Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6720
• Symbol:SREBF1
• Description:sterol regulatory element binding transcription factor 1

DataSource: http://genomecrispr.dkfz.de/#!/results/SREBF1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
17820131	17820154	17	+	26472758	Jiyoye	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	156220
17820368	17820391	17	+	26472758	Jiyoye	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	0.08193455257767533	[108]	[86]	0	hSpCas9	negative selection	156221
17820115	17820138	17	+	26472758	Jiyoye	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	2.3593468564152587	[22]	[88]	9	hSpCas9	negative selection	156222
17820089	17820112	17	+	26472758	Jiyoye	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	0.2579493727313972	[172]	[155]	2	hSpCas9	negative selection	156223
17819339	17819362	17	+	26472758	Jiyoye	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	0.8862221207064906	[258]	[360]	6	hSpCas9	negative selection	156224
17817836	17817859	17	-	26472758	Jiyoye	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-1.656150553862956	[162]	[38]	-8	hSpCas9	negative selection	156225
17816299	17816322	17	-	26472758	Jiyoye	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	0.6410634416801508	[124]	[146]	5	hSpCas9	negative selection	156226
17815941	17815964	17	-	26472758	Jiyoye	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	0.887801222412294	[42]	[59]	6	hSpCas9	negative selection	156227
17836786	17836809	17	+	26472758	Jiyoye	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	-1.0826298861749426	[131]	[46]	-6	hSpCas9	negative selection	156228
17820462	17820485	17	+	26472758	Jiyoye	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	0.01957111235014186	[190]	[145]	0	hSpCas9	negative selection	156229
17820131	17820154	17	+	26472758	KBM7	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	-2.510438429076113	[5,16]	[0,0]	-9	hSpCas9	negative selection	347338
17820368	17820391	17	+	26472758	KBM7	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-0.9422362842489318	[651,443]	[119,142]	-6	hSpCas9	negative selection	347339
17820115	17820138	17	+	26472758	KBM7	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	-0.849287896524853	[322,234]	[90,54]	-6	hSpCas9	negative selection	347340
17820089	17820112	17	+	26472758	KBM7	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-0.8268316084823035	[605,243]	[130,87]	-6	hSpCas9	negative selection	347341
17819339	17819362	17	+	26472758	KBM7	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-0.7890671692548847	[1642,949]	[356,333]	-6	hSpCas9	negative selection	347342
17817836	17817859	17	-	26472758	KBM7	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-1.4147198052202157	[1118,997]	[129,236]	-7	hSpCas9	negative selection	347343
17816299	17816322	17	-	26472758	KBM7	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-1.596109407917434	[540,475]	[60,94]	-8	hSpCas9	negative selection	347344
17815941	17815964	17	-	26472758	KBM7	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	0.9021537879336332	[264,177]	[178,202]	8	hSpCas9	negative selection	347345
17836786	17836809	17	+	26472758	KBM7	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	-0.8739391573003005	[266,365]	[65,97]	-6	hSpCas9	negative selection	347346
17820462	17820485	17	+	26472758	KBM7	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	-0.1467192354073751	[659,467]	[131,329]	-1	hSpCas9	negative selection	347347
17820131	17820154	17	+	26472758	Raji	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	538456
17820368	17820391	17	+	26472758	Raji	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-0.36654765295881275	[249]	[44]	-3	hSpCas9	negative selection	538457
17820115	17820138	17	+	26472758	Raji	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	0.7137196868873227	[133]	[50]	6	hSpCas9	negative selection	538458
17820089	17820112	17	+	26472758	Raji	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-0.633583989350103	[360]	[53]	-5	hSpCas9	negative selection	538459
17819339	17819362	17	+	26472758	Raji	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-0.42476226690410845	[589]	[101]	-3	hSpCas9	negative selection	538460
17817836	17817859	17	-	26472758	Raji	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-2.229651451903971	[383]	[18]	-9	hSpCas9	negative selection	538461
17816299	17816322	17	-	26472758	Raji	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-1.4128732759597413	[217]	[18]	-7	hSpCas9	negative selection	538462
17815941	17815964	17	-	26472758	Raji	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	1.1427166084858802	[120]	[61]	8	hSpCas9	negative selection	538463
17836786	17836809	17	+	26472758	Raji	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	0.2484274168287829	[184]	[50]	2	hSpCas9	negative selection	538464
17820462	17820485	17	+	26472758	Raji	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	-0.6921730161235974	[368]	[52]	-5	hSpCas9	negative selection	538465
17820131	17820154	17	+	26472758	K562	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	-3.3405437730547085	[11]	[0]	-8	hSpCas9	negative selection	729574
17820368	17820391	17	+	26472758	K562	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-1.7142222425724956	[446]	[114]	-7	hSpCas9	negative selection	729575
17820115	17820138	17	+	26472758	K562	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	-3.698095777672793	[245]	[15]	-9	hSpCas9	negative selection	729576
17820089	17820112	17	+	26472758	K562	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-2.9826501808794745	[308]	[32]	-8	hSpCas9	negative selection	729577
17819339	17819362	17	+	26472758	K562	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-2.9255062737758655	[1097]	[121]	-8	hSpCas9	negative selection	729578
17817836	17817859	17	-	26472758	K562	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-3.1340928955872824	[831]	[79]	-8	hSpCas9	negative selection	729579
17816299	17816322	17	-	26472758	K562	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-3.555282621847722	[375]	[26]	-8	hSpCas9	negative selection	729580
17815941	17815964	17	-	26472758	K562	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	1.0826676576698346	[131]	[235]	8	hSpCas9	negative selection	729581
17836786	17836809	17	+	26472758	K562	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	-2.077509367220915	[174]	[34]	-7	hSpCas9	negative selection	729582
17820462	17820485	17	+	26472758	K562	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	-1.6881944326036789	[480]	[125]	-7	hSpCas9	negative selection	729583
17819210	17819233	17	+	26627737	DLD1	viability	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	-0.4099699362994036	[592]	[231,116,77]	-4	hSpCas9	negative selection	796359
17819338	17819361	17	+	26627737	DLD1	viability	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-0.4758273540905078	[1322]	[314,410,187]	-5	hSpCas9	negative selection	796360
17819638	17819661	17	+	26627737	DLD1	viability	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-3.1721376775202863	[495]	[30,2,16]	-9	hSpCas9	negative selection	796361
17820280	17820303	17	+	26627737	DLD1	viability	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	-0.8044523659657626	[538]	[102,88,96]	-6	hSpCas9	negative selection	796362
17823591	17823614	17	-	26627737	DLD1	viability	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.04689447850123851	[589]	[211,251,120]	0	hSpCas9	negative selection	796363
17836790	17836813	17	-	26627737	DLD1	viability	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	0.07758746116004461	[627]	[154,273,196]	0	hSpCas9	negative selection	796365
17819210	17819233	17	+	26627737	GBM cells	viability after 5 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.1490512867050377	[205]	[138,105]	2	hSpCas9	negative selection	878674
17819338	17819361	17	+	26627737	GBM cells	viability after 5 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	0.0860838227619306	[461]	[268,256]	1	hSpCas9	negative selection	878675
17819638	17819661	17	+	26627737	GBM cells	viability after 5 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-0.09546157592043629	[255]	[123,132]	-1	hSpCas9	negative selection	878676
17820280	17820303	17	+	26627737	GBM cells	viability after 5 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.0834742226963947	[424]	[212,269]	1	hSpCas9	negative selection	878677
17823591	17823614	17	-	26627737	GBM cells	viability after 5 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	-0.028573625329946423	[290]	[152,152]	0	hSpCas9	negative selection	878678
17836790	17836813	17	-	26627737	GBM cells	viability after 5 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-0.6330997458865117	[213]	[57,89]	-7	hSpCas9	negative selection	878680
17819210	17819233	17	+	26627737	GBM cells	viability after 13 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	-0.09774903377820704	[205]	[104,103]	-1	hSpCas9	negative selection	960989
17819338	17819361	17	+	26627737	GBM cells	viability after 13 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	0.05886960810079411	[461]	[350,187]	0	hSpCas9	negative selection	960990
17819638	17819661	17	+	26627737	GBM cells	viability after 13 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	0.015396466823612856	[255]	[162,121]	0	hSpCas9	negative selection	960991
17820280	17820303	17	+	26627737	GBM cells	viability after 13 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	-0.24395428623491455	[424]	[186,200]	-3	hSpCas9	negative selection	960992
17823591	17823614	17	-	26627737	GBM cells	viability after 13 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.07985180724508012	[290]	[194,143]	1	hSpCas9	negative selection	960993
17836790	17836813	17	-	26627737	GBM cells	viability after 13 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-0.839119221687215	[213]	[81,50]	-7	hSpCas9	negative selection	960995
17819210	17819233	17	+	26627737	GBM cells	viability after 21 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	-0.08836236731584157	[205]	[98,110]	-1	hSpCas9	negative selection	1043304
17819338	17819361	17	+	26627737	GBM cells	viability after 21 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-0.14857319856055418	[461]	[227,224]	-1	hSpCas9	negative selection	1043305
17819638	17819661	17	+	26627737	GBM cells	viability after 21 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	0.009516316560624787	[255]	[139,139]	0	hSpCas9	negative selection	1043306
17820280	17820303	17	+	26627737	GBM cells	viability after 21 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.20293062674779172	[424]	[282,249]	2	hSpCas9	negative selection	1043307
17823591	17823614	17	-	26627737	GBM cells	viability after 21 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.12078369129807326	[290]	[185,158]	1	hSpCas9	negative selection	1043308
17836790	17836813	17	-	26627737	GBM cells	viability after 21 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-1.2315532657751316	[213]	[60,38]	-7	hSpCas9	negative selection	1043310
17819210	17819233	17	+	26627737	RPE1	viability after 9 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.015167187186971187	[416]	[158,96]	0	hSpCas9	negative selection	1125619
17819338	17819361	17	+	26627737	RPE1	viability after 9 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	1.6225221147361417	[783]	[450,1148]	8	hSpCas9	negative selection	1125620
17819638	17819661	17	+	26627737	RPE1	viability after 9 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-1.1515958675843012	[1299]	[125,256]	-7	hSpCas9	negative selection	1125621
17820280	17820303	17	+	26627737	RPE1	viability after 9 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.36771428275611867	[1011]	[403,414]	2	hSpCas9	negative selection	1125622
17823591	17823614	17	-	26627737	RPE1	viability after 9 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.6847396678398956	[1019]	[380,683]	4	hSpCas9	negative selection	1125623
17836790	17836813	17	-	26627737	RPE1	viability after 9 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	1.4352708636906075	[456]	[406,360]	7	hSpCas9	negative selection	1125625
17819210	17819233	17	+	26627737	RPE1	viability after 12 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.848785927043108	[416]	[295,101]	5	hSpCas9	negative selection	1207934
17819338	17819361	17	+	26627737	RPE1	viability after 12 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	1.4539719455876534	[783]	[493,664]	7	hSpCas9	negative selection	1207935
17819638	17819661	17	+	26627737	RPE1	viability after 12 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-1.231785065000866	[1299]	[138,158]	-7	hSpCas9	negative selection	1207936
17820280	17820303	17	+	26627737	RPE1	viability after 12 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.4219312896776301	[1011]	[440,282]	3	hSpCas9	negative selection	1207937
17823591	17823614	17	-	26627737	RPE1	viability after 12 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.46781201298537145	[1019]	[259,504]	3	hSpCas9	negative selection	1207938
17836790	17836813	17	-	26627737	RPE1	viability after 12 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	1.81217882794962	[456]	[538,316]	8	hSpCas9	negative selection	1207940
17819210	17819233	17	+	26627737	RPE1	viability after 15 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	1.1353213595859297	[416]	[392,129]	6	hSpCas9	negative selection	1290249
17819338	17819361	17	+	26627737	RPE1	viability after 15 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	1.5114084201968556	[783]	[448,808]	7	hSpCas9	negative selection	1290250
17819638	17819661	17	+	26627737	RPE1	viability after 15 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-1.1083640419461802	[1299]	[194,146]	-6	hSpCas9	negative selection	1290251
17820280	17820303	17	+	26627737	RPE1	viability after 15 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	-0.05575091812590516	[1011]	[307,243]	0	hSpCas9	negative selection	1290252
17823591	17823614	17	-	26627737	RPE1	viability after 15 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.8107437524307866	[1019]	[245,756]	5	hSpCas9	negative selection	1290253
17836790	17836813	17	-	26627737	RPE1	viability after 15 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	1.9738498130540678	[456]	[658,361]	8	hSpCas9	negative selection	1290255
17819210	17819233	17	+	26627737	RPE1	viability after 18 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.8187082147333338	[416]	[343,42]	5	hSpCas9	negative selection	1372564
17819338	17819361	17	+	26627737	RPE1	viability after 18 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	1.8719694884360671	[783]	[524,1040]	8	hSpCas9	negative selection	1372565
17819638	17819661	17	+	26627737	RPE1	viability after 18 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-1.5508742770169444	[1299]	[82,158]	-7	hSpCas9	negative selection	1372566
17820280	17820303	17	+	26627737	RPE1	viability after 18 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.5290908897111117	[1011]	[396,390]	3	hSpCas9	negative selection	1372567
17823591	17823614	17	-	26627737	RPE1	viability after 18 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.9374020608281848	[1019]	[283,786]	5	hSpCas9	negative selection	1372568
17836790	17836813	17	-	26627737	RPE1	viability after 18 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	1.5145444339293692	[456]	[464,231]	7	hSpCas9	negative selection	1372570
17819210	17819233	17	+	26627737	HeLa	viability after 8 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.7900072961359692	[136]	[58,99,137]	6	hSpCas9	negative selection	1454879
17819338	17819361	17	+	26627737	HeLa	viability after 8 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-1.1000813215019916	[585]	[173,120,76]	-8	hSpCas9	negative selection	1454880
17819638	17819661	17	+	26627737	HeLa	viability after 8 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-0.2545607510778683	[503]	[200,195,159]	-2	hSpCas9	negative selection	1454881
17820280	17820303	17	+	26627737	HeLa	viability after 8 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.31799575045901607	[765]	[537,386,352]	3	hSpCas9	negative selection	1454882
17823591	17823614	17	-	26627737	HeLa	viability after 8 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.4086867158450751	[423]	[154,374,188]	4	hSpCas9	negative selection	1454883
17836790	17836813	17	-	26627737	HeLa	viability after 8 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-0.16805132730361666	[580]	[235,342,106]	-1	hSpCas9	negative selection	1454885
17819210	17819233	17	+	26627737	HeLa	viability after 12 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	1.4893254006179824	[136]	[116,183,171]	8	hSpCas9	negative selection	1537194
17819338	17819361	17	+	26627737	HeLa	viability after 12 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	0.32457778420282113	[585]	[317,248,348]	3	hSpCas9	negative selection	1537195
17819638	17819661	17	+	26627737	HeLa	viability after 12 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-0.006344203446103203	[503]	[173,170,279]	0	hSpCas9	negative selection	1537196
17820280	17820303	17	+	26627737	HeLa	viability after 12 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.13171032308816044	[765]	[368,328,344]	1	hSpCas9	negative selection	1537197
17823591	17823614	17	-	26627737	HeLa	viability after 12 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.8052624497761742	[423]	[435,186,311]	6	hSpCas9	negative selection	1537198
17836790	17836813	17	-	26627737	HeLa	viability after 12 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-0.575931243366681	[580]	[130,154,196]	-5	hSpCas9	negative selection	1537200
17819210	17819233	17	+	26627737	HeLa	viability after 15 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	1.7943498747645434	[136]	[227,241,102]	9	hSpCas9	negative selection	1619509
17819338	17819361	17	+	26627737	HeLa	viability after 15 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	0.6504628619279751	[585]	[487,161,479]	5	hSpCas9	negative selection	1619510
17819638	17819661	17	+	26627737	HeLa	viability after 15 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	0.3399455205772061	[503]	[235,203,345]	3	hSpCas9	negative selection	1619511
17820280	17820303	17	+	26627737	HeLa	viability after 15 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.08546891679732593	[765]	[283,211,510]	0	hSpCas9	negative selection	1619512
17823591	17823614	17	-	26627737	HeLa	viability after 15 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	-0.24744810170461568	[423]	[100,54,291]	-2	hSpCas9	negative selection	1619513
17836790	17836813	17	-	26627737	HeLa	viability after 15 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-1.501070448406975	[580]	[82,7,165]	-8	hSpCas9	negative selection	1619515
17819210	17819233	17	+	26627737	HeLa	viability after 18 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	1.828125472437175	[136]	[166,193,102]	9	hSpCas9	negative selection	1701824
17819338	17819361	17	+	26627737	HeLa	viability after 18 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	0.6721957963110397	[585]	[332,140,479]	5	hSpCas9	negative selection	1701825
17819638	17819661	17	+	26627737	HeLa	viability after 18 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	0.3207342492077621	[503]	[149,170,345]	2	hSpCas9	negative selection	1701826
17820280	17820303	17	+	26627737	HeLa	viability after 18 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.07695272907314066	[765]	[199,158,510]	0	hSpCas9	negative selection	1701827
17823591	17823614	17	-	26627737	HeLa	viability after 18 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	-0.2454136124885889	[423]	[66,46,291]	-2	hSpCas9	negative selection	1701828
17836790	17836813	17	-	26627737	HeLa	viability after 18 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-1.4974331711775801	[580]	[54,7,165]	-8	hSpCas9	negative selection	1701830
17819210	17819233	17	+	26627737	HCT116	viability after 6 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.6064134793316103	[348]	[98,74]	3	hSpCas9	negative selection	1784139
17819338	17819361	17	+	26627737	HCT116	viability after 6 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-0.7050936818581174	[1071]	[123,91]	-4	hSpCas9	negative selection	1784140
17819638	17819661	17	+	26627737	HCT116	viability after 6 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-0.3533490411049548	[1252]	[81,193]	-2	hSpCas9	negative selection	1784141
17820280	17820303	17	+	26627737	HCT116	viability after 6 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.6054544047211663	[1493]	[172,458]	3	hSpCas9	negative selection	1784142
17823591	17823614	17	-	26627737	HCT116	viability after 6 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	-0.05333716847441988	[842]	[99,142]	0	hSpCas9	negative selection	1784143
17836790	17836813	17	-	26627737	HCT116	viability after 6 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-0.5727129061159498	[796]	[100,74]	-3	hSpCas9	negative selection	1784145
17819210	17819233	17	+	26627737	HCT116	viability after 8 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.10217285312652025	[222]	[194,84,116]	1	hSpCas9	negative selection	1866454
17819338	17819361	17	+	26627737	HCT116	viability after 8 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	0.12030477218498581	[552]	[520,223,252]	1	hSpCas9	negative selection	1866455
17819638	17819661	17	+	26627737	HCT116	viability after 8 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-0.3191252250605589	[469]	[199,162,258]	-4	hSpCas9	negative selection	1866456
17820280	17820303	17	+	26627737	HCT116	viability after 8 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.011831406483830076	[693]	[316,414,422]	0	hSpCas9	negative selection	1866457
17823591	17823614	17	-	26627737	HCT116	viability after 8 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.6603575927428561	[205]	[258,131,148]	6	hSpCas9	negative selection	1866458
17836790	17836813	17	-	26627737	HCT116	viability after 8 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	0.06664372221283033	[324]	[203,175,182]	0	hSpCas9	negative selection	1866460
17819210	17819233	17	+	26627737	HCT116	viability after 9 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.2519711316234685	[348]	[115,106]	2	hSpCas9	negative selection	1948769
17819338	17819361	17	+	26627737	HCT116	viability after 9 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-0.7897445940706485	[1071]	[140,184]	-5	hSpCas9	negative selection	1948770
17819638	17819661	17	+	26627737	HCT116	viability after 9 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-0.5538610413962944	[1252]	[285,181]	-4	hSpCas9	negative selection	1948771
17820280	17820303	17	+	26627737	HCT116	viability after 9 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	-1.364772896820312	[1493]	[193,123]	-7	hSpCas9	negative selection	1948772
17823591	17823614	17	-	26627737	HCT116	viability after 9 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.5645109119745506	[842]	[538,169]	4	hSpCas9	negative selection	1948773
17836790	17836813	17	-	26627737	HCT116	viability after 9 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-0.9212254254075831	[796]	[103,118]	-6	hSpCas9	negative selection	1948775
17819210	17819233	17	+	26627737	HCT116	viability after 12 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.9775708035947767	[222]	[344,136,197]	8	hSpCas9	negative selection	2031084
17819338	17819361	17	+	26627737	HCT116	viability after 12 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-0.010909776421563433	[552]	[408,259,184]	0	hSpCas9	negative selection	2031085
17819638	17819661	17	+	26627737	HCT116	viability after 12 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-0.25031555001576394	[469]	[357,93,154]	-3	hSpCas9	negative selection	2031086
17820280	17820303	17	+	26627737	HCT116	viability after 12 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	-0.08092362601310299	[693]	[280,341,416]	-1	hSpCas9	negative selection	2031087
17823591	17823614	17	-	26627737	HCT116	viability after 12 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	1.1419925334765817	[205]	[181,249,289]	8	hSpCas9	negative selection	2031088
17836790	17836813	17	-	26627737	HCT116	viability after 12 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	0.5943482085312891	[324]	[349,236,177]	5	hSpCas9	negative selection	2031090
17819210	17819233	17	+	26627737	HCT116	viability after 15 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.5618066503537356	[222]	[243,155,173]	5	hSpCas9	negative selection	2113399
17819338	17819361	17	+	26627737	HCT116	viability after 15 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	0.41964902963374395	[552]	[620,228,447]	4	hSpCas9	negative selection	2113400
17819638	17819661	17	+	26627737	HCT116	viability after 15 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-0.10764666556249636	[469]	[261,162,326]	-1	hSpCas9	negative selection	2113401
17820280	17820303	17	+	26627737	HCT116	viability after 15 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	-0.3011505481659076	[693]	[382,298,295]	-3	hSpCas9	negative selection	2113402
17823591	17823614	17	-	26627737	HCT116	viability after 15 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.8089225149827934	[205]	[264,172,190]	7	hSpCas9	negative selection	2113403
17836790	17836813	17	-	26627737	HCT116	viability after 15 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	0.5525555169046595	[324]	[307,208,307]	5	hSpCas9	negative selection	2113405
17819210	17819233	17	+	26627737	HCT116	viability after 18 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	1.098926181730775	[222]	[325,129,243]	8	hSpCas9	negative selection	2195714
17819338	17819361	17	+	26627737	HCT116	viability after 18 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	0.3604431584134712	[552]	[432,277,321]	3	hSpCas9	negative selection	2195715
17819638	17819661	17	+	26627737	HCT116	viability after 18 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	0.27065995719088976	[469]	[343,273,200]	2	hSpCas9	negative selection	2195716
17820280	17820303	17	+	26627737	HCT116	viability after 18 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	-0.5309223870677796	[693]	[212,159,332]	-5	hSpCas9	negative selection	2195717
17823591	17823614	17	-	26627737	HCT116	viability after 18 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.8739766423034772	[205]	[104,261,174]	7	hSpCas9	negative selection	2195718
17836790	17836813	17	-	26627737	HCT116	viability after 18 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	0.42046870403014336	[324]	[285,177,166]	3	hSpCas9	negative selection	2195720
17820477	17820500	17	+	24336569	HL60	viability	GGCCAGGGAAGTCACTGTCTTGG	SREBF1	ENSG00000072310	-1.2927783900153624	[799]	[690]	-8	hSpCas9	negative selection	2297233
17836716	17836739	17	+	24336569	HL60	viability	CCCTGACGCACCTTCGATGTCGG	SREBF1	ENSG00000072310	-0.48209348763069676	[630]	[955]	-4	hSpCas9	negative selection	2297234
17836726	17836749	17	-	24336569	HL60	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.0728060188125299	[1080]	[2405]	0	hSpCas9	negative selection	2297235
17836744	17836767	17	+	24336569	HL60	viability	AGCGCCGCGTCCAGATCGCACGG	SREBF1	ENSG00000072310	-0.33672115587097073	[665]	[1115]	-3	hSpCas9	negative selection	2297236
17836754	17836777	17	-	24336569	HL60	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.21769987821562967	[454]	[827]	-2	hSpCas9	negative selection	2297237
17836771	17836794	17	-	24336569	HL60	viability	GCGGCTTTGGAGCAGGCGCTGGG	SREBF1	ENSG00000072310	-0.07229245473064594	[391]	[788]	0	hSpCas9	negative selection	2297238
17836778	17836801	17	-	24336569	HL60	viability	CAGCGAGGCGGCTTTGGAGCAGG	SREBF1	ENSG00000072310	-0.5181756427661101	[692]	[1023]	-5	hSpCas9	negative selection	2297239
17836783	17836806	17	+	24336569	HL60	viability	TCCAAAGCCGCCTCGCTGAAGGG	SREBF1	ENSG00000072310	0.22680344467475044	[190]	[472]	2	hSpCas9	negative selection	2297240
17836790	17836813	17	-	24336569	HL60	viability	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-0.07700445243819642	[968]	[1943]	0	hSpCas9	negative selection	2297241
17836797	17836820	17	+	24336569	HL60	viability	GCTGAAGGGTGGCTCGTCCATGG	SREBF1	ENSG00000072310	0.053847802247548066	[538]	[1183]	0	hSpCas9	negative selection	2297242
17820477	17820500	17	+	24336569	KBM7	viability	GGCCAGGGAAGTCACTGTCTTGG	SREBF1	ENSG00000072310	0.4313913136021993	[319]	[1176]	4	hSpCas9	negative selection	2364410
17836716	17836739	17	+	24336569	KBM7	viability	CCCTGACGCACCTTCGATGTCGG	SREBF1	ENSG00000072310	0.6502490535470733	[309]	[1326]	6	hSpCas9	negative selection	2364411
17836726	17836749	17	-	24336569	KBM7	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-0.44666523070210407	[788]	[1578]	-4	hSpCas9	negative selection	2364412
17836744	17836767	17	+	24336569	KBM7	viability	AGCGCCGCGTCCAGATCGCACGG	SREBF1	ENSG00000072310	0.5971486096483173	[261]	[1080]	5	hSpCas9	negative selection	2364413
17836754	17836777	17	-	24336569	KBM7	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.2691896960383443	[641]	[1452]	-2	hSpCas9	negative selection	2364414
17836771	17836794	17	-	24336569	KBM7	viability	GCGGCTTTGGAGCAGGCGCTGGG	SREBF1	ENSG00000072310	-0.2125338872687622	[372]	[877]	-2	hSpCas9	negative selection	2364415
17836778	17836801	17	-	24336569	KBM7	viability	CAGCGAGGCGGCTTTGGAGCAGG	SREBF1	ENSG00000072310	0.17133063609561125	[363]	[1117]	1	hSpCas9	negative selection	2364416
17836783	17836806	17	+	24336569	KBM7	viability	TCCAAAGCCGCCTCGCTGAAGGG	SREBF1	ENSG00000072310	-0.0038626212634778057	[192]	[524]	0	hSpCas9	negative selection	2364417
17836790	17836813	17	-	24336569	KBM7	viability	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-1.6470232849112498	[394]	[343]	-8	hSpCas9	negative selection	2364418
17836797	17836820	17	+	24336569	KBM7	viability	GCTGAAGGGTGGCTCGTCCATGG	SREBF1	ENSG00000072310	-1.4772585412135892	[441]	[432]	-7	hSpCas9	negative selection	2364419
17829847	17829870	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGGCTGGTCTTGAACTCCCAG	SREBF1	ENSG00000072310	1.1112377139242877	[89,193]	[7,132]	4	dCas9-VP64	positive selection	2451647
17829847	17829870	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGGCTGGTCTTGAACTCCCAG	SREBF1	ENSG00000072310	-0.05379639634842043	[67,143]	[20,43]	0	dCas9-VP64	positive selection	2546902
17836726	17836749	17	-	27260157	DLD1	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.323354927794352	[]	[]	4	hSpCas9	negative selection	2574249
17819557	17819580	17	+	27260157	DLD1	viability	GAGGTCACAGTGGTCGTTACAGG	SREBF1	ENSG00000072310	0.278135217888372	[]	[]	4	hSpCas9	negative selection	2577580
17836771	17836794	17	-	27260157	DLD1	viability	GCGGCTTTGGAGCAGGCGCTGGG	SREBF1	ENSG00000072310	0.0421165149051375	[]	[]	0	hSpCas9	negative selection	2580043
17836783	17836806	17	+	27260157	DLD1	viability	TCCAAAGCCGCCTCGCTGAAGGG	SREBF1	ENSG00000072310	-0.55471608990978	[]	[]	-4	hSpCas9	negative selection	2581430
17823533	17823556	17	-	27260157	DLD1	viability	GGGCGCAGATCGCGGAGCCATGG	SREBF1	ENSG00000072310	1.01863146859145	[]	[]	9	hSpCas9	negative selection	2584562
17836784	17836807	17	-	27260157	DLD1	viability	ACCCTTCAGCGAGGCGGCTTTGG	SREBF1	ENSG00000072310	0.414001855520456	[]	[]	4	hSpCas9	negative selection	2585026
17836716	17836739	17	+	27260157	DLD1	viability	CCCTGACGCACCTTCGATGTCGG	SREBF1	ENSG00000072310	0.0580926851585653	[]	[]	3	hSpCas9	negative selection	2587641
17836744	17836767	17	+	27260157	DLD1	viability	AGCGCCGCGTCCAGATCGCACGG	SREBF1	ENSG00000072310	-1.24328384815655	[]	[]	-7	hSpCas9	negative selection	2605782
17819207	17819230	17	-	27260157	DLD1	viability	GGTGAGTGGCGGAACCATCTTGG	SREBF1	ENSG00000072310	0.104513406411739	[]	[]	3	hSpCas9	negative selection	2606634
17820275	17820298	17	+	27260157	DLD1	viability	ATGGACGGGTACATCTTCAATGG	SREBF1	ENSG00000072310	0.139630762941576	[]	[]	3	hSpCas9	negative selection	2607770
17820339	17820362	17	-	27260157	DLD1	viability	AGCCTTCCTGAGCGGGCCGCAGG	SREBF1	ENSG00000072310	-1.14577150100222	[]	[]	-7	hSpCas9	negative selection	2608272
17836790	17836813	17	-	27260157	DLD1	viability	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-0.444600327093926	[]	[]	-4	hSpCas9	negative selection	2616313
17820337	17820360	17	+	27260157	DLD1	viability	TGCCTGCGGCCCGCTCAGGAAGG	SREBF1	ENSG00000072310	0.286552054713149	[]	[]	4	hSpCas9	negative selection	2617514
17836754	17836777	17	-	27260157	DLD1	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-1.06975298055621	[]	[]	-7	hSpCas9	negative selection	2624255
17836778	17836801	17	-	27260157	DLD1	viability	CAGCGAGGCGGCTTTGGAGCAGG	SREBF1	ENSG00000072310	-0.3742847127345	[]	[]	-3	hSpCas9	negative selection	2641872
17820477	17820500	17	+	27260157	DLD1	viability	GGCCAGGGAAGTCACTGTCTTGG	SREBF1	ENSG00000072310	-1.34120907139108	[]	[]	-8	hSpCas9	negative selection	2644103
17823591	17823614	17	-	27260157	DLD1	viability	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	-0.736553761999387	[]	[]	-5	hSpCas9	negative selection	2645066
17823542	17823565	17	+	27260157	DLD1	viability	CGCGATCTGCGCCCGCCCTTGGG	SREBF1	ENSG00000072310	-0.960581700189683	[]	[]	-7	hSpCas9	negative selection	2645093
17836797	17836820	17	+	27260157	DLD1	viability	GCTGAAGGGTGGCTCGTCCATGG	SREBF1	ENSG00000072310	-0.334954863983083	[]	[]	-3	hSpCas9	negative selection	2648662
17836726	17836749	17	-	27260157	HT1080	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.535335821495311	[]	[]	5	hSpCas9	negative selection	2650379
17819557	17819580	17	+	27260157	HT1080	viability	GAGGTCACAGTGGTCGTTACAGG	SREBF1	ENSG00000072310	-0.480465238667255	[]	[]	-7	hSpCas9	negative selection	2653710
17836771	17836794	17	-	27260157	HT1080	viability	GCGGCTTTGGAGCAGGCGCTGGG	SREBF1	ENSG00000072310	-0.958819942898579	[]	[]	-8	hSpCas9	negative selection	2656173
17836783	17836806	17	+	27260157	HT1080	viability	TCCAAAGCCGCCTCGCTGAAGGG	SREBF1	ENSG00000072310	-0.859836170284664	[]	[]	-8	hSpCas9	negative selection	2657560
17823533	17823556	17	-	27260157	HT1080	viability	GGGCGCAGATCGCGGAGCCATGG	SREBF1	ENSG00000072310	-0.0855495025277487	[]	[]	0	hSpCas9	negative selection	2660692
17836784	17836807	17	-	27260157	HT1080	viability	ACCCTTCAGCGAGGCGGCTTTGG	SREBF1	ENSG00000072310	0.363897783362705	[]	[]	3	hSpCas9	negative selection	2661156
17836716	17836739	17	+	27260157	HT1080	viability	CCCTGACGCACCTTCGATGTCGG	SREBF1	ENSG00000072310	-1.07541289842947	[]	[]	-8	hSpCas9	negative selection	2663771
17836744	17836767	17	+	27260157	HT1080	viability	AGCGCCGCGTCCAGATCGCACGG	SREBF1	ENSG00000072310	-0.678701688621561	[]	[]	-8	hSpCas9	negative selection	2681912
17819207	17819230	17	-	27260157	HT1080	viability	GGTGAGTGGCGGAACCATCTTGG	SREBF1	ENSG00000072310	-0.426673890778815	[]	[]	-7	hSpCas9	negative selection	2682764
17820275	17820298	17	+	27260157	HT1080	viability	ATGGACGGGTACATCTTCAATGG	SREBF1	ENSG00000072310	0.290763269822964	[]	[]	2	hSpCas9	negative selection	2683900
17820339	17820362	17	-	27260157	HT1080	viability	AGCCTTCCTGAGCGGGCCGCAGG	SREBF1	ENSG00000072310	0.331678139580821	[]	[]	3	hSpCas9	negative selection	2684402
17836790	17836813	17	-	27260157	HT1080	viability	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-2.50463478542384	[]	[]	-9	hSpCas9	negative selection	2692443
17820337	17820360	17	+	27260157	HT1080	viability	TGCCTGCGGCCCGCTCAGGAAGG	SREBF1	ENSG00000072310	-0.427802390865752	[]	[]	-7	hSpCas9	negative selection	2693644
17836754	17836777	17	-	27260157	HT1080	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-1.12964413119989	[]	[]	-8	hSpCas9	negative selection	2700385
17836778	17836801	17	-	27260157	HT1080	viability	CAGCGAGGCGGCTTTGGAGCAGG	SREBF1	ENSG00000072310	-0.75775023739482	[]	[]	-8	hSpCas9	negative selection	2718002
17820477	17820500	17	+	27260157	HT1080	viability	GGCCAGGGAAGTCACTGTCTTGG	SREBF1	ENSG00000072310	-0.991500893149751	[]	[]	-8	hSpCas9	negative selection	2720233
17823591	17823614	17	-	27260157	HT1080	viability	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	-0.12977185668347	[]	[]	0	hSpCas9	negative selection	2721196
17823542	17823565	17	+	27260157	HT1080	viability	CGCGATCTGCGCCCGCCCTTGGG	SREBF1	ENSG00000072310	-0.595665047328257	[]	[]	-7	hSpCas9	negative selection	2721223
17836797	17836820	17	+	27260157	HT1080	viability	GCTGAAGGGTGGCTCGTCCATGG	SREBF1	ENSG00000072310	-1.33540814985171	[]	[]	-9	hSpCas9	negative selection	2724792
17836726	17836749	17	-	27260157	MKN45	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.825898411007287	[]	[]	8	hSpCas9	negative selection	2726509
17819557	17819580	17	+	27260157	MKN45	viability	GAGGTCACAGTGGTCGTTACAGG	SREBF1	ENSG00000072310	-0.784354441024143	[]	[]	-7	hSpCas9	negative selection	2729840
17836771	17836794	17	-	27260157	MKN45	viability	GCGGCTTTGGAGCAGGCGCTGGG	SREBF1	ENSG00000072310	0.681195065352844	[]	[]	7	hSpCas9	negative selection	2732303
17836783	17836806	17	+	27260157	MKN45	viability	TCCAAAGCCGCCTCGCTGAAGGG	SREBF1	ENSG00000072310	-0.236453442006986	[]	[]	-1	hSpCas9	negative selection	2733690
17823533	17823556	17	-	27260157	MKN45	viability	GGGCGCAGATCGCGGAGCCATGG	SREBF1	ENSG00000072310	-0.262608823625049	[]	[]	-1	hSpCas9	negative selection	2736822
17836784	17836807	17	-	27260157	MKN45	viability	ACCCTTCAGCGAGGCGGCTTTGG	SREBF1	ENSG00000072310	0.602976121317025	[]	[]	7	hSpCas9	negative selection	2737286
17836716	17836739	17	+	27260157	MKN45	viability	CCCTGACGCACCTTCGATGTCGG	SREBF1	ENSG00000072310	-0.224932918187681	[]	[]	-1	hSpCas9	negative selection	2739901
17836744	17836767	17	+	27260157	MKN45	viability	AGCGCCGCGTCCAGATCGCACGG	SREBF1	ENSG00000072310	-1.680269718323	[]	[]	-9	hSpCas9	negative selection	2758042
17819207	17819230	17	-	27260157	MKN45	viability	GGTGAGTGGCGGAACCATCTTGG	SREBF1	ENSG00000072310	-0.888307345974599	[]	[]	-7	hSpCas9	negative selection	2758894
17820275	17820298	17	+	27260157	MKN45	viability	ATGGACGGGTACATCTTCAATGG	SREBF1	ENSG00000072310	1.32343095029215	[]	[]	9	hSpCas9	negative selection	2760030
17820339	17820362	17	-	27260157	MKN45	viability	AGCCTTCCTGAGCGGGCCGCAGG	SREBF1	ENSG00000072310	0.872543226863666	[]	[]	8	hSpCas9	negative selection	2760532
17836790	17836813	17	-	27260157	MKN45	viability	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-0.634631506673578	[]	[]	-6	hSpCas9	negative selection	2768573
17820337	17820360	17	+	27260157	MKN45	viability	TGCCTGCGGCCCGCTCAGGAAGG	SREBF1	ENSG00000072310	0.457538710961465	[]	[]	6	hSpCas9	negative selection	2769774
17836754	17836777	17	-	27260157	MKN45	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.337871656797897	[]	[]	-1	hSpCas9	negative selection	2776515
17836778	17836801	17	-	27260157	MKN45	viability	CAGCGAGGCGGCTTTGGAGCAGG	SREBF1	ENSG00000072310	-0.404848569711804	[]	[]	-1	hSpCas9	negative selection	2794132
17820477	17820500	17	+	27260157	MKN45	viability	GGCCAGGGAAGTCACTGTCTTGG	SREBF1	ENSG00000072310	0.103634249204353	[]	[]	0	hSpCas9	negative selection	2796363
17823591	17823614	17	-	27260157	MKN45	viability	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	-0.918458043767195	[]	[]	-7	hSpCas9	negative selection	2797326
17823542	17823565	17	+	27260157	MKN45	viability	CGCGATCTGCGCCCGCCCTTGGG	SREBF1	ENSG00000072310	-0.829687630674462	[]	[]	-7	hSpCas9	negative selection	2797353
17836797	17836820	17	+	27260157	MKN45	viability	GCTGAAGGGTGGCTCGTCCATGG	SREBF1	ENSG00000072310	-1.15801473302175	[]	[]	-8	hSpCas9	negative selection	2800922
17836726	17836749	17	-	27260157	RKO	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.0994559264654489	[]	[]	0	hSpCas9	negative selection	2802639
17819557	17819580	17	+	27260157	RKO	viability	GAGGTCACAGTGGTCGTTACAGG	SREBF1	ENSG00000072310	0.364576698959955	[]	[]	2	hSpCas9	negative selection	2805970
17836771	17836794	17	-	27260157	RKO	viability	GCGGCTTTGGAGCAGGCGCTGGG	SREBF1	ENSG00000072310	-1.20444942793833	[]	[]	-8	hSpCas9	negative selection	2808433
17836783	17836806	17	+	27260157	RKO	viability	TCCAAAGCCGCCTCGCTGAAGGG	SREBF1	ENSG00000072310	-0.454528221718606	[]	[]	-6	hSpCas9	negative selection	2809820
17823533	17823556	17	-	27260157	RKO	viability	GGGCGCAGATCGCGGAGCCATGG	SREBF1	ENSG00000072310	1.0553824873633	[]	[]	9	hSpCas9	negative selection	2812952
17836784	17836807	17	-	27260157	RKO	viability	ACCCTTCAGCGAGGCGGCTTTGG	SREBF1	ENSG00000072310	0.223833618386711	[]	[]	1	hSpCas9	negative selection	2813416
17836716	17836739	17	+	27260157	RKO	viability	CCCTGACGCACCTTCGATGTCGG	SREBF1	ENSG00000072310	-0.853576325431684	[]	[]	-7	hSpCas9	negative selection	2816031
17836744	17836767	17	+	27260157	RKO	viability	AGCGCCGCGTCCAGATCGCACGG	SREBF1	ENSG00000072310	-2.63693522737244	[]	[]	-9	hSpCas9	negative selection	2834172
17819207	17819230	17	-	27260157	RKO	viability	GGTGAGTGGCGGAACCATCTTGG	SREBF1	ENSG00000072310	0.0754212799933304	[]	[]	0	hSpCas9	negative selection	2835024
17820275	17820298	17	+	27260157	RKO	viability	ATGGACGGGTACATCTTCAATGG	SREBF1	ENSG00000072310	0.591458018705693	[]	[]	3	hSpCas9	negative selection	2836160
17820339	17820362	17	-	27260157	RKO	viability	AGCCTTCCTGAGCGGGCCGCAGG	SREBF1	ENSG00000072310	-0.172573855524662	[]	[]	-1	hSpCas9	negative selection	2836662
17836790	17836813	17	-	27260157	RKO	viability	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-0.966297512024315	[]	[]	-8	hSpCas9	negative selection	2844703
17820337	17820360	17	+	27260157	RKO	viability	TGCCTGCGGCCCGCTCAGGAAGG	SREBF1	ENSG00000072310	-0.144511511664025	[]	[]	0	hSpCas9	negative selection	2845904
17836754	17836777	17	-	27260157	RKO	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-1.84772406554716	[]	[]	-9	hSpCas9	negative selection	2852645
17836778	17836801	17	-	27260157	RKO	viability	CAGCGAGGCGGCTTTGGAGCAGG	SREBF1	ENSG00000072310	-0.75493086873352	[]	[]	-7	hSpCas9	negative selection	2870262
17820477	17820500	17	+	27260157	RKO	viability	GGCCAGGGAAGTCACTGTCTTGG	SREBF1	ENSG00000072310	-1.44132557939714	[]	[]	-8	hSpCas9	negative selection	2872493
17823591	17823614	17	-	27260157	RKO	viability	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	-1.21786832055395	[]	[]	-8	hSpCas9	negative selection	2873456
17823542	17823565	17	+	27260157	RKO	viability	CGCGATCTGCGCCCGCCCTTGGG	SREBF1	ENSG00000072310	0.314651368976475	[]	[]	1	hSpCas9	negative selection	2873483
17836797	17836820	17	+	27260157	RKO	viability	GCTGAAGGGTGGCTCGTCCATGG	SREBF1	ENSG00000072310	-1.4349085993079	[]	[]	-8	hSpCas9	negative selection	2877052
17836726	17836749	17	-	27260157	SF268	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-1.40811459544295	[]	[]	-8	hSpCas9	negative selection	2878769
17819557	17819580	17	+	27260157	SF268	viability	GAGGTCACAGTGGTCGTTACAGG	SREBF1	ENSG00000072310	-2.07693366472571	[]	[]	-9	hSpCas9	negative selection	2882100
17836771	17836794	17	-	27260157	SF268	viability	GCGGCTTTGGAGCAGGCGCTGGG	SREBF1	ENSG00000072310	-0.516187026864286	[]	[]	-4	hSpCas9	negative selection	2884563
17836783	17836806	17	+	27260157	SF268	viability	TCCAAAGCCGCCTCGCTGAAGGG	SREBF1	ENSG00000072310	-1.52892489194989	[]	[]	-8	hSpCas9	negative selection	2885950
17823533	17823556	17	-	27260157	SF268	viability	GGGCGCAGATCGCGGAGCCATGG	SREBF1	ENSG00000072310	0.878413631395808	[]	[]	9	hSpCas9	negative selection	2889082
17836784	17836807	17	-	27260157	SF268	viability	ACCCTTCAGCGAGGCGGCTTTGG	SREBF1	ENSG00000072310	-0.332743301763431	[]	[]	-3	hSpCas9	negative selection	2889546
17836716	17836739	17	+	27260157	SF268	viability	CCCTGACGCACCTTCGATGTCGG	SREBF1	ENSG00000072310	-1.33078746710606	[]	[]	-7	hSpCas9	negative selection	2892161
17836744	17836767	17	+	27260157	SF268	viability	AGCGCCGCGTCCAGATCGCACGG	SREBF1	ENSG00000072310	-1.66689350038359	[]	[]	-8	hSpCas9	negative selection	2910302
17819207	17819230	17	-	27260157	SF268	viability	GGTGAGTGGCGGAACCATCTTGG	SREBF1	ENSG00000072310	-0.489354931066607	[]	[]	-4	hSpCas9	negative selection	2911154
17820275	17820298	17	+	27260157	SF268	viability	ATGGACGGGTACATCTTCAATGG	SREBF1	ENSG00000072310	-0.0155884423161701	[]	[]	0	hSpCas9	negative selection	2912290
17820339	17820362	17	-	27260157	SF268	viability	AGCCTTCCTGAGCGGGCCGCAGG	SREBF1	ENSG00000072310	-0.0117001572896527	[]	[]	0	hSpCas9	negative selection	2912792
17836790	17836813	17	-	27260157	SF268	viability	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-1.60538394910837	[]	[]	-8	hSpCas9	negative selection	2920833
17820337	17820360	17	+	27260157	SF268	viability	TGCCTGCGGCCCGCTCAGGAAGG	SREBF1	ENSG00000072310	-0.43143096267173	[]	[]	-3	hSpCas9	negative selection	2922034
17836754	17836777	17	-	27260157	SF268	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-1.05031343048757	[]	[]	-7	hSpCas9	negative selection	2928775
17836778	17836801	17	-	27260157	SF268	viability	CAGCGAGGCGGCTTTGGAGCAGG	SREBF1	ENSG00000072310	-1.04843135864687	[]	[]	-7	hSpCas9	negative selection	2946392
17820477	17820500	17	+	27260157	SF268	viability	GGCCAGGGAAGTCACTGTCTTGG	SREBF1	ENSG00000072310	-1.8183591985917	[]	[]	-8	hSpCas9	negative selection	2948623
17823591	17823614	17	-	27260157	SF268	viability	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	-0.0532731509886239	[]	[]	0	hSpCas9	negative selection	2949586
17823542	17823565	17	+	27260157	SF268	viability	CGCGATCTGCGCCCGCCCTTGGG	SREBF1	ENSG00000072310	-0.331810679634768	[]	[]	-3	hSpCas9	negative selection	2949613
17836797	17836820	17	+	27260157	SF268	viability	GCTGAAGGGTGGCTCGTCCATGG	SREBF1	ENSG00000072310	-1.34298921679645	[]	[]	-7	hSpCas9	negative selection	2953182
17820129	17820152	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGGGGTGGAGCTGAACTGCGG	SREBF1	ENSG00000072310	-0.35535726003550006	[4,4]	[3,1]	-5	hSpCas9	positive selection	3023674
17820113	17820136	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGGGTAGCCTAACACAGGGG	SREBF1	ENSG00000072310	-0.08534469099475134	[2,2]	[1,1]	-1	hSpCas9	positive selection	3023675
17817043	17817066	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGACAAAGAGAAGCACCAAGG	SREBF1	ENSG00000072310	-0.11632688915751849	[5,5]	[4,3]	-2	hSpCas9	positive selection	3023676
17820087	17820110	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACCTGTAGAGAAGCCTCCCGG	SREBF1	ENSG00000072310	-0.5420992990072163	[3,3]	[2,1]	-7	hSpCas9	positive selection	3023677
17820129	17820152	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGGGGTGGAGCTGAACTGCGG	SREBF1	ENSG00000072310	-0.5829393417684481	[4,4]	[3,0]	-7	hSpCas9	positive selection	3091532
17820113	17820136	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGGGTAGCCTAACACAGGGG	SREBF1	ENSG00000072310	-0.30773308119979814	[2,2]	[2,0]	-5	hSpCas9	positive selection	3091533
17817043	17817066	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGACAAAGAGAAGCACCAAGG	SREBF1	ENSG00000072310	-0.15731681058121305	[5,5]	[4,2]	-2	hSpCas9	positive selection	3091534
17820087	17820110	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACCTGTAGAGAAGCCTCCCGG	SREBF1	ENSG00000072310	0.010133864442690502	[3,3]	[2,2]	0	hSpCas9	positive selection	3091535
17817285	17817308		-	24336571	A375	resistance to PLX after 7 days	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.06340099003804411	[25,27]	[26,23]	-2	hSpCas9	positive selection	3147410
17836726	17836749		-	24336571	A375	resistance to PLX after 7 days	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-0.23346485747710066	[10,11]	[9,8]	-7	hSpCas9	positive selection	3147411
17836754	17836777		-	24336571	A375	resistance to PLX after 7 days	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.0053612158963572965	[22,22]	[24,20]	0	hSpCas9	positive selection	3147412
17817268	17817291		+	24336571	A375	resistance to PLX after 7 days	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.15844935768523782	[18,17]	[20,19]	5	hSpCas9	positive selection	3147413
17817285	17817308		-	24336571	A375	resistance to PLX after 14 days	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	0.09984513116292482	[24,26]	[14,9]	1	hSpCas9	positive selection	3205203
17836726	17836749		-	24336571	A375	resistance to PLX after 14 days	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-0.42320180914728545	[13,8]	[2,3]	-5	hSpCas9	positive selection	3205204
17836754	17836777		-	24336571	A375	resistance to PLX after 14 days	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	1.3067780268093783	[17,17]	[20,20]	8	hSpCas9	positive selection	3205205
17817268	17817291		+	24336571	A375	resistance to PLX after 14 days	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	1.8678283208307238	[14,15]	[24,26]	9	hSpCas9	positive selection	3205206
17817285	17817308		-	24336571	A375	viability after 7 days	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.15856029995535348	[31]	[25,27]	-2	hSpCas9	negative selection	3262996
17836726	17836749		-	24336571	A375	viability after 7 days	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.2731373173011055	[9]	[10,11]	4	hSpCas9	negative selection	3262997
17836754	17836777		-	24336571	A375	viability after 7 days	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.4482115303883493	[17]	[22,22]	6	hSpCas9	negative selection	3262998
17817268	17817291		+	24336571	A375	viability after 7 days	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.2597472591332844	[15]	[18,17]	4	hSpCas9	negative selection	3262999
17817285	17817308		-	24336571	A375	viability after 14 days	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.2058475167595898	[31]	[24,26]	-2	hSpCas9	negative selection	3320789
17836726	17836749		-	24336571	A375	viability after 14 days	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.2231534976149741	[9]	[13,8]	3	hSpCas9	negative selection	3320790
17836754	17836777		-	24336571	A375	viability after 14 days	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.13673087258094258	[17]	[17,17]	1	hSpCas9	negative selection	3320791
17817268	17817291		+	24336571	A375	viability after 14 days	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.012348368267682708	[15]	[14,15]	0	hSpCas9	negative selection	3320792
17817268	17817291	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.038157690983673484	[148,148]	[0,0]	0	hSpCas9	positive selection	3394918
17817285	17817308	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.6910410201388426	[246,246]	[0,0]	-5	hSpCas9	positive selection	3394919
17823541	17823564	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	2.935398116558473	[19,19]	[0,0]	8	hSpCas9	positive selection	3394920
17820128	17820151	17	+	26780180	HT29	viability (Avana library 4 designs)	ACAGGGGTGGAGCTGAACTGCGG	SREBF1	ENSG00000072310	2.71225682046216	[]	[]	8	hSpCas9	negative selection	3462343
17820112	17820135	17	+	26780180	HT29	viability (Avana library 4 designs)	GCTGGGGTAGCCTAACACAGGGG	SREBF1	ENSG00000072310	1.31684327140062	[]	[]	5	hSpCas9	negative selection	3462344
17817042	17817065	17	+	26780180	HT29	viability (Avana library 4 designs)	GTAGACAAAGAGAAGCACCAAGG	SREBF1	ENSG00000072310	1.62929536171565	[]	[]	6	hSpCas9	negative selection	3462345
17820086	17820109	17	+	26780180	HT29	viability (Avana library 4 designs)	TTACCTGTAGAGAAGCCTCCCGG	SREBF1	ENSG00000072310	2.78840734970517	[]	[]	8	hSpCas9	negative selection	3462346
17820112	17820135	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGGGTAGCCTAACACAGGGG	SREBF1	ENSG00000072310	-2.88704938302841	[]	[]	-3	hSpCas9	negative selection	3563850
17820086	17820109	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACCTGTAGAGAAGCCTCCCGG	SREBF1	ENSG00000072310	-2.92811571306043	[]	[]	-4	hSpCas9	negative selection	3563851
17817042	17817065	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGACAAAGAGAAGCACCAAGG	SREBF1	ENSG00000072310	-5.07218479166415	[]	[]	-5	hSpCas9	negative selection	3563852
17820128	17820151	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGGGGTGGAGCTGAACTGCGG	SREBF1	ENSG00000072310	-0.720120432098906	[]	[]	-1	hSpCas9	negative selection	3563853
17820462	17820485	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	-0.311271262845824	[]	[]	0	hSpCas9	negative selection	3563854
17819559	17819582	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCACAGTGGTCGTTACAGGGG	SREBF1	ENSG00000072310	1.74059701222215	[]	[]	2	hSpCas9	negative selection	3563855
17820112	17820135	17	+	26780180	A375	viability (Avana lentiGuide)	GCTGGGGTAGCCTAACACAGGGG	SREBF1	ENSG00000072310	2.03177411949989	[]	[]	2	hSpCas9	negative selection	3672509
17820086	17820109	17	+	26780180	A375	viability (Avana lentiGuide)	TTACCTGTAGAGAAGCCTCCCGG	SREBF1	ENSG00000072310	4.2691232509748	[]	[]	4	hSpCas9	negative selection	3672510
17817042	17817065	17	+	26780180	A375	viability (Avana lentiGuide)	GTAGACAAAGAGAAGCACCAAGG	SREBF1	ENSG00000072310	3.76977598033406	[]	[]	3	hSpCas9	negative selection	3672511
17820128	17820151	17	+	26780180	A375	viability (Avana lentiGuide)	ACAGGGGTGGAGCTGAACTGCGG	SREBF1	ENSG00000072310	21.5688825996388	[]	[]	9	hSpCas9	negative selection	3672512
17820462	17820485	17	+	26780180	A375	viability (Avana lentiGuide)	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	16.6574222253071	[]	[]	8	hSpCas9	negative selection	3672513
17819559	17819582	17	+	26780180	A375	viability (Avana lentiGuide)	GGTCACAGTGGTCGTTACAGGGG	SREBF1	ENSG00000072310	4.92037702276537	[]	[]	4	hSpCas9	negative selection	3672514
17820112	17820135	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGGGTAGCCTAACACAGGGG	SREBF1	ENSG00000072310	-0.19634918432655823	[4]	[3,3]	-3	hSpCas9	positive selection	3781116
17820086	17820109	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACCTGTAGAGAAGCCTCCCGG	SREBF1	ENSG00000072310	-0.1202161546197604	[5]	[4,4]	-2	hSpCas9	positive selection	3781117
17817042	17817065	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGACAAAGAGAAGCACCAAGG	SREBF1	ENSG00000072310	-0.19427044737886986	[6]	[6,5]	-3	hSpCas9	positive selection	3781118
17820128	17820151	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGGGGTGGAGCTGAACTGCGG	SREBF1	ENSG00000072310	0.10594182573484792	[5]	[6,6]	2	hSpCas9	positive selection	3781119
17820462	17820485	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	0.22346960381712017	[4]	[5,5]	6	hSpCas9	positive selection	3781120
17819559	17819582	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCACAGTGGTCGTTACAGGGG	SREBF1	ENSG00000072310	0.10258518609307621	[4]	[4,5]	2	hSpCas9	positive selection	3781121
17820112	17820135	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGGGTAGCCTAACACAGGGG	SREBF1	ENSG00000072310	-0.12065460651414764	[4]	[2,4]	-2	hSpCas9	positive selection	3889723
17820086	17820109	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACCTGTAGAGAAGCCTCCCGG	SREBF1	ENSG00000072310	-0.473040244277348	[6]	[3,3]	-6	hSpCas9	positive selection	3889724
17817042	17817065	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGACAAAGAGAAGCACCAAGG	SREBF1	ENSG00000072310	0.2074766940753624	[7]	[7,7]	5	hSpCas9	positive selection	3889725
17820128	17820151	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGGGGTGGAGCTGAACTGCGG	SREBF1	ENSG00000072310	-0.4966189310418775	[6]	[4,3]	-6	hSpCas9	positive selection	3889726
17820462	17820485	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	0.13588638588621568	[5]	[4,4]	3	hSpCas9	positive selection	3889727
17819559	17819582	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCACAGTGGTCGTTACAGGGG	SREBF1	ENSG00000072310	0.09140834150471987	[5]	[5,5]	2	hSpCas9	positive selection	3889728
17817285	17817308	17	-	26780180	A375	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	2.00338183537154	[]	[]	9	hSpCas9	negative selection	3999416
17823541	17823564	17	-	26780180	A375	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.848356165547329	[]	[]	3	hSpCas9	negative selection	3999417
17823517	17823540	17	-	26780180	A375	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.62401081397522	[]	[]	2	hSpCas9	negative selection	3999418
17836726	17836749	17	-	26780180	A375	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.235642138668121	[]	[]	0	hSpCas9	negative selection	3999419
17836754	17836777	17	-	26780180	A375	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.859901752098624	[]	[]	3	hSpCas9	negative selection	3999420
17817268	17817291	17	+	26780180	A375	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	1.39355413384578	[]	[]	7	hSpCas9	negative selection	3999421
17817285	17817308	17	-	26780180	HT29	viability (GeCKOv2 library)	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	2.40265455146705	[]	[]	9	hSpCas9	negative selection	4107382
17823541	17823564	17	-	26780180	HT29	viability (GeCKOv2 library)	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.771763735390136	[]	[]	3	hSpCas9	negative selection	4107383
17823517	17823540	17	-	26780180	HT29	viability (GeCKOv2 library)	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.808530994397969	[]	[]	3	hSpCas9	negative selection	4107384
17836726	17836749	17	-	26780180	HT29	viability (GeCKOv2 library)	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.445392728320437	[]	[]	1	hSpCas9	negative selection	4107385
17836754	17836777	17	-	26780180	HT29	viability (GeCKOv2 library)	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	1.74632223878594	[]	[]	8	hSpCas9	negative selection	4107386
17817268	17817291	17	+	26780180	HT29	viability (GeCKOv2 library)	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	1.45347306822784	[]	[]	7	hSpCas9	negative selection	4107387
17817285	17817308	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	0.06284320045529052	[4]	[3,3]	1	hSpCas9	positive selection	4173604
17836726	17836749	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-0.1997287570140884	[3]	[1,1]	-5	hSpCas9	positive selection	4173605
17836754	17836777	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.3533919638648088	[4]	[2,4]	8	hSpCas9	positive selection	4173606
17817268	17817291	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.241698825253437	[4]	[2,4]	6	hSpCas9	positive selection	4173607
17817285	17817308	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.17319317911653354	[4]	[0,2,4,0]	-2	hSpCas9	positive selection	4237626
17836726	17836749	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.4154909264230427	[4]	[5,6,1,0]	3	hSpCas9	positive selection	4237627
17836754	17836777	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.11033224555861879	[4]	[1,4,3,0]	0	hSpCas9	positive selection	4237628
17817268	17817291	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.2192580401188829	[5]	[0,3,3,0]	-3	hSpCas9	positive selection	4237629
17836726	17836749	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.7124227599360522	[0]	[1,0]	9	hSpCas9	positive selection	4300573
17836754	17836777	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.475940065727408	[2]	[1,0]	-8	hSpCas9	positive selection	4300574
17823517	17823540	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.6688694591632482	[3]	[3,5]	9	hSpCas9	positive selection	4300575
17817268	17817291	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.04136727128653679	[3]	[3,1]	0	hSpCas9	positive selection	4364828
17817285	17817308	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.3624799820423397	[3]	[3,0]	-6	hSpCas9	positive selection	4364829
17823541	17823564	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.3246058147912544	[1]	[0,0]	-6	hSpCas9	positive selection	4364830
17817397	17817419	17	-	27760321	OCIAML3	viability	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	0.2875349361132349	[1550,1297]	[1382,1316]	3	hSpCas9	negative selection	4443122
17818325	17818347	17	+	27760321	OCIAML3	viability	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	0.023833863964320523	[358,279]	[273,223]	0	hSpCas9	negative selection	4443123
17819149	17819171	17	-	27760321	OCIAML3	viability	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-0.05459186136009886	[665,572]	[406,540]	0	hSpCas9	negative selection	4443124
17819307	17819329	17	+	27760321	OCIAML3	viability	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	0.598811307499763	[829,687]	[756,1074]	7	hSpCas9	negative selection	4443125
17819570	17819592	17	+	27760321	OCIAML3	viability	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	0.17652768784359907	[991,916]	[663,1077]	2	hSpCas9	negative selection	4443126
17817397	17817419	17	-	27760321	OCIAML2	viability	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	0.05639048517144696	[1550,1297]	[1057,1371]	0	hSpCas9	negative selection	4526585
17818325	17818347	17	+	27760321	OCIAML2	viability	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	0.5300393103682174	[358,279]	[358,385]	7	hSpCas9	negative selection	4526586
17819149	17819171	17	-	27760321	OCIAML2	viability	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-0.34522321986962057	[665,572]	[360,435]	-4	hSpCas9	negative selection	4526587
17819307	17819329	17	+	27760321	OCIAML2	viability	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	0.36682110032744175	[829,687]	[663,951]	5	hSpCas9	negative selection	4526588
17819570	17819592	17	+	27760321	OCIAML2	viability	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-0.1049168272632699	[991,916]	[670,779]	-1	hSpCas9	negative selection	4526589
17817397	17817419	17	-	27760321	MV411	viability	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	-0.11317223828331135	[1550,1297]	[413,1543]	-1	hSpCas9	negative selection	4610048
17818325	17818347	17	+	27760321	MV411	viability	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	-2.381206311049575	[358,279]	[30,53]	-8	hSpCas9	negative selection	4610049
17819149	17819171	17	-	27760321	MV411	viability	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-0.30428048017745934	[665,572]	[232,475]	-2	hSpCas9	negative selection	4610050
17819307	17819329	17	+	27760321	MV411	viability	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	-0.5079872555610931	[829,687]	[183,600]	-4	hSpCas9	negative selection	4610051
17819570	17819592	17	+	27760321	MV411	viability	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-1.5368063728372197	[991,916]	[93,401]	-7	hSpCas9	negative selection	4610052
17817397	17817419	17	-	27760321	HL60	viability	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	0.9624613233547434	[1550,1297]	[1907,2629]	8	hSpCas9	negative selection	4693511
17818325	17818347	17	+	27760321	HL60	viability	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	-1.3970086339377827	[358,279]	[128,65]	-8	hSpCas9	negative selection	4693512
17819149	17819171	17	-	27760321	HL60	viability	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-0.23414685989996942	[665,572]	[511,340]	-3	hSpCas9	negative selection	4693513
17819307	17819329	17	+	27760321	HL60	viability	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	-0.35893435415161673	[829,687]	[491,469]	-4	hSpCas9	negative selection	4693514
17819570	17819592	17	+	27760321	HL60	viability	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-0.8430615507639627	[991,916]	[390,480]	-7	hSpCas9	negative selection	4693515
17817397	17817419	17	-	27760321	HT1080	viability	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	-2.70767833293091	[1297,1012]	[16,128]	-7	hSpCas9	negative selection	4776974
17818325	17818347	17	+	27760321	HT1080	viability	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	-1.7153694337424508	[279,218]	[35,23]	-6	hSpCas9	negative selection	4776975
17819149	17819171	17	-	27760321	HT1080	viability	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-0.4377436542537978	[572,446]	[191,103]	-2	hSpCas9	negative selection	4776976
17819307	17819329	17	+	27760321	HT1080	viability	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	-0.9493725101620215	[687,536]	[154,94]	-4	hSpCas9	negative selection	4776977
17819570	17819592	17	+	27760321	HT1080	viability	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-0.4707480482206563	[916,715]	[291,171]	-2	hSpCas9	negative selection	4776978
17817397	17817419	17	-	27760321	HT29	viability after 7 days	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	0.23147489013080746	[1297,1012]	[1709,1892,1625]	3	hSpCas9	negative selection	4860437
17818325	17818347	17	+	27760321	HT29	viability after 7 days	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	-0.31964772503280703	[279,218]	[231,269,264]	-4	hSpCas9	negative selection	4860438
17819149	17819171	17	-	27760321	HT29	viability after 7 days	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-0.40482131795940807	[572,446]	[540,626,328]	-5	hSpCas9	negative selection	4860439
17819307	17819329	17	+	27760321	HT29	viability after 7 days	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	0.3825974236601194	[687,536]	[1233,1290,596]	6	hSpCas9	negative selection	4860440
17819570	17819592	17	+	27760321	HT29	viability after 7 days	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-0.15474856177916574	[916,715]	[1077,762,1003]	-2	hSpCas9	negative selection	4860441
17817397	17817419	17	-	27760321	HT29	viability after 25 days	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	-0.7805877203827079	[1297,1012]	[751,914,623]	-6	hSpCas9	negative selection	4943900
17818325	17818347	17	+	27760321	HT29	viability after 25 days	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	-1.9029619891198548	[279,218]	[49,97,82]	-8	hSpCas9	negative selection	4943901
17819149	17819171	17	-	27760321	HT29	viability after 25 days	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-1.9310767447844142	[572,446]	[175,22,269]	-8	hSpCas9	negative selection	4943902
17819307	17819329	17	+	27760321	HT29	viability after 25 days	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	-0.9442467493060287	[687,536]	[281,397,421]	-6	hSpCas9	negative selection	4943903
17819570	17819592	17	+	27760321	HT29	viability after 25 days	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-0.3573780871738327	[916,715]	[779,601,806]	-4	hSpCas9	negative selection	4943904
17817397	17817419	17	-	27760321	HT29	viability after 22 days	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	-0.7968985358366137	[1297,1012]	[664,707,937]	-6	hSpCas9	negative selection	5027363
17818325	17818347	17	+	27760321	HT29	viability after 22 days	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	-1.649461554258127	[279,218]	[49,133,92]	-7	hSpCas9	negative selection	5027364
17819149	17819171	17	-	27760321	HT29	viability after 22 days	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-1.580875627994231	[572,446]	[181,174,234]	-7	hSpCas9	negative selection	5027365
17819307	17819329	17	+	27760321	HT29	viability after 22 days	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	-1.0572559519178444	[687,536]	[374,183,461]	-7	hSpCas9	negative selection	5027366
17819570	17819592	17	+	27760321	HT29	viability after 22 days	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-1.0095430903122242	[916,715]	[445,405,555]	-6	hSpCas9	negative selection	5027367
17817397	17817419	17	-	27760321	HT29	viability after 19 days	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	0.035265873906962675	[1297,1012]	[1238,1116,1680]	0	hSpCas9	negative selection	5110826
17818325	17818347	17	+	27760321	HT29	viability after 19 days	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	-1.7670606456089497	[279,218]	[192,41,29]	-8	hSpCas9	negative selection	5110827
17819149	17819171	17	-	27760321	HT29	viability after 19 days	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-1.7260802074258776	[572,446]	[149,37,331]	-7	hSpCas9	negative selection	5110828
17819307	17819329	17	+	27760321	HT29	viability after 19 days	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	-0.9519427803789222	[687,536]	[464,299,332]	-6	hSpCas9	negative selection	5110829
17819570	17819592	17	+	27760321	HT29	viability after 19 days	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-0.5842885469717496	[916,715]	[590,736,539]	-5	hSpCas9	negative selection	5110830
17817397	17817419	17	-	27760321	HT29	viability after 16 days	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	-0.22253743451207786	[1297,1012]	[1202,944,1188]	-3	hSpCas9	negative selection	5194289
17818325	17818347	17	+	27760321	HT29	viability after 16 days	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	-0.2782300746173828	[279,218]	[326,181,191]	-3	hSpCas9	negative selection	5194290
17819149	17819171	17	-	27760321	HT29	viability after 16 days	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-1.2133700850426217	[572,446]	[301,262,177]	-7	hSpCas9	negative selection	5194291
17819307	17819329	17	+	27760321	HT29	viability after 16 days	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	-0.12855484965749575	[687,536]	[670,573,640]	-1	hSpCas9	negative selection	5194292
17819570	17819592	17	+	27760321	HT29	viability after 16 days	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-0.6539798329240151	[916,715]	[724,513,517]	-6	hSpCas9	negative selection	5194293
17817397	17817419	17	-	27760321	HT29	viability after 13 days	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	0.13225285727049463	[1297,1012]	[2006,1218,1196]	1	hSpCas9	negative selection	5277752
17818325	17818347	17	+	27760321	HT29	viability after 13 days	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	-0.2664543558583963	[279,218]	[232,333,159]	-3	hSpCas9	negative selection	5277753
17819149	17819171	17	-	27760321	HT29	viability after 13 days	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-0.4637600725127506	[572,446]	[374,635,284]	-5	hSpCas9	negative selection	5277754
17819307	17819329	17	+	27760321	HT29	viability after 13 days	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	0.5600068060056348	[687,536]	[1027,1346,783]	7	hSpCas9	negative selection	5277755
17819570	17819592	17	+	27760321	HT29	viability after 13 days	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-0.747798778785681	[916,715]	[399,445,829]	-7	hSpCas9	negative selection	5277756
17817397	17817419	17	-	27760321	HT29	viability after 10 days	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	0.15349620786783524	[1297,1012]	[1379,1810,1627]	2	hSpCas9	negative selection	5361215
17818325	17818347	17	+	27760321	HT29	viability after 10 days	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	-0.40451909195090285	[279,218]	[218,300,188]	-5	hSpCas9	negative selection	5361216
17819149	17819171	17	-	27760321	HT29	viability after 10 days	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-0.9544388100963753	[572,446]	[204,509,276]	-7	hSpCas9	negative selection	5361217
17819307	17819329	17	+	27760321	HT29	viability after 10 days	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	0.2092457764450667	[687,536]	[725,1271,669]	2	hSpCas9	negative selection	5361218
17819570	17819592	17	+	27760321	HT29	viability after 10 days	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-0.15778311059318462	[916,715]	[1001,865,872]	-2	hSpCas9	negative selection	5361219
17817397	17817419	17	-	27760321	MOLM13	viability	ATGCTGGACCGCTCCCGCCTGG	SREBF1	ENSG00000072310	-1.2499071073703598	[1550,1297]	[200,451]	-6	hSpCas9	negative selection	5444678
17818325	17818347	17	+	27760321	MOLM13	viability	AGAAAGCGAATGTAGTCGATGG	SREBF1	ENSG00000072310	-2.3096551316584972	[358,279]	[0,65]	-8	hSpCas9	negative selection	5444679
17819149	17819171	17	-	27760321	MOLM13	viability	CTATCAACCGGCTCGCAGCTGG	SREBF1	ENSG00000072310	-2.03840600465098	[665,572]	[86,82]	-8	hSpCas9	negative selection	5444680
17819307	17819329	17	+	27760321	MOLM13	viability	CCACGTCACCCACCGGCAAAGG	SREBF1	ENSG00000072310	-3.0624190201092754	[829,687]	[63,39]	-9	hSpCas9	negative selection	5444681
17819570	17819592	17	+	27760321	MOLM13	viability	TCGTTACAGGGGCTGCCGTGGG	SREBF1	ENSG00000072310	-0.8854400739075847	[991,916]	[317,268]	-5	hSpCas9	negative selection	5444682
17823153	17823176	17	+	27661255	K562	viability	GCTGAATAGGGCAGACGCTGTGG	SREBF1	ENSG00000072310	0.40071386896275585	[417,599]	[508,553]	9	dCas9-KRAB	negative selection	5514249
17836552	17836575	17	+	27661255	K562	viability	GGAACCAGGGAGGCTCGGTGAGG	SREBF1	ENSG00000072310	0.04850195313580552	[419,616]	[446,406]	1	dCas9-KRAB	negative selection	5514250
17836632	17836655	17	+	27661255	K562	viability	GGCGCCCGTGGGGGAGACAAAGG	SREBF1	ENSG00000072310	-1.4002021469376436	[304,327]	[106,85]	-9	dCas9-KRAB	negative selection	5514251
17836857	17836880	17	+	27661255	K562	viability	GCCTCGTACGGCCCTTCCTAGGG	SREBF1	ENSG00000072310	0.07657137619456567	[528,423]	[443,367]	2	dCas9-KRAB	negative selection	5514252
17836959	17836982	17	+	27661255	K562	viability	GGCGCCGGCGAAAAGTTCCTCGG	SREBF1	ENSG00000072310	0.01933160441210413	[1019,1130]	[982,771]	0	dCas9-KRAB	negative selection	5514253
17823569	17823592	17	-	27661255	K562	viability	GAGGGGTAGGGCCAACGGCCTGG	SREBF1	ENSG00000072310	0.06832463222259058	[645,765]	[663,525]	2	dCas9-KRAB	negative selection	5514254
17823574	17823597	17	-	27661255	K562	viability	GCGGGGAGGGGTAGGGCCAACGG	SREBF1	ENSG00000072310	-0.12374447281821066	[430,453]	[423,238]	-4	dCas9-KRAB	negative selection	5514255
17823635	17823658	17	-	27661255	K562	viability	GGGCGCGCCGCAGCGCTCAACGG	SREBF1	ENSG00000072310	-0.03423618825508651	[1009,947]	[844,695]	-1	dCas9-KRAB	negative selection	5514256
17836912	17836935	17	-	27661255	K562	viability	GACACGAACGCGCGGAGCGGCGG	SREBF1	ENSG00000072310	-2.8300438434798876	[319,303]	[33,35]	-9	dCas9-KRAB	negative selection	5514257
17836726	17836749	17	-	27260156	BXPC3	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.3992163278154308	[37]	[59,41,54,51]	8	hSpCas9	negative selection	5573033
17836754	17836777	17	-	27260156	BXPC3	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.09495432117989122	[311]	[260,299,282,390]	-2	hSpCas9	negative selection	5573034
17823517	17823540	17	-	27260156	BXPC3	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.223104210845807	[771]	[826,895,904,1177]	5	hSpCas9	negative selection	5573035
17817268	17817291	17	+	27260156	BXPC3	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.3832590237724102	[593]	[420,483,359,662]	-7	hSpCas9	negative selection	5637288
17817285	17817308	17	-	27260156	BXPC3	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.14372454552245228	[785]	[742,669,745,825]	-3	hSpCas9	negative selection	5637289
17823541	17823564	17	-	27260156	BXPC3	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.1412039084130967	[91]	[64,94,82,109]	-3	hSpCas9	negative selection	5637290
17836726	17836749	17	-	27260156	A673	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.3682589354790178	[37]	[69,32,93,38]	8	hSpCas9	negative selection	5694284
17836754	17836777	17	-	27260156	A673	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.18602875555884923	[311]	[346,311,345,312]	-4	hSpCas9	negative selection	5694285
17823517	17823540	17	-	27260156	A673	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.4359419754873062	[771]	[1408,1061,1366,1193]	8	hSpCas9	negative selection	5694286
17817268	17817291	17	+	27260156	A673	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.09015084983949018	[593]	[660,679,629,708]	-2	hSpCas9	negative selection	5758539
17817285	17817308	17	-	27260156	A673	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.3031199531232631	[785]	[724,840,705,780]	-6	hSpCas9	negative selection	5758540
17823541	17823564	17	-	27260156	A673	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.12877546116026872	[91]	[125,123,104,128]	3	hSpCas9	negative selection	5758541
17836726	17836749	17	-	27260156	A375	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	1.1572133364125414	[37]	[222,107,34,38]	9	hSpCas9	negative selection	5815535
17836754	17836777	17	-	27260156	A375	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.3072943747250704	[311]	[397,719,362,367]	4	hSpCas9	negative selection	5815536
17823517	17823540	17	-	27260156	A375	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.04762460038067906	[771]	[845,939,972,961]	0	hSpCas9	negative selection	5815537
17817268	17817291	17	+	27260156	A375	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-1.2195417857061241	[593]	[342,347,228,279]	-8	hSpCas9	negative selection	5879790
17817285	17817308	17	-	27260156	A375	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.40268437874766616	[785]	[600,893,675,637]	-5	hSpCas9	negative selection	5879791
17823541	17823564	17	-	27260156	A375	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.8302426679644981	[91]	[99,6,81,46]	-8	hSpCas9	negative selection	5879792
17836726	17836749	17	-	27260156	COLO741	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-0.431295892652769	[37]	[33,26,45]	-7	hSpCas9	negative selection	5936786
17836754	17836777	17	-	27260156	COLO741	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.08297302213052615	[311]	[297,380,437]	-2	hSpCas9	negative selection	5936787
17823517	17823540	17	-	27260156	COLO741	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.3716750593559457	[771]	[1429,1374,1050]	7	hSpCas9	negative selection	5936788
17817268	17817291	17	+	27260156	COLO741	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.08056737147652476	[593]	[1088,655,692]	1	hSpCas9	negative selection	6001041
17817285	17817308	17	-	27260156	COLO741	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	0.029879777213021264	[785]	[820,1172,1059]	0	hSpCas9	negative selection	6001042
17823541	17823564	17	-	27260156	COLO741	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.18552327800353474	[91]	[110,169,118]	4	hSpCas9	negative selection	6001043
17836726	17836749	17	-	27260156	CAL120	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-0.7332375548356742	[37]	[14,22,44]	-8	hSpCas9	negative selection	6058037
17836754	17836777	17	-	27260156	CAL120	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.6005246246430832	[311]	[230,260,271]	-7	hSpCas9	negative selection	6058038
17823517	17823540	17	-	27260156	CAL120	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.15941004329651665	[771]	[1409,954,906]	2	hSpCas9	negative selection	6058039
17817268	17817291	17	+	27260156	CAL120	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-1.7440506013001396	[593]	[282,207,180]	-9	hSpCas9	negative selection	6122292
17817285	17817308	17	-	27260156	CAL120	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.6958416447962674	[785]	[700,641,484]	-7	hSpCas9	negative selection	6122293
17823541	17823564	17	-	27260156	CAL120	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.10957496207961936	[91]	[69,88,152]	-2	hSpCas9	negative selection	6122294
17836726	17836749	17	-	27260156	CADOES1	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.828709167819762	[37]	[46,46,70,86]	9	hSpCas9	negative selection	6179288
17836754	17836777	17	-	27260156	CADOES1	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.03749517828483617	[311]	[351,169,236,374]	0	hSpCas9	negative selection	6179289
17823517	17823540	17	-	27260156	CADOES1	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.3881446235066963	[771]	[864,1156,881,851]	6	hSpCas9	negative selection	6179290
17817268	17817291	17	+	27260156	CADOES1	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.28052935788222405	[593]	[977,507,730,457]	5	hSpCas9	negative selection	6243543
17817285	17817308	17	-	27260156	CADOES1	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.2567211767095449	[785]	[554,771,532,586]	-4	hSpCas9	negative selection	6243544
17823541	17823564	17	-	27260156	CADOES1	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.045410199024593645	[91]	[117,82,66,84]	0	hSpCas9	negative selection	6243545
17836726	17836749	17	-	27260156	EWS502	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.5234568147105896	[37]	[62,72,29,63]	8	hSpCas9	negative selection	6300539
17836754	17836777	17	-	27260156	EWS502	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.004211503897087021	[311]	[301,368,377,273]	0	hSpCas9	negative selection	6300540
17823517	17823540	17	-	27260156	EWS502	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.36576603332074176	[771]	[935,1031,1185,1074]	6	hSpCas9	negative selection	6300541
17817268	17817291	17	+	27260156	EWS502	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.07273949479220643	[593]	[519,551,633,703]	-1	hSpCas9	negative selection	6364794
17817285	17817308	17	-	27260156	EWS502	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.15978765397964179	[785]	[663,798,715,810]	-3	hSpCas9	negative selection	6364795
17823541	17823564	17	-	27260156	EWS502	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.026850838399875343	[91]	[100,125,85,64]	0	hSpCas9	negative selection	6364796
17836726	17836749	17	-	27260156	EW8	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.5263873672160426	[37]	[90,28,28,35]	8	hSpCas9	negative selection	6421790
17836754	17836777	17	-	27260156	EW8	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.045708469940901164	[311]	[325,213,225,289]	0	hSpCas9	negative selection	6421791
17823517	17823540	17	-	27260156	EW8	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.15533757604569054	[771]	[757,623,740,660]	3	hSpCas9	negative selection	6421792
17817268	17817291	17	+	27260156	EW8	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.3230716266440614	[593]	[310,527,293,412]	-6	hSpCas9	negative selection	6486045
17817285	17817308	17	-	27260156	EW8	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.29924793269148803	[785]	[662,496,399,544]	-5	hSpCas9	negative selection	6486046
17823541	17823564	17	-	27260156	EW8	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.10198100093895457	[91]	[51,32,125,54]	-2	hSpCas9	negative selection	6486047
17836726	17836749	17	-	27260156	CORL105	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-0.13700082363690136	[37]	[40,47,60,14]	-3	hSpCas9	negative selection	6543041
17836754	17836777	17	-	27260156	CORL105	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.14813754330335638	[311]	[447,352,408,411]	2	hSpCas9	negative selection	6543042
17823517	17823540	17	-	27260156	CORL105	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.21776526459917123	[771]	[967,927,1285,1057]	4	hSpCas9	negative selection	6543043
17817268	17817291	17	+	27260156	CORL105	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.00747765506449849	[593]	[618,816,599,738]	0	hSpCas9	negative selection	6607296
17817285	17817308	17	-	27260156	CORL105	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.2340460573200135	[785]	[784,996,538,765]	-4	hSpCas9	negative selection	6607297
17823541	17823564	17	-	27260156	CORL105	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.21900165766261548	[91]	[87,71,140,76]	-4	hSpCas9	negative selection	6607298
17836726	17836749	17	-	27260156	HS294T	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.7706695264295167	[37]	[10,6,64,17]	8	hSpCas9	negative selection	6664292
17836754	17836777	17	-	27260156	HS294T	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.28604263547336906	[311]	[169,101,173,139]	4	hSpCas9	negative selection	6664293
17823517	17823540	17	-	27260156	HS294T	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.34568109740213626	[771]	[331,389,394,407]	4	hSpCas9	negative selection	6664294
17817268	17817291	17	+	27260156	HS294T	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.7853844849598288	[593]	[116,92,149,183]	-8	hSpCas9	negative selection	6728547
17817285	17817308	17	-	27260156	HS294T	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.3188843542859488	[785]	[260,178,206,343]	-4	hSpCas9	negative selection	6728548
17823541	17823564	17	-	27260156	HS294T	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.1450713511180246	[91]	[44,25,31,22]	-2	hSpCas9	negative selection	6728549
17836726	17836749	17	-	27260156	HCC44	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.3108148345297721	[37]	[85,25,34,68]	5	hSpCas9	negative selection	6785543
17836754	17836777	17	-	27260156	HCC44	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.21058430124081512	[311]	[554,344,385,363]	3	hSpCas9	negative selection	6785544
17823517	17823540	17	-	27260156	HCC44	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.4367190275928887	[771]	[1222,1017,1582,995]	7	hSpCas9	negative selection	6785545
17817268	17817291	17	+	27260156	HCC44	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.5833838747809692	[593]	[383,315,457,639]	-7	hSpCas9	negative selection	6849798
17817285	17817308	17	-	27260156	HCC44	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.10056757595580379	[785]	[1152,786,736,657]	-2	hSpCas9	negative selection	6849799
17823541	17823564	17	-	27260156	HCC44	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.4896682536732566	[91]	[173,38,50,42]	-6	hSpCas9	negative selection	6849800
17836726	17836749	17	-	27260156	G402	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.8282638270073752	[37]	[126,46,89,69]	8	hSpCas9	negative selection	6906794
17836754	17836777	17	-	27260156	G402	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.22477354499826935	[311]	[838,486,337,185]	3	hSpCas9	negative selection	6906795
17823517	17823540	17	-	27260156	G402	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.4453618683121312	[771]	[1444,1299,1203,1204]	5	hSpCas9	negative selection	6906796
17817268	17817291	17	+	27260156	G402	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.2238459981699632	[593]	[555,829,646,457]	-3	hSpCas9	negative selection	6971049
17817285	17817308	17	-	27260156	G402	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	0.03938335185632358	[785]	[574,1460,906,964]	0	hSpCas9	negative selection	6971050
17823541	17823564	17	-	27260156	G402	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.23059748952272674	[91]	[250,133,11,145]	3	hSpCas9	negative selection	6971051
17836726	17836749	17	-	27260156	L33	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.9696267960097691	[37]	[25,29,59,103]	9	hSpCas9	negative selection	7028045
17836754	17836777	17	-	27260156	L33	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.0035859718979348587	[311]	[306,112,234,294]	0	hSpCas9	negative selection	7028046
17823517	17823540	17	-	27260156	L33	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.23246647918178542	[771]	[899,354,580,936]	5	hSpCas9	negative selection	7028047
17817268	17817291	17	+	27260156	L33	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.059491727154490526	[593]	[632,237,419,593]	1	hSpCas9	negative selection	7092300
17817285	17817308	17	-	27260156	L33	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.32352725210026245	[785]	[710,235,382,613]	-6	hSpCas9	negative selection	7092301
17823541	17823564	17	-	27260156	L33	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.1392408665382634	[91]	[58,25,60,114]	-3	hSpCas9	negative selection	7092302
17836726	17836749	17	-	27260156	K562	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-1.1012619537432284	[37]	[0,42,2,15]	-8	hSpCas9	negative selection	7149296
17836754	17836777	17	-	27260156	K562	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.3364044072724598	[311]	[197,313,58,298]	-4	hSpCas9	negative selection	7149297
17823517	17823540	17	-	27260156	K562	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.08858975007447456	[771]	[691,644,465,1060]	1	hSpCas9	negative selection	7149298
17817268	17817291	17	+	27260156	K562	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-2.0547258867675517	[593]	[179,167,118,54]	-9	hSpCas9	negative selection	7213551
17817285	17817308	17	-	27260156	K562	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	0.11463333071071735	[785]	[522,801,1344,375]	1	hSpCas9	negative selection	7213552
17823541	17823564	17	-	27260156	K562	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-1.428008638622598	[91]	[17,41,31,28]	-9	hSpCas9	negative selection	7213553
17836726	17836749	17	-	27260156	HT29	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-0.1483958346510934	[37]	[44,77,33,15]	-3	hSpCas9	negative selection	7270547
17836754	17836777	17	-	27260156	HT29	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.2732910622602227	[311]	[235,403,365,255]	-5	hSpCas9	negative selection	7270548
17823517	17823540	17	-	27260156	HT29	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.15112648725593103	[771]	[1435,1034,897,845]	3	hSpCas9	negative selection	7270549
17817268	17817291	17	+	27260156	HT29	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-1.2482093358969097	[593]	[342,314,303,260]	-9	hSpCas9	negative selection	7334802
17817285	17817308	17	-	27260156	HT29	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.611815501444584	[785]	[770,471,460,771]	-7	hSpCas9	negative selection	7334803
17823541	17823564	17	-	27260156	HT29	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.586651973997002	[91]	[60,110,66,61]	-7	hSpCas9	negative selection	7334804
17836726	17836749	17	-	27260156	MHHES1	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.37950745286913934	[37]	[32,80,4,92]	6	hSpCas9	negative selection	7391798
17836754	17836777	17	-	27260156	MHHES1	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.26034873907058137	[311]	[443,547,414,308]	5	hSpCas9	negative selection	7391799
17823517	17823540	17	-	27260156	MHHES1	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.44388141260595737	[771]	[1241,1334,1230,968]	7	hSpCas9	negative selection	7391800
17817268	17817291	17	+	27260156	MHHES1	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.12053256700509349	[593]	[676,796,566,466]	-2	hSpCas9	negative selection	7456053
17817285	17817308	17	-	27260156	MHHES1	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.043334075756803814	[785]	[1092,941,744,707]	-1	hSpCas9	negative selection	7456054
17823541	17823564	17	-	27260156	MHHES1	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.2226378604524668	[91]	[144,86,140,109]	4	hSpCas9	negative selection	7456055
17836726	17836749	17	-	27260156	MEWO	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-0.17070395019153528	[37]	[6,27,54]	-4	hSpCas9	negative selection	7513049
17836754	17836777	17	-	27260156	MEWO	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.028875052882477714	[311]	[424,290,201]	0	hSpCas9	negative selection	7513050
17823517	17823540	17	-	27260156	MEWO	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.4040214039908756	[771]	[1282,799,847]	8	hSpCas9	negative selection	7513051
17817268	17817291	17	+	27260156	MEWO	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.02549700070212002	[593]	[649,544,462]	0	hSpCas9	negative selection	7577304
17817285	17817308	17	-	27260156	MEWO	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.10377906992199148	[785]	[633,896,510]	-2	hSpCas9	negative selection	7577305
17823541	17823564	17	-	27260156	MEWO	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.014848021234594277	[91]	[62,132,59]	0	hSpCas9	negative selection	7577306
17836726	17836749	17	-	27260156	LNCAPCLONEFGC	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.35521416089666413	[37]	[53,27,50,44]	5	hSpCas9	negative selection	7634300
17836754	17836777	17	-	27260156	LNCAPCLONEFGC	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.295556615115569	[311]	[440,208,443,314]	4	hSpCas9	negative selection	7634301
17823517	17823540	17	-	27260156	LNCAPCLONEFGC	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.016744671837748526	[771]	[780,679,748,625]	0	hSpCas9	negative selection	7634302
17817268	17817291	17	+	27260156	LNCAPCLONEFGC	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.5723698265678101	[593]	[333,379,465,281]	-7	hSpCas9	negative selection	7698555
17817285	17817308	17	-	27260156	LNCAPCLONEFGC	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.22558231484796887	[785]	[407,561,619,853]	-4	hSpCas9	negative selection	7698556
17823541	17823564	17	-	27260156	LNCAPCLONEFGC	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.8492105897038669	[91]	[59,28,73,26]	-8	hSpCas9	negative selection	7698557
17836726	17836749	17	-	27260156	PANC0327	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-0.10768800144739066	[37]	[56,41,8,17]	-2	hSpCas9	negative selection	7755551
17836754	17836777	17	-	27260156	PANC0327	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.12211084610600625	[311]	[442,207,245,332]	1	hSpCas9	negative selection	7755552
17823517	17823540	17	-	27260156	PANC0327	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	-0.30366584672376934	[771]	[573,646,532,457]	-4	hSpCas9	negative selection	7755553
17817268	17817291	17	+	27260156	PANC0327	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.680610514319435	[593]	[388,333,310,286]	-7	hSpCas9	negative selection	7819806
17817285	17817308	17	-	27260156	PANC0327	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.5988455385210936	[785]	[539,361,394,565]	-7	hSpCas9	negative selection	7819807
17823541	17823564	17	-	27260156	PANC0327	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.4971580427148008	[91]	[95,24,74,42]	-6	hSpCas9	negative selection	7819808
17836726	17836749	17	-	27260156	NCIH2009	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.9669273723908516	[37]	[102,158,47]	9	hSpCas9	negative selection	7876802
17836754	17836777	17	-	27260156	NCIH2009	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.07047761028902422	[311]	[616,507,277]	1	hSpCas9	negative selection	7876803
17823517	17823540	17	-	27260156	NCIH2009	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.24660963563380112	[771]	[1398,917,1549]	3	hSpCas9	negative selection	7876804
17817268	17817291	17	+	27260156	NCIH2009	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.6438088104486959	[593]	[502,586,495]	-7	hSpCas9	negative selection	7941057
17817285	17817308	17	-	27260156	NCIH2009	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.3453673133595482	[785]	[964,673,975]	-5	hSpCas9	negative selection	7941058
17823541	17823564	17	-	27260156	NCIH2009	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.19913031412701843	[91]	[74,262,87]	2	hSpCas9	negative selection	7941059
17836726	17836749	17	-	27260156	NCIH1373	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.24764466527719042	[37]	[99,21,9,21]	2	hSpCas9	negative selection	7998053
17836754	17836777	17	-	27260156	NCIH1373	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.40590280749913543	[311]	[355,184,367,41]	-4	hSpCas9	negative selection	7998054
17823517	17823540	17	-	27260156	NCIH1373	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.11591894175016271	[771]	[924,987,658,311]	1	hSpCas9	negative selection	7998055
17817268	17817291	17	+	27260156	NCIH1373	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-2.00616368554788	[593]	[129,90,147,79]	-9	hSpCas9	negative selection	8062308
17817285	17817308	17	-	27260156	NCIH1373	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.4954367745665823	[785]	[760,408,936,108]	-5	hSpCas9	negative selection	8062309
17823541	17823564	17	-	27260156	NCIH1373	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.24202826024238933	[91]	[112,136,17,20]	-2	hSpCas9	negative selection	8062310
17836726	17836749	17	-	27260156	PATU8902	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.740516543979056	[37]	[91,76,152,3]	7	hSpCas9	negative selection	8119304
17836754	17836777	17	-	27260156	PATU8902	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-1.1729362823948457	[311]	[117,392,101,179]	-8	hSpCas9	negative selection	8119305
17823517	17823540	17	-	27260156	PATU8902	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.001341311431392822	[771]	[1031,1117,697,1610]	0	hSpCas9	negative selection	8119306
17817268	17817291	17	+	27260156	PATU8902	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-2.1938881850653287	[593]	[139,291,210,56]	-9	hSpCas9	negative selection	8183559
17817285	17817308	17	-	27260156	PATU8902	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.4367461739670184	[785]	[970,492,805,975]	-4	hSpCas9	negative selection	8183560
17823541	17823564	17	-	27260156	PATU8902	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-1.3109925794219324	[91]	[6,88,4,126]	-8	hSpCas9	negative selection	8183561
17836726	17836749	17	-	27260156	PANC1	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.42186096943471085	[37]	[8,80,90,7]	6	hSpCas9	negative selection	8240555
17836754	17836777	17	-	27260156	PANC1	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.151485993417098	[311]	[173,321,313,179]	-2	hSpCas9	negative selection	8240556
17823517	17823540	17	-	27260156	PANC1	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	-0.15653228947090714	[771]	[518,810,550,542]	-3	hSpCas9	negative selection	8240557
17817268	17817291	17	+	27260156	PANC1	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-1.4085629196163079	[593]	[165,222,115,255]	-9	hSpCas9	negative selection	8304810
17817285	17817308	17	-	27260156	PANC1	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-1.0375880934847113	[785]	[325,355,354,285]	-8	hSpCas9	negative selection	8304811
17823541	17823564	17	-	27260156	PANC1	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.9608731949591096	[91]	[42,57,55,12]	-8	hSpCas9	negative selection	8304812
17836726	17836749	17	-	27260156	PANC0813	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.6716498754946487	[37]	[116,127,5,38]	9	hSpCas9	negative selection	8361806
17836754	17836777	17	-	27260156	PANC0813	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.15175622738088512	[311]	[241,328,370,366]	-2	hSpCas9	negative selection	8361807
17823517	17823540	17	-	27260156	PANC0813	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.4582470993040122	[771]	[1003,1225,983,1716]	7	hSpCas9	negative selection	8361808
17817268	17817291	17	+	27260156	PANC0813	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-1.1358879884833788	[593]	[212,358,334,350]	-9	hSpCas9	negative selection	8426061
17817285	17817308	17	-	27260156	PANC0813	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.21630358312329234	[785]	[1173,735,604,701]	-3	hSpCas9	negative selection	8426062
17823541	17823564	17	-	27260156	PANC0813	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.2896498654621662	[91]	[113,158,96,154]	5	hSpCas9	negative selection	8426063
17836726	17836749	17	-	27260156	RDES	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.9564931110668082	[37]	[62,97,97,80]	9	hSpCas9	negative selection	8483057
17836754	17836777	17	-	27260156	RDES	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.35221092386736874	[311]	[386,480,450,520]	5	hSpCas9	negative selection	8483058
17823517	17823540	17	-	27260156	RDES	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.16375423122442778	[771]	[923,933,986,1143]	2	hSpCas9	negative selection	8483059
17817268	17817291	17	+	27260156	RDES	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.0006334515415778452	[593]	[644,672,787,605]	0	hSpCas9	negative selection	8547312
17817285	17817308	17	-	27260156	RDES	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.12078879461892922	[785]	[655,924,747,1025]	-2	hSpCas9	negative selection	8547313
17823541	17823564	17	-	27260156	RDES	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.34295793203028335	[91]	[41,157,66,61]	-5	hSpCas9	negative selection	8547314
17836726	17836749	17	-	27260156	PC3	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	-0.18832388689025414	[37]	[15,73,15,21]	-4	hSpCas9	negative selection	8604308
17836754	17836777	17	-	27260156	PC3	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.3762819473344816	[311]	[166,450,935,338]	7	hSpCas9	negative selection	8604309
17823517	17823540	17	-	27260156	PC3	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.36998117446054546	[771]	[672,931,1533,1093]	7	hSpCas9	negative selection	8604310
17817268	17817291	17	+	27260156	PC3	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.23136339270283507	[593]	[372,868,1035,705]	5	hSpCas9	negative selection	8668563
17817285	17817308	17	-	27260156	PC3	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.22935545776897925	[785]	[412,756,710,857]	-5	hSpCas9	negative selection	8668564
17823541	17823564	17	-	27260156	PC3	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.15933306568625394	[91]	[53,75,195,135]	3	hSpCas9	negative selection	8668565
17836726	17836749	17	-	27260156	PATU8988T	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.03332392572052845	[37]	[6,6,71,62]	0	hSpCas9	negative selection	8725559
17836754	17836777	17	-	27260156	PATU8988T	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.4749000337141479	[311]	[235,228,198,203]	-6	hSpCas9	negative selection	8725560
17823517	17823540	17	-	27260156	PATU8988T	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	-0.046604185320263225	[771]	[650,1002,577,681]	-1	hSpCas9	negative selection	8725561
17817268	17817291	17	+	27260156	PATU8988T	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-1.1323437176877047	[593]	[239,139,392,260]	-9	hSpCas9	negative selection	8789814
17817285	17817308	17	-	27260156	PATU8988T	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.2966226717946539	[785]	[822,644,450,553]	-5	hSpCas9	negative selection	8789815
17823541	17823564	17	-	27260156	PATU8988T	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-1.2517816144258007	[91]	[32,44,54,14]	-9	hSpCas9	negative selection	8789816
17836726	17836749	17	-	27260156	T47D	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.35476517958852627	[37]	[46,53,56,68]	7	hSpCas9	negative selection	8846810
17836754	17836777	17	-	27260156	T47D	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.012453359351508597	[311]	[372,358,361,346]	0	hSpCas9	negative selection	8846811
17823517	17823540	17	-	27260156	T47D	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.47707821538027284	[771]	[1293,1107,1260,1359]	8	hSpCas9	negative selection	8846812
17817268	17817291	17	+	27260156	T47D	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.5149302270231237	[593]	[521,402,501,517]	-8	hSpCas9	negative selection	8911065
17817285	17817308	17	-	27260156	T47D	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.31369738220778204	[785]	[700,792,792,650]	-6	hSpCas9	negative selection	8911066
17823541	17823564	17	-	27260156	T47D	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.07540012597671497	[91]	[133,110,76,83]	-2	hSpCas9	negative selection	8911067
17836726	17836749	17	-	27260156	SU8686	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.845630520481548	[37]	[77,47,71,74]	9	hSpCas9	negative selection	8968061
17836754	17836777	17	-	27260156	SU8686	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.4589239479544983	[311]	[166,231,236,276]	-6	hSpCas9	negative selection	8968062
17823517	17823540	17	-	27260156	SU8686	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.3596901875154199	[771]	[1060,788,882,1243]	6	hSpCas9	negative selection	8968063
17817268	17817291	17	+	27260156	SU8686	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-1.5408571263329203	[593]	[273,222,101,193]	-9	hSpCas9	negative selection	9032316
17817285	17817308	17	-	27260156	SU8686	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.645765380701014	[785]	[545,391,541,521]	-7	hSpCas9	negative selection	9032317
17823541	17823564	17	-	27260156	SU8686	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.1809840871872055	[91]	[107,101,94,107]	3	hSpCas9	negative selection	9032318
17836726	17836749	17	-	27260156	SKES1	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.003077992890279102	[37]	[14,49,49,34]	0	hSpCas9	negative selection	9089312
17836754	17836777	17	-	27260156	SKES1	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.00720128148854049	[311]	[370,315,308,265]	0	hSpCas9	negative selection	9089313
17823517	17823540	17	-	27260156	SKES1	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.2928083470999596	[771]	[1052,1134,846,786]	6	hSpCas9	negative selection	9089314
17817268	17817291	17	+	27260156	SKES1	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.095461937918979	[593]	[684,759,563,549]	2	hSpCas9	negative selection	9153567
17817285	17817308	17	-	27260156	SKES1	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.24584451011799796	[785]	[1044,727,463,485]	-5	hSpCas9	negative selection	9153568
17823541	17823564	17	-	27260156	SKES1	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.9411136107916898	[91]	[26,101,51,16]	-9	hSpCas9	negative selection	9153569
17836726	17836749	17	-	27260156	TOV112D	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.6963777919791783	[37]	[6,59,55,116]	9	hSpCas9	negative selection	9210563
17836754	17836777	17	-	27260156	TOV112D	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.178760426708231	[311]	[226,344,208,333]	-3	hSpCas9	negative selection	9210564
17823517	17823540	17	-	27260156	TOV112D	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.3090274286126915	[771]	[870,1302,1007,731]	6	hSpCas9	negative selection	9210565
17817268	17817291	17	+	27260156	TOV112D	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.034981154976660656	[593]	[810,615,395,631]	0	hSpCas9	negative selection	9274818
17817285	17817308	17	-	27260156	TOV112D	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	0.011081789111732743	[785]	[924,1306,669,417]	0	hSpCas9	negative selection	9274819
17823541	17823564	17	-	27260156	TOV112D	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.0471613730410021	[91]	[68,155,81,64]	-1	hSpCas9	negative selection	9274820
17836726	17836749	17	-	27260156	TC71	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.5562237097706131	[37]	[71,100,37,26]	9	hSpCas9	negative selection	9331814
17836754	17836777	17	-	27260156	TC71	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	-0.12825083831181305	[311]	[324,269,341,283]	-3	hSpCas9	negative selection	9331815
17823517	17823540	17	-	27260156	TC71	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.28803005912928414	[771]	[969,1079,995,995]	7	hSpCas9	negative selection	9331816
17817268	17817291	17	+	27260156	TC71	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	0.0478411309022741	[593]	[562,791,652,624]	1	hSpCas9	negative selection	9396069
17817285	17817308	17	-	27260156	TC71	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.2537998736863385	[785]	[680,724,542,894]	-6	hSpCas9	negative selection	9396070
17823541	17823564	17	-	27260156	TC71	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	0.06578734549771559	[91]	[83,105,146,72]	1	hSpCas9	negative selection	9396071
17836726	17836749	17	-	27260156	TC32	viability	GCGCTGCTGACCGACATCGAAGG	SREBF1	ENSG00000072310	0.2657431172015299	[37]	[31,37,55,48]	5	hSpCas9	negative selection	9453065
17836754	17836777	17	-	27260156	TC32	viability	GCTGGGCGAGCCGTGCGATCTGG	SREBF1	ENSG00000072310	0.20367549954386527	[311]	[212,314,419,425]	3	hSpCas9	negative selection	9453066
17823517	17823540	17	-	27260156	TC32	viability	GCCATGGATTGCACTTTCGAAGG	SREBF1	ENSG00000072310	0.45645127660422413	[771]	[848,865,1188,1124]	7	hSpCas9	negative selection	9453067
17817268	17817291	17	+	27260156	TC32	viability	TGCCCAGCACGTTGCGCCCAGGG	SREBF1	ENSG00000072310	-0.14294272658070264	[593]	[411,320,802,596]	-3	hSpCas9	negative selection	9517320
17817285	17817308	17	-	27260156	TC32	viability	ACCAGCGTCTACCATAGCCCTGG	SREBF1	ENSG00000072310	-0.332383634015661	[785]	[521,468,700,697]	-6	hSpCas9	negative selection	9517321
17823541	17823564	17	-	27260156	TC32	viability	CCAAGGGCGGGCGCAGATCGCGG	SREBF1	ENSG00000072310	-0.2835290636117289	[91]	[84,68,53,66]	-5	hSpCas9	negative selection	9517322
17819210	17819233	17	+	27869803	HPAFII	viability after 27 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.8994243268141293	[126]	[99,144,NaN]	7	hSpCas9	negative selection	9559377
17819338	17819361	17	+	27869803	HPAFII	viability after 27 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-2.1798234625085504	[350]	[55,27,NaN]	-8	hSpCas9	negative selection	9559378
17819638	17819661	17	+	27869803	HPAFII	viability after 27 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-1.41603040712319	[322]	[13,104,NaN]	-7	hSpCas9	negative selection	9559379
17820280	17820303	17	+	27869803	HPAFII	viability after 27 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	-1.164011397646548	[500]	[170,72,NaN]	-7	hSpCas9	negative selection	9559380
17823591	17823614	17	-	27869803	HPAFII	viability after 27 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.36817889888991034	[266]	[238,132,NaN]	3	hSpCas9	negative selection	9559381
17836790	17836813	17	-	27869803	HPAFII	viability after 27 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	1.0855722476718037	[270]	[465,165,NaN]	8	hSpCas9	negative selection	9559383
17819210	17819233	17	+	27869803	HPAFII	viability after 15 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.8712276618533722	[126]	[298,218,NaN]	8	hSpCas9	negative selection	9641826
17819338	17819361	17	+	27869803	HPAFII	viability after 15 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-0.9743390033375728	[350]	[191,191,NaN]	-7	hSpCas9	negative selection	9641827
17819638	17819661	17	+	27869803	HPAFII	viability after 15 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-0.8988634667969111	[322]	[253,143,NaN]	-7	hSpCas9	negative selection	9641828
17820280	17820303	17	+	27869803	HPAFII	viability after 15 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	-0.7380716642703837	[500]	[492,216,NaN]	-7	hSpCas9	negative selection	9641829
17823591	17823614	17	-	27869803	HPAFII	viability after 15 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.21858374645925965	[266]	[463,252,NaN]	2	hSpCas9	negative selection	9641830
17836790	17836813	17	-	27869803	HPAFII	viability after 15 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	0.7092351814864928	[270]	[773,290,NaN]	7	hSpCas9	negative selection	9641832
17819210	17819233	17	+	27869803	ASPC1	viability after 36 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	-1.2130789845113634	[458]	[125,41,49]	-8	hSpCas9	negative selection	9724275
17819338	17819361	17	+	27869803	ASPC1	viability after 36 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-0.29902804151780693	[935]	[632,92,141]	-3	hSpCas9	negative selection	9724276
17819638	17819661	17	+	27869803	ASPC1	viability after 36 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-0.42266785027926246	[834]	[190,332,141]	-4	hSpCas9	negative selection	9724277
17820280	17820303	17	+	27869803	ASPC1	viability after 36 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.21477009210257314	[1187]	[692,272,492]	2	hSpCas9	negative selection	9724278
17823591	17823614	17	-	27869803	ASPC1	viability after 36 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	-0.23814852143822807	[620]	[199,99,236]	-2	hSpCas9	negative selection	9724279
17836790	17836813	17	-	27869803	ASPC1	viability after 36 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	0.09248584020451744	[517]	[122,296,156]	0	hSpCas9	negative selection	9724281
17819210	17819233	17	+	27869803	PATU8988S	viability after 35 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	-0.3074212446538699	[368]	[160,78,NaN]	-3	hSpCas9	negative selection	9806724
17819338	17819361	17	+	27869803	PATU8988S	viability after 35 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-0.014560267729083809	[814]	[300,348,NaN]	0	hSpCas9	negative selection	9806725
17819638	17819661	17	+	27869803	PATU8988S	viability after 35 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	0.2515368048033037	[585]	[265,295,NaN]	3	hSpCas9	negative selection	9806726
17820280	17820303	17	+	27869803	PATU8988S	viability after 35 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.4847366192450955	[1009]	[663,473,NaN]	5	hSpCas9	negative selection	9806727
17823591	17823614	17	-	27869803	PATU8988S	viability after 35 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.6892702328382079	[540]	[498,202,NaN]	7	hSpCas9	negative selection	9806728
17836790	17836813	17	-	27869803	PATU8988S	viability after 35 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	-0.9607022537273338	[740]	[82,223,NaN]	-7	hSpCas9	negative selection	9806730
17819210	17819233	17	+	27869803	PATU8988S	viability after 31 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	-0.2444147014029654	[368]	[154,84,NaN]	-3	hSpCas9	negative selection	9889173
17819338	17819361	17	+	27869803	PATU8988S	viability after 31 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	0.33292730276829574	[814]	[257,601,NaN]	4	hSpCas9	negative selection	9889174
17819638	17819661	17	+	27869803	PATU8988S	viability after 31 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	0.20618557926047454	[585]	[280,254,NaN]	2	hSpCas9	negative selection	9889175
17820280	17820303	17	+	27869803	PATU8988S	viability after 31 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	0.4753301963024299	[1009]	[613,490,NaN]	6	hSpCas9	negative selection	9889176
17823591	17823614	17	-	27869803	PATU8988S	viability after 31 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.6787808277300369	[540]	[354,332,NaN]	7	hSpCas9	negative selection	9889177
17836790	17836813	17	-	27869803	PATU8988S	viability after 31 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	0.2832083501318354	[740]	[143,633,NaN]	3	hSpCas9	negative selection	9889179
17819210	17819233	17	+	27869803	HPAFII	viability after 35 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.038575369548367155	[126]	[18,118,NaN]	0	hSpCas9	negative selection	9971622
17819338	17819361	17	+	27869803	HPAFII	viability after 35 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-2.4259099593581603	[350]	[49,13,NaN]	-8	hSpCas9	negative selection	9971623
17819638	17819661	17	+	27869803	HPAFII	viability after 35 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-1.0169760702566462	[322]	[37,128,NaN]	-5	hSpCas9	negative selection	9971624
17820280	17820303	17	+	27869803	HPAFII	viability after 35 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	-1.5079644747790795	[500]	[91,85,NaN]	-7	hSpCas9	negative selection	9971625
17823591	17823614	17	-	27869803	HPAFII	viability after 35 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.2589175712475021	[266]	[228,85,NaN]	1	hSpCas9	negative selection	9971626
17836790	17836813	17	-	27869803	HPAFII	viability after 35 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	1.8038927838188477	[270]	[645,290,NaN]	9	hSpCas9	negative selection	9971628
17819210	17819233	17	+	27869803	HPAFII	viability after 31 days	AGATGGTTCCGCCACTCACCAGG	SREBF1	ENSG00000072310	0.28715613946167085	[126]	[63,111,NaN]	2	hSpCas9	negative selection	10054071
17819338	17819361	17	+	27869803	HPAFII	viability after 31 days	CACAGTGGTGCCAGAGACCAGGG	SREBF1	ENSG00000072310	-2.1207443760686924	[350]	[62,25,NaN]	-8	hSpCas9	negative selection	10054072
17819638	17819661	17	+	27869803	HPAFII	viability after 31 days	TGGGTGTGCAAGGAGACGGGCGG	SREBF1	ENSG00000072310	-2.0320866769459145	[322]	[17,72,NaN]	-8	hSpCas9	negative selection	10054073
17820280	17820303	17	+	27869803	HPAFII	viability after 31 days	CGGGTACATCTTCAATGGAGTGG	SREBF1	ENSG00000072310	-1.3139315910399305	[500]	[103,122,NaN]	-7	hSpCas9	negative selection	10054074
17823591	17823614	17	-	27869803	HPAFII	viability after 31 days	TGACAGGTGAAGTCGGCGCGGGG	SREBF1	ENSG00000072310	0.40914452894175335	[266]	[298,89,NaN]	3	hSpCas9	negative selection	10054075
17836790	17836813	17	-	27869803	HPAFII	viability after 31 days	CGAGCCACCCTTCAGCGAGGCGG	SREBF1	ENSG00000072310	1.1951721099096877	[270]	[509,171,NaN]	8	hSpCas9	negative selection	10054077
17820131	17820154	17	+	28162770	P31FUJ	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	3.52208529774909	[1]	[26]	9	hSpCas9	negative selection	10242857
17820368	17820391	17	+	28162770	P31FUJ	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-0.5201918805972623	[226]	[185]	-4	hSpCas9	negative selection	10242858
17820115	17820138	17	+	28162770	P31FUJ	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	0.2850461004482405	[87]	[125]	3	hSpCas9	negative selection	10242859
17820089	17820112	17	+	28162770	P31FUJ	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-0.7275668961639565	[309]	[219]	-5	hSpCas9	negative selection	10242860
17819339	17819362	17	+	28162770	P31FUJ	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-0.7727625805531261	[646]	[444]	-5	hSpCas9	negative selection	10242861
17817836	17817859	17	-	28162770	P31FUJ	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-2.040157126471983	[300]	[85]	-8	hSpCas9	negative selection	10242862
17816299	17816322	17	-	28162770	P31FUJ	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-0.07327237433444478	[324]	[362]	0	hSpCas9	negative selection	10242863
17815941	17815964	17	-	28162770	P31FUJ	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	0.5607469181181952	[254]	[441]	6	hSpCas9	negative selection	10242864
17836786	17836809	17	+	28162770	P31FUJ	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	0.6910261151002175	[174]	[331]	7	hSpCas9	negative selection	10242865
17820462	17820485	17	+	28162770	P31FUJ	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	0.793964705148407	[266]	[543]	8	hSpCas9	negative selection	10242866
17820131	17820154	17	+	28162770	TF1	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10412223
17820368	17820391	17	+	28162770	TF1	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	NaN	[NaN]	[184]	1	hSpCas9	negative selection	10412224
17820115	17820138	17	+	28162770	TF1	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10412225
17820089	17820112	17	+	28162770	TF1	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10412226
17819339	17819362	17	+	28162770	TF1	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10412227
17817836	17817859	17	-	28162770	TF1	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10412228
17816299	17816322	17	-	28162770	TF1	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10412229
17815941	17815964	17	-	28162770	TF1	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	NaN	[NaN]	[101]	1	hSpCas9	negative selection	10412230
17836786	17836809	17	+	28162770	TF1	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10412231
17820462	17820485	17	+	28162770	TF1	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10412232
17820131	17820154	17	+	28162770	SKM1	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10581589
17820368	17820391	17	+	28162770	SKM1	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-1.2473075327546763	[46]	[34]	-7	hSpCas9	negative selection	10581590
17820115	17820138	17	+	28162770	SKM1	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	-0.76953427812787	[26]	[27]	-5	hSpCas9	negative selection	10581591
17820089	17820112	17	+	28162770	SKM1	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-2.2370391973008497	[71]	[26]	-8	hSpCas9	negative selection	10581592
17819339	17819362	17	+	28162770	SKM1	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-0.9525037222561333	[184]	[168]	-6	hSpCas9	negative selection	10581593
17817836	17817859	17	-	28162770	SKM1	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-3.1245644680424367	[73]	[14]	-9	hSpCas9	negative selection	10581594
17816299	17816322	17	-	28162770	SKM1	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-1.6559917465830765	[81]	[45]	-8	hSpCas9	negative selection	10581595
17815941	17815964	17	-	28162770	SKM1	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	0.6804986425071777	[29]	[84]	6	hSpCas9	negative selection	10581596
17836786	17836809	17	+	28162770	SKM1	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	-1.0494121941250778	[47]	[40]	-6	hSpCas9	negative selection	10581597
17820462	17820485	17	+	28162770	SKM1	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	-1.2131924553464817	[79]	[60]	-7	hSpCas9	negative selection	10581598
17820131	17820154	17	+	28162770	SKM1	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10750955
17820368	17820391	17	+	28162770	SKM1	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-1.2473075327546763	[46]	[34]	-7	hSpCas9	negative selection	10750956
17820115	17820138	17	+	28162770	SKM1	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	-0.76953427812787	[26]	[27]	-5	hSpCas9	negative selection	10750957
17820089	17820112	17	+	28162770	SKM1	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-2.2370391973008497	[71]	[26]	-8	hSpCas9	negative selection	10750958
17819339	17819362	17	+	28162770	SKM1	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-0.9525037222561333	[184]	[168]	-6	hSpCas9	negative selection	10750959
17817836	17817859	17	-	28162770	SKM1	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-3.1245644680424367	[73]	[14]	-9	hSpCas9	negative selection	10750960
17816299	17816322	17	-	28162770	SKM1	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-1.6559917465830765	[81]	[45]	-8	hSpCas9	negative selection	10750961
17815941	17815964	17	-	28162770	SKM1	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	0.6804986425071777	[29]	[84]	6	hSpCas9	negative selection	10750962
17836786	17836809	17	+	28162770	SKM1	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	-1.0494121941250778	[47]	[40]	-6	hSpCas9	negative selection	10750963
17820462	17820485	17	+	28162770	SKM1	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	-1.2131924553464817	[79]	[60]	-7	hSpCas9	negative selection	10750964
17820131	17820154	17	+	28162770	PL21	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	2.4225320358257685	[2]	[6]	9	hSpCas9	negative selection	10920321
17820368	17820391	17	+	28162770	PL21	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	0.4656635723488118	[192]	[115]	4	hSpCas9	negative selection	10920322
17820115	17820138	17	+	28162770	PL21	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	-0.725859804066903	[113]	[29]	-5	hSpCas9	negative selection	10920323
17820089	17820112	17	+	28162770	PL21	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-1.302360726039863	[288]	[50]	-7	hSpCas9	negative selection	10920324
17819339	17819362	17	+	28162770	PL21	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-1.4301468767413263	[581]	[93]	-7	hSpCas9	negative selection	10920325
17817836	17817859	17	-	28162770	PL21	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-0.724955576496789	[318]	[83]	-5	hSpCas9	negative selection	10920326
17816299	17816322	17	-	28162770	PL21	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-0.7666935215754804	[171]	[43]	-5	hSpCas9	negative selection	10920327
17815941	17815964	17	-	28162770	PL21	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	-3.1010299202312446	[137]	[6]	-9	hSpCas9	negative selection	10920328
17836786	17836809	17	+	28162770	PL21	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	1.3904708265934695	[77]	[88]	9	hSpCas9	negative selection	10920329
17820462	17820485	17	+	28162770	PL21	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	-0.6229826234266005	[229]	[64]	-4	hSpCas9	negative selection	10920330
17820131	17820154	17	+	28162770	P31FUJ	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	3.52208529774909	[1]	[26]	9	hSpCas9	negative selection	11089687
17820368	17820391	17	+	28162770	P31FUJ	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-0.5201918805972623	[226]	[185]	-4	hSpCas9	negative selection	11089688
17820115	17820138	17	+	28162770	P31FUJ	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	0.2850461004482405	[87]	[125]	3	hSpCas9	negative selection	11089689
17820089	17820112	17	+	28162770	P31FUJ	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-0.7275668961639565	[309]	[219]	-5	hSpCas9	negative selection	11089690
17819339	17819362	17	+	28162770	P31FUJ	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-0.7727625805531261	[646]	[444]	-5	hSpCas9	negative selection	11089691
17817836	17817859	17	-	28162770	P31FUJ	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-2.040157126471983	[300]	[85]	-8	hSpCas9	negative selection	11089692
17816299	17816322	17	-	28162770	P31FUJ	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-0.07327237433444478	[324]	[362]	0	hSpCas9	negative selection	11089693
17815941	17815964	17	-	28162770	P31FUJ	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	0.5607469181181952	[254]	[441]	6	hSpCas9	negative selection	11089694
17836786	17836809	17	+	28162770	P31FUJ	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	0.6910261151002175	[174]	[331]	7	hSpCas9	negative selection	11089695
17820462	17820485	17	+	28162770	P31FUJ	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	0.793964705148407	[266]	[543]	8	hSpCas9	negative selection	11089696
17820131	17820154	17	+	28162770	OCIAML5	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11259053
17820368	17820391	17	+	28162770	OCIAML5	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	0.35587469417491047	[128]	[297]	3	hSpCas9	negative selection	11259054
17820115	17820138	17	+	28162770	OCIAML5	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	0.03455162971826059	[85]	[158]	0	hSpCas9	negative selection	11259055
17820089	17820112	17	+	28162770	OCIAML5	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-1.3644012714977558	[183]	[128]	-7	hSpCas9	negative selection	11259056
17819339	17819362	17	+	28162770	OCIAML5	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-0.6947102429247405	[268]	[299]	-4	hSpCas9	negative selection	11259057
17817836	17817859	17	-	28162770	OCIAML5	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-1.9912293185356225	[173]	[78]	-8	hSpCas9	negative selection	11259058
17816299	17816322	17	-	28162770	OCIAML5	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-1.4226020009498734	[198]	[133]	-7	hSpCas9	negative selection	11259059
17815941	17815964	17	-	28162770	OCIAML5	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	1.06993091713473	[75]	[287]	8	hSpCas9	negative selection	11259060
17836786	17836809	17	+	28162770	OCIAML5	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	-0.04761737998180382	[70]	[123]	0	hSpCas9	negative selection	11259061
17820462	17820485	17	+	28162770	OCIAML5	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	-0.033513442201528965	[164]	[290]	0	hSpCas9	negative selection	11259062
17820131	17820154	17	+	28162770	EOL1	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	1.924547771570535	[0]	[1]	9	hSpCas9	negative selection	11428419
17820368	17820391	17	+	28162770	EOL1	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	0.5872195833894266	[258]	[204]	5	hSpCas9	negative selection	11428420
17820115	17820138	17	+	28162770	EOL1	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	-0.07545222842946542	[187]	[93]	0	hSpCas9	negative selection	11428421
17820089	17820112	17	+	28162770	EOL1	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	0.11557093248894046	[444]	[253]	1	hSpCas9	negative selection	11428422
17819339	17819362	17	+	28162770	EOL1	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-0.7240733663729393	[1250]	[398]	-5	hSpCas9	negative selection	11428423
17817836	17817859	17	-	28162770	EOL1	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-0.8719188343443335	[527]	[151]	-6	hSpCas9	negative selection	11428424
17816299	17816322	17	-	28162770	EOL1	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	0.7370459969040983	[319]	[280]	6	hSpCas9	negative selection	11428425
17815941	17815964	17	-	28162770	EOL1	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	1.2526019692547385	[187]	[235]	9	hSpCas9	negative selection	11428426
17836786	17836809	17	+	28162770	EOL1	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	-0.0843303797759184	[162]	[80]	0	hSpCas9	negative selection	11428427
17820462	17820485	17	+	28162770	EOL1	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	0.11415025778931293	[355]	[202]	1	hSpCas9	negative selection	11428428
17820131	17820154	17	+	28162770	MOLM13	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	-2.1170731191765775	[5]	[0]	-7	hSpCas9	negative selection	11597785
17820368	17820391	17	+	28162770	MOLM13	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-2.5835388572624245	[256]	[30]	-8	hSpCas9	negative selection	11597786
17820115	17820138	17	+	28162770	MOLM13	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	-3.991542237092718	[131]	[5]	-9	hSpCas9	negative selection	11597787
17820089	17820112	17	+	28162770	MOLM13	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-1.2586272633905964	[320]	[96]	-6	hSpCas9	negative selection	11597788
17819339	17819362	17	+	28162770	MOLM13	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-2.199899550306198	[698]	[109]	-7	hSpCas9	negative selection	11597789
17817836	17817859	17	-	28162770	MOLM13	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-1.8325055517931421	[398]	[80]	-7	hSpCas9	negative selection	11597790
17816299	17816322	17	-	28162770	MOLM13	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-7.736681762704626	[294]	[0]	-9	hSpCas9	negative selection	11597791
17815941	17815964	17	-	28162770	MOLM13	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	0.11760809060797695	[166]	[130]	0	hSpCas9	negative selection	11597792
17836786	17836809	17	+	28162770	MOLM13	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	-0.8498509163793503	[171]	[68]	-5	hSpCas9	negative selection	11597793
17820462	17820485	17	+	28162770	MOLM13	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	-4.138383625421989	[340]	[13]	-9	hSpCas9	negative selection	11597794
17820131	17820154	17	+	28162770	HEL	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	-1.357261167999643	[3]	[0]	-7	hSpCas9	negative selection	11767151
17820368	17820391	17	+	28162770	HEL	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-0.5299957030287794	[256]	[113]	-4	hSpCas9	negative selection	11767152
17820115	17820138	17	+	28162770	HEL	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	-1.0748614372989178	[147]	[44]	-6	hSpCas9	negative selection	11767153
17820089	17820112	17	+	28162770	HEL	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-0.9147429322986922	[311]	[105]	-5	hSpCas9	negative selection	11767154
17819339	17819362	17	+	28162770	HEL	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-1.5581298766502236	[753]	[163]	-7	hSpCas9	negative selection	11767155
17817836	17817859	17	-	28162770	HEL	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-3.869711168936431	[387]	[16]	-9	hSpCas9	negative selection	11767156
17816299	17816322	17	-	28162770	HEL	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-1.2211996184236145	[272]	[74]	-6	hSpCas9	negative selection	11767157
17815941	17815964	17	-	28162770	HEL	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	1.4021990639536497	[139]	[236]	9	hSpCas9	negative selection	11767158
17836786	17836809	17	+	28162770	HEL	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	0.014707609387314746	[152]	[98]	0	hSpCas9	negative selection	11767159
17820462	17820485	17	+	28162770	HEL	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	-0.3239025710532119	[341]	[174]	-2	hSpCas9	negative selection	11767160
17820131	17820154	17	+	28162770	MV411	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	-1.7525624492172245	[3]	[0]	-8	hSpCas9	negative selection	11936517
17820368	17820391	17	+	28162770	MV411	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-0.8492384686288986	[215]	[100]	-5	hSpCas9	negative selection	11936518
17820115	17820138	17	+	28162770	MV411	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	-0.5230806030944573	[86]	[50]	-4	hSpCas9	negative selection	11936519
17820089	17820112	17	+	28162770	MV411	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-1.6270315671333657	[186]	[50]	-7	hSpCas9	negative selection	11936520
17819339	17819362	17	+	28162770	MV411	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-1.8252399537038928	[630]	[149]	-8	hSpCas9	negative selection	11936521
17817836	17817859	17	-	28162770	MV411	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-3.527002748802094	[259]	[18]	-9	hSpCas9	negative selection	11936522
17816299	17816322	17	-	28162770	MV411	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-2.893043672767055	[193]	[21]	-9	hSpCas9	negative selection	11936523
17815941	17815964	17	-	28162770	MV411	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	0.495874580403611	[148]	[176]	4	hSpCas9	negative selection	11936524
17836786	17836809	17	+	28162770	MV411	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	-1.787050825602515	[126]	[30]	-8	hSpCas9	negative selection	11936525
17820462	17820485	17	+	28162770	MV411	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	0.671088180366327	[166]	[223]	6	hSpCas9	negative selection	11936526
17820131	17820154	17	+	28162770	MONOMAC1	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	-1.78199934778071	[2]	[0]	-8	hSpCas9	negative selection	12105883
17820368	17820391	17	+	28162770	MONOMAC1	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	0.5969114164469005	[138]	[240]	6	hSpCas9	negative selection	12105884
17820115	17820138	17	+	28162770	MONOMAC1	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	-0.23020371099475306	[87]	[85]	-2	hSpCas9	negative selection	12105885
17820089	17820112	17	+	28162770	MONOMAC1	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	1.1458508664634548	[163]	[415]	8	hSpCas9	negative selection	12105886
17819339	17819362	17	+	28162770	MONOMAC1	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	0.2094386387158662	[337]	[447]	2	hSpCas9	negative selection	12105887
17817836	17817859	17	-	28162770	MONOMAC1	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-3.6399803429082818	[173]	[15]	-9	hSpCas9	negative selection	12105888
17816299	17816322	17	-	28162770	MONOMAC1	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-0.3681487634523083	[151]	[134]	-3	hSpCas9	negative selection	12105889
17815941	17815964	17	-	28162770	MONOMAC1	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	0.4059595764918641	[105]	[160]	4	hSpCas9	negative selection	12105890
17836786	17836809	17	+	28162770	MONOMAC1	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	0.702658247144761	[66]	[124]	6	hSpCas9	negative selection	12105891
17820462	17820485	17	+	28162770	MONOMAC1	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	0.3932005957022766	[181]	[273]	4	hSpCas9	negative selection	12105892
17820131	17820154	17	+	28162770	OCIAML2	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	1.3367250968154427	[0]	[13]	9	hSpCas9	negative selection	12275249
17820368	17820391	17	+	28162770	OCIAML2	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-1.2662713267359749	[22]	[52]	-7	hSpCas9	negative selection	12275250
17820115	17820138	17	+	28162770	OCIAML2	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	-0.9812449845032363	[25]	[72]	-6	hSpCas9	negative selection	12275251
17820089	17820112	17	+	28162770	OCIAML2	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	-1.2802986131380119	[38]	[88]	-7	hSpCas9	negative selection	12275252
17819339	17819362	17	+	28162770	OCIAML2	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	-1.780969945854312	[123]	[199]	-8	hSpCas9	negative selection	12275253
17817836	17817859	17	-	28162770	OCIAML2	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-3.055592325963317	[59]	[39]	-9	hSpCas9	negative selection	12275254
17816299	17816322	17	-	28162770	OCIAML2	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-2.59616070732602	[35]	[32]	-8	hSpCas9	negative selection	12275255
17815941	17815964	17	-	28162770	OCIAML2	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	-0.30713109295928204	[24]	[111]	-3	hSpCas9	negative selection	12275256
17836786	17836809	17	+	28162770	OCIAML2	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	-0.34351790733882204	[18]	[82]	-3	hSpCas9	negative selection	12275257
17820462	17820485	17	+	28162770	OCIAML2	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	-1.136729088688723	[47]	[120]	-6	hSpCas9	negative selection	12275258
17820131	17820154	17	+	28162770	OCIAML3	viability	GGGGTGGAGCTGAACTGCGGTGG	SREBF1	ENSG00000072310	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12444615
17820368	17820391	17	+	28162770	OCIAML3	viability	GAGGAGCTCAATGTGGCAGGAGG	SREBF1	ENSG00000072310	-1.2189682089772382	[63]	[82]	-7	hSpCas9	negative selection	12444616
17820115	17820138	17	+	28162770	OCIAML3	viability	GGGGTAGCCTAACACAGGGGTGG	SREBF1	ENSG00000072310	1.2039485837311914	[21]	[152]	8	hSpCas9	negative selection	12444617
17820089	17820112	17	+	28162770	OCIAML3	viability	CCTGTAGAGAAGCCTCCCGGAGG	SREBF1	ENSG00000072310	0.830490188203747	[56]	[305]	7	hSpCas9	negative selection	12444618
17819339	17819362	17	+	28162770	OCIAML3	viability	ACAGTGGTGCCAGAGACCAGGGG	SREBF1	ENSG00000072310	0.20884026450686966	[228]	[798]	2	hSpCas9	negative selection	12444619
17817836	17817859	17	-	28162770	OCIAML3	viability	GGAGGGCGTGAAGACTGAGGTGG	SREBF1	ENSG00000072310	-1.5115454801321901	[67]	[71]	-8	hSpCas9	negative selection	12444620
17816299	17816322	17	-	28162770	OCIAML3	viability	GAACCTGGCAGAGTGTGCAGGGG	SREBF1	ENSG00000072310	-0.228723176242419	[58]	[151]	-2	hSpCas9	negative selection	12444621
17815941	17815964	17	-	28162770	OCIAML3	viability	GCAGTGGCTCTGCCACCCCGTGG	SREBF1	ENSG00000072310	0.36710334628224195	[46]	[182]	3	hSpCas9	negative selection	12444622
17836786	17836809	17	+	28162770	OCIAML3	viability	AAAGCCGCCTCGCTGAAGGGTGG	SREBF1	ENSG00000072310	-1.4829763279354193	[49]	[53]	-7	hSpCas9	negative selection	12444623
17820462	17820485	17	+	28162770	OCIAML3	viability	AGGGTGGGTCAAATAGGCCAGGG	SREBF1	ENSG00000072310	0.4118929611155212	[60]	[244]	4	hSpCas9	negative selection	12444624