Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:399473
• Symbol:SPRED3
• Description:sprouty related EVH1 domain containing 3

DataSource: http://genomecrispr.dkfz.de/#!/results/SPRED3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
38394768	38394791	19	-	26472758	Jiyoye	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-0.5928246184941265	[71]	[35]	-4	hSpCas9	negative selection	155624
38390308	38390331	19	+	26472758	Jiyoye	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	-0.1339328296258553	[242]	[166]	-1	hSpCas9	negative selection	155625
38392041	38392064	19	+	26472758	Jiyoye	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	-0.461340693355889	[523]	[286]	-3	hSpCas9	negative selection	155626
38392242	38392265	19	-	26472758	Jiyoye	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	-0.8249980606231598	[147]	[62]	-5	hSpCas9	negative selection	155627
38390377	38390400	19	-	26472758	Jiyoye	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.9678903359803523	[159]	[235]	6	hSpCas9	negative selection	155628
38390431	38390454	19	-	26472758	Jiyoye	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	-0.10537862368723283	[203]	[142]	0	hSpCas9	negative selection	155629
38390464	38390487	19	-	26472758	Jiyoye	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-3.680287459744466	[16]	[0]	-9	hSpCas9	negative selection	155630
38392077	38392100	19	+	26472758	Jiyoye	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.3305540999029608	[57]	[54]	2	hSpCas9	negative selection	155631
38394662	38394685	19	-	26472758	Jiyoye	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	0.258031942200064	[111]	[100]	2	hSpCas9	negative selection	155632
38394687	38394710	19	+	26472758	Jiyoye	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	-0.17778711921528279	[224]	[149]	-1	hSpCas9	negative selection	155633
38394768	38394791	19	-	26472758	KBM7	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-0.4331099917047667	[207,182]	[77,58]	-4	hSpCas9	negative selection	346742
38390308	38390331	19	+	26472758	KBM7	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.21040862746689326	[1239,819]	[515,582]	2	hSpCas9	negative selection	346743
38392041	38392064	19	+	26472758	KBM7	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	0.7139950633342758	[1185,1006]	[1092,618]	7	hSpCas9	negative selection	346744
38392242	38392265	19	-	26472758	KBM7	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	-0.6998138728651638	[600,408]	[76,203]	-5	hSpCas9	negative selection	346745
38390377	38390400	19	-	26472758	KBM7	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.7586681903972261	[557,495]	[479,363]	8	hSpCas9	negative selection	346746
38390431	38390454	19	-	26472758	KBM7	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.418428820413503	[744,476]	[278,464]	4	hSpCas9	negative selection	346747
38390464	38390487	19	-	26472758	KBM7	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	0.13695229278445842	[9,42]	[11,16]	1	hSpCas9	negative selection	346748
38392077	38392100	19	+	26472758	KBM7	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	1.1428742206919582	[320,301]	[210,424]	9	hSpCas9	negative selection	346749
38394662	38394685	19	-	26472758	KBM7	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	0.5285701505809637	[416,373]	[417,133]	6	hSpCas9	negative selection	346750
38394687	38394710	19	+	26472758	KBM7	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	0.1268563498842793	[940,435]	[361,323]	1	hSpCas9	negative selection	346751
38394768	38394791	19	-	26472758	Raji	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-0.9906485475869274	[136]	[15]	-6	hSpCas9	negative selection	537860
38390308	38390331	19	+	26472758	Raji	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	-0.598169106161145	[423]	[64]	-5	hSpCas9	negative selection	537861
38392041	38392064	19	+	26472758	Raji	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	0.6021482271231776	[439]	[154]	5	hSpCas9	negative selection	537862
38392242	38392265	19	-	26472758	Raji	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	-1.2528726781728623	[266]	[25]	-7	hSpCas9	negative selection	537863
38390377	38390400	19	-	26472758	Raji	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.6660118882812932	[257]	[94]	6	hSpCas9	negative selection	537864
38390431	38390454	19	-	26472758	Raji	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	1.0216536613477154	[207]	[97]	8	hSpCas9	negative selection	537865
38390464	38390487	19	-	26472758	Raji	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.47757896534755684	[29]	[4]	-4	hSpCas9	negative selection	537866
38392077	38392100	19	+	26472758	Raji	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.3265008246771864	[188]	[54]	3	hSpCas9	negative selection	537867
38394662	38394685	19	-	26472758	Raji	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	-0.8059048314330699	[225]	[29]	-6	hSpCas9	negative selection	537868
38394687	38394710	19	+	26472758	Raji	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	0.23778017262927426	[295]	[80]	2	hSpCas9	negative selection	537869
38394768	38394791	19	-	26472758	K562	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-0.5962733782652697	[196]	[109]	-4	hSpCas9	negative selection	728978
38390308	38390331	19	+	26472758	K562	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.37069925644988966	[961]	[1049]	3	hSpCas9	negative selection	728979
38392041	38392064	19	+	26472758	K562	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	0.11084570155042339	[1062]	[968]	0	hSpCas9	negative selection	728980
38392242	38392265	19	-	26472758	K562	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	0.025200554125142577	[453]	[389]	0	hSpCas9	negative selection	728981
38390377	38390400	19	-	26472758	K562	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	-0.3405437730547092	[545]	[363]	-2	hSpCas9	negative selection	728982
38390431	38390454	19	-	26472758	K562	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.9513413139143796	[426]	[696]	7	hSpCas9	negative selection	728983
38390464	38390487	19	-	26472758	K562	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	1.5663468225538093	[25]	[64]	9	hSpCas9	negative selection	728984
38392077	38392100	19	+	26472758	K562	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.07730874183118852	[255]	[227]	0	hSpCas9	negative selection	728985
38394662	38394685	19	-	26472758	K562	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	0.18195464071979325	[353]	[338]	1	hSpCas9	negative selection	728986
38394687	38394710	19	+	26472758	K562	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	0.4400538482146544	[481]	[551]	3	hSpCas9	negative selection	728987
38388489	38388512	19	+	26627737	DLD1	viability	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	0.3064190271850235	[357]	[155,210,62]	3	hSpCas9	negative selection	804523
38390464	38390487	19	-	26627737	DLD1	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	1.3862245580293666	[71]	[62,75,40]	9	hSpCas9	negative selection	804524
38392077	38392100	19	+	26627737	DLD1	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-1.8262313732007227	[188]	[6,0,37]	-8	hSpCas9	negative selection	804525
38392275	38392298	19	-	26627737	DLD1	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-2.05353301349368	[367]	[6,42,32]	-9	hSpCas9	negative selection	804526
38394630	38394653	19	+	26627737	DLD1	viability	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	0.29649718367151134	[863]	[334,409,263]	3	hSpCas9	negative selection	804527
38395824	38395847	19	-	26627737	DLD1	viability	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	-0.12845731577234654	[1045]	[391,416,120]	-1	hSpCas9	negative selection	804528
38388489	38388512	19	+	26627737	GBM cells	viability after 5 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	-0.22342166803836655	[245]	[119,105]	-3	hSpCas9	negative selection	886838
38390464	38390487	19	-	26627737	GBM cells	viability after 5 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	0.36548167480461125	[54]	[43,31]	5	hSpCas9	negative selection	886839
38392077	38392100	19	+	26627737	GBM cells	viability after 5 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.028974415450058633	[52]	[36,20]	0	hSpCas9	negative selection	886840
38392275	38392298	19	-	26627737	GBM cells	viability after 5 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.13178292233723088	[94]	[46,45]	-2	hSpCas9	negative selection	886841
38394630	38394653	19	+	26627737	GBM cells	viability after 5 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.5283141652599381	[514]	[167,214]	-7	hSpCas9	negative selection	886842
38395824	38395847	19	-	26627737	GBM cells	viability after 5 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	0.18431609374793384	[319]	[221,167]	3	hSpCas9	negative selection	886843
38388489	38388512	19	+	26627737	GBM cells	viability after 13 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	-0.4571123145651581	[245]	[142,59]	-5	hSpCas9	negative selection	969153
38390464	38390487	19	-	26627737	GBM cells	viability after 13 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.08472124552805571	[54]	[31,24]	-1	hSpCas9	negative selection	969154
38392077	38392100	19	+	26627737	GBM cells	viability after 13 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.557570704505207	[52]	[70,18]	7	hSpCas9	negative selection	969155
38392275	38392298	19	-	26627737	GBM cells	viability after 13 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-1.251163407285017	[94]	[19,22]	-8	hSpCas9	negative selection	969156
38394630	38394653	19	+	26627737	GBM cells	viability after 13 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.7870649522207707	[514]	[167,156]	-7	hSpCas9	negative selection	969157
38395824	38395847	19	-	26627737	GBM cells	viability after 13 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	-0.12994742307120521	[319]	[188,133]	-1	hSpCas9	negative selection	969158
38388489	38388512	19	+	26627737	GBM cells	viability after 21 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	-0.6470558677567709	[245]	[88,81]	-5	hSpCas9	negative selection	1051468
38390464	38390487	19	-	26627737	GBM cells	viability after 21 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	0.2585207104140623	[54]	[29,40]	2	hSpCas9	negative selection	1051469
38392077	38392100	19	+	26627737	GBM cells	viability after 21 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-0.07920873271961337	[52]	[32,21]	0	hSpCas9	negative selection	1051470
38392275	38392298	19	-	26627737	GBM cells	viability after 21 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.8037226100227441	[94]	[27,30]	-6	hSpCas9	negative selection	1051471
38394630	38394653	19	+	26627737	GBM cells	viability after 21 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.6389271427097517	[514]	[198,161]	-5	hSpCas9	negative selection	1051472
38395824	38395847	19	-	26627737	GBM cells	viability after 21 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	0.08751882856189808	[319]	[202,167]	0	hSpCas9	negative selection	1051473
38388489	38388512	19	+	26627737	RPE1	viability after 9 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	-0.18204587592052907	[893]	[223,275]	-1	hSpCas9	negative selection	1133783
38390464	38390487	19	-	26627737	RPE1	viability after 9 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	0.9459295793093037	[38]	[2,49]	6	hSpCas9	negative selection	1133784
38392077	38392100	19	+	26627737	RPE1	viability after 9 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.13941085001291187	[117]	[41,38]	1	hSpCas9	negative selection	1133785
38392275	38392298	19	-	26627737	RPE1	viability after 9 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-2.002439143271832	[850]	[62,70]	-8	hSpCas9	negative selection	1133786
38394630	38394653	19	+	26627737	RPE1	viability after 9 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.18345771988107318	[1397]	[215,603]	-1	hSpCas9	negative selection	1133787
38395824	38395847	19	-	26627737	RPE1	viability after 9 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	0.6646980977527385	[536]	[300,221]	4	hSpCas9	negative selection	1133788
38388489	38388512	19	+	26627737	RPE1	viability after 12 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	0.10910694313263686	[893]	[277,238]	0	hSpCas9	negative selection	1216098
38390464	38390487	19	-	26627737	RPE1	viability after 12 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	0.5285500879799487	[38]	[18,10]	3	hSpCas9	negative selection	1216099
38392077	38392100	19	+	26627737	RPE1	viability after 12 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.4813067741558985	[117]	[69,16]	3	hSpCas9	negative selection	1216100
38392275	38392298	19	-	26627737	RPE1	viability after 12 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-1.6675515202235502	[850]	[19,126]	-8	hSpCas9	negative selection	1216101
38394630	38394653	19	+	26627737	RPE1	viability after 12 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.5197715684473414	[1397]	[192,334]	-4	hSpCas9	negative selection	1216102
38395824	38395847	19	-	26627737	RPE1	viability after 12 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	1.2599346853149944	[536]	[464,218]	7	hSpCas9	negative selection	1216103
38388489	38388512	19	+	26627737	RPE1	viability after 15 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	0.12140407924571545	[893]	[325,225]	0	hSpCas9	negative selection	1298413
38390464	38390487	19	-	26627737	RPE1	viability after 15 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	1.6626423380731707	[38]	[38,30]	8	hSpCas9	negative selection	1298414
38392077	38392100	19	+	26627737	RPE1	viability after 15 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.39913077856220713	[117]	[42,44]	2	hSpCas9	negative selection	1298415
38392275	38392298	19	-	26627737	RPE1	viability after 15 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-1.9910011744321534	[850]	[0,117]	-8	hSpCas9	negative selection	1298416
38394630	38394653	19	+	26627737	RPE1	viability after 15 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	0.17488995881000624	[1397]	[365,523]	1	hSpCas9	negative selection	1298417
38395824	38395847	19	-	26627737	RPE1	viability after 15 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	0.9430745811232331	[536]	[316,267]	5	hSpCas9	negative selection	1298418
38388489	38388512	19	+	26627737	RPE1	viability after 18 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	0.4626346647374486	[893]	[287,379]	3	hSpCas9	negative selection	1380728
38390464	38390487	19	-	26627737	RPE1	viability after 18 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	0.6816386536329277	[38]	[27,4]	4	hSpCas9	negative selection	1380729
38392077	38392100	19	+	26627737	RPE1	viability after 18 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	1.1475945426453031	[117]	[71,68]	6	hSpCas9	negative selection	1380730
38392275	38392298	19	-	26627737	RPE1	viability after 18 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.9855429070520662	[850]	[100,131]	-6	hSpCas9	negative selection	1380731
38394630	38394653	19	+	26627737	RPE1	viability after 18 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.5346164457958529	[1397]	[258,261]	-3	hSpCas9	negative selection	1380732
38395824	38395847	19	-	26627737	RPE1	viability after 18 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	1.0285635979587777	[536]	[386,197]	6	hSpCas9	negative selection	1380733
38388489	38388512	19	+	26627737	HeLa	viability after 8 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	-0.5681209174078293	[289]	[55,93,97]	-5	hSpCas9	negative selection	1463043
38390464	38390487	19	-	26627737	HeLa	viability after 8 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-1.155915279360828	[166]	[35,50,12]	-8	hSpCas9	negative selection	1463044
38392077	38392100	19	+	26627737	HeLa	viability after 8 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	1.1941682013895534	[102]	[86,51,160]	8	hSpCas9	negative selection	1463045
38392275	38392298	19	-	26627737	HeLa	viability after 8 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-1.0285441299459872	[299]	[67,62,61]	-8	hSpCas9	negative selection	1463046
38394630	38394653	19	+	26627737	HeLa	viability after 8 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.19697928213651228	[696]	[464,228,151]	-2	hSpCas9	negative selection	1463047
38395824	38395847	19	-	26627737	HeLa	viability after 8 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	1.0175565661019013	[329]	[126,268,429]	7	hSpCas9	negative selection	1463048
38388489	38388512	19	+	26627737	HeLa	viability after 12 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	-0.49328489146815346	[289]	[148,49,61]	-4	hSpCas9	negative selection	1545358
38390464	38390487	19	-	26627737	HeLa	viability after 12 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.7119003398501582	[166]	[70,34,21]	-6	hSpCas9	negative selection	1545359
38392077	38392100	19	+	26627737	HeLa	viability after 12 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-0.17771788821820778	[102]	[5,27,78]	-1	hSpCas9	negative selection	1545360
38392275	38392298	19	-	26627737	HeLa	viability after 12 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.6463072097147926	[299]	[7,93,131]	-5	hSpCas9	negative selection	1545361
38394630	38394653	19	+	26627737	HeLa	viability after 12 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.4452638809471907	[696]	[279,179,179]	-4	hSpCas9	negative selection	1545362
38395824	38395847	19	-	26627737	HeLa	viability after 12 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	0.8799700639485215	[329]	[93,112,555]	6	hSpCas9	negative selection	1545363
38388489	38388512	19	+	26627737	HeLa	viability after 15 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	0.10746527556556551	[289]	[151,92,136]	0	hSpCas9	negative selection	1627673
38390464	38390487	19	-	26627737	HeLa	viability after 15 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.48096050845321603	[166]	[60,35,48]	-4	hSpCas9	negative selection	1627674
38392077	38392100	19	+	26627737	HeLa	viability after 15 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.9611295166225965	[102]	[72,5,172]	7	hSpCas9	negative selection	1627675
38392275	38392298	19	-	26627737	HeLa	viability after 15 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.149437168342585	[299]	[8,154,252]	1	hSpCas9	negative selection	1627676
38394630	38394653	19	+	26627737	HeLa	viability after 15 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.290323536761389	[696]	[196,273,224]	-3	hSpCas9	negative selection	1627677
38395824	38395847	19	-	26627737	HeLa	viability after 15 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	1.0356054642572285	[329]	[272,328,219]	7	hSpCas9	negative selection	1627678
38388489	38388512	19	+	26627737	HeLa	viability after 18 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	0.09226959039020971	[289]	[96,79,136]	0	hSpCas9	negative selection	1709988
38390464	38390487	19	-	26627737	HeLa	viability after 18 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.45345485617707326	[166]	[40,31,48]	-4	hSpCas9	negative selection	1709989
38392077	38392100	19	+	26627737	HeLa	viability after 18 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.9723953747563987	[102]	[50,3,172]	7	hSpCas9	negative selection	1709990
38392275	38392298	19	-	26627737	HeLa	viability after 18 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.14442474235450162	[299]	[6,125,252]	1	hSpCas9	negative selection	1709991
38394630	38394653	19	+	26627737	HeLa	viability after 18 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.3008587875786243	[696]	[123,232,224]	-3	hSpCas9	negative selection	1709992
38395824	38395847	19	-	26627737	HeLa	viability after 18 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	1.0239498636603033	[329]	[183,265,219]	7	hSpCas9	negative selection	1709993
38388489	38388512	19	+	26627737	HCT116	viability after 6 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	-1.041959031221822	[572]	[84,20]	-5	hSpCas9	negative selection	1792303
38390464	38390487	19	-	26627737	HCT116	viability after 6 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	0.6331934753232265	[104]	[13,31]	3	hSpCas9	negative selection	1792304
38392077	38392100	19	+	26627737	HCT116	viability after 6 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	2.2846853388712427	[125]	[62,114]	9	hSpCas9	negative selection	1792305
38392275	38392298	19	-	26627737	HCT116	viability after 6 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	2.0798566195007395	[238]	[163,155]	8	hSpCas9	negative selection	1792306
38394630	38394653	19	+	26627737	HCT116	viability after 6 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	1.0522090517400886	[1234]	[332,440]	6	hSpCas9	negative selection	1792307
38395824	38395847	19	-	26627737	HCT116	viability after 6 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	-0.33934851752602463	[751]	[115,80]	-2	hSpCas9	negative selection	1792308
38388489	38388512	19	+	26627737	HCT116	viability after 8 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	0.10811904225143382	[227]	[130,126,147]	1	hSpCas9	negative selection	1874618
38390464	38390487	19	-	26627737	HCT116	viability after 8 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	1.2071659236580823	[12]	[27,19,1]	8	hSpCas9	negative selection	1874619
38392077	38392100	19	+	26627737	HCT116	viability after 8 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-0.4143059815458132	[123]	[89,53,10]	-5	hSpCas9	negative selection	1874620
38392275	38392298	19	-	26627737	HCT116	viability after 8 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.3392003845906163	[139]	[34,104,150]	3	hSpCas9	negative selection	1874621
38394630	38394653	19	+	26627737	HCT116	viability after 8 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	0.7675408381228233	[351]	[230,360,395]	7	hSpCas9	negative selection	1874622
38395824	38395847	19	-	26627737	HCT116	viability after 8 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	-0.6945687950883421	[493]	[158,224,120]	-7	hSpCas9	negative selection	1874623
38388489	38388512	19	+	26627737	HCT116	viability after 9 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	0.6302993811965321	[572]	[371,129]	4	hSpCas9	negative selection	1956933
38390464	38390487	19	-	26627737	HCT116	viability after 9 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	2.908389844089402	[104]	[14,364]	9	hSpCas9	negative selection	1956934
38392077	38392100	19	+	26627737	HCT116	viability after 9 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.3384763477320887	[125]	[65,23]	2	hSpCas9	negative selection	1956935
38392275	38392298	19	-	26627737	HCT116	viability after 9 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.3138144257411848	[238]	[80,77]	2	hSpCas9	negative selection	1956936
38394630	38394653	19	+	26627737	HCT116	viability after 9 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.2584302028748974	[1234]	[168,359]	-2	hSpCas9	negative selection	1956937
38395824	38395847	19	-	26627737	HCT116	viability after 9 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	-0.11407845336184039	[751]	[251,132]	-1	hSpCas9	negative selection	1956938
38388489	38388512	19	+	26627737	HCT116	viability after 12 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	-0.219802424612987	[227]	[90,114,103]	-2	hSpCas9	negative selection	2039248
38390464	38390487	19	-	26627737	HCT116	viability after 12 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	0.7121246204145892	[12]	[0,32,0]	6	hSpCas9	negative selection	2039249
38392077	38392100	19	+	26627737	HCT116	viability after 12 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-0.8486215021894365	[123]	[12,93,4]	-7	hSpCas9	negative selection	2039250
38392275	38392298	19	-	26627737	HCT116	viability after 12 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.25948965556721126	[139]	[37,42,104]	-3	hSpCas9	negative selection	2039251
38394630	38394653	19	+	26627737	HCT116	viability after 12 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	1.005337487050635	[351]	[327,336,451]	8	hSpCas9	negative selection	2039252
38395824	38395847	19	-	26627737	HCT116	viability after 12 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	-0.9802309753474208	[493]	[94,213,90]	-8	hSpCas9	negative selection	2039253
38388489	38388512	19	+	26627737	HCT116	viability after 15 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	0.035367105844431646	[227]	[121,137,140]	0	hSpCas9	negative selection	2121563
38390464	38390487	19	-	26627737	HCT116	viability after 15 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.09817466101519123	[12]	[6,12,0]	-1	hSpCas9	negative selection	2121564
38392077	38392100	19	+	26627737	HCT116	viability after 15 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-0.8406125393506969	[123]	[12,59,42]	-7	hSpCas9	negative selection	2121565
38392275	38392298	19	-	26627737	HCT116	viability after 15 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.17029307394143867	[139]	[111,67,93]	1	hSpCas9	negative selection	2121566
38394630	38394653	19	+	26627737	HCT116	viability after 15 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	0.6935460051810631	[351]	[258,342,369]	6	hSpCas9	negative selection	2121567
38395824	38395847	19	-	26627737	HCT116	viability after 15 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	-0.70172929369308	[493]	[212,141,172]	-6	hSpCas9	negative selection	2121568
38388489	38388512	19	+	26627737	HCT116	viability after 18 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	-0.17891286091957098	[227]	[52,107,131]	-2	hSpCas9	negative selection	2203878
38390464	38390487	19	-	26627737	HCT116	viability after 18 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	0.519255199029673	[12]	[5,18,0]	4	hSpCas9	negative selection	2203879
38392077	38392100	19	+	26627737	HCT116	viability after 18 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-0.7498608483589495	[123]	[24,30,51]	-6	hSpCas9	negative selection	2203880
38392275	38392298	19	-	26627737	HCT116	viability after 18 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.13348925454072924	[139]	[61,76,83]	1	hSpCas9	negative selection	2203881
38394630	38394653	19	+	26627737	HCT116	viability after 18 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	0.5962606014531102	[351]	[272,154,354]	5	hSpCas9	negative selection	2203882
38395824	38395847	19	-	26627737	HCT116	viability after 18 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	-1.1662027255226557	[493]	[71,156,85]	-8	hSpCas9	negative selection	2203883
38390040	38390063	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGGTGGGTACAGAGAGAAAGGG	SPRED3	ENSG00000188766	4.464843848568765	[225,398]	[1934,1092]	9	dCas9-VP64	positive selection	2392584
38390064	38390087	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGACATGGAGAAGAAGATAGAGG	SPRED3	ENSG00000188766	2.345292022547327	[85,84]	[152,34]	7	dCas9-VP64	positive selection	2392585
38390088	38390111	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAGAGAAGAGATGGCATGAGG	SPRED3	ENSG00000188766	1.2079609829326274	[240,138]	[77,115]	5	dCas9-VP64	positive selection	2392586
38397821	38397844	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACTTTGGGAGGCCAAGGGAG	SPRED3	ENSG00000188766	0.21234444010885142	[57,122]	[21,23]	1	dCas9-VP64	positive selection	2422474
38390040	38390063	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGGTGGGTACAGAGAGAAAGGG	SPRED3	ENSG00000188766	0.7216366993566097	[179,296]	[95,157]	5	dCas9-VP64	positive selection	2487839
38390064	38390087	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGACATGGAGAAGAAGATAGAGG	SPRED3	ENSG00000188766	-0.522218935809901	[194,110]	[47,21]	-5	dCas9-VP64	positive selection	2487840
38390088	38390111	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAGAGAAGAGATGGCATGAGG	SPRED3	ENSG00000188766	-0.43603361172935684	[422,160]	[64,75]	-4	dCas9-VP64	positive selection	2487841
38397821	38397844	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACTTTGGGAGGCCAAGGGAG	SPRED3	ENSG00000188766	-0.9329704115466368	[100,219]	[26,25]	-8	dCas9-VP64	positive selection	2517729
38395485	38395508	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCGTGAACGGTAGAAGCGGAGGG	SPRED3	ENSG00000188766	-0.1797571894851418	[1,2]	[3,0]	-3	hSpCas9	positive selection	3023502
38392053	38392076	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAACTCATCAGCCTCTGCAGGG	SPRED3	ENSG00000188766	0.48977363924086803	[2,3]	[3,3]	8	hSpCas9	positive selection	3023503
38390438	38390461	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGGCACTACGTCATCCACGGGG	SPRED3	ENSG00000188766	0.1873377179339109	[2,2]	[2,2]	4	hSpCas9	positive selection	3023504
38390452	38390475	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCCCGGAGGCGTTCCCCGTGG	SPRED3	ENSG00000188766	-0.0863950171964234	[3,2]	[2,2]	-1	hSpCas9	positive selection	3023505
38395485	38395508	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCGTGAACGGTAGAAGCGGAGGG	SPRED3	ENSG00000188766	-0.20160956291795396	[1,1]	[1,0]	-3	hSpCas9	positive selection	3091360
38392053	38392076	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAACTCATCAGCCTCTGCAGGG	SPRED3	ENSG00000188766	-0.14782833440830567	[2,2]	[3,0]	-2	hSpCas9	positive selection	3091361
38390438	38390461	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGGCACTACGTCATCCACGGGG	SPRED3	ENSG00000188766	-0.21853508218935097	[2,2]	[2,0]	-3	hSpCas9	positive selection	3091362
38390452	38390475	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCCCGGAGGCGTTCCCCGTGG	SPRED3	ENSG00000188766	-0.590935857602	[3,3]	[1,0]	-7	hSpCas9	positive selection	3091363
38392267	38392290		+	24336571	A375	resistance to PLX after 7 days	AGAGACCCCCTGCCCTCTGACGG	SPRED3	ENSG00000188766	-0.2421915731274168	[6,5]	[4,5]	-7	hSpCas9	positive selection	3147261
38394718	38394741		+	24336571	A375	resistance to PLX after 7 days	ATCACGATGGAGTCAGCTTCAGG	SPRED3	ENSG00000188766	0.2240280671452836	[12,12]	[15,13]	6	hSpCas9	positive selection	3147262
38394776	38394799		-	24336571	A375	resistance to PLX after 7 days	CCCAGGTCGCACCTGAGCGGAGG	SPRED3	ENSG00000188766	0.2331003490094825	[1,2]	[2,2]	6	hSpCas9	positive selection	3147263
38392275	38392298		-	24336571	A375	resistance to PLX after 7 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.10270229233382966	[6,7]	[7,6]	3	hSpCas9	positive selection	3147264
38392267	38392290		+	24336571	A375	resistance to PLX after 14 days	AGAGACCCCCTGCCCTCTGACGG	SPRED3	ENSG00000188766	-0.819733418130573	[10,10]	[1,1]	-8	hSpCas9	positive selection	3205054
38394718	38394741		+	24336571	A375	resistance to PLX after 14 days	ATCACGATGGAGTCAGCTTCAGG	SPRED3	ENSG00000188766	0.5315599683461605	[11,15]	[7,10]	5	hSpCas9	positive selection	3205055
38394776	38394799		-	24336571	A375	resistance to PLX after 14 days	CCCAGGTCGCACCTGAGCGGAGG	SPRED3	ENSG00000188766	0.40387850247484747	[4,2]	[1,2]	4	hSpCas9	positive selection	3205056
38392275	38392298		-	24336571	A375	resistance to PLX after 14 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.1698135210507269	[3,6]	[2,2]	1	hSpCas9	positive selection	3205057
38392267	38392290		+	24336571	A375	viability after 7 days	AGAGACCCCCTGCCCTCTGACGG	SPRED3	ENSG00000188766	-0.5562210561799695	[9]	[6,5]	-7	hSpCas9	negative selection	3262847
38394718	38394741		+	24336571	A375	viability after 7 days	ATCACGATGGAGTCAGCTTCAGG	SPRED3	ENSG00000188766	0.18774600680518866	[11]	[12,12]	3	hSpCas9	negative selection	3262848
38394776	38394799		-	24336571	A375	viability after 7 days	CCCAGGTCGCACCTGAGCGGAGG	SPRED3	ENSG00000188766	-0.18015289030368953	[2]	[1,2]	-3	hSpCas9	negative selection	3262849
38392275	38392298		-	24336571	A375	viability after 7 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.5742598601747629	[4]	[6,7]	8	hSpCas9	negative selection	3262850
38392267	38392290		+	24336571	A375	viability after 14 days	AGAGACCCCCTGCCCTCTGACGG	SPRED3	ENSG00000188766	0.15284535376613506	[9]	[10,10]	2	hSpCas9	negative selection	3320640
38394718	38394741		+	24336571	A375	viability after 14 days	ATCACGATGGAGTCAGCTTCAGG	SPRED3	ENSG00000188766	0.3494692223244703	[11]	[11,15]	4	hSpCas9	negative selection	3320641
38394776	38394799		-	24336571	A375	viability after 14 days	CCCAGGTCGCACCTGAGCGGAGG	SPRED3	ENSG00000188766	0.4525014398350993	[2]	[4,2]	6	hSpCas9	negative selection	3320642
38392275	38392298		-	24336571	A375	viability after 14 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.28823491937600076	[4]	[3,6]	4	hSpCas9	negative selection	3320643
38394645	38394668	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	4.087401210003523	[8,8]	[0,0]	9	hSpCas9	positive selection	3394795
38392017	38392040	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.976293465313867	[300,300]	[0,0]	-6	hSpCas9	positive selection	3394796
38392275	38392298	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-1.3901322150090851	[400,400]	[0,0]	-8	hSpCas9	positive selection	3394797
38395485	38395508	19	-	26780180	HT29	viability (Avana library 4 designs)	CCGTGAACGGTAGAAGCGGAGGG	SPRED3	ENSG00000188766	2.55623794527215	[]	[]	8	hSpCas9	negative selection	3462132
38392053	38392076	19	-	26780180	HT29	viability (Avana library 4 designs)	GGAACTCATCAGCCTCTGCAGGG	SPRED3	ENSG00000188766	0.677605120523056	[]	[]	2	hSpCas9	negative selection	3462133
38390437	38390460	19	+	26780180	HT29	viability (Avana library 4 designs)	GGGGCACTACGTCATCCACGGGG	SPRED3	ENSG00000188766	0.23819142078272	[]	[]	0	hSpCas9	negative selection	3462134
38390452	38390475	19	-	26780180	HT29	viability (Avana library 4 designs)	GGTCCCGGAGGCGTTCCCCGTGG	SPRED3	ENSG00000188766	2.1414590806101	[]	[]	7	hSpCas9	negative selection	3462135
38390437	38390460	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGGCACTACGTCATCCACGGGG	SPRED3	ENSG00000188766	3.27861951634886	[]	[]	5	hSpCas9	negative selection	3563512
38390452	38390475	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCCCGGAGGCGTTCCCCGTGG	SPRED3	ENSG00000188766	5.70145105304719	[]	[]	8	hSpCas9	negative selection	3563513
38395485	38395508	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCGTGAACGGTAGAAGCGGAGGG	SPRED3	ENSG00000188766	2.91093419005232	[]	[]	4	hSpCas9	negative selection	3563514
38392053	38392076	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAACTCATCAGCCTCTGCAGGG	SPRED3	ENSG00000188766	-2.62597830975587	[]	[]	-3	hSpCas9	negative selection	3563515
38392068	38392091	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGTTCCAGAAGAGCCTGCTGG	SPRED3	ENSG00000188766	-1.80548001413084	[]	[]	-2	hSpCas9	negative selection	3563516
38394678	38394701	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGCTGGGAGGAGTCTCCTGGCGG	SPRED3	ENSG00000188766	2.56350112558914	[]	[]	4	hSpCas9	negative selection	3563517
38390437	38390460	19	+	26780180	A375	viability (Avana lentiGuide)	GGGGCACTACGTCATCCACGGGG	SPRED3	ENSG00000188766	8.53051173997345	[]	[]	6	hSpCas9	negative selection	3672171
38390452	38390475	19	-	26780180	A375	viability (Avana lentiGuide)	GGTCCCGGAGGCGTTCCCCGTGG	SPRED3	ENSG00000188766	9.66108176014191	[]	[]	6	hSpCas9	negative selection	3672172
38395485	38395508	19	-	26780180	A375	viability (Avana lentiGuide)	CCGTGAACGGTAGAAGCGGAGGG	SPRED3	ENSG00000188766	-1.16631104464481	[]	[]	-2	hSpCas9	negative selection	3672173
38392053	38392076	19	-	26780180	A375	viability (Avana lentiGuide)	GGAACTCATCAGCCTCTGCAGGG	SPRED3	ENSG00000188766	-2.75553133736315	[]	[]	-5	hSpCas9	negative selection	3672174
38392068	38392091	19	+	26780180	A375	viability (Avana lentiGuide)	TGAGTTCCAGAAGAGCCTGCTGG	SPRED3	ENSG00000188766	7.02581577465484	[]	[]	5	hSpCas9	negative selection	3672175
38394678	38394701	19	-	26780180	A375	viability (Avana lentiGuide)	CGCTGGGAGGAGTCTCCTGGCGG	SPRED3	ENSG00000188766	4.03998031278267	[]	[]	4	hSpCas9	negative selection	3672176
38390437	38390460	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGGCACTACGTCATCCACGGGG	SPRED3	ENSG00000188766	0.03934911765286926	[4]	[3,4]	1	hSpCas9	positive selection	3780778
38390452	38390475	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCCCGGAGGCGTTCCCCGTGG	SPRED3	ENSG00000188766	0.24175516607188013	[4]	[5,4]	7	hSpCas9	positive selection	3780779
38395485	38395508	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGTGAACGGTAGAAGCGGAGGG	SPRED3	ENSG00000188766	0.3813705764963717	[4]	[6,4]	9	hSpCas9	positive selection	3780780
38392053	38392076	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAACTCATCAGCCTCTGCAGGG	SPRED3	ENSG00000188766	-0.25262020632253185	[4]	[3,3]	-4	hSpCas9	positive selection	3780781
38392068	38392091	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGTTCCAGAAGAGCCTGCTGG	SPRED3	ENSG00000188766	-0.13988699062346713	[5]	[5,3]	-2	hSpCas9	positive selection	3780782
38394678	38394701	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGCTGGGAGGAGTCTCCTGGCGG	SPRED3	ENSG00000188766	0.21309806590590707	[5]	[6,6]	6	hSpCas9	positive selection	3780783
38390437	38390460	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGGCACTACGTCATCCACGGGG	SPRED3	ENSG00000188766	-0.11045983969643082	[5]	[3,4]	-1	hSpCas9	positive selection	3889385
38390452	38390475	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCCCGGAGGCGTTCCCCGTGG	SPRED3	ENSG00000188766	-0.9309732854519049	[5]	[1,2]	-8	hSpCas9	positive selection	3889386
38395485	38395508	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGTGAACGGTAGAAGCGGAGGG	SPRED3	ENSG00000188766	-0.9306363840430432	[4]	[1,1]	-8	hSpCas9	positive selection	3889387
38392053	38392076	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAACTCATCAGCCTCTGCAGGG	SPRED3	ENSG00000188766	0.11599426328760243	[5]	[4,5]	2	hSpCas9	positive selection	3889388
38392068	38392091	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGTTCCAGAAGAGCCTGCTGG	SPRED3	ENSG00000188766	-0.09403199689831084	[6]	[5,4]	-1	hSpCas9	positive selection	3889389
38394678	38394701	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGCTGGGAGGAGTCTCCTGGCGG	SPRED3	ENSG00000188766	-0.17135053448736262	[6]	[4,3]	-2	hSpCas9	positive selection	3889390
38394645	38394668	19	-	26780180	A375	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.225628255813848	[]	[]	0	hSpCas9	negative selection	3999150
38392100	38392123	19	-	26780180	A375	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	1.03562935470827	[]	[]	5	hSpCas9	negative selection	3999151
38392275	38392298	19	-	26780180	A375	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	1.14855736546953	[]	[]	6	hSpCas9	negative selection	3999152
38395562	38395585	19	+	26780180	A375	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	1.17839791540888	[]	[]	6	hSpCas9	negative selection	3999153
38395498	38395521	19	-	26780180	A375	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	1.63723059690172	[]	[]	8	hSpCas9	negative selection	3999154
38392017	38392040	19	-	26780180	A375	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	2.3374884519633	[]	[]	9	hSpCas9	negative selection	3999155
38394645	38394668	19	-	26780180	HT29	viability (GeCKOv2 library)	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.0764085594210579	[]	[]	0	hSpCas9	negative selection	4107116
38392100	38392123	19	-	26780180	HT29	viability (GeCKOv2 library)	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	-0.213784224650738	[]	[]	-6	hSpCas9	negative selection	4107117
38392275	38392298	19	-	26780180	HT29	viability (GeCKOv2 library)	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.785024103337199	[]	[]	3	hSpCas9	negative selection	4107118
38395562	38395585	19	+	26780180	HT29	viability (GeCKOv2 library)	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	1.03605180232701	[]	[]	5	hSpCas9	negative selection	4107119
38395498	38395521	19	-	26780180	HT29	viability (GeCKOv2 library)	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	1.92974946716525	[]	[]	9	hSpCas9	negative selection	4107120
38392017	38392040	19	-	26780180	HT29	viability (GeCKOv2 library)	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	1.35090880752703	[]	[]	7	hSpCas9	negative selection	4107121
38392267	38392290	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGAGACCCCCTGCCCTCTGACGG	SPRED3	ENSG00000188766	0.05832280829696429	[3]	[3,0]	1	hSpCas9	positive selection	4173440
38394718	38394741	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCACGATGGAGTCAGCTTCAGG	SPRED3	ENSG00000188766	0.24768947644736433	[3]	[2,3]	6	hSpCas9	positive selection	4173441
38394776	38394799	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCAGGTCGCACCTGAGCGGAGG	SPRED3	ENSG00000188766	0.09632747647398232	[0]	[0,0]	2	hSpCas9	positive selection	4173442
38392275	38392298	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.28924980439801373	[3]	[2,1]	-6	hSpCas9	positive selection	4173443
38392267	38392290	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGAGACCCCCTGCCCTCTGACGG	SPRED3	ENSG00000188766	0.9828049792293163	[2]	[1,1,0,3]	7	hSpCas9	positive selection	4237462
38394718	38394741	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCACGATGGAGTCAGCTTCAGG	SPRED3	ENSG00000188766	1.201482227030767	[4]	[2,2,4,4]	8	hSpCas9	positive selection	4237463
38394776	38394799	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCAGGTCGCACCTGAGCGGAGG	SPRED3	ENSG00000188766	-0.2371966700365623	[1]	[0,0,0,0]	-3	hSpCas9	positive selection	4237464
38392275	38392298	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.6497785628181867	[3]	[0,2,0,3]	4	hSpCas9	positive selection	4237465
38395562	38395585	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.1771168773623494	[2]	[2,1]	3	hSpCas9	positive selection	4300420
38395498	38395521	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.36987012257278057	[2]	[2,0]	-7	hSpCas9	positive selection	4300421
38392100	38392123	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.2930414741538183	[3]	[4,3]	6	hSpCas9	positive selection	4300422
38394645	38394668	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.07329804545161323	[0]	[0,0]	1	hSpCas9	positive selection	4364675
38392017	38392040	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.5150764446171477	[3]	[2,0]	-8	hSpCas9	positive selection	4364676
38392275	38392298	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.3901637404769146	[3]	[4,3]	7	hSpCas9	positive selection	4364677
38390390	38390412	19	+	27760321	OCIAML3	viability	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	-0.2528224042963302	[526,492]	[373,283]	-3	hSpCas9	negative selection	4442915
38390431	38390453	19	-	27760321	OCIAML3	viability	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.24715333687167962	[1011,907]	[682,1159]	3	hSpCas9	negative selection	4442916
38392017	38392039	19	-	27760321	OCIAML3	viability	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.1490518945631133	[641,543]	[421,409]	-1	hSpCas9	negative selection	4442917
38392100	38392122	19	-	27760321	OCIAML3	viability	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.36288079029180165	[1098,873]	[749,1293]	4	hSpCas9	negative selection	4442918
38395498	38395520	19	-	27760321	OCIAML3	viability	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.4041121041351698	[481,381]	[195,328]	-4	hSpCas9	negative selection	4442919
38390390	38390412	19	+	27760321	OCIAML2	viability	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	0.29333790738663856	[526,492]	[482,535]	4	hSpCas9	negative selection	4526378
38390431	38390453	19	-	27760321	OCIAML2	viability	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.5083419658389714	[1011,907]	[1007,1228]	7	hSpCas9	negative selection	4526379
38392017	38392039	19	-	27760321	OCIAML2	viability	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.24304652508466051	[641,543]	[497,654]	3	hSpCas9	negative selection	4526380
38392100	38392122	19	-	27760321	OCIAML2	viability	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.34161419826774897	[1098,873]	[967,1053]	4	hSpCas9	negative selection	4526381
38395498	38395520	19	-	27760321	OCIAML2	viability	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.29542001580961125	[481,381]	[200,390]	-4	hSpCas9	negative selection	4526382
38390390	38390412	19	+	27760321	MV411	viability	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	0.35425720684131456	[526,492]	[256,690]	2	hSpCas9	negative selection	4609841
38390431	38390453	19	-	27760321	MV411	viability	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.858787057639488	[1011,907]	[826,1628]	6	hSpCas9	negative selection	4609842
38392017	38392039	19	-	27760321	MV411	viability	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.7352938997082579	[641,543]	[850,345]	5	hSpCas9	negative selection	4609843
38392100	38392122	19	-	27760321	MV411	viability	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.38587782484561584	[1098,873]	[667,1111]	2	hSpCas9	negative selection	4609844
38395498	38395520	19	-	27760321	MV411	viability	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.07047789482508583	[481,381]	[266,273]	0	hSpCas9	negative selection	4609845
38390390	38390412	19	+	27760321	HL60	viability	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	-0.3514440923138115	[526,492]	[366,283]	-4	hSpCas9	negative selection	4693304
38390431	38390453	19	-	27760321	HL60	viability	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.04708398546365111	[1011,907]	[834,781]	0	hSpCas9	negative selection	4693305
38392017	38392039	19	-	27760321	HL60	viability	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.0037628697192848004	[641,543]	[479,482]	0	hSpCas9	negative selection	4693306
38392100	38392122	19	-	27760321	HL60	viability	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.6088679870974021	[1098,873]	[1204,1238]	7	hSpCas9	negative selection	4693307
38395498	38395520	19	-	27760321	HL60	viability	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.6270530171667836	[481,381]	[528,554]	7	hSpCas9	negative selection	4693308
38390390	38390412	19	+	27760321	HT1080	viability	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	-0.07209823768613122	[492,384]	[152,180]	0	hSpCas9	negative selection	4776767
38390431	38390453	19	-	27760321	HT1080	viability	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.46843146239589895	[907,708]	[237,672]	2	hSpCas9	negative selection	4776768
38392017	38392039	19	-	27760321	HT1080	viability	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.29719882171946294	[543,424]	[261,209]	1	hSpCas9	negative selection	4776769
38392100	38392122	19	-	27760321	HT1080	viability	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.4144849793316647	[873,681]	[340,491]	2	hSpCas9	negative selection	4776770
38395498	38395520	19	-	27760321	HT1080	viability	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	1.4389113333686632	[381,297]	[497,223]	7	hSpCas9	negative selection	4776771
38390390	38390412	19	+	27760321	HT29	viability after 7 days	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	-0.2202357243666056	[492,384]	[351,469,607]	-3	hSpCas9	negative selection	4860230
38390431	38390453	19	-	27760321	HT29	viability after 7 days	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	-0.36562199319775446	[907,708]	[930,826,682]	-5	hSpCas9	negative selection	4860231
38392017	38392039	19	-	27760321	HT29	viability after 7 days	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.11980740976652099	[543,424]	[819,484,742]	1	hSpCas9	negative selection	4860232
38392100	38392122	19	-	27760321	HT29	viability after 7 days	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.3502499012856699	[873,681]	[1536,1306,1024]	5	hSpCas9	negative selection	4860233
38395498	38395520	19	-	27760321	HT29	viability after 7 days	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.1632747640886849	[381,297]	[453,316,407]	-2	hSpCas9	negative selection	4860234
38390390	38390412	19	+	27760321	HT29	viability after 25 days	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	-0.42536109948798795	[492,384]	[221,385,538]	-4	hSpCas9	negative selection	4943693
38390431	38390453	19	-	27760321	HT29	viability after 25 days	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	-1.053305840317525	[907,708]	[358,436,555]	-6	hSpCas9	negative selection	4943694
38392017	38392039	19	-	27760321	HT29	viability after 25 days	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.4065523656964349	[543,424]	[545,791,890]	4	hSpCas9	negative selection	4943695
38392100	38392122	19	-	27760321	HT29	viability after 25 days	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.4574692223057173	[873,681]	[1036,1330,1313]	5	hSpCas9	negative selection	4943696
38395498	38395520	19	-	27760321	HT29	viability after 25 days	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.25855338476023854	[381,297]	[237,436,301]	-3	hSpCas9	negative selection	4943697
38390390	38390412	19	+	27760321	HT29	viability after 22 days	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	0.04022465337156739	[492,384]	[573,383,606]	0	hSpCas9	negative selection	5027156
38390431	38390453	19	-	27760321	HT29	viability after 22 days	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	-1.0218141361928417	[907,708]	[434,555,389]	-6	hSpCas9	negative selection	5027157
38392017	38392039	19	-	27760321	HT29	viability after 22 days	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.25522526744928126	[543,424]	[726,609,666]	2	hSpCas9	negative selection	5027158
38392100	38392122	19	-	27760321	HT29	viability after 22 days	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.47576378352780835	[873,681]	[1473,1142,1127]	5	hSpCas9	negative selection	5027159
38395498	38395520	19	-	27760321	HT29	viability after 22 days	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.6252673998027973	[381,297]	[181,265,318]	-5	hSpCas9	negative selection	5027160
38390390	38390412	19	+	27760321	HT29	viability after 19 days	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	-0.0639682521722647	[492,384]	[311,442,660]	0	hSpCas9	negative selection	5110619
38390431	38390453	19	-	27760321	HT29	viability after 19 days	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	-0.5837673144145307	[907,708]	[559,840,449]	-5	hSpCas9	negative selection	5110620
38392017	38392039	19	-	27760321	HT29	viability after 19 days	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.28761146485124117	[543,424]	[677,810,544]	2	hSpCas9	negative selection	5110621
38392100	38392122	19	-	27760321	HT29	viability after 19 days	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.7653228973265218	[873,681]	[1039,1647,1787]	7	hSpCas9	negative selection	5110622
38395498	38395520	19	-	27760321	HT29	viability after 19 days	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.6903619377505461	[381,297]	[165,203,340]	-5	hSpCas9	negative selection	5110623
38390390	38390412	19	+	27760321	HT29	viability after 16 days	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	-0.34965360058498507	[492,384]	[421,299,439]	-4	hSpCas9	negative selection	5194082
38390431	38390453	19	-	27760321	HT29	viability after 16 days	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	-0.40408314713736804	[907,708]	[667,998,373]	-4	hSpCas9	negative selection	5194083
38392017	38392039	19	-	27760321	HT29	viability after 16 days	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.23095148119829795	[543,424]	[479,741,668]	2	hSpCas9	negative selection	5194084
38392100	38392122	19	-	27760321	HT29	viability after 16 days	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.43808895592857233	[873,681]	[1072,1122,1332]	5	hSpCas9	negative selection	5194085
38395498	38395520	19	-	27760321	HT29	viability after 16 days	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.10576362323227011	[381,297]	[178,695,159]	-1	hSpCas9	negative selection	5194086
38390390	38390412	19	+	27760321	HT29	viability after 13 days	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	-0.0033318212680372716	[492,384]	[478,513,529]	0	hSpCas9	negative selection	5277545
38390431	38390453	19	-	27760321	HT29	viability after 13 days	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	-0.4293782860207608	[907,708]	[498,844,742]	-5	hSpCas9	negative selection	5277546
38392017	38392039	19	-	27760321	HT29	viability after 13 days	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.07634991546040276	[543,424]	[522,627,624]	0	hSpCas9	negative selection	5277547
38392100	38392122	19	-	27760321	HT29	viability after 13 days	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.23045545114449695	[873,681]	[983,1412,795]	3	hSpCas9	negative selection	5277548
38395498	38395520	19	-	27760321	HT29	viability after 13 days	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.0185970152089241	[381,297]	[406,416,375]	0	hSpCas9	negative selection	5277549
38390390	38390412	19	+	27760321	HT29	viability after 10 days	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	-0.21475161372112012	[492,384]	[606,373,433]	-3	hSpCas9	negative selection	5361008
38390431	38390453	19	-	27760321	HT29	viability after 10 days	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	-0.5095376695174834	[907,708]	[1079,618,431]	-6	hSpCas9	negative selection	5361009
38392017	38392039	19	-	27760321	HT29	viability after 10 days	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.017294593123885926	[543,424]	[390,817,632]	0	hSpCas9	negative selection	5361010
38392100	38392122	19	-	27760321	HT29	viability after 10 days	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.5582250506615518	[873,681]	[1278,1424,1582]	7	hSpCas9	negative selection	5361011
38395498	38395520	19	-	27760321	HT29	viability after 10 days	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.04155314749150809	[381,297]	[584,357,366]	0	hSpCas9	negative selection	5361012
38390390	38390412	19	+	27760321	MOLM13	viability	AGCGTGTGTCGGGTCCGAGGGG	SPRED3	ENSG00000188766	0.1943835996970336	[526,492]	[390,276]	1	hSpCas9	negative selection	5444471
38390431	38390453	19	-	27760321	MOLM13	viability	GATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.5289037045400831	[1011,907]	[819,746]	3	hSpCas9	negative selection	5444472
38392017	38392039	19	-	27760321	MOLM13	viability	TCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.20396432970320078	[641,543]	[497,286]	1	hSpCas9	negative selection	5444473
38392100	38392122	19	-	27760321	MOLM13	viability	TGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	1.523240092751402	[1098,873]	[2590,737]	9	hSpCas9	negative selection	5444474
38395498	38395520	19	-	27760321	MOLM13	viability	GTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.8434469075228479	[481,381]	[235,48]	-5	hSpCas9	negative selection	5444475
38389822	38389845	19	+	27661255	K562	viability	GCCTGGACGACAGGGTGCGGAGG	SPRED3	ENSG00000188766	0.00834710621354473	[202,286]	[247,150]	0	dCas9-KRAB	negative selection	5514097
38389827	38389850	19	+	27661255	K562	viability	GACGACAGGGTGCGGAGGCAGGG	SPRED3	ENSG00000188766	-0.09162997678175215	[654,758]	[621,448]	-3	dCas9-KRAB	negative selection	5514098
38389898	38389921	19	+	27661255	K562	viability	GCAGGCACCCAGCTGTGAGGGGG	SPRED3	ENSG00000188766	0.07913394431166287	[1003,1039]	[917,813]	2	dCas9-KRAB	negative selection	5514099
38390135	38390158	19	+	27661255	K562	viability	GTGGCCATGGGGTTGAAGGTGGG	SPRED3	ENSG00000188766	-1.53964380294485	[7,49]	[10,4]	-9	dCas9-KRAB	negative selection	5514100
38390187	38390210	19	+	27661255	K562	viability	GACGTGAGAGATGAAGTTGGAGG	SPRED3	ENSG00000188766	0.14363693523109283	[907,1041]	[861,854]	5	dCas9-KRAB	negative selection	5514101
38390218	38390241	19	+	27661255	K562	viability	GGGTTGAGGGAACATTCCATGGG	SPRED3	ENSG00000188766	0.26165585896441	[1190,1656]	[1488,1241]	8	dCas9-KRAB	negative selection	5514102
38390234	38390257	19	-	27661255	K562	viability	GCTCAAACCCTGCTCTCCCATGG	SPRED3	ENSG00000188766	0.016039318863150687	[65,64]	[53,51]	0	dCas9-KRAB	negative selection	5514103
38395562	38395585	19	+	27260156	BXPC3	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.28225137466547806	[278]	[294,342,383,408]	6	hSpCas9	negative selection	5572880
38395498	38395521	19	-	27260156	BXPC3	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.3205564963731742	[448]	[562,533,647,604]	7	hSpCas9	negative selection	5572881
38392100	38392123	19	-	27260156	BXPC3	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.024232667048403544	[897]	[979,892,1026,908]	0	hSpCas9	negative selection	5572882
38394645	38394668	19	-	27260156	BXPC3	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.8446160516653669	[27]	[33,42,108,23]	9	hSpCas9	negative selection	5637135
38392017	38392040	19	-	27260156	BXPC3	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.036886438166678914	[749]	[614,725,741,1018]	-1	hSpCas9	negative selection	5637136
38392275	38392298	19	-	27260156	BXPC3	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.03098535248273393	[923]	[774,1070,1137,976]	0	hSpCas9	negative selection	5637137
38395562	38395585	19	+	27260156	A673	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.15037191458962107	[278]	[340,257,332,564]	3	hSpCas9	negative selection	5694131
38395498	38395521	19	-	27260156	A673	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.45517654772359817	[448]	[840,803,632,684]	8	hSpCas9	negative selection	5694132
38392100	38392123	19	-	27260156	A673	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.1797698731419003	[897]	[1461,1035,1163,1255]	4	hSpCas9	negative selection	5694133
38394645	38394668	19	-	27260156	A673	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.8413082745843221	[27]	[71,43,88,35]	9	hSpCas9	negative selection	5758386
38392017	38392040	19	-	27260156	A673	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.06890743686132317	[749]	[1157,829,883,931]	1	hSpCas9	negative selection	5758387
38392275	38392298	19	-	27260156	A673	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.00012421552574681805	[923]	[1083,924,1215,1217]	0	hSpCas9	negative selection	5758388
38395562	38395585	19	+	27260156	A375	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.3587918726887629	[278]	[373,620,489,234]	5	hSpCas9	negative selection	5815382
38395498	38395521	19	-	27260156	A375	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.7033867372611607	[448]	[981,1087,559,819]	9	hSpCas9	negative selection	5815383
38392100	38392123	19	-	27260156	A375	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.13339546727467677	[897]	[1046,1339,965,1256]	2	hSpCas9	negative selection	5815384
38394645	38394668	19	-	27260156	A375	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.6818599937526959	[27]	[46,51,89,23]	8	hSpCas9	negative selection	5879637
38392017	38392040	19	-	27260156	A375	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.19834532526801052	[749]	[712,1250,1009,1066]	3	hSpCas9	negative selection	5879638
38392275	38392298	19	-	27260156	A375	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.24215950589552193	[923]	[998,726,1036,863]	-3	hSpCas9	negative selection	5879639
38395562	38395585	19	+	27260156	COLO741	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.19198283406797523	[278]	[256,469,475]	4	hSpCas9	negative selection	5936633
38395498	38395521	19	-	27260156	COLO741	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.49185901729099013	[448]	[1024,750,670]	8	hSpCas9	negative selection	5936634
38392100	38392123	19	-	27260156	COLO741	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.4033490994161234	[897]	[1971,1268,1357]	8	hSpCas9	negative selection	5936635
38394645	38394668	19	-	27260156	COLO741	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.4517758105150693	[27]	[75,38,34]	8	hSpCas9	negative selection	6000888
38392017	38392040	19	-	27260156	COLO741	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.015251773132627156	[749]	[1077,1056,790]	0	hSpCas9	negative selection	6000889
38392275	38392298	19	-	27260156	COLO741	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.006593825986304869	[923]	[1358,1084,1129]	0	hSpCas9	negative selection	6000890
38395562	38395585	19	+	27260156	CAL120	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.6433603892412418	[278]	[1073,389,247]	8	hSpCas9	negative selection	6057884
38395498	38395521	19	-	27260156	CAL120	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.4883397565604092	[448]	[1037,660,691]	7	hSpCas9	negative selection	6057885
38392100	38392123	19	-	27260156	CAL120	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.5795670708930493	[897]	[1558,1963,1472]	8	hSpCas9	negative selection	6057886
38394645	38394668	19	-	27260156	CAL120	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.6466756392189628	[27]	[23,78,55]	8	hSpCas9	negative selection	6122139
38392017	38392040	19	-	27260156	CAL120	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.03372802413351639	[749]	[964,708,1065]	0	hSpCas9	negative selection	6122140
38392275	38392298	19	-	27260156	CAL120	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.36103353442976194	[923]	[2270,1071,1210]	5	hSpCas9	negative selection	6122141
38395562	38395585	19	+	27260156	CADOES1	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.3007342016859593	[278]	[322,323,273,358]	5	hSpCas9	negative selection	6179135
38395498	38395521	19	-	27260156	CADOES1	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.6399462382743415	[448]	[526,707,725,641]	9	hSpCas9	negative selection	6179136
38392100	38392123	19	-	27260156	CADOES1	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.24164659911505126	[897]	[1023,1065,1025,827]	4	hSpCas9	negative selection	6179137
38394645	38394668	19	-	27260156	CADOES1	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-0.3160432640819746	[27]	[30,15,31,3]	-5	hSpCas9	negative selection	6243390
38392017	38392040	19	-	27260156	CADOES1	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.004550635820491533	[749]	[670,688,736,683]	0	hSpCas9	negative selection	6243391
38392275	38392298	19	-	27260156	CADOES1	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.1098975504505062	[923]	[825,1078,779,1028]	2	hSpCas9	negative selection	6243392
38395562	38395585	19	+	27260156	EWS502	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.26634804159156067	[278]	[425,310,273,404]	5	hSpCas9	negative selection	6300386
38395498	38395521	19	-	27260156	EWS502	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.6602796743387641	[448]	[665,740,723,892]	9	hSpCas9	negative selection	6300387
38392100	38392123	19	-	27260156	EWS502	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.19052683093202416	[897]	[791,1407,1102,1054]	3	hSpCas9	negative selection	6300388
38394645	38394668	19	-	27260156	EWS502	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-1.041270825128552	[27]	[7,0,6,44]	-9	hSpCas9	negative selection	6364641
38392017	38392040	19	-	27260156	EWS502	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.16072612473845505	[749]	[738,757,791,1311]	3	hSpCas9	negative selection	6364642
38392275	38392298	19	-	27260156	EWS502	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.10519929836293618	[923]	[999,1298,884,1013]	1	hSpCas9	negative selection	6364643
38395562	38395585	19	+	27260156	EW8	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.011328224140437548	[278]	[246,202,220,242]	0	hSpCas9	negative selection	6421637
38395498	38395521	19	-	27260156	EW8	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.27993847457581167	[448]	[357,453,462,477]	5	hSpCas9	negative selection	6421638
38392100	38392123	19	-	27260156	EW8	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	-0.6126360588441466	[897]	[543,356,464,544]	-8	hSpCas9	negative selection	6421639
38394645	38394668	19	-	27260156	EW8	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-0.437306200912869	[27]	[3,37,20,1]	-7	hSpCas9	negative selection	6485892
38392017	38392040	19	-	27260156	EW8	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.3917433316774285	[749]	[615,499,308,469]	-6	hSpCas9	negative selection	6485893
38392275	38392298	19	-	27260156	EW8	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.3107716885011419	[923]	[649,635,540,601]	-5	hSpCas9	negative selection	6485894
38395562	38395585	19	+	27260156	CORL105	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.2644123404086476	[278]	[349,444,337,424]	5	hSpCas9	negative selection	6542888
38395498	38395521	19	-	27260156	CORL105	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.4932927174159307	[448]	[804,632,898,651]	8	hSpCas9	negative selection	6542889
38392100	38392123	19	-	27260156	CORL105	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.2412829819191059	[897]	[1302,1193,1334,1155]	4	hSpCas9	negative selection	6542890
38394645	38394668	19	-	27260156	CORL105	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-0.4357834340248763	[27]	[21,44,20,7]	-7	hSpCas9	negative selection	6607143
38392017	38392040	19	-	27260156	CORL105	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.09913317242195219	[749]	[815,826,767,858]	-2	hSpCas9	negative selection	6607144
38392275	38392298	19	-	27260156	CORL105	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.3464143034304066	[923]	[854,704,979,885]	-6	hSpCas9	negative selection	6607145
38395562	38395585	19	+	27260156	HS294T	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.18017353662281266	[278]	[88,180,120,93]	2	hSpCas9	negative selection	6664139
38395498	38395521	19	-	27260156	HS294T	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.878214663040013	[448]	[282,367,352,263]	9	hSpCas9	negative selection	6664140
38392100	38392123	19	-	27260156	HS294T	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.09860029410479132	[897]	[244,344,387,550]	1	hSpCas9	negative selection	6664141
38394645	38394668	19	-	27260156	HS294T	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.899507477754776	[27]	[15,46,2,12]	9	hSpCas9	negative selection	6728394
38392017	38392040	19	-	27260156	HS294T	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.3915228228383039	[749]	[162,196,298,232]	-5	hSpCas9	negative selection	6728395
38392275	38392298	19	-	27260156	HS294T	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.2049580687274568	[923]	[295,303,321,319]	-3	hSpCas9	negative selection	6728396
38395562	38395585	19	+	27260156	HCC44	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.48791857892887597	[278]	[351,530,400,453]	7	hSpCas9	negative selection	6785390
38395498	38395521	19	-	27260156	HCC44	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.7723050851901626	[448]	[968,903,837,753]	9	hSpCas9	negative selection	6785391
38392100	38392123	19	-	27260156	HCC44	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.6936007545195583	[897]	[1470,1677,1999,1454]	9	hSpCas9	negative selection	6785392
38394645	38394668	19	-	27260156	HCC44	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.7383919461473192	[27]	[55,0,53,105]	9	hSpCas9	negative selection	6849645
38392017	38392040	19	-	27260156	HCC44	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.023147323104408035	[749]	[920,546,849,1160]	0	hSpCas9	negative selection	6849646
38392275	38392298	19	-	27260156	HCC44	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.28642231969198506	[923]	[1424,1074,1463,1200]	4	hSpCas9	negative selection	6849647
38395562	38395585	19	+	27260156	G402	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	-0.10298041571238892	[278]	[270,220,286,467]	-1	hSpCas9	negative selection	6906641
38395498	38395521	19	-	27260156	G402	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.17494495237961089	[448]	[592,832,575,484]	2	hSpCas9	negative selection	6906642
38392100	38392123	19	-	27260156	G402	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.3142011596602422	[897]	[1335,1471,1218,1416]	4	hSpCas9	negative selection	6906643
38394645	38394668	19	-	27260156	G402	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-0.01181463968119889	[27]	[61,3,0,68]	0	hSpCas9	negative selection	6970896
38392017	38392040	19	-	27260156	G402	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.12209690492010217	[749]	[1253,899,973,888]	1	hSpCas9	negative selection	6970897
38392275	38392298	19	-	27260156	G402	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.5684085150382234	[923]	[1305,953,417,464]	-6	hSpCas9	negative selection	6970898
38395562	38395585	19	+	27260156	L33	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.30272349083287364	[278]	[237,171,177,436]	6	hSpCas9	negative selection	7027892
38395498	38395521	19	-	27260156	L33	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.4776935494962954	[448]	[585,220,378,771]	8	hSpCas9	negative selection	7027893
38392100	38392123	19	-	27260156	L33	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.2616905984699561	[897]	[1185,361,708,1105]	5	hSpCas9	negative selection	7027894
38394645	38394668	19	-	27260156	L33	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-0.30846244907919296	[27]	[23,3,24,16]	-6	hSpCas9	negative selection	7092147
38392017	38392040	19	-	27260156	L33	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.21325704118644628	[749]	[976,389,493,760]	4	hSpCas9	negative selection	7092148
38392275	38392298	19	-	27260156	L33	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.1052863238167856	[923]	[1015,456,643,820]	2	hSpCas9	negative selection	7092149
38395562	38395585	19	+	27260156	K562	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.0163153980703008	[278]	[456,228,236,109]	0	hSpCas9	negative selection	7149143
38395498	38395521	19	-	27260156	K562	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.2674023891215471	[448]	[261,794,339,513]	3	hSpCas9	negative selection	7149144
38392100	38392123	19	-	27260156	K562	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.1080375703417612	[897]	[770,1481,624,608]	1	hSpCas9	negative selection	7149145
38394645	38394668	19	-	27260156	K562	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-0.957773834438763	[27]	[6,11,31,0]	-8	hSpCas9	negative selection	7213398
38392017	38392040	19	-	27260156	K562	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.2847344166307624	[749]	[1292,1011,251,740]	3	hSpCas9	negative selection	7213399
38392275	38392298	19	-	27260156	K562	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.033209548334147576	[923]	[815,896,890,624]	0	hSpCas9	negative selection	7213400
38395562	38395585	19	+	27260156	HT29	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.1497596118552288	[278]	[348,435,448,282]	3	hSpCas9	negative selection	7270394
38395498	38395521	19	-	27260156	HT29	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.03319233614912474	[448]	[496,366,619,617]	0	hSpCas9	negative selection	7270395
38392100	38392123	19	-	27260156	HT29	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.19000746026825566	[897]	[1118,1396,1461,1024]	3	hSpCas9	negative selection	7270396
38394645	38394668	19	-	27260156	HT29	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.5159483741082842	[27]	[35,79,30,48]	8	hSpCas9	negative selection	7334649
38392017	38392040	19	-	27260156	HT29	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.10604168079339049	[749]	[878,1403,746,451]	-2	hSpCas9	negative selection	7334650
38392275	38392298	19	-	27260156	HT29	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.16081339273362516	[923]	[1097,959,1086,884]	-3	hSpCas9	negative selection	7334651
38395562	38395585	19	+	27260156	MHHES1	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.3928319073129192	[278]	[455,515,470,251]	7	hSpCas9	negative selection	7391645
38395498	38395521	19	-	27260156	MHHES1	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.5778862138130489	[448]	[823,734,796,671]	8	hSpCas9	negative selection	7391646
38392100	38392123	19	-	27260156	MHHES1	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.2439280803736804	[897]	[1591,1425,1181,741]	4	hSpCas9	negative selection	7391647
38394645	38394668	19	-	27260156	MHHES1	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.5894471920412836	[27]	[46,71,54,22]	8	hSpCas9	negative selection	7455900
38392017	38392040	19	-	27260156	MHHES1	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.08910330852220483	[749]	[1053,986,734,501]	-2	hSpCas9	negative selection	7455901
38392275	38392298	19	-	27260156	MHHES1	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.1853636547641666	[923]	[1236,1460,1032,1041]	3	hSpCas9	negative selection	7455902
38395562	38395585	19	+	27260156	MEWO	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.21439625277822716	[278]	[324,251,335]	5	hSpCas9	negative selection	7512896
38395498	38395521	19	-	27260156	MEWO	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.5244750205347477	[448]	[703,579,547]	9	hSpCas9	negative selection	7512897
38392100	38392123	19	-	27260156	MEWO	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.3050164849553957	[897]	[1270,978,908]	6	hSpCas9	negative selection	7512898
38394645	38394668	19	-	27260156	MEWO	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-0.12359028614315726	[27]	[12,21,34]	-3	hSpCas9	negative selection	7577151
38392017	38392040	19	-	27260156	MEWO	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.2981699086618919	[749]	[805,455,495]	-6	hSpCas9	negative selection	7577152
38392275	38392298	19	-	27260156	MEWO	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.06943710643464196	[923]	[1070,866,814]	1	hSpCas9	negative selection	7577153
38395562	38395585	19	+	27260156	LNCAPCLONEFGC	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.29228026877616375	[278]	[285,396,245,293]	4	hSpCas9	negative selection	7634147
38395498	38395521	19	-	27260156	LNCAPCLONEFGC	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.7245729516338238	[448]	[615,744,751,582]	9	hSpCas9	negative selection	7634148
38392100	38392123	19	-	27260156	LNCAPCLONEFGC	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.08225052292423507	[897]	[697,758,1136,900]	1	hSpCas9	negative selection	7634149
38394645	38394668	19	-	27260156	LNCAPCLONEFGC	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.7425434562051456	[27]	[46,18,20,80]	9	hSpCas9	negative selection	7698402
38392017	38392040	19	-	27260156	LNCAPCLONEFGC	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.07096917645949596	[749]	[796,665,796,607]	1	hSpCas9	negative selection	7698403
38392275	38392298	19	-	27260156	LNCAPCLONEFGC	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.15976217938648862	[923]	[709,742,1087,506]	-3	hSpCas9	negative selection	7698404
38395562	38395585	19	+	27260156	PANC0327	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.46247859715056105	[278]	[294,479,226,341]	6	hSpCas9	negative selection	7755398
38395498	38395521	19	-	27260156	PANC0327	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	-0.12614957337143792	[448]	[533,228,301,427]	-2	hSpCas9	negative selection	7755399
38392100	38392123	19	-	27260156	PANC0327	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.33420949113620535	[897]	[973,833,1126,1106]	5	hSpCas9	negative selection	7755400
38394645	38394668	19	-	27260156	PANC0327	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	1.792525718003822	[27]	[74,144,19,95]	9	hSpCas9	negative selection	7819653
38392017	38392040	19	-	27260156	PANC0327	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.21669329728786346	[749]	[719,953,759,634]	3	hSpCas9	negative selection	7819654
38392275	38392298	19	-	27260156	PANC0327	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.16812866331520104	[923]	[873,577,961,1314]	2	hSpCas9	negative selection	7819655
38395562	38395585	19	+	27260156	NCIH2009	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.0009497611797476546	[278]	[577,261,368]	0	hSpCas9	negative selection	7876649
38395498	38395521	19	-	27260156	NCIH2009	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.7717595490592033	[448]	[1415,1045,817]	9	hSpCas9	negative selection	7876650
38392100	38392123	19	-	27260156	NCIH2009	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.14262427433187652	[897]	[1370,1160,1621]	2	hSpCas9	negative selection	7876651
38394645	38394668	19	-	27260156	NCIH2009	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-0.10805137306268264	[27]	[95,15,8]	-1	hSpCas9	negative selection	7940904
38392017	38392040	19	-	27260156	NCIH2009	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.2305200708974524	[749]	[1305,1080,1316]	3	hSpCas9	negative selection	7940905
38392275	38392298	19	-	27260156	NCIH2009	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.09917844608036464	[923]	[1800,987,1446]	1	hSpCas9	negative selection	7940906
38395562	38395585	19	+	27260156	NCIH1373	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.95311622401216	[278]	[1116,330,750,80]	8	hSpCas9	negative selection	7997900
38395498	38395521	19	-	27260156	NCIH1373	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.690550342944654	[448]	[1025,823,745,176]	7	hSpCas9	negative selection	7997901
38392100	38392123	19	-	27260156	NCIH1373	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.25005909373752677	[897]	[1534,1444,881,245]	2	hSpCas9	negative selection	7997902
38394645	38394668	19	-	27260156	NCIH1373	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-0.11420834573131522	[27]	[15,25,2,18]	-1	hSpCas9	negative selection	8062155
38392017	38392040	19	-	27260156	NCIH1373	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.10614255374807469	[749]	[1060,695,793,295]	1	hSpCas9	negative selection	8062156
38392275	38392298	19	-	27260156	NCIH1373	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.2075687093279871	[923]	[1116,879,709,240]	-2	hSpCas9	negative selection	8062157
38395562	38395585	19	+	27260156	PATU8902	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.7537526390090536	[278]	[612,989,605,388]	7	hSpCas9	negative selection	8119151
38395498	38395521	19	-	27260156	PATU8902	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.29296375329742547	[448]	[541,992,717,828]	3	hSpCas9	negative selection	8119152
38392100	38392123	19	-	27260156	PATU8902	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.2602727596464679	[897]	[1120,1877,1178,1943]	2	hSpCas9	negative selection	8119153
38394645	38394668	19	-	27260156	PATU8902	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.34129793272359477	[27]	[3,2,65,129]	3	hSpCas9	negative selection	8183406
38392017	38392040	19	-	27260156	PATU8902	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.22405855427341043	[749]	[891,1672,358,772]	-2	hSpCas9	negative selection	8183407
38392275	38392298	19	-	27260156	PATU8902	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.09018086895367727	[923]	[1182,1874,770,1099]	-1	hSpCas9	negative selection	8183408
38395562	38395585	19	+	27260156	PANC1	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	-0.23912949822968954	[278]	[173,339,173,156]	-4	hSpCas9	negative selection	8240402
38395498	38395521	19	-	27260156	PANC1	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.3063094179038571	[448]	[549,556,427,392]	5	hSpCas9	negative selection	8240403
38392100	38392123	19	-	27260156	PANC1	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.358057670128863	[897]	[957,1246,995,818]	6	hSpCas9	negative selection	8240404
38394645	38394668	19	-	27260156	PANC1	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.45117746374679335	[27]	[31,61,17,25]	7	hSpCas9	negative selection	8304657
38392017	38392040	19	-	27260156	PANC1	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.2519810849013814	[749]	[745,884,849,623]	4	hSpCas9	negative selection	8304658
38392275	38392298	19	-	27260156	PANC1	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.04109204871875538	[923]	[624,1105,683,887]	0	hSpCas9	negative selection	8304659
38395562	38395585	19	+	27260156	PANC0813	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.08902653390125415	[278]	[439,311,266,380]	1	hSpCas9	negative selection	8361653
38395498	38395521	19	-	27260156	PANC0813	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.81747029087015	[448]	[1349,796,847,768]	9	hSpCas9	negative selection	8361654
38392100	38392123	19	-	27260156	PANC0813	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.3986860527411561	[897]	[1385,1527,1616,1048]	6	hSpCas9	negative selection	8361655
38394645	38394668	19	-	27260156	PANC0813	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.417092086494526	[27]	[128,8,30,15]	6	hSpCas9	negative selection	8425908
38392017	38392040	19	-	27260156	PANC0813	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.047485871037962535	[749]	[878,669,1031,831]	-1	hSpCas9	negative selection	8425909
38392275	38392298	19	-	27260156	PANC0813	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.01703130346396442	[923]	[873,1063,1392,947]	0	hSpCas9	negative selection	8425910
38395562	38395585	19	+	27260156	RDES	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.3439534303877336	[278]	[391,342,411,490]	5	hSpCas9	negative selection	8482904
38395498	38395521	19	-	27260156	RDES	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.5160193942930503	[448]	[579,689,972,735]	8	hSpCas9	negative selection	8482905
38392100	38392123	19	-	27260156	RDES	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.1714475735207338	[897]	[857,1228,1237,1389]	2	hSpCas9	negative selection	8482906
38394645	38394668	19	-	27260156	RDES	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.15783135603959142	[27]	[36,32,10,64]	2	hSpCas9	negative selection	8547159
38392017	38392040	19	-	27260156	RDES	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.026363829326116917	[749]	[675,757,880,1138]	0	hSpCas9	negative selection	8547160
38392275	38392298	19	-	27260156	RDES	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.13126875242962122	[923]	[992,1100,1546,1011]	2	hSpCas9	negative selection	8547161
38395562	38395585	19	+	27260156	PC3	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.30800114895350655	[278]	[281,219,466,452]	6	hSpCas9	negative selection	8604155
38395498	38395521	19	-	27260156	PC3	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.4434025958061525	[448]	[379,607,938,679]	8	hSpCas9	negative selection	8604156
38392100	38392123	19	-	27260156	PC3	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.3637583353966217	[897]	[772,1201,1501,1315]	7	hSpCas9	negative selection	8604157
38394645	38394668	19	-	27260156	PC3	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.13397426107050592	[27]	[28,41,23,19]	3	hSpCas9	negative selection	8668410
38392017	38392040	19	-	27260156	PC3	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.12264334922139641	[749]	[534,510,1132,739]	-3	hSpCas9	negative selection	8668411
38392275	38392298	19	-	27260156	PC3	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.0013472996033212503	[923]	[645,861,1436,962]	0	hSpCas9	negative selection	8668412
38395562	38395585	19	+	27260156	PATU8988T	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	-0.020641874960984907	[278]	[221,321,105,433]	0	hSpCas9	negative selection	8725406
38395498	38395521	19	-	27260156	PATU8988T	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.23038386769608535	[448]	[419,735,390,511]	4	hSpCas9	negative selection	8725407
38392100	38392123	19	-	27260156	PATU8988T	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	-0.3298100988800795	[897]	[458,773,698,849]	-5	hSpCas9	negative selection	8725408
38394645	38394668	19	-	27260156	PATU8988T	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.008314751807853682	[27]	[6,29,13,60]	0	hSpCas9	negative selection	8789661
38392017	38392040	19	-	27260156	PATU8988T	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.207715483598997	[749]	[521,837,571,595]	-4	hSpCas9	negative selection	8789662
38392275	38392298	19	-	27260156	PATU8988T	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.2884084734814547	[923]	[680,801,677,773]	-5	hSpCas9	negative selection	8789663
38395562	38395585	19	+	27260156	T47D	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.2536843637601356	[278]	[412,292,444,406]	5	hSpCas9	negative selection	8846657
38395498	38395521	19	-	27260156	T47D	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.3658444939059492	[448]	[691,641,641,724]	7	hSpCas9	negative selection	8846658
38392100	38392123	19	-	27260156	T47D	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.19718674706848993	[897]	[1285,1035,1233,1256]	4	hSpCas9	negative selection	8846659
38394645	38394668	19	-	27260156	T47D	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.3213336464930894	[27]	[18,29,39,75]	6	hSpCas9	negative selection	8910912
38392017	38392040	19	-	27260156	T47D	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.002250004291456831	[749]	[1052,734,870,841]	0	hSpCas9	negative selection	8910913
38392275	38392298	19	-	27260156	T47D	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.14555698867507338	[923]	[1287,1229,1024,1219]	3	hSpCas9	negative selection	8910914
38395562	38395585	19	+	27260156	SU8686	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.39229811983318374	[278]	[337,370,433,299]	6	hSpCas9	negative selection	8967908
38395498	38395521	19	-	27260156	SU8686	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.4046520050014645	[448]	[516,588,724,522]	6	hSpCas9	negative selection	8967909
38392100	38392123	19	-	27260156	SU8686	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.09221307985614369	[897]	[975,798,1000,1046]	1	hSpCas9	negative selection	8967910
38394645	38394668	19	-	27260156	SU8686	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.2988265254372826	[27]	[52,15,17,51]	5	hSpCas9	negative selection	9032163
38392017	38392040	19	-	27260156	SU8686	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-4.5730580798042375e-05	[749]	[646,601,1010,745]	0	hSpCas9	negative selection	9032164
38392275	38392298	19	-	27260156	SU8686	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.44228632129859635	[923]	[577,613,752,785]	-6	hSpCas9	negative selection	9032165
38395562	38395585	19	+	27260156	SKES1	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.3122004882039571	[278]	[352,332,366,326]	6	hSpCas9	negative selection	9089159
38395498	38395521	19	-	27260156	SKES1	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.691039124737009	[448]	[993,714,664,566]	9	hSpCas9	negative selection	9089160
38392100	38392123	19	-	27260156	SKES1	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.1673887673503246	[897]	[1113,1252,915,800]	3	hSpCas9	negative selection	9089161
38394645	38394668	19	-	27260156	SKES1	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-0.6131478938792592	[27]	[9,11,11,34]	-8	hSpCas9	negative selection	9153414
38392017	38392040	19	-	27260156	SKES1	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	0.03413324984668831	[749]	[819,731,899,622]	0	hSpCas9	negative selection	9153415
38392275	38392298	19	-	27260156	SKES1	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.08070922368794242	[923]	[816,1059,892,737]	-2	hSpCas9	negative selection	9153416
38395562	38395585	19	+	27260156	TOV112D	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	-0.043335782644565946	[278]	[182,290,239,364]	-1	hSpCas9	negative selection	9210410
38395498	38395521	19	-	27260156	TOV112D	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.42040086768609497	[448]	[685,717,508,530]	7	hSpCas9	negative selection	9210411
38392100	38392123	19	-	27260156	TOV112D	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	-0.012123196587535023	[897]	[987,1312,784,599]	0	hSpCas9	negative selection	9210412
38394645	38394668	19	-	27260156	TOV112D	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	1.5002206329319758	[27]	[42,103,13,156]	9	hSpCas9	negative selection	9274665
38392017	38392040	19	-	27260156	TOV112D	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.2101842492616604	[749]	[757,834,659,404]	-4	hSpCas9	negative selection	9274666
38392275	38392298	19	-	27260156	TOV112D	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.09124272358652274	[923]	[746,1195,995,611]	-2	hSpCas9	negative selection	9274667
38395562	38395585	19	+	27260156	TC71	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.20248066637122553	[278]	[294,454,240,392]	5	hSpCas9	negative selection	9331661
38395498	38395521	19	-	27260156	TC71	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.36666096724913966	[448]	[575,628,656,619]	8	hSpCas9	negative selection	9331662
38392100	38392123	19	-	27260156	TC71	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.1705947020384947	[897]	[1103,934,1177,1114]	4	hSpCas9	negative selection	9331663
38394645	38394668	19	-	27260156	TC71	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	0.508939793781265	[27]	[68,9,48,41]	9	hSpCas9	negative selection	9395916
38392017	38392040	19	-	27260156	TC71	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.05645440883088215	[749]	[688,803,840,756]	-1	hSpCas9	negative selection	9395917
38392275	38392298	19	-	27260156	TC71	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.06427912377351863	[923]	[913,902,897,1084]	-2	hSpCas9	negative selection	9395918
38395562	38395585	19	+	27260156	TC32	viability	GCCGCGGCTACGAGGATTACCGG	SPRED3	ENSG00000188766	0.3766377128563793	[278]	[279,359,384,320]	6	hSpCas9	negative selection	9452912
38395498	38395521	19	-	27260156	TC32	viability	GGTTCCGGAATCCCCGTGAACGG	SPRED3	ENSG00000188766	0.8271821126290135	[448]	[802,686,773,698]	9	hSpCas9	negative selection	9452913
38392100	38392123	19	-	27260156	TC32	viability	CTGCTCACCTCGACCCAGTGCGG	SPRED3	ENSG00000188766	0.07755288918517056	[897]	[801,746,1017,1035]	1	hSpCas9	negative selection	9452914
38394645	38394668	19	-	27260156	TC32	viability	AGGAGGAGTCGCTGTCCACGTGG	SPRED3	ENSG00000188766	-0.7281446380325871	[27]	[8,0,46,17]	-8	hSpCas9	negative selection	9517167
38392017	38392040	19	-	27260156	TC32	viability	GTCCAAACTTGCAGTCACCCAGG	SPRED3	ENSG00000188766	-0.03644712267387962	[749]	[720,399,966,779]	0	hSpCas9	negative selection	9517168
38392275	38392298	19	-	27260156	TC32	viability	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.1316150400704592	[923]	[956,707,1264,963]	2	hSpCas9	negative selection	9517169
38388489	38388512	19	+	27869803	HPAFII	viability after 27 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	0.2721757400782562	[247]	[211,111,NaN]	2	hSpCas9	negative selection	9567559
38390464	38390487	19	-	27869803	HPAFII	viability after 27 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-2.8172533831238424	[38]	[3,1,NaN]	-9	hSpCas9	negative selection	9567560
38392077	38392100	19	+	27869803	HPAFII	viability after 27 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-0.21642170667297322	[88]	[6,67,NaN]	-2	hSpCas9	negative selection	9567561
38392275	38392298	19	-	27869803	HPAFII	viability after 27 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-2.0253153104972537	[125]	[24,8,NaN]	-8	hSpCas9	negative selection	9567562
38394630	38394653	19	+	27869803	HPAFII	viability after 27 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.18799820055813543	[430]	[253,152,NaN]	-1	hSpCas9	negative selection	9567563
38395824	38395847	19	-	27869803	HPAFII	viability after 27 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	0.40710668010626105	[349]	[489,38,NaN]	3	hSpCas9	negative selection	9567564
38388489	38388512	19	+	27869803	HPAFII	viability after 15 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	-1.0300302321333061	[247]	[177,100,NaN]	-8	hSpCas9	negative selection	9650008
38390464	38390487	19	-	27869803	HPAFII	viability after 15 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-1.5363259969874483	[38]	[19,10,NaN]	-8	hSpCas9	negative selection	9650009
38392077	38392100	19	+	27869803	HPAFII	viability after 15 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.035522225669386565	[88]	[118,84,NaN]	0	hSpCas9	negative selection	9650010
38392275	38392298	19	-	27869803	HPAFII	viability after 15 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.7417503970489884	[125]	[51,98,NaN]	-7	hSpCas9	negative selection	9650011
38394630	38394653	19	+	27869803	HPAFII	viability after 15 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.1534252181472755	[430]	[524,348,NaN]	-2	hSpCas9	negative selection	9650012
38395824	38395847	19	-	27869803	HPAFII	viability after 15 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	0.09279416455434153	[349]	[521,325,NaN]	1	hSpCas9	negative selection	9650013
38388489	38388512	19	+	27869803	ASPC1	viability after 36 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	1.7516520672823463	[415]	[1095,289,215]	9	hSpCas9	negative selection	9732457
38390464	38390487	19	-	27869803	ASPC1	viability after 36 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.9163813214206991	[167]	[85,19,0]	-7	hSpCas9	negative selection	9732458
38392077	38392100	19	+	27869803	ASPC1	viability after 36 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-1.241339237941339	[240]	[57,10,38]	-8	hSpCas9	negative selection	9732459
38392275	38392298	19	-	27869803	ASPC1	viability after 36 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.8855725593761435	[360]	[82,119,15]	-7	hSpCas9	negative selection	9732460
38394630	38394653	19	+	27869803	ASPC1	viability after 36 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.25737907391095316	[812]	[248,114,323]	-3	hSpCas9	negative selection	9732461
38395824	38395847	19	-	27869803	ASPC1	viability after 36 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	-0.2279099257242873	[1004]	[184,394,300]	-2	hSpCas9	negative selection	9732462
38388489	38388512	19	+	27869803	PATU8988S	viability after 35 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	1.650236776504804	[463]	[400,772,NaN]	9	hSpCas9	negative selection	9814906
38390464	38390487	19	-	27869803	PATU8988S	viability after 35 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-1.5055465585200305	[154]	[15,27,NaN]	-8	hSpCas9	negative selection	9814907
38392077	38392100	19	+	27869803	PATU8988S	viability after 35 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-0.817856557736726	[139]	[25,37,NaN]	-7	hSpCas9	negative selection	9814908
38392275	38392298	19	-	27869803	PATU8988S	viability after 35 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.4178736631368746	[284]	[85,220,NaN]	5	hSpCas9	negative selection	9814909
38394630	38394653	19	+	27869803	PATU8988S	viability after 35 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.3285308297116094	[819]	[261,263,NaN]	-3	hSpCas9	negative selection	9814910
38395824	38395847	19	-	27869803	PATU8988S	viability after 35 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	-0.41199888916484234	[965]	[251,332,NaN]	-4	hSpCas9	negative selection	9814911
38388489	38388512	19	+	27869803	PATU8988S	viability after 31 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	1.1849576752836848	[463]	[267,614,NaN]	9	hSpCas9	negative selection	9897355
38390464	38390487	19	-	27869803	PATU8988S	viability after 31 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-1.3410356876333789	[154]	[8,43,NaN]	-8	hSpCas9	negative selection	9897356
38392077	38392100	19	+	27869803	PATU8988S	viability after 31 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-1.4467806406373809	[139]	[12,29,NaN]	-8	hSpCas9	negative selection	9897357
38392275	38392298	19	-	27869803	PATU8988S	viability after 31 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	0.677393136444234	[284]	[91,295,NaN]	7	hSpCas9	negative selection	9897358
38394630	38394653	19	+	27869803	PATU8988S	viability after 31 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	-0.2490709644969205	[819]	[297,245,NaN]	-3	hSpCas9	negative selection	9897359
38395824	38395847	19	-	27869803	PATU8988S	viability after 31 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	-0.3922122137115736	[965]	[179,437,NaN]	-4	hSpCas9	negative selection	9897360
38388489	38388512	19	+	27869803	HPAFII	viability after 35 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	0.14765356440500296	[247]	[179,92,NaN]	0	hSpCas9	negative selection	9979804
38390464	38390487	19	-	27869803	HPAFII	viability after 35 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-1.9145305962219603	[38]	[8,0,NaN]	-7	hSpCas9	negative selection	9979805
38392077	38392100	19	+	27869803	HPAFII	viability after 35 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-1.6688810490747656	[88]	[0,28,NaN]	-7	hSpCas9	negative selection	9979806
38392275	38392298	19	-	27869803	HPAFII	viability after 35 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-0.9554703721527925	[125]	[54,7,NaN]	-5	hSpCas9	negative selection	9979807
38394630	38394653	19	+	27869803	HPAFII	viability after 35 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	0.40444378266223335	[430]	[348,220,NaN]	2	hSpCas9	negative selection	9979808
38395824	38395847	19	-	27869803	HPAFII	viability after 35 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	0.9429493444677811	[349]	[548,105,NaN]	6	hSpCas9	negative selection	9979809
38388489	38388512	19	+	27869803	HPAFII	viability after 31 days	TTAGAGACCAATGGCGCAGATGG	SPRED3	ENSG00000188766	-0.5653595072349584	[247]	[139,43,NaN]	-4	hSpCas9	negative selection	10062253
38390464	38390487	19	-	27869803	HPAFII	viability after 31 days	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-1.5926293493597918	[38]	[12,0,NaN]	-7	hSpCas9	negative selection	10062254
38392077	38392100	19	+	27869803	HPAFII	viability after 31 days	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-0.45592959021390445	[88]	[0,74,NaN]	-3	hSpCas9	negative selection	10062255
38392275	38392298	19	-	27869803	HPAFII	viability after 31 days	GACACTCACCGTCAGAGGGCAGG	SPRED3	ENSG00000188766	-1.0750536883685093	[125]	[34,31,NaN]	-6	hSpCas9	negative selection	10062256
38394630	38394653	19	+	27869803	HPAFII	viability after 31 days	CAATCTCCTCCAGTCCCACGTGG	SPRED3	ENSG00000188766	0.4708591848820296	[430]	[306,365,NaN]	3	hSpCas9	negative selection	10062257
38395824	38395847	19	-	27869803	HPAFII	viability after 31 days	CACGCCCGTCTGCTCTGCGACGG	SPRED3	ENSG00000188766	0.5868360245361014	[349]	[462,111,NaN]	4	hSpCas9	negative selection	10062258
38394768	38394791	19	-	28162770	P31FUJ	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-2.595372283799087	[71]	[13]	-8	hSpCas9	negative selection	10242383
38390308	38390331	19	+	28162770	P31FUJ	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.16026996336767363	[545]	[716]	1	hSpCas9	negative selection	10242384
38392041	38392064	19	+	28162770	P31FUJ	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	-0.454188912889681	[477]	[409]	-4	hSpCas9	negative selection	10242385
38392242	38392265	19	-	28162770	P31FUJ	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	0.18628212792716736	[88]	[118]	2	hSpCas9	negative selection	10242386
38390377	38390400	19	-	28162770	P31FUJ	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.7354889358582831	[137]	[269]	8	hSpCas9	negative selection	10242387
38390431	38390454	19	-	28162770	P31FUJ	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.8768222867601198	[151]	[327]	8	hSpCas9	negative selection	10242388
38390464	38390487	19	-	28162770	P31FUJ	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	1.5556936903919094	[21]	[75]	9	hSpCas9	negative selection	10242389
38392077	38392100	19	+	28162770	P31FUJ	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.7820710720671515	[192]	[389]	8	hSpCas9	negative selection	10242390
38394662	38394685	19	-	28162770	P31FUJ	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	0.06836733030618627	[223]	[275]	0	hSpCas9	negative selection	10242391
38394687	38394710	19	+	28162770	P31FUJ	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	0.1110616804406297	[482]	[612]	1	hSpCas9	negative selection	10242392
38394768	38394791	19	-	28162770	TF1	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10411749
38390308	38390331	19	+	28162770	TF1	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10411750
38392041	38392064	19	+	28162770	TF1	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10411751
38392242	38392265	19	-	28162770	TF1	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10411752
38390377	38390400	19	-	28162770	TF1	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10411753
38390431	38390454	19	-	28162770	TF1	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10411754
38390464	38390487	19	-	28162770	TF1	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10411755
38392077	38392100	19	+	28162770	TF1	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10411756
38394662	38394685	19	-	28162770	TF1	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10411757
38394687	38394710	19	+	28162770	TF1	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	NaN	[NaN]	[163]	1	hSpCas9	negative selection	10411758
38394768	38394791	19	-	28162770	SKM1	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-0.23703919730084944	[25]	[38]	-2	hSpCas9	negative selection	10581115
38390308	38390331	19	+	28162770	SKM1	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.3816872846360344	[121]	[280]	3	hSpCas9	negative selection	10581116
38392041	38392064	19	+	28162770	SKM1	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	-0.5324950808270207	[152]	[186]	-4	hSpCas9	negative selection	10581117
38392242	38392265	19	-	28162770	SKM1	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	-0.17666657932136764	[38]	[60]	-1	hSpCas9	negative selection	10581118
38390377	38390400	19	-	28162770	SKM1	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.29535525261615325	[58]	[127]	3	hSpCas9	negative selection	10581119
38390431	38390454	19	-	28162770	SKM1	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.8577390274512504	[53]	[172]	7	hSpCas9	negative selection	10581120
38390464	38390487	19	-	28162770	SKM1	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	2.7629608026991503	[2]	[35]	9	hSpCas9	negative selection	10581121
38392077	38392100	19	+	28162770	SKM1	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.4937741698837617	[46]	[116]	5	hSpCas9	negative selection	10581122
38394662	38394685	19	-	28162770	SKM1	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	1.0746205621326859	[46]	[174]	8	hSpCas9	negative selection	10581123
38394687	38394710	19	+	28162770	SKM1	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	0.6571661386765539	[98]	[275]	6	hSpCas9	negative selection	10581124
38394768	38394791	19	-	28162770	SKM1	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-0.23703919730084944	[25]	[38]	-2	hSpCas9	negative selection	10750481
38390308	38390331	19	+	28162770	SKM1	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.3816872846360344	[121]	[280]	3	hSpCas9	negative selection	10750482
38392041	38392064	19	+	28162770	SKM1	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	-0.5324950808270207	[152]	[186]	-4	hSpCas9	negative selection	10750483
38392242	38392265	19	-	28162770	SKM1	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	-0.17666657932136764	[38]	[60]	-1	hSpCas9	negative selection	10750484
38390377	38390400	19	-	28162770	SKM1	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.29535525261615325	[58]	[127]	3	hSpCas9	negative selection	10750485
38390431	38390454	19	-	28162770	SKM1	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.8577390274512504	[53]	[172]	7	hSpCas9	negative selection	10750486
38390464	38390487	19	-	28162770	SKM1	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	2.7629608026991503	[2]	[35]	9	hSpCas9	negative selection	10750487
38392077	38392100	19	+	28162770	SKM1	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.4937741698837617	[46]	[116]	5	hSpCas9	negative selection	10750488
38394662	38394685	19	-	28162770	SKM1	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	1.0746205621326859	[46]	[174]	8	hSpCas9	negative selection	10750489
38394687	38394710	19	+	28162770	SKM1	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	0.6571661386765539	[98]	[275]	6	hSpCas9	negative selection	10750490
38394768	38394791	19	-	28162770	PL21	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-3.9697853869529927	[71]	[1]	-9	hSpCas9	negative selection	10919847
38390308	38390331	19	+	28162770	PL21	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	-0.23928204341648285	[357]	[131]	-2	hSpCas9	negative selection	10919848
38392041	38392064	19	+	28162770	PL21	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	0.24823390269036527	[471]	[243]	2	hSpCas9	negative selection	10919849
38392242	38392265	19	-	28162770	PL21	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	0.9426433921969564	[103]	[86]	7	hSpCas9	negative selection	10919850
38390377	38390400	19	-	28162770	PL21	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.4920956296256236	[213]	[130]	4	hSpCas9	negative selection	10919851
38390431	38390454	19	-	28162770	PL21	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.738235510172502	[218]	[158]	6	hSpCas9	negative selection	10919852
38390464	38390487	19	-	28162770	PL21	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-1.1217884803980427	[19]	[3]	-6	hSpCas9	negative selection	10919853
38392077	38392100	19	+	28162770	PL21	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.7186067034235696	[147]	[105]	6	hSpCas9	negative selection	10919854
38394662	38394685	19	-	28162770	PL21	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	0.623351045213864	[175]	[117]	5	hSpCas9	negative selection	10919855
38394687	38394710	19	+	28162770	PL21	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	1.0842404947295186	[284]	[262]	8	hSpCas9	negative selection	10919856
38394768	38394791	19	-	28162770	P31FUJ	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-2.595372283799087	[71]	[13]	-8	hSpCas9	negative selection	11089213
38390308	38390331	19	+	28162770	P31FUJ	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.16026996336767363	[545]	[716]	1	hSpCas9	negative selection	11089214
38392041	38392064	19	+	28162770	P31FUJ	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	-0.454188912889681	[477]	[409]	-4	hSpCas9	negative selection	11089215
38392242	38392265	19	-	28162770	P31FUJ	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	0.18628212792716736	[88]	[118]	2	hSpCas9	negative selection	11089216
38390377	38390400	19	-	28162770	P31FUJ	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.7354889358582831	[137]	[269]	8	hSpCas9	negative selection	11089217
38390431	38390454	19	-	28162770	P31FUJ	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.8768222867601198	[151]	[327]	8	hSpCas9	negative selection	11089218
38390464	38390487	19	-	28162770	P31FUJ	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	1.5556936903919094	[21]	[75]	9	hSpCas9	negative selection	11089219
38392077	38392100	19	+	28162770	P31FUJ	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.7820710720671515	[192]	[389]	8	hSpCas9	negative selection	11089220
38394662	38394685	19	-	28162770	P31FUJ	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	0.06836733030618627	[223]	[275]	0	hSpCas9	negative selection	11089221
38394687	38394710	19	+	28162770	P31FUJ	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	0.1110616804406297	[482]	[612]	1	hSpCas9	negative selection	11089222
38394768	38394791	19	-	28162770	OCIAML5	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-1.7188000400005328	[30]	[16]	-7	hSpCas9	negative selection	11258579
38390308	38390331	19	+	28162770	OCIAML5	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.1756784196189073	[205]	[419]	1	hSpCas9	negative selection	11258580
38392041	38392064	19	+	28162770	OCIAML5	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	-0.05778025105381457	[300]	[521]	0	hSpCas9	negative selection	11258581
38392242	38392265	19	-	28162770	OCIAML5	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	0.027639195418291296	[74]	[137]	0	hSpCas9	negative selection	11258582
38390377	38390400	19	-	28162770	OCIAML5	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.6538243588659604	[99]	[283]	6	hSpCas9	negative selection	11258583
38390431	38390454	19	-	28162770	OCIAML5	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	1.0845080489943693	[92]	[355]	8	hSpCas9	negative selection	11258584
38390464	38390487	19	-	28162770	OCIAML5	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-1.267104070142841	[27]	[20]	-6	hSpCas9	negative selection	11258585
38392077	38392100	19	+	28162770	OCIAML5	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.6689841660369661	[99]	[286]	6	hSpCas9	negative selection	11258586
38394662	38394685	19	-	28162770	OCIAML5	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	0.5105035085207112	[97]	[251]	4	hSpCas9	negative selection	11258587
38394687	38394710	19	+	28162770	OCIAML5	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	-0.3369942819452306	[288]	[412]	-2	hSpCas9	negative selection	11258588
38394768	38394791	19	-	28162770	EOL1	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-1.2251993479341474	[141]	[31]	-7	hSpCas9	negative selection	11427945
38390308	38390331	19	+	28162770	EOL1	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.3993783556916358	[448]	[311]	3	hSpCas9	negative selection	11427946
38392041	38392064	19	+	28162770	EOL1	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	0.13076404540448383	[819]	[472]	1	hSpCas9	negative selection	11427947
38392242	38392265	19	-	28162770	EOL1	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	0.5619776921858263	[233]	[181]	5	hSpCas9	negative selection	11427948
38390377	38390400	19	-	28162770	EOL1	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	1.2825451211654186	[315]	[404]	9	hSpCas9	negative selection	11427949
38390431	38390454	19	-	28162770	EOL1	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.7546227701282222	[332]	[295]	6	hSpCas9	negative selection	11427950
38390464	38390487	19	-	28162770	EOL1	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.036978080614829434	[36]	[18]	0	hSpCas9	negative selection	11427951
38392077	38392100	19	+	28162770	EOL1	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.5356942040953457	[181]	[138]	5	hSpCas9	negative selection	11427952
38394662	38394685	19	-	28162770	EOL1	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	0.05287186854607409	[257]	[140]	0	hSpCas9	negative selection	11427953
38394687	38394710	19	+	28162770	EOL1	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	0.2840079229544984	[515]	[330]	2	hSpCas9	negative selection	11427954
38394768	38394791	19	-	28162770	MOLM13	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	0.10176148274668151	[115]	[89]	0	hSpCas9	negative selection	11597311
38390308	38390331	19	+	28162770	MOLM13	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.48905399154262086	[405]	[411]	3	hSpCas9	negative selection	11597312
38392041	38392064	19	+	28162770	MOLM13	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	0.485429962853714	[653]	[661]	3	hSpCas9	negative selection	11597313
38392242	38392265	19	-	28162770	MOLM13	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	-0.3156187985586575	[209]	[121]	-2	hSpCas9	negative selection	11597314
38390377	38390400	19	-	28162770	MOLM13	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	1.1766580838801328	[278]	[455]	8	hSpCas9	negative selection	11597315
38390431	38390454	19	-	28162770	MOLM13	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.9897418384110968	[256]	[368]	7	hSpCas9	negative selection	11597316
38390464	38390487	19	-	28162770	MOLM13	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-1.4390012140639392	[44]	[11]	-6	hSpCas9	negative selection	11597317
38392077	38392100	19	+	28162770	MOLM13	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.42724739704723297	[179]	[174]	3	hSpCas9	negative selection	11597318
38394662	38394685	19	-	28162770	MOLM13	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	-0.09430181151791922	[219]	[148]	0	hSpCas9	negative selection	11597319
38394687	38394710	19	+	28162770	MOLM13	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	0.07576018957577824	[478]	[364]	0	hSpCas9	negative selection	11597320
38394768	38394791	19	-	28162770	HEL	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-1.0112653131504505	[106]	[33]	-6	hSpCas9	negative selection	11766677
38390308	38390331	19	+	28162770	HEL	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.5960455965523155	[470]	[455]	5	hSpCas9	negative selection	11766678
38392041	38392064	19	+	28162770	HEL	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	0.7578238528592562	[565]	[612]	6	hSpCas9	negative selection	11766679
38392242	38392265	19	-	28162770	HEL	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	0.06555368187092009	[184]	[123]	0	hSpCas9	negative selection	11766680
38390377	38390400	19	-	28162770	HEL	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.5767412732261169	[245]	[234]	5	hSpCas9	negative selection	11766681
38390431	38390454	19	-	28162770	HEL	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	1.364363880032077	[207]	[342]	9	hSpCas9	negative selection	11766682
38390464	38390487	19	-	28162770	HEL	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	1.3141160845389863	[26]	[42]	9	hSpCas9	negative selection	11766683
38392077	38392100	19	+	28162770	HEL	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.5198820842148236	[195]	[179]	4	hSpCas9	negative selection	11766684
38394662	38394685	19	-	28162770	HEL	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	-0.14401712887738038	[225]	[130]	-1	hSpCas9	negative selection	11766685
38394687	38394710	19	+	28162770	HEL	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	0.5037624188515467	[391]	[355]	4	hSpCas9	negative selection	11766686
38394768	38394791	19	-	28162770	MV411	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-0.5522637987313934	[46]	[26]	-4	hSpCas9	negative selection	11936043
38390308	38390331	19	+	28162770	MV411	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.4541908483416328	[317]	[366]	4	hSpCas9	negative selection	11936044
38392041	38392064	19	+	28162770	MV411	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	-0.1675999484960684	[443]	[332]	-1	hSpCas9	negative selection	11936045
38392242	38392265	19	-	28162770	MV411	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	-0.46716023035497645	[127]	[77]	-3	hSpCas9	negative selection	11936046
38390377	38390400	19	-	28162770	MV411	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.695490107289582	[161]	[220]	6	hSpCas9	negative selection	11936047
38390431	38390454	19	-	28162770	MV411	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.06047461898392535	[180]	[158]	0	hSpCas9	negative selection	11936048
38390464	38390487	19	-	28162770	MV411	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.3805936718302667	[16]	[10]	-3	hSpCas9	negative selection	11936049
38392077	38392100	19	+	28162770	MV411	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-0.16759994849606852	[143]	[107]	-1	hSpCas9	negative selection	11936050
38394662	38394685	19	-	28162770	MV411	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	0.14721010304412102	[148]	[138]	1	hSpCas9	negative selection	11936051
38394687	38394710	19	+	28162770	MV411	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	-0.39739640591577974	[368]	[235]	-3	hSpCas9	negative selection	11936052
38394768	38394791	19	-	28162770	MONOMAC1	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	0.17333160288556182	[40]	[52]	1	hSpCas9	negative selection	12105409
38390308	38390331	19	+	28162770	MONOMAC1	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.5734813068176791	[203]	[347]	5	hSpCas9	negative selection	12105410
38392041	38392064	19	+	28162770	MONOMAC1	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	-0.2979657559103346	[295]	[275]	-3	hSpCas9	negative selection	12105411
38392242	38392265	19	-	28162770	MONOMAC1	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	-0.4695627018706451	[121]	[100]	-4	hSpCas9	negative selection	12105412
38390377	38390400	19	-	28162770	MONOMAC1	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.9612252368571785	[137]	[307]	8	hSpCas9	negative selection	12105413
38390431	38390454	19	-	28162770	MONOMAC1	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	0.2593414476001895	[128]	[176]	2	hSpCas9	negative selection	12105414
38390464	38390487	19	-	28162770	MONOMAC1	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.027111845617241226	[15]	[17]	0	hSpCas9	negative selection	12105415
38392077	38392100	19	+	28162770	MONOMAC1	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	-0.47189668829013703	[97]	[80]	-4	hSpCas9	negative selection	12105416
38394662	38394685	19	-	28162770	MONOMAC1	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	0.053506614591043174	[115]	[137]	0	hSpCas9	negative selection	12105417
38394687	38394710	19	+	28162770	MONOMAC1	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	0.07189816021392459	[243]	[293]	0	hSpCas9	negative selection	12105418
38394768	38394791	19	-	28162770	OCIAML2	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	0.21119421473158395	[11]	[76]	2	hSpCas9	negative selection	12274775
38390308	38390331	19	+	28162770	OCIAML2	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	0.047218479620458	[54]	[314]	0	hSpCas9	negative selection	12274776
38392041	38392064	19	+	28162770	OCIAML2	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	-0.25879118206645435	[97]	[453]	-2	hSpCas9	negative selection	12274777
38392242	38392265	19	-	28162770	OCIAML2	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	0.4708179924027259	[21]	[168]	4	hSpCas9	negative selection	12274778
38390377	38390400	19	-	28162770	OCIAML2	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.3029103838231991	[36]	[252]	3	hSpCas9	negative selection	12274779
38390431	38390454	19	-	28162770	OCIAML2	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	-0.5010034742856799	[35]	[140]	-4	hSpCas9	negative selection	12274780
38390464	38390487	19	-	28162770	OCIAML2	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.5961607073260202	[2]	[10]	-4	hSpCas9	negative selection	12274781
38392077	38392100	19	+	28162770	OCIAML2	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.23563897170112846	[18]	[123]	2	hSpCas9	negative selection	12274782
38394662	38394685	19	-	28162770	OCIAML2	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	-0.09559039389523649	[31]	[165]	-1	hSpCas9	negative selection	12274783
38394687	38394710	19	+	28162770	OCIAML2	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	-0.600852402650742	[83]	[306]	-4	hSpCas9	negative selection	12274784
38394768	38394791	19	-	28162770	OCIAML3	viability	GCACCTGAGCGGAGGAGCGGCGG	SPRED3	ENSG00000188766	-0.5236183124327651	[29]	[62]	-4	hSpCas9	negative selection	12444141
38390308	38390331	19	+	28162770	OCIAML3	viability	GCGGGTCCGAGCTGTGGTGATGG	SPRED3	ENSG00000188766	-0.1743535129749494	[116]	[312]	-1	hSpCas9	negative selection	12444142
38392041	38392064	19	+	28162770	OCIAML3	viability	GACGTTTCAGAGCCCTGCAGAGG	SPRED3	ENSG00000188766	0.580166834119507	[112]	[509]	5	hSpCas9	negative selection	12444143
38392242	38392265	19	-	28162770	OCIAML3	viability	AGTATCCTGGGAAGGAGAGGAGG	SPRED3	ENSG00000188766	-0.3657386526510459	[34]	[81]	-3	hSpCas9	negative selection	12444144
38390377	38390400	19	-	28162770	OCIAML3	viability	GACACACGCTCACCTGGCTGAGG	SPRED3	ENSG00000188766	0.8726919787771732	[71]	[397]	7	hSpCas9	negative selection	12444145
38390431	38390454	19	-	28162770	OCIAML3	viability	GGATGACGTAGTGCCCCTGGCGG	SPRED3	ENSG00000188766	-0.022101292428453267	[36]	[109]	0	hSpCas9	negative selection	12444146
38390464	38390487	19	-	28162770	OCIAML3	viability	GGCTCACTTTCTGGTCCCGGAGG	SPRED3	ENSG00000188766	-0.9565777197088714	[8]	[13]	-6	hSpCas9	negative selection	12444147
38392077	38392100	19	+	28162770	OCIAML3	viability	GAAGAGCCTGCTGGCTGCGCTGG	SPRED3	ENSG00000188766	0.6935689497724224	[33]	[165]	6	hSpCas9	negative selection	12444148
38394662	38394685	19	-	28162770	OCIAML3	viability	CTGGCGGCTGTGACTGGAGGAGG	SPRED3	ENSG00000188766	-0.009045139603007	[49]	[149]	0	hSpCas9	negative selection	12444149
38394687	38394710	19	+	28162770	OCIAML3	viability	GACTCCTCCCAGCGCCGCTGCGG	SPRED3	ENSG00000188766	-0.8174458718121624	[114]	[196]	-6	hSpCas9	negative selection	12444150