Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:64750
• Symbol:SMURF2
• Description:SMAD specific E3 ubiquitin protein ligase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/SMURF2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
64661864	64661887	17	-	26472758	Jiyoye	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	1.0592520780855663	[6]	[10]	7	hSpCas9	negative selection	152506
64580899	64580922	17	-	26472758	Jiyoye	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	0.17976488540280086	[143]	[122]	1	hSpCas9	negative selection	152507
64571810	64571833	17	+	26472758	Jiyoye	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	-0.36585946736785446	[134]	[78]	-3	hSpCas9	negative selection	152508
64547690	64547713	17	-	26472758	Jiyoye	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	0.4537179674429037	[121]	[125]	3	hSpCas9	negative selection	152509
64547605	64547628	17	+	26472758	Jiyoye	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	0.29836189436694827	[233]	[216]	2	hSpCas9	negative selection	152510
64583518	64583541	17	-	26472758	Jiyoye	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.21297654767758256	[82]	[53]	-1	hSpCas9	negative selection	152511
64578550	64578573	17	-	26472758	Jiyoye	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	1.4071753815058734	[15]	[31]	8	hSpCas9	negative selection	152512
64578491	64578514	17	-	26472758	Jiyoye	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.6295678028423215	[53]	[62]	4	hSpCas9	negative selection	152513
64586134	64586157	17	-	26472758	Jiyoye	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	1.090701716710619	[32]	[52]	7	hSpCas9	negative selection	152514
64583505	64583528	17	+	26472758	Jiyoye	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-2.547020928881002	[61]	[7]	-9	hSpCas9	negative selection	152515
64661864	64661887	17	-	26472758	KBM7	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	-0.6677432423899408	[38,5]	[11,0]	-5	hSpCas9	negative selection	343624
64580899	64580922	17	-	26472758	KBM7	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	-0.21676714864854052	[796,602]	[297,264]	-2	hSpCas9	negative selection	343625
64571810	64571833	17	+	26472758	KBM7	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	1.1271992513415905	[347,337]	[372,335]	9	hSpCas9	negative selection	343626
64547690	64547713	17	-	26472758	KBM7	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	0.2594371683476113	[492,376]	[210,270]	2	hSpCas9	negative selection	343627
64547605	64547628	17	+	26472758	KBM7	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	-0.152528556419942	[980,703]	[377,328]	-1	hSpCas9	negative selection	343628
64583518	64583541	17	-	26472758	KBM7	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	0.10632220402833914	[241,138]	[89,97]	1	hSpCas9	negative selection	343629
64578550	64578573	17	-	26472758	KBM7	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	-0.5056191686802899	[158,303]	[88,70]	-4	hSpCas9	negative selection	343630
64578491	64578514	17	-	26472758	KBM7	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.36366429237164954	[246,154]	[159,82]	4	hSpCas9	negative selection	343631
64586134	64586157	17	-	26472758	KBM7	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	0.5604862626676117	[230,132]	[182,69]	6	hSpCas9	negative selection	343632
64583505	64583528	17	+	26472758	KBM7	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.535742920998856	[71,107]	[111,18]	6	hSpCas9	negative selection	343633
64661864	64661887	17	-	26472758	Raji	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	-0.4775789653475573	[17]	[2]	-4	hSpCas9	negative selection	534742
64580899	64580922	17	-	26472758	Raji	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	0.601492605643642	[283]	[99]	5	hSpCas9	negative selection	534743
64571810	64571833	17	+	26472758	Raji	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	1.3940969376769041	[140]	[85]	9	hSpCas9	negative selection	534744
64547690	64547713	17	-	26472758	Raji	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	-0.2865306723394902	[225]	[42]	-2	hSpCas9	negative selection	534745
64547605	64547628	17	+	26472758	Raji	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	0.04993326318969982	[332]	[79]	0	hSpCas9	negative selection	534746
64583518	64583541	17	-	26472758	Raji	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.20381815292070427	[133]	[26]	-2	hSpCas9	negative selection	534747
64578550	64578573	17	-	26472758	Raji	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	0.22155455529291035	[84]	[22]	2	hSpCas9	negative selection	534748
64578491	64578514	17	-	26472758	Raji	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.857405282365252	[87]	[36]	7	hSpCas9	negative selection	534749
64586134	64586157	17	-	26472758	Raji	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	0.3968901525685843	[107]	[32]	4	hSpCas9	negative selection	534750
64583505	64583528	17	+	26472758	Raji	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.4193275416883395	[57]	[17]	4	hSpCas9	negative selection	534751
64661864	64661887	17	-	26472758	K562	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	-0.6300503902496946	[10]	[5]	-4	hSpCas9	negative selection	725860
64580899	64580922	17	-	26472758	K562	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	-0.02154500920601876	[492]	[409]	0	hSpCas9	negative selection	725861
64571810	64571833	17	+	26472758	K562	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	-0.5686498455855508	[252]	[143]	-4	hSpCas9	negative selection	725862
64547690	64547713	17	-	26472758	K562	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	0.3500289156270457	[394]	[424]	2	hSpCas9	negative selection	725863
64547605	64547628	17	+	26472758	K562	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	0.08478349702093146	[715]	[640]	0	hSpCas9	negative selection	725864
64583518	64583541	17	-	26472758	K562	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.5434280355019433	[201]	[116]	-3	hSpCas9	negative selection	725865
64578550	64578573	17	-	26472758	K562	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	0.2616967190982826	[82]	[83]	2	hSpCas9	negative selection	725866
64578491	64578514	17	-	26472758	K562	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.4048833998596929	[152]	[170]	3	hSpCas9	negative selection	725867
64586134	64586157	17	-	26472758	K562	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	0.6110515949822365	[196]	[253]	5	hSpCas9	negative selection	725868
64583505	64583528	17	+	26472758	K562	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	1.1016785555503648	[68]	[124]	8	hSpCas9	negative selection	725869
64562866	64562889	17	-	26627737	DLD1	viability	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.48449319269131785	[729]	[242,274,421]	5	hSpCas9	negative selection	799368
64571882	64571905	17	-	26627737	DLD1	viability	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	1.3071562059998745	[55]	[27,101,7]	9	hSpCas9	negative selection	799369
64578491	64578514	17	-	26627737	DLD1	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	-2.275056288309681	[24]	[0,2,0]	-9	hSpCas9	negative selection	799370
64580965	64580988	17	-	26627737	DLD1	viability	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.7279583225967313	[312]	[165,128,185]	7	hSpCas9	negative selection	799371
64583505	64583528	17	+	26627737	DLD1	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	1.0685446917823511	[193]	[288,44,54]	8	hSpCas9	negative selection	799372
64586137	64586160	17	-	26627737	DLD1	viability	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	-0.40763760128039317	[705]	[81,79,310]	-4	hSpCas9	negative selection	799373
64562866	64562889	17	-	26627737	GBM cells	viability after 5 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.2007043242019717	[403]	[297,199]	3	hSpCas9	negative selection	881683
64571882	64571905	17	-	26627737	GBM cells	viability after 5 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-0.200621798665229	[119]	[38,72]	-3	hSpCas9	negative selection	881684
64578491	64578514	17	-	26627737	GBM cells	viability after 5 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	1.1690030382534298	[16]	[2,37]	9	hSpCas9	negative selection	881685
64580965	64580988	17	-	26627737	GBM cells	viability after 5 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.5611415019335446	[205]	[176,148]	7	hSpCas9	negative selection	881686
64583505	64583528	17	+	26627737	GBM cells	viability after 5 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.2798892779030796	[162]	[62,80]	-4	hSpCas9	negative selection	881687
64586137	64586160	17	-	26627737	GBM cells	viability after 5 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.7631601330857104	[205]	[200,173]	8	hSpCas9	negative selection	881688
64562866	64562889	17	-	26627737	GBM cells	viability after 13 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.2750605885319707	[403]	[342,201]	3	hSpCas9	negative selection	963998
64571882	64571905	17	-	26627737	GBM cells	viability after 13 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-1.397146304044243	[119]	[16,30]	-9	hSpCas9	negative selection	963999
64578491	64578514	17	-	26627737	GBM cells	viability after 13 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.5096938061989915	[16]	[0,22]	6	hSpCas9	negative selection	964000
64580965	64580988	17	-	26627737	GBM cells	viability after 13 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.7213536840288385	[205]	[191,177]	8	hSpCas9	negative selection	964001
64583505	64583528	17	+	26627737	GBM cells	viability after 13 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.5505699597943674	[162]	[66,54]	-6	hSpCas9	negative selection	964002
64586137	64586160	17	-	26627737	GBM cells	viability after 13 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.35725320785861786	[205]	[151,135]	4	hSpCas9	negative selection	964003
64562866	64562889	17	-	26627737	GBM cells	viability after 21 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.2744087269758476	[403]	[277,253]	3	hSpCas9	negative selection	1046313
64571882	64571905	17	-	26627737	GBM cells	viability after 21 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-0.2070458768740906	[119]	[56,55]	-2	hSpCas9	negative selection	1046314
64578491	64578514	17	-	26627737	GBM cells	viability after 21 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	1.3696956400210571	[16]	[26,20]	9	hSpCas9	negative selection	1046315
64580965	64580988	17	-	26627737	GBM cells	viability after 21 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.18203874938726147	[205]	[115,136]	2	hSpCas9	negative selection	1046316
64583505	64583528	17	+	26627737	GBM cells	viability after 21 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.5554724959298849	[162]	[65,54]	-5	hSpCas9	negative selection	1046317
64586137	64586160	17	-	26627737	GBM cells	viability after 21 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.040755308234329296	[205]	[123,106]	0	hSpCas9	negative selection	1046318
64562866	64562889	17	-	26627737	RPE1	viability after 9 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.7760354307244448	[944]	[503,509]	5	hSpCas9	negative selection	1128628
64571882	64571905	17	-	26627737	RPE1	viability after 9 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	2.4467288572618138	[43]	[30,131]	9	hSpCas9	negative selection	1128629
64578491	64578514	17	-	26627737	RPE1	viability after 9 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	3.3774484522261954	[0]	[4,0]	9	hSpCas9	negative selection	1128630
64580965	64580988	17	-	26627737	RPE1	viability after 9 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-1.496864467315889	[732]	[79,82]	-8	hSpCas9	negative selection	1128631
64583505	64583528	17	+	26627737	RPE1	viability after 9 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.38702825302904953	[890]	[211,214]	-3	hSpCas9	negative selection	1128632
64586137	64586160	17	-	26627737	RPE1	viability after 9 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	2.465218658998884	[97]	[161,178]	9	hSpCas9	negative selection	1128633
64562866	64562889	17	-	26627737	RPE1	viability after 12 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.45049514714491534	[944]	[378,312]	3	hSpCas9	negative selection	1210943
64571882	64571905	17	-	26627737	RPE1	viability after 12 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	1.9467374847431063	[43]	[13,78]	8	hSpCas9	negative selection	1210944
64578491	64578514	17	-	26627737	RPE1	viability after 12 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	5.741242984533699	[0]	[26,0]	9	hSpCas9	negative selection	1210945
64580965	64580988	17	-	26627737	RPE1	viability after 12 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-0.3104908742050784	[732]	[117,201]	-2	hSpCas9	negative selection	1210946
64583505	64583528	17	+	26627737	RPE1	viability after 12 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.6661310125479348	[890]	[162,137]	-4	hSpCas9	negative selection	1210947
64586137	64586160	17	-	26627737	RPE1	viability after 12 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	2.2494923196031857	[97]	[131,117]	9	hSpCas9	negative selection	1210948
64562866	64562889	17	-	26627737	RPE1	viability after 15 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.5990017998094606	[944]	[522,290]	4	hSpCas9	negative selection	1293258
64571882	64571905	17	-	26627737	RPE1	viability after 15 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	2.025883408790524	[43]	[11,87]	8	hSpCas9	negative selection	1293259
64578491	64578514	17	-	26627737	RPE1	viability after 15 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	3.610330661277315	[0]	[5,0]	9	hSpCas9	negative selection	1293260
64580965	64580988	17	-	26627737	RPE1	viability after 15 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-0.463125209897714	[732]	[98,199]	-3	hSpCas9	negative selection	1293261
64583505	64583528	17	+	26627737	RPE1	viability after 15 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.2849133015307132	[890]	[241,172]	-2	hSpCas9	negative selection	1293262
64586137	64586160	17	-	26627737	RPE1	viability after 15 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	1.294597868281632	[97]	[123,13]	7	hSpCas9	negative selection	1293263
64562866	64562889	17	-	26627737	RPE1	viability after 18 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.5053814033668989	[944]	[201,532]	3	hSpCas9	negative selection	1375573
64571882	64571905	17	-	26627737	RPE1	viability after 18 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	2.154152298624683	[43]	[33,72]	9	hSpCas9	negative selection	1375574
64578491	64578514	17	-	26627737	RPE1	viability after 18 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	5.633625239224733	[0]	[24,0]	9	hSpCas9	negative selection	1375575
64580965	64580988	17	-	26627737	RPE1	viability after 18 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-0.11021048111492959	[732]	[190,174]	0	hSpCas9	negative selection	1375576
64583505	64583528	17	+	26627737	RPE1	viability after 18 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-1.2499133084735596	[890]	[74,128]	-6	hSpCas9	negative selection	1375577
64586137	64586160	17	-	26627737	RPE1	viability after 18 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	2.2200832300815283	[97]	[85,162]	9	hSpCas9	negative selection	1375578
64562866	64562889	17	-	26627737	HeLa	viability after 8 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	-0.13382674191023514	[699]	[421,318,133]	-1	hSpCas9	negative selection	1457888
64571882	64571905	17	-	26627737	HeLa	viability after 8 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	0.5946340047112317	[75]	[125,11,29]	5	hSpCas9	negative selection	1457889
64578491	64578514	17	-	26627737	HeLa	viability after 8 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	5.366611696690567	[0]	[7,0,40]	9	hSpCas9	negative selection	1457890
64580965	64580988	17	-	26627737	HeLa	viability after 8 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.9938542609847032	[68]	[54,117,8]	7	hSpCas9	negative selection	1457891
64583505	64583528	17	+	26627737	HeLa	viability after 8 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-1.532799720017544	[348]	[93,40,32]	-9	hSpCas9	negative selection	1457892
64586137	64586160	17	-	26627737	HeLa	viability after 8 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	-0.3777574777199587	[579]	[281,154,166]	-4	hSpCas9	negative selection	1457893
64562866	64562889	17	-	26627737	HeLa	viability after 12 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	-0.627888161540362	[699]	[169,225,160]	-5	hSpCas9	negative selection	1540203
64571882	64571905	17	-	26627737	HeLa	viability after 12 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	1.283691409780395	[75]	[119,44,68]	8	hSpCas9	negative selection	1540204
64578491	64578514	17	-	26627737	HeLa	viability after 12 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	6.035000929317066	[0]	[24,0,57]	9	hSpCas9	negative selection	1540205
64580965	64580988	17	-	26627737	HeLa	viability after 12 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.9482519440309023	[68]	[44,33,87]	7	hSpCas9	negative selection	1540206
64583505	64583528	17	+	26627737	HeLa	viability after 12 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.5700711059898206	[348]	[83,144,56]	-5	hSpCas9	negative selection	1540207
64586137	64586160	17	-	26627737	HeLa	viability after 12 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	-0.1465484698144272	[579]	[213,183,254]	-1	hSpCas9	negative selection	1540208
64562866	64562889	17	-	26627737	HeLa	viability after 15 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	-0.09368391042301427	[699]	[460,138,192]	-1	hSpCas9	negative selection	1622518
64571882	64571905	17	-	26627737	HeLa	viability after 15 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	2.042623012117483	[75]	[223,79,72]	9	hSpCas9	negative selection	1622519
64578491	64578514	17	-	26627737	HeLa	viability after 15 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	1.691055233009461	[0]	[0,0,1]	9	hSpCas9	negative selection	1622520
64580965	64580988	17	-	26627737	HeLa	viability after 15 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	1.8325685410282	[68]	[13,141,148]	9	hSpCas9	negative selection	1622521
64583505	64583528	17	+	26627737	HeLa	viability after 15 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.9800542072028946	[348]	[36,113,64]	-7	hSpCas9	negative selection	1622522
64586137	64586160	17	-	26627737	HeLa	viability after 15 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	-0.001560361827546708	[579]	[196,215,299]	0	hSpCas9	negative selection	1622523
64562866	64562889	17	-	26627737	HeLa	viability after 18 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	-0.13593516203076783	[699]	[291,117,192]	-1	hSpCas9	negative selection	1704833
64571882	64571905	17	-	26627737	HeLa	viability after 18 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	2.0315815285442382	[75]	[150,62,72]	9	hSpCas9	negative selection	1704834
64578491	64578514	17	-	26627737	HeLa	viability after 18 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	1.932883213650304	[0]	[0,0,1]	9	hSpCas9	negative selection	1704835
64580965	64580988	17	-	26627737	HeLa	viability after 18 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	1.8454305419282182	[68]	[9,118,148]	9	hSpCas9	negative selection	1704836
64583505	64583528	17	+	26627737	HeLa	viability after 18 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.9468875367359171	[348]	[25,96,64]	-7	hSpCas9	negative selection	1704837
64586137	64586160	17	-	26627737	HeLa	viability after 18 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.030582652854679426	[579]	[131,191,299]	0	hSpCas9	negative selection	1704838
64562866	64562889	17	-	26627737	HCT116	viability after 6 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	1.9533451465113516	[904]	[1074,261]	8	hSpCas9	negative selection	1787148
64571882	64571905	17	-	26627737	HCT116	viability after 6 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-1.0657351576326954	[162]	[28,2]	-6	hSpCas9	negative selection	1787149
64578491	64578514	17	-	26627737	HCT116	viability after 6 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	-0.5559839046324466	[15]	[2,0]	-3	hSpCas9	negative selection	1787150
64580965	64580988	17	-	26627737	HCT116	viability after 6 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.20991377629128452	[521]	[72,106]	1	hSpCas9	negative selection	1787151
64583505	64583528	17	+	26627737	HCT116	viability after 6 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.23311752956343468	[248]	[123,2]	1	hSpCas9	negative selection	1787152
64586137	64586160	17	-	26627737	HCT116	viability after 6 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	-2.466275433063926	[399]	[2,15]	-8	hSpCas9	negative selection	1787153
64562866	64562889	17	-	26627737	HCT116	viability after 8 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	-0.5109803601019806	[530]	[178,188,246]	-6	hSpCas9	negative selection	1869463
64571882	64571905	17	-	26627737	HCT116	viability after 8 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-0.5554616016722431	[85]	[3,40,50]	-6	hSpCas9	negative selection	1869464
64578491	64578514	17	-	26627737	HCT116	viability after 8 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	3.1769981378582264	[0]	[4,8,0]	9	hSpCas9	negative selection	1869465
64580965	64580988	17	-	26627737	HCT116	viability after 8 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-2.4165105776902633	[386]	[30,75,12]	-9	hSpCas9	negative selection	1869466
64583505	64583528	17	+	26627737	HCT116	viability after 8 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.5383613070230329	[193]	[90,45,83]	-6	hSpCas9	negative selection	1869467
64586137	64586160	17	-	26627737	HCT116	viability after 8 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.9623185994379027	[137]	[139,127,175]	8	hSpCas9	negative selection	1869468
64562866	64562889	17	-	26627737	HCT116	viability after 9 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	1.5342412542285664	[904]	[695,702]	8	hSpCas9	negative selection	1951778
64571882	64571905	17	-	26627737	HCT116	viability after 9 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-0.8544499167536626	[162]	[51,1]	-6	hSpCas9	negative selection	1951779
64578491	64578514	17	-	26627737	HCT116	viability after 9 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	-2.0950101886465315	[15]	[0,0]	-8	hSpCas9	negative selection	1951780
64580965	64580988	17	-	26627737	HCT116	viability after 9 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.37138986121612655	[521]	[267,110]	2	hSpCas9	negative selection	1951781
64583505	64583528	17	+	26627737	HCT116	viability after 9 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.04140626232472733	[248]	[92,48]	0	hSpCas9	negative selection	1951782
64586137	64586160	17	-	26627737	HCT116	viability after 9 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.4305169691604084	[399]	[153,135]	3	hSpCas9	negative selection	1951783
64562866	64562889	17	-	26627737	HCT116	viability after 12 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	-0.5880256920694513	[530]	[126,264,171]	-6	hSpCas9	negative selection	2034093
64571882	64571905	17	-	26627737	HCT116	viability after 12 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-0.6296370695623128	[85]	[44,18,21]	-6	hSpCas9	negative selection	2034094
64578491	64578514	17	-	26627737	HCT116	viability after 12 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	2.7551736922127272	[0]	[0,8,0]	9	hSpCas9	negative selection	2034095
64580965	64580988	17	-	26627737	HCT116	viability after 12 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-0.6172243770580532	[386]	[139,127,128]	-6	hSpCas9	negative selection	2034096
64583505	64583528	17	+	26627737	HCT116	viability after 12 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.7930728513594316	[193]	[46,35,93]	-7	hSpCas9	negative selection	2034097
64586137	64586160	17	-	26627737	HCT116	viability after 12 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.5798789833233208	[137]	[54,153,121]	5	hSpCas9	negative selection	2034098
64562866	64562889	17	-	26627737	HCT116	viability after 15 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	-0.2054512963711772	[530]	[275,185,331]	-2	hSpCas9	negative selection	2116408
64571882	64571905	17	-	26627737	HCT116	viability after 15 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-0.7646585559439931	[85]	[11,32,39]	-7	hSpCas9	negative selection	2116409
64578491	64578514	17	-	26627737	HCT116	viability after 15 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	2.297446599797822	[0]	[6,0,0]	9	hSpCas9	negative selection	2116410
64580965	64580988	17	-	26627737	HCT116	viability after 15 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-0.8945008102474039	[386]	[22,44,276]	-7	hSpCas9	negative selection	2116411
64583505	64583528	17	+	26627737	HCT116	viability after 15 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.8916299621868542	[193]	[77,15,87]	-7	hSpCas9	negative selection	2116412
64586137	64586160	17	-	26627737	HCT116	viability after 15 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.9933070416656402	[137]	[199,165,112]	8	hSpCas9	negative selection	2116413
64562866	64562889	17	-	26627737	HCT116	viability after 18 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	-0.21524814095320677	[530]	[110,166,396]	-2	hSpCas9	negative selection	2198723
64571882	64571905	17	-	26627737	HCT116	viability after 18 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-1.0908656984340335	[85]	[29,19,7]	-7	hSpCas9	negative selection	2198724
64578491	64578514	17	-	26627737	HCT116	viability after 18 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	1.0485523756554223	[0]	[0,0,0]	7	hSpCas9	negative selection	2198725
64580965	64580988	17	-	26627737	HCT116	viability after 18 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-1.1097266341341772	[386]	[110,8,147]	-7	hSpCas9	negative selection	2198726
64583505	64583528	17	+	26627737	HCT116	viability after 18 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-1.7803054480128628	[193]	[3,18,60]	-8	hSpCas9	negative selection	2198727
64586137	64586160	17	-	26627737	HCT116	viability after 18 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.2140606505073377	[137]	[41,118,67]	2	hSpCas9	negative selection	2198728
64658212	64658235	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGCCCACCACCACGCCTGG	SMURF2	ENSG00000108854	1.906510521561382	[74,11]	[56,10]	6	dCas9-VP64	positive selection	2400695
64549685	64549708	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGCAGAGGTTGCGGTAAGTGG	SMURF2	ENSG00000108854	1.5427360698704213	[93,31]	[71,4]	6	dCas9-VP64	positive selection	2413102
64644374	64644397	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGTTTGAGACCAGCCTTGG	SMURF2	ENSG00000108854	-1.6026008362934678	[306,558]	[26,34]	-8	dCas9-VP64	positive selection	2428550
64584290	64584313	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTTTCGCTCTTGTCACCCTGG	SMURF2	ENSG00000108854	0.7275722083534555	[14,18]	[4,6]	3	dCas9-VP64	positive selection	2454190
64658125	64658148	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGCGGATCACCTGAGGTCCAG	SMURF2	ENSG00000108854	8.572613315975907	[14,15]	[366,2389]	9	dCas9-VP64	positive selection	2455539
64650628	64650651	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGTGACCAGCCTGACCAACATGG	SMURF2	ENSG00000108854	-1.5081130691523483	[299,84]	[22,3]	-8	dCas9-VP64	positive selection	2464703
64658212	64658235	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGCCCACCACCACGCCTGG	SMURF2	ENSG00000108854	1.1664475786686166	[321,97]	[88,216]	7	dCas9-VP64	positive selection	2495950
64549685	64549708	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGCAGAGGTTGCGGTAAGTGG	SMURF2	ENSG00000108854	-1.5744090954762409	[353,105]	[38,11]	-9	dCas9-VP64	positive selection	2508357
64644374	64644397	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGTTTGAGACCAGCCTTGG	SMURF2	ENSG00000108854	0.9241793657004961	[25,55]	[22,26]	6	dCas9-VP64	positive selection	2523805
64584290	64584313	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTTTCGCTCTTGTCACCCTGG	SMURF2	ENSG00000108854	0.3552301064276102	[39,27]	[14,12]	3	dCas9-VP64	positive selection	2549445
64658125	64658148	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGCGGATCACCTGAGGTCCAG	SMURF2	ENSG00000108854	1.5525228181942226	[88,74]	[56,98]	8	dCas9-VP64	positive selection	2550794
64650628	64650651	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGTGACCAGCCTGACCAACATGG	SMURF2	ENSG00000108854	-0.5989378574143126	[229,363]	[80,46]	-6	dCas9-VP64	positive selection	2559958
64562923	64562946	17	+	27260157	DLD1	viability	ATACCACTTGCTGTTGCTGTTGG	SMURF2	ENSG00000108854	0.13553515358975	[]	[]	3	hSpCas9	negative selection	2576209
64571882	64571905	17	-	27260157	DLD1	viability	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-1.20777913739499	[]	[]	-7	hSpCas9	negative selection	2576705
64593450	64593473	17	+	27260157	DLD1	viability	TTTGAGGCGGTTGATGGCATTGG	SMURF2	ENSG00000108854	-0.990289795056606	[]	[]	-7	hSpCas9	negative selection	2582245
64571877	64571900	17	+	27260157	DLD1	viability	CTCTGCCTGTTGCCGTATTACGG	SMURF2	ENSG00000108854	0.222920760006599	[]	[]	3	hSpCas9	negative selection	2584704
64580961	64580984	17	+	27260157	DLD1	viability	TCTGCCAGGGCTAGAATATTCGG	SMURF2	ENSG00000108854	0.214303495129475	[]	[]	3	hSpCas9	negative selection	2586676
64578550	64578573	17	-	27260157	DLD1	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	1.06605757384365	[]	[]	9	hSpCas9	negative selection	2608939
64571891	64571914	17	+	27260157	DLD1	viability	GTATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	0.121274417582593	[]	[]	3	hSpCas9	negative selection	2609223
64586134	64586157	17	-	27260157	DLD1	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	0.678885486418533	[]	[]	8	hSpCas9	negative selection	2612674
64562926	64562949	17	-	27260157	DLD1	viability	AGACCAACAGCAACAGCAAGTGG	SMURF2	ENSG00000108854	0.347852258886933	[]	[]	4	hSpCas9	negative selection	2614803
64580965	64580988	17	-	27260157	DLD1	viability	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.488192269851102	[]	[]	8	hSpCas9	negative selection	2616167
64571810	64571833	17	+	27260157	DLD1	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.800683243481325	[]	[]	9	hSpCas9	negative selection	2618033
64583518	64583541	17	-	27260157	DLD1	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	1.61415579448279	[]	[]	9	hSpCas9	negative selection	2618347
64580788	64580811	17	+	27260157	DLD1	viability	CCATAGCCTTCTGGTAGGTCTGG	SMURF2	ENSG00000108854	-1.13959607271474	[]	[]	-7	hSpCas9	negative selection	2619588
64583505	64583528	17	+	27260157	DLD1	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.2033693929659	[]	[]	-1	hSpCas9	negative selection	2623307
64580947	64580970	17	+	27260157	DLD1	viability	AAGCAGCTAAGAGGTCTGCCAGG	SMURF2	ENSG00000108854	0.855006225968712	[]	[]	9	hSpCas9	negative selection	2641359
64580794	64580817	17	-	27260157	DLD1	viability	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	0.561991864039814	[]	[]	8	hSpCas9	negative selection	2646342
64580899	64580922	17	-	27260157	DLD1	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	-0.255875935278765	[]	[]	-2	hSpCas9	negative selection	2647410
64562923	64562946	17	+	27260157	HT1080	viability	ATACCACTTGCTGTTGCTGTTGG	SMURF2	ENSG00000108854	0.957977630108785	[]	[]	7	hSpCas9	negative selection	2652339
64571882	64571905	17	-	27260157	HT1080	viability	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	0.351106884301672	[]	[]	3	hSpCas9	negative selection	2652835
64593450	64593473	17	+	27260157	HT1080	viability	TTTGAGGCGGTTGATGGCATTGG	SMURF2	ENSG00000108854	-0.0788547275680441	[]	[]	0	hSpCas9	negative selection	2658375
64571877	64571900	17	+	27260157	HT1080	viability	CTCTGCCTGTTGCCGTATTACGG	SMURF2	ENSG00000108854	0.874684000169895	[]	[]	7	hSpCas9	negative selection	2660834
64580961	64580984	17	+	27260157	HT1080	viability	TCTGCCAGGGCTAGAATATTCGG	SMURF2	ENSG00000108854	0.149382006727614	[]	[]	1	hSpCas9	negative selection	2662806
64578550	64578573	17	-	27260157	HT1080	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	1.87415466176089	[]	[]	9	hSpCas9	negative selection	2685069
64571891	64571914	17	+	27260157	HT1080	viability	GTATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	0.211192730997529	[]	[]	2	hSpCas9	negative selection	2685353
64586134	64586157	17	-	27260157	HT1080	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	0.199280744438972	[]	[]	2	hSpCas9	negative selection	2688804
64562926	64562949	17	-	27260157	HT1080	viability	AGACCAACAGCAACAGCAAGTGG	SMURF2	ENSG00000108854	0.709297196880516	[]	[]	6	hSpCas9	negative selection	2690933
64580965	64580988	17	-	27260157	HT1080	viability	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.896555658036727	[]	[]	7	hSpCas9	negative selection	2692297
64571810	64571833	17	+	27260157	HT1080	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.582840459624382	[]	[]	5	hSpCas9	negative selection	2694163
64583518	64583541	17	-	27260157	HT1080	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	1.14900335072402	[]	[]	8	hSpCas9	negative selection	2694477
64580788	64580811	17	+	27260157	HT1080	viability	CCATAGCCTTCTGGTAGGTCTGG	SMURF2	ENSG00000108854	0.104996416933115	[]	[]	1	hSpCas9	negative selection	2695718
64583505	64583528	17	+	27260157	HT1080	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.399150392301508	[]	[]	3	hSpCas9	negative selection	2699437
64580947	64580970	17	+	27260157	HT1080	viability	AAGCAGCTAAGAGGTCTGCCAGG	SMURF2	ENSG00000108854	1.72174673118776	[]	[]	9	hSpCas9	negative selection	2717489
64580794	64580817	17	-	27260157	HT1080	viability	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	1.54892015168572	[]	[]	9	hSpCas9	negative selection	2722472
64580899	64580922	17	-	27260157	HT1080	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	0.118147686194507	[]	[]	1	hSpCas9	negative selection	2723540
64562923	64562946	17	+	27260157	MKN45	viability	ATACCACTTGCTGTTGCTGTTGG	SMURF2	ENSG00000108854	-0.0378710451406794	[]	[]	0	hSpCas9	negative selection	2728469
64571882	64571905	17	-	27260157	MKN45	viability	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-0.150657315139412	[]	[]	0	hSpCas9	negative selection	2728965
64593450	64593473	17	+	27260157	MKN45	viability	TTTGAGGCGGTTGATGGCATTGG	SMURF2	ENSG00000108854	-0.645483986994041	[]	[]	-7	hSpCas9	negative selection	2734505
64571877	64571900	17	+	27260157	MKN45	viability	CTCTGCCTGTTGCCGTATTACGG	SMURF2	ENSG00000108854	0.378132737668377	[]	[]	6	hSpCas9	negative selection	2736964
64580961	64580984	17	+	27260157	MKN45	viability	TCTGCCAGGGCTAGAATATTCGG	SMURF2	ENSG00000108854	0.468347929595588	[]	[]	6	hSpCas9	negative selection	2738936
64578550	64578573	17	-	27260157	MKN45	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	1.90382494974056	[]	[]	9	hSpCas9	negative selection	2761199
64571891	64571914	17	+	27260157	MKN45	viability	GTATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	-1.04966129834058	[]	[]	-8	hSpCas9	negative selection	2761483
64586134	64586157	17	-	27260157	MKN45	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	-0.0316725684414012	[]	[]	0	hSpCas9	negative selection	2764934
64562926	64562949	17	-	27260157	MKN45	viability	AGACCAACAGCAACAGCAAGTGG	SMURF2	ENSG00000108854	0.3151827112015	[]	[]	5	hSpCas9	negative selection	2767063
64580965	64580988	17	-	27260157	MKN45	viability	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.841903341696205	[]	[]	8	hSpCas9	negative selection	2768427
64571810	64571833	17	+	27260157	MKN45	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.232104357502477	[]	[]	5	hSpCas9	negative selection	2770293
64583518	64583541	17	-	27260157	MKN45	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.137299358323635	[]	[]	0	hSpCas9	negative selection	2770607
64580788	64580811	17	+	27260157	MKN45	viability	CCATAGCCTTCTGGTAGGTCTGG	SMURF2	ENSG00000108854	0.427131568835194	[]	[]	6	hSpCas9	negative selection	2771848
64583505	64583528	17	+	27260157	MKN45	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.932303175888717	[]	[]	-7	hSpCas9	negative selection	2775567
64580947	64580970	17	+	27260157	MKN45	viability	AAGCAGCTAAGAGGTCTGCCAGG	SMURF2	ENSG00000108854	0.768356151276847	[]	[]	7	hSpCas9	negative selection	2793619
64580794	64580817	17	-	27260157	MKN45	viability	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	0.536610546648472	[]	[]	6	hSpCas9	negative selection	2798602
64580899	64580922	17	-	27260157	MKN45	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	-0.890159474516599	[]	[]	-7	hSpCas9	negative selection	2799670
64562923	64562946	17	+	27260157	RKO	viability	ATACCACTTGCTGTTGCTGTTGG	SMURF2	ENSG00000108854	0.183494099921592	[]	[]	1	hSpCas9	negative selection	2804599
64571882	64571905	17	-	27260157	RKO	viability	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	0.4689233207295	[]	[]	2	hSpCas9	negative selection	2805095
64593450	64593473	17	+	27260157	RKO	viability	TTTGAGGCGGTTGATGGCATTGG	SMURF2	ENSG00000108854	0.944678453465014	[]	[]	8	hSpCas9	negative selection	2810635
64571877	64571900	17	+	27260157	RKO	viability	CTCTGCCTGTTGCCGTATTACGG	SMURF2	ENSG00000108854	1.00130502708688	[]	[]	9	hSpCas9	negative selection	2813094
64580961	64580984	17	+	27260157	RKO	viability	TCTGCCAGGGCTAGAATATTCGG	SMURF2	ENSG00000108854	0.17529103595611	[]	[]	0	hSpCas9	negative selection	2815066
64578550	64578573	17	-	27260157	RKO	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	1.21485188457627	[]	[]	9	hSpCas9	negative selection	2837329
64571891	64571914	17	+	27260157	RKO	viability	GTATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	-1.02393227584287	[]	[]	-8	hSpCas9	negative selection	2837613
64586134	64586157	17	-	27260157	RKO	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	0.413226071542679	[]	[]	2	hSpCas9	negative selection	2841064
64562926	64562949	17	-	27260157	RKO	viability	AGACCAACAGCAACAGCAAGTGG	SMURF2	ENSG00000108854	0.227422716047331	[]	[]	1	hSpCas9	negative selection	2843193
64580965	64580988	17	-	27260157	RKO	viability	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.870068831651144	[]	[]	8	hSpCas9	negative selection	2844557
64571810	64571833	17	+	27260157	RKO	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.170639425530717	[]	[]	0	hSpCas9	negative selection	2846423
64583518	64583541	17	-	27260157	RKO	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	0.951181892254539	[]	[]	8	hSpCas9	negative selection	2846737
64580788	64580811	17	+	27260157	RKO	viability	CCATAGCCTTCTGGTAGGTCTGG	SMURF2	ENSG00000108854	0.228739781613613	[]	[]	1	hSpCas9	negative selection	2847978
64583505	64583528	17	+	27260157	RKO	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.25520798608508	[]	[]	1	hSpCas9	negative selection	2851697
64580947	64580970	17	+	27260157	RKO	viability	AAGCAGCTAAGAGGTCTGCCAGG	SMURF2	ENSG00000108854	1.41599515247197	[]	[]	9	hSpCas9	negative selection	2869749
64580794	64580817	17	-	27260157	RKO	viability	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	0.883508163545654	[]	[]	8	hSpCas9	negative selection	2874732
64580899	64580922	17	-	27260157	RKO	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	-0.493918846276943	[]	[]	-6	hSpCas9	negative selection	2875800
64562923	64562946	17	+	27260157	SF268	viability	ATACCACTTGCTGTTGCTGTTGG	SMURF2	ENSG00000108854	1.02058939339871	[]	[]	9	hSpCas9	negative selection	2880729
64571882	64571905	17	-	27260157	SF268	viability	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	0.0969224222033029	[]	[]	0	hSpCas9	negative selection	2881225
64593450	64593473	17	+	27260157	SF268	viability	TTTGAGGCGGTTGATGGCATTGG	SMURF2	ENSG00000108854	-0.762051117513296	[]	[]	-6	hSpCas9	negative selection	2886765
64571877	64571900	17	+	27260157	SF268	viability	CTCTGCCTGTTGCCGTATTACGG	SMURF2	ENSG00000108854	0.222718590770805	[]	[]	3	hSpCas9	negative selection	2889224
64580961	64580984	17	+	27260157	SF268	viability	TCTGCCAGGGCTAGAATATTCGG	SMURF2	ENSG00000108854	-0.612738411583983	[]	[]	-5	hSpCas9	negative selection	2891196
64578550	64578573	17	-	27260157	SF268	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	1.5124853276995	[]	[]	9	hSpCas9	negative selection	2913459
64571891	64571914	17	+	27260157	SF268	viability	GTATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	-0.523751688807947	[]	[]	-4	hSpCas9	negative selection	2913743
64586134	64586157	17	-	27260157	SF268	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	0.233315967620267	[]	[]	3	hSpCas9	negative selection	2917194
64562926	64562949	17	-	27260157	SF268	viability	AGACCAACAGCAACAGCAAGTGG	SMURF2	ENSG00000108854	0.587170632645593	[]	[]	8	hSpCas9	negative selection	2919323
64580965	64580988	17	-	27260157	SF268	viability	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.582601267067896	[]	[]	8	hSpCas9	negative selection	2920687
64571810	64571833	17	+	27260157	SF268	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.0474006613309632	[]	[]	0	hSpCas9	negative selection	2922553
64583518	64583541	17	-	27260157	SF268	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	0.794789737738156	[]	[]	8	hSpCas9	negative selection	2922867
64580788	64580811	17	+	27260157	SF268	viability	CCATAGCCTTCTGGTAGGTCTGG	SMURF2	ENSG00000108854	-0.11343218809147	[]	[]	-1	hSpCas9	negative selection	2924108
64583505	64583528	17	+	27260157	SF268	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.239022596854193	[]	[]	-2	hSpCas9	negative selection	2927827
64580947	64580970	17	+	27260157	SF268	viability	AAGCAGCTAAGAGGTCTGCCAGG	SMURF2	ENSG00000108854	1.12826584083088	[]	[]	9	hSpCas9	negative selection	2945879
64580794	64580817	17	-	27260157	SF268	viability	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	1.02523531404423	[]	[]	9	hSpCas9	negative selection	2950862
64580899	64580922	17	-	27260157	SF268	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	-1.27500827381049	[]	[]	-7	hSpCas9	negative selection	2951930
64580794	64580817	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	-0.5677310170917226	[3,2]	[3,0]	-7	hSpCas9	positive selection	3022329
64583475	64583498	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	0.801992044365366	[3,2]	[3,6]	9	hSpCas9	positive selection	3022330
64591142	64591165	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGACTTCAAATAGATCAGAGG	SMURF2	ENSG00000108854	-0.1282012775604731	[2,2]	[4,0]	-2	hSpCas9	positive selection	3022331
64571895	64571918	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACGGATCTCCCATCCAGGAGG	SMURF2	ENSG00000108854	0.057611595649775915	[4,3]	[3,3]	1	hSpCas9	positive selection	3022332
64580794	64580817	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	-0.15495635059815954	[3,3]	[2,1]	-2	hSpCas9	positive selection	3090187
64583475	64583498	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.8372410003193107	[3,3]	[1,0]	-9	hSpCas9	positive selection	3090188
64591142	64591165	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGACTTCAAATAGATCAGAGG	SMURF2	ENSG00000108854	-0.87300054389899	[2,2]	[0,0]	-9	hSpCas9	positive selection	3090189
64571895	64571918	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACGGATCTCCCATCCAGGAGG	SMURF2	ENSG00000108854	-0.6921075726377597	[4,4]	[3,0]	-8	hSpCas9	positive selection	3090190
64598399	64598422		-	24336571	A375	resistance to PLX after 7 days	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.06240059733306458	[1,1]	[1,1]	2	hSpCas9	positive selection	3146276
64586086	64586109		-	24336571	A375	resistance to PLX after 7 days	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	-0.031099027129937118	[9,8]	[8,8]	-1	hSpCas9	positive selection	3146277
64598399	64598422		-	24336571	A375	resistance to PLX after 14 days	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.7936732024607864	[2,1]	[1,1]	6	hSpCas9	positive selection	3204069
64586086	64586109		-	24336571	A375	resistance to PLX after 14 days	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	-0.10774027029161937	[6,6]	[2,2]	-1	hSpCas9	positive selection	3204070
64598399	64598422		-	24336571	A375	viability after 7 days	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.629453196570168	[3]	[1,1]	-7	hSpCas9	negative selection	3261862
64586086	64586109		-	24336571	A375	viability after 7 days	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	-0.5003958380935241	[13]	[9,8]	-6	hSpCas9	negative selection	3261863
64598399	64598422		-	24336571	A375	viability after 14 days	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.6686596798183935	[3]	[2,1]	-7	hSpCas9	negative selection	3319655
64586086	64586109		-	24336571	A375	viability after 14 days	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	-0.8278453528929248	[13]	[6,6]	-7	hSpCas9	negative selection	3319656
64583477	64583500	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	-0.16052630344006283	[170,170]	[0,0]	-1	hSpCas9	positive selection	3393986
64586143	64586166	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	0.5708256842626168	[102,102]	[0,0]	3	hSpCas9	positive selection	3393987
64598419	64598442	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.6279695913662254	[98,98]	[0,0]	3	hSpCas9	positive selection	3393988
64580794	64580817	17	-	26780180	HT29	viability (Avana library 4 designs)	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	0.566071313690331	[]	[]	2	hSpCas9	negative selection	3460919
64583475	64583498	17	-	26780180	HT29	viability (Avana library 4 designs)	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	1.19925516830172	[]	[]	5	hSpCas9	negative selection	3460920
64591142	64591165	17	-	26780180	HT29	viability (Avana library 4 designs)	GTTGACTTCAAATAGATCAGAGG	SMURF2	ENSG00000108854	0.914327611311385	[]	[]	3	hSpCas9	negative selection	3460921
64571894	64571917	17	+	26780180	HT29	viability (Avana library 4 designs)	TTACGGATCTCCCATCCAGGAGG	SMURF2	ENSG00000108854	0.881101714750845	[]	[]	3	hSpCas9	negative selection	3460922
64591142	64591165	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGACTTCAAATAGATCAGAGG	SMURF2	ENSG00000108854	-7.74271127264383	[]	[]	-7	hSpCas9	negative selection	3561522
64571894	64571917	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACGGATCTCCCATCCAGGAGG	SMURF2	ENSG00000108854	2.28010592536788	[]	[]	3	hSpCas9	negative selection	3561523
64583475	64583498	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-12.8243418707089	[]	[]	-8	hSpCas9	negative selection	3561524
64580794	64580817	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	0.00545655675536105	[]	[]	0	hSpCas9	negative selection	3561525
64586086	64586109	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	-4.87619987033047	[]	[]	-5	hSpCas9	negative selection	3561526
64571810	64571833	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	3.26701729982014	[]	[]	5	hSpCas9	negative selection	3561527
64591142	64591165	17	-	26780180	A375	viability (Avana lentiGuide)	GTTGACTTCAAATAGATCAGAGG	SMURF2	ENSG00000108854	3.78900063011705	[]	[]	3	hSpCas9	negative selection	3670181
64571894	64571917	17	+	26780180	A375	viability (Avana lentiGuide)	TTACGGATCTCCCATCCAGGAGG	SMURF2	ENSG00000108854	1.81934267792612	[]	[]	2	hSpCas9	negative selection	3670182
64583475	64583498	17	-	26780180	A375	viability (Avana lentiGuide)	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	12.4975644364156	[]	[]	7	hSpCas9	negative selection	3670183
64580794	64580817	17	-	26780180	A375	viability (Avana lentiGuide)	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	-1.35796743220124	[]	[]	-2	hSpCas9	negative selection	3670184
64586086	64586109	17	-	26780180	A375	viability (Avana lentiGuide)	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	2.44549544811717	[]	[]	2	hSpCas9	negative selection	3670185
64571810	64571833	17	+	26780180	A375	viability (Avana lentiGuide)	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	3.82817039659625	[]	[]	4	hSpCas9	negative selection	3670186
64591142	64591165	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGACTTCAAATAGATCAGAGG	SMURF2	ENSG00000108854	-0.6303045726524164	[6]	[4,3]	-7	hSpCas9	positive selection	3778788
64571894	64571917	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACGGATCTCCCATCCAGGAGG	SMURF2	ENSG00000108854	-0.023322830333785183	[5]	[5,4]	0	hSpCas9	positive selection	3778789
64583475	64583498	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.9972790540163685	[7]	[2,3]	-8	hSpCas9	positive selection	3778790
64580794	64580817	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	-0.1704876249803515	[4]	[4,3]	-3	hSpCas9	positive selection	3778791
64586086	64586109	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	-0.4601632494545337	[7]	[5,4]	-6	hSpCas9	positive selection	3778792
64571810	64571833	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.07988969756693642	[5]	[5,6]	2	hSpCas9	positive selection	3778793
64591142	64591165	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGACTTCAAATAGATCAGAGG	SMURF2	ENSG00000108854	-0.40234782126767765	[4]	[2,3]	-5	hSpCas9	positive selection	3887395
64571894	64571917	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACGGATCTCCCATCCAGGAGG	SMURF2	ENSG00000108854	-0.1895213774528109	[5]	[5,2]	-3	hSpCas9	positive selection	3887396
64583475	64583498	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.53764963632368	[4]	[2,1]	-6	hSpCas9	positive selection	3887397
64580794	64580817	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTCCTCCAGACCTACCAGAAGG	SMURF2	ENSG00000108854	0.21807029414976078	[4]	[3,4]	5	hSpCas9	positive selection	3887398
64586086	64586109	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.11773301984294489	[5]	[4,5]	2	hSpCas9	positive selection	3887399
64571810	64571833	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	-0.21499450674044016	[6]	[4,3]	-3	hSpCas9	positive selection	3887400
64598399	64598422	17	-	26780180	A375	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.753443187547397	[]	[]	3	hSpCas9	negative selection	3997490
64583475	64583498	17	-	26780180	A375	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	1.92486790903267	[]	[]	9	hSpCas9	negative selection	3997491
64583477	64583500	17	+	26780180	A375	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.734793965761522	[]	[]	2	hSpCas9	negative selection	3997492
64586143	64586166	17	-	26780180	A375	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	1.55771997872372	[]	[]	8	hSpCas9	negative selection	3997493
64598419	64598442	17	+	26780180	A375	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	1.33231282265529	[]	[]	7	hSpCas9	negative selection	3997494
64586086	64586109	17	-	26780180	A375	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.100878267545763	[]	[]	0	hSpCas9	negative selection	3997495
64598399	64598422	17	-	26780180	HT29	viability (GeCKOv2 library)	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	1.17051367255627	[]	[]	5	hSpCas9	negative selection	4105456
64583475	64583498	17	-	26780180	HT29	viability (GeCKOv2 library)	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	1.245585244735	[]	[]	6	hSpCas9	negative selection	4105457
64583477	64583500	17	+	26780180	HT29	viability (GeCKOv2 library)	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.552756363450179	[]	[]	1	hSpCas9	negative selection	4105458
64586143	64586166	17	-	26780180	HT29	viability (GeCKOv2 library)	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	1.14769841622218	[]	[]	5	hSpCas9	negative selection	4105459
64598419	64598442	17	+	26780180	HT29	viability (GeCKOv2 library)	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.57249235435649	[]	[]	2	hSpCas9	negative selection	4105460
64586086	64586109	17	-	26780180	HT29	viability (GeCKOv2 library)	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.247418030996013	[]	[]	0	hSpCas9	negative selection	4105461
64598399	64598422	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.2863174988057018	[1]	[0,0]	-6	hSpCas9	positive selection	4172366
64586086	64586109	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	-0.27002368971790536	[2]	[1,1]	-6	hSpCas9	positive selection	4172367
64598399	64598422	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.22323878631435845	[2]	[2,0,0,0]	1	hSpCas9	positive selection	4236388
64586086	64586109	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.40722112075896016	[2]	[1,0,3,0]	3	hSpCas9	positive selection	4236389
64583475	64583498	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.27050807464379484	[3]	[1,1]	-5	hSpCas9	positive selection	4299477
64598399	64598422	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.5657986334373868	[1]	[2,1]	9	hSpCas9	positive selection	4299478
64586086	64586109	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.18758405412800414	[3]	[3,1]	4	hSpCas9	positive selection	4299479
64583477	64583500	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.5553033991627864	[2]	[3,3]	9	hSpCas9	positive selection	4363730
64586143	64586166	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.011135266744108016	[2]	[3,1]	0	hSpCas9	positive selection	4363731
64598419	64598442	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.13667627201141186	[2]	[2,0]	-3	hSpCas9	positive selection	4363732
64580965	64580987	17	-	27760321	OCIAML3	viability	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-0.43198169839661243	[704,513]	[319,388]	-4	hSpCas9	negative selection	4441598
64583475	64583497	17	-	27760321	OCIAML3	viability	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.6588834734667408	[8,8]	[0,8]	-6	hSpCas9	negative selection	4441599
64598399	64598421	17	-	27760321	OCIAML3	viability	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.9497475159166707	[171,146]	[247,229]	9	hSpCas9	negative selection	4441600
64598464	64598486	17	+	27760321	OCIAML3	viability	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	0.40212334667922	[391,333]	[300,468]	5	hSpCas9	negative selection	4441601
64571892	64571914	17	+	27760321	OCIAML3	viability	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	0.27741149495414574	[333,312]	[285,333]	3	hSpCas9	negative selection	4441602
64580965	64580987	17	-	27760321	OCIAML2	viability	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-0.10788717999816078	[704,513]	[409,509]	-1	hSpCas9	negative selection	4525061
64583475	64583497	17	-	27760321	OCIAML2	viability	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	1.805618957603536	[8,8]	[9,45]	9	hSpCas9	negative selection	4525062
64598399	64598421	17	-	27760321	OCIAML2	viability	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.5588441399537878	[171,146]	[82,92]	-6	hSpCas9	negative selection	4525063
64598464	64598486	17	+	27760321	OCIAML2	viability	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	-0.3392900210746652	[391,333]	[179,298]	-4	hSpCas9	negative selection	4525064
64571892	64571914	17	+	27760321	OCIAML2	viability	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	0.2183548088025985	[333,312]	[292,319]	3	hSpCas9	negative selection	4525065
64580965	64580987	17	-	27760321	MV411	viability	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.1791226272786025	[704,513]	[472,417]	1	hSpCas9	negative selection	4608524
64583475	64583497	17	-	27760321	MV411	viability	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-2.574976500320316	[8,8]	[0,0]	-9	hSpCas9	negative selection	4608525
64598399	64598421	17	-	27760321	MV411	viability	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.4292663697530865	[171,146]	[0,351]	3	hSpCas9	negative selection	4608526
64598464	64598486	17	+	27760321	MV411	viability	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	-0.542768966259769	[391,333]	[39,349]	-4	hSpCas9	negative selection	4608527
64571892	64571914	17	+	27760321	MV411	viability	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	1.2184912145561384	[333,312]	[590,355]	8	hSpCas9	negative selection	4608528
64580965	64580987	17	-	27760321	HL60	viability	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.11108057193588561	[704,513]	[435,634]	1	hSpCas9	negative selection	4691987
64583475	64583497	17	-	27760321	HL60	viability	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.9148909153202034	[8,8]	[0,6]	-7	hSpCas9	negative selection	4691988
64598399	64598421	17	-	27760321	HL60	viability	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.5591548721484334	[171,146]	[59,117]	-6	hSpCas9	negative selection	4691989
64598464	64598486	17	+	27760321	HL60	viability	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	0.3107864988145992	[391,333]	[369,362]	4	hSpCas9	negative selection	4691990
64571892	64571914	17	+	27760321	HL60	viability	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	-0.33223176961686873	[333,312]	[177,243]	-4	hSpCas9	negative selection	4691991
64580965	64580987	17	-	27760321	HT1080	viability	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-7.50977564478482	[513,400]	[0,0]	-9	hSpCas9	negative selection	4775450
64583475	64583497	17	-	27760321	HT1080	viability	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	4.2286340478716316	[8,6]	[11,111]	9	hSpCas9	negative selection	4775451
64598399	64598421	17	-	27760321	HT1080	viability	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	1.241511625290885	[146,114]	[110,136]	6	hSpCas9	negative selection	4775452
64598464	64598486	17	+	27760321	HT1080	viability	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	1.877494549068768	[333,260]	[424,446]	8	hSpCas9	negative selection	4775453
64571892	64571914	17	+	27760321	HT1080	viability	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	1.3186774530774599	[312,243]	[175,386]	7	hSpCas9	negative selection	4775454
64580965	64580987	17	-	27760321	HT29	viability after 7 days	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.36022405931056783	[513,400]	[1093,484,733]	5	hSpCas9	negative selection	4858913
64583475	64583497	17	-	27760321	HT29	viability after 7 days	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-1.1415113952564866	[8,6]	[10,2,0]	-8	hSpCas9	negative selection	4858914
64598399	64598421	17	-	27760321	HT29	viability after 7 days	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.3524532924293855	[146,114]	[162,134,102]	-5	hSpCas9	negative selection	4858915
64598464	64598486	17	+	27760321	HT29	viability after 7 days	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	-0.23144493512051684	[333,260]	[319,228,423]	-3	hSpCas9	negative selection	4858916
64571892	64571914	17	+	27760321	HT29	viability after 7 days	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	-0.5170233370809567	[312,243]	[341,191,229]	-6	hSpCas9	negative selection	4858917
64580965	64580987	17	-	27760321	HT29	viability after 25 days	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.5495234013081174	[513,400]	[702,600,1020]	6	hSpCas9	negative selection	4942376
64583475	64583497	17	-	27760321	HT29	viability after 25 days	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	0.6341254024888094	[8,6]	[35,0,2]	7	hSpCas9	negative selection	4942377
64598399	64598421	17	-	27760321	HT29	viability after 25 days	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.012522290063481156	[146,114]	[117,176,160]	0	hSpCas9	negative selection	4942378
64598464	64598486	17	+	27760321	HT29	viability after 25 days	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	-0.28393728342748953	[333,260]	[197,248,408]	-3	hSpCas9	negative selection	4942379
64571892	64571914	17	+	27760321	HT29	viability after 25 days	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	-0.2870519650554935	[312,243]	[270,244,265]	-3	hSpCas9	negative selection	4942380
64580965	64580987	17	-	27760321	HT29	viability after 22 days	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.46563031055037424	[513,400]	[844,496,846]	5	hSpCas9	negative selection	5025839
64583475	64583497	17	-	27760321	HT29	viability after 22 days	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-1.9692300153457065	[8,6]	[4,0,0]	-8	hSpCas9	negative selection	5025840
64598399	64598421	17	-	27760321	HT29	viability after 22 days	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.3359709881890256	[146,114]	[120,114,123]	-3	hSpCas9	negative selection	5025841
64598464	64598486	17	+	27760321	HT29	viability after 22 days	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	-0.4233704646966206	[333,260]	[107,349,315]	-4	hSpCas9	negative selection	5025842
64571892	64571914	17	+	27760321	HT29	viability after 22 days	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	-0.5259801807067299	[312,243]	[209,247,212]	-5	hSpCas9	negative selection	5025843
64580965	64580987	17	-	27760321	HT29	viability after 19 days	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.6498154546970965	[513,400]	[899,495,1064]	6	hSpCas9	negative selection	5109302
64583475	64583497	17	-	27760321	HT29	viability after 19 days	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	0.7463647184404332	[8,6]	[47,0,0]	7	hSpCas9	negative selection	5109303
64598399	64598421	17	-	27760321	HT29	viability after 19 days	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.43103122087246803	[146,114]	[77,250,4]	-4	hSpCas9	negative selection	5109304
64598464	64598486	17	+	27760321	HT29	viability after 19 days	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	-0.33586663641383213	[333,260]	[302,450,65]	-3	hSpCas9	negative selection	5109305
64571892	64571914	17	+	27760321	HT29	viability after 19 days	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	0.5227787673659067	[312,243]	[273,186,875]	5	hSpCas9	negative selection	5109306
64580965	64580987	17	-	27760321	HT29	viability after 16 days	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.3077349576673127	[513,400]	[613,658,624]	3	hSpCas9	negative selection	5192765
64583475	64583497	17	-	27760321	HT29	viability after 16 days	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-1.3661977656430064	[8,6]	[8,0,0]	-7	hSpCas9	negative selection	5192766
64598399	64598421	17	-	27760321	HT29	viability after 16 days	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.2633747031558953	[146,114]	[320,156,63]	3	hSpCas9	negative selection	5192767
64598464	64598486	17	+	27760321	HT29	viability after 16 days	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	-0.46409665974172026	[333,260]	[281,268,175]	-5	hSpCas9	negative selection	5192768
64571892	64571914	17	+	27760321	HT29	viability after 16 days	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	-1.0113208095470652	[312,243]	[282,146,45]	-7	hSpCas9	negative selection	5192769
64580965	64580987	17	-	27760321	HT29	viability after 13 days	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.39451730181154704	[513,400]	[881,488,719]	5	hSpCas9	negative selection	5276228
64583475	64583497	17	-	27760321	HT29	viability after 13 days	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-2.806455593993258	[8,6]	[0,1,0]	-9	hSpCas9	negative selection	5276229
64598399	64598421	17	-	27760321	HT29	viability after 13 days	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.1535496385883448	[146,114]	[94,177,136]	-2	hSpCas9	negative selection	5276230
64598464	64598486	17	+	27760321	HT29	viability after 13 days	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	-0.0840782868618255	[333,260]	[178,384,407]	-1	hSpCas9	negative selection	5276231
64571892	64571914	17	+	27760321	HT29	viability after 13 days	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	-0.29197362454085746	[312,243]	[396,159,235]	-4	hSpCas9	negative selection	5276232
64580965	64580987	17	-	27760321	HT29	viability after 10 days	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	0.42470667582070026	[513,400]	[1022,510,758]	6	hSpCas9	negative selection	5359691
64583475	64583497	17	-	27760321	HT29	viability after 10 days	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-1.2213129854103029	[8,6]	[4,6,0]	-8	hSpCas9	negative selection	5359692
64598399	64598421	17	-	27760321	HT29	viability after 10 days	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.6487546576814514	[146,114]	[158,139,16]	-6	hSpCas9	negative selection	5359693
64598464	64598486	17	+	27760321	HT29	viability after 10 days	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	0.023623677686240102	[333,260]	[114,519,498]	0	hSpCas9	negative selection	5359694
64571892	64571914	17	+	27760321	HT29	viability after 10 days	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	-0.3163351611908643	[312,243]	[421,221,193]	-4	hSpCas9	negative selection	5359695
64580965	64580987	17	-	27760321	MOLM13	viability	CATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-0.3211867777416076	[704,513]	[250,290]	-2	hSpCas9	negative selection	5443154
64583475	64583497	17	-	27760321	MOLM13	viability	TATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-2.348919687492721	[8,8]	[0,0]	-8	hSpCas9	negative selection	5443155
64598399	64598421	17	-	27760321	MOLM13	viability	GAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	1.512895798763141	[171,146]	[107,381]	9	hSpCas9	negative selection	5443156
64598464	64598486	17	+	27760321	MOLM13	viability	CCACCTTAGCAAATGGATCAGG	SMURF2	ENSG00000108854	0.962340529987788	[391,333]	[380,411]	6	hSpCas9	negative selection	5443157
64571892	64571914	17	+	27760321	MOLM13	viability	TATTACGGATCTCCCATCCAGG	SMURF2	ENSG00000108854	-0.2608938892268783	[333,312]	[92,202]	-2	hSpCas9	negative selection	5443158
64661981	64662004	17	+	27661255	K562	viability	GGCGCCTCGGCCGCCACGGCCGG	SMURF2	ENSG00000108854	-0.18724010862409624	[371,274]	[245,212]	-5	dCas9-KRAB	negative selection	5513097
64661867	64661890	17	-	27661255	K562	viability	GCCGGGGACATGTCTAACCCCGG	SMURF2	ENSG00000108854	0.07387701750938819	[551,490]	[413,460]	2	dCas9-KRAB	negative selection	5513098
64662010	64662033	17	-	27661255	K562	viability	GCGACGACTCTCGGCACATCCGG	SMURF2	ENSG00000108854	0.12179900876843675	[872,730]	[762,644]	4	dCas9-KRAB	negative selection	5513099
64583475	64583498	17	-	27260156	BXPC3	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.687280195593199	[465]	[313,251,330,314]	-8	hSpCas9	negative selection	5571937
64598399	64598422	17	-	27260156	BXPC3	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.28085302074074514	[117]	[210,99,87,200]	6	hSpCas9	negative selection	5571938
64586086	64586109	17	-	27260156	BXPC3	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.3795184532360816	[485]	[579,561,712,819]	7	hSpCas9	negative selection	5571939
64583477	64583500	17	+	27260156	BXPC3	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.23017499278313966	[358]	[301,447,455,584]	5	hSpCas9	negative selection	5636190
64586143	64586166	17	-	27260156	BXPC3	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.2476259805299873	[380]	[322,299,328,398]	-5	hSpCas9	negative selection	5636191
64598419	64598442	17	+	27260156	BXPC3	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.14871488996803128	[240]	[214,188,199,317]	-3	hSpCas9	negative selection	5636192
64583475	64583498	17	-	27260156	A673	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.3486982659602674	[465]	[557,439,309,464]	-7	hSpCas9	negative selection	5693188
64598399	64598422	17	-	27260156	A673	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.000319945448649106	[117]	[143,147,114,160]	0	hSpCas9	negative selection	5693189
64586086	64586109	17	-	27260156	A673	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.4137567035998327	[485]	[777,774,749,806]	8	hSpCas9	negative selection	5693190
64583477	64583500	17	+	27260156	A673	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.21024976566109913	[358]	[609,397,490,510]	5	hSpCas9	negative selection	5757441
64586143	64586166	17	-	27260156	A673	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.11840012452691712	[380]	[465,342,500,378]	-3	hSpCas9	negative selection	5757442
64598419	64598442	17	+	27260156	A673	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.2911016680292082	[240]	[210,245,251,232]	-6	hSpCas9	negative selection	5757443
64583475	64583498	17	-	27260156	A375	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-1.062091132096185	[465]	[224,370,192,266]	-8	hSpCas9	negative selection	5814439
64598399	64598422	17	-	27260156	A375	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.31899002489420925	[117]	[115,128,142,61]	-4	hSpCas9	negative selection	5814440
64586086	64586109	17	-	27260156	A375	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.331553107807771	[485]	[572,1116,593,634]	5	hSpCas9	negative selection	5814441
64583477	64583500	17	+	27260156	A375	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.5745806150569863	[358]	[732,873,503,441]	8	hSpCas9	negative selection	5878692
64586143	64586166	17	-	27260156	A375	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.13227934475548458	[380]	[332,407,583,308]	-2	hSpCas9	negative selection	5878693
64598419	64598442	17	+	27260156	A375	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.1885018382889876	[240]	[231,292,291,183]	-3	hSpCas9	negative selection	5878694
64583475	64583498	17	-	27260156	COLO741	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.08224990370224401	[465]	[581,492,608]	-2	hSpCas9	negative selection	5935690
64598399	64598422	17	-	27260156	COLO741	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.13049440319289807	[117]	[194,119,180]	2	hSpCas9	negative selection	5935691
64586086	64586109	17	-	27260156	COLO741	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.28908187863260293	[485]	[889,770,633]	6	hSpCas9	negative selection	5935692
64583477	64583500	17	+	27260156	COLO741	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.08983238295184104	[358]	[540,399,523]	2	hSpCas9	negative selection	5999943
64586143	64586166	17	-	27260156	COLO741	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.1459391934483072	[380]	[536,489,309]	-3	hSpCas9	negative selection	5999944
64598419	64598442	17	+	27260156	COLO741	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.00026807536660500286	[240]	[376,327,229]	0	hSpCas9	negative selection	5999945
64583475	64583498	17	-	27260156	CAL120	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.37527064653923486	[465]	[364,534,428]	-5	hSpCas9	negative selection	6056941
64598399	64598422	17	-	27260156	CAL120	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.5224123978945103	[117]	[98,95,110]	-6	hSpCas9	negative selection	6056942
64586086	64586109	17	-	27260156	CAL120	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	-0.07275294314991433	[485]	[724,479,542]	-1	hSpCas9	negative selection	6056943
64583477	64583500	17	+	27260156	CAL120	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.4644398105332976	[358]	[552,591,692]	7	hSpCas9	negative selection	6121194
64586143	64586166	17	-	27260156	CAL120	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.3633219278503036	[380]	[566,289,279]	-5	hSpCas9	negative selection	6121195
64598419	64598442	17	+	27260156	CAL120	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.7186783713755157	[240]	[804,437,287]	9	hSpCas9	negative selection	6121196
64583475	64583498	17	-	27260156	CADOES1	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.7444836418713997	[465]	[239,211,341,239]	-8	hSpCas9	negative selection	6178192
64598399	64598422	17	-	27260156	CADOES1	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.03234694726606513	[117]	[93,143,67,123]	0	hSpCas9	negative selection	6178193
64586086	64586109	17	-	27260156	CADOES1	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.4895110328558513	[485]	[653,641,464,782]	7	hSpCas9	negative selection	6178194
64583477	64583500	17	+	27260156	CADOES1	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.21504218137312756	[358]	[339,415,340,455]	3	hSpCas9	negative selection	6242445
64586143	64586166	17	-	27260156	CADOES1	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.4040551781536613	[380]	[500,143,242,178]	-6	hSpCas9	negative selection	6242446
64598419	64598442	17	+	27260156	CADOES1	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.21919583245701058	[240]	[380,236,198,224]	4	hSpCas9	negative selection	6242447
64583475	64583498	17	-	27260156	EWS502	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.7434688972972853	[465]	[235,334,300,312]	-8	hSpCas9	negative selection	6299443
64598399	64598422	17	-	27260156	EWS502	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.8240034611313418	[117]	[91,52,34,101]	-8	hSpCas9	negative selection	6299444
64586086	64586109	17	-	27260156	EWS502	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.3766636394544382	[485]	[506,825,667,683]	6	hSpCas9	negative selection	6299445
64583477	64583500	17	+	27260156	EWS502	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	-0.1156867936166106	[358]	[339,279,401,387]	-2	hSpCas9	negative selection	6363696
64586143	64586166	17	-	27260156	EWS502	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.21487913556026494	[380]	[309,428,272,379]	-4	hSpCas9	negative selection	6363697
64598419	64598442	17	+	27260156	EWS502	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.24699328676945997	[240]	[202,243,190,221]	-4	hSpCas9	negative selection	6363698
64583475	64583498	17	-	27260156	EW8	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.5869716736045647	[465]	[377,190,201,255]	-8	hSpCas9	negative selection	6420694
64598399	64598422	17	-	27260156	EW8	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.10326454100607219	[117]	[93,58,107,91]	-2	hSpCas9	negative selection	6420695
64586086	64586109	17	-	27260156	EW8	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.4101701574018402	[485]	[425,644,294,753]	7	hSpCas9	negative selection	6420696
64583477	64583500	17	+	27260156	EW8	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.1342381948685113	[358]	[405,386,232,274]	2	hSpCas9	negative selection	6484947
64586143	64586166	17	-	27260156	EW8	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.3006546206888857	[380]	[259,271,251,218]	-5	hSpCas9	negative selection	6484948
64598419	64598442	17	+	27260156	EW8	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.41314762531380356	[240]	[172,143,141,130]	-6	hSpCas9	negative selection	6484949
64583475	64583498	17	-	27260156	CORL105	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.5460485560964032	[465]	[469,363,321,333]	-7	hSpCas9	negative selection	6541945
64598399	64598422	17	-	27260156	CORL105	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.1259537266267161	[117]	[134,112,114,141]	-2	hSpCas9	negative selection	6541946
64586086	64586109	17	-	27260156	CORL105	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.31604994136227815	[485]	[673,638,678,835]	6	hSpCas9	negative selection	6541947
64583477	64583500	17	+	27260156	CORL105	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.16557588972835335	[358]	[503,507,620,276]	3	hSpCas9	negative selection	6606198
64586143	64586166	17	-	27260156	CORL105	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.5017635010045104	[380]	[316,238,388,327]	-7	hSpCas9	negative selection	6606199
64598419	64598442	17	+	27260156	CORL105	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.11422512398980911	[240]	[185,345,220,278]	-2	hSpCas9	negative selection	6606200
64583475	64583498	17	-	27260156	HS294T	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.13437603479081978	[465]	[135,215,140,163]	-2	hSpCas9	negative selection	6663196
64598399	64598422	17	-	27260156	HS294T	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.190827436323324	[117]	[67,24,49,66]	2	hSpCas9	negative selection	6663197
64586086	64586109	17	-	27260156	HS294T	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.38271327832742436	[485]	[225,206,235,326]	5	hSpCas9	negative selection	6663198
64583477	64583500	17	+	27260156	HS294T	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.5402782747582057	[358]	[276,248,113,148]	7	hSpCas9	negative selection	6727449
64586143	64586166	17	-	27260156	HS294T	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.9482461564380967	[380]	[39,74,110,83]	-8	hSpCas9	negative selection	6727450
64598419	64598442	17	+	27260156	HS294T	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.35724549265287586	[240]	[54,96,59,80]	-5	hSpCas9	negative selection	6727451
64583475	64583498	17	-	27260156	HCC44	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.7906479404076295	[465]	[248,234,560,222]	-8	hSpCas9	negative selection	6784447
64598399	64598422	17	-	27260156	HCC44	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.6591503704328248	[117]	[115,35,87,106]	-7	hSpCas9	negative selection	6784448
64586086	64586109	17	-	27260156	HCC44	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.4241413893458327	[485]	[925,575,942,579]	7	hSpCas9	negative selection	6784449
64583477	64583500	17	+	27260156	HCC44	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.6749413116653928	[358]	[614,607,858,547]	9	hSpCas9	negative selection	6848700
64586143	64586166	17	-	27260156	HCC44	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.10295411682523953	[380]	[597,427,407,189]	-2	hSpCas9	negative selection	6848701
64598419	64598442	17	+	27260156	HCC44	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.042617805331848446	[240]	[354,178,433,202]	0	hSpCas9	negative selection	6848702
64583475	64583498	17	-	27260156	G402	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	0.18367890227323339	[465]	[335,420,1438,341]	2	hSpCas9	negative selection	6905698
64598399	64598422	17	-	27260156	G402	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-1.8550298614770195	[117]	[39,16,44,54]	-9	hSpCas9	negative selection	6905699
64586086	64586109	17	-	27260156	G402	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.6728722270872424	[485]	[1080,547,1168,974]	8	hSpCas9	negative selection	6905700
64583477	64583500	17	+	27260156	G402	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.5084707429222939	[358]	[477,787,466,739]	6	hSpCas9	negative selection	6969951
64586143	64586166	17	-	27260156	G402	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.6308492126997985	[380]	[255,368,200,367]	-6	hSpCas9	negative selection	6969952
64598419	64598442	17	+	27260156	G402	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.6146730534676222	[240]	[571,337,313,579]	7	hSpCas9	negative selection	6969953
64583475	64583498	17	-	27260156	L33	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.3164722352126239	[465]	[424,146,201,389]	-6	hSpCas9	negative selection	7026949
64598399	64598422	17	-	27260156	L33	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.3120089996775208	[117]	[101,59,59,241]	6	hSpCas9	negative selection	7026950
64586086	64586109	17	-	27260156	L33	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.5961941791143984	[485]	[609,348,445,769]	9	hSpCas9	negative selection	7026951
64583477	64583500	17	+	27260156	L33	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.07167827437342122	[358]	[421,116,206,469]	1	hSpCas9	negative selection	7091202
64586143	64586166	17	-	27260156	L33	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.0521098549159395	[380]	[361,170,224,332]	-1	hSpCas9	negative selection	7091203
64598419	64598442	17	+	27260156	L33	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.11459862033105184	[240]	[199,108,115,239]	-3	hSpCas9	negative selection	7091204
64583475	64583498	17	-	27260156	K562	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.5510434582916268	[465]	[418,387,134,210]	-6	hSpCas9	negative selection	7148200
64598399	64598422	17	-	27260156	K562	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.6391523580317935	[117]	[342,44,97,172]	7	hSpCas9	negative selection	7148201
64586086	64586109	17	-	27260156	K562	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.5627010958395967	[485]	[883,447,683,549]	7	hSpCas9	negative selection	7148202
64583477	64583500	17	+	27260156	K562	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.3653772952715891	[358]	[419,458,596,192]	4	hSpCas9	negative selection	7212453
64586143	64586166	17	-	27260156	K562	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.03078292437535185	[380]	[312,402,260,345]	0	hSpCas9	negative selection	7212454
64598419	64598442	17	+	27260156	K562	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.2323388988270374	[240]	[138,191,159,227]	-3	hSpCas9	negative selection	7212455
64583475	64583498	17	-	27260156	HT29	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.7137394507102517	[465]	[436,393,309,259]	-8	hSpCas9	negative selection	7269451
64598399	64598422	17	-	27260156	HT29	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.30424275455990735	[117]	[289,185,66,173]	6	hSpCas9	negative selection	7269452
64586086	64586109	17	-	27260156	HT29	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.5650167493026877	[485]	[983,865,939,725]	9	hSpCas9	negative selection	7269453
64583477	64583500	17	+	27260156	HT29	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.29122409736579624	[358]	[542,577,457,554]	6	hSpCas9	negative selection	7333704
64586143	64586166	17	-	27260156	HT29	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.16853654271238033	[380]	[527,504,322,317]	-3	hSpCas9	negative selection	7333705
64598419	64598442	17	+	27260156	HT29	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.3117745585640115	[240]	[245,223,261,212]	-6	hSpCas9	negative selection	7333706
64583475	64583498	17	-	27260156	MHHES1	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.5262383279216151	[465]	[388,417,345,315]	-7	hSpCas9	negative selection	7390702
64598399	64598422	17	-	27260156	MHHES1	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.036945681937559316	[117]	[204,197,117,54]	0	hSpCas9	negative selection	7390703
64586086	64586109	17	-	27260156	MHHES1	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.5075700657569875	[485]	[1130,774,583,670]	8	hSpCas9	negative selection	7390704
64583477	64583500	17	+	27260156	MHHES1	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.7849243968923172	[358]	[835,560,844,563]	9	hSpCas9	negative selection	7454955
64586143	64586166	17	-	27260156	MHHES1	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.18917522733342995	[380]	[531,248,418,316]	-4	hSpCas9	negative selection	7454956
64598419	64598442	17	+	27260156	MHHES1	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.10508129256392573	[240]	[194,307,263,365]	2	hSpCas9	negative selection	7454957
64583475	64583498	17	-	27260156	MEWO	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.6653819950299367	[465]	[330,167,336]	-8	hSpCas9	negative selection	7511953
64598399	64598422	17	-	27260156	MEWO	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.3971606512089165	[117]	[178,64,25]	-7	hSpCas9	negative selection	7511954
64586086	64586109	17	-	27260156	MEWO	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.25989152559092055	[485]	[611,598,434]	5	hSpCas9	negative selection	7511955
64583477	64583500	17	+	27260156	MEWO	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	-0.11330670584581948	[358]	[452,316,188]	-2	hSpCas9	negative selection	7576206
64586143	64586166	17	-	27260156	MEWO	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.038668035651964694	[380]	[522,363,187]	-1	hSpCas9	negative selection	7576207
64598419	64598442	17	+	27260156	MEWO	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.12603737650745583	[240]	[206,356,165]	3	hSpCas9	negative selection	7576208
64583475	64583498	17	-	27260156	LNCAPCLONEFGC	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.9600750103876737	[465]	[147,200,309,224]	-8	hSpCas9	negative selection	7633204
64598399	64598422	17	-	27260156	LNCAPCLONEFGC	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.02848088165597984	[117]	[154,139,78,37]	0	hSpCas9	negative selection	7633205
64586086	64586109	17	-	27260156	LNCAPCLONEFGC	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.5112874615819257	[485]	[567,639,715,598]	7	hSpCas9	negative selection	7633206
64583477	64583500	17	+	27260156	LNCAPCLONEFGC	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.18371510811813652	[358]	[472,264,334,403]	3	hSpCas9	negative selection	7697457
64586143	64586166	17	-	27260156	LNCAPCLONEFGC	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.12291022848784566	[380]	[245,296,422,319]	-2	hSpCas9	negative selection	7697458
64598419	64598442	17	+	27260156	LNCAPCLONEFGC	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.015922948766808775	[240]	[280,113,215,257]	0	hSpCas9	negative selection	7697459
64583475	64583498	17	-	27260156	PANC0327	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.4074606917184681	[465]	[162,574,209,253]	-5	hSpCas9	negative selection	7754455
64598399	64598422	17	-	27260156	PANC0327	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.1589167992197673	[117]	[78,163,158,56]	2	hSpCas9	negative selection	7754456
64586086	64586109	17	-	27260156	PANC0327	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.2396397327215165	[485]	[675,355,414,624]	3	hSpCas9	negative selection	7754457
64583477	64583500	17	+	27260156	PANC0327	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.3663503032285944	[358]	[325,358,450,507]	5	hSpCas9	negative selection	7818708
64586143	64586166	17	-	27260156	PANC0327	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.12566718971880386	[380]	[349,178,359,371]	-2	hSpCas9	negative selection	7818709
64598419	64598442	17	+	27260156	PANC0327	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.20345507948804176	[240]	[241,288,194,253]	3	hSpCas9	negative selection	7818710
64583475	64583498	17	-	27260156	NCIH2009	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-1.1972779391153523	[465]	[314,308,232]	-8	hSpCas9	negative selection	7875706
64598399	64598422	17	-	27260156	NCIH2009	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.32335983688281167	[117]	[220,173,226]	4	hSpCas9	negative selection	7875707
64586086	64586109	17	-	27260156	NCIH2009	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.6392266472773096	[485]	[1086,876,1215]	8	hSpCas9	negative selection	7875708
64583477	64583500	17	+	27260156	NCIH2009	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.08837640632273147	[358]	[542,467,590]	1	hSpCas9	negative selection	7939959
64586143	64586166	17	-	27260156	NCIH2009	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.7243936150039997	[380]	[442,260,286]	-7	hSpCas9	negative selection	7939960
64598419	64598442	17	+	27260156	NCIH2009	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.1501402957154101	[240]	[357,279,282]	-2	hSpCas9	negative selection	7939961
64583475	64583498	17	-	27260156	NCIH1373	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.7909337335921977	[465]	[295,187,485,62]	-7	hSpCas9	negative selection	7996957
64598399	64598422	17	-	27260156	NCIH1373	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.08626922163631612	[117]	[312,164,67,8]	0	hSpCas9	negative selection	7996958
64586086	64586109	17	-	27260156	NCIH1373	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.3508685120391943	[485]	[494,354,778,309]	3	hSpCas9	negative selection	7996959
64583477	64583500	17	+	27260156	NCIH1373	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.2788616153070109	[358]	[457,577,350,145]	2	hSpCas9	negative selection	8061210
64586143	64586166	17	-	27260156	NCIH1373	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-1.8565069527764426	[380]	[181,143,56,24]	-9	hSpCas9	negative selection	8061211
64598419	64598442	17	+	27260156	NCIH1373	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-1.2423709433662362	[240]	[109,46,112,51]	-8	hSpCas9	negative selection	8061212
64583475	64583498	17	-	27260156	PATU8902	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-1.2109959061277382	[465]	[351,42,278,465]	-8	hSpCas9	negative selection	8118208
64598399	64598422	17	-	27260156	PATU8902	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.04981452604284753	[117]	[132,99,54,401]	0	hSpCas9	negative selection	8118209
64586086	64586109	17	-	27260156	PATU8902	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.5542337706384732	[485]	[881,1042,902,1187]	6	hSpCas9	negative selection	8118210
64583477	64583500	17	+	27260156	PATU8902	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.5502194168189576	[358]	[611,765,593,1022]	6	hSpCas9	negative selection	8182461
64586143	64586166	17	-	27260156	PATU8902	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.337175615538552	[380]	[458,161,738,206]	-3	hSpCas9	negative selection	8182462
64598419	64598442	17	+	27260156	PATU8902	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.7234557684172342	[240]	[345,862,454,580]	7	hSpCas9	negative selection	8182463
64583475	64583498	17	-	27260156	PANC1	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.2687575614170123	[465]	[378,574,208,225]	-4	hSpCas9	negative selection	8239459
64598399	64598422	17	-	27260156	PANC1	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.6711049016846276	[117]	[277,146,93,123]	9	hSpCas9	negative selection	8239460
64586086	64586109	17	-	27260156	PANC1	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.6579012573140065	[485]	[688,661,639,635]	9	hSpCas9	negative selection	8239461
64583477	64583500	17	+	27260156	PANC1	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.17648863013631	[358]	[269,436,398,308]	3	hSpCas9	negative selection	8303712
64586143	64586166	17	-	27260156	PANC1	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	0.2434686741388307	[380]	[470,633,311,204]	4	hSpCas9	negative selection	8303713
64598419	64598442	17	+	27260156	PANC1	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.38536546117850157	[240]	[124,270,82,172]	-6	hSpCas9	negative selection	8303714
64583475	64583498	17	-	27260156	PANC0813	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.8414174854664455	[465]	[349,273,320,281]	-8	hSpCas9	negative selection	8360710
64598399	64598422	17	-	27260156	PANC0813	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.32656283512486683	[117]	[129,177,138,239]	5	hSpCas9	negative selection	8360711
64586086	64586109	17	-	27260156	PANC0813	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.4034312985032569	[485]	[831,686,594,902]	6	hSpCas9	negative selection	8360712
64583477	64583500	17	+	27260156	PANC0813	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.23630010637483112	[358]	[549,493,486,461]	4	hSpCas9	negative selection	8424963
64586143	64586166	17	-	27260156	PANC0813	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.7516151929627485	[380]	[447,139,250,241]	-8	hSpCas9	negative selection	8424964
64598419	64598442	17	+	27260156	PANC0813	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.18865142412056501	[240]	[312,166,248,268]	-3	hSpCas9	negative selection	8424965
64583475	64583498	17	-	27260156	RDES	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.8112079146987017	[465]	[222,335,355,315]	-8	hSpCas9	negative selection	8481961
64598399	64598422	17	-	27260156	RDES	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.2076889322758697	[117]	[150,66,238,181]	3	hSpCas9	negative selection	8481962
64586086	64586109	17	-	27260156	RDES	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.31481110545664964	[485]	[664,688,664,752]	5	hSpCas9	negative selection	8481963
64583477	64583500	17	+	27260156	RDES	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.5404127089520988	[358]	[475,606,582,768]	8	hSpCas9	negative selection	8546214
64586143	64586166	17	-	27260156	RDES	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.5922650787339923	[380]	[185,285,402,309]	-7	hSpCas9	negative selection	8546215
64598419	64598442	17	+	27260156	RDES	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.3751446237917573	[240]	[235,190,165,255]	-6	hSpCas9	negative selection	8546216
64583475	64583498	17	-	27260156	PC3	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.7121005680306126	[465]	[207,245,429,311]	-9	hSpCas9	negative selection	8603212
64598399	64598422	17	-	27260156	PC3	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.430397092253227	[117]	[45,44,232,95]	-7	hSpCas9	negative selection	8603213
64586086	64586109	17	-	27260156	PC3	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.4029378109420114	[485]	[514,640,790,649]	8	hSpCas9	negative selection	8603214
64583477	64583500	17	+	27260156	PC3	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	-0.05064862867883291	[358]	[343,279,436,307]	-1	hSpCas9	negative selection	8667465
64586143	64586166	17	-	27260156	PC3	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.29936782895335823	[380]	[190,228,461,444]	-6	hSpCas9	negative selection	8667466
64598419	64598442	17	+	27260156	PC3	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.1741436012263997	[240]	[159,312,389,288]	4	hSpCas9	negative selection	8667467
64583475	64583498	17	-	27260156	PATU8988T	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-1.109528350162078	[465]	[148,270,245,170]	-9	hSpCas9	negative selection	8724463
64598399	64598422	17	-	27260156	PATU8988T	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.8616159003554742	[117]	[97,30,76,39]	-8	hSpCas9	negative selection	8724464
64586086	64586109	17	-	27260156	PATU8988T	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.31899113639634274	[485]	[609,392,666,659]	5	hSpCas9	negative selection	8724465
64583477	64583500	17	+	27260156	PATU8988T	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.5730843492420267	[358]	[644,469,362,589]	8	hSpCas9	negative selection	8788716
64586143	64586166	17	-	27260156	PATU8988T	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	0.06383035006539345	[380]	[492,464,256,328]	1	hSpCas9	negative selection	8788717
64598419	64598442	17	+	27260156	PATU8988T	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.045609903832608656	[240]	[87,281,242,361]	0	hSpCas9	negative selection	8788718
64583475	64583498	17	-	27260156	T47D	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.5144161233081486	[465]	[413,343,350,415]	-8	hSpCas9	negative selection	8845714
64598399	64598422	17	-	27260156	T47D	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.15801582160946714	[117]	[173,139,163,135]	3	hSpCas9	negative selection	8845715
64586086	64586109	17	-	27260156	T47D	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.45129362346897045	[485]	[795,797,766,731]	8	hSpCas9	negative selection	8845716
64583477	64583500	17	+	27260156	T47D	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.24602790956122483	[358]	[557,447,453,529]	5	hSpCas9	negative selection	8909967
64586143	64586166	17	-	27260156	T47D	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.36748169528890073	[380]	[353,293,403,326]	-7	hSpCas9	negative selection	8909968
64598419	64598442	17	+	27260156	T47D	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.03244203395275669	[240]	[326,255,310,255]	0	hSpCas9	negative selection	8909969
64583475	64583498	17	-	27260156	SU8686	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.25743522897998555	[465]	[340,312,487,424]	-4	hSpCas9	negative selection	8966965
64598399	64598422	17	-	27260156	SU8686	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.18022717639579877	[117]	[109,178,133,96]	3	hSpCas9	negative selection	8966966
64586086	64586109	17	-	27260156	SU8686	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.48865839928368837	[485]	[812,564,562,768]	7	hSpCas9	negative selection	8966967
64583477	64583500	17	+	27260156	SU8686	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.5299661773860279	[358]	[391,531,563,588]	8	hSpCas9	negative selection	9031218
64586143	64586166	17	-	27260156	SU8686	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.33741285573530044	[380]	[278,284,302,336]	-5	hSpCas9	negative selection	9031219
64598419	64598442	17	+	27260156	SU8686	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.03998309697432112	[240]	[187,165,197,418]	0	hSpCas9	negative selection	9031220
64583475	64583498	17	-	27260156	SKES1	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.34129256299454785	[465]	[397,419,326,333]	-6	hSpCas9	negative selection	9088216
64598399	64598422	17	-	27260156	SKES1	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.5335039678856814	[117]	[86,114,69,59]	-8	hSpCas9	negative selection	9088217
64586086	64586109	17	-	27260156	SKES1	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.2054353045280785	[485]	[588,502,646,494]	4	hSpCas9	negative selection	9088218
64583477	64583500	17	+	27260156	SKES1	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.019615181042976992	[358]	[438,345,273,394]	0	hSpCas9	negative selection	9152469
64586143	64586166	17	-	27260156	SKES1	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.22294917042627538	[380]	[261,300,383,337]	-5	hSpCas9	negative selection	9152470
64598419	64598442	17	+	27260156	SKES1	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.1901136315563553	[240]	[317,332,229,231]	4	hSpCas9	negative selection	9152471
64583475	64583498	17	-	27260156	TOV112D	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.04502193267171285	[465]	[328,321,361,744]	-1	hSpCas9	negative selection	9209467
64598399	64598422	17	-	27260156	TOV112D	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.1032975855483087	[117]	[169,271,52,53]	2	hSpCas9	negative selection	9209468
64586086	64586109	17	-	27260156	TOV112D	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	-0.06913267702838714	[485]	[610,602,341,348]	-1	hSpCas9	negative selection	9209469
64583477	64583500	17	+	27260156	TOV112D	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	-0.12949819433032284	[358]	[237,585,365,183]	-3	hSpCas9	negative selection	9273720
64586143	64586166	17	-	27260156	TOV112D	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.35265735579629853	[380]	[348,464,272,156]	-6	hSpCas9	negative selection	9273721
64598419	64598442	17	+	27260156	TOV112D	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.1556974413656832	[240]	[188,441,248,231]	3	hSpCas9	negative selection	9273722
64583475	64583498	17	-	27260156	TC71	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.33546930232390765	[465]	[416,365,341,463]	-7	hSpCas9	negative selection	9330718
64598399	64598422	17	-	27260156	TC71	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	0.02773121703806858	[117]	[186,140,86,98]	0	hSpCas9	negative selection	9330719
64586086	64586109	17	-	27260156	TC71	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.4844169788391026	[485]	[752,785,652,724]	9	hSpCas9	negative selection	9330720
64583477	64583500	17	+	27260156	TC71	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.28594122203419436	[358]	[448,400,438,596]	7	hSpCas9	negative selection	9394971
64586143	64586166	17	-	27260156	TC71	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	0.03605585494349045	[380]	[296,482,394,508]	0	hSpCas9	negative selection	9394972
64598419	64598442	17	+	27260156	TC71	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	0.053055640992335285	[240]	[301,298,207,263]	1	hSpCas9	negative selection	9394973
64583475	64583498	17	-	27260156	TC32	viability	ATATAACAAGAACTACGCAATGG	SMURF2	ENSG00000108854	-0.9478677932726485	[465]	[272,57,316,327]	-9	hSpCas9	negative selection	9451969
64598399	64598422	17	-	27260156	TC32	viability	AGAATACGCTTGATCCAAAGTGG	SMURF2	ENSG00000108854	-0.2517507258220695	[117]	[112,47,78,141]	-4	hSpCas9	negative selection	9451970
64586086	64586109	17	-	27260156	TC32	viability	TTTGATAACGATTTACCAGACGG	SMURF2	ENSG00000108854	0.4845461144299912	[485]	[573,660,707,578]	7	hSpCas9	negative selection	9451971
64583477	64583500	17	+	27260156	TC32	viability	ATTGCGTAGTTCTTGTTATATGG	SMURF2	ENSG00000108854	0.2550421447223543	[358]	[350,391,404,449]	4	hSpCas9	negative selection	9516222
64586143	64586166	17	-	27260156	TC32	viability	CTTCAGTCCAGAGACCGAATAGG	SMURF2	ENSG00000108854	-0.18773614076833217	[380]	[330,216,353,381]	-3	hSpCas9	negative selection	9516223
64598419	64598442	17	+	27260156	TC32	viability	TCTTCACAGTATCTGTAGAATGG	SMURF2	ENSG00000108854	-0.12664566883673367	[240]	[178,197,234,216]	-2	hSpCas9	negative selection	9516224
64562866	64562889	17	-	27869803	HPAFII	viability after 27 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	-0.1520789948019471	[395]	[302,90,NaN]	-1	hSpCas9	negative selection	9562398
64571882	64571905	17	-	27869803	HPAFII	viability after 27 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-2.6661522559731847	[89]	[7,6,NaN]	-8	hSpCas9	negative selection	9562399
64578491	64578514	17	-	27869803	HPAFII	viability after 27 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	-3.242344547066609	[17]	[0,0,NaN]	-9	hSpCas9	negative selection	9562400
64580965	64580988	17	-	27869803	HPAFII	viability after 27 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	1.1514134100713664	[51]	[63,57,NaN]	8	hSpCas9	negative selection	9562401
64583505	64583528	17	+	27869803	HPAFII	viability after 27 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.9714457677844166	[157]	[73,15,NaN]	-6	hSpCas9	negative selection	9562402
64586137	64586160	17	-	27869803	HPAFII	viability after 27 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.06887865231787876	[272]	[203,105,NaN]	0	hSpCas9	negative selection	9562403
64562866	64562889	17	-	27869803	HPAFII	viability after 15 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.05334857298350504	[395]	[707,275,NaN]	0	hSpCas9	negative selection	9644847
64571882	64571905	17	-	27869803	HPAFII	viability after 15 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-0.9762360175485654	[89]	[42,52,NaN]	-7	hSpCas9	negative selection	9644848
64578491	64578514	17	-	27869803	HPAFII	viability after 15 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	-0.8036176807176281	[17]	[7,12,NaN]	-7	hSpCas9	negative selection	9644849
64580965	64580988	17	-	27869803	HPAFII	viability after 15 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	1.957560032745928	[51]	[184,236,NaN]	9	hSpCas9	negative selection	9644850
64583505	64583528	17	+	27869803	HPAFII	viability after 15 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.03716003646437893	[157]	[228,125,NaN]	0	hSpCas9	negative selection	9644851
64586137	64586160	17	-	27869803	HPAFII	viability after 15 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	-0.37400578014848684	[272]	[218,230,NaN]	-4	hSpCas9	negative selection	9644852
64562866	64562889	17	-	27869803	ASPC1	viability after 36 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.06604134584976928	[1149]	[287,585,376]	0	hSpCas9	negative selection	9727296
64571882	64571905	17	-	27869803	ASPC1	viability after 36 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	0.4775992494747108	[226]	[102,111,112]	5	hSpCas9	negative selection	9727297
64578491	64578514	17	-	27869803	ASPC1	viability after 36 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	1.7328715351685031	[29]	[0,0,84]	9	hSpCas9	negative selection	9727298
64580965	64580988	17	-	27869803	ASPC1	viability after 36 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-0.4419021948180146	[677]	[457,59,63]	-4	hSpCas9	negative selection	9727299
64583505	64583528	17	+	27869803	ASPC1	viability after 36 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.6622282522458423	[501]	[173,353,285]	6	hSpCas9	negative selection	9727300
64586137	64586160	17	-	27869803	ASPC1	viability after 36 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	-1.5571462240198186	[743]	[111,10,131]	-8	hSpCas9	negative selection	9727301
64562866	64562889	17	-	27869803	PATU8988S	viability after 35 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	-0.009654091625252215	[873]	[198,500,NaN]	0	hSpCas9	negative selection	9809745
64571882	64571905	17	-	27869803	PATU8988S	viability after 35 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-0.9670658905064082	[208]	[68,16,NaN]	-7	hSpCas9	negative selection	9809746
64578491	64578514	17	-	27869803	PATU8988S	viability after 35 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	-0.01797879694321569	[33]	[23,2,NaN]	0	hSpCas9	negative selection	9809747
64580965	64580988	17	-	27869803	PATU8988S	viability after 35 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-0.38931771008137805	[539]	[186,144,NaN]	-4	hSpCas9	negative selection	9809748
64583505	64583528	17	+	27869803	PATU8988S	viability after 35 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.4527960374349764	[362]	[243,155,NaN]	5	hSpCas9	negative selection	9809749
64586137	64586160	17	-	27869803	PATU8988S	viability after 35 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.27514016095186455	[437]	[199,226,NaN]	3	hSpCas9	negative selection	9809750
64562866	64562889	17	-	27869803	PATU8988S	viability after 31 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	-0.17579486185230753	[873]	[121,545,NaN]	-2	hSpCas9	negative selection	9892194
64571882	64571905	17	-	27869803	PATU8988S	viability after 31 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-0.09393872960922733	[208]	[96,53,NaN]	-1	hSpCas9	negative selection	9892195
64578491	64578514	17	-	27869803	PATU8988S	viability after 31 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	1.114811154851317	[33]	[31,25,NaN]	9	hSpCas9	negative selection	9892196
64580965	64580988	17	-	27869803	PATU8988S	viability after 31 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	-0.49441525931666747	[539]	[180,116,NaN]	-5	hSpCas9	negative selection	9892197
64583505	64583528	17	+	27869803	PATU8988S	viability after 31 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.4694225946759406	[362]	[228,163,NaN]	5	hSpCas9	negative selection	9892198
64586137	64586160	17	-	27869803	PATU8988S	viability after 31 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	0.3044305434054056	[437]	[216,213,NaN]	4	hSpCas9	negative selection	9892199
64562866	64562889	17	-	27869803	HPAFII	viability after 35 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.6035639697939617	[395]	[472,114,NaN]	4	hSpCas9	negative selection	9974643
64571882	64571905	17	-	27869803	HPAFII	viability after 35 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-2.738705750498385	[89]	[11,0,NaN]	-8	hSpCas9	negative selection	9974644
64578491	64578514	17	-	27869803	HPAFII	viability after 35 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	-3.187836448445638	[17]	[0,0,NaN]	-8	hSpCas9	negative selection	9974645
64580965	64580988	17	-	27869803	HPAFII	viability after 35 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	1.935789536878377	[51]	[119,78,NaN]	9	hSpCas9	negative selection	9974646
64583505	64583528	17	+	27869803	HPAFII	viability after 35 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.8873606521948192	[157]	[54,29,NaN]	-5	hSpCas9	negative selection	9974647
64586137	64586160	17	-	27869803	HPAFII	viability after 35 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	-0.6953860865140192	[272]	[74,96,NaN]	-4	hSpCas9	negative selection	9974648
64562866	64562889	17	-	27869803	HPAFII	viability after 31 days	CCCAAGGTACAAGCGAGACCTGG	SMURF2	ENSG00000108854	0.24840869895410156	[395]	[397,117,NaN]	1	hSpCas9	negative selection	10057092
64571882	64571905	17	-	27869803	HPAFII	viability after 31 days	GAGATCCGTAATACGGCAACAGG	SMURF2	ENSG00000108854	-2.5746606939574765	[89]	[7,8,NaN]	-8	hSpCas9	negative selection	10057093
64578491	64578514	17	-	27869803	HPAFII	viability after 31 days	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	-3.336553801767055	[17]	[0,0,NaN]	-9	hSpCas9	negative selection	10057094
64580965	64580988	17	-	27869803	HPAFII	viability after 31 days	GCATCCGAATATTCTAGCCCTGG	SMURF2	ENSG00000108854	2.6569973967403966	[51]	[151,218,NaN]	9	hSpCas9	negative selection	10057095
64583505	64583528	17	+	27869803	HPAFII	viability after 31 days	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-1.4033978204185487	[157]	[33,32,NaN]	-7	hSpCas9	negative selection	10057096
64586137	64586160	17	-	27869803	HPAFII	viability after 31 days	TCCAGAGACCGAATAGGCACAGG	SMURF2	ENSG00000108854	-0.09908229310876127	[272]	[143,141,NaN]	0	hSpCas9	negative selection	10057097
64661864	64661887	17	-	28162770	P31FUJ	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	1.504163389751827	[8]	[29]	9	hSpCas9	negative selection	10239560
64580899	64580922	17	-	28162770	P31FUJ	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	-0.03447348796839994	[284]	[326]	0	hSpCas9	negative selection	10239561
64571810	64571833	17	+	28162770	P31FUJ	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.3726243988664933	[139]	[212]	4	hSpCas9	negative selection	10239562
64547690	64547713	17	-	28162770	P31FUJ	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	0.09927384584906651	[169]	[213]	1	hSpCas9	negative selection	10239563
64547605	64547628	17	+	28162770	P31FUJ	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	0.5538932470771325	[210]	[363]	6	hSpCas9	negative selection	10239564
64583518	64583541	17	-	28162770	P31FUJ	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	1.0648783442263063	[71]	[176]	9	hSpCas9	negative selection	10239565
64578550	64578573	17	-	28162770	P31FUJ	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	-0.7633169211131583	[51]	[35]	-5	hSpCas9	negative selection	10239566
64578491	64578514	17	-	28162770	P31FUJ	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.12644751667871817	[144]	[185]	1	hSpCas9	negative selection	10239567
64586134	64586157	17	-	28162770	P31FUJ	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	0.1136482096070528	[69]	[88]	1	hSpCas9	negative selection	10239568
64583505	64583528	17	+	28162770	P31FUJ	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.13714740533592717	[64]	[83]	1	hSpCas9	negative selection	10239569
64661864	64661887	17	-	28162770	TF1	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10408926
64580899	64580922	17	-	28162770	TF1	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	NaN	[NaN]	[382]	1	hSpCas9	negative selection	10408927
64571810	64571833	17	+	28162770	TF1	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10408928
64547690	64547713	17	-	28162770	TF1	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	NaN	[NaN]	[225]	1	hSpCas9	negative selection	10408929
64547605	64547628	17	+	28162770	TF1	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	NaN	[NaN]	[207]	1	hSpCas9	negative selection	10408930
64583518	64583541	17	-	28162770	TF1	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10408931
64578550	64578573	17	-	28162770	TF1	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	NaN	[NaN]	[28]	1	hSpCas9	negative selection	10408932
64578491	64578514	17	-	28162770	TF1	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10408933
64586134	64586157	17	-	28162770	TF1	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10408934
64583505	64583528	17	+	28162770	TF1	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10408935
64661864	64661887	17	-	28162770	SKM1	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	0.17799830197799427	[2]	[5]	1	hSpCas9	negative selection	10578292
64580899	64580922	17	-	28162770	SKM1	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	1.133144066193734	[48]	[189]	9	hSpCas9	negative selection	10578293
64571810	64571833	17	+	28162770	SKM1	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	1.1395241541633587	[37]	[147]	9	hSpCas9	negative selection	10578294
64547690	64547713	17	-	28162770	SKM1	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	-0.1620771396196273	[49]	[78]	-1	hSpCas9	negative selection	10578295
64547605	64547628	17	+	28162770	SKM1	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	1.4822243951318979	[81]	[404]	9	hSpCas9	negative selection	10578296
64583518	64583541	17	-	28162770	SKM1	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.2370391973008492	[19]	[29]	-2	hSpCas9	negative selection	10578297
64578550	64578573	17	-	28162770	SKM1	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	1.0655235727195818	[9]	[36]	8	hSpCas9	negative selection	10578298
64578491	64578514	17	-	28162770	SKM1	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.8624964762500651	[27]	[89]	7	hSpCas9	negative selection	10578299
64586134	64586157	17	-	28162770	SKM1	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	-0.13611028845006845	[22]	[36]	-1	hSpCas9	negative selection	10578300
64583505	64583528	17	+	28162770	SKM1	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-1.6293566200796095	[13]	[7]	-8	hSpCas9	negative selection	10578301
64661864	64661887	17	-	28162770	SKM1	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	0.17799830197799427	[2]	[5]	1	hSpCas9	negative selection	10747658
64580899	64580922	17	-	28162770	SKM1	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	1.133144066193734	[48]	[189]	9	hSpCas9	negative selection	10747659
64571810	64571833	17	+	28162770	SKM1	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	1.1395241541633587	[37]	[147]	9	hSpCas9	negative selection	10747660
64547690	64547713	17	-	28162770	SKM1	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	-0.1620771396196273	[49]	[78]	-1	hSpCas9	negative selection	10747661
64547605	64547628	17	+	28162770	SKM1	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	1.4822243951318979	[81]	[404]	9	hSpCas9	negative selection	10747662
64583518	64583541	17	-	28162770	SKM1	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.2370391973008492	[19]	[29]	-2	hSpCas9	negative selection	10747663
64578550	64578573	17	-	28162770	SKM1	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	1.0655235727195818	[9]	[36]	8	hSpCas9	negative selection	10747664
64578491	64578514	17	-	28162770	SKM1	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.8624964762500651	[27]	[89]	7	hSpCas9	negative selection	10747665
64586134	64586157	17	-	28162770	SKM1	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	-0.13611028845006845	[22]	[36]	-1	hSpCas9	negative selection	10747666
64583505	64583528	17	+	28162770	SKM1	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-1.6293566200796095	[13]	[7]	-8	hSpCas9	negative selection	10747667
64661864	64661887	17	-	28162770	PL21	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	-2.7998603855106805	[15]	[0]	-9	hSpCas9	negative selection	10917024
64580899	64580922	17	-	28162770	PL21	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	-0.9585581315297382	[191]	[42]	-6	hSpCas9	negative selection	10917025
64571810	64571833	17	+	28162770	PL21	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.8216279912355902	[116]	[89]	7	hSpCas9	negative selection	10917026
64547690	64547713	17	-	28162770	PL21	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	0.1523110893987051	[183]	[88]	1	hSpCas9	negative selection	10917027
64547605	64547628	17	+	28162770	PL21	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	-0.5644304410714875	[298]	[87]	-4	hSpCas9	negative selection	10917028
64583518	64583541	17	-	28162770	PL21	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	0.7511547832871387	[85]	[62]	6	hSpCas9	negative selection	10917029
64578550	64578573	17	-	28162770	PL21	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	-1.0683492214365815	[52]	[10]	-6	hSpCas9	negative selection	10917030
64578491	64578514	17	-	28162770	PL21	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.3927846924317162	[76]	[43]	3	hSpCas9	negative selection	10917031
64586134	64586157	17	-	28162770	PL21	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	-0.08743697560726527	[82]	[33]	0	hSpCas9	negative selection	10917032
64583505	64583528	17	+	28162770	PL21	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-1.1217884803980422	[49]	[9]	-6	hSpCas9	negative selection	10917033
64661864	64661887	17	-	28162770	P31FUJ	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	1.504163389751827	[8]	[29]	9	hSpCas9	negative selection	11086390
64580899	64580922	17	-	28162770	P31FUJ	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	-0.03447348796839994	[284]	[326]	0	hSpCas9	negative selection	11086391
64571810	64571833	17	+	28162770	P31FUJ	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.3726243988664933	[139]	[212]	4	hSpCas9	negative selection	11086392
64547690	64547713	17	-	28162770	P31FUJ	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	0.09927384584906651	[169]	[213]	1	hSpCas9	negative selection	11086393
64547605	64547628	17	+	28162770	P31FUJ	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	0.5538932470771325	[210]	[363]	6	hSpCas9	negative selection	11086394
64583518	64583541	17	-	28162770	P31FUJ	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	1.0648783442263063	[71]	[176]	9	hSpCas9	negative selection	11086395
64578550	64578573	17	-	28162770	P31FUJ	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	-0.7633169211131583	[51]	[35]	-5	hSpCas9	negative selection	11086396
64578491	64578514	17	-	28162770	P31FUJ	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.12644751667871817	[144]	[185]	1	hSpCas9	negative selection	11086397
64586134	64586157	17	-	28162770	P31FUJ	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	0.1136482096070528	[69]	[88]	1	hSpCas9	negative selection	11086398
64583505	64583528	17	+	28162770	P31FUJ	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.13714740533592717	[64]	[83]	1	hSpCas9	negative selection	11086399
64661864	64661887	17	-	28162770	OCIAML5	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	-2.4370290715851537	[2]	[0]	-8	hSpCas9	negative selection	11255756
64580899	64580922	17	-	28162770	OCIAML5	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	0.44879990849553564	[137]	[339]	4	hSpCas9	negative selection	11255757
64571810	64571833	17	+	28162770	OCIAML5	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.42311326483188616	[68]	[166]	3	hSpCas9	negative selection	11255758
64547690	64547713	17	-	28162770	OCIAML5	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	0.23773009948664875	[108]	[231]	2	hSpCas9	negative selection	11255759
64547605	64547628	17	+	28162770	OCIAML5	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	-0.00893541948086296	[164]	[295]	0	hSpCas9	negative selection	11255760
64583518	64583541	17	-	28162770	OCIAML5	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.524012373179793	[46]	[58]	-4	hSpCas9	negative selection	11255761
64578550	64578573	17	-	28162770	OCIAML5	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	1.0003762407221453	[17]	[64]	8	hSpCas9	negative selection	11255762
64578491	64578514	17	-	28162770	OCIAML5	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.3867202887231196	[49]	[117]	3	hSpCas9	negative selection	11255763
64586134	64586157	17	-	28162770	OCIAML5	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	-1.437029071585153	[68]	[45]	-7	hSpCas9	negative selection	11255764
64583505	64583528	17	+	28162770	OCIAML5	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.7112040350241475	[38]	[42]	-5	hSpCas9	negative selection	11255765
64661864	64661887	17	-	28162770	EOL1	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	-0.7758919465705576	[25]	[7]	-5	hSpCas9	negative selection	11425122
64580899	64580922	17	-	28162770	EOL1	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	0.44031276193266455	[241]	[172]	4	hSpCas9	negative selection	11425123
64571810	64571833	17	+	28162770	EOL1	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.9492098258048038	[231]	[235]	7	hSpCas9	negative selection	11425124
64547690	64547713	17	-	28162770	EOL1	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	0.7986253315955791	[334]	[306]	7	hSpCas9	negative selection	11425125
64547605	64547628	17	+	28162770	EOL1	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	0.543264399066751	[520]	[399]	5	hSpCas9	negative selection	11425126
64583518	64583541	17	-	28162770	EOL1	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.40168046075045316	[167]	[66]	-3	hSpCas9	negative selection	11425127
64578550	64578573	17	-	28162770	EOL1	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	3.2173295207983807	[39]	[195]	9	hSpCas9	negative selection	11425128
64578491	64578514	17	-	28162770	EOL1	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	1.7337254292349562	[112]	[197]	9	hSpCas9	negative selection	11425129
64586134	64586157	17	-	28162770	EOL1	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	0.7260020921884547	[69]	[60]	6	hSpCas9	negative selection	11425130
64583505	64583528	17	+	28162770	EOL1	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.394033054871755	[51]	[35]	3	hSpCas9	negative selection	11425131
64661864	64661887	17	-	28162770	MOLM13	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	-2.924428041234182	[20]	[1]	-8	hSpCas9	negative selection	11594488
64580899	64580922	17	-	28162770	MOLM13	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	-0.3474731191143915	[270]	[153]	-2	hSpCas9	negative selection	11594489
64571810	64571833	17	+	28162770	MOLM13	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	1.1633514235312856	[133]	[216]	8	hSpCas9	negative selection	11594490
64547690	64547713	17	-	28162770	MOLM13	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	0.25394952523895475	[311]	[268]	1	hSpCas9	negative selection	11594491
64547605	64547628	17	+	28162770	MOLM13	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	-0.39618813052496676	[414]	[227]	-2	hSpCas9	negative selection	11594492
64583518	64583541	17	-	28162770	MOLM13	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.4925822542687839	[143]	[73]	-3	hSpCas9	negative selection	11594493
64578550	64578573	17	-	28162770	MOLM13	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	0.2372764534031626	[87]	[74]	1	hSpCas9	negative selection	11594494
64578491	64578514	17	-	28162770	MOLM13	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.035778368906793756	[169]	[125]	0	hSpCas9	negative selection	11594495
64586134	64586157	17	-	28162770	MOLM13	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	0.23594265349488186	[100]	[85]	1	hSpCas9	negative selection	11594496
64583505	64583528	17	+	28162770	MOLM13	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	1.519728313064197	[40]	[84]	9	hSpCas9	negative selection	11594497
64661864	64661887	17	-	28162770	HEL	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	-2.0202261807220725	[18]	[2]	-8	hSpCas9	negative selection	11763854
64580899	64580922	17	-	28162770	HEL	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	-0.33726969281217706	[214]	[108]	-2	hSpCas9	negative selection	11763855
64571810	64571833	17	+	28162770	HEL	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.1522111331372497	[169]	[120]	1	hSpCas9	negative selection	11763856
64547690	64547713	17	-	28162770	HEL	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	0.4479226550163339	[189]	[165]	4	hSpCas9	negative selection	11763857
64547605	64547628	17	+	28162770	HEL	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	0.41325698587758974	[373]	[318]	3	hSpCas9	negative selection	11763858
64583518	64583541	17	-	28162770	HEL	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	0.2557157088911096	[101]	[77]	2	hSpCas9	negative selection	11763859
64578550	64578573	17	-	28162770	HEL	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	1.4473431430419263	[74]	[130]	9	hSpCas9	negative selection	11763860
64578491	64578514	17	-	28162770	HEL	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	-1.8353084648042872	[116]	[20]	-7	hSpCas9	negative selection	11763861
64586134	64586157	17	-	28162770	HEL	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	-0.5695647717125072	[94]	[40]	-4	hSpCas9	negative selection	11763862
64583505	64583528	17	+	28162770	HEL	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.4276504958910414	[62]	[29]	-3	hSpCas9	negative selection	11763863
64661864	64661887	17	-	28162770	MV411	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	-0.40463914579691806	[10]	[6]	-3	hSpCas9	negative selection	11933220
64580899	64580922	17	-	28162770	MV411	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	1.3496876090307257	[176]	[379]	9	hSpCas9	negative selection	11933221
64571810	64571833	17	+	28162770	MV411	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.26098408262072303	[105]	[106]	2	hSpCas9	negative selection	11933222
64547690	64547713	17	-	28162770	MV411	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	-0.7795294968174943	[215]	[105]	-5	hSpCas9	negative selection	11933223
64547605	64547628	17	+	28162770	MV411	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	0.4747287715320624	[251]	[294]	4	hSpCas9	negative selection	11933224
64583518	64583541	17	-	28162770	MV411	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.7193955852820253	[85]	[43]	-5	hSpCas9	negative selection	11933225
64578550	64578573	17	-	28162770	MV411	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	-0.21553442555977065	[50]	[36]	-2	hSpCas9	negative selection	11933226
64578491	64578514	17	-	28162770	MV411	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	-0.46197232086286955	[120]	[73]	-3	hSpCas9	negative selection	11933227
64586134	64586157	17	-	28162770	MV411	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	1.1919424381910717	[52]	[101]	9	hSpCas9	negative selection	11933228
64583505	64583528	17	+	28162770	MV411	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.7943826249118517	[34]	[16]	-5	hSpCas9	negative selection	11933229
64661864	64661887	17	-	28162770	MONOMAC1	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	-0.04503375361450335	[8]	[9]	0	hSpCas9	negative selection	12102586
64580899	64580922	17	-	28162770	MONOMAC1	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	1.2530703187465415	[126]	[346]	9	hSpCas9	negative selection	12102587
64571810	64571833	17	+	28162770	MONOMAC1	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	-0.07885542071123941	[81]	[88]	0	hSpCas9	negative selection	12102588
64547690	64547713	17	-	28162770	MONOMAC1	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	-1.0533013695981044	[104]	[57]	-7	hSpCas9	negative selection	12102589
64547605	64547628	17	+	28162770	MONOMAC1	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	-0.5172151599969563	[205]	[164]	-4	hSpCas9	negative selection	12102590
64583518	64583541	17	-	28162770	MONOMAC1	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.19703684705955382	[37]	[37]	-2	hSpCas9	negative selection	12102591
64578550	64578573	17	-	28162770	MONOMAC1	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	-0.956028747555759	[21]	[12]	-6	hSpCas9	negative selection	12102592
64578491	64578514	17	-	28162770	MONOMAC1	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	-0.24678988225665344	[58]	[56]	-2	hSpCas9	negative selection	12102593
64586134	64586157	17	-	28162770	MONOMAC1	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	2.2453716237354295	[61]	[336]	9	hSpCas9	negative selection	12102594
64583505	64583528	17	+	28162770	MONOMAC1	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-0.864461507972683	[26]	[16]	-6	hSpCas9	negative selection	12102595
64661864	64661887	17	-	28162770	OCIAML2	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	0.11433267547899462	[1]	[11]	1	hSpCas9	negative selection	12271952
64580899	64580922	17	-	28162770	OCIAML2	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	0.46999162767890723	[30]	[237]	4	hSpCas9	negative selection	12271953
64571810	64571833	17	+	28162770	OCIAML2	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.3367250968154428	[24]	[174]	3	hSpCas9	negative selection	12271954
64547690	64547713	17	-	28162770	OCIAML2	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	0.09068140741434955	[40]	[241]	0	hSpCas9	negative selection	12271955
64547605	64547628	17	+	28162770	OCIAML2	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	0.10384030166135272	[45]	[273]	1	hSpCas9	negative selection	12271956
64583518	64583541	17	-	28162770	OCIAML2	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-0.9445610135745734	[24]	[71]	-6	hSpCas9	negative selection	12271957
64578550	64578573	17	-	28162770	OCIAML2	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	1.595459365215611	[3]	[66]	9	hSpCas9	negative selection	12271958
64578491	64578514	17	-	28162770	OCIAML2	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.5882638638114075	[17]	[149]	6	hSpCas9	negative selection	12271959
64586134	64586157	17	-	28162770	OCIAML2	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	-0.1905219060494261	[13]	[67]	-1	hSpCas9	negative selection	12271960
64583505	64583528	17	+	28162770	OCIAML2	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	0.1440800188730469	[7]	[48]	1	hSpCas9	negative selection	12271961
64661864	64661887	17	-	28162770	OCIAML3	viability	GGGGACATGTCTAACCCCGGAGG	SMURF2	ENSG00000108854	2.247294613656779	[8]	[128]	9	hSpCas9	negative selection	12441318
64580899	64580922	17	-	28162770	OCIAML3	viability	GGAACAAATGGTGCAACATGTGG	SMURF2	ENSG00000108854	0.24249362739295743	[55]	[199]	2	hSpCas9	negative selection	12441319
64571810	64571833	17	+	28162770	OCIAML3	viability	TGCAAGTTAGCAGACAGCCGAGG	SMURF2	ENSG00000108854	0.9785711359411606	[38]	[231]	8	hSpCas9	negative selection	12441320
64547690	64547713	17	-	28162770	OCIAML3	viability	CAAATGGTTCTGGAAAGCTGTGG	SMURF2	ENSG00000108854	-0.6079468312820369	[51]	[102]	-5	hSpCas9	negative selection	12441321
64547605	64547628	17	+	28162770	OCIAML3	viability	AATGCTTTGAAGCCCTGCAGAGG	SMURF2	ENSG00000108854	-0.4581242122423902	[80]	[177]	-4	hSpCas9	negative selection	12441322
64583518	64583541	17	-	28162770	OCIAML3	viability	GAAGAAAGGAGAACCGCCTCTGG	SMURF2	ENSG00000108854	-1.2154960170704332	[19]	[25]	-7	hSpCas9	negative selection	12441323
64578550	64578573	17	-	28162770	OCIAML3	viability	GAGGACAACGCAACAAGGCCAGG	SMURF2	ENSG00000108854	0.7055526415347448	[12]	[63]	6	hSpCas9	negative selection	12441324
64578491	64578514	17	-	28162770	OCIAML3	viability	GGCATGATCCAAGAGTGCCCAGG	SMURF2	ENSG00000108854	0.4763816875672348	[29]	[125]	4	hSpCas9	negative selection	12441325
64586134	64586157	17	-	28162770	OCIAML3	viability	AGAGACCGAATAGGCACAGGAGG	SMURF2	ENSG00000108854	2.293517630417424	[9]	[147]	9	hSpCas9	negative selection	12441326
64583505	64583528	17	+	28162770	OCIAML3	viability	ATACTGGATTCTTCCAGAGGCGG	SMURF2	ENSG00000108854	-1.5940076403241634	[13]	[13]	-8	hSpCas9	negative selection	12441327