Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:134957
• Symbol:STXBP5
• Description:syntaxin binding protein 5

DataSource: http://genomecrispr.dkfz.de/#!/results/STXBP5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
147204535	147204558	6	+	26472758	Jiyoye	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	0.33900387886429395	[64]	[61]	2	hSpCas9	negative selection	158623
147239186	147239209	6	-	26472758	Jiyoye	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	1.1930505761530261	[28]	[49]	7	hSpCas9	negative selection	158624
147262288	147262311	6	+	26472758	Jiyoye	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.6055040979518519	[94]	[108]	4	hSpCas9	negative selection	158625
147313996	147314019	6	+	26472758	Jiyoye	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	2.0625272101184278	[19]	[62]	8	hSpCas9	negative selection	158626
147314261	147314284	6	+	26472758	Jiyoye	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.4586036203128765	[247]	[256]	3	hSpCas9	negative selection	158627
147316258	147316281	6	+	26472758	Jiyoye	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-1.3477121206575955	[26]	[7]	-7	hSpCas9	negative selection	158628
147316337	147316360	6	-	26472758	Jiyoye	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-1.153230014971304	[232]	[78]	-7	hSpCas9	negative selection	158629
147373764	147373787	6	+	26472758	Jiyoye	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	-0.3297902126603327	[49]	[29]	-2	hSpCas9	negative selection	158630
147204557	147204580	6	+	26472758	Jiyoye	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	1.6051147591177826	[16]	[38]	8	hSpCas9	negative selection	158631
147205979	147206002	6	-	26472758	Jiyoye	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.7221076354390931	[139]	[63]	-5	hSpCas9	negative selection	158632
147204535	147204558	6	+	26472758	KBM7	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	0.9610153853705847	[229,213]	[147,252]	9	hSpCas9	negative selection	349741
147239186	147239209	6	-	26472758	KBM7	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	1.1188615743155823	[266,295]	[292,287]	9	hSpCas9	negative selection	349742
147262288	147262311	6	+	26472758	KBM7	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.630098107898688	[414,334]	[313,232]	7	hSpCas9	negative selection	349743
147313996	147314019	6	+	26472758	KBM7	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	0.7990573475457068	[152,156]	[106,145]	8	hSpCas9	negative selection	349744
147314261	147314284	6	+	26472758	KBM7	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.5617321267780891	[935,626]	[570,500]	6	hSpCas9	negative selection	349745
147316258	147316281	6	+	26472758	KBM7	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	0.2615671505080117	[24,21]	[8,16]	2	hSpCas9	negative selection	349746
147316337	147316360	6	-	26472758	KBM7	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-0.6768081882130934	[1212,1220]	[268,440]	-5	hSpCas9	negative selection	349747
147373764	147373787	6	+	26472758	KBM7	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	0.005533346123248961	[181,245]	[139,69]	0	hSpCas9	negative selection	349748
147204557	147204580	6	+	26472758	KBM7	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	0.8492427503535627	[221,114]	[104,168]	8	hSpCas9	negative selection	349749
147205979	147206002	6	-	26472758	KBM7	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.14937770202733977	[367,421]	[179,159]	-1	hSpCas9	negative selection	349750
147204535	147204558	6	+	26472758	Raji	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	-0.12965566192724975	[98]	[20]	-1	hSpCas9	negative selection	540859
147239186	147239209	6	-	26472758	Raji	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	-0.24311371171053375	[101]	[19]	-2	hSpCas9	negative selection	540860
147262288	147262311	6	+	26472758	Raji	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.41932754168833986	[144]	[44]	4	hSpCas9	negative selection	540861
147313996	147314019	6	+	26472758	Raji	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	1.4520317067610455	[62]	[39]	9	hSpCas9	negative selection	540862
147314261	147314284	6	+	26472758	Raji	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.20983080434441703	[461]	[123]	2	hSpCas9	negative selection	540863
147316258	147316281	6	+	26472758	Raji	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-1.7995070602349195	[14]	[0]	-8	hSpCas9	negative selection	540864
147316337	147316360	6	-	26472758	Raji	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-1.6009613808528387	[548]	[41]	-8	hSpCas9	negative selection	540865
147373764	147373787	6	+	26472758	Raji	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	0.5466685808991203	[58]	[19]	5	hSpCas9	negative selection	540866
147204557	147204580	6	+	26472758	Raji	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	0.2092631493928132	[81]	[21]	2	hSpCas9	negative selection	540867
147205979	147206002	6	-	26472758	Raji	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.5073263087416087	[244]	[39]	-4	hSpCas9	negative selection	540868
147204535	147204558	6	+	26472758	K562	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	1.1806036300690037	[207]	[397]	8	hSpCas9	negative selection	731977
147239186	147239209	6	-	26472758	K562	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	0.0351907655284468	[199]	[172]	0	hSpCas9	negative selection	731978
147262288	147262311	6	+	26472758	K562	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.671660366532417	[205]	[276]	5	hSpCas9	negative selection	731979
147313996	147314019	6	+	26472758	K562	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	0.31612019302063543	[156]	[164]	2	hSpCas9	negative selection	731980
147314261	147314284	6	+	26472758	K562	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	1.3105887647768226	[798]	[1672]	9	hSpCas9	negative selection	731981
147316258	147316281	6	+	26472758	K562	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-0.8467291603917482	[48]	[22]	-5	hSpCas9	negative selection	731982
147316337	147316360	6	-	26472758	K562	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-1.6019849208128358	[1085]	[301]	-7	hSpCas9	negative selection	731983
147373764	147373787	6	+	26472758	K562	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	-0.6624718679420716	[134]	[71]	-4	hSpCas9	negative selection	731984
147204557	147204580	6	+	26472758	K562	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	1.1733356296049644	[103]	[197]	8	hSpCas9	negative selection	731985
147205979	147206002	6	-	26472758	K562	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.6291329370926141	[261]	[142]	-4	hSpCas9	negative selection	731986
147204609	147204632	6	+	26627737	DLD1	viability	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.2368576768646673	[821]	[199,207,241]	-2	hSpCas9	negative selection	830855
147205962	147205985	6	+	26627737	DLD1	viability	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	-0.1731408458379846	[764]	[137,267,229]	-2	hSpCas9	negative selection	830856
147235307	147235330	6	-	26627737	DLD1	viability	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	0.30630895767426236	[357]	[88,140,178]	3	hSpCas9	negative selection	830857
147260652	147260675	6	+	26627737	DLD1	viability	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.2848308764398437	[2609]	[1010,1039,940]	3	hSpCas9	negative selection	830858
147262332	147262355	6	+	26627737	DLD1	viability	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.31915163349925935	[251]	[126,76,90]	3	hSpCas9	negative selection	830859
147278086	147278109	6	-	26627737	DLD1	viability	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	1.075304090734901	[314]	[95,331,200]	8	hSpCas9	negative selection	830860
147204609	147204632	6	+	26627737	GBM cells	viability after 5 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.3438164344930195	[380]	[140,180]	-5	hSpCas9	negative selection	913170
147205962	147205985	6	+	26627737	GBM cells	viability after 5 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	-0.3919873243810522	[344]	[152,128]	-6	hSpCas9	negative selection	913171
147235307	147235330	6	-	26627737	GBM cells	viability after 5 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	0.3245829258944164	[168]	[88,137]	5	hSpCas9	negative selection	913172
147260652	147260675	6	+	26627737	GBM cells	viability after 5 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.05669270683489458	[1046]	[614,552]	0	hSpCas9	negative selection	913173
147262332	147262355	6	+	26627737	GBM cells	viability after 5 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.3622205832577816	[168]	[121,110]	5	hSpCas9	negative selection	913174
147278086	147278109	6	-	26627737	GBM cells	viability after 5 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.5571253576374804	[255]	[247,155]	7	hSpCas9	negative selection	913175
147204609	147204632	6	+	26627737	GBM cells	viability after 13 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.26453940234594436	[380]	[213,137]	-3	hSpCas9	negative selection	995485
147205962	147205985	6	+	26627737	GBM cells	viability after 13 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	-0.7304252643192926	[344]	[103,119]	-7	hSpCas9	negative selection	995486
147235307	147235330	6	-	26627737	GBM cells	viability after 13 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	0.1665908707004487	[168]	[151,62]	2	hSpCas9	negative selection	995487
147260652	147260675	6	+	26627737	GBM cells	viability after 13 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	-0.16169650506547617	[1046]	[546,475]	-2	hSpCas9	negative selection	995488
147262332	147262355	6	+	26627737	GBM cells	viability after 13 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.7426964280946966	[168]	[196,117]	8	hSpCas9	negative selection	995489
147278086	147278109	6	-	26627737	GBM cells	viability after 13 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.9856609298600726	[255]	[311,244]	9	hSpCas9	negative selection	995490
147204609	147204632	6	+	26627737	GBM cells	viability after 21 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.0659205348083467	[380]	[191,202]	0	hSpCas9	negative selection	1077800
147205962	147205985	6	+	26627737	GBM cells	viability after 21 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	-0.5411060180965641	[344]	[144,113]	-5	hSpCas9	negative selection	1077801
147235307	147235330	6	-	26627737	GBM cells	viability after 21 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	0.7084931171105071	[168]	[160,139]	7	hSpCas9	negative selection	1077802
147260652	147260675	6	+	26627737	GBM cells	viability after 21 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.20674110114800648	[1046]	[680,633]	2	hSpCas9	negative selection	1077803
147262332	147262355	6	+	26627737	GBM cells	viability after 21 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	1.001521237318734	[168]	[187,179]	8	hSpCas9	negative selection	1077804
147278086	147278109	6	-	26627737	GBM cells	viability after 21 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.23553544881351135	[255]	[157,168]	2	hSpCas9	negative selection	1077805
147204609	147204632	6	+	26627737	RPE1	viability after 9 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.6491559436682344	[1231]	[279,201]	-5	hSpCas9	negative selection	1160115
147205962	147205985	6	+	26627737	RPE1	viability after 9 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	3.964960596042066	[61]	[203,430]	9	hSpCas9	negative selection	1160116
147235307	147235330	6	-	26627737	RPE1	viability after 9 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	-0.7299075615079906	[1113]	[163,269]	-5	hSpCas9	negative selection	1160117
147260652	147260675	6	+	26627737	RPE1	viability after 9 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.4529697050620154	[3530]	[1083,2066]	3	hSpCas9	negative selection	1160118
147262332	147262355	6	+	26627737	RPE1	viability after 9 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.07174538101852956	[381]	[126,123]	0	hSpCas9	negative selection	1160119
147278086	147278109	6	-	26627737	RPE1	viability after 9 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	1.0355634784990573	[910]	[223,1049]	6	hSpCas9	negative selection	1160120
147204609	147204632	6	+	26627737	RPE1	viability after 12 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.16680279565611356	[1231]	[238,353]	-1	hSpCas9	negative selection	1242430
147205962	147205985	6	+	26627737	RPE1	viability after 12 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	3.4589657777222635	[61]	[137,230]	9	hSpCas9	negative selection	1242431
147235307	147235330	6	-	26627737	RPE1	viability after 12 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	-0.8975807910710565	[1113]	[165,154]	-6	hSpCas9	negative selection	1242432
147260652	147260675	6	+	26627737	RPE1	viability after 12 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.4207981729499637	[3530]	[1233,1307]	3	hSpCas9	negative selection	1242433
147262332	147262355	6	+	26627737	RPE1	viability after 12 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.2310587183296373	[381]	[101,139]	1	hSpCas9	negative selection	1242434
147278086	147278109	6	-	26627737	RPE1	viability after 12 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	1.3180776340172873	[910]	[312,924]	7	hSpCas9	negative selection	1242435
147204609	147204632	6	+	26627737	RPE1	viability after 15 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.08071481072935671	[1231]	[298,358]	0	hSpCas9	negative selection	1324745
147205962	147205985	6	+	26627737	RPE1	viability after 15 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	4.009197385198405	[61]	[174,385]	9	hSpCas9	negative selection	1324746
147235307	147235330	6	-	26627737	RPE1	viability after 15 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	-0.29916002565341604	[1113]	[277,234]	-2	hSpCas9	negative selection	1324747
147260652	147260675	6	+	26627737	RPE1	viability after 15 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.3866419935623453	[3530]	[1258,1350]	2	hSpCas9	negative selection	1324748
147262332	147262355	6	+	26627737	RPE1	viability after 15 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	-1.0203268686824403	[381]	[65,40]	-6	hSpCas9	negative selection	1324749
147278086	147278109	6	-	26627737	RPE1	viability after 15 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	1.7273026699372918	[910]	[162,1518]	8	hSpCas9	negative selection	1324750
147204609	147204632	6	+	26627737	RPE1	viability after 18 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	0.1080338027593426	[1231]	[367,347]	0	hSpCas9	negative selection	1407060
147205962	147205985	6	+	26627737	RPE1	viability after 18 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	4.134748879505635	[61]	[174,420]	9	hSpCas9	negative selection	1407061
147235307	147235330	6	-	26627737	RPE1	viability after 18 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	-0.5321817978403545	[1113]	[160,257]	-3	hSpCas9	negative selection	1407062
147260652	147260675	6	+	26627737	RPE1	viability after 18 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.23508507305954796	[3530]	[918,1337]	1	hSpCas9	negative selection	1407063
147262332	147262355	6	+	26627737	RPE1	viability after 18 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.27660083249585043	[381]	[164,81]	1	hSpCas9	negative selection	1407064
147278086	147278109	6	-	26627737	RPE1	viability after 18 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	1.6504548807772492	[910]	[226,1353]	8	hSpCas9	negative selection	1407065
147204609	147204632	6	+	26627737	HeLa	viability after 8 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.038708941303190025	[582]	[375,215,181]	0	hSpCas9	negative selection	1489375
147205962	147205985	6	+	26627737	HeLa	viability after 8 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	1.2162054241743454	[289]	[422,293,197]	8	hSpCas9	negative selection	1489376
147235307	147235330	6	-	26627737	HeLa	viability after 8 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	1.1805617369506538	[225]	[247,273,156]	8	hSpCas9	negative selection	1489377
147260652	147260675	6	+	26627737	HeLa	viability after 8 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.8680233022690922	[983]	[934,850,604]	7	hSpCas9	negative selection	1489378
147262332	147262355	6	+	26627737	HeLa	viability after 8 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.4496978650134362	[77]	[68,27,46]	4	hSpCas9	negative selection	1489379
147278086	147278109	6	-	26627737	HeLa	viability after 8 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	-0.4040584446452545	[708]	[215,280,200]	-4	hSpCas9	negative selection	1489380
147204609	147204632	6	+	26627737	HeLa	viability after 12 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	0.1725962522207608	[582]	[93,464,229]	1	hSpCas9	negative selection	1571690
147205962	147205985	6	+	26627737	HeLa	viability after 12 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	1.1939645590996375	[289]	[312,308,197]	8	hSpCas9	negative selection	1571691
147235307	147235330	6	-	26627737	HeLa	viability after 12 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	0.42225928663248813	[225]	[118,108,148]	3	hSpCas9	negative selection	1571692
147260652	147260675	6	+	26627737	HeLa	viability after 12 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	1.2470316064421627	[983]	[1110,774,1033]	8	hSpCas9	negative selection	1571693
147262332	147262355	6	+	26627737	HeLa	viability after 12 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	1.2468681759063083	[77]	[47,63,117]	8	hSpCas9	negative selection	1571694
147278086	147278109	6	-	26627737	HeLa	viability after 12 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	-1.2931714498526095	[708]	[118,106,133]	-8	hSpCas9	negative selection	1571695
147204609	147204632	6	+	26627737	HeLa	viability after 15 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.22910002349110048	[582]	[162,193,254]	-2	hSpCas9	negative selection	1654005
147205962	147205985	6	+	26627737	HeLa	viability after 15 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	1.0824840056717844	[289]	[288,216,242]	7	hSpCas9	negative selection	1654006
147235307	147235330	6	-	26627737	HeLa	viability after 15 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	0.6175654504796511	[225]	[73,140,214]	5	hSpCas9	negative selection	1654007
147260652	147260675	6	+	26627737	HeLa	viability after 15 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.9771406072465509	[983]	[771,804,788]	7	hSpCas9	negative selection	1654008
147262332	147262355	6	+	26627737	HeLa	viability after 15 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	1.702086780662734	[77]	[128,108,68]	9	hSpCas9	negative selection	1654009
147278086	147278109	6	-	26627737	HeLa	viability after 15 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	-0.8950284506955564	[708]	[128,120,220]	-7	hSpCas9	negative selection	1654010
147204609	147204632	6	+	26627737	HeLa	viability after 18 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.16981555188667674	[582]	[123,162,254]	-1	hSpCas9	negative selection	1736320
147205962	147205985	6	+	26627737	HeLa	viability after 18 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	1.0964925544886892	[289]	[195,182,242]	7	hSpCas9	negative selection	1736321
147235307	147235330	6	-	26627737	HeLa	viability after 18 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	0.6120227978113567	[225]	[49,114,214]	5	hSpCas9	negative selection	1736322
147260652	147260675	6	+	26627737	HeLa	viability after 18 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.9659657985256092	[983]	[508,662,788]	7	hSpCas9	negative selection	1736323
147262332	147262355	6	+	26627737	HeLa	viability after 18 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	1.7489917705103215	[77]	[90,92,68]	9	hSpCas9	negative selection	1736324
147278086	147278109	6	-	26627737	HeLa	viability after 18 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	-0.8596628300837148	[708]	[90,103,220]	-6	hSpCas9	negative selection	1736325
147204609	147204632	6	+	26627737	HCT116	viability after 6 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	1.8459509813516726	[598]	[547,222]	8	hSpCas9	negative selection	1818635
147205962	147205985	6	+	26627737	HCT116	viability after 6 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	2.187495569998919	[338]	[225,251]	9	hSpCas9	negative selection	1818636
147235307	147235330	6	-	26627737	HCT116	viability after 6 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	-0.36855755010078284	[513]	[137,20]	-2	hSpCas9	negative selection	1818637
147260652	147260675	6	+	26627737	HCT116	viability after 6 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.8770482703635023	[2391]	[582,749]	5	hSpCas9	negative selection	1818638
147262332	147262355	6	+	26627737	HCT116	viability after 6 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	-2.0130092859134967	[306]	[0,17]	-8	hSpCas9	negative selection	1818639
147278086	147278109	6	-	26627737	HCT116	viability after 6 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	2.1628641349503748	[505]	[138,475]	9	hSpCas9	negative selection	1818640
147204609	147204632	6	+	26627737	HCT116	viability after 8 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.17683020513159464	[521]	[267,190,303]	-2	hSpCas9	negative selection	1900950
147205962	147205985	6	+	26627737	HCT116	viability after 8 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	-0.5033680398400767	[278]	[206,83,36]	-5	hSpCas9	negative selection	1900951
147235307	147235330	6	-	26627737	HCT116	viability after 8 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	-0.33985935307883464	[283]	[152,138,79]	-4	hSpCas9	negative selection	1900952
147260652	147260675	6	+	26627737	HCT116	viability after 8 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.5759441495316191	[937]	[778,799,732]	6	hSpCas9	negative selection	1900953
147262332	147262355	6	+	26627737	HCT116	viability after 8 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.14672651486989718	[158]	[89,115,84]	1	hSpCas9	negative selection	1900954
147278086	147278109	6	-	26627737	HCT116	viability after 8 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.07827377703868402	[336]	[94,266,223]	0	hSpCas9	negative selection	1900955
147204609	147204632	6	+	26627737	HCT116	viability after 9 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	1.0414692087360122	[598]	[350,311]	7	hSpCas9	negative selection	1983265
147205962	147205985	6	+	26627737	HCT116	viability after 9 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	2.408335638900646	[338]	[608,378]	9	hSpCas9	negative selection	1983266
147235307	147235330	6	-	26627737	HCT116	viability after 9 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	-1.204397804842033	[513]	[120,10]	-7	hSpCas9	negative selection	1983267
147260652	147260675	6	+	26627737	HCT116	viability after 9 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.4686995478163547	[2391]	[822,931]	3	hSpCas9	negative selection	1983268
147262332	147262355	6	+	26627737	HCT116	viability after 9 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	-1.0177364911869098	[306]	[11,62]	-6	hSpCas9	negative selection	1983269
147278086	147278109	6	-	26627737	HCT116	viability after 9 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.13819588841895084	[505]	[122,168]	1	hSpCas9	negative selection	1983270
147204609	147204632	6	+	26627737	HCT116	viability after 12 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.5251725760167204	[521]	[226,162,177]	-5	hSpCas9	negative selection	2065580
147205962	147205985	6	+	26627737	HCT116	viability after 12 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	-0.06945111748242494	[278]	[159,163,93]	0	hSpCas9	negative selection	2065581
147235307	147235330	6	-	26627737	HCT116	viability after 12 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	0.058156527041136205	[283]	[76,276,121]	0	hSpCas9	negative selection	2065582
147260652	147260675	6	+	26627737	HCT116	viability after 12 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.42288084482176536	[937]	[625,677,681]	4	hSpCas9	negative selection	2065583
147262332	147262355	6	+	26627737	HCT116	viability after 12 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.21581869532784792	[158]	[66,147,79]	2	hSpCas9	negative selection	2065584
147278086	147278109	6	-	26627737	HCT116	viability after 12 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.11560703583563425	[336]	[204,171,196]	1	hSpCas9	negative selection	2065585
147204609	147204632	6	+	26627737	HCT116	viability after 15 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.11751693474308	[521]	[388,118,333]	-1	hSpCas9	negative selection	2147895
147205962	147205985	6	+	26627737	HCT116	viability after 15 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	0.34957327897916435	[278]	[296,223,103]	3	hSpCas9	negative selection	2147896
147235307	147235330	6	-	26627737	HCT116	viability after 15 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	-0.2939150581601056	[283]	[133,195,69]	-3	hSpCas9	negative selection	2147897
147260652	147260675	6	+	26627737	HCT116	viability after 15 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.6197063204913509	[937]	[998,840,665]	5	hSpCas9	negative selection	2147898
147262332	147262355	6	+	26627737	HCT116	viability after 15 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	-0.32193589642066855	[158]	[111,47,63]	-3	hSpCas9	negative selection	2147899
147278086	147278109	6	-	26627737	HCT116	viability after 15 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	-0.06081979013740661	[336]	[178,120,254]	0	hSpCas9	negative selection	2147900
147204609	147204632	6	+	26627737	HCT116	viability after 18 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	0.10553992644182353	[521]	[215,161,451]	0	hSpCas9	negative selection	2230210
147205962	147205985	6	+	26627737	HCT116	viability after 18 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	0.9609591744389655	[278]	[199,336,244]	7	hSpCas9	negative selection	2230211
147235307	147235330	6	-	26627737	HCT116	viability after 18 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	-0.2949313552106951	[283]	[115,167,44]	-3	hSpCas9	negative selection	2230212
147260652	147260675	6	+	26627737	HCT116	viability after 18 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.3534260548721635	[937]	[605,551,581]	3	hSpCas9	negative selection	2230213
147262332	147262355	6	+	26627737	HCT116	viability after 18 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.4392976715699162	[158]	[85,168,50]	4	hSpCas9	negative selection	2230214
147278086	147278109	6	-	26627737	HCT116	viability after 18 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.2929224015916488	[336]	[155,172,274]	2	hSpCas9	negative selection	2230215
147248189	147248212	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAATTGCTTGAACCCAGGAAG	STXBP5	ENSG00000164506	0.059142044687262585	[6,100]	[1,23]	0	dCas9-VP64	positive selection	2407322
147270185	147270208	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGATCGAGACCATCCTAG	STXBP5	ENSG00000164506	-0.5760906316419423	[119,210]	[24,22]	-3	dCas9-VP64	positive selection	2418433
147287411	147287434	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGATCGAGACCATCCCGG	STXBP5	ENSG00000164506	-0.5760906316419423	[119,210]	[24,22]	-3	dCas9-VP64	positive selection	2418468
147248189	147248212	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAATTGCTTGAACCCAGGAAG	STXBP5	ENSG00000164506	0.5790361197083687	[35,47]	[19,19]	4	dCas9-VP64	positive selection	2502577
147270185	147270208	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGATCGAGACCATCCTAG	STXBP5	ENSG00000164506	-0.5911896850137947	[183,271]	[71,26]	-6	dCas9-VP64	positive selection	2513688
147287411	147287434	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGATCGAGACCATCCCGG	STXBP5	ENSG00000164506	-0.5911896850137947	[183,271]	[71,26]	-6	dCas9-VP64	positive selection	2513723
147204568	147204591	6	+	27260157	DLD1	viability	CCTGACCGCCGGCTCGTCCTCGG	STXBP5	ENSG00000164506	-0.223034722785328	[]	[]	-2	hSpCas9	negative selection	2573854
147262336	147262359	6	-	27260157	DLD1	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.50291981897036	[]	[]	8	hSpCas9	negative selection	2574339
147260652	147260675	6	+	27260157	DLD1	viability	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.0566898872749306	[]	[]	3	hSpCas9	negative selection	2577738
147204557	147204580	6	+	27260157	DLD1	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	0.336955175457412	[]	[]	4	hSpCas9	negative selection	2581006
147205989	147206012	6	-	27260157	DLD1	viability	GCCAGGGCTGAGGGTTGATAGGG	STXBP5	ENSG00000164506	0.526202199360614	[]	[]	8	hSpCas9	negative selection	2581658
147278136	147278159	6	+	27260157	DLD1	viability	CAGATGGCACCTTGACTATATGG	STXBP5	ENSG00000164506	0.1677661904336	[]	[]	3	hSpCas9	negative selection	2582171
147204616	147204639	6	+	27260157	DLD1	viability	TCCGCCTGGGAACCGGGAGCCGG	STXBP5	ENSG00000164506	-1.20696554974193	[]	[]	-7	hSpCas9	negative selection	2585173
147315649	147315672	6	+	27260157	DLD1	viability	AGTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	-2.07376570759885	[]	[]	-8	hSpCas9	negative selection	2585545
147313963	147313986	6	-	27260157	DLD1	viability	AGTGCAGGAATAAGGTCCACAGG	STXBP5	ENSG00000164506	0.473776973936005	[]	[]	8	hSpCas9	negative selection	2587508
147206019	147206042	6	-	27260157	DLD1	viability	ACTGCCAGGATCTTCTGTACAGG	STXBP5	ENSG00000164506	0.34927399400754	[]	[]	4	hSpCas9	negative selection	2609741
147205988	147206011	6	+	27260157	DLD1	viability	TCCCTATCAACCCTCAGCCCTGG	STXBP5	ENSG00000164506	-0.554891485817975	[]	[]	-4	hSpCas9	negative selection	2610003
147204643	147204666	6	-	27260157	DLD1	viability	GCTCGGACTGGAGCGTTTCCTGG	STXBP5	ENSG00000164506	-0.0936101872209789	[]	[]	0	hSpCas9	negative selection	2610144
147260639	147260662	6	-	27260157	DLD1	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.575477031198388	[]	[]	8	hSpCas9	negative selection	2613332
147324969	147324992	6	+	27260157	DLD1	viability	TCACCACTTAAACAGTCTCCAGG	STXBP5	ENSG00000164506	0.165794370537057	[]	[]	3	hSpCas9	negative selection	2615789
147262305	147262328	6	-	27260157	DLD1	viability	TTATATGGACCACAGGTCCTGGG	STXBP5	ENSG00000164506	0.244615592280706	[]	[]	4	hSpCas9	negative selection	2616948
147235280	147235303	6	-	27260157	DLD1	viability	CTGCAGCTCCACTGTCATGCTGG	STXBP5	ENSG00000164506	0.523155597218953	[]	[]	8	hSpCas9	negative selection	2643196
147315617	147315640	6	+	27260157	DLD1	viability	ATGCCATTCAGATCATCTCCTGG	STXBP5	ENSG00000164506	0.621740192324849	[]	[]	8	hSpCas9	negative selection	2644738
147314261	147314284	6	+	27260157	DLD1	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	-0.602337486379687	[]	[]	-5	hSpCas9	negative selection	2645030
147260639	147260662	6	+	27260157	DLD1	viability	CCAGAGTAAGTGGCTCTATGTGG	STXBP5	ENSG00000164506	0.0312758533920933	[]	[]	0	hSpCas9	negative selection	2645092
147316301	147316324	6	-	27260157	DLD1	viability	TTGGACCCTCCCACGGGTGTTGG	STXBP5	ENSG00000164506	0.655328161713627	[]	[]	8	hSpCas9	negative selection	2646684
147204568	147204591	6	+	27260157	HT1080	viability	CCTGACCGCCGGCTCGTCCTCGG	STXBP5	ENSG00000164506	-0.313408400282031	[]	[]	-7	hSpCas9	negative selection	2649984
147262336	147262359	6	-	27260157	HT1080	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	-0.115103999146478	[]	[]	0	hSpCas9	negative selection	2650469
147260652	147260675	6	+	27260157	HT1080	viability	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	-0.224740384376169	[]	[]	0	hSpCas9	negative selection	2653868
147204557	147204580	6	+	27260157	HT1080	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	0.140629926538499	[]	[]	1	hSpCas9	negative selection	2657136
147205989	147206012	6	-	27260157	HT1080	viability	GCCAGGGCTGAGGGTTGATAGGG	STXBP5	ENSG00000164506	-0.395277688502571	[]	[]	-7	hSpCas9	negative selection	2657788
147278136	147278159	6	+	27260157	HT1080	viability	CAGATGGCACCTTGACTATATGG	STXBP5	ENSG00000164506	0.70762414961529	[]	[]	6	hSpCas9	negative selection	2658301
147204616	147204639	6	+	27260157	HT1080	viability	TCCGCCTGGGAACCGGGAGCCGG	STXBP5	ENSG00000164506	-0.778139179635636	[]	[]	-8	hSpCas9	negative selection	2661303
147315649	147315672	6	+	27260157	HT1080	viability	AGTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	-0.572180830096146	[]	[]	-7	hSpCas9	negative selection	2661675
147313963	147313986	6	-	27260157	HT1080	viability	AGTGCAGGAATAAGGTCCACAGG	STXBP5	ENSG00000164506	0.351536854230972	[]	[]	3	hSpCas9	negative selection	2663638
147206019	147206042	6	-	27260157	HT1080	viability	ACTGCCAGGATCTTCTGTACAGG	STXBP5	ENSG00000164506	0.489444802523589	[]	[]	4	hSpCas9	negative selection	2685871
147205988	147206011	6	+	27260157	HT1080	viability	TCCCTATCAACCCTCAGCCCTGG	STXBP5	ENSG00000164506	0.499171570128962	[]	[]	4	hSpCas9	negative selection	2686133
147204643	147204666	6	-	27260157	HT1080	viability	GCTCGGACTGGAGCGTTTCCTGG	STXBP5	ENSG00000164506	0.511662715792802	[]	[]	4	hSpCas9	negative selection	2686274
147260639	147260662	6	-	27260157	HT1080	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	1.08761959087111	[]	[]	8	hSpCas9	negative selection	2689462
147324969	147324992	6	+	27260157	HT1080	viability	TCACCACTTAAACAGTCTCCAGG	STXBP5	ENSG00000164506	0.462006831150152	[]	[]	4	hSpCas9	negative selection	2691919
147262305	147262328	6	-	27260157	HT1080	viability	TTATATGGACCACAGGTCCTGGG	STXBP5	ENSG00000164506	0.445957016595147	[]	[]	4	hSpCas9	negative selection	2693078
147235280	147235303	6	-	27260157	HT1080	viability	CTGCAGCTCCACTGTCATGCTGG	STXBP5	ENSG00000164506	0.331776242856432	[]	[]	3	hSpCas9	negative selection	2719326
147315617	147315640	6	+	27260157	HT1080	viability	ATGCCATTCAGATCATCTCCTGG	STXBP5	ENSG00000164506	0.964968335295419	[]	[]	7	hSpCas9	negative selection	2720868
147314261	147314284	6	+	27260157	HT1080	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.538752081826129	[]	[]	5	hSpCas9	negative selection	2721160
147260639	147260662	6	+	27260157	HT1080	viability	CCAGAGTAAGTGGCTCTATGTGG	STXBP5	ENSG00000164506	-0.329465829606709	[]	[]	-7	hSpCas9	negative selection	2721222
147316301	147316324	6	-	27260157	HT1080	viability	TTGGACCCTCCCACGGGTGTTGG	STXBP5	ENSG00000164506	0.228814476070337	[]	[]	2	hSpCas9	negative selection	2722814
147204568	147204591	6	+	27260157	MKN45	viability	CCTGACCGCCGGCTCGTCCTCGG	STXBP5	ENSG00000164506	0.80610049921824	[]	[]	7	hSpCas9	negative selection	2726114
147262336	147262359	6	-	27260157	MKN45	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	-0.955878699740688	[]	[]	-7	hSpCas9	negative selection	2726599
147260652	147260675	6	+	27260157	MKN45	viability	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	-0.764703156165391	[]	[]	-7	hSpCas9	negative selection	2729998
147204557	147204580	6	+	27260157	MKN45	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	1.0837400146273	[]	[]	8	hSpCas9	negative selection	2733266
147205989	147206012	6	-	27260157	MKN45	viability	GCCAGGGCTGAGGGTTGATAGGG	STXBP5	ENSG00000164506	-0.0659276260555388	[]	[]	0	hSpCas9	negative selection	2733918
147278136	147278159	6	+	27260157	MKN45	viability	CAGATGGCACCTTGACTATATGG	STXBP5	ENSG00000164506	0.179071608968855	[]	[]	5	hSpCas9	negative selection	2734431
147204616	147204639	6	+	27260157	MKN45	viability	TCCGCCTGGGAACCGGGAGCCGG	STXBP5	ENSG00000164506	-1.60678931566365	[]	[]	-9	hSpCas9	negative selection	2737433
147315649	147315672	6	+	27260157	MKN45	viability	AGTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	-1.04629561323085	[]	[]	-8	hSpCas9	negative selection	2737805
147313963	147313986	6	-	27260157	MKN45	viability	AGTGCAGGAATAAGGTCCACAGG	STXBP5	ENSG00000164506	0.261037248827497	[]	[]	5	hSpCas9	negative selection	2739768
147206019	147206042	6	-	27260157	MKN45	viability	ACTGCCAGGATCTTCTGTACAGG	STXBP5	ENSG00000164506	0.927656073616494	[]	[]	8	hSpCas9	negative selection	2762001
147205988	147206011	6	+	27260157	MKN45	viability	TCCCTATCAACCCTCAGCCCTGG	STXBP5	ENSG00000164506	0.218237496483682	[]	[]	5	hSpCas9	negative selection	2762263
147204643	147204666	6	-	27260157	MKN45	viability	GCTCGGACTGGAGCGTTTCCTGG	STXBP5	ENSG00000164506	-0.366981904762365	[]	[]	-1	hSpCas9	negative selection	2762404
147260639	147260662	6	-	27260157	MKN45	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.316905183839399	[]	[]	5	hSpCas9	negative selection	2765592
147324969	147324992	6	+	27260157	MKN45	viability	TCACCACTTAAACAGTCTCCAGG	STXBP5	ENSG00000164506	0.292087725145542	[]	[]	5	hSpCas9	negative selection	2768049
147262305	147262328	6	-	27260157	MKN45	viability	TTATATGGACCACAGGTCCTGGG	STXBP5	ENSG00000164506	0.222642199995806	[]	[]	5	hSpCas9	negative selection	2769208
147235280	147235303	6	-	27260157	MKN45	viability	CTGCAGCTCCACTGTCATGCTGG	STXBP5	ENSG00000164506	0.692345425147034	[]	[]	7	hSpCas9	negative selection	2795456
147315617	147315640	6	+	27260157	MKN45	viability	ATGCCATTCAGATCATCTCCTGG	STXBP5	ENSG00000164506	0.000927798977624963	[]	[]	0	hSpCas9	negative selection	2796998
147314261	147314284	6	+	27260157	MKN45	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.301641200141442	[]	[]	5	hSpCas9	negative selection	2797290
147260639	147260662	6	+	27260157	MKN45	viability	CCAGAGTAAGTGGCTCTATGTGG	STXBP5	ENSG00000164506	-0.132892945917848	[]	[]	0	hSpCas9	negative selection	2797352
147316301	147316324	6	-	27260157	MKN45	viability	TTGGACCCTCCCACGGGTGTTGG	STXBP5	ENSG00000164506	0.535848225789393	[]	[]	6	hSpCas9	negative selection	2798944
147204568	147204591	6	+	27260157	RKO	viability	CCTGACCGCCGGCTCGTCCTCGG	STXBP5	ENSG00000164506	-0.64996151890551	[]	[]	-7	hSpCas9	negative selection	2802244
147262336	147262359	6	-	27260157	RKO	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.595294547937793	[]	[]	3	hSpCas9	negative selection	2802729
147260652	147260675	6	+	27260157	RKO	viability	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	-0.830833540183121	[]	[]	-7	hSpCas9	negative selection	2806128
147204557	147204580	6	+	27260157	RKO	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	0.936934894340197	[]	[]	8	hSpCas9	negative selection	2809396
147205989	147206012	6	-	27260157	RKO	viability	GCCAGGGCTGAGGGTTGATAGGG	STXBP5	ENSG00000164506	-0.0229525885236517	[]	[]	0	hSpCas9	negative selection	2810048
147278136	147278159	6	+	27260157	RKO	viability	CAGATGGCACCTTGACTATATGG	STXBP5	ENSG00000164506	0.0625856248203003	[]	[]	0	hSpCas9	negative selection	2810561
147204616	147204639	6	+	27260157	RKO	viability	TCCGCCTGGGAACCGGGAGCCGG	STXBP5	ENSG00000164506	-2.29489481246047	[]	[]	-9	hSpCas9	negative selection	2813563
147315649	147315672	6	+	27260157	RKO	viability	AGTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	0.736956867727393	[]	[]	8	hSpCas9	negative selection	2813935
147313963	147313986	6	-	27260157	RKO	viability	AGTGCAGGAATAAGGTCCACAGG	STXBP5	ENSG00000164506	0.697292743811191	[]	[]	8	hSpCas9	negative selection	2815898
147206019	147206042	6	-	27260157	RKO	viability	ACTGCCAGGATCTTCTGTACAGG	STXBP5	ENSG00000164506	0.733950194373068	[]	[]	8	hSpCas9	negative selection	2838131
147205988	147206011	6	+	27260157	RKO	viability	TCCCTATCAACCCTCAGCCCTGG	STXBP5	ENSG00000164506	-0.476057859780684	[]	[]	-6	hSpCas9	negative selection	2838393
147204643	147204666	6	-	27260157	RKO	viability	GCTCGGACTGGAGCGTTTCCTGG	STXBP5	ENSG00000164506	0.492850893080893	[]	[]	2	hSpCas9	negative selection	2838534
147260639	147260662	6	-	27260157	RKO	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.84962971255061	[]	[]	8	hSpCas9	negative selection	2841722
147324969	147324992	6	+	27260157	RKO	viability	TCACCACTTAAACAGTCTCCAGG	STXBP5	ENSG00000164506	-0.220879330102611	[]	[]	-1	hSpCas9	negative selection	2844179
147262305	147262328	6	-	27260157	RKO	viability	TTATATGGACCACAGGTCCTGGG	STXBP5	ENSG00000164506	0.290689366105689	[]	[]	1	hSpCas9	negative selection	2845338
147235280	147235303	6	-	27260157	RKO	viability	CTGCAGCTCCACTGTCATGCTGG	STXBP5	ENSG00000164506	0.425404132301133	[]	[]	2	hSpCas9	negative selection	2871586
147315617	147315640	6	+	27260157	RKO	viability	ATGCCATTCAGATCATCTCCTGG	STXBP5	ENSG00000164506	0.648447532525687	[]	[]	3	hSpCas9	negative selection	2873128
147314261	147314284	6	+	27260157	RKO	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	-0.115782840835133	[]	[]	0	hSpCas9	negative selection	2873420
147260639	147260662	6	+	27260157	RKO	viability	CCAGAGTAAGTGGCTCTATGTGG	STXBP5	ENSG00000164506	0.336880105251226	[]	[]	1	hSpCas9	negative selection	2873482
147316301	147316324	6	-	27260157	RKO	viability	TTGGACCCTCCCACGGGTGTTGG	STXBP5	ENSG00000164506	0.62144461414425	[]	[]	3	hSpCas9	negative selection	2875074
147204568	147204591	6	+	27260157	SF268	viability	CCTGACCGCCGGCTCGTCCTCGG	STXBP5	ENSG00000164506	0.768220573418331	[]	[]	8	hSpCas9	negative selection	2878374
147262336	147262359	6	-	27260157	SF268	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	-0.338234959179212	[]	[]	-3	hSpCas9	negative selection	2878859
147260652	147260675	6	+	27260157	SF268	viability	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	-0.448047044445955	[]	[]	-4	hSpCas9	negative selection	2882258
147204557	147204580	6	+	27260157	SF268	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	0.802204305256522	[]	[]	8	hSpCas9	negative selection	2885526
147205989	147206012	6	-	27260157	SF268	viability	GCCAGGGCTGAGGGTTGATAGGG	STXBP5	ENSG00000164506	-0.110479945339477	[]	[]	-1	hSpCas9	negative selection	2886178
147278136	147278159	6	+	27260157	SF268	viability	CAGATGGCACCTTGACTATATGG	STXBP5	ENSG00000164506	0.310262603023263	[]	[]	4	hSpCas9	negative selection	2886691
147204616	147204639	6	+	27260157	SF268	viability	TCCGCCTGGGAACCGGGAGCCGG	STXBP5	ENSG00000164506	-1.35303718618599	[]	[]	-7	hSpCas9	negative selection	2889693
147315649	147315672	6	+	27260157	SF268	viability	AGTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	-0.448731318967424	[]	[]	-4	hSpCas9	negative selection	2890065
147313963	147313986	6	-	27260157	SF268	viability	AGTGCAGGAATAAGGTCCACAGG	STXBP5	ENSG00000164506	1.08926566054634	[]	[]	9	hSpCas9	negative selection	2892028
147206019	147206042	6	-	27260157	SF268	viability	ACTGCCAGGATCTTCTGTACAGG	STXBP5	ENSG00000164506	0.732823403474594	[]	[]	8	hSpCas9	negative selection	2914261
147205988	147206011	6	+	27260157	SF268	viability	TCCCTATCAACCCTCAGCCCTGG	STXBP5	ENSG00000164506	0.334097509825331	[]	[]	4	hSpCas9	negative selection	2914523
147204643	147204666	6	-	27260157	SF268	viability	GCTCGGACTGGAGCGTTTCCTGG	STXBP5	ENSG00000164506	0.477580237760913	[]	[]	7	hSpCas9	negative selection	2914664
147260639	147260662	6	-	27260157	SF268	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.182691996823132	[]	[]	0	hSpCas9	negative selection	2917852
147324969	147324992	6	+	27260157	SF268	viability	TCACCACTTAAACAGTCTCCAGG	STXBP5	ENSG00000164506	0.172429196279405	[]	[]	0	hSpCas9	negative selection	2920309
147262305	147262328	6	-	27260157	SF268	viability	TTATATGGACCACAGGTCCTGGG	STXBP5	ENSG00000164506	-0.0615971118759979	[]	[]	0	hSpCas9	negative selection	2921468
147235280	147235303	6	-	27260157	SF268	viability	CTGCAGCTCCACTGTCATGCTGG	STXBP5	ENSG00000164506	0.516632934657873	[]	[]	8	hSpCas9	negative selection	2947716
147315617	147315640	6	+	27260157	SF268	viability	ATGCCATTCAGATCATCTCCTGG	STXBP5	ENSG00000164506	-0.0702291022148559	[]	[]	0	hSpCas9	negative selection	2949258
147314261	147314284	6	+	27260157	SF268	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	-0.158577419068354	[]	[]	-1	hSpCas9	negative selection	2949550
147260639	147260662	6	+	27260157	SF268	viability	CCAGAGTAAGTGGCTCTATGTGG	STXBP5	ENSG00000164506	0.422647968390821	[]	[]	4	hSpCas9	negative selection	2949612
147316301	147316324	6	-	27260157	SF268	viability	TTGGACCCTCCCACGGGTGTTGG	STXBP5	ENSG00000164506	0.627526103942527	[]	[]	8	hSpCas9	negative selection	2951204
147316260	147316283	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGATGTGGAAACTCCGGAGGG	STXBP5	ENSG00000164506	0.3246794642429642	[3,3]	[3,4]	7	hSpCas9	positive selection	3024539
147278086	147278109	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	-0.3916325985888883	[2,2]	[3,0]	-5	hSpCas9	positive selection	3024540
147313978	147314001	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCAACAGAATAAAGTGCAGG	STXBP5	ENSG00000164506	-0.07427404951769243	[2,3]	[3,1]	-1	hSpCas9	positive selection	3024541
147278184	147278207	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACAGACAATCACTCCACATGG	STXBP5	ENSG00000164506	0.08520545126675252	[4,4]	[3,3]	1	hSpCas9	positive selection	3024542
147316260	147316283	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGATGTGGAAACTCCGGAGGG	STXBP5	ENSG00000164506	-0.2735743122033203	[3,3]	[3,0]	-4	hSpCas9	positive selection	3092397
147278086	147278109	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	-0.018855502669822333	[2,2]	[2,0]	0	hSpCas9	positive selection	3092398
147313978	147314001	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCAACAGAATAAAGTGCAGG	STXBP5	ENSG00000164506	-0.21640580136498855	[2,2]	[1,1]	-3	hSpCas9	positive selection	3092399
147278184	147278207	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACAGACAATCACTCCACATGG	STXBP5	ENSG00000164506	0.4512976533388574	[4,4]	[3,4]	7	hSpCas9	positive selection	3092400
147260639	147260662		-	24336571	A375	resistance to PLX after 7 days	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	-0.09216040060031494	[37,39]	[35,35]	-3	hSpCas9	positive selection	3148220
147239249	147239272		+	24336571	A375	resistance to PLX after 7 days	CGCTTAAATTTTGCAGAGAAAGG	STXBP5	ENSG00000164506	-0.261089863103923	[5,6]	[4,5]	-7	hSpCas9	positive selection	3148221
147260652	147260675		+	24336571	A375	resistance to PLX after 7 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	-0.27194663961740556	[10,15]	[10,10]	-7	hSpCas9	positive selection	3148222
147239169	147239192		+	24336571	A375	resistance to PLX after 7 days	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.16113686650350523	[6,6]	[6,7]	5	hSpCas9	positive selection	3148223
147260639	147260662		-	24336571	A375	resistance to PLX after 14 days	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.5847663092715454	[33,37]	[27,21]	5	hSpCas9	positive selection	3206013
147239249	147239272		+	24336571	A375	resistance to PLX after 14 days	CGCTTAAATTTTGCAGAGAAAGG	STXBP5	ENSG00000164506	-0.43816242743542366	[7,8]	[1,2]	-5	hSpCas9	positive selection	3206014
147260652	147260675		+	24336571	A375	resistance to PLX after 14 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	-0.861823305736257	[10,17]	[2,2]	-8	hSpCas9	positive selection	3206015
147239169	147239192		+	24336571	A375	resistance to PLX after 14 days	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.07286483247168929	[7,8]	[2,3]	0	hSpCas9	positive selection	3206016
147260639	147260662		-	24336571	A375	viability after 7 days	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.1049480988524385	[37]	[37,39]	1	hSpCas9	negative selection	3263806
147239249	147239272		+	24336571	A375	viability after 7 days	CGCTTAAATTTTGCAGAGAAAGG	STXBP5	ENSG00000164506	-0.5938593977793183	[10]	[5,6]	-7	hSpCas9	negative selection	3263807
147260652	147260675		+	24336571	A375	viability after 7 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.30929081786412715	[10]	[10,15]	5	hSpCas9	negative selection	3263808
147239169	147239192		+	24336571	A375	viability after 7 days	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.3841910212095259	[9]	[6,6]	-5	hSpCas9	negative selection	3263809
147260639	147260662		-	24336571	A375	viability after 14 days	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.022475508748315498	[37]	[33,37]	0	hSpCas9	negative selection	3321599
147239249	147239272		+	24336571	A375	viability after 14 days	CGCTTAAATTTTGCAGAGAAAGG	STXBP5	ENSG00000164506	-0.35194924215769563	[10]	[7,8]	-4	hSpCas9	negative selection	3321600
147260652	147260675		+	24336571	A375	viability after 14 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.41228069164722	[10]	[10,17]	5	hSpCas9	negative selection	3321601
147239169	147239192		+	24336571	A375	viability after 14 days	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.046012257115636	[9]	[7,8]	0	hSpCas9	negative selection	3321602
147239237	147239260	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	1.5024387092823666	[53,53]	[0,0]	6	hSpCas9	positive selection	3395569
147239169	147239192	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.9353981165584727	[79,79]	[0,0]	4	hSpCas9	positive selection	3395570
147262312	147262335	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-1.4569193062202874	[839,839]	[1,1]	-8	hSpCas9	positive selection	3395571
147316259	147316282	6	+	26780180	HT29	viability (Avana library 4 designs)	AATGATGTGGAAACTCCGGAGGG	STXBP5	ENSG00000164506	0.200645677949735	[]	[]	0	hSpCas9	negative selection	3463232
147278086	147278109	6	-	26780180	HT29	viability (Avana library 4 designs)	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	2.0218849377999	[]	[]	7	hSpCas9	negative selection	3463233
147313978	147314001	6	-	26780180	HT29	viability (Avana library 4 designs)	GCTCCAACAGAATAAAGTGCAGG	STXBP5	ENSG00000164506	2.67257784599583	[]	[]	8	hSpCas9	negative selection	3463234
147278183	147278206	6	+	26780180	HT29	viability (Avana library 4 designs)	GTACAGACAATCACTCCACATGG	STXBP5	ENSG00000164506	0.0744911393282851	[]	[]	0	hSpCas9	negative selection	3463235
147316259	147316282	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATGATGTGGAAACTCCGGAGGG	STXBP5	ENSG00000164506	-0.215830901072834	[]	[]	0	hSpCas9	negative selection	3565178
147278183	147278206	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTACAGACAATCACTCCACATGG	STXBP5	ENSG00000164506	-0.288400320982142	[]	[]	0	hSpCas9	negative selection	3565179
147313978	147314001	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCAACAGAATAAAGTGCAGG	STXBP5	ENSG00000164506	-0.772651125987444	[]	[]	-1	hSpCas9	negative selection	3565180
147278086	147278109	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	-6.39759419560178	[]	[]	-6	hSpCas9	negative selection	3565181
147204585	147204608	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGTTGCTGCTGCGACGCCGAGG	STXBP5	ENSG00000164506	5.15749155400851	[]	[]	8	hSpCas9	negative selection	3565182
147204617	147204640	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCCGGCTCCCGGTTCCCAGGCGG	STXBP5	ENSG00000164506	5.52433242397476	[]	[]	8	hSpCas9	negative selection	3565183
147316259	147316282	6	+	26780180	A375	viability (Avana lentiGuide)	AATGATGTGGAAACTCCGGAGGG	STXBP5	ENSG00000164506	-0.38426173736057	[]	[]	0	hSpCas9	negative selection	3673837
147278183	147278206	6	+	26780180	A375	viability (Avana lentiGuide)	GTACAGACAATCACTCCACATGG	STXBP5	ENSG00000164506	-4.78818299930747	[]	[]	-7	hSpCas9	negative selection	3673838
147313978	147314001	6	-	26780180	A375	viability (Avana lentiGuide)	GCTCCAACAGAATAAAGTGCAGG	STXBP5	ENSG00000164506	2.80342014486123	[]	[]	3	hSpCas9	negative selection	3673839
147278086	147278109	6	-	26780180	A375	viability (Avana lentiGuide)	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	-3.34317841693332	[]	[]	-6	hSpCas9	negative selection	3673840
147204585	147204608	6	-	26780180	A375	viability (Avana lentiGuide)	CTGTTGCTGCTGCGACGCCGAGG	STXBP5	ENSG00000164506	0.839144729975059	[]	[]	1	hSpCas9	negative selection	3673841
147204617	147204640	6	-	26780180	A375	viability (Avana lentiGuide)	TCCGGCTCCCGGTTCCCAGGCGG	STXBP5	ENSG00000164506	5.68447251638355	[]	[]	5	hSpCas9	negative selection	3673842
147316259	147316282	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGATGTGGAAACTCCGGAGGG	STXBP5	ENSG00000164506	0.04989387604510509	[5]	[6,5]	1	hSpCas9	positive selection	3782444
147278183	147278206	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACAGACAATCACTCCACATGG	STXBP5	ENSG00000164506	-0.430632041362249	[5]	[4,2]	-6	hSpCas9	positive selection	3782445
147313978	147314001	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCAACAGAATAAAGTGCAGG	STXBP5	ENSG00000164506	-0.1663050000927636	[3]	[3,3]	-3	hSpCas9	positive selection	3782446
147278086	147278109	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	-0.23934213009270466	[4]	[3,3]	-4	hSpCas9	positive selection	3782447
147204585	147204608	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGTTGCTGCTGCGACGCCGAGG	STXBP5	ENSG00000164506	0.25295379169773274	[4]	[5,5]	7	hSpCas9	positive selection	3782448
147204617	147204640	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCGGCTCCCGGTTCCCAGGCGG	STXBP5	ENSG00000164506	0.20663648569845847	[4]	[5,4]	6	hSpCas9	positive selection	3782449
147316259	147316282	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGATGTGGAAACTCCGGAGGG	STXBP5	ENSG00000164506	0.014745859349971517	[5]	[3,5]	0	hSpCas9	positive selection	3891051
147278183	147278206	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACAGACAATCACTCCACATGG	STXBP5	ENSG00000164506	-0.016647502063125375	[5]	[4,4]	0	hSpCas9	positive selection	3891052
147313978	147314001	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCAACAGAATAAAGTGCAGG	STXBP5	ENSG00000164506	-0.05048623891401427	[4]	[4,2]	0	hSpCas9	positive selection	3891053
147278086	147278109	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.39230583515174006	[4]	[5,4]	9	hSpCas9	positive selection	3891054
147204585	147204608	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGTTGCTGCTGCGACGCCGAGG	STXBP5	ENSG00000164506	-0.03409925323838216	[5]	[3,4]	0	hSpCas9	positive selection	3891055
147204617	147204640	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCGGCTCCCGGTTCCCAGGCGG	STXBP5	ENSG00000164506	-0.3850917514709137	[5]	[4,2]	-5	hSpCas9	positive selection	3891056
147239237	147239260	6	-	26780180	A375	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.845096322112106	[]	[]	3	hSpCas9	negative selection	4000717
147260639	147260662	6	-	26780180	A375	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	1.18265958215924	[]	[]	6	hSpCas9	negative selection	4000718
147239169	147239192	6	+	26780180	A375	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	1.37409262028944	[]	[]	7	hSpCas9	negative selection	4000719
147262336	147262359	6	-	26780180	A375	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	-0.171001323505375	[]	[]	-5	hSpCas9	negative selection	4000720
147260710	147260733	6	+	26780180	A375	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	-0.000440797453164443	[]	[]	0	hSpCas9	negative selection	4000721
147262312	147262335	6	-	26780180	A375	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	0.712148987753493	[]	[]	2	hSpCas9	negative selection	4000722
147239237	147239260	6	-	26780180	HT29	viability (GeCKOv2 library)	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.865364957335962	[]	[]	3	hSpCas9	negative selection	4108683
147260639	147260662	6	-	26780180	HT29	viability (GeCKOv2 library)	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	1.22456622301944	[]	[]	6	hSpCas9	negative selection	4108684
147239169	147239192	6	+	26780180	HT29	viability (GeCKOv2 library)	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	1.5707813120843	[]	[]	8	hSpCas9	negative selection	4108685
147262336	147262359	6	-	26780180	HT29	viability (GeCKOv2 library)	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.330342213022294	[]	[]	0	hSpCas9	negative selection	4108686
147260710	147260733	6	+	26780180	HT29	viability (GeCKOv2 library)	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.070031233127368	[]	[]	0	hSpCas9	negative selection	4108687
147262312	147262335	6	-	26780180	HT29	viability (GeCKOv2 library)	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	0.672305696930633	[]	[]	2	hSpCas9	negative selection	4108688
147260639	147260662	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.24378612719761172	[4]	[3,4]	6	hSpCas9	positive selection	4174467
147239249	147239272	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCTTAAATTTTGCAGAGAAAGG	STXBP5	ENSG00000164506	0.04961870298962989	[2]	[2,0]	1	hSpCas9	positive selection	4174468
147260652	147260675	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	-0.1258631053164262	[3]	[2,1]	-3	hSpCas9	positive selection	4174469
147239169	147239192	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.21498410206020035	[2]	[1,1]	-5	hSpCas9	positive selection	4174470
147260639	147260662	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.5751455145621247	[3]	[3,5,3,0]	4	hSpCas9	positive selection	4238489
147239249	147239272	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCTTAAATTTTGCAGAGAAAGG	STXBP5	ENSG00000164506	1.2980248870839306	[2]	[1,1,4,3]	9	hSpCas9	positive selection	4238490
147260652	147260675	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	-0.33850146103342266	[3]	[3,0,0,0]	-5	hSpCas9	positive selection	4238491
147239169	147239192	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	1.0982864583910856	[3]	[1,3,0,5]	8	hSpCas9	positive selection	4238492
147262336	147262359	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.50568040615211	[3]	[4,4]	9	hSpCas9	positive selection	4301299
147260710	147260733	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.1985457874626249	[4]	[5,2]	4	hSpCas9	positive selection	4301300
147260639	147260662	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.18155493202612025	[3]	[3,2]	3	hSpCas9	positive selection	4301301
147239237	147239260	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.5179135761051028	[1]	[1,0]	-8	hSpCas9	positive selection	4365554
147239169	147239192	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.06447399048317431	[2]	[1,1]	-1	hSpCas9	positive selection	4365555
147262312	147262335	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	0.3671539947282799	[5]	[5,6]	7	hSpCas9	positive selection	4365556
147314011	147314033	6	+	27760321	OCIAML3	viability	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	-0.7575723111772261	[173,117]	[67,64]	-6	hSpCas9	negative selection	4444231
147314262	147314284	6	+	27760321	OCIAML3	viability	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.27013992184281616	[627,520]	[423,689]	3	hSpCas9	negative selection	4444232
147315650	147315672	6	+	27760321	OCIAML3	viability	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	-0.025586564122380917	[828,714]	[528,672]	0	hSpCas9	negative selection	4444233
147235243	147235265	6	+	27760321	OCIAML3	viability	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	0.6732481868938989	[985,908]	[1053,1347]	7	hSpCas9	negative selection	4444234
147262328	147262350	6	+	27760321	OCIAML3	viability	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	0.7852735696513584	[194,169]	[201,301]	8	hSpCas9	negative selection	4444235
147314011	147314033	6	+	27760321	OCIAML2	viability	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	0.5250084608293888	[173,117]	[191,135]	7	hSpCas9	negative selection	4527694
147314262	147314284	6	+	27760321	OCIAML2	viability	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.6292262702601534	[627,520]	[653,796]	8	hSpCas9	negative selection	4527695
147315650	147315672	6	+	27760321	OCIAML2	viability	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	0.23360786140728385	[828,714]	[632,862]	3	hSpCas9	negative selection	4527696
147235243	147235265	6	+	27760321	OCIAML2	viability	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	-0.03671224996998146	[985,908]	[801,674]	0	hSpCas9	negative selection	4527697
147262328	147262350	6	+	27760321	OCIAML2	viability	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	0.31657736924174895	[194,169]	[182,183]	4	hSpCas9	negative selection	4527698
147314011	147314033	6	+	27760321	MV411	viability	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	0.22280941905823548	[173,117]	[152,47]	1	hSpCas9	negative selection	4611157
147314262	147314284	6	+	27760321	MV411	viability	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.3964259177150881	[627,520]	[290,805]	3	hSpCas9	negative selection	4611158
147315650	147315672	6	+	27760321	MV411	viability	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	0.33589887567162213	[828,714]	[659,612]	2	hSpCas9	negative selection	4611159
147235243	147235265	6	+	27760321	MV411	viability	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	0.685067027949823	[985,908]	[1029,967]	5	hSpCas9	negative selection	4611160
147262328	147262350	6	+	27760321	MV411	viability	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	0.7413191745002868	[194,169]	[26,461]	5	hSpCas9	negative selection	4611161
147314011	147314033	6	+	27760321	HL60	viability	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	0.9619608007539885	[173,117]	[110,354]	8	hSpCas9	negative selection	4694620
147314262	147314284	6	+	27760321	HL60	viability	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.8725137031046706	[627,520]	[787,926]	8	hSpCas9	negative selection	4694621
147315650	147315672	6	+	27760321	HL60	viability	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	-0.20865270290297722	[828,714]	[500,589]	-2	hSpCas9	negative selection	4694622
147235243	147235265	6	+	27760321	HL60	viability	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	0.15036562134423104	[985,908]	[973,736]	1	hSpCas9	negative selection	4694623
147262328	147262350	6	+	27760321	HL60	viability	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	1.0917342108810464	[194,169]	[382,246]	9	hSpCas9	negative selection	4694624
147314011	147314033	6	+	27760321	HT1080	viability	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	2.2924322147619423	[117,91]	[265,137]	9	hSpCas9	negative selection	4778083
147314262	147314284	6	+	27760321	HT1080	viability	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	1.6841821068165763	[520,406]	[731,442]	8	hSpCas9	negative selection	4778084
147315650	147315672	6	+	27760321	HT1080	viability	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	-1.3225187532583678	[714,557]	[119,80]	-5	hSpCas9	negative selection	4778085
147235243	147235265	6	+	27760321	HT1080	viability	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	-3.568604074450572	[908,709]	[30,22]	-7	hSpCas9	negative selection	4778086
147262328	147262350	6	+	27760321	HT1080	viability	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	3.1293067239472925	[169,132]	[552,500]	9	hSpCas9	negative selection	4778087
147314011	147314033	6	+	27760321	HT29	viability after 7 days	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	0.1315642951594742	[117,91]	[208,58,182]	2	hSpCas9	negative selection	4861546
147314262	147314284	6	+	27760321	HT29	viability after 7 days	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.4630053231769354	[520,406]	[1082,531,885]	7	hSpCas9	negative selection	4861547
147315650	147315672	6	+	27760321	HT29	viability after 7 days	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	-0.1790534933681448	[714,557]	[617,699,830]	-3	hSpCas9	negative selection	4861548
147235243	147235265	6	+	27760321	HT29	viability after 7 days	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	-0.16504639885165417	[908,709]	[1021,783,988]	-2	hSpCas9	negative selection	4861549
147262328	147262350	6	+	27760321	HT29	viability after 7 days	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	0.3597714630807963	[169,132]	[265,143,338]	5	hSpCas9	negative selection	4861550
147314011	147314033	6	+	27760321	HT29	viability after 25 days	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	1.3607234985714625	[117,91]	[293,424,193]	9	hSpCas9	negative selection	4945009
147314262	147314284	6	+	27760321	HT29	viability after 25 days	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	1.055994117737686	[520,406]	[1347,758,1192]	9	hSpCas9	negative selection	4945010
147315650	147315672	6	+	27760321	HT29	viability after 25 days	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	-0.16050828281667107	[714,557]	[517,711,738]	-2	hSpCas9	negative selection	4945011
147235243	147235265	6	+	27760321	HT29	viability after 25 days	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	0.4312534199633966	[908,709]	[1210,1179,1363]	5	hSpCas9	negative selection	4945012
147262328	147262350	6	+	27760321	HT29	viability after 25 days	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	0.7252114072321103	[169,132]	[200,399,259]	8	hSpCas9	negative selection	4945013
147314011	147314033	6	+	27760321	HT29	viability after 22 days	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	1.36190886600944	[117,91]	[289,385,259]	9	hSpCas9	negative selection	5028472
147314262	147314284	6	+	27760321	HT29	viability after 22 days	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.9139361201174889	[520,406]	[872,1038,1124]	9	hSpCas9	negative selection	5028473
147315650	147315672	6	+	27760321	HT29	viability after 22 days	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	0.29424251536757595	[714,557]	[760,1221,725]	3	hSpCas9	negative selection	5028474
147235243	147235265	6	+	27760321	HT29	viability after 22 days	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	0.32604077563735334	[908,709]	[1058,1348,1113]	3	hSpCas9	negative selection	5028475
147262328	147262350	6	+	27760321	HT29	viability after 22 days	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	0.35729146784210897	[169,132]	[178,207,287]	4	hSpCas9	negative selection	5028476
147314011	147314033	6	+	27760321	HT29	viability after 19 days	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	0.7314145850739155	[117,91]	[193,273,131]	7	hSpCas9	negative selection	5111935
147314262	147314284	6	+	27760321	HT29	viability after 19 days	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.741762293288942	[520,406]	[913,956,796]	7	hSpCas9	negative selection	5111936
147315650	147315672	6	+	27760321	HT29	viability after 19 days	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	0.05840636152931511	[714,557]	[489,1278,486]	0	hSpCas9	negative selection	5111937
147235243	147235265	6	+	27760321	HT29	viability after 19 days	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	0.6101366025030304	[908,709]	[1400,982,1836]	6	hSpCas9	negative selection	5111938
147262328	147262350	6	+	27760321	HT29	viability after 19 days	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	-0.30756141291545536	[169,132]	[159,39,218]	-3	hSpCas9	negative selection	5111939
147314011	147314033	6	+	27760321	HT29	viability after 16 days	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	1.4343655270266367	[117,91]	[253,407,281]	9	hSpCas9	negative selection	5195398
147314262	147314284	6	+	27760321	HT29	viability after 16 days	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.6191828775087718	[520,406]	[926,773,703]	7	hSpCas9	negative selection	5195399
147315650	147315672	6	+	27760321	HT29	viability after 16 days	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	0.42348543504529557	[714,557]	[682,1082,1069]	5	hSpCas9	negative selection	5195400
147235243	147235265	6	+	27760321	HT29	viability after 16 days	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	0.5545372276066085	[908,709]	[1404,1196,1398]	6	hSpCas9	negative selection	5195401
147262328	147262350	6	+	27760321	HT29	viability after 16 days	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	0.5361318197243525	[169,132]	[251,322,160]	6	hSpCas9	negative selection	5195402
147314011	147314033	6	+	27760321	HT29	viability after 13 days	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	1.5976579887040687	[117,91]	[471,407,233]	9	hSpCas9	negative selection	5278861
147314262	147314284	6	+	27760321	HT29	viability after 13 days	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.8552438862787051	[520,406]	[824,939,1145]	9	hSpCas9	negative selection	5278862
147315650	147315672	6	+	27760321	HT29	viability after 13 days	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	0.29654306569145394	[714,557]	[504,1232,978]	4	hSpCas9	negative selection	5278863
147235243	147235265	6	+	27760321	HT29	viability after 13 days	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	0.11045333102493538	[908,709]	[1319,864,864]	1	hSpCas9	negative selection	5278864
147262328	147262350	6	+	27760321	HT29	viability after 13 days	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	-0.548530573990536	[169,132]	[111,135,112]	-6	hSpCas9	negative selection	5278865
147314011	147314033	6	+	27760321	HT29	viability after 10 days	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	0.6575456516809339	[117,91]	[263,174,180]	8	hSpCas9	negative selection	5362324
147314262	147314284	6	+	27760321	HT29	viability after 10 days	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.4887653742338302	[520,406]	[1002,991,456]	6	hSpCas9	negative selection	5362325
147315650	147315672	6	+	27760321	HT29	viability after 10 days	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	-0.07973075320500422	[714,557]	[611,998,653]	-1	hSpCas9	negative selection	5362326
147235243	147235265	6	+	27760321	HT29	viability after 10 days	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	0.25026689144182734	[908,709]	[1670,842,1084]	3	hSpCas9	negative selection	5362327
147262328	147262350	6	+	27760321	HT29	viability after 10 days	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	-0.6788097822510017	[169,132]	[63,131,157]	-7	hSpCas9	negative selection	5362328
147314011	147314033	6	+	27760321	MOLM13	viability	CGTCAAGGTTACAGCAAAAAGG	STXBP5	ENSG00000164506	0.9470677360805474	[173,117]	[185,131]	6	hSpCas9	negative selection	5445787
147314262	147314284	6	+	27760321	MOLM13	viability	AGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	1.0836740645266052	[627,520]	[838,551]	7	hSpCas9	negative selection	5445788
147315650	147315672	6	+	27760321	MOLM13	viability	GTAGAATGCTGTGCATCGCTGG	STXBP5	ENSG00000164506	-0.3553569084051351	[828,714]	[271,396]	-2	hSpCas9	negative selection	5445789
147235243	147235265	6	+	27760321	MOLM13	viability	ATTACAGCTTTGGTCGTCCAGG	STXBP5	ENSG00000164506	0.532983821405786	[985,908]	[1022,560]	3	hSpCas9	negative selection	5445790
147262328	147262350	6	+	27760321	MOLM13	viability	GTGATAATCCAATGGACGAGGG	STXBP5	ENSG00000164506	-1.3343737741501118	[194,169]	[50,31]	-6	hSpCas9	negative selection	5445791
147204422	147204445	6	-	27661255	K562	viability	GACCGCGGAAACGGAGGAGTGGG	STXBP5	ENSG00000164506	0.11679955361148586	[451,434]	[405,365]	4	dCas9-KRAB	negative selection	5515085
147262336	147262359	6	-	27260156	BXPC3	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.2631390618916273	[916]	[1064,866,1394,1318]	6	hSpCas9	negative selection	5573759
147260710	147260733	6	+	27260156	BXPC3	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.14292674683136464	[1289]	[1310,1320,1652,1722]	3	hSpCas9	negative selection	5573760
147260639	147260662	6	-	27260156	BXPC3	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.045325715568670155	[813]	[842,707,1051,926]	1	hSpCas9	negative selection	5573761
147239237	147239260	6	-	27260156	BXPC3	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.10606507729871018	[177]	[192,179,167,142]	-2	hSpCas9	negative selection	5638014
147239169	147239192	6	+	27260156	BXPC3	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.032964854903252516	[232]	[271,225,238,257]	0	hSpCas9	negative selection	5638015
147262312	147262335	6	-	27260156	BXPC3	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.3643145928911826	[3219]	[2615,2398,2652,2812]	-7	hSpCas9	negative selection	5638016
147262336	147262359	6	-	27260156	A673	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.48919942893954993	[916]	[1717,1378,1489,1620]	9	hSpCas9	negative selection	5695010
147260710	147260733	6	+	27260156	A673	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.34179274059849396	[1289]	[2211,1810,1843,2017]	7	hSpCas9	negative selection	5695011
147260639	147260662	6	-	27260156	A673	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.002526637860773562	[813]	[1020,961,883,1057]	0	hSpCas9	negative selection	5695012
147239237	147239260	6	-	27260156	A673	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.332903793484276	[177]	[213,172,109,187]	-7	hSpCas9	negative selection	5759265
147239169	147239192	6	+	27260156	A673	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.0625802138978152	[232]	[338,330,228,272]	1	hSpCas9	negative selection	5759266
147262312	147262335	6	-	27260156	A673	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.46216042751715314	[3219]	[2989,2721,2693,2840]	-8	hSpCas9	negative selection	5759267
147262336	147262359	6	-	27260156	A375	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.1996160343801593	[916]	[1366,1467,946,1173]	3	hSpCas9	negative selection	5816261
147260710	147260733	6	+	27260156	A375	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.3868948776017662	[1289]	[2274,2316,2189,1230]	5	hSpCas9	negative selection	5816262
147260639	147260662	6	-	27260156	A375	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.20097124260918464	[813]	[1121,1287,1034,964]	3	hSpCas9	negative selection	5816263
147239237	147239260	6	-	27260156	A375	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.12821211090347595	[177]	[178,190,262,133]	-2	hSpCas9	negative selection	5880516
147239169	147239192	6	+	27260156	A375	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.039910404689152745	[232]	[200,342,247,274]	0	hSpCas9	negative selection	5880517
147262312	147262335	6	-	27260156	A375	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.42247094068681745	[3219]	[2429,3478,2786,2629]	-5	hSpCas9	negative selection	5880518
147262336	147262359	6	-	27260156	COLO741	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.38183073211459917	[916]	[1740,1461,1400]	7	hSpCas9	negative selection	5937512
147260710	147260733	6	+	27260156	COLO741	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.14691436943343228	[1289]	[2133,1895,1491]	3	hSpCas9	negative selection	5937513
147260639	147260662	6	-	27260156	COLO741	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	-0.029210705129630532	[813]	[965,1205,888]	0	hSpCas9	negative selection	5937514
147239237	147239260	6	-	27260156	COLO741	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.016902617724818825	[177]	[233,237,218]	0	hSpCas9	negative selection	6001767
147239169	147239192	6	+	27260156	COLO741	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.3667982893812616	[232]	[237,269,187]	-7	hSpCas9	negative selection	6001768
147262312	147262335	6	-	27260156	COLO741	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.5054436622086897	[3219]	[3250,2785,2695]	-8	hSpCas9	negative selection	6001769
147262336	147262359	6	-	27260156	CAL120	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.6595111391866705	[916]	[2483,1441,1586]	8	hSpCas9	negative selection	6058763
147260710	147260733	6	+	27260156	CAL120	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.2663812152830709	[1289]	[2113,1599,2101]	4	hSpCas9	negative selection	6058764
147260639	147260662	6	-	27260156	CAL120	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.41077562496245	[813]	[1628,1513,945]	6	hSpCas9	negative selection	6058765
147239237	147239260	6	-	27260156	CAL120	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.9010894485632559	[177]	[137,118,101]	-8	hSpCas9	negative selection	6123018
147239169	147239192	6	+	27260156	CAL120	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.02568162425069964	[232]	[479,245,159]	0	hSpCas9	negative selection	6123019
147262312	147262335	6	-	27260156	CAL120	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.5688377497527313	[3219]	[2925,2642,2569]	-7	hSpCas9	negative selection	6123020
147262336	147262359	6	-	27260156	CADOES1	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.41863106996336474	[916]	[1065,1036,1211,1248]	7	hSpCas9	negative selection	6180014
147260710	147260733	6	+	27260156	CADOES1	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.40048127968699365	[1289]	[1332,1594,1674,1737]	6	hSpCas9	negative selection	6180015
147260639	147260662	6	-	27260156	CADOES1	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.12579987647261692	[813]	[739,914,812,836]	2	hSpCas9	negative selection	6180016
147239237	147239260	6	-	27260156	CADOES1	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.17025994372482556	[177]	[144,156,184,260]	3	hSpCas9	negative selection	6244269
147239169	147239192	6	+	27260156	CADOES1	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.19045410650369465	[232]	[185,228,172,170]	-3	hSpCas9	negative selection	6244270
147262312	147262335	6	-	27260156	CADOES1	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.5092614928873145	[3219]	[2032,1957,2044,2390]	-7	hSpCas9	negative selection	6244271
147262336	147262359	6	-	27260156	EWS502	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.5195318506890209	[916]	[1240,1215,1539,1609]	8	hSpCas9	negative selection	6301265
147260710	147260733	6	+	27260156	EWS502	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.415168562565275	[1289]	[1515,2134,2076,1561]	7	hSpCas9	negative selection	6301266
147260639	147260662	6	-	27260156	EWS502	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.07537810663206379	[813]	[850,955,924,902]	1	hSpCas9	negative selection	6301267
147239237	147239260	6	-	27260156	EWS502	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.2171855063361845	[177]	[123,56,141,346]	-4	hSpCas9	negative selection	6365520
147239169	147239192	6	+	27260156	EWS502	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.012066145947147167	[232]	[233,279,147,337]	0	hSpCas9	negative selection	6365521
147262312	147262335	6	-	27260156	EWS502	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.5899012112760742	[3219]	[1987,2072,2384,2681]	-7	hSpCas9	negative selection	6365522
147262336	147262359	6	-	27260156	EW8	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.41052310518578194	[916]	[1278,852,861,1006]	7	hSpCas9	negative selection	6422516
147260710	147260733	6	+	27260156	EW8	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.4013350498315278	[1289]	[1599,1536,1055,1405]	7	hSpCas9	negative selection	6422517
147260639	147260662	6	-	27260156	EW8	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.10573848700596333	[813]	[810,878,649,519]	2	hSpCas9	negative selection	6422518
147239237	147239260	6	-	27260156	EW8	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.012998727788420483	[177]	[168,96,154,150]	0	hSpCas9	negative selection	6486771
147239169	147239192	6	+	27260156	EW8	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.8937763538602175	[232]	[218,723,166,310]	9	hSpCas9	negative selection	6486772
147262312	147262335	6	-	27260156	EW8	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.3928297213887024	[3219]	[2422,2009,1636,1981]	-6	hSpCas9	negative selection	6486773
147262336	147262359	6	-	27260156	CORL105	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.394065001740903	[916]	[1206,1214,1913,1381]	7	hSpCas9	negative selection	6543767
147260710	147260733	6	+	27260156	CORL105	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.3440997104707011	[1289]	[1773,1904,2392,1665]	6	hSpCas9	negative selection	6543768
147260639	147260662	6	-	27260156	CORL105	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.13568126214867082	[813]	[1079,889,1240,1010]	2	hSpCas9	negative selection	6543769
147239237	147239260	6	-	27260156	CORL105	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.18266730112906382	[177]	[180,137,283,147]	-3	hSpCas9	negative selection	6608022
147239169	147239192	6	+	27260156	CORL105	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.05314302413290717	[232]	[270,265,257,255]	-1	hSpCas9	negative selection	6608023
147262312	147262335	6	-	27260156	CORL105	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.25298859472636304	[3219]	[3237,2713,3726,3072]	-5	hSpCas9	negative selection	6608024
147262336	147262359	6	-	27260156	HS294T	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.12738680006651937	[916]	[312,383,416,451]	1	hSpCas9	negative selection	6665018
147260710	147260733	6	+	27260156	HS294T	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.35200234035202094	[1289]	[410,680,659,847]	5	hSpCas9	negative selection	6665019
147260639	147260662	6	-	27260156	HS294T	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.13108354224182106	[813]	[286,306,352,455]	1	hSpCas9	negative selection	6665020
147239237	147239260	6	-	27260156	HS294T	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.06279170781560706	[177]	[76,85,72,45]	0	hSpCas9	negative selection	6729273
147239169	147239192	6	+	27260156	HS294T	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.4732030977601176	[232]	[59,89,43,64]	-6	hSpCas9	negative selection	6729274
147262312	147262335	6	-	27260156	HS294T	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.23423402507370206	[3219]	[859,1119,920,1403]	-3	hSpCas9	negative selection	6729275
147262336	147262359	6	-	27260156	HCC44	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.355823669027843	[916]	[1014,1190,1758,1395]	6	hSpCas9	negative selection	6786269
147260710	147260733	6	+	27260156	HCC44	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.3820568483238098	[1289]	[2044,1487,2727,1554]	6	hSpCas9	negative selection	6786270
147260639	147260662	6	-	27260156	HCC44	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.22421870791849263	[813]	[1195,795,948,1370]	3	hSpCas9	negative selection	6786271
147239237	147239260	6	-	27260156	HCC44	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.40019876610556127	[177]	[407,143,111,395]	6	hSpCas9	negative selection	6850524
147239169	147239192	6	+	27260156	HCC44	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.20708230377755166	[232]	[281,213,558,216]	3	hSpCas9	negative selection	6850525
147262312	147262335	6	-	27260156	HCC44	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.3264578926988775	[3219]	[2605,2537,3171,3333]	-5	hSpCas9	negative selection	6850526
147262336	147262359	6	-	27260156	G402	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.8750695596535628	[916]	[1697,2812,2415,1303]	9	hSpCas9	negative selection	6907520
147260710	147260733	6	+	27260156	G402	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.313916954682802	[1289]	[2295,2340,1689,1581]	4	hSpCas9	negative selection	6907521
147260639	147260662	6	-	27260156	G402	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.2840330729972894	[813]	[1387,1309,1244,934]	3	hSpCas9	negative selection	6907522
147239237	147239260	6	-	27260156	G402	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.022101097301804318	[177]	[299,207,211,149]	0	hSpCas9	negative selection	6971775
147239169	147239192	6	+	27260156	G402	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.5333969370897436	[232]	[204,449,88,850]	6	hSpCas9	negative selection	6971776
147262312	147262335	6	-	27260156	G402	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.27074001458311203	[3219]	[3223,2695,3713,3338]	-3	hSpCas9	negative selection	6971777
147262336	147262359	6	-	27260156	L33	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.40963366140803836	[916]	[1303,449,617,1480]	8	hSpCas9	negative selection	7028771
147260710	147260733	6	+	27260156	L33	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.37010873597834015	[1289]	[1638,743,1062,1524]	7	hSpCas9	negative selection	7028772
147260639	147260662	6	-	27260156	L33	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.24639673916323035	[813]	[1002,428,544,943]	5	hSpCas9	negative selection	7028773
147239237	147239260	6	-	27260156	L33	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.27225299146409476	[177]	[163,70,89,108]	-6	hSpCas9	negative selection	7093026
147239169	147239192	6	+	27260156	L33	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.6694031951869002	[232]	[138,70,94,122]	-9	hSpCas9	negative selection	7093027
147262312	147262335	6	-	27260156	L33	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.3844378199530385	[3219]	[2101,1123,1566,2536]	-7	hSpCas9	negative selection	7093028
147262336	147262359	6	-	27260156	K562	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.23511337665348753	[916]	[1046,827,988,962]	3	hSpCas9	negative selection	7150022
147260710	147260733	6	+	27260156	K562	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	-0.15558802073741074	[1289]	[1275,1045,901,916]	-2	hSpCas9	negative selection	7150023
147260639	147260662	6	-	27260156	K562	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.1323711451916243	[813]	[843,937,585,805]	1	hSpCas9	negative selection	7150024
147239237	147239260	6	-	27260156	K562	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.48438332218563906	[177]	[153,74,114,108]	-5	hSpCas9	negative selection	7214277
147239169	147239192	6	+	27260156	K562	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.28802503852338	[232]	[447,264,187,137]	3	hSpCas9	negative selection	7214278
147262312	147262335	6	-	27260156	K562	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.47576294364405713	[3219]	[2125,3341,1818,1108]	-5	hSpCas9	negative selection	7214279
147262336	147262359	6	-	27260156	HT29	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.4331750484187037	[916]	[1491,1506,1427,1572]	8	hSpCas9	negative selection	7271273
147260710	147260733	6	+	27260156	HT29	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.27881819393531293	[1289]	[2020,1968,1818,1812]	5	hSpCas9	negative selection	7271274
147260639	147260662	6	-	27260156	HT29	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.2848422176062665	[813]	[1333,1532,1207,823]	5	hSpCas9	negative selection	7271275
147239237	147239260	6	-	27260156	HT29	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.04608749387496669	[177]	[137,222,266,204]	-1	hSpCas9	negative selection	7335528
147239169	147239192	6	+	27260156	HT29	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.0718037359445709	[232]	[238,407,289,161]	-1	hSpCas9	negative selection	7335529
147262312	147262335	6	-	27260156	HT29	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.4846328968564917	[3219]	[3034,3095,2874,2272]	-7	hSpCas9	negative selection	7335530
147262336	147262359	6	-	27260156	MHHES1	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.5282931861493593	[916]	[1394,1970,1405,1245]	8	hSpCas9	negative selection	7392524
147260710	147260733	6	+	27260156	MHHES1	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.4339747991823557	[1289]	[2419,2308,1863,1428]	7	hSpCas9	negative selection	7392525
147260639	147260662	6	-	27260156	MHHES1	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.1842981240140631	[813]	[1347,1087,997,805]	3	hSpCas9	negative selection	7392526
147239237	147239260	6	-	27260156	MHHES1	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.5544543123664589	[177]	[298,245,328,292]	8	hSpCas9	negative selection	7456779
147239169	147239192	6	+	27260156	MHHES1	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.19658783767778965	[232]	[272,212,233,200]	-4	hSpCas9	negative selection	7456780
147262312	147262335	6	-	27260156	MHHES1	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.30964931540581153	[3219]	[3268,3476,2594,2492]	-5	hSpCas9	negative selection	7456781
147262336	147262359	6	-	27260156	MEWO	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.3435435404985888	[916]	[1042,1017,1195]	7	hSpCas9	negative selection	7513775
147260710	147260733	6	+	27260156	MEWO	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.3127563317319746	[1289]	[1948,1281,1353]	6	hSpCas9	negative selection	7513776
147260639	147260662	6	-	27260156	MEWO	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.09328016932341254	[813]	[1125,773,597]	2	hSpCas9	negative selection	7513777
147239237	147239260	6	-	27260156	MEWO	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.08627682041610085	[177]	[220,156,160]	2	hSpCas9	negative selection	7578030
147239169	147239192	6	+	27260156	MEWO	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.03443858944098577	[232]	[335,130,224]	0	hSpCas9	negative selection	7578031
147262312	147262335	6	-	27260156	MEWO	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.4570171912759968	[3219]	[2613,1891,2159]	-7	hSpCas9	negative selection	7578032
147262336	147262359	6	-	27260156	LNCAPCLONEFGC	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.139963225441058	[916]	[971,878,1104,733]	2	hSpCas9	negative selection	7635026
147260710	147260733	6	+	27260156	LNCAPCLONEFGC	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.26215995767248446	[1289]	[1378,1186,1897,1228]	4	hSpCas9	negative selection	7635027
147260639	147260662	6	-	27260156	LNCAPCLONEFGC	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.14565818557701682	[813]	[628,804,1141,738]	2	hSpCas9	negative selection	7635028
147239237	147239260	6	-	27260156	LNCAPCLONEFGC	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.3506132825571122	[177]	[168,59,83,189]	-5	hSpCas9	negative selection	7699281
147239169	147239192	6	+	27260156	LNCAPCLONEFGC	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.0042421626989612715	[232]	[187,200,219,239]	0	hSpCas9	negative selection	7699282
147262312	147262335	6	-	27260156	LNCAPCLONEFGC	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.5664152086077716	[3219]	[1963,1777,2128,2042]	-7	hSpCas9	negative selection	7699283
147262336	147262359	6	-	27260156	PANC0327	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.09261817565193897	[916]	[972,980,746,766]	1	hSpCas9	negative selection	7756277
147260710	147260733	6	+	27260156	PANC0327	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.2467355410501184	[1289]	[1305,1629,1328,1133]	3	hSpCas9	negative selection	7756278
147260639	147260662	6	-	27260156	PANC0327	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	-0.4557126603739496	[813]	[422,653,567,438]	-6	hSpCas9	negative selection	7756279
147239237	147239260	6	-	27260156	PANC0327	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.36646379955369146	[177]	[576,116,80,81]	5	hSpCas9	negative selection	7820532
147239169	147239192	6	+	27260156	PANC0327	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.4856750971141627	[232]	[89,218,391,450]	7	hSpCas9	negative selection	7820533
147262312	147262335	6	-	27260156	PANC0327	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.1930507706304394	[3219]	[2916,2266,2455,2431]	-3	hSpCas9	negative selection	7820534
147262336	147262359	6	-	27260156	NCIH2009	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.11963336265245383	[916]	[1572,1408,1226]	1	hSpCas9	negative selection	7877528
147260710	147260733	6	+	27260156	NCIH2009	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.33491642378803643	[1289]	[2467,1969,2421]	4	hSpCas9	negative selection	7877529
147260639	147260662	6	-	27260156	NCIH2009	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.1817742368575238	[813]	[1464,870,1573]	2	hSpCas9	negative selection	7877530
147239237	147239260	6	-	27260156	NCIH2009	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.1715915800207768	[177]	[299,148,229]	-2	hSpCas9	negative selection	7941783
147239169	147239192	6	+	27260156	NCIH2009	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.11063489576327501	[232]	[334,280,294]	-1	hSpCas9	negative selection	7941784
147262312	147262335	6	-	27260156	NCIH2009	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.30621204246215195	[3219]	[3771,3621,3541]	-4	hSpCas9	negative selection	7941785
147262336	147262359	6	-	27260156	NCIH1373	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.2022816012760874	[916]	[1576,897,1203,297]	2	hSpCas9	negative selection	7998779
147260710	147260733	6	+	27260156	NCIH1373	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.6895451297562047	[1289]	[2478,2014,2180,715]	7	hSpCas9	negative selection	7998780
147260639	147260662	6	-	27260156	NCIH1373	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	-0.027739305995196917	[813]	[675,846,934,288]	0	hSpCas9	negative selection	7998781
147239237	147239260	6	-	27260156	NCIH1373	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.3944767220086147	[177]	[533,137,268,40]	4	hSpCas9	negative selection	8063034
147239169	147239192	6	+	27260156	NCIH1373	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.17280257687067047	[232]	[578,245,247,37]	1	hSpCas9	negative selection	8063035
147262312	147262335	6	-	27260156	NCIH1373	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.010684815211051024	[3219]	[3339,2397,3791,1300]	0	hSpCas9	negative selection	8063036
147262336	147262359	6	-	27260156	PATU8902	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.44658204599224394	[916]	[1647,1674,1773,1856]	4	hSpCas9	negative selection	8120030
147260710	147260733	6	+	27260156	PATU8902	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.42353418006355237	[1289]	[2416,1992,2298,3008]	4	hSpCas9	negative selection	8120031
147260639	147260662	6	-	27260156	PATU8902	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.2359317719327262	[813]	[1016,1403,1218,1776]	2	hSpCas9	negative selection	8120032
147239237	147239260	6	-	27260156	PATU8902	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.40830666859841847	[177]	[306,467,286,253]	4	hSpCas9	negative selection	8184285
147239169	147239192	6	+	27260156	PATU8902	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.5674483083160693	[232]	[244,471,468,774]	6	hSpCas9	negative selection	8184286
147262312	147262335	6	-	27260156	PATU8902	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.35182492866019777	[3219]	[3868,3706,2441,4388]	-4	hSpCas9	negative selection	8184287
147262336	147262359	6	-	27260156	PANC1	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.5546105340614867	[916]	[953,1499,1202,1044]	8	hSpCas9	negative selection	8241281
147260710	147260733	6	+	27260156	PANC1	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.47165915404930714	[1289]	[1440,1765,1733,1273]	7	hSpCas9	negative selection	8241282
147260639	147260662	6	-	27260156	PANC1	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	9.237847067256055e-05	[813]	[691,930,639,587]	0	hSpCas9	negative selection	8241283
147239237	147239260	6	-	27260156	PANC1	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.1310506276962935	[177]	[215,219,185,70]	2	hSpCas9	negative selection	8305536
147239169	147239192	6	+	27260156	PANC1	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.2535817979415107	[232]	[178,324,323,155]	4	hSpCas9	negative selection	8305537
147262312	147262335	6	-	27260156	PANC1	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.25210933377411715	[3219]	[2094,3004,2589,1795]	-4	hSpCas9	negative selection	8305538
147262336	147262359	6	-	27260156	PANC0813	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.13949963947372013	[916]	[1398,1241,1287,853]	2	hSpCas9	negative selection	8362532
147260710	147260733	6	+	27260156	PANC0813	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.2947153670020197	[1289]	[2098,1895,1809,1659]	5	hSpCas9	negative selection	8362533
147260639	147260662	6	-	27260156	PANC0813	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.25222699024214645	[813]	[1226,920,1114,1289]	4	hSpCas9	negative selection	8362534
147239237	147239260	6	-	27260156	PANC0813	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.214245300043032	[177]	[170,118,315,117]	-3	hSpCas9	negative selection	8426787
147239169	147239192	6	+	27260156	PANC0813	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.4078764826355936	[232]	[197,301,141,182]	-6	hSpCas9	negative selection	8426788
147262312	147262335	6	-	27260156	PANC0813	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.4856520535115787	[3219]	[3676,2382,2398,2444]	-6	hSpCas9	negative selection	8426789
147262336	147262359	6	-	27260156	RDES	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.4897825254147373	[916]	[1353,1261,1387,1995]	7	hSpCas9	negative selection	8483783
147260710	147260733	6	+	27260156	RDES	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.14771828220454863	[1289]	[1535,1475,1536,2071]	2	hSpCas9	negative selection	8483784
147260639	147260662	6	-	27260156	RDES	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	-0.014054144423897741	[813]	[722,961,1070,977]	0	hSpCas9	negative selection	8483785
147239237	147239260	6	-	27260156	RDES	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.21620647555622563	[177]	[156,230,152,151]	-4	hSpCas9	negative selection	8548038
147239169	147239192	6	+	27260156	RDES	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.09101187921326237	[232]	[166,327,308,199]	-1	hSpCas9	negative selection	8548039
147262312	147262335	6	-	27260156	RDES	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.5628781968561025	[3219]	[2119,2226,2531,3304]	-7	hSpCas9	negative selection	8548040
147262336	147262359	6	-	27260156	PC3	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.32300602594280436	[916]	[720,1123,1935,1176]	7	hSpCas9	negative selection	8605034
147260710	147260733	6	+	27260156	PC3	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.3677807058423852	[1289]	[1084,1756,2440,1737]	7	hSpCas9	negative selection	8605035
147260639	147260662	6	-	27260156	PC3	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.0026506881403609572	[813]	[552,686,1504,812]	0	hSpCas9	negative selection	8605036
147239237	147239260	6	-	27260156	PC3	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	0.27066521253827314	[177]	[158,143,474,182]	6	hSpCas9	negative selection	8669289
147239169	147239192	6	+	27260156	PC3	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.056875303039485514	[232]	[145,236,287,258]	-1	hSpCas9	negative selection	8669290
147262312	147262335	6	-	27260156	PC3	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.49275085518560635	[3219]	[1384,2517,3493,2362]	-8	hSpCas9	negative selection	8669291
147262336	147262359	6	-	27260156	PATU8988T	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.4460862074310036	[916]	[1102,1356,861,1552]	7	hSpCas9	negative selection	8726285
147260710	147260733	6	+	27260156	PATU8988T	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.29225099131735943	[1289]	[1367,1631,1621,1488]	5	hSpCas9	negative selection	8726286
147260639	147260662	6	-	27260156	PATU8988T	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.26471005657220237	[813]	[991,951,785,1061]	4	hSpCas9	negative selection	8726287
147239237	147239260	6	-	27260156	PATU8988T	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.27447457577052004	[177]	[174,139,189,55]	-5	hSpCas9	negative selection	8790540
147239169	147239192	6	+	27260156	PATU8988T	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.028045575777601472	[232]	[203,215,343,107]	0	hSpCas9	negative selection	8790541
147262312	147262335	6	-	27260156	PATU8988T	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.4184802783131687	[3219]	[1837,2754,2275,2496]	-6	hSpCas9	negative selection	8790542
147262336	147262359	6	-	27260156	T47D	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.5549864139381201	[916]	[1612,1577,1550,1533]	9	hSpCas9	negative selection	8847536
147260710	147260733	6	+	27260156	T47D	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.3567233740116935	[1289]	[2075,1615,1954,2081]	7	hSpCas9	negative selection	8847537
147260639	147260662	6	-	27260156	T47D	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.23093801247384482	[813]	[1183,976,1152,1149]	5	hSpCas9	negative selection	8847538
147239237	147239260	6	-	27260156	T47D	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.14039151054021648	[177]	[171,198,159,221]	-3	hSpCas9	negative selection	8911791
147239169	147239192	6	+	27260156	T47D	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.15880277469705673	[232]	[280,365,259,299]	3	hSpCas9	negative selection	8911792
147262312	147262335	6	-	27260156	T47D	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.352255212950646	[3219]	[3128,2680,2968,2998]	-6	hSpCas9	negative selection	8911793
147262336	147262359	6	-	27260156	SU8686	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.38973511797464144	[916]	[901,1163,1345,1421]	6	hSpCas9	negative selection	8968787
147260710	147260733	6	+	27260156	SU8686	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.3065529235849258	[1289]	[1370,1324,2018,1686]	5	hSpCas9	negative selection	8968788
147260639	147260662	6	-	27260156	SU8686	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.25535645539413976	[813]	[693,838,1019,1414]	4	hSpCas9	negative selection	8968789
147239237	147239260	6	-	27260156	SU8686	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.0733886281388536	[177]	[125,171,171,210]	-1	hSpCas9	negative selection	9033042
147239169	147239192	6	+	27260156	SU8686	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.24811068987903218	[232]	[193,174,220,188]	-4	hSpCas9	negative selection	9033043
147262312	147262335	6	-	27260156	SU8686	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.3659637089569472	[3219]	[2146,2317,2540,3034]	-6	hSpCas9	negative selection	9033044
147262336	147262359	6	-	27260156	SKES1	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.2780252645002511	[916]	[1373,1091,1069,943]	6	hSpCas9	negative selection	9090038
147260710	147260733	6	+	27260156	SKES1	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.21873805843230643	[1289]	[1765,1355,1502,1382]	4	hSpCas9	negative selection	9090039
147260639	147260662	6	-	27260156	SKES1	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.04448385108144437	[813]	[818,921,892,726]	1	hSpCas9	negative selection	9090040
147239237	147239260	6	-	27260156	SKES1	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.23623019745192364	[177]	[147,218,185,65]	-5	hSpCas9	negative selection	9154293
147239169	147239192	6	+	27260156	SKES1	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.2890210491759313	[232]	[161,197,166,224]	-6	hSpCas9	negative selection	9154294
147262312	147262335	6	-	27260156	SKES1	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.4630258105093392	[3219]	[2595,2636,2158,2017]	-8	hSpCas9	negative selection	9154295
147262336	147262359	6	-	27260156	TOV112D	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.4074939398631904	[916]	[920,1227,1586,1114]	7	hSpCas9	negative selection	9211289
147260710	147260733	6	+	27260156	TOV112D	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.356631710941649	[1289]	[1430,2401,1555,1397]	6	hSpCas9	negative selection	9211290
147260639	147260662	6	-	27260156	TOV112D	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.0794541212407548	[813]	[926,1051,812,708]	1	hSpCas9	negative selection	9211291
147239237	147239260	6	-	27260156	TOV112D	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.480176707892934	[177]	[112,230,93,97]	-7	hSpCas9	negative selection	9275544
147239169	147239192	6	+	27260156	TOV112D	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.4147256659016072	[232]	[195,224,117,174]	-7	hSpCas9	negative selection	9275545
147262312	147262335	6	-	27260156	TOV112D	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.3701141760384097	[3219]	[2830,2624,2047,2531]	-6	hSpCas9	negative selection	9275546
147262336	147262359	6	-	27260156	TC71	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.49349136606478006	[916]	[1314,1312,1295,1630]	9	hSpCas9	negative selection	9332540
147260710	147260733	6	+	27260156	TC71	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.24730303947688204	[1289]	[1533,1760,1482,1804]	6	hSpCas9	negative selection	9332541
147260639	147260662	6	-	27260156	TC71	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.04119170321471566	[813]	[844,755,820,1190]	1	hSpCas9	negative selection	9332542
147239237	147239260	6	-	27260156	TC71	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.016205226310603837	[177]	[200,227,128,198]	0	hSpCas9	negative selection	9396795
147239169	147239192	6	+	27260156	TC71	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	-0.3831924233065087	[232]	[180,158,211,214]	-8	hSpCas9	negative selection	9396796
147262312	147262335	6	-	27260156	TC71	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.4389136534842697	[3219]	[2477,2380,2552,2788]	-8	hSpCas9	negative selection	9396797
147262336	147262359	6	-	27260156	TC32	viability	TCTACCTTTCCCTCGTCCATTGG	STXBP5	ENSG00000164506	0.2645223579154009	[916]	[1059,639,1302,1284]	5	hSpCas9	negative selection	9453791
147260710	147260733	6	+	27260156	TC32	viability	TCTCAGGCTACGTCATTATGTGG	STXBP5	ENSG00000164506	0.19276904942279782	[1289]	[1332,884,1810,1722]	3	hSpCas9	negative selection	9453792
147260639	147260662	6	-	27260156	TC32	viability	CCACATAGAGCCACTTACTCTGG	STXBP5	ENSG00000164506	0.07432310723468949	[813]	[748,419,1380,885]	1	hSpCas9	negative selection	9453793
147239237	147239260	6	-	27260156	TC32	viability	AAATTTAAGCGAATGTAGTATGG	STXBP5	ENSG00000164506	-0.049829229437237554	[177]	[188,131,124,192]	-1	hSpCas9	negative selection	9518046
147239169	147239192	6	+	27260156	TC32	viability	GGGAGCGCTTGTGAGTGCCTTGG	STXBP5	ENSG00000164506	0.11473232402380895	[232]	[309,145,271,236]	2	hSpCas9	negative selection	9518047
147262312	147262335	6	-	27260156	TC32	viability	TTATCACTTATATGGACCACAGG	STXBP5	ENSG00000164506	-0.3858653204659559	[3219]	[1986,1778,3290,2493]	-6	hSpCas9	negative selection	9518048
147204609	147204632	6	+	27869803	HPAFII	viability after 27 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	0.4975615635584454	[351]	[431,118,NaN]	4	hSpCas9	negative selection	9593959
147205962	147205985	6	+	27869803	HPAFII	viability after 27 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	0.3282911721554455	[321]	[319,122,NaN]	2	hSpCas9	negative selection	9593960
147235307	147235330	6	-	27869803	HPAFII	viability after 27 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	1.42441862257012	[156]	[148,281,NaN]	9	hSpCas9	negative selection	9593961
147260652	147260675	6	+	27869803	HPAFII	viability after 27 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.07575576631196634	[1042]	[872,331,NaN]	0	hSpCas9	negative selection	9593962
147262332	147262355	6	+	27869803	HPAFII	viability after 27 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.08238625883507594	[186]	[78,124,NaN]	0	hSpCas9	negative selection	9593963
147278086	147278109	6	-	27869803	HPAFII	viability after 27 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	1.33340783091443	[224]	[254,333,NaN]	9	hSpCas9	negative selection	9593964
147204609	147204632	6	+	27869803	HPAFII	viability after 15 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.06358818056846688	[351]	[636,190,NaN]	0	hSpCas9	negative selection	9676408
147205962	147205985	6	+	27869803	HPAFII	viability after 15 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	-0.15440727746584637	[321]	[535,170,NaN]	-2	hSpCas9	negative selection	9676409
147235307	147235330	6	-	27869803	HPAFII	viability after 15 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	0.8638484842976236	[156]	[385,257,NaN]	8	hSpCas9	negative selection	9676410
147260652	147260675	6	+	27869803	HPAFII	viability after 15 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	-0.20752729290137606	[1042]	[1595,581,NaN]	-2	hSpCas9	negative selection	9676411
147262332	147262355	6	+	27869803	HPAFII	viability after 15 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	-0.1325944154749959	[186]	[289,116,NaN]	-1	hSpCas9	negative selection	9676412
147278086	147278109	6	-	27869803	HPAFII	viability after 15 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.6301404898431863	[224]	[475,310,NaN]	7	hSpCas9	negative selection	9676413
147204609	147204632	6	+	27869803	ASPC1	viability after 36 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	-0.04813165142277842	[980]	[162,413,379]	0	hSpCas9	negative selection	9758857
147205962	147205985	6	+	27869803	ASPC1	viability after 36 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	-0.5640598491325801	[748]	[185,38,277]	-5	hSpCas9	negative selection	9758858
147235307	147235330	6	-	27869803	ASPC1	viability after 36 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	-0.3314247017014439	[489]	[296,26,107]	-3	hSpCas9	negative selection	9758859
147260652	147260675	6	+	27869803	ASPC1	viability after 36 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	-0.13133067744042637	[2402]	[988,847,535]	-1	hSpCas9	negative selection	9758860
147262332	147262355	6	+	27869803	ASPC1	viability after 36 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	-0.41264833246357346	[402]	[127,160,44]	-4	hSpCas9	negative selection	9758861
147278086	147278109	6	-	27869803	ASPC1	viability after 36 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.3789570495959551	[595]	[96,255,400]	4	hSpCas9	negative selection	9758862
147204609	147204632	6	+	27869803	PATU8988S	viability after 35 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	0.1768358071685946	[804]	[362,369,NaN]	2	hSpCas9	negative selection	9841306
147205962	147205985	6	+	27869803	PATU8988S	viability after 35 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	-0.3666032066183823	[646]	[248,154,NaN]	-4	hSpCas9	negative selection	9841307
147235307	147235330	6	-	27869803	PATU8988S	viability after 35 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	0.2904000955562074	[478]	[206,264,NaN]	3	hSpCas9	negative selection	9841308
147260652	147260675	6	+	27869803	PATU8988S	viability after 35 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.3091918158800111	[2039]	[1011,1023,NaN]	3	hSpCas9	negative selection	9841309
147262332	147262355	6	+	27869803	PATU8988S	viability after 35 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.2065808292946042	[297]	[136,139,NaN]	2	hSpCas9	negative selection	9841310
147278086	147278109	6	-	27869803	PATU8988S	viability after 35 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.13579249914341907	[562]	[304,192,NaN]	1	hSpCas9	negative selection	9841311
147204609	147204632	6	+	27869803	PATU8988S	viability after 31 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	0.34580699497218204	[804]	[271,580,NaN]	4	hSpCas9	negative selection	9923755
147205962	147205985	6	+	27869803	PATU8988S	viability after 31 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	0.13595212624248335	[646]	[286,278,NaN]	1	hSpCas9	negative selection	9923756
147235307	147235330	6	-	27869803	PATU8988S	viability after 31 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	0.43705501230003807	[478]	[163,378,NaN]	5	hSpCas9	negative selection	9923757
147260652	147260675	6	+	27869803	PATU8988S	viability after 31 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.5404421320051649	[2039]	[974,1447,NaN]	6	hSpCas9	negative selection	9923758
147262332	147262355	6	+	27869803	PATU8988S	viability after 31 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.12303292781744024	[297]	[146,106,NaN]	1	hSpCas9	negative selection	9923759
147278086	147278109	6	-	27869803	PATU8988S	viability after 31 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	0.07019103154027015	[562]	[258,205,NaN]	0	hSpCas9	negative selection	9923760
147204609	147204632	6	+	27869803	HPAFII	viability after 35 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	0.9670416841150727	[351]	[456,225,NaN]	6	hSpCas9	negative selection	10006204
147205962	147205985	6	+	27869803	HPAFII	viability after 35 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	-0.005181754145238027	[321]	[192,127,NaN]	0	hSpCas9	negative selection	10006205
147235307	147235330	6	-	27869803	HPAFII	viability after 35 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	1.2164121488985813	[156]	[147,225,NaN]	7	hSpCas9	negative selection	10006206
147260652	147260675	6	+	27869803	HPAFII	viability after 35 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.45684375004709876	[1042]	[989,425,NaN]	3	hSpCas9	negative selection	10006207
147262332	147262355	6	+	27869803	HPAFII	viability after 35 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.3275179180237093	[186]	[59,184,NaN]	2	hSpCas9	negative selection	10006208
147278086	147278109	6	-	27869803	HPAFII	viability after 35 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	1.4420937487642642	[224]	[245,380,NaN]	8	hSpCas9	negative selection	10006209
147204609	147204632	6	+	27869803	HPAFII	viability after 31 days	AGCAGCATCCGCCTGGGAACCGG	STXBP5	ENSG00000164506	0.47118165117913524	[351]	[370,167,NaN]	3	hSpCas9	negative selection	10088653
147205962	147205985	6	+	27869803	HPAFII	viability after 31 days	CATCCCTAGACTGTTCGCCATGG	STXBP5	ENSG00000164506	-0.2699641139654534	[321]	[213,79,NaN]	-2	hSpCas9	negative selection	10088654
147235307	147235330	6	-	27869803	HPAFII	viability after 31 days	CATTAATCAGGAACTGGAGCTGG	STXBP5	ENSG00000164506	1.50007610817994	[156]	[231,267,NaN]	9	hSpCas9	negative selection	10088655
147260652	147260675	6	+	27869803	HPAFII	viability after 31 days	CTCTATGTGGGCACTGAACGAGG	STXBP5	ENSG00000164506	0.3125884361252602	[1042]	[1049,374,NaN]	2	hSpCas9	negative selection	10088656
147262332	147262355	6	+	27869803	HPAFII	viability after 31 days	TAATCCAATGGACGAGGGAAAGG	STXBP5	ENSG00000164506	0.34276607601051706	[186]	[56,215,NaN]	2	hSpCas9	negative selection	10088657
147278086	147278109	6	-	27869803	HPAFII	viability after 31 days	CATGATGCCAAGCAACAGAGTGG	STXBP5	ENSG00000164506	1.3674960601605737	[224]	[276,378,NaN]	8	hSpCas9	negative selection	10088658
147204535	147204558	6	+	28162770	P31FUJ	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	0.8105252272497221	[81]	[168]	8	hSpCas9	negative selection	10245113
147239186	147239209	6	-	28162770	P31FUJ	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	-0.16498682018680705	[186]	[195]	-2	hSpCas9	negative selection	10245114
147262288	147262311	6	+	28162770	P31FUJ	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.11664695323688856	[134]	[171]	1	hSpCas9	negative selection	10245115
147313996	147314019	6	+	28162770	P31FUJ	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	0.7024921061978062	[56]	[108]	7	hSpCas9	negative selection	10245116
147314261	147314284	6	+	28162770	P31FUJ	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.5427662289755747	[412]	[706]	6	hSpCas9	negative selection	10245117
147316258	147316281	6	+	28162770	P31FUJ	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-0.9246799090520468	[20]	[12]	-6	hSpCas9	negative selection	10245118
147316337	147316360	6	-	28162770	P31FUJ	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-0.45254309947442206	[452]	[388]	-4	hSpCas9	negative selection	10245119
147373764	147373787	6	+	28162770	P31FUJ	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	0.3634756095346116	[126]	[191]	4	hSpCas9	negative selection	10245120
147204557	147204580	6	+	28162770	P31FUJ	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	0.10306508143085746	[102]	[129]	1	hSpCas9	negative selection	10245121
147205979	147206002	6	-	28162770	P31FUJ	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.24654226104068105	[210]	[208]	-2	hSpCas9	negative selection	10245122
147204535	147204558	6	+	28162770	TF1	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10414479
147239186	147239209	6	-	28162770	TF1	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10414480
147262288	147262311	6	+	28162770	TF1	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	NaN	[NaN]	[128]	1	hSpCas9	negative selection	10414481
147313996	147314019	6	+	28162770	TF1	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10414482
147314261	147314284	6	+	28162770	TF1	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	NaN	[NaN]	[248]	1	hSpCas9	negative selection	10414483
147316258	147316281	6	+	28162770	TF1	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10414484
147316337	147316360	6	-	28162770	TF1	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	NaN	[NaN]	[178]	1	hSpCas9	negative selection	10414485
147373764	147373787	6	+	28162770	TF1	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10414486
147204557	147204580	6	+	28162770	TF1	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10414487
147205979	147206002	6	-	28162770	TF1	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	NaN	[NaN]	[88]	1	hSpCas9	negative selection	10414488
147204535	147204558	6	+	28162770	SKM1	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	1.8333501305905486	[19]	[125]	9	hSpCas9	negative selection	10583845
147239186	147239209	6	-	28162770	SKM1	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	1.212486678363285	[30]	[126]	9	hSpCas9	negative selection	10583846
147262288	147262311	6	+	28162770	SKM1	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.7927081460932028	[31]	[97]	7	hSpCas9	negative selection	10583847
147313996	147314019	6	+	28162770	SKM1	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	-0.9289169019385173	[13]	[12]	-6	hSpCas9	negative selection	10583848
147314261	147314284	6	+	28162770	SKM1	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.4088821842080821	[120]	[283]	4	hSpCas9	negative selection	10583849
147316258	147316281	6	+	28162770	SKM1	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-0.1699250014423126	[6]	[10]	-1	hSpCas9	negative selection	10583850
147316337	147316360	6	-	28162770	SKM1	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-0.5224414161630977	[129]	[159]	-4	hSpCas9	negative selection	10583851
147373764	147373787	6	+	28162770	SKM1	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	-0.2640062449011187	[35]	[52]	-2	hSpCas9	negative selection	10583852
147204557	147204580	6	+	28162770	SKM1	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	-0.2694606749932269	[14]	[21]	-2	hSpCas9	negative selection	10583853
147205979	147206002	6	-	28162770	SKM1	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.7083449162264384	[60]	[65]	-5	hSpCas9	negative selection	10583854
147204535	147204558	6	+	28162770	SKM1	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	1.8333501305905486	[19]	[125]	9	hSpCas9	negative selection	10753211
147239186	147239209	6	-	28162770	SKM1	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	1.212486678363285	[30]	[126]	9	hSpCas9	negative selection	10753212
147262288	147262311	6	+	28162770	SKM1	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.7927081460932028	[31]	[97]	7	hSpCas9	negative selection	10753213
147313996	147314019	6	+	28162770	SKM1	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	-0.9289169019385173	[13]	[12]	-6	hSpCas9	negative selection	10753214
147314261	147314284	6	+	28162770	SKM1	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.4088821842080821	[120]	[283]	4	hSpCas9	negative selection	10753215
147316258	147316281	6	+	28162770	SKM1	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-0.1699250014423126	[6]	[10]	-1	hSpCas9	negative selection	10753216
147316337	147316360	6	-	28162770	SKM1	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-0.5224414161630977	[129]	[159]	-4	hSpCas9	negative selection	10753217
147373764	147373787	6	+	28162770	SKM1	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	-0.2640062449011187	[35]	[52]	-2	hSpCas9	negative selection	10753218
147204557	147204580	6	+	28162770	SKM1	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	-0.2694606749932269	[14]	[21]	-2	hSpCas9	negative selection	10753219
147205979	147206002	6	-	28162770	SKM1	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.7083449162264384	[60]	[65]	-5	hSpCas9	negative selection	10753220
147204535	147204558	6	+	28162770	PL21	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	0.6765776584323071	[114]	[79]	6	hSpCas9	negative selection	10922577
147239186	147239209	6	-	28162770	PL21	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	-0.05676868854763234	[140]	[58]	0	hSpCas9	negative selection	10922578
147262288	147262311	6	+	28162770	PL21	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.7032018615653881	[150]	[106]	6	hSpCas9	negative selection	10922579
147313996	147314019	6	+	28162770	PL21	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	-0.09942066736958766	[63]	[25]	0	hSpCas9	negative selection	10922580
147314261	147314284	6	+	28162770	PL21	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	-0.3848228862318359	[401]	[133]	-3	hSpCas9	negative selection	10922581
147316258	147316281	6	+	28162770	PL21	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	2.0074945365469237	[15]	[27]	9	hSpCas9	negative selection	10922582
147316337	147316360	6	-	28162770	PL21	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-1.5816802154611465	[391]	[56]	-7	hSpCas9	negative selection	10922583
147373764	147373787	6	+	28162770	PL21	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	0.035752796588437885	[64]	[28]	0	hSpCas9	negative selection	10922584
147204557	147204580	6	+	28162770	PL21	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	0.16061125030268264	[73]	[35]	1	hSpCas9	negative selection	10922585
147205979	147206002	6	-	28162770	PL21	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.11720121090239038	[156]	[62]	-1	hSpCas9	negative selection	10922586
147204535	147204558	6	+	28162770	P31FUJ	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	0.8105252272497221	[81]	[168]	8	hSpCas9	negative selection	11091943
147239186	147239209	6	-	28162770	P31FUJ	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	-0.16498682018680705	[186]	[195]	-2	hSpCas9	negative selection	11091944
147262288	147262311	6	+	28162770	P31FUJ	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.11664695323688856	[134]	[171]	1	hSpCas9	negative selection	11091945
147313996	147314019	6	+	28162770	P31FUJ	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	0.7024921061978062	[56]	[108]	7	hSpCas9	negative selection	11091946
147314261	147314284	6	+	28162770	P31FUJ	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.5427662289755747	[412]	[706]	6	hSpCas9	negative selection	11091947
147316258	147316281	6	+	28162770	P31FUJ	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-0.9246799090520468	[20]	[12]	-6	hSpCas9	negative selection	11091948
147316337	147316360	6	-	28162770	P31FUJ	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-0.45254309947442206	[452]	[388]	-4	hSpCas9	negative selection	11091949
147373764	147373787	6	+	28162770	P31FUJ	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	0.3634756095346116	[126]	[191]	4	hSpCas9	negative selection	11091950
147204557	147204580	6	+	28162770	P31FUJ	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	0.10306508143085746	[102]	[129]	1	hSpCas9	negative selection	11091951
147205979	147206002	6	-	28162770	P31FUJ	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.24654226104068105	[210]	[208]	-2	hSpCas9	negative selection	11091952
147204535	147204558	6	+	28162770	OCIAML5	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	0.36047806451610365	[62]	[145]	3	hSpCas9	negative selection	11261309
147239186	147239209	6	-	28162770	OCIAML5	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	0.31566087487406946	[72]	[163]	2	hSpCas9	negative selection	11261310
147262288	147262311	6	+	28162770	OCIAML5	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	1.7262012772831508	[35]	[214]	9	hSpCas9	negative selection	11261311
147313996	147314019	6	+	28162770	OCIAML5	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	-0.8023135356668973	[56]	[58]	-5	hSpCas9	negative selection	11261312
147314261	147314284	6	+	28162770	OCIAML5	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	1.1103502463278465	[174]	[681]	8	hSpCas9	negative selection	11261313
147316258	147316281	6	+	28162770	OCIAML5	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	1.1479334291360033	[8]	[35]	8	hSpCas9	negative selection	11261314
147316337	147316360	6	-	28162770	OCIAML5	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-1.484557441667739	[323]	[208]	-7	hSpCas9	negative selection	11261315
147373764	147373787	6	+	28162770	OCIAML5	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	1.56826522808436	[50]	[272]	9	hSpCas9	negative selection	11261316
147204557	147204580	6	+	28162770	OCIAML5	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	1.0673149689277184	[45]	[173]	8	hSpCas9	negative selection	11261317
147205979	147206002	6	-	28162770	OCIAML5	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	0.0654712689440299	[125]	[237]	0	hSpCas9	negative selection	11261318
147204535	147204558	6	+	28162770	EOL1	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	0.5071852193454467	[206]	[154]	4	hSpCas9	negative selection	11430675
147239186	147239209	6	-	28162770	EOL1	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	0.04450839561144726	[172]	[93]	0	hSpCas9	negative selection	11430676
147262288	147262311	6	+	28162770	EOL1	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.9192920461190395	[274]	[273]	7	hSpCas9	negative selection	11430677
147313996	147314019	6	+	28162770	EOL1	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	0.14467358593503743	[90]	[52]	1	hSpCas9	negative selection	11430678
147314261	147314284	6	+	28162770	EOL1	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	-0.15447222763060364	[787]	[372]	-1	hSpCas9	negative selection	11430679
147316258	147316281	6	+	28162770	EOL1	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-1.5160248198154473	[37]	[6]	-7	hSpCas9	negative selection	11430680
147316337	147316360	6	-	28162770	EOL1	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-1.663083915926606	[540]	[89]	-8	hSpCas9	negative selection	11430681
147373764	147373787	6	+	28162770	EOL1	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	0.024711933495966454	[152]	[81]	0	hSpCas9	negative selection	11430682
147204557	147204580	6	+	28162770	EOL1	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	-0.12889148739092593	[109]	[52]	-1	hSpCas9	negative selection	11430683
147205979	147206002	6	-	28162770	EOL1	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.38455628295924427	[279]	[112]	-3	hSpCas9	negative selection	11430684
147204535	147204558	6	+	28162770	MOLM13	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	1.0947655239991294	[146]	[226]	8	hSpCas9	negative selection	11600041
147239186	147239209	6	-	28162770	MOLM13	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	0.12791483123976294	[180]	[142]	0	hSpCas9	negative selection	11600042
147262288	147262311	6	+	28162770	MOLM13	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	1.327841421436882	[226]	[411]	8	hSpCas9	negative selection	11600043
147313996	147314019	6	+	28162770	MOLM13	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	0.9882798809696511	[98]	[141]	7	hSpCas9	negative selection	11600044
147314261	147314284	6	+	28162770	MOLM13	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.24196310653457032	[544]	[465]	1	hSpCas9	negative selection	11600045
147316258	147316281	6	+	28162770	MOLM13	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-2.9915422370927187	[21]	[1]	-8	hSpCas9	negative selection	11600046
147316337	147316360	6	-	28162770	MOLM13	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-0.4335948778143529	[565]	[302]	-3	hSpCas9	negative selection	11600047
147373764	147373787	6	+	28162770	MOLM13	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	0.8499764590221363	[154]	[201]	6	hSpCas9	negative selection	11600048
147204557	147204580	6	+	28162770	MOLM13	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	-0.47071007379127794	[91]	[47]	-3	hSpCas9	negative selection	11600049
147205979	147206002	6	-	28162770	MOLM13	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	0.7079838046144857	[242]	[286]	5	hSpCas9	negative selection	11600050
147204535	147204558	6	+	28162770	HEL	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	0.8985777364299468	[133]	[159]	7	hSpCas9	negative selection	11769407
147239186	147239209	6	-	28162770	HEL	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	0.09959650697382771	[152]	[104]	0	hSpCas9	negative selection	11769408
147262288	147262311	6	+	28162770	HEL	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.4291433589010679	[217]	[187]	3	hSpCas9	negative selection	11769409
147313996	147314019	6	+	28162770	HEL	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	0.1605871368629761	[87]	[62]	1	hSpCas9	negative selection	11769410
147314261	147314284	6	+	28162770	HEL	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.8248532424505832	[549]	[623]	7	hSpCas9	negative selection	11769411
147316258	147316281	6	+	28162770	HEL	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	0.5432031584494426	[14]	[13]	4	hSpCas9	negative selection	11769412
147316337	147316360	6	-	28162770	HEL	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	0.0816795178056875	[418]	[283]	0	hSpCas9	negative selection	11769413
147373764	147373787	6	+	28162770	HEL	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	0.12816565917059863	[109]	[76]	1	hSpCas9	negative selection	11769414
147204557	147204580	6	+	28162770	HEL	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	-1.4161548570532114	[74]	[17]	-7	hSpCas9	negative selection	11769415
147205979	147206002	6	-	28162770	HEL	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.7789623975594976	[216]	[80]	-5	hSpCas9	negative selection	11769416
147204535	147204558	6	+	28162770	MV411	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	0.2280722259158443	[74]	[73]	2	hSpCas9	negative selection	11938773
147239186	147239209	6	-	28162770	MV411	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	0.9921804955407009	[73]	[123]	8	hSpCas9	negative selection	11938774
147262288	147262311	6	+	28162770	MV411	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	1.2779396391801194	[116]	[238]	9	hSpCas9	negative selection	11938775
147313996	147314019	6	+	28162770	MV411	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	-0.0797271924707339	[68]	[54]	0	hSpCas9	negative selection	11938776
147314261	147314284	6	+	28162770	MV411	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.3672773207887785	[380]	[413]	3	hSpCas9	negative selection	11938777
147316258	147316281	6	+	28162770	MV411	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-0.5826374477749123	[15]	[8]	-4	hSpCas9	negative selection	11938778
147316337	147316360	6	-	28162770	MV411	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-0.6389056674216576	[365]	[197]	-4	hSpCas9	negative selection	11938779
147373764	147373787	6	+	28162770	MV411	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	1.4458511091847834	[77]	[178]	9	hSpCas9	negative selection	11938780
147204557	147204580	6	+	28162770	MV411	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	-1.1494526017858093	[78]	[29]	-6	hSpCas9	negative selection	11938781
147205979	147206002	6	-	28162770	MV411	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	0.46458951942334314	[196]	[228]	4	hSpCas9	negative selection	11938782
147204535	147204558	6	+	28162770	MONOMAC1	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	0.942237941542574	[73]	[162]	8	hSpCas9	negative selection	12108139
147239186	147239209	6	-	28162770	MONOMAC1	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	-0.3995297109582969	[83]	[72]	-3	hSpCas9	negative selection	12108140
147262288	147262311	6	+	28162770	MONOMAC1	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	1.108949703958787	[90]	[224]	8	hSpCas9	negative selection	12108141
147313996	147314019	6	+	28162770	MONOMAC1	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	-0.559606926444262	[44]	[34]	-5	hSpCas9	negative selection	12108142
147314261	147314284	6	+	28162770	MONOMAC1	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.2958500687632233	[247]	[348]	3	hSpCas9	negative selection	12108143
147316258	147316281	6	+	28162770	MONOMAC1	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-0.7819993477807099	[23]	[15]	-6	hSpCas9	negative selection	12108144
147316337	147316360	6	-	28162770	MONOMAC1	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-1.0450337536145038	[305]	[169]	-7	hSpCas9	negative selection	12108145
147373764	147373787	6	+	28162770	MONOMAC1	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	-1.6299962543356596	[53]	[19]	-8	hSpCas9	negative selection	12108146
147204557	147204580	6	+	28162770	MONOMAC1	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	1.344533058148222	[44]	[130]	9	hSpCas9	negative selection	12108147
147205979	147206002	6	-	28162770	MONOMAC1	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.4848391580422898	[93]	[76]	-4	hSpCas9	negative selection	12108148
147204535	147204558	6	+	28162770	OCIAML2	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	0.7809089417538031	[20]	[199]	7	hSpCas9	negative selection	12277505
147239186	147239209	6	-	28162770	OCIAML2	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	1.0639591529638754	[16]	[196]	8	hSpCas9	negative selection	12277506
147262288	147262311	6	+	28162770	OCIAML2	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.2563516803514228	[28]	[191]	2	hSpCas9	negative selection	12277507
147313996	147314019	6	+	28162770	OCIAML2	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	-0.6863585162975983	[8]	[30]	-5	hSpCas9	negative selection	12277508
147314261	147314284	6	+	28162770	OCIAML2	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.7517625960942869	[83]	[783]	7	hSpCas9	negative selection	12277509
147316258	147316281	6	+	28162770	OCIAML2	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	-1.0111982066048641	[3]	[10]	-6	hSpCas9	negative selection	12277510
147316337	147316360	6	-	28162770	OCIAML2	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-1.8185531286624683	[76]	[120]	-8	hSpCas9	negative selection	12277511
147373764	147373787	6	+	28162770	OCIAML2	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	0.09124906236595365	[20]	[123]	0	hSpCas9	negative selection	12277512
147204557	147204580	6	+	28162770	OCIAML2	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	-1.2482374039057134	[11]	[27]	-7	hSpCas9	negative selection	12277513
147205979	147206002	6	-	28162770	OCIAML2	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-1.1657752437137403	[33]	[83]	-6	hSpCas9	negative selection	12277514
147204535	147204558	6	+	28162770	OCIAML3	viability	GAGGAAATTCAACATCAGGAAGG	STXBP5	ENSG00000164506	-0.04511439431052866	[26]	[78]	0	hSpCas9	negative selection	12446871
147239186	147239209	6	-	28162770	OCIAML3	viability	GTGTAAGGTGTCATCAGCCAAGG	STXBP5	ENSG00000164506	0.9701963002301957	[34]	[206]	8	hSpCas9	negative selection	12446872
147262288	147262311	6	+	28162770	OCIAML3	viability	AGGTCATCTAAATCTCACCCAGG	STXBP5	ENSG00000164506	0.5835305452280243	[41]	[189]	5	hSpCas9	negative selection	12446873
147313996	147314019	6	+	28162770	OCIAML3	viability	GGAGCTAGACAGAAACGTCAAGG	STXBP5	ENSG00000164506	1.853451336647058	[10]	[119]	9	hSpCas9	negative selection	12446874
147314261	147314284	6	+	28162770	OCIAML3	viability	TAGGAATGGCCCATCAACGGAGG	STXBP5	ENSG00000164506	0.47999294111961355	[113]	[479]	4	hSpCas9	negative selection	12446875
147316258	147316281	6	+	28162770	OCIAML3	viability	AAATGATGTGGAAACTCCGGAGG	STXBP5	ENSG00000164506	1.4059923596758375	[1]	[15]	9	hSpCas9	negative selection	12446876
147316337	147316360	6	-	28162770	OCIAML3	viability	GTAGATGGATGAGACTGAGGAGG	STXBP5	ENSG00000164506	-0.4750665676006557	[127]	[277]	-4	hSpCas9	negative selection	12446877
147373764	147373787	6	+	28162770	OCIAML3	viability	ACACCTGAAGCACCAAACAGGGG	STXBP5	ENSG00000164506	-0.2914448703037318	[29]	[73]	-2	hSpCas9	negative selection	12446878
147204557	147204580	6	+	28162770	OCIAML3	viability	GTGCTGGACGGCCTGACCGCCGG	STXBP5	ENSG00000164506	2.679010854082253	[17]	[347]	9	hSpCas9	negative selection	12446879
147205979	147206002	6	-	28162770	OCIAML3	viability	AGGGTTGATAGGGAAATCCATGG	STXBP5	ENSG00000164506	-0.40958306918673587	[43]	[99]	-3	hSpCas9	negative selection	12446880