Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:51804
• Symbol:Six4
• Description:SIX homeobox 4

DataSource: http://genomecrispr.dkfz.de/#!/results/Six4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
60723966	60723989	14	-	26472758	Jiyoye	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	-0.9770897689781537	[200]	[76]	-6	hSpCas9	negative selection	147151
60723250	60723273	14	-	26472758	Jiyoye	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	0.3350255957500381	[40]	[38]	2	hSpCas9	negative selection	147152
60724032	60724055	14	-	26472758	Jiyoye	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	-1.0106771333800244	[170]	[63]	-6	hSpCas9	negative selection	147153
60723996	60724019	14	-	26472758	Jiyoye	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	-0.007862117772970523	[55]	[41]	0	hSpCas9	negative selection	147154
60723858	60723881	14	-	26472758	Jiyoye	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-5.493691426474875	[238]	[3]	-9	hSpCas9	negative selection	147155
60723706	60723729	14	-	26472758	Jiyoye	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	0.2551722880608236	[19]	[17]	2	hSpCas9	negative selection	147156
60723582	60723605	14	+	26472758	Jiyoye	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	-0.031266722107914174	[144]	[106]	0	hSpCas9	negative selection	147157
60723540	60723563	14	+	26472758	Jiyoye	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.20195024331429512	[180]	[156]	1	hSpCas9	negative selection	147158
60723519	60723542	14	+	26472758	Jiyoye	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	0.11766876431088846	[10]	[8]	0	hSpCas9	negative selection	147159
60723495	60723518	14	-	26472758	Jiyoye	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	1.2696718577559385	[10]	[19]	7	hSpCas9	negative selection	147160
60723966	60723989	14	-	26472758	KBM7	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	-0.0261808638692419	[379,245]	[206,83]	0	hSpCas9	negative selection	338269
60723250	60723273	14	-	26472758	KBM7	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	0.37036950965755877	[103,171]	[59,109]	4	hSpCas9	negative selection	338270
60724032	60724055	14	-	26472758	KBM7	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.28926418719562486	[279,304]	[157,179]	3	hSpCas9	negative selection	338271
60723996	60724019	14	-	26472758	KBM7	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.1589715130351974	[357,214]	[103,185]	1	hSpCas9	negative selection	338272
60723858	60723881	14	-	26472758	KBM7	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-3.104218794075297	[1368,809]	[80,37]	-9	hSpCas9	negative selection	338273
60723706	60723729	14	-	26472758	KBM7	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	0.6841004550419558	[138,116]	[61,126]	7	hSpCas9	negative selection	338274
60723582	60723605	14	+	26472758	KBM7	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.5035238420589688	[389,259]	[113,301]	5	hSpCas9	negative selection	338275
60723540	60723563	14	+	26472758	KBM7	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	-0.01725722933502738	[789,641]	[325,334]	0	hSpCas9	negative selection	338276
60723519	60723542	14	+	26472758	KBM7	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	0.8812217104411262	[75,73]	[23,101]	8	hSpCas9	negative selection	338277
60723495	60723518	14	-	26472758	KBM7	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	1.0097988507603242	[84,88]	[26,132]	9	hSpCas9	negative selection	338278
60723966	60723989	14	-	26472758	Raji	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	-0.15357654222233608	[138]	[28]	-1	hSpCas9	negative selection	529387
60723250	60723273	14	-	26472758	Raji	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	0.06924840648682828	[114]	[27]	0	hSpCas9	negative selection	529388
60724032	60724055	14	-	26472758	Raji	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.3704179412073932	[199]	[59]	3	hSpCas9	negative selection	529389
60723996	60724019	14	-	26472758	Raji	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.08501572234514498	[129]	[31]	0	hSpCas9	negative selection	529390
60723858	60723881	14	-	26472758	Raji	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-4.550827947378195	[403]	[3]	-9	hSpCas9	negative selection	529391
60723706	60723729	14	-	26472758	Raji	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	-0.14054397806998598	[37]	[7]	-1	hSpCas9	negative selection	529392
60723582	60723605	14	+	26472758	Raji	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	-0.5009618927855075	[310]	[50]	-4	hSpCas9	negative selection	529393
60723540	60723563	14	+	26472758	Raji	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.03030731235495876	[345]	[81]	0	hSpCas9	negative selection	529394
60723519	60723542	14	+	26472758	Raji	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	-2.3844695609560755	[44]	[1]	-9	hSpCas9	negative selection	529395
60723495	60723518	14	-	26472758	Raji	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	1.4293116302609619	[15]	[9]	9	hSpCas9	negative selection	529396
60723966	60723989	14	-	26472758	K562	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	-1.1197750941979254	[380]	[147]	-6	hSpCas9	negative selection	720505
60723250	60723273	14	-	26472758	K562	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	0.10609057111847342	[174]	[158]	0	hSpCas9	negative selection	720506
60724032	60724055	14	-	26472758	K562	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.4805936734342984	[252]	[297]	4	hSpCas9	negative selection	720507
60723996	60724019	14	-	26472758	K562	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.4625988977159805	[195]	[227]	3	hSpCas9	negative selection	720508
60723858	60723881	14	-	26472758	K562	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-5.208440237047364	[875]	[19]	-9	hSpCas9	negative selection	720509
60723706	60723729	14	-	26472758	K562	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	0.6350031832207517	[118]	[155]	5	hSpCas9	negative selection	720510
60723582	60723605	14	+	26472758	K562	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.2267708618470223	[328]	[324]	1	hSpCas9	negative selection	720511
60723540	60723563	14	+	26472758	K562	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	1.2873045405196233	[347]	[716]	9	hSpCas9	negative selection	720512
60723519	60723542	14	+	26472758	K562	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	0.5632409116859873	[92]	[115]	4	hSpCas9	negative selection	720513
60723495	60723518	14	-	26472758	K562	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	-0.7031138524394174	[53]	[27]	-4	hSpCas9	negative selection	720514
60713430	60713453	14	-	26627737	DLD1	viability	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.24010725360176932	[558]	[142,111,181]	-3	hSpCas9	negative selection	788948
60714082	60714105	14	+	26627737	DLD1	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.12115865033349377	[639]	[178,275,111]	-1	hSpCas9	negative selection	788949
60720318	60720341	14	+	26627737	DLD1	viability	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	0.8397684962174563	[495]	[313,321,208]	7	hSpCas9	negative selection	788950
60723439	60723462	14	-	26627737	DLD1	viability	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	-0.08569651479788118	[409]	[59,136,159]	-1	hSpCas9	negative selection	788951
60723456	60723479	14	+	26627737	DLD1	viability	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-1.0399038415820856	[340]	[72,43,39]	-7	hSpCas9	negative selection	788952
60723987	60724010	14	-	26627737	DLD1	viability	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.31256671438616435	[56]	[53,0,11]	3	hSpCas9	negative selection	788953
60713430	60713453	14	-	26627737	GBM cells	viability after 5 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.5937445215156321	[279]	[121,76]	-7	hSpCas9	negative selection	871263
60714082	60714105	14	+	26627737	GBM cells	viability after 5 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.8032305268303779	[186]	[184,164]	9	hSpCas9	negative selection	871264
60720318	60720341	14	+	26627737	GBM cells	viability after 5 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	0.05419210036359645	[483]	[250,287]	0	hSpCas9	negative selection	871265
60723439	60723462	14	-	26627737	GBM cells	viability after 5 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.1430668149609443	[140]	[73,92]	2	hSpCas9	negative selection	871266
60723456	60723479	14	+	26627737	GBM cells	viability after 5 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	0.06766833262006033	[136]	[57,95]	1	hSpCas9	negative selection	871267
60723987	60724010	14	-	26627737	GBM cells	viability after 5 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.2754772263498937	[56]	[44,28]	4	hSpCas9	negative selection	871268
60713430	60713453	14	-	26627737	GBM cells	viability after 13 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.20415244824957812	[279]	[206,148]	2	hSpCas9	negative selection	953578
60714082	60714105	14	+	26627737	GBM cells	viability after 13 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.48644910186819645	[186]	[161,125]	6	hSpCas9	negative selection	953579
60720318	60720341	14	+	26627737	GBM cells	viability after 13 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.2387172251542321	[483]	[237,209]	-3	hSpCas9	negative selection	953580
60723439	60723462	14	-	26627737	GBM cells	viability after 13 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.25418816764080276	[140]	[93,88]	3	hSpCas9	negative selection	953581
60723456	60723479	14	+	26627737	GBM cells	viability after 13 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.18964963458323036	[136]	[73,57]	-2	hSpCas9	negative selection	953582
60723987	60724010	14	-	26627737	GBM cells	viability after 13 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.40702382380400426	[56]	[56,27]	5	hSpCas9	negative selection	953583
60713430	60713453	14	-	26627737	GBM cells	viability after 21 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.37827403205707155	[279]	[127,106]	-3	hSpCas9	negative selection	1035893
60714082	60714105	14	+	26627737	GBM cells	viability after 21 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.09225685124939859	[186]	[99,90]	-1	hSpCas9	negative selection	1035894
60720318	60720341	14	+	26627737	GBM cells	viability after 21 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	0.15437514295361943	[483]	[300,284]	1	hSpCas9	negative selection	1035895
60723439	60723462	14	-	26627737	GBM cells	viability after 21 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.05779302580645118	[140]	[85,73]	0	hSpCas9	negative selection	1035896
60723456	60723479	14	+	26627737	GBM cells	viability after 21 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	0.4618376973911129	[136]	[113,91]	5	hSpCas9	negative selection	1035897
60723987	60724010	14	-	26627737	GBM cells	viability after 21 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.38798467345735466	[56]	[39,40]	4	hSpCas9	negative selection	1035898
60713430	60713453	14	-	26627737	RPE1	viability after 9 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.7227348145626551	[1078]	[236,162]	-5	hSpCas9	negative selection	1118208
60714082	60714105	14	+	26627737	RPE1	viability after 9 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	1.8158965049923932	[180]	[171,234]	8	hSpCas9	negative selection	1118209
60720318	60720341	14	+	26627737	RPE1	viability after 9 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	0.6355246476249348	[722]	[386,305]	4	hSpCas9	negative selection	1118210
60723439	60723462	14	-	26627737	RPE1	viability after 9 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.2908088772318325	[473]	[229,118]	2	hSpCas9	negative selection	1118211
60723456	60723479	14	+	26627737	RPE1	viability after 9 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.8038872113746436	[604]	[135,72]	-5	hSpCas9	negative selection	1118212
60723987	60724010	14	-	26627737	RPE1	viability after 9 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	-0.9303653567287613	[320]	[43,63]	-6	hSpCas9	negative selection	1118213
60713430	60713453	14	-	26627737	RPE1	viability after 12 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.35136729917143067	[1078]	[234,218]	-2	hSpCas9	negative selection	1200523
60714082	60714105	14	+	26627737	RPE1	viability after 12 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	1.2997170362316801	[180]	[143,93]	7	hSpCas9	negative selection	1200524
60720318	60720341	14	+	26627737	RPE1	viability after 12 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	1.01821749679938	[722]	[322,467]	6	hSpCas9	negative selection	1200525
60723439	60723462	14	-	26627737	RPE1	viability after 12 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.3168769984081733	[473]	[196,117]	2	hSpCas9	negative selection	1200526
60723456	60723479	14	+	26627737	RPE1	viability after 12 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-1.2541893865409117	[604]	[38,98]	-7	hSpCas9	negative selection	1200527
60723987	60724010	14	-	26627737	RPE1	viability after 12 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	-1.8871757504226365	[320]	[16,29]	-8	hSpCas9	negative selection	1200528
60713430	60713453	14	-	26627737	RPE1	viability after 15 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.027313344641229753	[1078]	[363,259]	0	hSpCas9	negative selection	1282838
60714082	60714105	14	+	26627737	RPE1	viability after 15 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	1.0318834425868744	[180]	[93,114]	6	hSpCas9	negative selection	1282839
60720318	60720341	14	+	26627737	RPE1	viability after 15 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	0.7718591286113755	[722]	[280,414]	5	hSpCas9	negative selection	1282840
60723439	60723462	14	-	26627737	RPE1	viability after 15 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.8057536173484657	[473]	[296,173]	5	hSpCas9	negative selection	1282841
60723456	60723479	14	+	26627737	RPE1	viability after 15 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.7968249622592565	[604]	[125,71]	-5	hSpCas9	negative selection	1282842
60723987	60724010	14	-	26627737	RPE1	viability after 15 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	-0.7654727515258353	[320]	[29,75]	-5	hSpCas9	negative selection	1282843
60713430	60713453	14	-	26627737	RPE1	viability after 18 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.4508765828052874	[1078]	[213,211]	-3	hSpCas9	negative selection	1365153
60714082	60714105	14	+	26627737	RPE1	viability after 18 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	1.9276204111864224	[180]	[238,128]	8	hSpCas9	negative selection	1365154
60720318	60720341	14	+	26627737	RPE1	viability after 18 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	1.0672718468513906	[722]	[360,459]	6	hSpCas9	negative selection	1365155
60723439	60723462	14	-	26627737	RPE1	viability after 18 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.8983260383102718	[473]	[279,193]	5	hSpCas9	negative selection	1365156
60723456	60723479	14	+	26627737	RPE1	viability after 18 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.9562845208600654	[604]	[0,172]	-5	hSpCas9	negative selection	1365157
60723987	60724010	14	-	26627737	RPE1	viability after 18 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	-1.5484507909669425	[320]	[32,25]	-7	hSpCas9	negative selection	1365158
60713430	60713453	14	-	26627737	HeLa	viability after 8 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.8674293647822051	[242]	[293,69,233]	7	hSpCas9	negative selection	1447468
60714082	60714105	14	+	26627737	HeLa	viability after 8 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	2.064987062617501	[115]	[288,109,248]	9	hSpCas9	negative selection	1447469
60720318	60720341	14	+	26627737	HeLa	viability after 8 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	0.3966060714347164	[647]	[236,282,550]	3	hSpCas9	negative selection	1447470
60723439	60723462	14	-	26627737	HeLa	viability after 8 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.40969003787164826	[280]	[357,93,83]	4	hSpCas9	negative selection	1447471
60723456	60723479	14	+	26627737	HeLa	viability after 8 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.18007311173388663	[383]	[320,135,31]	-2	hSpCas9	negative selection	1447472
60723987	60724010	14	-	26627737	HeLa	viability after 8 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.7681996889223708	[65]	[2,104,29]	6	hSpCas9	negative selection	1447473
60713430	60713453	14	-	26627737	HeLa	viability after 12 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.09714756578804362	[242]	[44,29,211]	-1	hSpCas9	negative selection	1529783
60714082	60714105	14	+	26627737	HeLa	viability after 12 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	1.3770177562825932	[115]	[72,256,27]	8	hSpCas9	negative selection	1529784
60720318	60720341	14	+	26627737	HeLa	viability after 12 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	0.21696232366890578	[647]	[365,257,316]	2	hSpCas9	negative selection	1529785
60723439	60723462	14	-	26627737	HeLa	viability after 12 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.7745829993188423	[280]	[181,174,240]	6	hSpCas9	negative selection	1529786
60723456	60723479	14	+	26627737	HeLa	viability after 12 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.08944038370794341	[383]	[205,36,217]	0	hSpCas9	negative selection	1529787
60723987	60724010	14	-	26627737	HeLa	viability after 12 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.8656048624371944	[65]	[0,74,68]	6	hSpCas9	negative selection	1529788
60713430	60713453	14	-	26627737	HeLa	viability after 15 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.03418817642752059	[242]	[127,81,77]	0	hSpCas9	negative selection	1612098
60714082	60714105	14	+	26627737	HeLa	viability after 15 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	2.217458286954642	[115]	[221,311,116]	9	hSpCas9	negative selection	1612099
60720318	60720341	14	+	26627737	HeLa	viability after 15 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.20836507937040605	[647]	[231,259,189]	-2	hSpCas9	negative selection	1612100
60723439	60723462	14	-	26627737	HeLa	viability after 15 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	1.1366513013981978	[280]	[141,325,290]	7	hSpCas9	negative selection	1612101
60723456	60723479	14	+	26627737	HeLa	viability after 15 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.2918953464486298	[383]	[208,93,74]	-3	hSpCas9	negative selection	1612102
60723987	60724010	14	-	26627737	HeLa	viability after 15 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.8282938007142229	[65]	[53,65,20]	6	hSpCas9	negative selection	1612103
60713430	60713453	14	-	26627737	HeLa	viability after 18 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.11959875153731503	[242]	[78,62,77]	-1	hSpCas9	negative selection	1694413
60714082	60714105	14	+	26627737	HeLa	viability after 18 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	2.2401416197407813	[115]	[155,257,116]	9	hSpCas9	negative selection	1694414
60720318	60720341	14	+	26627737	HeLa	viability after 18 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.1632556305918046	[647]	[161,224,189]	-1	hSpCas9	negative selection	1694415
60723439	60723462	14	-	26627737	HeLa	viability after 18 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	1.130070944602668	[280]	[92,269,290]	7	hSpCas9	negative selection	1694416
60723456	60723479	14	+	26627737	HeLa	viability after 18 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.3725183847443198	[383]	[128,74,74]	-3	hSpCas9	negative selection	1694417
60723987	60724010	14	-	26627737	HeLa	viability after 18 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.8688843181620485	[65]	[36,56,20]	6	hSpCas9	negative selection	1694418
60713430	60713453	14	-	26627737	HCT116	viability after 6 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	1.453285085558277	[510]	[228,214]	7	hSpCas9	negative selection	1776728
60714082	60714105	14	+	26627737	HCT116	viability after 6 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.5421833879068291	[882]	[40,290]	3	hSpCas9	negative selection	1776729
60720318	60720341	14	+	26627737	HCT116	viability after 6 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.49405816835595573	[633]	[131,36]	-3	hSpCas9	negative selection	1776730
60723439	60723462	14	-	26627737	HCT116	viability after 6 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	-0.697734607287486	[888]	[158,45]	-4	hSpCas9	negative selection	1776731
60723456	60723479	14	+	26627737	HCT116	viability after 6 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	2.7242214207248496	[180]	[421,58]	9	hSpCas9	negative selection	1776732
60723987	60724010	14	-	26627737	HCT116	viability after 6 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	-0.2428578266399517	[189]	[41,15]	-1	hSpCas9	negative selection	1776733
60713430	60713453	14	-	26627737	HCT116	viability after 8 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.060941940023435975	[326]	[237,239,87]	0	hSpCas9	negative selection	1859043
60714082	60714105	14	+	26627737	HCT116	viability after 8 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.105857511165926	[277]	[150,153,188]	1	hSpCas9	negative selection	1859044
60720318	60720341	14	+	26627737	HCT116	viability after 8 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.446720838550673	[739]	[233,332,328]	-5	hSpCas9	negative selection	1859045
60723439	60723462	14	-	26627737	HCT116	viability after 8 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	-0.7931940465894939	[368]	[82,118,148]	-7	hSpCas9	negative selection	1859046
60723456	60723479	14	+	26627737	HCT116	viability after 8 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.17209797111379704	[225]	[97,92,139]	-2	hSpCas9	negative selection	1859047
60723987	60724010	14	-	26627737	HCT116	viability after 8 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.7847992589063646	[43]	[65,38,20]	7	hSpCas9	negative selection	1859048
60713430	60713453	14	-	26627737	HCT116	viability after 9 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.2268924710799819	[510]	[238,96]	1	hSpCas9	negative selection	1941358
60714082	60714105	14	+	26627737	HCT116	viability after 9 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.2982817791329543	[882]	[198,185]	-2	hSpCas9	negative selection	1941359
60720318	60720341	14	+	26627737	HCT116	viability after 9 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	0.61801845899214	[633]	[189,314]	4	hSpCas9	negative selection	1941360
60723439	60723462	14	-	26627737	HCT116	viability after 9 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	-0.050484494552919645	[888]	[126,309]	0	hSpCas9	negative selection	1941361
60723456	60723479	14	+	26627737	HCT116	viability after 9 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	1.995376919972564	[180]	[61,295]	9	hSpCas9	negative selection	1941362
60723987	60724010	14	-	26627737	HCT116	viability after 9 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	-0.5463923270976236	[189]	[41,28]	-4	hSpCas9	negative selection	1941363
60713430	60713453	14	-	26627737	HCT116	viability after 12 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.24321605303324537	[326]	[161,182,89]	-3	hSpCas9	negative selection	2023673
60714082	60714105	14	+	26627737	HCT116	viability after 12 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.5150067251790289	[277]	[264,151,202]	5	hSpCas9	negative selection	2023674
60720318	60720341	14	+	26627737	HCT116	viability after 12 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.8115157573168156	[739]	[148,298,224]	-7	hSpCas9	negative selection	2023675
60723439	60723462	14	-	26627737	HCT116	viability after 12 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	-1.153133880426187	[368]	[55,114,93]	-8	hSpCas9	negative selection	2023676
60723456	60723479	14	+	26627737	HCT116	viability after 12 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.4272558989101208	[225]	[82,69,111]	-4	hSpCas9	negative selection	2023677
60723987	60724010	14	-	26627737	HCT116	viability after 12 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	1.0084323465911165	[43]	[38,78,22]	8	hSpCas9	negative selection	2023678
60713430	60713453	14	-	26627737	HCT116	viability after 15 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.15618858715748443	[326]	[191,194,121]	-2	hSpCas9	negative selection	2105988
60714082	60714105	14	+	26627737	HCT116	viability after 15 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.8185758522321489	[277]	[351,194,305]	7	hSpCas9	negative selection	2105989
60720318	60720341	14	+	26627737	HCT116	viability after 15 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.5316523635206791	[739]	[252,249,372]	-5	hSpCas9	negative selection	2105990
60723439	60723462	14	-	26627737	HCT116	viability after 15 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	-0.5116589976579051	[368]	[230,80,143]	-5	hSpCas9	negative selection	2105991
60723456	60723479	14	+	26627737	HCT116	viability after 15 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.30435178723022	[225]	[101,29,181]	-3	hSpCas9	negative selection	2105992
60723987	60724010	14	-	26627737	HCT116	viability after 15 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.35977789487956047	[43]	[28,46,20]	3	hSpCas9	negative selection	2105993
60713430	60713453	14	-	26627737	HCT116	viability after 18 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.13368323216529046	[326]	[179,181,156]	1	hSpCas9	negative selection	2188303
60714082	60714105	14	+	26627737	HCT116	viability after 18 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	1.1655940859551126	[277]	[321,202,389]	8	hSpCas9	negative selection	2188304
60720318	60720341	14	+	26627737	HCT116	viability after 18 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.5865736176782318	[739]	[82,230,408]	-5	hSpCas9	negative selection	2188305
60723439	60723462	14	-	26627737	HCT116	viability after 18 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	-1.3061614572222977	[368]	[56,81,76]	-8	hSpCas9	negative selection	2188306
60723456	60723479	14	+	26627737	HCT116	viability after 18 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-1.4747698406949088	[225]	[13,31,73]	-8	hSpCas9	negative selection	2188307
60723987	60724010	14	-	26627737	HCT116	viability after 18 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.2905086210406793	[43]	[31,23,21]	2	hSpCas9	negative selection	2188308
60723880	60723903	14	+	24336569	HL60	viability	CACCCTGGCGGCAGCGGTCGCGG	SIX4	ENSG00000100625	-0.36603166801233133	[242]	[398]	-3	hSpCas9	negative selection	2295233
60723965	60723988	14	-	24336569	HL60	viability	GAGGCGCACCGAGAAGTGGCGGG	SIX4	ENSG00000100625	1.222566789731909	[291]	[1441]	8	hSpCas9	negative selection	2295234
60723979	60724002	14	+	24336569	HL60	viability	GTGCGCCTCCTGCCCTTCCGAGG	SIX4	ENSG00000100625	0.2338536961376394	[699]	[1741]	2	hSpCas9	negative selection	2295235
60723984	60724007	14	-	24336569	HL60	viability	AAGCGCCTCGGAAGGGCAGGAGG	SIX4	ENSG00000100625	-0.2532304488953758	[97]	[173]	-2	hSpCas9	negative selection	2295236
60723991	60724014	14	-	24336569	HL60	viability	GGATGGAAAGCGCCTCGGAAGGG	SIX4	ENSG00000100625	-0.6989042248672268	[437]	[570]	-6	hSpCas9	negative selection	2295237
60723996	60724019	14	-	24336569	HL60	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	-0.16392626082086925	[836]	[1580]	-1	hSpCas9	negative selection	2295238
60724008	60724031	14	-	24336569	HL60	viability	CATCAAGCAAGAGAATGGGATGG	SIX4	ENSG00000100625	-0.9960251858642044	[1048]	[1112]	-7	hSpCas9	negative selection	2295239
60724013	60724036	14	-	24336569	HL60	viability	GCGGACATCAAGCAAGAGAATGG	SIX4	ENSG00000100625	0.027919358878365497	[145]	[314]	0	hSpCas9	negative selection	2295240
60724032	60724055	14	-	24336569	HL60	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.24530074878620423	[1071]	[2688]	2	hSpCas9	negative selection	2295241
60724037	60724060	14	+	24336569	HL60	viability	GCACTTGCGATCTGCCCGGTGGG	SIX4	ENSG00000100625	1.1288329956755367	[230]	[1068]	8	hSpCas9	negative selection	2295242
60723880	60723903	14	+	24336569	KBM7	viability	CACCCTGGCGGCAGCGGTCGCGG	SIX4	ENSG00000100625	0.5470542937013021	[201]	[804]	5	hSpCas9	negative selection	2362410
60723965	60723988	14	-	24336569	KBM7	viability	GAGGCGCACCGAGAAGTGGCGGG	SIX4	ENSG00000100625	-0.41706045616233167	[724]	[1480]	-3	hSpCas9	negative selection	2362411
60723979	60724002	14	+	24336569	KBM7	viability	GTGCGCCTCCTGCCCTTCCGAGG	SIX4	ENSG00000100625	-0.19719803606179231	[772]	[1838]	-2	hSpCas9	negative selection	2362412
60723984	60724007	14	-	24336569	KBM7	viability	AAGCGCCTCGGAAGGGCAGGAGG	SIX4	ENSG00000100625	-1.651112590634015	[75]	[65]	-8	hSpCas9	negative selection	2362413
60723991	60724014	14	-	24336569	KBM7	viability	GGATGGAAAGCGCCTCGGAAGGG	SIX4	ENSG00000100625	-0.004534384288659321	[490]	[1334]	0	hSpCas9	negative selection	2362414
60723996	60724019	14	-	24336569	KBM7	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	-0.6257827621027925	[567]	[1003]	-5	hSpCas9	negative selection	2362415
60724008	60724031	14	-	24336569	KBM7	viability	CATCAAGCAAGAGAATGGGATGG	SIX4	ENSG00000100625	0.45527729635174086	[763]	[2856]	4	hSpCas9	negative selection	2362416
60724013	60724036	14	-	24336569	KBM7	viability	GCGGACATCAAGCAAGAGAATGG	SIX4	ENSG00000100625	-0.20614101952188824	[257]	[609]	-2	hSpCas9	negative selection	2362417
60724032	60724055	14	-	24336569	KBM7	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.3093070917405838	[747]	[2527]	3	hSpCas9	negative selection	2362418
60724037	60724060	14	+	24336569	KBM7	viability	GCACTTGCGATCTGCCCGGTGGG	SIX4	ENSG00000100625	0.516148276279212	[291]	[1138]	5	hSpCas9	negative selection	2362419
60724203	60724226	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCAGATACAGCCGAAACCAGG	SIX4	ENSG00000100625	1.0458925246808262	[18,94]	[3,49]	4	dCas9-VP64	positive selection	2448437
60724255	60724278	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTCTAACAGCTATCTTAATGG	SIX4	ENSG00000100625	-2.2081625080599876	[60,269]	[4,9]	-9	dCas9-VP64	positive selection	2448438
60724224	60724247	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGCCGGGGGGAAACCTGATCGG	SIX4	ENSG00000100625	2.5163931307772853	[300,189]	[573,21]	8	dCas9-VP64	positive selection	2448439
60724203	60724226	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCAGATACAGCCGAAACCAGG	SIX4	ENSG00000100625	0.059354952964661534	[14,62]	[6,17]	0	dCas9-VP64	positive selection	2543692
60724255	60724278	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTCTAACAGCTATCTTAATGG	SIX4	ENSG00000100625	0.20228764069028687	[216,94]	[113,7]	1	dCas9-VP64	positive selection	2543693
60724224	60724247	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGCCGGGGGGAAACCTGATCGG	SIX4	ENSG00000100625	-0.5629440027665117	[140,128]	[36,21]	-5	dCas9-VP64	positive selection	2543694
60723880	60723903	14	+	27260157	DLD1	viability	CACCCTGGCGGCAGCGGTCGCGG	SIX4	ENSG00000100625	-0.229996714132675	[]	[]	-2	hSpCas9	negative selection	2574340
60723996	60724019	14	-	27260157	DLD1	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.509247654687867	[]	[]	8	hSpCas9	negative selection	2577350
60723720	60723743	14	-	27260157	DLD1	viability	CCACGTCGCCTGCGTGTGCGAGG	SIX4	ENSG00000100625	0.207473216688116	[]	[]	3	hSpCas9	negative selection	2580981
60723984	60724007	14	-	27260157	DLD1	viability	AAGCGCCTCGGAAGGGCAGGAGG	SIX4	ENSG00000100625	-0.601353183013244	[]	[]	-5	hSpCas9	negative selection	2586402
60723565	60723588	14	+	27260157	DLD1	viability	CTCGAGGATGCTGTAGAGCTCGG	SIX4	ENSG00000100625	0.262252790079374	[]	[]	4	hSpCas9	negative selection	2587467
60723724	60723747	14	+	27260157	DLD1	viability	GCACACGCAGGCGACGTGGTCGG	SIX4	ENSG00000100625	0.204422048146675	[]	[]	3	hSpCas9	negative selection	2587538
60724033	60724056	14	+	27260157	DLD1	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	-1.34008913534965	[]	[]	-8	hSpCas9	negative selection	2587645
60723823	60723846	14	+	27260157	DLD1	viability	TACCTGATCCGCCGCCGCTCCGG	SIX4	ENSG00000100625	-1.36400675861176	[]	[]	-8	hSpCas9	negative selection	2605926
60723965	60723988	14	-	27260157	DLD1	viability	GAGGCGCACCGAGAAGTGGCGGG	SIX4	ENSG00000100625	1.61320970844609	[]	[]	9	hSpCas9	negative selection	2612331
60724032	60724055	14	-	27260157	DLD1	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	-0.674126508785718	[]	[]	-5	hSpCas9	negative selection	2612920
60723643	60723666	14	+	27260157	DLD1	viability	GCCACGTAGCAGGTCGCTCTGGG	SIX4	ENSG00000100625	0.322653211217861	[]	[]	4	hSpCas9	negative selection	2613538
60724037	60724060	14	+	27260157	DLD1	viability	GCACTTGCGATCTGCCCGGTGGG	SIX4	ENSG00000100625	-0.450501348449336	[]	[]	-4	hSpCas9	negative selection	2617619
60723596	60723619	14	-	27260157	DLD1	viability	GCGCTCGTGGCCTTCCACCAGGG	SIX4	ENSG00000100625	0.0515301867705965	[]	[]	3	hSpCas9	negative selection	2619495
60724008	60724031	14	-	27260157	DLD1	viability	CATCAAGCAAGAGAATGGGATGG	SIX4	ENSG00000100625	0.541685018185034	[]	[]	8	hSpCas9	negative selection	2621098
60723796	60723819	14	-	27260157	DLD1	viability	TCCACTCGGAACTTCTGGGCAGG	SIX4	ENSG00000100625	-1.59723943246526	[]	[]	-8	hSpCas9	negative selection	2623832
60724013	60724036	14	-	27260157	DLD1	viability	GCGGACATCAAGCAAGAGAATGG	SIX4	ENSG00000100625	1.19575734654977	[]	[]	9	hSpCas9	negative selection	2642642
60723633	60723656	14	+	27260157	DLD1	viability	GGCTCTCGTTGCCACGTAGCAGG	SIX4	ENSG00000100625	-0.0374406546667317	[]	[]	0	hSpCas9	negative selection	2645815
60723962	60723985	14	-	27260157	DLD1	viability	GCGCACCGAGAAGTGGCGGGGGG	SIX4	ENSG00000100625	0.319026918025113	[]	[]	4	hSpCas9	negative selection	2645943
60723991	60724014	14	-	27260157	DLD1	viability	GGATGGAAAGCGCCTCGGAAGGG	SIX4	ENSG00000100625	1.1429586651162	[]	[]	9	hSpCas9	negative selection	2647637
60723880	60723903	14	+	27260157	HT1080	viability	CACCCTGGCGGCAGCGGTCGCGG	SIX4	ENSG00000100625	-0.770023822385428	[]	[]	-8	hSpCas9	negative selection	2650470
60723996	60724019	14	-	27260157	HT1080	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.151366448508799	[]	[]	1	hSpCas9	negative selection	2653480
60723720	60723743	14	-	27260157	HT1080	viability	CCACGTCGCCTGCGTGTGCGAGG	SIX4	ENSG00000100625	0.305710172904192	[]	[]	3	hSpCas9	negative selection	2657111
60723984	60724007	14	-	27260157	HT1080	viability	AAGCGCCTCGGAAGGGCAGGAGG	SIX4	ENSG00000100625	-0.783339613730428	[]	[]	-8	hSpCas9	negative selection	2662532
60723565	60723588	14	+	27260157	HT1080	viability	CTCGAGGATGCTGTAGAGCTCGG	SIX4	ENSG00000100625	0.738380838233962	[]	[]	6	hSpCas9	negative selection	2663597
60723724	60723747	14	+	27260157	HT1080	viability	GCACACGCAGGCGACGTGGTCGG	SIX4	ENSG00000100625	0.0916775085528758	[]	[]	1	hSpCas9	negative selection	2663668
60724033	60724056	14	+	27260157	HT1080	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	-1.07669960645451	[]	[]	-8	hSpCas9	negative selection	2663775
60723823	60723846	14	+	27260157	HT1080	viability	TACCTGATCCGCCGCCGCTCCGG	SIX4	ENSG00000100625	-0.398019384483438	[]	[]	-7	hSpCas9	negative selection	2682056
60723965	60723988	14	-	27260157	HT1080	viability	GAGGCGCACCGAGAAGTGGCGGG	SIX4	ENSG00000100625	1.10518247477956	[]	[]	8	hSpCas9	negative selection	2688461
60724032	60724055	14	-	27260157	HT1080	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.755591040000507	[]	[]	6	hSpCas9	negative selection	2689050
60723643	60723666	14	+	27260157	HT1080	viability	GCCACGTAGCAGGTCGCTCTGGG	SIX4	ENSG00000100625	0.268472139798523	[]	[]	2	hSpCas9	negative selection	2689668
60724037	60724060	14	+	27260157	HT1080	viability	GCACTTGCGATCTGCCCGGTGGG	SIX4	ENSG00000100625	-1.09829119411605	[]	[]	-8	hSpCas9	negative selection	2693749
60723596	60723619	14	-	27260157	HT1080	viability	GCGCTCGTGGCCTTCCACCAGGG	SIX4	ENSG00000100625	0.0903723695517759	[]	[]	1	hSpCas9	negative selection	2695625
60724008	60724031	14	-	27260157	HT1080	viability	CATCAAGCAAGAGAATGGGATGG	SIX4	ENSG00000100625	1.22160135659003	[]	[]	8	hSpCas9	negative selection	2697228
60723796	60723819	14	-	27260157	HT1080	viability	TCCACTCGGAACTTCTGGGCAGG	SIX4	ENSG00000100625	-1.95119964904568	[]	[]	-9	hSpCas9	negative selection	2699962
60724013	60724036	14	-	27260157	HT1080	viability	GCGGACATCAAGCAAGAGAATGG	SIX4	ENSG00000100625	0.618845095827547	[]	[]	5	hSpCas9	negative selection	2718772
60723633	60723656	14	+	27260157	HT1080	viability	GGCTCTCGTTGCCACGTAGCAGG	SIX4	ENSG00000100625	-0.616138592411397	[]	[]	-8	hSpCas9	negative selection	2721945
60723962	60723985	14	-	27260157	HT1080	viability	GCGCACCGAGAAGTGGCGGGGGG	SIX4	ENSG00000100625	-0.154107549821341	[]	[]	0	hSpCas9	negative selection	2722073
60723991	60724014	14	-	27260157	HT1080	viability	GGATGGAAAGCGCCTCGGAAGGG	SIX4	ENSG00000100625	0.529134125976565	[]	[]	4	hSpCas9	negative selection	2723767
60723880	60723903	14	+	27260157	MKN45	viability	CACCCTGGCGGCAGCGGTCGCGG	SIX4	ENSG00000100625	-1.05739629232176	[]	[]	-8	hSpCas9	negative selection	2726600
60723996	60724019	14	-	27260157	MKN45	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	-0.0560678257343478	[]	[]	0	hSpCas9	negative selection	2729610
60723720	60723743	14	-	27260157	MKN45	viability	CCACGTCGCCTGCGTGTGCGAGG	SIX4	ENSG00000100625	0.654422847703357	[]	[]	7	hSpCas9	negative selection	2733241
60723984	60724007	14	-	27260157	MKN45	viability	AAGCGCCTCGGAAGGGCAGGAGG	SIX4	ENSG00000100625	-1.04085514777377	[]	[]	-8	hSpCas9	negative selection	2738662
60723565	60723588	14	+	27260157	MKN45	viability	CTCGAGGATGCTGTAGAGCTCGG	SIX4	ENSG00000100625	1.11053867484047	[]	[]	8	hSpCas9	negative selection	2739727
60723724	60723747	14	+	27260157	MKN45	viability	GCACACGCAGGCGACGTGGTCGG	SIX4	ENSG00000100625	0.609313260228815	[]	[]	7	hSpCas9	negative selection	2739798
60724033	60724056	14	+	27260157	MKN45	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	-2.51593108671428	[]	[]	-9	hSpCas9	negative selection	2739905
60723823	60723846	14	+	27260157	MKN45	viability	TACCTGATCCGCCGCCGCTCCGG	SIX4	ENSG00000100625	-1.14089899748332	[]	[]	-8	hSpCas9	negative selection	2758186
60723965	60723988	14	-	27260157	MKN45	viability	GAGGCGCACCGAGAAGTGGCGGG	SIX4	ENSG00000100625	1.27622222591208	[]	[]	9	hSpCas9	negative selection	2764591
60724032	60724055	14	-	27260157	MKN45	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.0130342953839393	[]	[]	0	hSpCas9	negative selection	2765180
60723643	60723666	14	+	27260157	MKN45	viability	GCCACGTAGCAGGTCGCTCTGGG	SIX4	ENSG00000100625	0.507798483301308	[]	[]	6	hSpCas9	negative selection	2765798
60724037	60724060	14	+	27260157	MKN45	viability	GCACTTGCGATCTGCCCGGTGGG	SIX4	ENSG00000100625	-0.732283249207149	[]	[]	-7	hSpCas9	negative selection	2769879
60723596	60723619	14	-	27260157	MKN45	viability	GCGCTCGTGGCCTTCCACCAGGG	SIX4	ENSG00000100625	1.22431146971483	[]	[]	9	hSpCas9	negative selection	2771755
60724008	60724031	14	-	27260157	MKN45	viability	CATCAAGCAAGAGAATGGGATGG	SIX4	ENSG00000100625	1.58225549503103	[]	[]	9	hSpCas9	negative selection	2773358
60723796	60723819	14	-	27260157	MKN45	viability	TCCACTCGGAACTTCTGGGCAGG	SIX4	ENSG00000100625	-0.446235392402382	[]	[]	-6	hSpCas9	negative selection	2776092
60724013	60724036	14	-	27260157	MKN45	viability	GCGGACATCAAGCAAGAGAATGG	SIX4	ENSG00000100625	0.946659818715811	[]	[]	8	hSpCas9	negative selection	2794902
60723633	60723656	14	+	27260157	MKN45	viability	GGCTCTCGTTGCCACGTAGCAGG	SIX4	ENSG00000100625	0.176124873187743	[]	[]	5	hSpCas9	negative selection	2798075
60723962	60723985	14	-	27260157	MKN45	viability	GCGCACCGAGAAGTGGCGGGGGG	SIX4	ENSG00000100625	-0.340087306438357	[]	[]	-1	hSpCas9	negative selection	2798203
60723991	60724014	14	-	27260157	MKN45	viability	GGATGGAAAGCGCCTCGGAAGGG	SIX4	ENSG00000100625	1.00813210565014	[]	[]	8	hSpCas9	negative selection	2799897
60723880	60723903	14	+	27260157	RKO	viability	CACCCTGGCGGCAGCGGTCGCGG	SIX4	ENSG00000100625	-0.0574838613759252	[]	[]	0	hSpCas9	negative selection	2802730
60723996	60724019	14	-	27260157	RKO	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	-0.205933917954882	[]	[]	-1	hSpCas9	negative selection	2805740
60723720	60723743	14	-	27260157	RKO	viability	CCACGTCGCCTGCGTGTGCGAGG	SIX4	ENSG00000100625	0.87123303629804	[]	[]	8	hSpCas9	negative selection	2809371
60723984	60724007	14	-	27260157	RKO	viability	AAGCGCCTCGGAAGGGCAGGAGG	SIX4	ENSG00000100625	-0.948385802044027	[]	[]	-8	hSpCas9	negative selection	2814792
60723565	60723588	14	+	27260157	RKO	viability	CTCGAGGATGCTGTAGAGCTCGG	SIX4	ENSG00000100625	0.919356832233476	[]	[]	8	hSpCas9	negative selection	2815857
60723724	60723747	14	+	27260157	RKO	viability	GCACACGCAGGCGACGTGGTCGG	SIX4	ENSG00000100625	0.581786556599016	[]	[]	3	hSpCas9	negative selection	2815928
60724033	60724056	14	+	27260157	RKO	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	-1.88426435212712	[]	[]	-9	hSpCas9	negative selection	2816035
60723823	60723846	14	+	27260157	RKO	viability	TACCTGATCCGCCGCCGCTCCGG	SIX4	ENSG00000100625	-0.171525538087023	[]	[]	-1	hSpCas9	negative selection	2834316
60723965	60723988	14	-	27260157	RKO	viability	GAGGCGCACCGAGAAGTGGCGGG	SIX4	ENSG00000100625	1.06776138252242	[]	[]	9	hSpCas9	negative selection	2840721
60724032	60724055	14	-	27260157	RKO	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	-0.126593948274484	[]	[]	0	hSpCas9	negative selection	2841310
60723643	60723666	14	+	27260157	RKO	viability	GCCACGTAGCAGGTCGCTCTGGG	SIX4	ENSG00000100625	-0.0247612739582598	[]	[]	0	hSpCas9	negative selection	2841928
60724037	60724060	14	+	27260157	RKO	viability	GCACTTGCGATCTGCCCGGTGGG	SIX4	ENSG00000100625	-0.0957103073813632	[]	[]	0	hSpCas9	negative selection	2846009
60723596	60723619	14	-	27260157	RKO	viability	GCGCTCGTGGCCTTCCACCAGGG	SIX4	ENSG00000100625	-0.0454021145121665	[]	[]	0	hSpCas9	negative selection	2847885
60724008	60724031	14	-	27260157	RKO	viability	CATCAAGCAAGAGAATGGGATGG	SIX4	ENSG00000100625	1.0800297569091	[]	[]	9	hSpCas9	negative selection	2849488
60723796	60723819	14	-	27260157	RKO	viability	TCCACTCGGAACTTCTGGGCAGG	SIX4	ENSG00000100625	-0.623035813062451	[]	[]	-7	hSpCas9	negative selection	2852222
60724013	60724036	14	-	27260157	RKO	viability	GCGGACATCAAGCAAGAGAATGG	SIX4	ENSG00000100625	0.846283358985667	[]	[]	8	hSpCas9	negative selection	2871032
60723633	60723656	14	+	27260157	RKO	viability	GGCTCTCGTTGCCACGTAGCAGG	SIX4	ENSG00000100625	0.927963802160463	[]	[]	8	hSpCas9	negative selection	2874205
60723962	60723985	14	-	27260157	RKO	viability	GCGCACCGAGAAGTGGCGGGGGG	SIX4	ENSG00000100625	-0.432035344900229	[]	[]	-6	hSpCas9	negative selection	2874333
60723991	60724014	14	-	27260157	RKO	viability	GGATGGAAAGCGCCTCGGAAGGG	SIX4	ENSG00000100625	0.185043677741198	[]	[]	1	hSpCas9	negative selection	2876027
60723880	60723903	14	+	27260157	SF268	viability	CACCCTGGCGGCAGCGGTCGCGG	SIX4	ENSG00000100625	-0.979769057222457	[]	[]	-7	hSpCas9	negative selection	2878860
60723996	60724019	14	-	27260157	SF268	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.30100335773055	[]	[]	4	hSpCas9	negative selection	2881870
60723720	60723743	14	-	27260157	SF268	viability	CCACGTCGCCTGCGTGTGCGAGG	SIX4	ENSG00000100625	0.199679197022014	[]	[]	3	hSpCas9	negative selection	2885501
60723984	60724007	14	-	27260157	SF268	viability	AAGCGCCTCGGAAGGGCAGGAGG	SIX4	ENSG00000100625	-0.844688393109347	[]	[]	-6	hSpCas9	negative selection	2890922
60723565	60723588	14	+	27260157	SF268	viability	CTCGAGGATGCTGTAGAGCTCGG	SIX4	ENSG00000100625	1.16811920282919	[]	[]	9	hSpCas9	negative selection	2891987
60723724	60723747	14	+	27260157	SF268	viability	GCACACGCAGGCGACGTGGTCGG	SIX4	ENSG00000100625	-0.241538034399041	[]	[]	-2	hSpCas9	negative selection	2892058
60724033	60724056	14	+	27260157	SF268	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	-1.92577305995286	[]	[]	-8	hSpCas9	negative selection	2892165
60723823	60723846	14	+	27260157	SF268	viability	TACCTGATCCGCCGCCGCTCCGG	SIX4	ENSG00000100625	-0.431616422997123	[]	[]	-3	hSpCas9	negative selection	2910446
60723965	60723988	14	-	27260157	SF268	viability	GAGGCGCACCGAGAAGTGGCGGG	SIX4	ENSG00000100625	1.13038799363405	[]	[]	9	hSpCas9	negative selection	2916851
60724032	60724055	14	-	27260157	SF268	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	-0.10359310206241	[]	[]	-1	hSpCas9	negative selection	2917440
60723643	60723666	14	+	27260157	SF268	viability	GCCACGTAGCAGGTCGCTCTGGG	SIX4	ENSG00000100625	0.0108971050981887	[]	[]	0	hSpCas9	negative selection	2918058
60724037	60724060	14	+	27260157	SF268	viability	GCACTTGCGATCTGCCCGGTGGG	SIX4	ENSG00000100625	0.073321168176415	[]	[]	0	hSpCas9	negative selection	2922139
60723596	60723619	14	-	27260157	SF268	viability	GCGCTCGTGGCCTTCCACCAGGG	SIX4	ENSG00000100625	0.0518286208182531	[]	[]	0	hSpCas9	negative selection	2924015
60724008	60724031	14	-	27260157	SF268	viability	CATCAAGCAAGAGAATGGGATGG	SIX4	ENSG00000100625	1.1091297793998	[]	[]	9	hSpCas9	negative selection	2925618
60723796	60723819	14	-	27260157	SF268	viability	TCCACTCGGAACTTCTGGGCAGG	SIX4	ENSG00000100625	-0.273107869974462	[]	[]	-2	hSpCas9	negative selection	2928352
60724013	60724036	14	-	27260157	SF268	viability	GCGGACATCAAGCAAGAGAATGG	SIX4	ENSG00000100625	0.783522759319802	[]	[]	8	hSpCas9	negative selection	2947162
60723633	60723656	14	+	27260157	SF268	viability	GGCTCTCGTTGCCACGTAGCAGG	SIX4	ENSG00000100625	0.163005520163769	[]	[]	0	hSpCas9	negative selection	2950335
60723962	60723985	14	-	27260157	SF268	viability	GCGCACCGAGAAGTGGCGGGGGG	SIX4	ENSG00000100625	0.236454773788986	[]	[]	3	hSpCas9	negative selection	2950463
60723991	60724014	14	-	27260157	SF268	viability	GGATGGAAAGCGCCTCGGAAGGG	SIX4	ENSG00000100625	0.158908557488997	[]	[]	0	hSpCas9	negative selection	2952157
60723796	60723819	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCTGCCCAGAAGTTCCGAGTGG	SIX4	ENSG00000100625	0.3068043320623184	[4,3]	[5,3]	6	hSpCas9	positive selection	3020426
60723810	60723833	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATCAGGTACAACTCCACTCGG	SIX4	ENSG00000100625	0.035609149615940305	[4,4]	[3,3]	0	hSpCas9	positive selection	3020427
60723495	60723518	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	-0.4449682513859737	[3,3]	[2,1]	-6	hSpCas9	positive selection	3020428
60723453	60723476	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TACTTGTCTACGGCTCCCAGCGG	SIX4	ENSG00000100625	0.481357892877759	[3,2]	[3,3]	8	hSpCas9	positive selection	3020429
60723796	60723819	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCTGCCCAGAAGTTCCGAGTGG	SIX4	ENSG00000100625	0.04805981882368032	[4,4]	[4,1]	0	hSpCas9	positive selection	3088284
60723810	60723833	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATCAGGTACAACTCCACTCGG	SIX4	ENSG00000100625	0.2569020643770206	[4,4]	[5,2]	4	hSpCas9	positive selection	3088285
60723495	60723518	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.5194120032070516	[3,3]	[5,2]	8	hSpCas9	positive selection	3088286
60723453	60723476	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TACTTGTCTACGGCTCCCAGCGG	SIX4	ENSG00000100625	0.24504364770307818	[3,3]	[3,1]	4	hSpCas9	positive selection	3088287
60723313	60723336		-	24336571	A375	resistance to PLX after 7 days	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.14723315568925865	[12,5]	[8,7]	-5	hSpCas9	positive selection	3144383
60720070	60720093		+	24336571	A375	resistance to PLX after 7 days	AGACCCCAGTATGTCAGTCATGG	SIX4	ENSG00000100625	-0.15145466854339595	[8,10]	[8,8]	-5	hSpCas9	positive selection	3144384
60723357	60723380		-	24336571	A375	resistance to PLX after 7 days	GAAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	-0.20321100055436092	[5,6]	[4,5]	-6	hSpCas9	positive selection	3144385
60720051	60720074		-	24336571	A375	resistance to PLX after 7 days	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.4599359451376919	[11,9]	[7,7]	-9	hSpCas9	positive selection	3144386
60723313	60723336		-	24336571	A375	resistance to PLX after 14 days	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.13009896740089555	[11,6]	[2,3]	-1	hSpCas9	positive selection	3202176
60720070	60720093		+	24336571	A375	resistance to PLX after 14 days	AGACCCCAGTATGTCAGTCATGG	SIX4	ENSG00000100625	0.3136435653490147	[11,9]	[4,7]	3	hSpCas9	positive selection	3202177
60723357	60723380		-	24336571	A375	resistance to PLX after 14 days	GAAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	0.4161328041779023	[3,6]	[3,2]	4	hSpCas9	positive selection	3202178
60720051	60720074		-	24336571	A375	resistance to PLX after 14 days	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.41856639879304164	[9,9]	[3,1]	-5	hSpCas9	positive selection	3202179
60723313	60723336		-	24336571	A375	viability after 7 days	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.05524538409721724	[9]	[12,5]	0	hSpCas9	negative selection	3259969
60720070	60720093		+	24336571	A375	viability after 7 days	AGACCCCAGTATGTCAGTCATGG	SIX4	ENSG00000100625	-0.07567704771243025	[10]	[8,10]	-1	hSpCas9	negative selection	3259970
60723357	60723380		-	24336571	A375	viability after 7 days	GAAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	0.11486109509474718	[5]	[5,6]	1	hSpCas9	negative selection	3259971
60720051	60720074		-	24336571	A375	viability after 7 days	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.13302885411729434	[12]	[11,9]	-2	hSpCas9	negative selection	3259972
60723313	60723336		-	24336571	A375	viability after 14 days	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.05858659767109542	[9]	[11,6]	0	hSpCas9	negative selection	3317762
60720070	60720093		+	24336571	A375	viability after 14 days	AGACCCCAGTATGTCAGTCATGG	SIX4	ENSG00000100625	0.08955118546438226	[10]	[11,9]	1	hSpCas9	negative selection	3317763
60723357	60723380		-	24336571	A375	viability after 14 days	GAAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	-0.024310327858857672	[5]	[3,6]	0	hSpCas9	negative selection	3317764
60720051	60720074		-	24336571	A375	viability after 14 days	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.28115416462969484	[12]	[9,9]	-3	hSpCas9	negative selection	3317765
60724033	60724056	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	-2.519106820998898	[876,876]	[0,0]	-9	hSpCas9	positive selection	3392538
60719827	60719850	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.23495839841738073	[129,129]	[0,0]	1	hSpCas9	positive selection	3392539
60720051	60720074	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	0.24609895602258094	[128,128]	[0,0]	1	hSpCas9	positive selection	3392540
60723795	60723818	14	+	26780180	HT29	viability (Avana library 4 designs)	GCCTGCCCAGAAGTTCCGAGTGG	SIX4	ENSG00000100625	0.799825011384245	[]	[]	3	hSpCas9	negative selection	3458938
60723810	60723833	14	-	26780180	HT29	viability (Avana library 4 designs)	GGATCAGGTACAACTCCACTCGG	SIX4	ENSG00000100625	-0.443897618600725	[]	[]	-6	hSpCas9	negative selection	3458939
60723495	60723518	14	-	26780180	HT29	viability (Avana library 4 designs)	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.245061177574255	[]	[]	0	hSpCas9	negative selection	3458940
60723452	60723475	14	+	26780180	HT29	viability (Avana library 4 designs)	TACTTGTCTACGGCTCCCAGCGG	SIX4	ENSG00000100625	1.1469948269541	[]	[]	4	hSpCas9	negative selection	3458941
60723495	60723518	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	3.63381177773127	[]	[]	6	hSpCas9	negative selection	3558621
60723795	60723818	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTGCCCAGAAGTTCCGAGTGG	SIX4	ENSG00000100625	4.34385456167591	[]	[]	7	hSpCas9	negative selection	3558622
60723452	60723475	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	TACTTGTCTACGGCTCCCAGCGG	SIX4	ENSG00000100625	1.93644293496883	[]	[]	3	hSpCas9	negative selection	3558623
60723810	60723833	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATCAGGTACAACTCCACTCGG	SIX4	ENSG00000100625	-2.00750223885189	[]	[]	-2	hSpCas9	negative selection	3558624
60720401	60720424	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGAAGATGAATCCAGCAAGGG	SIX4	ENSG00000100625	1.56305723451352	[]	[]	2	hSpCas9	negative selection	3558625
60723250	60723273	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	0.312588535959209	[]	[]	0	hSpCas9	negative selection	3558626
60723495	60723518	14	-	26780180	A375	viability (Avana lentiGuide)	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	1.49919998400401	[]	[]	1	hSpCas9	negative selection	3667280
60723795	60723818	14	+	26780180	A375	viability (Avana lentiGuide)	GCCTGCCCAGAAGTTCCGAGTGG	SIX4	ENSG00000100625	-4.31266169610793	[]	[]	-7	hSpCas9	negative selection	3667281
60723452	60723475	14	+	26780180	A375	viability (Avana lentiGuide)	TACTTGTCTACGGCTCCCAGCGG	SIX4	ENSG00000100625	1.59339149039023	[]	[]	1	hSpCas9	negative selection	3667282
60723810	60723833	14	-	26780180	A375	viability (Avana lentiGuide)	GGATCAGGTACAACTCCACTCGG	SIX4	ENSG00000100625	-2.25197741411365	[]	[]	-4	hSpCas9	negative selection	3667283
60720401	60720424	14	-	26780180	A375	viability (Avana lentiGuide)	ACTGAAGATGAATCCAGCAAGGG	SIX4	ENSG00000100625	-2.42817706127993	[]	[]	-4	hSpCas9	negative selection	3667284
60723250	60723273	14	-	26780180	A375	viability (Avana lentiGuide)	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	2.69757859478535	[]	[]	3	hSpCas9	negative selection	3667285
60723495	60723518	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	-0.04858955118045992	[4]	[5,3]	-1	hSpCas9	positive selection	3775887
60723795	60723818	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTGCCCAGAAGTTCCGAGTGG	SIX4	ENSG00000100625	0.3270859852738082	[5]	[5,6]	8	hSpCas9	positive selection	3775888
60723452	60723475	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TACTTGTCTACGGCTCCCAGCGG	SIX4	ENSG00000100625	-0.05826241624811964	[5]	[5,4]	-1	hSpCas9	positive selection	3775889
60723810	60723833	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATCAGGTACAACTCCACTCGG	SIX4	ENSG00000100625	0.14866787026362074	[5]	[5,6]	4	hSpCas9	positive selection	3775890
60720401	60720424	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGAAGATGAATCCAGCAAGGG	SIX4	ENSG00000100625	-0.057713479371425624	[6]	[5,5]	-1	hSpCas9	positive selection	3775891
60723250	60723273	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	-0.06661112812052838	[5]	[4,4]	-1	hSpCas9	positive selection	3775892
60723495	60723518	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	-0.3081542926078829	[5]	[3,3]	-4	hSpCas9	positive selection	3884494
60723795	60723818	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTGCCCAGAAGTTCCGAGTGG	SIX4	ENSG00000100625	0.10511002093447461	[6]	[5,5]	2	hSpCas9	positive selection	3884495
60723452	60723475	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TACTTGTCTACGGCTCCCAGCGG	SIX4	ENSG00000100625	-0.3008223541241909	[5]	[1,5]	-4	hSpCas9	positive selection	3884496
60723810	60723833	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATCAGGTACAACTCCACTCGG	SIX4	ENSG00000100625	0.36680637294140495	[5]	[6,6]	9	hSpCas9	positive selection	3884497
60720401	60720424	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGAAGATGAATCCAGCAAGGG	SIX4	ENSG00000100625	0.3461288446653842	[5]	[6,5]	8	hSpCas9	positive selection	3884498
60723250	60723273	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	0.06152779373599809	[6]	[4,6]	1	hSpCas9	positive selection	3884499
60714082	60714105	14	+	26780180	A375	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	1.08206460694618	[]	[]	5	hSpCas9	negative selection	3994550
60713842	60713865	14	+	26780180	A375	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.901920345803459	[]	[]	4	hSpCas9	negative selection	3994551
60723313	60723336	14	-	26780180	A375	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.760913560306441	[]	[]	3	hSpCas9	negative selection	3994552
60724033	60724056	14	+	26780180	A375	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	1.41816361567834	[]	[]	7	hSpCas9	negative selection	3994553
60719827	60719850	14	+	26780180	A375	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.930499556875494	[]	[]	4	hSpCas9	negative selection	3994554
60720051	60720074	14	-	26780180	A375	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	1.01969363983605	[]	[]	5	hSpCas9	negative selection	3994555
60714082	60714105	14	+	26780180	HT29	viability (GeCKOv2 library)	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	1.34502677763272	[]	[]	6	hSpCas9	negative selection	4102516
60713842	60713865	14	+	26780180	HT29	viability (GeCKOv2 library)	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.13309102284783	[]	[]	0	hSpCas9	negative selection	4102517
60723313	60723336	14	-	26780180	HT29	viability (GeCKOv2 library)	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	1.00626362332534	[]	[]	4	hSpCas9	negative selection	4102518
60724033	60724056	14	+	26780180	HT29	viability (GeCKOv2 library)	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	2.08801073047853	[]	[]	9	hSpCas9	negative selection	4102519
60719827	60719850	14	+	26780180	HT29	viability (GeCKOv2 library)	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.704807986070863	[]	[]	2	hSpCas9	negative selection	4102520
60720051	60720074	14	-	26780180	HT29	viability (GeCKOv2 library)	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	1.896477957932	[]	[]	9	hSpCas9	negative selection	4102521
60723313	60723336	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.22813448601617073	[3]	[1,1]	-5	hSpCas9	positive selection	4170335
60720070	60720093	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACCCCAGTATGTCAGTCATGG	SIX4	ENSG00000100625	0.3935115190712333	[3]	[3,2]	8	hSpCas9	positive selection	4170336
60723357	60723380	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	-0.14824721444931013	[3]	[1,1]	-3	hSpCas9	positive selection	4170337
60720051	60720074	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.4108703381241082	[3]	[1,1]	-8	hSpCas9	positive selection	4170338
60723313	60723336	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.7130327536148646	[4]	[2,2,0,3]	4	hSpCas9	positive selection	4234357
60720070	60720093	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACCCCAGTATGTCAGTCATGG	SIX4	ENSG00000100625	1.3549539731505924	[3]	[4,4,3,4]	9	hSpCas9	positive selection	4234358
60723357	60723380	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	-0.41035505303637854	[2]	[1,0,0,0]	-6	hSpCas9	positive selection	4234359
60720051	60720074	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.15363860325329792	[3]	[0,3,0,0]	-2	hSpCas9	positive selection	4234360
60714082	60714105	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.13662992755744646	[2]	[3,1]	2	hSpCas9	positive selection	4297882
60713842	60713865	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.24731394251292493	[2]	[3,1]	5	hSpCas9	positive selection	4297883
60723313	60723336	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.29699911008431035	[1]	[1,0]	-6	hSpCas9	positive selection	4297884
60724033	60724056	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	-0.2790585625296732	[4]	[3,2]	-5	hSpCas9	positive selection	4362136
60719827	60719850	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.07484853675846398	[2]	[2,0]	1	hSpCas9	positive selection	4362137
60720051	60720074	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.3209907396041676	[2]	[2,0]	-6	hSpCas9	positive selection	4362138
60723212	60723234	14	+	27760321	OCIAML3	viability	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.4122084833583858	[784,780]	[852,770]	5	hSpCas9	negative selection	4439147
60723357	60723379	14	-	27760321	OCIAML3	viability	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	0.023662121337224562	[262,254]	[191,224]	0	hSpCas9	negative selection	4439148
60723448	60723470	14	-	27760321	OCIAML3	viability	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	-0.5391875580441146	[276,219]	[138,124]	-5	hSpCas9	negative selection	4439149
60723495	60723517	14	-	27760321	OCIAML3	viability	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	-0.5860089402879886	[352,265]	[165,151]	-5	hSpCas9	negative selection	4439150
60723644	60723666	14	-	27760321	OCIAML3	viability	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.049187169660501295	[757,638]	[484,664]	0	hSpCas9	negative selection	4439151
60723212	60723234	14	+	27760321	OCIAML2	viability	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.5902882833368001	[784,780]	[893,1038]	7	hSpCas9	negative selection	4522610
60723357	60723379	14	-	27760321	OCIAML2	viability	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	0.461459614186554	[262,254]	[235,358]	6	hSpCas9	negative selection	4522611
60723448	60723470	14	-	27760321	OCIAML2	viability	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	-0.4911540641907446	[276,219]	[120,169]	-5	hSpCas9	negative selection	4522612
60723495	60723517	14	-	27760321	OCIAML2	viability	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.16187934699081719	[352,265]	[203,374]	2	hSpCas9	negative selection	4522613
60723644	60723666	14	-	27760321	OCIAML2	viability	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.28636680022676775	[757,638]	[623,768]	4	hSpCas9	negative selection	4522614
60723212	60723234	14	+	27760321	MV411	viability	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.25378262308012045	[784,780]	[344,1027]	1	hSpCas9	negative selection	4606073
60723357	60723379	14	-	27760321	MV411	viability	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	1.504771938148332	[262,254]	[242,850]	9	hSpCas9	negative selection	4606074
60723448	60723470	14	-	27760321	MV411	viability	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	0.2427641173991556	[276,219]	[249,106]	1	hSpCas9	negative selection	4606075
60723495	60723517	14	-	27760321	MV411	viability	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.8152250295199948	[352,265]	[365,341]	6	hSpCas9	negative selection	4606076
60723644	60723666	14	-	27760321	MV411	viability	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.5344313480652167	[757,638]	[348,1139]	4	hSpCas9	negative selection	4606077
60723212	60723234	14	+	27760321	HL60	viability	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.022267087220379067	[784,780]	[520,789]	0	hSpCas9	negative selection	4689536
60723357	60723379	14	-	27760321	HL60	viability	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	0.6963219892279547	[262,254]	[343,342]	7	hSpCas9	negative selection	4689537
60723448	60723470	14	-	27760321	HL60	viability	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	0.23831952201508588	[276,219]	[220,255]	3	hSpCas9	negative selection	4689538
60723495	60723517	14	-	27760321	HL60	viability	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	-0.02727101535076004	[352,265]	[263,226]	0	hSpCas9	negative selection	4689539
60723644	60723666	14	-	27760321	HL60	viability	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.4939416202070823	[757,638]	[686,920]	6	hSpCas9	negative selection	4689540
60723212	60723234	14	+	27760321	HT1080	viability	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.23789824518242253	[780,609]	[310,343]	1	hSpCas9	negative selection	4772999
60723357	60723379	14	-	27760321	HT1080	viability	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	1.7617988206024413	[254,198]	[404,198]	8	hSpCas9	negative selection	4773000
60723448	60723470	14	-	27760321	HT1080	viability	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	-0.19279981173355287	[219,171]	[53,83]	-1	hSpCas9	negative selection	4773001
60723495	60723517	14	-	27760321	HT1080	viability	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	1.4413949442017606	[265,207]	[191,326]	7	hSpCas9	negative selection	4773002
60723644	60723666	14	-	27760321	HT1080	viability	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	3.6200400211833137	[638,498]	[3168,2368]	9	hSpCas9	negative selection	4773003
60723212	60723234	14	+	27760321	HT29	viability after 7 days	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	-0.12241556990973368	[780,609]	[1022,772,699]	-2	hSpCas9	negative selection	4856462
60723357	60723379	14	-	27760321	HT29	viability after 7 days	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	-0.32219903750335765	[254,198]	[227,262,208]	-4	hSpCas9	negative selection	4856463
60723448	60723470	14	-	27760321	HT29	viability after 7 days	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	-0.12069466285074593	[219,171]	[308,162,233]	-2	hSpCas9	negative selection	4856464
60723495	60723517	14	-	27760321	HT29	viability after 7 days	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.32225978353707596	[265,207]	[341,605,194]	5	hSpCas9	negative selection	4856465
60723644	60723666	14	-	27760321	HT29	viability after 7 days	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.6820392153833573	[638,498]	[1526,1091,957]	9	hSpCas9	negative selection	4856466
60723212	60723234	14	+	27760321	HT29	viability after 25 days	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.3623270314380158	[780,609]	[1053,751,1282]	4	hSpCas9	negative selection	4939925
60723357	60723379	14	-	27760321	HT29	viability after 25 days	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	0.1191591172748836	[254,198]	[264,168,426]	1	hSpCas9	negative selection	4939926
60723448	60723470	14	-	27760321	HT29	viability after 25 days	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	0.235947881965609	[219,171]	[365,254,151]	2	hSpCas9	negative selection	4939927
60723495	60723517	14	-	27760321	HT29	viability after 25 days	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.11968054416408641	[265,207]	[362,204,311]	1	hSpCas9	negative selection	4939928
60723644	60723666	14	-	27760321	HT29	viability after 25 days	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.9323839685367646	[638,498]	[1244,1225,1250]	9	hSpCas9	negative selection	4939929
60723212	60723234	14	+	27760321	HT29	viability after 22 days	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.31811888323540294	[780,609]	[696,952,1368]	3	hSpCas9	negative selection	5023388
60723357	60723379	14	-	27760321	HT29	viability after 22 days	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	-0.1233586387228659	[254,198]	[239,216,265]	-1	hSpCas9	negative selection	5023389
60723448	60723470	14	-	27760321	HT29	viability after 22 days	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	0.114731202361405	[219,171]	[339,203,188]	1	hSpCas9	negative selection	5023390
60723495	60723517	14	-	27760321	HT29	viability after 22 days	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	-0.34526250417620674	[265,207]	[210,241,193]	-3	hSpCas9	negative selection	5023391
60723644	60723666	14	-	27760321	HT29	viability after 22 days	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.9116256241790183	[638,498]	[1302,1018,1389]	9	hSpCas9	negative selection	5023392
60723212	60723234	14	+	27760321	HT29	viability after 19 days	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.05286552043254722	[780,609]	[839,1227,423]	0	hSpCas9	negative selection	5106851
60723357	60723379	14	-	27760321	HT29	viability after 19 days	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	-0.06085149823543734	[254,198]	[338,410,14]	0	hSpCas9	negative selection	5106852
60723448	60723470	14	-	27760321	HT29	viability after 19 days	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	-0.3932853422093313	[219,171]	[405,77,56]	-4	hSpCas9	negative selection	5106853
60723495	60723517	14	-	27760321	HT29	viability after 19 days	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.29963403396189464	[265,207]	[406,309,292]	3	hSpCas9	negative selection	5106854
60723644	60723666	14	-	27760321	HT29	viability after 19 days	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.9004296478294397	[638,498]	[1441,1111,1116]	8	hSpCas9	negative selection	5106855
60723212	60723234	14	+	27760321	HT29	viability after 16 days	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.2576451223583749	[780,609]	[771,885,1118]	3	hSpCas9	negative selection	5190314
60723357	60723379	14	-	27760321	HT29	viability after 16 days	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	-0.30589490146428533	[254,198]	[175,186,250]	-3	hSpCas9	negative selection	5190315
60723448	60723470	14	-	27760321	HT29	viability after 16 days	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	-1.067975846212296	[219,171]	[229,52,43]	-7	hSpCas9	negative selection	5190316
60723495	60723517	14	-	27760321	HT29	viability after 16 days	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.21251542217402447	[265,207]	[267,462,182]	2	hSpCas9	negative selection	5190317
60723644	60723666	14	-	27760321	HT29	viability after 16 days	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.5492027893608386	[638,498]	[998,773,1031]	6	hSpCas9	negative selection	5190318
60723212	60723234	14	+	27760321	HT29	viability after 13 days	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.037991801704064576	[780,609]	[698,967,818]	0	hSpCas9	negative selection	5273777
60723357	60723379	14	-	27760321	HT29	viability after 13 days	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	-0.2405672322408825	[254,198]	[175,273,218]	-3	hSpCas9	negative selection	5273778
60723448	60723470	14	-	27760321	HT29	viability after 13 days	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	-0.4291791413083351	[219,171]	[147,143,211]	-5	hSpCas9	negative selection	5273779
60723495	60723517	14	-	27760321	HT29	viability after 13 days	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.013334401388492734	[265,207]	[325,374,139]	0	hSpCas9	negative selection	5273780
60723644	60723666	14	-	27760321	HT29	viability after 13 days	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.889714996589264	[638,498]	[1044,1427,1197]	9	hSpCas9	negative selection	5273781
60723212	60723234	14	+	27760321	HT29	viability after 10 days	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.21297001299645446	[780,609]	[892,1207,925]	3	hSpCas9	negative selection	5357240
60723357	60723379	14	-	27760321	HT29	viability after 10 days	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	0.04295204944131903	[254,198]	[219,305,348]	0	hSpCas9	negative selection	5357241
60723448	60723470	14	-	27760321	HT29	viability after 10 days	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	-0.18990449455293013	[219,171]	[320,73,243]	-2	hSpCas9	negative selection	5357242
60723495	60723517	14	-	27760321	HT29	viability after 10 days	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.19784572802180717	[265,207]	[345,270,397]	2	hSpCas9	negative selection	5357243
60723644	60723666	14	-	27760321	HT29	viability after 10 days	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.8232480035590993	[638,498]	[1468,921,1367]	9	hSpCas9	negative selection	5357244
60723212	60723234	14	+	27760321	MOLM13	viability	CTTTTGGACTGGGTCTCGGAGG	SIX4	ENSG00000100625	0.3658005076662679	[784,780]	[617,530]	2	hSpCas9	negative selection	5440703
60723357	60723379	14	-	27760321	MOLM13	viability	AAGTCGCGCAACGCGCTCAAGG	SIX4	ENSG00000100625	1.2162553917362509	[262,254]	[276,393]	8	hSpCas9	negative selection	5440704
60723448	60723470	14	-	27760321	MOLM13	viability	GGGAGCCGTAGACAAGTACCGG	SIX4	ENSG00000100625	0.2562218675366773	[276,219]	[153,176]	1	hSpCas9	negative selection	5440705
60723495	60723517	14	-	27760321	MOLM13	viability	TACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.3688823445362688	[352,265]	[315,144]	2	hSpCas9	negative selection	5440706
60723644	60723666	14	-	27760321	MOLM13	viability	CCCAGAGCGACCTGCTACGTGG	SIX4	ENSG00000100625	0.8097026956001845	[757,638]	[691,684]	5	hSpCas9	negative selection	5440707
60723969	60723992	14	-	27661255	K562	viability	GCAGGAGGCGCACCGAGAAGTGG	SIX4	ENSG00000100625	0.20283885656000358	[663,866]	[687,710]	7	dCas9-KRAB	negative selection	5511185
60723991	60724014	14	-	27661255	K562	viability	GGATGGAAAGCGCCTCGGAAGGG	SIX4	ENSG00000100625	0.049854376806167444	[1186,1015]	[1036,807]	1	dCas9-KRAB	negative selection	5511186
60724307	60724330	14	-	27661255	K562	viability	GAGGAGTCACGTTGGGGGAACGG	SIX4	ENSG00000100625	0.11274792206845802	[888,970]	[835,772]	4	dCas9-KRAB	negative selection	5511187
60714082	60714105	14	+	27260156	BXPC3	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.11171316133200632	[435]	[404,522,535,513]	2	hSpCas9	negative selection	5570342
60713842	60713865	14	+	27260156	BXPC3	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	-0.0626962250989005	[322]	[257,333,339,371]	-1	hSpCas9	negative selection	5570343
60723313	60723336	14	-	27260156	BXPC3	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.5542909829954392	[117]	[186,109,210,224]	9	hSpCas9	negative selection	5570344
60724033	60724056	14	+	27260156	BXPC3	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.001652500934675949	[1904]	[1677,1738,2234,2416]	0	hSpCas9	negative selection	5634596
60719827	60719850	14	+	27260156	BXPC3	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.1672363161464585	[266]	[279,409,263,291]	3	hSpCas9	negative selection	5634597
60720051	60720074	14	-	27260156	BXPC3	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.07584582642960713	[371]	[480,255,351,379]	-2	hSpCas9	negative selection	5634598
60714082	60714105	14	+	27260156	A673	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.017527739077657756	[435]	[552,488,449,584]	0	hSpCas9	negative selection	5691593
60713842	60713865	14	+	27260156	A673	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.22926955587608228	[322]	[425,454,479,452]	5	hSpCas9	negative selection	5691594
60723313	60723336	14	-	27260156	A673	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.2330295499818693	[117]	[149,164,163,185]	5	hSpCas9	negative selection	5691595
60724033	60724056	14	+	27260156	A673	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.02096957147696976	[1904]	[2769,2100,2175,2288]	0	hSpCas9	negative selection	5755847
60719827	60719850	14	+	27260156	A673	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.10260822213314558	[266]	[396,301,302,383]	2	hSpCas9	negative selection	5755848
60720051	60720074	14	-	27260156	A673	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.17785852499814492	[371]	[420,420,321,418]	-4	hSpCas9	negative selection	5755849
60714082	60714105	14	+	27260156	A375	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.23861810788696633	[435]	[742,590,588,490]	3	hSpCas9	negative selection	5812844
60713842	60713865	14	+	27260156	A375	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.3948564594880455	[322]	[477,456,502,533]	6	hSpCas9	negative selection	5812845
60723313	60723336	14	-	27260156	A375	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.4075112950960873	[117]	[173,209,192,159]	6	hSpCas9	negative selection	5812846
60724033	60724056	14	+	27260156	A375	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.3482186614037963	[1904]	[3015,3235,2909,2280]	5	hSpCas9	negative selection	5877098
60719827	60719850	14	+	27260156	A375	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.49004581981454864	[266]	[448,597,392,343]	7	hSpCas9	negative selection	5877099
60720051	60720074	14	-	27260156	A375	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.02088169780145377	[371]	[570,398,371,372]	0	hSpCas9	negative selection	5877100
60714082	60714105	14	+	27260156	COLO741	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.00998587261226104	[435]	[658,646,374]	0	hSpCas9	negative selection	5934095
60713842	60713865	14	+	27260156	COLO741	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.5240885966202012	[322]	[690,625,478]	9	hSpCas9	negative selection	5934096
60723313	60723336	14	-	27260156	COLO741	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.4742052183502856	[117]	[245,204,181]	8	hSpCas9	negative selection	5934097
60724033	60724056	14	+	27260156	COLO741	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.14714100388484708	[1904]	[2710,2822,2557]	3	hSpCas9	negative selection	5998349
60719827	60719850	14	+	27260156	COLO741	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.39370504582048227	[266]	[390,515,432]	7	hSpCas9	negative selection	5998350
60720051	60720074	14	-	27260156	COLO741	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.4266567530068268	[371]	[521,295,262]	-7	hSpCas9	negative selection	5998351
60714082	60714105	14	+	27260156	CAL120	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.32829689563621384	[435]	[335,359,582]	-5	hSpCas9	negative selection	6055346
60713842	60713865	14	+	27260156	CAL120	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.4397287787940628	[322]	[683,361,608]	6	hSpCas9	negative selection	6055347
60723313	60723336	14	-	27260156	CAL120	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.7303860454829145	[117]	[128,77,64]	-8	hSpCas9	negative selection	6055348
60724033	60724056	14	+	27260156	CAL120	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.12810140940677117	[1904]	[2746,2262,2780]	2	hSpCas9	negative selection	6119600
60719827	60719850	14	+	27260156	CAL120	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.4106919380877959	[266]	[473,654,204]	6	hSpCas9	negative selection	6119601
60720051	60720074	14	-	27260156	CAL120	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	0.23234914211810653	[371]	[757,617,291]	3	hSpCas9	negative selection	6119602
60714082	60714105	14	+	27260156	CADOES1	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.317909445498496	[435]	[542,467,446,565]	5	hSpCas9	negative selection	6176597
60713842	60713865	14	+	27260156	CADOES1	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	-0.18407494618660447	[322]	[265,250,343,193]	-3	hSpCas9	negative selection	6176598
60723313	60723336	14	-	27260156	CADOES1	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.36560555627458147	[117]	[85,96,65,91]	-6	hSpCas9	negative selection	6176599
60724033	60724056	14	+	27260156	CADOES1	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.3250431497239714	[1904]	[2382,2332,2039,2117]	5	hSpCas9	negative selection	6240851
60719827	60719850	14	+	27260156	CADOES1	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.34971354390117326	[266]	[330,306,354,270]	6	hSpCas9	negative selection	6240852
60720051	60720074	14	-	27260156	CADOES1	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.3541312926455309	[371]	[283,277,292,225]	-6	hSpCas9	negative selection	6240853
60714082	60714105	14	+	27260156	EWS502	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.07742322573115024	[435]	[513,366,615,450]	1	hSpCas9	negative selection	6297848
60713842	60713865	14	+	27260156	EWS502	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	-0.0030677262127976057	[322]	[236,434,284,420]	0	hSpCas9	negative selection	6297849
60723313	60723336	14	-	27260156	EWS502	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.050544768797386785	[117]	[129,129,145,109]	0	hSpCas9	negative selection	6297850
60724033	60724056	14	+	27260156	EWS502	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.10548025857600374	[1904]	[2008,2256,1981,2460]	1	hSpCas9	negative selection	6362102
60719827	60719850	14	+	27260156	EWS502	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.6059012461244062	[266]	[447,310,375,598]	9	hSpCas9	negative selection	6362103
60720051	60720074	14	-	27260156	EWS502	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.721428894898878	[371]	[157,158,405,247]	-8	hSpCas9	negative selection	6362104
60714082	60714105	14	+	27260156	EW8	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.1787291448609269	[435]	[413,484,422,274]	3	hSpCas9	negative selection	6419099
60713842	60713865	14	+	27260156	EW8	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	-0.037973310644056846	[322]	[335,178,198,322]	0	hSpCas9	negative selection	6419100
60723313	60723336	14	-	27260156	EW8	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.12953709354066145	[117]	[37,56,48,205]	-2	hSpCas9	negative selection	6419101
60724033	60724056	14	+	27260156	EW8	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.10706088125258884	[1904]	[1946,1823,1485,1451]	2	hSpCas9	negative selection	6483353
60719827	60719850	14	+	27260156	EW8	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.21882666642088622	[266]	[278,218,139,389]	4	hSpCas9	negative selection	6483354
60720051	60720074	14	-	27260156	EW8	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.3405355770830658	[371]	[196,211,254,279]	-6	hSpCas9	negative selection	6483355
60714082	60714105	14	+	27260156	CORL105	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.05942635003910623	[435]	[471,534,631,501]	1	hSpCas9	negative selection	6540350
60713842	60713865	14	+	27260156	CORL105	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.2911072405816619	[322]	[408,399,584,474]	5	hSpCas9	negative selection	6540351
60723313	60723336	14	-	27260156	CORL105	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.04052578155837927	[117]	[151,158,170,90]	0	hSpCas9	negative selection	6540352
60724033	60724056	14	+	27260156	CORL105	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.1417204066668707	[1904]	[2122,2559,2797,2398]	2	hSpCas9	negative selection	6604604
60719827	60719850	14	+	27260156	CORL105	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.12465574207114904	[266]	[307,333,497,246]	2	hSpCas9	negative selection	6604605
60720051	60720074	14	-	27260156	CORL105	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.8018756085781861	[371]	[211,221,292,277]	-8	hSpCas9	negative selection	6604606
60714082	60714105	14	+	27260156	HS294T	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.17529739860332366	[435]	[281,140,167,156]	2	hSpCas9	negative selection	6661601
60713842	60713865	14	+	27260156	HS294T	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.17341329046275344	[322]	[112,100,86,290]	2	hSpCas9	negative selection	6661602
60723313	60723336	14	-	27260156	HS294T	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.741197416334682	[117]	[76,71,63,94]	8	hSpCas9	negative selection	6661603
60724033	60724056	14	+	27260156	HS294T	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.5268474512714119	[1904]	[800,902,897,1791]	7	hSpCas9	negative selection	6725855
60719827	60719850	14	+	27260156	HS294T	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.3189691328277234	[266]	[87,211,95,117]	4	hSpCas9	negative selection	6725856
60720051	60720074	14	-	27260156	HS294T	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	0.8230908803934767	[371]	[565,110,137,160]	9	hSpCas9	negative selection	6725857
60714082	60714105	14	+	27260156	HCC44	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.00026540223465670865	[435]	[523,382,665,444]	0	hSpCas9	negative selection	6782852
60713842	60713865	14	+	27260156	HCC44	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	-0.10464303694992838	[322]	[325,234,571,278]	-2	hSpCas9	negative selection	6782853
60723313	60723336	14	-	27260156	HCC44	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.8245410526373638	[117]	[50,23,143,97]	-8	hSpCas9	negative selection	6782854
60724033	60724056	14	+	27260156	HCC44	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.014472832305286065	[1904]	[2662,1770,2856,1633]	0	hSpCas9	negative selection	6847106
60719827	60719850	14	+	27260156	HCC44	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.26972865908508237	[266]	[360,417,397,276]	4	hSpCas9	negative selection	6847107
60720051	60720074	14	-	27260156	HCC44	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.4980876874849087	[371]	[395,225,409,198]	-6	hSpCas9	negative selection	6847108
60714082	60714105	14	+	27260156	G402	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.3324296218917068	[435]	[719,280,767,881]	4	hSpCas9	negative selection	6904103
60713842	60713865	14	+	27260156	G402	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.8694444164510179	[322]	[426,1221,510,704]	9	hSpCas9	negative selection	6904104
60723313	60723336	14	-	27260156	G402	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.3299995134995366	[117]	[132,70,14,232]	-4	hSpCas9	negative selection	6904105
60724033	60724056	14	+	27260156	G402	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.3074892521053081	[1904]	[3098,2912,2731,2789]	4	hSpCas9	negative selection	6968357
60719827	60719850	14	+	27260156	G402	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.7179647054561997	[266]	[301,658,684,471]	8	hSpCas9	negative selection	6968358
60720051	60720074	14	-	27260156	G402	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.35565637985265697	[371]	[517,227,400,289]	-4	hSpCas9	negative selection	6968359
60714082	60714105	14	+	27260156	L33	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.06008153007033998	[435]	[499,128,245,463]	-1	hSpCas9	negative selection	7025354
60713842	60713865	14	+	27260156	L33	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.29091320947685445	[322]	[254,168,296,443]	6	hSpCas9	negative selection	7025355
60723313	60723336	14	-	27260156	L33	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.08193154942838698	[117]	[208,30,56,121]	1	hSpCas9	negative selection	7025356
60724033	60724056	14	+	27260156	L33	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.15708111998358865	[1904]	[2142,882,1440,1907]	3	hSpCas9	negative selection	7089608
60719827	60719850	14	+	27260156	L33	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.19437816349037862	[266]	[251,140,236,250]	4	hSpCas9	negative selection	7089609
60720051	60720074	14	-	27260156	L33	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.39052947147435946	[371]	[261,125,154,318]	-7	hSpCas9	negative selection	7089610
60714082	60714105	14	+	27260156	K562	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.2105779334931292	[435]	[743,457,335,293]	2	hSpCas9	negative selection	7146605
60713842	60713865	14	+	27260156	K562	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.08703817596860586	[322]	[265,239,587,135]	1	hSpCas9	negative selection	7146606
60723313	60723336	14	-	27260156	K562	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.031116371409824595	[117]	[191,175,27,48]	0	hSpCas9	negative selection	7146607
60724033	60724056	14	+	27260156	K562	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	-0.0040742002397005095	[1904]	[1396,1931,1849,1560]	0	hSpCas9	negative selection	7210859
60719827	60719850	14	+	27260156	K562	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.3439573738321728	[266]	[574,85,346,214]	4	hSpCas9	negative selection	7210860
60720051	60720074	14	-	27260156	K562	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.08546758159154078	[371]	[405,231,289,317]	-1	hSpCas9	negative selection	7210861
60714082	60714105	14	+	27260156	HT29	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.054678969278374547	[435]	[624,531,565,486]	1	hSpCas9	negative selection	7267856
60713842	60713865	14	+	27260156	HT29	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.18497644518387985	[322]	[459,387,490,439]	3	hSpCas9	negative selection	7267857
60723313	60723336	14	-	27260156	HT29	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.2207213591945103	[117]	[164,169,169,162]	4	hSpCas9	negative selection	7267858
60724033	60724056	14	+	27260156	HT29	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.11660658771223886	[1904]	[2528,2992,2346,2232]	2	hSpCas9	negative selection	7332110
60719827	60719850	14	+	27260156	HT29	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.2296906975833155	[266]	[444,396,348,339]	4	hSpCas9	negative selection	7332111
60720051	60720074	14	-	27260156	HT29	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.1967144565994382	[371]	[397,460,234,476]	-4	hSpCas9	negative selection	7332112
60714082	60714105	14	+	27260156	MHHES1	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.00999757241729761	[435]	[625,427,506,407]	0	hSpCas9	negative selection	7389107
60713842	60713865	14	+	27260156	MHHES1	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.2643072930922421	[322]	[552,311,548,346]	5	hSpCas9	negative selection	7389108
60723313	60723336	14	-	27260156	MHHES1	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.04423964008247916	[117]	[88,176,128,145]	0	hSpCas9	negative selection	7389109
60724033	60724056	14	+	27260156	MHHES1	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.17711809440361925	[1904]	[2248,2739,2712,2046]	3	hSpCas9	negative selection	7453361
60719827	60719850	14	+	27260156	MHHES1	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.10098702253923153	[266]	[342,245,418,279]	1	hSpCas9	negative selection	7453362
60720051	60720074	14	-	27260156	MHHES1	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	0.09920586865601178	[371]	[588,451,568,241]	1	hSpCas9	negative selection	7453363
60714082	60714105	14	+	27260156	MEWO	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.15395379260928121	[435]	[399,415,289]	-3	hSpCas9	negative selection	7510358
60713842	60713865	14	+	27260156	MEWO	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.27314136674424766	[322]	[470,352,291]	6	hSpCas9	negative selection	7510359
60723313	60723336	14	-	27260156	MEWO	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.37207999598239927	[117]	[186,172,76]	7	hSpCas9	negative selection	7510360
60724033	60724056	14	+	27260156	MEWO	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	-0.008510006306610585	[1904]	[2052,1644,1671]	0	hSpCas9	negative selection	7574612
60719827	60719850	14	+	27260156	MEWO	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.1293425802489956	[266]	[300,271,251]	3	hSpCas9	negative selection	7574613
60720051	60720074	14	-	27260156	MEWO	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.511761439064166	[371]	[278,242,216]	-8	hSpCas9	negative selection	7574614
60714082	60714105	14	+	27260156	LNCAPCLONEFGC	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.03754475946518493	[435]	[321,441,435,343]	0	hSpCas9	negative selection	7631609
60713842	60713865	14	+	27260156	LNCAPCLONEFGC	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.21997122991954754	[322]	[263,408,381,310]	3	hSpCas9	negative selection	7631610
60723313	60723336	14	-	27260156	LNCAPCLONEFGC	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.32110566208872204	[117]	[141,83,219,103]	5	hSpCas9	negative selection	7631611
60724033	60724056	14	+	27260156	LNCAPCLONEFGC	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.17667477367233086	[1904]	[1728,1816,2255,2056]	2	hSpCas9	negative selection	7695863
60719827	60719850	14	+	27260156	LNCAPCLONEFGC	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.19928132404743915	[266]	[327,298,262,215]	3	hSpCas9	negative selection	7695864
60720051	60720074	14	-	27260156	LNCAPCLONEFGC	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.6618711049899332	[371]	[110,207,292,253]	-7	hSpCas9	negative selection	7695865
60714082	60714105	14	+	27260156	PANC0327	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.06767243518110672	[435]	[425,334,282,442]	-1	hSpCas9	negative selection	7752860
60713842	60713865	14	+	27260156	PANC0327	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.2456159523073248	[322]	[677,210,302,212]	3	hSpCas9	negative selection	7752861
60723313	60723336	14	-	27260156	PANC0327	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.9559095543906084	[117]	[104,144,361,200]	9	hSpCas9	negative selection	7752862
60724033	60724056	14	+	27260156	PANC0327	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.34451188724928583	[1904]	[2411,1667,2393,2203]	5	hSpCas9	negative selection	7817114
60719827	60719850	14	+	27260156	PANC0327	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.497114113662613	[266]	[573,188,177,435]	7	hSpCas9	negative selection	7817115
60720051	60720074	14	-	27260156	PANC0327	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.10313351107661572	[371]	[184,283,552,201]	-1	hSpCas9	negative selection	7817116
60714082	60714105	14	+	27260156	NCIH2009	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.19032856706374401	[435]	[690,761,628]	2	hSpCas9	negative selection	7874111
60713842	60713865	14	+	27260156	NCIH2009	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.6444584947650976	[322]	[738,578,805]	8	hSpCas9	negative selection	7874112
60723313	60723336	14	-	27260156	NCIH2009	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.49003008844191687	[117]	[364,155,200]	6	hSpCas9	negative selection	7874113
60724033	60724056	14	+	27260156	NCIH2009	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.5293854998463603	[1904]	[4640,3786,3248]	7	hSpCas9	negative selection	7938365
60719827	60719850	14	+	27260156	NCIH2009	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.22197185677757347	[266]	[479,346,487]	3	hSpCas9	negative selection	7938366
60720051	60720074	14	-	27260156	NCIH2009	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.3873623338713238	[371]	[536,286,396]	-5	hSpCas9	negative selection	7938367
60714082	60714105	14	+	27260156	NCIH1373	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.7440631013626731	[435]	[1119,729,524,253]	7	hSpCas9	negative selection	7995362
60713842	60713865	14	+	27260156	NCIH1373	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	1.1034559855143737	[322]	[356,1031,797,217]	9	hSpCas9	negative selection	7995363
60723313	60723336	14	-	27260156	NCIH1373	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.42809538115248813	[117]	[104,25,152,117]	4	hSpCas9	negative selection	7995364
60724033	60724056	14	+	27260156	NCIH1373	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.6532800871945708	[1904]	[3302,3197,3109,1010]	6	hSpCas9	negative selection	8059616
60719827	60719850	14	+	27260156	NCIH1373	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	-0.17115736761433498	[266]	[303,190,253,86]	-2	hSpCas9	negative selection	8059617
60720051	60720074	14	-	27260156	NCIH1373	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	0.29117105225244755	[371]	[534,271,388,235]	3	hSpCas9	negative selection	8059618
60714082	60714105	14	+	27260156	PATU8902	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.0330473919018647	[435]	[698,578,679,489]	0	hSpCas9	negative selection	8116613
60713842	60713865	14	+	27260156	PATU8902	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.47660024885650837	[322]	[653,631,713,454]	5	hSpCas9	negative selection	8116614
60723313	60723336	14	-	27260156	PATU8902	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.6587399118111721	[117]	[105,112,161,7]	-6	hSpCas9	negative selection	8116615
60724033	60724056	14	+	27260156	PATU8902	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.3727565320648689	[1904]	[3241,3953,2106,4939]	4	hSpCas9	negative selection	8180867
60719827	60719850	14	+	27260156	PATU8902	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.6499063683060456	[266]	[425,1095,224,691]	6	hSpCas9	negative selection	8180868
60720051	60720074	14	-	27260156	PATU8902	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.6445703050779572	[371]	[285,241,345,460]	-6	hSpCas9	negative selection	8180869
60714082	60714105	14	+	27260156	PANC1	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.4259802373887799	[435]	[499,791,441,353]	7	hSpCas9	negative selection	8237864
60713842	60713865	14	+	27260156	PANC1	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.032362679083504764	[322]	[194,392,371,207]	0	hSpCas9	negative selection	8237865
60723313	60723336	14	-	27260156	PANC1	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.21310271129595892	[117]	[106,212,100,73]	3	hSpCas9	negative selection	8237866
60724033	60724056	14	+	27260156	PANC1	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.1267402323373643	[1904]	[1621,2291,1685,1645]	2	hSpCas9	negative selection	8302118
60719827	60719850	14	+	27260156	PANC1	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.19161762543882865	[266]	[246,289,215,290]	3	hSpCas9	negative selection	8302119
60720051	60720074	14	-	27260156	PANC1	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.3169049611947323	[371]	[273,199,233,294]	-5	hSpCas9	negative selection	8302120
60714082	60714105	14	+	27260156	PANC0813	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.14722696427321366	[435]	[596,553,647,476]	2	hSpCas9	negative selection	8359115
60713842	60713865	14	+	27260156	PANC0813	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.1630635263172161	[322]	[439,412,388,455]	2	hSpCas9	negative selection	8359116
60723313	60723336	14	-	27260156	PANC0813	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.03759422652162692	[117]	[123,136,193,113]	0	hSpCas9	negative selection	8359117
60724033	60724056	14	+	27260156	PANC0813	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.12980013007424374	[1904]	[2634,1984,2511,2662]	2	hSpCas9	negative selection	8423369
60719827	60719850	14	+	27260156	PANC0813	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.2970014114505476	[266]	[371,245,429,485]	5	hSpCas9	negative selection	8423370
60720051	60720074	14	-	27260156	PANC0813	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.36670780415385995	[371]	[210,357,424,348]	-5	hSpCas9	negative selection	8423371
60714082	60714105	14	+	27260156	RDES	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.21947690135327946	[435]	[486,592,649,613]	3	hSpCas9	negative selection	8480366
60713842	60713865	14	+	27260156	RDES	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.2560186848089536	[322]	[288,541,477,483]	4	hSpCas9	negative selection	8480367
60723313	60723336	14	-	27260156	RDES	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.47911954669265056	[117]	[191,158,200,202]	7	hSpCas9	negative selection	8480368
60724033	60724056	14	+	27260156	RDES	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.17606384287085586	[1904]	[2350,2147,2605,2831]	3	hSpCas9	negative selection	8544620
60719827	60719850	14	+	27260156	RDES	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.0889318742655234	[266]	[294,301,332,383]	1	hSpCas9	negative selection	8544621
60720051	60720074	14	-	27260156	RDES	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.27562157856249314	[371]	[282,350,333,466]	-5	hSpCas9	negative selection	8544622
60714082	60714105	14	+	27260156	PC3	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.23448483327759473	[435]	[217,404,485,446]	-5	hSpCas9	negative selection	8601617
60713842	60713865	14	+	27260156	PC3	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.4833836394402261	[322]	[315,552,560,414]	8	hSpCas9	negative selection	8601618
60723313	60723336	14	-	27260156	PC3	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.1707726729456831	[117]	[105,77,138,92]	-4	hSpCas9	negative selection	8601619
60724033	60724056	14	+	27260156	PC3	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	-0.0704692873507291	[1904]	[1028,2137,3032,1661]	-1	hSpCas9	negative selection	8665871
60719827	60719850	14	+	27260156	PC3	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	-0.06786369187530183	[266]	[158,275,493,192]	-1	hSpCas9	negative selection	8665872
60720051	60720074	14	-	27260156	PC3	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.7348630887774049	[371]	[115,252,329,261]	-9	hSpCas9	negative selection	8665873
60714082	60714105	14	+	27260156	PATU8988T	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.18689802235657565	[435]	[326,391,315,454]	-3	hSpCas9	negative selection	8722868
60713842	60713865	14	+	27260156	PATU8988T	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	-0.1361461783640474	[322]	[237,283,234,387]	-2	hSpCas9	negative selection	8722869
60723313	60723336	14	-	27260156	PATU8988T	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.13695984856599064	[117]	[195,132,31,143]	2	hSpCas9	negative selection	8722870
60724033	60724056	14	+	27260156	PATU8988T	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.07005854385321575	[1904]	[1809,2267,1460,2253]	1	hSpCas9	negative selection	8787122
60719827	60719850	14	+	27260156	PATU8988T	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.7205788428979191	[266]	[332,441,422,510]	9	hSpCas9	negative selection	8787123
60720051	60720074	14	-	27260156	PATU8988T	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.8038719827215192	[371]	[66,275,202,290]	-8	hSpCas9	negative selection	8787124
60714082	60714105	14	+	27260156	T47D	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.08149083973993973	[435]	[486,477,500,452]	-2	hSpCas9	negative selection	8844119
60713842	60713865	14	+	27260156	T47D	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.16331999998413482	[322]	[482,405,391,405]	3	hSpCas9	negative selection	8844120
60723313	60723336	14	-	27260156	T47D	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.00037070810258055253	[117]	[185,145,127,87]	0	hSpCas9	negative selection	8844121
60724033	60724056	14	+	27260156	T47D	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.01932556756808479	[1904]	[2194,2137,2113,2570]	0	hSpCas9	negative selection	8908373
60719827	60719850	14	+	27260156	T47D	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.22777329789420186	[266]	[343,362,416,330]	5	hSpCas9	negative selection	8908374
60720051	60720074	14	-	27260156	T47D	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.26050195530733067	[371]	[344,371,426,298]	-5	hSpCas9	negative selection	8908375
60714082	60714105	14	+	27260156	SU8686	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.1743702303062632	[435]	[418,442,507,611]	3	hSpCas9	negative selection	8965370
60713842	60713865	14	+	27260156	SU8686	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.22938567051024722	[322]	[287,338,480,414]	4	hSpCas9	negative selection	8965371
60723313	60723336	14	-	27260156	SU8686	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.11822139462817893	[117]	[166,108,100,126]	2	hSpCas9	negative selection	8965372
60724033	60724056	14	+	27260156	SU8686	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.08220948049442889	[1904]	[1839,1733,2293,2209]	1	hSpCas9	negative selection	9029624
60719827	60719850	14	+	27260156	SU8686	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.31842660920739263	[266]	[313,265,274,498]	5	hSpCas9	negative selection	9029625
60720051	60720074	14	-	27260156	SU8686	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.471348132937655	[371]	[200,323,252,286]	-6	hSpCas9	negative selection	9029626
60714082	60714105	14	+	27260156	SKES1	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.12795821824302392	[435]	[819,361,432,332]	3	hSpCas9	negative selection	9086621
60713842	60713865	14	+	27260156	SKES1	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.1887860386033231	[322]	[352,473,333,320]	4	hSpCas9	negative selection	9086622
60723313	60723336	14	-	27260156	SKES1	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	-0.19540756937625137	[117]	[106,87,133,81]	-4	hSpCas9	negative selection	9086623
60724033	60724056	14	+	27260156	SKES1	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.06521148394867282	[1904]	[2581,2084,1911,1505]	1	hSpCas9	negative selection	9150875
60719827	60719850	14	+	27260156	SKES1	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.19111493936206003	[266]	[331,341,282,268]	4	hSpCas9	negative selection	9150876
60720051	60720074	14	-	27260156	SKES1	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.52643432318926	[371]	[245,318,292,183]	-8	hSpCas9	negative selection	9150877
60714082	60714105	14	+	27260156	TOV112D	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.5464704182497684	[435]	[591,610,532,798]	8	hSpCas9	negative selection	9207872
60713842	60713865	14	+	27260156	TOV112D	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.5241177890584102	[322]	[419,751,258,494]	8	hSpCas9	negative selection	9207873
60723313	60723336	14	-	27260156	TOV112D	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	1.005928594902592	[117]	[183,326,234,220]	9	hSpCas9	negative selection	9207874
60724033	60724056	14	+	27260156	TOV112D	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.03149641335736808	[1904]	[1686,2141,2002,1988]	0	hSpCas9	negative selection	9272126
60719827	60719850	14	+	27260156	TOV112D	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.4542794362589393	[266]	[450,483,235,330]	8	hSpCas9	negative selection	9272127
60720051	60720074	14	-	27260156	TOV112D	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.3299034309371137	[371]	[275,379,322,226]	-6	hSpCas9	negative selection	9272128
60714082	60714105	14	+	27260156	TC71	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.053815867482720076	[435]	[338,509,489,463]	-1	hSpCas9	negative selection	9329123
60713842	60713865	14	+	27260156	TC71	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.15309666250137177	[322]	[343,429,341,428]	4	hSpCas9	negative selection	9329124
60723313	60723336	14	-	27260156	TC71	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.4088949957466155	[117]	[198,146,190,130]	8	hSpCas9	negative selection	9329125
60724033	60724056	14	+	27260156	TC71	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	-0.0025365929757650285	[1904]	[1837,2188,2094,2033]	0	hSpCas9	negative selection	9393377
60719827	60719850	14	+	27260156	TC71	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.24405533872423701	[266]	[307,329,280,445]	6	hSpCas9	negative selection	9393378
60720051	60720074	14	-	27260156	TC71	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.32066339179720327	[371]	[332,287,288,370]	-7	hSpCas9	negative selection	9393379
60714082	60714105	14	+	27260156	TC32	viability	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.09095136220123856	[435]	[362,355,475,578]	1	hSpCas9	negative selection	9450374
60713842	60713865	14	+	27260156	TC32	viability	AATGTCGCGGTTTAGCTCAGTGG	SIX4	ENSG00000100625	0.006068327766097892	[322]	[273,279,463,217]	0	hSpCas9	negative selection	9450375
60723313	60723336	14	-	27260156	TC32	viability	ACCCTTCGCCCGCCGAGAAGCGG	SIX4	ENSG00000100625	0.05113383233671209	[117]	[181,27,132,138]	0	hSpCas9	negative selection	9450376
60724033	60724056	14	+	27260156	TC32	viability	CGCCGCACTTGCGATCTGCCCGG	SIX4	ENSG00000100625	0.014711879689170537	[1904]	[1683,1338,2267,2126]	0	hSpCas9	negative selection	9514628
60719827	60719850	14	+	27260156	TC32	viability	CTGGCTGTTTGCTCCGGAATTGG	SIX4	ENSG00000100625	0.8088910887562275	[266]	[587,380,403,346]	9	hSpCas9	negative selection	9514629
60720051	60720074	14	-	27260156	TC32	viability	GTCTACTTCCCAGGACGTGAAGG	SIX4	ENSG00000100625	-0.09924971317934422	[371]	[241,282,470,342]	-2	hSpCas9	negative selection	9514630
60713430	60713453	14	-	27869803	HPAFII	viability after 27 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.22998909854364147	[160]	[197,16,NaN]	1	hSpCas9	negative selection	9551954
60714082	60714105	14	+	27869803	HPAFII	viability after 27 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.2962520232561696	[285]	[224,150,NaN]	2	hSpCas9	negative selection	9551955
60720318	60720341	14	+	27869803	HPAFII	viability after 27 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.3071705663298755	[539]	[211,243,NaN]	-2	hSpCas9	negative selection	9551956
60723439	60723462	14	-	27869803	HPAFII	viability after 27 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	-0.07670266121224945	[183]	[82,98,NaN]	0	hSpCas9	negative selection	9551957
60723456	60723479	14	+	27869803	HPAFII	viability after 27 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	0.8148886860213939	[97]	[130,56,NaN]	6	hSpCas9	negative selection	9551958
60723987	60724010	14	-	27869803	HPAFII	viability after 27 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.71141998675077	[48]	[45,38,NaN]	6	hSpCas9	negative selection	9551959
60713430	60713453	14	-	27869803	HPAFII	viability after 15 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.4669138595652552	[160]	[470,94,NaN]	5	hSpCas9	negative selection	9634403
60714082	60714105	14	+	27869803	HPAFII	viability after 15 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.3934128529510721	[285]	[576,295,NaN]	4	hSpCas9	negative selection	9634404
60720318	60720341	14	+	27869803	HPAFII	viability after 15 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.3437414931843433	[539]	[452,459,NaN]	-4	hSpCas9	negative selection	9634405
60723439	60723462	14	-	27869803	HPAFII	viability after 15 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.17570494713926998	[183]	[350,143,NaN]	2	hSpCas9	negative selection	9634406
60723456	60723479	14	+	27869803	HPAFII	viability after 15 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	0.43618764189355885	[97]	[197,107,NaN]	5	hSpCas9	negative selection	9634407
60723987	60724010	14	-	27869803	HPAFII	viability after 15 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	-0.0410205077812682	[48]	[73,36,NaN]	0	hSpCas9	negative selection	9634408
60713430	60713453	14	-	27869803	ASPC1	viability after 36 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	-0.3118263670697692	[540]	[251,119,105]	-3	hSpCas9	negative selection	9716852
60714082	60714105	14	+	27869803	ASPC1	viability after 36 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	-0.06171482363469574	[681]	[386,308,49]	0	hSpCas9	negative selection	9716853
60720318	60720341	14	+	27869803	ASPC1	viability after 36 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	0.48450168372682634	[1209]	[417,910,451]	5	hSpCas9	negative selection	9716854
60723439	60723462	14	-	27869803	ASPC1	viability after 36 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.9928616479883614	[444]	[74,525,297]	8	hSpCas9	negative selection	9716855
60723456	60723479	14	+	27869803	ASPC1	viability after 36 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	-0.289199939945181	[509]	[73,372,13]	-3	hSpCas9	negative selection	9716856
60723987	60724010	14	-	27869803	ASPC1	viability after 36 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.007175051146486089	[186]	[206,0,16]	0	hSpCas9	negative selection	9716857
60713430	60713453	14	-	27869803	PATU8988S	viability after 35 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.3447196744677724	[457]	[341,125,NaN]	4	hSpCas9	negative selection	9799301
60714082	60714105	14	+	27869803	PATU8988S	viability after 35 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.66719499108902	[574]	[256,478,NaN]	7	hSpCas9	negative selection	9799302
60720318	60720341	14	+	27869803	PATU8988S	viability after 35 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	0.4376676179574499	[920]	[456,547,NaN]	5	hSpCas9	negative selection	9799303
60723439	60723462	14	-	27869803	PATU8988S	viability after 35 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	-0.6809913999693388	[536]	[90,178,NaN]	-6	hSpCas9	negative selection	9799304
60723456	60723479	14	+	27869803	PATU8988S	viability after 35 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	0.6781513807934587	[463]	[306,290,NaN]	7	hSpCas9	negative selection	9799305
60723987	60724010	14	-	27869803	PATU8988S	viability after 35 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.006346400724589696	[166]	[91,42,NaN]	0	hSpCas9	negative selection	9799306
60713430	60713453	14	-	27869803	PATU8988S	viability after 31 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.1514869322117679	[457]	[219,180,NaN]	2	hSpCas9	negative selection	9881750
60714082	60714105	14	+	27869803	PATU8988S	viability after 31 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.9616789717090247	[574]	[325,599,NaN]	9	hSpCas9	negative selection	9881751
60720318	60720341	14	+	27869803	PATU8988S	viability after 31 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	0.4349510309941478	[920]	[411,603,NaN]	5	hSpCas9	negative selection	9881752
60723439	60723462	14	-	27869803	PATU8988S	viability after 31 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	-0.6048958565798476	[536]	[98,193,NaN]	-6	hSpCas9	negative selection	9881753
60723456	60723479	14	+	27869803	PATU8988S	viability after 31 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	0.5763704511638077	[463]	[263,290,NaN]	7	hSpCas9	negative selection	9881754
60723987	60724010	14	-	27869803	PATU8988S	viability after 31 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	0.04549148405654457	[166]	[84,47,NaN]	0	hSpCas9	negative selection	9881755
60713430	60713453	14	-	27869803	HPAFII	viability after 35 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.7472044688439665	[160]	[228,32,NaN]	5	hSpCas9	negative selection	9964199
60714082	60714105	14	+	27869803	HPAFII	viability after 35 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.12010313156125146	[285]	[162,150,NaN]	0	hSpCas9	negative selection	9964200
60720318	60720341	14	+	27869803	HPAFII	viability after 35 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.01152629168321151	[539]	[194,356,NaN]	0	hSpCas9	negative selection	9964201
60723439	60723462	14	-	27869803	HPAFII	viability after 35 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.4144693447846791	[183]	[70,183,NaN]	2	hSpCas9	negative selection	9964202
60723456	60723479	14	+	27869803	HPAFII	viability after 35 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	1.6276335121446357	[97]	[173,129,NaN]	9	hSpCas9	negative selection	9964203
60723987	60724010	14	-	27869803	HPAFII	viability after 35 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	-0.1167656592811186	[48]	[12,33,NaN]	0	hSpCas9	negative selection	9964204
60713430	60713453	14	-	27869803	HPAFII	viability after 31 days	CAAGCTCCAGACTGTCCAGCTGG	SIX4	ENSG00000100625	0.5582790216954984	[160]	[189,70,NaN]	4	hSpCas9	negative selection	10046648
60714082	60714105	14	+	27869803	HPAFII	viability after 31 days	AACCGTGTATACCACTGCACTGG	SIX4	ENSG00000100625	0.032182457095038225	[285]	[166,160,NaN]	0	hSpCas9	negative selection	10046649
60720318	60720341	14	+	27869803	HPAFII	viability after 31 days	CTGGCTCCATATGACTGGAAAGG	SIX4	ENSG00000100625	-0.5432524159983573	[539]	[195,220,NaN]	-4	hSpCas9	negative selection	10046650
60723439	60723462	14	-	27869803	HPAFII	viability after 31 days	TAGACAAGTACCGGCTGCGCAGG	SIX4	ENSG00000100625	0.04345410849032311	[183]	[126,83,NaN]	0	hSpCas9	negative selection	10046651
60723456	60723479	14	+	27869803	HPAFII	viability after 31 days	TGTCTACGGCTCCCAGCGGCCGG	SIX4	ENSG00000100625	0.7611405249596921	[97]	[97,87,NaN]	5	hSpCas9	negative selection	10046652
60723987	60724010	14	-	27869803	HPAFII	viability after 31 days	GGAAAGCGCCTCGGAAGGGCAGG	SIX4	ENSG00000100625	-0.8827156648150325	[48]	[12,16,NaN]	-5	hSpCas9	negative selection	10046653
60723966	60723989	14	-	28162770	P31FUJ	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	1.017424425118795	[65]	[156]	9	hSpCas9	negative selection	10234586
60723250	60723273	14	-	28162770	P31FUJ	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	0.2654486631134466	[159]	[225]	3	hSpCas9	negative selection	10234587
60724032	60724055	14	-	28162770	P31FUJ	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.4559961072913175	[133]	[215]	5	hSpCas9	negative selection	10234588
60723996	60724019	14	-	28162770	P31FUJ	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.04959752628634617	[73]	[89]	0	hSpCas9	negative selection	10234589
60723858	60723881	14	-	28162770	P31FUJ	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-3.850186182827912	[269]	[21]	-9	hSpCas9	negative selection	10234590
60723706	60723729	14	-	28162770	P31FUJ	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	0.6847356353936487	[26]	[50]	7	hSpCas9	negative selection	10234591
60723582	60723605	14	+	28162770	P31FUJ	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.0486107307342698	[324]	[394]	0	hSpCas9	negative selection	10234592
60723540	60723563	14	+	28162770	P31FUJ	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.8764268653403798	[266]	[575]	8	hSpCas9	negative selection	10234593
60723519	60723542	14	+	28162770	P31FUJ	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	-0.23280220441437827	[56]	[56]	-2	hSpCas9	negative selection	10234594
60723495	60723518	14	-	28162770	P31FUJ	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.4452697006982589	[54]	[87]	5	hSpCas9	negative selection	10234595
60723966	60723989	14	-	28162770	TF1	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10403952
60723250	60723273	14	-	28162770	TF1	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10403953
60724032	60724055	14	-	28162770	TF1	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	NaN	[NaN]	[145]	1	hSpCas9	negative selection	10403954
60723996	60724019	14	-	28162770	TF1	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10403955
60723858	60723881	14	-	28162770	TF1	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10403956
60723706	60723729	14	-	28162770	TF1	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10403957
60723582	60723605	14	+	28162770	TF1	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	NaN	[NaN]	[146]	1	hSpCas9	negative selection	10403958
60723540	60723563	14	+	28162770	TF1	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	NaN	[NaN]	[275]	1	hSpCas9	negative selection	10403959
60723519	60723542	14	+	28162770	TF1	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	NaN	[NaN]	[16]	1	hSpCas9	negative selection	10403960
60723495	60723518	14	-	28162770	TF1	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10403961
60723966	60723989	14	-	28162770	SKM1	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	0.34792330342030686	[27]	[62]	3	hSpCas9	negative selection	10573318
60723250	60723273	14	-	28162770	SKM1	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	1.2609876666490258	[37]	[160]	9	hSpCas9	negative selection	10573319
60724032	60724055	14	-	28162770	SKM1	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	-0.12539384147194044	[28]	[46]	-1	hSpCas9	negative selection	10573320
60723996	60724019	14	-	28162770	SKM1	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.4655748920745799	[33]	[82]	4	hSpCas9	negative selection	10573321
60723858	60723881	14	-	28162770	SKM1	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-3.926338357836741	[85]	[9]	-9	hSpCas9	negative selection	10573322
60723706	60723729	14	-	28162770	SKM1	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	0.5930358012568386	[11]	[31]	6	hSpCas9	negative selection	10573323
60723582	60723605	14	+	28162770	SKM1	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.2584882198383624	[60]	[128]	2	hSpCas9	negative selection	10573324
60723540	60723563	14	+	28162770	SKM1	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.6273057033415844	[77]	[212]	6	hSpCas9	negative selection	10573325
60723519	60723542	14	+	28162770	SKM1	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	0.4734541855041656	[10]	[26]	4	hSpCas9	negative selection	10573326
60723495	60723518	14	-	28162770	SKM1	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.9004643264490855	[19]	[65]	8	hSpCas9	negative selection	10573327
60723966	60723989	14	-	28162770	SKM1	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	0.34792330342030686	[27]	[62]	3	hSpCas9	negative selection	10742684
60723250	60723273	14	-	28162770	SKM1	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	1.2609876666490258	[37]	[160]	9	hSpCas9	negative selection	10742685
60724032	60724055	14	-	28162770	SKM1	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	-0.12539384147194044	[28]	[46]	-1	hSpCas9	negative selection	10742686
60723996	60724019	14	-	28162770	SKM1	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.4655748920745799	[33]	[82]	4	hSpCas9	negative selection	10742687
60723858	60723881	14	-	28162770	SKM1	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-3.926338357836741	[85]	[9]	-9	hSpCas9	negative selection	10742688
60723706	60723729	14	-	28162770	SKM1	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	0.5930358012568386	[11]	[31]	6	hSpCas9	negative selection	10742689
60723582	60723605	14	+	28162770	SKM1	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.2584882198383624	[60]	[128]	2	hSpCas9	negative selection	10742690
60723540	60723563	14	+	28162770	SKM1	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.6273057033415844	[77]	[212]	6	hSpCas9	negative selection	10742691
60723519	60723542	14	+	28162770	SKM1	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	0.4734541855041656	[10]	[26]	4	hSpCas9	negative selection	10742692
60723495	60723518	14	-	28162770	SKM1	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.9004643264490855	[19]	[65]	8	hSpCas9	negative selection	10742693
60723966	60723989	14	-	28162770	PL21	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	-0.46499323491581934	[110]	[34]	-3	hSpCas9	negative selection	10912050
60723250	60723273	14	-	28162770	PL21	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	-1.259292004147977	[120]	[21]	-7	hSpCas9	negative selection	10912051
60724032	60724055	14	-	28162770	PL21	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.3341569624610078	[112]	[61]	3	hSpCas9	negative selection	10912052
60723996	60724019	14	-	28162770	PL21	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.4982209674223147	[121]	[74]	4	hSpCas9	negative selection	10912053
60723858	60723881	14	-	28162770	PL21	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-1.368703220868559	[355]	[59]	-7	hSpCas9	negative selection	10912054
60723706	60723729	14	-	28162770	PL21	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	0.40659049195674646	[25]	[14]	3	hSpCas9	negative selection	10912055
60723582	60723605	14	+	28162770	PL21	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.9437998612295346	[128]	[107]	7	hSpCas9	negative selection	10912056
60723540	60723563	14	+	28162770	PL21	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.2903374234608984	[185]	[98]	2	hSpCas9	negative selection	10912057
60723519	60723542	14	+	28162770	PL21	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	0.8975768444688887	[36]	[29]	7	hSpCas9	negative selection	10912058
60723495	60723518	14	-	28162770	PL21	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.7684233740638459	[57]	[42]	6	hSpCas9	negative selection	10912059
60723966	60723989	14	-	28162770	P31FUJ	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	1.017424425118795	[65]	[156]	9	hSpCas9	negative selection	11081416
60723250	60723273	14	-	28162770	P31FUJ	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	0.2654486631134466	[159]	[225]	3	hSpCas9	negative selection	11081417
60724032	60724055	14	-	28162770	P31FUJ	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.4559961072913175	[133]	[215]	5	hSpCas9	negative selection	11081418
60723996	60724019	14	-	28162770	P31FUJ	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.04959752628634617	[73]	[89]	0	hSpCas9	negative selection	11081419
60723858	60723881	14	-	28162770	P31FUJ	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-3.850186182827912	[269]	[21]	-9	hSpCas9	negative selection	11081420
60723706	60723729	14	-	28162770	P31FUJ	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	0.6847356353936487	[26]	[50]	7	hSpCas9	negative selection	11081421
60723582	60723605	14	+	28162770	P31FUJ	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.0486107307342698	[324]	[394]	0	hSpCas9	negative selection	11081422
60723540	60723563	14	+	28162770	P31FUJ	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.8764268653403798	[266]	[575]	8	hSpCas9	negative selection	11081423
60723519	60723542	14	+	28162770	P31FUJ	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	-0.23280220441437827	[56]	[56]	-2	hSpCas9	negative selection	11081424
60723495	60723518	14	-	28162770	P31FUJ	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.4452697006982589	[54]	[87]	5	hSpCas9	negative selection	11081425
60723966	60723989	14	-	28162770	OCIAML5	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	1.1328265367457946	[47]	[189]	8	hSpCas9	negative selection	11250782
60723250	60723273	14	-	28162770	OCIAML5	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	1.205383701319903	[79]	[332]	8	hSpCas9	negative selection	11250783
60724032	60724055	14	-	28162770	OCIAML5	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.7108696235271604	[65]	[194]	6	hSpCas9	negative selection	11250784
60723996	60724019	14	-	28162770	OCIAML5	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	-0.8520665708639972	[47]	[47]	-5	hSpCas9	negative selection	11250785
60723858	60723881	14	-	28162770	OCIAML5	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-4.115100976697791	[143]	[14]	-9	hSpCas9	negative selection	11250786
60723706	60723729	14	-	28162770	OCIAML5	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	3.3311552531917723	[5]	[108]	9	hSpCas9	negative selection	11250787
60723582	60723605	14	+	28162770	OCIAML5	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.9627634717557538	[109]	[386]	8	hSpCas9	negative selection	11250788
60723540	60723563	14	+	28162770	OCIAML5	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.4903256265830811	[195]	[496]	4	hSpCas9	negative selection	11250789
60723519	60723542	14	+	28162770	OCIAML5	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	0.0739328476922263	[19]	[37]	0	hSpCas9	negative selection	11250790
60723495	60723518	14	-	28162770	OCIAML5	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	-0.7627992327669095	[46]	[49]	-5	hSpCas9	negative selection	11250791
60723966	60723989	14	-	28162770	EOL1	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	1.1278759312800606	[184]	[212]	8	hSpCas9	negative selection	11420148
60723250	60723273	14	-	28162770	EOL1	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	-1.916754482410407	[128]	[17]	-8	hSpCas9	negative selection	11420149
60724032	60724055	14	-	28162770	EOL1	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.397799884794674	[254]	[176]	3	hSpCas9	negative selection	11420150
60723996	60724019	14	-	28162770	EOL1	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	2.5754243890230315	[163]	[514]	9	hSpCas9	negative selection	11420151
60723858	60723881	14	-	28162770	EOL1	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-4.685625291947901	[634]	[12]	-9	hSpCas9	negative selection	11420152
60723706	60723729	14	-	28162770	EOL1	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	1.3395852708493783	[68]	[91]	9	hSpCas9	negative selection	11420153
60723582	60723605	14	+	28162770	EOL1	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.8977061593518934	[216]	[212]	7	hSpCas9	negative selection	11420154
60723540	60723563	14	+	28162770	EOL1	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.9536102371729973	[343]	[350]	7	hSpCas9	negative selection	11420155
60723519	60723542	14	+	28162770	EOL1	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	-1.5348838470667632	[54]	[9]	-7	hSpCas9	negative selection	11420156
60723495	60723518	14	-	28162770	EOL1	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.3011111230347425	[56]	[36]	2	hSpCas9	negative selection	11420157
60723966	60723989	14	-	28162770	MOLM13	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	1.052851882265735	[151]	[227]	7	hSpCas9	negative selection	11589514
60723250	60723273	14	-	28162770	MOLM13	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	1.4270171001290506	[178]	[347]	9	hSpCas9	negative selection	11589515
60724032	60724055	14	-	28162770	MOLM13	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.589451361425492	[181]	[197]	4	hSpCas9	negative selection	11589516
60723996	60724019	14	-	28162770	MOLM13	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	-0.15525631306446552	[133]	[86]	-1	hSpCas9	negative selection	11589517
60723858	60723881	14	-	28162770	MOLM13	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-7.426928381763365	[475]	[1]	-9	hSpCas9	negative selection	11589518
60723706	60723729	14	-	28162770	MOLM13	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	1.7373500565378057	[55]	[134]	9	hSpCas9	negative selection	11589519
60723582	60723605	14	+	28162770	MOLM13	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.07680661441745767	[218]	[166]	0	hSpCas9	negative selection	11589520
60723540	60723563	14	+	28162770	MOLM13	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.27854692627502564	[373]	[327]	2	hSpCas9	negative selection	11589521
60723519	60723542	14	+	28162770	MOLM13	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	-1.5321106184554214	[63]	[15]	-6	hSpCas9	negative selection	11589522
60723495	60723518	14	-	28162770	MOLM13	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	-1.7219351773354383	[72]	[15]	-7	hSpCas9	negative selection	11589523
60723966	60723989	14	-	28162770	HEL	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	0.7706563069210937	[150]	[164]	6	hSpCas9	negative selection	11758880
60723250	60723273	14	-	28162770	HEL	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	1.5481019578622814	[125]	[235]	9	hSpCas9	negative selection	11758881
60724032	60724055	14	-	28162770	HEL	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.8404194998400512	[142]	[163]	7	hSpCas9	negative selection	11758882
60723996	60724019	14	-	28162770	HEL	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	1.1968403690167526	[125]	[184]	9	hSpCas9	negative selection	11758883
60723858	60723881	14	-	28162770	HEL	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-4.646022398951806	[429]	[10]	-9	hSpCas9	negative selection	11758884
60723706	60723729	14	-	28162770	HEL	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	-0.9422236687207994	[62]	[20]	-5	hSpCas9	negative selection	11758885
60723582	60723605	14	+	28162770	HEL	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	-0.11263879927972958	[183]	[108]	-1	hSpCas9	negative selection	11758886
60723540	60723563	14	+	28162770	HEL	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.6982339445920607	[305]	[317]	6	hSpCas9	negative selection	11758887
60723519	60723542	14	+	28162770	HEL	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	0.09019780897157847	[65]	[44]	0	hSpCas9	negative selection	11758888
60723495	60723518	14	-	28162770	HEL	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	1.1436370679330388	[52]	[74]	8	hSpCas9	negative selection	11758889
60723966	60723989	14	-	28162770	MV411	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	0.7999785738115543	[74]	[109]	7	hSpCas9	negative selection	11928246
60723250	60723273	14	-	28162770	MV411	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	-1.0429549706714805	[180]	[73]	-6	hSpCas9	negative selection	11928247
60724032	60724055	14	-	28162770	MV411	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	0.1949701308886398	[83]	[80]	1	hSpCas9	negative selection	11928248
60723996	60724019	14	-	28162770	MV411	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	0.5284577020899315	[92]	[112]	5	hSpCas9	negative selection	11928249
60723858	60723881	14	-	28162770	MV411	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-3.8251902493046224	[386]	[22]	-9	hSpCas9	negative selection	11928250
60723706	60723729	14	-	28162770	MV411	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	0.40970897968165265	[41]	[46]	3	hSpCas9	negative selection	11928251
60723582	60723605	14	+	28162770	MV411	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.3896901337405331	[192]	[212]	3	hSpCas9	negative selection	11928252
60723540	60723563	14	+	28162770	MV411	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	0.40624458774093275	[274]	[306]	3	hSpCas9	negative selection	11928253
60723519	60723542	14	+	28162770	MV411	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	1.3405469551742568	[29]	[63]	9	hSpCas9	negative selection	11928254
60723495	60723518	14	-	28162770	MV411	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	1.311567888202491	[21]	[45]	9	hSpCas9	negative selection	11928255
60723966	60723989	14	-	28162770	MONOMAC1	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	-0.547944008918682	[87]	[68]	-4	hSpCas9	negative selection	12097612
60723250	60723273	14	-	28162770	MONOMAC1	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	-0.9214024044461263	[75]	[45]	-6	hSpCas9	negative selection	12097613
60724032	60724055	14	-	28162770	MONOMAC1	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	-0.2111120322712764	[102]	[101]	-2	hSpCas9	negative selection	12097614
60723996	60724019	14	-	28162770	MONOMAC1	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	-0.5330860501915686	[76]	[60]	-4	hSpCas9	negative selection	12097615
60723858	60723881	14	-	28162770	MONOMAC1	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-2.5716719922777607	[222]	[42]	-9	hSpCas9	negative selection	12097616
60723706	60723729	14	-	28162770	MONOMAC1	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	0.5399287471066525	[26]	[44]	5	hSpCas9	negative selection	12097617
60723582	60723605	14	+	28162770	MONOMAC1	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	-0.485162233856178	[115]	[94]	-4	hSpCas9	negative selection	12097618
60723540	60723563	14	+	28162770	MONOMAC1	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	1.4803954237970338	[140]	[450]	9	hSpCas9	negative selection	12097619
60723519	60723542	14	+	28162770	MONOMAC1	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	-0.6120743463383977	[43]	[32]	-5	hSpCas9	negative selection	12097620
60723495	60723518	14	-	28162770	MONOMAC1	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	1.3700037456643401	[26]	[79]	9	hSpCas9	negative selection	12097621
60723966	60723989	14	-	28162770	OCIAML2	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	0.7273095523697477	[16]	[155]	7	hSpCas9	negative selection	12266978
60723250	60723273	14	-	28162770	OCIAML2	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	0.018755015496763783	[25]	[145]	0	hSpCas9	negative selection	12266979
60724032	60724055	14	-	28162770	OCIAML2	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	1.177068430826958	[14]	[187]	9	hSpCas9	negative selection	12266980
60723996	60724019	14	-	28162770	OCIAML2	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	-1.1038474945705383	[18]	[48]	-6	hSpCas9	negative selection	12266981
60723858	60723881	14	-	28162770	OCIAML2	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-3.680083190871111	[73]	[31]	-9	hSpCas9	negative selection	12266982
60723706	60723729	14	-	28162770	OCIAML2	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	-0.5637392296336428	[11]	[44]	-4	hSpCas9	negative selection	12266983
60723582	60723605	14	+	28162770	OCIAML2	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	0.03187051528702217	[41]	[237]	0	hSpCas9	negative selection	12266984
60723540	60723563	14	+	28162770	OCIAML2	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	-0.02132242387857125	[38]	[212]	0	hSpCas9	negative selection	12266985
60723519	60723542	14	+	28162770	OCIAML2	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	-0.09211820198843146	[4]	[25]	-1	hSpCas9	negative selection	12266986
60723495	60723518	14	-	28162770	OCIAML2	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	0.03838382224569625	[12]	[73]	0	hSpCas9	negative selection	12266987
60723966	60723989	14	-	28162770	OCIAML3	viability	GGAGGCGCACCGAGAAGTGGCGG	SIX4	ENSG00000100625	0.5986374376182325	[20]	[95]	5	hSpCas9	negative selection	12436344
60723250	60723273	14	-	28162770	OCIAML3	viability	GCAACTGGTTCAAGAACCGCCGG	SIX4	ENSG00000100625	-0.7036321314986616	[40]	[75]	-5	hSpCas9	negative selection	12436345
60724032	60724055	14	-	28162770	OCIAML3	viability	CGGGCAGATCGCAAGTGCGGCGG	SIX4	ENSG00000100625	-1.08704765160428	[37]	[53]	-7	hSpCas9	negative selection	12436346
60723996	60724019	14	-	28162770	OCIAML3	viability	GAATGGGATGGAAAGCGCCTCGG	SIX4	ENSG00000100625	1.1303579170624092	[22]	[151]	8	hSpCas9	negative selection	12436347
60723858	60723881	14	-	28162770	OCIAML3	viability	GAGCGGAGAGGAAGGGGCAGTGG	SIX4	ENSG00000100625	-3.969047071671088	[82]	[15]	-9	hSpCas9	negative selection	12436348
60723706	60723729	14	-	28162770	OCIAML3	viability	TGTGCGAGGCACTGCAGCAGGGG	SIX4	ENSG00000100625	-4.009045139603007	[15]	[2]	-9	hSpCas9	negative selection	12436349
60723582	60723605	14	+	28162770	OCIAML3	viability	GCTCGGGGTAGATGCCCTGGTGG	SIX4	ENSG00000100625	1.3644132559244375	[43]	[341]	9	hSpCas9	negative selection	12436350
60723540	60723563	14	+	28162770	OCIAML3	viability	GGTTGGCCGACTCGAAGCTGTGG	SIX4	ENSG00000100625	-0.4407613800284811	[57]	[128]	-3	hSpCas9	negative selection	12436351
60723519	60723542	14	+	28162770	OCIAML3	viability	AGAGCTGCTGCAGCAGCGGGTGG	SIX4	ENSG00000100625	0.9909548603969931	[11]	[71]	8	hSpCas9	negative selection	12436352
60723495	60723518	14	-	28162770	OCIAML3	viability	GTACAAGGCGCGCTACACCGAGG	SIX4	ENSG00000100625	1.194488254482125	[10]	[75]	8	hSpCas9	negative selection	12436353