Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:391253
• Symbol:SPINT4
• Description:serine peptidase inhibitor, Kunitz type 4

DataSource: http://genomecrispr.dkfz.de/#!/results/SPINT4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
45722461	45722484	20	+	26472758	Jiyoye	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	0.9242338177252262	[115]	[165]	6	hSpCas9	negative selection	155416
45723979	45724002	20	-	26472758	Jiyoye	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.4600272637716083	[133]	[138]	3	hSpCas9	negative selection	155417
45722419	45722442	20	+	26472758	Jiyoye	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.8887686500673295	[322]	[450]	6	hSpCas9	negative selection	155418
45722378	45722401	20	-	26472758	Jiyoye	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.23838770376525953	[316]	[281]	1	hSpCas9	negative selection	155419
45722365	45722388	20	+	26472758	Jiyoye	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	0.7120299630342943	[16]	[20]	5	hSpCas9	negative selection	155420
45723872	45723895	20	+	26472758	Jiyoye	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.24526855495948618	[470]	[420]	1	hSpCas9	negative selection	155421
45722461	45722484	20	+	26472758	KBM7	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	0.8867917067449644	[667,502]	[481,523]	8	hSpCas9	negative selection	346534
45723979	45724002	20	-	26472758	KBM7	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.7092345387495058	[766,536]	[671,335]	7	hSpCas9	negative selection	346535
45722419	45722442	20	+	26472758	KBM7	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.42904710319564954	[1473,1028]	[881,691]	4	hSpCas9	negative selection	346536
45722378	45722401	20	-	26472758	KBM7	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.24224258690553113	[1211,768]	[692,404]	2	hSpCas9	negative selection	346537
45722365	45722388	20	+	26472758	KBM7	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	1.4488508509952605	[37,80]	[49,105]	9	hSpCas9	negative selection	346538
45723872	45723895	20	+	26472758	KBM7	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.40241362298601	[1643,1853]	[1119,1079]	4	hSpCas9	negative selection	346539
45722461	45722484	20	+	26472758	Raji	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	0.7587190580141097	[353]	[138]	7	hSpCas9	negative selection	537652
45723979	45724002	20	-	26472758	Raji	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.7479807350675742	[194]	[75]	7	hSpCas9	negative selection	537653
45722419	45722442	20	+	26472758	Raji	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.24377200428954682	[705]	[193]	2	hSpCas9	negative selection	537654
45722378	45722401	20	-	26472758	Raji	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.5685694954563332	[522]	[179]	5	hSpCas9	negative selection	537655
45722365	45722388	20	+	26472758	Raji	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	0.8146017861457535	[48]	[19]	7	hSpCas9	negative selection	537656
45723872	45723895	20	+	26472758	Raji	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.5781304672387311	[1015]	[351]	5	hSpCas9	negative selection	537657
45722461	45722484	20	+	26472758	K562	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	-0.029503994310083048	[531]	[439]	0	hSpCas9	negative selection	728770
45723979	45724002	20	-	26472758	K562	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.2900613932221592	[559]	[577]	2	hSpCas9	negative selection	728771
45722419	45722442	20	+	26472758	K562	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.44968588997794856	[1137]	[1311]	3	hSpCas9	negative selection	728772
45722378	45722401	20	-	26472758	K562	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	-0.14044062294737214	[819]	[627]	-1	hSpCas9	negative selection	728773
45722365	45722388	20	+	26472758	K562	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	0.8477597577024576	[51]	[78]	7	hSpCas9	negative selection	728774
45723872	45723895	20	+	26472758	K562	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.6662181176541833	[1489]	[1995]	5	hSpCas9	negative selection	728775
45722364	45722387	20	+	26627737	DLD1	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.8277762336728753	[634]	[308,391,356]	7	hSpCas9	negative selection	814809
45722364	45722387	20	+	26627737	GBM cells	viability after 5 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.181798056578501	[396]	[208,273]	3	hSpCas9	negative selection	897124
45722364	45722387	20	+	26627737	GBM cells	viability after 13 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.08506542903715464	[396]	[308,162]	1	hSpCas9	negative selection	979439
45722364	45722387	20	+	26627737	GBM cells	viability after 21 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	-0.5564739839428253	[396]	[142,149]	-5	hSpCas9	negative selection	1061754
45722364	45722387	20	+	26627737	RPE1	viability after 9 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.595234890041712	[1166]	[213,987]	4	hSpCas9	negative selection	1144069
45722364	45722387	20	+	26627737	RPE1	viability after 12 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.8154495097758448	[1166]	[288,829]	5	hSpCas9	negative selection	1226384
45722364	45722387	20	+	26627737	RPE1	viability after 15 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.5484513588360828	[1166]	[296,661]	3	hSpCas9	negative selection	1308699
45722364	45722387	20	+	26627737	RPE1	viability after 18 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.4651648809595933	[1166]	[252,628]	3	hSpCas9	negative selection	1391014
45722364	45722387	20	+	26627737	HeLa	viability after 8 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.27511152506695946	[581]	[297,201,409]	2	hSpCas9	negative selection	1473329
45722364	45722387	20	+	26627737	HeLa	viability after 12 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.3629152699588518	[581]	[356,151,436]	3	hSpCas9	negative selection	1555644
45722364	45722387	20	+	26627737	HeLa	viability after 15 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.751890321970639	[581]	[291,221,707]	6	hSpCas9	negative selection	1637959
45722364	45722387	20	+	26627737	HeLa	viability after 18 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.7766234582157796	[581]	[205,187,707]	6	hSpCas9	negative selection	1720274
45722364	45722387	20	+	26627737	HCT116	viability after 6 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.20850071791304597	[867]	[254,103]	1	hSpCas9	negative selection	1802589
45722364	45722387	20	+	26627737	HCT116	viability after 8 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.7810771635611571	[420]	[351,436,405]	7	hSpCas9	negative selection	1884904
45722364	45722387	20	+	26627737	HCT116	viability after 9 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.1576350167673108	[867]	[262,254]	1	hSpCas9	negative selection	1967219
45722364	45722387	20	+	26627737	HCT116	viability after 12 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.3525014908964062	[420]	[219,408,226]	3	hSpCas9	negative selection	2049534
45722364	45722387	20	+	26627737	HCT116	viability after 15 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.4540273977488914	[420]	[370,424,203]	4	hSpCas9	negative selection	2131849
45722364	45722387	20	+	26627737	HCT116	viability after 18 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	-0.024771440446132664	[420]	[204,156,242]	0	hSpCas9	negative selection	2214164
45723882	45723905	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAATTCATGTCCAATTTGCAGGG	SPINT4	ENSG00000149651	0.48203411503117016	[3,3]	[3,5]	8	hSpCas9	positive selection	3023428
45722426	45722449	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTAACACCACCCAATAACAGGG	SPINT4	ENSG00000149651	0.4031723682564515	[3,3]	[5,3]	8	hSpCas9	positive selection	3023429
45722437	45722460	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	0.4349277683344909	[5,5]	[5,6]	8	hSpCas9	positive selection	3023430
45722420	45722443	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.39321547878392266	[3,3]	[3,4]	7	hSpCas9	positive selection	3023431
45723882	45723905	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAATTCATGTCCAATTTGCAGGG	SPINT4	ENSG00000149651	0.39989288740254636	[3,3]	[5,1]	7	hSpCas9	positive selection	3091286
45722426	45722449	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTAACACCACCCAATAACAGGG	SPINT4	ENSG00000149651	-0.12402928303393468	[3,3]	[4,0]	-2	hSpCas9	positive selection	3091287
45722437	45722460	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	0.3604422112949804	[5,5]	[5,3]	6	hSpCas9	positive selection	3091288
45722420	45722443	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.5044772446891995	[3,3]	[4,3]	8	hSpCas9	positive selection	3091289
45722427	45722450		-	24336571	A375	resistance to PLX after 7 days	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	-0.31374032969685617	[8,8]	[6,6]	-8	hSpCas9	positive selection	3147175
45723872	45723895		+	24336571	A375	resistance to PLX after 7 days	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.16342477948781542	[16,15]	[16,18]	5	hSpCas9	positive selection	3147176
45724033	45724056		-	24336571	A375	resistance to PLX after 7 days	TGGTTTGTATTTTGCAACACAGG	SPINT4	ENSG00000149651	0.19900745974359524	[20,18]	[23,20]	6	hSpCas9	positive selection	3147177
45722427	45722450		-	24336571	A375	resistance to PLX after 14 days	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	-0.6792512157852786	[8,8]	[2,1]	-7	hSpCas9	positive selection	3204968
45723872	45723895		+	24336571	A375	resistance to PLX after 14 days	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	1.0475255142541775	[13,15]	[17,10]	8	hSpCas9	positive selection	3204969
45724033	45724056		-	24336571	A375	resistance to PLX after 14 days	TGGTTTGTATTTTGCAACACAGG	SPINT4	ENSG00000149651	0.1900799595848568	[30,23]	[13,13]	2	hSpCas9	positive selection	3204970
45722427	45722450		-	24336571	A375	viability after 7 days	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	-0.9451009487387256	[17]	[8,8]	-8	hSpCas9	negative selection	3262761
45723872	45723895		+	24336571	A375	viability after 7 days	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.17239833148340605	[14]	[16,15]	2	hSpCas9	negative selection	3262762
45724033	45724056		-	24336571	A375	viability after 7 days	TGGTTTGTATTTTGCAACACAGG	SPINT4	ENSG00000149651	0.036810400640930885	[19]	[20,18]	0	hSpCas9	negative selection	3262763
45722427	45722450		-	24336571	A375	viability after 14 days	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	-0.8980620172380909	[17]	[8,8]	-8	hSpCas9	negative selection	3320554
45723872	45723895		+	24336571	A375	viability after 14 days	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.09770983984579684	[14]	[13,15]	1	hSpCas9	negative selection	3320555
45724033	45724056		-	24336571	A375	viability after 14 days	TGGTTTGTATTTTGCAACACAGG	SPINT4	ENSG00000149651	0.49705960170052854	[19]	[30,23]	6	hSpCas9	negative selection	3320556
45723883	45723906	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	-0.748298337748043	[256,256]	[0,0]	-5	hSpCas9	positive selection	3394728
45722364	45722387	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.10757909194115295	[141,141]	[0,0]	0	hSpCas9	positive selection	3394729
45722449	45722472	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.2583736268382073	[182,182]	[0,0]	-1	hSpCas9	positive selection	3394730
45723882	45723905	20	-	26780180	HT29	viability (Avana library 4 designs)	AAATTCATGTCCAATTTGCAGGG	SPINT4	ENSG00000149651	0.148820484496309	[]	[]	0	hSpCas9	negative selection	3462052
45722426	45722449	20	-	26780180	HT29	viability (Avana library 4 designs)	ATTAACACCACCCAATAACAGGG	SPINT4	ENSG00000149651	-0.287868905983756	[]	[]	-5	hSpCas9	negative selection	3462053
45722436	45722459	20	+	26780180	HT29	viability (Avana library 4 designs)	GGGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	-0.233016460506556	[]	[]	-4	hSpCas9	negative selection	3462054
45722419	45722442	20	+	26780180	HT29	viability (Avana library 4 designs)	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	-0.047996375425739	[]	[]	0	hSpCas9	negative selection	3462055
45722426	45722449	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATTAACACCACCCAATAACAGGG	SPINT4	ENSG00000149651	-4.73761726048667	[]	[]	-5	hSpCas9	negative selection	3563398
45722419	45722442	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.286456725730272	[]	[]	0	hSpCas9	negative selection	3563399
45722436	45722459	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	0.170211858190289	[]	[]	0	hSpCas9	negative selection	3563400
45723882	45723905	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAATTCATGTCCAATTTGCAGGG	SPINT4	ENSG00000149651	-6.00530521202635	[]	[]	-6	hSpCas9	negative selection	3563401
45723872	45723895	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.0458740903699537	[]	[]	0	hSpCas9	negative selection	3563402
45722475	45722498	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	5.48712867714005	[]	[]	8	hSpCas9	negative selection	3563403
45722426	45722449	20	-	26780180	A375	viability (Avana lentiGuide)	ATTAACACCACCCAATAACAGGG	SPINT4	ENSG00000149651	-3.57503311796524	[]	[]	-6	hSpCas9	negative selection	3672057
45722419	45722442	20	+	26780180	A375	viability (Avana lentiGuide)	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	1.06592468118643	[]	[]	1	hSpCas9	negative selection	3672058
45722436	45722459	20	+	26780180	A375	viability (Avana lentiGuide)	GGGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	-3.26231293904547	[]	[]	-6	hSpCas9	negative selection	3672059
45723882	45723905	20	-	26780180	A375	viability (Avana lentiGuide)	AAATTCATGTCCAATTTGCAGGG	SPINT4	ENSG00000149651	-6.89768878675644	[]	[]	-9	hSpCas9	negative selection	3672060
45723872	45723895	20	+	26780180	A375	viability (Avana lentiGuide)	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	-2.31668150274048	[]	[]	-4	hSpCas9	negative selection	3672061
45722475	45722498	20	-	26780180	A375	viability (Avana lentiGuide)	GCCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	-6.27795118641791	[]	[]	-9	hSpCas9	negative selection	3672062
45722426	45722449	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTAACACCACCCAATAACAGGG	SPINT4	ENSG00000149651	-0.5299175280648352	[6]	[3,4]	-6	hSpCas9	positive selection	3780664
45722419	45722442	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	-0.06935107040671074	[6]	[5,5]	-1	hSpCas9	positive selection	3780665
45722436	45722459	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	-0.05547793932443135	[6]	[6,5]	-1	hSpCas9	positive selection	3780666
45723882	45723905	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAATTCATGTCCAATTTGCAGGG	SPINT4	ENSG00000149651	-0.09669074856011937	[5]	[5,4]	-2	hSpCas9	positive selection	3780667
45723872	45723895	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.048334812216312015	[5]	[4,5]	1	hSpCas9	positive selection	3780668
45722475	45722498	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	0.3983559395563213	[5]	[6,6]	9	hSpCas9	positive selection	3780669
45722426	45722449	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTAACACCACCCAATAACAGGG	SPINT4	ENSG00000149651	0.25164481177359965	[5]	[6,4]	6	hSpCas9	positive selection	3889271
45722419	45722442	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.11263469610978843	[5]	[6,3]	2	hSpCas9	positive selection	3889272
45722436	45722459	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	0.17845804644110116	[6]	[6,5]	4	hSpCas9	positive selection	3889273
45723882	45723905	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAATTCATGTCCAATTTGCAGGG	SPINT4	ENSG00000149651	0.32621865939725203	[4]	[4,5]	8	hSpCas9	positive selection	3889274
45723872	45723895	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.3414288166887839	[5]	[6,6]	8	hSpCas9	positive selection	3889275
45722475	45722498	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	0.3482981104610148	[5]	[6,6]	8	hSpCas9	positive selection	3889276
45723883	45723906	20	-	26780180	A375	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	1.14623069173129	[]	[]	6	hSpCas9	negative selection	3999019
45722449	45722472	20	+	26780180	A375	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	1.00879999324319	[]	[]	5	hSpCas9	negative selection	3999020
45722364	45722387	20	+	26780180	A375	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	1.00744199409511	[]	[]	4	hSpCas9	negative selection	3999021
45722415	45722438	20	+	26780180	A375	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.601728539091618	[]	[]	2	hSpCas9	negative selection	3999022
45722427	45722450	20	-	26780180	A375	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.444962276497777	[]	[]	1	hSpCas9	negative selection	3999023
45723872	45723895	20	+	26780180	A375	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.930876826444568	[]	[]	4	hSpCas9	negative selection	3999024
45723883	45723906	20	-	26780180	HT29	viability (GeCKOv2 library)	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	1.50233279551774	[]	[]	7	hSpCas9	negative selection	4106985
45722449	45722472	20	+	26780180	HT29	viability (GeCKOv2 library)	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	1.27556994541931	[]	[]	6	hSpCas9	negative selection	4106986
45722364	45722387	20	+	26780180	HT29	viability (GeCKOv2 library)	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.71989563866393	[]	[]	2	hSpCas9	negative selection	4106987
45722415	45722438	20	+	26780180	HT29	viability (GeCKOv2 library)	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.720685707460386	[]	[]	2	hSpCas9	negative selection	4106988
45722427	45722450	20	-	26780180	HT29	viability (GeCKOv2 library)	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.681808638194977	[]	[]	2	hSpCas9	negative selection	4106989
45723872	45723895	20	+	26780180	HT29	viability (GeCKOv2 library)	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.926532440741561	[]	[]	4	hSpCas9	negative selection	4106990
45722427	45722450	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	-0.040963723504064076	[2]	[2,0]	-1	hSpCas9	positive selection	4173344
45723872	45723895	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.3431339440444326	[3]	[2,3]	7	hSpCas9	positive selection	4173345
45724033	45724056	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGTTTGTATTTTGCAACACAGG	SPINT4	ENSG00000149651	0.21648818083127783	[4]	[2,3]	5	hSpCas9	positive selection	4173346
45722427	45722450	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.29793127983190676	[4]	[3,3,3,0]	2	hSpCas9	positive selection	4237366
45723872	45723895	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	1.076640314676618	[3]	[4,0,1,4]	7	hSpCas9	positive selection	4237367
45724033	45724056	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGTTTGTATTTTGCAACACAGG	SPINT4	ENSG00000149651	0.6383382009880391	[3]	[4,2,3,0]	4	hSpCas9	positive selection	4237368
45722427	45722450	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.48952550185556665	[0]	[1,0]	8	hSpCas9	positive selection	4300345
45722415	45722438	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.3148184897752392	[4]	[4,3]	6	hSpCas9	positive selection	4300346
45723872	45723895	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	-0.16235682208418134	[3]	[4,0]	-3	hSpCas9	positive selection	4300347
45723883	45723906	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	-0.21470344862417343	[3]	[2,1]	-4	hSpCas9	positive selection	4364600
45722364	45722387	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.23603226023004814	[2]	[2,1]	5	hSpCas9	positive selection	4364601
45722449	45722472	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.19103266784263162	[3]	[3,0]	-4	hSpCas9	positive selection	4364602
45722437	45722459	20	+	27760321	OCIAML3	viability	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	1.0320298177881337	[18,10]	[36,5]	9	hSpCas9	negative selection	4442811
45722450	45722472	20	+	27760321	OCIAML3	viability	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.7029425910916374	[96,82]	[62,180]	8	hSpCas9	negative selection	4442812
45722475	45722497	20	-	27760321	OCIAML3	viability	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	1.0466308277784777	[289,201]	[299,513]	9	hSpCas9	negative selection	4442813
45723873	45723895	20	+	27760321	OCIAML3	viability	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.2325011549978268	[351,276]	[211,384]	2	hSpCas9	negative selection	4442814
45723886	45723908	20	+	27760321	OCIAML3	viability	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	0.22910124553259026	[236,156]	[175,180]	2	hSpCas9	negative selection	4442815
45722437	45722459	20	+	27760321	OCIAML2	viability	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	1.0927217337657469	[18,10]	[8,46]	9	hSpCas9	negative selection	4526274
45722450	45722472	20	+	27760321	OCIAML2	viability	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.7981350737712982	[96,82]	[95,165]	9	hSpCas9	negative selection	4526275
45722475	45722497	20	-	27760321	OCIAML2	viability	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	0.24755473996795074	[289,201]	[192,286]	3	hSpCas9	negative selection	4526276
45723873	45723895	20	+	27760321	OCIAML2	viability	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.27144919436462284	[351,276]	[270,349]	3	hSpCas9	negative selection	4526277
45723886	45723908	20	+	27760321	OCIAML2	viability	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	0.620718623218383	[236,156]	[233,251]	8	hSpCas9	negative selection	4526278
45722437	45722459	20	+	27760321	MV411	viability	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	0.17822704669024247	[18,10]	[0,25]	1	hSpCas9	negative selection	4609737
45722450	45722472	20	+	27760321	MV411	viability	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	1.7347216455213528	[96,82]	[256,106]	9	hSpCas9	negative selection	4609738
45722475	45722497	20	-	27760321	MV411	viability	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	1.2469478493908217	[289,201]	[493,210]	8	hSpCas9	negative selection	4609739
45723873	45723895	20	+	27760321	MV411	viability	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	1.005766939739724	[351,276]	[449,359]	7	hSpCas9	negative selection	4609740
45723886	45723908	20	+	27760321	MV411	viability	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	0.26738962721374304	[236,156]	[127,193]	2	hSpCas9	negative selection	4609741
45722437	45722459	20	+	27760321	HL60	viability	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	0.6984984547944864	[18,10]	[19,18]	7	hSpCas9	negative selection	4693200
45722450	45722472	20	+	27760321	HL60	viability	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.17386388422959298	[96,82]	[71,93]	2	hSpCas9	negative selection	4693201
45722475	45722497	20	-	27760321	HL60	viability	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	0.06682346371779924	[289,201]	[276,134]	0	hSpCas9	negative selection	4693202
45723873	45723895	20	+	27760321	HL60	viability	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	-0.22698386334051457	[351,276]	[170,267]	-3	hSpCas9	negative selection	4693203
45723886	45723908	20	+	27760321	HL60	viability	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	0.40651300378601285	[236,156]	[158,264]	5	hSpCas9	negative selection	4693204
45722437	45722459	20	+	27760321	HT1080	viability	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	-1.9983308370974173	[10,8]	[0,0]	-6	hSpCas9	negative selection	4776663
45722450	45722472	20	+	27760321	HT1080	viability	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	1.7343578903298567	[82,64]	[131,60]	8	hSpCas9	negative selection	4776664
45722475	45722497	20	-	27760321	HT1080	viability	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	2.4098109217982273	[201,157]	[435,320]	9	hSpCas9	negative selection	4776665
45723873	45723895	20	+	27760321	HT1080	viability	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	1.032001437156135	[276,215]	[227,170]	5	hSpCas9	negative selection	4776666
45723886	45723908	20	+	27760321	HT1080	viability	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	0.7557745992400642	[156,122]	[150,31]	4	hSpCas9	negative selection	4776667
45722437	45722459	20	+	27760321	HT29	viability after 7 days	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	0.5755021705777947	[10,8]	[12,32,10]	8	hSpCas9	negative selection	4860126
45722450	45722472	20	+	27760321	HT29	viability after 7 days	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.5608884194513217	[82,64]	[161,247,17]	8	hSpCas9	negative selection	4860127
45722475	45722497	20	-	27760321	HT29	viability after 7 days	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	0.3275764607142104	[201,157]	[378,290,215]	5	hSpCas9	negative selection	4860128
45723873	45723895	20	+	27760321	HT29	viability after 7 days	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.3527961274442075	[276,215]	[595,436,213]	5	hSpCas9	negative selection	4860129
45723886	45723908	20	+	27760321	HT29	viability after 7 days	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	1.0974754453501523	[156,122]	[213,442,470]	9	hSpCas9	negative selection	4860130
45722437	45722459	20	+	27760321	HT29	viability after 25 days	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	1.3501914216352748	[10,8]	[34,7,45]	9	hSpCas9	negative selection	4943589
45722450	45722472	20	+	27760321	HT29	viability after 25 days	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.7203555717416517	[82,64]	[142,183,84]	7	hSpCas9	negative selection	4943590
45722475	45722497	20	-	27760321	HT29	viability after 25 days	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	0.7331621305529884	[201,157]	[468,218,327]	8	hSpCas9	negative selection	4943591
45723873	45723895	20	+	27760321	HT29	viability after 25 days	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.5763493498507218	[276,215]	[432,384,442]	6	hSpCas9	negative selection	4943592
45723886	45723908	20	+	27760321	HT29	viability after 25 days	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	0.9034182486972361	[156,122]	[122,405,388]	9	hSpCas9	negative selection	4943593
45722437	45722459	20	+	27760321	HT29	viability after 22 days	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	0.16007753346353581	[10,8]	[8,13,15]	1	hSpCas9	negative selection	5027052
45722450	45722472	20	+	27760321	HT29	viability after 22 days	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.7041467708457505	[82,64]	[105,79,233]	7	hSpCas9	negative selection	5027053
45722475	45722497	20	-	27760321	HT29	viability after 22 days	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	0.7479660131669142	[201,157]	[499,243,299]	8	hSpCas9	negative selection	5027054
45723873	45723895	20	+	27760321	HT29	viability after 22 days	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.6115964011231717	[276,215]	[327,446,534]	6	hSpCas9	negative selection	5027055
45723886	45723908	20	+	27760321	HT29	viability after 22 days	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	1.0454209305137028	[156,122]	[97,549,360]	9	hSpCas9	negative selection	5027056
45722437	45722459	20	+	27760321	HT29	viability after 19 days	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	-0.43235396272224946	[10,8]	[0,22,0]	-4	hSpCas9	negative selection	5110515
45722450	45722472	20	+	27760321	HT29	viability after 19 days	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.09314242937741346	[82,64]	[135,32,105]	0	hSpCas9	negative selection	5110516
45722475	45722497	20	-	27760321	HT29	viability after 19 days	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	1.3992934770448668	[201,157]	[358,476,764]	9	hSpCas9	negative selection	5110517
45723873	45723895	20	+	27760321	HT29	viability after 19 days	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.4455586988260789	[276,215]	[653,309,221]	4	hSpCas9	negative selection	5110518
45723886	45723908	20	+	27760321	HT29	viability after 19 days	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	1.1684094715788413	[156,122]	[71,737,243]	9	hSpCas9	negative selection	5110519
45722437	45722459	20	+	27760321	HT29	viability after 16 days	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	0.7147782849185482	[10,8]	[1,44,5]	8	hSpCas9	negative selection	5193978
45722450	45722472	20	+	27760321	HT29	viability after 16 days	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.6420921198106342	[82,64]	[109,161,112]	7	hSpCas9	negative selection	5193979
45722475	45722497	20	-	27760321	HT29	viability after 16 days	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	0.1732974924385744	[201,157]	[321,237,129]	1	hSpCas9	negative selection	5193980
45723873	45723895	20	+	27760321	HT29	viability after 16 days	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.49118082811161984	[276,215]	[292,458,399]	5	hSpCas9	negative selection	5193981
45723886	45723908	20	+	27760321	HT29	viability after 16 days	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	1.3315062359558714	[156,122]	[429,476,276]	9	hSpCas9	negative selection	5193982
45722437	45722459	20	+	27760321	HT29	viability after 13 days	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	2.070138550620221	[10,8]	[73,14,56]	9	hSpCas9	negative selection	5277441
45722450	45722472	20	+	27760321	HT29	viability after 13 days	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.2711964916215295	[82,64]	[108,117,84]	3	hSpCas9	negative selection	5277442
45722475	45722497	20	-	27760321	HT29	viability after 13 days	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	0.22448524036889117	[201,157]	[288,200,241]	2	hSpCas9	negative selection	5277443
45723873	45723895	20	+	27760321	HT29	viability after 13 days	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.7243426727892252	[276,215]	[618,429,373]	8	hSpCas9	negative selection	5277444
45723886	45723908	20	+	27760321	HT29	viability after 13 days	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	0.9217348832287251	[156,122]	[271,406,247]	9	hSpCas9	negative selection	5277445
45722437	45722459	20	+	27760321	HT29	viability after 10 days	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	1.4025311886061305	[10,8]	[32,26,38]	9	hSpCas9	negative selection	5360904
45722450	45722472	20	+	27760321	HT29	viability after 10 days	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.37869422242435036	[82,64]	[114,233,16]	5	hSpCas9	negative selection	5360905
45722475	45722497	20	-	27760321	HT29	viability after 10 days	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	1.1614627248169371	[201,157]	[750,466,293]	9	hSpCas9	negative selection	5360906
45723873	45723895	20	+	27760321	HT29	viability after 10 days	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.20315925899676124	[276,215]	[454,292,313]	2	hSpCas9	negative selection	5360907
45723886	45723908	20	+	27760321	HT29	viability after 10 days	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	1.1642668718479785	[156,122]	[289,507,380]	9	hSpCas9	negative selection	5360908
45722437	45722459	20	+	27760321	MOLM13	viability	GGTGGTGTTAATAAAATTGCGG	SPINT4	ENSG00000149651	2.603233500437255	[18,10]	[23,72]	9	hSpCas9	negative selection	5444367
45722450	45722472	20	+	27760321	MOLM13	viability	AAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.9389917826070404	[96,82]	[203,5]	6	hSpCas9	negative selection	5444368
45722475	45722497	20	-	27760321	MOLM13	viability	CCTTAGCTTCATACCTTTGAGG	SPINT4	ENSG00000149651	1.4791813922291392	[289,201]	[18,691]	8	hSpCas9	negative selection	5444369
45723873	45723895	20	+	27760321	MOLM13	viability	CATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.957600749039484	[351,276]	[276,397]	6	hSpCas9	negative selection	5444370
45723886	45723908	20	+	27760321	MOLM13	viability	GCAAATTGGACATGAATTTTGG	SPINT4	ENSG00000149651	0.6743000579366791	[236,156]	[53,277]	4	hSpCas9	negative selection	5444371
45722427	45722450	20	-	27260156	BXPC3	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.22747674273118434	[57]	[39,64,78,107]	5	hSpCas9	negative selection	5572805
45722415	45722438	20	+	27260156	BXPC3	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.25161909820401007	[1053]	[1137,1295,1354,1492]	5	hSpCas9	negative selection	5572806
45723872	45723895	20	+	27260156	BXPC3	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.14199078725594766	[597]	[661,702,695,696]	3	hSpCas9	negative selection	5572807
45723883	45723906	20	-	27260156	BXPC3	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.5080909784559471	[539]	[680,712,850,1005]	9	hSpCas9	negative selection	5637060
45722364	45722387	20	+	27260156	BXPC3	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.2453507242612578	[245]	[156,333,308,449]	5	hSpCas9	negative selection	5637061
45722449	45722472	20	+	27260156	BXPC3	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.06998231142269686	[508]	[497,547,611,583]	1	hSpCas9	negative selection	5637062
45722427	45722450	20	-	27260156	A673	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.13806721419272527	[57]	[43,82,116,56]	3	hSpCas9	negative selection	5694056
45722415	45722438	20	+	27260156	A673	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.2325632381853706	[1053]	[1583,1390,1414,1573]	5	hSpCas9	negative selection	5694057
45723872	45723895	20	+	27260156	A673	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.17512997327847046	[597]	[894,609,895,856]	4	hSpCas9	negative selection	5694058
45723883	45723906	20	-	27260156	A673	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.28704187788281477	[539]	[922,744,676,837]	6	hSpCas9	negative selection	5758311
45722364	45722387	20	+	27260156	A673	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.2332055690308371	[245]	[460,298,309,331]	5	hSpCas9	negative selection	5758312
45722449	45722472	20	+	27260156	A673	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.321066897801904	[508]	[503,466,499,486]	-7	hSpCas9	negative selection	5758313
45722427	45722450	20	-	27260156	A375	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.8805535918283747	[57]	[110,217,128,60]	9	hSpCas9	negative selection	5815307
45722415	45722438	20	+	27260156	A375	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.4672751400435884	[1053]	[1857,1911,1373,1688]	6	hSpCas9	negative selection	5815308
45723872	45723895	20	+	27260156	A375	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.23026600329209124	[597]	[874,742,845,801]	3	hSpCas9	negative selection	5815309
45723883	45723906	20	-	27260156	A375	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.47837132628528534	[539]	[902,876,886,847]	7	hSpCas9	negative selection	5879562
45722364	45722387	20	+	27260156	A375	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.5496589205329127	[245]	[412,394,438,428]	7	hSpCas9	negative selection	5879563
45722449	45722472	20	+	27260156	A375	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.09106269638755952	[508]	[385,779,609,491]	-1	hSpCas9	negative selection	5879564
45722427	45722450	20	-	27260156	COLO741	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.2946778735545825	[57]	[122,86,66]	6	hSpCas9	negative selection	5936558
45722415	45722438	20	+	27260156	COLO741	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.18560202670497206	[1053]	[1576,1721,1312]	4	hSpCas9	negative selection	5936559
45723872	45723895	20	+	27260156	COLO741	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.1974778111024924	[597]	[1168,748,742]	4	hSpCas9	negative selection	5936560
45723883	45723906	20	-	27260156	COLO741	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.3841296997926793	[539]	[942,972,794]	7	hSpCas9	negative selection	6000813
45722364	45722387	20	+	27260156	COLO741	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	1.6720146937857923	[245]	[677,351,1877]	9	hSpCas9	negative selection	6000814
45722449	45722472	20	+	27260156	COLO741	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.13502384643905843	[508]	[592,513,662]	-3	hSpCas9	negative selection	6000815
45722427	45722450	20	-	27260156	CAL120	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.9223521307211269	[57]	[45,233,116]	9	hSpCas9	negative selection	6057809
45722415	45722438	20	+	27260156	CAL120	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.11603113002909926	[1053]	[1455,1005,1799]	1	hSpCas9	negative selection	6057810
45723872	45723895	20	+	27260156	CAL120	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.4815619256978919	[597]	[1487,703,992]	7	hSpCas9	negative selection	6057811
45723883	45723906	20	-	27260156	CAL120	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.5680561398114208	[539]	[1026,977,987]	8	hSpCas9	negative selection	6122064
45722364	45722387	20	+	27260156	CAL120	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.13634606141817618	[245]	[393,292,330]	2	hSpCas9	negative selection	6122065
45722449	45722472	20	+	27260156	CAL120	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.37240576205582526	[508]	[380,503,564]	-5	hSpCas9	negative selection	6122066
45722427	45722450	20	-	27260156	CADOES1	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.2989340332969159	[57]	[100,16,61,85]	5	hSpCas9	negative selection	6179060
45722415	45722438	20	+	27260156	CADOES1	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.42557112184543877	[1053]	[1447,1227,1348,1237]	7	hSpCas9	negative selection	6179061
45723872	45723895	20	+	27260156	CADOES1	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.27613131103137734	[597]	[658,863,585,581]	4	hSpCas9	negative selection	6179062
45723883	45723906	20	-	27260156	CADOES1	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.5255918462729671	[539]	[891,731,506,761]	8	hSpCas9	negative selection	6243315
45722364	45722387	20	+	27260156	CADOES1	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.5416205266088673	[245]	[425,317,251,335]	8	hSpCas9	negative selection	6243316
45722449	45722472	20	+	27260156	CADOES1	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.019924937018306707	[508]	[487,352,490,537]	0	hSpCas9	negative selection	6243317
45722427	45722450	20	-	27260156	EWS502	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.7409738932400471	[57]	[113,113,62,117]	9	hSpCas9	negative selection	6300311
45722415	45722438	20	+	27260156	EWS502	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.26904669255428404	[1053]	[1101,1299,1415,1608]	5	hSpCas9	negative selection	6300312
45723872	45723895	20	+	27260156	EWS502	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.4310717321072307	[597]	[989,653,631,1145]	7	hSpCas9	negative selection	6300313
45723883	45723906	20	-	27260156	EWS502	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.5549236021068438	[539]	[711,686,803,1201]	8	hSpCas9	negative selection	6364566
45722364	45722387	20	+	27260156	EWS502	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.5413262441019655	[245]	[458,335,311,400]	8	hSpCas9	negative selection	6364567
45722449	45722472	20	+	27260156	EWS502	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.18922513854590917	[508]	[399,513,401,587]	-3	hSpCas9	negative selection	6364568
45722427	45722450	20	-	27260156	EW8	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.31315930116285484	[57]	[115,58,15,55]	6	hSpCas9	negative selection	6421562
45722415	45722438	20	+	27260156	EW8	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.2583748538464774	[1053]	[954,965,918,1252]	5	hSpCas9	negative selection	6421563
45723872	45723895	20	+	27260156	EW8	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.2991554130496792	[597]	[731,597,504,578]	5	hSpCas9	negative selection	6421564
45723883	45723906	20	-	27260156	EW8	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.4331884293077949	[539]	[754,569,483,588]	7	hSpCas9	negative selection	6485817
45722364	45722387	20	+	27260156	EW8	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.28393558029003807	[245]	[337,211,246,182]	5	hSpCas9	negative selection	6485818
45722449	45722472	20	+	27260156	EW8	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.37500636773257917	[508]	[398,247,263,377]	-6	hSpCas9	negative selection	6485819
45722427	45722450	20	-	27260156	CORL105	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.5773641267188201	[57]	[78,136,64,116]	9	hSpCas9	negative selection	6542813
45722415	45722438	20	+	27260156	CORL105	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.3986072607385034	[1053]	[1825,1423,2035,1295]	7	hSpCas9	negative selection	6542814
45723872	45723895	20	+	27260156	CORL105	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.2264636912038226	[597]	[933,656,894,808]	4	hSpCas9	negative selection	6542815
45723883	45723906	20	-	27260156	CORL105	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.4267885202352171	[539]	[849,714,1118,759]	7	hSpCas9	negative selection	6607068
45722364	45722387	20	+	27260156	CORL105	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.02738436250156584	[245]	[305,370,260,229]	0	hSpCas9	negative selection	6607069
45722449	45722472	20	+	27260156	CORL105	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.04563324828939033	[508]	[593,677,494,527]	-1	hSpCas9	negative selection	6607070
45722427	45722450	20	-	27260156	HS294T	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.9958961932677397	[57]	[26,25,103,19]	9	hSpCas9	negative selection	6664064
45722415	45722438	20	+	27260156	HS294T	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.45442091928435024	[1053]	[538,560,527,614]	6	hSpCas9	negative selection	6664065
45723872	45723895	20	+	27260156	HS294T	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.6035941948162925	[597]	[283,389,360,378]	7	hSpCas9	negative selection	6664066
45723883	45723906	20	-	27260156	HS294T	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.3059489429963024	[539]	[221,313,234,262]	4	hSpCas9	negative selection	6728319
45722364	45722387	20	+	27260156	HS294T	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.41421207231292445	[245]	[104,205,72,120]	5	hSpCas9	negative selection	6728320
45722449	45722472	20	+	27260156	HS294T	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.40572883142817406	[508]	[107,136,194,159]	-5	hSpCas9	negative selection	6728321
45722427	45722450	20	-	27260156	HCC44	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.7946340727566876	[57]	[223,81,53,98]	9	hSpCas9	negative selection	6785315
45722415	45722438	20	+	27260156	HCC44	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.09176774869728654	[1053]	[1261,1173,1508,1182]	1	hSpCas9	negative selection	6785316
45723872	45723895	20	+	27260156	HCC44	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.0009282763650720893	[597]	[766,351,897,773]	0	hSpCas9	negative selection	6785317
45723883	45723906	20	-	27260156	HCC44	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.6211230423490863	[539]	[856,856,1226,864]	8	hSpCas9	negative selection	6849570
45722364	45722387	20	+	27260156	HCC44	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.32259314223571933	[245]	[351,342,347,346]	5	hSpCas9	negative selection	6849571
45722449	45722472	20	+	27260156	HCC44	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.1721490440783272	[508]	[725,456,363,494]	-3	hSpCas9	negative selection	6849572
45722427	45722450	20	-	27260156	G402	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.954148423638467	[57]	[157,131,130,129]	9	hSpCas9	negative selection	6906566
45722415	45722438	20	+	27260156	G402	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.4411019779899581	[1053]	[1644,1879,1940,1515]	5	hSpCas9	negative selection	6906567
45723872	45723895	20	+	27260156	G402	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.5530004853515719	[597]	[1033,1855,561,875]	7	hSpCas9	negative selection	6906568
45723883	45723906	20	-	27260156	G402	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.7204410451415777	[539]	[1783,953,720,977]	8	hSpCas9	negative selection	6970821
45722364	45722387	20	+	27260156	G402	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.7887450995270611	[245]	[389,454,262,921]	8	hSpCas9	negative selection	6970822
45722449	45722472	20	+	27260156	G402	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.20215621417061674	[508]	[1181,558,421,748]	2	hSpCas9	negative selection	6970823
45722427	45722450	20	-	27260156	L33	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.06967550614821372	[57]	[37,22,25,107]	1	hSpCas9	negative selection	7027817
45722415	45722438	20	+	27260156	L33	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.14641077304271466	[1053]	[1167,449,813,1105]	3	hSpCas9	negative selection	7027818
45723872	45723895	20	+	27260156	L33	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.327763275601368	[597]	[915,264,425,756]	7	hSpCas9	negative selection	7027819
45723883	45723906	20	-	27260156	L33	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.06286024276393012	[539]	[581,229,357,542]	1	hSpCas9	negative selection	7092072
45722364	45722387	20	+	27260156	L33	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.001498146179308213	[245]	[230,102,151,260]	0	hSpCas9	negative selection	7092073
45722449	45722472	20	+	27260156	L33	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.10587667470321538	[508]	[392,206,364,415]	-2	hSpCas9	negative selection	7092074
45722427	45722450	20	-	27260156	K562	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.9769041165454562	[57]	[96,19,283,9]	9	hSpCas9	negative selection	7149068
45722415	45722438	20	+	27260156	K562	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.6406122311590232	[1053]	[1283,1393,1663,1465]	7	hSpCas9	negative selection	7149069
45723872	45723895	20	+	27260156	K562	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.4437966708759933	[597]	[729,423,679,1001]	5	hSpCas9	negative selection	7149070
45723883	45723906	20	-	27260156	K562	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.7143181264228857	[539]	[901,870,826,579]	8	hSpCas9	negative selection	7213323
45722364	45722387	20	+	27260156	K562	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.2778328461840275	[245]	[235,209,347,258]	3	hSpCas9	negative selection	7213324
45722449	45722472	20	+	27260156	K562	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.00890499954530656	[508]	[793,656,225,186]	0	hSpCas9	negative selection	7213325
45722427	45722450	20	-	27260156	HT29	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.5325858144290785	[57]	[94,195,68,59]	8	hSpCas9	negative selection	7270319
45722415	45722438	20	+	27260156	HT29	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.3492435599314092	[1053]	[1866,1606,1563,1509]	6	hSpCas9	negative selection	7270320
45723872	45723895	20	+	27260156	HT29	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.28671639276964256	[597]	[796,911,824,988]	5	hSpCas9	negative selection	7270321
45723883	45723906	20	-	27260156	HT29	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.4230488333704767	[539]	[1012,839,950,734]	7	hSpCas9	negative selection	7334574
45722364	45722387	20	+	27260156	HT29	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.2054965992610932	[245]	[335,426,327,297]	4	hSpCas9	negative selection	7334575
45722449	45722472	20	+	27260156	HT29	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.12102597061532226	[508]	[762,732,621,590]	2	hSpCas9	negative selection	7334576
45722427	45722450	20	-	27260156	MHHES1	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	1.1380590143953297	[57]	[371,49,83,94]	9	hSpCas9	negative selection	7391570
45722415	45722438	20	+	27260156	MHHES1	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.4941833863640077	[1053]	[1926,1801,1893,1186]	8	hSpCas9	negative selection	7391571
45723872	45723895	20	+	27260156	MHHES1	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.3045660031145714	[597]	[807,852,1036,652]	5	hSpCas9	negative selection	7391572
45723883	45723906	20	-	27260156	MHHES1	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.6573529957818631	[539]	[1169,782,1173,746]	9	hSpCas9	negative selection	7455825
45722364	45722387	20	+	27260156	MHHES1	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.19928116468221924	[245]	[359,280,381,257]	3	hSpCas9	negative selection	7455826
45722449	45722472	20	+	27260156	MHHES1	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.20045491056750775	[508]	[842,700,711,441]	3	hSpCas9	negative selection	7455827
45722427	45722450	20	-	27260156	MEWO	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	-0.1391842640744403	[57]	[29,63,49]	-3	hSpCas9	negative selection	7512821
45722415	45722438	20	+	27260156	MEWO	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.1679604457682906	[1053]	[1199,924,1216]	3	hSpCas9	negative selection	7512822
45723872	45723895	20	+	27260156	MEWO	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.1966902020652137	[597]	[620,538,759]	4	hSpCas9	negative selection	7512823
45723883	45723906	20	-	27260156	MEWO	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.5623851288945814	[539]	[847,684,724]	9	hSpCas9	negative selection	7577076
45722364	45722387	20	+	27260156	MEWO	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.027448608228393456	[245]	[230,226,244]	0	hSpCas9	negative selection	7577077
45722449	45722472	20	+	27260156	MEWO	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.35548368617831194	[508]	[440,341,346]	-6	hSpCas9	negative selection	7577078
45722427	45722450	20	-	27260156	LNCAPCLONEFGC	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.5602658793765207	[57]	[46,69,77,115]	8	hSpCas9	negative selection	7634072
45722415	45722438	20	+	27260156	LNCAPCLONEFGC	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.3850748527337968	[1053]	[1132,1121,1488,1288]	6	hSpCas9	negative selection	7634073
45723872	45723895	20	+	27260156	LNCAPCLONEFGC	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.2741372782371987	[597]	[567,645,741,678]	4	hSpCas9	negative selection	7634074
45723883	45723906	20	-	27260156	LNCAPCLONEFGC	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.5595668634266571	[539]	[698,575,745,875]	8	hSpCas9	negative selection	7698327
45722364	45722387	20	+	27260156	LNCAPCLONEFGC	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.6174126900958465	[245]	[286,293,358,433]	8	hSpCas9	negative selection	7698328
45722449	45722472	20	+	27260156	LNCAPCLONEFGC	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.15355852844578433	[508]	[353,399,461,450]	-2	hSpCas9	negative selection	7698329
45722427	45722450	20	-	27260156	PANC0327	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	-0.11865471253419768	[57]	[60,31,87,11]	-2	hSpCas9	negative selection	7755323
45722415	45722438	20	+	27260156	PANC0327	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.4098297528252215	[1053]	[1790,859,1424,993]	6	hSpCas9	negative selection	7755324
45723872	45723895	20	+	27260156	PANC0327	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.1866630463087544	[597]	[705,524,713,491]	2	hSpCas9	negative selection	7755325
45723883	45723906	20	-	27260156	PANC0327	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.6169718186111525	[539]	[661,526,666,1106]	8	hSpCas9	negative selection	7819578
45722364	45722387	20	+	27260156	PANC0327	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.736256328434018	[245]	[703,207,317,273]	9	hSpCas9	negative selection	7819579
45722449	45722472	20	+	27260156	PANC0327	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.12613229975831391	[508]	[298,349,502,503]	-2	hSpCas9	negative selection	7819580
45722427	45722450	20	-	27260156	NCIH2009	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.5699318114440781	[57]	[136,118,107]	7	hSpCas9	negative selection	7876574
45722415	45722438	20	+	27260156	NCIH2009	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.529027479876635	[1053]	[2476,2107,1855]	7	hSpCas9	negative selection	7876575
45723872	45723895	20	+	27260156	NCIH2009	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.5188276775307468	[597]	[1601,1212,853]	7	hSpCas9	negative selection	7876576
45723883	45723906	20	-	27260156	NCIH2009	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.18300306416409187	[539]	[848,997,716]	2	hSpCas9	negative selection	7940829
45722364	45722387	20	+	27260156	NCIH2009	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	-0.024343502010094498	[245]	[389,368,263]	0	hSpCas9	negative selection	7940830
45722449	45722472	20	+	27260156	NCIH2009	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.12113567926980996	[508]	[724,630,618]	-2	hSpCas9	negative selection	7940831
45722427	45722450	20	-	27260156	NCIH1373	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	1.330975985291354	[57]	[120,224,193,24]	9	hSpCas9	negative selection	7997825
45722415	45722438	20	+	27260156	NCIH1373	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.9979301113240722	[1053]	[2342,2286,1878,779]	8	hSpCas9	negative selection	7997826
45723872	45723895	20	+	27260156	NCIH1373	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.5358883077339095	[597]	[1243,858,1106,185]	5	hSpCas9	negative selection	7997827
45723883	45723906	20	-	27260156	NCIH1373	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.9539257775931129	[539]	[1087,944,1136,406]	8	hSpCas9	negative selection	8062080
45722364	45722387	20	+	27260156	NCIH1373	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.704897681309917	[245]	[561,656,240,85]	7	hSpCas9	negative selection	8062081
45722449	45722472	20	+	27260156	NCIH1373	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.09489948064360561	[508]	[542,899,439,132]	0	hSpCas9	negative selection	8062082
45722427	45722450	20	-	27260156	PATU8902	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	1.4384734602099427	[57]	[10,137,410,272]	9	hSpCas9	negative selection	8119076
45722415	45722438	20	+	27260156	PATU8902	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.6508214661753524	[1053]	[1663,2525,1766,3539]	7	hSpCas9	negative selection	8119077
45723872	45723895	20	+	27260156	PATU8902	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.6897753063864323	[597]	[862,1589,1185,1829]	7	hSpCas9	negative selection	8119078
45723883	45723906	20	-	27260156	PATU8902	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.8948451762550094	[539]	[1310,1583,1375,1307]	8	hSpCas9	negative selection	8183331
45722364	45722387	20	+	27260156	PATU8902	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.9144267140767801	[245]	[684,1112,126,807]	8	hSpCas9	negative selection	8183332
45722449	45722472	20	+	27260156	PATU8902	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.33498601038881504	[508]	[1494,801,682,600]	3	hSpCas9	negative selection	8183333
45722427	45722450	20	-	27260156	PANC1	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.8241773608542466	[57]	[75,111,169,11]	9	hSpCas9	negative selection	8240327
45722415	45722438	20	+	27260156	PANC1	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.2982980199095986	[1053]	[1145,1229,1368,771]	5	hSpCas9	negative selection	8240328
45723872	45723895	20	+	27260156	PANC1	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.6681328299356983	[597]	[647,1049,864,750]	9	hSpCas9	negative selection	8240329
45723883	45723906	20	-	27260156	PANC1	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.40148895020044184	[539]	[648,707,534,572]	6	hSpCas9	negative selection	8304582
45722364	45722387	20	+	27260156	PANC1	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.43180689927079263	[245]	[478,166,195,266]	7	hSpCas9	negative selection	8304583
45722449	45722472	20	+	27260156	PANC1	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.10950232537264988	[508]	[522,757,326,347]	1	hSpCas9	negative selection	8304584
45722427	45722450	20	-	27260156	PANC0813	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.6670510637055553	[57]	[188,78,66,104]	9	hSpCas9	negative selection	8361578
45722415	45722438	20	+	27260156	PANC0813	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.4696191322739922	[1053]	[2168,1831,1381,1522]	7	hSpCas9	negative selection	8361579
45723872	45723895	20	+	27260156	PANC0813	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.6403961953418497	[597]	[1101,1104,1068,1101]	8	hSpCas9	negative selection	8361580
45723883	45723906	20	-	27260156	PANC0813	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.2591220401622356	[539]	[906,851,826,478]	4	hSpCas9	negative selection	8425833
45722364	45722387	20	+	27260156	PANC0813	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	-0.0700657644619691	[245]	[369,271,243,225]	-1	hSpCas9	negative selection	8425834
45722449	45722472	20	+	27260156	PANC0813	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.18387968511761116	[508]	[738,682,571,723]	3	hSpCas9	negative selection	8425835
45722427	45722450	20	-	27260156	RDES	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.9213167973512637	[57]	[99,105,143,165]	9	hSpCas9	negative selection	8482829
45722415	45722438	20	+	27260156	RDES	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.362581633988061	[1053]	[1324,1384,1675,1927]	6	hSpCas9	negative selection	8482830
45723872	45723895	20	+	27260156	RDES	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.05088658307275523	[597]	[577,755,705,829]	0	hSpCas9	negative selection	8482831
45723883	45723906	20	-	27260156	RDES	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.698091931701225	[539]	[860,947,1008,1255]	9	hSpCas9	negative selection	8547084
45722364	45722387	20	+	27260156	RDES	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.5053167065830128	[245]	[350,369,493,394]	7	hSpCas9	negative selection	8547085
45722449	45722472	20	+	27260156	RDES	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.026112959225763774	[508]	[520,424,750,624]	0	hSpCas9	negative selection	8547086
45722427	45722450	20	-	27260156	PC3	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	-0.020357150145581926	[57]	[15,23,85,133]	0	hSpCas9	negative selection	8604080
45722415	45722438	20	+	27260156	PC3	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.20415391705077646	[1053]	[801,1237,2053,1124]	4	hSpCas9	negative selection	8604081
45723872	45723895	20	+	27260156	PC3	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.2992604940544249	[597]	[530,770,1136,652]	6	hSpCas9	negative selection	8604082
45723883	45723906	20	-	27260156	PC3	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.31322893015402176	[539]	[407,534,1162,827]	6	hSpCas9	negative selection	8668335
45722364	45722387	20	+	27260156	PC3	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.3990676541521898	[245]	[168,389,633,254]	8	hSpCas9	negative selection	8668336
45722449	45722472	20	+	27260156	PC3	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.09830984322001791	[508]	[288,680,844,530]	2	hSpCas9	negative selection	8668337
45722427	45722450	20	-	27260156	PATU8988T	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.9526974648851554	[57]	[208,81,56,81]	9	hSpCas9	negative selection	8725331
45722415	45722438	20	+	27260156	PATU8988T	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.34644281422399836	[1053]	[1472,1116,1121,1466]	6	hSpCas9	negative selection	8725332
45723872	45723895	20	+	27260156	PATU8988T	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	-0.059588314264974074	[597]	[413,634,604,571]	-1	hSpCas9	negative selection	8725333
45723883	45723906	20	-	27260156	PATU8988T	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.24534402024345567	[539]	[625,635,643,564]	4	hSpCas9	negative selection	8789586
45722364	45722387	20	+	27260156	PATU8988T	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.31172379137645156	[245]	[537,142,135,355]	5	hSpCas9	negative selection	8789587
45722449	45722472	20	+	27260156	PATU8988T	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.004576573255788641	[508]	[457,613,545,354]	0	hSpCas9	negative selection	8789588
45722427	45722450	20	-	27260156	T47D	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.04234669944104441	[57]	[85,50,71,70]	0	hSpCas9	negative selection	8846582
45722415	45722438	20	+	27260156	T47D	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.2927580655584454	[1053]	[1705,1272,1477,1582]	6	hSpCas9	negative selection	8846583
45723872	45723895	20	+	27260156	T47D	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.2563706510424828	[597]	[750,764,889,929]	5	hSpCas9	negative selection	8846584
45723883	45723906	20	-	27260156	T47D	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.4554521341051664	[539]	[773,778,760,1153]	8	hSpCas9	negative selection	8910837
45722364	45722387	20	+	27260156	T47D	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.2554192392525302	[245]	[428,327,270,342]	5	hSpCas9	negative selection	8910838
45722449	45722472	20	+	27260156	T47D	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.065370392724138	[508]	[632,480,612,545]	-1	hSpCas9	negative selection	8910839
45722427	45722450	20	-	27260156	SU8686	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.709404605819115	[57]	[96,94,105,73]	9	hSpCas9	negative selection	8967833
45722415	45722438	20	+	27260156	SU8686	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.3486953091708598	[1053]	[1327,1130,1227,1710]	6	hSpCas9	negative selection	8967834
45723872	45723895	20	+	27260156	SU8686	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.4498662979808815	[597]	[765,757,937,781]	7	hSpCas9	negative selection	8967835
45723883	45723906	20	-	27260156	SU8686	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.45260762440893254	[539]	[528,735,777,939]	7	hSpCas9	negative selection	9032088
45722364	45722387	20	+	27260156	SU8686	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	-0.08384072904208262	[245]	[253,175,232,265]	-1	hSpCas9	negative selection	9032089
45722449	45722472	20	+	27260156	SU8686	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.2557973946574076	[508]	[569,482,529,885]	4	hSpCas9	negative selection	9032090
45722427	45722450	20	-	27260156	SKES1	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	-0.5177524943406295	[57]	[92,15,27,29]	-8	hSpCas9	negative selection	9089084
45722415	45722438	20	+	27260156	SKES1	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.24561665774269792	[1053]	[1238,1264,1365,1117]	5	hSpCas9	negative selection	9089085
45723872	45723895	20	+	27260156	SKES1	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.29255063226781786	[597]	[815,799,633,690]	6	hSpCas9	negative selection	9089086
45723883	45723906	20	-	27260156	SKES1	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.4831352805892666	[539]	[813,832,700,682]	8	hSpCas9	negative selection	9153339
45722364	45722387	20	+	27260156	SKES1	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.3246931217980107	[245]	[392,295,329,226]	6	hSpCas9	negative selection	9153340
45722449	45722472	20	+	27260156	SKES1	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.00839227546317986	[508]	[515,646,518,366]	0	hSpCas9	negative selection	9153341
45722427	45722450	20	-	27260156	TOV112D	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.2680753383315855	[57]	[52,158,47,40]	5	hSpCas9	negative selection	9210335
45722415	45722438	20	+	27260156	TOV112D	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.18640946476762488	[1053]	[1254,1236,1257,1069]	3	hSpCas9	negative selection	9210336
45723872	45723895	20	+	27260156	TOV112D	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.29485389247709604	[597]	[835,1020,543,618]	5	hSpCas9	negative selection	9210337
45723883	45723906	20	-	27260156	TOV112D	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.29901717291890784	[539]	[868,669,736,409]	5	hSpCas9	negative selection	9274590
45722364	45722387	20	+	27260156	TOV112D	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.4550071351727948	[245]	[231,421,434,274]	8	hSpCas9	negative selection	9274591
45722449	45722472	20	+	27260156	TOV112D	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.10176972203905396	[508]	[474,653,465,351]	-2	hSpCas9	negative selection	9274592
45722427	45722450	20	-	27260156	TC71	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.09838816744086687	[57]	[56,77,59,71]	2	hSpCas9	negative selection	9331586
45722415	45722438	20	+	27260156	TC71	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.09966163204751921	[1053]	[1158,1251,1014,1437]	2	hSpCas9	negative selection	9331587
45723872	45723895	20	+	27260156	TC71	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.24364890092619162	[597]	[720,781,814,713]	6	hSpCas9	negative selection	9331588
45723883	45723906	20	-	27260156	TC71	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.24404414036935754	[539]	[640,694,659,751]	6	hSpCas9	negative selection	9395841
45722364	45722387	20	+	27260156	TC71	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.003026783747211992	[245]	[242,211,316,284]	0	hSpCas9	negative selection	9395842
45722449	45722472	20	+	27260156	TC71	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	-0.23266284728347975	[508]	[393,424,436,612]	-6	hSpCas9	negative selection	9395843
45722427	45722450	20	-	27260156	TC32	viability	TATTAACACCACCCAATAACAGG	SPINT4	ENSG00000149651	0.667640552266942	[57]	[101,53,111,87]	9	hSpCas9	negative selection	9452837
45722415	45722438	20	+	27260156	TC32	viability	CTCATTGAATACCCTGTTATTGG	SPINT4	ENSG00000149651	0.39821560875298734	[1053]	[1085,929,1781,1618]	7	hSpCas9	negative selection	9452838
45723872	45723895	20	+	27260156	TC32	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.407910980371881	[597]	[689,433,929,1061]	7	hSpCas9	negative selection	9452839
45723883	45723906	20	-	27260156	TC32	viability	AAAATTCATGTCCAATTTGCAGG	SPINT4	ENSG00000149651	0.45288787154409127	[539]	[743,429,840,850]	7	hSpCas9	negative selection	9517092
45722364	45722387	20	+	27260156	TC32	viability	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.4856789706707883	[245]	[240,338,342,360]	8	hSpCas9	negative selection	9517093
45722449	45722472	20	+	27260156	TC32	viability	AAAATTGCGGAGAAGATATGTGG	SPINT4	ENSG00000149651	0.12787074642020796	[508]	[680,312,637,504]	2	hSpCas9	negative selection	9517094
45722364	45722387	20	+	27869803	HPAFII	viability after 27 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	-0.20366407890254923	[367]	[191,147,NaN]	-1	hSpCas9	negative selection	9577869
45722364	45722387	20	+	27869803	HPAFII	viability after 15 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.39538536926288936	[367]	[690,413,NaN]	4	hSpCas9	negative selection	9660318
45722364	45722387	20	+	27869803	ASPC1	viability after 36 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	-0.1374019744228715	[883]	[422,361,112]	-1	hSpCas9	negative selection	9742767
45722364	45722387	20	+	27869803	PATU8988S	viability after 35 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.15791825629900214	[796]	[411,303,NaN]	1	hSpCas9	negative selection	9825216
45722364	45722387	20	+	27869803	PATU8988S	viability after 31 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	0.3151556596794608	[796]	[335,470,NaN]	4	hSpCas9	negative selection	9907665
45722364	45722387	20	+	27869803	HPAFII	viability after 35 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	-0.5867253576775523	[367]	[100,149,NaN]	-4	hSpCas9	negative selection	9990114
45722364	45722387	20	+	27869803	HPAFII	viability after 31 days	CACCATGAAGTCTGCCAAGCTGG	SPINT4	ENSG00000149651	-0.2935859751998968	[367]	[201,131,NaN]	-2	hSpCas9	negative selection	10072563
45722461	45722484	20	+	28162770	P31FUJ	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	0.37701548499305315	[210]	[321]	4	hSpCas9	negative selection	10242165
45723979	45724002	20	-	28162770	P31FUJ	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.11049954126555073	[200]	[254]	1	hSpCas9	negative selection	10242166
45722419	45722442	20	+	28162770	P31FUJ	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.45797714079384666	[437]	[706]	5	hSpCas9	negative selection	10242167
45722378	45722401	20	-	28162770	P31FUJ	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.2503135368937821	[356]	[498]	2	hSpCas9	negative selection	10242168
45722365	45722388	20	+	28162770	P31FUJ	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	0.16312647191676044	[18]	[24]	1	hSpCas9	negative selection	10242169
45723872	45723895	20	+	28162770	P31FUJ	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.6393029609417242	[1054]	[1930]	7	hSpCas9	negative selection	10242170
45722461	45722484	20	+	28162770	TF1	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	NaN	[NaN]	[451]	1	hSpCas9	negative selection	10411531
45723979	45724002	20	-	28162770	TF1	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10411532
45722419	45722442	20	+	28162770	TF1	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	NaN	[NaN]	[559]	1	hSpCas9	negative selection	10411533
45722378	45722401	20	-	28162770	TF1	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	NaN	[NaN]	[366]	1	hSpCas9	negative selection	10411534
45722365	45722388	20	+	28162770	TF1	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	NaN	[NaN]	[92]	1	hSpCas9	negative selection	10411535
45723872	45723895	20	+	28162770	TF1	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	NaN	[NaN]	[1348]	1	hSpCas9	negative selection	10411536
45722461	45722484	20	+	28162770	SKM1	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	-0.08864735740817825	[79]	[132]	0	hSpCas9	negative selection	10580897
45723979	45724002	20	-	28162770	SKM1	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	-0.37454272105078434	[76]	[104]	-3	hSpCas9	negative selection	10580898
45722419	45722442	20	+	28162770	SKM1	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.6109577092541008	[129]	[350]	6	hSpCas9	negative selection	10580899
45722378	45722401	20	-	28162770	SKM1	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.6542131394471258	[100]	[280]	6	hSpCas9	negative selection	10580900
45722365	45722388	20	+	28162770	SKM1	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	-0.05646695165902882	[9]	[16]	0	hSpCas9	negative selection	10580901
45723872	45723895	20	+	28162770	SKM1	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.6196656411394525	[207]	[564]	6	hSpCas9	negative selection	10580902
45722461	45722484	20	+	28162770	SKM1	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	-0.08864735740817825	[79]	[132]	0	hSpCas9	negative selection	10750263
45723979	45724002	20	-	28162770	SKM1	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	-0.37454272105078434	[76]	[104]	-3	hSpCas9	negative selection	10750264
45722419	45722442	20	+	28162770	SKM1	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.6109577092541008	[129]	[350]	6	hSpCas9	negative selection	10750265
45722378	45722401	20	-	28162770	SKM1	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.6542131394471258	[100]	[280]	6	hSpCas9	negative selection	10750266
45722365	45722388	20	+	28162770	SKM1	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	-0.05646695165902882	[9]	[16]	0	hSpCas9	negative selection	10750267
45723872	45723895	20	+	28162770	SKM1	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.6196656411394525	[207]	[564]	6	hSpCas9	negative selection	10750268
45722461	45722484	20	+	28162770	PL21	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	1.832206350337519	[230]	[357]	9	hSpCas9	negative selection	10919629
45723979	45724002	20	-	28162770	PL21	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.2505131370044392	[196]	[101]	2	hSpCas9	negative selection	10919630
45722419	45722442	20	+	28162770	PL21	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.3731772277989682	[462]	[260]	3	hSpCas9	negative selection	10919631
45722378	45722401	20	-	28162770	PL21	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.6151771137681641	[389]	[259]	5	hSpCas9	negative selection	10919632
45722365	45722388	20	+	28162770	PL21	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	-0.6623568617607449	[39]	[10]	-4	hSpCas9	negative selection	10919633
45723872	45723895	20	+	28162770	PL21	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	-0.136002339617743	[764]	[302]	-1	hSpCas9	negative selection	10919634
45722461	45722484	20	+	28162770	P31FUJ	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	0.37701548499305315	[210]	[321]	4	hSpCas9	negative selection	11088995
45723979	45724002	20	-	28162770	P31FUJ	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.11049954126555073	[200]	[254]	1	hSpCas9	negative selection	11088996
45722419	45722442	20	+	28162770	P31FUJ	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.45797714079384666	[437]	[706]	5	hSpCas9	negative selection	11088997
45722378	45722401	20	-	28162770	P31FUJ	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.2503135368937821	[356]	[498]	2	hSpCas9	negative selection	11088998
45722365	45722388	20	+	28162770	P31FUJ	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	0.16312647191676044	[18]	[24]	1	hSpCas9	negative selection	11088999
45723872	45723895	20	+	28162770	P31FUJ	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.6393029609417242	[1054]	[1930]	7	hSpCas9	negative selection	11089000
45722461	45722484	20	+	28162770	OCIAML5	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	-0.1199179929955666	[179]	[298]	-1	hSpCas9	negative selection	11258361
45723979	45724002	20	-	28162770	OCIAML5	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	-0.040622760738514285	[150]	[264]	0	hSpCas9	negative selection	11258362
45722419	45722442	20	+	28162770	OCIAML5	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.7588577237211143	[256]	[784]	6	hSpCas9	negative selection	11258363
45722378	45722401	20	-	28162770	OCIAML5	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.3211261444122264	[195]	[441]	2	hSpCas9	negative selection	11258364
45722365	45722388	20	+	28162770	OCIAML5	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	1.370325850472451	[8]	[41]	9	hSpCas9	negative selection	11258365
45723872	45723895	20	+	28162770	OCIAML5	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	1.0256090463197918	[571]	[2101]	8	hSpCas9	negative selection	11258366
45722461	45722484	20	+	28162770	EOL1	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	1.1674930248274624	[457]	[541]	8	hSpCas9	negative selection	11427727
45723979	45724002	20	-	28162770	EOL1	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	2.033448427024166	[388]	[838]	9	hSpCas9	negative selection	11427728
45722419	45722442	20	+	28162770	EOL1	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.3293102870159885	[774]	[512]	3	hSpCas9	negative selection	11427729
45722378	45722401	20	-	28162770	EOL1	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.3718616738731344	[662]	[451]	3	hSpCas9	negative selection	11427730
45722365	45722388	20	+	28162770	EOL1	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	-0.04848518082919595	[52]	[26]	0	hSpCas9	negative selection	11427731
45723872	45723895	20	+	28162770	EOL1	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.5284720764844644	[1032]	[784]	5	hSpCas9	negative selection	11427732
45722461	45722484	20	+	28162770	MOLM13	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	0.8800152854035195	[371]	[494]	6	hSpCas9	negative selection	11597093
45723979	45724002	20	-	28162770	MOLM13	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.6413203264884266	[273]	[308]	5	hSpCas9	negative selection	11597094
45722419	45722442	20	+	28162770	MOLM13	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.6775942849722458	[619]	[716]	5	hSpCas9	negative selection	11597095
45722378	45722401	20	-	28162770	MOLM13	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.4174403588572211	[581]	[561]	3	hSpCas9	negative selection	11597096
45722365	45722388	20	+	28162770	MOLM13	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	0.7309237873783727	[49]	[59]	5	hSpCas9	negative selection	11597097
45723872	45723895	20	+	28162770	MOLM13	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.647451841595108	[1176]	[1332]	5	hSpCas9	negative selection	11597098
45722461	45722484	20	+	28162770	HEL	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	0.9485472615244424	[359]	[444]	8	hSpCas9	negative selection	11766459
45723979	45724002	20	-	28162770	HEL	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.6375211227293377	[276]	[275]	5	hSpCas9	negative selection	11766460
45722419	45722442	20	+	28162770	HEL	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.8242589719212767	[536]	[608]	7	hSpCas9	negative selection	11766461
45722378	45722401	20	-	28162770	HEL	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	1.4479891657330377	[391]	[684]	9	hSpCas9	negative selection	11766462
45722365	45722388	20	+	28162770	HEL	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	1.6110299722730188	[22]	[44]	9	hSpCas9	negative selection	11766463
45723872	45723895	20	+	28162770	HEL	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.8469133953955796	[887]	[1022]	7	hSpCas9	negative selection	11766464
45722461	45722484	20	+	28162770	MV411	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	0.05598330661900175	[345]	[302]	0	hSpCas9	negative selection	11935825
45723979	45724002	20	-	28162770	MV411	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.29050627267466145	[197]	[203]	2	hSpCas9	negative selection	11935826
45722419	45722442	20	+	28162770	MV411	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.13596226392033572	[389]	[360]	1	hSpCas9	negative selection	11935827
45722378	45722401	20	-	28162770	MV411	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.47245305473436106	[313]	[366]	4	hSpCas9	negative selection	11935828
45722365	45722388	20	+	28162770	MV411	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	-0.30510347224600354	[21]	[14]	-2	hSpCas9	negative selection	11935829
45723872	45723895	20	+	28162770	MV411	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.7599580388352922	[632]	[902]	7	hSpCas9	negative selection	11935830
45722461	45722484	20	+	28162770	MONOMAC1	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	0.36433883334398653	[184]	[272]	3	hSpCas9	negative selection	12105191
45723979	45724002	20	-	28162770	MONOMAC1	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	-0.07719707705355046	[126]	[137]	0	hSpCas9	negative selection	12105192
45722419	45722442	20	+	28162770	MONOMAC1	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.8755799562479909	[338]	[712]	7	hSpCas9	negative selection	12105193
45722378	45722401	20	-	28162770	MONOMAC1	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.9031736137070716	[284]	[610]	8	hSpCas9	negative selection	12105194
45722365	45722388	20	+	28162770	MONOMAC1	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	0.025355574276894277	[23]	[27]	0	hSpCas9	negative selection	12105195
45723872	45723895	20	+	28162770	MONOMAC1	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.9810372247270709	[509]	[1153]	8	hSpCas9	negative selection	12105196
45722461	45722484	20	+	28162770	OCIAML2	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	0.24759920634245935	[61]	[407]	2	hSpCas9	negative selection	12274557
45723979	45724002	20	-	28162770	OCIAML2	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.5988552750791226	[37]	[318]	6	hSpCas9	negative selection	12274558
45722419	45722442	20	+	28162770	OCIAML2	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.4553695933140618	[94]	[721]	4	hSpCas9	negative selection	12274559
45722378	45722401	20	-	28162770	OCIAML2	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	0.35690297875307353	[70]	[503]	3	hSpCas9	negative selection	12274560
45722365	45722388	20	+	28162770	OCIAML2	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	0.6992951762001511	[3]	[35]	6	hSpCas9	negative selection	12274561
45723872	45723895	20	+	28162770	OCIAML2	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.5096647654102799	[128]	[1017]	5	hSpCas9	negative selection	12274562
45722461	45722484	20	+	28162770	OCIAML3	viability	AAGATATGTGGAGACCTCAAAGG	SPINT4	ENSG00000149651	0.4361543301860893	[70]	[289]	4	hSpCas9	negative selection	12443923
45723979	45724002	20	-	28162770	OCIAML3	viability	GTTAAGGTTGCCATTACAGCCGG	SPINT4	ENSG00000149651	0.05369061574495579	[59]	[187]	0	hSpCas9	negative selection	12443924
45722419	45722442	20	+	28162770	OCIAML3	viability	TTGAATACCCTGTTATTGGGTGG	SPINT4	ENSG00000149651	0.9269163646579837	[118]	[682]	7	hSpCas9	negative selection	12443925
45722378	45722401	20	-	28162770	OCIAML3	viability	TCTTAGAAGAAATCCCAGCTTGG	SPINT4	ENSG00000149651	-0.1959232743265168	[106]	[281]	-1	hSpCas9	negative selection	12443926
45722365	45722388	20	+	28162770	OCIAML3	viability	ACCATGAAGTCTGCCAAGCTGGG	SPINT4	ENSG00000149651	1.521469577095773	[5]	[51]	9	hSpCas9	negative selection	12443927
45723872	45723895	20	+	28162770	OCIAML3	viability	TCATGCAGATCCCTGCAAATTGG	SPINT4	ENSG00000149651	0.7695395437649384	[204]	[1054]	7	hSpCas9	negative selection	12443928