Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6692
• Symbol:SPINT1
• Description:serine peptidase inhibitor, Kunitz type 1

DataSource: http://genomecrispr.dkfz.de/#!/results/SPINT1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
40844610	40844633	15	-	26472758	Jiyoye	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	0.8415782056516482	[73]	[99]	6	hSpCas9	negative selection	155392
40855938	40855961	15	-	26472758	Jiyoye	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	-0.25178770065905964	[59]	[37]	-2	hSpCas9	negative selection	155393
40844895	40844918	15	-	26472758	Jiyoye	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-0.8360957695064903	[231]	[97]	-5	hSpCas9	negative selection	155394
40844718	40844741	15	-	26472758	Jiyoye	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	-0.06230990179534701	[35]	[25]	0	hSpCas9	negative selection	155395
40844858	40844881	15	+	26472758	Jiyoye	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	0.16866329480614856	[104]	[88]	1	hSpCas9	negative selection	155396
40853488	40853511	15	+	26472758	Jiyoye	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	4.99213788222703	[4]	[119]	9	hSpCas9	negative selection	155397
40853510	40853533	15	+	26472758	Jiyoye	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	3.214530303563477	[0]	[6]	9	hSpCas9	negative selection	155398
40853557	40853580	15	+	26472758	Jiyoye	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.40717538150587346	[76]	[76]	3	hSpCas9	negative selection	155399
40853838	40853861	15	-	26472758	Jiyoye	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	0.031963862720217895	[130]	[100]	0	hSpCas9	negative selection	155400
40855925	40855948	15	+	26472758	Jiyoye	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-1.5783250487990115	[98]	[24]	-7	hSpCas9	negative selection	155401
40844610	40844633	15	-	26472758	KBM7	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	-0.12925055755759385	[322,289]	[99,159]	-1	hSpCas9	negative selection	346510
40855938	40855961	15	-	26472758	KBM7	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	-0.24178570144672262	[169,209]	[128,29]	-2	hSpCas9	negative selection	346511
40844895	40844918	15	-	26472758	KBM7	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-1.370051538679068	[1048,760]	[176,149]	-7	hSpCas9	negative selection	346512
40844718	40844741	15	-	26472758	KBM7	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	-0.8388343148730932	[115,72]	[35,13]	-6	hSpCas9	negative selection	346513
40844858	40844881	15	+	26472758	KBM7	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	-0.03347010829258759	[524,328]	[229,158]	0	hSpCas9	negative selection	346514
40853488	40853511	15	+	26472758	KBM7	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-0.33735332031761467	[295,120]	[71,76]	-3	hSpCas9	negative selection	346515
40853510	40853533	15	+	26472758	KBM7	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	-0.6158785390377486	[177,208]	[47,70]	-5	hSpCas9	negative selection	346516
40853557	40853580	15	+	26472758	KBM7	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.5701350760616977	[426,281]	[186,293]	6	hSpCas9	negative selection	346517
40853838	40853861	15	-	26472758	KBM7	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.22324447179271578	[971,941]	[561,229]	-2	hSpCas9	negative selection	346518
40855925	40855948	15	+	26472758	KBM7	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	0.4493153176341106	[261,159]	[155,111]	5	hSpCas9	negative selection	346519
40844610	40844633	15	-	26472758	Raji	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	0.536634893872144	[100]	[33]	5	hSpCas9	negative selection	537628
40855938	40855961	15	-	26472758	Raji	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	0.21841484776234332	[99]	[26]	2	hSpCas9	negative selection	537629
40844895	40844918	15	-	26472758	Raji	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-1.0159988801316826	[365]	[41]	-6	hSpCas9	negative selection	537630
40844718	40844741	15	-	26472758	Raji	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	0.6126188436240216	[30]	[10]	6	hSpCas9	negative selection	537631
40844858	40844881	15	+	26472758	Raji	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	0.14055039930879876	[128]	[32]	1	hSpCas9	negative selection	537632
40853488	40853511	15	+	26472758	Raji	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-0.44956458917796016	[152]	[25]	-4	hSpCas9	negative selection	537633
40853510	40853533	15	+	26472758	Raji	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	2.1562931358545456	[28]	[29]	9	hSpCas9	negative selection	537634
40853557	40853580	15	+	26472758	Raji	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.17297187700117628	[171]	[44]	1	hSpCas9	negative selection	537635
40853838	40853861	15	-	26472758	Raji	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	0.22286075279353568	[431]	[116]	2	hSpCas9	negative selection	537636
40855925	40855948	15	+	26472758	Raji	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-0.6205369191895997	[105]	[15]	-5	hSpCas9	negative selection	537637
40844610	40844633	15	-	26472758	K562	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	-0.8216704627913254	[334]	[159]	-5	hSpCas9	negative selection	728746
40855938	40855961	15	-	26472758	K562	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	0.8987745638052773	[114]	[180]	7	hSpCas9	negative selection	728747
40844895	40844918	15	-	26472758	K562	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-3.26476592616795	[648]	[56]	-8	hSpCas9	negative selection	728748
40844718	40844741	15	-	26472758	K562	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	0.6377611558459715	[66]	[87]	5	hSpCas9	negative selection	728749
40844858	40844881	15	+	26472758	K562	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	-1.3941817366567828	[273]	[87]	-6	hSpCas9	negative selection	728750
40853488	40853511	15	+	26472758	K562	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-0.15893696656476153	[163]	[123]	-1	hSpCas9	negative selection	728751
40853510	40853533	15	+	26472758	K562	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	-1.8240610102163197	[150]	[35]	-7	hSpCas9	negative selection	728752
40853557	40853580	15	+	26472758	K562	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.37139158392421223	[249]	[272]	3	hSpCas9	negative selection	728753
40853838	40853861	15	-	26472758	K562	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.9231812208296217	[619]	[275]	-5	hSpCas9	negative selection	728754
40855925	40855948	15	+	26472758	K562	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-0.2359102318641162	[112]	[80]	-2	hSpCas9	negative selection	728755
40844747	40844770	15	+	26627737	DLD1	viability	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	-0.3848239337151661	[452]	[37,224,72]	-4	hSpCas9	negative selection	790473
40853142	40853165	15	-	26627737	DLD1	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-0.7942047487001713	[183]	[0,60,37]	-6	hSpCas9	negative selection	790474
40853606	40853629	15	+	26627737	DLD1	viability	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	0.3485422665854454	[411]	[252,135,109]	3	hSpCas9	negative selection	790475
40853745	40853768	15	-	26627737	DLD1	viability	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-1.0980495373109773	[455]	[149,43,12]	-7	hSpCas9	negative selection	790476
40854068	40854091	15	+	26627737	DLD1	viability	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	-0.7093772499545477	[209]	[55,65,4]	-6	hSpCas9	negative selection	790477
40854626	40854649	15	+	26627737	DLD1	viability	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	0.20576238410623146	[487]	[138,199,187]	2	hSpCas9	negative selection	790478
40844747	40844770	15	+	26627737	GBM cells	viability after 5 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	-1.0120349372971864	[266]	[99,41]	-9	hSpCas9	negative selection	872788
40853142	40853165	15	-	26627737	GBM cells	viability after 5 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.3495752838952506	[29]	[18,21]	5	hSpCas9	negative selection	872789
40853606	40853629	15	+	26627737	GBM cells	viability after 5 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	0.3067198049334536	[299]	[184,212]	5	hSpCas9	negative selection	872790
40853745	40853768	15	-	26627737	GBM cells	viability after 5 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-0.46148836781631264	[94]	[45,27]	-6	hSpCas9	negative selection	872791
40854068	40854091	15	+	26627737	GBM cells	viability after 5 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	-0.7724633776529437	[128]	[51,28]	-8	hSpCas9	negative selection	872792
40854626	40854649	15	+	26627737	GBM cells	viability after 5 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.43607037282712313	[221]	[86,88]	-6	hSpCas9	negative selection	872793
40844747	40844770	15	+	26627737	GBM cells	viability after 13 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	-1.1601471407882884	[266]	[55,71]	-8	hSpCas9	negative selection	955103
40853142	40853165	15	-	26627737	GBM cells	viability after 13 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-0.18225225067138418	[29]	[15,12]	-2	hSpCas9	negative selection	955104
40853606	40853629	15	+	26627737	GBM cells	viability after 13 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	0.20085946301547875	[299]	[153,213]	2	hSpCas9	negative selection	955105
40853745	40853768	15	-	26627737	GBM cells	viability after 13 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-1.557257628138726	[94]	[11,21]	-9	hSpCas9	negative selection	955106
40854068	40854091	15	+	26627737	GBM cells	viability after 13 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	-0.8283005533324992	[128]	[50,29]	-7	hSpCas9	negative selection	955107
40854626	40854649	15	+	26627737	GBM cells	viability after 13 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.14403109970126943	[221]	[124,95]	-2	hSpCas9	negative selection	955108
40844747	40844770	15	+	26627737	GBM cells	viability after 21 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	-0.4383965198145929	[266]	[105,107]	-4	hSpCas9	negative selection	1037418
40853142	40853165	15	-	26627737	GBM cells	viability after 21 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-1.7176104924022302	[29]	[5,3]	-8	hSpCas9	negative selection	1037419
40853606	40853629	15	+	26627737	GBM cells	viability after 21 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	0.2983932567073267	[299]	[201,198]	3	hSpCas9	negative selection	1037420
40853745	40853768	15	-	26627737	GBM cells	viability after 21 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-1.0683844216025833	[94]	[21,26]	-7	hSpCas9	negative selection	1037421
40854068	40854091	15	+	26627737	GBM cells	viability after 21 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	-0.565870715959051	[128]	[50,43]	-5	hSpCas9	negative selection	1037422
40854626	40854649	15	+	26627737	GBM cells	viability after 21 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	0.21544390814355133	[221]	[150,129]	2	hSpCas9	negative selection	1037423
40844747	40844770	15	+	26627737	RPE1	viability after 9 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	-0.35642815507685827	[786]	[229,143]	-3	hSpCas9	negative selection	1119733
40853142	40853165	15	-	26627737	RPE1	viability after 9 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	4.827195605792687	[0]	[14,0]	9	hSpCas9	negative selection	1119734
40853606	40853629	15	+	26627737	RPE1	viability after 9 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	-0.9950419882297052	[2029]	[217,448]	-6	hSpCas9	negative selection	1119735
40853745	40853768	15	-	26627737	RPE1	viability after 9 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	1.5355525773770533	[113]	[54,165]	8	hSpCas9	negative selection	1119736
40854068	40854091	15	+	26627737	RPE1	viability after 9 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	2.69506770954792	[53]	[67,162]	9	hSpCas9	negative selection	1119737
40854626	40854649	15	+	26627737	RPE1	viability after 9 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-1.402122149252851	[920]	[126,85]	-7	hSpCas9	negative selection	1119738
40844747	40844770	15	+	26627737	RPE1	viability after 12 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	-0.2949707175106506	[786]	[98,249]	-2	hSpCas9	negative selection	1202048
40853142	40853165	15	-	26627737	RPE1	viability after 12 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	5.1022187494220965	[0]	[16,0]	9	hSpCas9	negative selection	1202049
40853606	40853629	15	+	26627737	RPE1	viability after 12 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	-0.9976407144762562	[2029]	[175,375]	-6	hSpCas9	negative selection	1202050
40853745	40853768	15	-	26627737	RPE1	viability after 12 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-1.7262116165519457	[113]	[0,17]	-8	hSpCas9	negative selection	1202051
40854068	40854091	15	+	26627737	RPE1	viability after 12 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	3.018617607873691	[53]	[85,150]	9	hSpCas9	negative selection	1202052
40854626	40854649	15	+	26627737	RPE1	viability after 12 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.6959848291200859	[920]	[194,107]	-5	hSpCas9	negative selection	1202053
40844747	40844770	15	+	26627737	RPE1	viability after 15 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	-0.6137077785836735	[786]	[117,171]	-4	hSpCas9	negative selection	1284363
40853142	40853165	15	-	26627737	RPE1	viability after 15 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	7.246266702358783	[0]	[73,12]	9	hSpCas9	negative selection	1284364
40853606	40853629	15	+	26627737	RPE1	viability after 15 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	-0.9455253710088816	[2029]	[372,225]	-5	hSpCas9	negative selection	1284365
40853745	40853768	15	-	26627737	RPE1	viability after 15 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	0.6968737693696174	[113]	[64,39]	4	hSpCas9	negative selection	1284366
40854068	40854091	15	+	26627737	RPE1	viability after 15 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	2.9441559167281186	[53]	[113,120]	9	hSpCas9	negative selection	1284367
40854626	40854649	15	+	26627737	RPE1	viability after 15 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-1.028857350875959	[920]	[60,191]	-6	hSpCas9	negative selection	1284368
40844747	40844770	15	+	26627737	RPE1	viability after 18 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.12560103078157056	[786]	[193,271]	0	hSpCas9	negative selection	1366678
40853142	40853165	15	-	26627737	RPE1	viability after 18 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	4.837454055659805	[0]	[13,0]	9	hSpCas9	negative selection	1366679
40853606	40853629	15	+	26627737	RPE1	viability after 18 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	-1.5295405869556253	[2029]	[109,274]	-7	hSpCas9	negative selection	1366680
40853745	40853768	15	-	26627737	RPE1	viability after 18 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	0.7135673865684717	[113]	[48,51]	4	hSpCas9	negative selection	1366681
40854068	40854091	15	+	26627737	RPE1	viability after 18 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	3.0707766741184788	[53]	[47,201]	9	hSpCas9	negative selection	1366682
40854626	40854649	15	+	26627737	RPE1	viability after 18 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.8441653732400232	[920]	[136,139]	-5	hSpCas9	negative selection	1366683
40844747	40844770	15	+	26627737	HeLa	viability after 8 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.11921022275476506	[321]	[204,226,43]	1	hSpCas9	negative selection	1448993
40853142	40853165	15	-	26627737	HeLa	viability after 8 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	1.634071009003188	[0]	[0,1,0]	9	hSpCas9	negative selection	1448994
40853606	40853629	15	+	26627737	HeLa	viability after 8 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	-0.5212381948698884	[866]	[292,235,265]	-5	hSpCas9	negative selection	1448995
40853745	40853768	15	-	26627737	HeLa	viability after 8 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-0.6018257999402987	[168]	[11,56,66]	-5	hSpCas9	negative selection	1448996
40854068	40854091	15	+	26627737	HeLa	viability after 8 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	0.9956112894660119	[76]	[72,79,49]	7	hSpCas9	negative selection	1448997
40854626	40854649	15	+	26627737	HeLa	viability after 8 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.7034843025538952	[254]	[34,106,55]	-6	hSpCas9	negative selection	1448998
40844747	40844770	15	+	26627737	HeLa	viability after 12 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.5569237567799208	[321]	[313,230,41]	4	hSpCas9	negative selection	1531308
40853142	40853165	15	-	26627737	HeLa	viability after 12 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	5.315213047874099	[0]	[41,7,0]	9	hSpCas9	negative selection	1531309
40853606	40853629	15	+	26627737	HeLa	viability after 12 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	-1.2475002713399717	[866]	[118,148,183]	-8	hSpCas9	negative selection	1531310
40853745	40853768	15	-	26627737	HeLa	viability after 12 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-0.1592502064003527	[168]	[135,31,24]	-1	hSpCas9	negative selection	1531311
40854068	40854091	15	+	26627737	HeLa	viability after 12 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	1.4264488191677214	[76]	[118,71,67]	8	hSpCas9	negative selection	1531312
40854626	40854649	15	+	26627737	HeLa	viability after 12 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.37804858322935064	[254]	[68,51,124]	-3	hSpCas9	negative selection	1531313
40844747	40844770	15	+	26627737	HeLa	viability after 15 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.14174369547859003	[321]	[250,78,98]	1	hSpCas9	negative selection	1613623
40853142	40853165	15	-	26627737	HeLa	viability after 15 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	6.773377512503386	[0]	[88,23,17]	9	hSpCas9	negative selection	1613624
40853606	40853629	15	+	26627737	HeLa	viability after 15 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	-0.49881535022914936	[866]	[251,178,323]	-4	hSpCas9	negative selection	1613625
40853745	40853768	15	-	26627737	HeLa	viability after 15 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	0.10720565219954548	[168]	[139,0,80]	0	hSpCas9	negative selection	1613626
40854068	40854091	15	+	26627737	HeLa	viability after 15 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	1.7395600915705214	[76]	[224,48,32]	9	hSpCas9	negative selection	1613627
40854626	40854649	15	+	26627737	HeLa	viability after 15 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	0.5426666379098902	[254]	[77,135,247]	4	hSpCas9	negative selection	1613628
40844747	40844770	15	+	26627737	HeLa	viability after 18 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.1410044190251638	[321]	[166,66,98]	1	hSpCas9	negative selection	1695938
40853142	40853165	15	-	26627737	HeLa	viability after 18 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	6.831893286124576	[0]	[59,23,17]	9	hSpCas9	negative selection	1695939
40853606	40853629	15	+	26627737	HeLa	viability after 18 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	-0.5001733179915617	[866]	[171,143,323]	-4	hSpCas9	negative selection	1695940
40853745	40853768	15	-	26627737	HeLa	viability after 18 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	0.05836980630183519	[168]	[88,0,80]	0	hSpCas9	negative selection	1695941
40854068	40854091	15	+	26627737	HeLa	viability after 18 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	1.7660533050389609	[76]	[151,43,32]	9	hSpCas9	negative selection	1695942
40854626	40854649	15	+	26627737	HeLa	viability after 18 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	0.5454858020343814	[254]	[54,109,247]	4	hSpCas9	negative selection	1695943
40844747	40844770	15	+	26627737	HCT116	viability after 6 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	-0.45142656114085805	[773]	[39,115]	-3	hSpCas9	negative selection	1778253
40853142	40853165	15	-	26627737	HCT116	viability after 6 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	6.446760997250641	[1]	[0,41]	9	hSpCas9	negative selection	1778254
40853606	40853629	15	+	26627737	HCT116	viability after 6 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	-0.5983402686360619	[730]	[111,55]	-3	hSpCas9	negative selection	1778255
40853745	40853768	15	-	26627737	HCT116	viability after 6 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-0.030221154921308384	[591]	[201,29]	0	hSpCas9	negative selection	1778256
40854068	40854091	15	+	26627737	HCT116	viability after 6 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	1.0090550151933195	[190]	[140,15]	5	hSpCas9	negative selection	1778257
40854626	40854649	15	+	26627737	HCT116	viability after 6 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	0.0997759089670946	[510]	[107,73]	0	hSpCas9	negative selection	1778258
40844747	40844770	15	+	26627737	HCT116	viability after 8 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.5977358997324935	[152]	[144,104,132]	6	hSpCas9	negative selection	1860568
40853142	40853165	15	-	26627737	HCT116	viability after 8 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-0.2164927321718224	[75]	[21,59,25]	-2	hSpCas9	negative selection	1860569
40853606	40853629	15	+	26627737	HCT116	viability after 8 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	0.7568490117483451	[335]	[258,232,443]	7	hSpCas9	negative selection	1860570
40853745	40853768	15	-	26627737	HCT116	viability after 8 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-0.7908963369204407	[280]	[57,126,82]	-7	hSpCas9	negative selection	1860571
40854068	40854091	15	+	26627737	HCT116	viability after 8 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	-0.08991172494722832	[101]	[26,80,49]	-1	hSpCas9	negative selection	1860572
40854626	40854649	15	+	26627737	HCT116	viability after 8 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.5856411215146221	[332]	[165,112,88]	-6	hSpCas9	negative selection	1860573
40844747	40844770	15	+	26627737	HCT116	viability after 9 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.30284764194150277	[773]	[450,99]	2	hSpCas9	negative selection	1942883
40853142	40853165	15	-	26627737	HCT116	viability after 9 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	6.337889044908856	[1]	[88,6]	9	hSpCas9	negative selection	1942884
40853606	40853629	15	+	26627737	HCT116	viability after 9 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	0.08506308204689583	[730]	[363,82]	0	hSpCas9	negative selection	1942885
40853745	40853768	15	-	26627737	HCT116	viability after 9 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-1.2089952503227586	[591]	[121,25]	-7	hSpCas9	negative selection	1942886
40854068	40854091	15	+	26627737	HCT116	viability after 9 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	1.047489328324954	[190]	[110,100]	7	hSpCas9	negative selection	1942887
40854626	40854649	15	+	26627737	HCT116	viability after 9 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.63467937843787	[510]	[26,135]	-4	hSpCas9	negative selection	1942888
40844747	40844770	15	+	26627737	HCT116	viability after 12 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.2794316222319604	[152]	[96,104,90]	3	hSpCas9	negative selection	2025198
40853142	40853165	15	-	26627737	HCT116	viability after 12 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-0.5564964608276646	[75]	[27,51,1]	-5	hSpCas9	negative selection	2025199
40853606	40853629	15	+	26627737	HCT116	viability after 12 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	0.5572813919905598	[335]	[269,234,272]	5	hSpCas9	negative selection	2025200
40853745	40853768	15	-	26627737	HCT116	viability after 12 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-0.28753537274468066	[280]	[94,151,118]	-3	hSpCas9	negative selection	2025201
40854068	40854091	15	+	26627737	HCT116	viability after 12 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	-0.5415600800231082	[101]	[13,57,40]	-5	hSpCas9	negative selection	2025202
40854626	40854649	15	+	26627737	HCT116	viability after 12 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-1.1187617951309181	[332]	[71,141,29]	-8	hSpCas9	negative selection	2025203
40844747	40844770	15	+	26627737	HCT116	viability after 15 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	1.112794931735375	[152]	[139,151,270]	8	hSpCas9	negative selection	2107513
40853142	40853165	15	-	26627737	HCT116	viability after 15 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-1.4538094861989825	[75]	[25,4,17]	-8	hSpCas9	negative selection	2107514
40853606	40853629	15	+	26627737	HCT116	viability after 15 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	0.7549173150570103	[335]	[407,342,236]	6	hSpCas9	negative selection	2107515
40853745	40853768	15	-	26627737	HCT116	viability after 15 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-0.41190767493729874	[280]	[27,241,82]	-4	hSpCas9	negative selection	2107516
40854068	40854091	15	+	26627737	HCT116	viability after 15 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	0.653586160164122	[101]	[43,85,139]	6	hSpCas9	negative selection	2107517
40854626	40854649	15	+	26627737	HCT116	viability after 15 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.7260554119456468	[332]	[246,96,19]	-6	hSpCas9	negative selection	2107518
40844747	40844770	15	+	26627737	HCT116	viability after 18 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	1.1196631114442797	[152]	[81,168,233]	8	hSpCas9	negative selection	2189828
40853142	40853165	15	-	26627737	HCT116	viability after 18 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-0.3034437252048763	[75]	[30,31,25]	-3	hSpCas9	negative selection	2189829
40853606	40853629	15	+	26627737	HCT116	viability after 18 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	1.5189780853376962	[335]	[363,734,270]	9	hSpCas9	negative selection	2189830
40853745	40853768	15	-	26627737	HCT116	viability after 18 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-0.20196616122993113	[280]	[64,270,2]	-2	hSpCas9	negative selection	2189831
40854068	40854091	15	+	26627737	HCT116	viability after 18 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	-1.4569848985020704	[101]	[11,27,12]	-8	hSpCas9	negative selection	2189832
40854626	40854649	15	+	26627737	HCT116	viability after 18 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.21234573182254443	[332]	[222,128,61]	-2	hSpCas9	negative selection	2189833
40844357	40844380	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGTGCGCCCTCTTCGATCCTGG	SPINT1	ENSG00000166145	1.4330159001638403	[41,134]	[3,105]	5	dCas9-VP64	positive selection	2390844
40844275	40844298	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCTAGGGAGCTCAAGTACCCGG	SPINT1	ENSG00000166145	-0.35662697240803987	[74,25]	[4,10]	-2	dCas9-VP64	positive selection	2390845
40844257	40844280	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCGCTCGTGCGTGTGTCCGGG	SPINT1	ENSG00000166145	-1.5284472511955876	[29,43]	[2,0]	-8	dCas9-VP64	positive selection	2390846
40844357	40844380	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGTGCGCCCTCTTCGATCCTGG	SPINT1	ENSG00000166145	0.11238051693177441	[174,55]	[60,21]	0	dCas9-VP64	positive selection	2486099
40844275	40844298	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCTAGGGAGCTCAAGTACCCGG	SPINT1	ENSG00000166145	-1.1325510797752247	[12,261]	[5,31]	-9	dCas9-VP64	positive selection	2486100
40844257	40844280	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCGCTCGTGCGTGTGTCCGGG	SPINT1	ENSG00000166145	0.17918900488017742	[53,9]	[15,7]	1	dCas9-VP64	positive selection	2486101
40844963	40844986	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCATCAACTACCTCACGAGGG	SPINT1	ENSG00000166145	-0.21188776592975542	[4,4]	[5,1]	-3	hSpCas9	positive selection	3023416
40844784	40844807	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTCCCCCACCGTGCGCCGGGG	SPINT1	ENSG00000166145	-0.7549470088370605	[2,2]	[2,0]	-8	hSpCas9	positive selection	3023417
40844610	40844633	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	-1.223722972694248	[3,2]	[0,0]	-9	hSpCas9	positive selection	3023418
40844895	40844918	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	0.4309712450755286	[5,5]	[6,6]	8	hSpCas9	positive selection	3023419
40844963	40844986	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCATCAACTACCTCACGAGGG	SPINT1	ENSG00000166145	0.31556743762266376	[4,4]	[6,3]	5	hSpCas9	positive selection	3091274
40844784	40844807	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTCCCCCACCGTGCGCCGGGG	SPINT1	ENSG00000166145	-0.14981770965862296	[2,2]	[2,0]	-2	hSpCas9	positive selection	3091275
40844610	40844633	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	0.6175011343879677	[3,3]	[4,3]	8	hSpCas9	positive selection	3091276
40844895	40844918	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	0.454566473016811	[5,5]	[6,4]	7	hSpCas9	positive selection	3091277
40853218	40853241		-	24336571	A375	resistance to PLX after 7 days	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	0.06998457484126042	[27,25]	[26,28]	2	hSpCas9	positive selection	3147164
40853545	40853568		-	24336571	A375	resistance to PLX after 7 days	CTGAGCTAGTCACTGTCAGCTGG	SPINT1	ENSG00000166145	0.010167060798790817	[22,19]	[20,21]	0	hSpCas9	positive selection	3147165
40853230	40853253		+	24336571	A375	resistance to PLX after 7 days	TGACACGGATGTCAGGGTAGAGG	SPINT1	ENSG00000166145	-0.15521217184511216	[9,14]	[11,9]	-5	hSpCas9	positive selection	3147166
40853503	40853526		-	24336571	A375	resistance to PLX after 7 days	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.15564434378276681	[38,44]	[49,42]	5	hSpCas9	positive selection	3147167
40853218	40853241		-	24336571	A375	resistance to PLX after 14 days	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.46141260870735934	[24,26]	[8,7]	-5	hSpCas9	positive selection	3204957
40853545	40853568		-	24336571	A375	resistance to PLX after 14 days	CTGAGCTAGTCACTGTCAGCTGG	SPINT1	ENSG00000166145	0.19388096103433738	[19,17]	[12,6]	2	hSpCas9	positive selection	3204958
40853230	40853253		+	24336571	A375	resistance to PLX after 14 days	TGACACGGATGTCAGGGTAGAGG	SPINT1	ENSG00000166145	0.249332273486579	[7,8]	[2,4]	2	hSpCas9	positive selection	3204959
40853503	40853526		-	24336571	A375	resistance to PLX after 14 days	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.19625608835942376	[40,44]	[19,25]	2	hSpCas9	positive selection	3204960
40853218	40853241		-	24336571	A375	viability after 7 days	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.5126465689266586	[40]	[27,25]	-6	hSpCas9	negative selection	3262750
40853545	40853568		-	24336571	A375	viability after 7 days	CTGAGCTAGTCACTGTCAGCTGG	SPINT1	ENSG00000166145	0.11886001297738746	[19]	[22,19]	1	hSpCas9	negative selection	3262751
40853230	40853253		+	24336571	A375	viability after 7 days	TGACACGGATGTCAGGGTAGAGG	SPINT1	ENSG00000166145	0.40922341263725837	[9]	[9,14]	6	hSpCas9	negative selection	3262752
40853503	40853526		-	24336571	A375	viability after 7 days	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.036070799384173347	[44]	[38,44]	0	hSpCas9	negative selection	3262753
40853218	40853241		-	24336571	A375	viability after 14 days	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.5319366246282737	[40]	[24,26]	-6	hSpCas9	negative selection	3320543
40853545	40853568		-	24336571	A375	viability after 14 days	CTGAGCTAGTCACTGTCAGCTGG	SPINT1	ENSG00000166145	-0.006481780177851615	[19]	[19,17]	0	hSpCas9	negative selection	3320544
40853230	40853253		+	24336571	A375	viability after 14 days	TGACACGGATGTCAGGGTAGAGG	SPINT1	ENSG00000166145	-0.11112939856653076	[9]	[7,8]	-1	hSpCas9	negative selection	3320545
40853503	40853526		-	24336571	A375	viability after 14 days	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.014163635478029457	[44]	[40,44]	0	hSpCas9	negative selection	3320546
40853557	40853580	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.5240335020788246	[219,219]	[0,0]	-3	hSpCas9	positive selection	3394721
40853503	40853526	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-1.8433361275593636	[548,548]	[0,0]	-9	hSpCas9	positive selection	3394722
40854049	40854072	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	1.529405756882636	[52,52]	[0,0]	6	hSpCas9	positive selection	3394723
40844962	40844985	15	+	26780180	HT29	viability (Avana library 4 designs)	CTTCATCAACTACCTCACGAGGG	SPINT1	ENSG00000166145	0.512894286160376	[]	[]	2	hSpCas9	negative selection	3462040
40844783	40844806	15	+	26780180	HT29	viability (Avana library 4 designs)	GAGTCCCCCACCGTGCGCCGGGG	SPINT1	ENSG00000166145	0.130742179730351	[]	[]	0	hSpCas9	negative selection	3462041
40844610	40844633	15	-	26780180	HT29	viability (Avana library 4 designs)	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	1.55906077003535	[]	[]	6	hSpCas9	negative selection	3462042
40844895	40844918	15	-	26780180	HT29	viability (Avana library 4 designs)	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	1.00252066334453	[]	[]	4	hSpCas9	negative selection	3462043
40844962	40844985	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCATCAACTACCTCACGAGGG	SPINT1	ENSG00000166145	-6.57419714413339	[]	[]	-6	hSpCas9	negative selection	3563380
40844610	40844633	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	4.85163675881796	[]	[]	8	hSpCas9	negative selection	3563381
40844895	40844918	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	4.66423609700001	[]	[]	7	hSpCas9	negative selection	3563382
40844783	40844806	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTCCCCCACCGTGCGCCGGGG	SPINT1	ENSG00000166145	2.24554137002774	[]	[]	3	hSpCas9	negative selection	3563383
40853557	40853580	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	2.39111618917925	[]	[]	3	hSpCas9	negative selection	3563384
40844704	40844727	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.016767513239238	[]	[]	0	hSpCas9	negative selection	3563385
40844962	40844985	15	+	26780180	A375	viability (Avana lentiGuide)	CTTCATCAACTACCTCACGAGGG	SPINT1	ENSG00000166145	7.60451567181872	[]	[]	6	hSpCas9	negative selection	3672039
40844610	40844633	15	-	26780180	A375	viability (Avana lentiGuide)	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	5.05091410341219	[]	[]	4	hSpCas9	negative selection	3672040
40844895	40844918	15	-	26780180	A375	viability (Avana lentiGuide)	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	0.329349756064411	[]	[]	0	hSpCas9	negative selection	3672041
40844783	40844806	15	+	26780180	A375	viability (Avana lentiGuide)	GAGTCCCCCACCGTGCGCCGGGG	SPINT1	ENSG00000166145	-1.01828418964659	[]	[]	-1	hSpCas9	negative selection	3672042
40853557	40853580	15	+	26780180	A375	viability (Avana lentiGuide)	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	7.84710884929138	[]	[]	6	hSpCas9	negative selection	3672043
40844704	40844727	15	+	26780180	A375	viability (Avana lentiGuide)	CCTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	-1.85184948433364	[]	[]	-3	hSpCas9	negative selection	3672044
40844962	40844985	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCATCAACTACCTCACGAGGG	SPINT1	ENSG00000166145	-0.9791148111881102	[6]	[3,1]	-8	hSpCas9	positive selection	3780646
40844610	40844633	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	0.31907624818701624	[4]	[4,5]	8	hSpCas9	positive selection	3780647
40844895	40844918	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	0.19050240581238348	[5]	[6,6]	5	hSpCas9	positive selection	3780648
40844783	40844806	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTCCCCCACCGTGCGCCGGGG	SPINT1	ENSG00000166145	0.1949677253353585	[4]	[5,4]	5	hSpCas9	positive selection	3780649
40853557	40853580	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.2643069918509986	[3]	[5,4]	7	hSpCas9	positive selection	3780650
40844704	40844727	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.04994748436359481	[4]	[4,4]	1	hSpCas9	positive selection	3780651
40844962	40844985	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCATCAACTACCTCACGAGGG	SPINT1	ENSG00000166145	-0.03359843076442748	[6]	[4,6]	0	hSpCas9	positive selection	3889253
40844610	40844633	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	-0.6448932717345349	[4]	[0,3]	-7	hSpCas9	positive selection	3889254
40844895	40844918	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	0.12922603481087752	[7]	[6,6]	3	hSpCas9	positive selection	3889255
40844783	40844806	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTCCCCCACCGTGCGCCGGGG	SPINT1	ENSG00000166145	0.015495525524271858	[4]	[3,4]	0	hSpCas9	positive selection	3889256
40853557	40853580	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.18057549758169966	[4]	[4,4]	4	hSpCas9	positive selection	3889257
40844704	40844727	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.2997556097665786	[4]	[5,4]	8	hSpCas9	positive selection	3889258
40854066	40854089	15	-	26780180	A375	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	1.0139638563727	[]	[]	5	hSpCas9	negative selection	3999005
40853218	40853241	15	-	26780180	A375	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	1.26890562699853	[]	[]	7	hSpCas9	negative selection	3999006
40854049	40854072	15	+	26780180	A375	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.678822664351348	[]	[]	2	hSpCas9	negative selection	3999007
40853142	40853165	15	-	26780180	A375	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	1.04312886385613	[]	[]	5	hSpCas9	negative selection	3999008
40853557	40853580	15	+	26780180	A375	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	1.21688575676418	[]	[]	6	hSpCas9	negative selection	3999009
40853503	40853526	15	-	26780180	A375	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	1.36415243221046	[]	[]	7	hSpCas9	negative selection	3999010
40854066	40854089	15	-	26780180	HT29	viability (GeCKOv2 library)	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.365061018118343	[]	[]	1	hSpCas9	negative selection	4106971
40853218	40853241	15	-	26780180	HT29	viability (GeCKOv2 library)	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	1.06467511641059	[]	[]	5	hSpCas9	negative selection	4106972
40854049	40854072	15	+	26780180	HT29	viability (GeCKOv2 library)	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.684144145675954	[]	[]	2	hSpCas9	negative selection	4106973
40853142	40853165	15	-	26780180	HT29	viability (GeCKOv2 library)	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	1.50580523915903	[]	[]	7	hSpCas9	negative selection	4106974
40853557	40853580	15	+	26780180	HT29	viability (GeCKOv2 library)	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	1.6554945899024	[]	[]	8	hSpCas9	negative selection	4106975
40853503	40853526	15	-	26780180	HT29	viability (GeCKOv2 library)	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	1.00611770737383	[]	[]	4	hSpCas9	negative selection	4106976
40853218	40853241	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	0.0481051263242831	[4]	[3,3]	1	hSpCas9	positive selection	4173331
40853545	40853568	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGAGCTAGTCACTGTCAGCTGG	SPINT1	ENSG00000166145	0.022556110359701925	[4]	[2,3]	0	hSpCas9	positive selection	4173332
40853230	40853253	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGACACGGATGTCAGGGTAGAGG	SPINT1	ENSG00000166145	0.333834038567201	[2]	[2,1]	7	hSpCas9	positive selection	4173333
40853503	40853526	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.1629621984573929	[5]	[3,4]	4	hSpCas9	positive selection	4173334
40853218	40853241	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	0.022327191099033916	[4]	[2,3,2,0]	0	hSpCas9	positive selection	4237353
40853545	40853568	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGAGCTAGTCACTGTCAGCTGG	SPINT1	ENSG00000166145	0.3553009418953406	[4]	[3,3,4,0]	2	hSpCas9	positive selection	4237354
40853230	40853253	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGACACGGATGTCAGGGTAGAGG	SPINT1	ENSG00000166145	0.055372253465210325	[3]	[1,3,0,0]	0	hSpCas9	positive selection	4237355
40853503	40853526	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.08957536782023967	[5]	[4,3,1,0]	-1	hSpCas9	positive selection	4237356
40853218	40853241	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	0.21300824714466166	[4]	[2,4]	4	hSpCas9	positive selection	4300336
40853142	40853165	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-0.25920355041692505	[3]	[2,1]	-5	hSpCas9	positive selection	4300337
40854066	40854089	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.016243170677125718	[2]	[1,1]	0	hSpCas9	positive selection	4300338
40853557	40853580	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.31405251749049373	[3]	[3,2]	6	hSpCas9	positive selection	4364591
40853503	40853526	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.09799364334027422	[4]	[3,1]	-2	hSpCas9	positive selection	4364592
40854049	40854072	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.18055933183411943	[1]	[1,0]	-4	hSpCas9	positive selection	4364593
40844705	40844727	15	+	27760321	OCIAML3	viability	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.6788252589866443	[914,754]	[912,1206]	7	hSpCas9	negative selection	4442802
40844840	40844862	15	+	27760321	OCIAML3	viability	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	-0.32749517692869645	[1035,892]	[608,586]	-3	hSpCas9	negative selection	4442803
40844871	40844893	15	-	27760321	OCIAML3	viability	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-0.6123514593216189	[1109,1012]	[412,711]	-5	hSpCas9	negative selection	4442804
40844917	40844939	15	-	27760321	OCIAML3	viability	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	-0.7080198739950427	[641,532]	[286,270]	-6	hSpCas9	negative selection	4442805
40844939	40844961	15	+	27760321	OCIAML3	viability	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	-0.018226591780723833	[949,735]	[526,801]	0	hSpCas9	negative selection	4442806
40844705	40844727	15	+	27760321	OCIAML2	viability	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.31925153333322587	[914,754]	[661,1071]	4	hSpCas9	negative selection	4526265
40844840	40844862	15	+	27760321	OCIAML2	viability	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	-0.026361832114762063	[1035,892]	[684,867]	0	hSpCas9	negative selection	4526266
40844871	40844893	15	-	27760321	OCIAML2	viability	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-1.1932896463118043	[1109,1012]	[345,413]	-8	hSpCas9	negative selection	4526267
40844917	40844939	15	-	27760321	OCIAML2	viability	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	-0.021051085715977913	[641,532]	[414,533]	0	hSpCas9	negative selection	4526268
40844939	40844961	15	+	27760321	OCIAML2	viability	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	-0.4023502824922893	[949,735]	[384,679]	-5	hSpCas9	negative selection	4526269
40844705	40844727	15	+	27760321	MV411	viability	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.9794799747361925	[914,754]	[1194,910]	7	hSpCas9	negative selection	4609728
40844840	40844862	15	+	27760321	MV411	viability	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	0.6191894752715037	[1035,892]	[846,1166]	4	hSpCas9	negative selection	4609729
40844871	40844893	15	-	27760321	MV411	viability	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-1.6373835397942984	[1109,1012]	[53,481]	-8	hSpCas9	negative selection	4609730
40844917	40844939	15	-	27760321	MV411	viability	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	-0.375304636260041	[641,532]	[289,308]	-3	hSpCas9	negative selection	4609731
40844939	40844961	15	+	27760321	MV411	viability	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	0.6661747126230786	[949,735]	[714,1118]	5	hSpCas9	negative selection	4609732
40844705	40844727	15	+	27760321	HL60	viability	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.10634552085973448	[914,754]	[760,698]	1	hSpCas9	negative selection	4693191
40844840	40844862	15	+	27760321	HL60	viability	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	0.31564318873795183	[1035,892]	[1120,825]	4	hSpCas9	negative selection	4693192
40844871	40844893	15	-	27760321	HL60	viability	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-0.08948420691854286	[1109,1012]	[833,793]	-1	hSpCas9	negative selection	4693193
40844917	40844939	15	-	27760321	HL60	viability	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	0.010747461218545418	[641,532]	[378,589]	0	hSpCas9	negative selection	4693194
40844939	40844961	15	+	27760321	HL60	viability	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	-0.5859491535513908	[949,735]	[471,437]	-6	hSpCas9	negative selection	4693195
40844705	40844727	15	+	27760321	HT1080	viability	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.08555011579250205	[754,588]	[242,328]	0	hSpCas9	negative selection	4776654
40844840	40844862	15	+	27760321	HT1080	viability	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	-1.2692472938062243	[892,696]	[86,179]	-5	hSpCas9	negative selection	4776655
40844871	40844893	15	-	27760321	HT1080	viability	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-1.8643801824590835	[1012,790]	[49,151]	-6	hSpCas9	negative selection	4776656
40844917	40844939	15	-	27760321	HT1080	viability	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	-0.4692694161172456	[532,415]	[168,100]	-2	hSpCas9	negative selection	4776657
40844939	40844961	15	+	27760321	HT1080	viability	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	2.181174230991234	[735,574]	[1855,448]	9	hSpCas9	negative selection	4776658
40844705	40844727	15	+	27760321	HT29	viability after 7 days	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	-0.2082971949511052	[754,588]	[778,661,803]	-3	hSpCas9	negative selection	4860117
40844840	40844862	15	+	27760321	HT29	viability after 7 days	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	0.11451666520111003	[892,696]	[751,944,1555]	1	hSpCas9	negative selection	4860118
40844871	40844893	15	-	27760321	HT29	viability after 7 days	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-0.25931054649534935	[1012,790]	[1184,773,976]	-4	hSpCas9	negative selection	4860119
40844917	40844939	15	-	27760321	HT29	viability after 7 days	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	0.08262228832637247	[532,415]	[607,876,452]	1	hSpCas9	negative selection	4860120
40844939	40844961	15	+	27760321	HT29	viability after 7 days	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	0.025810145657421235	[735,574]	[1314,621,705]	0	hSpCas9	negative selection	4860121
40844705	40844727	15	+	27760321	HT29	viability after 25 days	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.2868158567151893	[754,588]	[711,849,1298]	3	hSpCas9	negative selection	4943580
40844840	40844862	15	+	27760321	HT29	viability after 25 days	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	0.03465652191358215	[892,696]	[853,823,1138]	0	hSpCas9	negative selection	4943581
40844871	40844893	15	-	27760321	HT29	viability after 25 days	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-0.7147115882731426	[1012,790]	[456,517,952]	-5	hSpCas9	negative selection	4943582
40844917	40844939	15	-	27760321	HT29	viability after 25 days	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	-0.0919733399423916	[532,415]	[411,607,511]	-1	hSpCas9	negative selection	4943583
40844939	40844961	15	+	27760321	HT29	viability after 25 days	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	0.3777568219882891	[735,574]	[849,874,1227]	4	hSpCas9	negative selection	4943584
40844705	40844727	15	+	27760321	HT29	viability after 22 days	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.31631142558617986	[754,588]	[889,1035,977]	3	hSpCas9	negative selection	5027043
40844840	40844862	15	+	27760321	HT29	viability after 22 days	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	0.0738840410084578	[892,696]	[1249,926,714]	0	hSpCas9	negative selection	5027044
40844871	40844893	15	-	27760321	HT29	viability after 22 days	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-0.8897034818140828	[1012,790]	[451,616,622]	-6	hSpCas9	negative selection	5027045
40844917	40844939	15	-	27760321	HT29	viability after 22 days	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	-0.058221302571754174	[532,415]	[381,721,479]	0	hSpCas9	negative selection	5027046
40844939	40844961	15	+	27760321	HT29	viability after 22 days	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	0.5762042396029065	[735,574]	[1056,948,1387]	6	hSpCas9	negative selection	5027047
40844705	40844727	15	+	27760321	HT29	viability after 19 days	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.3516082333913675	[754,588]	[783,1111,1022]	3	hSpCas9	negative selection	5110506
40844840	40844862	15	+	27760321	HT29	viability after 19 days	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	0.15705238981017589	[892,696]	[1385,983,720]	1	hSpCas9	negative selection	5110507
40844871	40844893	15	-	27760321	HT29	viability after 19 days	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-0.7149297921149063	[1012,790]	[388,466,989]	-5	hSpCas9	negative selection	5110508
40844917	40844939	15	-	27760321	HT29	viability after 19 days	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	-0.2734271922118545	[532,415]	[507,614,237]	-3	hSpCas9	negative selection	5110509
40844939	40844961	15	+	27760321	HT29	viability after 19 days	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	-0.022170866718175253	[735,574]	[1021,588,636]	0	hSpCas9	negative selection	5110510
40844705	40844727	15	+	27760321	HT29	viability after 16 days	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.3658046909091286	[754,588]	[971,758,1180]	4	hSpCas9	negative selection	5193969
40844840	40844862	15	+	27760321	HT29	viability after 16 days	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	0.11537631274945159	[892,696]	[1175,1056,674]	1	hSpCas9	negative selection	5193970
40844871	40844893	15	-	27760321	HT29	viability after 16 days	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-0.7098456235547632	[1012,790]	[909,524,445]	-6	hSpCas9	negative selection	5193971
40844917	40844939	15	-	27760321	HT29	viability after 16 days	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	-0.10388657705636944	[532,415]	[610,376,507]	-1	hSpCas9	negative selection	5193972
40844939	40844961	15	+	27760321	HT29	viability after 16 days	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	0.42446647009263605	[735,574]	[819,1031,1083]	5	hSpCas9	negative selection	5193973
40844705	40844727	15	+	27760321	HT29	viability after 13 days	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.0799683204358429	[754,588]	[563,820,1071]	1	hSpCas9	negative selection	5277432
40844840	40844862	15	+	27760321	HT29	viability after 13 days	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	0.06878769084449421	[892,696]	[1374,884,659]	0	hSpCas9	negative selection	5277433
40844871	40844893	15	-	27760321	HT29	viability after 13 days	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-0.7633387753412044	[1012,790]	[682,494,667]	-7	hSpCas9	negative selection	5277434
40844917	40844939	15	-	27760321	HT29	viability after 13 days	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	0.08182091086853371	[532,415]	[454,744,549]	1	hSpCas9	negative selection	5277435
40844939	40844961	15	+	27760321	HT29	viability after 13 days	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	0.3956120051274544	[735,574]	[1442,793,776]	5	hSpCas9	negative selection	5277436
40844705	40844727	15	+	27760321	HT29	viability after 10 days	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	0.5136941590200839	[754,588]	[852,883,1832]	7	hSpCas9	negative selection	5360895
40844840	40844862	15	+	27760321	HT29	viability after 10 days	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	0.2416971343538219	[892,696]	[1342,1383,807]	3	hSpCas9	negative selection	5360896
40844871	40844893	15	-	27760321	HT29	viability after 10 days	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-0.27583640441152046	[1012,790]	[661,938,1183]	-4	hSpCas9	negative selection	5360897
40844917	40844939	15	-	27760321	HT29	viability after 10 days	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	-0.34634414212988396	[532,415]	[400,636,366]	-4	hSpCas9	negative selection	5360898
40844939	40844961	15	+	27760321	HT29	viability after 10 days	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	0.23781668717053972	[735,574]	[1075,728,1080]	3	hSpCas9	negative selection	5360899
40844705	40844727	15	+	27760321	MOLM13	viability	CTGAACAGCTTTACCGCCGGGG	SPINT1	ENSG00000166145	-0.05775508781173233	[914,754]	[644,284]	0	hSpCas9	negative selection	5444358
40844840	40844862	15	+	27760321	MOLM13	viability	AACTGCAACTTGGCGCTAGTGG	SPINT1	ENSG00000166145	0.412613734921645	[1035,892]	[697,742]	3	hSpCas9	negative selection	5444359
40844871	40844893	15	-	27760321	MOLM13	viability	ATGGCGTCCTCCCCGCGGTCGG	SPINT1	ENSG00000166145	-1.3784164043613942	[1109,1012]	[125,318]	-7	hSpCas9	negative selection	5444360
40844917	40844939	15	-	27760321	MOLM13	viability	CACGAAGTTCTGCTCGTAGAGG	SPINT1	ENSG00000166145	-0.7154683643132279	[641,532]	[301,114]	-4	hSpCas9	negative selection	5444361
40844939	40844961	15	+	27760321	MOLM13	viability	TGCAAGTTCGCGCCCAGGGAGG	SPINT1	ENSG00000166145	0.10194763115315753	[949,735]	[643,389]	0	hSpCas9	negative selection	5444362
40844290	40844313	15	-	27661255	K562	viability	GACGGACAGGCGGACCGCTAGGG	SPINT1	ENSG00000166145	0.16469344639844974	[1238,1249]	[1233,1011]	6	dCas9-KRAB	negative selection	5513996
40844610	40844633	15	-	27661255	K562	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	0.03417707598410602	[283,365]	[289,242]	1	dCas9-KRAB	negative selection	5513997
40853218	40853241	15	-	27260156	BXPC3	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.16475575747348636	[1072]	[895,886,1025,1234]	-4	hSpCas9	negative selection	5572796
40853142	40853165	15	-	27260156	BXPC3	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.14478459504248997	[732]	[765,800,762,1093]	3	hSpCas9	negative selection	5572797
40854066	40854089	15	-	27260156	BXPC3	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.44606298942256095	[202]	[217,263,334,355]	8	hSpCas9	negative selection	5572798
40853557	40853580	15	+	27260156	BXPC3	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.028121342167318982	[463]	[499,327,597,482]	0	hSpCas9	negative selection	5637051
40853503	40853526	15	-	27260156	BXPC3	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.05209284278278359	[1042]	[962,999,1030,1241]	-1	hSpCas9	negative selection	5637052
40854049	40854072	15	+	27260156	BXPC3	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.23786744918330482	[93]	[78,66,204,120]	5	hSpCas9	negative selection	5637053
40853218	40853241	15	-	27260156	A673	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.15215547111058703	[1072]	[1326,1028,1102,1201]	-4	hSpCas9	negative selection	5694047
40853142	40853165	15	-	27260156	A673	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.28352058711380035	[732]	[1125,1143,1055,954]	6	hSpCas9	negative selection	5694048
40854066	40854089	15	-	27260156	A673	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.27903162781361157	[202]	[439,242,238,277]	6	hSpCas9	negative selection	5694049
40853557	40853580	15	+	27260156	A673	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.08429605342093201	[463]	[677,533,558,602]	2	hSpCas9	negative selection	5758302
40853503	40853526	15	-	27260156	A673	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.04115288600621825	[1042]	[1416,1369,1167,1205]	1	hSpCas9	negative selection	5758303
40854049	40854072	15	+	27260156	A673	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.3652163576807803	[93]	[219,112,97,160]	8	hSpCas9	negative selection	5758304
40853218	40853241	15	-	27260156	A375	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.6637155966367264	[1072]	[825,934,595,820]	-7	hSpCas9	negative selection	5815298
40853142	40853165	15	-	27260156	A375	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.3194049197685518	[732]	[1004,1132,1333,833]	5	hSpCas9	negative selection	5815299
40854066	40854089	15	-	27260156	A375	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.2696923186045914	[202]	[195,268,339,328]	4	hSpCas9	negative selection	5815300
40853557	40853580	15	+	27260156	A375	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.10596230762192389	[463]	[875,719,450,334]	1	hSpCas9	negative selection	5879553
40853503	40853526	15	-	27260156	A375	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.07714211658482029	[1042]	[1472,1472,1079,1152]	1	hSpCas9	negative selection	5879554
40854049	40854072	15	+	27260156	A375	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.3783423256400593	[93]	[54,88,109,83]	-5	hSpCas9	negative selection	5879555
40853218	40853241	15	-	27260156	COLO741	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	0.011542311893107282	[1072]	[1513,1413,1236]	0	hSpCas9	negative selection	5936549
40853142	40853165	15	-	27260156	COLO741	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.21941623949289424	[732]	[1297,828,1153]	4	hSpCas9	negative selection	5936550
40854066	40854089	15	-	27260156	COLO741	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.3254450753595277	[202]	[260,368,337]	6	hSpCas9	negative selection	5936551
40853557	40853580	15	+	27260156	COLO741	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.13900688557762758	[463]	[795,577,598]	3	hSpCas9	negative selection	6000804
40853503	40853526	15	-	27260156	COLO741	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.06456340154901863	[1042]	[1654,1367,1191]	1	hSpCas9	negative selection	6000805
40854049	40854072	15	+	27260156	COLO741	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.5822595523808387	[93]	[118,206,205]	9	hSpCas9	negative selection	6000806
40853218	40853241	15	-	27260156	CAL120	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.5546391590846185	[1072]	[1308,793,687]	-7	hSpCas9	negative selection	6057800
40853142	40853165	15	-	27260156	CAL120	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.254700557835429	[732]	[1338,927,1035]	4	hSpCas9	negative selection	6057801
40854066	40854089	15	-	27260156	CAL120	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.057537101991800066	[202]	[279,184,324]	0	hSpCas9	negative selection	6057802
40853557	40853580	15	+	27260156	CAL120	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.03353641739188942	[463]	[797,513,417]	0	hSpCas9	negative selection	6122055
40853503	40853526	15	-	27260156	CAL120	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.08589449696467599	[1042]	[1546,1429,1183]	1	hSpCas9	negative selection	6122056
40854049	40854072	15	+	27260156	CAL120	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.8353854120095494	[93]	[118,308,184]	9	hSpCas9	negative selection	6122057
40853218	40853241	15	-	27260156	CADOES1	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.5961315177387196	[1072]	[518,704,606,815]	-8	hSpCas9	negative selection	6179051
40853142	40853165	15	-	27260156	CADOES1	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.19563338642949413	[732]	[802,791,617,914]	3	hSpCas9	negative selection	6179052
40854066	40854089	15	-	27260156	CADOES1	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.014577656667606131	[202]	[168,184,215,192]	0	hSpCas9	negative selection	6179053
40853557	40853580	15	+	27260156	CADOES1	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.39413838369904536	[463]	[235,285,275,522]	-6	hSpCas9	negative selection	6243306
40853503	40853526	15	-	27260156	CADOES1	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.05992001918843548	[1042]	[1070,1055,748,842]	-1	hSpCas9	negative selection	6243307
40854049	40854072	15	+	27260156	CADOES1	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.8224193252438288	[93]	[97,73,376,65]	9	hSpCas9	negative selection	6243308
40853218	40853241	15	-	27260156	EWS502	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.2148571566229358	[1072]	[1176,943,866,894]	-4	hSpCas9	negative selection	6300302
40853142	40853165	15	-	27260156	EWS502	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.13069948165431822	[732]	[773,973,756,897]	2	hSpCas9	negative selection	6300303
40854066	40854089	15	-	27260156	EWS502	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.6652388962877405	[202]	[329,341,334,357]	9	hSpCas9	negative selection	6300304
40853557	40853580	15	+	27260156	EWS502	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.1577882447809326	[463]	[284,480,468,550]	-3	hSpCas9	negative selection	6364557
40853503	40853526	15	-	27260156	EWS502	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.03333975903793829	[1042]	[865,1173,1229,1066]	0	hSpCas9	negative selection	6364558
40854049	40854072	15	+	27260156	EWS502	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.2569589299684356	[93]	[33,114,120,66]	-4	hSpCas9	negative selection	6364559
40853218	40853241	15	-	27260156	EW8	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.6804227418922177	[1072]	[431,659,561,499]	-8	hSpCas9	negative selection	6421553
40853142	40853165	15	-	27260156	EW8	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.20310456112552877	[732]	[687,818,550,698]	4	hSpCas9	negative selection	6421554
40854066	40854089	15	-	27260156	EW8	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.12067669317001206	[202]	[168,224,137,188]	2	hSpCas9	negative selection	6421555
40853557	40853580	15	+	27260156	EW8	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.1283744440284156	[463]	[412,436,244,575]	2	hSpCas9	negative selection	6485808
40853503	40853526	15	-	27260156	EW8	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.05341836511914977	[1042]	[943,795,713,832]	-1	hSpCas9	negative selection	6485809
40854049	40854072	15	+	27260156	EW8	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.08949724216730015	[93]	[124,74,36,60]	-2	hSpCas9	negative selection	6485810
40853218	40853241	15	-	27260156	CORL105	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.2884520893889577	[1072]	[1058,783,1305,1013]	-5	hSpCas9	negative selection	6542804
40853142	40853165	15	-	27260156	CORL105	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.23569746407680636	[732]	[1051,949,942,1087]	4	hSpCas9	negative selection	6542805
40854066	40854089	15	-	27260156	CORL105	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.1782063488182144	[202]	[195,157,332,172]	-3	hSpCas9	negative selection	6542806
40853557	40853580	15	+	27260156	CORL105	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.03387685282426957	[463]	[503,582,465,556]	0	hSpCas9	negative selection	6607059
40853503	40853526	15	-	27260156	CORL105	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.07483614166551766	[1042]	[1474,1117,1338,1229]	1	hSpCas9	negative selection	6607060
40854049	40854072	15	+	27260156	CORL105	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.05531589882337995	[93]	[167,79,95,112]	1	hSpCas9	negative selection	6607061
40853218	40853241	15	-	27260156	HS294T	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.6576264844822464	[1072]	[181,301,288,288]	-7	hSpCas9	negative selection	6664055
40853142	40853165	15	-	27260156	HS294T	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.3033245510935828	[732]	[194,413,349,471]	4	hSpCas9	negative selection	6664056
40854066	40854089	15	-	27260156	HS294T	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.04804976627556701	[202]	[48,38,54,181]	0	hSpCas9	negative selection	6664057
40853557	40853580	15	+	27260156	HS294T	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.2840455266255254	[463]	[239,117,159,383]	4	hSpCas9	negative selection	6728310
40853503	40853526	15	-	27260156	HS294T	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.20106811726089113	[1042]	[205,371,483,353]	-3	hSpCas9	negative selection	6728311
40854049	40854072	15	+	27260156	HS294T	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.572689473012522	[93]	[11,13,34,40]	-7	hSpCas9	negative selection	6728312
40853218	40853241	15	-	27260156	HCC44	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.8953603598332844	[1072]	[517,593,830,686]	-8	hSpCas9	negative selection	6785306
40853142	40853165	15	-	27260156	HCC44	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.10143531667146144	[732]	[938,613,1076,992]	1	hSpCas9	negative selection	6785307
40854066	40854089	15	-	27260156	HCC44	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.0704919643914299	[202]	[254,143,182,295]	-1	hSpCas9	negative selection	6785308
40853557	40853580	15	+	27260156	HCC44	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.2331097912447452	[463]	[400,775,325,214]	-4	hSpCas9	negative selection	6849561
40853503	40853526	15	-	27260156	HCC44	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.4025948120867734	[1042]	[1054,869,769,864]	-6	hSpCas9	negative selection	6849562
40854049	40854072	15	+	27260156	HCC44	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.09432412859378347	[93]	[75,94,115,163]	1	hSpCas9	negative selection	6849563
40853218	40853241	15	-	27260156	G402	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.6401688711670575	[1072]	[851,792,1081,638]	-7	hSpCas9	negative selection	6906557
40853142	40853165	15	-	27260156	G402	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.33100012951503643	[732]	[1199,617,1592,1068]	4	hSpCas9	negative selection	6906558
40854066	40854089	15	-	27260156	G402	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.08450398057228714	[202]	[288,89,231,317]	-1	hSpCas9	negative selection	6906559
40853557	40853580	15	+	27260156	G402	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.6101469547505608	[463]	[444,474,250,329]	-6	hSpCas9	negative selection	6970812
40853503	40853526	15	-	27260156	G402	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.3246568874973085	[1042]	[1145,1034,973,929]	-4	hSpCas9	negative selection	6970813
40854049	40854072	15	+	27260156	G402	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-1.298468999878907	[93]	[111,13,65,3]	-9	hSpCas9	negative selection	6970814
40853218	40853241	15	-	27260156	L33	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.32382577574224736	[1072]	[871,381,518,798]	-6	hSpCas9	negative selection	7027808
40853142	40853165	15	-	27260156	L33	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.0036978155182497696	[732]	[869,265,488,639]	0	hSpCas9	negative selection	7027809
40854066	40854089	15	-	27260156	L33	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.2773614062026506	[202]	[141,77,106,167]	-6	hSpCas9	negative selection	7027810
40853557	40853580	15	+	27260156	L33	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.2511313972070855	[463]	[313,168,303,351]	-5	hSpCas9	negative selection	7092063
40853503	40853526	15	-	27260156	L33	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.1320418417391147	[1042]	[984,422,531,941]	-3	hSpCas9	negative selection	7092064
40854049	40854072	15	+	27260156	L33	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.5068007087380728	[93]	[109,58,62,179]	8	hSpCas9	negative selection	7092065
40853218	40853241	15	-	27260156	K562	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.9965243595623234	[1072]	[279,423,432,721]	-8	hSpCas9	negative selection	7149059
40853142	40853165	15	-	27260156	K562	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-0.08031291488658576	[732]	[682,617,527,632]	-1	hSpCas9	negative selection	7149060
40854066	40854089	15	-	27260156	K562	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.11486441099290223	[202]	[133,216,262,62]	-1	hSpCas9	negative selection	7149061
40853557	40853580	15	+	27260156	K562	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.19478589106464012	[463]	[252,620,156,405]	-2	hSpCas9	negative selection	7213314
40853503	40853526	15	-	27260156	K562	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.06258176781225044	[1042]	[863,582,1372,722]	-1	hSpCas9	negative selection	7213315
40854049	40854072	15	+	27260156	K562	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.851856275448017	[93]	[48,9,39,79]	-7	hSpCas9	negative selection	7213316
40853218	40853241	15	-	27260156	HT29	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.16959567461114555	[1072]	[1190,1077,1172,1180]	-3	hSpCas9	negative selection	7270310
40853142	40853165	15	-	27260156	HT29	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.17240411447701187	[732]	[918,1013,1177,904]	3	hSpCas9	negative selection	7270311
40854066	40854089	15	-	27260156	HT29	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.5299137395928856	[202]	[443,396,308,290]	8	hSpCas9	negative selection	7270312
40853557	40853580	15	+	27260156	HT29	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.09204149493599618	[463]	[620,736,502,557]	1	hSpCas9	negative selection	7334565
40853503	40853526	15	-	27260156	HT29	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.10207454220261614	[1042]	[1391,1575,1445,1075]	2	hSpCas9	negative selection	7334566
40854049	40854072	15	+	27260156	HT29	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.029517978471383266	[93]	[64,284,79,53]	0	hSpCas9	negative selection	7334567
40853218	40853241	15	-	27260156	MHHES1	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.17273082184590605	[1072]	[1193,1231,1150,785]	-3	hSpCas9	negative selection	7391561
40853142	40853165	15	-	27260156	MHHES1	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.29940760081177764	[732]	[1217,990,1003,880]	5	hSpCas9	negative selection	7391562
40854066	40854089	15	-	27260156	MHHES1	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.19836153600790873	[202]	[195,249,197,161]	-4	hSpCas9	negative selection	7391563
40853557	40853580	15	+	27260156	MHHES1	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.019646138835369007	[463]	[426,584,527,553]	0	hSpCas9	negative selection	7455816
40853503	40853526	15	-	27260156	MHHES1	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.017073444746892763	[1042]	[1144,1634,1122,925]	0	hSpCas9	negative selection	7455817
40854049	40854072	15	+	27260156	MHHES1	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.30048743744462536	[93]	[71,128,166,140]	5	hSpCas9	negative selection	7455818
40853218	40853241	15	-	27260156	MEWO	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.04214133607042014	[1072]	[1002,993,932]	-1	hSpCas9	negative selection	7512812
40853142	40853165	15	-	27260156	MEWO	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.15294196517252667	[732]	[933,647,738]	3	hSpCas9	negative selection	7512813
40854066	40854089	15	-	27260156	MEWO	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.059926577195181574	[202]	[143,209,184]	-1	hSpCas9	negative selection	7512814
40853557	40853580	15	+	27260156	MEWO	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.0896910185991895	[463]	[424,411,389]	-2	hSpCas9	negative selection	7577067
40853503	40853526	15	-	27260156	MEWO	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.0818098880135334	[1042]	[1077,718,999]	-2	hSpCas9	negative selection	7577068
40854049	40854072	15	+	27260156	MEWO	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.4078769086080274	[93]	[198,106,59]	8	hSpCas9	negative selection	7577069
40853218	40853241	15	-	27260156	LNCAPCLONEFGC	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.13811790815223257	[1072]	[921,925,823,847]	-2	hSpCas9	negative selection	7634063
40853142	40853165	15	-	27260156	LNCAPCLONEFGC	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.5406551964767828	[732]	[764,891,1035,1188]	8	hSpCas9	negative selection	7634064
40854066	40854089	15	-	27260156	LNCAPCLONEFGC	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.4999586195166429	[202]	[251,280,220,278]	7	hSpCas9	negative selection	7634065
40853557	40853580	15	+	27260156	LNCAPCLONEFGC	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.22744021914397886	[463]	[458,503,620,402]	3	hSpCas9	negative selection	7698318
40853503	40853526	15	-	27260156	LNCAPCLONEFGC	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.13844865421655506	[1042]	[1046,887,1153,1096]	2	hSpCas9	negative selection	7698319
40854049	40854072	15	+	27260156	LNCAPCLONEFGC	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.3234995459120005	[93]	[52,60,61,95]	-5	hSpCas9	negative selection	7698320
40853218	40853241	15	-	27260156	PANC0327	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.9699096325253524	[1072]	[424,279,584,677]	-8	hSpCas9	negative selection	7755314
40853142	40853165	15	-	27260156	PANC0327	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-0.4334533619992997	[732]	[546,387,520,489]	-6	hSpCas9	negative selection	7755315
40854066	40854089	15	-	27260156	PANC0327	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.22381557890988235	[202]	[126,89,319,86]	-3	hSpCas9	negative selection	7755316
40853557	40853580	15	+	27260156	PANC0327	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.06796264174631836	[463]	[386,380,490,314]	-1	hSpCas9	negative selection	7819569
40853503	40853526	15	-	27260156	PANC0327	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.686477380794277	[1042]	[565,551,628,557]	-7	hSpCas9	negative selection	7819570
40854049	40854072	15	+	27260156	PANC0327	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.8221256597489881	[93]	[70,100,91,325]	9	hSpCas9	negative selection	7819571
40853218	40853241	15	-	27260156	NCIH2009	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.5542619192279477	[1072]	[1343,1015,764]	-6	hSpCas9	negative selection	7876565
40853142	40853165	15	-	27260156	NCIH2009	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.18944892299304372	[732]	[1293,1136,1095]	2	hSpCas9	negative selection	7876566
40854066	40854089	15	-	27260156	NCIH2009	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.10708886339316526	[202]	[354,189,263]	-1	hSpCas9	negative selection	7876567
40853557	40853580	15	+	27260156	NCIH2009	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.49115466680826153	[463]	[457,529,392]	-6	hSpCas9	negative selection	7940820
40853503	40853526	15	-	27260156	NCIH2009	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.17541477040787234	[1042]	[1913,1764,1305]	2	hSpCas9	negative selection	7940821
40854049	40854072	15	+	27260156	NCIH2009	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.6876010613083627	[93]	[153,202,265]	8	hSpCas9	negative selection	7940822
40853218	40853241	15	-	27260156	NCIH1373	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-1.3643612282801545	[1072]	[764,313,348,132]	-8	hSpCas9	negative selection	7997816
40853142	40853165	15	-	27260156	NCIH1373	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-0.34145090803496786	[732]	[514,567,724,203]	-3	hSpCas9	negative selection	7997817
40854066	40854089	15	-	27260156	NCIH1373	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.9284964524539989	[202]	[221,110,93,16]	-7	hSpCas9	negative selection	7997818
40853557	40853580	15	+	27260156	NCIH1373	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.9184392259218214	[463]	[118,442,168,86]	-7	hSpCas9	negative selection	8062071
40853503	40853526	15	-	27260156	NCIH1373	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.4888583078856946	[1042]	[914,515,845,292]	-5	hSpCas9	negative selection	8062072
40854049	40854072	15	+	27260156	NCIH1373	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.20896443511673368	[93]	[212,32,115,5]	-2	hSpCas9	negative selection	8062073
40853218	40853241	15	-	27260156	PATU8902	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-1.0290941634268678	[1072]	[1049,552,655,671]	-7	hSpCas9	negative selection	8119067
40853142	40853165	15	-	27260156	PATU8902	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.32637866974414564	[732]	[1735,789,1122,1522]	3	hSpCas9	negative selection	8119068
40854066	40854089	15	-	27260156	PATU8902	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.6297747040585746	[202]	[226,219,132,158]	-6	hSpCas9	negative selection	8119069
40853557	40853580	15	+	27260156	PATU8902	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.6699087369433604	[463]	[512,418,329,373]	-6	hSpCas9	negative selection	8183322
40853503	40853526	15	-	27260156	PATU8902	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.5966993629785445	[1042]	[955,972,826,1133]	-5	hSpCas9	negative selection	8183323
40854049	40854072	15	+	27260156	PATU8902	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.8057437714901607	[93]	[180,49,7,75]	-6	hSpCas9	negative selection	8183324
40853218	40853241	15	-	27260156	PANC1	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	0.05969138590661238	[1072]	[915,1160,769,1010]	0	hSpCas9	negative selection	8240318
40853142	40853165	15	-	27260156	PANC1	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.34295165088219026	[732]	[986,780,774,653]	5	hSpCas9	negative selection	8240319
40854066	40854089	15	-	27260156	PANC1	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.28995925775629205	[202]	[214,353,226,100]	4	hSpCas9	negative selection	8240320
40853557	40853580	15	+	27260156	PANC1	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.15714625411210242	[463]	[390,604,583,256]	2	hSpCas9	negative selection	8304573
40853503	40853526	15	-	27260156	PANC1	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.04946855133741157	[1042]	[893,898,876,795]	-1	hSpCas9	negative selection	8304574
40854049	40854072	15	+	27260156	PANC1	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.05672758959578017	[93]	[115,107,31,60]	-1	hSpCas9	negative selection	8304575
40853218	40853241	15	-	27260156	PANC0813	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.9202283659516474	[1072]	[762,712,644,556]	-8	hSpCas9	negative selection	8361569
40853142	40853165	15	-	27260156	PANC0813	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-0.0770104116228596	[732]	[784,972,684,816]	-1	hSpCas9	negative selection	8361570
40854066	40854089	15	-	27260156	PANC0813	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.36595336032869974	[202]	[317,110,104,215]	-5	hSpCas9	negative selection	8361571
40853557	40853580	15	+	27260156	PANC0813	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.7048320459496759	[463]	[458,350,222,315]	-7	hSpCas9	negative selection	8425824
40853503	40853526	15	-	27260156	PANC0813	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.29794860591563166	[1042]	[1027,1303,783,876]	-5	hSpCas9	negative selection	8425825
40854049	40854072	15	+	27260156	PANC0813	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.08667804717082994	[93]	[81,73,244,67]	1	hSpCas9	negative selection	8425826
40853218	40853241	15	-	27260156	RDES	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.735661875190754	[1072]	[700,500,864,940]	-8	hSpCas9	negative selection	8482820
40853142	40853165	15	-	27260156	RDES	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.4044533590400251	[732]	[881,1007,1120,1545]	6	hSpCas9	negative selection	8482821
40854066	40854089	15	-	27260156	RDES	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.30779396284895955	[202]	[287,242,305,318]	5	hSpCas9	negative selection	8482822
40853557	40853580	15	+	27260156	RDES	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.46375304424324315	[463]	[320,400,356,482]	-7	hSpCas9	negative selection	8547075
40853503	40853526	15	-	27260156	RDES	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.18459246003837093	[1042]	[884,1057,1077,1231]	-3	hSpCas9	negative selection	8547076
40854049	40854072	15	+	27260156	RDES	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.07187963803662223	[93]	[62,147,101,98]	-1	hSpCas9	negative selection	8547077
40853218	40853241	15	-	27260156	PC3	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.27449571340111045	[1072]	[520,982,1389,911]	-6	hSpCas9	negative selection	8604071
40853142	40853165	15	-	27260156	PC3	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.07409230293805469	[732]	[621,673,1108,779]	1	hSpCas9	negative selection	8604072
40854066	40854089	15	-	27260156	PC3	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.3043142183688039	[202]	[133,198,430,342]	6	hSpCas9	negative selection	8604073
40853557	40853580	15	+	27260156	PC3	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.23066356564661472	[463]	[297,307,581,466]	-5	hSpCas9	negative selection	8668326
40853503	40853526	15	-	27260156	PC3	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	0.011505529813321091	[1042]	[977,630,2056,819]	0	hSpCas9	negative selection	8668327
40854049	40854072	15	+	27260156	PC3	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.17319264944178414	[93]	[58,62,120,107]	-4	hSpCas9	negative selection	8668328
40853218	40853241	15	-	27260156	PATU8988T	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.3240078101564394	[1072]	[843,713,758,999]	-5	hSpCas9	negative selection	8725322
40853142	40853165	15	-	27260156	PATU8988T	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.45571048256525015	[732]	[1214,913,964,769]	7	hSpCas9	negative selection	8725323
40854066	40854089	15	-	27260156	PATU8988T	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.20219561664997743	[202]	[176,291,103,116]	-3	hSpCas9	negative selection	8725324
40853557	40853580	15	+	27260156	PATU8988T	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.39863873959740354	[463]	[436,627,503,817]	6	hSpCas9	negative selection	8789577
40853503	40853526	15	-	27260156	PATU8988T	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.31621530986690727	[1042]	[1056,846,542,796]	-5	hSpCas9	negative selection	8789578
40854049	40854072	15	+	27260156	PATU8988T	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.1824941697823279	[93]	[117,50,124,113]	3	hSpCas9	negative selection	8789579
40853218	40853241	15	-	27260156	T47D	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.38556278585709536	[1072]	[868,980,970,1004]	-7	hSpCas9	negative selection	8846573
40853142	40853165	15	-	27260156	T47D	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.1240429929129212	[732]	[898,786,943,1109]	2	hSpCas9	negative selection	8846574
40854066	40854089	15	-	27260156	T47D	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.08909123657807427	[202]	[286,195,270,256]	1	hSpCas9	negative selection	8846575
40853557	40853580	15	+	27260156	T47D	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.2633318847203738	[463]	[387,430,520,461]	-5	hSpCas9	negative selection	8910828
40853503	40853526	15	-	27260156	T47D	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.11310422334481762	[1042]	[1118,1132,1110,1129]	-3	hSpCas9	negative selection	8910829
40854049	40854072	15	+	27260156	T47D	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.1311781237725902	[93]	[105,99,94,98]	-3	hSpCas9	negative selection	8910830
40853218	40853241	15	-	27260156	SU8686	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.25995763882629275	[1072]	[857,707,824,1237]	-4	hSpCas9	negative selection	8967824
40853142	40853165	15	-	27260156	SU8686	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.16016030201118248	[732]	[799,705,786,992]	2	hSpCas9	negative selection	8967825
40854066	40854089	15	-	27260156	SU8686	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.07362966938756488	[202]	[243,160,230,113]	-1	hSpCas9	negative selection	8967826
40853557	40853580	15	+	27260156	SU8686	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.20110756962603948	[463]	[399,421,228,565]	-4	hSpCas9	negative selection	9032079
40853503	40853526	15	-	27260156	SU8686	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.0990060795909109	[1042]	[847,735,1160,1195]	-2	hSpCas9	negative selection	9032080
40854049	40854072	15	+	27260156	SU8686	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.17060455636564065	[93]	[90,67,111,163]	3	hSpCas9	negative selection	9032081
40853218	40853241	15	-	27260156	SKES1	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.5140832204573058	[1072]	[855,795,732,638]	-8	hSpCas9	negative selection	9089075
40853142	40853165	15	-	27260156	SKES1	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.18431587775394365	[732]	[848,776,871,813]	4	hSpCas9	negative selection	9089076
40854066	40854089	15	-	27260156	SKES1	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.5511078061849107	[202]	[305,372,248,269]	9	hSpCas9	negative selection	9089077
40853557	40853580	15	+	27260156	SKES1	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.14185249187919907	[463]	[506,330,395,438]	-3	hSpCas9	negative selection	9153330
40853503	40853526	15	-	27260156	SKES1	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.07130489292211983	[1042]	[1219,787,976,974]	-1	hSpCas9	negative selection	9153331
40854049	40854072	15	+	27260156	SKES1	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.16916474306031226	[93]	[84,150,96,91]	3	hSpCas9	negative selection	9153332
40853218	40853241	15	-	27260156	TOV112D	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.4229155666355843	[1072]	[1045,1072,535,641]	-7	hSpCas9	negative selection	9210326
40853142	40853165	15	-	27260156	TOV112D	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.1731995970893001	[732]	[1193,728,627,766]	3	hSpCas9	negative selection	9210327
40854066	40854089	15	-	27260156	TOV112D	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.6117710450870646	[202]	[448,401,209,217]	9	hSpCas9	negative selection	9210328
40853557	40853580	15	+	27260156	TOV112D	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.21518322964761047	[463]	[381,468,400,364]	-4	hSpCas9	negative selection	9274581
40853503	40853526	15	-	27260156	TOV112D	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.264878612936123	[1042]	[857,1053,824,785]	-5	hSpCas9	negative selection	9274582
40854049	40854072	15	+	27260156	TOV112D	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.18002031012166686	[93]	[105,164,59,24]	-4	hSpCas9	negative selection	9274583
40853218	40853241	15	-	27260156	TC71	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.24231032018283183	[1072]	[871,951,968,1106]	-6	hSpCas9	negative selection	9331577
40853142	40853165	15	-	27260156	TC71	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.04204318845241328	[732]	[753,831,631,1038]	1	hSpCas9	negative selection	9331578
40854066	40854089	15	-	27260156	TC71	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	0.3917315786667599	[202]	[240,333,242,328]	8	hSpCas9	negative selection	9331579
40853557	40853580	15	+	27260156	TC71	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.14942107222618586	[463]	[418,461,482,427]	-4	hSpCas9	negative selection	9395832
40853503	40853526	15	-	27260156	TC71	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.06836159948507392	[1042]	[820,1196,990,1276]	-2	hSpCas9	negative selection	9395833
40854049	40854072	15	+	27260156	TC71	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	0.46669815707388995	[93]	[121,127,111,199]	9	hSpCas9	negative selection	9395834
40853218	40853241	15	-	27260156	TC32	viability	CATCCGTGTCACCCCGCAGTAGG	SPINT1	ENSG00000166145	-0.38708878723782514	[1072]	[767,631,964,756]	-6	hSpCas9	negative selection	9452828
40853142	40853165	15	-	27260156	TC32	viability	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.43084591603061473	[732]	[761,979,897,1013]	7	hSpCas9	negative selection	9452829
40854066	40854089	15	-	27260156	TC32	viability	ACCTGGATGGCGCCTTTCCATGG	SPINT1	ENSG00000166145	-0.08368786205086409	[202]	[188,86,221,257]	-1	hSpCas9	negative selection	9452830
40853557	40853580	15	+	27260156	TC32	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.25614450697250496	[463]	[292,215,578,460]	-5	hSpCas9	negative selection	9517083
40853503	40853526	15	-	27260156	TC32	viability	TGAGTCCCCACAGTTCCACCTGG	SPINT1	ENSG00000166145	-0.06000203079387645	[1042]	[989,611,1310,976]	-1	hSpCas9	negative selection	9517084
40854049	40854072	15	+	27260156	TC32	viability	CTCTCTCCCAGGCCCCTCCATGG	SPINT1	ENSG00000166145	-0.7788578717085066	[93]	[47,25,103,43]	-9	hSpCas9	negative selection	9517085
40844747	40844770	15	+	27869803	HPAFII	viability after 27 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.2140603376681466	[208]	[145,111,NaN]	1	hSpCas9	negative selection	9553479
40853142	40853165	15	-	27869803	HPAFII	viability after 27 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-1.7948855700953874	[71]	[5,14,NaN]	-8	hSpCas9	negative selection	9553480
40853606	40853629	15	+	27869803	HPAFII	viability after 27 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	1.1492942428940531	[358]	[320,499,NaN]	8	hSpCas9	negative selection	9553481
40853745	40853768	15	-	27869803	HPAFII	viability after 27 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	0.4299295135079162	[152]	[13,186,NaN]	3	hSpCas9	negative selection	9553482
40854068	40854091	15	+	27869803	HPAFII	viability after 27 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	0.11200502551313107	[123]	[106,39,NaN]	0	hSpCas9	negative selection	9553483
40854626	40854649	15	+	27869803	HPAFII	viability after 27 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	0.9508997249608286	[211]	[149,269,NaN]	7	hSpCas9	negative selection	9553484
40844747	40844770	15	+	27869803	HPAFII	viability after 15 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.5017018260410755	[208]	[494,207,NaN]	6	hSpCas9	negative selection	9635928
40853142	40853165	15	-	27869803	HPAFII	viability after 15 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-0.3725419713470124	[71]	[97,35,NaN]	-4	hSpCas9	negative selection	9635929
40853606	40853629	15	+	27869803	HPAFII	viability after 15 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	-0.21411324925571207	[358]	[294,355,NaN]	-2	hSpCas9	negative selection	9635930
40853745	40853768	15	-	27869803	HPAFII	viability after 15 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-0.8256333724007253	[152]	[48,119,NaN]	-7	hSpCas9	negative selection	9635931
40854068	40854091	15	+	27869803	HPAFII	viability after 15 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	-0.09212124498898966	[123]	[190,83,NaN]	-1	hSpCas9	negative selection	9635932
40854626	40854649	15	+	27869803	HPAFII	viability after 15 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	0.3500169484205614	[211]	[319,271,NaN]	4	hSpCas9	negative selection	9635933
40844747	40844770	15	+	27869803	ASPC1	viability after 36 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.30744118044818614	[545]	[270,101,314]	3	hSpCas9	negative selection	9718377
40853142	40853165	15	-	27869803	ASPC1	viability after 36 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	0.8753904937702743	[68]	[66,0,61]	8	hSpCas9	negative selection	9718378
40853606	40853629	15	+	27869803	ASPC1	viability after 36 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	0.8015835071432411	[737]	[447,472,425]	7	hSpCas9	negative selection	9718379
40853745	40853768	15	-	27869803	ASPC1	viability after 36 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	0.07191878294156295	[423]	[395,102,26]	0	hSpCas9	negative selection	9718380
40854068	40854091	15	+	27869803	ASPC1	viability after 36 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	-0.39131773410557713	[345]	[277,0,32]	-4	hSpCas9	negative selection	9718381
40854626	40854649	15	+	27869803	ASPC1	viability after 36 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	1.1600764431215815	[302]	[270,192,243]	9	hSpCas9	negative selection	9718382
40844747	40844770	15	+	27869803	PATU8988S	viability after 35 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	-1.5179295475840782	[600]	[93,74,NaN]	-8	hSpCas9	negative selection	9800826
40853142	40853165	15	-	27869803	PATU8988S	viability after 35 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-1.8930716538307988	[82]	[8,8,NaN]	-9	hSpCas9	negative selection	9800827
40853606	40853629	15	+	27869803	PATU8988S	viability after 35 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	-0.002298320768234524	[501]	[139,263,NaN]	0	hSpCas9	negative selection	9800828
40853745	40853768	15	-	27869803	PATU8988S	viability after 35 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-0.7521918232396309	[340]	[97,64,NaN]	-6	hSpCas9	negative selection	9800829
40854068	40854091	15	+	27869803	PATU8988S	viability after 35 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	0.4757800898497567	[242]	[180,90,NaN]	5	hSpCas9	negative selection	9800830
40854626	40854649	15	+	27869803	PATU8988S	viability after 35 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.20774260693209834	[364]	[34,219,NaN]	-2	hSpCas9	negative selection	9800831
40844747	40844770	15	+	27869803	PATU8988S	viability after 31 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	-1.0503308135467986	[600]	[87,150,NaN]	-8	hSpCas9	negative selection	9883275
40853142	40853165	15	-	27869803	PATU8988S	viability after 31 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-2.2006662089075513	[82]	[4,9,NaN]	-9	hSpCas9	negative selection	9883276
40853606	40853629	15	+	27869803	PATU8988S	viability after 31 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	0.6596978918124481	[501]	[207,453,NaN]	7	hSpCas9	negative selection	9883277
40853745	40853768	15	-	27869803	PATU8988S	viability after 31 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	-0.5101259036389153	[340]	[65,132,NaN]	-5	hSpCas9	negative selection	9883278
40854068	40854091	15	+	27869803	PATU8988S	viability after 31 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	0.5022633960603639	[242]	[160,106,NaN]	6	hSpCas9	negative selection	9883279
40854626	40854649	15	+	27869803	PATU8988S	viability after 31 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	-0.4177916018087491	[364]	[49,183,NaN]	-5	hSpCas9	negative selection	9883280
40844747	40844770	15	+	27869803	HPAFII	viability after 35 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.9141309057066527	[208]	[141,263,NaN]	6	hSpCas9	negative selection	9965724
40853142	40853165	15	-	27869803	HPAFII	viability after 35 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-1.6834924079327658	[71]	[0,22,NaN]	-7	hSpCas9	negative selection	9965725
40853606	40853629	15	+	27869803	HPAFII	viability after 35 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	2.026608294796253	[358]	[446,1070,NaN]	9	hSpCas9	negative selection	9965726
40853745	40853768	15	-	27869803	HPAFII	viability after 35 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	1.2443214253198587	[152]	[0,388,NaN]	8	hSpCas9	negative selection	9965727
40854068	40854091	15	+	27869803	HPAFII	viability after 35 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	-0.34165716141250635	[123]	[65,30,NaN]	-2	hSpCas9	negative selection	9965728
40854626	40854649	15	+	27869803	HPAFII	viability after 35 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	1.2171440944661303	[211]	[217,284,NaN]	7	hSpCas9	negative selection	9965729
40844747	40844770	15	+	27869803	HPAFII	viability after 31 days	ACCAACGCCTCGGTCAGCAACGG	SPINT1	ENSG00000166145	0.3966744877973549	[208]	[118,192,NaN]	3	hSpCas9	negative selection	10048173
40853142	40853165	15	-	27869803	HPAFII	viability after 31 days	CTTCAAGTCTATGCCTGCCCAGG	SPINT1	ENSG00000166145	-1.6943473492114227	[71]	[0,24,NaN]	-7	hSpCas9	negative selection	10048174
40853606	40853629	15	+	27869803	HPAFII	viability after 31 days	CTGTCCACCAAGCAGACAGAAGG	SPINT1	ENSG00000166145	1.158693926664308	[358]	[277,636,NaN]	8	hSpCas9	negative selection	10048175
40853745	40853768	15	-	27869803	HPAFII	viability after 31 days	ACCAGCGTGGGAAAGAGCCCCGG	SPINT1	ENSG00000166145	0.9054914156457718	[152]	[0,334,NaN]	6	hSpCas9	negative selection	10048176
40854068	40854091	15	+	27869803	HPAFII	viability after 31 days	ATGGAAAGGCGCCATCCAGGTGG	SPINT1	ENSG00000166145	0.177990284175922	[123]	[94,60,NaN]	1	hSpCas9	negative selection	10048177
40854626	40854649	15	+	27869803	HPAFII	viability after 31 days	TTCCTCTCTGCAGACACGAGTGG	SPINT1	ENSG00000166145	0.8553680461144847	[211]	[153,281,NaN]	6	hSpCas9	negative selection	10048178
40844610	40844633	15	-	28162770	P31FUJ	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	-0.006526348590702558	[105]	[123]	0	hSpCas9	negative selection	10242141
40855938	40855961	15	-	28162770	P31FUJ	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	-0.03688199443912188	[109]	[125]	0	hSpCas9	negative selection	10242142
40844895	40844918	15	-	28162770	P31FUJ	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-1.6981830893828622	[242]	[87]	-8	hSpCas9	negative selection	10242143
40844718	40844741	15	-	28162770	P31FUJ	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	0.3853271602419768	[42]	[65]	4	hSpCas9	negative selection	10242144
40844858	40844881	15	+	28162770	P31FUJ	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	-0.35925053965531795	[142]	[130]	-3	hSpCas9	negative selection	10242145
40853488	40853511	15	+	28162770	P31FUJ	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-0.0963830061877835	[120]	[132]	-1	hSpCas9	negative selection	10242146
40853510	40853533	15	+	28162770	P31FUJ	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	-0.43371489834037513	[99]	[86]	-4	hSpCas9	negative selection	10242147
40853557	40853580	15	+	28162770	P31FUJ	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.10397365488029699	[231]	[292]	1	hSpCas9	negative selection	10242148
40853838	40853861	15	-	28162770	P31FUJ	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.23616121650429334	[429]	[428]	-2	hSpCas9	negative selection	10242149
40855925	40855948	15	+	28162770	P31FUJ	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-0.5199003151386419	[132]	[108]	-4	hSpCas9	negative selection	10242150
40844610	40844633	15	-	28162770	TF1	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10411507
40855938	40855961	15	-	28162770	TF1	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10411508
40844895	40844918	15	-	28162770	TF1	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10411509
40844718	40844741	15	-	28162770	TF1	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10411510
40844858	40844881	15	+	28162770	TF1	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	NaN	[NaN]	[123]	1	hSpCas9	negative selection	10411511
40853488	40853511	15	+	28162770	TF1	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	NaN	[NaN]	[146]	1	hSpCas9	negative selection	10411512
40853510	40853533	15	+	28162770	TF1	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10411513
40853557	40853580	15	+	28162770	TF1	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	NaN	[NaN]	[163]	1	hSpCas9	negative selection	10411514
40853838	40853861	15	-	28162770	TF1	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	NaN	[NaN]	[297]	1	hSpCas9	negative selection	10411515
40855925	40855948	15	+	28162770	TF1	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	NaN	[NaN]	[16]	1	hSpCas9	negative selection	10411516
40844610	40844633	15	-	28162770	SKM1	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	0.6780719051126377	[34]	[98]	6	hSpCas9	negative selection	10580873
40855938	40855961	15	-	28162770	SKM1	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	0.1290887014970481	[14]	[28]	1	hSpCas9	negative selection	10580874
40844895	40844918	15	-	28162770	SKM1	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-1.6520766965796931	[95]	[53]	-8	hSpCas9	negative selection	10580875
40844718	40844741	15	-	28162770	SKM1	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	-0.4069641987431618	[8]	[11]	-3	hSpCas9	negative selection	10580876
40844858	40844881	15	+	28162770	SKM1	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	0.1932650586313049	[46]	[94]	1	hSpCas9	negative selection	10580877
40853488	40853511	15	+	28162770	SKM1	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-0.9182170132813088	[30]	[28]	-6	hSpCas9	negative selection	10580878
40853510	40853533	15	+	28162770	SKM1	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	0.46340052084024275	[15]	[38]	4	hSpCas9	negative selection	10580879
40853557	40853580	15	+	28162770	SKM1	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.3238491684414494	[46]	[103]	3	hSpCas9	negative selection	10580880
40853838	40853861	15	-	28162770	SKM1	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.8608209469125336	[112]	[109]	-6	hSpCas9	negative selection	10580881
40855925	40855948	15	+	28162770	SKM1	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-0.32450203855118853	[33]	[47]	-3	hSpCas9	negative selection	10580882
40844610	40844633	15	-	28162770	SKM1	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	0.6780719051126377	[34]	[98]	6	hSpCas9	negative selection	10750239
40855938	40855961	15	-	28162770	SKM1	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	0.1290887014970481	[14]	[28]	1	hSpCas9	negative selection	10750240
40844895	40844918	15	-	28162770	SKM1	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-1.6520766965796931	[95]	[53]	-8	hSpCas9	negative selection	10750241
40844718	40844741	15	-	28162770	SKM1	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	-0.4069641987431618	[8]	[11]	-3	hSpCas9	negative selection	10750242
40844858	40844881	15	+	28162770	SKM1	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	0.1932650586313049	[46]	[94]	1	hSpCas9	negative selection	10750243
40853488	40853511	15	+	28162770	SKM1	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-0.9182170132813088	[30]	[28]	-6	hSpCas9	negative selection	10750244
40853510	40853533	15	+	28162770	SKM1	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	0.46340052084024275	[15]	[38]	4	hSpCas9	negative selection	10750245
40853557	40853580	15	+	28162770	SKM1	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.3238491684414494	[46]	[103]	3	hSpCas9	negative selection	10750246
40853838	40853861	15	-	28162770	SKM1	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.8608209469125336	[112]	[109]	-6	hSpCas9	negative selection	10750247
40855925	40855948	15	+	28162770	SKM1	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-0.32450203855118853	[33]	[47]	-3	hSpCas9	negative selection	10750248
40844610	40844633	15	-	28162770	PL21	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	0.5562834247145954	[124]	[79]	5	hSpCas9	negative selection	10919605
40855938	40855961	15	-	28162770	PL21	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	-2.455212214123234	[62]	[4]	-9	hSpCas9	negative selection	10919606
40844895	40844918	15	-	28162770	PL21	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-0.11301827077031018	[245]	[98]	-1	hSpCas9	negative selection	10919607
40844718	40844741	15	-	28162770	PL21	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	1.4328003712795951	[39]	[46]	9	hSpCas9	negative selection	10919608
40844858	40844881	15	+	28162770	PL21	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	-0.7509507850297334	[173]	[44]	-5	hSpCas9	negative selection	10919609
40853488	40853511	15	+	28162770	PL21	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-0.9113687007276704	[120]	[27]	-6	hSpCas9	negative selection	10919610
40853510	40853533	15	+	28162770	PL21	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	1.1754775602550511	[58]	[57]	8	hSpCas9	negative selection	10919611
40853557	40853580	15	+	28162770	PL21	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.9307497136157028	[181]	[150]	7	hSpCas9	negative selection	10919612
40853838	40853861	15	-	28162770	PL21	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.028561059315350912	[381]	[162]	0	hSpCas9	negative selection	10919613
40855925	40855948	15	+	28162770	PL21	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	0.1709932688298038	[99]	[48]	1	hSpCas9	negative selection	10919614
40844610	40844633	15	-	28162770	P31FUJ	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	-0.006526348590702558	[105]	[123]	0	hSpCas9	negative selection	11088971
40855938	40855961	15	-	28162770	P31FUJ	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	-0.03688199443912188	[109]	[125]	0	hSpCas9	negative selection	11088972
40844895	40844918	15	-	28162770	P31FUJ	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-1.6981830893828622	[242]	[87]	-8	hSpCas9	negative selection	11088973
40844718	40844741	15	-	28162770	P31FUJ	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	0.3853271602419768	[42]	[65]	4	hSpCas9	negative selection	11088974
40844858	40844881	15	+	28162770	P31FUJ	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	-0.35925053965531795	[142]	[130]	-3	hSpCas9	negative selection	11088975
40853488	40853511	15	+	28162770	P31FUJ	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-0.0963830061877835	[120]	[132]	-1	hSpCas9	negative selection	11088976
40853510	40853533	15	+	28162770	P31FUJ	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	-0.43371489834037513	[99]	[86]	-4	hSpCas9	negative selection	11088977
40853557	40853580	15	+	28162770	P31FUJ	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.10397365488029699	[231]	[292]	1	hSpCas9	negative selection	11088978
40853838	40853861	15	-	28162770	P31FUJ	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.23616121650429334	[429]	[428]	-2	hSpCas9	negative selection	11088979
40855925	40855948	15	+	28162770	P31FUJ	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-0.5199003151386419	[132]	[108]	-4	hSpCas9	negative selection	11088980
40844610	40844633	15	-	28162770	OCIAML5	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	0.5701664298190506	[49]	[133]	5	hSpCas9	negative selection	11258337
40855938	40855961	15	-	28162770	OCIAML5	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	-0.24063185878164983	[35]	[54]	-2	hSpCas9	negative selection	11258338
40844895	40844918	15	-	28162770	OCIAML5	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-1.1915530371356642	[123]	[97]	-6	hSpCas9	negative selection	11258339
40844718	40844741	15	-	28162770	OCIAML5	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	-1.9516022444149113	[29]	[13]	-8	hSpCas9	negative selection	11258340
40844858	40844881	15	+	28162770	OCIAML5	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	-0.48730227806637694	[72]	[93]	-3	hSpCas9	negative selection	11258341
40853488	40853511	15	+	28162770	OCIAML5	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-0.4859386720660996	[89]	[115]	-3	hSpCas9	negative selection	11258342
40853510	40853533	15	+	28162770	OCIAML5	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	-1.3259977591964092	[49]	[35]	-6	hSpCas9	negative selection	11258343
40853557	40853580	15	+	28162770	OCIAML5	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.6885018104987057	[87]	[255]	6	hSpCas9	negative selection	11258344
40853838	40853861	15	-	28162770	OCIAML5	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	0.15583862722134922	[272]	[548]	1	hSpCas9	negative selection	11258345
40855925	40855948	15	+	28162770	OCIAML5	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	0.09044793447524291	[63]	[122]	0	hSpCas9	negative selection	11258346
40844610	40844633	15	-	28162770	EOL1	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	-0.9667459689869653	[229]	[61]	-6	hSpCas9	negative selection	11427703
40855938	40855961	15	-	28162770	EOL1	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	0.11217477474630577	[71]	[40]	1	hSpCas9	negative selection	11427704
40844895	40844918	15	-	28162770	EOL1	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-0.11407352245677282	[529]	[257]	-1	hSpCas9	negative selection	11427705
40844718	40844741	15	-	28162770	EOL1	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	-1.3149181631248545	[84]	[17]	-7	hSpCas9	negative selection	11427706
40844858	40844881	15	+	28162770	EOL1	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	0.4373220725451752	[320]	[228]	4	hSpCas9	negative selection	11427707
40853488	40853511	15	+	28162770	EOL1	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-0.15140108166276411	[233]	[110]	-1	hSpCas9	negative selection	11427708
40853510	40853533	15	+	28162770	EOL1	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	0.5460361483168048	[64]	[49]	5	hSpCas9	negative selection	11427709
40853557	40853580	15	+	28162770	EOL1	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	1.2329926370942745	[171]	[212]	8	hSpCas9	negative selection	11427710
40853838	40853861	15	-	28162770	EOL1	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.0497350583210906	[555]	[282]	0	hSpCas9	negative selection	11427711
40855925	40855948	15	+	28162770	EOL1	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	0.2992275332332375	[144]	[93]	2	hSpCas9	negative selection	11427712
40844610	40844633	15	-	28162770	MOLM13	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	1.038424811630455	[133]	[198]	7	hSpCas9	negative selection	11597069
40855938	40855961	15	-	28162770	MOLM13	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	0.64297608810267	[92]	[104]	5	hSpCas9	negative selection	11597070
40844895	40844918	15	-	28162770	MOLM13	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-0.29662253950729	[422]	[248]	-2	hSpCas9	negative selection	11597071
40844718	40844741	15	-	28162770	MOLM13	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	0.9084619729305603	[69]	[94]	7	hSpCas9	negative selection	11597072
40844858	40844881	15	+	28162770	MOLM13	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	1.0752196952941895	[255]	[389]	7	hSpCas9	negative selection	11597073
40853488	40853511	15	+	28162770	MOLM13	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-0.319807014742557	[163]	[94]	-2	hSpCas9	negative selection	11597074
40853510	40853533	15	+	28162770	MOLM13	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	0.3423584994607196	[107]	[98]	2	hSpCas9	negative selection	11597075
40853557	40853580	15	+	28162770	MOLM13	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.4617891820081609	[236]	[235]	3	hSpCas9	negative selection	11597076
40853838	40853861	15	-	28162770	MOLM13	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.782529247100758	[796]	[334]	-4	hSpCas9	negative selection	11597077
40855925	40855948	15	+	28162770	MOLM13	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-0.4863069288422963	[123]	[63]	-3	hSpCas9	negative selection	11597078
40844610	40844633	15	-	28162770	HEL	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	-0.9263697175199621	[180]	[60]	-5	hSpCas9	negative selection	11766435
40855938	40855961	15	-	28162770	HEL	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	-1.0942267621658495	[99]	[29]	-6	hSpCas9	negative selection	11766436
40844895	40844918	15	-	28162770	HEL	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-0.8538285527750853	[363]	[128]	-5	hSpCas9	negative selection	11766437
40844718	40844741	15	-	28162770	HEL	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	1.0721316242562708	[74]	[100]	8	hSpCas9	negative selection	11766438
40844858	40844881	15	+	28162770	HEL	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	-0.7077584150837762	[254]	[99]	-4	hSpCas9	negative selection	11766439
40853488	40853511	15	+	28162770	HEL	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	0.20811060436363243	[172]	[127]	1	hSpCas9	negative selection	11766440
40853510	40853533	15	+	28162770	HEL	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	-0.5347993535518305	[94]	[41]	-4	hSpCas9	negative selection	11766441
40853557	40853580	15	+	28162770	HEL	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.36750397256103606	[189]	[156]	3	hSpCas9	negative selection	11766442
40853838	40853861	15	-	28162770	HEL	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.3242028794203473	[603]	[308]	-2	hSpCas9	negative selection	11766443
40855925	40855948	15	+	28162770	HEL	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-0.81669278663694	[131]	[47]	-5	hSpCas9	negative selection	11766444
40844610	40844633	15	-	28162770	MV411	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	0.05638925777470882	[128]	[112]	0	hSpCas9	negative selection	11935801
40855938	40855961	15	-	28162770	MV411	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	-0.32679854334532243	[66]	[44]	-2	hSpCas9	negative selection	11935802
40844895	40844918	15	-	28162770	MV411	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-1.2540399644352995	[234]	[82]	-7	hSpCas9	negative selection	11935803
40844718	40844741	15	-	28162770	MV411	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	0.7620107236125334	[55]	[79]	7	hSpCas9	negative selection	11935804
40844858	40844881	15	+	28162770	MV411	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	-0.10667094985373689	[169]	[132]	-1	hSpCas9	negative selection	11935805
40853488	40853511	15	+	28162770	MV411	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	-1.1966624140985314	[116]	[42]	-7	hSpCas9	negative selection	11935806
40853510	40853533	15	+	28162770	MV411	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	-0.8994038375464957	[61]	[27]	-6	hSpCas9	negative selection	11935807
40853557	40853580	15	+	28162770	MV411	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	-0.1979735975395873	[191]	[140]	-1	hSpCas9	negative selection	11935808
40853838	40853861	15	-	28162770	MV411	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.5348263903119984	[398]	[231]	-4	hSpCas9	negative selection	11935809
40855925	40855948	15	+	28162770	MV411	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-0.7525624492172248	[97]	[48]	-5	hSpCas9	negative selection	11935810
40844610	40844633	15	-	28162770	MONOMAC1	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	-0.9340024412257599	[69]	[41]	-6	hSpCas9	negative selection	12105167
40855938	40855961	15	-	28162770	MONOMAC1	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	-0.5955862235498288	[28]	[21]	-5	hSpCas9	negative selection	12105168
40844895	40844918	15	-	28162770	MONOMAC1	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	1.4263266480628976	[172]	[532]	9	hSpCas9	negative selection	12105169
40844718	40844741	15	-	28162770	MONOMAC1	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	-0.5955862235498288	[28]	[21]	-5	hSpCas9	negative selection	12105170
40844858	40844881	15	+	28162770	MONOMAC1	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	0.7071031375329302	[69]	[130]	6	hSpCas9	negative selection	12105171
40853488	40853511	15	+	28162770	MONOMAC1	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	0.755965673403277	[77]	[150]	7	hSpCas9	negative selection	12105172
40853510	40853533	15	+	28162770	MONOMAC1	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	-2.699537187588737	[33]	[5]	-9	hSpCas9	negative selection	12105173
40853557	40853580	15	+	28162770	MONOMAC1	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.18439225957647043	[75]	[98]	1	hSpCas9	negative selection	12105174
40853838	40853861	15	-	28162770	MONOMAC1	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	0.9433622020795869	[180]	[398]	8	hSpCas9	negative selection	12105175
40855925	40855948	15	+	28162770	MONOMAC1	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-1.3721235536176448	[69]	[30]	-8	hSpCas9	negative selection	12105176
40844610	40844633	15	-	28162770	OCIAML2	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	0.27660410437787203	[20]	[140]	2	hSpCas9	negative selection	12274533
40855938	40855961	15	-	28162770	OCIAML2	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	-1.383166983991822	[7]	[16]	-7	hSpCas9	negative selection	12274534
40844895	40844918	15	-	28162770	OCIAML2	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-0.5351700774368717	[39]	[152]	-4	hSpCas9	negative selection	12274535
40844718	40844741	15	-	28162770	OCIAML2	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	-0.8331999046268694	[8]	[27]	-5	hSpCas9	negative selection	12274536
40844858	40844881	15	+	28162770	OCIAML2	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	-0.024643737669815424	[48]	[266]	0	hSpCas9	negative selection	12274537
40853488	40853511	15	+	28162770	OCIAML2	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	0.07369069098164904	[23]	[139]	0	hSpCas9	negative selection	12274538
40853510	40853533	15	+	28162770	OCIAML2	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	-0.7544227912427526	[6]	[22]	-5	hSpCas9	negative selection	12274539
40853557	40853580	15	+	28162770	OCIAML2	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.055915989253673026	[20]	[120]	0	hSpCas9	negative selection	12274540
40853838	40853861	15	-	28162770	OCIAML2	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.34724740973687906	[69]	[304]	-3	hSpCas9	negative selection	12274541
40855925	40855948	15	+	28162770	OCIAML2	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-0.3381795292185117	[12]	[56]	-3	hSpCas9	negative selection	12274542
40844610	40844633	15	-	28162770	OCIAML3	viability	GCACAGAAGCCACAAGGCGACGG	SPINT1	ENSG00000166145	2.174176684452763	[31]	[435]	9	hSpCas9	negative selection	12443899
40855938	40855961	15	-	28162770	OCIAML3	viability	AGGGGTTGTAGTACCAGCGCGGG	SPINT1	ENSG00000166145	-0.19545826383388842	[10]	[28]	-1	hSpCas9	negative selection	12443900
40844895	40844918	15	-	28162770	OCIAML3	viability	GCAGTTGATGAGGAAGCAGGCGG	SPINT1	ENSG00000166145	-0.4504167866953133	[85]	[189]	-3	hSpCas9	negative selection	12443901
40844718	40844741	15	-	28162770	OCIAML3	viability	CACGAAGCCAGGCACCCCGGCGG	SPINT1	ENSG00000166145	-0.07943446749440497	[6]	[19]	0	hSpCas9	negative selection	12443902
40844858	40844881	15	+	28162770	OCIAML3	viability	GTGGAGCTGCAGCCCGACCGCGG	SPINT1	ENSG00000166145	0.7014482432020082	[43]	[215]	6	hSpCas9	negative selection	12443903
40853488	40853511	15	+	28162770	OCIAML3	viability	GAGGAAAGACCCAAACCAGGTGG	SPINT1	ENSG00000166145	0.22911459759175745	[25]	[91]	2	hSpCas9	negative selection	12443904
40853510	40853533	15	+	28162770	OCIAML3	viability	GAACTGTGGGGACTCAAGGAAGG	SPINT1	ENSG00000166145	-1.0634929236253832	[17]	[25]	-6	hSpCas9	negative selection	12443905
40853557	40853580	15	+	28162770	OCIAML3	viability	GACTAGCTCAGACCACCCAGAGG	SPINT1	ENSG00000166145	0.3404040180482599	[44]	[171]	3	hSpCas9	negative selection	12443906
40853838	40853861	15	-	28162770	OCIAML3	viability	GAATGCACTCTTCTTCCCGAAGG	SPINT1	ENSG00000166145	-0.8522007830884581	[118]	[198]	-6	hSpCas9	negative selection	12443907
40855925	40855948	15	+	28162770	OCIAML3	viability	GCAAGGAGAGCATCCCGCGCTGG	SPINT1	ENSG00000166145	-0.2902268921470601	[31]	[78]	-2	hSpCas9	negative selection	12443908