Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10653
• Symbol:SPINT2
• Description:serine peptidase inhibitor, Kunitz type 2

DataSource: http://genomecrispr.dkfz.de/#!/results/SPINT2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
38287882	38287905	19	-	26472758	Jiyoye	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	0.3272070768024584	[203]	[192]	2	hSpCas9	negative selection	155402
38264952	38264975	19	+	26472758	Jiyoye	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.2732066842939652	[124]	[77]	-2	hSpCas9	negative selection	155403
38264936	38264959	19	-	26472758	Jiyoye	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	0.9509152195005166	[141]	[206]	6	hSpCas9	negative selection	155404
38287921	38287944	19	-	26472758	Jiyoye	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	-0.1588573906804318	[264]	[178]	-1	hSpCas9	negative selection	155405
38287882	38287905	19	-	26472758	KBM7	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	0.011499829266041317	[917,726]	[526,261]	0	hSpCas9	negative selection	346520
38264952	38264975	19	+	26472758	KBM7	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.31268877448174565	[606,395]	[201,172]	-3	hSpCas9	negative selection	346521
38264936	38264959	19	-	26472758	KBM7	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	0.37967961224401225	[1062,661]	[580,460]	4	hSpCas9	negative selection	346522
38287921	38287944	19	-	26472758	KBM7	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.3828635827764687	[893,749]	[484,516]	4	hSpCas9	negative selection	346523
38287882	38287905	19	-	26472758	Raji	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	0.031032649243484645	[290]	[68]	0	hSpCas9	negative selection	537638
38264952	38264975	19	+	26472758	Raji	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.6702240432899527	[335]	[48]	-5	hSpCas9	negative selection	537639
38264936	38264959	19	-	26472758	Raji	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	0.17449773123213652	[377]	[98]	1	hSpCas9	negative selection	537640
38287921	38287944	19	-	26472758	Raji	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	1.195792509595365	[268]	[142]	9	hSpCas9	negative selection	537641
38287882	38287905	19	-	26472758	K562	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	-0.3589223023695637	[552]	[363]	-2	hSpCas9	negative selection	728756
38264952	38264975	19	+	26472758	K562	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-1.762998743896036	[389]	[96]	-7	hSpCas9	negative selection	728757
38264936	38264959	19	-	26472758	K562	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	0.18657465309416232	[686]	[659]	1	hSpCas9	negative selection	728758
38287921	38287944	19	-	26472758	K562	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	-0.40163837030154875	[614]	[392]	-3	hSpCas9	negative selection	728759
38264922	38264945	19	-	26627737	DLD1	viability	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	-0.014674117217694072	[180]	[49,77,42]	0	hSpCas9	negative selection	804488
38283669	38283692	19	-	26627737	DLD1	viability	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.02916791872872354	[646]	[371,146,111]	0	hSpCas9	negative selection	804489
38287914	38287937	19	+	26627737	DLD1	viability	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	-0.272432366218899	[545]	[244,136,54]	-3	hSpCas9	negative selection	804490
38289126	38289149	19	+	26627737	DLD1	viability	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-1.3199460628084283	[175]	[28,15,20]	-8	hSpCas9	negative selection	804491
38264922	38264945	19	-	26627737	GBM cells	viability after 5 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.2701696821366161	[183]	[113,123]	4	hSpCas9	negative selection	886803
38283669	38283692	19	-	26627737	GBM cells	viability after 5 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.156543476278675	[311]	[187,184]	2	hSpCas9	negative selection	886804
38287914	38287937	19	+	26627737	GBM cells	viability after 5 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.4415655707488772	[172]	[125,125]	6	hSpCas9	negative selection	886805
38289126	38289149	19	+	26627737	GBM cells	viability after 5 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-0.16038330879808638	[148]	[70,71]	-2	hSpCas9	negative selection	886806
38264922	38264945	19	-	26627737	GBM cells	viability after 13 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.21230937657414425	[183]	[129,103]	2	hSpCas9	negative selection	969118
38283669	38283692	19	-	26627737	GBM cells	viability after 13 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	-0.23123933027184804	[311]	[157,132]	-3	hSpCas9	negative selection	969119
38287914	38287937	19	+	26627737	GBM cells	viability after 13 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.46395548458294056	[172]	[177,89]	6	hSpCas9	negative selection	969120
38289126	38289149	19	+	26627737	GBM cells	viability after 13 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-0.4641642292562195	[148]	[94,28]	-5	hSpCas9	negative selection	969121
38264922	38264945	19	-	26627737	GBM cells	viability after 21 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.3692648463785514	[183]	[137,120]	4	hSpCas9	negative selection	1051433
38283669	38283692	19	-	26627737	GBM cells	viability after 21 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	-0.2755424443685911	[311]	[150,129]	-3	hSpCas9	negative selection	1051434
38287914	38287937	19	+	26627737	GBM cells	viability after 21 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	-0.18399812349922817	[172]	[88,76]	-2	hSpCas9	negative selection	1051435
38289126	38289149	19	+	26627737	GBM cells	viability after 21 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	0.03687653120456669	[148]	[81,83]	0	hSpCas9	negative selection	1051436
38264922	38264945	19	-	26627737	RPE1	viability after 9 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.8792731323139651	[309]	[157,204]	5	hSpCas9	negative selection	1133748
38283669	38283692	19	-	26627737	RPE1	viability after 9 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.7639146762133084	[352]	[112,283]	5	hSpCas9	negative selection	1133749
38287914	38287937	19	+	26627737	RPE1	viability after 9 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	-0.24224688406008188	[1668]	[346,563]	-2	hSpCas9	negative selection	1133750
38289126	38289149	19	+	26627737	RPE1	viability after 9 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	0.43537513284519425	[275]	[101,135]	3	hSpCas9	negative selection	1133751
38264922	38264945	19	-	26627737	RPE1	viability after 12 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	1.3140712295001689	[309]	[192,221]	7	hSpCas9	negative selection	1216063
38283669	38283692	19	-	26627737	RPE1	viability after 12 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	1.0731418650864313	[352]	[149,251]	6	hSpCas9	negative selection	1216064
38287914	38287937	19	+	26627737	RPE1	viability after 12 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	-0.1203565559568115	[1668]	[463,357]	-1	hSpCas9	negative selection	1216065
38289126	38289149	19	+	26627737	RPE1	viability after 12 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	0.15165905944490876	[275]	[94,68]	1	hSpCas9	negative selection	1216066
38264922	38264945	19	-	26627737	RPE1	viability after 15 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	1.113675150068496	[309]	[174,203]	6	hSpCas9	negative selection	1298378
38283669	38283692	19	-	26627737	RPE1	viability after 15 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.6758417403503942	[352]	[101,214]	4	hSpCas9	negative selection	1298379
38287914	38287937	19	+	26627737	RPE1	viability after 15 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	-0.3464688589920423	[1668]	[380,361]	-2	hSpCas9	negative selection	1298380
38289126	38289149	19	+	26627737	RPE1	viability after 15 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	1.1675841972675562	[275]	[181,168]	6	hSpCas9	negative selection	1298381
38264922	38264945	19	-	26627737	RPE1	viability after 18 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	1.20266690167771	[309]	[164,221]	7	hSpCas9	negative selection	1380693
38283669	38283692	19	-	26627737	RPE1	viability after 18 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.7743266224878006	[352]	[131,195]	5	hSpCas9	negative selection	1380694
38287914	38287937	19	+	26627737	RPE1	viability after 18 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	-0.6249008160198797	[1668]	[235,351]	-4	hSpCas9	negative selection	1380695
38289126	38289149	19	+	26627737	RPE1	viability after 18 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	1.0192315414602757	[275]	[149,151]	6	hSpCas9	negative selection	1380696
38264922	38264945	19	-	26627737	HeLa	viability after 8 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.16004984050700538	[376]	[126,219,189]	1	hSpCas9	negative selection	1463008
38283669	38283692	19	-	26627737	HeLa	viability after 8 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.5326257804834597	[380]	[247,199,270]	5	hSpCas9	negative selection	1463009
38287914	38287937	19	+	26627737	HeLa	viability after 8 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.28356167933273335	[316]	[191,163,153]	2	hSpCas9	negative selection	1463010
38289126	38289149	19	+	26627737	HeLa	viability after 8 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-0.27867828471262757	[301]	[171,117,52]	-3	hSpCas9	negative selection	1463011
38264922	38264945	19	-	26627737	HeLa	viability after 12 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.13861318007424184	[376]	[269,146,102]	1	hSpCas9	negative selection	1545323
38283669	38283692	19	-	26627737	HeLa	viability after 12 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.5645184801990543	[380]	[260,245,190]	5	hSpCas9	negative selection	1545324
38287914	38287937	19	+	26627737	HeLa	viability after 12 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.8958909871887961	[316]	[277,189,269]	7	hSpCas9	negative selection	1545325
38289126	38289149	19	+	26627737	HeLa	viability after 12 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-0.9184816669863598	[301]	[90,35,74]	-7	hSpCas9	negative selection	1545326
38264922	38264945	19	-	26627737	HeLa	viability after 15 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.02350804415501502	[376]	[210,139,112]	0	hSpCas9	negative selection	1627638
38283669	38283692	19	-	26627737	HeLa	viability after 15 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.6934712576857508	[380]	[249,281,217]	5	hSpCas9	negative selection	1627639
38287914	38287937	19	+	26627737	HeLa	viability after 15 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.8990452880902411	[316]	[277,232,207]	6	hSpCas9	negative selection	1627640
38289126	38289149	19	+	26627737	HeLa	viability after 15 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-0.6730452108387628	[301]	[109,102,12]	-5	hSpCas9	negative selection	1627641
38264922	38264945	19	-	26627737	HeLa	viability after 18 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.089883721583698	[376]	[150,121,112]	0	hSpCas9	negative selection	1709953
38283669	38283692	19	-	26627737	HeLa	viability after 18 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.736741978895474	[380]	[174,242,217]	6	hSpCas9	negative selection	1709954
38287914	38287937	19	+	26627737	HeLa	viability after 18 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.8758285618582136	[316]	[178,192,207]	6	hSpCas9	negative selection	1709955
38289126	38289149	19	+	26627737	HeLa	viability after 18 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-0.6733891294565089	[301]	[73,84,12]	-5	hSpCas9	negative selection	1709956
38264922	38264945	19	-	26627737	HCT116	viability after 6 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.2955870337604386	[271]	[85,33]	1	hSpCas9	negative selection	1792268
38283669	38283692	19	-	26627737	HCT116	viability after 6 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.6944466450848146	[513]	[356,5]	4	hSpCas9	negative selection	1792269
38287914	38287937	19	+	26627737	HCT116	viability after 6 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.03056977416916759	[655]	[221,40]	0	hSpCas9	negative selection	1792270
38289126	38289149	19	+	26627737	HCT116	viability after 6 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-1.8463151366850727	[466]	[51,2]	-8	hSpCas9	negative selection	1792271
38264922	38264945	19	-	26627737	HCT116	viability after 8 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	-0.5672888014297052	[220]	[63,80,100]	-6	hSpCas9	negative selection	1874583
38283669	38283692	19	-	26627737	HCT116	viability after 8 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	-0.038948820549237484	[386]	[226,266,129]	0	hSpCas9	negative selection	1874584
38287914	38287937	19	+	26627737	HCT116	viability after 8 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.28744726584482755	[361]	[354,187,189]	3	hSpCas9	negative selection	1874585
38289126	38289149	19	+	26627737	HCT116	viability after 8 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-0.0038623495104103678	[221]	[114,138,111]	0	hSpCas9	negative selection	1874586
38264922	38264945	19	-	26627737	HCT116	viability after 9 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.7666832926886576	[271]	[203,59]	5	hSpCas9	negative selection	1956898
38283669	38283692	19	-	26627737	HCT116	viability after 9 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.4261728777202574	[513]	[251,130]	3	hSpCas9	negative selection	1956899
38287914	38287937	19	+	26627737	HCT116	viability after 9 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	-0.4772435054101248	[655]	[136,116]	-3	hSpCas9	negative selection	1956900
38289126	38289149	19	+	26627737	HCT116	viability after 9 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-0.03229752760397331	[466]	[50,177]	0	hSpCas9	negative selection	1956901
38264922	38264945	19	-	26627737	HCT116	viability after 12 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	-0.19522016219457627	[220]	[79,133,92]	-2	hSpCas9	negative selection	2039213
38283669	38283692	19	-	26627737	HCT116	viability after 12 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.23662379266766803	[386]	[224,273,221]	2	hSpCas9	negative selection	2039214
38287914	38287937	19	+	26627737	HCT116	viability after 12 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.4773501021949553	[361]	[323,208,254]	4	hSpCas9	negative selection	2039215
38289126	38289149	19	+	26627737	HCT116	viability after 12 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	0.07204393334747683	[221]	[62,115,193]	0	hSpCas9	negative selection	2039216
38264922	38264945	19	-	26627737	HCT116	viability after 15 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	-0.04301404644114537	[220]	[228,75,77]	0	hSpCas9	negative selection	2121528
38283669	38283692	19	-	26627737	HCT116	viability after 15 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.7150462108535895	[386]	[450,289,363]	6	hSpCas9	negative selection	2121529
38287914	38287937	19	+	26627737	HCT116	viability after 15 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.22916009456956138	[361]	[345,194,202]	2	hSpCas9	negative selection	2121530
38289126	38289149	19	+	26627737	HCT116	viability after 15 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-0.08065585029118794	[221]	[121,130,108]	-1	hSpCas9	negative selection	2121531
38264922	38264945	19	-	26627737	HCT116	viability after 18 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	-0.8162452038172737	[220]	[52,46,83]	-6	hSpCas9	negative selection	2203843
38283669	38283692	19	-	26627737	HCT116	viability after 18 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.31628092023767623	[386]	[294,154,254]	2	hSpCas9	negative selection	2203844
38287914	38287937	19	+	26627737	HCT116	viability after 18 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	-0.2533566539801362	[361]	[115,94,236]	-2	hSpCas9	negative selection	2203845
38289126	38289149	19	+	26627737	HCT116	viability after 18 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	0.12593537679170114	[221]	[108,131,108]	1	hSpCas9	negative selection	2203846
38264328	38264351	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGGGTGGCAGGTGCTCAGCGGG	SPINT2	ENSG00000167642	0.8788349143054024	[22,99]	[6,44]	3	dCas9-VP64	positive selection	2404872
38264303	38264326	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTTGGGCTTGGTGACGACGTCGG	SPINT2	ENSG00000167642	-0.5327536236068764	[144,90]	[23,9]	-3	dCas9-VP64	positive selection	2404873
38264278	38264301	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGGCCTTCGCTCTAGGACTGG	SPINT2	ENSG00000167642	1.3046495482193157	[28,16]	[10,12]	5	dCas9-VP64	positive selection	2404874
38258539	38258562	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATCGCTTGAACCTGGGAGGGGG	SPINT2	ENSG00000167642	0.7552978455787054	[33,39]	[12,13]	3	dCas9-VP64	positive selection	2413239
38256750	38256773	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATGAGTGAATGAATGAACGAAGG	SPINT2	ENSG00000167642	2.481611665782585	[268,186]	[85,489]	8	dCas9-VP64	positive selection	2415163
38256675	38256698	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGGCGGGGTGGGGGGCTGTTGG	SPINT2	ENSG00000167642	4.665891432357728	[47,65]	[349,292]	9	dCas9-VP64	positive selection	2415164
38256710	38256733	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCGCTGTCGCTGTAGAAGG	SPINT2	ENSG00000167642	-0.3752350623054912	[12,40]	[4,2]	-2	dCas9-VP64	positive selection	2415165
38261645	38261668	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCGTGTTAGCCCAG	SPINT2	ENSG00000167642	0.853016361217498	[78,47]	[31,16]	3	dCas9-VP64	positive selection	2418321
38281602	38281625	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGGCTGAGGCAGGAGAACAG	SPINT2	ENSG00000167642	-0.8896445471743792	[26,0]	[0,0]	-5	dCas9-VP64	positive selection	2422186
38249441	38249464	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGTCAGATCACCTGAGGTCAGG	SPINT2	ENSG00000167642	1.9587821222707034	[130,16]	[18,108]	7	dCas9-VP64	positive selection	2463608
38264328	38264351	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGGGTGGCAGGTGCTCAGCGGG	SPINT2	ENSG00000167642	1.6083849060326023	[25,19]	[33,11]	8	dCas9-VP64	positive selection	2500127
38264303	38264326	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTTGGGCTTGGTGACGACGTCGG	SPINT2	ENSG00000167642	1.0327440782004653	[223,117]	[65,160]	6	dCas9-VP64	positive selection	2500128
38264278	38264301	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGGCCTTCGCTCTAGGACTGG	SPINT2	ENSG00000167642	-0.12159258767322889	[58,105]	[12,34]	-1	dCas9-VP64	positive selection	2500129
38258539	38258562	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATCGCTTGAACCTGGGAGGGGG	SPINT2	ENSG00000167642	1.0802526276452251	[21,53]	[11,38]	7	dCas9-VP64	positive selection	2508494
38256750	38256773	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATGAGTGAATGAATGAACGAAGG	SPINT2	ENSG00000167642	-1.2161714270350918	[443,339]	[72,37]	-9	dCas9-VP64	positive selection	2510418
38256675	38256698	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGGCGGGGTGGGGGGCTGTTGG	SPINT2	ENSG00000167642	-0.15651659095341808	[35,75]	[17,13]	-1	dCas9-VP64	positive selection	2510419
38256710	38256733	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCGCTGTCGCTGTAGAAGG	SPINT2	ENSG00000167642	-1.1988311706262271	[132,6]	[15,2]	-9	dCas9-VP64	positive selection	2510420
38261645	38261668	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCGTGTTAGCCCAG	SPINT2	ENSG00000167642	1.9224239682243596	[76,41]	[141,10]	8	dCas9-VP64	positive selection	2513576
38281602	38281625	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGGCTGAGGCAGGAGAACAG	SPINT2	ENSG00000167642	0.4958448470370793	[21,20]	[10,7]	4	dCas9-VP64	positive selection	2517441
38249441	38249464	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGTCAGATCACCTGAGGTCAGG	SPINT2	ENSG00000167642	1.9179472110814313	[69,68]	[20,145]	8	dCas9-VP64	positive selection	2558863
38264953	38264976	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.02449868145803294	[3,3]	[3,1]	0	hSpCas9	positive selection	3023420
38287882	38287905	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	-0.25968704419435445	[2,2]	[2,1]	-4	hSpCas9	positive selection	3023421
38287896	38287919	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCCACCAGCAGGAATGCAGCGG	SPINT2	ENSG00000167642	0.07339505183842154	[3,3]	[3,3]	1	hSpCas9	positive selection	3023422
38287866	38287889	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCCCTTGCAGAGAATGCCACGG	SPINT2	ENSG00000167642	-0.22532290727771964	[3,3]	[1,2]	-3	hSpCas9	positive selection	3023423
38264953	38264976	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.3292734674554784	[3,3]	[2,0]	-5	hSpCas9	positive selection	3091278
38287882	38287905	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	0.08304781540151998	[2,2]	[4,0]	1	hSpCas9	positive selection	3091279
38287896	38287919	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCCACCAGCAGGAATGCAGCGG	SPINT2	ENSG00000167642	0.3118380235240799	[3,3]	[3,3]	5	hSpCas9	positive selection	3091280
38287866	38287889	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCCCTTGCAGAGAATGCCACGG	SPINT2	ENSG00000167642	0.2432672930701269	[3,3]	[2,3]	4	hSpCas9	positive selection	3091281
38287897	38287920		-	24336571	A375	resistance to PLX after 7 days	ATCCGCTGCATTCCTGCTGGTGG	SPINT2	ENSG00000167642	-0.0100009829092782	[31,30]	[30,30]	0	hSpCas9	positive selection	3147168
38287921	38287944		-	24336571	A375	resistance to PLX after 7 days	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.2402052850711111	[13,12]	[14,15]	7	hSpCas9	positive selection	3147169
38287897	38287920		-	24336571	A375	resistance to PLX after 14 days	ATCCGCTGCATTCCTGCTGGTGG	SPINT2	ENSG00000167642	-0.7909834291717326	[29,27]	[7,5]	-8	hSpCas9	positive selection	3204961
38287921	38287944		-	24336571	A375	resistance to PLX after 14 days	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.28767476365846234	[10,9]	[5,4]	3	hSpCas9	positive selection	3204962
38287897	38287920		-	24336571	A375	viability after 7 days	ATCCGCTGCATTCCTGCTGGTGG	SPINT2	ENSG00000167642	0.05552759133349694	[31]	[31,30]	0	hSpCas9	negative selection	3262754
38287921	38287944		-	24336571	A375	viability after 7 days	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	-0.5088481655699818	[19]	[13,12]	-6	hSpCas9	negative selection	3262755
38287897	38287920		-	24336571	A375	viability after 14 days	ATCCGCTGCATTCCTGCTGGTGG	SPINT2	ENSG00000167642	-0.07102816421192437	[31]	[29,27]	-1	hSpCas9	negative selection	3320547
38287921	38287944		-	24336571	A375	viability after 14 days	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	-0.8080743358382722	[19]	[10,9]	-7	hSpCas9	negative selection	3320548
38283616	38283639	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	-0.05555674383852015	[158,158]	[0,0]	0	hSpCas9	positive selection	3394724
38264952	38264975	19	+	26780180	HT29	viability (Avana library 4 designs)	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	2.03200114338347	[]	[]	7	hSpCas9	negative selection	3462044
38287882	38287905	19	-	26780180	HT29	viability (Avana library 4 designs)	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	1.41388477924578	[]	[]	5	hSpCas9	negative selection	3462045
38287895	38287918	19	+	26780180	HT29	viability (Avana library 4 designs)	GGCCACCAGCAGGAATGCAGCGG	SPINT2	ENSG00000167642	1.59343609151744	[]	[]	6	hSpCas9	negative selection	3462046
38287865	38287888	19	+	26780180	HT29	viability (Avana library 4 designs)	TCCCCTTGCAGAGAATGCCACGG	SPINT2	ENSG00000167642	1.24767411915302	[]	[]	5	hSpCas9	negative selection	3462047
38264952	38264975	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	5.50422210847164	[]	[]	8	hSpCas9	negative selection	3563386
38287882	38287905	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	3.5337444780432	[]	[]	5	hSpCas9	negative selection	3563387
38287865	38287888	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCCCTTGCAGAGAATGCCACGG	SPINT2	ENSG00000167642	-1.47720789549094	[]	[]	-2	hSpCas9	negative selection	3563388
38287895	38287918	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCACCAGCAGGAATGCAGCGG	SPINT2	ENSG00000167642	0.28051244433057	[]	[]	0	hSpCas9	negative selection	3563389
38287914	38287937	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	3.92621636204881	[]	[]	6	hSpCas9	negative selection	3563390
38287900	38287923	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAATCCGCTGCATTCCTGCTGG	SPINT2	ENSG00000167642	2.33571733638774	[]	[]	3	hSpCas9	negative selection	3563391
38264952	38264975	19	+	26780180	A375	viability (Avana lentiGuide)	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-2.67346777182183	[]	[]	-5	hSpCas9	negative selection	3672045
38287882	38287905	19	-	26780180	A375	viability (Avana lentiGuide)	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	1.84400149210706	[]	[]	2	hSpCas9	negative selection	3672046
38287865	38287888	19	+	26780180	A375	viability (Avana lentiGuide)	TCCCCTTGCAGAGAATGCCACGG	SPINT2	ENSG00000167642	7.20467219484514	[]	[]	5	hSpCas9	negative selection	3672047
38287895	38287918	19	+	26780180	A375	viability (Avana lentiGuide)	GGCCACCAGCAGGAATGCAGCGG	SPINT2	ENSG00000167642	4.99642537995365	[]	[]	4	hSpCas9	negative selection	3672048
38287914	38287937	19	+	26780180	A375	viability (Avana lentiGuide)	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	2.85351258156459	[]	[]	3	hSpCas9	negative selection	3672049
38287900	38287923	19	-	26780180	A375	viability (Avana lentiGuide)	GGAATCCGCTGCATTCCTGCTGG	SPINT2	ENSG00000167642	2.38997024745465	[]	[]	2	hSpCas9	negative selection	3672050
38264952	38264975	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	0.11482669555963386	[4]	[4,4]	3	hSpCas9	positive selection	3780652
38287882	38287905	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	0.2245869540675361	[3]	[4,4]	6	hSpCas9	positive selection	3780653
38287865	38287888	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCCCTTGCAGAGAATGCCACGG	SPINT2	ENSG00000167642	-0.029940693008459515	[4]	[4,3]	0	hSpCas9	positive selection	3780654
38287895	38287918	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCACCAGCAGGAATGCAGCGG	SPINT2	ENSG00000167642	-0.2153046920837164	[4]	[4,3]	-3	hSpCas9	positive selection	3780655
38287914	38287937	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.2580699992779498	[4]	[5,4]	7	hSpCas9	positive selection	3780656
38287900	38287923	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAATCCGCTGCATTCCTGCTGG	SPINT2	ENSG00000167642	0.03003419791604013	[4]	[5,4]	0	hSpCas9	positive selection	3780657
38264952	38264975	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.40606769770190293	[4]	[3,1]	-5	hSpCas9	positive selection	3889259
38287882	38287905	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	-0.8849806950437663	[5]	[1,1]	-8	hSpCas9	positive selection	3889260
38287865	38287888	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCCCTTGCAGAGAATGCCACGG	SPINT2	ENSG00000167642	-0.30639581339586475	[5]	[1,4]	-4	hSpCas9	positive selection	3889261
38287895	38287918	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCACCAGCAGGAATGCAGCGG	SPINT2	ENSG00000167642	0.18557444030710538	[5]	[5,4]	4	hSpCas9	positive selection	3889262
38287914	38287937	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.33293713753089565	[4]	[5,4]	8	hSpCas9	positive selection	3889263
38287900	38287923	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAATCCGCTGCATTCCTGCTGG	SPINT2	ENSG00000167642	-0.09493472859684218	[5]	[4,4]	-1	hSpCas9	positive selection	3889264
38283616	38283639	19	+	26780180	A375	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.807382864970677	[]	[]	3	hSpCas9	negative selection	3999011
38283634	38283657	19	-	26780180	A375	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.566205034906289	[]	[]	1	hSpCas9	negative selection	3999012
38283616	38283639	19	+	26780180	HT29	viability (GeCKOv2 library)	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	1.27197138445605	[]	[]	6	hSpCas9	negative selection	4106977
38283634	38283657	19	-	26780180	HT29	viability (GeCKOv2 library)	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.80865795407674	[]	[]	3	hSpCas9	negative selection	4106978
38287897	38287920	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCCGCTGCATTCCTGCTGGTGG	SPINT2	ENSG00000167642	-0.06982743390525181	[5]	[3,2]	-2	hSpCas9	positive selection	4173335
38287921	38287944	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	-0.07170701481165134	[4]	[2,2]	-2	hSpCas9	positive selection	4173336
38287897	38287920	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCCGCTGCATTCCTGCTGGTGG	SPINT2	ENSG00000167642	0.9286720353820452	[4]	[3,4,1,4]	6	hSpCas9	positive selection	4237357
38287921	38287944	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.05783776615140712	[3]	[3,1,0,0]	0	hSpCas9	positive selection	4237358
38283634	38283657	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.28763288859988234	[4]	[4,4]	6	hSpCas9	positive selection	4300341
38283616	38283639	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.3319241724705118	[2]	[2,2]	6	hSpCas9	positive selection	4364596
38287921	38287943	19	-	27760321	OCIAML3	viability	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.6147954757230685	[536,419]	[586,545]	7	hSpCas9	negative selection	4442807
38287921	38287943	19	-	27760321	OCIAML2	viability	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.37776780851168124	[536,419]	[417,606]	5	hSpCas9	negative selection	4526270
38287921	38287943	19	-	27760321	MV411	viability	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.34110849594315606	[536,419]	[499,242]	2	hSpCas9	negative selection	4609733
38287921	38287943	19	-	27760321	HL60	viability	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	-0.12701089503287522	[536,419]	[322,389]	-1	hSpCas9	negative selection	4693196
38287921	38287943	19	-	27760321	HT1080	viability	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.20838759100094031	[419,327]	[227,110]	1	hSpCas9	negative selection	4776659
38287921	38287943	19	-	27760321	HT29	viability after 7 days	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.36847418335402005	[419,327]	[762,631,490]	5	hSpCas9	negative selection	4860122
38287921	38287943	19	-	27760321	HT29	viability after 25 days	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.4544973506626497	[419,327]	[568,587,601]	5	hSpCas9	negative selection	4943585
38287921	38287943	19	-	27760321	HT29	viability after 22 days	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	-0.08601517704108613	[419,327]	[427,436,355]	-1	hSpCas9	negative selection	5027048
38287921	38287943	19	-	27760321	HT29	viability after 19 days	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.19084849278603946	[419,327]	[517,178,759]	1	hSpCas9	negative selection	5110511
38287921	38287943	19	-	27760321	HT29	viability after 16 days	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.24030233717846897	[419,327]	[756,325,428]	2	hSpCas9	negative selection	5193974
38287921	38287943	19	-	27760321	HT29	viability after 13 days	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.16358374692012426	[419,327]	[542,432,481]	2	hSpCas9	negative selection	5277437
38287921	38287943	19	-	27760321	HT29	viability after 10 days	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.34344641844663587	[419,327]	[638,563,573]	4	hSpCas9	negative selection	5360900
38287921	38287943	19	-	27760321	MOLM13	viability	AACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.6843956494527712	[536,419]	[310,532]	5	hSpCas9	negative selection	5444363
38264585	38264608	19	+	27661255	K562	viability	GGCGACCTCCGCGCGTTGGGAGG	SPINT2	ENSG00000167642	0.3278337914512278	[523,645]	[694,489]	9	dCas9-KRAB	negative selection	5513998
38264595	38264618	19	+	27661255	K562	viability	GCGCGTTGGGAGGTGTAGCGCGG	SPINT2	ENSG00000167642	0.16975201580290009	[674,654]	[680,526]	6	dCas9-KRAB	negative selection	5513999
38264633	38264656	19	+	27661255	K562	viability	GGGCCGTTGAGTGTCGCAGGCGG	SPINT2	ENSG00000167642	-0.005496485125167538	[1017,829]	[859,633]	0	dCas9-KRAB	negative selection	5514000
38264684	38264707	19	+	27661255	K562	viability	GCATCGCGCGCCGAGAAGGCCGG	SPINT2	ENSG00000167642	0.2541540662814676	[439,567]	[579,390]	8	dCas9-KRAB	negative selection	5514001
38265003	38265026	19	+	27661255	K562	viability	GGGCCGGGCGGGTAGGCTGGAGG	SPINT2	ENSG00000167642	0.07311599239684075	[400,475]	[409,330]	2	dCas9-KRAB	negative selection	5514002
38283634	38283657	19	-	27260156	BXPC3	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.3113022905514444	[1857]	[2295,2451,2098,2834]	6	hSpCas9	negative selection	5572801
38283616	38283639	19	+	27260156	BXPC3	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.3265849509620838	[300]	[299,424,405,461]	7	hSpCas9	negative selection	5637056
38283634	38283657	19	-	27260156	A673	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.26847597087853026	[1857]	[2660,2639,2756,2682]	6	hSpCas9	negative selection	5694052
38283616	38283639	19	+	27260156	A673	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.37819610812032195	[300]	[609,409,367,510]	8	hSpCas9	negative selection	5758307
38283634	38283657	19	-	27260156	A375	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.2731398453296954	[1857]	[2428,3277,2929,2006]	4	hSpCas9	negative selection	5815303
38283616	38283639	19	+	27260156	A375	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.4788630568686144	[300]	[401,613,509,452]	7	hSpCas9	negative selection	5879558
38283634	38283657	19	-	27260156	COLO741	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.29284954591466295	[1857]	[3615,2784,2413]	6	hSpCas9	negative selection	5936554
38283616	38283639	19	+	27260156	COLO741	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.22692086766492375	[300]	[488,489,378]	5	hSpCas9	negative selection	6000809
38283634	38283657	19	-	27260156	CAL120	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.4897538373402359	[1857]	[3994,3161,2703]	7	hSpCas9	negative selection	6057805
38283616	38283639	19	+	27260156	CAL120	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.21151822847963508	[300]	[433,601,267]	3	hSpCas9	negative selection	6122060
38283634	38283657	19	-	27260156	CADOES1	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.07060206626301402	[1857]	[2013,1803,1609,1830]	1	hSpCas9	negative selection	6179056
38283616	38283639	19	+	27260156	CADOES1	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.1157845478738464	[300]	[310,364,322,210]	2	hSpCas9	negative selection	6243311
38283634	38283657	19	-	27260156	EWS502	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.22261851974498037	[1857]	[2191,2170,2319,2527]	4	hSpCas9	negative selection	6300307
38283616	38283639	19	+	27260156	EWS502	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.41771292472667476	[300]	[464,479,409,332]	7	hSpCas9	negative selection	6364562
38283634	38283657	19	-	27260156	EW8	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.0417876815453575	[1857]	[1384,1913,1343,1570]	0	hSpCas9	negative selection	6421558
38283616	38283639	19	+	27260156	EW8	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.08617085069783981	[300]	[277,213,257,286]	1	hSpCas9	negative selection	6485813
38283634	38283657	19	-	27260156	CORL105	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.07990485536943104	[1857]	[2723,1992,2559,1980]	1	hSpCas9	negative selection	6542809
38283616	38283639	19	+	27260156	CORL105	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.3145819269238128	[300]	[510,500,396,338]	6	hSpCas9	negative selection	6607064
38283634	38283657	19	-	27260156	HS294T	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.5642203788445246	[1857]	[1005,976,966,1351]	7	hSpCas9	negative selection	6664060
38283616	38283639	19	+	27260156	HS294T	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.6999103608319555	[300]	[245,222,129,141]	8	hSpCas9	negative selection	6728315
38283634	38283657	19	-	27260156	HCC44	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.40290196903213515	[1857]	[2935,1945,3132,3253]	6	hSpCas9	negative selection	6785311
38283616	38283639	19	+	27260156	HCC44	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.3460122325059371	[300]	[527,402,507,317]	5	hSpCas9	negative selection	6849566
38283634	38283657	19	-	27260156	G402	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.1329012381375605	[1857]	[2682,2873,2302,2141]	1	hSpCas9	negative selection	6906562
38283616	38283639	19	+	27260156	G402	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.5843526326827378	[300]	[603,687,536,394]	7	hSpCas9	negative selection	6970817
38283634	38283657	19	-	27260156	L33	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.4427024705460407	[1857]	[2270,1009,1539,2916]	8	hSpCas9	negative selection	7027813
38283616	38283639	19	+	27260156	L33	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.012484811744029378	[300]	[250,117,215,332]	0	hSpCas9	negative selection	7092068
38283634	38283657	19	-	27260156	K562	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.045064917129588045	[1857]	[1686,1674,1789,1648]	0	hSpCas9	negative selection	7149064
38283616	38283639	19	+	27260156	K562	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.2621431951830237	[300]	[609,221,225,248]	3	hSpCas9	negative selection	7213319
38283634	38283657	19	-	27260156	HT29	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.07787693674448648	[1857]	[2317,2737,2377,2139]	1	hSpCas9	negative selection	7270315
38283616	38283639	19	+	27260156	HT29	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.38888685063255746	[300]	[437,416,431,601]	7	hSpCas9	negative selection	7334570
38283634	38283657	19	-	27260156	MHHES1	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.20892067495232447	[1857]	[2750,3208,2407,1571]	4	hSpCas9	negative selection	7391566
38283616	38283639	19	+	27260156	MHHES1	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.4605052099908177	[300]	[502,560,341,462]	7	hSpCas9	negative selection	7455821
38283634	38283657	19	-	27260156	MEWO	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.27902553050756196	[1857]	[2134,1917,2279]	6	hSpCas9	negative selection	7512817
38283616	38283639	19	+	27260156	MEWO	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.44924079555601976	[300]	[299,381,454]	8	hSpCas9	negative selection	7577072
38283634	38283657	19	-	27260156	LNCAPCLONEFGC	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.17768838039404922	[1857]	[1687,2008,1932,1984]	2	hSpCas9	negative selection	7634068
38283616	38283639	19	+	27260156	LNCAPCLONEFGC	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.6713219509311585	[300]	[410,475,465,385]	9	hSpCas9	negative selection	7698323
38283634	38283657	19	-	27260156	PANC0327	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.22063405107220624	[1857]	[1984,1792,1890,2044]	3	hSpCas9	negative selection	7755319
38283616	38283639	19	+	27260156	PANC0327	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	-0.31942903673676026	[300]	[273,221,222,141]	-5	hSpCas9	negative selection	7819574
38283634	38283657	19	-	27260156	NCIH2009	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.31948895668327304	[1857]	[4283,3030,2607]	4	hSpCas9	negative selection	7876570
38283616	38283639	19	+	27260156	NCIH2009	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.02434851806209337	[300]	[402,399,474]	0	hSpCas9	negative selection	7940825
38283634	38283657	19	-	27260156	NCIH1373	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.1810571928659599	[1857]	[2328,2116,2154,758]	1	hSpCas9	negative selection	7997821
38283616	38283639	19	+	27260156	NCIH1373	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.5784715731639893	[300]	[669,189,705,131]	6	hSpCas9	negative selection	8062076
38283634	38283657	19	-	27260156	PATU8902	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.169885013605662	[1857]	[2454,3219,3029,2888]	1	hSpCas9	negative selection	8119072
38283616	38283639	19	+	27260156	PATU8902	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.9114980840560092	[300]	[545,972,405,1398]	8	hSpCas9	negative selection	8183327
38283634	38283657	19	-	27260156	PANC1	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.22052482890869585	[1857]	[1974,2393,2008,1240]	3	hSpCas9	negative selection	8240323
38283616	38283639	19	+	27260156	PANC1	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.354306201727946	[300]	[256,469,345,281]	6	hSpCas9	negative selection	8304578
38283634	38283657	19	-	27260156	PANC0813	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	-0.14734946299284202	[1857]	[1998,1953,1895,2028]	-2	hSpCas9	negative selection	8361574
38283616	38283639	19	+	27260156	PANC0813	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	-0.9294243500504253	[300]	[230,226,135,153]	-8	hSpCas9	negative selection	8425829
38283634	38283657	19	-	27260156	RDES	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.18190847276518185	[1857]	[2136,2199,2591,2843]	3	hSpCas9	negative selection	8482825
38283616	38283639	19	+	27260156	RDES	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.362659008084412	[300]	[326,457,354,684]	6	hSpCas9	negative selection	8547080
38283634	38283657	19	-	27260156	PC3	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.23930405427706414	[1857]	[1326,2185,3701,2293]	5	hSpCas9	negative selection	8604076
38283616	38283639	19	+	27260156	PC3	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.21429933484465236	[300]	[196,253,734,400]	5	hSpCas9	negative selection	8668331
38283634	38283657	19	-	27260156	PATU8988T	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	-0.08246330210756936	[1857]	[1341,1845,1609,2025]	-1	hSpCas9	negative selection	8725327
38283616	38283639	19	+	27260156	PATU8988T	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.19606312176866136	[300]	[221,437,312,372]	3	hSpCas9	negative selection	8789582
38283634	38283657	19	-	27260156	T47D	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.2095744320186308	[1857]	[2515,2668,2363,2447]	4	hSpCas9	negative selection	8846578
38283616	38283639	19	+	27260156	T47D	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.4285026082562037	[300]	[450,447,473,517]	8	hSpCas9	negative selection	8910833
38283634	38283657	19	-	27260156	SU8686	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.2762881571928817	[1857]	[2239,1924,2022,2852]	5	hSpCas9	negative selection	8967829
38283616	38283639	19	+	27260156	SU8686	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	-0.010039443608903409	[300]	[379,201,271,337]	0	hSpCas9	negative selection	9032084
38283634	38283657	19	-	27260156	SKES1	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.07102317639373834	[1857]	[1993,2502,1811,1577]	1	hSpCas9	negative selection	9089080
38283616	38283639	19	+	27260156	SKES1	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.22683915825889978	[300]	[333,328,399,334]	5	hSpCas9	negative selection	9153335
38283634	38283657	19	-	27260156	TOV112D	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.3054279481452371	[1857]	[2301,2976,2229,1864]	6	hSpCas9	negative selection	9210331
38283616	38283639	19	+	27260156	TOV112D	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	-0.16045097254533858	[300]	[248,435,174,257]	-3	hSpCas9	negative selection	9274586
38283634	38283657	19	-	27260156	TC71	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.27362478221596764	[1857]	[2296,2352,2453,2534]	6	hSpCas9	negative selection	9331582
38283616	38283639	19	+	27260156	TC71	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.29135648680907816	[300]	[326,361,420,474]	7	hSpCas9	negative selection	9395837
38283634	38283657	19	-	27260156	TC32	viability	TGCCCACCACCTTCGACACCAGG	SPINT2	ENSG00000167642	0.36559309965730447	[1857]	[2061,1860,2728,2474]	6	hSpCas9	negative selection	9452833
38283616	38283639	19	+	27260156	TC32	viability	TCGCGTTTCAGACTTCTGCCTGG	SPINT2	ENSG00000167642	0.5115562499072795	[300]	[316,339,593,405]	8	hSpCas9	negative selection	9517088
38264922	38264945	19	-	27869803	HPAFII	viability after 27 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	-0.6443258935200065	[139]	[39,52,NaN]	-5	hSpCas9	negative selection	9567524
38283669	38283692	19	-	27869803	HPAFII	viability after 27 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.14891989045199922	[266]	[129,176,NaN]	1	hSpCas9	negative selection	9567525
38287914	38287937	19	+	27869803	HPAFII	viability after 27 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	1.2082089202242354	[325]	[365,420,NaN]	8	hSpCas9	negative selection	9567526
38289126	38289149	19	+	27869803	HPAFII	viability after 27 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	0.05072868514856843	[100]	[60,49,NaN]	0	hSpCas9	negative selection	9567527
38264922	38264945	19	-	27869803	HPAFII	viability after 15 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	-0.5883818985606573	[139]	[141,73,NaN]	-6	hSpCas9	negative selection	9649973
38283669	38283692	19	-	27869803	HPAFII	viability after 15 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	-0.6041550850873862	[266]	[263,141,NaN]	-6	hSpCas9	negative selection	9649974
38287914	38287937	19	+	27869803	HPAFII	viability after 15 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	0.3349290557507	[325]	[444,439,NaN]	4	hSpCas9	negative selection	9649975
38289126	38289149	19	+	27869803	HPAFII	viability after 15 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-0.18587837011754038	[100]	[190,35,NaN]	-2	hSpCas9	negative selection	9649976
38264922	38264945	19	-	27869803	ASPC1	viability after 36 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.37204690505922466	[321]	[292,77,93]	4	hSpCas9	negative selection	9732422
38283669	38283692	19	-	27869803	ASPC1	viability after 36 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.1048993992079893	[781]	[81,659,147]	1	hSpCas9	negative selection	9732423
38287914	38287937	19	+	27869803	ASPC1	viability after 36 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	1.183820725872614	[731]	[609,307,769]	9	hSpCas9	negative selection	9732424
38289126	38289149	19	+	27869803	ASPC1	viability after 36 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	0.1507024746020409	[296]	[122,146,82]	1	hSpCas9	negative selection	9732425
38264922	38264945	19	-	27869803	PATU8988S	viability after 35 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	-2.4338517523391126	[301]	[26,17,NaN]	-9	hSpCas9	negative selection	9814871
38283669	38283692	19	-	27869803	PATU8988S	viability after 35 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	-1.1585477709626677	[752]	[71,199,NaN]	-8	hSpCas9	negative selection	9814872
38287914	38287937	19	+	27869803	PATU8988S	viability after 35 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	-0.8024345375028759	[724]	[133,200,NaN]	-7	hSpCas9	negative selection	9814873
38289126	38289149	19	+	27869803	PATU8988S	viability after 35 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-1.3727033442226018	[266]	[52,29,NaN]	-8	hSpCas9	negative selection	9814874
38264922	38264945	19	-	27869803	PATU8988S	viability after 31 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	-2.713400631244588	[301]	[20,14,NaN]	-9	hSpCas9	negative selection	9897320
38283669	38283692	19	-	27869803	PATU8988S	viability after 31 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	-0.507188746183176	[752]	[95,357,NaN]	-5	hSpCas9	negative selection	9897321
38287914	38287937	19	+	27869803	PATU8988S	viability after 31 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	-0.3761287603639311	[724]	[143,322,NaN]	-4	hSpCas9	negative selection	9897322
38289126	38289149	19	+	27869803	PATU8988S	viability after 31 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	-0.5627597293497995	[266]	[57,89,NaN]	-6	hSpCas9	negative selection	9897323
38264922	38264945	19	-	27869803	HPAFII	viability after 35 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	0.6970554123809982	[139]	[33,205,NaN]	4	hSpCas9	negative selection	9979769
38283669	38283692	19	-	27869803	HPAFII	viability after 35 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.15979736063420008	[266]	[150,150,NaN]	1	hSpCas9	negative selection	9979770
38287914	38287937	19	+	27869803	HPAFII	viability after 35 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	1.7872578344993544	[325]	[309,861,NaN]	9	hSpCas9	negative selection	9979771
38289126	38289149	19	+	27869803	HPAFII	viability after 35 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	0.19925309540531044	[100]	[53,63,NaN]	1	hSpCas9	negative selection	9979772
38264922	38264945	19	-	27869803	HPAFII	viability after 31 days	CCAGCAGGGCGAGAAACGCCCGG	SPINT2	ENSG00000167642	-0.12913899613589097	[139]	[45,99,NaN]	-1	hSpCas9	negative selection	10062218
38283669	38283692	19	-	27869803	HPAFII	viability after 31 days	ATTGTACCACCACCTAGGCATGG	SPINT2	ENSG00000167642	0.3477822628311685	[266]	[194,185,NaN]	2	hSpCas9	negative selection	10062219
38287914	38287937	19	+	27869803	HPAFII	viability after 31 days	GCGGATTCCTCTGTCCCAAGTGG	SPINT2	ENSG00000167642	1.5760406495514174	[325]	[399,703,NaN]	9	hSpCas9	negative selection	10062220
38289126	38289149	19	+	27869803	HPAFII	viability after 31 days	TTTGTGTTTCAGCTCCCAGAAGG	SPINT2	ENSG00000167642	0.5202164062108676	[100]	[98,61,NaN]	4	hSpCas9	negative selection	10062221
38287882	38287905	19	-	28162770	P31FUJ	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	-0.3595593467003174	[320]	[293]	-3	hSpCas9	negative selection	10242151
38264952	38264975	19	+	28162770	P31FUJ	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-1.4572961483961142	[457]	[195]	-7	hSpCas9	negative selection	10242152
38264936	38264959	19	-	28162770	P31FUJ	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	-0.7038737386075504	[279]	[201]	-5	hSpCas9	negative selection	10242153
38287921	38287944	19	-	28162770	P31FUJ	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	-0.019320836985326606	[231]	[268]	0	hSpCas9	negative selection	10242154
38287882	38287905	19	-	28162770	TF1	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10411517
38264952	38264975	19	+	28162770	TF1	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10411518
38264936	38264959	19	-	28162770	TF1	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	NaN	[NaN]	[139]	1	hSpCas9	negative selection	10411519
38287921	38287944	19	-	28162770	TF1	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10411520
38287882	38287905	19	-	28162770	SKM1	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	-0.42670041680442367	[91]	[120]	-4	hSpCas9	negative selection	10580883
38264952	38264975	19	+	28162770	SKM1	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.6432958110374833	[90]	[102]	-5	hSpCas9	negative selection	10580884
38264936	38264959	19	-	28162770	SKM1	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	0.08607581253695518	[80]	[151]	0	hSpCas9	negative selection	10580885
38287921	38287944	19	-	28162770	SKM1	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.1779983019779945	[69]	[139]	1	hSpCas9	negative selection	10580886
38287882	38287905	19	-	28162770	SKM1	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	-0.42670041680442367	[91]	[120]	-4	hSpCas9	negative selection	10750249
38264952	38264975	19	+	28162770	SKM1	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.6432958110374833	[90]	[102]	-5	hSpCas9	negative selection	10750250
38264936	38264959	19	-	28162770	SKM1	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	0.08607581253695518	[80]	[151]	0	hSpCas9	negative selection	10750251
38287921	38287944	19	-	28162770	SKM1	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.1779983019779945	[69]	[139]	1	hSpCas9	negative selection	10750252
38287882	38287905	19	-	28162770	PL21	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	1.3663124810705252	[384]	[431]	9	hSpCas9	negative selection	10919615
38264952	38264975	19	+	28162770	PL21	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.07919660367357423	[266]	[109]	0	hSpCas9	negative selection	10919616
38264936	38264959	19	-	28162770	PL21	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	0.508261909851652	[314]	[194]	4	hSpCas9	negative selection	10919617
38287921	38287944	19	-	28162770	PL21	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.8916947489655798	[212]	[171]	7	hSpCas9	negative selection	10919618
38287882	38287905	19	-	28162770	P31FUJ	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	-0.3595593467003174	[320]	[293]	-3	hSpCas9	negative selection	11088981
38264952	38264975	19	+	28162770	P31FUJ	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-1.4572961483961142	[457]	[195]	-7	hSpCas9	negative selection	11088982
38264936	38264959	19	-	28162770	P31FUJ	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	-0.7038737386075504	[279]	[201]	-5	hSpCas9	negative selection	11088983
38287921	38287944	19	-	28162770	P31FUJ	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	-0.019320836985326606	[231]	[268]	0	hSpCas9	negative selection	11088984
38287882	38287905	19	-	28162770	OCIAML5	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	0.029970091781713344	[120]	[222]	0	hSpCas9	negative selection	11258347
38264952	38264975	19	+	28162770	OCIAML5	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.9353220745133491	[213]	[201]	-5	hSpCas9	negative selection	11258348
38264936	38264959	19	-	28162770	OCIAML5	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	-0.00945286100595033	[178]	[320]	0	hSpCas9	negative selection	11258349
38287921	38287944	19	-	28162770	OCIAML5	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.2954906175498609	[129]	[287]	2	hSpCas9	negative selection	11258350
38287882	38287905	19	-	28162770	EOL1	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	0.14902050334802985	[593]	[346]	1	hSpCas9	negative selection	11427713
38264952	38264975	19	+	28162770	EOL1	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.4755750536970262	[416]	[157]	-4	hSpCas9	negative selection	11427714
38264936	38264959	19	-	28162770	EOL1	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	0.043488844294042095	[511]	[277]	0	hSpCas9	negative selection	11427715
38287921	38287944	19	-	28162770	EOL1	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.005771566844507414	[517]	[273]	0	hSpCas9	negative selection	11427716
38287882	38287905	19	-	28162770	MOLM13	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	-0.09999960581763578	[377]	[254]	0	hSpCas9	negative selection	11597079
38264952	38264975	19	+	28162770	MOLM13	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.8031378150427455	[361]	[149]	-4	hSpCas9	negative selection	11597080
38264936	38264959	19	-	28162770	MOLM13	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	0.6951420939715613	[380]	[445]	5	hSpCas9	negative selection	11597081
38287921	38287944	19	-	28162770	MOLM13	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.718378534059259	[384]	[457]	5	hSpCas9	negative selection	11597082
38287882	38287905	19	-	28162770	HEL	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	-0.8090572172886046	[423]	[154]	-5	hSpCas9	negative selection	11766445
38264952	38264975	19	+	28162770	HEL	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-1.0107034066035658	[301]	[95]	-6	hSpCas9	negative selection	11766446
38264936	38264959	19	-	28162770	HEL	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	0.6828162713756922	[425]	[437]	6	hSpCas9	negative selection	11766447
38287921	38287944	19	-	28162770	HEL	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.03096350014523419	[352]	[230]	0	hSpCas9	negative selection	11766448
38287882	38287905	19	-	28162770	MV411	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	-0.6609952096341486	[350]	[186]	-5	hSpCas9	negative selection	11935811
38264952	38264975	19	+	28162770	MV411	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.9632730655060372	[286]	[123]	-6	hSpCas9	negative selection	11935812
38264936	38264959	19	-	28162770	MV411	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	-0.16918794539926063	[302]	[226]	-1	hSpCas9	negative selection	11935813
38287921	38287944	19	-	28162770	MV411	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.8324000515039316	[219]	[329]	7	hSpCas9	negative selection	11935814
38287882	38287905	19	-	28162770	MONOMAC1	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	0.9605044299269262	[233]	[521]	8	hSpCas9	negative selection	12105177
38264952	38264975	19	+	28162770	MONOMAC1	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	0.07130159063416752	[180]	[217]	0	hSpCas9	negative selection	12105178
38264936	38264959	19	-	28162770	MONOMAC1	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	-0.34542868695222473	[265]	[239]	-3	hSpCas9	negative selection	12105179
38287921	38287944	19	-	28162770	MONOMAC1	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	-0.05081610620850985	[149]	[165]	0	hSpCas9	negative selection	12105180
38287882	38287905	19	-	28162770	OCIAML2	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	-0.5801083020406541	[64]	[240]	-4	hSpCas9	negative selection	12274543
38264952	38264975	19	+	28162770	OCIAML2	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.3431400901202454	[45]	[200]	-3	hSpCas9	negative selection	12274544
38264936	38264959	19	-	28162770	OCIAML2	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	-0.10917336616816131	[71]	[369]	-1	hSpCas9	negative selection	12274545
38287921	38287944	19	-	28162770	OCIAML2	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	0.0780691314922235	[46]	[274]	0	hSpCas9	negative selection	12274546
38287882	38287905	19	-	28162770	OCIAML3	viability	GCTGGTGGCCAGGTCACCCGTGG	SPINT2	ENSG00000167642	1.0395648046216144	[106]	[663]	8	hSpCas9	negative selection	12443909
38264952	38264975	19	+	28162770	OCIAML3	viability	GCTCCTCTCTGGGGTCCTGGCGG	SPINT2	ENSG00000167642	-0.10215454399448842	[95]	[269]	-1	hSpCas9	negative selection	12443910
38264936	38264959	19	-	28162770	OCIAML3	viability	GAGGAGCAGCGATCCCAGCAGGG	SPINT2	ENSG00000167642	0.3810747274715075	[72]	[286]	3	hSpCas9	negative selection	12443911
38287921	38287944	19	-	28162770	OCIAML3	viability	GAACCTACCACTTGGGACAGAGG	SPINT2	ENSG00000167642	-0.14420472288464292	[81]	[223]	-1	hSpCas9	negative selection	12443912