Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:23451
• Symbol:Sf3b1
• Description:splicing factor 3b subunit 1

DataSource: http://genomecrispr.dkfz.de/#!/results/Sf3b1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
197434971	197434994	2	-	26472758	Jiyoye	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-6.535339123833366	[122]	[0]	-9	hSpCas9	negative selection	145424
197423944	197423967	2	-	26472758	Jiyoye	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	-0.3440040718800336	[169]	[100]	-2	hSpCas9	negative selection	145425
197423914	197423937	2	-	26472758	Jiyoye	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-3.052256237131424	[10]	[0]	-9	hSpCas9	negative selection	145426
197420433	197420456	2	+	26472758	Jiyoye	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-0.6434506915640945	[28]	[13]	-4	hSpCas9	negative selection	145427
197421064	197421087	2	-	26472758	Jiyoye	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.604999332440229	[237]	[58]	-8	hSpCas9	negative selection	145428
197420514	197420537	2	+	26472758	Jiyoye	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-0.129578026172663	[102]	[70]	-1	hSpCas9	negative selection	145429
197423845	197423868	2	-	26472758	Jiyoye	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.9730290592793249	[151]	[224]	6	hSpCas9	negative selection	145430
197421050	197421073	2	+	26472758	Jiyoye	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-4.570104541994043	[440]	[13]	-9	hSpCas9	negative selection	145431
197420498	197420521	2	-	26472758	Jiyoye	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-5.821643308990008	[74]	[0]	-9	hSpCas9	negative selection	145432
197420447	197420470	2	+	26472758	Jiyoye	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	0.21453030356347752	[103]	[90]	1	hSpCas9	negative selection	145433
197434971	197434994	2	-	26472758	KBM7	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.6504879575816056	[194,275]	[7,26]	-9	hSpCas9	negative selection	336542
197423944	197423967	2	-	26472758	KBM7	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	-0.3923358889924009	[992,962]	[256,435]	-4	hSpCas9	negative selection	336543
197423914	197423937	2	-	26472758	KBM7	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-0.48495775593797097	[94,50]	[25,21]	-4	hSpCas9	negative selection	336544
197420433	197420456	2	+	26472758	KBM7	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	0.3092818915690485	[162,116]	[59,98]	3	hSpCas9	negative selection	336545
197421064	197421087	2	-	26472758	KBM7	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-0.7453146078398246	[1065,709]	[222,264]	-6	hSpCas9	negative selection	336546
197420514	197420537	2	+	26472758	KBM7	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-0.7270380285686415	[640,486]	[153,162]	-6	hSpCas9	negative selection	336547
197423845	197423868	2	-	26472758	KBM7	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.5256096524801255	[1046,892]	[674,635]	6	hSpCas9	negative selection	336548
197421050	197421073	2	+	26472758	KBM7	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-1.9950803266196504	[1066,868]	[93,130]	-8	hSpCas9	negative selection	336549
197420498	197420521	2	-	26472758	KBM7	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.022986275064293	[327,459]	[44,47]	-8	hSpCas9	negative selection	336550
197420447	197420470	2	+	26472758	KBM7	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	-0.22486987582529538	[370,168]	[104,104]	-2	hSpCas9	negative selection	336551
197434971	197434994	2	-	26472758	Raji	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-3.7874342279343445	[118]	[1]	-9	hSpCas9	negative selection	527660
197423944	197423967	2	-	26472758	Raji	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	-0.054254854883752146	[433]	[96]	0	hSpCas9	negative selection	527661
197423914	197423937	2	-	26472758	Raji	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	0.10738353537359924	[7]	[1]	1	hSpCas9	negative selection	527662
197420433	197420456	2	+	26472758	Raji	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-2.049120950306391	[106]	[5]	-8	hSpCas9	negative selection	527663
197421064	197421087	2	-	26472758	Raji	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.6285208634222963	[452]	[33]	-8	hSpCas9	negative selection	527664
197420514	197420537	2	+	26472758	Raji	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-0.8174289682321814	[242]	[31]	-6	hSpCas9	negative selection	527665
197423845	197423868	2	-	26472758	Raji	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.1677030046474114	[444]	[115]	1	hSpCas9	negative selection	527666
197421050	197421073	2	+	26472758	Raji	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-2.1912747801909154	[491]	[24]	-8	hSpCas9	negative selection	527667
197420498	197420521	2	-	26472758	Raji	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-1.7505974597539726	[144]	[9]	-8	hSpCas9	negative selection	527668
197420447	197420470	2	+	26472758	Raji	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	-1.4925293068135284	[193]	[15]	-8	hSpCas9	negative selection	527669
197434971	197434994	2	-	26472758	K562	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.10350457575386	[223]	[10]	-9	hSpCas9	negative selection	718778
197423944	197423967	2	-	26472758	K562	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	0.6850940641324764	[738]	[1002]	5	hSpCas9	negative selection	718779
197423914	197423937	2	-	26472758	K562	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	0.8796544348688267	[46]	[72]	7	hSpCas9	negative selection	718780
197420433	197420456	2	+	26472758	K562	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-6.31017012401119	[93]	[0]	-9	hSpCas9	negative selection	718781
197421064	197421087	2	-	26472758	K562	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.9530619962964268	[554]	[120]	-7	hSpCas9	negative selection	718782
197420514	197420537	2	+	26472758	K562	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-1.8120684636800264	[598]	[143]	-7	hSpCas9	negative selection	718783
197423845	197423868	2	-	26472758	K562	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	1.027111595489782	[707]	[1217]	8	hSpCas9	negative selection	718784
197421050	197421073	2	+	26472758	K562	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-0.4349285820150859	[678]	[423]	-3	hSpCas9	negative selection	718785
197420498	197420521	2	-	26472758	K562	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-3.6315400083901808	[322]	[21]	-9	hSpCas9	negative selection	718786
197420447	197420470	2	+	26472758	K562	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	-0.6219981179549613	[267]	[146]	-4	hSpCas9	negative selection	718787
197408527	197408550	2	-	26627737	DLD1	viability	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-0.2532183170261555	[131]	[35,45,23]	-3	hSpCas9	negative selection	809782
197409984	197410007	2	+	26627737	DLD1	viability	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-3.8631188554592835	[427]	[9,10,6]	-9	hSpCas9	negative selection	809783
197420498	197420521	2	-	26627737	DLD1	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-3.350799284768546	[204]	[4,13,0]	-9	hSpCas9	negative selection	809784
197421081	197421104	2	-	26627737	DLD1	viability	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.2696322778794955	[399]	[51,59,44]	-8	hSpCas9	negative selection	809785
197423909	197423932	2	-	26627737	DLD1	viability	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-1.3026973016428813	[239]	[14,40,34]	-8	hSpCas9	negative selection	809786
197434971	197434994	2	-	26627737	DLD1	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-5.460898682175533	[445]	[1,6,0]	-9	hSpCas9	negative selection	809787
197408527	197408550	2	-	26627737	GBM cells	viability after 5 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-2.3864883439765627	[116]	[18,4]	-9	hSpCas9	negative selection	892097
197409984	197410007	2	+	26627737	GBM cells	viability after 5 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-2.598585784585131	[191]	[14,18]	-9	hSpCas9	negative selection	892098
197420498	197420521	2	-	26627737	GBM cells	viability after 5 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-1.8015258432554064	[155]	[33,13]	-9	hSpCas9	negative selection	892099
197421081	197421104	2	-	26627737	GBM cells	viability after 5 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	0.37133359630049845	[190]	[160,103]	5	hSpCas9	negative selection	892100
197423909	197423932	2	-	26627737	GBM cells	viability after 5 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-2.5444340204165354	[222]	[15,24]	-9	hSpCas9	negative selection	892101
197434971	197434994	2	-	26627737	GBM cells	viability after 5 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-5.89550199146442	[221]	[0,2]	-9	hSpCas9	negative selection	892102
197408527	197408550	2	-	26627737	GBM cells	viability after 13 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-1.6489355426597356	[116]	[22,17]	-9	hSpCas9	negative selection	974412
197409984	197410007	2	+	26627737	GBM cells	viability after 13 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-3.4360728364478073	[191]	[18,1]	-9	hSpCas9	negative selection	974413
197420498	197420521	2	-	26627737	GBM cells	viability after 13 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.3940467820456046	[155]	[14,16]	-9	hSpCas9	negative selection	974414
197421081	197421104	2	-	26627737	GBM cells	viability after 13 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	0.18596823314428734	[190]	[177,68]	2	hSpCas9	negative selection	974415
197423909	197423932	2	-	26627737	GBM cells	viability after 13 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-3.1220890984837615	[222]	[14,12]	-9	hSpCas9	negative selection	974416
197434971	197434994	2	-	26627737	GBM cells	viability after 13 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-6.912312742771658	[221]	[0,0]	-9	hSpCas9	negative selection	974417
197408527	197408550	2	-	26627737	GBM cells	viability after 21 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-1.4105221537407968	[116]	[25,21]	-8	hSpCas9	negative selection	1056727
197409984	197410007	2	+	26627737	GBM cells	viability after 21 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-6.704729201105498	[191]	[0,0]	-9	hSpCas9	negative selection	1056728
197420498	197420521	2	-	26627737	GBM cells	viability after 21 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-5.09612211565596	[155]	[2,1]	-9	hSpCas9	negative selection	1056729
197421081	197421104	2	-	26627737	GBM cells	viability after 21 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.5706631224911585	[190]	[72,66]	-5	hSpCas9	negative selection	1056730
197423909	197423932	2	-	26627737	GBM cells	viability after 21 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-2.093412120809337	[222]	[30,25]	-9	hSpCas9	negative selection	1056731
197434971	197434994	2	-	26627737	GBM cells	viability after 21 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-6.914182566734447	[221]	[0,0]	-9	hSpCas9	negative selection	1056732
197408527	197408550	2	-	26627737	RPE1	viability after 9 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-0.23468036381031032	[109]	[37,17]	-2	hSpCas9	negative selection	1139042
197409984	197410007	2	+	26627737	RPE1	viability after 9 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-0.5394095592556962	[397]	[45,136]	-4	hSpCas9	negative selection	1139043
197420498	197420521	2	-	26627737	RPE1	viability after 9 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-3.224713504797285	[502]	[1,35]	-9	hSpCas9	negative selection	1139044
197421081	197421104	2	-	26627737	RPE1	viability after 9 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.2974228271057828	[344]	[46,39]	-7	hSpCas9	negative selection	1139045
197423909	197423932	2	-	26627737	RPE1	viability after 9 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-1.6403820620843692	[860]	[68,108]	-8	hSpCas9	negative selection	1139046
197434971	197434994	2	-	26627737	RPE1	viability after 9 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.489368037278804	[384]	[0,10]	-9	hSpCas9	negative selection	1139047
197408527	197408550	2	-	26627737	RPE1	viability after 12 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-0.9893917565179802	[109]	[10,18]	-6	hSpCas9	negative selection	1221357
197409984	197410007	2	+	26627737	RPE1	viability after 12 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-0.6212756208770485	[397]	[69,68]	-4	hSpCas9	negative selection	1221358
197420498	197420521	2	-	26627737	RPE1	viability after 12 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.077015632271929	[502]	[15,48]	-8	hSpCas9	negative selection	1221359
197421081	197421104	2	-	26627737	RPE1	viability after 12 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.9442353359952775	[344]	[9,38]	-8	hSpCas9	negative selection	1221360
197423909	197423932	2	-	26627737	RPE1	viability after 12 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-2.384988532507073	[860]	[19,69]	-9	hSpCas9	negative selection	1221361
197434971	197434994	2	-	26627737	RPE1	viability after 12 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-6.692603223909126	[384]	[0,0]	-9	hSpCas9	negative selection	1221362
197408527	197408550	2	-	26627737	RPE1	viability after 15 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	0.3545443154684724	[109]	[79,0]	2	hSpCas9	negative selection	1303672
197409984	197410007	2	+	26627737	RPE1	viability after 15 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-1.2675973360058332	[397]	[31,60]	-7	hSpCas9	negative selection	1303673
197420498	197420521	2	-	26627737	RPE1	viability after 15 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-6.576433620317013	[502]	[1,0]	-9	hSpCas9	negative selection	1303674
197421081	197421104	2	-	26627737	RPE1	viability after 15 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.5516063153573112	[344]	[44,21]	-7	hSpCas9	negative selection	1303675
197423909	197423932	2	-	26627737	RPE1	viability after 15 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-3.3012057682275313	[860]	[12,35]	-9	hSpCas9	negative selection	1303676
197434971	197434994	2	-	26627737	RPE1	viability after 15 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-6.766965761710369	[384]	[0,0]	-9	hSpCas9	negative selection	1303677
197408527	197408550	2	-	26627737	RPE1	viability after 18 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-4.891691453423917	[109]	[0,0]	-9	hSpCas9	negative selection	1385987
197409984	197410007	2	+	26627737	RPE1	viability after 18 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-2.027186381539222	[397]	[21,30]	-8	hSpCas9	negative selection	1385988
197420498	197420521	2	-	26627737	RPE1	viability after 18 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-4.532049919197705	[502]	[1,9]	-9	hSpCas9	negative selection	1385989
197421081	197421104	2	-	26627737	RPE1	viability after 18 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.2462941998745813	[344]	[60,15]	-6	hSpCas9	negative selection	1385990
197423909	197423932	2	-	26627737	RPE1	viability after 18 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-2.372608749218208	[860]	[40,48]	-8	hSpCas9	negative selection	1385991
197434971	197434994	2	-	26627737	RPE1	viability after 18 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-6.699046375481521	[384]	[0,0]	-9	hSpCas9	negative selection	1385992
197408527	197408550	2	-	26627737	HeLa	viability after 8 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-1.0903315552717867	[44]	[21,7,0]	-8	hSpCas9	negative selection	1468302
197409984	197410007	2	+	26627737	HeLa	viability after 8 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	2.083958104842613	[42]	[56,154,24]	9	hSpCas9	negative selection	1468303
197420498	197420521	2	-	26627737	HeLa	viability after 8 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-3.534588592459745	[542]	[37,5,20]	-9	hSpCas9	negative selection	1468304
197421081	197421104	2	-	26627737	HeLa	viability after 8 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	0.4580218795345329	[319]	[149,182,228]	4	hSpCas9	negative selection	1468305
197423909	197423932	2	-	26627737	HeLa	viability after 8 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-2.1351916522051226	[217]	[59,2,10]	-9	hSpCas9	negative selection	1468306
197434971	197434994	2	-	26627737	HeLa	viability after 8 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.6059871588703416	[287]	[25,31,5]	-9	hSpCas9	negative selection	1468307
197408527	197408550	2	-	26627737	HeLa	viability after 12 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-1.9579732234988292	[44]	[12,0,0]	-9	hSpCas9	negative selection	1550617
197409984	197410007	2	+	26627737	HeLa	viability after 12 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	2.003753187280457	[42]	[165,0,56]	9	hSpCas9	negative selection	1550618
197420498	197420521	2	-	26627737	HeLa	viability after 12 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-1.2989567879495958	[542]	[152,94,26]	-8	hSpCas9	negative selection	1550619
197421081	197421104	2	-	26627737	HeLa	viability after 12 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	0.13043353606946242	[319]	[83,158,187]	1	hSpCas9	negative selection	1550620
197423909	197423932	2	-	26627737	HeLa	viability after 12 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.9744015784767021	[217]	[8,40,86]	-7	hSpCas9	negative selection	1550621
197434971	197434994	2	-	26627737	HeLa	viability after 12 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.6307970972120827	[287]	[11,33,68]	-9	hSpCas9	negative selection	1550622
197408527	197408550	2	-	26627737	HeLa	viability after 15 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-0.06168316142815389	[44]	[47,1,0]	0	hSpCas9	negative selection	1632932
197409984	197410007	2	+	26627737	HeLa	viability after 15 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	0.005211151792459123	[42]	[26,2,22]	0	hSpCas9	negative selection	1632933
197420498	197420521	2	-	26627737	HeLa	viability after 15 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.238864872010614	[542]	[56,52,28]	-9	hSpCas9	negative selection	1632934
197421081	197421104	2	-	26627737	HeLa	viability after 15 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	0.5177995391728517	[319]	[139,138,288]	4	hSpCas9	negative selection	1632935
197423909	197423932	2	-	26627737	HeLa	viability after 15 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.45093949570247494	[217]	[6,141,44]	-4	hSpCas9	negative selection	1632936
197434971	197434994	2	-	26627737	HeLa	viability after 15 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.5244721451639403	[287]	[27,0,32]	-9	hSpCas9	negative selection	1632937
197408527	197408550	2	-	26627737	HeLa	viability after 18 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	0.03112926222837853	[44]	[34,0,0]	0	hSpCas9	negative selection	1715247
197409984	197410007	2	+	26627737	HeLa	viability after 18 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	0.17606883013977326	[42]	[21,2,22]	1	hSpCas9	negative selection	1715248
197420498	197420521	2	-	26627737	HeLa	viability after 18 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.2286612839502995	[542]	[37,44,28]	-9	hSpCas9	negative selection	1715249
197421081	197421104	2	-	26627737	HeLa	viability after 18 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	0.548440576846669	[319]	[100,115,288]	4	hSpCas9	negative selection	1715250
197423909	197423932	2	-	26627737	HeLa	viability after 18 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.425580001045177	[217]	[4,119,44]	-4	hSpCas9	negative selection	1715251
197434971	197434994	2	-	26627737	HeLa	viability after 18 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.5117716904442147	[287]	[18,0,32]	-9	hSpCas9	negative selection	1715252
197408527	197408550	2	-	26627737	HCT116	viability after 6 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-0.43946770850474925	[314]	[2,54]	-3	hSpCas9	negative selection	1797562
197409984	197410007	2	+	26627737	HCT116	viability after 6 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-0.8830593807455676	[279]	[19,25]	-5	hSpCas9	negative selection	1797563
197420498	197420521	2	-	26627737	HCT116	viability after 6 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-0.6199931445542205	[311]	[9,43]	-4	hSpCas9	negative selection	1797564
197421081	197421104	2	-	26627737	HCT116	viability after 6 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.227684278254172	[743]	[125,7]	-6	hSpCas9	negative selection	1797565
197423909	197423932	2	-	26627737	HCT116	viability after 6 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.8219224747119486	[542]	[46,48]	-5	hSpCas9	negative selection	1797566
197434971	197434994	2	-	26627737	HCT116	viability after 6 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.381686689703218	[273]	[3,0]	-9	hSpCas9	negative selection	1797567
197408527	197408550	2	-	26627737	HCT116	viability after 8 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-0.9247275062812237	[163]	[45,66,29]	-8	hSpCas9	negative selection	1879877
197409984	197410007	2	+	26627737	HCT116	viability after 8 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-0.6184323309101358	[138]	[68,29,50]	-6	hSpCas9	negative selection	1879878
197420498	197420521	2	-	26627737	HCT116	viability after 8 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-1.1414292087348117	[251]	[103,57,27]	-8	hSpCas9	negative selection	1879879
197421081	197421104	2	-	26627737	HCT116	viability after 8 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.7887104461193029	[329]	[77,107,128]	-7	hSpCas9	negative selection	1879880
197423909	197423932	2	-	26627737	HCT116	viability after 8 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.40973768349314654	[162]	[79,50,71]	-5	hSpCas9	negative selection	1879881
197434971	197434994	2	-	26627737	HCT116	viability after 8 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.576620792128347	[122]	[4,19,8]	-9	hSpCas9	negative selection	1879882
197408527	197408550	2	-	26627737	HCT116	viability after 9 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-0.7238330917284993	[314]	[22,72]	-5	hSpCas9	negative selection	1962192
197409984	197410007	2	+	26627737	HCT116	viability after 9 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	0.4431540198198589	[279]	[228,0]	3	hSpCas9	negative selection	1962193
197420498	197420521	2	-	26627737	HCT116	viability after 9 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-3.773948837576701	[311]	[9,2]	-9	hSpCas9	negative selection	1962194
197421081	197421104	2	-	26627737	HCT116	viability after 9 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-2.604023836134389	[743]	[30,33]	-9	hSpCas9	negative selection	1962195
197423909	197423932	2	-	26627737	HCT116	viability after 9 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-1.057981743988789	[542]	[115,32]	-6	hSpCas9	negative selection	1962196
197434971	197434994	2	-	26627737	HCT116	viability after 9 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-3.643162230041348	[273]	[11,0]	-9	hSpCas9	negative selection	1962197
197408527	197408550	2	-	26627737	HCT116	viability after 12 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-1.8244564340208622	[163]	[11,61,0]	-9	hSpCas9	negative selection	2044507
197409984	197410007	2	+	26627737	HCT116	viability after 12 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-0.7687662531349537	[138]	[44,24,57]	-7	hSpCas9	negative selection	2044508
197420498	197420521	2	-	26627737	HCT116	viability after 12 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-3.366245572470868	[251]	[19,16,0]	-9	hSpCas9	negative selection	2044509
197421081	197421104	2	-	26627737	HCT116	viability after 12 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.7698735705564173	[329]	[73,119,113]	-7	hSpCas9	negative selection	2044510
197423909	197423932	2	-	26627737	HCT116	viability after 12 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.9658136505471289	[162]	[53,56,19]	-8	hSpCas9	negative selection	2044511
197434971	197434994	2	-	26627737	HCT116	viability after 12 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-6.0143494099084105	[122]	[0,0,0]	-9	hSpCas9	negative selection	2044512
197408527	197408550	2	-	26627737	HCT116	viability after 15 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-1.1960773581653628	[163]	[18,90,10]	-8	hSpCas9	negative selection	2126822
197409984	197410007	2	+	26627737	HCT116	viability after 15 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-0.8184518812020685	[138]	[45,53,35]	-7	hSpCas9	negative selection	2126823
197420498	197420521	2	-	26627737	HCT116	viability after 15 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.318528129833576	[251]	[29,14,41]	-9	hSpCas9	negative selection	2126824
197421081	197421104	2	-	26627737	HCT116	viability after 15 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.4680336543153615	[329]	[216,85,117]	-5	hSpCas9	negative selection	2126825
197423909	197423932	2	-	26627737	HCT116	viability after 15 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.9922623883431323	[162]	[67,51,23]	-7	hSpCas9	negative selection	2126826
197434971	197434994	2	-	26627737	HCT116	viability after 15 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.509607770596556	[122]	[0,0,6]	-9	hSpCas9	negative selection	2126827
197408527	197408550	2	-	26627737	HCT116	viability after 18 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-1.6004420121290213	[163]	[12,60,0]	-8	hSpCas9	negative selection	2209137
197409984	197410007	2	+	26627737	HCT116	viability after 18 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	0.5275578429650374	[138]	[143,56,91]	4	hSpCas9	negative selection	2209138
197420498	197420521	2	-	26627737	HCT116	viability after 18 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-3.456441213878434	[251]	[20,0,11]	-9	hSpCas9	negative selection	2209139
197421081	197421104	2	-	26627737	HCT116	viability after 18 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.5020705130982325	[329]	[172,95,67]	-4	hSpCas9	negative selection	2209140
197423909	197423932	2	-	26627737	HCT116	viability after 18 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.6649682189611599	[162]	[48,67,29]	-6	hSpCas9	negative selection	2209141
197434971	197434994	2	-	26627737	HCT116	viability after 18 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-5.893962129683818	[122]	[0,0,0]	-9	hSpCas9	negative selection	2209142
197428925	197428948	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACGCCACTGCACTCCAGCCCGG	SF3B1	ENSG00000115524	-0.23120917697478569	[21,115]	[6,17]	-1	dCas9-VP64	positive selection	2389371
197390642	197390665	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCGCCCAGGCTGGAGTGTAGCAG	SF3B1	ENSG00000115524	1.1996159195397276	[69,17]	[36,4]	5	dCas9-VP64	positive selection	2463362
197428925	197428948	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACGCCACTGCACTCCAGCCCGG	SF3B1	ENSG00000115524	-0.7543799798568478	[117,158]	[37,14]	-7	dCas9-VP64	positive selection	2484626
197390642	197390665	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCGCCCAGGCTGGAGTGTAGCAG	SF3B1	ENSG00000115524	2.7040346189546693	[41,50]	[11,181]	9	dCas9-VP64	positive selection	2558617
197423893	197423916	2	-	27260157	DLD1	viability	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-2.75937563724925	[]	[]	-9	hSpCas9	negative selection	2576483
197418864	197418887	2	+	27260157	DLD1	viability	GGGTTCCTGGGTTGCTAATCCGG	SF3B1	ENSG00000115524	-2.60675696972905	[]	[]	-9	hSpCas9	negative selection	2579245
197420497	197420520	2	-	27260157	DLD1	viability	ACCTCCAAAGATTGCAGACCGGG	SF3B1	ENSG00000115524	-1.62652184434066	[]	[]	-8	hSpCas9	negative selection	2583240
197409978	197410001	2	-	27260157	DLD1	viability	GGCATACTCCTTCCTTAAGATGG	SF3B1	ENSG00000115524	-2.22147691264114	[]	[]	-9	hSpCas9	negative selection	2583688
197405411	197405434	2	+	27260157	DLD1	viability	GTAGCTGTCAGCTTTCGAGCTGG	SF3B1	ENSG00000115524	-2.77537557432213	[]	[]	-9	hSpCas9	negative selection	2605127
197408515	197408538	2	-	27260157	DLD1	viability	GATCGAGGTGGAGATTCTATTGG	SF3B1	ENSG00000115524	-2.37116271908863	[]	[]	-9	hSpCas9	negative selection	2606357
197418883	197418906	2	-	27260157	DLD1	viability	GCACGAAAGTGTACGTATTCCGG	SF3B1	ENSG00000115524	1.07384291892841	[]	[]	9	hSpCas9	negative selection	2607212
197420493	197420516	2	+	27260157	DLD1	viability	TCTTCCCGGTCTGCAATCTTTGG	SF3B1	ENSG00000115524	-2.05942041344268	[]	[]	-8	hSpCas9	negative selection	2608547
197408440	197408463	2	+	27260157	DLD1	viability	CTTCCACCCATCTGACTAGCTGG	SF3B1	ENSG00000115524	0.939230492961137	[]	[]	9	hSpCas9	negative selection	2610001
197409850	197409873	2	+	27260157	DLD1	viability	CCTGGTGTATCACCTCGTCCAGG	SF3B1	ENSG00000115524	-2.08390876503224	[]	[]	-8	hSpCas9	negative selection	2610091
197408384	197408407	2	-	27260157	DLD1	viability	TGGCACACCAGCCATGAACATGG	SF3B1	ENSG00000115524	-3.44071888691083	[]	[]	-9	hSpCas9	negative selection	2611718
197408077	197408100	2	+	27260157	DLD1	viability	CGCCAAGCCTGAAGCTGTTCAGG	SF3B1	ENSG00000115524	1.04656656344016	[]	[]	9	hSpCas9	negative selection	2614345
197409883	197409906	2	-	27260157	DLD1	viability	ACACCTAGCCACACACCAGCGGG	SF3B1	ENSG00000115524	-3.24738892269	[]	[]	-9	hSpCas9	negative selection	2618843
197405423	197405446	2	+	27260157	DLD1	viability	TTTCGAGCTGGAGTTCGAATAGG	SF3B1	ENSG00000115524	-0.50776794770897	[]	[]	-4	hSpCas9	negative selection	2620709
197408497	197408520	2	-	27260157	DLD1	viability	ATTGGTGAAACACCGACTCCTGG	SF3B1	ENSG00000115524	-1.151783444457	[]	[]	-7	hSpCas9	negative selection	2621135
197418869	197418892	2	-	27260157	DLD1	viability	GTATTCCGGATTAGCAACCCAGG	SF3B1	ENSG00000115524	-0.320659411022097	[]	[]	-3	hSpCas9	negative selection	2623309
197408524	197408547	2	+	27260157	DLD1	viability	TCTCCACCTCGATCTGTTCGAGG	SF3B1	ENSG00000115524	-0.0566519543976159	[]	[]	0	hSpCas9	negative selection	2624295
197409850	197409873	2	-	27260157	DLD1	viability	CCTGGACGAGGTGATACACCAGG	SF3B1	ENSG00000115524	-0.248310590629988	[]	[]	-2	hSpCas9	negative selection	2641494
197408527	197408550	2	-	27260157	DLD1	viability	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-0.830384157889763	[]	[]	-6	hSpCas9	negative selection	2643618
197423908	197423931	2	-	27260157	DLD1	viability	CTTGATGAAGCTCAAGGAGTGGG	SF3B1	ENSG00000115524	-2.77173776844593	[]	[]	-9	hSpCas9	negative selection	2649674
197423893	197423916	2	-	27260157	HT1080	viability	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-2.67671329031921	[]	[]	-9	hSpCas9	negative selection	2652613
197418864	197418887	2	+	27260157	HT1080	viability	GGGTTCCTGGGTTGCTAATCCGG	SF3B1	ENSG00000115524	-1.72111822024314	[]	[]	-9	hSpCas9	negative selection	2655375
197420497	197420520	2	-	27260157	HT1080	viability	ACCTCCAAAGATTGCAGACCGGG	SF3B1	ENSG00000115524	-3.0784327250064	[]	[]	-9	hSpCas9	negative selection	2659370
197409978	197410001	2	-	27260157	HT1080	viability	GGCATACTCCTTCCTTAAGATGG	SF3B1	ENSG00000115524	-0.615260742104131	[]	[]	-8	hSpCas9	negative selection	2659818
197405411	197405434	2	+	27260157	HT1080	viability	GTAGCTGTCAGCTTTCGAGCTGG	SF3B1	ENSG00000115524	-2.55006382474025	[]	[]	-9	hSpCas9	negative selection	2681257
197408515	197408538	2	-	27260157	HT1080	viability	GATCGAGGTGGAGATTCTATTGG	SF3B1	ENSG00000115524	-2.2277812067966	[]	[]	-9	hSpCas9	negative selection	2682487
197418883	197418906	2	-	27260157	HT1080	viability	GCACGAAAGTGTACGTATTCCGG	SF3B1	ENSG00000115524	-0.0457875428343349	[]	[]	0	hSpCas9	negative selection	2683342
197420493	197420516	2	+	27260157	HT1080	viability	TCTTCCCGGTCTGCAATCTTTGG	SF3B1	ENSG00000115524	-2.97704594375923	[]	[]	-9	hSpCas9	negative selection	2684677
197408440	197408463	2	+	27260157	HT1080	viability	CTTCCACCCATCTGACTAGCTGG	SF3B1	ENSG00000115524	1.02422724804758	[]	[]	8	hSpCas9	negative selection	2686131
197409850	197409873	2	+	27260157	HT1080	viability	CCTGGTGTATCACCTCGTCCAGG	SF3B1	ENSG00000115524	-3.14730760738228	[]	[]	-9	hSpCas9	negative selection	2686221
197408384	197408407	2	-	27260157	HT1080	viability	TGGCACACCAGCCATGAACATGG	SF3B1	ENSG00000115524	-2.27651167121195	[]	[]	-9	hSpCas9	negative selection	2687848
197408077	197408100	2	+	27260157	HT1080	viability	CGCCAAGCCTGAAGCTGTTCAGG	SF3B1	ENSG00000115524	0.492359036385826	[]	[]	4	hSpCas9	negative selection	2690475
197409883	197409906	2	-	27260157	HT1080	viability	ACACCTAGCCACACACCAGCGGG	SF3B1	ENSG00000115524	-2.80762082072467	[]	[]	-9	hSpCas9	negative selection	2694973
197405423	197405446	2	+	27260157	HT1080	viability	TTTCGAGCTGGAGTTCGAATAGG	SF3B1	ENSG00000115524	-2.26084302975754	[]	[]	-9	hSpCas9	negative selection	2696839
197408497	197408520	2	-	27260157	HT1080	viability	ATTGGTGAAACACCGACTCCTGG	SF3B1	ENSG00000115524	-2.47835219646141	[]	[]	-9	hSpCas9	negative selection	2697265
197418869	197418892	2	-	27260157	HT1080	viability	GTATTCCGGATTAGCAACCCAGG	SF3B1	ENSG00000115524	-0.35605007421833	[]	[]	-7	hSpCas9	negative selection	2699439
197408524	197408547	2	+	27260157	HT1080	viability	TCTCCACCTCGATCTGTTCGAGG	SF3B1	ENSG00000115524	-1.12562652281109	[]	[]	-8	hSpCas9	negative selection	2700425
197409850	197409873	2	-	27260157	HT1080	viability	CCTGGACGAGGTGATACACCAGG	SF3B1	ENSG00000115524	-0.661237234268651	[]	[]	-8	hSpCas9	negative selection	2717624
197408527	197408550	2	-	27260157	HT1080	viability	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-2.17794754547019	[]	[]	-9	hSpCas9	negative selection	2719748
197423908	197423931	2	-	27260157	HT1080	viability	CTTGATGAAGCTCAAGGAGTGGG	SF3B1	ENSG00000115524	-2.72632215543109	[]	[]	-9	hSpCas9	negative selection	2725804
197423893	197423916	2	-	27260157	MKN45	viability	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-0.0304520213083428	[]	[]	0	hSpCas9	negative selection	2728743
197418864	197418887	2	+	27260157	MKN45	viability	GGGTTCCTGGGTTGCTAATCCGG	SF3B1	ENSG00000115524	-0.783092631734271	[]	[]	-7	hSpCas9	negative selection	2731505
197420497	197420520	2	-	27260157	MKN45	viability	ACCTCCAAAGATTGCAGACCGGG	SF3B1	ENSG00000115524	-1.44438263272554	[]	[]	-8	hSpCas9	negative selection	2735500
197409978	197410001	2	-	27260157	MKN45	viability	GGCATACTCCTTCCTTAAGATGG	SF3B1	ENSG00000115524	-0.0973048589596623	[]	[]	0	hSpCas9	negative selection	2735948
197405411	197405434	2	+	27260157	MKN45	viability	GTAGCTGTCAGCTTTCGAGCTGG	SF3B1	ENSG00000115524	-1.92383512751212	[]	[]	-9	hSpCas9	negative selection	2757387
197408515	197408538	2	-	27260157	MKN45	viability	GATCGAGGTGGAGATTCTATTGG	SF3B1	ENSG00000115524	-1.13519149551014	[]	[]	-8	hSpCas9	negative selection	2758617
197418883	197418906	2	-	27260157	MKN45	viability	GCACGAAAGTGTACGTATTCCGG	SF3B1	ENSG00000115524	0.121486383819563	[]	[]	4	hSpCas9	negative selection	2759472
197420493	197420516	2	+	27260157	MKN45	viability	TCTTCCCGGTCTGCAATCTTTGG	SF3B1	ENSG00000115524	-1.29462869072446	[]	[]	-8	hSpCas9	negative selection	2760807
197408440	197408463	2	+	27260157	MKN45	viability	CTTCCACCCATCTGACTAGCTGG	SF3B1	ENSG00000115524	1.57329176843817	[]	[]	9	hSpCas9	negative selection	2762261
197409850	197409873	2	+	27260157	MKN45	viability	CCTGGTGTATCACCTCGTCCAGG	SF3B1	ENSG00000115524	-1.90955250730823	[]	[]	-9	hSpCas9	negative selection	2762351
197408384	197408407	2	-	27260157	MKN45	viability	TGGCACACCAGCCATGAACATGG	SF3B1	ENSG00000115524	-1.87937724685175	[]	[]	-9	hSpCas9	negative selection	2763978
197408077	197408100	2	+	27260157	MKN45	viability	CGCCAAGCCTGAAGCTGTTCAGG	SF3B1	ENSG00000115524	1.58065147128841	[]	[]	9	hSpCas9	negative selection	2766605
197409883	197409906	2	-	27260157	MKN45	viability	ACACCTAGCCACACACCAGCGGG	SF3B1	ENSG00000115524	-2.40130855746962	[]	[]	-9	hSpCas9	negative selection	2771103
197405423	197405446	2	+	27260157	MKN45	viability	TTTCGAGCTGGAGTTCGAATAGG	SF3B1	ENSG00000115524	-0.086635266425463	[]	[]	0	hSpCas9	negative selection	2772969
197408497	197408520	2	-	27260157	MKN45	viability	ATTGGTGAAACACCGACTCCTGG	SF3B1	ENSG00000115524	-1.55529386183844	[]	[]	-9	hSpCas9	negative selection	2773395
197418869	197418892	2	-	27260157	MKN45	viability	GTATTCCGGATTAGCAACCCAGG	SF3B1	ENSG00000115524	-0.981633008535431	[]	[]	-7	hSpCas9	negative selection	2775569
197408524	197408547	2	+	27260157	MKN45	viability	TCTCCACCTCGATCTGTTCGAGG	SF3B1	ENSG00000115524	0.704814382995584	[]	[]	7	hSpCas9	negative selection	2776555
197409850	197409873	2	-	27260157	MKN45	viability	CCTGGACGAGGTGATACACCAGG	SF3B1	ENSG00000115524	-0.441444009788101	[]	[]	-6	hSpCas9	negative selection	2793754
197408527	197408550	2	-	27260157	MKN45	viability	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-0.158286766266299	[]	[]	0	hSpCas9	negative selection	2795878
197423908	197423931	2	-	27260157	MKN45	viability	CTTGATGAAGCTCAAGGAGTGGG	SF3B1	ENSG00000115524	-1.95234042966061	[]	[]	-9	hSpCas9	negative selection	2801934
197423893	197423916	2	-	27260157	RKO	viability	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-1.74454787400319	[]	[]	-9	hSpCas9	negative selection	2804873
197418864	197418887	2	+	27260157	RKO	viability	GGGTTCCTGGGTTGCTAATCCGG	SF3B1	ENSG00000115524	-1.16129153874262	[]	[]	-8	hSpCas9	negative selection	2807635
197420497	197420520	2	-	27260157	RKO	viability	ACCTCCAAAGATTGCAGACCGGG	SF3B1	ENSG00000115524	-2.15227656993225	[]	[]	-9	hSpCas9	negative selection	2811630
197409978	197410001	2	-	27260157	RKO	viability	GGCATACTCCTTCCTTAAGATGG	SF3B1	ENSG00000115524	-1.35130677304663	[]	[]	-8	hSpCas9	negative selection	2812078
197405411	197405434	2	+	27260157	RKO	viability	GTAGCTGTCAGCTTTCGAGCTGG	SF3B1	ENSG00000115524	-2.78095370045523	[]	[]	-9	hSpCas9	negative selection	2833517
197408515	197408538	2	-	27260157	RKO	viability	GATCGAGGTGGAGATTCTATTGG	SF3B1	ENSG00000115524	-1.39656501527624	[]	[]	-8	hSpCas9	negative selection	2834747
197418883	197418906	2	-	27260157	RKO	viability	GCACGAAAGTGTACGTATTCCGG	SF3B1	ENSG00000115524	-0.205132798655948	[]	[]	-1	hSpCas9	negative selection	2835602
197420493	197420516	2	+	27260157	RKO	viability	TCTTCCCGGTCTGCAATCTTTGG	SF3B1	ENSG00000115524	-2.39320025823749	[]	[]	-9	hSpCas9	negative selection	2836937
197408440	197408463	2	+	27260157	RKO	viability	CTTCCACCCATCTGACTAGCTGG	SF3B1	ENSG00000115524	0.556272170420489	[]	[]	3	hSpCas9	negative selection	2838391
197409850	197409873	2	+	27260157	RKO	viability	CCTGGTGTATCACCTCGTCCAGG	SF3B1	ENSG00000115524	-1.58425591593103	[]	[]	-9	hSpCas9	negative selection	2838481
197408384	197408407	2	-	27260157	RKO	viability	TGGCACACCAGCCATGAACATGG	SF3B1	ENSG00000115524	-2.49852201229302	[]	[]	-9	hSpCas9	negative selection	2840108
197408077	197408100	2	+	27260157	RKO	viability	CGCCAAGCCTGAAGCTGTTCAGG	SF3B1	ENSG00000115524	0.895718345095379	[]	[]	8	hSpCas9	negative selection	2842735
197409883	197409906	2	-	27260157	RKO	viability	ACACCTAGCCACACACCAGCGGG	SF3B1	ENSG00000115524	-2.38459672288974	[]	[]	-9	hSpCas9	negative selection	2847233
197405423	197405446	2	+	27260157	RKO	viability	TTTCGAGCTGGAGTTCGAATAGG	SF3B1	ENSG00000115524	-1.76374194209977	[]	[]	-9	hSpCas9	negative selection	2849099
197408497	197408520	2	-	27260157	RKO	viability	ATTGGTGAAACACCGACTCCTGG	SF3B1	ENSG00000115524	-1.49038956367182	[]	[]	-8	hSpCas9	negative selection	2849525
197418869	197418892	2	-	27260157	RKO	viability	GTATTCCGGATTAGCAACCCAGG	SF3B1	ENSG00000115524	-0.0653296092696191	[]	[]	0	hSpCas9	negative selection	2851699
197408524	197408547	2	+	27260157	RKO	viability	TCTCCACCTCGATCTGTTCGAGG	SF3B1	ENSG00000115524	-1.26430010848637	[]	[]	-8	hSpCas9	negative selection	2852685
197409850	197409873	2	-	27260157	RKO	viability	CCTGGACGAGGTGATACACCAGG	SF3B1	ENSG00000115524	-0.592275475154922	[]	[]	-7	hSpCas9	negative selection	2869884
197408527	197408550	2	-	27260157	RKO	viability	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-1.81206441017336	[]	[]	-9	hSpCas9	negative selection	2872008
197423908	197423931	2	-	27260157	RKO	viability	CTTGATGAAGCTCAAGGAGTGGG	SF3B1	ENSG00000115524	-1.75992932952591	[]	[]	-9	hSpCas9	negative selection	2878064
197423893	197423916	2	-	27260157	SF268	viability	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-1.40432357217943	[]	[]	-8	hSpCas9	negative selection	2881003
197418864	197418887	2	+	27260157	SF268	viability	GGGTTCCTGGGTTGCTAATCCGG	SF3B1	ENSG00000115524	-0.866080795839688	[]	[]	-6	hSpCas9	negative selection	2883765
197420497	197420520	2	-	27260157	SF268	viability	ACCTCCAAAGATTGCAGACCGGG	SF3B1	ENSG00000115524	-2.48032556094798	[]	[]	-9	hSpCas9	negative selection	2887760
197409978	197410001	2	-	27260157	SF268	viability	GGCATACTCCTTCCTTAAGATGG	SF3B1	ENSG00000115524	-0.558048090815791	[]	[]	-4	hSpCas9	negative selection	2888208
197405411	197405434	2	+	27260157	SF268	viability	GTAGCTGTCAGCTTTCGAGCTGG	SF3B1	ENSG00000115524	-2.90499108430439	[]	[]	-9	hSpCas9	negative selection	2909647
197408515	197408538	2	-	27260157	SF268	viability	GATCGAGGTGGAGATTCTATTGG	SF3B1	ENSG00000115524	-0.750684114792975	[]	[]	-6	hSpCas9	negative selection	2910877
197418883	197418906	2	-	27260157	SF268	viability	GCACGAAAGTGTACGTATTCCGG	SF3B1	ENSG00000115524	-0.177885594371857	[]	[]	-1	hSpCas9	negative selection	2911732
197420493	197420516	2	+	27260157	SF268	viability	TCTTCCCGGTCTGCAATCTTTGG	SF3B1	ENSG00000115524	-2.148946051327	[]	[]	-9	hSpCas9	negative selection	2913067
197408440	197408463	2	+	27260157	SF268	viability	CTTCCACCCATCTGACTAGCTGG	SF3B1	ENSG00000115524	0.86146706816413	[]	[]	9	hSpCas9	negative selection	2914521
197409850	197409873	2	+	27260157	SF268	viability	CCTGGTGTATCACCTCGTCCAGG	SF3B1	ENSG00000115524	-2.6669976490168	[]	[]	-9	hSpCas9	negative selection	2914611
197408384	197408407	2	-	27260157	SF268	viability	TGGCACACCAGCCATGAACATGG	SF3B1	ENSG00000115524	-2.11587757311199	[]	[]	-9	hSpCas9	negative selection	2916238
197408077	197408100	2	+	27260157	SF268	viability	CGCCAAGCCTGAAGCTGTTCAGG	SF3B1	ENSG00000115524	0.845420739706563	[]	[]	9	hSpCas9	negative selection	2918865
197409883	197409906	2	-	27260157	SF268	viability	ACACCTAGCCACACACCAGCGGG	SF3B1	ENSG00000115524	-1.66094335923463	[]	[]	-8	hSpCas9	negative selection	2923363
197405423	197405446	2	+	27260157	SF268	viability	TTTCGAGCTGGAGTTCGAATAGG	SF3B1	ENSG00000115524	-0.799267456903967	[]	[]	-6	hSpCas9	negative selection	2925229
197408497	197408520	2	-	27260157	SF268	viability	ATTGGTGAAACACCGACTCCTGG	SF3B1	ENSG00000115524	-2.23810714093083	[]	[]	-9	hSpCas9	negative selection	2925655
197418869	197418892	2	-	27260157	SF268	viability	GTATTCCGGATTAGCAACCCAGG	SF3B1	ENSG00000115524	-0.942606152103281	[]	[]	-6	hSpCas9	negative selection	2927829
197408524	197408547	2	+	27260157	SF268	viability	TCTCCACCTCGATCTGTTCGAGG	SF3B1	ENSG00000115524	-0.303150156445852	[]	[]	-2	hSpCas9	negative selection	2928815
197409850	197409873	2	-	27260157	SF268	viability	CCTGGACGAGGTGATACACCAGG	SF3B1	ENSG00000115524	-0.718273310070082	[]	[]	-5	hSpCas9	negative selection	2946014
197408527	197408550	2	-	27260157	SF268	viability	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-2.03237912209903	[]	[]	-8	hSpCas9	negative selection	2948138
197423908	197423931	2	-	27260157	SF268	viability	CTTGATGAAGCTCAAGGAGTGGG	SF3B1	ENSG00000115524	-2.79321576849307	[]	[]	-9	hSpCas9	negative selection	2954194
197434971	197434994	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-0.31905218566463767	[1,1]	[1,0]	-4	hSpCas9	positive selection	3019770
197423893	197423916	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-0.5388179777261372	[3,4]	[2,1]	-7	hSpCas9	positive selection	3019771
197423866	197423889	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	0.3910169416775463	[3,3]	[2,5]	7	hSpCas9	positive selection	3019772
197423909	197423932	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.76974012086017	[1,1]	[0,0]	-8	hSpCas9	positive selection	3019773
197434971	197434994	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-0.06378034039018043	[1,1]	[1,0]	-1	hSpCas9	positive selection	3087628
197423893	197423916	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-0.6348421593872805	[3,3]	[3,0]	-8	hSpCas9	positive selection	3087629
197423866	197423889	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-0.19990967975196045	[3,3]	[1,2]	-3	hSpCas9	positive selection	3087630
197423909	197423932	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.2996057082478464	[1,1]	[1,0]	-4	hSpCas9	positive selection	3087631
197434971	197434994		-	24336571	A375	resistance to PLX after 7 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	0.017404397617454492	[2,2]	[2,2]	0	hSpCas9	positive selection	3143703
197421096	197421119		-	24336571	A375	resistance to PLX after 7 days	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.05033522492760789	[18,19]	[15,20]	-1	hSpCas9	positive selection	3143704
197434971	197434994		-	24336571	A375	resistance to PLX after 14 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	0.5603992548194152	[3,1]	[1,1]	5	hSpCas9	positive selection	3201496
197421096	197421119		-	24336571	A375	resistance to PLX after 14 days	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.8728022485259032	[20,18]	[4,4]	-8	hSpCas9	positive selection	3201497
197434971	197434994		-	24336571	A375	viability after 7 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.0733916724320816	[13]	[2,2]	-9	hSpCas9	negative selection	3259289
197421096	197421119		-	24336571	A375	viability after 7 days	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.5837469454293964	[30]	[18,19]	-7	hSpCas9	negative selection	3259290
197434971	197434994		-	24336571	A375	viability after 14 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.0396115286085603	[13]	[3,1]	-9	hSpCas9	negative selection	3317082
197421096	197421119		-	24336571	A375	viability after 14 days	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.5236515206598106	[30]	[20,18]	-6	hSpCas9	negative selection	3317083
197421028	197421051	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	0.7495315712471388	[90,90]	[0,0]	3	hSpCas9	positive selection	3392038
197418554	197418577	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	1.0093986980022496	[75,75]	[0,0]	4	hSpCas9	positive selection	3392039
197421024	197421047	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	1.3265888738829488	[60,60]	[0,0]	6	hSpCas9	positive selection	3392040
197434971	197434994	2	-	26780180	HT29	viability (Avana library 4 designs)	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	6.14435878476313	[]	[]	9	hSpCas9	negative selection	3458270
197423893	197423916	2	-	26780180	HT29	viability (Avana library 4 designs)	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	1.83442402104225	[]	[]	7	hSpCas9	negative selection	3458271
197423866	197423889	2	-	26780180	HT29	viability (Avana library 4 designs)	TATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	5.23908215796827	[]	[]	9	hSpCas9	negative selection	3458272
197423909	197423932	2	-	26780180	HT29	viability (Avana library 4 designs)	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	3.71653029148094	[]	[]	9	hSpCas9	negative selection	3458273
197434971	197434994	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-19.4978240069525	[]	[]	-9	hSpCas9	negative selection	3557629
197423866	197423889	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-14.7297335971348	[]	[]	-9	hSpCas9	negative selection	3557630
197423909	197423932	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-9.12559936064396	[]	[]	-7	hSpCas9	negative selection	3557631
197423893	197423916	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	5.16248641456289	[]	[]	8	hSpCas9	negative selection	3557632
197423885	197423908	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATAATAACCTGTAGAATCGAGG	SF3B1	ENSG00000115524	-13.678644630083	[]	[]	-8	hSpCas9	negative selection	3557633
197423914	197423937	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-1.33802038577399	[]	[]	-2	hSpCas9	negative selection	3557634
197434971	197434994	2	-	26780180	A375	viability (Avana lentiGuide)	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	36.7331597532158	[]	[]	9	hSpCas9	negative selection	3666288
197423866	197423889	2	-	26780180	A375	viability (Avana lentiGuide)	TATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	12.9150046170867	[]	[]	7	hSpCas9	negative selection	3666289
197423909	197423932	2	-	26780180	A375	viability (Avana lentiGuide)	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	21.4162158287832	[]	[]	9	hSpCas9	negative selection	3666290
197423893	197423916	2	-	26780180	A375	viability (Avana lentiGuide)	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	5.61292565306874	[]	[]	5	hSpCas9	negative selection	3666291
197423885	197423908	2	+	26780180	A375	viability (Avana lentiGuide)	CATAATAACCTGTAGAATCGAGG	SF3B1	ENSG00000115524	15.7653344697774	[]	[]	8	hSpCas9	negative selection	3666292
197423914	197423937	2	-	26780180	A375	viability (Avana lentiGuide)	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	18.4176279384852	[]	[]	8	hSpCas9	negative selection	3666293
197434971	197434994	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.70403409065796	[5]	[1,0]	-9	hSpCas9	positive selection	3774895
197423866	197423889	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-1.2699752857433122	[6]	[2,1]	-9	hSpCas9	positive selection	3774896
197423909	197423932	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.3414197279781227	[4]	[3,2]	-5	hSpCas9	positive selection	3774897
197423893	197423916	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	0.32495730476379936	[4]	[5,6]	8	hSpCas9	positive selection	3774898
197423885	197423908	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATAATAACCTGTAGAATCGAGG	SF3B1	ENSG00000115524	-0.8248538488521322	[6]	[3,2]	-8	hSpCas9	positive selection	3774899
197423914	197423937	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-0.40119097281856997	[4]	[4,2]	-5	hSpCas9	positive selection	3774900
197434971	197434994	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.5106294291490108	[5]	[0,1]	-9	hSpCas9	positive selection	3883502
197423866	197423889	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-1.734668440652912	[6]	[1,0]	-9	hSpCas9	positive selection	3883503
197423909	197423932	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-2.1370543406772233	[4]	[0,0]	-9	hSpCas9	positive selection	3883504
197423893	197423916	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-0.03442076943454603	[6]	[4,5]	0	hSpCas9	positive selection	3883505
197423885	197423908	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATAATAACCTGTAGAATCGAGG	SF3B1	ENSG00000115524	-0.8223379945199835	[5]	[1,2]	-8	hSpCas9	positive selection	3883506
197423914	197423937	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-0.06348286185272431	[4]	[3,4]	-1	hSpCas9	positive selection	3883507
197434971	197434994	2	-	26780180	A375	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	2.40406055547303	[]	[]	9	hSpCas9	negative selection	3993539
197421024	197421047	2	+	26780180	A375	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	1.78692102108306	[]	[]	9	hSpCas9	negative selection	3993540
197434964	197434987	2	+	26780180	A375	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	1.91141463610599	[]	[]	9	hSpCas9	negative selection	3993541
197418554	197418577	2	-	26780180	A375	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	1.61124043124303	[]	[]	8	hSpCas9	negative selection	3993542
197421028	197421051	2	-	26780180	A375	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	1.84685339668178	[]	[]	9	hSpCas9	negative selection	3993543
197421096	197421119	2	-	26780180	A375	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	1.69243444111447	[]	[]	9	hSpCas9	negative selection	3993544
197434971	197434994	2	-	26780180	HT29	viability (GeCKOv2 library)	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	3.13039641056495	[]	[]	9	hSpCas9	negative selection	4101505
197421024	197421047	2	+	26780180	HT29	viability (GeCKOv2 library)	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	2.18164751820885	[]	[]	9	hSpCas9	negative selection	4101506
197434964	197434987	2	+	26780180	HT29	viability (GeCKOv2 library)	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	2.04769292199055	[]	[]	9	hSpCas9	negative selection	4101507
197418554	197418577	2	-	26780180	HT29	viability (GeCKOv2 library)	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	2.07032313816453	[]	[]	9	hSpCas9	negative selection	4101508
197421028	197421051	2	-	26780180	HT29	viability (GeCKOv2 library)	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	2.70760537094876	[]	[]	9	hSpCas9	negative selection	4101509
197421096	197421119	2	-	26780180	HT29	viability (GeCKOv2 library)	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	1.04257387687661	[]	[]	5	hSpCas9	negative selection	4101510
197434971	197434994	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-0.49932090857294964	[1]	[0,0]	-8	hSpCas9	positive selection	4169601
197421096	197421119	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.2860140411273829	[4]	[2,2]	-6	hSpCas9	positive selection	4169602
197434971	197434994	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	2.2143481380446426	[0]	[3,0,1,3]	9	hSpCas9	positive selection	4233623
197421096	197421119	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	0.6771964106765641	[5]	[3,4,0,3]	4	hSpCas9	positive selection	4233624
197434971	197434994	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.0648666465836212	[3]	[1,0]	-9	hSpCas9	positive selection	4297330
197421096	197421119	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.46627131047968273	[4]	[2,1]	-7	hSpCas9	positive selection	4297331
197434964	197434987	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.24645134465922042	[3]	[1,2]	-5	hSpCas9	positive selection	4297332
197421028	197421051	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.2926483422479667	[2]	[0,0]	-9	hSpCas9	positive selection	4361584
197418554	197418577	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.7382662069558419	[2]	[1,0]	-9	hSpCas9	positive selection	4361585
197421024	197421047	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-0.44956008495512645	[2]	[1,0]	-7	hSpCas9	positive selection	4361586
197421049	197421071	2	+	27760321	OCIAML3	viability	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	-4.567040931960058	[0,54]	[0,0]	-9	hSpCas9	negative selection	4438305
197421081	197421103	2	-	27760321	OCIAML3	viability	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.5001133268972578	[520,416]	[236,284]	-5	hSpCas9	negative selection	4438306
197423866	197423888	2	-	27760321	OCIAML3	viability	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-1.0522360824400852	[141,121]	[66,26]	-7	hSpCas9	negative selection	4438307
197423879	197423901	2	-	27760321	OCIAML3	viability	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	-3.5834442826317217	[50,33]	[0,4]	-9	hSpCas9	negative selection	4438308
197423893	197423915	2	-	27760321	OCIAML3	viability	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-1.160237612475496	[314,229]	[103,81]	-8	hSpCas9	negative selection	4438309
197421049	197421071	2	+	27760321	OCIAML2	viability	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	-4.615786297225107	[0,54]	[0,0]	-9	hSpCas9	negative selection	4521768
197421081	197421103	2	-	27760321	OCIAML2	viability	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.13344718577659187	[520,416]	[320,373]	-2	hSpCas9	negative selection	4521769
197423866	197423888	2	-	27760321	OCIAML2	viability	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-1.3304829437125991	[141,121]	[34,51]	-8	hSpCas9	negative selection	4521770
197423879	197423901	2	-	27760321	OCIAML2	viability	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	0.12418083649984002	[50,33]	[39,32]	1	hSpCas9	negative selection	4521771
197423893	197423915	2	-	27760321	OCIAML2	viability	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-0.3302366600897816	[314,229]	[158,192]	-4	hSpCas9	negative selection	4521772
197421049	197421071	2	+	27760321	MV411	viability	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	-4.321962363045376	[0,54]	[0,0]	-9	hSpCas9	negative selection	4605231
197421081	197421103	2	-	27760321	MV411	viability	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.8830918558713795	[520,416]	[205,107]	-5	hSpCas9	negative selection	4605232
197423866	197423888	2	-	27760321	MV411	viability	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-3.337196356451895	[141,121]	[0,19]	-9	hSpCas9	negative selection	4605233
197423879	197423901	2	-	27760321	MV411	viability	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	0.09585088198332103	[50,33]	[3,67]	0	hSpCas9	negative selection	4605234
197423893	197423915	2	-	27760321	MV411	viability	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-1.10905256834761	[314,229]	[48,132]	-6	hSpCas9	negative selection	4605235
197421049	197421071	2	+	27760321	HL60	viability	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	-4.030853445737057	[0,54]	[1,0]	-9	hSpCas9	negative selection	4688694
197421081	197421103	2	-	27760321	HL60	viability	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.04472771276926535	[520,416]	[410,324]	0	hSpCas9	negative selection	4688695
197423866	197423888	2	-	27760321	HL60	viability	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-1.2831634838361623	[141,121]	[49,37]	-8	hSpCas9	negative selection	4688696
197423879	197423901	2	-	27760321	HL60	viability	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	-1.524149602463119	[50,33]	[8,14]	-8	hSpCas9	negative selection	4688697
197423893	197423915	2	-	27760321	HL60	viability	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-1.0102977960977344	[314,229]	[107,110]	-7	hSpCas9	negative selection	4688698
197421049	197421071	2	+	27760321	HT1080	viability	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	-2.527142076994611	[54,42]	[0,5]	-7	hSpCas9	negative selection	4772157
197421081	197421103	2	-	27760321	HT1080	viability	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.5226115333829376	[416,325]	[50,159]	-2	hSpCas9	negative selection	4772158
197423866	197423888	2	-	27760321	HT1080	viability	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-5.433530874825494	[121,94]	[0,0]	-8	hSpCas9	negative selection	4772159
197423879	197423901	2	-	27760321	HT1080	viability	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	-3.604469782789593	[33,26]	[0,0]	-7	hSpCas9	negative selection	4772160
197423893	197423915	2	-	27760321	HT1080	viability	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-3.410252151357768	[229,179]	[0,14]	-7	hSpCas9	negative selection	4772161
197421049	197421071	2	+	27760321	HT29	viability after 7 days	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	0.19477213149431716	[54,42]	[12,96,96]	3	hSpCas9	negative selection	4855620
197421081	197421103	2	-	27760321	HT29	viability after 7 days	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.4057316341377267	[416,325]	[399,298,386]	-5	hSpCas9	negative selection	4855621
197423866	197423888	2	-	27760321	HT29	viability after 7 days	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-2.873144180718529	[121,94]	[3,1,47]	-9	hSpCas9	negative selection	4855622
197423879	197423901	2	-	27760321	HT29	viability after 7 days	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	-3.845142817677215	[33,26]	[0,5,0]	-9	hSpCas9	negative selection	4855623
197423893	197423915	2	-	27760321	HT29	viability after 7 days	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-0.9784741220403266	[229,179]	[67,132,188]	-8	hSpCas9	negative selection	4855624
197421049	197421071	2	+	27760321	HT29	viability after 25 days	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	-0.8211528453702104	[54,42]	[76,10,0]	-6	hSpCas9	negative selection	4939083
197421081	197421103	2	-	27760321	HT29	viability after 25 days	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.77100513017558	[416,325]	[81,140,155]	-8	hSpCas9	negative selection	4939084
197423866	197423888	2	-	27760321	HT29	viability after 25 days	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-6.953213139672018	[121,94]	[0,0,0]	-9	hSpCas9	negative selection	4939085
197423879	197423901	2	-	27760321	HT29	viability after 25 days	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	-2.099203870474317	[33,26]	[2,19,0]	-8	hSpCas9	negative selection	4939086
197423893	197423915	2	-	27760321	HT29	viability after 25 days	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-2.399776096595832	[229,179]	[33,44,55]	-8	hSpCas9	negative selection	4939087
197421049	197421071	2	+	27760321	HT29	viability after 22 days	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	-1.4330177441747631	[54,42]	[13,41,6]	-7	hSpCas9	negative selection	5022546
197421081	197421103	2	-	27760321	HT29	viability after 22 days	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-2.587916399329782	[416,325]	[62,136,13]	-8	hSpCas9	negative selection	5022547
197423866	197423888	2	-	27760321	HT29	viability after 22 days	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-3.0762256341563123	[121,94]	[34,0,7]	-8	hSpCas9	negative selection	5022548
197423879	197423901	2	-	27760321	HT29	viability after 22 days	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	-2.070557989221964	[33,26]	[15,0,7]	-8	hSpCas9	negative selection	5022549
197423893	197423915	2	-	27760321	HT29	viability after 22 days	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-1.0689181676572492	[229,179]	[231,67,34]	-7	hSpCas9	negative selection	5022550
197421049	197421071	2	+	27760321	HT29	viability after 19 days	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	-0.9365639302508981	[54,42]	[43,32,12]	-6	hSpCas9	negative selection	5106009
197421081	197421103	2	-	27760321	HT29	viability after 19 days	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-2.585271568136688	[416,325]	[100,109,6]	-8	hSpCas9	negative selection	5106010
197423866	197423888	2	-	27760321	HT29	viability after 19 days	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-3.6927144275102197	[121,94]	[27,0,1]	-9	hSpCas9	negative selection	5106011
197423879	197423901	2	-	27760321	HT29	viability after 19 days	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	-5.125630627072163	[33,26]	[0,0,0]	-9	hSpCas9	negative selection	5106012
197423893	197423915	2	-	27760321	HT29	viability after 19 days	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-1.7112587514524848	[229,179]	[27,50,128]	-7	hSpCas9	negative selection	5106013
197421049	197421071	2	+	27760321	HT29	viability after 16 days	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	-1.6806361686285136	[54,42]	[34,16,0]	-8	hSpCas9	negative selection	5189472
197421081	197421103	2	-	27760321	HT29	viability after 16 days	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.7213189150508932	[416,325]	[127,62,188]	-8	hSpCas9	negative selection	5189473
197423866	197423888	2	-	27760321	HT29	viability after 16 days	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-2.8979133253933513	[121,94]	[4,7,34]	-9	hSpCas9	negative selection	5189474
197423879	197423901	2	-	27760321	HT29	viability after 16 days	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	-3.433250240675698	[33,26]	[7,0,0]	-9	hSpCas9	negative selection	5189475
197423893	197423915	2	-	27760321	HT29	viability after 16 days	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-1.4812035072802814	[229,179]	[70,136,35]	-8	hSpCas9	negative selection	5189476
197421049	197421071	2	+	27760321	HT29	viability after 13 days	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	0.1205510968017518	[54,42]	[66,100,19]	1	hSpCas9	negative selection	5272935
197421081	197421103	2	-	27760321	HT29	viability after 13 days	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.3890702947701283	[416,325]	[119,246,128]	-8	hSpCas9	negative selection	5272936
197423866	197423888	2	-	27760321	HT29	viability after 13 days	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-1.9807672863266323	[121,94]	[65,4,24]	-8	hSpCas9	negative selection	5272937
197423879	197423901	2	-	27760321	HT29	viability after 13 days	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	-1.7449072637370913	[33,26]	[4,20,5]	-8	hSpCas9	negative selection	5272938
197423893	197423915	2	-	27760321	HT29	viability after 13 days	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-1.7161349601738698	[229,179]	[77,63,74]	-8	hSpCas9	negative selection	5272939
197421049	197421071	2	+	27760321	HT29	viability after 10 days	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	-0.43901207687075283	[54,42]	[47,35,50]	-5	hSpCas9	negative selection	5356398
197421081	197421103	2	-	27760321	HT29	viability after 10 days	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-0.49534030098795884	[416,325]	[229,469,291]	-6	hSpCas9	negative selection	5356399
197423866	197423888	2	-	27760321	HT29	viability after 10 days	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-3.2104274330871023	[121,94]	[4,20,17]	-9	hSpCas9	negative selection	5356400
197423879	197423901	2	-	27760321	HT29	viability after 10 days	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	-3.1666520759062715	[33,26]	[0,10,0]	-9	hSpCas9	negative selection	5356401
197423893	197423915	2	-	27760321	HT29	viability after 10 days	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-1.1515954751648145	[229,179]	[109,83,149]	-8	hSpCas9	negative selection	5356402
197421049	197421071	2	+	27760321	MOLM13	viability	TATCATTAAGCAATGCCACAGG	SF3B1	ENSG00000115524	-4.095905550217781	[0,54]	[0,0]	-9	hSpCas9	negative selection	5439861
197421081	197421103	2	-	27760321	MOLM13	viability	TGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	0.1764801245742894	[520,416]	[299,294]	1	hSpCas9	negative selection	5439862
197423866	197423888	2	-	27760321	MOLM13	viability	ATGACCAGGAAATTTATGGTGG	SF3B1	ENSG00000115524	-2.0650796151791675	[141,121]	[0,31]	-8	hSpCas9	negative selection	5439863
197423879	197423901	2	-	27760321	MOLM13	viability	TCTACAGGTTATTATGACCAGG	SF3B1	ENSG00000115524	1.1445773581182883	[50,33]	[0,95]	7	hSpCas9	negative selection	5439864
197423893	197423915	2	-	27760321	MOLM13	viability	GAGTGGGCCTCGATTCTACAGG	SF3B1	ENSG00000115524	-0.5181560654013849	[314,229]	[0,195]	-3	hSpCas9	negative selection	5439865
197434545	197434568	2	+	27661255	K562	viability	GATTCAGTCTGCCGGAAAAGCGG	SF3B1	ENSG00000115524	0.021473938420798033	[1804,1774]	[1610,1315]	0	dCas9-KRAB	negative selection	5510485
197435035	197435058	2	-	27661255	K562	viability	GGCGACGAGCGGAAGTTCTTGGG	SF3B1	ENSG00000115524	-1.0019317878599294	[684,547]	[261,233]	-8	dCas9-KRAB	negative selection	5510486
197434971	197434994	2	-	27260156	BXPC3	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.9213453134002167	[571]	[161,189,111,163]	-9	hSpCas9	negative selection	5569790
197421096	197421119	2	-	27260156	BXPC3	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.4674095796156976	[988]	[715,611,892,783]	-7	hSpCas9	negative selection	5569791
197434964	197434987	2	+	27260156	BXPC3	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.7850578104088454	[724]	[349,442,459,523]	-9	hSpCas9	negative selection	5569792
197421028	197421051	2	-	27260156	BXPC3	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.359779861764923	[452]	[186,178,177,193]	-9	hSpCas9	negative selection	5634044
197418554	197418577	2	-	27260156	BXPC3	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.4695856260364936	[362]	[276,228,313,277]	-8	hSpCas9	negative selection	5634045
197421024	197421047	2	+	27260156	BXPC3	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.3261810400596974	[318]	[106,168,127,126]	-9	hSpCas9	negative selection	5634046
197434971	197434994	2	-	27260156	A673	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.2234153551580456	[571]	[332,352,210,281]	-9	hSpCas9	negative selection	5691041
197421096	197421119	2	-	27260156	A673	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.36368007743565334	[988]	[907,838,1010,931]	-7	hSpCas9	negative selection	5691042
197434964	197434987	2	+	27260156	A673	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.6035772830138442	[724]	[559,516,637,574]	-9	hSpCas9	negative selection	5691043
197421028	197421051	2	-	27260156	A673	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.7498924057102391	[452]	[280,335,371,296]	-9	hSpCas9	negative selection	5755295
197418554	197418577	2	-	27260156	A673	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.5857557380275107	[362]	[363,244,328,228]	-8	hSpCas9	negative selection	5755296
197421024	197421047	2	+	27260156	A673	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-0.7743004382266881	[318]	[218,207,214,254]	-9	hSpCas9	negative selection	5755297
197434971	197434994	2	-	27260156	A375	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-3.1888881302667187	[571]	[64,68,129,32]	-9	hSpCas9	negative selection	5812292
197421096	197421119	2	-	27260156	A375	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-1.0450696561319486	[988]	[505,579,570,579]	-8	hSpCas9	negative selection	5812293
197434964	197434987	2	+	27260156	A375	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.1528617761877926	[724]	[351,636,369,217]	-8	hSpCas9	negative selection	5812294
197421028	197421051	2	-	27260156	A375	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.302952722061912	[452]	[135,205,333,182]	-9	hSpCas9	negative selection	5876546
197418554	197418577	2	-	27260156	A375	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.9627132062297576	[362]	[153,373,157,205]	-8	hSpCas9	negative selection	5876547
197421024	197421047	2	+	27260156	A375	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.619577369078089	[318]	[36,135,191,120]	-9	hSpCas9	negative selection	5876548
197434971	197434994	2	-	27260156	COLO741	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.654273741012128	[571]	[287,226,188]	-9	hSpCas9	negative selection	5933543
197421096	197421119	2	-	27260156	COLO741	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.3578866889999627	[988]	[1092,958,917]	-6	hSpCas9	negative selection	5933544
197434964	197434987	2	+	27260156	COLO741	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.5398177608981545	[724]	[663,661,589]	-8	hSpCas9	negative selection	5933545
197421028	197421051	2	-	27260156	COLO741	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.1815611487704998	[452]	[317,152,295]	-9	hSpCas9	negative selection	5997797
197418554	197418577	2	-	27260156	COLO741	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.6665256197389122	[362]	[241,367,263]	-8	hSpCas9	negative selection	5997798
197421024	197421047	2	+	27260156	COLO741	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-0.46113348481410765	[318]	[331,240,315]	-7	hSpCas9	negative selection	5997799
197434971	197434994	2	-	27260156	CAL120	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-3.5683199910521424	[571]	[58,69,50]	-9	hSpCas9	negative selection	6054794
197421096	197421119	2	-	27260156	CAL120	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.9360439760400149	[988]	[563,847,507]	-8	hSpCas9	negative selection	6054795
197434964	197434987	2	+	27260156	CAL120	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.252572037262929	[724]	[258,324,530]	-9	hSpCas9	negative selection	6054796
197421028	197421051	2	-	27260156	CAL120	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.9138546943758286	[452]	[377,325,206]	-8	hSpCas9	negative selection	6119048
197418554	197418577	2	-	27260156	CAL120	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.0242905632510955	[362]	[473,171,60]	-8	hSpCas9	negative selection	6119049
197421024	197421047	2	+	27260156	CAL120	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.3568705128904592	[318]	[226,220,29]	-9	hSpCas9	negative selection	6119050
197434971	197434994	2	-	27260156	CADOES1	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.9092939186295963	[571]	[141,141,153,127]	-9	hSpCas9	negative selection	6176045
197421096	197421119	2	-	27260156	CADOES1	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.6245505814630073	[988]	[602,451,635,698]	-8	hSpCas9	negative selection	6176046
197434964	197434987	2	+	27260156	CADOES1	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.8080012493062859	[724]	[369,379,419,369]	-8	hSpCas9	negative selection	6176047
197421028	197421051	2	-	27260156	CADOES1	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.6091023910282495	[452]	[411,195,254,239]	-8	hSpCas9	negative selection	6240299
197418554	197418577	2	-	27260156	CADOES1	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.608771888614634	[362]	[242,152,225,264]	-8	hSpCas9	negative selection	6240300
197421024	197421047	2	+	27260156	CADOES1	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.2749496833277325	[318]	[119,121,110,137]	-9	hSpCas9	negative selection	6240301
197434971	197434994	2	-	27260156	EWS502	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-3.5797273456113947	[571]	[26,42,87,47]	-9	hSpCas9	negative selection	6297296
197421096	197421119	2	-	27260156	EWS502	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.48195775876024916	[988]	[721,917,564,788]	-7	hSpCas9	negative selection	6297297
197434964	197434987	2	+	27260156	EWS502	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.3758288633317053	[724]	[257,227,238,476]	-9	hSpCas9	negative selection	6297298
197421028	197421051	2	-	27260156	EWS502	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.7104888255804322	[452]	[112,149,152,175]	-9	hSpCas9	negative selection	6361550
197418554	197418577	2	-	27260156	EWS502	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.1411822447914675	[362]	[157,224,138,173]	-9	hSpCas9	negative selection	6361551
197421024	197421047	2	+	27260156	EWS502	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.4912410946314463	[318]	[140,85,120,131]	-9	hSpCas9	negative selection	6361552
197434971	197434994	2	-	27260156	EW8	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.5842103530957719	[571]	[145,36,208,214]	-9	hSpCas9	negative selection	6418547
197421096	197421119	2	-	27260156	EW8	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.49536031220344445	[988]	[564,548,532,630]	-7	hSpCas9	negative selection	6418548
197434964	197434987	2	+	27260156	EW8	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.7369536212301568	[724]	[430,388,275,334]	-8	hSpCas9	negative selection	6418549
197421028	197421051	2	-	27260156	EW8	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.1838106721219723	[452]	[167,171,93,223]	-9	hSpCas9	negative selection	6482801
197418554	197418577	2	-	27260156	EW8	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.613743825192387	[362]	[142,225,210,179]	-8	hSpCas9	negative selection	6482802
197421024	197421047	2	+	27260156	EW8	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.1172382482833485	[318]	[171,118,108,83]	-9	hSpCas9	negative selection	6482803
197434971	197434994	2	-	27260156	CORL105	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.6923309675810687	[571]	[214,188,223,203]	-9	hSpCas9	negative selection	6539798
197421096	197421119	2	-	27260156	CORL105	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.5448834258350196	[988]	[919,527,748,978]	-7	hSpCas9	negative selection	6539799
197434964	197434987	2	+	27260156	CORL105	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.4835072925938385	[724]	[542,495,767,645]	-7	hSpCas9	negative selection	6539800
197421028	197421051	2	-	27260156	CORL105	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.8111758734322243	[452]	[257,357,312,278]	-8	hSpCas9	negative selection	6604052
197418554	197418577	2	-	27260156	CORL105	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.0179606121362066	[362]	[142,166,225,303]	-9	hSpCas9	negative selection	6604053
197421024	197421047	2	+	27260156	CORL105	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.0500615614384663	[318]	[271,212,77,144]	-9	hSpCas9	negative selection	6604054
197434971	197434994	2	-	27260156	HS294T	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.3245349796943744	[571]	[14,32,75,57]	-9	hSpCas9	negative selection	6661049
197421096	197421119	2	-	27260156	HS294T	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.7754343128521501	[988]	[171,207,271,250]	-8	hSpCas9	negative selection	6661050
197434964	197434987	2	+	27260156	HS294T	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.8218066601171682	[724]	[101,121,205,220]	-8	hSpCas9	negative selection	6661051
197421028	197421051	2	-	27260156	HS294T	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.109371292331835	[452]	[61,84,83,97]	-9	hSpCas9	negative selection	6725303
197418554	197418577	2	-	27260156	HS294T	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.7655098897638952	[362]	[43,134,69,82]	-8	hSpCas9	negative selection	6725304
197421024	197421047	2	+	27260156	HS294T	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-0.914227629676955	[318]	[100,17,38,108]	-8	hSpCas9	negative selection	6725305
197434971	197434994	2	-	27260156	HCC44	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.6882416993020533	[571]	[28,90,64,200]	-9	hSpCas9	negative selection	6782300
197421096	197421119	2	-	27260156	HCC44	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.9830325061213514	[988]	[522,504,428,775]	-8	hSpCas9	negative selection	6782301
197434964	197434987	2	+	27260156	HCC44	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.4007401739635568	[724]	[308,245,378,325]	-9	hSpCas9	negative selection	6782302
197421028	197421051	2	-	27260156	HCC44	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.0897504900859591	[452]	[205,313,335,111]	-8	hSpCas9	negative selection	6846554
197418554	197418577	2	-	27260156	HCC44	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.6826357586685483	[362]	[47,149,84,206]	-9	hSpCas9	negative selection	6846555
197421024	197421047	2	+	27260156	HCC44	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.6856004292890483	[318]	[36,168,133,96]	-9	hSpCas9	negative selection	6846556
197434971	197434994	2	-	27260156	G402	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.7367479642448223	[571]	[158,315,134,224]	-9	hSpCas9	negative selection	6903551
197421096	197421119	2	-	27260156	G402	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.7438789659941836	[988]	[536,529,523,1225]	-7	hSpCas9	negative selection	6903552
197434964	197434987	2	+	27260156	G402	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.524916996023081	[724]	[237,397,328,260]	-9	hSpCas9	negative selection	6903553
197421028	197421051	2	-	27260156	G402	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.535211616719285	[452]	[182,109,159,297]	-9	hSpCas9	negative selection	6967805
197418554	197418577	2	-	27260156	G402	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.3005632302823174	[362]	[193,127,202,191]	-9	hSpCas9	negative selection	6967806
197421024	197421047	2	+	27260156	G402	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.2321122143940566	[318]	[114,374,74,104]	-8	hSpCas9	negative selection	6967807
197434971	197434994	2	-	27260156	L33	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.6818601873791856	[571]	[194,66,111,175]	-9	hSpCas9	negative selection	7024802
197421096	197421119	2	-	27260156	L33	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.09008560043578462	[988]	[870,339,633,1007]	-2	hSpCas9	negative selection	7024803
197434964	197434987	2	+	27260156	L33	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.11541469345201227	[724]	[672,301,379,661]	-3	hSpCas9	negative selection	7024804
197421028	197421051	2	-	27260156	L33	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.6979571262235673	[452]	[298,105,157,306]	-9	hSpCas9	negative selection	7089056
197418554	197418577	2	-	27260156	L33	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.39960760615446295	[362]	[257,111,155,320]	-7	hSpCas9	negative selection	7089057
197421024	197421047	2	+	27260156	L33	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.3317403179337597	[318]	[106,62,71,131]	-9	hSpCas9	negative selection	7089058
197434971	197434994	2	-	27260156	K562	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.9690114860247752	[571]	[12,45,68,349]	-9	hSpCas9	negative selection	7146053
197421096	197421119	2	-	27260156	K562	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-1.0194990314703822	[988]	[522,591,285,353]	-8	hSpCas9	negative selection	7146054
197434964	197434987	2	+	27260156	K562	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.4070698459948474	[724]	[144,152,352,298]	-9	hSpCas9	negative selection	7146055
197421028	197421051	2	-	27260156	K562	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.5069336195756664	[452]	[240,112,58,156]	-9	hSpCas9	negative selection	7210307
197418554	197418577	2	-	27260156	K562	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.7382089936376133	[362]	[97,108,458,103]	-7	hSpCas9	negative selection	7210308
197421024	197421047	2	+	27260156	K562	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.3297944009439835	[318]	[197,104,25,125]	-8	hSpCas9	negative selection	7210309
197434971	197434994	2	-	27260156	HT29	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-3.639104456943563	[571]	[113,15,65,30]	-9	hSpCas9	negative selection	7267304
197421096	197421119	2	-	27260156	HT29	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.9508543053268222	[988]	[564,874,549,522]	-8	hSpCas9	negative selection	7267305
197434964	197434987	2	+	27260156	HT29	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.138322681893174	[724]	[402,372,505,323]	-9	hSpCas9	negative selection	7267306
197421028	197421051	2	-	27260156	HT29	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.6419471382440929	[452]	[56,197,299,145]	-9	hSpCas9	negative selection	7331558
197418554	197418577	2	-	27260156	HT29	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.3139270811861248	[362]	[142,145,251,163]	-9	hSpCas9	negative selection	7331559
197421024	197421047	2	+	27260156	HT29	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.5470628160091473	[318]	[66,244,76,143]	-9	hSpCas9	negative selection	7331560
197434971	197434994	2	-	27260156	MHHES1	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.0217229044695388	[571]	[427,348,286,233]	-9	hSpCas9	negative selection	7388555
197421096	197421119	2	-	27260156	MHHES1	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.2679123515494709	[988]	[1030,905,902,863]	-5	hSpCas9	negative selection	7388556
197434964	197434987	2	+	27260156	MHHES1	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.7326959514066591	[724]	[340,592,493,512]	-8	hSpCas9	negative selection	7388557
197421028	197421051	2	-	27260156	MHHES1	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.47950665543513593	[452]	[677,393,188,258]	-7	hSpCas9	negative selection	7452809
197418554	197418577	2	-	27260156	MHHES1	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.9738860091028043	[362]	[288,184,178,186]	-9	hSpCas9	negative selection	7452810
197421024	197421047	2	+	27260156	MHHES1	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-0.5175636843061554	[318]	[400,234,198,192]	-7	hSpCas9	negative selection	7452811
197434971	197434994	2	-	27260156	MEWO	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.3264702461805589	[571]	[171,230,228]	-9	hSpCas9	negative selection	7509806
197421096	197421119	2	-	27260156	MEWO	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.4273254523332707	[988]	[745,743,584]	-7	hSpCas9	negative selection	7509807
197434964	197434987	2	+	27260156	MEWO	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.572128101126949	[724]	[487,402,483]	-8	hSpCas9	negative selection	7509808
197421028	197421051	2	-	27260156	MEWO	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.9749307035987466	[452]	[235,165,248]	-9	hSpCas9	negative selection	7574060
197418554	197418577	2	-	27260156	MEWO	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.5633145884220063	[362]	[366,231,116]	-8	hSpCas9	negative selection	7574061
197421024	197421047	2	+	27260156	MEWO	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-0.6928389252589114	[318]	[118,210,210]	-8	hSpCas9	negative selection	7574062
197434971	197434994	2	-	27260156	LNCAPCLONEFGC	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.9533512825762203	[571]	[74,58,80,54]	-9	hSpCas9	negative selection	7631057
197421096	197421119	2	-	27260156	LNCAPCLONEFGC	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.5762251245653098	[988]	[658,554,640,555]	-7	hSpCas9	negative selection	7631058
197434964	197434987	2	+	27260156	LNCAPCLONEFGC	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.1689220024619646	[724]	[342,271,281,269]	-9	hSpCas9	negative selection	7631059
197421028	197421051	2	-	27260156	LNCAPCLONEFGC	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.7458667573070088	[452]	[192,189,269,333]	-8	hSpCas9	negative selection	7695311
197418554	197418577	2	-	27260156	LNCAPCLONEFGC	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.2635677639448104	[362]	[178,78,178,119]	-9	hSpCas9	negative selection	7695312
197421024	197421047	2	+	27260156	LNCAPCLONEFGC	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.4284767446155917	[318]	[139,49,177,74]	-9	hSpCas9	negative selection	7695313
197434971	197434994	2	-	27260156	PANC0327	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.440512084816261	[571]	[29,16,38,8]	-9	hSpCas9	negative selection	7752308
197421096	197421119	2	-	27260156	PANC0327	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.404744397782821	[988]	[614,634,689,713]	-5	hSpCas9	negative selection	7752309
197434964	197434987	2	+	27260156	PANC0327	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.2702453288113755	[724]	[231,213,329,295]	-9	hSpCas9	negative selection	7752310
197421028	197421051	2	-	27260156	PANC0327	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.2612349268692027	[452]	[67,200,185,203]	-9	hSpCas9	negative selection	7816562
197418554	197418577	2	-	27260156	PANC0327	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.1502079875392353	[362]	[160,62,162,205]	-9	hSpCas9	negative selection	7816563
197421024	197421047	2	+	27260156	PANC0327	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.6415794775542856	[318]	[62,97,73,124]	-9	hSpCas9	negative selection	7816564
197434971	197434994	2	-	27260156	NCIH2009	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.2545623918681326	[571]	[119,98,274]	-9	hSpCas9	negative selection	7873559
197421096	197421119	2	-	27260156	NCIH2009	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.8061478089005787	[988]	[863,734,785]	-7	hSpCas9	negative selection	7873560
197434964	197434987	2	+	27260156	NCIH2009	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.8908072154966242	[724]	[577,612,451]	-8	hSpCas9	negative selection	7873561
197421028	197421051	2	-	27260156	NCIH2009	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.583972444941291	[452]	[220,262,149]	-9	hSpCas9	negative selection	7937813
197418554	197418577	2	-	27260156	NCIH2009	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.4054016114844489	[362]	[587,253,348]	-5	hSpCas9	negative selection	7937814
197421024	197421047	2	+	27260156	NCIH2009	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.9284545431202051	[318]	[99,154,91]	-9	hSpCas9	negative selection	7937815
197434971	197434994	2	-	27260156	NCIH1373	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.6289145562652156	[571]	[262,144,260,44]	-9	hSpCas9	negative selection	7994810
197421096	197421119	2	-	27260156	NCIH1373	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.7280323604516443	[988]	[955,460,671,170]	-6	hSpCas9	negative selection	7994811
197434964	197434987	2	+	27260156	NCIH1373	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.6266290173162944	[724]	[711,427,232,207]	-6	hSpCas9	negative selection	7994812
197421028	197421051	2	-	27260156	NCIH1373	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.7966691947763351	[452]	[558,309,74,69]	-7	hSpCas9	negative selection	8059064
197418554	197418577	2	-	27260156	NCIH1373	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.5739119107146746	[362]	[276,47,73,47]	-9	hSpCas9	negative selection	8059065
197421024	197421047	2	+	27260156	NCIH1373	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.5586987450052274	[318]	[89,41,116,64]	-9	hSpCas9	negative selection	8059066
197434971	197434994	2	-	27260156	PATU8902	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-5.570911487783746	[571]	[4,46,8,6]	-9	hSpCas9	negative selection	8116061
197421096	197421119	2	-	27260156	PATU8902	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-1.4926931375825512	[988]	[750,357,431,414]	-8	hSpCas9	negative selection	8116062
197434964	197434987	2	+	27260156	PATU8902	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.1780476976102197	[724]	[251,659,285,652]	-8	hSpCas9	negative selection	8116063
197421028	197421051	2	-	27260156	PATU8902	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.8456272882547485	[452]	[197,396,508,245]	-7	hSpCas9	negative selection	8180315
197418554	197418577	2	-	27260156	PATU8902	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.3590761617543132	[362]	[307,168,14,359]	-8	hSpCas9	negative selection	8180316
197421024	197421047	2	+	27260156	PATU8902	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-2.574909633932934	[318]	[85,76,91,32]	-9	hSpCas9	negative selection	8180317
197434971	197434994	2	-	27260156	PANC1	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.831975024585066	[571]	[54,86,68,67]	-9	hSpCas9	negative selection	8237312
197421096	197421119	2	-	27260156	PANC1	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.9139346374747203	[988]	[508,450,343,483]	-8	hSpCas9	negative selection	8237313
197434964	197434987	2	+	27260156	PANC1	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.7641913826342583	[724]	[306,408,370,380]	-8	hSpCas9	negative selection	8237314
197421028	197421051	2	-	27260156	PANC1	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.5294551104720737	[452]	[124,193,141,94]	-9	hSpCas9	negative selection	8301566
197418554	197418577	2	-	27260156	PANC1	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.398345602396526	[362]	[83,168,115,113]	-9	hSpCas9	negative selection	8301567
197421024	197421047	2	+	27260156	PANC1	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.0822767056393912	[318]	[115,207,127,86]	-8	hSpCas9	negative selection	8301568
197434971	197434994	2	-	27260156	PANC0813	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.6839386341210987	[571]	[154,286,266,126]	-9	hSpCas9	negative selection	8358563
197421096	197421119	2	-	27260156	PANC0813	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.5070986654506194	[988]	[706,948,871,734]	-6	hSpCas9	negative selection	8358564
197434964	197434987	2	+	27260156	PANC0813	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.5511415858148249	[724]	[483,778,551,503]	-7	hSpCas9	negative selection	8358565
197421028	197421051	2	-	27260156	PANC0813	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.224530954979179	[452]	[168,337,243,157]	-9	hSpCas9	negative selection	8422817
197418554	197418577	2	-	27260156	PANC0813	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.9450582768954734	[362]	[272,193,180,240]	-8	hSpCas9	negative selection	8422818
197421024	197421047	2	+	27260156	PANC0813	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.0270245469159796	[318]	[192,345,95,104]	-8	hSpCas9	negative selection	8422819
197434971	197434994	2	-	27260156	RDES	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.214098292750822	[571]	[109,106,159,206]	-9	hSpCas9	negative selection	8479814
197421096	197421119	2	-	27260156	RDES	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.9831256406436168	[988]	[439,560,653,678]	-9	hSpCas9	negative selection	8479815
197434964	197434987	2	+	27260156	RDES	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.8982362914228464	[724]	[313,503,574,404]	-9	hSpCas9	negative selection	8479816
197421028	197421051	2	-	27260156	RDES	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.0454397952239736	[452]	[195,254,277,291]	-9	hSpCas9	negative selection	8544068
197418554	197418577	2	-	27260156	RDES	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.9129245629150551	[362]	[162,212,305,213]	-9	hSpCas9	negative selection	8544069
197421024	197421047	2	+	27260156	RDES	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.316056372832933	[318]	[184,116,88,191]	-9	hSpCas9	negative selection	8544070
197434971	197434994	2	-	27260156	PC3	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.5988569394179146	[571]	[114,257,251,160]	-9	hSpCas9	negative selection	8601065
197421096	197421119	2	-	27260156	PC3	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	0.03759268046533348	[988]	[556,953,2169,929]	0	hSpCas9	negative selection	8601066
197434964	197434987	2	+	27260156	PC3	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.19116264260120697	[724]	[425,538,1055,709]	-4	hSpCas9	negative selection	8601067
197421028	197421051	2	-	27260156	PC3	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.8705481272183322	[452]	[133,131,550,328]	-9	hSpCas9	negative selection	8665319
197418554	197418577	2	-	27260156	PC3	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.486670188805667	[362]	[237,231,287,260]	-8	hSpCas9	negative selection	8665320
197421024	197421047	2	+	27260156	PC3	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.1658486983979497	[318]	[55,112,373,144]	-9	hSpCas9	negative selection	8665321
197434971	197434994	2	-	27260156	PATU8988T	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.1638539985522427	[571]	[278,305,302,90]	-9	hSpCas9	negative selection	8722316
197421096	197421119	2	-	27260156	PATU8988T	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-1.0645321811087598	[988]	[527,381,391,524]	-9	hSpCas9	negative selection	8722317
197434964	197434987	2	+	27260156	PATU8988T	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.485087166207174	[724]	[348,531,633,486]	-7	hSpCas9	negative selection	8722318
197421028	197421051	2	-	27260156	PATU8988T	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.2647644947497403	[452]	[102,199,62,381]	-9	hSpCas9	negative selection	8786570
197418554	197418577	2	-	27260156	PATU8988T	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.4498056745907622	[362]	[266,147,429,161]	-6	hSpCas9	negative selection	8786571
197421024	197421047	2	+	27260156	PATU8988T	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-0.48450485413648836	[318]	[99,167,473,122]	-7	hSpCas9	negative selection	8786572
197434971	197434994	2	-	27260156	T47D	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.027155024558064	[571]	[158,150,194,148]	-9	hSpCas9	negative selection	8843567
197421096	197421119	2	-	27260156	T47D	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.5890410127147139	[988]	[827,734,715,788]	-8	hSpCas9	negative selection	8843568
197434964	197434987	2	+	27260156	T47D	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.903974511852337	[724]	[451,402,476,477]	-9	hSpCas9	negative selection	8843569
197421028	197421051	2	-	27260156	T47D	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.1182865856867368	[452]	[219,226,241,285]	-9	hSpCas9	negative selection	8907821
197418554	197418577	2	-	27260156	T47D	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.2044567912481086	[362]	[166,187,180,197]	-9	hSpCas9	negative selection	8907822
197421024	197421047	2	+	27260156	T47D	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.4333973100523933	[318]	[122,124,143,159]	-9	hSpCas9	negative selection	8907823
197434971	197434994	2	-	27260156	SU8686	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.045977462029058	[571]	[96,136,121,207]	-9	hSpCas9	negative selection	8964818
197421096	197421119	2	-	27260156	SU8686	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-1.0792980644882166	[988]	[418,406,456,604]	-8	hSpCas9	negative selection	8964819
197434964	197434987	2	+	27260156	SU8686	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.1931984128968054	[724]	[290,300,338,331]	-9	hSpCas9	negative selection	8964820
197421028	197421051	2	-	27260156	SU8686	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.6643092967833009	[452]	[166,95,185,116]	-9	hSpCas9	negative selection	9029072
197418554	197418577	2	-	27260156	SU8686	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-1.1289398645501356	[362]	[73,154,220,230]	-8	hSpCas9	negative selection	9029073
197421024	197421047	2	+	27260156	SU8686	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.78696668210365	[318]	[87,82,72,128]	-9	hSpCas9	negative selection	9029074
197434971	197434994	2	-	27260156	SKES1	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.180480995979136	[571]	[331,292,229,174]	-9	hSpCas9	negative selection	9086069
197421096	197421119	2	-	27260156	SKES1	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.19567332817572403	[988]	[878,914,963,704]	-4	hSpCas9	negative selection	9086070
197434964	197434987	2	+	27260156	SKES1	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.4928433577683018	[724]	[740,447,510,388]	-8	hSpCas9	negative selection	9086071
197421028	197421051	2	-	27260156	SKES1	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.000845047174964	[452]	[196,288,183,233]	-9	hSpCas9	negative selection	9150323
197418554	197418577	2	-	27260156	SKES1	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.5599529759931479	[362]	[209,286,205,273]	-8	hSpCas9	negative selection	9150324
197421024	197421047	2	+	27260156	SKES1	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-0.6247048677678314	[318]	[259,181,229,160]	-8	hSpCas9	negative selection	9150325
197434971	197434994	2	-	27260156	TOV112D	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-0.8679469861045892	[571]	[228,486,313,261]	-9	hSpCas9	negative selection	9207320
197421096	197421119	2	-	27260156	TOV112D	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.2929295575020361	[988]	[760,1149,746,658]	-5	hSpCas9	negative selection	9207321
197434964	197434987	2	+	27260156	TOV112D	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.11835616494283152	[724]	[656,863,617,584]	-2	hSpCas9	negative selection	9207322
197421028	197421051	2	-	27260156	TOV112D	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.024925111753442038	[452]	[653,523,350,294]	0	hSpCas9	negative selection	9271574
197418554	197418577	2	-	27260156	TOV112D	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.3746475619742134	[362]	[244,394,174,329]	-6	hSpCas9	negative selection	9271575
197421024	197421047	2	+	27260156	TOV112D	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.1745074601203278	[318]	[76,151,152,179]	-9	hSpCas9	negative selection	9271576
197434971	197434994	2	-	27260156	TC71	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.474339641178737	[571]	[226,213,225,214]	-9	hSpCas9	negative selection	9328571
197421096	197421119	2	-	27260156	TC71	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.18467212417425827	[988]	[894,966,774,1110]	-5	hSpCas9	negative selection	9328572
197434964	197434987	2	+	27260156	TC71	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-0.4027088606761293	[724]	[540,620,631,554]	-8	hSpCas9	negative selection	9328573
197421028	197421051	2	-	27260156	TC71	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-1.0112353923200799	[452]	[293,183,236,247]	-9	hSpCas9	negative selection	9392825
197418554	197418577	2	-	27260156	TC71	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.28005081103661816	[362]	[368,306,313,288]	-6	hSpCas9	negative selection	9392826
197421024	197421047	2	+	27260156	TC71	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-0.70911267403512	[318]	[174,149,224,291]	-9	hSpCas9	negative selection	9392827
197434971	197434994	2	-	27260156	TC32	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-1.2120237250050043	[571]	[177,186,248,332]	-9	hSpCas9	negative selection	9449822
197421096	197421119	2	-	27260156	TC32	viability	TCATCATCTACGAGTTTGCTTGG	SF3B1	ENSG00000115524	-0.37762421893118303	[988]	[685,556,811,850]	-6	hSpCas9	negative selection	9449823
197434964	197434987	2	+	27260156	TC32	viability	CCGCTTACCTTCGTGAGTCTTGG	SF3B1	ENSG00000115524	-1.2025653339128253	[724]	[246,134,504,390]	-9	hSpCas9	negative selection	9449824
197421028	197421051	2	-	27260156	TC32	viability	TATACCACAGTCAACAGAACAGG	SF3B1	ENSG00000115524	-0.6081371093718211	[452]	[274,281,328,216]	-8	hSpCas9	negative selection	9514076
197418554	197418577	2	-	27260156	TC32	viability	CTGATCCTAAAATGAATGCTAGG	SF3B1	ENSG00000115524	-0.33455989970070593	[362]	[302,158,330,324]	-6	hSpCas9	negative selection	9514077
197421024	197421047	2	+	27260156	TC32	viability	ATCACCTGTTCTGTTGACTGTGG	SF3B1	ENSG00000115524	-1.158809338284395	[318]	[141,52,177,197]	-9	hSpCas9	negative selection	9514078
197408527	197408550	2	-	27869803	HPAFII	viability after 27 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-2.3580840965248875	[124]	[26,0,NaN]	-8	hSpCas9	negative selection	9572830
197409984	197410007	2	+	27869803	HPAFII	viability after 27 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-2.5729563675912672	[177]	[6,22,NaN]	-8	hSpCas9	negative selection	9572831
197420498	197420521	2	-	27869803	HPAFII	viability after 27 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-4.349647833040844	[207]	[0,8,NaN]	-9	hSpCas9	negative selection	9572832
197421081	197421104	2	-	27869803	HPAFII	viability after 27 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-3.183927860841287	[230]	[8,16,NaN]	-9	hSpCas9	negative selection	9572833
197423909	197423932	2	-	27869803	HPAFII	viability after 27 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-3.1437807125830193	[161]	[19,0,NaN]	-9	hSpCas9	negative selection	9572834
197434971	197434994	2	-	27869803	HPAFII	viability after 27 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.638050568093519	[154]	[5,0,NaN]	-9	hSpCas9	negative selection	9572835
197408527	197408550	2	-	27869803	HPAFII	viability after 15 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-3.4066594076588705	[124]	[24,4,NaN]	-9	hSpCas9	negative selection	9655279
197409984	197410007	2	+	27869803	HPAFII	viability after 15 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-3.6678975827811158	[177]	[27,6,NaN]	-9	hSpCas9	negative selection	9655280
197420498	197420521	2	-	27869803	HPAFII	viability after 15 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-4.407491584735974	[207]	[12,8,NaN]	-9	hSpCas9	negative selection	9655281
197421081	197421104	2	-	27869803	HPAFII	viability after 15 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.3287373554733248	[230]	[141,71,NaN]	-8	hSpCas9	negative selection	9655282
197423909	197423932	2	-	27869803	HPAFII	viability after 15 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-2.54879234333359	[161]	[75,0,NaN]	-9	hSpCas9	negative selection	9655283
197434971	197434994	2	-	27869803	HPAFII	viability after 15 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.5227330843788414	[154]	[73,0,NaN]	-9	hSpCas9	negative selection	9655284
197408527	197408550	2	-	27869803	ASPC1	viability after 36 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-1.9338155245078106	[302]	[13,4,54]	-9	hSpCas9	negative selection	9737728
197409984	197410007	2	+	27869803	ASPC1	viability after 36 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-1.749843290952093	[505]	[27,87,40]	-9	hSpCas9	negative selection	9737729
197420498	197420521	2	-	27869803	ASPC1	viability after 36 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	0.03315796096341378	[473]	[398,0,139]	0	hSpCas9	negative selection	9737730
197421081	197421104	2	-	27869803	ASPC1	viability after 36 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	0.8782090673187549	[399]	[176,263,303]	8	hSpCas9	negative selection	9737731
197423909	197423932	2	-	27869803	ASPC1	viability after 36 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-0.12273465186161969	[502]	[357,69,93]	-1	hSpCas9	negative selection	9737732
197434971	197434994	2	-	27869803	ASPC1	viability after 36 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.095289128351749	[565]	[0,28,4]	-9	hSpCas9	negative selection	9737733
197408527	197408550	2	-	27869803	PATU8988S	viability after 35 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-1.0284254288413135	[108]	[30,11,NaN]	-7	hSpCas9	negative selection	9820177
197409984	197410007	2	+	27869803	PATU8988S	viability after 35 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-3.1465440359179175	[384]	[21,12,NaN]	-9	hSpCas9	negative selection	9820178
197420498	197420521	2	-	27869803	PATU8988S	viability after 35 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-1.934217517694681	[393]	[50,31,NaN]	-9	hSpCas9	negative selection	9820179
197421081	197421104	2	-	27869803	PATU8988S	viability after 35 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.1162782463879113	[481]	[109,68,NaN]	-8	hSpCas9	negative selection	9820180
197423909	197423932	2	-	27869803	PATU8988S	viability after 35 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-1.69949335464843	[273]	[23,43,NaN]	-8	hSpCas9	negative selection	9820181
197434971	197434994	2	-	27869803	PATU8988S	viability after 35 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.406441950222234	[577]	[0,20,NaN]	-9	hSpCas9	negative selection	9820182
197408527	197408550	2	-	27869803	PATU8988S	viability after 31 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-0.4007968780136135	[108]	[35,28,NaN]	-4	hSpCas9	negative selection	9902626
197409984	197410007	2	+	27869803	PATU8988S	viability after 31 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-2.7235460004096095	[384]	[35,6,NaN]	-9	hSpCas9	negative selection	9902627
197420498	197420521	2	-	27869803	PATU8988S	viability after 31 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.4218964005238512	[393]	[16,44,NaN]	-9	hSpCas9	negative selection	9902628
197421081	197421104	2	-	27869803	PATU8988S	viability after 31 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-1.0990469275648014	[481]	[94,82,NaN]	-8	hSpCas9	negative selection	9902629
197423909	197423932	2	-	27869803	PATU8988S	viability after 31 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-2.0735178074251763	[273]	[10,44,NaN]	-9	hSpCas9	negative selection	9902630
197434971	197434994	2	-	27869803	PATU8988S	viability after 31 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.639181969628969	[577]	[14,64,NaN]	-9	hSpCas9	negative selection	9902631
197408527	197408550	2	-	27869803	HPAFII	viability after 35 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-1.6955181152199492	[124]	[35,0,NaN]	-7	hSpCas9	negative selection	9985075
197409984	197410007	2	+	27869803	HPAFII	viability after 35 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-5.5370592383493396	[177]	[0,2,NaN]	-9	hSpCas9	negative selection	9985076
197420498	197420521	2	-	27869803	HPAFII	viability after 35 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-6.718351165144417	[207]	[0,0,NaN]	-9	hSpCas9	negative selection	9985077
197421081	197421104	2	-	27869803	HPAFII	viability after 35 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-2.907942002070207	[230]	[0,31,NaN]	-8	hSpCas9	negative selection	9985078
197423909	197423932	2	-	27869803	HPAFII	viability after 35 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-2.2797214229011478	[161]	[30,0,NaN]	-8	hSpCas9	negative selection	9985079
197434971	197434994	2	-	27869803	HPAFII	viability after 35 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-6.294035852277563	[154]	[0,0,NaN]	-9	hSpCas9	negative selection	9985080
197408527	197408550	2	-	27869803	HPAFII	viability after 31 days	ACTCCTCGAACAGATCGAGGTGG	SF3B1	ENSG00000115524	-0.9442834881669262	[124]	[68,0,NaN]	-5	hSpCas9	negative selection	10067524
197409984	197410007	2	+	27869803	HPAFII	viability after 31 days	TAAGGAAGGAGTATGCCCAGGGG	SF3B1	ENSG00000115524	-3.5892508948315776	[177]	[14,0,NaN]	-9	hSpCas9	negative selection	10067525
197420498	197420521	2	-	27869803	HPAFII	viability after 31 days	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-6.867068518465834	[207]	[0,0,NaN]	-9	hSpCas9	negative selection	10067526
197421081	197421104	2	-	27869803	HPAFII	viability after 31 days	TTGCTTGGTCAGAAGAAGCCAGG	SF3B1	ENSG00000115524	-2.927282530990538	[230]	[17,15,NaN]	-8	hSpCas9	negative selection	10067527
197423909	197423932	2	-	27869803	HPAFII	viability after 31 days	TCTTGATGAAGCTCAAGGAGTGG	SF3B1	ENSG00000115524	-3.2042642158962824	[161]	[17,0,NaN]	-9	hSpCas9	negative selection	10067528
197434971	197434994	2	-	27869803	HPAFII	viability after 31 days	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.397110540043267	[154]	[6,0,NaN]	-9	hSpCas9	negative selection	10067529
197434971	197434994	2	-	28162770	P31FUJ	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.6790584343039425	[108]	[4]	-9	hSpCas9	negative selection	10232857
197423944	197423967	2	-	28162770	P31FUJ	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	0.2892725903513871	[632]	[908]	3	hSpCas9	negative selection	10232858
197423914	197423937	2	-	28162770	P31FUJ	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	0.9895902169220694	[14]	[34]	9	hSpCas9	negative selection	10232859
197420433	197420456	2	+	28162770	P31FUJ	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-0.9837746565744638	[68]	[40]	-6	hSpCas9	negative selection	10232860
197421064	197421087	2	-	28162770	P31FUJ	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.9635358448690703	[384]	[115]	-8	hSpCas9	negative selection	10232861
197420514	197420537	2	+	28162770	P31FUJ	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-0.6244392711131455	[264]	[201]	-5	hSpCas9	negative selection	10232862
197423845	197423868	2	-	28162770	P31FUJ	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.9232621119180346	[336]	[750]	9	hSpCas9	negative selection	10232863
197421050	197421073	2	+	28162770	P31FUJ	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-2.213943177163063	[607]	[153]	-8	hSpCas9	negative selection	10232864
197420498	197420521	2	-	28162770	P31FUJ	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.720248199221272	[285]	[50]	-9	hSpCas9	negative selection	10232865
197420447	197420470	2	+	28162770	P31FUJ	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	0.2407991873590735	[174]	[242]	2	hSpCas9	negative selection	10232866
197434971	197434994	2	-	28162770	TF1	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10402223
197423944	197423967	2	-	28162770	TF1	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	NaN	[NaN]	[651]	1	hSpCas9	negative selection	10402224
197423914	197423937	2	-	28162770	TF1	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10402225
197420433	197420456	2	+	28162770	TF1	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10402226
197421064	197421087	2	-	28162770	TF1	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10402227
197420514	197420537	2	+	28162770	TF1	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10402228
197423845	197423868	2	-	28162770	TF1	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	NaN	[NaN]	[383]	1	hSpCas9	negative selection	10402229
197421050	197421073	2	+	28162770	TF1	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10402230
197420498	197420521	2	-	28162770	TF1	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10402231
197420447	197420470	2	+	28162770	TF1	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10402232
197434971	197434994	2	-	28162770	SKM1	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-5.6293566200796095	[27]	[0]	-9	hSpCas9	negative selection	10571589
197423944	197423967	2	-	28162770	SKM1	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	-0.23325755675842264	[126]	[190]	-2	hSpCas9	negative selection	10571590
197423914	197423937	2	-	28162770	SKM1	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-1.9595052217719409	[10]	[4]	-8	hSpCas9	negative selection	10571591
197420433	197420456	2	+	28162770	SKM1	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-0.684498174272071	[9]	[10]	-5	hSpCas9	negative selection	10571592
197421064	197421087	2	-	28162770	SKM1	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.219965683941908	[111]	[84]	-7	hSpCas9	negative selection	10571593
197420514	197420537	2	+	28162770	SKM1	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-1.322899933954687	[74]	[52]	-7	hSpCas9	negative selection	10571594
197423845	197423868	2	-	28162770	SKM1	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.5977122884663115	[76]	[205]	6	hSpCas9	negative selection	10571595
197421050	197421073	2	+	28162770	SKM1	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-2.7168194613299486	[118]	[31]	-9	hSpCas9	negative selection	10571596
197420498	197420521	2	-	28162770	SKM1	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-5.866395817380459	[65]	[1]	-9	hSpCas9	negative selection	10571597
197420447	197420470	2	+	28162770	SKM1	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	-0.18728616210374993	[37]	[58]	-2	hSpCas9	negative selection	10571598
197434971	197434994	2	-	28162770	SKM1	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-5.6293566200796095	[27]	[0]	-9	hSpCas9	negative selection	10740955
197423944	197423967	2	-	28162770	SKM1	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	-0.23325755675842264	[126]	[190]	-2	hSpCas9	negative selection	10740956
197423914	197423937	2	-	28162770	SKM1	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-1.9595052217719409	[10]	[4]	-8	hSpCas9	negative selection	10740957
197420433	197420456	2	+	28162770	SKM1	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-0.684498174272071	[9]	[10]	-5	hSpCas9	negative selection	10740958
197421064	197421087	2	-	28162770	SKM1	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.219965683941908	[111]	[84]	-7	hSpCas9	negative selection	10740959
197420514	197420537	2	+	28162770	SKM1	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-1.322899933954687	[74]	[52]	-7	hSpCas9	negative selection	10740960
197423845	197423868	2	-	28162770	SKM1	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.5977122884663115	[76]	[205]	6	hSpCas9	negative selection	10740961
197421050	197421073	2	+	28162770	SKM1	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-2.7168194613299486	[118]	[31]	-9	hSpCas9	negative selection	10740962
197420498	197420521	2	-	28162770	SKM1	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-5.866395817380459	[65]	[1]	-9	hSpCas9	negative selection	10740963
197420447	197420470	2	+	28162770	SKM1	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	-0.18728616210374993	[37]	[58]	-2	hSpCas9	negative selection	10740964
197434971	197434994	2	-	28162770	PL21	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-5.568044710287607	[108]	[0]	-9	hSpCas9	negative selection	10910321
197423944	197423967	2	-	28162770	PL21	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	-0.08084746075797633	[468]	[192]	0	hSpCas9	negative selection	10910322
197423914	197423937	2	-	28162770	PL21	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-2.5003001036517727	[25]	[1]	-9	hSpCas9	negative selection	10910323
197420433	197420456	2	+	28162770	PL21	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	0.07085659754435336	[69]	[31]	0	hSpCas9	negative selection	10910324
197421064	197421087	2	-	28162770	PL21	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.6996089118751785	[402]	[53]	-8	hSpCas9	negative selection	10910325
197420514	197420537	2	+	28162770	PL21	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	0.7935143550266762	[227]	[171]	6	hSpCas9	negative selection	10910326
197423845	197423868	2	-	28162770	PL21	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.6041641210457462	[262]	[173]	5	hSpCas9	negative selection	10910327
197421050	197421073	2	+	28162770	PL21	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-1.8189187213263645	[380]	[46]	-8	hSpCas9	negative selection	10910328
197420498	197420521	2	-	28162770	PL21	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-1.099984110079694	[196]	[39]	-6	hSpCas9	negative selection	10910329
197420447	197420470	2	+	28162770	PL21	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	-1.6169963283608693	[147]	[20]	-8	hSpCas9	negative selection	10910330
197434971	197434994	2	-	28162770	P31FUJ	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.6790584343039425	[108]	[4]	-9	hSpCas9	negative selection	11079687
197423944	197423967	2	-	28162770	P31FUJ	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	0.2892725903513871	[632]	[908]	3	hSpCas9	negative selection	11079688
197423914	197423937	2	-	28162770	P31FUJ	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	0.9895902169220694	[14]	[34]	9	hSpCas9	negative selection	11079689
197420433	197420456	2	+	28162770	P31FUJ	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-0.9837746565744638	[68]	[40]	-6	hSpCas9	negative selection	11079690
197421064	197421087	2	-	28162770	P31FUJ	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.9635358448690703	[384]	[115]	-8	hSpCas9	negative selection	11079691
197420514	197420537	2	+	28162770	P31FUJ	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-0.6244392711131455	[264]	[201]	-5	hSpCas9	negative selection	11079692
197423845	197423868	2	-	28162770	P31FUJ	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.9232621119180346	[336]	[750]	9	hSpCas9	negative selection	11079693
197421050	197421073	2	+	28162770	P31FUJ	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-2.213943177163063	[607]	[153]	-8	hSpCas9	negative selection	11079694
197420498	197420521	2	-	28162770	P31FUJ	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.720248199221272	[285]	[50]	-9	hSpCas9	negative selection	11079695
197420447	197420470	2	+	28162770	P31FUJ	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	0.2407991873590735	[174]	[242]	2	hSpCas9	negative selection	11079696
197434971	197434994	2	-	28162770	OCIAML5	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.437029071585153	[41]	[13]	-8	hSpCas9	negative selection	11249053
197423944	197423967	2	-	28162770	OCIAML5	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	0.014931297621008977	[351]	[641]	0	hSpCas9	negative selection	11249054
197423914	197423937	2	-	28162770	OCIAML5	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-5.244383993642757	[20]	[0]	-9	hSpCas9	negative selection	11249055
197420433	197420456	2	+	28162770	OCIAML5	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-0.16617516129205967	[22]	[36]	-1	hSpCas9	negative selection	11249056
197421064	197421087	2	-	28162770	OCIAML5	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.6412994746471765	[177]	[102]	-7	hSpCas9	negative selection	11249057
197420514	197420537	2	+	28162770	OCIAML5	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-0.8132473219734688	[109]	[112]	-5	hSpCas9	negative selection	11249058
197423845	197423868	2	-	28162770	OCIAML5	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.3801920035956833	[228]	[537]	3	hSpCas9	negative selection	11249059
197421050	197421073	2	+	28162770	OCIAML5	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-2.3475309207460504	[374]	[132]	-8	hSpCas9	negative selection	11249060
197420498	197420521	2	-	28162770	OCIAML5	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.943989060305036	[161]	[37]	-8	hSpCas9	negative selection	11249061
197420447	197420470	2	+	28162770	OCIAML5	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	-1.1982422119980365	[149]	[117]	-6	hSpCas9	negative selection	11249062
197434971	197434994	2	-	28162770	EOL1	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-5.134345917483034	[199]	[2]	-9	hSpCas9	negative selection	11418419
197423944	197423967	2	-	28162770	EOL1	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	0.16344203180841155	[682]	[402]	1	hSpCas9	negative selection	11418420
197423914	197423937	2	-	28162770	EOL1	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-0.9897223544035816	[48]	[12]	-6	hSpCas9	negative selection	11418421
197420433	197420456	2	+	28162770	EOL1	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-1.3862397657116274	[128]	[25]	-7	hSpCas9	negative selection	11418422
197421064	197421087	2	-	28162770	EOL1	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.7420284947042737	[799]	[125]	-8	hSpCas9	negative selection	11418423
197420514	197420537	2	+	28162770	EOL1	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-0.4280771205397444	[474]	[185]	-3	hSpCas9	negative selection	11418424
197423845	197423868	2	-	28162770	EOL1	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.41104763340600264	[383]	[268]	4	hSpCas9	negative selection	11418425
197421050	197421073	2	+	28162770	EOL1	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-4.240917581681078	[645]	[17]	-9	hSpCas9	negative selection	11418426
197420498	197420521	2	-	28162770	EOL1	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-1.259876799566893	[249]	[54]	-7	hSpCas9	negative selection	11418427
197420447	197420470	2	+	28162770	EOL1	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	0.6152197134628058	[170]	[137]	5	hSpCas9	negative selection	11418428
197434971	197434994	2	-	28162770	MOLM13	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.8540387133427836	[179]	[17]	-8	hSpCas9	negative selection	11587785
197423944	197423967	2	-	28162770	MOLM13	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	-0.46369037290633974	[802]	[420]	-3	hSpCas9	negative selection	11587786
197423914	197423937	2	-	28162770	MOLM13	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	1.6629053639497215	[37]	[86]	9	hSpCas9	negative selection	11587787
197420433	197420456	2	+	28162770	MOLM13	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-2.5765047378138743	[98]	[11]	-8	hSpCas9	negative selection	11587788
197421064	197421087	2	-	28162770	MOLM13	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.526835676414747	[545]	[136]	-6	hSpCas9	negative selection	11587789
197420514	197420537	2	+	28162770	MOLM13	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	0.12921802282264008	[324]	[256]	0	hSpCas9	negative selection	11587790
197423845	197423868	2	-	28162770	MOLM13	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.597172398489545	[383]	[419]	4	hSpCas9	negative selection	11587791
197421050	197421073	2	+	28162770	MOLM13	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-3.1639397242145515	[656]	[52]	-8	hSpCas9	negative selection	11587792
197420498	197420521	2	-	28162770	MOLM13	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.8327700965891323	[403]	[40]	-8	hSpCas9	negative selection	11587793
197420447	197420470	2	+	28162770	MOLM13	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	-1.2976453648183983	[203]	[59]	-6	hSpCas9	negative selection	11587794
197434971	197434994	2	-	28162770	HEL	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-6.2761244052742375	[120]	[0]	-9	hSpCas9	negative selection	11757151
197423944	197423967	2	-	28162770	HEL	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	-0.13825138605784715	[731]	[425]	-1	hSpCas9	negative selection	11757152
197423914	197423937	2	-	28162770	HEL	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-4.849114264329318	[44]	[0]	-9	hSpCas9	negative selection	11757153
197420433	197420456	2	+	28162770	HEL	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-0.8202331443421889	[101]	[36]	-5	hSpCas9	negative selection	11757154
197421064	197421087	2	-	28162770	HEL	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-2.14385752989045	[413]	[59]	-8	hSpCas9	negative selection	11757155
197420514	197420537	2	+	28162770	HEL	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-0.7409654604736953	[333]	[127]	-5	hSpCas9	negative selection	11757156
197423845	197423868	2	-	28162770	HEL	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.47281383055804455	[287]	[255]	4	hSpCas9	negative selection	11757157
197421050	197421073	2	+	28162770	HEL	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-5.507008287504325	[638]	[8]	-9	hSpCas9	negative selection	11757158
197420498	197420521	2	-	28162770	HEL	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-5.496812520398437	[281]	[3]	-9	hSpCas9	negative selection	11757159
197420447	197420470	2	+	28162770	HEL	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	-0.7507425239120394	[154]	[58]	-5	hSpCas9	negative selection	11757160
197434971	197434994	2	-	28162770	MV411	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.3202469585065453	[82]	[13]	-8	hSpCas9	negative selection	11926517
197423944	197423967	2	-	28162770	MV411	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	0.9853159542428868	[315]	[526]	8	hSpCas9	negative selection	11926518
197423914	197423937	2	-	28162770	MV411	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-1.5599173712748287	[13]	[3]	-7	hSpCas9	negative selection	11926519
197420433	197420456	2	+	28162770	MV411	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-1.147422066558438	[70]	[26]	-6	hSpCas9	negative selection	11926520
197421064	197421087	2	-	28162770	MV411	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-2.722188800173706	[422]	[53]	-9	hSpCas9	negative selection	11926521
197420514	197420537	2	+	28162770	MV411	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	0.05242156837763247	[173]	[151]	0	hSpCas9	negative selection	11926522
197423845	197423868	2	-	28162770	MV411	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.3692562950765379	[226]	[246]	3	hSpCas9	negative selection	11926523
197421050	197421073	2	+	28162770	MV411	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-2.1372262994525495	[422]	[80]	-8	hSpCas9	negative selection	11926524
197420498	197420521	2	-	28162770	MV411	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.717458648261309	[202]	[25]	-9	hSpCas9	negative selection	11926525
197420447	197420470	2	+	28162770	MV411	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	0.45097094486790734	[65]	[75]	4	hSpCas9	negative selection	11926526
197434971	197434994	2	-	28162770	MONOMAC1	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-3.9195028715306446	[65]	[4]	-9	hSpCas9	negative selection	12095883
197423944	197423967	2	-	28162770	MONOMAC1	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	-0.18132676397089187	[273]	[276]	-1	hSpCas9	negative selection	12095884
197423914	197423937	2	-	28162770	MONOMAC1	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-1.5596069264442614	[17]	[6]	-8	hSpCas9	negative selection	12095885
197420433	197420456	2	+	28162770	MONOMAC1	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-1.78199934778071	[38]	[12]	-8	hSpCas9	negative selection	12095886
197421064	197421087	2	-	28162770	MONOMAC1	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.102296357089144	[220]	[117]	-7	hSpCas9	negative selection	12095887
197420514	197420537	2	+	28162770	MONOMAC1	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-1.1095740058092143	[159]	[84]	-7	hSpCas9	negative selection	12095888
197423845	197423868	2	-	28162770	MONOMAC1	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.21800065221929027	[152]	[203]	2	hSpCas9	negative selection	12095889
197421050	197421073	2	+	28162770	MONOMAC1	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-0.9935034529744218	[263]	[151]	-7	hSpCas9	negative selection	12095890
197420498	197420521	2	-	28162770	MONOMAC1	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-0.5549304392347887	[131]	[102]	-5	hSpCas9	negative selection	12095891
197420447	197420470	2	+	28162770	MONOMAC1	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	-1.3896819250019496	[79]	[34]	-8	hSpCas9	negative selection	12095892
197434971	197434994	2	-	28162770	OCIAML2	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-4.108059745857453	[27]	[8]	-9	hSpCas9	negative selection	12265249
197423944	197423967	2	-	28162770	OCIAML2	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	0.34321885890094306	[94]	[667]	3	hSpCas9	negative selection	12265250
197423914	197423937	2	-	28162770	OCIAML2	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-1.371094151691247	[6]	[14]	-7	hSpCas9	negative selection	12265251
197420433	197420456	2	+	28162770	OCIAML2	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-0.18522760637991276	[7]	[38]	-1	hSpCas9	negative selection	12265252
197421064	197421087	2	-	28162770	OCIAML2	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-1.885667324521005	[49]	[74]	-8	hSpCas9	negative selection	12265253
197420514	197420537	2	+	28162770	OCIAML2	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-0.04741839451761731	[43]	[235]	0	hSpCas9	negative selection	12265254
197423845	197423868	2	-	28162770	OCIAML2	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.8183478478439147	[61]	[605]	7	hSpCas9	negative selection	12265255
197421050	197421073	2	+	28162770	OCIAML2	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-3.0461319967142506	[75]	[50]	-9	hSpCas9	negative selection	12265256
197420498	197420521	2	-	28162770	OCIAML2	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-2.5347601626618768	[45]	[43]	-8	hSpCas9	negative selection	12265257
197420447	197420470	2	+	28162770	OCIAML2	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	-0.36629316542742574	[19]	[85]	-3	hSpCas9	negative selection	12265258
197434971	197434994	2	-	28162770	OCIAML3	viability	AAGATCGCCAAGACTCACGAAGG	SF3B1	ENSG00000115524	-2.676469800516136	[35]	[16]	-9	hSpCas9	negative selection	12434615
197423944	197423967	2	-	28162770	OCIAML3	viability	GCACAGATTCGAGAAATTCAAGG	SF3B1	ENSG00000115524	-0.6174666131481521	[123]	[243]	-5	hSpCas9	negative selection	12434616
197423914	197423937	2	-	28162770	OCIAML3	viability	GCAGCTCTTGATGAAGCTCAAGG	SF3B1	ENSG00000115524	-0.5236183124327654	[9]	[20]	-4	hSpCas9	negative selection	12434617
197420433	197420456	2	+	28162770	OCIAML3	viability	GCAAAAGGATCAAGACGCTCTGG	SF3B1	ENSG00000115524	-0.4335429681309171	[16]	[37]	-3	hSpCas9	negative selection	12434618
197421064	197421087	2	-	28162770	OCIAML3	viability	GCCAGGATATCATGCCCCTGTGG	SF3B1	ENSG00000115524	-3.5608407763889636	[128]	[32]	-9	hSpCas9	negative selection	12434619
197420514	197420537	2	+	28162770	OCIAML3	viability	GGAGGTCTGTGCTCAGCAAATGG	SF3B1	ENSG00000115524	-0.42735777091471183	[48]	[109]	-3	hSpCas9	negative selection	12434620
197423845	197423868	2	-	28162770	OCIAML3	viability	GGAAGTGACAGCAGATTTGCTGG	SF3B1	ENSG00000115524	0.011418962956708745	[69]	[212]	0	hSpCas9	negative selection	12434621
197421050	197421073	2	+	28162770	OCIAML3	viability	ATCATTAAGCAATGCCACAGGGG	SF3B1	ENSG00000115524	-3.213735559205996	[125]	[40]	-9	hSpCas9	negative selection	12434622
197420498	197420521	2	-	28162770	OCIAML3	viability	GACCTCCAAAGATTGCAGACCGG	SF3B1	ENSG00000115524	-3.2016902175454027	[63]	[20]	-9	hSpCas9	negative selection	12434623
197420447	197420470	2	+	28162770	OCIAML3	viability	ACGCTCTGGGGAAATTATCATGG	SF3B1	ENSG00000115524	0.6521529469452343	[42]	[203]	6	hSpCas9	negative selection	12434624