Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:25992
• Symbol:SNED1
• Description:sushi, nidogen and EGF like domains 1

DataSource: http://genomecrispr.dkfz.de/#!/results/SNED1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
241071864	241071887	2	-	26472758	Jiyoye	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.3076397079549589	[389]	[363]	2	hSpCas9	negative selection	152747
240998917	240998940	2	-	26472758	Jiyoye	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	1.733161692967589	[70]	[177]	8	hSpCas9	negative selection	152748
241071864	241071887	2	-	26472758	KBM7	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.13582048123921964	[1104,1001]	[625,470]	1	hSpCas9	negative selection	343865
240998917	240998940	2	-	26472758	KBM7	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	0.15505953583093168	[723,454]	[360,250]	1	hSpCas9	negative selection	343866
241071864	241071887	2	-	26472758	Raji	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.5638126658493734	[480]	[164]	5	hSpCas9	negative selection	534983
240998917	240998940	2	-	26472758	Raji	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	-0.35590040875930434	[374]	[67]	-3	hSpCas9	negative selection	534984
241071864	241071887	2	-	26472758	K562	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	-0.1136521760116096	[868]	[677]	-1	hSpCas9	negative selection	726101
240998917	240998940	2	-	26472758	K562	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	0.0029805506394523507	[609]	[515]	0	hSpCas9	negative selection	726102
240999013	240999036	2	-	26627737	DLD1	viability	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.618362424791883	[475]	[175,65,53]	-6	hSpCas9	negative selection	811210
240999013	240999036	2	-	26627737	GBM cells	viability after 5 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.3975765292126214	[154]	[114,103]	6	hSpCas9	negative selection	893525
240999013	240999036	2	-	26627737	GBM cells	viability after 13 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	1.003087057969676	[154]	[183,155]	9	hSpCas9	negative selection	975840
240999013	240999036	2	-	26627737	GBM cells	viability after 21 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.8791987387675316	[154]	[180,130]	8	hSpCas9	negative selection	1058155
240999013	240999036	2	-	26627737	RPE1	viability after 9 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.32364713990412863	[554]	[130,328]	2	hSpCas9	negative selection	1140470
240999013	240999036	2	-	26627737	RPE1	viability after 12 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.3708051074029397	[554]	[142,85]	-3	hSpCas9	negative selection	1222785
240999013	240999036	2	-	26627737	RPE1	viability after 15 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.06948036563311166	[554]	[114,182]	0	hSpCas9	negative selection	1305100
240999013	240999036	2	-	26627737	RPE1	viability after 18 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.10655454992537283	[554]	[156,119]	0	hSpCas9	negative selection	1387415
240999013	240999036	2	-	26627737	HeLa	viability after 8 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.08690844425885973	[453]	[250,189,134]	-1	hSpCas9	negative selection	1469730
240999013	240999036	2	-	26627737	HeLa	viability after 12 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.4396633662446852	[453]	[27,126,257]	-4	hSpCas9	negative selection	1552045
240999013	240999036	2	-	26627737	HeLa	viability after 15 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.14027177100976723	[453]	[242,92,165]	-1	hSpCas9	negative selection	1634360
240999013	240999036	2	-	26627737	HeLa	viability after 18 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.09950229429020385	[453]	[169,79,165]	-1	hSpCas9	negative selection	1716675
240999013	240999036	2	-	26627737	HCT116	viability after 6 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-1.5924073128823206	[424]	[16,24]	-7	hSpCas9	negative selection	1798990
240999013	240999036	2	-	26627737	HCT116	viability after 8 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	1.4921611203892742	[99]	[126,138,197]	9	hSpCas9	negative selection	1881305
240999013	240999036	2	-	26627737	HCT116	viability after 9 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.27293565236920625	[424]	[135,137]	2	hSpCas9	negative selection	1963620
240999013	240999036	2	-	26627737	HCT116	viability after 12 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	1.2191813167485495	[99]	[119,152,94]	8	hSpCas9	negative selection	2045935
240999013	240999036	2	-	26627737	HCT116	viability after 15 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	1.1091665913320212	[99]	[138,68,164]	8	hSpCas9	negative selection	2128250
240999013	240999036	2	-	26627737	HCT116	viability after 18 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	1.3523729700819345	[99]	[212,97,57]	8	hSpCas9	negative selection	2210565
241005444	241005467	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTGGGAGGCTGAGGCAGGCAGG	SNED1	ENSG00000162804	0.6597088728489087	[159,20]	[40,18]	3	dCas9-VP64	positive selection	2472694
241005444	241005467	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTGGGAGGCTGAGGCAGGCAGG	SNED1	ENSG00000162804	0.628589961662267	[19,33]	[6,18]	4	dCas9-VP64	positive selection	2567949
240998917	240998940	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	-0.6150345796186557	[3,3]	[0,2]	-7	hSpCas9	positive selection	3022419
240998917	240998940	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	-0.16246955954032327	[3,3]	[3,1]	-2	hSpCas9	positive selection	3090277
240998917	240998940	2	-	26780180	HT29	viability (Avana library 4 designs)	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	3.02577082006245	[]	[]	8	hSpCas9	negative selection	3461015
240998917	240998940	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	-1.10291155851777	[]	[]	-1	hSpCas9	negative selection	3561660
240998917	240998940	2	-	26780180	A375	viability (Avana lentiGuide)	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	5.18728597486746	[]	[]	4	hSpCas9	negative selection	3670319
240998917	240998940	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	0.06374129232347539	[4]	[4,4]	1	hSpCas9	positive selection	3778926
240998917	240998940	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	-0.42786524979528257	[5]	[2,3]	-5	hSpCas9	positive selection	3887533
240999013	240999035	2	-	27760321	OCIAML3	viability	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.6934655186019183	[224,196]	[126,68]	-6	hSpCas9	negative selection	4441721
240999013	240999035	2	-	27760321	OCIAML2	viability	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.8713224998625927	[224,196]	[289,339]	9	hSpCas9	negative selection	4525184
240999013	240999035	2	-	27760321	MV411	viability	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.5496878999457065	[224,196]	[170,251]	4	hSpCas9	negative selection	4608647
240999013	240999035	2	-	27760321	HL60	viability	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-1.072300981552777	[224,196]	[107,53]	-8	hSpCas9	negative selection	4692110
240999013	240999035	2	-	27760321	HT1080	viability	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.6048576835061159	[196,153]	[55,34]	-3	hSpCas9	negative selection	4775573
240999013	240999035	2	-	27760321	HT29	viability after 7 days	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.10013965946501258	[196,153]	[181,163,278]	-1	hSpCas9	negative selection	4859036
240999013	240999035	2	-	27760321	HT29	viability after 25 days	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.44891295429948475	[196,153]	[399,242,157]	5	hSpCas9	negative selection	4942499
240999013	240999035	2	-	27760321	HT29	viability after 22 days	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.13504700385943802	[196,153]	[304,172,71]	-1	hSpCas9	negative selection	5025962
240999013	240999035	2	-	27760321	HT29	viability after 19 days	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.8481157216211799	[196,153]	[143,112,81]	-6	hSpCas9	negative selection	5109425
240999013	240999035	2	-	27760321	HT29	viability after 16 days	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.03450942535256485	[196,153]	[274,174,160]	0	hSpCas9	negative selection	5192888
240999013	240999035	2	-	27760321	HT29	viability after 13 days	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.009378431346890315	[196,153]	[330,165,114]	0	hSpCas9	negative selection	5276351
240999013	240999035	2	-	27760321	HT29	viability after 10 days	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.005933584774483247	[196,153]	[188,291,181]	0	hSpCas9	negative selection	5359814
240999013	240999035	2	-	27760321	MOLM13	viability	TCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-1.2169211729562948	[224,196]	[42,57]	-6	hSpCas9	negative selection	5443277
240998923	240998946	2	-	27661255	K562	viability	GGCGCCGAACGGGTAGAAGTCGG	SNED1	ENSG00000162804	0.12339136150198232	[698,647]	[595,578]	4	dCas9-KRAB	negative selection	5513188
240999018	240999041	2	-	27661255	K562	viability	GAGTGCTCGGCACCGAAGAACGG	SNED1	ENSG00000162804	0.2666141487149696	[614,822]	[797,592]	8	dCas9-KRAB	negative selection	5513189
240999040	240999063	2	-	27661255	K562	viability	GGGGTTACTCACGTAGAGTCCGG	SNED1	ENSG00000162804	0.16634878865881383	[662,762]	[751,539]	6	dCas9-KRAB	negative selection	5513190
240999013	240999036	2	-	27869803	HPAFII	viability after 27 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.10085396675939577	[212]	[148,95,NaN]	0	hSpCas9	negative selection	9574264
240999013	240999036	2	-	27869803	HPAFII	viability after 15 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.8464511363838223	[212]	[85,152,NaN]	-7	hSpCas9	negative selection	9656713
240999013	240999036	2	-	27869803	ASPC1	viability after 36 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	-0.08253125793565741	[361]	[190,40,129]	-1	hSpCas9	negative selection	9739162
240999013	240999036	2	-	27869803	PATU8988S	viability after 35 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.09329345476300077	[290]	[137,111,NaN]	1	hSpCas9	negative selection	9821611
240999013	240999036	2	-	27869803	PATU8988S	viability after 31 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.10134413278949883	[290]	[116,133,NaN]	1	hSpCas9	negative selection	9904060
240999013	240999036	2	-	27869803	HPAFII	viability after 35 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.46117956478223443	[212]	[218,68,NaN]	3	hSpCas9	negative selection	9986509
240999013	240999036	2	-	27869803	HPAFII	viability after 31 days	CTCGGCACCGAAGAACGGGAAGG	SNED1	ENSG00000162804	0.15347905441345164	[212]	[198,60,NaN]	1	hSpCas9	negative selection	10068958
241071864	241071887	2	-	28162770	P31FUJ	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.2788236843650429	[342]	[488]	3	hSpCas9	negative selection	10239801
240998917	240998940	2	-	28162770	P31FUJ	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	0.1277287296967311	[235]	[302]	1	hSpCas9	negative selection	10239802
241071864	241071887	2	-	28162770	TF1	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	NaN	[NaN]	[580]	1	hSpCas9	negative selection	10409167
240998917	240998940	2	-	28162770	TF1	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	NaN	[NaN]	[180]	1	hSpCas9	negative selection	10409168
241071864	241071887	2	-	28162770	SKM1	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.3183709583425467	[136]	[301]	3	hSpCas9	negative selection	10578533
240998917	240998940	2	-	28162770	SKM1	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	-1.1388588033619458	[70]	[56]	-7	hSpCas9	negative selection	10578534
241071864	241071887	2	-	28162770	SKM1	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.3183709583425467	[136]	[301]	3	hSpCas9	negative selection	10747899
240998917	240998940	2	-	28162770	SKM1	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	-1.1388588033619458	[70]	[56]	-7	hSpCas9	negative selection	10747900
241071864	241071887	2	-	28162770	PL21	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	-0.9514916024126504	[430]	[96]	-6	hSpCas9	negative selection	10917265
240998917	240998940	2	-	28162770	PL21	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	-0.1672314511592094	[257]	[99]	-1	hSpCas9	negative selection	10917266
241071864	241071887	2	-	28162770	P31FUJ	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.2788236843650429	[342]	[488]	3	hSpCas9	negative selection	11086631
240998917	240998940	2	-	28162770	P31FUJ	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	0.1277287296967311	[235]	[302]	1	hSpCas9	negative selection	11086632
241071864	241071887	2	-	28162770	OCIAML5	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.40189592947332065	[225]	[538]	3	hSpCas9	negative selection	11255997
240998917	240998940	2	-	28162770	OCIAML5	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	0.7567426718115269	[119]	[365]	6	hSpCas9	negative selection	11255998
241071864	241071887	2	-	28162770	EOL1	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	-0.13614816011701958	[800]	[383]	-1	hSpCas9	negative selection	11425363
240998917	240998940	2	-	28162770	EOL1	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	1.110483545752099	[457]	[520]	8	hSpCas9	negative selection	11425364
241071864	241071887	2	-	28162770	MOLM13	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.9100926330643051	[604]	[821]	7	hSpCas9	negative selection	11594729
240998917	240998940	2	-	28162770	MOLM13	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	0.6941652373682548	[317]	[371]	5	hSpCas9	negative selection	11594730
241071864	241071887	2	-	28162770	HEL	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.30570384472278644	[527]	[417]	2	hSpCas9	negative selection	11764095
240998917	240998940	2	-	28162770	HEL	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	0.5203167291050248	[294]	[270]	4	hSpCas9	negative selection	11764096
241071864	241071887	2	-	28162770	MV411	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	-0.08625399342042495	[430]	[341]	0	hSpCas9	negative selection	11933461
240998917	240998940	2	-	28162770	MV411	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	-1.3616710372700833	[240]	[78]	-7	hSpCas9	negative selection	11933462
241071864	241071887	2	-	28162770	MONOMAC1	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.5700982267452659	[264]	[450]	5	hSpCas9	negative selection	12102827
240998917	240998940	2	-	28162770	MONOMAC1	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	-0.8344667676748455	[167]	[107]	-6	hSpCas9	negative selection	12102828
241071864	241071887	2	-	28162770	OCIAML2	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	0.16919461051351314	[85]	[535]	1	hSpCas9	negative selection	12272193
240998917	240998940	2	-	28162770	OCIAML2	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	0.425534363773299	[35]	[267]	4	hSpCas9	negative selection	12272194
241071864	241071887	2	-	28162770	OCIAML3	viability	GCACTCACGTGATCTCACGGTGG	SNED1	ENSG00000162804	-0.33982415207263506	[108]	[259]	-3	hSpCas9	negative selection	12441559
240998917	240998940	2	-	28162770	OCIAML3	viability	GAACGGGTAGAAGTCGGCAAGGG	SNED1	ENSG00000162804	-1.2267986661359345	[68]	[88]	-7	hSpCas9	negative selection	12441560