGG	SMG1	ENSG00000157106	-1.0071755219061214	[7]	[3,3]	-8	hSpCas9	positive selection	3778497
18868276	18868299	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTCGACTCTCCATCATGAGGG	SMG1	ENSG00000157106	-2.0949499908884333	[5]	[0,0]	-9	hSpCas9	positive selection	3778498
18926006	18926029	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCTCAGCCGAGACCCCGGGG	SMG1	ENSG00000157106	-0.2136433537341712	[3]	[2,3]	-3	hSpCas9	positive selection	3778499
18869211	18869234	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGTCTTCAGGAGATTGCGTGG	SMG1	ENSG00000157106	-2.2904344230626714	[5]	[0,0]	-9	hSpCas9	positive selection	3778500
18853585	18853608	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-0.26045996676321487	[5]	[3,3]	-4	hSpCas9	positive selection	3887102
18872183	18872206	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAACCTTAACCAGGACACGAGG	SMG1	ENSG00000157106	-1.8688148301492302	[6]	[0,1]	-9	hSpCas9	positive selection	3887103
18859113	18859136	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTAAAGTAGAAAGTCTCAGAGG	SMG1	ENSG00000157106	-1.2559825676722105	[7]	[3,0]	-9	hSpCas9	positive selection	3887104
18868276	18868299	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTCGACTCTCCATCATGAGGG	SMG1	ENSG00000157106	-1.3780344752189235	[4]	[1,0]	-9	hSpCas9	positive selection	3887105
18926006	18926029	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCTCAGCCGAGACCCCGGGG	SMG1	ENSG00000157106	-1.37986399360377	[4]	[0,1]	-9	hSpCas9	positive selection	3887106
18869211	18869234	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGTCTTCAGGAGATTGCGTGG	SMG1	ENSG00000157106	-1.4033612356476801	[5]	[0,2]	-9	hSpCas9	positive selection	3887107
18892268	18892291	16	-	26780180	A375	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	1.10774410551858	[]	[]	5	hSpCas9	negative selection	3997221
18892305	18892328	16	-	26780180	A375	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	-0.473522727817762	[]	[]	-9	hSpCas9	negative selection	3997222
18892268	18892291	16	-	26780180	HT29	viability (GeCKOv2 library)	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	1.06904699385112	[]	[]	5	hSpCas9	negative selection	4105187
18892305	18892328	16	-	26780180	HT29	viability (GeCKOv2 library)	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.177867377701334	[]	[]	0	hSpCas9	negative selection	4105188
18892305	18892328	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.5044226692140112	[4]	[5,4]	9	hSpCas9	positive selection	4299327
18892268	18892291	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.2539868064870423	[1]	[0,0]	-5	hSpCas9	positive selection	4299328
18850008	18850030	16	-	27760321	OCIAML3	viability	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	-0.12133929580510992	[477,442]	[262,419]	-1	hSpCas9	negative selection	4441382
18853586	18853608	16	+	27760321	OCIAML3	viability	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-1.2382809879916254	[724,684]	[193,285]	-8	hSpCas9	negative selection	4441383
18853619	18853641	16	-	27760321	OCIAML3	viability	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-1.033556652070226	[280,227]	[84,111]	-7	hSpCas9	negative selection	4441384
18882185	18882207	16	+	27760321	OCIAML3	viability	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	-0.1847779382390865	[276,243]	[141,226]	-2	hSpCas9	negative selection	4441385
18850008	18850030	16	-	27760321	OCIAML2	viability	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	0.3993578377543461	[477,442]	[430,570]	5	hSpCas9	negative selection	4524845
18853586	18853608	16	+	27760321	OCIAML2	viability	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-1.7389048261917879	[724,684]	[145,203]	-9	hSpCas9	negative selection	4524846
18853619	18853641	16	-	27760321	OCIAML2	viability	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-0.7836384918020567	[280,227]	[102,139]	-7	hSpCas9	negative selection	4524847
18882185	18882207	16	+	27760321	OCIAML2	viability	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	-0.20616110347439465	[276,243]	[155,216]	-3	hSpCas9	negative selection	4524848
18850008	18850030	16	-	27760321	MV411	viability	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	-0.16168461654951594	[477,442]	[164,431]	-1	hSpCas9	negative selection	4608308
18853586	18853608	16	+	27760321	MV411	viability	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-0.47241414734229265	[724,684]	[140,627]	-3	hSpCas9	negative selection	4608309
18853619	18853641	16	-	27760321	MV411	viability	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	0.5541160516171898	[280,227]	[353,81]	4	hSpCas9	negative selection	4608310
18882185	18882207	16	+	27760321	MV411	viability	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	-0.5447433320711048	[276,243]	[137,86]	-4	hSpCas9	negative selection	4608311
18850008	18850030	16	-	27760321	HL60	viability	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	-0.43924022158864245	[477,442]	[309,242]	-5	hSpCas9	negative selection	4691771
18853586	18853608	16	+	27760321	HL60	viability	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-0.6718865540098153	[724,684]	[322,402]	-6	hSpCas9	negative selection	4691772
18853619	18853641	16	-	27760321	HL60	viability	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-0.8696791569041389	[280,227]	[118,106]	-7	hSpCas9	negative selection	4691773
18882185	18882207	16	+	27760321	HL60	viability	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	0.7990368342851589	[276,243]	[254,490]	8	hSpCas9	negative selection	4691774
18850008	18850030	16	-	27760321	HT1080	viability	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	1.4730568503661208	[442,345]	[526,336]	7	hSpCas9	negative selection	4775234
18853586	18853608	16	+	27760321	HT1080	viability	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-2.1079843483735305	[684,534]	[0,116]	-6	hSpCas9	negative selection	4775235
18853619	18853641	16	-	27760321	HT1080	viability	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-3.8256144345163	[227,177]	[9,0]	-8	hSpCas9	negative selection	4775236
18882185	18882207	16	+	27760321	HT1080	viability	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	-0.47358810289467623	[243,190]	[49,75]	-2	hSpCas9	negative selection	4775237
18850008	18850030	16	-	27760321	HT29	viability after 7 days	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	-0.3988588644389589	[442,345]	[314,295,527]	-5	hSpCas9	negative selection	4858697
18853586	18853608	16	+	27760321	HT29	viability after 7 days	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-1.2307137846823353	[684,534]	[376,257,371]	-9	hSpCas9	negative selection	4858698
18853619	18853641	16	-	27760321	HT29	viability after 7 days	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-0.21085408410140716	[227,177]	[264,227,189]	-3	hSpCas9	negative selection	4858699
18882185	18882207	16	+	27760321	HT29	viability after 7 days	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	-0.3264661880915236	[243,190]	[428,166,105]	-5	hSpCas9	negative selection	4858700
18850008	18850030	16	-	27760321	HT29	viability after 25 days	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	-0.15512681558295904	[442,345]	[423,382,405]	-1	hSpCas9	negative selection	4942160
18853586	18853608	16	+	27760321	HT29	viability after 25 days	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-2.6694167599395047	[684,534]	[39,96,205]	-8	hSpCas9	negative selection	4942161
18853619	18853641	16	-	27760321	HT29	viability after 25 days	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-2.1665758997157347	[227,177]	[59,54,37]	-8	hSpCas9	negative selection	4942162
18882185	18882207	16	+	27760321	HT29	viability after 25 days	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	0.06220081500833674	[243,190]	[204,176,415]	0	hSpCas9	negative selection	4942163
18850008	18850030	16	-	27760321	HT29	viability after 22 days	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	-0.04396616760762087	[442,345]	[608,339,372]	0	hSpCas9	negative selection	5025623
18853586	18853608	16	+	27760321	HT29	viability after 22 days	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-3.6753274262416715	[684,534]	[10,78,76]	-9	hSpCas9	negative selection	5025624
18853619	18853641	16	-	27760321	HT29	viability after 22 days	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-0.9799093769939556	[227,177]	[170,122,60]	-6	hSpCas9	negative selection	5025625
18882185	18882207	16	+	27760321	HT29	viability after 22 days	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	0.19942358658945447	[243,190]	[549,148,158]	2	hSpCas9	negative selection	5025626
18850008	18850030	16	-	27760321	HT29	viability after 19 days	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	-0.5315733819025442	[442,345]	[514,171,271]	-4	hSpCas9	negative selection	5109086
18853586	18853608	16	+	27760321	HT29	viability after 19 days	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-2.4121215827344753	[684,534]	[80,97,205]	-8	hSpCas9	negative selection	5109087
18853619	18853641	16	-	27760321	HT29	viability after 19 days	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-1.5191848223457236	[227,177]	[70,172,0]	-7	hSpCas9	negative selection	5109088
18882185	18882207	16	+	27760321	HT29	viability after 19 days	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	-1.1014051721169744	[243,190]	[128,126,93]	-7	hSpCas9	negative selection	5109089
18850008	18850030	16	-	27760321	HT29	viability after 16 days	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	-0.5667581106516519	[442,345]	[408,275,219]	-5	hSpCas9	negative selection	5192549
18853586	18853608	16	+	27760321	HT29	viability after 16 days	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-2.4307701620440625	[684,534]	[226,57,105]	-8	hSpCas9	negative selection	5192550
18853619	18853641	16	-	27760321	HT29	viability after 16 days	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-2.0081173939880532	[227,177]	[82,51,36]	-8	hSpCas9	negative selection	5192551
18882185	18882207	16	+	27760321	HT29	viability after 16 days	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	-0.49663003601538946	[243,190]	[289,117,121]	-5	hSpCas9	negative selection	5192552
18850008	18850030	16	-	27760321	HT29	viability after 13 days	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	-0.5183289445189558	[442,345]	[279,449,233]	-5	hSpCas9	negative selection	5276012
18853586	18853608	16	+	27760321	HT29	viability after 13 days	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-2.4646385430695505	[684,534]	[121,157,105]	-9	hSpCas9	negative selection	5276013
18853619	18853641	16	-	27760321	HT29	viability after 13 days	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-0.7944626530515554	[227,177]	[158,141,107]	-7	hSpCas9	negative selection	5276014
18882185	18882207	16	+	27760321	HT29	viability after 13 days	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	-0.3940107034296414	[243,190]	[172,156,242]	-4	hSpCas9	negative selection	5276015
18850008	18850030	16	-	27760321	HT29	viability after 10 days	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	-0.30637234506295324	[442,345]	[396,299,492]	-4	hSpCas9	negative selection	5359475
18853586	18853608	16	+	27760321	HT29	viability after 10 days	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-1.5476207367538637	[684,534]	[360,223,196]	-8	hSpCas9	negative selection	5359476
18853619	18853641	16	-	27760321	HT29	viability after 10 days	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-0.024772789151192298	[227,177]	[177,272,295]	0	hSpCas9	negative selection	5359477
18882185	18882207	16	+	27760321	HT29	viability after 10 days	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	-0.80752771493607	[243,190]	[122,238,106]	-7	hSpCas9	negative selection	5359478
18850008	18850030	16	-	27760321	MOLM13	viability	GGTTGCTCGTGAAGCATGCTGG	SMG1	ENSG00000157106	-3.047501854792445	[477,442]	[65,1]	-9	hSpCas9	negative selection	5442938
18853586	18853608	16	+	27760321	MOLM13	viability	TAGATTCACTCTCGATCCGAGG	SMG1	ENSG00000157106	-0.5962872768064679	[724,684]	[298,232]	-4	hSpCas9	negative selection	5442939
18853619	18853641	16	-	27760321	MOLM13	viability	CTGCCATCTGTTAATACGATGG	SMG1	ENSG00000157106	-0.17864164162996954	[280,227]	[136,116]	-1	hSpCas9	negative selection	5442940
18882185	18882207	16	+	27760321	MOLM13	viability	TAATTGGAGGACCCCGAATTGG	SMG1	ENSG00000157106	0.7385563709475137	[276,243]	[395,115]	5	hSpCas9	negative selection	5442941
18925832	18925855	16	+	27661255	K562	viability	GCCCGGCTCCGAGGGGTGGAGGG	SMG1	ENSG00000157106	0.0573534165890941	[185,249]	[176,182]	2	dCas9-KRAB	negative selection	5512914
18925834	18925857	16	-	27661255	K562	viability	GGCCCTCCACCCCTCGGAGCCGG	SMG1	ENSG00000157106	0.17205620213973022	[998,911]	[964,772]	6	dCas9-KRAB	negative selection	5512915
18925967	18925990	16	-	27661255	K562	viability	GCACCAAGTATCCGCGGAGCTGG	SMG1	ENSG00000157106	-0.15711324974922825	[288,260]	[232,166]	-5	dCas9-KRAB	negative selection	5512916
18925973	18925996	16	-	27661255	K562	viability	GCGGCGGCACCAAGTATCCGCGG	SMG1	ENSG00000157106	-0.034167610430485156	[639,839]	[547,596]	-1	dCas9-KRAB	negative selection	5512917
18926074	18926097	16	-	27661255	K562	viability	GCGACTCGCGCTTCTTTGGGCGG	SMG1	ENSG00000157106	0.11028173954449505	[115,133]	[120,95]	4	dCas9-KRAB	negative selection	5512918
18892305	18892328	16	-	27260156	BXPC3	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.36845626031998235	[1282]	[1546,1599,1839,1989]	7	hSpCas9	negative selection	5571787
18892268	18892291	16	-	27260156	BXPC3	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.4173433984843693	[109]	[134,72,89,34]	-7	hSpCas9	negative selection	5571788
18892305	18892328	16	-	27260156	A673	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.2794030387925388	[1282]	[2098,2059,1577,1755]	6	hSpCas9	negative selection	5693038
18892268	18892291	16	-	27260156	A673	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.19373565891905686	[109]	[161,94,135,71]	-5	hSpCas9	negative selection	5693039
18892305	18892328	16	-	27260156	A375	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.7503125199121259	[1282]	[2352,3614,2611,1738]	9	hSpCas9	negative selection	5814289
18892268	18892291	16	-	27260156	A375	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-2.8493128314368725	[109]	[25,22,4,17]	-9	hSpCas9	negative selection	5814290
18892305	18892328	16	-	27260156	COLO741	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.5424401001378456	[1282]	[2628,2561,2014]	9	hSpCas9	negative selection	5935540
18892268	18892291	16	-	27260156	COLO741	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.6931985941136198	[109]	[104,82,74]	-8	hSpCas9	negative selection	5935541
18892305	18892328	16	-	27260156	CAL120	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.4895480488459545	[1282]	[2517,2209,2040]	7	hSpCas9	negative selection	6056791
18892268	18892291	16	-	27260156	CAL120	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-2.8447669075832316	[109]	[25,1,29]	-9	hSpCas9	negative selection	6056792
18892305	18892328	16	-	27260156	CADOES1	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.5462780561149354	[1282]	[1993,1540,1668,1765]	8	hSpCas9	negative selection	6178042
18892268	18892291	16	-	27260156	CADOES1	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-1.2128293319812213	[109]	[32,41,20,81]	-9	hSpCas9	negative selection	6178043
18892305	18892328	16	-	27260156	EWS502	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.5453156466144986	[1282]	[1746,1923,2199,2095]	8	hSpCas9	negative selection	6299293
18892268	18892291	16	-	27260156	EWS502	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-1.06593188604903	[109]	[80,60,62,10]	-9	hSpCas9	negative selection	6299294
18892305	18892328	16	-	27260156	EW8	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.5513558333062063	[1282]	[1672,1723,1222,1538]	8	hSpCas9	negative selection	6420544
18892268	18892291	16	-	27260156	EW8	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.8245639711100092	[109]	[40,45,68,40]	-9	hSpCas9	negative selection	6420545
18892305	18892328	16	-	27260156	CORL105	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.5074204996670268	[1282]	[1887,2090,2392,2199]	8	hSpCas9	negative selection	6541795
18892268	18892291	16	-	27260156	CORL105	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-1.194325217631612	[109]	[25,44,86,70]	-9	hSpCas9	negative selection	6541796
18892305	18892328	16	-	27260156	HS294T	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.611438258556197	[1282]	[591,565,704,1274]	7	hSpCas9	negative selection	6663046
18892268	18892291	16	-	27260156	HS294T	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.5477000993270997	[109]	[12,38,28,37]	-7	hSpCas9	negative selection	6663047
18892305	18892328	16	-	27260156	HCC44	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.6004339483030718	[1282]	[2571,1623,2302,2409]	8	hSpCas9	negative selection	6784297
18892268	18892291	16	-	27260156	HCC44	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.6231145615389897	[109]	[54,142,86,28]	-7	hSpCas9	negative selection	6784298
18892305	18892328	16	-	27260156	G402	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.8680074514592349	[1282]	[3334,1995,3672,2452]	9	hSpCas9	negative selection	6905548
18892268	18892291	16	-	27260156	G402	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-1.545828603576918	[109]	[95,29,17,45]	-9	hSpCas9	negative selection	6905549
18892305	18892328	16	-	27260156	L33	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.44140106001338175	[1282]	[1693,720,981,1950]	8	hSpCas9	negative selection	7026799
18892268	18892291	16	-	27260156	L33	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.15455830792220437	[109]	[60,45,84,87]	-4	hSpCas9	negative selection	7026800
18892305	18892328	16	-	27260156	K562	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.6669525598805626	[1282]	[2046,1537,2433,1272]	8	hSpCas9	negative selection	7148050
18892268	18892291	16	-	27260156	K562	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-1.8611253351657195	[109]	[14,28,11,47]	-9	hSpCas9	negative selection	7148051
18892305	18892328	16	-	27260156	HT29	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.4263869901686699	[1282]	[2239,2141,2116,1907]	8	hSpCas9	negative selection	7269301
18892268	18892291	16	-	27260156	HT29	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.6034893054411565	[109]	[83,134,82,56]	-7	hSpCas9	negative selection	7269302
18892305	18892328	16	-	27260156	MHHES1	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.3564666690936311	[1282]	[1900,1983,1760,1752]	6	hSpCas9	negative selection	7390552
18892268	18892291	16	-	27260156	MHHES1	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-1.3738683215671443	[109]	[80,65,32,21]	-9	hSpCas9	negative selection	7390553
18892305	18892328	16	-	27260156	MEWO	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.32288293375674426	[1282]	[1829,1199,1538]	7	hSpCas9	negative selection	7511803
18892268	18892291	16	-	27260156	MEWO	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.3161244286105491	[109]	[61,74,106]	-6	hSpCas9	negative selection	7511804
18892305	18892328	16	-	27260156	LNCAPCLONEFGC	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.7096137263590596	[1282]	[1985,1820,2042,1775]	9	hSpCas9	negative selection	7633054
18892268	18892291	16	-	27260156	LNCAPCLONEFGC	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-1.4908666660877596	[109]	[43,21,31,43]	-9	hSpCas9	negative selection	7633055
18892305	18892328	16	-	27260156	PANC0327	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.4341342857225996	[1282]	[1664,1443,1300,1770]	6	hSpCas9	negative selection	7754305
18892268	18892291	16	-	27260156	PANC0327	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-1.0670182636298193	[109]	[111,37,24,17]	-8	hSpCas9	negative selection	7754306
18892305	18892328	16	-	27260156	NCIH2009	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.6444696610885132	[1282]	[3483,2867,2182]	8	hSpCas9	negative selection	7875556
18892268	18892291	16	-	27260156	NCIH2009	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-1.080715222699217	[109]	[78,23,116]	-8	hSpCas9	negative selection	7875557
18892305	18892328	16	-	27260156	NCIH1373	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.8221564119997229	[1282]	[3274,2761,2182,525]	7	hSpCas9	negative selection	7996807
18892268	18892291	16	-	27260156	NCIH1373	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-3.362978513771983	[109]	[1,13,21,1]	-9	hSpCas9	negative selection	7996808
18892305	18892328	16	-	27260156	PATU8902	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.8030405629073627	[1282]	[2743,3445,3165,3077]	8	hSpCas9	negative selection	8118058
18892268	18892291	16	-	27260156	PATU8902	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-2.1460323003090735	[109]	[126,2,2,8]	-9	hSpCas9	negative selection	8118059
18892305	18892328	16	-	27260156	PANC1	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.3530691275281519	[1282]	[1372,1922,1232,1214]	6	hSpCas9	negative selection	8239309
18892268	18892291	16	-	27260156	PANC1	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.669861015122192	[109]	[56,108,50,33]	-7	hSpCas9	negative selection	8239310
18892305	18892328	16	-	27260156	PANC0813	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.7009429538006513	[1282]	[2603,2137,2523,2538]	9	hSpCas9	negative selection	8360560
18892268	18892291	16	-	27260156	PANC0813	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.30854379694075273	[109]	[140,56,72,146]	-5	hSpCas9	negative selection	8360561
18892305	18892328	16	-	27260156	RDES	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.7570027617798694	[1282]	[1909,2485,2649,3075]	9	hSpCas9	negative selection	8481811
18892268	18892291	16	-	27260156	RDES	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-1.0511122930155818	[109]	[30,65,68,86]	-9	hSpCas9	negative selection	8481812
18892305	18892328	16	-	27260156	PC3	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.38750254101611636	[1282]	[1125,1505,2478,1983]	7	hSpCas9	negative selection	8603062
18892268	18892291	16	-	27260156	PC3	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.7593452946025305	[109]	[18,90,106,73]	-9	hSpCas9	negative selection	8603063
18892305	18892328	16	-	27260156	PATU8988T	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.4600247683033598	[1282]	[1459,2254,1612,1531]	7	hSpCas9	negative selection	8724313
18892268	18892291	16	-	27260156	PATU8988T	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.39232436452671227	[109]	[173,63,66,11]	-6	hSpCas9	negative selection	8724314
18892305	18892328	16	-	27260156	T47D	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.37400319084323175	[1282]	[2114,1782,1961,1899]	7	hSpCas9	negative selection	8845564
18892268	18892291	16	-	27260156	T47D	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.7078891375932796	[109]	[82,87,67,73]	-8	hSpCas9	negative selection	8845565
18892305	18892328	16	-	27260156	SU8686	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.7064546864413823	[1282]	[1891,1628,2392,2535]	9	hSpCas9	negative selection	8966815
18892268	18892291	16	-	27260156	SU8686	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-1.412969487922191	[109]	[35,38,51,36]	-9	hSpCas9	negative selection	8966816
18892305	18892328	16	-	27260156	SKES1	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.4229498880055351	[1282]	[1866,1765,1706,1551]	8	hSpCas9	negative selection	9088066
18892268	18892291	16	-	27260156	SKES1	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.37520217906833375	[109]	[87,106,71,74]	-7	hSpCas9	negative selection	9088067
18892305	18892328	16	-	27260156	TOV112D	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.6710368221580958	[1282]	[2347,2175,1596,2114]	9	hSpCas9	negative selection	9209317
18892268	18892291	16	-	27260156	TOV112D	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.5195432891195675	[109]	[105,117,59,36]	-8	hSpCas9	negative selection	9209318
18892305	18892328	16	-	27260156	TC71	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.33754363006669696	[1282]	[1605,1527,1903,1921]	7	hSpCas9	negative selection	9330568
18892268	18892291	16	-	27260156	TC71	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.6927066933802588	[109]	[81,66,36,108]	-9	hSpCas9	negative selection	9330569
18892305	18892328	16	-	27260156	TC32	viability	CTCGACTGTCGAATCTTCTTCGG	SMG1	ENSG00000157106	0.5825019587976739	[1282]	[1873,1316,2363,1831]	8	hSpCas9	negative selection	9451819
18892268	18892291	16	-	27260156	TC32	viability	AGACGACAGAGACCGAAGATTGG	SMG1	ENSG00000157106	-0.9954238029956759	[109]	[41,2,86,101]	-9	hSpCas9	negative selection	9451820
18849325	18849348	16	+	27869803	HPAFII	viability after 27 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-2.420594413159853	[236]	[49,0,NaN]	-8	hSpCas9	negative selection	9555866
18850015	18850038	16	+	27869803	HPAFII	viability after 27 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-4.279085093881626	[187]	[9,0,NaN]	-9	hSpCas9	negative selection	9555867
18850369	18850392	16	-	27869803	HPAFII	viability after 27 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-5.531851164261594	[87]	[0,0,NaN]	-9	hSpCas9	negative selection	9555868
18852075	18852098	16	-	27869803	HPAFII	viability after 27 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	0.05772796452993245	[103]	[81,35,NaN]	0	hSpCas9	negative selection	9555869
18853715	18853738	16	-	27869803	HPAFII	viability after 27 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	0.10517299203070574	[126]	[61,79,NaN]	0	hSpCas9	negative selection	9555870
18854801	18854824	16	+	27869803	HPAFII	viability after 27 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-2.8803374706318317	[465]	[29,35,NaN]	-9	hSpCas9	negative selection	9555871
18849325	18849348	16	+	27869803	HPAFII	viability after 15 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.8057939883628378	[236]	[107,50,NaN]	-9	hSpCas9	negative selection	9638315
18850015	18850038	16	+	27869803	HPAFII	viability after 15 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-2.622146787950367	[187]	[46,23,NaN]	-9	hSpCas9	negative selection	9638316
18850369	18850392	16	-	27869803	HPAFII	viability after 15 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-3.708768758199937	[87]	[5,7,NaN]	-9	hSpCas9	negative selection	9638317
18852075	18852098	16	-	27869803	HPAFII	viability after 15 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	0.8380395941546199	[103]	[258,162,NaN]	8	hSpCas9	negative selection	9638318
18853715	18853738	16	-	27869803	HPAFII	viability after 15 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.06473344204906784	[126]	[148,118,NaN]	0	hSpCas9	negative selection	9638319
18854801	18854824	16	+	27869803	HPAFII	viability after 15 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-0.8282294979019527	[465]	[360,232,NaN]	-7	hSpCas9	negative selection	9638320
18849325	18849348	16	+	27869803	ASPC1	viability after 36 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.8274426370398493	[719]	[159,44,27]	-9	hSpCas9	negative selection	9720764
18850015	18850038	16	+	27869803	ASPC1	viability after 36 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-0.00829271535495435	[7200]	[258,238,5838]	0	hSpCas9	negative selection	9720765
18850369	18850392	16	-	27869803	ASPC1	viability after 36 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	0.2661983639459993	[175]	[220,6,22]	2	hSpCas9	negative selection	9720766
18852075	18852098	16	-	27869803	ASPC1	viability after 36 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	-0.6650741903616411	[359]	[129,10,96]	-6	hSpCas9	negative selection	9720767
18853715	18853738	16	-	27869803	ASPC1	viability after 36 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	0.3976905022629218	[175]	[78,146,28]	4	hSpCas9	negative selection	9720768
18854801	18854824	16	+	27869803	ASPC1	viability after 36 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	0.3745584957243895	[1322]	[476,1279,136]	4	hSpCas9	negative selection	9720769
18849325	18849348	16	+	27869803	PATU8988S	viability after 35 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.2500288560328916	[569]	[104,87,NaN]	-8	hSpCas9	negative selection	9803213
18850015	18850038	16	+	27869803	PATU8988S	viability after 35 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-3.3246898999564354	[421]	[0,32,NaN]	-9	hSpCas9	negative selection	9803214
18850369	18850392	16	-	27869803	PATU8988S	viability after 35 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-1.912562138868204	[219]	[38,7,NaN]	-9	hSpCas9	negative selection	9803215
18852075	18852098	16	-	27869803	PATU8988S	viability after 35 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	-0.7847906328076489	[330]	[23,130,NaN]	-7	hSpCas9	negative selection	9803216
18853715	18853738	16	-	27869803	PATU8988S	viability after 35 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.862917139346318	[254]	[42,69,NaN]	-7	hSpCas9	negative selection	9803217
18854801	18854824	16	+	27869803	PATU8988S	viability after 35 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-1.6348216583637716	[1071]	[150,126,NaN]	-8	hSpCas9	negative selection	9803218
18849325	18849348	16	+	27869803	PATU8988S	viability after 31 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.7944035856787623	[569]	[83,41,NaN]	-9	hSpCas9	negative selection	9885662
18850015	18850038	16	+	27869803	PATU8988S	viability after 31 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-2.643991466193899	[421]	[29,22,NaN]	-9	hSpCas9	negative selection	9885663
18850369	18850392	16	-	27869803	PATU8988S	viability after 31 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-2.3403592914978537	[219]	[26,4,NaN]	-9	hSpCas9	negative selection	9885664
18852075	18852098	16	-	27869803	PATU8988S	viability after 31 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	-0.8002151210466567	[330]	[44,114,NaN]	-7	hSpCas9	negative selection	9885665
18853715	18853738	16	-	27869803	PATU8988S	viability after 31 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.3663019166769532	[254]	[77,79,NaN]	-4	hSpCas9	negative selection	9885666
18854801	18854824	16	+	27869803	PATU8988S	viability after 31 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-2.1172214919265193	[1071]	[116,74,NaN]	-9	hSpCas9	negative selection	9885667
18849325	18849348	16	+	27869803	HPAFII	viability after 35 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-3.745627401329002	[236]	[15,0,NaN]	-9	hSpCas9	negative selection	9968111
18850015	18850038	16	+	27869803	HPAFII	viability after 35 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-5.959304117230862	[187]	[1,0,NaN]	-9	hSpCas9	negative selection	9968112
18850369	18850392	16	-	27869803	HPAFII	viability after 35 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-5.477343065640623	[87]	[0,0,NaN]	-9	hSpCas9	negative selection	9968113
18852075	18852098	16	-	27869803	HPAFII	viability after 35 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	-0.6133847318357026	[103]	[40,26,NaN]	-4	hSpCas9	negative selection	9968114
18853715	18853738	16	-	27869803	HPAFII	viability after 35 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.12550031431288355	[126]	[49,68,NaN]	-1	hSpCas9	negative selection	9968115
18854801	18854824	16	+	27869803	HPAFII	viability after 35 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-4.106035227191746	[465]	[0,27,NaN]	-9	hSpCas9	negative selection	9968116
18849325	18849348	16	+	27869803	HPAFII	viability after 31 days	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-3.2038014597882327	[236]	[12,15,NaN]	-9	hSpCas9	negative selection	10050560
18850015	18850038	16	+	27869803	HPAFII	viability after 31 days	GCTTCACGAGCAACCGCAGCAGG	SMG1	ENSG00000157106	-5.690629332168957	[187]	[2,0,NaN]	-9	hSpCas9	negative selection	10050561
18850369	18850392	16	-	27869803	HPAFII	viability after 31 days	AGTTGATATCAAGCTGCCCATGG	SMG1	ENSG00000157106	-5.626060418962039	[87]	[0,0,NaN]	-9	hSpCas9	negative selection	10050562
18852075	18852098	16	-	27869803	HPAFII	viability after 31 days	ACAGGCTGTGTGTCGGCCGGCGG	SMG1	ENSG00000157106	-0.2707722549912004	[103]	[67,26,NaN]	-2	hSpCas9	negative selection	10050563
18853715	18853738	16	-	27869803	HPAFII	viability after 31 days	GATTTCAGGACAGCTGAAACAGG	SMG1	ENSG00000157106	-0.21565032439309084	[126]	[80,39,NaN]	-1	hSpCas9	negative selection	10050564
18854801	18854824	16	+	27869803	HPAFII	viability after 31 days	TGCCAGCAGTCTTGTTGCAAGGG	SMG1	ENSG00000157106	-3.3447146661104505	[465]	[19,31,NaN]	-9	hSpCas9	negative selection	10050565
18836066	18836089	16	+	28162770	P31FUJ	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-2.6775870470872745	[97]	[17]	-9	hSpCas9	negative selection	10239076
18829462	18829485	16	-	28162770	P31FUJ	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-1.8106752803492152	[202]	[67]	-8	hSpCas9	negative selection	10239077
18849976	18849999	16	-	28162770	P31FUJ	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-3.310246289839727	[286]	[33]	-9	hSpCas9	negative selection	10239078
18849325	18849348	16	+	28162770	P31FUJ	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-2.865070419913891	[61]	[9]	-9	hSpCas9	negative selection	10239079
18838136	18838159	16	-	28162770	P31FUJ	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-4.154414305729663	[196]	[12]	-9	hSpCas9	negative selection	10239080
18838102	18838125	16	-	28162770	P31FUJ	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-1.1588016229706017	[113]	[59]	-7	hSpCas9	negative selection	10239081
18837314	18837337	16	-	28162770	P31FUJ	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-0.8645938372830458	[453]	[292]	-6	hSpCas9	negative selection	10239082
18835113	18835136	16	+	28162770	P31FUJ	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-1.387340472425748	[442]	[198]	-7	hSpCas9	negative selection	10239083
18834367	18834390	16	-	28162770	P31FUJ	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-1.959783710007963	[95]	[28]	-8	hSpCas9	negative selection	10239084
18833015	18833038	16	+	28162770	P31FUJ	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-1.741351589616367	[238]	[83]	-8	hSpCas9	negative selection	10239085
18836066	18836089	16	+	28162770	TF1	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10408442
18829462	18829485	16	-	28162770	TF1	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10408443
18849976	18849999	16	-	28162770	TF1	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10408444
18849325	18849348	16	+	28162770	TF1	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10408445
18838136	18838159	16	-	28162770	TF1	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10408446
18838102	18838125	16	-	28162770	TF1	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10408447
18837314	18837337	16	-	28162770	TF1	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	NaN	[NaN]	[247]	1	hSpCas9	negative selection	10408448
18835113	18835136	16	+	28162770	TF1	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10408449
18834367	18834390	16	-	28162770	TF1	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10408450
18833015	18833038	16	+	28162770	TF1	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10408451
18836066	18836089	16	+	28162770	SKM1	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-2.538208732021414	[22]	[6]	-9	hSpCas9	negative selection	10577808
18829462	18829485	16	-	28162770	SKM1	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-0.5324950808270207	[35]	[43]	-4	hSpCas9	negative selection	10577809
18849976	18849999	16	-	28162770	SKM1	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-2.8842859762763484	[70]	[16]	-9	hSpCas9	negative selection	10577810
18849325	18849348	16	+	28162770	SKM1	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-3.7288922936305235	[14]	[1]	-9	hSpCas9	negative selection	10577811
18838136	18838159	16	-	28162770	SKM1	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-0.9188632372745944	[76]	[71]	-6	hSpCas9	negative selection	10577812
18838102	18838125	16	-	28162770	SKM1	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	0.052467419894135614	[29]	[54]	0	hSpCas9	negative selection	10577813
18837314	18837337	16	-	28162770	SKM1	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-1.5029332572738838	[100]	[62]	-7	hSpCas9	negative selection	10577814
18835113	18835136	16	+	28162770	SKM1	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-0.7584365692445394	[110]	[115]	-5	hSpCas9	negative selection	10577815
18834367	18834390	16	-	28162770	SKM1	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-2.1115083152169905	[21]	[8]	-8	hSpCas9	negative selection	10577816
18833015	18833038	16	+	28162770	SKM1	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-1.7872362798613288	[40]	[20]	-8	hSpCas9	negative selection	10577817
18836066	18836089	16	+	28162770	SKM1	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-2.538208732021414	[22]	[6]	-9	hSpCas9	negative selection	10747174
18829462	18829485	16	-	28162770	SKM1	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-0.5324950808270207	[35]	[43]	-4	hSpCas9	negative selection	10747175
18849976	18849999	16	-	28162770	SKM1	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-2.8842859762763484	[70]	[16]	-9	hSpCas9	negative selection	10747176
18849325	18849348	16	+	28162770	SKM1	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-3.7288922936305235	[14]	[1]	-9	hSpCas9	negative selection	10747177
18838136	18838159	16	-	28162770	SKM1	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-0.9188632372745944	[76]	[71]	-6	hSpCas9	negative selection	10747178
18838102	18838125	16	-	28162770	SKM1	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	0.052467419894135614	[29]	[54]	0	hSpCas9	negative selection	10747179
18837314	18837337	16	-	28162770	SKM1	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-1.5029332572738838	[100]	[62]	-7	hSpCas9	negative selection	10747180
18835113	18835136	16	+	28162770	SKM1	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-0.7584365692445394	[110]	[115]	-5	hSpCas9	negative selection	10747181
18834367	18834390	16	-	28162770	SKM1	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-2.1115083152169905	[21]	[8]	-8	hSpCas9	negative selection	10747182
18833015	18833038	16	+	28162770	SKM1	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-1.7872362798613288	[40]	[20]	-8	hSpCas9	negative selection	10747183
18836066	18836089	16	+	28162770	PL21	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-2.17241455346801	[144]	[13]	-8	hSpCas9	negative selection	10916540
18829462	18829485	16	-	28162770	PL21	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-0.44371657528540465	[174]	[55]	-3	hSpCas9	negative selection	10916541
18849976	18849999	16	-	28162770	PL21	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-2.0006227908755854	[330]	[35]	-8	hSpCas9	negative selection	10916542
18849325	18849348	16	+	28162770	PL21	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-0.5703785393879124	[57]	[16]	-4	hSpCas9	negative selection	10916543
18838136	18838159	16	-	28162770	PL21	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-0.6723103357901687	[237]	[64]	-5	hSpCas9	negative selection	10916544
18838102	18838125	16	-	28162770	PL21	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-1.280292302760529	[172]	[30]	-7	hSpCas9	negative selection	10916545
18837314	18837337	16	-	28162770	PL21	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-0.5191239779434272	[269]	[81]	-4	hSpCas9	negative selection	10916546
18835113	18835136	16	+	28162770	PL21	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-0.14592014287094046	[421]	[165]	-1	hSpCas9	negative selection	10916547
18834367	18834390	16	-	28162770	PL21	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-0.19578906184181877	[49]	[18]	-1	hSpCas9	negative selection	10916548
18833015	18833038	16	+	28162770	PL21	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-0.4337324867127824	[179]	[57]	-3	hSpCas9	negative selection	10916549
18836066	18836089	16	+	28162770	P31FUJ	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-2.6775870470872745	[97]	[17]	-9	hSpCas9	negative selection	11085906
18829462	18829485	16	-	28162770	P31FUJ	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-1.8106752803492152	[202]	[67]	-8	hSpCas9	negative selection	11085907
18849976	18849999	16	-	28162770	P31FUJ	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-3.310246289839727	[286]	[33]	-9	hSpCas9	negative selection	11085908
18849325	18849348	16	+	28162770	P31FUJ	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-2.865070419913891	[61]	[9]	-9	hSpCas9	negative selection	11085909
18838136	18838159	16	-	28162770	P31FUJ	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-4.154414305729663	[196]	[12]	-9	hSpCas9	negative selection	11085910
18838102	18838125	16	-	28162770	P31FUJ	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-1.1588016229706017	[113]	[59]	-7	hSpCas9	negative selection	11085911
18837314	18837337	16	-	28162770	P31FUJ	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-0.8645938372830458	[453]	[292]	-6	hSpCas9	negative selection	11085912
18835113	18835136	16	+	28162770	P31FUJ	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-1.387340472425748	[442]	[198]	-7	hSpCas9	negative selection	11085913
18834367	18834390	16	-	28162770	P31FUJ	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-1.959783710007963	[95]	[28]	-8	hSpCas9	negative selection	11085914
18833015	18833038	16	+	28162770	P31FUJ	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-1.741351589616367	[238]	[83]	-8	hSpCas9	negative selection	11085915
18836066	18836089	16	+	28162770	OCIAML5	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-3.0744589922004453	[55]	[11]	-9	hSpCas9	negative selection	11255272
18829462	18829485	16	-	28162770	OCIAML5	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-0.1314489707852743	[70]	[116]	-1	hSpCas9	negative selection	11255273
18849976	18849999	16	-	28162770	OCIAML5	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-1.7515396949100326	[193]	[103]	-7	hSpCas9	negative selection	11255274
18849325	18849348	16	+	28162770	OCIAML5	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-6.2096185754820805	[40]	[0]	-9	hSpCas9	negative selection	11255275
18838136	18838159	16	-	28162770	OCIAML5	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-3.1438326952411066	[141]	[28]	-9	hSpCas9	negative selection	11255276
18838102	18838125	16	-	28162770	OCIAML5	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-0.7525308973130824	[111]	[119]	-5	hSpCas9	negative selection	11255277
18837314	18837337	16	-	28162770	OCIAML5	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-1.4054589925842833	[225]	[153]	-7	hSpCas9	negative selection	11255278
18835113	18835136	16	+	28162770	OCIAML5	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-1.087170043949999	[265]	[225]	-6	hSpCas9	negative selection	11255279
18834367	18834390	16	-	28162770	OCIAML5	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	0.582336253281778	[36]	[99]	5	hSpCas9	negative selection	11255280
18833015	18833038	16	+	28162770	OCIAML5	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-2.1992319572503822	[172]	[67]	-8	hSpCas9	negative selection	11255281
18836066	18836089	16	+	28162770	EOL1	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-2.726503919608394	[200]	[15]	-9	hSpCas9	negative selection	11424638
18829462	18829485	16	-	28162770	EOL1	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-2.938950228524603	[261]	[17]	-9	hSpCas9	negative selection	11424639
18849976	18849999	16	-	28162770	EOL1	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-1.7916592624288743	[551]	[83]	-8	hSpCas9	negative selection	11424640
18849325	18849348	16	+	28162770	EOL1	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-3.0754522284294654	[95]	[5]	-9	hSpCas9	negative selection	11424641
18838136	18838159	16	-	28162770	EOL1	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-1.9512322914979536	[366]	[49]	-8	hSpCas9	negative selection	11424642
18838102	18838125	16	-	28162770	EOL1	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-0.1962043878900756	[273]	[125]	-1	hSpCas9	negative selection	11424643
18837314	18837337	16	-	28162770	EOL1	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-0.04420129444502574	[410]	[209]	0	hSpCas9	negative selection	11424644
18835113	18835136	16	+	28162770	EOL1	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-1.4867666416655918	[515]	[96]	-7	hSpCas9	negative selection	11424645
18834367	18834390	16	-	28162770	EOL1	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-2.675365070616593	[96]	[7]	-9	hSpCas9	negative selection	11424646
18833015	18833038	16	+	28162770	EOL1	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-1.001451646985689	[208]	[54]	-6	hSpCas9	negative selection	11424647
18836066	18836089	16	+	28162770	MOLM13	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-1.4282748074708815	[133]	[35]	-6	hSpCas9	negative selection	11594004
18829462	18829485	16	-	28162770	MOLM13	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-0.7020356198977336	[224]	[99]	-4	hSpCas9	negative selection	11594005
18849976	18849999	16	-	28162770	MOLM13	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-1.090106071576308	[423]	[143]	-5	hSpCas9	negative selection	11594006
18849325	18849348	16	+	28162770	MOLM13	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-2.8051291128618367	[86]	[8]	-8	hSpCas9	negative selection	11594007
18838136	18838159	16	-	28162770	MOLM13	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-0.5053437088926357	[266]	[135]	-3	hSpCas9	negative selection	11594008
18838102	18838125	16	-	28162770	MOLM13	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-0.512302137375241	[216]	[109]	-3	hSpCas9	negative selection	11594009
18837314	18837337	16	-	28162770	MOLM13	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-0.6024999463468192	[440]	[209]	-3	hSpCas9	negative selection	11594010
18835113	18835136	16	+	28162770	MOLM13	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-2.3805337903527803	[676]	[93]	-8	hSpCas9	negative selection	11594011
18834367	18834390	16	-	28162770	MOLM13	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-4.246356136121545	[104]	[3]	-9	hSpCas9	negative selection	11594012
18833015	18833038	16	+	28162770	MOLM13	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-1.215636953660167	[317]	[98]	-6	hSpCas9	negative selection	11594013
18836066	18836089	16	+	28162770	HEL	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-3.340773045211074	[173]	[10]	-9	hSpCas9	negative selection	11763370
18829462	18829485	16	-	28162770	HEL	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-1.9911332692017454	[179]	[28]	-8	hSpCas9	negative selection	11763371
18849976	18849999	16	-	28162770	HEL	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-3.0261461522658903	[406]	[31]	-8	hSpCas9	negative selection	11763372
18849325	18849348	16	+	28162770	HEL	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-5.661041916176746	[78]	[0]	-9	hSpCas9	negative selection	11763373
18838136	18838159	16	-	28162770	HEL	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-2.5442596828008965	[254]	[27]	-8	hSpCas9	negative selection	11763374
18838102	18838125	16	-	28162770	HEL	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-0.1985634219805847	[171]	[95]	-1	hSpCas9	negative selection	11763375
18837314	18837337	16	-	28162770	HEL	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-0.6155731635910339	[365]	[152]	-4	hSpCas9	negative selection	11763376
18835113	18835136	16	+	28162770	HEL	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-0.45077305392278766	[477]	[223]	-3	hSpCas9	negative selection	11763377
18834367	18834390	16	-	28162770	HEL	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-5.1646160900572475	[55]	[0]	-9	hSpCas9	negative selection	11763378
18833015	18833038	16	+	28162770	HEL	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-1.2072357239950355	[291]	[80]	-6	hSpCas9	negative selection	11763379
18836066	18836089	16	+	28162770	MV411	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-2.764535090883301	[120]	[14]	-9	hSpCas9	negative selection	11932736
18829462	18829485	16	-	28162770	MV411	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-1.3375249499383808	[155]	[51]	-7	hSpCas9	negative selection	11932737
18849976	18849999	16	-	28162770	MV411	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-1.6217758416818704	[273]	[74]	-7	hSpCas9	negative selection	11932738
18849325	18849348	16	+	28162770	MV411	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-2.645647245300713	[51]	[6]	-9	hSpCas9	negative selection	11932739
18838136	18838159	16	-	28162770	MV411	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-1.0632047365580721	[190]	[76]	-6	hSpCas9	negative selection	11932740
18838102	18838125	16	-	28162770	MV411	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-0.22345318322958604	[157]	[113]	-2	hSpCas9	negative selection	11932741
18837314	18837337	16	-	28162770	MV411	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-1.0096158780002897	[336]	[140]	-6	hSpCas9	negative selection	11932742
18835113	18835136	16	+	28162770	MV411	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-1.1624382433802898	[371]	[139]	-6	hSpCas9	negative selection	11932743
18834367	18834390	16	-	28162770	MV411	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-1.8494239884698136	[76]	[17]	-8	hSpCas9	negative selection	11932744
18833015	18833038	16	+	28162770	MV411	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-1.6989814090123805	[184]	[47]	-8	hSpCas9	negative selection	11932745
18836066	18836089	16	+	28162770	MONOMAC1	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-1.151233157446429	[92]	[47]	-7	hSpCas9	negative selection	12102102
18829462	18829485	16	-	28162770	MONOMAC1	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-1.6025515722198909	[150]	[56]	-8	hSpCas9	negative selection	12102103
18849976	18849999	16	-	28162770	MONOMAC1	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-2.395816711174051	[201]	[43]	-9	hSpCas9	negative selection	12102104
18849325	18849348	16	+	28162770	MONOMAC1	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-2.1512331574464287	[30]	[7]	-9	hSpCas9	negative selection	12102105
18838136	18838159	16	-	28162770	MONOMAC1	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-2.0349800889505807	[142]	[39]	-8	hSpCas9	negative selection	12102106
18838102	18838125	16	-	28162770	MONOMAC1	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	0.09430292799438558	[142]	[174]	1	hSpCas9	negative selection	12102107
18837314	18837337	16	-	28162770	MONOMAC1	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-0.873688077472564	[202]	[126]	-6	hSpCas9	negative selection	12102108
18835113	18835136	16	+	28162770	MONOMAC1	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-1.419429268396002	[272]	[116]	-8	hSpCas9	negative selection	12102109
18834367	18834390	16	-	28162770	MONOMAC1	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-1.6233016017616517	[42]	[15]	-8	hSpCas9	negative selection	12102110
18833015	18833038	16	+	28162770	MONOMAC1	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-2.232660756790275	[122]	[29]	-9	hSpCas9	negative selection	12102111
18836066	18836089	16	+	28162770	OCIAML2	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-1.8856673245210047	[15]	[23]	-8	hSpCas9	negative selection	12271468
18829462	18829485	16	-	28162770	OCIAML2	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-1.4920034760347283	[33]	[66]	-7	hSpCas9	negative selection	12271469
18849976	18849999	16	-	28162770	OCIAML2	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-4.2681369613434175	[72]	[20]	-9	hSpCas9	negative selection	12271470
18849325	18849348	16	+	28162770	OCIAML2	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-2.4092292805780176	[22]	[23]	-8	hSpCas9	negative selection	12271471
18838136	18838159	16	-	28162770	OCIAML2	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-2.19855027980536	[52]	[63]	-8	hSpCas9	negative selection	12271472
18838102	18838125	16	-	28162770	OCIAML2	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	0.6813732682028888	[17]	[159]	6	hSpCas9	negative selection	12271473
18837314	18837337	16	-	28162770	OCIAML2	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-1.5300083723210927	[61]	[118]	-7	hSpCas9	negative selection	12271474
18835113	18835136	16	+	28162770	OCIAML2	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-0.6666575425792092	[60]	[212]	-5	hSpCas9	negative selection	12271475
18834367	18834390	16	-	28162770	OCIAML2	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-0.778752120604493	[12]	[41]	-5	hSpCas9	negative selection	12271476
18833015	18833038	16	+	28162770	OCIAML2	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-1.2802986131380119	[38]	[88]	-7	hSpCas9	negative selection	12271477
18836066	18836089	16	+	28162770	OCIAML3	viability	GCAGTTGCTCCAGACAGCCACGG	SMG1	ENSG00000157106	-2.9810307634334103	[33]	[12]	-9	hSpCas9	negative selection	12440834
18829462	18829485	16	-	28162770	OCIAML3	viability	TGATCTCTGTAAGAAAGCGGTGG	SMG1	ENSG00000157106	-0.1741043858735032	[36]	[98]	-1	hSpCas9	negative selection	12440835
18849976	18849999	16	-	28162770	OCIAML3	viability	GCAGTATCTGGAGCACGGCTTGG	SMG1	ENSG00000157106	-1.901189149842339	[72]	[58]	-8	hSpCas9	negative selection	12440836
18849325	18849348	16	+	28162770	OCIAML3	viability	GGCGCACATACACTTCAGGGTGG	SMG1	ENSG00000157106	-1.178970141045319	[11]	[15]	-7	hSpCas9	negative selection	12440837
18838136	18838159	16	-	28162770	OCIAML3	viability	GGACTGGACAGCAGGAGGCGAGG	SMG1	ENSG00000157106	-0.46361100306848824	[73]	[161]	-4	hSpCas9	negative selection	12440838
18838102	18838125	16	-	28162770	OCIAML3	viability	GGTGCTGTCTATGGTGGAGGTGG	SMG1	ENSG00000157106	-0.8467737107041298	[55]	[93]	-6	hSpCas9	negative selection	12440839
18837314	18837337	16	-	28162770	OCIAML3	viability	ACTGCAGGGCAAACTACTGGAGG	SMG1	ENSG00000157106	-0.24216396753251335	[104]	[267]	-2	hSpCas9	negative selection	12440840
18835113	18835136	16	+	28162770	OCIAML3	viability	GATGAACTGACACACTGTTGGGG	SMG1	ENSG00000157106	-1.0952017833527217	[91]	[129]	-7	hSpCas9	negative selection	12440841
18834367	18834390	16	-	28162770	OCIAML3	viability	GTTGATCTGACTTCTCGGGATGG	SMG1	ENSG00000157106	-3.4013625623817676	[20]	[5]	-9	hSpCas9	negative selection	12440842
18833015	18833038	16	+	28162770	OCIAML3	viability	GATTCCACTAGAGTCTGCAGGGG	SMG1	ENSG00000157106	-0.009045139603006902	[36]	[110]	0	hSpCas9	negative selection	12440843