Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:54861
• Symbol:SNRK
• Description:SNF related kinase

DataSource: http://genomecrispr.dkfz.de/#!/results/SNRK

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
43303202	43303225	3	+	26472758	Jiyoye	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	0.44385604483234187	[232]	[238]	3	hSpCas9	negative selection	152785
43332282	43332305	3	-	26472758	Jiyoye	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	0.4818141823986291	[112]	[118]	3	hSpCas9	negative selection	152786
43303708	43303731	3	+	26472758	Jiyoye	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	2.585512622764386	[37]	[171]	9	hSpCas9	negative selection	152787
43303269	43303292	3	+	26472758	Jiyoye	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	-0.4932889449432122	[195]	[104]	-4	hSpCas9	negative selection	152788
43303527	43303550	3	+	26472758	Jiyoye	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	0.5735337679279933	[179]	[201]	4	hSpCas9	negative selection	152789
43303286	43303309	3	-	26472758	Jiyoye	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.4419407996665501	[204]	[209]	3	hSpCas9	negative selection	152790
43332216	43332239	3	-	26472758	Jiyoye	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	-0.8085533095495638	[287]	[123]	-5	hSpCas9	negative selection	152791
43340354	43340377	3	-	26472758	Jiyoye	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.6888070062169972	[166]	[202]	5	hSpCas9	negative selection	152792
43340304	43340327	3	+	26472758	Jiyoye	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	0.6014442019279331	[110]	[126]	4	hSpCas9	negative selection	152793
43303771	43303794	3	+	26472758	Jiyoye	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	0.6155409175700357	[250]	[289]	4	hSpCas9	negative selection	152794
43303202	43303225	3	+	26472758	KBM7	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	0.7124030072419415	[919,845]	[752,615]	7	hSpCas9	negative selection	343903
43332282	43332305	3	-	26472758	KBM7	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	-0.023039857291009547	[223,324]	[204,62]	0	hSpCas9	negative selection	343904
43303708	43303731	3	+	26472758	KBM7	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.7698379104252872	[530,460]	[354,433]	8	hSpCas9	negative selection	343905
43303269	43303292	3	+	26472758	KBM7	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.5118106946918083	[876,369]	[446,362]	5	hSpCas9	negative selection	343906
43303527	43303550	3	+	26472758	KBM7	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	0.07495579094124927	[936,554]	[510,227]	0	hSpCas9	negative selection	343907
43303286	43303309	3	-	26472758	KBM7	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.24801280802908482	[327,277]	[166,169]	2	hSpCas9	negative selection	343908
43332216	43332239	3	-	26472758	KBM7	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.4716898235823258	[862,897]	[472,671]	5	hSpCas9	negative selection	343909
43340354	43340377	3	-	26472758	KBM7	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.8553040680905004	[779,559]	[522,598]	8	hSpCas9	negative selection	343910
43340304	43340327	3	+	26472758	KBM7	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	0.27204221193021816	[486,540]	[269,316]	3	hSpCas9	negative selection	343911
43303771	43303794	3	+	26472758	KBM7	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	0.19787806852680578	[1397,1326]	[954,540]	2	hSpCas9	negative selection	343912
43303202	43303225	3	+	26472758	Raji	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	-0.13714005582815614	[634]	[133]	-1	hSpCas9	negative selection	535021
43332282	43332305	3	-	26472758	Raji	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	0.6644400395248711	[86]	[31]	6	hSpCas9	negative selection	535022
43303708	43303731	3	+	26472758	Raji	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	1.1472762624971122	[213]	[109]	8	hSpCas9	negative selection	535023
43303269	43303292	3	+	26472758	Raji	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.43025119072457624	[306]	[95]	4	hSpCas9	negative selection	535024
43303527	43303550	3	+	26472758	Raji	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	0.7609331213521682	[355]	[139]	7	hSpCas9	negative selection	535025
43303286	43303309	3	-	26472758	Raji	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.6412984305043632	[162]	[58]	6	hSpCas9	negative selection	535026
43332216	43332239	3	-	26472758	Raji	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.3186043425711358	[462]	[133]	3	hSpCas9	negative selection	535027
43340354	43340377	3	-	26472758	Raji	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	1.1369278109876149	[289]	[147]	8	hSpCas9	negative selection	535028
43340304	43340327	3	+	26472758	Raji	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	0.5140087948362432	[343]	[113]	5	hSpCas9	negative selection	535029
43303771	43303794	3	+	26472758	Raji	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	-0.43886185777470277	[624]	[106]	-4	hSpCas9	negative selection	535030
43303202	43303225	3	+	26472758	K562	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	-0.1134548835516197	[700]	[546]	-1	hSpCas9	negative selection	726139
43332282	43332305	3	-	26472758	K562	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	-0.20250283263218294	[243]	[178]	-1	hSpCas9	negative selection	726140
43303708	43303731	3	+	26472758	K562	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.33398411246243304	[483]	[514]	2	hSpCas9	negative selection	726141
43303269	43303292	3	+	26472758	K562	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.8837083907769598	[442]	[689]	7	hSpCas9	negative selection	726142
43303527	43303550	3	+	26472758	K562	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	-0.14899872950864274	[573]	[436]	-1	hSpCas9	negative selection	726143
43303286	43303309	3	-	26472758	K562	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	1.2284418751166788	[226]	[448]	9	hSpCas9	negative selection	726144
43332216	43332239	3	-	26472758	K562	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	-0.6089243286199333	[756]	[418]	-4	hSpCas9	negative selection	726145
43340354	43340377	3	-	26472758	K562	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.6120788058600584	[502]	[648]	5	hSpCas9	negative selection	726146
43340304	43340327	3	+	26472758	K562	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	0.7095650752433293	[480]	[663]	6	hSpCas9	negative selection	726147
43303771	43303794	3	+	26472758	K562	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	-0.5315720234818222	[1273]	[743]	-3	hSpCas9	negative selection	726148
43303286	43303309	3	-	26627737	DLD1	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.2622658383920925	[555]	[160,133,139]	-3	hSpCas9	negative selection	821727
43332191	43332214	3	-	26627737	DLD1	viability	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.32499780601318584	[697]	[293,338,200]	3	hSpCas9	negative selection	821728
43340440	43340463	3	+	26627737	DLD1	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.6809816170335176	[819]	[349,400,471]	6	hSpCas9	negative selection	821729
43340490	43340513	3	-	26627737	DLD1	viability	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.5776493989215896	[349]	[153,16,49]	-5	hSpCas9	negative selection	821730
43347951	43347974	3	+	26627737	DLD1	viability	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	-0.15135317273501236	[2078]	[485,734,546]	-2	hSpCas9	negative selection	821731
43303286	43303309	3	-	26627737	GBM cells	viability after 5 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.5935008667813398	[303]	[235,255]	8	hSpCas9	negative selection	904042
43332191	43332214	3	-	26627737	GBM cells	viability after 5 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.2711665076677332	[461]	[253,343]	4	hSpCas9	negative selection	904043
43340440	43340463	3	+	26627737	GBM cells	viability after 5 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.031735555127115345	[476]	[279,242]	0	hSpCas9	negative selection	904044
43340490	43340513	3	-	26627737	GBM cells	viability after 5 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	0.3108116666339622	[229]	[157,147]	5	hSpCas9	negative selection	904045
43347951	43347974	3	+	26627737	GBM cells	viability after 5 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.16084740692253763	[873]	[548,498]	2	hSpCas9	negative selection	904046
43303286	43303309	3	-	26627737	GBM cells	viability after 13 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.7197261752682449	[303]	[312,237]	8	hSpCas9	negative selection	986357
43332191	43332214	3	-	26627737	GBM cells	viability after 13 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.32033903715770995	[461]	[296,325]	4	hSpCas9	negative selection	986358
43340440	43340463	3	+	26627737	GBM cells	viability after 13 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.464453873666583	[476]	[355,357]	6	hSpCas9	negative selection	986359
43340490	43340513	3	-	26627737	GBM cells	viability after 13 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	0.11468537276165684	[229]	[165,109]	1	hSpCas9	negative selection	986360
43347951	43347974	3	+	26627737	GBM cells	viability after 13 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.07425351934085911	[873]	[533,470]	1	hSpCas9	negative selection	986361
43303286	43303309	3	-	26627737	GBM cells	viability after 21 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	1.6235126677140668	[303]	[534,484]	9	hSpCas9	negative selection	1068672
43332191	43332214	3	-	26627737	GBM cells	viability after 21 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.6053674613861169	[461]	[396,367]	6	hSpCas9	negative selection	1068673
43340440	43340463	3	+	26627737	GBM cells	viability after 21 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.2152753090988736	[476]	[217,227]	-2	hSpCas9	negative selection	1068674
43340490	43340513	3	-	26627737	GBM cells	viability after 21 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	0.5242790484588147	[229]	[209,151]	5	hSpCas9	negative selection	1068675
43347951	43347974	3	+	26627737	GBM cells	viability after 21 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.035138670091023005	[873]	[473,497]	0	hSpCas9	negative selection	1068676
43303286	43303309	3	-	26627737	RPE1	viability after 9 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.464890250889622	[1508]	[357,321]	-3	hSpCas9	negative selection	1150987
43332191	43332214	3	-	26627737	RPE1	viability after 9 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	-0.5769227211819457	[2535]	[564,489]	-4	hSpCas9	negative selection	1150988
43340440	43340463	3	+	26627737	RPE1	viability after 9 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.804059305527359	[2721]	[398,602]	-5	hSpCas9	negative selection	1150989
43340490	43340513	3	-	26627737	RPE1	viability after 9 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.18420030905497986	[565]	[134,182]	-1	hSpCas9	negative selection	1150990
43347951	43347974	3	+	26627737	RPE1	viability after 9 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.6198685746112367	[2423]	[1263,1039]	4	hSpCas9	negative selection	1150991
43303286	43303309	3	-	26627737	RPE1	viability after 12 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.4917671662295412	[1508]	[349,222]	-3	hSpCas9	negative selection	1233302
43332191	43332214	3	-	26627737	RPE1	viability after 12 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	-0.46060985218117056	[2535]	[515,472]	-3	hSpCas9	negative selection	1233303
43340440	43340463	3	+	26627737	RPE1	viability after 12 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.5707367028037154	[2721]	[504,478]	-4	hSpCas9	negative selection	1233304
43340490	43340513	3	-	26627737	RPE1	viability after 12 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.2771675090985123	[565]	[107,143]	-2	hSpCas9	negative selection	1233305
43347951	43347974	3	+	26627737	RPE1	viability after 12 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.6234542259757516	[2423]	[1182,812]	4	hSpCas9	negative selection	1233306
43303286	43303309	3	-	26627737	RPE1	viability after 15 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.27203411183468373	[1508]	[549,163]	-2	hSpCas9	negative selection	1315617
43332191	43332214	3	-	26627737	RPE1	viability after 15 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	-1.0144093378734866	[2535]	[319,388]	-6	hSpCas9	negative selection	1315618
43340440	43340463	3	+	26627737	RPE1	viability after 15 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.41177347101573014	[2721]	[617,540]	-3	hSpCas9	negative selection	1315619
43340490	43340513	3	-	26627737	RPE1	viability after 15 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.26216453898606495	[565]	[76,187]	-2	hSpCas9	negative selection	1315620
43347951	43347974	3	+	26627737	RPE1	viability after 15 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.7753188632187515	[2423]	[1138,1206]	5	hSpCas9	negative selection	1315621
43303286	43303309	3	-	26627737	RPE1	viability after 18 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.19188343802506425	[1508]	[560,137]	-1	hSpCas9	negative selection	1397932
43332191	43332214	3	-	26627737	RPE1	viability after 18 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	-0.42864076244232074	[2535]	[565,446]	-3	hSpCas9	negative selection	1397933
43340440	43340463	3	+	26627737	RPE1	viability after 18 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.7769058531105137	[2721]	[536,312]	-5	hSpCas9	negative selection	1397934
43340490	43340513	3	-	26627737	RPE1	viability after 18 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.7789492848361773	[565]	[74,103]	-5	hSpCas9	negative selection	1397935
43347951	43347974	3	+	26627737	RPE1	viability after 18 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.8542546194753888	[2423]	[1316,1038]	5	hSpCas9	negative selection	1397936
43303286	43303309	3	-	26627737	HeLa	viability after 8 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.6294699809757212	[451]	[294,329,286]	5	hSpCas9	negative selection	1480247
43332191	43332214	3	-	26627737	HeLa	viability after 8 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.7526241688881166	[506]	[596,333,242]	6	hSpCas9	negative selection	1480248
43340440	43340463	3	+	26627737	HeLa	viability after 8 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.251707918067295	[797]	[819,336,188]	2	hSpCas9	negative selection	1480249
43340490	43340513	3	-	26627737	HeLa	viability after 8 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	1.0836757289710803	[203]	[214,280,81]	8	hSpCas9	negative selection	1480250
43347951	43347974	3	+	26627737	HeLa	viability after 8 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	-0.2747144876319245	[1724]	[645,644,578]	-3	hSpCas9	negative selection	1480251
43303286	43303309	3	-	26627737	HeLa	viability after 12 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.054167133023086955	[451]	[256,152,177]	0	hSpCas9	negative selection	1562562
43332191	43332214	3	-	26627737	HeLa	viability after 12 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.2185734382966345	[506]	[368,196,173]	2	hSpCas9	negative selection	1562563
43340440	43340463	3	+	26627737	HeLa	viability after 12 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.4444308120953868	[797]	[448,394,507]	4	hSpCas9	negative selection	1562564
43340490	43340513	3	-	26627737	HeLa	viability after 12 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	0.1938139860685627	[203]	[103,53,135]	1	hSpCas9	negative selection	1562565
43347951	43347974	3	+	26627737	HeLa	viability after 12 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	-0.8554830256923962	[1724]	[320,505,340]	-7	hSpCas9	negative selection	1562566
43303286	43303309	3	-	26627737	HeLa	viability after 15 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.230361765384537	[451]	[175,305,161]	2	hSpCas9	negative selection	1644877
43332191	43332214	3	-	26627737	HeLa	viability after 15 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.17203408326157094	[506]	[232,154,315]	1	hSpCas9	negative selection	1644878
43340440	43340463	3	+	26627737	HeLa	viability after 15 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.8452153011705357	[797]	[566,758,411]	6	hSpCas9	negative selection	1644879
43340490	43340513	3	-	26627737	HeLa	viability after 15 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.1965561201225704	[203]	[36,130,47]	-2	hSpCas9	negative selection	1644880
43347951	43347974	3	+	26627737	HeLa	viability after 15 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	-0.14614690827431254	[1724]	[720,506,677]	-1	hSpCas9	negative selection	1644881
43303286	43303309	3	-	26627737	HeLa	viability after 18 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.22212335220294815	[451]	[111,257,161]	2	hSpCas9	negative selection	1727192
43332191	43332214	3	-	26627737	HeLa	viability after 18 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.17772995449589085	[506]	[159,125,315]	1	hSpCas9	negative selection	1727193
43340440	43340463	3	+	26627737	HeLa	viability after 18 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.8525472412137787	[797]	[380,634,411]	6	hSpCas9	negative selection	1727194
43340490	43340513	3	-	26627737	HeLa	viability after 18 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.1562178572003884	[203]	[25,111,47]	-1	hSpCas9	negative selection	1727195
43347951	43347974	3	+	26627737	HeLa	viability after 18 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	-0.14709960883755402	[1724]	[477,425,677]	-1	hSpCas9	negative selection	1727196
43303286	43303309	3	-	26627737	HCT116	viability after 6 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.21669527146155043	[974]	[132,202]	1	hSpCas9	negative selection	1809507
43332191	43332214	3	-	26627737	HCT116	viability after 6 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	1.2167335720451335	[670]	[560,70]	6	hSpCas9	negative selection	1809508
43340440	43340463	3	+	26627737	HCT116	viability after 6 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.7292787183432887	[1254]	[196,75]	-4	hSpCas9	negative selection	1809509
43340490	43340513	3	-	26627737	HCT116	viability after 6 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-1.0859734848625786	[710]	[129,9]	-6	hSpCas9	negative selection	1809510
43347951	43347974	3	+	26627737	HCT116	viability after 6 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	1.518209001030325	[1815]	[916,762]	7	hSpCas9	negative selection	1809511
43303286	43303309	3	-	26627737	HCT116	viability after 8 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.12915905367665637	[429]	[199,178,269]	-1	hSpCas9	negative selection	1891822
43332191	43332214	3	-	26627737	HCT116	viability after 8 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.6797945689617189	[363]	[286,330,344]	6	hSpCas9	negative selection	1891823
43340440	43340463	3	+	26627737	HCT116	viability after 8 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.01929318070322228	[526]	[389,312,159]	0	hSpCas9	negative selection	1891824
43340490	43340513	3	-	26627737	HCT116	viability after 8 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.05542676622597863	[316]	[187,178,137]	0	hSpCas9	negative selection	1891825
43347951	43347974	3	+	26627737	HCT116	viability after 8 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.20583800181156686	[968]	[515,655,672]	2	hSpCas9	negative selection	1891826
43303286	43303309	3	-	26627737	HCT116	viability after 9 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.3798926110553497	[974]	[289,128]	-3	hSpCas9	negative selection	1974137
43332191	43332214	3	-	26627737	HCT116	viability after 9 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.2697685285277769	[670]	[296,151]	2	hSpCas9	negative selection	1974138
43340440	43340463	3	+	26627737	HCT116	viability after 9 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	1.5031650460606425	[1254]	[883,1001]	8	hSpCas9	negative selection	1974139
43340490	43340513	3	-	26627737	HCT116	viability after 9 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.767990899874356	[710]	[206,35]	-5	hSpCas9	negative selection	1974140
43347951	43347974	3	+	26627737	HCT116	viability after 9 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	1.2858514453511802	[1815]	[935,1376]	8	hSpCas9	negative selection	1974141
43303286	43303309	3	-	26627737	HCT116	viability after 12 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.14539258813276756	[429]	[118,268,233]	-1	hSpCas9	negative selection	2056452
43332191	43332214	3	-	26627737	HCT116	viability after 12 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.23901637746842724	[363]	[200,206,270]	2	hSpCas9	negative selection	2056453
43340440	43340463	3	+	26627737	HCT116	viability after 12 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.09147866262420312	[526]	[366,297,213]	1	hSpCas9	negative selection	2056454
43340490	43340513	3	-	26627737	HCT116	viability after 12 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.3574133745850875	[316]	[145,100,140]	-4	hSpCas9	negative selection	2056455
43347951	43347974	3	+	26627737	HCT116	viability after 12 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.20532851057188228	[968]	[642,691,423]	2	hSpCas9	negative selection	2056456
43303286	43303309	3	-	26627737	HCT116	viability after 15 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.29581322976946844	[429]	[122,187,281]	-3	hSpCas9	negative selection	2138767
43332191	43332214	3	-	26627737	HCT116	viability after 15 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.7874673744872636	[363]	[536,214,351]	7	hSpCas9	negative selection	2138768
43340440	43340463	3	+	26627737	HCT116	viability after 15 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.42618738886309904	[526]	[246,91,337]	-4	hSpCas9	negative selection	2138769
43340490	43340513	3	-	26627737	HCT116	viability after 15 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.1446749783366692	[316]	[273,122,110]	-1	hSpCas9	negative selection	2138770
43347951	43347974	3	+	26627737	HCT116	viability after 15 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.29464027609197196	[968]	[761,993,305]	3	hSpCas9	negative selection	2138771
43303286	43303309	3	-	26627737	HCT116	viability after 18 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.27738890735458643	[429]	[193,188,382]	2	hSpCas9	negative selection	2221082
43332191	43332214	3	-	26627737	HCT116	viability after 18 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.9380742733249932	[363]	[301,372,333]	7	hSpCas9	negative selection	2221083
43340440	43340463	3	+	26627737	HCT116	viability after 18 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.014328656189079081	[526]	[321,161,295]	0	hSpCas9	negative selection	2221084
43340490	43340513	3	-	26627737	HCT116	viability after 18 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.09621977964576874	[316]	[135,112,184]	-1	hSpCas9	negative selection	2221085
43347951	43347974	3	+	26627737	HCT116	viability after 18 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.2977492913725919	[968]	[459,884,351]	2	hSpCas9	negative selection	2221086
43303189	43303212	3	+	24336569	HL60	viability	TTCTGTTGGACCAGCATGGCAGG	SNRK	ENSG00000163788	0.5583442897604993	[670]	[2090]	5	hSpCas9	negative selection	2296249
43303201	43303224	3	+	24336569	HL60	viability	AGCATGGCAGGATTTAAGCGAGG	SNRK	ENSG00000163788	0.1032551185538515	[2349]	[5341]	1	hSpCas9	negative selection	2296250
43303210	43303233	3	+	24336569	HL60	viability	GGATTTAAGCGAGGGTATGATGG	SNRK	ENSG00000163788	1.0584661605155787	[512]	[2260]	7	hSpCas9	negative selection	2296251
43303222	43303245	3	+	24336569	HL60	viability	GGGTATGATGGAAAGATTGCTGG	SNRK	ENSG00000163788	-0.2163245182211211	[1635]	[2979]	-2	hSpCas9	negative selection	2296252
43303236	43303259	3	+	24336569	HL60	viability	GATTGCTGGATTATATGATCTGG	SNRK	ENSG00000163788	0.5835204835234651	[525]	[1667]	5	hSpCas9	negative selection	2296253
43303283	43303306	3	+	24336569	HL60	viability	TTGCCGTGGTTAAACTTGCCAGG	SNRK	ENSG00000163788	0.3414484911024738	[981]	[2632]	3	hSpCas9	negative selection	2296254
43303296	43303319	3	+	24336569	HL60	viability	ACTTGCCAGGCATGTCTTTACGG	SNRK	ENSG00000163788	0.5530185359360587	[1259]	[3911]	5	hSpCas9	negative selection	2296255
43303301	43303324	3	-	24336569	HL60	viability	TTCACCCGTAAAGACATGCCTGG	SNRK	ENSG00000163788	0.4091112740836196	[978]	[2750]	4	hSpCas9	negative selection	2296256
43303354	43303377	3	+	24336569	HL60	viability	AAACTGGACACTCTAGCTACTGG	SNRK	ENSG00000163788	1.561019160451552	[798]	[4988]	9	hSpCas9	negative selection	2296257
43303386	43303409	3	-	24336569	HL60	viability	GTTTCATGCATCTCACTTCCTGG	SNRK	ENSG00000163788	1.8911026692479915	[145]	[1145]	9	hSpCas9	negative selection	2296258
43303189	43303212	3	+	24336569	KBM7	viability	TTCTGTTGGACCAGCATGGCAGG	SNRK	ENSG00000163788	0.24336032236826466	[585]	[1891]	2	hSpCas9	negative selection	2363426
43303201	43303224	3	+	24336569	KBM7	viability	AGCATGGCAGGATTTAAGCGAGG	SNRK	ENSG00000163788	0.17631018954153355	[1620]	[4995]	1	hSpCas9	negative selection	2363427
43303210	43303233	3	+	24336569	KBM7	viability	GGATTTAAGCGAGGGTATGATGG	SNRK	ENSG00000163788	1.3606793866976086	[455]	[3193]	9	hSpCas9	negative selection	2363428
43303222	43303245	3	+	24336569	KBM7	viability	GGGTATGATGGAAAGATTGCTGG	SNRK	ENSG00000163788	1.0369114573041078	[990]	[5545]	8	hSpCas9	negative selection	2363429
43303236	43303259	3	+	24336569	KBM7	viability	GATTGCTGGATTATATGATCTGG	SNRK	ENSG00000163788	1.3377640308942749	[433]	[2991]	9	hSpCas9	negative selection	2363430
43303283	43303306	3	+	24336569	KBM7	viability	TTGCCGTGGTTAAACTTGCCAGG	SNRK	ENSG00000163788	0.8740246607731441	[889]	[4448]	7	hSpCas9	negative selection	2363431
43303296	43303319	3	+	24336569	KBM7	viability	ACTTGCCAGGCATGTCTTTACGG	SNRK	ENSG00000163788	0.4434262431146623	[1174]	[4357]	4	hSpCas9	negative selection	2363432
43303301	43303324	3	-	24336569	KBM7	viability	TTCACCCGTAAAGACATGCCTGG	SNRK	ENSG00000163788	0.5958787591348933	[980]	[4043]	5	hSpCas9	negative selection	2363433
43303354	43303377	3	+	24336569	KBM7	viability	AAACTGGACACTCTAGCTACTGG	SNRK	ENSG00000163788	0.6365369491259506	[786]	[3336]	6	hSpCas9	negative selection	2363434
43303386	43303409	3	-	24336569	KBM7	viability	GTTTCATGCATCTCACTTCCTGG	SNRK	ENSG00000163788	0.7414100665203518	[283]	[1294]	6	hSpCas9	negative selection	2363435
43309654	43309677	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TAGCCCAGGCTGGAGTGTAGTGG	SNRK	ENSG00000163788	1.7114406221969245	[69,25]	[57,8]	6	dCas9-VP64	positive selection	2392332
43333181	43333204	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGACGGGGTTTCACCATGTAAG	SNRK	ENSG00000163788	1.7100356304154607	[4,2]	[3,0]	6	dCas9-VP64	positive selection	2409623
43333885	43333908	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCCCAGCACTTAAG	SNRK	ENSG00000163788	-0.7697329427055237	[305,492]	[31,71]	-4	dCas9-VP64	positive selection	2453102
43322825	43322848	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAGTCCCAGCTACTCAGG	SNRK	ENSG00000163788	0.4848717924049799	[259,492]	[140,88]	2	dCas9-VP64	positive selection	2468749
43309654	43309677	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TAGCCCAGGCTGGAGTGTAGTGG	SNRK	ENSG00000163788	1.81784862797452	[47,48]	[40,70]	8	dCas9-VP64	positive selection	2487587
43333181	43333204	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGACGGGGTTTCACCATGTAAG	SNRK	ENSG00000163788	-0.28524240662887035	[88,68]	[26,14]	-3	dCas9-VP64	positive selection	2504878
43333885	43333908	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCCCAGCACTTAAG	SNRK	ENSG00000163788	-0.7960951384238878	[400,199]	[64,47]	-7	dCas9-VP64	positive selection	2548357
43322825	43322848	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAGTCCCAGCTACTCAGG	SNRK	ENSG00000163788	0.2857588864060996	[349,998]	[76,442]	2	dCas9-VP64	positive selection	2564004
43303354	43303377	3	+	27260157	DLD1	viability	AAACTGGACACTCTAGCTACTGG	SNRK	ENSG00000163788	0.706404782518216	[]	[]	8	hSpCas9	negative selection	2579791
43303222	43303245	3	+	27260157	DLD1	viability	GGGTATGATGGAAAGATTGCTGG	SNRK	ENSG00000163788	-0.598509088314032	[]	[]	-5	hSpCas9	negative selection	2581415
43303189	43303212	3	+	27260157	DLD1	viability	TTCTGTTGGACCAGCATGGCAGG	SNRK	ENSG00000163788	0.608337955699573	[]	[]	8	hSpCas9	negative selection	2584284
43340440	43340463	3	+	27260157	DLD1	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	1.2880347635193	[]	[]	9	hSpCas9	negative selection	2604253
43303386	43303409	3	-	27260157	DLD1	viability	GTTTCATGCATCTCACTTCCTGG	SNRK	ENSG00000163788	-0.899568776239138	[]	[]	-6	hSpCas9	negative selection	2605708
43303236	43303259	3	+	27260157	DLD1	viability	GATTGCTGGATTATATGATCTGG	SNRK	ENSG00000163788	0.337527184799282	[]	[]	4	hSpCas9	negative selection	2610115
43303296	43303319	3	+	27260157	DLD1	viability	ACTTGCCAGGCATGTCTTTACGG	SNRK	ENSG00000163788	0.376882888193013	[]	[]	4	hSpCas9	negative selection	2612264
43303210	43303233	3	+	27260157	DLD1	viability	GGATTTAAGCGAGGGTATGATGG	SNRK	ENSG00000163788	-0.100979036912113	[]	[]	0	hSpCas9	negative selection	2613210
43340490	43340513	3	-	27260157	DLD1	viability	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	0.298018757871649	[]	[]	4	hSpCas9	negative selection	2613523
43303283	43303306	3	+	27260157	DLD1	viability	TTGCCGTGGTTAAACTTGCCAGG	SNRK	ENSG00000163788	-0.204364012965825	[]	[]	-1	hSpCas9	negative selection	2614348
43303286	43303309	3	-	27260157	DLD1	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.898507811517959	[]	[]	9	hSpCas9	negative selection	2617762
43303708	43303731	3	+	27260157	DLD1	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.444352344413743	[]	[]	7	hSpCas9	negative selection	2620904
43332216	43332239	3	-	27260157	DLD1	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.415766301709063	[]	[]	4	hSpCas9	negative selection	2640801
43303301	43303324	3	-	27260157	DLD1	viability	TTCACCCGTAAAGACATGCCTGG	SNRK	ENSG00000163788	0.0277881954031738	[]	[]	0	hSpCas9	negative selection	2642719
43303201	43303224	3	+	27260157	DLD1	viability	AGCATGGCAGGATTTAAGCGAGG	SNRK	ENSG00000163788	0.200081558018238	[]	[]	3	hSpCas9	negative selection	2644324
43343439	43343462	3	-	27260157	DLD1	viability	ATTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	0.167825535525264	[]	[]	3	hSpCas9	negative selection	2645056
43303354	43303377	3	+	27260157	HT1080	viability	AAACTGGACACTCTAGCTACTGG	SNRK	ENSG00000163788	0.0232595970292424	[]	[]	0	hSpCas9	negative selection	2655921
43303222	43303245	3	+	27260157	HT1080	viability	GGGTATGATGGAAAGATTGCTGG	SNRK	ENSG00000163788	-0.19831901065057	[]	[]	0	hSpCas9	negative selection	2657545
43303189	43303212	3	+	27260157	HT1080	viability	TTCTGTTGGACCAGCATGGCAGG	SNRK	ENSG00000163788	1.56883907549831	[]	[]	9	hSpCas9	negative selection	2660414
43340440	43340463	3	+	27260157	HT1080	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	1.518641149042	[]	[]	9	hSpCas9	negative selection	2680383
43303386	43303409	3	-	27260157	HT1080	viability	GTTTCATGCATCTCACTTCCTGG	SNRK	ENSG00000163788	0.414118297829246	[]	[]	4	hSpCas9	negative selection	2681838
43303236	43303259	3	+	27260157	HT1080	viability	GATTGCTGGATTATATGATCTGG	SNRK	ENSG00000163788	-0.157928424035361	[]	[]	0	hSpCas9	negative selection	2686245
43303296	43303319	3	+	27260157	HT1080	viability	ACTTGCCAGGCATGTCTTTACGG	SNRK	ENSG00000163788	0.165260171937796	[]	[]	1	hSpCas9	negative selection	2688394
43303210	43303233	3	+	27260157	HT1080	viability	GGATTTAAGCGAGGGTATGATGG	SNRK	ENSG00000163788	-0.519327331862482	[]	[]	-7	hSpCas9	negative selection	2689340
43340490	43340513	3	-	27260157	HT1080	viability	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	0.254849501020053	[]	[]	2	hSpCas9	negative selection	2689653
43303283	43303306	3	+	27260157	HT1080	viability	TTGCCGTGGTTAAACTTGCCAGG	SNRK	ENSG00000163788	-0.593289591075124	[]	[]	-7	hSpCas9	negative selection	2690478
43303286	43303309	3	-	27260157	HT1080	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.0130646818925523	[]	[]	0	hSpCas9	negative selection	2693892
43303708	43303731	3	+	27260157	HT1080	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.971804721912885	[]	[]	7	hSpCas9	negative selection	2697034
43332216	43332239	3	-	27260157	HT1080	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.328429622948191	[]	[]	3	hSpCas9	negative selection	2716931
43303301	43303324	3	-	27260157	HT1080	viability	TTCACCCGTAAAGACATGCCTGG	SNRK	ENSG00000163788	0.490805397486188	[]	[]	4	hSpCas9	negative selection	2718849
43303201	43303224	3	+	27260157	HT1080	viability	AGCATGGCAGGATTTAAGCGAGG	SNRK	ENSG00000163788	0.0789402303262891	[]	[]	0	hSpCas9	negative selection	2720454
43343439	43343462	3	-	27260157	HT1080	viability	ATTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	0.941878458775455	[]	[]	7	hSpCas9	negative selection	2721186
43303354	43303377	3	+	27260157	MKN45	viability	AAACTGGACACTCTAGCTACTGG	SNRK	ENSG00000163788	0.096299619490468	[]	[]	0	hSpCas9	negative selection	2732051
43303222	43303245	3	+	27260157	MKN45	viability	GGGTATGATGGAAAGATTGCTGG	SNRK	ENSG00000163788	-0.923254535823006	[]	[]	-7	hSpCas9	negative selection	2733675
43303189	43303212	3	+	27260157	MKN45	viability	TTCTGTTGGACCAGCATGGCAGG	SNRK	ENSG00000163788	1.30728712435462	[]	[]	9	hSpCas9	negative selection	2736544
43340440	43340463	3	+	27260157	MKN45	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	1.80877391718936	[]	[]	9	hSpCas9	negative selection	2756513
43303386	43303409	3	-	27260157	MKN45	viability	GTTTCATGCATCTCACTTCCTGG	SNRK	ENSG00000163788	0.702199953113028	[]	[]	7	hSpCas9	negative selection	2757968
43303236	43303259	3	+	27260157	MKN45	viability	GATTGCTGGATTATATGATCTGG	SNRK	ENSG00000163788	0.0015990103360282	[]	[]	0	hSpCas9	negative selection	2762375
43303296	43303319	3	+	27260157	MKN45	viability	ACTTGCCAGGCATGTCTTTACGG	SNRK	ENSG00000163788	-0.524149457715673	[]	[]	-6	hSpCas9	negative selection	2764524
43303210	43303233	3	+	27260157	MKN45	viability	GGATTTAAGCGAGGGTATGATGG	SNRK	ENSG00000163788	0.539605637310428	[]	[]	7	hSpCas9	negative selection	2765470
43340490	43340513	3	-	27260157	MKN45	viability	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.191581446250869	[]	[]	0	hSpCas9	negative selection	2765783
43303283	43303306	3	+	27260157	MKN45	viability	TTGCCGTGGTTAAACTTGCCAGG	SNRK	ENSG00000163788	-1.04967344490874	[]	[]	-8	hSpCas9	negative selection	2766608
43303286	43303309	3	-	27260157	MKN45	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.0873856187474488	[]	[]	0	hSpCas9	negative selection	2770022
43303708	43303731	3	+	27260157	MKN45	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	1.17881971802306	[]	[]	8	hSpCas9	negative selection	2773164
43332216	43332239	3	-	27260157	MKN45	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	-0.0227042095977903	[]	[]	0	hSpCas9	negative selection	2793061
43303301	43303324	3	-	27260157	MKN45	viability	TTCACCCGTAAAGACATGCCTGG	SNRK	ENSG00000163788	0.741267442774876	[]	[]	7	hSpCas9	negative selection	2794979
43303201	43303224	3	+	27260157	MKN45	viability	AGCATGGCAGGATTTAAGCGAGG	SNRK	ENSG00000163788	0.420333826005189	[]	[]	6	hSpCas9	negative selection	2796584
43343439	43343462	3	-	27260157	MKN45	viability	ATTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	0.478441989405236	[]	[]	6	hSpCas9	negative selection	2797316
43303354	43303377	3	+	27260157	RKO	viability	AAACTGGACACTCTAGCTACTGG	SNRK	ENSG00000163788	0.47771558004199	[]	[]	2	hSpCas9	negative selection	2808181
43303222	43303245	3	+	27260157	RKO	viability	GGGTATGATGGAAAGATTGCTGG	SNRK	ENSG00000163788	-0.734590344154828	[]	[]	-7	hSpCas9	negative selection	2809805
43303189	43303212	3	+	27260157	RKO	viability	TTCTGTTGGACCAGCATGGCAGG	SNRK	ENSG00000163788	0.868103505293654	[]	[]	8	hSpCas9	negative selection	2812674
43340440	43340463	3	+	27260157	RKO	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.961536158486767	[]	[]	8	hSpCas9	negative selection	2832643
43303386	43303409	3	-	27260157	RKO	viability	GTTTCATGCATCTCACTTCCTGG	SNRK	ENSG00000163788	0.0408356114924275	[]	[]	0	hSpCas9	negative selection	2834098
43303236	43303259	3	+	27260157	RKO	viability	GATTGCTGGATTATATGATCTGG	SNRK	ENSG00000163788	-0.2195277210417	[]	[]	-1	hSpCas9	negative selection	2838505
43303296	43303319	3	+	27260157	RKO	viability	ACTTGCCAGGCATGTCTTTACGG	SNRK	ENSG00000163788	-0.0997805688474493	[]	[]	0	hSpCas9	negative selection	2840654
43303210	43303233	3	+	27260157	RKO	viability	GGATTTAAGCGAGGGTATGATGG	SNRK	ENSG00000163788	-0.104906118293401	[]	[]	0	hSpCas9	negative selection	2841600
43340490	43340513	3	-	27260157	RKO	viability	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.546581792048508	[]	[]	-7	hSpCas9	negative selection	2841913
43303283	43303306	3	+	27260157	RKO	viability	TTGCCGTGGTTAAACTTGCCAGG	SNRK	ENSG00000163788	-0.704638561505645	[]	[]	-7	hSpCas9	negative selection	2842738
43303286	43303309	3	-	27260157	RKO	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.283304121484635	[]	[]	1	hSpCas9	negative selection	2846152
43303708	43303731	3	+	27260157	RKO	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.59460472119378	[]	[]	3	hSpCas9	negative selection	2849294
43332216	43332239	3	-	27260157	RKO	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	-0.527431183189157	[]	[]	-6	hSpCas9	negative selection	2869191
43303301	43303324	3	-	27260157	RKO	viability	TTCACCCGTAAAGACATGCCTGG	SNRK	ENSG00000163788	0.723643270640096	[]	[]	8	hSpCas9	negative selection	2871109
43303201	43303224	3	+	27260157	RKO	viability	AGCATGGCAGGATTTAAGCGAGG	SNRK	ENSG00000163788	0.0407095573724269	[]	[]	0	hSpCas9	negative selection	2872714
43343439	43343462	3	-	27260157	RKO	viability	ATTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	0.6903523585833	[]	[]	7	hSpCas9	negative selection	2873446
43303354	43303377	3	+	27260157	SF268	viability	AAACTGGACACTCTAGCTACTGG	SNRK	ENSG00000163788	0.125152998020132	[]	[]	0	hSpCas9	negative selection	2884311
43303222	43303245	3	+	27260157	SF268	viability	GGGTATGATGGAAAGATTGCTGG	SNRK	ENSG00000163788	-0.277147687596947	[]	[]	-2	hSpCas9	negative selection	2885935
43303189	43303212	3	+	27260157	SF268	viability	TTCTGTTGGACCAGCATGGCAGG	SNRK	ENSG00000163788	0.886427985222674	[]	[]	9	hSpCas9	negative selection	2888804
43340440	43340463	3	+	27260157	SF268	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	1.01333679044331	[]	[]	9	hSpCas9	negative selection	2908773
43303386	43303409	3	-	27260157	SF268	viability	GTTTCATGCATCTCACTTCCTGG	SNRK	ENSG00000163788	0.54388393723248	[]	[]	8	hSpCas9	negative selection	2910228
43303236	43303259	3	+	27260157	SF268	viability	GATTGCTGGATTATATGATCTGG	SNRK	ENSG00000163788	-0.442793201951387	[]	[]	-3	hSpCas9	negative selection	2914635
43303296	43303319	3	+	27260157	SF268	viability	ACTTGCCAGGCATGTCTTTACGG	SNRK	ENSG00000163788	-0.00629172891961224	[]	[]	0	hSpCas9	negative selection	2916784
43303210	43303233	3	+	27260157	SF268	viability	GGATTTAAGCGAGGGTATGATGG	SNRK	ENSG00000163788	-0.372803422451157	[]	[]	-3	hSpCas9	negative selection	2917730
43340490	43340513	3	-	27260157	SF268	viability	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.786985920151203	[]	[]	-6	hSpCas9	negative selection	2918043
43303283	43303306	3	+	27260157	SF268	viability	TTGCCGTGGTTAAACTTGCCAGG	SNRK	ENSG00000163788	-1.34828159847122	[]	[]	-7	hSpCas9	negative selection	2918868
43303286	43303309	3	-	27260157	SF268	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.420800348836694	[]	[]	-3	hSpCas9	negative selection	2922282
43303708	43303731	3	+	27260157	SF268	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.507115454845502	[]	[]	7	hSpCas9	negative selection	2925424
43332216	43332239	3	-	27260157	SF268	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	-0.0907671997068533	[]	[]	0	hSpCas9	negative selection	2945321
43303301	43303324	3	-	27260157	SF268	viability	TTCACCCGTAAAGACATGCCTGG	SNRK	ENSG00000163788	-0.184461765837809	[]	[]	-1	hSpCas9	negative selection	2947239
43303201	43303224	3	+	27260157	SF268	viability	AGCATGGCAGGATTTAAGCGAGG	SNRK	ENSG00000163788	-0.383342382546895	[]	[]	-3	hSpCas9	negative selection	2948844
43343439	43343462	3	-	27260157	SF268	viability	ATTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	-0.176195007157115	[]	[]	-1	hSpCas9	negative selection	2949576
43303185	43303208	3	+	27013184	SW480	treatment with recombinant TRAIL	TTTCTTCTGTTGGACCAGCATGG	SNRK	ENSG00000163788	-1.2398760802749562	[213,93]	[5,61]	-5	hSpCas9	positive selection	2963200
43332182	43332205	3	+	27013184	SW480	treatment with recombinant TRAIL	GGGAGTGATCCTTTTCATGTTGG	SNRK	ENSG00000163788	-0.0650902013678053	[342,389]	[87,238]	0	hSpCas9	positive selection	2963201
43303189	43303212	3	+	27013184	SW480	treatment with recombinant TRAIL	TTCTGTTGGACCAGCATGGCAGG	SNRK	ENSG00000163788	0.5012497637939161	[156,236]	[73,180]	2	hSpCas9	positive selection	2963202
43332242	43332265	3	+	27013184	SW480	treatment with recombinant TRAIL	TGAAACACTGACAATGATCATGG	SNRK	ENSG00000163788	-0.01809588403588691	[101,56]	[23,49]	0	hSpCas9	positive selection	2963203
43343453	43343476	3	-	27013184	SW480	treatment with recombinant TRAIL	AACTGGGCCTTGATATTGCTCGG	SNRK	ENSG00000163788	-0.056163327599723645	[304,595]	[193,163]	0	hSpCas9	positive selection	2963204
43343374	43343397	3	+	27013184	SW480	treatment with recombinant TRAIL	CACAGCCACATACTTCCTGCTGG	SNRK	ENSG00000163788	0.30605451793331007	[14,39]	[4,26]	1	hSpCas9	positive selection	2963208
43343382	43343405	3	+	27013184	SW480	treatment with recombinant TRAIL	CATACTTCCTGCTGGCTGAAAGG	SNRK	ENSG00000163788	0.05486973324829514	[183,132]	[17,148]	0	hSpCas9	positive selection	2963209
43343446	43343469	3	+	27013184	SW480	treatment with recombinant TRAIL	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.5224661172214868	[17,103]	[20,55]	2	hSpCas9	positive selection	2963210
43343457	43343480	3	+	27013184	SW480	treatment with recombinant TRAIL	GCAATATCAAGGCCCAGTTTAGG	SNRK	ENSG00000163788	-0.002946441288999291	[263,292]	[132,99]	0	hSpCas9	positive selection	2963211
43303201	43303224	3	+	27013184	SW480	treatment with recombinant TRAIL	AGCATGGCAGGATTTAAGCGAGG	SNRK	ENSG00000163788	3.0810357898307648	[4,38]	[125,1]	9	hSpCas9	positive selection	2963212
43303199	43303222	3	-	27013184	SW480	treatment with recombinant TRAIL	TCGCTTAAATCCTGCCATGCTGG	SNRK	ENSG00000163788	-0.7808968736683386	[260,386]	[41,133]	-4	hSpCas9	positive selection	2963213
43303202	43303225	3	+	27013184	SW480	treatment with recombinant TRAIL	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	-0.0018458771034576271	[97,173]	[38,82]	0	hSpCas9	positive selection	2963214
43303248	43303271	3	+	27013184	SW480	treatment with recombinant TRAIL	ATATGATCTGGATAAAACCTTGG	SNRK	ENSG00000163788	-3.010296534627943	[18,109]	[1,4]	-8	hSpCas9	positive selection	2963215
43303249	43303272	3	+	27013184	SW480	treatment with recombinant TRAIL	TATGATCTGGATAAAACCTTGGG	SNRK	ENSG00000163788	-0.7854314806596419	[132,117]	[5,67]	-4	hSpCas9	positive selection	2963216
43303255	43303278	3	+	27013184	SW480	treatment with recombinant TRAIL	CTGGATAAAACCTTGGGTCGAGG	SNRK	ENSG00000163788	-1.5870554133430361	[85,67]	[11,9]	-6	hSpCas9	positive selection	2963217
43332216	43332239	3	-	27013184	SW480	treatment with recombinant TRAIL	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.7310690337832499	[217,93]	[99,137]	3	hSpCas9	positive selection	2963218
43332220	43332243	3	-	27013184	SW480	treatment with recombinant TRAIL	ACTGTCATTGGCTTCTTGAAAGG	SNRK	ENSG00000163788	-0.21450793363164067	[685,750]	[176,392]	-1	hSpCas9	positive selection	2963219
43332232	43332255	3	-	27013184	SW480	treatment with recombinant TRAIL	TGTCAGTGTTTCACTGTCATTGG	SNRK	ENSG00000163788	0.7722041819315805	[261,197]	[138,217]	4	hSpCas9	positive selection	2963220
43332282	43332305	3	-	27013184	SW480	treatment with recombinant TRAIL	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	0.020633027103713175	[84,144]	[23,84]	0	hSpCas9	positive selection	2963221
43332286	43332309	3	-	27013184	SW480	treatment with recombinant TRAIL	TTTACACTCTTTAGACACATGGG	SNRK	ENSG00000163788	1.83391509527628	[95,201]	[228,211]	7	hSpCas9	positive selection	2963222
43332287	43332310	3	-	27013184	SW480	treatment with recombinant TRAIL	CTTTACACTCTTTAGACACATGG	SNRK	ENSG00000163788	0.035167453616422456	[190,228]	[94,87]	0	hSpCas9	positive selection	2963223
43343346	43343369	3	-	27013184	SW480	treatment with recombinant TRAIL	GTTATACCTGTTGGTTTCCAGGG	SNRK	ENSG00000163788	-0.208061792224429	[123,81]	[13,74]	-1	hSpCas9	positive selection	2963224
43343347	43343370	3	-	27013184	SW480	treatment with recombinant TRAIL	GGTTATACCTGTTGGTTTCCAGG	SNRK	ENSG00000163788	1.606210485489841	[172,279]	[403,130]	7	hSpCas9	positive selection	2963225
43343379	43343402	3	-	27013184	SW480	treatment with recombinant TRAIL	TTCAGCCAGCAGGAAGTATGTGG	SNRK	ENSG00000163788	-1.0410682823226802	[167,397]	[95,1]	-5	hSpCas9	positive selection	2963226
43343389	43343412	3	-	27013184	SW480	treatment with recombinant TRAIL	TCAGGATCCTTTCAGCCAGCAGG	SNRK	ENSG00000163788	1.151520645764283	[301,307]	[365,186]	5	hSpCas9	positive selection	2963227
43343439	43343462	3	-	27013184	SW480	treatment with recombinant TRAIL	ATTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	0.34601542616730274	[944,1129]	[604,506]	1	hSpCas9	positive selection	2963228
43343452	43343475	3	-	27013184	SW480	treatment with recombinant TRAIL	ACTGGGCCTTGATATTGCTCGGG	SNRK	ENSG00000163788	0.7436966272433437	[417,426]	[252,378]	3	hSpCas9	positive selection	2963229
43303203	43303226	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	0.0019500290039476953	[2,2]	[1,2]	0	hSpCas9	positive selection	3022436
43343341	43343364	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGAGCCCTGGAAACCAACAGG	SNRK	ENSG00000163788	-0.03361828599756109	[2,3]	[5,0]	0	hSpCas9	positive selection	3022437
43303686	43303709	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	0.15295957588017647	[3,3]	[3,3]	3	hSpCas9	positive selection	3022438
43303588	43303611	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATTGCCATAAACTCCATGTGG	SNRK	ENSG00000163788	0.2402845789459542	[3,3]	[2,4]	5	hSpCas9	positive selection	3022439
43303203	43303226	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	0.480828033151166	[2,2]	[0,3]	7	hSpCas9	positive selection	3090294
43343341	43343364	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGAGCCCTGGAAACCAACAGG	SNRK	ENSG00000163788	-0.4644816735214279	[2,2]	[2,0]	-6	hSpCas9	positive selection	3090295
43303686	43303709	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	-0.19838961796116586	[3,3]	[3,0]	-3	hSpCas9	positive selection	3090296
43303588	43303611	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATTGCCATAAACTCCATGTGG	SNRK	ENSG00000163788	0.009186041101884087	[3,3]	[2,2]	0	hSpCas9	positive selection	3090297
43340440	43340463		+	24336571	A375	resistance to PLX after 7 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.13026547071019756	[23,24]	[21,22]	-4	hSpCas9	positive selection	3146392
43332287	43332310		-	24336571	A375	resistance to PLX after 7 days	CTTTACACTCTTTAGACACATGG	SNRK	ENSG00000163788	0.10267254857608554	[8,9]	[9,9]	3	hSpCas9	positive selection	3146393
43332232	43332255		-	24336571	A375	resistance to PLX after 7 days	TGTCAGTGTTTCACTGTCATTGG	SNRK	ENSG00000163788	0.08589436437685749	[25,24]	[27,25]	3	hSpCas9	positive selection	3146394
43340440	43340463		+	24336571	A375	resistance to PLX after 14 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.4096698681906139	[18,28]	[13,15]	4	hSpCas9	positive selection	3204185
43332287	43332310		-	24336571	A375	resistance to PLX after 14 days	CTTTACACTCTTTAGACACATGG	SNRK	ENSG00000163788	0.3810637303566867	[11,6]	[5,5]	3	hSpCas9	positive selection	3204186
43332232	43332255		-	24336571	A375	resistance to PLX after 14 days	TGTCAGTGTTTCACTGTCATTGG	SNRK	ENSG00000163788	-0.35077791583008455	[29,37]	[11,11]	-4	hSpCas9	positive selection	3204187
43340440	43340463		+	24336571	A375	viability after 7 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.4766705081034273	[17]	[23,24]	7	hSpCas9	negative selection	3261978
43332287	43332310		-	24336571	A375	viability after 7 days	CTTTACACTCTTTAGACACATGG	SNRK	ENSG00000163788	-0.6814533193620991	[15]	[8,9]	-7	hSpCas9	negative selection	3261979
43332232	43332255		-	24336571	A375	viability after 7 days	TGTCAGTGTTTCACTGTCATTGG	SNRK	ENSG00000163788	0.8123397228457236	[14]	[25,24]	9	hSpCas9	negative selection	3261980
43340440	43340463		+	24336571	A375	viability after 14 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.4971080322566363	[17]	[18,28]	6	hSpCas9	negative selection	3319771
43332287	43332310		-	24336571	A375	viability after 14 days	CTTTACACTCTTTAGACACATGG	SNRK	ENSG00000163788	-0.6351744662218822	[15]	[11,6]	-6	hSpCas9	negative selection	3319772
43332232	43332255		-	24336571	A375	viability after 14 days	TGTCAGTGTTTCACTGTCATTGG	SNRK	ENSG00000163788	1.230482231650093	[14]	[29,37]	9	hSpCas9	negative selection	3319773
43343355	43343378	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-1.2305138223772163	[358,358]	[0,0]	-7	hSpCas9	positive selection	3394071
43340440	43340463	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.009460329249066228	[153,153]	[0,0]	0	hSpCas9	positive selection	3394072
43340381	43340404	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.41183616050145994	[114,114]	[0,0]	2	hSpCas9	positive selection	3394073
43303202	43303225	3	+	26780180	HT29	viability (Avana library 4 designs)	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	2.00661331066698	[]	[]	7	hSpCas9	negative selection	3461032
43343340	43343363	3	+	26780180	HT29	viability (Avana library 4 designs)	TCAGAGCCCTGGAAACCAACAGG	SNRK	ENSG00000163788	0.95079714838776	[]	[]	3	hSpCas9	negative selection	3461033
43303685	43303708	3	+	26780180	HT29	viability (Avana library 4 designs)	TCAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	1.85372350213726	[]	[]	7	hSpCas9	negative selection	3461034
43303587	43303610	3	+	26780180	HT29	viability (Avana library 4 designs)	TTATTGCCATAAACTCCATGTGG	SNRK	ENSG00000163788	1.2540815322557	[]	[]	5	hSpCas9	negative selection	3461035
43303202	43303225	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	3.42933602082046	[]	[]	5	hSpCas9	negative selection	3561684
43303587	43303610	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATTGCCATAAACTCCATGTGG	SNRK	ENSG00000163788	-5.1778216488624	[]	[]	-5	hSpCas9	negative selection	3561685
43343340	43343363	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGAGCCCTGGAAACCAACAGG	SNRK	ENSG00000163788	-4.89318167345749	[]	[]	-5	hSpCas9	negative selection	3561686
43303685	43303708	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	-13.5207697944567	[]	[]	-8	hSpCas9	negative selection	3561687
43303602	43303625	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAAGTCTCTGTGAACCACATGG	SNRK	ENSG00000163788	-0.407093313047964	[]	[]	0	hSpCas9	negative selection	3561688
43303286	43303309	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	1.30739869364546	[]	[]	1	hSpCas9	negative selection	3561689
43303202	43303225	3	+	26780180	A375	viability (Avana lentiGuide)	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	6.34054430336198	[]	[]	5	hSpCas9	negative selection	3670343
43303587	43303610	3	+	26780180	A375	viability (Avana lentiGuide)	TTATTGCCATAAACTCCATGTGG	SNRK	ENSG00000163788	-1.09956481286505	[]	[]	-2	hSpCas9	negative selection	3670344
43343340	43343363	3	+	26780180	A375	viability (Avana lentiGuide)	TCAGAGCCCTGGAAACCAACAGG	SNRK	ENSG00000163788	-7.74874366803057	[]	[]	-9	hSpCas9	negative selection	3670345
43303685	43303708	3	+	26780180	A375	viability (Avana lentiGuide)	TCAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	-0.260263774071584	[]	[]	0	hSpCas9	negative selection	3670346
43303602	43303625	3	-	26780180	A375	viability (Avana lentiGuide)	TTAAGTCTCTGTGAACCACATGG	SNRK	ENSG00000163788	-2.40404014462549	[]	[]	-4	hSpCas9	negative selection	3670347
43303286	43303309	3	-	26780180	A375	viability (Avana lentiGuide)	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	2.59479465481538	[]	[]	2	hSpCas9	negative selection	3670348
43303202	43303225	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	-0.18046536001334507	[4]	[4,2]	-3	hSpCas9	positive selection	3778950
43303587	43303610	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATTGCCATAAACTCCATGTGG	SNRK	ENSG00000163788	-0.38292826370619315	[6]	[4,4]	-5	hSpCas9	positive selection	3778951
43343340	43343363	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGAGCCCTGGAAACCAACAGG	SNRK	ENSG00000163788	-0.5139826344822044	[3]	[2,2]	-6	hSpCas9	positive selection	3778952
43303685	43303708	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	-0.40859728731717815	[5]	[3,3]	-6	hSpCas9	positive selection	3778953
43303602	43303625	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAAGTCTCTGTGAACCACATGG	SNRK	ENSG00000163788	-0.21730568887590174	[5]	[4,4]	-3	hSpCas9	positive selection	3778954
43303286	43303309	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.021706822487018697	[5]	[4,4]	0	hSpCas9	positive selection	3778955
43303202	43303225	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	-0.6404517179690812	[4]	[2,2]	-7	hSpCas9	positive selection	3887557
43303587	43303610	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATTGCCATAAACTCCATGTGG	SNRK	ENSG00000163788	-0.8903229505702414	[5]	[3,0]	-8	hSpCas9	positive selection	3887558
43343340	43343363	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGAGCCCTGGAAACCAACAGG	SNRK	ENSG00000163788	-0.26361073806468127	[3]	[2,1]	-4	hSpCas9	positive selection	3887559
43303685	43303708	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	0.22692245746315143	[5]	[4,5]	6	hSpCas9	positive selection	3887560
43303602	43303625	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAAGTCTCTGTGAACCACATGG	SNRK	ENSG00000163788	0.2502637015633609	[5]	[5,5]	6	hSpCas9	positive selection	3887561
43303286	43303309	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.07753783557322866	[5]	[3,4]	1	hSpCas9	positive selection	3887562
43340440	43340463	3	+	26780180	A375	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	1.23348021210367	[]	[]	6	hSpCas9	negative selection	3997660
43348109	43348132	3	-	26780180	A375	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	1.69267379255992	[]	[]	9	hSpCas9	negative selection	3997661
43340381	43340404	3	-	26780180	A375	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.956699472755738	[]	[]	4	hSpCas9	negative selection	3997662
43347909	43347932	3	-	26780180	A375	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	0.773214311271766	[]	[]	3	hSpCas9	negative selection	3997663
43343446	43343469	3	+	26780180	A375	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.625026444926496	[]	[]	2	hSpCas9	negative selection	3997664
43343355	43343378	3	-	26780180	A375	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	1.80529818099392	[]	[]	9	hSpCas9	negative selection	3997665
43340440	43340463	3	+	26780180	HT29	viability (GeCKOv2 library)	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	1.21222615890466	[]	[]	6	hSpCas9	negative selection	4105626
43348109	43348132	3	-	26780180	HT29	viability (GeCKOv2 library)	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	1.2254138667633	[]	[]	6	hSpCas9	negative selection	4105627
43340381	43340404	3	-	26780180	HT29	viability (GeCKOv2 library)	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	1.41898425025842	[]	[]	7	hSpCas9	negative selection	4105628
43347909	43347932	3	-	26780180	HT29	viability (GeCKOv2 library)	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	1.72097954599412	[]	[]	8	hSpCas9	negative selection	4105629
43343446	43343469	3	+	26780180	HT29	viability (GeCKOv2 library)	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.135027729792535	[]	[]	0	hSpCas9	negative selection	4105630
43343355	43343378	3	-	26780180	HT29	viability (GeCKOv2 library)	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	1.02265301764053	[]	[]	4	hSpCas9	negative selection	4105631
43340440	43340463	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.115626480956278	[4]	[2,3]	3	hSpCas9	positive selection	4172491
43332287	43332310	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTTACACTCTTTAGACACATGG	SNRK	ENSG00000163788	-0.198675378410116	[3]	[1,2]	-5	hSpCas9	positive selection	4172492
43332232	43332255	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTCAGTGTTTCACTGTCATTGG	SNRK	ENSG00000163788	0.205137227965369	[4]	[2,3]	5	hSpCas9	positive selection	4172493
43340440	43340463	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.025623031736101087	[4]	[1,4,1,0]	0	hSpCas9	positive selection	4236513
43332287	43332310	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTTACACTCTTTAGACACATGG	SNRK	ENSG00000163788	-0.14876397322917723	[4]	[4,2,0,0]	-2	hSpCas9	positive selection	4236514
43332232	43332255	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTCAGTGTTTCACTGTCATTGG	SNRK	ENSG00000163788	1.0160858605424816	[4]	[3,3,3,3]	7	hSpCas9	positive selection	4236515
43348109	43348132	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.02658326526036915	[2]	[3,1]	0	hSpCas9	positive selection	4299567
43347909	43347932	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.3840552484870817	[2]	[1,0]	-7	hSpCas9	positive selection	4299568
43343446	43343469	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.20539538260400864	[2]	[3,1]	4	hSpCas9	positive selection	4299569
43343355	43343378	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.13835574013962515	[4]	[3,2]	-3	hSpCas9	positive selection	4363819
43340440	43340463	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.07432215681308735	[2]	[2,0]	-1	hSpCas9	positive selection	4363820
43340381	43340404	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.4582255341936572	[1]	[1,0]	-7	hSpCas9	positive selection	4363821
43303306	43303328	3	+	27760321	OCIAML3	viability	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	-0.682863554401996	[275,249]	[91,174]	-6	hSpCas9	negative selection	4441740
43303686	43303708	3	+	27760321	OCIAML3	viability	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	0.23883252174047342	[207,154]	[195,126]	3	hSpCas9	negative selection	4441741
43303709	43303731	3	+	27760321	OCIAML3	viability	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.07133383212204591	[663,577]	[469,559]	0	hSpCas9	negative selection	4441742
43340381	43340403	3	-	27760321	OCIAML3	viability	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.7048626676713732	[58,40]	[39,92]	8	hSpCas9	negative selection	4441743
43343439	43343461	3	-	27760321	OCIAML3	viability	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	-0.19146640488842903	[726,776]	[462,589]	-2	hSpCas9	negative selection	4441744
43303306	43303328	3	+	27760321	OCIAML2	viability	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	0.5961403020044417	[275,249]	[225,446]	7	hSpCas9	negative selection	4525203
43303686	43303708	3	+	27760321	OCIAML2	viability	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	0.2509942258374407	[207,154]	[142,212]	3	hSpCas9	negative selection	4525204
43303709	43303731	3	+	27760321	OCIAML2	viability	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.7120809658082344	[663,577]	[760,899]	8	hSpCas9	negative selection	4525205
43340381	43340403	3	-	27760321	OCIAML2	viability	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.6144545242506418	[58,40]	[29,20]	-6	hSpCas9	negative selection	4525206
43343439	43343461	3	-	27760321	OCIAML2	viability	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	-0.013527686530453664	[726,776]	[522,715]	0	hSpCas9	negative selection	4525207
43303306	43303328	3	+	27760321	MV411	viability	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	-1.2562198120675987	[275,249]	[72,71]	-7	hSpCas9	negative selection	4608666
43303686	43303708	3	+	27760321	MV411	viability	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	0.012297719842368826	[207,154]	[54,216]	0	hSpCas9	negative selection	4608667
43303709	43303731	3	+	27760321	MV411	viability	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.42911838003381564	[663,577]	[348,852]	3	hSpCas9	negative selection	4608668
43340381	43340403	3	-	27760321	MV411	viability	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.40806439929541094	[58,40]	[0,59]	-3	hSpCas9	negative selection	4608669
43343439	43343461	3	-	27760321	MV411	viability	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	1.8234242346679743	[726,776]	[1855,1632]	9	hSpCas9	negative selection	4608670
43303306	43303328	3	+	27760321	HL60	viability	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	-0.06186916379671814	[275,249]	[210,199]	0	hSpCas9	negative selection	4692129
43303686	43303708	3	+	27760321	HL60	viability	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	3.6444952967237043	[207,154]	[2118,1539]	9	hSpCas9	negative selection	4692130
43303709	43303731	3	+	27760321	HL60	viability	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.556779199313956	[663,577]	[873,606]	6	hSpCas9	negative selection	4692131
43340381	43340403	3	-	27760321	HL60	viability	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.9270475799543578	[58,40]	[28,12]	-7	hSpCas9	negative selection	4692132
43343439	43343461	3	-	27760321	HL60	viability	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	-0.24365055599835128	[726,776]	[536,505]	-3	hSpCas9	negative selection	4692133
43303306	43303328	3	+	27760321	HT1080	viability	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	0.8896903232944033	[249,194]	[73,262]	5	hSpCas9	negative selection	4775592
43303686	43303708	3	+	27760321	HT1080	viability	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	0.6578173807285135	[154,120]	[38,138]	3	hSpCas9	negative selection	4775593
43303709	43303731	3	+	27760321	HT1080	viability	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	2.0246363690341984	[577,450]	[969,684]	9	hSpCas9	negative selection	4775594
43340381	43340403	3	-	27760321	HT1080	viability	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-2.1021047041248364	[40,31]	[0,5]	-6	hSpCas9	negative selection	4775595
43343439	43343461	3	-	27760321	HT1080	viability	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	0.31884208129495084	[776,606]	[277,415]	1	hSpCas9	negative selection	4775596
43303306	43303328	3	+	27760321	HT29	viability after 7 days	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	0.4972737914260186	[249,194]	[222,303,649]	7	hSpCas9	negative selection	4859055
43303686	43303708	3	+	27760321	HT29	viability after 7 days	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	1.1148484711835327	[154,120]	[372,404,372]	9	hSpCas9	negative selection	4859056
43303709	43303731	3	+	27760321	HT29	viability after 7 days	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	-0.012475451347983335	[577,450]	[600,713,643]	0	hSpCas9	negative selection	4859057
43340381	43340403	3	-	27760321	HT29	viability after 7 days	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.850813109115486	[40,31]	[33,13,30]	-8	hSpCas9	negative selection	4859058
43343439	43343461	3	-	27760321	HT29	viability after 7 days	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	-0.1829320840217209	[776,606]	[704,848,784]	-3	hSpCas9	negative selection	4859059
43303306	43303328	3	+	27760321	HT29	viability after 25 days	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	0.24849461295445524	[249,194]	[271,157,497]	2	hSpCas9	negative selection	4942518
43303686	43303708	3	+	27760321	HT29	viability after 25 days	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	0.8226585995930721	[154,120]	[335,241,251]	8	hSpCas9	negative selection	4942519
43303709	43303731	3	+	27760321	HT29	viability after 25 days	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.5186827459157274	[577,450]	[829,841,855]	6	hSpCas9	negative selection	4942520
43340381	43340403	3	-	27760321	HT29	viability after 25 days	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.3528584545772673	[40,31]	[31,58,3]	-4	hSpCas9	negative selection	4942521
43343439	43343461	3	-	27760321	HT29	viability after 25 days	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	0.04566158720252467	[776,606]	[794,975,661]	0	hSpCas9	negative selection	4942522
43303306	43303328	3	+	27760321	HT29	viability after 22 days	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	0.46951555460253613	[249,194]	[307,376,384]	5	hSpCas9	negative selection	5025981
43303686	43303708	3	+	27760321	HT29	viability after 22 days	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	0.5869930094597781	[154,120]	[308,172,234]	6	hSpCas9	negative selection	5025982
43303709	43303731	3	+	27760321	HT29	viability after 22 days	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.6097851443581267	[577,450]	[1310,703,694]	6	hSpCas9	negative selection	5025983
43340381	43340403	3	-	27760321	HT29	viability after 22 days	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.27156977784361835	[40,31]	[18,48,85]	3	hSpCas9	negative selection	5025984
43343439	43343461	3	-	27760321	HT29	viability after 22 days	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	-0.3782315241281329	[776,606]	[489,948,408]	-4	hSpCas9	negative selection	5025985
43303306	43303328	3	+	27760321	HT29	viability after 19 days	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	0.22614853939727964	[249,194]	[459,239,212]	2	hSpCas9	negative selection	5109444
43303686	43303708	3	+	27760321	HT29	viability after 19 days	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	0.8334323702554806	[154,120]	[278,301,262]	8	hSpCas9	negative selection	5109445
43303709	43303731	3	+	27760321	HT29	viability after 19 days	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.20788342972126295	[577,450]	[970,635,469]	2	hSpCas9	negative selection	5109446
43340381	43340403	3	-	27760321	HT29	viability after 19 days	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-2.2270893361918196	[40,31]	[17,8,0]	-8	hSpCas9	negative selection	5109447
43343439	43343461	3	-	27760321	HT29	viability after 19 days	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	-0.4406111807764871	[776,606]	[464,855,421]	-4	hSpCas9	negative selection	5109448
43303306	43303328	3	+	27760321	HT29	viability after 16 days	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	0.221211675352615	[249,194]	[347,172,357]	2	hSpCas9	negative selection	5192907
43303686	43303708	3	+	27760321	HT29	viability after 16 days	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	0.48642275690142955	[154,120]	[409,69,190]	5	hSpCas9	negative selection	5192908
43303709	43303731	3	+	27760321	HT29	viability after 16 days	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.2665268481885237	[577,450]	[673,783,614]	3	hSpCas9	negative selection	5192909
43340381	43340403	3	-	27760321	HT29	viability after 16 days	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-2.3952553113804527	[40,31]	[13,2,6]	-8	hSpCas9	negative selection	5192910
43343439	43343461	3	-	27760321	HT29	viability after 16 days	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	-0.3071319571061296	[776,606]	[761,592,535]	-3	hSpCas9	negative selection	5192911
43303306	43303328	3	+	27760321	HT29	viability after 13 days	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	0.20155372733872845	[249,194]	[215,401,273]	2	hSpCas9	negative selection	5276370
43303686	43303708	3	+	27760321	HT29	viability after 13 days	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	1.0839052128827016	[154,120]	[544,242,235]	9	hSpCas9	negative selection	5276371
43303709	43303731	3	+	27760321	HT29	viability after 13 days	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.5431042701902521	[577,450]	[827,910,869]	7	hSpCas9	negative selection	5276372
43340381	43340403	3	-	27760321	HT29	viability after 13 days	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-2.0858919848478417	[40,31]	[1,18,8]	-8	hSpCas9	negative selection	5276373
43343439	43343461	3	-	27760321	HT29	viability after 13 days	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	-0.22166986420207213	[776,606]	[839,706,527]	-3	hSpCas9	negative selection	5276374
43303306	43303328	3	+	27760321	HT29	viability after 10 days	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	-0.13758887828087984	[249,194]	[187,390,183]	-2	hSpCas9	negative selection	5359833
43303686	43303708	3	+	27760321	HT29	viability after 10 days	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	0.7534733127694144	[154,120]	[392,256,221]	8	hSpCas9	negative selection	5359834
43303709	43303731	3	+	27760321	HT29	viability after 10 days	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.5274753430601608	[577,450]	[1146,834,795]	7	hSpCas9	negative selection	5359835
43340381	43340403	3	-	27760321	HT29	viability after 10 days	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.4671732209463415	[40,31]	[12,23,60]	-5	hSpCas9	negative selection	5359836
43343439	43343461	3	-	27760321	HT29	viability after 10 days	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	-0.4533224065982232	[776,606]	[671,710,514]	-5	hSpCas9	negative selection	5359837
43303306	43303328	3	+	27760321	MOLM13	viability	CATGTCTTTACGGGTGAAAAGG	SNRK	ENSG00000163788	-0.5671685082446932	[275,249]	[125,77]	-4	hSpCas9	negative selection	5443296
43303686	43303708	3	+	27760321	MOLM13	viability	CAGCAACAAATTTCAACCAGGG	SNRK	ENSG00000163788	-0.05877614450448321	[207,154]	[171,33]	0	hSpCas9	negative selection	5443297
43303709	43303731	3	+	27760321	MOLM13	viability	AGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.2502656905792663	[663,577]	[304,509]	1	hSpCas9	negative selection	5443298
43340381	43340403	3	-	27760321	MOLM13	viability	GAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.5260319007773329	[58,40]	[0,34]	-3	hSpCas9	negative selection	5443299
43343439	43343461	3	-	27760321	MOLM13	viability	TTGCTCGGGCTTGCAGATCTGG	SNRK	ENSG00000163788	0.006818159737485785	[726,776]	[403,449]	0	hSpCas9	negative selection	5443300
43286612	43286635	3	+	27661255	K562	viability	GGCGGCCGGGAGGGAGTTGTCGG	SNRK	ENSG00000163788	-0.09423354604611145	[350,405]	[329,241]	-3	dCas9-KRAB	negative selection	5513205
43286702	43286725	3	+	27661255	K562	viability	GGCGCGGCGGCCGTAGGCAGGGG	SNRK	ENSG00000163788	0.3981660529322699	[115,157]	[130,153]	9	dCas9-KRAB	negative selection	5513206
43286923	43286946	3	+	27661255	K562	viability	GGCGGGAGCCGTCACTGCGGCGG	SNRK	ENSG00000163788	0.06527590361051372	[482,359]	[419,297]	2	dCas9-KRAB	negative selection	5513207
43286757	43286780	3	-	27661255	K562	viability	GGCGCCCAGCCCGGCAACAGCGG	SNRK	ENSG00000163788	-0.9958953155079464	[562,755]	[238,282]	-8	dCas9-KRAB	negative selection	5513208
43348109	43348132	3	-	27260156	BXPC3	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.18977475116995396	[393]	[536,483,351,495]	4	hSpCas9	negative selection	5572027
43347909	43347932	3	-	27260156	BXPC3	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.02817496717015122	[239]	[260,231,231,257]	0	hSpCas9	negative selection	5572028
43343446	43343469	3	+	27260156	BXPC3	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.5419431027973942	[324]	[474,554,498,437]	9	hSpCas9	negative selection	5572029
43343355	43343378	3	-	27260156	BXPC3	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.18731396763215158	[1142]	[854,853,1237,1312]	-4	hSpCas9	negative selection	5636279
43340440	43340463	3	+	27260156	BXPC3	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.3435318435657871	[345]	[352,472,448,583]	7	hSpCas9	negative selection	5636280
43340381	43340404	3	-	27260156	BXPC3	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.09423396041666443	[159]	[122,186,141,177]	-2	hSpCas9	negative selection	5636281
43348109	43348132	3	-	27260156	A673	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.14985536883595288	[393]	[553,524,556,461]	3	hSpCas9	negative selection	5693278
43347909	43347932	3	-	27260156	A673	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.24511767620809088	[239]	[263,280,200,226]	-6	hSpCas9	negative selection	5693279
43343446	43343469	3	+	27260156	A673	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.5585348819070145	[324]	[587,560,599,548]	9	hSpCas9	negative selection	5693280
43343355	43343378	3	-	27260156	A673	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.1438147874250446	[1142]	[1387,1208,1188,1195]	-4	hSpCas9	negative selection	5757530
43340440	43340463	3	+	27260156	A673	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.45831337675933076	[345]	[600,597,578,502]	9	hSpCas9	negative selection	5757531
43340381	43340404	3	-	27260156	A673	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.1569705230109817	[159]	[212,145,182,150]	-4	hSpCas9	negative selection	5757532
43348109	43348132	3	-	27260156	A375	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.24644527190876597	[393]	[322,505,384,355]	-4	hSpCas9	negative selection	5814529
43347909	43347932	3	-	27260156	A375	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.2901082902490999	[239]	[322,404,184,49]	-4	hSpCas9	negative selection	5814530
43343446	43343469	3	+	27260156	A375	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.6124998840590035	[324]	[521,697,588,531]	8	hSpCas9	negative selection	5814531
43343355	43343378	3	-	27260156	A375	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.4547779426039349	[1142]	[1307,1211,683,750]	-6	hSpCas9	negative selection	5878781
43340440	43340463	3	+	27260156	A375	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.487182298888951	[345]	[671,801,476,369]	7	hSpCas9	negative selection	5878782
43340381	43340404	3	-	27260156	A375	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.19779177428654626	[159]	[150,324,213,184]	3	hSpCas9	negative selection	5878783
43348109	43348132	3	-	27260156	COLO741	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.045205778127100804	[393]	[489,585,393]	-1	hSpCas9	negative selection	5935780
43347909	43347932	3	-	27260156	COLO741	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.6200564066684964	[239]	[191,226,179]	-8	hSpCas9	negative selection	5935781
43343446	43343469	3	+	27260156	COLO741	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	-0.10737794680268675	[324]	[474,344,345]	-2	hSpCas9	negative selection	5935782
43343355	43343378	3	-	27260156	COLO741	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.3631942700010299	[1142]	[1355,1210,874]	-7	hSpCas9	negative selection	6000032
43340440	43340463	3	+	27260156	COLO741	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.3550588921847762	[345]	[849,461,417]	7	hSpCas9	negative selection	6000033
43340381	43340404	3	-	27260156	COLO741	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.1120895242228277	[159]	[185,259,213]	2	hSpCas9	negative selection	6000034
43348109	43348132	3	-	27260156	CAL120	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.321038611030144	[393]	[835,543,492]	5	hSpCas9	negative selection	6057031
43347909	43347932	3	-	27260156	CAL120	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.9425273577298763	[239]	[86,166,200]	-8	hSpCas9	negative selection	6057032
43343446	43343469	3	+	27260156	CAL120	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.19374465999542695	[324]	[390,427,555]	3	hSpCas9	negative selection	6057033
43343355	43343378	3	-	27260156	CAL120	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.6513207519763243	[1142]	[907,803,1002]	-7	hSpCas9	negative selection	6121283
43340440	43340463	3	+	27260156	CAL120	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.48467884050068155	[345]	[592,792,422]	7	hSpCas9	negative selection	6121284
43340381	43340404	3	-	27260156	CAL120	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.048433164345207835	[159]	[285,192,113]	0	hSpCas9	negative selection	6121285
43348109	43348132	3	-	27260156	CADOES1	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.34463766058448575	[393]	[221,328,328,273]	-5	hSpCas9	negative selection	6178282
43347909	43347932	3	-	27260156	CADOES1	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.7124516851964704	[239]	[159,177,119,84]	-8	hSpCas9	negative selection	6178283
43343446	43343469	3	+	27260156	CADOES1	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.41184363091449366	[324]	[375,406,387,438]	6	hSpCas9	negative selection	6178284
43343355	43343378	3	-	27260156	CADOES1	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.13188546839058368	[1142]	[733,1116,999,1032]	-2	hSpCas9	negative selection	6242534
43340440	43340463	3	+	27260156	CADOES1	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.6446372063459979	[345]	[580,608,405,412]	9	hSpCas9	negative selection	6242535
43340381	43340404	3	-	27260156	CADOES1	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.26718903359167445	[159]	[151,241,182,137]	4	hSpCas9	negative selection	6242536
43348109	43348132	3	-	27260156	EWS502	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.12408110108897705	[393]	[547,399,350,511]	2	hSpCas9	negative selection	6299533
43347909	43347932	3	-	27260156	EWS502	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.5096012596238433	[239]	[119,210,141,250]	-7	hSpCas9	negative selection	6299534
43343446	43343469	3	+	27260156	EWS502	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.5360677399485366	[324]	[522,507,425,535]	8	hSpCas9	negative selection	6299535
43343355	43343378	3	-	27260156	EWS502	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.4593228533941782	[1142]	[802,867,913,948]	-7	hSpCas9	negative selection	6363785
43340440	43340463	3	+	27260156	EWS502	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.4752455494646851	[345]	[570,513,498,438]	8	hSpCas9	negative selection	6363786
43340381	43340404	3	-	27260156	EWS502	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	1.0382106519378231	[159]	[738,243,186,161]	9	hSpCas9	negative selection	6363787
43348109	43348132	3	-	27260156	EW8	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.2931080858988431	[393]	[257,333,217,238]	-5	hSpCas9	negative selection	6420784
43347909	43347932	3	-	27260156	EW8	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.4306179153131755	[239]	[163,154,120,142]	-7	hSpCas9	negative selection	6420785
43343446	43343469	3	+	27260156	EW8	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.5527971466936483	[324]	[590,299,348,332]	8	hSpCas9	negative selection	6420786
43343355	43343378	3	-	27260156	EW8	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.2077955365244104	[1142]	[768,849,636,973]	-4	hSpCas9	negative selection	6485036
43340440	43340463	3	+	27260156	EW8	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.6454110428853289	[345]	[528,338,345,563]	9	hSpCas9	negative selection	6485037
43340381	43340404	3	-	27260156	EW8	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.4642284172485307	[159]	[242,61,240,164]	8	hSpCas9	negative selection	6485038
43348109	43348132	3	-	27260156	CORL105	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.2396654224451656	[393]	[611,497,609,471]	4	hSpCas9	negative selection	6542035
43347909	43347932	3	-	27260156	CORL105	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.30421647896860216	[239]	[201,291,207,202]	-5	hSpCas9	negative selection	6542036
43343446	43343469	3	+	27260156	CORL105	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.5887456949610294	[324]	[466,500,742,601]	9	hSpCas9	negative selection	6542037
43343355	43343378	3	-	27260156	CORL105	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.2091883264236738	[1142]	[1291,1164,1128,1043]	-4	hSpCas9	negative selection	6606287
43340440	43340463	3	+	27260156	CORL105	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.40391059483600783	[345]	[530,533,589,496]	7	hSpCas9	negative selection	6606288
43340381	43340404	3	-	27260156	CORL105	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.23990727404555634	[159]	[243,230,305,117]	4	hSpCas9	negative selection	6606289
43348109	43348132	3	-	27260156	HS294T	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.39121290641391626	[393]	[129,146,155,408]	5	hSpCas9	negative selection	6663286
43347909	43347932	3	-	27260156	HS294T	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.12275282044934555	[239]	[51,55,130,109]	-2	hSpCas9	negative selection	6663287
43343446	43343469	3	+	27260156	HS294T	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.5845598032544149	[324]	[187,195,144,230]	7	hSpCas9	negative selection	6663288
43343355	43343378	3	-	27260156	HS294T	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.10784243036898755	[1142]	[517,284,303,548]	-1	hSpCas9	negative selection	6727538
43340440	43340463	3	+	27260156	HS294T	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.7262498078443924	[345]	[169,186,350,174]	8	hSpCas9	negative selection	6727539
43340381	43340404	3	-	27260156	HS294T	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.5718609314038232	[159]	[22,79,47,249]	7	hSpCas9	negative selection	6727540
43348109	43348132	3	-	27260156	HCC44	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.13013735015422795	[393]	[378,396,521,347]	-2	hSpCas9	negative selection	6784537
43347909	43347932	3	-	27260156	HCC44	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.44225129215956116	[239]	[308,189,160,143]	-6	hSpCas9	negative selection	6784538
43343446	43343469	3	+	27260156	HCC44	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.6233976532696649	[324]	[517,638,681,430]	8	hSpCas9	negative selection	6784539
43343355	43343378	3	-	27260156	HCC44	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.4588246110626393	[1142]	[1073,869,1214,673]	-6	hSpCas9	negative selection	6848789
43340440	43340463	3	+	27260156	HCC44	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.5249680880277121	[345]	[593,535,841,337]	8	hSpCas9	negative selection	6848790
43340381	43340404	3	-	27260156	HCC44	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.3024501767279155	[159]	[233,358,203,76]	5	hSpCas9	negative selection	6848791
43348109	43348132	3	-	27260156	G402	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.10172924644622067	[393]	[677,279,432,423]	-1	hSpCas9	negative selection	6905788
43347909	43347932	3	-	27260156	G402	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.4120587611588793	[239]	[115,182,60,488]	-5	hSpCas9	negative selection	6905789
43343446	43343469	3	+	27260156	G402	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	1.030770960354916	[324]	[544,711,1491,461]	9	hSpCas9	negative selection	6905790
43343355	43343378	3	-	27260156	G402	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.09065984408395478	[1142]	[1888,1312,1044,1081]	-1	hSpCas9	negative selection	6970040
43340440	43340463	3	+	27260156	G402	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.32624827597579364	[345]	[548,504,455,602]	4	hSpCas9	negative selection	6970041
43340381	43340404	3	-	27260156	G402	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.04370990528115559	[159]	[163,294,166,135]	0	hSpCas9	negative selection	6970042
43348109	43348132	3	-	27260156	L33	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.10009414454334187	[393]	[431,172,188,313]	-2	hSpCas9	negative selection	7027039
43347909	43347932	3	-	27260156	L33	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.5175466746262234	[239]	[168,55,112,184]	-8	hSpCas9	negative selection	7027040
43343446	43343469	3	+	27260156	L33	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.4750519765000557	[324]	[405,194,357,357]	8	hSpCas9	negative selection	7027041
43343355	43343378	3	-	27260156	L33	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.2762798255730059	[1142]	[985,372,582,949]	-6	hSpCas9	negative selection	7091291
43340440	43340463	3	+	27260156	L33	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.38023391808184837	[345]	[411,162,272,556]	7	hSpCas9	negative selection	7091292
43340381	43340404	3	-	27260156	L33	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.11197580212757696	[159]	[170,65,87,218]	2	hSpCas9	negative selection	7091293
43348109	43348132	3	-	27260156	K562	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.2152625716077619	[393]	[320,226,340,310]	-3	hSpCas9	negative selection	7148290
43347909	43347932	3	-	27260156	K562	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-1.1048526589215466	[239]	[212,51,89,52]	-8	hSpCas9	negative selection	7148291
43343446	43343469	3	+	27260156	K562	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.41441686085345625	[324]	[529,261,332,412]	5	hSpCas9	negative selection	7148292
43343355	43343378	3	-	27260156	K562	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.5865394353449972	[1142]	[951,812,628,370]	-6	hSpCas9	negative selection	7212542
43340440	43340463	3	+	27260156	K562	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.9754707495112095	[345]	[472,637,966,354]	9	hSpCas9	negative selection	7212543
43340381	43340404	3	-	27260156	K562	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.4863160249069778	[159]	[275,119,145,248]	6	hSpCas9	negative selection	7212544
43348109	43348132	3	-	27260156	HT29	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.25972757367029686	[393]	[507,404,373,327]	-5	hSpCas9	negative selection	7269541
43347909	43347932	3	-	27260156	HT29	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.4668210809664668	[239]	[280,248,177,150]	-7	hSpCas9	negative selection	7269542
43343446	43343469	3	+	27260156	HT29	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.46455927250606066	[324]	[601,570,444,562]	8	hSpCas9	negative selection	7269543
43343355	43343378	3	-	27260156	HT29	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.4336981475077665	[1142]	[1099,1167,1099,786]	-7	hSpCas9	negative selection	7333793
43340440	43340463	3	+	27260156	HT29	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.27544865854269573	[345]	[594,563,528,372]	5	hSpCas9	negative selection	7333794
43340381	43340404	3	-	27260156	HT29	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.29714607599995424	[159]	[322,293,168,185]	6	hSpCas9	negative selection	7333795
43348109	43348132	3	-	27260156	MHHES1	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.010363702227325383	[393]	[345,408,564,442]	0	hSpCas9	negative selection	7390792
43347909	43347932	3	-	27260156	MHHES1	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.3802485824258257	[239]	[157,195,221,235]	-6	hSpCas9	negative selection	7390793
43343446	43343469	3	+	27260156	MHHES1	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.3421606732015502	[324]	[580,480,393,415]	6	hSpCas9	negative selection	7390794
43343355	43343378	3	-	27260156	MHHES1	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.11160980523585273	[1142]	[1546,1301,1070,932]	-2	hSpCas9	negative selection	7455044
43340440	43340463	3	+	27260156	MHHES1	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.4741697054423715	[345]	[548,621,604,415]	8	hSpCas9	negative selection	7455045
43340381	43340404	3	-	27260156	MHHES1	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.11134625305346346	[159]	[170,208,239,160]	2	hSpCas9	negative selection	7455046
43348109	43348132	3	-	27260156	MEWO	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.00908669389711153	[393]	[437,304,369]	0	hSpCas9	negative selection	7512043
43347909	43347932	3	-	27260156	MEWO	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.6453685184259021	[239]	[154,110,166]	-8	hSpCas9	negative selection	7512044
43343446	43343469	3	+	27260156	MEWO	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.46431879372430995	[324]	[470,291,505]	8	hSpCas9	negative selection	7512045
43343355	43343378	3	-	27260156	MEWO	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.10927057435254328	[1142]	[1014,1072,889]	-2	hSpCas9	negative selection	7576295
43340440	43340463	3	+	27260156	MEWO	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.5302535321163384	[345]	[706,418,322]	9	hSpCas9	negative selection	7576296
43340381	43340404	3	-	27260156	MEWO	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.1576526392744153	[159]	[263,72,90]	-3	hSpCas9	negative selection	7576297
43348109	43348132	3	-	27260156	LNCAPCLONEFGC	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.20469467253723317	[393]	[195,256,381,419]	-3	hSpCas9	negative selection	7633294
43347909	43347932	3	-	27260156	LNCAPCLONEFGC	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.5430097003089256	[239]	[108,203,196,90]	-7	hSpCas9	negative selection	7633295
43343446	43343469	3	+	27260156	LNCAPCLONEFGC	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.7296541032954373	[324]	[606,344,618,407]	9	hSpCas9	negative selection	7633296
43343355	43343378	3	-	27260156	LNCAPCLONEFGC	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.7180099901759428	[1142]	[720,523,692,593]	-8	hSpCas9	negative selection	7697546
43340440	43340463	3	+	27260156	LNCAPCLONEFGC	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.3048232000126526	[345]	[424,284,289,539]	5	hSpCas9	negative selection	7697547
43340381	43340404	3	-	27260156	LNCAPCLONEFGC	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.5477484256624718	[159]	[205,210,194,232]	8	hSpCas9	negative selection	7697548
43348109	43348132	3	-	27260156	PANC0327	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.6424132704976571	[393]	[439,694,443,577]	8	hSpCas9	negative selection	7754545
43347909	43347932	3	-	27260156	PANC0327	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.4254236914483931	[239]	[197,166,103,167]	-6	hSpCas9	negative selection	7754546
43343446	43343469	3	+	27260156	PANC0327	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.19184551797738625	[324]	[193,268,530,321]	3	hSpCas9	negative selection	7754547
43343355	43343378	3	-	27260156	PANC0327	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.7254165351194469	[1142]	[673,730,549,490]	-7	hSpCas9	negative selection	7818797
43340440	43340463	3	+	27260156	PANC0327	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.5977682898786467	[345]	[751,311,557,281]	8	hSpCas9	negative selection	7818798
43340381	43340404	3	-	27260156	PANC0327	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.3056918627472107	[159]	[163,288,119,113]	4	hSpCas9	negative selection	7818799
43348109	43348132	3	-	27260156	NCIH2009	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.031376512890882335	[393]	[683,440,587]	0	hSpCas9	negative selection	7875796
43347909	43347932	3	-	27260156	NCIH2009	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.28473347354972334	[239]	[302,263,263]	-4	hSpCas9	negative selection	7875797
43343446	43343469	3	+	27260156	NCIH2009	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.4175849607057639	[324]	[648,544,633]	6	hSpCas9	negative selection	7875798
43343355	43343378	3	-	27260156	NCIH2009	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.8776175100929591	[1142]	[1035,923,677]	-8	hSpCas9	negative selection	7940048
43340440	43340463	3	+	27260156	NCIH2009	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.3019501004046232	[345]	[681,533,588]	4	hSpCas9	negative selection	7940049
43340381	43340404	3	-	27260156	NCIH2009	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.17580531482074946	[159]	[210,139,245]	-2	hSpCas9	negative selection	7940050
43348109	43348132	3	-	27260156	NCIH1373	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.5062485021966693	[393]	[703,605,393,218]	5	hSpCas9	negative selection	7997047
43347909	43347932	3	-	27260156	NCIH1373	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.6527482919975127	[239]	[199,191,196,23]	-6	hSpCas9	negative selection	7997048
43343446	43343469	3	+	27260156	NCIH1373	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.6026948155808034	[324]	[538,667,553,111]	6	hSpCas9	negative selection	7997049
43343355	43343378	3	-	27260156	NCIH1373	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.5589324814040705	[1142]	[1053,778,798,231]	-5	hSpCas9	negative selection	8061299
43340440	43340463	3	+	27260156	NCIH1373	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.8765936425050536	[345]	[1144,850,409,126]	8	hSpCas9	negative selection	8061300
43340381	43340404	3	-	27260156	NCIH1373	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.5668471938568597	[159]	[331,246,186,81]	5	hSpCas9	negative selection	8061301
43348109	43348132	3	-	27260156	PATU8902	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.2798112939932115	[393]	[409,295,578,490]	-3	hSpCas9	negative selection	8118298
43347909	43347932	3	-	27260156	PATU8902	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.9467336125858303	[239]	[135,170,191,190]	-7	hSpCas9	negative selection	8118299
43343446	43343469	3	+	27260156	PATU8902	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.5651903499107133	[324]	[476,885,560,795]	6	hSpCas9	negative selection	8118300
43343355	43343378	3	-	27260156	PATU8902	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.7524981552808929	[1142]	[912,513,876,1557]	-6	hSpCas9	negative selection	8182550
43340440	43340463	3	+	27260156	PATU8902	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.5079274544135874	[345]	[514,778,153,1528]	5	hSpCas9	negative selection	8182551
43340381	43340404	3	-	27260156	PATU8902	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.9326985485313365	[159]	[532,520,275,402]	8	hSpCas9	negative selection	8182552
43348109	43348132	3	-	27260156	PANC1	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.337274264634814	[393]	[417,275,181,199]	-5	hSpCas9	negative selection	8239549
43347909	43347932	3	-	27260156	PANC1	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.04404108678213836	[239]	[236,293,142,148]	0	hSpCas9	negative selection	8239550
43343446	43343469	3	+	27260156	PANC1	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.6212610501358837	[324]	[321,558,426,430]	8	hSpCas9	negative selection	8239551
43343355	43343378	3	-	27260156	PANC1	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.23565929136080865	[1142]	[675,1198,891,661]	-4	hSpCas9	negative selection	8303801
43340440	43340463	3	+	27260156	PANC1	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.635541691123086	[345]	[642,503,386,330]	8	hSpCas9	negative selection	8303802
43340381	43340404	3	-	27260156	PANC1	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.3355914668883886	[159]	[252,160,178,104]	5	hSpCas9	negative selection	8303803
43348109	43348132	3	-	27260156	PANC0813	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.04810478618055619	[393]	[587,420,655,270]	0	hSpCas9	negative selection	8360800
43347909	43347932	3	-	27260156	PANC0813	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.5103358913148346	[239]	[261,157,209,168]	-6	hSpCas9	negative selection	8360801
43343446	43343469	3	+	27260156	PANC0813	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.2390231156125473	[324]	[614,413,385,403]	4	hSpCas9	negative selection	8360802
43343355	43343378	3	-	27260156	PANC0813	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.815806775931289	[1142]	[856,685,900,622]	-8	hSpCas9	negative selection	8425052
43340440	43340463	3	+	27260156	PANC0813	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.1343504111727949	[345]	[665,261,429,445]	2	hSpCas9	negative selection	8425053
43340381	43340404	3	-	27260156	PANC0813	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.006195488036941921	[159]	[242,163,204,149]	0	hSpCas9	negative selection	8425054
43348109	43348132	3	-	27260156	RDES	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.02790209390031939	[393]	[347,398,471,594]	0	hSpCas9	negative selection	8482051
43347909	43347932	3	-	27260156	RDES	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.41913587734938695	[239]	[156,193,255,229]	-6	hSpCas9	negative selection	8482052
43343446	43343469	3	+	27260156	RDES	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.339385347895095	[324]	[389,469,532,509]	5	hSpCas9	negative selection	8482053
43343355	43343378	3	-	27260156	RDES	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.10440800706418085	[1142]	[979,1416,1058,1459]	-2	hSpCas9	negative selection	8546303
43340440	43340463	3	+	27260156	RDES	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.5010441168759239	[345]	[401,580,675,623]	7	hSpCas9	negative selection	8546304
43340381	43340404	3	-	27260156	RDES	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.43045895888100905	[159]	[185,191,264,381]	7	hSpCas9	negative selection	8546305
43348109	43348132	3	-	27260156	PC3	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.10328176081433238	[393]	[140,311,904,394]	-2	hSpCas9	negative selection	8603302
43347909	43347932	3	-	27260156	PC3	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.6458089412282391	[239]	[98,173,204,160]	-9	hSpCas9	negative selection	8603303
43343446	43343469	3	+	27260156	PC3	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.43926955323799793	[324]	[347,425,605,428]	8	hSpCas9	negative selection	8603304
43343355	43343378	3	-	27260156	PC3	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.16342419112657436	[1142]	[753,999,1818,799]	-4	hSpCas9	negative selection	8667554
43340440	43340463	3	+	27260156	PC3	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.415797393021165	[345]	[351,479,782,337]	8	hSpCas9	negative selection	8667555
43340381	43340404	3	-	27260156	PC3	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.25101366266834857	[159]	[60,211,217,92]	-5	hSpCas9	negative selection	8667556
43348109	43348132	3	-	27260156	PATU8988T	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.19084180825782615	[393]	[340,451,283,684]	3	hSpCas9	negative selection	8724553
43347909	43347932	3	-	27260156	PATU8988T	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.8862838432581344	[239]	[69,129,161,140]	-8	hSpCas9	negative selection	8724554
43343446	43343469	3	+	27260156	PATU8988T	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.500686229407496	[324]	[241,506,598,431]	8	hSpCas9	negative selection	8724555
43343355	43343378	3	-	27260156	PATU8988T	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.22888925096524426	[1142]	[868,1122,1055,718]	-4	hSpCas9	negative selection	8788805
43340440	43340463	3	+	27260156	PATU8988T	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.5885056708578927	[345]	[658,559,356,436]	8	hSpCas9	negative selection	8788806
43340381	43340404	3	-	27260156	PATU8988T	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.2553431463994551	[159]	[56,187,294,197]	4	hSpCas9	negative selection	8788807
43348109	43348132	3	-	27260156	T47D	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.11081921667515776	[393]	[487,388,419,405]	-2	hSpCas9	negative selection	8845804
43347909	43347932	3	-	27260156	T47D	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.98233876248045	[239]	[120,162,140,138]	-9	hSpCas9	negative selection	8845805
43343446	43343469	3	+	27260156	T47D	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.44806398686195836	[324]	[565,428,500,579]	8	hSpCas9	negative selection	8845806
43343355	43343378	3	-	27260156	T47D	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.3984321002628397	[1142]	[918,994,1052,1075]	-7	hSpCas9	negative selection	8910056
43340440	43340463	3	+	27260156	T47D	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.36228605275047215	[345]	[602,449,545,477]	7	hSpCas9	negative selection	8910057
43340381	43340404	3	-	27260156	T47D	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.3264671292238588	[159]	[217,146,232,347]	7	hSpCas9	negative selection	8910058
43348109	43348132	3	-	27260156	SU8686	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.008083908694987818	[393]	[311,383,326,563]	0	hSpCas9	negative selection	8967055
43347909	43347932	3	-	27260156	SU8686	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.6725446065151583	[239]	[90,168,137,211]	-7	hSpCas9	negative selection	8967056
43343446	43343469	3	+	27260156	SU8686	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.27744274925701745	[324]	[308,326,482,473]	5	hSpCas9	negative selection	8967057
43343355	43343378	3	-	27260156	SU8686	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.682946510119718	[1142]	[639,548,797,891]	-7	hSpCas9	negative selection	9031307
43340440	43340463	3	+	27260156	SU8686	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.24375158254817386	[345]	[287,403,442,519]	4	hSpCas9	negative selection	9031308
43340381	43340404	3	-	27260156	SU8686	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.2231476074015304	[159]	[151,168,244,179]	4	hSpCas9	negative selection	9031309
43348109	43348132	3	-	27260156	SKES1	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.2640877035324507	[393]	[450,378,203,299]	-5	hSpCas9	negative selection	9088306
43347909	43347932	3	-	27260156	SKES1	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-1.268974279556548	[239]	[77,106,149,62]	-9	hSpCas9	negative selection	9088307
43343446	43343469	3	+	27260156	SKES1	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.5690433825680971	[324]	[547,482,415,481]	9	hSpCas9	negative selection	9088308
43343355	43343378	3	-	27260156	SKES1	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.22812696881432504	[1142]	[1193,1240,814,727]	-5	hSpCas9	negative selection	9152558
43340440	43340463	3	+	27260156	SKES1	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.4805055745947793	[345]	[538,429,534,424]	8	hSpCas9	negative selection	9152559
43340381	43340404	3	-	27260156	SKES1	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.10396056704948609	[159]	[185,217,120,167]	2	hSpCas9	negative selection	9152560
43348109	43348132	3	-	27260156	TOV112D	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	0.04270297252383359	[393]	[362,592,397,315]	0	hSpCas9	negative selection	9209557
43347909	43347932	3	-	27260156	TOV112D	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.0016645964976713667	[239]	[188,228,187,343]	0	hSpCas9	negative selection	9209558
43343446	43343469	3	+	27260156	TOV112D	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.6340422772157146	[324]	[438,568,374,642]	9	hSpCas9	negative selection	9209559
43343355	43343378	3	-	27260156	TOV112D	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.26451217427244744	[1142]	[1073,1124,821,844]	-5	hSpCas9	negative selection	9273809
43340440	43340463	3	+	27260156	TOV112D	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.5490986904418766	[345]	[569,597,306,577]	8	hSpCas9	negative selection	9273810
43340381	43340404	3	-	27260156	TOV112D	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.125391943863973	[159]	[159,213,83,146]	-2	hSpCas9	negative selection	9273811
43348109	43348132	3	-	27260156	TC71	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.01656448318560394	[393]	[453,361,391,464]	0	hSpCas9	negative selection	9330808
43347909	43347932	3	-	27260156	TC71	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.9844577808457249	[239]	[107,107,144,160]	-9	hSpCas9	negative selection	9330809
43343446	43343469	3	+	27260156	TC71	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.46010698041450315	[324]	[406,552,464,494]	9	hSpCas9	negative selection	9330810
43343355	43343378	3	-	27260156	TC71	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.22026621415710945	[1142]	[829,1098,1017,1279]	-5	hSpCas9	negative selection	9395060
43340440	43340463	3	+	27260156	TC71	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.19628476048970692	[345]	[515,408,331,444]	5	hSpCas9	negative selection	9395061
43340381	43340404	3	-	27260156	TC71	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	-0.14113968225684048	[159]	[211,124,145,136]	-4	hSpCas9	negative selection	9395062
43348109	43348132	3	-	27260156	TC32	viability	GCGTGTGGTACCCGATGTATTGG	SNRK	ENSG00000163788	-0.21445738214031607	[393]	[353,123,449,429]	-4	hSpCas9	negative selection	9452059
43347909	43347932	3	-	27260156	TC32	viability	TATCTTTATCGAGCCGCCGCCGG	SNRK	ENSG00000163788	-0.3432899573673689	[239]	[222,206,115,120]	-6	hSpCas9	negative selection	9452060
43343446	43343469	3	+	27260156	TC32	viability	TGCAAGCCCGAGCAATATCAAGG	SNRK	ENSG00000163788	0.4978173941520899	[324]	[370,425,434,477]	8	hSpCas9	negative selection	9452061
43343355	43343378	3	-	27260156	TC32	viability	TGTGATATGGTTATACCTGTTGG	SNRK	ENSG00000163788	-0.1737094562628818	[1142]	[900,882,1137,886]	-3	hSpCas9	negative selection	9516311
43340440	43340463	3	+	27260156	TC32	viability	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.4167424740394942	[345]	[438,267,607,491]	7	hSpCas9	negative selection	9516312
43340381	43340404	3	-	27260156	TC32	viability	GGAATGTTATACTTTGTAGCTGG	SNRK	ENSG00000163788	0.661498609335561	[159]	[309,221,149,233]	9	hSpCas9	negative selection	9516313
43303286	43303309	3	-	27869803	HPAFII	viability after 27 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.5019062320100269	[297]	[180,51,NaN]	-4	hSpCas9	negative selection	9584798
43332191	43332214	3	-	27869803	HPAFII	viability after 27 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	1.1139838374793265	[407]	[424,496,NaN]	8	hSpCas9	negative selection	9584799
43340440	43340463	3	+	27869803	HPAFII	viability after 27 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	1.062834194149739	[418]	[337,561,NaN]	8	hSpCas9	negative selection	9584800
43340490	43340513	3	-	27869803	HPAFII	viability after 27 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.31353223751157067	[227]	[66,120,NaN]	-2	hSpCas9	negative selection	9584801
43347951	43347974	3	+	27869803	HPAFII	viability after 27 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.3784892693802946	[723]	[634,377,NaN]	3	hSpCas9	negative selection	9584802
43303286	43303309	3	-	27869803	HPAFII	viability after 15 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.12543117360639253	[297]	[300,288,NaN]	-1	hSpCas9	negative selection	9667247
43332191	43332214	3	-	27869803	HPAFII	viability after 15 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.47851213073445775	[407]	[790,498,NaN]	5	hSpCas9	negative selection	9667248
43340440	43340463	3	+	27869803	HPAFII	viability after 15 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.05143876272163239	[418]	[367,527,NaN]	0	hSpCas9	negative selection	9667249
43340490	43340513	3	-	27869803	HPAFII	viability after 15 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.8796666446331458	[227]	[237,67,NaN]	-7	hSpCas9	negative selection	9667250
43347951	43347974	3	+	27869803	HPAFII	viability after 15 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.5082209384910299	[723]	[1570,817,NaN]	6	hSpCas9	negative selection	9667251
43303286	43303309	3	-	27869803	ASPC1	viability after 36 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	1.8460820879398505	[747]	[975,853,969]	9	hSpCas9	negative selection	9749696
43332191	43332214	3	-	27869803	ASPC1	viability after 36 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.19589405995403697	[852]	[426,431,204]	2	hSpCas9	negative selection	9749697
43340440	43340463	3	+	27869803	ASPC1	viability after 36 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.7417208301642031	[949]	[108,206,251]	-6	hSpCas9	negative selection	9749698
43340490	43340513	3	-	27869803	ASPC1	viability after 36 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	0.413289037977484	[577]	[233,176,362]	4	hSpCas9	negative selection	9749699
43347951	43347974	3	+	27869803	ASPC1	viability after 36 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.06953379877724819	[2099]	[918,718,695]	0	hSpCas9	negative selection	9749700
43303286	43303309	3	-	27869803	PATU8988S	viability after 35 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.04643397302452898	[602]	[307,161,NaN]	0	hSpCas9	negative selection	9832145
43332191	43332214	3	-	27869803	PATU8988S	viability after 35 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.5200498851694774	[821]	[580,367,NaN]	6	hSpCas9	negative selection	9832146
43340440	43340463	3	+	27869803	PATU8988S	viability after 35 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.09871312262928988	[888]	[339,426,NaN]	1	hSpCas9	negative selection	9832147
43340490	43340513	3	-	27869803	PATU8988S	viability after 35 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.30749768695204976	[483]	[162,151,NaN]	-3	hSpCas9	negative selection	9832148
43347951	43347974	3	+	27869803	PATU8988S	viability after 35 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.18183164149973696	[1623]	[707,775,NaN]	2	hSpCas9	negative selection	9832149
43303286	43303309	3	-	27869803	PATU8988S	viability after 31 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.07844202045267581	[602]	[241,268,NaN]	1	hSpCas9	negative selection	9914594
43332191	43332214	3	-	27869803	PATU8988S	viability after 31 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.6458220249293384	[821]	[485,546,NaN]	7	hSpCas9	negative selection	9914595
43340440	43340463	3	+	27869803	PATU8988S	viability after 31 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	-0.1608722349514703	[888]	[313,320,NaN]	-2	hSpCas9	negative selection	9914596
43340490	43340513	3	-	27869803	PATU8988S	viability after 31 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.1806785073347676	[483]	[142,204,NaN]	-2	hSpCas9	negative selection	9914597
43347951	43347974	3	+	27869803	PATU8988S	viability after 31 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.1595757359124148	[1623]	[611,864,NaN]	2	hSpCas9	negative selection	9914598
43303286	43303309	3	-	27869803	HPAFII	viability after 35 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.7131461668149235	[297]	[139,37,NaN]	-4	hSpCas9	negative selection	9997043
43332191	43332214	3	-	27869803	HPAFII	viability after 35 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	1.0744823653882118	[407]	[402,470,NaN]	7	hSpCas9	negative selection	9997044
43340440	43340463	3	+	27869803	HPAFII	viability after 35 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.9741186712715147	[418]	[268,582,NaN]	6	hSpCas9	negative selection	9997045
43340490	43340513	3	-	27869803	HPAFII	viability after 35 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-1.0048652082108902	[227]	[33,83,NaN]	-5	hSpCas9	negative selection	9997046
43347951	43347974	3	+	27869803	HPAFII	viability after 35 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.6632426555620365	[723]	[515,652,NaN]	4	hSpCas9	negative selection	9997047
43303286	43303309	3	-	27869803	HPAFII	viability after 31 days	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.6641121867494322	[297]	[139,67,NaN]	-4	hSpCas9	negative selection	10079492
43332191	43332214	3	-	27869803	HPAFII	viability after 31 days	GCCCACACACCAACATGAAAAGG	SNRK	ENSG00000163788	0.8796010427078949	[407]	[382,462,NaN]	6	hSpCas9	negative selection	10079493
43340440	43340463	3	+	27869803	HPAFII	viability after 31 days	CAACAGCATCATTCAGCGCATGG	SNRK	ENSG00000163788	0.9508599537663328	[418]	[343,574,NaN]	7	hSpCas9	negative selection	10079494
43340490	43340513	3	-	27869803	HPAFII	viability after 31 days	GGCATTGACGTACTCTACAATGG	SNRK	ENSG00000163788	-0.7744146891605406	[227]	[36,115,NaN]	-5	hSpCas9	negative selection	10079495
43347951	43347974	3	+	27869803	HPAFII	viability after 31 days	GCACCGACGGGATAGCAGCGAGG	SNRK	ENSG00000163788	0.2981343527348965	[723]	[523,472,NaN]	2	hSpCas9	negative selection	10079496
43303202	43303225	3	+	28162770	P31FUJ	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	-0.22909823565095988	[388]	[389]	-2	hSpCas9	negative selection	10239839
43332282	43332305	3	-	28162770	P31FUJ	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	1.6125858496378132	[122]	[441]	9	hSpCas9	negative selection	10239840
43303708	43303731	3	+	28162770	P31FUJ	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.2165051969492114	[207]	[283]	2	hSpCas9	negative selection	10239841
43303269	43303292	3	+	28162770	P31FUJ	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.7828623907489138	[228]	[462]	8	hSpCas9	negative selection	10239842
43303527	43303550	3	+	28162770	P31FUJ	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	0.9090051219247828	[212]	[469]	9	hSpCas9	negative selection	10239843
43303286	43303309	3	-	28162770	P31FUJ	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.893514245367022	[152]	[333]	8	hSpCas9	negative selection	10239844
43332216	43332239	3	-	28162770	P31FUJ	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.444939979512756	[546]	[874]	5	hSpCas9	negative selection	10239845
43340354	43340377	3	-	28162770	P31FUJ	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.35997133347567845	[306]	[462]	4	hSpCas9	negative selection	10239846
43340304	43340327	3	+	28162770	P31FUJ	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	0.0057098822853460796	[444]	[524]	0	hSpCas9	negative selection	10239847
43303771	43303794	3	+	28162770	P31FUJ	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	-0.067665441821112	[502]	[563]	0	hSpCas9	negative selection	10239848
43303202	43303225	3	+	28162770	TF1	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	NaN	[NaN]	[239]	1	hSpCas9	negative selection	10409205
43332282	43332305	3	-	28162770	TF1	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10409206
43303708	43303731	3	+	28162770	TF1	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	NaN	[NaN]	[345]	1	hSpCas9	negative selection	10409207
43303269	43303292	3	+	28162770	TF1	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	NaN	[NaN]	[253]	1	hSpCas9	negative selection	10409208
43303527	43303550	3	+	28162770	TF1	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	NaN	[NaN]	[276]	1	hSpCas9	negative selection	10409209
43303286	43303309	3	-	28162770	TF1	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	NaN	[NaN]	[164]	1	hSpCas9	negative selection	10409210
43332216	43332239	3	-	28162770	TF1	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	NaN	[NaN]	[713]	1	hSpCas9	negative selection	10409211
43340354	43340377	3	-	28162770	TF1	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	NaN	[NaN]	[483]	1	hSpCas9	negative selection	10409212
43340304	43340327	3	+	28162770	TF1	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	NaN	[NaN]	[497]	1	hSpCas9	negative selection	10409213
43303771	43303794	3	+	28162770	TF1	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	NaN	[NaN]	[760]	1	hSpCas9	negative selection	10409214
43303202	43303225	3	+	28162770	SKM1	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	1.0359792971055666	[103]	[376]	8	hSpCas9	negative selection	10578571
43332282	43332305	3	-	28162770	SKM1	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	1.281091794942098	[26]	[115]	9	hSpCas9	negative selection	10578572
43303708	43303731	3	+	28162770	SKM1	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	1.2381192944155655	[46]	[195]	9	hSpCas9	negative selection	10578573
43303269	43303292	3	+	28162770	SKM1	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.9449011802983045	[61]	[210]	8	hSpCas9	negative selection	10578574
43303527	43303550	3	+	28162770	SKM1	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	1.2304657218721302	[80]	[335]	9	hSpCas9	negative selection	10578575
43303286	43303309	3	-	28162770	SKM1	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	1.7387132564524732	[49]	[294]	9	hSpCas9	negative selection	10578576
43332216	43332239	3	-	28162770	SKM1	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	1.5858760096839724	[100]	[535]	9	hSpCas9	negative selection	10578577
43340354	43340377	3	-	28162770	SKM1	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	1.1736462774382872	[82]	[330]	9	hSpCas9	negative selection	10578578
43340304	43340327	3	+	28162770	SKM1	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	1.2438003603737406	[74]	[313]	9	hSpCas9	negative selection	10578579
43303771	43303794	3	+	28162770	SKM1	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	0.8201047098027592	[131]	[411]	7	hSpCas9	negative selection	10578580
43303202	43303225	3	+	28162770	SKM1	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	1.0359792971055666	[103]	[376]	8	hSpCas9	negative selection	10747937
43332282	43332305	3	-	28162770	SKM1	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	1.281091794942098	[26]	[115]	9	hSpCas9	negative selection	10747938
43303708	43303731	3	+	28162770	SKM1	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	1.2381192944155655	[46]	[195]	9	hSpCas9	negative selection	10747939
43303269	43303292	3	+	28162770	SKM1	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.9449011802983045	[61]	[210]	8	hSpCas9	negative selection	10747940
43303527	43303550	3	+	28162770	SKM1	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	1.2304657218721302	[80]	[335]	9	hSpCas9	negative selection	10747941
43303286	43303309	3	-	28162770	SKM1	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	1.7387132564524732	[49]	[294]	9	hSpCas9	negative selection	10747942
43332216	43332239	3	-	28162770	SKM1	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	1.5858760096839724	[100]	[535]	9	hSpCas9	negative selection	10747943
43340354	43340377	3	-	28162770	SKM1	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	1.1736462774382872	[82]	[330]	9	hSpCas9	negative selection	10747944
43340304	43340327	3	+	28162770	SKM1	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	1.2438003603737406	[74]	[313]	9	hSpCas9	negative selection	10747945
43303771	43303794	3	+	28162770	SKM1	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	0.8201047098027592	[131]	[411]	7	hSpCas9	negative selection	10747946
43303202	43303225	3	+	28162770	PL21	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	0.3804714309928644	[352]	[199]	3	hSpCas9	negative selection	10917303
43332282	43332305	3	-	28162770	PL21	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	-1.032521142300955	[93]	[19]	-6	hSpCas9	negative selection	10917304
43303708	43303731	3	+	28162770	PL21	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.8972124815320135	[263]	[213]	7	hSpCas9	negative selection	10917305
43303269	43303292	3	+	28162770	PL21	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	-0.09181640064698321	[261]	[106]	0	hSpCas9	negative selection	10917306
43303527	43303550	3	+	28162770	PL21	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	-0.539797546208177	[323]	[96]	-4	hSpCas9	negative selection	10917307
43303286	43303309	3	-	28162770	PL21	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.00020204398056808404	[169]	[73]	0	hSpCas9	negative selection	10917308
43332216	43332239	3	-	28162770	PL21	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.20474151644832883	[312]	[156]	1	hSpCas9	negative selection	10917309
43340354	43340377	3	-	28162770	PL21	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.8369888568754446	[354]	[275]	7	hSpCas9	negative selection	10917310
43340304	43340327	3	+	28162770	PL21	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	0.4869226230957229	[240]	[146]	4	hSpCas9	negative selection	10917311
43303771	43303794	3	+	28162770	PL21	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	0.041655553583722194	[470]	[210]	0	hSpCas9	negative selection	10917312
43303202	43303225	3	+	28162770	P31FUJ	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	-0.22909823565095988	[388]	[389]	-2	hSpCas9	negative selection	11086669
43332282	43332305	3	-	28162770	P31FUJ	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	1.6125858496378132	[122]	[441]	9	hSpCas9	negative selection	11086670
43303708	43303731	3	+	28162770	P31FUJ	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.2165051969492114	[207]	[283]	2	hSpCas9	negative selection	11086671
43303269	43303292	3	+	28162770	P31FUJ	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.7828623907489138	[228]	[462]	8	hSpCas9	negative selection	11086672
43303527	43303550	3	+	28162770	P31FUJ	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	0.9090051219247828	[212]	[469]	9	hSpCas9	negative selection	11086673
43303286	43303309	3	-	28162770	P31FUJ	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.893514245367022	[152]	[333]	8	hSpCas9	negative selection	11086674
43332216	43332239	3	-	28162770	P31FUJ	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.444939979512756	[546]	[874]	5	hSpCas9	negative selection	11086675
43340354	43340377	3	-	28162770	P31FUJ	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.35997133347567845	[306]	[462]	4	hSpCas9	negative selection	11086676
43340304	43340327	3	+	28162770	P31FUJ	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	0.0057098822853460796	[444]	[524]	0	hSpCas9	negative selection	11086677
43303771	43303794	3	+	28162770	P31FUJ	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	-0.067665441821112	[502]	[563]	0	hSpCas9	negative selection	11086678
43303202	43303225	3	+	28162770	OCIAML5	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	-0.38615674178660414	[201]	[278]	-3	hSpCas9	negative selection	11256035
43332282	43332305	3	-	28162770	OCIAML5	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	0.2299691980020146	[93]	[198]	2	hSpCas9	negative selection	11256036
43303708	43303731	3	+	28162770	OCIAML5	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.7463164456194807	[106]	[323]	6	hSpCas9	negative selection	11256037
43303269	43303292	3	+	28162770	OCIAML5	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.6490643390536883	[123]	[350]	5	hSpCas9	negative selection	11256038
43303527	43303550	3	+	28162770	OCIAML5	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	0.5323629424844508	[130]	[341]	4	hSpCas9	negative selection	11256039
43303286	43303309	3	-	28162770	OCIAML5	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.7328959298571591	[72]	[218]	6	hSpCas9	negative selection	11256040
43332216	43332239	3	-	28162770	OCIAML5	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.4556857552589979	[224]	[556]	4	hSpCas9	negative selection	11256041
43340354	43340377	3	-	28162770	OCIAML5	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.7075106114372456	[171]	[506]	6	hSpCas9	negative selection	11256042
43340304	43340327	3	+	28162770	OCIAML5	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	-0.2170633876432453	[254]	[395]	-1	hSpCas9	negative selection	11256043
43303771	43303794	3	+	28162770	OCIAML5	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	-0.24998380028859013	[362]	[550]	-2	hSpCas9	negative selection	11256044
43303202	43303225	3	+	28162770	EOL1	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	0.6121634493540429	[677]	[545]	5	hSpCas9	negative selection	11425401
43332282	43332305	3	-	28162770	EOL1	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	2.4782915416809708	[108]	[319]	9	hSpCas9	negative selection	11425402
43303708	43303731	3	+	28162770	EOL1	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	-0.17998281190077223	[371]	[172]	-1	hSpCas9	negative selection	11425403
43303269	43303292	3	+	28162770	EOL1	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	-0.12255200572393965	[466]	[225]	-1	hSpCas9	negative selection	11425404
43303527	43303550	3	+	28162770	EOL1	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	0.3411127405959723	[471]	[314]	3	hSpCas9	negative selection	11425405
43303286	43303309	3	-	28162770	EOL1	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.6576089112808247	[295]	[245]	6	hSpCas9	negative selection	11425406
43332216	43332239	3	-	28162770	EOL1	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	-0.6010104419530262	[451]	[156]	-4	hSpCas9	negative selection	11425407
43340354	43340377	3	-	28162770	EOL1	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.08828015759769181	[440]	[246]	0	hSpCas9	negative selection	11425408
43340304	43340327	3	+	28162770	EOL1	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	-0.5247596297930552	[354]	[129]	-4	hSpCas9	negative selection	11425409
43303771	43303794	3	+	28162770	EOL1	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	-0.25167446833298734	[573]	[253]	-2	hSpCas9	negative selection	11425410
43303202	43303225	3	+	28162770	MOLM13	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	1.2199618681009932	[474]	[799]	8	hSpCas9	negative selection	11594767
43332282	43332305	3	-	28162770	MOLM13	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	1.1743697018429706	[219]	[358]	8	hSpCas9	negative selection	11594768
43303708	43303731	3	+	28162770	MOLM13	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.5107979730138698	[264]	[272]	4	hSpCas9	negative selection	11594769
43303269	43303292	3	+	28162770	MOLM13	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	1.0514573001939818	[344]	[516]	7	hSpCas9	negative selection	11594770
43303527	43303550	3	+	28162770	MOLM13	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	0.9221247685360712	[353]	[484]	7	hSpCas9	negative selection	11594771
43303286	43303309	3	-	28162770	MOLM13	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	2.0999470000010363	[220]	[684]	9	hSpCas9	negative selection	11594772
43332216	43332239	3	-	28162770	MOLM13	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	-0.7788573692842847	[457]	[192]	-4	hSpCas9	negative selection	11594773
43340354	43340377	3	-	28162770	MOLM13	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.24354473387385245	[492]	[421]	1	hSpCas9	negative selection	11594774
43340304	43340327	3	+	28162770	MOLM13	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	-0.36252455629362684	[472]	[265]	-2	hSpCas9	negative selection	11594775
43303771	43303794	3	+	28162770	MOLM13	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	-0.42148111502092167	[664]	[358]	-3	hSpCas9	negative selection	11594776
43303202	43303225	3	+	28162770	HEL	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	-0.11027916745121524	[481]	[285]	-1	hSpCas9	negative selection	11764133
43332282	43332305	3	-	28162770	HEL	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	-0.32519995876734464	[177]	[90]	-2	hSpCas9	negative selection	11764134
43303708	43303731	3	+	28162770	HEL	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.3423912676985076	[281]	[228]	3	hSpCas9	negative selection	11764135
43303269	43303292	3	+	28162770	HEL	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	1.448763468079991	[309]	[541]	9	hSpCas9	negative selection	11764136
43303527	43303550	3	+	28162770	HEL	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	1.1909427827113952	[317]	[464]	9	hSpCas9	negative selection	11764137
43303286	43303309	3	-	28162770	HEL	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.7783939313579233	[212]	[233]	6	hSpCas9	negative selection	11764138
43332216	43332239	3	-	28162770	HEL	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.20269732659161865	[387]	[285]	1	hSpCas9	negative selection	11764139
43340354	43340377	3	-	28162770	HEL	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	-0.042024275711240566	[388]	[241]	0	hSpCas9	negative selection	11764140
43340304	43340327	3	+	28162770	HEL	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	-0.06740297409013929	[372]	[227]	0	hSpCas9	negative selection	11764141
43303771	43303794	3	+	28162770	HEL	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	-0.5631057436968981	[548]	[237]	-4	hSpCas9	negative selection	11764142
43303202	43303225	3	+	28162770	MV411	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	0.5152098756232324	[303]	[365]	4	hSpCas9	negative selection	11933499
43332282	43332305	3	-	28162770	MV411	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	1.0993389117936414	[81]	[147]	8	hSpCas9	negative selection	11933500
43303708	43303731	3	+	28162770	MV411	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	1.340003669518848	[165]	[353]	9	hSpCas9	negative selection	11933501
43303269	43303292	3	+	28162770	MV411	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.9055477242377419	[281]	[444]	7	hSpCas9	negative selection	11933502
43303527	43303550	3	+	28162770	MV411	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	0.6624750500616193	[308]	[411]	6	hSpCas9	negative selection	11933503
43303286	43303309	3	-	28162770	MV411	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.4819028044197983	[135]	[159]	4	hSpCas9	negative selection	11933504
43332216	43332239	3	-	28162770	MV411	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.3048398618276974	[270]	[281]	2	hSpCas9	negative selection	11933505
43340354	43340377	3	-	28162770	MV411	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.6999497554802818	[284]	[389]	6	hSpCas9	negative selection	11933506
43340304	43340327	3	+	28162770	MV411	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	0.16943503878150223	[322]	[305]	1	hSpCas9	negative selection	11933507
43303771	43303794	3	+	28162770	MV411	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	0.15915101836482037	[437]	[411]	1	hSpCas9	negative selection	11933508
43303202	43303225	3	+	28162770	MONOMAC1	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	0.12228945263952873	[221]	[276]	1	hSpCas9	negative selection	12102865
43332282	43332305	3	-	28162770	MONOMAC1	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	0.3334778696392262	[53]	[77]	3	hSpCas9	negative selection	12102866
43303708	43303731	3	+	28162770	MONOMAC1	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.5614084745171041	[119]	[202]	5	hSpCas9	negative selection	12102867
43303269	43303292	3	+	28162770	MONOMAC1	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.7084984689369538	[141]	[265]	6	hSpCas9	negative selection	12102868
43303527	43303550	3	+	28162770	MONOMAC1	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	-0.06579231378130107	[167]	[183]	0	hSpCas9	negative selection	12102869
43303286	43303309	3	-	28162770	MONOMAC1	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	-0.13174538680783446	[107]	[112]	-1	hSpCas9	negative selection	12102870
43332216	43332239	3	-	28162770	MONOMAC1	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.7531528531695053	[220]	[426]	7	hSpCas9	negative selection	12102871
43340354	43340377	3	-	28162770	MONOMAC1	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.7951010351674759	[183]	[365]	7	hSpCas9	negative selection	12102872
43340304	43340327	3	+	28162770	MONOMAC1	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	0.42652089897418044	[208]	[321]	4	hSpCas9	negative selection	12102873
43303771	43303794	3	+	28162770	MONOMAC1	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	-0.03815967251705166	[334]	[373]	0	hSpCas9	negative selection	12102874
43303202	43303225	3	+	28162770	OCIAML2	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	0.06405946899777115	[72]	[422]	0	hSpCas9	negative selection	12272231
43332282	43332305	3	-	28162770	OCIAML2	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	-0.21076269848705043	[18]	[90]	-2	hSpCas9	negative selection	12272232
43303708	43303731	3	+	28162770	OCIAML2	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	0.5753825725146748	[26]	[222]	5	hSpCas9	negative selection	12272233
43303269	43303292	3	+	28162770	OCIAML2	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.5393542633304608	[53]	[434]	5	hSpCas9	negative selection	12272234
43303527	43303550	3	+	28162770	OCIAML2	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	-0.42000375217219316	[62]	[260]	-3	hSpCas9	negative selection	12272235
43303286	43303309	3	-	28162770	OCIAML2	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	0.6102901701414061	[25]	[219]	6	hSpCas9	negative selection	12272236
43332216	43332239	3	-	28162770	OCIAML2	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.5095616936776586	[54]	[433]	5	hSpCas9	negative selection	12272237
43340354	43340377	3	-	28162770	OCIAML2	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.110449240991767	[61]	[370]	1	hSpCas9	negative selection	12272238
43340304	43340327	3	+	28162770	OCIAML2	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	-0.11307782062407756	[55]	[286]	-1	hSpCas9	negative selection	12272239
43303771	43303794	3	+	28162770	OCIAML2	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	0.4091671094840821	[85]	[632]	4	hSpCas9	negative selection	12272240
43303202	43303225	3	+	28162770	OCIAML3	viability	GCATGGCAGGATTTAAGCGAGGG	SNRK	ENSG00000163788	0.5644217222803197	[83]	[374]	5	hSpCas9	negative selection	12441597
43332282	43332305	3	-	28162770	OCIAML3	viability	CACTCTTTAGACACATGGGATGG	SNRK	ENSG00000163788	-1.2069845172149158	[38]	[50]	-7	hSpCas9	negative selection	12441598
43303708	43303731	3	+	28162770	OCIAML3	viability	AAGAAGCTCACTACAAGCTGTGG	SNRK	ENSG00000163788	1.2364308948464824	[61]	[440]	8	hSpCas9	negative selection	12441599
43303269	43303292	3	+	28162770	OCIAML3	viability	GGGTCGAGGCCATTTTGCCGTGG	SNRK	ENSG00000163788	0.7864161038733436	[57]	[301]	7	hSpCas9	negative selection	12441600
43303527	43303550	3	+	28162770	OCIAML3	viability	GGAGGGTCTTAATGAAGACTTGG	SNRK	ENSG00000163788	0.5878306826616498	[66]	[303]	5	hSpCas9	negative selection	12441601
43303286	43303309	3	-	28162770	OCIAML3	viability	ATGCCTGGCAAGTTTAACCACGG	SNRK	ENSG00000163788	1.3445918150116936	[41]	[321]	9	hSpCas9	negative selection	12441602
43332216	43332239	3	-	28162770	OCIAML3	viability	TCATTGGCTTCTTGAAAGGGCGG	SNRK	ENSG00000163788	0.5348223400207892	[90]	[397]	5	hSpCas9	negative selection	12441603
43340354	43340377	3	-	28162770	OCIAML3	viability	GGGTCCACTCCCTGAAGCCAAGG	SNRK	ENSG00000163788	0.5971338470278451	[89]	[410]	5	hSpCas9	negative selection	12441604
43340304	43340327	3	+	28162770	OCIAML3	viability	TACAGAGAGATCCCAAGAGAAGG	SNRK	ENSG00000163788	1.0540649042516312	[81]	[513]	8	hSpCas9	negative selection	12441605
43303771	43303794	3	+	28162770	OCIAML3	viability	GAGTATGATGCACCTGCAGTAGG	SNRK	ENSG00000163788	1.054901777176847	[113]	[714]	8	hSpCas9	negative selection	12441606