Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:161742
• Symbol:SPRED1
• Description:sprouty related EVH1 domain containing 1

DataSource: http://genomecrispr.dkfz.de/#!/results/SPRED1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
38349459	38349482	15	+	26472758	Jiyoye	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	-0.5928246184941266	[247]	[123]	-4	hSpCas9	negative selection	155604
38339804	38339827	15	-	26472758	Jiyoye	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	0.5342872994092126	[75]	[82]	4	hSpCas9	negative selection	155605
38253173	38253196	15	+	26472758	Jiyoye	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	4.494638222756212	[0]	[16]	9	hSpCas9	negative selection	155606
38299407	38299430	15	+	26472758	Jiyoye	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.34577483684172994	[311]	[298]	2	hSpCas9	negative selection	155607
38299526	38299549	15	+	26472758	Jiyoye	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	1.4388842412332115	[44]	[91]	8	hSpCas9	negative selection	155608
38299426	38299449	15	+	26472758	Jiyoye	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	-0.3601021011763954	[496]	[291]	-3	hSpCas9	negative selection	155609
38349445	38349468	15	+	26472758	Jiyoye	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.3903015629414772	[343]	[339]	3	hSpCas9	negative selection	155610
38322287	38322310	15	+	26472758	Jiyoye	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	2.062039895457186	[46]	[147]	8	hSpCas9	negative selection	155611
38322342	38322365	15	+	26472758	Jiyoye	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	1.7733032803037707	[89]	[231]	8	hSpCas9	negative selection	155612
38322349	38322372	15	-	26472758	Jiyoye	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	1.103783238055939	[28]	[46]	7	hSpCas9	negative selection	155613
38349459	38349482	15	+	26472758	KBM7	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	-0.20399572815765618	[762,491]	[237,263]	-2	hSpCas9	negative selection	346722
38339804	38339827	15	-	26472758	KBM7	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	0.5497597427565275	[174,208]	[86,175]	6	hSpCas9	negative selection	346723
38253173	38253196	15	+	26472758	KBM7	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	1.1291913844787107	[98,55]	[80,74]	9	hSpCas9	negative selection	346724
38299407	38299430	15	+	26472758	KBM7	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.3279967031236697	[982,758]	[569,455]	3	hSpCas9	negative selection	346725
38299526	38299549	15	+	26472758	KBM7	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	0.35116122047925524	[216,220]	[214,57]	4	hSpCas9	negative selection	346726
38299426	38299449	15	+	26472758	KBM7	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	0.02191182305240935	[1763,1272]	[877,571]	0	hSpCas9	negative selection	346727
38349445	38349468	15	+	26472758	KBM7	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.5531056889685508	[1541,1402]	[1121,920]	6	hSpCas9	negative selection	346728
38322287	38322310	15	+	26472758	KBM7	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	1.0091294448842847	[538,545]	[662,384]	9	hSpCas9	negative selection	346729
38322342	38322365	15	+	26472758	KBM7	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	0.79170868185425	[1060,1138]	[818,977]	8	hSpCas9	negative selection	346730
38322349	38322372	15	-	26472758	KBM7	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.7475635717618809	[196,297]	[220,181]	7	hSpCas9	negative selection	346731
38349459	38349482	15	+	26472758	Raji	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	1.36471558184321	[168]	[100]	9	hSpCas9	negative selection	537840
38339804	38339827	15	-	26472758	Raji	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	1.995490655302702	[66]	[61]	9	hSpCas9	negative selection	537841
38253173	38253196	15	+	26472758	Raji	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	1.7068456057898709	[32]	[24]	9	hSpCas9	negative selection	537842
38299407	38299430	15	+	26472758	Raji	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.3642918384105518	[471]	[140]	3	hSpCas9	negative selection	537843
38299526	38299549	15	+	26472758	Raji	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	0.5790045630188105	[74]	[25]	5	hSpCas9	negative selection	537844
38299426	38299449	15	+	26472758	Raji	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	0.7829701770966426	[580]	[231]	7	hSpCas9	negative selection	537845
38349445	38349468	15	+	26472758	Raji	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	-0.05287365928410681	[817]	[182]	0	hSpCas9	negative selection	537846
38322287	38322310	15	+	26472758	Raji	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	-0.36448518650192036	[232]	[41]	-3	hSpCas9	negative selection	537847
38322342	38322365	15	+	26472758	Raji	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	0.2033754482982022	[624]	[166]	2	hSpCas9	negative selection	537848
38322349	38322372	15	-	26472758	Raji	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.6415547004586827	[120]	[17]	-5	hSpCas9	negative selection	537849
38349459	38349482	15	+	26472758	K562	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	0.8945365712080829	[468]	[735]	7	hSpCas9	negative selection	728958
38339804	38339827	15	-	26472758	K562	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	0.6178771231938914	[131]	[170]	5	hSpCas9	negative selection	728959
38253173	38253196	15	+	26472758	K562	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	1.9265223867981347	[66]	[214]	9	hSpCas9	negative selection	728960
38299407	38299430	15	+	26472758	K562	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.8899583787944971	[924]	[1446]	7	hSpCas9	negative selection	728961
38299526	38299549	15	+	26472758	K562	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	1.737333019366432	[150]	[424]	9	hSpCas9	negative selection	728962
38299426	38299449	15	+	26472758	K562	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	0.9554609767671782	[1167]	[1911]	7	hSpCas9	negative selection	728963
38349445	38349468	15	+	26472758	K562	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.747873547251874	[1510]	[2141]	6	hSpCas9	negative selection	728964
38322287	38322310	15	+	26472758	K562	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	0.99874366595424	[379]	[640]	8	hSpCas9	negative selection	728965
38322342	38322365	15	+	26472758	K562	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	1.0524966239516036	[854]	[1496]	8	hSpCas9	negative selection	728966
38322349	38322372	15	-	26472758	K562	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	1.1589832511603866	[199]	[376]	8	hSpCas9	negative selection	728967
38253173	38253196	15	+	26627737	DLD1	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	1.4865481713485766	[252]	[165,224,266]	9	hSpCas9	negative selection	790310
38299437	38299460	15	-	26627737	DLD1	viability	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	0.97281056563791	[723]	[380,553,407]	8	hSpCas9	negative selection	790311
38349437	38349460	15	-	26627737	DLD1	viability	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.44027078282907484	[982]	[449,345,446]	4	hSpCas9	negative selection	790312
38351529	38351552	15	+	26627737	DLD1	viability	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.21601739800271869	[962]	[217,422,402]	2	hSpCas9	negative selection	790313
38351607	38351630	15	-	26627737	DLD1	viability	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	0.5582648000831172	[979]	[397,484,468]	5	hSpCas9	negative selection	790314
38253173	38253196	15	+	26627737	GBM cells	viability after 5 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.016552614902646548	[231]	[103,141]	0	hSpCas9	negative selection	872625
38299437	38299460	15	-	26627737	GBM cells	viability after 5 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.7726642681414515	[531]	[181,151]	-8	hSpCas9	negative selection	872626
38349437	38349460	15	-	26627737	GBM cells	viability after 5 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.13144830664274743	[485]	[300,269]	2	hSpCas9	negative selection	872627
38351529	38351552	15	+	26627737	GBM cells	viability after 5 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.17308883832467964	[343]	[181,233]	2	hSpCas9	negative selection	872628
38351607	38351630	15	-	26627737	GBM cells	viability after 5 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-0.3139933377873236	[378]	[161,164]	-5	hSpCas9	negative selection	872629
38253173	38253196	15	+	26627737	GBM cells	viability after 13 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.2864964803972974	[231]	[100,104]	-3	hSpCas9	negative selection	954940
38299437	38299460	15	-	26627737	GBM cells	viability after 13 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.33244766192374275	[531]	[231,226]	-4	hSpCas9	negative selection	954941
38349437	38349460	15	-	26627737	GBM cells	viability after 13 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.3894333199171074	[485]	[399,300]	5	hSpCas9	negative selection	954942
38351529	38351552	15	+	26627737	GBM cells	viability after 13 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.23154546830855577	[343]	[222,215]	3	hSpCas9	negative selection	954943
38351607	38351630	15	-	26627737	GBM cells	viability after 13 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-0.5219298969445486	[378]	[156,131]	-6	hSpCas9	negative selection	954944
38253173	38253196	15	+	26627737	GBM cells	viability after 21 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.14710925424412002	[231]	[117,109]	-1	hSpCas9	negative selection	1037255
38299437	38299460	15	-	26627737	GBM cells	viability after 21 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.4883151817879795	[531]	[216,195]	-4	hSpCas9	negative selection	1037256
38349437	38349460	15	-	26627737	GBM cells	viability after 21 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.3148287341096063	[485]	[341,315]	3	hSpCas9	negative selection	1037257
38351529	38351552	15	+	26627737	GBM cells	viability after 21 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.46102696782659675	[343]	[262,251]	5	hSpCas9	negative selection	1037258
38351607	38351630	15	-	26627737	GBM cells	viability after 21 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-0.46794379834147837	[378]	[151,145]	-4	hSpCas9	negative selection	1037259
38253173	38253196	15	+	26627737	RPE1	viability after 9 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.6447992649363534	[718]	[323,387]	4	hSpCas9	negative selection	1119570
38299437	38299460	15	-	26627737	RPE1	viability after 9 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	2.7383830708783248	[421]	[668,1155]	9	hSpCas9	negative selection	1119571
38349437	38349460	15	-	26627737	RPE1	viability after 9 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	1.4577795601793992	[756]	[612,699]	7	hSpCas9	negative selection	1119572
38351529	38351552	15	+	26627737	RPE1	viability after 9 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	1.7117310903333944	[719]	[564,961]	8	hSpCas9	negative selection	1119573
38351607	38351630	15	-	26627737	RPE1	viability after 9 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	1.2429719153351713	[856]	[772,456]	7	hSpCas9	negative selection	1119574
38253173	38253196	15	+	26627737	RPE1	viability after 12 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.6904761454656466	[718]	[302,320]	4	hSpCas9	negative selection	1201885
38299437	38299460	15	-	26627737	RPE1	viability after 12 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	2.9649649920493335	[421]	[808,965]	9	hSpCas9	negative selection	1201886
38349437	38349460	15	-	26627737	RPE1	viability after 12 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	1.6020903564893094	[756]	[665,565]	8	hSpCas9	negative selection	1201887
38351529	38351552	15	+	26627737	RPE1	viability after 12 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	1.7392019460700816	[719]	[655,634]	8	hSpCas9	negative selection	1201888
38351607	38351630	15	-	26627737	RPE1	viability after 12 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	0.9481183929548688	[856]	[485,399]	6	hSpCas9	negative selection	1201889
38253173	38253196	15	+	26627737	RPE1	viability after 15 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.47368442137379446	[718]	[285,278]	3	hSpCas9	negative selection	1284200
38299437	38299460	15	-	26627737	RPE1	viability after 15 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	3.083091626026793	[421]	[948,1071]	9	hSpCas9	negative selection	1284201
38349437	38349460	15	-	26627737	RPE1	viability after 15 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	1.8035815509380184	[756]	[745,748]	8	hSpCas9	negative selection	1284202
38351529	38351552	15	+	26627737	RPE1	viability after 15 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	1.7016576413549374	[719]	[690,634]	8	hSpCas9	negative selection	1284203
38351607	38351630	15	-	26627737	RPE1	viability after 15 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	1.5792095759215738	[856]	[983,473]	8	hSpCas9	negative selection	1284204
38253173	38253196	15	+	26627737	RPE1	viability after 18 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.6040205532703323	[718]	[248,343]	4	hSpCas9	negative selection	1366515
38299437	38299460	15	-	26627737	RPE1	viability after 18 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	3.323986829251372	[421]	[993,1296]	9	hSpCas9	negative selection	1366516
38349437	38349460	15	-	26627737	RPE1	viability after 18 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	1.7054411533942604	[756]	[556,782]	8	hSpCas9	negative selection	1366517
38351529	38351552	15	+	26627737	RPE1	viability after 18 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	1.595241506912458	[719]	[370,817]	8	hSpCas9	negative selection	1366518
38351607	38351630	15	-	26627737	RPE1	viability after 18 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	1.6744570373444403	[856]	[817,652]	8	hSpCas9	negative selection	1366519
38253173	38253196	15	+	26627737	HeLa	viability after 8 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.09524292999735745	[409]	[298,225,15]	-1	hSpCas9	negative selection	1448830
38299437	38299460	15	-	26627737	HeLa	viability after 8 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	0.09318896468645632	[675]	[319,342,281]	0	hSpCas9	negative selection	1448831
38349437	38349460	15	-	26627737	HeLa	viability after 8 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.31077480855312445	[784]	[692,267,372]	3	hSpCas9	negative selection	1448832
38351529	38351552	15	+	26627737	HeLa	viability after 8 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.24706837512952584	[591]	[435,265,247]	2	hSpCas9	negative selection	1448833
38351607	38351630	15	-	26627737	HeLa	viability after 8 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	0.7747216833857979	[247]	[193,281,86]	6	hSpCas9	negative selection	1448834
38253173	38253196	15	+	26627737	HeLa	viability after 12 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.5373484514440272	[409]	[140,87,124]	-5	hSpCas9	negative selection	1531145
38299437	38299460	15	-	26627737	HeLa	viability after 12 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.2087406939506381	[675]	[234,288,195]	-2	hSpCas9	negative selection	1531146
38349437	38349460	15	-	26627737	HeLa	viability after 12 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.11817022000277577	[784]	[339,464,238]	1	hSpCas9	negative selection	1531147
38351529	38351552	15	+	26627737	HeLa	viability after 12 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.19220918628131634	[591]	[154,344,327]	1	hSpCas9	negative selection	1531148
38351607	38351630	15	-	26627737	HeLa	viability after 12 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	0.8237465815946391	[247]	[257,128,164]	6	hSpCas9	negative selection	1531149
38253173	38253196	15	+	26627737	HeLa	viability after 15 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.7268560782370397	[409]	[436,217,162]	6	hSpCas9	negative selection	1613460
38299437	38299460	15	-	26627737	HeLa	viability after 15 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.3224210001221987	[675]	[54,234,384]	-3	hSpCas9	negative selection	1613461
38349437	38349460	15	-	26627737	HeLa	viability after 15 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	-0.3233951762623515	[784]	[131,389,244]	-3	hSpCas9	negative selection	1613462
38351529	38351552	15	+	26627737	HeLa	viability after 15 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.301732187790555	[591]	[411,128,352]	2	hSpCas9	negative selection	1613463
38351607	38351630	15	-	26627737	HeLa	viability after 15 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	0.5587803834392353	[247]	[172,85,189]	4	hSpCas9	negative selection	1613464
38253173	38253196	15	+	26627737	HeLa	viability after 18 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.7422904311474915	[409]	[300,177,162]	6	hSpCas9	negative selection	1695775
38299437	38299460	15	-	26627737	HeLa	viability after 18 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.32097941998652085	[675]	[36,194,384]	-3	hSpCas9	negative selection	1695776
38349437	38349460	15	-	26627737	HeLa	viability after 18 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	-0.2943921158931394	[784]	[100,319,244]	-3	hSpCas9	negative selection	1695777
38351529	38351552	15	+	26627737	HeLa	viability after 18 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.28846152308746686	[591]	[262,116,352]	2	hSpCas9	negative selection	1695778
38351607	38351630	15	-	26627737	HeLa	viability after 18 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	0.567503600678772	[247]	[117,70,189]	4	hSpCas9	negative selection	1695779
38253173	38253196	15	+	26627737	HCT116	viability after 6 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-1.5519441453213578	[488]	[51,11]	-7	hSpCas9	negative selection	1778090
38299437	38299460	15	-	26627737	HCT116	viability after 6 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	0.1392842005499979	[1003]	[236,138]	0	hSpCas9	negative selection	1778091
38349437	38349460	15	-	26627737	HCT116	viability after 6 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	1.0103697727681211	[1377]	[369,472]	5	hSpCas9	negative selection	1778092
38351529	38351552	15	+	26627737	HCT116	viability after 6 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.24271495869792914	[1236]	[193,249]	1	hSpCas9	negative selection	1778093
38351607	38351630	15	-	26627737	HCT116	viability after 6 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-0.3931644472078027	[801]	[202,36]	-2	hSpCas9	negative selection	1778094
38253173	38253196	15	+	26627737	HCT116	viability after 8 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.2799677933980971	[260]	[152,156,212]	3	hSpCas9	negative selection	1860405
38299437	38299460	15	-	26627737	HCT116	viability after 8 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	0.282185262537454	[444]	[329,257,306]	3	hSpCas9	negative selection	1860406
38349437	38349460	15	-	26627737	HCT116	viability after 8 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.32692979817221357	[427]	[301,241,342]	3	hSpCas9	negative selection	1860407
38351529	38351552	15	+	26627737	HCT116	viability after 8 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.34051767302141894	[370]	[224,295,254]	3	hSpCas9	negative selection	1860408
38351607	38351630	15	-	26627737	HCT116	viability after 8 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-0.8778916404638497	[533]	[113,78,284]	-8	hSpCas9	negative selection	1860409
38253173	38253196	15	+	26627737	HCT116	viability after 9 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.7185179563845023	[488]	[75,81]	-5	hSpCas9	negative selection	1942720
38299437	38299460	15	-	26627737	HCT116	viability after 9 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.8272024941010196	[1003]	[49,230]	-5	hSpCas9	negative selection	1942721
38349437	38349460	15	-	26627737	HCT116	viability after 9 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	-0.3512357148097266	[1377]	[536,91]	-2	hSpCas9	negative selection	1942722
38351529	38351552	15	+	26627737	HCT116	viability after 9 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	-0.03164615757375633	[1236]	[297,342]	0	hSpCas9	negative selection	1942723
38351607	38351630	15	-	26627737	HCT116	viability after 9 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-0.6835749260478832	[801]	[277,18]	-5	hSpCas9	negative selection	1942724
38253173	38253196	15	+	26627737	HCT116	viability after 12 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.07775985862760107	[260]	[146,195,46]	-1	hSpCas9	negative selection	2025035
38299437	38299460	15	-	26627737	HCT116	viability after 12 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	0.3357831457133562	[444]	[258,269,358]	3	hSpCas9	negative selection	2025036
38349437	38349460	15	-	26627737	HCT116	viability after 12 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.3113969962694827	[427]	[208,299,334]	3	hSpCas9	negative selection	2025037
38351529	38351552	15	+	26627737	HCT116	viability after 12 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.43812463914536764	[370]	[293,311,184]	4	hSpCas9	negative selection	2025038
38351607	38351630	15	-	26627737	HCT116	viability after 12 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-0.5617599335837946	[533]	[270,96,192]	-6	hSpCas9	negative selection	2025039
38253173	38253196	15	+	26627737	HCT116	viability after 15 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.22539021169364457	[260]	[272,62,66]	-2	hSpCas9	negative selection	2107350
38299437	38299460	15	-	26627737	HCT116	viability after 15 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	0.1500320566399217	[444]	[230,303,308]	1	hSpCas9	negative selection	2107351
38349437	38349460	15	-	26627737	HCT116	viability after 15 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.15568757646015674	[427]	[337,197,292]	1	hSpCas9	negative selection	2107352
38351529	38351552	15	+	26627737	HCT116	viability after 15 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.4153886560917049	[370]	[255,388,204]	4	hSpCas9	negative selection	2107353
38351607	38351630	15	-	26627737	HCT116	viability after 15 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-0.7943233772117342	[533]	[232,99,203]	-7	hSpCas9	negative selection	2107354
38253173	38253196	15	+	26627737	HCT116	viability after 18 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.11584011517272394	[260]	[228,55,65]	-1	hSpCas9	negative selection	2189665
38299437	38299460	15	-	26627737	HCT116	viability after 18 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	0.36824609083328597	[444]	[176,216,450]	3	hSpCas9	negative selection	2189666
38349437	38349460	15	-	26627737	HCT116	viability after 18 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.14348764078914755	[427]	[292,164,231]	1	hSpCas9	negative selection	2189667
38351529	38351552	15	+	26627737	HCT116	viability after 18 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.6260364300609214	[370]	[250,410,153]	5	hSpCas9	negative selection	2189668
38351607	38351630	15	-	26627737	HCT116	viability after 18 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-0.8116120746515105	[533]	[109,155,175]	-6	hSpCas9	negative selection	2189669
38253173	38253196	15	+	24336569	HL60	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.3452719200338217	[782]	[2104]	3	hSpCas9	negative selection	2297151
38253179	38253202	15	+	24336569	HL60	viability	GGGAAAGATGAGCGAGGAGACGG	SPRED1	ENSG00000166068	-0.48363542414978566	[706]	[1069]	-4	hSpCas9	negative selection	2297152
38299379	38299402	15	+	24336569	HL60	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.5067008321306039	[749]	[2254]	4	hSpCas9	negative selection	2297153
38299404	38299427	15	+	24336569	HL60	viability	ATGACCCGAGATGACTCAAGTGG	SPRED1	ENSG00000166068	0.365411346141308	[576]	[1572]	3	hSpCas9	negative selection	2297154
38299409	38299432	15	-	24336569	HL60	viability	ATCCACCACTTGAGTCATCTCGG	SPRED1	ENSG00000166068	0.2590454200001916	[215]	[546]	2	hSpCas9	negative selection	2297155
38299422	38299445	15	+	24336569	HL60	viability	AGTGGTGGATGGTTACCACTTGG	SPRED1	ENSG00000166068	2.4481833512160605	[143]	[1662]	9	hSpCas9	negative selection	2297156
38299431	38299454	15	+	24336569	HL60	viability	TGGTTACCACTTGGAGGGAGTGG	SPRED1	ENSG00000166068	-0.05106485032472469	[586]	[1198]	0	hSpCas9	negative selection	2297157
38299437	38299460	15	-	24336569	HL60	viability	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	1.573342388706369	[83]	[528]	9	hSpCas9	negative selection	2297158
38299469	38299492	15	+	24336569	HL60	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	-1.1293656458405386	[887]	[858]	-8	hSpCas9	negative selection	2297159
38299479	38299502	15	+	24336569	HL60	viability	GTCCCTCATCAGGAAGAGAATGG	SPRED1	ENSG00000166068	0.5658275333854201	[150]	[472]	5	hSpCas9	negative selection	2297160
38253173	38253196	15	+	24336569	KBM7	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.9331455962298962	[475]	[2478]	7	hSpCas9	negative selection	2364328
38253179	38253202	15	+	24336569	KBM7	viability	GGGAAAGATGAGCGAGGAGACGG	SPRED1	ENSG00000166068	0.7566468352378195	[410]	[1893]	6	hSpCas9	negative selection	2364329
38299379	38299402	15	+	24336569	KBM7	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.42708832541637665	[660]	[2423]	4	hSpCas9	negative selection	2364330
38299404	38299427	15	+	24336569	KBM7	viability	ATGACCCGAGATGACTCAAGTGG	SPRED1	ENSG00000166068	0.6487891979233489	[303]	[1299]	6	hSpCas9	negative selection	2364331
38299409	38299432	15	-	24336569	KBM7	viability	ATCCACCACTTGAGTCATCTCGG	SPRED1	ENSG00000166068	0.4062704362515053	[204]	[740]	4	hSpCas9	negative selection	2364332
38299422	38299445	15	+	24336569	KBM7	viability	AGTGGTGGATGGTTACCACTTGG	SPRED1	ENSG00000166068	1.2839443125490757	[331]	[2204]	9	hSpCas9	negative selection	2364333
38299431	38299454	15	+	24336569	KBM7	viability	TGGTTACCACTTGGAGGGAGTGG	SPRED1	ENSG00000166068	1.2523442592711205	[214]	[1396]	8	hSpCas9	negative selection	2364334
38299437	38299460	15	-	24336569	KBM7	viability	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	1.2387440191315147	[157]	[1016]	8	hSpCas9	negative selection	2364335
38299469	38299492	15	+	24336569	KBM7	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.3132331395716915	[377]	[1280]	3	hSpCas9	negative selection	2364336
38299479	38299502	15	+	24336569	KBM7	viability	GTCCCTCATCAGGAAGAGAATGG	SPRED1	ENSG00000166068	0.3237379024081006	[248]	[849]	3	hSpCas9	negative selection	2364337
38310189	38310212	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGCGCAGTGGCGCGATCTCGG	SPRED1	ENSG00000166068	-0.814608194487327	[84,35]	[10,2]	-4	dCas9-VP64	positive selection	2398674
38259472	38259495	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAAGAGGATCACTTGAGCCAAG	SPRED1	ENSG00000166068	0.169734143386715	[57,44]	[12,10]	0	dCas9-VP64	positive selection	2416795
38310243	38310266	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGGCTGAGGCAGGAGAAAAG	SPRED1	ENSG00000166068	-0.8896445471743792	[26,0]	[0,0]	-5	dCas9-VP64	positive selection	2422140
38252662	38252685	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGGTGGGGTGGGCTCCGGCAGG	SPRED1	ENSG00000166068	2.075182399609119	[175,23]	[4,183]	7	dCas9-VP64	positive selection	2467385
38252759	38252782	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTTCCCTCAGGGATGCGGCGAGG	SPRED1	ENSG00000166068	-1.047987569484779	[22,73]	[1,7]	-6	dCas9-VP64	positive selection	2467386
38252738	38252761	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGGAAGCAGAGCTCCGCTCGG	SPRED1	ENSG00000166068	-1.474301807310133	[13,182]	[3,10]	-8	dCas9-VP64	positive selection	2467387
38310189	38310212	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGCGCAGTGGCGCGATCTCGG	SPRED1	ENSG00000166068	-1.763356426520778	[237,164]	[17,19]	-9	dCas9-VP64	positive selection	2493929
38259472	38259495	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAAGAGGATCACTTGAGCCAAG	SPRED1	ENSG00000166068	-0.04478500742304492	[42,58]	[7,21]	0	dCas9-VP64	positive selection	2512050
38310243	38310266	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGGCTGAGGCAGGAGAAAAG	SPRED1	ENSG00000166068	0.4958448470370793	[21,20]	[10,7]	4	dCas9-VP64	positive selection	2517395
38252662	38252685	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGGTGGGGTGGGCTCCGGCAGG	SPRED1	ENSG00000166068	-0.0188610287926414	[38,68]	[10,22]	0	dCas9-VP64	positive selection	2562640
38252759	38252782	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTTCCCTCAGGGATGCGGCGAGG	SPRED1	ENSG00000166068	-0.04564351008557077	[74,99]	[27,25]	0	dCas9-VP64	positive selection	2562641
38252738	38252761	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGGAAGCAGAGCTCCGCTCGG	SPRED1	ENSG00000166068	-0.6545017992680624	[55,44]	[7,11]	-6	dCas9-VP64	positive selection	2562642
38299423	38299446	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTGGTGGATGGTTACCACTTGG	SPRED1	ENSG00000166068	0.23319499483614195	[4,3]	[4,3]	5	hSpCas9	positive selection	3023494
38299437	38299460	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	0.08813405194969387	[4,4]	[4,3]	1	hSpCas9	positive selection	3023495
38322303	38322326	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	-0.059743884381791845	[4,4]	[4,2]	-1	hSpCas9	positive selection	3023496
38299520	38299543	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCCCTGAGTCGCTCTCCACGG	SPRED1	ENSG00000166068	0.1277571485649927	[4,4]	[4,4]	2	hSpCas9	positive selection	3023497
38299423	38299446	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTGGTGGATGGTTACCACTTGG	SPRED1	ENSG00000166068	-0.30345241518863236	[4,4]	[3,0]	-4	hSpCas9	positive selection	3091352
38299437	38299460	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.17608633862067094	[4,4]	[4,1]	-3	hSpCas9	positive selection	3091353
38322303	38322326	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	0.2355323038907906	[4,4]	[3,3]	4	hSpCas9	positive selection	3091354
38299520	38299543	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCCCTGAGTCGCTCTCCACGG	SPRED1	ENSG00000166068	-0.1054388531298367	[4,4]	[4,1]	-1	hSpCas9	positive selection	3091355
38322375	38322398		+	24336571	A375	resistance to PLX after 7 days	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.9310447965152779	[2,2]	[4,5]	9	hSpCas9	positive selection	3147252
38299503	38299526		+	24336571	A375	resistance to PLX after 7 days	TGTGCTGACTTTTTTATCCGTGG	SPRED1	ENSG00000166068	-0.3218330781691844	[23,26]	[19,19]	-8	hSpCas9	positive selection	3147253
38299379	38299402		+	24336571	A375	resistance to PLX after 7 days	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	1.4577484122820163	[14,18]	[45,48]	9	hSpCas9	positive selection	3147254
38322375	38322398		+	24336571	A375	resistance to PLX after 14 days	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	1.9180741939742771	[2,2]	[5,5]	9	hSpCas9	positive selection	3205045
38299503	38299526		+	24336571	A375	resistance to PLX after 14 days	TGTGCTGACTTTTTTATCCGTGG	SPRED1	ENSG00000166068	-0.5079519708819549	[22,22]	[7,6]	-6	hSpCas9	positive selection	3205046
38299379	38299402		+	24336571	A375	resistance to PLX after 14 days	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	3.8184689750772565	[16,18]	[120,119]	9	hSpCas9	positive selection	3205047
38322375	38322398		+	24336571	A375	viability after 7 days	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.04038783333833784	[2]	[2,2]	0	hSpCas9	negative selection	3262838
38299503	38299526		+	24336571	A375	viability after 7 days	TGTGCTGACTTTTTTATCCGTGG	SPRED1	ENSG00000166068	0.4317600772369693	[19]	[23,26]	6	hSpCas9	negative selection	3262839
38299379	38299402		+	24336571	A375	viability after 7 days	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.11560465565802808	[16]	[14,18]	1	hSpCas9	negative selection	3262840
38322375	38322398		+	24336571	A375	viability after 14 days	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.2127894220097668	[2]	[2,2]	2	hSpCas9	negative selection	3320631
38299503	38299526		+	24336571	A375	viability after 14 days	TGTGCTGACTTTTTTATCCGTGG	SPRED1	ENSG00000166068	0.33416529480013524	[19]	[22,22]	4	hSpCas9	negative selection	3320632
38299379	38299402		+	24336571	A375	viability after 14 days	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.20060696006240042	[16]	[16,18]	2	hSpCas9	negative selection	3320633
38339843	38339866	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.8873320313860472	[282,282]	[0,0]	-6	hSpCas9	positive selection	3394789
38339874	38339897	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.8616148612776724	[277,277]	[0,0]	-6	hSpCas9	positive selection	3394790
38322349	38322372	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	1.1912370209880627	[66,66]	[0,0]	5	hSpCas9	positive selection	3394791
38299422	38299445	15	+	26780180	HT29	viability (Avana library 4 designs)	AGTGGTGGATGGTTACCACTTGG	SPRED1	ENSG00000166068	-0.0251607544834684	[]	[]	0	hSpCas9	negative selection	3462124
38299437	38299460	15	-	26780180	HT29	viability (Avana library 4 designs)	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.784555964587771	[]	[]	-9	hSpCas9	negative selection	3462125
38322303	38322326	15	-	26780180	HT29	viability (Avana library 4 designs)	TCTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	-0.800887198015997	[]	[]	-9	hSpCas9	negative selection	3462126
38299520	38299543	15	-	26780180	HT29	viability (Avana library 4 designs)	TGTCCCTGAGTCGCTCTCCACGG	SPRED1	ENSG00000166068	-0.919683084056499	[]	[]	-9	hSpCas9	negative selection	3462127
38299437	38299460	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	0.913622185550077	[]	[]	1	hSpCas9	negative selection	3563500
38299520	38299543	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCCCTGAGTCGCTCTCCACGG	SPRED1	ENSG00000166068	0.856828562688457	[]	[]	1	hSpCas9	negative selection	3563501
38299422	38299445	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGGTGGATGGTTACCACTTGG	SPRED1	ENSG00000166068	4.32089093227937	[]	[]	7	hSpCas9	negative selection	3563502
38322303	38322326	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	-0.696520216132124	[]	[]	-1	hSpCas9	negative selection	3563503
38299407	38299430	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	3.495999587657	[]	[]	5	hSpCas9	negative selection	3563504
38339842	38339865	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGGCATTCAGATCTTCAAAGGG	SPRED1	ENSG00000166068	-1.26177504231556	[]	[]	-1	hSpCas9	negative selection	3563505
38299437	38299460	15	-	26780180	A375	viability (Avana lentiGuide)	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-3.83117373343804	[]	[]	-6	hSpCas9	negative selection	3672159
38299520	38299543	15	-	26780180	A375	viability (Avana lentiGuide)	TGTCCCTGAGTCGCTCTCCACGG	SPRED1	ENSG00000166068	0.210376929187897	[]	[]	0	hSpCas9	negative selection	3672160
38299422	38299445	15	+	26780180	A375	viability (Avana lentiGuide)	AGTGGTGGATGGTTACCACTTGG	SPRED1	ENSG00000166068	-0.22696056130259	[]	[]	0	hSpCas9	negative selection	3672161
38322303	38322326	15	-	26780180	A375	viability (Avana lentiGuide)	TCTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	-6.12259407497895	[]	[]	-9	hSpCas9	negative selection	3672162
38299407	38299430	15	+	26780180	A375	viability (Avana lentiGuide)	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	1.89560055325516	[]	[]	2	hSpCas9	negative selection	3672163
38339842	38339865	15	-	26780180	A375	viability (Avana lentiGuide)	CTGGCATTCAGATCTTCAAAGGG	SPRED1	ENSG00000166068	-4.18251805721261	[]	[]	-7	hSpCas9	negative selection	3672164
38299437	38299460	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	0.5676780968728545	[5]	[8,7]	9	hSpCas9	positive selection	3780766
38299520	38299543	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCCCTGAGTCGCTCTCCACGG	SPRED1	ENSG00000166068	0.5546074042594697	[5]	[8,7]	9	hSpCas9	positive selection	3780767
38299422	38299445	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGGTGGATGGTTACCACTTGG	SPRED1	ENSG00000166068	0.720283715911523	[5]	[8,8]	9	hSpCas9	positive selection	3780768
38322303	38322326	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	-0.2318039181204487	[5]	[3,4]	-4	hSpCas9	positive selection	3780769
38299407	38299430	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.7026932092651939	[4]	[8,7]	9	hSpCas9	positive selection	3780770
38339842	38339865	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGGCATTCAGATCTTCAAAGGG	SPRED1	ENSG00000166068	-0.059221583223323125	[5]	[5,4]	-1	hSpCas9	positive selection	3780771
38299437	38299460	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	0.4354775943978462	[5]	[6,6]	9	hSpCas9	positive selection	3889373
38299520	38299543	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCCCTGAGTCGCTCTCCACGG	SPRED1	ENSG00000166068	0.1285533257579831	[6]	[5,5]	3	hSpCas9	positive selection	3889374
38299422	38299445	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGGTGGATGGTTACCACTTGG	SPRED1	ENSG00000166068	0.4565437426637749	[5]	[7,5]	9	hSpCas9	positive selection	3889375
38322303	38322326	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	0.35887966561823303	[5]	[6,5]	9	hSpCas9	positive selection	3889376
38299407	38299430	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.5746491956838987	[4]	[7,5]	9	hSpCas9	positive selection	3889377
38339842	38339865	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGGCATTCAGATCTTCAAAGGG	SPRED1	ENSG00000166068	0.45689975550116824	[5]	[6,6]	9	hSpCas9	positive selection	3889378
38322375	38322398	15	+	26780180	A375	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.602554860562649	[]	[]	2	hSpCas9	negative selection	3999138
38339874	38339897	15	+	26780180	A375	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	1.97254670609474	[]	[]	9	hSpCas9	negative selection	3999139
38322349	38322372	15	-	26780180	A375	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	1.4051467829488	[]	[]	7	hSpCas9	negative selection	3999140
38339843	38339866	15	-	26780180	A375	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	1.32839543307353	[]	[]	7	hSpCas9	negative selection	3999141
38299469	38299492	15	+	26780180	A375	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	1.29792351467285	[]	[]	7	hSpCas9	negative selection	3999142
38299379	38299402	15	+	26780180	A375	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	1.52775548618029	[]	[]	8	hSpCas9	negative selection	3999143
38322375	38322398	15	+	26780180	HT29	viability (GeCKOv2 library)	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.553835470301097	[]	[]	1	hSpCas9	negative selection	4107104
38339874	38339897	15	+	26780180	HT29	viability (GeCKOv2 library)	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	1.12801992109842	[]	[]	5	hSpCas9	negative selection	4107105
38322349	38322372	15	-	26780180	HT29	viability (GeCKOv2 library)	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	1.77850081582776	[]	[]	8	hSpCas9	negative selection	4107106
38339843	38339866	15	-	26780180	HT29	viability (GeCKOv2 library)	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.1147229943046	[]	[]	0	hSpCas9	negative selection	4107107
38299469	38299492	15	+	26780180	HT29	viability (GeCKOv2 library)	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.376770246417076	[]	[]	1	hSpCas9	negative selection	4107108
38299379	38299402	15	+	26780180	HT29	viability (GeCKOv2 library)	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.181657285627766	[]	[]	0	hSpCas9	negative selection	4107109
38322375	38322398	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	1.064761948471646	[1]	[3,2]	9	hSpCas9	positive selection	4173431
38299503	38299526	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTGCTGACTTTTTTATCCGTGG	SPRED1	ENSG00000166068	-0.015999979102340134	[4]	[3,2]	0	hSpCas9	positive selection	4173432
38299379	38299402	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	1.00128646884398	[3]	[4,6]	9	hSpCas9	positive selection	4173433
38322375	38322398	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	1.7193212823560369	[1]	[0,0,1,4]	9	hSpCas9	positive selection	4237453
38299503	38299526	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTGCTGACTTTTTTATCCGTGG	SPRED1	ENSG00000166068	0.6079621475836655	[3]	[3,2,5,0]	4	hSpCas9	positive selection	4237454
38299379	38299402	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	2.0055782426483315	[4]	[8,8,6,7]	9	hSpCas9	positive selection	4237455
38322375	38322398	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.4333827121052135	[0]	[1,0]	8	hSpCas9	positive selection	4300414
38299379	38299402	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.5663934226441961	[2]	[4,2]	9	hSpCas9	positive selection	4300415
38299469	38299492	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.8357803157999608	[3]	[5,4]	9	hSpCas9	positive selection	4300416
38339843	38339866	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.3134611500974662	[3]	[4,2]	6	hSpCas9	positive selection	4364669
38339874	38339897	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.3601608599170367	[3]	[2,1]	-6	hSpCas9	positive selection	4364670
38322349	38322372	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.3292659562864201	[2]	[3,1]	6	hSpCas9	positive selection	4364671
38299518	38299540	15	+	27760321	OCIAML3	viability	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	-0.2208588888271922	[504,402]	[212,419]	-2	hSpCas9	negative selection	4442905
38322303	38322325	15	-	27760321	OCIAML3	viability	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	0.9047533794006689	[345,278]	[349,591]	9	hSpCas9	negative selection	4442906
38339756	38339778	15	-	27760321	OCIAML3	viability	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	0.07552275646082385	[174,153]	[133,136]	0	hSpCas9	negative selection	4442907
38349420	38349442	15	+	27760321	OCIAML3	viability	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	0.9436286260013979	[867,676]	[1071,1260]	9	hSpCas9	negative selection	4442908
38349473	38349495	15	+	27760321	OCIAML3	viability	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	-0.674833674672275	[353,270]	[78,246]	-6	hSpCas9	negative selection	4442909
38299518	38299540	15	+	27760321	OCIAML2	viability	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	0.8082343543693643	[504,402]	[533,777]	9	hSpCas9	negative selection	4526368
38322303	38322325	15	-	27760321	OCIAML2	viability	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	1.0129433613122238	[345,278]	[477,545]	9	hSpCas9	negative selection	4526369
38339756	38339778	15	-	27760321	OCIAML2	viability	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	0.298068244264849	[174,153]	[161,164]	4	hSpCas9	negative selection	4526370
38349420	38349442	15	+	27760321	OCIAML2	viability	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	0.6583355254252191	[867,676]	[840,1161]	8	hSpCas9	negative selection	4526371
38349473	38349495	15	+	27760321	OCIAML2	viability	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	-0.014025603269561981	[353,270]	[203,306]	0	hSpCas9	negative selection	4526372
38299518	38299540	15	+	27760321	MV411	viability	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	0.7295022661414959	[504,402]	[251,856]	5	hSpCas9	negative selection	4609831
38322303	38322325	15	-	27760321	MV411	viability	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	0.1257617348849785	[345,278]	[176,293]	0	hSpCas9	negative selection	4609832
38339756	38339778	15	-	27760321	MV411	viability	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	-0.6470038002563623	[174,153]	[53,91]	-4	hSpCas9	negative selection	4609833
38349420	38349442	15	+	27760321	MV411	viability	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	0.46901006740167783	[867,676]	[657,764]	3	hSpCas9	negative selection	4609834
38349473	38349495	15	+	27760321	MV411	viability	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	0.19629360785842848	[353,270]	[84,458]	1	hSpCas9	negative selection	4609835
38299518	38299540	15	+	27760321	HL60	viability	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	0.038917234374378155	[504,402]	[336,422]	0	hSpCas9	negative selection	4693294
38322303	38322325	15	-	27760321	HL60	viability	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	0.5022676617080674	[345,278]	[378,338]	6	hSpCas9	negative selection	4693295
38339756	38339778	15	-	27760321	HL60	viability	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	1.242074664226676	[174,153]	[357,273]	9	hSpCas9	negative selection	4693296
38349420	38349442	15	+	27760321	HL60	viability	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	0.6682104720522953	[867,676]	[859,1139]	7	hSpCas9	negative selection	4693297
38349473	38349495	15	+	27760321	HL60	viability	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	0.6553570874022059	[353,270]	[431,363]	7	hSpCas9	negative selection	4693298
38299518	38299540	15	+	27760321	HT1080	viability	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	0.09440231655186966	[402,314]	[177,124]	0	hSpCas9	negative selection	4776757
38322303	38322325	15	-	27760321	HT1080	viability	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	1.547588964597262	[278,217]	[139,452]	8	hSpCas9	negative selection	4776758
38339756	38339778	15	-	27760321	HT1080	viability	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	1.2593155073299769	[153,119]	[143,115]	6	hSpCas9	negative selection	4776759
38349420	38349442	15	+	27760321	HT1080	viability	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	1.0209439977906851	[676,527]	[413,566]	5	hSpCas9	negative selection	4776760
38349473	38349495	15	+	27760321	HT1080	viability	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	-0.52797030932332	[270,211]	[39,95]	-2	hSpCas9	negative selection	4776761
38299518	38299540	15	+	27760321	HT29	viability after 7 days	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	0.13996699031398924	[402,314]	[497,590,436]	2	hSpCas9	negative selection	4860220
38322303	38322325	15	-	27760321	HT29	viability after 7 days	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	-0.17045203701074607	[278,217]	[460,271,147]	-2	hSpCas9	negative selection	4860221
38339756	38339778	15	-	27760321	HT29	viability after 7 days	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	-0.7027113754454117	[153,119]	[184,91,59]	-7	hSpCas9	negative selection	4860222
38349420	38349442	15	+	27760321	HT29	viability after 7 days	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	-0.10342951447615678	[676,527]	[744,653,764]	-1	hSpCas9	negative selection	4860223
38349473	38349495	15	+	27760321	HT29	viability after 7 days	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	0.6029140173614659	[270,211]	[350,349,688]	8	hSpCas9	negative selection	4860224
38299518	38299540	15	+	27760321	HT29	viability after 25 days	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	1.4537297893745598	[402,314]	[1206,1212,923]	9	hSpCas9	negative selection	4943683
38322303	38322325	15	-	27760321	HT29	viability after 25 days	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	0.8696265464475539	[278,217]	[558,436,561]	8	hSpCas9	negative selection	4943684
38339756	38339778	15	-	27760321	HT29	viability after 25 days	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	1.0586305360406703	[153,119]	[417,244,306]	9	hSpCas9	negative selection	4943685
38349420	38349442	15	+	27760321	HT29	viability after 25 days	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	0.6771630932236096	[676,527]	[787,1335,1207]	7	hSpCas9	negative selection	4943686
38349473	38349495	15	+	27760321	HT29	viability after 25 days	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	1.5708400703405432	[270,211]	[931,809,696]	9	hSpCas9	negative selection	4943687
38299518	38299540	15	+	27760321	HT29	viability after 22 days	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	1.1138237203744257	[402,314]	[821,853,1021]	9	hSpCas9	negative selection	5027146
38322303	38322325	15	-	27760321	HT29	viability after 22 days	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	0.7905937644339107	[278,217]	[406,516,569]	8	hSpCas9	negative selection	5027147
38339756	38339778	15	-	27760321	HT29	viability after 22 days	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	0.43649659431024623	[153,119]	[244,193,202]	5	hSpCas9	negative selection	5027148
38349420	38349442	15	+	27760321	HT29	viability after 22 days	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	0.6265602279749881	[676,527]	[1168,1115,936]	7	hSpCas9	negative selection	5027149
38349473	38349495	15	+	27760321	HT29	viability after 22 days	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	1.271264463402272	[270,211]	[597,642,783]	9	hSpCas9	negative selection	5027150
38299518	38299540	15	+	27760321	HT29	viability after 19 days	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	1.4763141005362914	[402,314]	[1001,1776,651]	9	hSpCas9	negative selection	5110609
38322303	38322325	15	-	27760321	HT29	viability after 19 days	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	0.5105138864055141	[278,217]	[410,397,405]	5	hSpCas9	negative selection	5110610
38339756	38339778	15	-	27760321	HT29	viability after 19 days	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	0.5961471760622387	[153,119]	[289,164,259]	6	hSpCas9	negative selection	5110611
38349420	38349442	15	+	27760321	HT29	viability after 19 days	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	0.2863698620921956	[676,527]	[986,982,575]	2	hSpCas9	negative selection	5110612
38349473	38349495	15	+	27760321	HT29	viability after 19 days	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	1.3384018576291823	[270,211]	[867,496,745]	9	hSpCas9	negative selection	5110613
38299518	38299540	15	+	27760321	HT29	viability after 16 days	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	0.9243616024565404	[402,314]	[1058,682,574]	9	hSpCas9	negative selection	5194072
38322303	38322325	15	-	27760321	HT29	viability after 16 days	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	0.48932371121419366	[278,217]	[399,343,428]	5	hSpCas9	negative selection	5194073
38339756	38339778	15	-	27760321	HT29	viability after 16 days	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	0.06828625596850246	[153,119]	[238,100,150]	0	hSpCas9	negative selection	5194074
38349420	38349442	15	+	27760321	HT29	viability after 16 days	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	0.6390688094840328	[676,527]	[725,1217,1169]	7	hSpCas9	negative selection	5194075
38349473	38349495	15	+	27760321	HT29	viability after 16 days	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	1.1444041487049488	[270,211]	[467,587,723]	9	hSpCas9	negative selection	5194076
38299518	38299540	15	+	27760321	HT29	viability after 13 days	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	0.9047532528364314	[402,314]	[791,762,783]	9	hSpCas9	negative selection	5277535
38322303	38322325	15	-	27760321	HT29	viability after 13 days	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	0.2361089817901983	[278,217]	[338,328,349]	3	hSpCas9	negative selection	5277536
38339756	38339778	15	-	27760321	HT29	viability after 13 days	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	0.7427675947201866	[153,119]	[386,272,144]	8	hSpCas9	negative selection	5277537
38349420	38349442	15	+	27760321	HT29	viability after 13 days	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	0.20510595412286003	[676,527]	[683,888,841]	2	hSpCas9	negative selection	5277538
38349473	38349495	15	+	27760321	HT29	viability after 13 days	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	1.120216295289203	[270,211]	[865,306,650]	9	hSpCas9	negative selection	5277539
38299518	38299540	15	+	27760321	HT29	viability after 10 days	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	0.7368434270839306	[402,314]	[643,731,861]	8	hSpCas9	negative selection	5360998
38322303	38322325	15	-	27760321	HT29	viability after 10 days	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	0.09466134993458453	[278,217]	[477,266,248]	1	hSpCas9	negative selection	5360999
38339756	38339778	15	-	27760321	HT29	viability after 10 days	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	-0.42187724558249573	[153,119]	[160,112,108]	-5	hSpCas9	negative selection	5361000
38349420	38349442	15	+	27760321	HT29	viability after 10 days	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	0.02571551048383025	[676,527]	[493,944,860]	0	hSpCas9	negative selection	5361001
38349473	38349495	15	+	27760321	HT29	viability after 10 days	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	0.7223493958767797	[270,211]	[434,433,618]	8	hSpCas9	negative selection	5361002
38299518	38299540	15	+	27760321	MOLM13	viability	ATCCGTGGAGAGCGACTCAGGG	SPRED1	ENSG00000166068	0.6168380258268248	[504,402]	[632,183]	4	hSpCas9	negative selection	5444461
38322303	38322325	15	-	27760321	MOLM13	viability	CTTGTCATCAATCTTCCAGTGG	SPRED1	ENSG00000166068	2.1052375188527694	[345,278]	[667,827]	9	hSpCas9	negative selection	5444462
38339756	38339778	15	-	27760321	MOLM13	viability	TGATCCTTCACTAGAGAACTGG	SPRED1	ENSG00000166068	-0.8874438253785231	[174,153]	[75,27]	-5	hSpCas9	negative selection	5444463
38349420	38349442	15	+	27760321	MOLM13	viability	AGATAACATTTGGTCAGCCAGG	SPRED1	ENSG00000166068	0.5846234454356501	[867,676]	[781,535]	4	hSpCas9	negative selection	5444464
38349473	38349495	15	+	27760321	MOLM13	viability	GTACAGCGGCAAATATCCAAGG	SPRED1	ENSG00000166068	0.9107338420758919	[353,270]	[396,270]	6	hSpCas9	negative selection	5444465
38252647	38252670	15	+	27661255	K562	viability	GCGGCGAGGCGGGAGATGGTGGG	SPRED1	ENSG00000166068	-0.06143687495661987	[331,398]	[300,259]	-2	dCas9-KRAB	negative selection	5514088
38252951	38252974	15	+	27661255	K562	viability	GGAAGAGGCTGGGGTCGCCACGG	SPRED1	ENSG00000166068	0.2026437530337419	[631,864]	[694,674]	7	dCas9-KRAB	negative selection	5514089
38252321	38252344	15	-	27661255	K562	viability	GCTCCTCACGCCCGAGAGAGGGG	SPRED1	ENSG00000166068	-0.48949138890353927	[239,258]	[144,138]	-7	dCas9-KRAB	negative selection	5514090
38252410	38252433	15	-	27661255	K562	viability	GGGGGCAGGATCCCGAGAAGCGG	SPRED1	ENSG00000166068	0.10314570004270218	[890,1176]	[892,873]	3	dCas9-KRAB	negative selection	5514091
38252919	38252942	15	-	27661255	K562	viability	GTGCCCAGCCAAGGGATCCGAGG	SPRED1	ENSG00000166068	-0.5361730129269984	[574,401]	[313,233]	-7	dCas9-KRAB	negative selection	5514092
38253112	38253135	15	-	27661255	K562	viability	GGAGCAACAGCAGCACCGAGGGG	SPRED1	ENSG00000166068	0.18943916855490628	[1425,1626]	[1580,1221]	6	dCas9-KRAB	negative selection	5514093
38322375	38322398	15	+	27260156	BXPC3	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	-0.1051185749003416	[49]	[35,38,51,71]	-2	hSpCas9	negative selection	5572874
38299379	38299402	15	+	27260156	BXPC3	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.07477056077478877	[446]	[440,441,509,593]	1	hSpCas9	negative selection	5572875
38299469	38299492	15	+	27260156	BXPC3	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.4873800640511547	[620]	[752,853,921,1156]	8	hSpCas9	negative selection	5572876
38339843	38339866	15	-	27260156	BXPC3	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.1663810779951922	[668]	[567,740,700,1200]	3	hSpCas9	negative selection	5637129
38339874	38339897	15	+	27260156	BXPC3	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.10009269132793569	[629]	[460,570,683,778]	-2	hSpCas9	negative selection	5637130
38322349	38322372	15	-	27260156	BXPC3	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.16611958421354778	[248]	[230,201,213,287]	-4	hSpCas9	negative selection	5637131
38322375	38322398	15	+	27260156	A673	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.5920419642012993	[49]	[66,127,105,54]	9	hSpCas9	negative selection	5694125
38299379	38299402	15	+	27260156	A673	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.05226553895109691	[446]	[557,545,495,470]	-1	hSpCas9	negative selection	5694126
38299469	38299492	15	+	27260156	A673	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.3988958637643894	[620]	[1056,868,1012,1003]	8	hSpCas9	negative selection	5694127
38339843	38339866	15	-	27260156	A673	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.12376915856716009	[668]	[934,867,882,816]	3	hSpCas9	negative selection	5758380
38339874	38339897	15	+	27260156	A673	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.021168526155985523	[629]	[883,725,637,749]	0	hSpCas9	negative selection	5758381
38322349	38322372	15	-	27260156	A673	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.04047482283850601	[248]	[339,253,248,396]	1	hSpCas9	negative selection	5758382
38322375	38322398	15	+	27260156	A375	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.46984057948771474	[49]	[101,124,53,51]	7	hSpCas9	negative selection	5815376
38299379	38299402	15	+	27260156	A375	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.4173869392483125	[446]	[257,496,457,365]	-5	hSpCas9	negative selection	5815377
38299469	38299492	15	+	27260156	A375	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.3284696788199671	[620]	[993,872,1005,777]	5	hSpCas9	negative selection	5815378
38339843	38339866	15	-	27260156	A375	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.029499486106921102	[668]	[859,699,761,845]	0	hSpCas9	negative selection	5879631
38339874	38339897	15	+	27260156	A375	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.3604376729229135	[629]	[829,1124,998,855]	5	hSpCas9	negative selection	5879632
38322349	38322372	15	-	27260156	A375	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.17860626945457514	[248]	[378,232,394,298]	2	hSpCas9	negative selection	5879633
38322375	38322398	15	+	27260156	COLO741	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	-0.07135510712259618	[49]	[66,57,57]	-1	hSpCas9	negative selection	5936627
38299379	38299402	15	+	27260156	COLO741	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.02874511135517588	[446]	[759,456,546]	0	hSpCas9	negative selection	5936628
38299469	38299492	15	+	27260156	COLO741	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.4810160005750194	[620]	[1198,1028,1099]	8	hSpCas9	negative selection	5936629
38339843	38339866	15	-	27260156	COLO741	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.0135438311570939	[668]	[889,873,782]	0	hSpCas9	negative selection	6000882
38339874	38339897	15	+	27260156	COLO741	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.07157059124371223	[629]	[1026,917,622]	1	hSpCas9	negative selection	6000883
38322349	38322372	15	-	27260156	COLO741	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.016670143782962388	[248]	[245,388,302]	0	hSpCas9	negative selection	6000884
38322375	38322398	15	+	27260156	CAL120	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.19801288815173068	[49]	[62,87,61]	3	hSpCas9	negative selection	6057878
38299379	38299402	15	+	27260156	CAL120	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.17319663044995337	[446]	[714,466,333]	-3	hSpCas9	negative selection	6057879
38299469	38299492	15	+	27260156	CAL120	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.5009265589391625	[620]	[1074,693,1500]	7	hSpCas9	negative selection	6057880
38339843	38339866	15	-	27260156	CAL120	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.34374934798959966	[668]	[1094,1034,1044]	5	hSpCas9	negative selection	6122133
38339874	38339897	15	+	27260156	CAL120	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.026153696000342674	[629]	[969,516,930]	0	hSpCas9	negative selection	6122134
38322349	38322372	15	-	27260156	CAL120	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.07730186797717076	[248]	[511,256,240]	1	hSpCas9	negative selection	6122135
38322375	38322398	15	+	27260156	CADOES1	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	-0.03710685643221767	[49]	[35,54,27,62]	0	hSpCas9	negative selection	6179129
38299379	38299402	15	+	27260156	CADOES1	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.4136852259957915	[446]	[413,285,288,256]	-6	hSpCas9	negative selection	6179130
38299469	38299492	15	+	27260156	CADOES1	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.5524664434794799	[620]	[810,763,713,1108]	8	hSpCas9	negative selection	6179131
38339843	38339866	15	-	27260156	CADOES1	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.13882071876594865	[668]	[556,731,531,434]	-2	hSpCas9	negative selection	6243384
38339874	38339897	15	+	27260156	CADOES1	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.10284849755905406	[629]	[479,659,570,468]	-2	hSpCas9	negative selection	6243385
38322349	38322372	15	-	27260156	CADOES1	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.42366409612880074	[248]	[250,261,381,348]	7	hSpCas9	negative selection	6243386
38322375	38322398	15	+	27260156	EWS502	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.5721732628024823	[49]	[122,49,60,75]	8	hSpCas9	negative selection	6300380
38299379	38299402	15	+	27260156	EWS502	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.44091121782601284	[446]	[458,214,411,296]	-6	hSpCas9	negative selection	6300381
38299469	38299492	15	+	27260156	EWS502	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.23705247906261012	[620]	[663,800,800,849]	4	hSpCas9	negative selection	6300382
38339843	38339866	15	-	27260156	EWS502	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.3386664890520138	[668]	[744,663,1073,1145]	6	hSpCas9	negative selection	6364635
38339874	38339897	15	+	27260156	EWS502	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.08729758876393878	[629]	[404,855,837,770]	1	hSpCas9	negative selection	6364636
38322349	38322372	15	-	27260156	EWS502	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.07250453875861462	[248]	[206,235,305,376]	1	hSpCas9	negative selection	6364637
38322375	38322398	15	+	27260156	EW8	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	-0.7029544368366416	[49]	[32,16,20,29]	-8	hSpCas9	negative selection	6421631
38299379	38299402	15	+	27260156	EW8	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.0003417201306756268	[446]	[803,181,204,331]	0	hSpCas9	negative selection	6421632
38299469	38299492	15	+	27260156	EW8	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.228896336208313	[620]	[623,658,666,398]	4	hSpCas9	negative selection	6421633
38339843	38339866	15	-	27260156	EW8	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.47038858628970015	[668]	[741,433,552,1302]	8	hSpCas9	negative selection	6485886
38339874	38339897	15	+	27260156	EW8	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.007738509921946579	[629]	[604,557,454,431]	0	hSpCas9	negative selection	6485887
38322349	38322372	15	-	27260156	EW8	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.010638032366498962	[248]	[241,167,164,235]	0	hSpCas9	negative selection	6485888
38322375	38322398	15	+	27260156	CORL105	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.5045692428602284	[49]	[117,56,89,69]	8	hSpCas9	negative selection	6542882
38299379	38299402	15	+	27260156	CORL105	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.18586727331373504	[446]	[630,493,796,493]	3	hSpCas9	negative selection	6542883
38299469	38299492	15	+	27260156	CORL105	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.5342858086688078	[620]	[1127,921,1321,886]	8	hSpCas9	negative selection	6542884
38339843	38339866	15	-	27260156	CORL105	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.016632540979561905	[668]	[851,693,800,826]	0	hSpCas9	negative selection	6607137
38339874	38339897	15	+	27260156	CORL105	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.15743744796758574	[629]	[984,585,966,784]	3	hSpCas9	negative selection	6607138
38322349	38322372	15	-	27260156	CORL105	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.018288638759360265	[248]	[256,244,375,314]	0	hSpCas9	negative selection	6607139
38322375	38322398	15	+	27260156	HS294T	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.7182400494476111	[49]	[27,41,20,36]	8	hSpCas9	negative selection	6664133
38299379	38299402	15	+	27260156	HS294T	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.028239543020063193	[446]	[216,134,151,169]	0	hSpCas9	negative selection	6664134
38299469	38299492	15	+	27260156	HS294T	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.32554594116283403	[620]	[227,281,375,328]	4	hSpCas9	negative selection	6664135
38339843	38339866	15	-	27260156	HS294T	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.21446499501763233	[668]	[269,152,196,277]	-3	hSpCas9	negative selection	6728388
38339874	38339897	15	+	27260156	HS294T	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.22990736563590064	[629]	[254,312,318,250]	3	hSpCas9	negative selection	6728389
38322349	38322372	15	-	27260156	HS294T	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.23284156980476867	[248]	[60,95,69,105]	-3	hSpCas9	negative selection	6728390
38322375	38322398	15	+	27260156	HCC44	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	-0.004824047998049252	[49]	[110,9,93,28]	0	hSpCas9	negative selection	6785384
38299379	38299402	15	+	27260156	HCC44	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-1.009727186196654	[446]	[340,208,252,214]	-8	hSpCas9	negative selection	6785385
38299469	38299492	15	+	27260156	HCC44	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.35832095222562427	[620]	[886,841,1081,823]	6	hSpCas9	negative selection	6785386
38339843	38339866	15	-	27260156	HCC44	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.08574047310440108	[668]	[878,480,1009,579]	-1	hSpCas9	negative selection	6849639
38339874	38339897	15	+	27260156	HCC44	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.02589832366488859	[629]	[939,442,1067,568]	0	hSpCas9	negative selection	6849640
38322349	38322372	15	-	27260156	HCC44	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.3656163156380966	[248]	[263,196,216,201]	-5	hSpCas9	negative selection	6849641
38322375	38322398	15	+	27260156	G402	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.18114887757524123	[49]	[91,55,83,47]	2	hSpCas9	negative selection	6906635
38299379	38299402	15	+	27260156	G402	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.1865386415543827	[446]	[445,554,649,273]	-2	hSpCas9	negative selection	6906636
38299469	38299492	15	+	27260156	G402	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.7541419356807044	[620]	[1143,965,967,1957]	8	hSpCas9	negative selection	6906637
38339843	38339866	15	-	27260156	G402	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.39005304533276175	[668]	[1146,1095,1176,876]	5	hSpCas9	negative selection	6970890
38339874	38339897	15	+	27260156	G402	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.2686486053222421	[629]	[538,1403,1151,593]	3	hSpCas9	negative selection	6970891
38322349	38322372	15	-	27260156	G402	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.08209064318902859	[248]	[688,453,114,98]	1	hSpCas9	negative selection	6970892
38322375	38322398	15	+	27260156	L33	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	1.1668874823011461	[49]	[89,39,87,121]	9	hSpCas9	negative selection	7027886
38299379	38299402	15	+	27260156	L33	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.1264917993796762	[446]	[395,151,312,373]	-3	hSpCas9	negative selection	7027887
38299469	38299492	15	+	27260156	L33	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.4563337792022016	[620]	[841,310,587,871]	8	hSpCas9	negative selection	7027888
38339843	38339866	15	-	27260156	L33	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.07469899684624187	[668]	[625,259,415,618]	-2	hSpCas9	negative selection	7092141
38339874	38339897	15	+	27260156	L33	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.15830353591776264	[629]	[742,203,340,470]	-4	hSpCas9	negative selection	7092142
38322349	38322372	15	-	27260156	L33	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.14226360030352725	[248]	[231,126,179,271]	3	hSpCas9	negative selection	7092143
38322375	38322398	15	+	27260156	K562	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.057702299722359296	[49]	[51,14,94,23]	0	hSpCas9	negative selection	7149137
38299379	38299402	15	+	27260156	K562	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.4945300247188154	[446]	[434,698,760,358]	6	hSpCas9	negative selection	7149138
38299469	38299492	15	+	27260156	K562	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.5176297743880967	[620]	[637,1086,521,895]	6	hSpCas9	negative selection	7149139
38339843	38339866	15	-	27260156	K562	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.3108932075869012	[668]	[576,902,642,806]	4	hSpCas9	negative selection	7213392
38339874	38339897	15	+	27260156	K562	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.12962512039328755	[629]	[716,847,580,349]	1	hSpCas9	negative selection	7213393
38322349	38322372	15	-	27260156	K562	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.23621842176186647	[248]	[61,226,232,215]	-3	hSpCas9	negative selection	7213394
38322375	38322398	15	+	27260156	HT29	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.5641615697492912	[49]	[121,71,131,39]	9	hSpCas9	negative selection	7270388
38299379	38299402	15	+	27260156	HT29	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.16729641216793387	[446]	[591,707,404,723]	3	hSpCas9	negative selection	7270389
38299469	38299492	15	+	27260156	HT29	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.4750299880793008	[620]	[1086,1167,1180,797]	8	hSpCas9	negative selection	7270390
38339843	38339866	15	-	27260156	HT29	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.2124233230100857	[668]	[1062,1127,704,896]	4	hSpCas9	negative selection	7334643
38339874	38339897	15	+	27260156	HT29	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.14048967345702112	[629]	[1092,883,777,660]	2	hSpCas9	negative selection	7334644
38322349	38322372	15	-	27260156	HT29	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.24336962697775621	[248]	[399,474,247,324]	5	hSpCas9	negative selection	7334645
38322375	38322398	15	+	27260156	MHHES1	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.9759163911743878	[49]	[96,51,151,127]	9	hSpCas9	negative selection	7391639
38299379	38299402	15	+	27260156	MHHES1	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.2652252886353355	[446]	[448,459,1268,276]	5	hSpCas9	negative selection	7391640
38299469	38299492	15	+	27260156	MHHES1	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.6301740784552077	[620]	[1163,1153,1224,837]	9	hSpCas9	negative selection	7391641
38339843	38339866	15	-	27260156	MHHES1	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.2687388400306379	[668]	[675,528,791,513]	-5	hSpCas9	negative selection	7455894
38339874	38339897	15	+	27260156	MHHES1	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.08667767694711737	[629]	[721,1032,532,460]	-2	hSpCas9	negative selection	7455895
38322349	38322372	15	-	27260156	MHHES1	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.14488116944702323	[248]	[147,420,394,88]	-3	hSpCas9	negative selection	7455896
38322375	38322398	15	+	27260156	MEWO	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.8138299405925129	[49]	[73,97,72]	9	hSpCas9	negative selection	7512890
38299379	38299402	15	+	27260156	MEWO	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.19965740875736082	[446]	[579,195,358]	-4	hSpCas9	negative selection	7512891
38299469	38299492	15	+	27260156	MEWO	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.4779502200404367	[620]	[1040,655,775]	8	hSpCas9	negative selection	7512892
38339843	38339866	15	-	27260156	MEWO	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.0736292733699423	[668]	[886,469,663]	1	hSpCas9	negative selection	7577145
38339874	38339897	15	+	27260156	MEWO	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.04337183694776231	[629]	[505,688,606]	1	hSpCas9	negative selection	7577146
38322349	38322372	15	-	27260156	MEWO	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.1551828865289132	[248]	[284,285,211]	3	hSpCas9	negative selection	7577147
38322375	38322398	15	+	27260156	LNCAPCLONEFGC	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	1.1185691555985513	[49]	[130,75,130,60]	9	hSpCas9	negative selection	7634141
38299379	38299402	15	+	27260156	LNCAPCLONEFGC	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.11487726075570275	[446]	[435,327,559,454]	1	hSpCas9	negative selection	7634142
38299469	38299492	15	+	27260156	LNCAPCLONEFGC	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.44296057462558974	[620]	[754,622,832,866]	7	hSpCas9	negative selection	7634143
38339843	38339866	15	-	27260156	LNCAPCLONEFGC	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.030702456155431213	[668]	[491,553,746,606]	0	hSpCas9	negative selection	7698396
38339874	38339897	15	+	27260156	LNCAPCLONEFGC	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.37145936900079113	[629]	[584,600,1063,762]	6	hSpCas9	negative selection	7698397
38322349	38322372	15	-	27260156	LNCAPCLONEFGC	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.04963701866846304	[248]	[309,155,238,171]	-1	hSpCas9	negative selection	7698398
38322375	38322398	15	+	27260156	PANC0327	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	-0.5442229791693971	[49]	[18,52,36,8]	-6	hSpCas9	negative selection	7755392
38299379	38299402	15	+	27260156	PANC0327	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.02297873551916009	[446]	[575,298,322,391]	0	hSpCas9	negative selection	7755393
38299469	38299492	15	+	27260156	PANC0327	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.4262158304003802	[620]	[622,656,833,851]	6	hSpCas9	negative selection	7755394
38339843	38339866	15	-	27260156	PANC0327	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.2060417684348299	[668]	[914,665,558,622]	3	hSpCas9	negative selection	7819647
38339874	38339897	15	+	27260156	PANC0327	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.3132586567872573	[629]	[878,680,606,630]	4	hSpCas9	negative selection	7819648
38322349	38322372	15	-	27260156	PANC0327	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.44548345710722315	[248]	[191,107,124,233]	-6	hSpCas9	negative selection	7819649
38322375	38322398	15	+	27260156	NCIH2009	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.4684032778896219	[49]	[122,151,18]	6	hSpCas9	negative selection	7876643
38299379	38299402	15	+	27260156	NCIH2009	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.21671067623812384	[446]	[742,591,315]	-3	hSpCas9	negative selection	7876644
38299469	38299492	15	+	27260156	NCIH2009	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.5224936995755791	[620]	[1430,931,1415]	7	hSpCas9	negative selection	7876645
38339843	38339866	15	-	27260156	NCIH2009	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.019569820135017568	[668]	[1053,856,880]	0	hSpCas9	negative selection	7940898
38339874	38339897	15	+	27260156	NCIH2009	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.5164397399035824	[629]	[2029,1338,556]	7	hSpCas9	negative selection	7940899
38322349	38322372	15	-	27260156	NCIH2009	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.1222009473282929	[248]	[334,286,339]	-2	hSpCas9	negative selection	7940900
38322375	38322398	15	+	27260156	NCIH1373	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.10384950229667167	[49]	[68,74,56,9]	1	hSpCas9	negative selection	7997894
38299379	38299402	15	+	27260156	NCIH1373	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.6223602028864659	[446]	[568,282,278,53]	-6	hSpCas9	negative selection	7997895
38299469	38299492	15	+	27260156	NCIH1373	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.6203781226306384	[620]	[1453,1072,754,277]	6	hSpCas9	negative selection	7997896
38339843	38339866	15	-	27260156	NCIH1373	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.10981918001041291	[668]	[523,745,799,175]	-1	hSpCas9	negative selection	8062149
38339874	38339897	15	+	27260156	NCIH1373	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.15012813098714906	[629]	[750,633,957,208]	1	hSpCas9	negative selection	8062150
38322349	38322372	15	-	27260156	NCIH1373	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.04433515835825996	[248]	[301,361,119,77]	0	hSpCas9	negative selection	8062151
38322375	38322398	15	+	27260156	PATU8902	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	1.3781047219884917	[49]	[140,298,198,65]	9	hSpCas9	negative selection	8119145
38299379	38299402	15	+	27260156	PATU8902	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.6453520266907503	[446]	[277,234,432,666]	-6	hSpCas9	negative selection	8119146
38299469	38299492	15	+	27260156	PATU8902	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.59136739367047	[620]	[1643,1162,932,1586]	6	hSpCas9	negative selection	8119147
38339843	38339866	15	-	27260156	PATU8902	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.15080544127077555	[668]	[974,1193,836,1194]	1	hSpCas9	negative selection	8183400
38339874	38339897	15	+	27260156	PATU8902	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.47949625813811636	[629]	[1324,1012,1110,1493]	5	hSpCas9	negative selection	8183401
38322349	38322372	15	-	27260156	PATU8902	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.3612784565365099	[248]	[512,372,475,401]	3	hSpCas9	negative selection	8183402
38322375	38322398	15	+	27260156	PANC1	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.6396789126090132	[49]	[62,51,17,120]	9	hSpCas9	negative selection	8240396
38299379	38299402	15	+	27260156	PANC1	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.4844342938015877	[446]	[659,767,397,382]	7	hSpCas9	negative selection	8240397
38299469	38299492	15	+	27260156	PANC1	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.8368705015021751	[620]	[895,1061,1005,868]	9	hSpCas9	negative selection	8240398
38339843	38339866	15	-	27260156	PANC1	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.5712464042155594	[668]	[740,1020,1024,680]	8	hSpCas9	negative selection	8304651
38339874	38339897	15	+	27260156	PANC1	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.48464396203193494	[629]	[740,984,746,613]	7	hSpCas9	negative selection	8304652
38322349	38322372	15	-	27260156	PANC1	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.32995803307364513	[248]	[206,290,309,268]	5	hSpCas9	negative selection	8304653
38322375	38322398	15	+	27260156	PANC0813	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.16251883493947616	[49]	[51,83,67,57]	2	hSpCas9	negative selection	8361647
38299379	38299402	15	+	27260156	PANC0813	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.25949576114429823	[446]	[491,514,482,277]	-4	hSpCas9	negative selection	8361648
38299469	38299492	15	+	27260156	PANC0813	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.18746356427667915	[620]	[848,864,902,712]	3	hSpCas9	negative selection	8361649
38339843	38339866	15	-	27260156	PANC0813	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.48961913205773766	[668]	[764,567,451,475]	-6	hSpCas9	negative selection	8425902
38339874	38339897	15	+	27260156	PANC0813	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.0942736350547746	[629]	[806,766,628,584]	-1	hSpCas9	negative selection	8425903
38322349	38322372	15	-	27260156	PANC0813	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.45856431014311394	[248]	[303,223,186,147]	-6	hSpCas9	negative selection	8425904
38322375	38322398	15	+	27260156	RDES	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.6303709828744801	[49]	[115,69,34,131]	8	hSpCas9	negative selection	8482898
38299379	38299402	15	+	27260156	RDES	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.3129169770637695	[446]	[368,332,482,488]	-5	hSpCas9	negative selection	8482899
38299469	38299492	15	+	27260156	RDES	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.3874172776724801	[620]	[742,819,1066,1172]	6	hSpCas9	negative selection	8482900
38339843	38339866	15	-	27260156	RDES	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.11257035607851884	[668]	[761,721,746,1138]	1	hSpCas9	negative selection	8547153
38339874	38339897	15	+	27260156	RDES	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.11898211199729714	[629]	[745,732,887,768]	2	hSpCas9	negative selection	8547154
38322349	38322372	15	-	27260156	RDES	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.003011596898253366	[248]	[172,326,328,335]	0	hSpCas9	negative selection	8547155
38322375	38322398	15	+	27260156	PC3	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	-0.023928643422144624	[49]	[38,33,63,64]	0	hSpCas9	negative selection	8604149
38299379	38299402	15	+	27260156	PC3	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.19983742772237906	[446]	[229,310,764,432]	-4	hSpCas9	negative selection	8604150
38299469	38299492	15	+	27260156	PC3	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.470970569479999	[620]	[594,697,1502,923]	8	hSpCas9	negative selection	8604151
38339843	38339866	15	-	27260156	PC3	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.05675544492132978	[668]	[350,611,1493,730]	1	hSpCas9	negative selection	8668404
38339874	38339897	15	+	27260156	PC3	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.2725890676954533	[629]	[451,771,1252,814]	6	hSpCas9	negative selection	8668405
38322349	38322372	15	-	27260156	PC3	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.2946860812734019	[248]	[182,151,326,178]	-6	hSpCas9	negative selection	8668406
38322375	38322398	15	+	27260156	PATU8988T	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	1.1437213707493044	[49]	[114,160,77,75]	9	hSpCas9	negative selection	8725400
38299379	38299402	15	+	27260156	PATU8988T	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.38510136151463203	[446]	[235,325,448,307]	-6	hSpCas9	negative selection	8725401
38299469	38299492	15	+	27260156	PATU8988T	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.377595393425526	[620]	[563,754,922,879]	6	hSpCas9	negative selection	8725402
38339843	38339866	15	-	27260156	PATU8988T	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.5567005597868825	[668]	[410,408,389,554]	-7	hSpCas9	negative selection	8789655
38339874	38339897	15	+	27260156	PATU8988T	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.4710695275379788	[629]	[711,1484,579,645]	7	hSpCas9	negative selection	8789656
38322349	38322372	15	-	27260156	PATU8988T	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.10853349889260011	[248]	[96,260,344,339]	1	hSpCas9	negative selection	8789657
38322375	38322398	15	+	27260156	T47D	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.4190018857874418	[49]	[68,87,87,64]	8	hSpCas9	negative selection	8846651
38299379	38299402	15	+	27260156	T47D	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.19885601738965503	[446]	[446,459,413,494]	-4	hSpCas9	negative selection	8846652
38299469	38299492	15	+	27260156	T47D	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.25157846886780605	[620]	[798,942,851,842]	5	hSpCas9	negative selection	8846653
38339843	38339866	15	-	27260156	T47D	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.009445662184339843	[668]	[881,709,785,765]	0	hSpCas9	negative selection	8910906
38339874	38339897	15	+	27260156	T47D	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.027786131465467545	[629]	[675,824,675,692]	0	hSpCas9	negative selection	8910907
38322349	38322372	15	-	27260156	T47D	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.045640528143899406	[248]	[347,254,290,307]	1	hSpCas9	negative selection	8910908
38322375	38322398	15	+	27260156	SU8686	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.0975800411147314	[49]	[59,13,71,73]	1	hSpCas9	negative selection	8967902
38299379	38299402	15	+	27260156	SU8686	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.08226514031789615	[446]	[364,426,398,741]	1	hSpCas9	negative selection	8967903
38299469	38299492	15	+	27260156	SU8686	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.338759444372495	[620]	[717,707,823,894]	6	hSpCas9	negative selection	8967904
38339843	38339866	15	-	27260156	SU8686	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.15294053540997066	[668]	[532,560,684,1301]	2	hSpCas9	negative selection	9032157
38339874	38339897	15	+	27260156	SU8686	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.036459992283835896	[629]	[580,576,612,831]	0	hSpCas9	negative selection	9032158
38322349	38322372	15	-	27260156	SU8686	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.05832445406466935	[248]	[219,243,217,366]	1	hSpCas9	negative selection	9032159
38322375	38322398	15	+	27260156	SKES1	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.6440978406175861	[49]	[73,95,56,84]	9	hSpCas9	negative selection	9089153
38299379	38299402	15	+	27260156	SKES1	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.23264516260406554	[446]	[418,496,297,326]	-5	hSpCas9	negative selection	9089154
38299469	38299492	15	+	27260156	SKES1	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.4447440908696178	[620]	[856,845,828,834]	8	hSpCas9	negative selection	9089155
38339843	38339866	15	-	27260156	SKES1	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.300682623851909	[668]	[906,871,856,677]	6	hSpCas9	negative selection	9153408
38339874	38339897	15	+	27260156	SKES1	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	0.08088900743868332	[629]	[855,722,556,562]	1	hSpCas9	negative selection	9153409
38322349	38322372	15	-	27260156	SKES1	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.2818400587070172	[248]	[268,218,157,182]	-6	hSpCas9	negative selection	9153410
38322375	38322398	15	+	27260156	TOV112D	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	-0.28659846011195045	[49]	[39,101,29,7]	-5	hSpCas9	negative selection	9210404
38299379	38299402	15	+	27260156	TOV112D	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.08237665650635298	[446]	[413,618,496,397]	1	hSpCas9	negative selection	9210405
38299469	38299492	15	+	27260156	TOV112D	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.463113809537632	[620]	[950,1182,809,579]	8	hSpCas9	negative selection	9210406
38339843	38339866	15	-	27260156	TOV112D	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.13231383805903685	[668]	[916,1055,508,553]	2	hSpCas9	negative selection	9274659
38339874	38339897	15	+	27260156	TOV112D	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.19672474738565185	[629]	[628,651,551,403]	-4	hSpCas9	negative selection	9274660
38322349	38322372	15	-	27260156	TOV112D	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.344089147006179	[248]	[215,226,165,185]	-6	hSpCas9	negative selection	9274661
38322375	38322398	15	+	27260156	TC71	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	0.5741658764397979	[49]	[53,78,104,80]	9	hSpCas9	negative selection	9331655
38299379	38299402	15	+	27260156	TC71	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	-0.25383206146964193	[446]	[387,305,539,366]	-6	hSpCas9	negative selection	9331656
38299469	38299492	15	+	27260156	TC71	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.2726941212751764	[620]	[755,903,648,920]	6	hSpCas9	negative selection	9331657
38339843	38339866	15	-	27260156	TC71	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	-0.011207135291171122	[668]	[843,660,678,656]	0	hSpCas9	negative selection	9395910
38339874	38339897	15	+	27260156	TC71	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.09878487111666323	[629]	[595,537,616,781]	-3	hSpCas9	negative selection	9395911
38322349	38322372	15	-	27260156	TC71	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.15797767546632324	[248]	[225,206,260,263]	-4	hSpCas9	negative selection	9395912
38322375	38322398	15	+	27260156	TC32	viability	AGGTATCCGAAGAGCTATAGAGG	SPRED1	ENSG00000166068	-0.05543376685431456	[49]	[39,18,72,62]	-1	hSpCas9	negative selection	9452906
38299379	38299402	15	+	27260156	TC32	viability	TTATGCACGAGTGCGAGCTGTGG	SPRED1	ENSG00000166068	0.3092037334774884	[446]	[576,487,353,608]	5	hSpCas9	negative selection	9452907
38299469	38299492	15	+	27260156	TC32	viability	TGTCTTCAAAGTCCCTCATCAGG	SPRED1	ENSG00000166068	0.4703039217546486	[620]	[781,644,882,960]	7	hSpCas9	negative selection	9452908
38339843	38339866	15	-	27260156	TC32	viability	TCTGGCATTCAGATCTTCAAAGG	SPRED1	ENSG00000166068	0.29432125931715103	[668]	[665,614,946,920]	5	hSpCas9	negative selection	9517161
38339874	38339897	15	+	27260156	TC32	viability	CATGCAAAGCCAAGCCAATCAGG	SPRED1	ENSG00000166068	-0.036423015362699485	[629]	[422,588,708,589]	0	hSpCas9	negative selection	9517162
38322349	38322372	15	-	27260156	TC32	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.20778246581994908	[248]	[205,248,305,328]	4	hSpCas9	negative selection	9517163
38253173	38253196	15	+	27869803	HPAFII	viability after 27 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.049384403255717135	[322]	[118,222,NaN]	0	hSpCas9	negative selection	9553316
38299437	38299460	15	-	27869803	HPAFII	viability after 27 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.5725849553733007	[448]	[305,35,NaN]	-4	hSpCas9	negative selection	9553317
38349437	38349460	15	-	27869803	HPAFII	viability after 27 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	-0.2413073085138493	[473]	[206,213,NaN]	-2	hSpCas9	negative selection	9553318
38351529	38351552	15	+	27869803	HPAFII	viability after 27 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	-0.08657240017578405	[297]	[152,142,NaN]	0	hSpCas9	negative selection	9553319
38351607	38351630	15	-	27869803	HPAFII	viability after 27 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-1.6345179379937158	[312]	[46,57,NaN]	-8	hSpCas9	negative selection	9553320
38253173	38253196	15	+	27869803	HPAFII	viability after 15 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.3717449991595976	[322]	[279,260,NaN]	-4	hSpCas9	negative selection	9635765
38299437	38299460	15	-	27869803	HPAFII	viability after 15 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.37769806966682595	[448]	[593,232,NaN]	-4	hSpCas9	negative selection	9635766
38349437	38349460	15	-	27869803	HPAFII	viability after 15 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	-0.1848563269536112	[473]	[523,400,NaN]	-2	hSpCas9	negative selection	9635767
38351529	38351552	15	+	27869803	HPAFII	viability after 15 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.3431408031305571	[297]	[581,296,NaN]	4	hSpCas9	negative selection	9635768
38351607	38351630	15	-	27869803	HPAFII	viability after 15 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-1.054772630840725	[312]	[119,187,NaN]	-8	hSpCas9	negative selection	9635769
38253173	38253196	15	+	27869803	ASPC1	viability after 36 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.06891109787851141	[825]	[596,209,165]	0	hSpCas9	negative selection	9718214
38299437	38299460	15	-	27869803	ASPC1	viability after 36 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	1.0635530086954643	[1196]	[209,1761,623]	8	hSpCas9	negative selection	9718215
38349437	38349460	15	-	27869803	ASPC1	viability after 36 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.7660227844810517	[846]	[895,354,338]	7	hSpCas9	negative selection	9718216
38351529	38351552	15	+	27869803	ASPC1	viability after 36 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.26901874972670775	[805]	[575,332,173]	2	hSpCas9	negative selection	9718217
38351607	38351630	15	-	27869803	ASPC1	viability after 36 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	0.4174771938692342	[826]	[355,303,466]	4	hSpCas9	negative selection	9718218
38253173	38253196	15	+	27869803	PATU8988S	viability after 35 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.8304957447466624	[302]	[221,211,NaN]	8	hSpCas9	negative selection	9800663
38299437	38299460	15	-	27869803	PATU8988S	viability after 35 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.0864878953260233	[1133]	[273,586,NaN]	-1	hSpCas9	negative selection	9800664
38349437	38349460	15	-	27869803	PATU8988S	viability after 35 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.1645556433166706	[808]	[229,500,NaN]	2	hSpCas9	negative selection	9800665
38351529	38351552	15	+	27869803	PATU8988S	viability after 35 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.15312832337550203	[679]	[320,287,NaN]	1	hSpCas9	negative selection	9800666
38351607	38351630	15	-	27869803	PATU8988S	viability after 35 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-0.22743883484130595	[650]	[201,245,NaN]	-2	hSpCas9	negative selection	9800667
38253173	38253196	15	+	27869803	PATU8988S	viability after 31 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	1.051130481301561	[302]	[230,274,NaN]	9	hSpCas9	negative selection	9883112
38299437	38299460	15	-	27869803	PATU8988S	viability after 31 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.2732223627726815	[1133]	[184,614,NaN]	-3	hSpCas9	negative selection	9883113
38349437	38349460	15	-	27869803	PATU8988S	viability after 31 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	0.014727730082758628	[808]	[196,489,NaN]	0	hSpCas9	negative selection	9883114
38351529	38351552	15	+	27869803	PATU8988S	viability after 31 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.2759840639879965	[679]	[271,399,NaN]	3	hSpCas9	negative selection	9883115
38351607	38351630	15	-	27869803	PATU8988S	viability after 31 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-0.01288257484049296	[650]	[229,291,NaN]	0	hSpCas9	negative selection	9883116
38253173	38253196	15	+	27869803	HPAFII	viability after 35 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.6098341624220911	[322]	[154,355,NaN]	4	hSpCas9	negative selection	9965561
38299437	38299460	15	-	27869803	HPAFII	viability after 35 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.3451452343560145	[448]	[296,45,NaN]	-2	hSpCas9	negative selection	9965562
38349437	38349460	15	-	27869803	HPAFII	viability after 35 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	-0.5513297173556573	[473]	[127,203,NaN]	-3	hSpCas9	negative selection	9965563
38351529	38351552	15	+	27869803	HPAFII	viability after 35 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	0.5429831745322631	[297]	[176,267,NaN]	3	hSpCas9	negative selection	9965564
38351607	38351630	15	-	27869803	HPAFII	viability after 35 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-2.7776897548242006	[312]	[0,47,NaN]	-8	hSpCas9	negative selection	9965565
38253173	38253196	15	+	27869803	HPAFII	viability after 31 days	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.454045797115817	[322]	[221,276,NaN]	3	hSpCas9	negative selection	10048010
38299437	38299460	15	-	27869803	HPAFII	viability after 31 days	CTTAGTCCACTCCCTCCAAGTGG	SPRED1	ENSG00000166068	-0.7126908122362743	[448]	[192,110,NaN]	-5	hSpCas9	negative selection	10048011
38349437	38349460	15	-	27869803	HPAFII	viability after 31 days	CTGCTCTGAATGTCCAAGCCTGG	SPRED1	ENSG00000166068	-0.25933244039323144	[473]	[171,276,NaN]	-2	hSpCas9	negative selection	10048012
38351529	38351552	15	+	27869803	HPAFII	viability after 31 days	CTGCTTGCGATGGTTAGCCCTGG	SPRED1	ENSG00000166068	-0.1665596411463348	[297]	[137,160,NaN]	-1	hSpCas9	negative selection	10048013
38351607	38351630	15	-	27869803	HPAFII	viability after 31 days	CACATGCCTCACCACAGCGATGG	SPRED1	ENSG00000166068	-1.8181600154256226	[312]	[0,102,NaN]	-8	hSpCas9	negative selection	10048014
38349459	38349482	15	+	28162770	P31FUJ	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	0.012775004342868906	[193]	[229]	0	hSpCas9	negative selection	10242363
38339804	38339827	15	-	28162770	P31FUJ	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	0.2781597148630004	[119]	[170]	3	hSpCas9	negative selection	10242364
38253173	38253196	15	+	28162770	P31FUJ	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	1.457513296453006	[21]	[70]	9	hSpCas9	negative selection	10242365
38299407	38299430	15	+	28162770	P31FUJ	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	-0.4611850635932096	[361]	[308]	-4	hSpCas9	negative selection	10242366
38299526	38299549	15	+	28162770	P31FUJ	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	0.3453711306441385	[70]	[105]	4	hSpCas9	negative selection	10242367
38299426	38299449	15	+	28162770	P31FUJ	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	0.4172909514666656	[396]	[622]	4	hSpCas9	negative selection	10242368
38349445	38349468	15	+	28162770	P31FUJ	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.6657123874684132	[713]	[1330]	7	hSpCas9	negative selection	10242369
38322287	38322310	15	+	28162770	P31FUJ	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	0.15396756984165982	[334]	[437]	1	hSpCas9	negative selection	10242370
38322342	38322365	15	+	28162770	P31FUJ	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	0.7898240998618391	[600]	[1220]	8	hSpCas9	negative selection	10242371
38322349	38322372	15	-	28162770	P31FUJ	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.561522769194107	[142]	[247]	6	hSpCas9	negative selection	10242372
38349459	38349482	15	+	28162770	TF1	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	NaN	[NaN]	[217]	1	hSpCas9	negative selection	10411729
38339804	38339827	15	-	28162770	TF1	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10411730
38253173	38253196	15	+	28162770	TF1	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10411731
38299407	38299430	15	+	28162770	TF1	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10411732
38299526	38299549	15	+	28162770	TF1	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	NaN	[NaN]	[78]	1	hSpCas9	negative selection	10411733
38299426	38299449	15	+	28162770	TF1	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	NaN	[NaN]	[416]	1	hSpCas9	negative selection	10411734
38349445	38349468	15	+	28162770	TF1	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	NaN	[NaN]	[1002]	1	hSpCas9	negative selection	10411735
38322287	38322310	15	+	28162770	TF1	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	NaN	[NaN]	[308]	1	hSpCas9	negative selection	10411736
38322342	38322365	15	+	28162770	TF1	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	NaN	[NaN]	[781]	1	hSpCas9	negative selection	10411737
38322349	38322372	15	-	28162770	TF1	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	NaN	[NaN]	[84]	1	hSpCas9	negative selection	10411738
38349459	38349482	15	+	28162770	SKM1	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	1.8768287672574293	[68]	[447]	9	hSpCas9	negative selection	10581095
38339804	38339827	15	-	28162770	SKM1	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	2.259792393141642	[14]	[126]	9	hSpCas9	negative selection	10581096
38253173	38253196	15	+	28162770	SKM1	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	3.570315724756755	[3]	[83]	9	hSpCas9	negative selection	10581097
38299407	38299430	15	+	28162770	SKM1	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	2.4546024063558662	[96]	[939]	9	hSpCas9	negative selection	10581098
38299526	38299549	15	+	28162770	SKM1	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	1.4581062211707299	[20]	[101]	9	hSpCas9	negative selection	10581099
38299426	38299449	15	+	28162770	SKM1	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	2.417606858890977	[118]	[1123]	9	hSpCas9	negative selection	10581100
38349445	38349468	15	+	28162770	SKM1	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	2.1892841095245097	[190]	[1539]	9	hSpCas9	negative selection	10581101
38322287	38322310	15	+	28162770	SKM1	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	2.5604679388004077	[55]	[583]	9	hSpCas9	negative selection	10581102
38322342	38322365	15	+	28162770	SKM1	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	1.7011089221824638	[138]	[798]	9	hSpCas9	negative selection	10581103
38322349	38322372	15	-	28162770	SKM1	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	2.047937761413621	[28]	[211]	9	hSpCas9	negative selection	10581104
38349459	38349482	15	+	28162770	SKM1	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	1.8768287672574293	[68]	[447]	9	hSpCas9	negative selection	10750461
38339804	38339827	15	-	28162770	SKM1	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	2.259792393141642	[14]	[126]	9	hSpCas9	negative selection	10750462
38253173	38253196	15	+	28162770	SKM1	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	3.570315724756755	[3]	[83]	9	hSpCas9	negative selection	10750463
38299407	38299430	15	+	28162770	SKM1	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	2.4546024063558662	[96]	[939]	9	hSpCas9	negative selection	10750464
38299526	38299549	15	+	28162770	SKM1	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	1.4581062211707299	[20]	[101]	9	hSpCas9	negative selection	10750465
38299426	38299449	15	+	28162770	SKM1	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	2.417606858890977	[118]	[1123]	9	hSpCas9	negative selection	10750466
38349445	38349468	15	+	28162770	SKM1	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	2.1892841095245097	[190]	[1539]	9	hSpCas9	negative selection	10750467
38322287	38322310	15	+	28162770	SKM1	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	2.5604679388004077	[55]	[583]	9	hSpCas9	negative selection	10750468
38322342	38322365	15	+	28162770	SKM1	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	1.7011089221824638	[138]	[798]	9	hSpCas9	negative selection	10750469
38322349	38322372	15	-	28162770	SKM1	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	2.047937761413621	[28]	[211]	9	hSpCas9	negative selection	10750470
38349459	38349482	15	+	28162770	PL21	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	-0.7237779926798509	[276]	[72]	-5	hSpCas9	negative selection	10919827
38339804	38339827	15	-	28162770	PL21	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	-0.5606727216312539	[60]	[17]	-4	hSpCas9	negative selection	10919828
38253173	38253196	15	+	28162770	PL21	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.9518634789557301	[39]	[8]	-6	hSpCas9	negative selection	10919829
38299407	38299430	15	+	28162770	PL21	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	1.0192434952260045	[296]	[261]	8	hSpCas9	negative selection	10919830
38299526	38299549	15	+	28162770	PL21	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	2.224252070606128	[88]	[180]	9	hSpCas9	negative selection	10919831
38299426	38299449	15	+	28162770	PL21	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	-0.1557358123213799	[429]	[167]	-1	hSpCas9	negative selection	10919832
38349445	38349468	15	+	28162770	PL21	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.9079588629960096	[539]	[440]	7	hSpCas9	negative selection	10919833
38322287	38322310	15	+	28162770	PL21	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	0.05654876086047045	[284]	[128]	0	hSpCas9	negative selection	10919834
38322342	38322365	15	+	28162770	PL21	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	0.7174451651072138	[421]	[301]	6	hSpCas9	negative selection	10919835
38322349	38322372	15	-	28162770	PL21	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.9647615515583916	[92]	[78]	7	hSpCas9	negative selection	10919836
38349459	38349482	15	+	28162770	P31FUJ	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	0.012775004342868906	[193]	[229]	0	hSpCas9	negative selection	11089193
38339804	38339827	15	-	28162770	P31FUJ	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	0.2781597148630004	[119]	[170]	3	hSpCas9	negative selection	11089194
38253173	38253196	15	+	28162770	P31FUJ	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	1.457513296453006	[21]	[70]	9	hSpCas9	negative selection	11089195
38299407	38299430	15	+	28162770	P31FUJ	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	-0.4611850635932096	[361]	[308]	-4	hSpCas9	negative selection	11089196
38299526	38299549	15	+	28162770	P31FUJ	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	0.3453711306441385	[70]	[105]	4	hSpCas9	negative selection	11089197
38299426	38299449	15	+	28162770	P31FUJ	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	0.4172909514666656	[396]	[622]	4	hSpCas9	negative selection	11089198
38349445	38349468	15	+	28162770	P31FUJ	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.6657123874684132	[713]	[1330]	7	hSpCas9	negative selection	11089199
38322287	38322310	15	+	28162770	P31FUJ	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	0.15396756984165982	[334]	[437]	1	hSpCas9	negative selection	11089200
38322342	38322365	15	+	28162770	P31FUJ	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	0.7898240998618391	[600]	[1220]	8	hSpCas9	negative selection	11089201
38322349	38322372	15	-	28162770	P31FUJ	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.561522769194107	[142]	[247]	6	hSpCas9	negative selection	11089202
38349459	38349482	15	+	28162770	OCIAML5	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	0.23071110492046132	[126]	[268]	2	hSpCas9	negative selection	11258559
38339804	38339827	15	-	28162770	OCIAML5	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	-0.23315673821950322	[83]	[128]	-2	hSpCas9	negative selection	11258560
38253173	38253196	15	+	28162770	OCIAML5	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.004069664309046761	[29]	[53]	0	hSpCas9	negative selection	11258561
38299407	38299430	15	+	28162770	OCIAML5	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.31785843057831564	[207]	[467]	2	hSpCas9	negative selection	11258562
38299526	38299549	15	+	28162770	OCIAML5	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	-0.36967380378338865	[67]	[94]	-3	hSpCas9	negative selection	11258563
38299426	38299449	15	+	28162770	OCIAML5	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	0.07036487564029947	[276]	[524]	0	hSpCas9	negative selection	11258564
38349445	38349468	15	+	28162770	OCIAML5	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.7738091231232123	[393]	[1215]	6	hSpCas9	negative selection	11258565
38322287	38322310	15	+	28162770	OCIAML5	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	0.2691470161050835	[250]	[545]	2	hSpCas9	negative selection	11258566
38322342	38322365	15	+	28162770	OCIAML5	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	0.49955056375231655	[403]	[1030]	4	hSpCas9	negative selection	11258567
38322349	38322372	15	-	28162770	OCIAML5	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.810063790379619	[90]	[287]	7	hSpCas9	negative selection	11258568
38349459	38349482	15	+	28162770	EOL1	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	-0.544664867859348	[406]	[146]	-4	hSpCas9	negative selection	11427925
38339804	38339827	15	-	28162770	EOL1	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	1.6227208827396815	[97]	[158]	9	hSpCas9	negative selection	11427926
38253173	38253196	15	+	28162770	EOL1	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	2.865654082516966	[49]	[191]	9	hSpCas9	negative selection	11427927
38299407	38299430	15	+	28162770	EOL1	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.39667148838124855	[606]	[420]	3	hSpCas9	negative selection	11427928
38299526	38299549	15	+	28162770	EOL1	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	1.6743211420373612	[156]	[263]	9	hSpCas9	negative selection	11427929
38299426	38299449	15	+	28162770	EOL1	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	0.10198947191680818	[786]	[444]	0	hSpCas9	negative selection	11427930
38349445	38349468	15	+	28162770	EOL1	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.118595567213021	[770]	[440]	1	hSpCas9	negative selection	11427931
38322287	38322310	15	+	28162770	EOL1	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	0.6409659883326552	[296]	[243]	6	hSpCas9	negative selection	11427932
38322342	38322365	15	+	28162770	EOL1	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	1.2531230642997038	[562]	[706]	9	hSpCas9	negative selection	11427933
38322349	38322372	15	-	28162770	EOL1	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.05908989494936212	[132]	[72]	0	hSpCas9	negative selection	11427934
38349459	38349482	15	+	28162770	MOLM13	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	0.6916643569311455	[297]	[347]	5	hSpCas9	negative selection	11597291
38339804	38339827	15	-	28162770	MOLM13	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	0.7158168949881644	[111]	[132]	5	hSpCas9	negative selection	11597292
38253173	38253196	15	+	28162770	MOLM13	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-1.172568231768281	[52]	[16]	-6	hSpCas9	negative selection	11597293
38299407	38299430	15	+	28162770	MOLM13	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.7051263844316554	[441]	[520]	5	hSpCas9	negative selection	11597294
38299526	38299549	15	+	28162770	MOLM13	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	0.5445106631474913	[164]	[173]	4	hSpCas9	negative selection	11597295
38299426	38299449	15	+	28162770	MOLM13	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	0.3627284513520228	[568]	[528]	2	hSpCas9	negative selection	11597296
38349445	38349468	15	+	28162770	MOLM13	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.12552676176381428	[870]	[686]	0	hSpCas9	negative selection	11597297
38322287	38322310	15	+	28162770	MOLM13	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	-0.09470530614812278	[479]	[324]	0	hSpCas9	negative selection	11597298
38322342	38322365	15	+	28162770	MOLM13	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	-0.057767290414195704	[559]	[388]	0	hSpCas9	negative selection	11597299
38322349	38322372	15	-	28162770	MOLM13	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.8481614626627461	[188]	[245]	6	hSpCas9	negative selection	11597300
38349459	38349482	15	+	28162770	HEL	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	0.15518883293714528	[271]	[193]	1	hSpCas9	negative selection	11766657
38339804	38339827	15	-	28162770	HEL	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	-0.34358623110256636	[104]	[52]	-2	hSpCas9	negative selection	11766658
38253173	38253196	15	+	28162770	HEL	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-0.30835156751869697	[57]	[29]	-2	hSpCas9	negative selection	11766659
38299407	38299430	15	+	28162770	HEL	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	1.1721090067581956	[387]	[559]	8	hSpCas9	negative selection	11766660
38299526	38299549	15	+	28162770	HEL	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	0.29760334595166954	[140]	[110]	2	hSpCas9	negative selection	11766661
38299426	38299449	15	+	28162770	HEL	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	1.1228256344154004	[579]	[808]	8	hSpCas9	negative selection	11766662
38349445	38349468	15	+	28162770	HEL	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	-0.11498532233264669	[699]	[413]	-1	hSpCas9	negative selection	11766663
38322287	38322310	15	+	28162770	HEL	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	0.09411817834292124	[391]	[267]	0	hSpCas9	negative selection	11766664
38322342	38322365	15	+	28162770	HEL	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	0.36245594524438607	[588]	[484]	3	hSpCas9	negative selection	11766665
38322349	38322372	15	-	28162770	HEL	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-0.32119191329212127	[157]	[80]	-2	hSpCas9	negative selection	11766666
38349459	38349482	15	+	28162770	MV411	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	0.5450103753210479	[226]	[278]	5	hSpCas9	negative selection	11936023
38339804	38339827	15	-	28162770	MV411	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	1.1392887469271527	[89]	[166]	8	hSpCas9	negative selection	11936024
38253173	38253196	15	+	28162770	MV411	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.20013183600441842	[30]	[29]	1	hSpCas9	negative selection	11936025
38299407	38299430	15	+	28162770	MV411	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.5008568677398478	[275]	[328]	4	hSpCas9	negative selection	11936026
38299526	38299549	15	+	28162770	MV411	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	0.6259491740365053	[99]	[129]	5	hSpCas9	negative selection	11936027
38299426	38299449	15	+	28162770	MV411	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	0.032658313556202634	[440]	[379]	0	hSpCas9	negative selection	11936028
38349445	38349468	15	+	28162770	MV411	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.5671613747434074	[523]	[653]	5	hSpCas9	negative selection	11936029
38322287	38322310	15	+	28162770	MV411	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	0.6530763520593696	[230]	[305]	6	hSpCas9	negative selection	11936030
38322342	38322365	15	+	28162770	MV411	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	0.7794155955722104	[378]	[547]	7	hSpCas9	negative selection	11936031
38322349	38322372	15	-	28162770	MV411	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	1.931935725054846	[55]	[179]	9	hSpCas9	negative selection	11936032
38349459	38349482	15	+	28162770	MONOMAC1	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	-0.5903792752390784	[175]	[133]	-5	hSpCas9	negative selection	12105389
38339804	38339827	15	-	28162770	MONOMAC1	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	1.3223373120340258	[44]	[128]	9	hSpCas9	negative selection	12105390
38253173	38253196	15	+	28162770	MONOMAC1	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-1.004391769117158	[20]	[11]	-7	hSpCas9	negative selection	12105391
38299407	38299430	15	+	28162770	MONOMAC1	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.730648948124556	[224]	[427]	7	hSpCas9	negative selection	12105392
38299526	38299549	15	+	28162770	MONOMAC1	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	-0.8626178079889943	[45]	[28]	-6	hSpCas9	negative selection	12105393
38299426	38299449	15	+	28162770	MONOMAC1	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	-0.19703684705955382	[312]	[312]	-2	hSpCas9	negative selection	12105394
38349445	38349468	15	+	28162770	MONOMAC1	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.13856618472488513	[419]	[529]	1	hSpCas9	negative selection	12105395
38322287	38322310	15	+	28162770	MONOMAC1	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	0.713695814843359	[124]	[234]	6	hSpCas9	negative selection	12105396
38322342	38322365	15	+	28162770	MONOMAC1	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	0.8162111343791314	[270]	[546]	7	hSpCas9	negative selection	12105397
38322349	38322372	15	-	28162770	MONOMAC1	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	-1.1145746868675808	[67]	[35]	-7	hSpCas9	negative selection	12105398
38349459	38349482	15	+	28162770	OCIAML2	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	0.5649940844885601	[34]	[286]	5	hSpCas9	negative selection	12274755
38339804	38339827	15	-	28162770	OCIAML2	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	0.16163839025735194	[14]	[92]	1	hSpCas9	negative selection	12274756
38253173	38253196	15	+	28162770	OCIAML2	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	-3.0555923259633175	[8]	[5]	-9	hSpCas9	negative selection	12274757
38299407	38299430	15	+	28162770	OCIAML2	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.2982509490008072	[75]	[517]	3	hSpCas9	negative selection	12274758
38299526	38299549	15	+	28162770	OCIAML2	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	0.6992951762001514	[15]	[143]	6	hSpCas9	negative selection	12274759
38299426	38299449	15	+	28162770	OCIAML2	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	0.9520989104326936	[75]	[814]	8	hSpCas9	negative selection	12274760
38349445	38349468	15	+	28162770	OCIAML2	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	0.8607057229008996	[106]	[1076]	8	hSpCas9	negative selection	12274761
38322287	38322310	15	+	28162770	OCIAML2	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	1.0292160618410442	[31]	[361]	8	hSpCas9	negative selection	12274762
38322342	38322365	15	+	28162770	OCIAML2	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	0.5555800540806874	[74]	[610]	5	hSpCas9	negative selection	12274763
38322349	38322372	15	-	28162770	OCIAML2	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.5091922928202085	[26]	[212]	5	hSpCas9	negative selection	12274764
38349459	38349482	15	+	28162770	OCIAML3	viability	GAAGTATGGAATACGTACAGCGG	SPRED1	ENSG00000166068	-0.43835676986396865	[78]	[175]	-3	hSpCas9	negative selection	12444121
38339804	38339827	15	-	28162770	OCIAML3	viability	TGAGCTTCTATAAGGCTCACTGG	SPRED1	ENSG00000166068	1.6039317372877457	[16]	[155]	9	hSpCas9	negative selection	12444122
38253173	38253196	15	+	28162770	OCIAML3	viability	CGGTGAGGGAAAGATGAGCGAGG	SPRED1	ENSG00000166068	0.7036729083165221	[11]	[58]	6	hSpCas9	negative selection	12444123
38299407	38299430	15	+	28162770	OCIAML3	viability	ACCCGAGATGACTCAAGTGGTGG	SPRED1	ENSG00000166068	0.9680284635474856	[73]	[436]	8	hSpCas9	negative selection	12444124
38299526	38299549	15	+	28162770	OCIAML3	viability	AGAGCGACTCAGGGACAAAATGG	SPRED1	ENSG00000166068	1.6679131451989222	[26]	[258]	9	hSpCas9	negative selection	12444125
38299426	38299449	15	+	28162770	OCIAML3	viability	GTGGATGGTTACCACTTGGAGGG	SPRED1	ENSG00000166068	0.299555423637363	[115]	[430]	3	hSpCas9	negative selection	12444126
38349445	38349468	15	+	28162770	OCIAML3	viability	GGACATTCAGAGCAGAAGTATGG	SPRED1	ENSG00000166068	-0.03172057757090396	[170]	[504]	0	hSpCas9	negative selection	12444127
38322287	38322310	15	+	28162770	OCIAML3	viability	TCACTCCAACATTTCACCACTGG	SPRED1	ENSG00000166068	0.7691431172897122	[68]	[354]	7	hSpCas9	negative selection	12444128
38322342	38322365	15	+	28162770	OCIAML3	viability	TCAAAGTCCTGCTGATGCTAGGG	SPRED1	ENSG00000166068	0.6076262208454875	[139]	[643]	5	hSpCas9	negative selection	12444129
38322349	38322372	15	-	28162770	OCIAML3	viability	TCAAAAGCCCTAGCATCAGCAGG	SPRED1	ENSG00000166068	0.5835305452280243	[20]	[94]	5	hSpCas9	negative selection	12444130