Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:55234
• Symbol:Smu1
• Description:SMU1 DNA replication regulator and spliceosomal factor

DataSource: http://genomecrispr.dkfz.de/#!/results/Smu1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
33053146	33053169	9	-	26472758	Jiyoye	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-6.222181238573737	[98]	[0]	-9	hSpCas9	negative selection	152480
33071830	33071853	9	+	26472758	Jiyoye	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-1.782649177374144	[72]	[15]	-8	hSpCas9	negative selection	152481
33056945	33056968	9	-	26472758	Jiyoye	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-3.9851420412728866	[209]	[9]	-9	hSpCas9	negative selection	152482
33053229	33053252	9	-	26472758	Jiyoye	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-2.9713362417478564	[51]	[4]	-9	hSpCas9	negative selection	152483
33060563	33060586	9	-	26472758	Jiyoye	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-4.825033898190782	[638]	[16]	-9	hSpCas9	negative selection	152484
33056110	33056133	9	+	26472758	Jiyoye	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-4.1067040211538	[296]	[12]	-9	hSpCas9	negative selection	152485
33053122	33053145	9	-	26472758	Jiyoye	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-4.3553253047674705	[189]	[6]	-9	hSpCas9	negative selection	152486
33073709	33073732	9	-	26472758	Jiyoye	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-5.265249960465622	[50]	[0]	-9	hSpCas9	negative selection	152487
33056195	33056218	9	-	26472758	Jiyoye	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	152488
33053213	33053236	9	+	26472758	Jiyoye	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-3.183939346196878	[469]	[38]	-9	hSpCas9	negative selection	152489
33053146	33053169	9	-	26472758	KBM7	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-4.567332612082872	[308,271]	[0,9]	-9	hSpCas9	negative selection	343598
33071830	33071853	9	+	26472758	KBM7	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-1.5557355588238837	[706,775]	[86,148]	-8	hSpCas9	negative selection	343599
33056945	33056968	9	-	26472758	KBM7	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-2.437764272459173	[717,460]	[82,20]	-9	hSpCas9	negative selection	343600
33053229	33053252	9	-	26472758	KBM7	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-0.9459760692478476	[252,118]	[44,42]	-6	hSpCas9	negative selection	343601
33060563	33060586	9	-	26472758	KBM7	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-0.9854533825694973	[2383,1941]	[476,540]	-6	hSpCas9	negative selection	343602
33056110	33056133	9	+	26472758	KBM7	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-1.4651503520359344	[890,893]	[128,173]	-8	hSpCas9	negative selection	343603
33053122	33053145	9	-	26472758	KBM7	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-1.4743032032619316	[510,490]	[27,135]	-8	hSpCas9	negative selection	343604
33073709	33073732	9	-	26472758	KBM7	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-3.0459766002583777	[444,464]	[14,35]	-9	hSpCas9	negative selection	343605
33056195	33056218	9	-	26472758	KBM7	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-1.4931377516554685	[0,9]	[0,0]	-8	hSpCas9	negative selection	343606
33053213	33053236	9	+	26472758	KBM7	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-1.8060303041275951	[1782,1331]	[181,229]	-8	hSpCas9	negative selection	343607
33053146	33053169	9	-	26472758	Raji	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-4.699971386684005	[111]	[0]	-9	hSpCas9	negative selection	534716
33071830	33071853	9	+	26472758	Raji	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-2.179964327803618	[370]	[18]	-8	hSpCas9	negative selection	534717
33056945	33056968	9	-	26472758	Raji	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-5.092288809462765	[293]	[1]	-9	hSpCas9	negative selection	534718
33053229	33053252	9	-	26472758	Raji	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-4.082441023506418	[72]	[0]	-9	hSpCas9	negative selection	534719
33060563	33060586	9	-	26472758	Raji	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-2.5863146048884373	[853]	[32]	-9	hSpCas9	negative selection	534720
33056110	33056133	9	+	26472758	Raji	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-2.1060978320554526	[537]	[28]	-8	hSpCas9	negative selection	534721
33053122	33053145	9	-	26472758	Raji	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-2.2525124097127835	[307]	[14]	-9	hSpCas9	negative selection	534722
33073709	33073732	9	-	26472758	Raji	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-5.462472072957349	[189]	[0]	-9	hSpCas9	negative selection	534723
33056195	33056218	9	-	26472758	Raji	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	534724
33053213	33053236	9	+	26472758	Raji	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-3.1562769043345824	[921]	[23]	-9	hSpCas9	negative selection	534725
33053146	33053169	9	-	26472758	K562	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-7.462940404414435	[208]	[0]	-9	hSpCas9	negative selection	725834
33071830	33071853	9	+	26472758	K562	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-3.1490626282459493	[619]	[58]	-8	hSpCas9	negative selection	725835
33056945	33056968	9	-	26472758	K562	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-3.85097829512611	[546]	[31]	-9	hSpCas9	negative selection	725836
33053229	33053252	9	-	26472758	K562	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-1.125692900730881	[136]	[52]	-6	hSpCas9	negative selection	725837
33060563	33060586	9	-	26472758	K562	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-4.035689191526288	[1903]	[97]	-9	hSpCas9	negative selection	725838
33056110	33056133	9	+	26472758	K562	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-4.396227905632387	[897]	[35]	-9	hSpCas9	negative selection	725839
33053122	33053145	9	-	26472758	K562	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-2.1120665892572843	[506]	[98]	-7	hSpCas9	negative selection	725840
33073709	33073732	9	-	26472758	K562	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-8.31017012401119	[375]	[0]	-9	hSpCas9	negative selection	725841
33056195	33056218	9	-	26472758	K562	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	4.1023997227940185	[1]	[28]	9	hSpCas9	negative selection	725842
33053213	33053236	9	+	26472758	K562	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-2.826858685842954	[974]	[115]	-8	hSpCas9	negative selection	725843
33047373	33047396	9	+	26627737	DLD1	viability	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	0.1414499723893663	[527]	[134,269,149]	1	hSpCas9	negative selection	842651
33047373	33047396	9	+	26627737	GBM cells	viability after 5 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	-0.13585154327499097	[251]	[156,88]	-2	hSpCas9	negative selection	924966
33047373	33047396	9	+	26627737	GBM cells	viability after 13 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	-0.12667940671951458	[251]	[186,74]	-1	hSpCas9	negative selection	1007281
33047373	33047396	9	+	26627737	GBM cells	viability after 21 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	-0.04224637255897705	[251]	[133,131]	0	hSpCas9	negative selection	1089596
33047373	33047396	9	+	26627737	RPE1	viability after 9 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	0.6391787048664539	[534]	[190,350]	4	hSpCas9	negative selection	1171911
33047373	33047396	9	+	26627737	RPE1	viability after 12 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	-0.2569621686065795	[534]	[146,91]	-2	hSpCas9	negative selection	1254226
33047373	33047396	9	+	26627737	RPE1	viability after 15 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	-0.42377990536262533	[534]	[122,102]	-3	hSpCas9	negative selection	1336541
33047373	33047396	9	+	26627737	RPE1	viability after 18 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	-1.1719117744584366	[534]	[80,45]	-6	hSpCas9	negative selection	1418856
33047373	33047396	9	+	26627737	HeLa	viability after 8 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	1.0692880948319639	[218]	[281,195,143]	7	hSpCas9	negative selection	1501171
33047373	33047396	9	+	26627737	HeLa	viability after 12 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	0.9873139107636062	[218]	[158,166,212]	7	hSpCas9	negative selection	1583486
33047373	33047396	9	+	26627737	HeLa	viability after 15 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	0.7181727166138513	[218]	[38,175,232]	5	hSpCas9	negative selection	1665801
33047373	33047396	9	+	26627737	HeLa	viability after 18 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	0.7072403025833888	[218]	[22,146,232]	5	hSpCas9	negative selection	1748116
33047373	33047396	9	+	26627737	HCT116	viability after 6 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	-0.42513432512960614	[747]	[220,13]	-2	hSpCas9	negative selection	1830431
33047373	33047396	9	+	26627737	HCT116	viability after 8 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	0.018519561686389602	[267]	[165,129,152]	0	hSpCas9	negative selection	1912746
33047373	33047396	9	+	26627737	HCT116	viability after 9 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	-0.2543918223716968	[747]	[291,68]	-2	hSpCas9	negative selection	1995061
33047373	33047396	9	+	26627737	HCT116	viability after 12 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	0.41985304333909773	[267]	[224,186,149]	4	hSpCas9	negative selection	2077376
33047373	33047396	9	+	26627737	HCT116	viability after 15 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	-0.45058597242119414	[267]	[150,116,74]	-5	hSpCas9	negative selection	2159691
33047373	33047396	9	+	26627737	HCT116	viability after 18 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	0.2411364352753655	[267]	[205,74,184]	2	hSpCas9	negative selection	2242006
33064866	33064889	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCCCAGTTACTTGG	SMU1	ENSG00000122692	-1.4499740674906352	[80,484]	[11,33]	-8	dCas9-VP64	positive selection	2386050
33063267	33063290	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAAAATTGCTTGAACCCGGG	SMU1	ENSG00000122692	3.06787684374975	[49,8]	[78,27]	8	dCas9-VP64	positive selection	2415344
33069756	33069779	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGTGCCATTGCACTCCAGCCGGG	SMU1	ENSG00000122692	-0.5971814264096912	[233,130]	[36,14]	-3	dCas9-VP64	positive selection	2447002
33064866	33064889	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCCCAGTTACTTGG	SMU1	ENSG00000122692	0.5129370309291919	[140,116]	[29,88]	4	dCas9-VP64	positive selection	2481305
33063267	33063290	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAAAATTGCTTGAACCCGGG	SMU1	ENSG00000122692	0.014675341320169899	[37,72]	[27,8]	0	dCas9-VP64	positive selection	2510599
33069756	33069779	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGTGCCATTGCACTCCAGCCGGG	SMU1	ENSG00000122692	0.14726127288975888	[140,101]	[59,28]	1	dCas9-VP64	positive selection	2542257
33048172	33048195	9	+	27260157	DLD1	viability	ACAGTAGATCCATTCACCACGGG	SMU1	ENSG00000122692	-2.57803892788732	[]	[]	-9	hSpCas9	negative selection	2573911
33056906	33056929	9	-	27260157	DLD1	viability	TTTGAGAGGGCACACAGTAAGGG	SMU1	ENSG00000122692	-4.93360583637024	[]	[]	-9	hSpCas9	negative selection	2576925
33062166	33062189	9	-	27260157	DLD1	viability	TTTCCTCATAGGCACTGAAGTGG	SMU1	ENSG00000122692	-1.92422053508072	[]	[]	-8	hSpCas9	negative selection	2579194
33056110	33056133	9	+	27260157	DLD1	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-2.61355388876238	[]	[]	-9	hSpCas9	negative selection	2586794
33068831	33068854	9	+	27260157	DLD1	viability	AGCAATGCCATGAGACGAGATGG	SMU1	ENSG00000122692	-2.67165573591341	[]	[]	-9	hSpCas9	negative selection	2587570
33053163	33053186	9	+	27260157	DLD1	viability	TTGCACACCACAAAGTGCTCAGG	SMU1	ENSG00000122692	-0.175546100174973	[]	[]	-1	hSpCas9	negative selection	2605816
33068859	33068882	9	-	27260157	DLD1	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-3.45350196600292	[]	[]	-9	hSpCas9	negative selection	2609685
33056844	33056867	9	+	27260157	DLD1	viability	TCTGGTCAAAAGAAGCACTAAGG	SMU1	ENSG00000122692	-3.33674811144832	[]	[]	-9	hSpCas9	negative selection	2610325
33071804	33071827	9	+	27260157	DLD1	viability	GTTTGTTTTAACATGATCATGGG	SMU1	ENSG00000122692	-0.157605739442658	[]	[]	-1	hSpCas9	negative selection	2610481
33062109	33062132	9	+	27260157	DLD1	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-4.76983571815543	[]	[]	-9	hSpCas9	negative selection	2610529
33053164	33053187	9	+	27260157	DLD1	viability	TGCACACCACAAAGTGCTCAGGG	SMU1	ENSG00000122692	-1.00696169819152	[]	[]	-7	hSpCas9	negative selection	2611731
33047379	33047402	9	-	27260157	DLD1	viability	CATGTTCCAGGTGCACGAGAAGG	SMU1	ENSG00000122692	-2.74024805313851	[]	[]	-9	hSpCas9	negative selection	2612119
33048171	33048194	9	+	27260157	DLD1	viability	CACAGTAGATCCATTCACCACGG	SMU1	ENSG00000122692	-3.108820100275	[]	[]	-9	hSpCas9	negative selection	2616831
33062053	33062076	9	+	27260157	DLD1	viability	ATATGCCTGCTCAGTTGTGTAGG	SMU1	ENSG00000122692	-2.85729526731987	[]	[]	-9	hSpCas9	negative selection	2621796
33068860	33068883	9	+	27260157	DLD1	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-3.24624066254278	[]	[]	-9	hSpCas9	negative selection	2623516
33056878	33056901	9	+	27260157	DLD1	viability	ATCCTTAGAAAAGCTTAGACAGG	SMU1	ENSG00000122692	-2.31111648931722	[]	[]	-9	hSpCas9	negative selection	2623559
33076602	33076625	9	+	27260157	DLD1	viability	TCGACATAGCCGTATCTCTCCGG	SMU1	ENSG00000122692	-3.17954909312182	[]	[]	-9	hSpCas9	negative selection	2644827
33062113	33062136	9	-	27260157	DLD1	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.72637982478422	[]	[]	-8	hSpCas9	negative selection	2645693
33056190	33056213	9	+	27260157	DLD1	viability	AATGGCCACGAAATTCCTTCAGG	SMU1	ENSG00000122692	-0.0392102159667179	[]	[]	0	hSpCas9	negative selection	2646279
33068834	33068857	9	+	27260157	DLD1	viability	AATGCCATGAGACGAGATGGAGG	SMU1	ENSG00000122692	-3.46792804312362	[]	[]	-9	hSpCas9	negative selection	2648800
33048172	33048195	9	+	27260157	HT1080	viability	ACAGTAGATCCATTCACCACGGG	SMU1	ENSG00000122692	-1.85783761419021	[]	[]	-9	hSpCas9	negative selection	2650041
33056906	33056929	9	-	27260157	HT1080	viability	TTTGAGAGGGCACACAGTAAGGG	SMU1	ENSG00000122692	-2.67012355216956	[]	[]	-9	hSpCas9	negative selection	2653055
33062166	33062189	9	-	27260157	HT1080	viability	TTTCCTCATAGGCACTGAAGTGG	SMU1	ENSG00000122692	-4.28967146057128	[]	[]	-9	hSpCas9	negative selection	2655324
33056110	33056133	9	+	27260157	HT1080	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-2.88665168191365	[]	[]	-9	hSpCas9	negative selection	2662924
33068831	33068854	9	+	27260157	HT1080	viability	AGCAATGCCATGAGACGAGATGG	SMU1	ENSG00000122692	-1.12608311640129	[]	[]	-8	hSpCas9	negative selection	2663700
33053163	33053186	9	+	27260157	HT1080	viability	TTGCACACCACAAAGTGCTCAGG	SMU1	ENSG00000122692	-1.07940684925138	[]	[]	-8	hSpCas9	negative selection	2681946
33068859	33068882	9	-	27260157	HT1080	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-4.32300992977918	[]	[]	-9	hSpCas9	negative selection	2685815
33056844	33056867	9	+	27260157	HT1080	viability	TCTGGTCAAAAGAAGCACTAAGG	SMU1	ENSG00000122692	-3.8948321380514	[]	[]	-9	hSpCas9	negative selection	2686455
33071804	33071827	9	+	27260157	HT1080	viability	GTTTGTTTTAACATGATCATGGG	SMU1	ENSG00000122692	-1.45494367910912	[]	[]	-9	hSpCas9	negative selection	2686611
33062109	33062132	9	+	27260157	HT1080	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-3.87338202556272	[]	[]	-9	hSpCas9	negative selection	2686659
33053164	33053187	9	+	27260157	HT1080	viability	TGCACACCACAAAGTGCTCAGGG	SMU1	ENSG00000122692	-0.677477441487948	[]	[]	-8	hSpCas9	negative selection	2687861
33047379	33047402	9	-	27260157	HT1080	viability	CATGTTCCAGGTGCACGAGAAGG	SMU1	ENSG00000122692	-3.25454193220684	[]	[]	-9	hSpCas9	negative selection	2688249
33048171	33048194	9	+	27260157	HT1080	viability	CACAGTAGATCCATTCACCACGG	SMU1	ENSG00000122692	-2.73452627589742	[]	[]	-9	hSpCas9	negative selection	2692961
33062053	33062076	9	+	27260157	HT1080	viability	ATATGCCTGCTCAGTTGTGTAGG	SMU1	ENSG00000122692	-3.99936309727698	[]	[]	-9	hSpCas9	negative selection	2697926
33068860	33068883	9	+	27260157	HT1080	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.58767507043026	[]	[]	-9	hSpCas9	negative selection	2699646
33056878	33056901	9	+	27260157	HT1080	viability	ATCCTTAGAAAAGCTTAGACAGG	SMU1	ENSG00000122692	-3.78840317294336	[]	[]	-9	hSpCas9	negative selection	2699689
33076602	33076625	9	+	27260157	HT1080	viability	TCGACATAGCCGTATCTCTCCGG	SMU1	ENSG00000122692	-1.67670239521634	[]	[]	-9	hSpCas9	negative selection	2720957
33062113	33062136	9	-	27260157	HT1080	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.46932539155557	[]	[]	-9	hSpCas9	negative selection	2721823
33056190	33056213	9	+	27260157	HT1080	viability	AATGGCCACGAAATTCCTTCAGG	SMU1	ENSG00000122692	0.954089340420831	[]	[]	7	hSpCas9	negative selection	2722409
33068834	33068857	9	+	27260157	HT1080	viability	AATGCCATGAGACGAGATGGAGG	SMU1	ENSG00000122692	-3.39402858505518	[]	[]	-9	hSpCas9	negative selection	2724930
33048172	33048195	9	+	27260157	MKN45	viability	ACAGTAGATCCATTCACCACGGG	SMU1	ENSG00000122692	-3.35805900339421	[]	[]	-9	hSpCas9	negative selection	2726171
33056906	33056929	9	-	27260157	MKN45	viability	TTTGAGAGGGCACACAGTAAGGG	SMU1	ENSG00000122692	-2.3235045646016	[]	[]	-9	hSpCas9	negative selection	2729185
33062166	33062189	9	-	27260157	MKN45	viability	TTTCCTCATAGGCACTGAAGTGG	SMU1	ENSG00000122692	-3.14719451540271	[]	[]	-9	hSpCas9	negative selection	2731454
33056110	33056133	9	+	27260157	MKN45	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-1.40845053196383	[]	[]	-8	hSpCas9	negative selection	2739054
33068831	33068854	9	+	27260157	MKN45	viability	AGCAATGCCATGAGACGAGATGG	SMU1	ENSG00000122692	-2.34889445286392	[]	[]	-9	hSpCas9	negative selection	2739830
33053163	33053186	9	+	27260157	MKN45	viability	TTGCACACCACAAAGTGCTCAGG	SMU1	ENSG00000122692	-1.16410836669989	[]	[]	-8	hSpCas9	negative selection	2758076
33068859	33068882	9	-	27260157	MKN45	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-3.25738519740522	[]	[]	-9	hSpCas9	negative selection	2761945
33056844	33056867	9	+	27260157	MKN45	viability	TCTGGTCAAAAGAAGCACTAAGG	SMU1	ENSG00000122692	-3.15393356058348	[]	[]	-9	hSpCas9	negative selection	2762585
33071804	33071827	9	+	27260157	MKN45	viability	GTTTGTTTTAACATGATCATGGG	SMU1	ENSG00000122692	-0.113068469738004	[]	[]	0	hSpCas9	negative selection	2762741
33062109	33062132	9	+	27260157	MKN45	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-4.66313842923185	[]	[]	-9	hSpCas9	negative selection	2762789
33053164	33053187	9	+	27260157	MKN45	viability	TGCACACCACAAAGTGCTCAGGG	SMU1	ENSG00000122692	-0.510155541231348	[]	[]	-6	hSpCas9	negative selection	2763991
33047379	33047402	9	-	27260157	MKN45	viability	CATGTTCCAGGTGCACGAGAAGG	SMU1	ENSG00000122692	-3.10941745002836	[]	[]	-9	hSpCas9	negative selection	2764379
33048171	33048194	9	+	27260157	MKN45	viability	CACAGTAGATCCATTCACCACGG	SMU1	ENSG00000122692	-3.22891563316932	[]	[]	-9	hSpCas9	negative selection	2769091
33062053	33062076	9	+	27260157	MKN45	viability	ATATGCCTGCTCAGTTGTGTAGG	SMU1	ENSG00000122692	-1.8035130626175	[]	[]	-9	hSpCas9	negative selection	2774056
33068860	33068883	9	+	27260157	MKN45	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.40796477891115	[]	[]	-8	hSpCas9	negative selection	2775776
33056878	33056901	9	+	27260157	MKN45	viability	ATCCTTAGAAAAGCTTAGACAGG	SMU1	ENSG00000122692	-1.46813966426398	[]	[]	-8	hSpCas9	negative selection	2775819
33076602	33076625	9	+	27260157	MKN45	viability	TCGACATAGCCGTATCTCTCCGG	SMU1	ENSG00000122692	-3.76687225506758	[]	[]	-9	hSpCas9	negative selection	2797087
33062113	33062136	9	-	27260157	MKN45	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.51723975113938	[]	[]	-8	hSpCas9	negative selection	2797953
33056190	33056213	9	+	27260157	MKN45	viability	AATGGCCACGAAATTCCTTCAGG	SMU1	ENSG00000122692	-0.236032763908389	[]	[]	-1	hSpCas9	negative selection	2798539
33068834	33068857	9	+	27260157	MKN45	viability	AATGCCATGAGACGAGATGGAGG	SMU1	ENSG00000122692	-3.18917748261078	[]	[]	-9	hSpCas9	negative selection	2801060
33048172	33048195	9	+	27260157	RKO	viability	ACAGTAGATCCATTCACCACGGG	SMU1	ENSG00000122692	-3.87143600485917	[]	[]	-9	hSpCas9	negative selection	2802301
33056906	33056929	9	-	27260157	RKO	viability	TTTGAGAGGGCACACAGTAAGGG	SMU1	ENSG00000122692	-3.1270935341378	[]	[]	-9	hSpCas9	negative selection	2805315
33062166	33062189	9	-	27260157	RKO	viability	TTTCCTCATAGGCACTGAAGTGG	SMU1	ENSG00000122692	-3.42846020049453	[]	[]	-9	hSpCas9	negative selection	2807584
33056110	33056133	9	+	27260157	RKO	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-2.57916107716289	[]	[]	-9	hSpCas9	negative selection	2815184
33068831	33068854	9	+	27260157	RKO	viability	AGCAATGCCATGAGACGAGATGG	SMU1	ENSG00000122692	-2.07196518701269	[]	[]	-9	hSpCas9	negative selection	2815960
33053163	33053186	9	+	27260157	RKO	viability	TTGCACACCACAAAGTGCTCAGG	SMU1	ENSG00000122692	-1.62400870079082	[]	[]	-9	hSpCas9	negative selection	2834206
33068859	33068882	9	-	27260157	RKO	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-3.63621428093677	[]	[]	-9	hSpCas9	negative selection	2838075
33056844	33056867	9	+	27260157	RKO	viability	TCTGGTCAAAAGAAGCACTAAGG	SMU1	ENSG00000122692	-3.73899543049237	[]	[]	-9	hSpCas9	negative selection	2838715
33071804	33071827	9	+	27260157	RKO	viability	GTTTGTTTTAACATGATCATGGG	SMU1	ENSG00000122692	-1.81254913936244	[]	[]	-9	hSpCas9	negative selection	2838871
33062109	33062132	9	+	27260157	RKO	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.15074052624335	[]	[]	-8	hSpCas9	negative selection	2838919
33053164	33053187	9	+	27260157	RKO	viability	TGCACACCACAAAGTGCTCAGGG	SMU1	ENSG00000122692	-1.66663651653303	[]	[]	-9	hSpCas9	negative selection	2840121
33047379	33047402	9	-	27260157	RKO	viability	CATGTTCCAGGTGCACGAGAAGG	SMU1	ENSG00000122692	-2.12903507327568	[]	[]	-9	hSpCas9	negative selection	2840509
33048171	33048194	9	+	27260157	RKO	viability	CACAGTAGATCCATTCACCACGG	SMU1	ENSG00000122692	-3.00077469762772	[]	[]	-9	hSpCas9	negative selection	2845221
33062053	33062076	9	+	27260157	RKO	viability	ATATGCCTGCTCAGTTGTGTAGG	SMU1	ENSG00000122692	-1.9364740849796	[]	[]	-9	hSpCas9	negative selection	2850186
33068860	33068883	9	+	27260157	RKO	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-2.08945238982176	[]	[]	-9	hSpCas9	negative selection	2851906
33056878	33056901	9	+	27260157	RKO	viability	ATCCTTAGAAAAGCTTAGACAGG	SMU1	ENSG00000122692	-2.26713065778828	[]	[]	-9	hSpCas9	negative selection	2851949
33076602	33076625	9	+	27260157	RKO	viability	TCGACATAGCCGTATCTCTCCGG	SMU1	ENSG00000122692	-1.9757691524645	[]	[]	-9	hSpCas9	negative selection	2873217
33062113	33062136	9	-	27260157	RKO	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.48011271584442	[]	[]	-8	hSpCas9	negative selection	2874083
33056190	33056213	9	+	27260157	RKO	viability	AATGGCCACGAAATTCCTTCAGG	SMU1	ENSG00000122692	-0.843303374753572	[]	[]	-7	hSpCas9	negative selection	2874669
33068834	33068857	9	+	27260157	RKO	viability	AATGCCATGAGACGAGATGGAGG	SMU1	ENSG00000122692	-3.42289647120135	[]	[]	-9	hSpCas9	negative selection	2877190
33048172	33048195	9	+	27260157	SF268	viability	ACAGTAGATCCATTCACCACGGG	SMU1	ENSG00000122692	-3.15603416240582	[]	[]	-9	hSpCas9	negative selection	2878431
33056906	33056929	9	-	27260157	SF268	viability	TTTGAGAGGGCACACAGTAAGGG	SMU1	ENSG00000122692	-3.86595841499306	[]	[]	-9	hSpCas9	negative selection	2881445
33062166	33062189	9	-	27260157	SF268	viability	TTTCCTCATAGGCACTGAAGTGG	SMU1	ENSG00000122692	-4.32371059667898	[]	[]	-9	hSpCas9	negative selection	2883714
33056110	33056133	9	+	27260157	SF268	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-3.59616765158088	[]	[]	-9	hSpCas9	negative selection	2891314
33068831	33068854	9	+	27260157	SF268	viability	AGCAATGCCATGAGACGAGATGG	SMU1	ENSG00000122692	-4.01625935631393	[]	[]	-9	hSpCas9	negative selection	2892090
33053163	33053186	9	+	27260157	SF268	viability	TTGCACACCACAAAGTGCTCAGG	SMU1	ENSG00000122692	-2.61211836174603	[]	[]	-9	hSpCas9	negative selection	2910336
33068859	33068882	9	-	27260157	SF268	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-3.01678481040994	[]	[]	-9	hSpCas9	negative selection	2914205
33056844	33056867	9	+	27260157	SF268	viability	TCTGGTCAAAAGAAGCACTAAGG	SMU1	ENSG00000122692	-4.05102018451137	[]	[]	-9	hSpCas9	negative selection	2914845
33071804	33071827	9	+	27260157	SF268	viability	GTTTGTTTTAACATGATCATGGG	SMU1	ENSG00000122692	0.381526379004331	[]	[]	4	hSpCas9	negative selection	2915001
33062109	33062132	9	+	27260157	SF268	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-6.70805338511327	[]	[]	-10	hSpCas9	negative selection	2915049
33053164	33053187	9	+	27260157	SF268	viability	TGCACACCACAAAGTGCTCAGGG	SMU1	ENSG00000122692	-1.1749282521342	[]	[]	-7	hSpCas9	negative selection	2916251
33047379	33047402	9	-	27260157	SF268	viability	CATGTTCCAGGTGCACGAGAAGG	SMU1	ENSG00000122692	-3.4395686793802	[]	[]	-9	hSpCas9	negative selection	2916639
33048171	33048194	9	+	27260157	SF268	viability	CACAGTAGATCCATTCACCACGG	SMU1	ENSG00000122692	-3.46098243127486	[]	[]	-9	hSpCas9	negative selection	2921351
33062053	33062076	9	+	27260157	SF268	viability	ATATGCCTGCTCAGTTGTGTAGG	SMU1	ENSG00000122692	-4.9963001575546	[]	[]	-9	hSpCas9	negative selection	2926316
33068860	33068883	9	+	27260157	SF268	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-3.5118182208466	[]	[]	-9	hSpCas9	negative selection	2928036
33056878	33056901	9	+	27260157	SF268	viability	ATCCTTAGAAAAGCTTAGACAGG	SMU1	ENSG00000122692	-3.60626572250433	[]	[]	-9	hSpCas9	negative selection	2928079
33076602	33076625	9	+	27260157	SF268	viability	TCGACATAGCCGTATCTCTCCGG	SMU1	ENSG00000122692	-3.02074898255475	[]	[]	-9	hSpCas9	negative selection	2949347
33062113	33062136	9	-	27260157	SF268	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.57163665616621	[]	[]	-8	hSpCas9	negative selection	2950213
33056190	33056213	9	+	27260157	SF268	viability	AATGGCCACGAAATTCCTTCAGG	SMU1	ENSG00000122692	0.0040716848231705	[]	[]	0	hSpCas9	negative selection	2950799
33068834	33068857	9	+	27260157	SF268	viability	AATGCCATGAGACGAGATGGAGG	SMU1	ENSG00000122692	-4.63631547920536	[]	[]	-9	hSpCas9	negative selection	2953320
33073587	33073610	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	0.5531028801551171	[2,2]	[3,3]	9	hSpCas9	positive selection	3022319
33073650	33073673	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGCAACACAGTATCCCAATGG	SMU1	ENSG00000122692	0.4214732894180354	[2,3]	[3,3]	8	hSpCas9	positive selection	3022320
33073779	33073802	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAAGTACTGCATAATAAGGCGG	SMU1	ENSG00000122692	0.3409370538957209	[1,2]	[3,1]	7	hSpCas9	positive selection	3022321
33073672	33073695	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTGTGGCTGACATTAACAGTGG	SMU1	ENSG00000122692	0.023953413159644263	[2,3]	[4,1]	0	hSpCas9	positive selection	3022322
33073587	33073610	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.5692081010606141	[2,2]	[1,0]	-7	hSpCas9	positive selection	3090177
33073650	33073673	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGCAACACAGTATCCCAATGG	SMU1	ENSG00000122692	-0.5045667306404336	[2,2]	[2,0]	-7	hSpCas9	positive selection	3090178
33073779	33073802	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAAGTACTGCATAATAAGGCGG	SMU1	ENSG00000122692	0.14594166766358319	[1,1]	[2,0]	2	hSpCas9	positive selection	3090179
33073672	33073695	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTGTGGCTGACATTAACAGTGG	SMU1	ENSG00000122692	-0.16558523748695095	[2,2]	[3,0]	-2	hSpCas9	positive selection	3090180
33062109	33062132		+	24336571	A375	resistance to PLX after 7 days	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-0.18578618100470634	[3,4]	[3,3]	-6	hSpCas9	positive selection	3146262
33068921	33068944		-	24336571	A375	resistance to PLX after 7 days	CTTTTTCAGGCATACCCAGATGG	SMU1	ENSG00000122692	-0.08327692640920814	[10,9]	[9,9]	-2	hSpCas9	positive selection	3146263
33062166	33062189		-	24336571	A375	resistance to PLX after 7 days	TTTCCTCATAGGCACTGAAGTGG	SMU1	ENSG00000122692	0.10312572066232462	[2,3]	[2,3]	3	hSpCas9	positive selection	3146265
33062109	33062132		+	24336571	A375	resistance to PLX after 14 days	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	0.554166786893578	[3,2]	[1,1]	5	hSpCas9	positive selection	3204055
33068921	33068944		-	24336571	A375	resistance to PLX after 14 days	CTTTTTCAGGCATACCCAGATGG	SMU1	ENSG00000122692	-0.06133405216799076	[8,9]	[2,4]	0	hSpCas9	positive selection	3204056
33062166	33062189		-	24336571	A375	resistance to PLX after 14 days	TTTCCTCATAGGCACTGAAGTGG	SMU1	ENSG00000122692	0.0225971348462346	[4,2]	[1,1]	0	hSpCas9	positive selection	3204058
33062109	33062132		+	24336571	A375	viability after 7 days	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.0850007673252908	[9]	[3,4]	-9	hSpCas9	negative selection	3261848
33068921	33068944		-	24336571	A375	viability after 7 days	CTTTTTCAGGCATACCCAGATGG	SMU1	ENSG00000122692	-0.12032243255321898	[11]	[10,9]	-2	hSpCas9	negative selection	3261849
33062166	33062189		-	24336571	A375	viability after 7 days	TTTCCTCATAGGCACTGAAGTGG	SMU1	ENSG00000122692	-1.1932127586526797	[8]	[2,3]	-9	hSpCas9	negative selection	3261851
33062109	33062132		+	24336571	A375	viability after 14 days	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.349264761622458	[9]	[3,2]	-9	hSpCas9	negative selection	3319641
33068921	33068944		-	24336571	A375	viability after 14 days	CTTTTTCAGGCATACCCAGATGG	SMU1	ENSG00000122692	-0.16393155672192802	[11]	[8,9]	-2	hSpCas9	negative selection	3319642
33062166	33062189		-	24336571	A375	viability after 14 days	TTTCCTCATAGGCACTGAAGTGG	SMU1	ENSG00000122692	-0.996276456886779	[8]	[4,2]	-8	hSpCas9	negative selection	3319644
33062109	33062132	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	2.3031299010589596	[30,30]	[0,0]	8	hSpCas9	positive selection	3393977
33068859	33068882	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	2.2129320920873816	[32,32]	[0,0]	7	hSpCas9	positive selection	3393978
33062113	33062136	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	3.4499712893882313	[27,27]	[1,1]	9	hSpCas9	positive selection	3393979
33073586	33073609	9	+	26780180	HT29	viability (Avana library 4 designs)	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	6.58292656620072	[]	[]	9	hSpCas9	negative selection	3460907
33073649	33073672	9	+	26780180	HT29	viability (Avana library 4 designs)	CCTGCAACACAGTATCCCAATGG	SMU1	ENSG00000122692	5.53401281613752	[]	[]	9	hSpCas9	negative selection	3460908
33073778	33073801	9	+	26780180	HT29	viability (Avana library 4 designs)	TCAAGTACTGCATAATAAGGCGG	SMU1	ENSG00000122692	5.33129238849086	[]	[]	9	hSpCas9	negative selection	3460909
33073672	33073695	9	-	26780180	HT29	viability (Avana library 4 designs)	TTTGTGGCTGACATTAACAGTGG	SMU1	ENSG00000122692	5.34299681131567	[]	[]	9	hSpCas9	negative selection	3460910
33073672	33073695	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGTGGCTGACATTAACAGTGG	SMU1	ENSG00000122692	-17.95149182412	[]	[]	-9	hSpCas9	negative selection	3561506
33073778	33073801	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAAGTACTGCATAATAAGGCGG	SMU1	ENSG00000122692	-25.4452539570294	[]	[]	-9	hSpCas9	negative selection	3561507
33073649	33073672	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGCAACACAGTATCCCAATGG	SMU1	ENSG00000122692	-11.7194693772251	[]	[]	-8	hSpCas9	negative selection	3561508
33073586	33073609	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-14.3599283012511	[]	[]	-8	hSpCas9	negative selection	3561509
33073758	33073781	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAGGAGAACAGTTTACATCGG	SMU1	ENSG00000122692	-13.084278512871	[]	[]	-8	hSpCas9	negative selection	3561510
33073596	33073619	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGTTCATAGAGGTCAATGAGGG	SMU1	ENSG00000122692	-15.556725274265	[]	[]	-9	hSpCas9	negative selection	3561511
33073672	33073695	9	-	26780180	A375	viability (Avana lentiGuide)	TTTGTGGCTGACATTAACAGTGG	SMU1	ENSG00000122692	20.5667036490373	[]	[]	8	hSpCas9	negative selection	3670165
33073778	33073801	9	+	26780180	A375	viability (Avana lentiGuide)	TCAAGTACTGCATAATAAGGCGG	SMU1	ENSG00000122692	21.482461985005	[]	[]	9	hSpCas9	negative selection	3670166
33073649	33073672	9	+	26780180	A375	viability (Avana lentiGuide)	CCTGCAACACAGTATCCCAATGG	SMU1	ENSG00000122692	26.1829253086315	[]	[]	9	hSpCas9	negative selection	3670167
33073586	33073609	9	+	26780180	A375	viability (Avana lentiGuide)	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	13.8070449998797	[]	[]	7	hSpCas9	negative selection	3670168
33073758	33073781	9	-	26780180	A375	viability (Avana lentiGuide)	TGAAGGAGAACAGTTTACATCGG	SMU1	ENSG00000122692	31.11395764388	[]	[]	9	hSpCas9	negative selection	3670169
33073596	33073619	9	+	26780180	A375	viability (Avana lentiGuide)	CTGTTCATAGAGGTCAATGAGGG	SMU1	ENSG00000122692	22.7275136314936	[]	[]	9	hSpCas9	negative selection	3670170
33073672	33073695	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGTGGCTGACATTAACAGTGG	SMU1	ENSG00000122692	-2.1945799672956996	[6]	[0,0]	-9	hSpCas9	positive selection	3778772
33073778	33073801	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAAGTACTGCATAATAAGGCGG	SMU1	ENSG00000122692	-2.3407817311646437	[6]	[1,0]	-9	hSpCas9	positive selection	3778773
33073649	33073672	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGCAACACAGTATCCCAATGG	SMU1	ENSG00000122692	-1.3086504077368586	[6]	[2,0]	-9	hSpCas9	positive selection	3778774
33073586	33073609	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.6710986175542379	[5]	[3,2]	-7	hSpCas9	positive selection	3778775
33073758	33073781	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAGGAGAACAGTTTACATCGG	SMU1	ENSG00000122692	-0.7811785949859011	[6]	[3,2]	-8	hSpCas9	positive selection	3778776
33073596	33073619	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGTTCATAGAGGTCAATGAGGG	SMU1	ENSG00000122692	-1.4318661776557648	[5]	[2,0]	-9	hSpCas9	positive selection	3778777
33073672	33073695	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGTGGCTGACATTAACAGTGG	SMU1	ENSG00000122692	-0.34582502997684134	[7]	[2,6]	-4	hSpCas9	positive selection	3887379
33073778	33073801	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAAGTACTGCATAATAAGGCGG	SMU1	ENSG00000122692	-1.4430328938796972	[5]	[0,1]	-9	hSpCas9	positive selection	3887380
33073649	33073672	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGCAACACAGTATCCCAATGG	SMU1	ENSG00000122692	-0.9795418307579938	[6]	[0,3]	-8	hSpCas9	positive selection	3887381
33073586	33073609	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.5000536027829007	[6]	[3,3]	-6	hSpCas9	positive selection	3887382
33073758	33073781	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAGGAGAACAGTTTACATCGG	SMU1	ENSG00000122692	-1.011566689354812	[5]	[1,2]	-8	hSpCas9	positive selection	3887383
33073596	33073619	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGTTCATAGAGGTCAATGAGGG	SMU1	ENSG00000122692	-0.8721260379605283	[5]	[3,0]	-8	hSpCas9	positive selection	3887384
33062113	33062136	9	-	26780180	A375	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	0.822907685356692	[]	[]	3	hSpCas9	negative selection	3997472
33068860	33068883	9	+	26780180	A375	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	1.80886392402857	[]	[]	9	hSpCas9	negative selection	3997473
33073586	33073609	9	+	26780180	A375	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	2.39857157552742	[]	[]	9	hSpCas9	negative selection	3997474
33073595	33073618	9	-	26780180	A375	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	1.75854068035601	[]	[]	9	hSpCas9	negative selection	3997475
33068859	33068882	9	-	26780180	A375	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	2.12247508241604	[]	[]	9	hSpCas9	negative selection	3997476
33062109	33062132	9	+	26780180	A375	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	1.41407164153518	[]	[]	7	hSpCas9	negative selection	3997477
33062113	33062136	9	-	26780180	HT29	viability (GeCKOv2 library)	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	1.12922296887801	[]	[]	5	hSpCas9	negative selection	4105438
33068860	33068883	9	+	26780180	HT29	viability (GeCKOv2 library)	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	2.63577351957004	[]	[]	9	hSpCas9	negative selection	4105439
33073586	33073609	9	+	26780180	HT29	viability (GeCKOv2 library)	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	3.29747651808531	[]	[]	9	hSpCas9	negative selection	4105440
33073595	33073618	9	-	26780180	HT29	viability (GeCKOv2 library)	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	2.66433615201985	[]	[]	9	hSpCas9	negative selection	4105441
33068859	33068882	9	-	26780180	HT29	viability (GeCKOv2 library)	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	3.08395376251293	[]	[]	9	hSpCas9	negative selection	4105442
33062109	33062132	9	+	26780180	HT29	viability (GeCKOv2 library)	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	2.48019873029155	[]	[]	9	hSpCas9	negative selection	4105443
33062109	33062132	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-0.16783868712992422	[1]	[0,0]	-4	hSpCas9	positive selection	4172352
33068921	33068944	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTTTTCAGGCATACCCAGATGG	SMU1	ENSG00000122692	-0.018202072899364846	[3]	[2,1]	0	hSpCas9	positive selection	4172353
33062166	33062189	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTCCTCATAGGCACTGAAGTGG	SMU1	ENSG00000122692	-0.33711706432519173	[2]	[1,0]	-7	hSpCas9	positive selection	4172355
33062109	33062132	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-0.7642697842846456	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4236374
33068921	33068944	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTTTTCAGGCATACCCAGATGG	SMU1	ENSG00000122692	-0.5761233606166102	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4236375
33062166	33062189	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTCCTCATAGGCACTGAAGTGG	SMU1	ENSG00000122692	-0.7860166286707697	[2]	[0,0,0,0]	-9	hSpCas9	positive selection	4236377
33073595	33073618	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.05673698235074687	[3]	[2,2]	-1	hSpCas9	positive selection	4299468
33068860	33068883	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.4847314998435833	[3]	[1,1]	-8	hSpCas9	positive selection	4299469
33073586	33073609	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.7051430110874818	[3]	[2,0]	-9	hSpCas9	positive selection	4299470
33062109	33062132	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-0.756108736730432	[2]	[0,0]	-9	hSpCas9	positive selection	4363721
33068859	33068882	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.1133290225187082	[2]	[0,0]	-9	hSpCas9	positive selection	4363722
33062113	33062136	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.14651428005125233	[1]	[1,0]	-3	hSpCas9	positive selection	4363723
33060538	33060560	9	-	27760321	OCIAML3	viability	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-0.5224301495203121	[396,315]	[152,244]	-5	hSpCas9	negative selection	4441583
33062044	33062066	9	-	27760321	OCIAML3	viability	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-2.706516429038053	[192,151]	[0,45]	-9	hSpCas9	negative selection	4441584
33062123	33062145	9	+	27760321	OCIAML3	viability	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-1.210554638445278	[246,200]	[50,106]	-8	hSpCas9	negative selection	4441585
33068859	33068881	9	-	27760321	OCIAML3	viability	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.1172874803352397	[412,310]	[19,122]	-9	hSpCas9	negative selection	4441586
33071727	33071749	9	+	27760321	OCIAML3	viability	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-1.8494658492529958	[773,632]	[157,143]	-9	hSpCas9	negative selection	4441587
33060538	33060560	9	-	27760321	OCIAML2	viability	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-0.24059228309314118	[396,315]	[255,224]	-3	hSpCas9	negative selection	4525046
33062044	33062066	9	-	27760321	OCIAML2	viability	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-2.161614679302641	[192,151]	[11,55]	-9	hSpCas9	negative selection	4525047
33062123	33062145	9	+	27760321	OCIAML2	viability	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-2.3635793367978852	[246,200]	[9,67]	-9	hSpCas9	negative selection	4525048
33068859	33068881	9	-	27760321	OCIAML2	viability	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.5251473485934484	[412,310]	[46,54]	-9	hSpCas9	negative selection	4525049
33071727	33071749	9	+	27760321	OCIAML2	viability	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-2.4960511602083777	[773,632]	[127,63]	-9	hSpCas9	negative selection	4525050
33060538	33060560	9	-	27760321	MV411	viability	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-1.1442636328227955	[396,315]	[94,121]	-6	hSpCas9	negative selection	4608509
33062044	33062066	9	-	27760321	MV411	viability	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-2.954625916315413	[192,151]	[0,34]	-9	hSpCas9	negative selection	4608510
33062123	33062145	9	+	27760321	MV411	viability	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-0.8473883667512462	[246,200]	[0,202]	-5	hSpCas9	negative selection	4608511
33068859	33068881	9	-	27760321	MV411	viability	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-5.001680746537933	[412,310]	[0,16]	-9	hSpCas9	negative selection	4608512
33071727	33071749	9	+	27760321	MV411	viability	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-2.1165449871657347	[773,632]	[14,243]	-8	hSpCas9	negative selection	4608513
33060538	33060560	9	-	27760321	HL60	viability	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	0.300254427261126	[396,315]	[353,358]	4	hSpCas9	negative selection	4691972
33062044	33062066	9	-	27760321	HL60	viability	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-1.729363061325066	[192,151]	[32,51]	-9	hSpCas9	negative selection	4691973
33062123	33062145	9	+	27760321	HL60	viability	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-3.0371955057828437	[246,200]	[27,15]	-9	hSpCas9	negative selection	4691974
33068859	33068881	9	-	27760321	HL60	viability	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.663192178038264	[412,310]	[22,70]	-9	hSpCas9	negative selection	4691975
33071727	33071749	9	+	27760321	HL60	viability	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-1.4805004973844336	[773,632]	[218,189]	-8	hSpCas9	negative selection	4691976
33060538	33060560	9	-	27760321	HT1080	viability	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-6.809309202728067	[315,246]	[0,0]	-9	hSpCas9	negative selection	4775435
33062044	33062066	9	-	27760321	HT1080	viability	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-5.754609744218425	[151,118]	[0,0]	-8	hSpCas9	negative selection	4775436
33062123	33062145	9	+	27760321	HT1080	viability	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-6.1560708896411125	[200,156]	[0,0]	-9	hSpCas9	negative selection	4775437
33068859	33068881	9	-	27760321	HT1080	viability	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-6.786026536543369	[310,242]	[0,0]	-9	hSpCas9	negative selection	4775438
33071727	33071749	9	+	27760321	HT1080	viability	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-7.810448705180982	[632,493]	[0,0]	-9	hSpCas9	negative selection	4775439
33060538	33060560	9	-	27760321	HT29	viability after 7 days	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-1.2414725970825786	[315,246]	[277,113,86]	-9	hSpCas9	negative selection	4858898
33062044	33062066	9	-	27760321	HT29	viability after 7 days	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-5.983452312262598	[151,118]	[0,3,2]	-9	hSpCas9	negative selection	4858899
33062123	33062145	9	+	27760321	HT29	viability after 7 days	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-5.222975517574766	[200,156]	[2,7,6]	-9	hSpCas9	negative selection	4858900
33068859	33068881	9	-	27760321	HT29	viability after 7 days	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-3.908227988289318	[310,242]	[2,3,59]	-9	hSpCas9	negative selection	4858901
33071727	33071749	9	+	27760321	HT29	viability after 7 days	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-3.6784620692295023	[632,493]	[32,34,96]	-9	hSpCas9	negative selection	4858902
33060538	33060560	9	-	27760321	HT29	viability after 25 days	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-4.970990206787127	[315,246]	[4,7,18]	-9	hSpCas9	negative selection	4942361
33062044	33062066	9	-	27760321	HT29	viability after 25 days	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-7.274292009064949	[151,118]	[0,0,0]	-9	hSpCas9	negative selection	4942362
33062123	33062145	9	+	27760321	HT29	viability after 25 days	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-7.675753154487636	[200,156]	[0,0,0]	-9	hSpCas9	negative selection	4942363
33068859	33068881	9	-	27760321	HT29	viability after 25 days	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-3.0879997894115347	[310,242]	[0,74,37]	-8	hSpCas9	negative selection	4942364
33071727	33071749	9	+	27760321	HT29	viability after 25 days	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-9.330130970027506	[632,493]	[0,0,0]	-9	hSpCas9	negative selection	4942365
33060538	33060560	9	-	27760321	HT29	viability after 22 days	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-4.709107660101214	[315,246]	[22,5,7]	-9	hSpCas9	negative selection	5025824
33062044	33062066	9	-	27760321	HT29	viability after 22 days	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-7.291610640924208	[151,118]	[0,0,0]	-9	hSpCas9	negative selection	5025825
33062123	33062145	9	+	27760321	HT29	viability after 22 days	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-7.693071786346896	[200,156]	[0,0,0]	-9	hSpCas9	negative selection	5025826
33068859	33068881	9	-	27760321	HT29	viability after 22 days	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-6.601534155718257	[310,242]	[0,0,7]	-9	hSpCas9	negative selection	5025827
33071727	33071749	9	+	27760321	HT29	viability after 22 days	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-8.937918900922847	[632,493]	[0,0,1]	-9	hSpCas9	negative selection	5025828
33060538	33060560	9	-	27760321	HT29	viability after 19 days	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-3.1869608817881785	[315,246]	[101,1,9]	-8	hSpCas9	negative selection	5109287
33062044	33062066	9	-	27760321	HT29	viability after 19 days	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-7.275770588500995	[151,118]	[0,0,0]	-9	hSpCas9	negative selection	5109288
33062123	33062145	9	+	27760321	HT29	viability after 19 days	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-5.537035407643141	[200,156]	[0,10,0]	-9	hSpCas9	negative selection	5109289
33068859	33068881	9	-	27760321	HT29	viability after 19 days	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-4.852603506628243	[310,242]	[0,23,6]	-9	hSpCas9	negative selection	5109290
33071727	33071749	9	+	27760321	HT29	viability after 19 days	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-6.85207197296798	[632,493]	[15,0,0]	-9	hSpCas9	negative selection	5109291
33060538	33060560	9	-	27760321	HT29	viability after 16 days	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-3.3404750315395635	[315,246]	[26,26,38]	-9	hSpCas9	negative selection	5192750
33062044	33062066	9	-	27760321	HT29	viability after 16 days	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-7.244306136080073	[151,118]	[0,0,0]	-9	hSpCas9	negative selection	5192751
33062123	33062145	9	+	27760321	HT29	viability after 16 days	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-7.645767281502761	[200,156]	[0,0,0]	-9	hSpCas9	negative selection	5192752
33068859	33068881	9	-	27760321	HT29	viability after 16 days	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-6.8570979806099155	[310,242]	[1,0,4]	-9	hSpCas9	negative selection	5192753
33071727	33071749	9	+	27760321	HT29	viability after 16 days	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-4.856832665964614	[632,493]	[40,24,0]	-9	hSpCas9	negative selection	5192754
33060538	33060560	9	-	27760321	HT29	viability after 13 days	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-1.9243515970392917	[315,246]	[57,127,72]	-8	hSpCas9	negative selection	5276213
33062044	33062066	9	-	27760321	HT29	viability after 13 days	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-7.296593535524211	[151,118]	[0,0,0]	-9	hSpCas9	negative selection	5276214
33062123	33062145	9	+	27760321	HT29	viability after 13 days	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-7.698054680946899	[200,156]	[0,0,0]	-9	hSpCas9	negative selection	5276215
33068859	33068881	9	-	27760321	HT29	viability after 13 days	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-5.2940046217363115	[310,242]	[16,6,0]	-9	hSpCas9	negative selection	5276216
33071727	33071749	9	+	27760321	HT29	viability after 13 days	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-5.019255429952342	[632,493]	[12,1,43]	-9	hSpCas9	negative selection	5276217
33060538	33060560	9	-	27760321	HT29	viability after 10 days	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-1.2482398931671363	[315,246]	[81,239,124]	-8	hSpCas9	negative selection	5359676
33062044	33062066	9	-	27760321	HT29	viability after 10 days	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-5.648211752778327	[151,118]	[0,1,6]	-9	hSpCas9	negative selection	5359677
33062123	33062145	9	+	27760321	HT29	viability after 10 days	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-5.927717121721962	[200,156]	[8,0,0]	-9	hSpCas9	negative selection	5359678
33068859	33068881	9	-	27760321	HT29	viability after 10 days	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-5.013556990932573	[310,242]	[26,0,3]	-9	hSpCas9	negative selection	5359679
33071727	33071749	9	+	27760321	HT29	viability after 10 days	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-5.486932588322963	[632,493]	[9,16,19]	-9	hSpCas9	negative selection	5359680
33060538	33060560	9	-	27760321	MOLM13	viability	GTGCTCGATTTTCTCCAGATGG	SMU1	ENSG00000122692	-2.184573325802728	[396,315]	[50,37]	-8	hSpCas9	negative selection	5443139
33062044	33062066	9	-	27760321	MOLM13	viability	TGAGCAGGCATATTAAGGTAGG	SMU1	ENSG00000122692	-1.0601222838276414	[192,151]	[0,84]	-6	hSpCas9	negative selection	5443140
33062123	33062145	9	+	27760321	MOLM13	viability	AATCTATGGTCATACCAGGAGG	SMU1	ENSG00000122692	-3.9702005117710275	[246,200]	[0,13]	-9	hSpCas9	negative selection	5443141
33068859	33068881	9	-	27760321	MOLM13	viability	TTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-3.5199764047815405	[412,310]	[28,7]	-9	hSpCas9	negative selection	5443142
33071727	33071749	9	+	27760321	MOLM13	viability	ACCACAGTCATACCTCACGAGG	SMU1	ENSG00000122692	-0.6200793198793597	[773,632]	[95,393]	-4	hSpCas9	negative selection	5443143
33076423	33076446	9	-	27661255	K562	viability	GGATCTCGCTACCTCGGAGGTGG	SMU1	ENSG00000122692	-1.5926191639812004	[698,587]	[211,135]	-9	dCas9-KRAB	negative selection	5513091
33076611	33076634	9	-	27661255	K562	viability	GGCCTGCTCCCGGAGAGATACGG	SMU1	ENSG00000122692	-6.411950768818426	[145,165]	[1,0]	-9	dCas9-KRAB	negative selection	5513092
33073595	33073618	9	-	27260156	BXPC3	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.4399233035147931	[607]	[175,281,183,304]	-9	hSpCas9	negative selection	5571928
33068860	33068883	9	+	27260156	BXPC3	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.7230541697743323	[626]	[392,371,353,477]	-8	hSpCas9	negative selection	5571929
33073586	33073609	9	+	27260156	BXPC3	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.3241187645887322	[926]	[358,401,342,450]	-9	hSpCas9	negative selection	5571930
33062109	33062132	9	+	27260156	BXPC3	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.2287616494576714	[261]	[89,79,145,161]	-9	hSpCas9	negative selection	5636181
33068859	33068882	9	-	27260156	BXPC3	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.757433797687308	[422]	[142,71,91,228]	-9	hSpCas9	negative selection	5636182
33062113	33062136	9	-	27260156	BXPC3	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.10913608624066096	[128]	[39,139,147,187]	-3	hSpCas9	negative selection	5636183
33073595	33073618	9	-	27260156	A673	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.7157958834306539	[607]	[502,414,346,524]	-9	hSpCas9	negative selection	5693179
33068860	33068883	9	+	27260156	A673	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.2678126375903364	[626]	[700,615,544,648]	-6	hSpCas9	negative selection	5693180
33073586	33073609	9	+	27260156	A673	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.6664352653520706	[926]	[799,578,665,777]	-9	hSpCas9	negative selection	5693181
33062109	33062132	9	+	27260156	A673	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.0719677131574703	[261]	[146,164,145,138]	-9	hSpCas9	negative selection	5757432
33068859	33068882	9	-	27260156	A673	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.1397051843367592	[422]	[190,232,242,250]	-9	hSpCas9	negative selection	5757433
33062113	33062136	9	-	27260156	A673	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.4115157171298438	[128]	[104,121,77,161]	-7	hSpCas9	negative selection	5757434
33073595	33073618	9	-	27260156	A375	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.957557004257868	[607]	[233,157,276,71]	-9	hSpCas9	negative selection	5814430
33068860	33068883	9	+	27260156	A375	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.430643133700817	[626]	[222,334,309,230]	-9	hSpCas9	negative selection	5814431
33073586	33073609	9	+	27260156	A375	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-2.1400917909244552	[926]	[290,260,222,212]	-9	hSpCas9	negative selection	5814432
33062109	33062132	9	+	27260156	A375	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.4605528510279766	[261]	[73,43,124,182]	-9	hSpCas9	negative selection	5878683
33068859	33068882	9	-	27260156	A375	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.2253468863090036	[422]	[210,94,69,51]	-9	hSpCas9	negative selection	5878684
33062113	33062136	9	-	27260156	A375	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.5234741884749037	[128]	[50,132,55,173]	-6	hSpCas9	negative selection	5878685
33073595	33073618	9	-	27260156	COLO741	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.47481936356707233	[607]	[655,597,438]	-7	hSpCas9	negative selection	5935681
33068860	33068883	9	+	27260156	COLO741	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.4026661282522279	[626]	[727,676,434]	-7	hSpCas9	negative selection	5935682
33073586	33073609	9	+	27260156	COLO741	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.782122660773044	[926]	[665,737,660]	-9	hSpCas9	negative selection	5935683
33062109	33062132	9	+	27260156	COLO741	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.88249518064431	[261]	[152,56,68]	-9	hSpCas9	negative selection	5999934
33068859	33068882	9	-	27260156	COLO741	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.8291987281888165	[422]	[183,155,120]	-9	hSpCas9	negative selection	5999935
33062113	33062136	9	-	27260156	COLO741	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.3423071875892234	[128]	[172,127,94]	-6	hSpCas9	negative selection	5999936
33073595	33073618	9	-	27260156	CAL120	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.5136566601634664	[607]	[355,270,182]	-9	hSpCas9	negative selection	6056932
33068860	33068883	9	+	27260156	CAL120	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.3546632932642984	[626]	[484,251,206]	-9	hSpCas9	negative selection	6056933
33073586	33073609	9	+	27260156	CAL120	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-2.25770666125156	[926]	[342,218,177]	-9	hSpCas9	negative selection	6056934
33062109	33062132	9	+	27260156	CAL120	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.5020920791846215	[261]	[214,69,75]	-9	hSpCas9	negative selection	6121185
33068859	33068882	9	-	27260156	CAL120	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.723111349079511	[422]	[175,215,89]	-9	hSpCas9	negative selection	6121186
33062113	33062136	9	-	27260156	CAL120	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.4659248758861854	[128]	[78,70,27]	-9	hSpCas9	negative selection	6121187
33073595	33073618	9	-	27260156	CADOES1	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.7818815923092706	[607]	[364,217,331,402]	-8	hSpCas9	negative selection	6178183
33068860	33068883	9	+	27260156	CADOES1	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.8346051251930967	[626]	[331,257,461,252]	-9	hSpCas9	negative selection	6178184
33073586	33073609	9	+	27260156	CADOES1	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.1104773863685604	[926]	[391,402,408,392]	-9	hSpCas9	negative selection	6178185
33062109	33062132	9	+	27260156	CADOES1	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-0.17260732182965755	[261]	[235,109,365,149]	-3	hSpCas9	negative selection	6242436
33068859	33068882	9	-	27260156	CADOES1	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.3933679792075453	[422]	[108,113,176,200]	-9	hSpCas9	negative selection	6242437
33062113	33062136	9	-	27260156	CADOES1	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.07230268045946708	[128]	[143,88,91,131]	-1	hSpCas9	negative selection	6242438
33073595	33073618	9	-	27260156	EWS502	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.1781452020338854	[607]	[133,324,325,375]	-9	hSpCas9	negative selection	6299434
33068860	33068883	9	+	27260156	EWS502	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.4994815911986987	[626]	[189,277,164,313]	-9	hSpCas9	negative selection	6299435
33073586	33073609	9	+	27260156	EWS502	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.9450967745852479	[926]	[169,355,259,237]	-9	hSpCas9	negative selection	6299436
33062109	33062132	9	+	27260156	EWS502	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-2.228876633523389	[261]	[41,14,98,86]	-9	hSpCas9	negative selection	6363687
33068859	33068882	9	-	27260156	EWS502	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.275540145999939	[422]	[17,59,191,112]	-9	hSpCas9	negative selection	6363688
33062113	33062136	9	-	27260156	EWS502	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.800251270264648	[128]	[27,64,136,91]	-8	hSpCas9	negative selection	6363689
33073595	33073618	9	-	27260156	EW8	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.0607497332314435	[607]	[201,238,219,281]	-9	hSpCas9	negative selection	6420685
33068860	33068883	9	+	27260156	EW8	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.40007602699250194	[626]	[376,394,368,399]	-6	hSpCas9	negative selection	6420686
33073586	33073609	9	+	27260156	EW8	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.9670928275295769	[926]	[732,344,252,265]	-9	hSpCas9	negative selection	6420687
33062109	33062132	9	+	27260156	EW8	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.7605737147059635	[261]	[79,56,64,49]	-9	hSpCas9	negative selection	6484938
33068859	33068882	9	-	27260156	EW8	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.3611628063829784	[422]	[139,150,74,177]	-9	hSpCas9	negative selection	6484939
33062113	33062136	9	-	27260156	EW8	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.6139392222016793	[128]	[75,51,72,71]	-8	hSpCas9	negative selection	6484940
33073595	33073618	9	-	27260156	CORL105	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.8380072482141974	[607]	[463,226,355,543]	-9	hSpCas9	negative selection	6541936
33068860	33068883	9	+	27260156	CORL105	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.8184128489337124	[626]	[411,345,667,279]	-8	hSpCas9	negative selection	6541937
33073586	33073609	9	+	27260156	CORL105	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.0783648931685739	[926]	[509,542,426,560]	-9	hSpCas9	negative selection	6541938
33062109	33062132	9	+	27260156	CORL105	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.0863540502902573	[261]	[123,118,135,196]	-9	hSpCas9	negative selection	6606189
33068859	33068882	9	-	27260156	CORL105	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.270472738581298	[422]	[164,234,298,134]	-9	hSpCas9	negative selection	6606190
33062113	33062136	9	-	27260156	CORL105	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.229434628015724	[128]	[64,119,216,124]	-4	hSpCas9	negative selection	6606191
33073595	33073618	9	-	27260156	HS294T	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.2101368545159032	[607]	[53,66,148,149]	-9	hSpCas9	negative selection	6663187
33068860	33068883	9	+	27260156	HS294T	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.0157612617845648	[626]	[62,49,164,226]	-9	hSpCas9	negative selection	6663188
33073586	33073609	9	+	27260156	HS294T	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.4882829977630416	[926]	[97,65,151,213]	-9	hSpCas9	negative selection	6663189
33062109	33062132	9	+	27260156	HS294T	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.9194714436412126	[261]	[20,15,28,44]	-9	hSpCas9	negative selection	6727440
33068859	33068882	9	-	27260156	HS294T	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.2590164166270816	[422]	[19,21,43,55]	-9	hSpCas9	negative selection	6727441
33062113	33062136	9	-	27260156	HS294T	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	0.6081160679041517	[128]	[102,33,102,59]	7	hSpCas9	negative selection	6727442
33073595	33073618	9	-	27260156	HCC44	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-2.303919102275387	[607]	[76,173,235,76]	-9	hSpCas9	negative selection	6784438
33068860	33068883	9	+	27260156	HCC44	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-2.553651199274293	[626]	[145,164,82,78]	-9	hSpCas9	negative selection	6784439
33073586	33073609	9	+	27260156	HCC44	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-2.393810579188819	[926]	[273,126,118,276]	-9	hSpCas9	negative selection	6784440
33062109	33062132	9	+	27260156	HCC44	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-2.8459786815275647	[261]	[25,52,33,46]	-9	hSpCas9	negative selection	6848691
33068859	33068882	9	-	27260156	HCC44	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.6904873186473073	[422]	[42,30,115,114]	-9	hSpCas9	negative selection	6848692
33062113	33062136	9	-	27260156	HCC44	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.124124982728507	[128]	[47,67,92,60]	-8	hSpCas9	negative selection	6848693
33073595	33073618	9	-	27260156	G402	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.242470381363916	[607]	[283,332,300,330]	-8	hSpCas9	negative selection	6905689
33068860	33068883	9	+	27260156	G402	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.814931789792094	[626]	[438,589,336,383]	-7	hSpCas9	negative selection	6905690
33073586	33073609	9	+	27260156	G402	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.3471644560635843	[926]	[838,402,160,428]	-9	hSpCas9	negative selection	6905691
33062109	33062132	9	+	27260156	G402	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.2049712574157934	[261]	[209,162,77,115]	-8	hSpCas9	negative selection	6969942
33068859	33068882	9	-	27260156	G402	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.5546777727052292	[422]	[105,521,31,57]	-9	hSpCas9	negative selection	6969943
33062113	33062136	9	-	27260156	G402	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.33156872101092927	[128]	[72,116,221,81]	-4	hSpCas9	negative selection	6969944
33073595	33073618	9	-	27260156	L33	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.06607997784521352	[607]	[524,222,358,682]	-1	hSpCas9	negative selection	7026940
33068860	33068883	9	+	27260156	L33	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	0.35946224930587395	[626]	[666,334,514,915]	7	hSpCas9	negative selection	7026941
33073586	33073609	9	+	27260156	L33	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.26041243944152614	[926]	[803,306,512,725]	-6	hSpCas9	negative selection	7026942
33062109	33062132	9	+	27260156	L33	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-0.9037776919676854	[261]	[144,69,65,138]	-9	hSpCas9	negative selection	7091193
33068859	33068882	9	-	27260156	L33	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-0.939137436825331	[422]	[207,81,133,260]	-9	hSpCas9	negative selection	7091194
33062113	33062136	9	-	27260156	L33	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	0.31755125047011457	[128]	[114,57,97,230]	6	hSpCas9	negative selection	7091195
33073595	33073618	9	-	27260156	K562	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.591175518978388	[607]	[246,212,131,135]	-9	hSpCas9	negative selection	7148191
33068860	33068883	9	+	27260156	K562	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.3273728845260921	[626]	[271,105,387,128]	-8	hSpCas9	negative selection	7148192
33073586	33073609	9	+	27260156	K562	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-3.8601251389960662	[926]	[70,67,68,23]	-9	hSpCas9	negative selection	7148193
33062109	33062132	9	+	27260156	K562	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-2.705952513328244	[261]	[76,16,35,16]	-9	hSpCas9	negative selection	7212444
33068859	33068882	9	-	27260156	K562	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.4974203116219362	[422]	[142,22,87,20]	-9	hSpCas9	negative selection	7212445
33062113	33062136	9	-	27260156	K562	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.9067706596348375	[128]	[47,62,117,18]	-8	hSpCas9	negative selection	7212446
33073595	33073618	9	-	27260156	HT29	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-2.0673326070781606	[607]	[193,191,217,110]	-9	hSpCas9	negative selection	7269442
33068860	33068883	9	+	27260156	HT29	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.4538727509417613	[626]	[325,257,314,220]	-9	hSpCas9	negative selection	7269443
33073586	33073609	9	+	27260156	HT29	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-2.3582748490355274	[926]	[378,151,187,170]	-9	hSpCas9	negative selection	7269444
33062109	33062132	9	+	27260156	HT29	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.7143198636381427	[261]	[96,84,120,84]	-9	hSpCas9	negative selection	7333695
33068859	33068882	9	-	27260156	HT29	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.865379497755449	[422]	[52,118,81,34]	-9	hSpCas9	negative selection	7333696
33062113	33062136	9	-	27260156	HT29	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.7664688362174374	[128]	[181,71,24,93]	-8	hSpCas9	negative selection	7333697
33073595	33073618	9	-	27260156	MHHES1	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.9797287944136578	[607]	[661,212,246,294]	-9	hSpCas9	negative selection	7390693
33068860	33068883	9	+	27260156	MHHES1	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.673412936948849	[626]	[586,526,408,297]	-8	hSpCas9	negative selection	7390694
33073586	33073609	9	+	27260156	MHHES1	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.5348304404147274	[926]	[876,674,650,684]	-7	hSpCas9	negative selection	7390695
33062109	33062132	9	+	27260156	MHHES1	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.0879791221973545	[261]	[185,68,137,153]	-9	hSpCas9	negative selection	7454946
33068859	33068882	9	-	27260156	MHHES1	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.514300825852025	[422]	[151,274,73,169]	-9	hSpCas9	negative selection	7454947
33062113	33062136	9	-	27260156	MHHES1	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.21252850065469864	[128]	[239,142,22,110]	-4	hSpCas9	negative selection	7454948
33073595	33073618	9	-	27260156	MEWO	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.456256897497487	[607]	[412,495,333]	-7	hSpCas9	negative selection	7511944
33068860	33068883	9	+	27260156	MEWO	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.19409423035298076	[626]	[504,441,589]	-4	hSpCas9	negative selection	7511945
33073586	33073609	9	+	27260156	MEWO	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.4837751982943235	[926]	[557,490,799]	-8	hSpCas9	negative selection	7511946
33062109	33062132	9	+	27260156	MEWO	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.5923666747674303	[261]	[101,51,93]	-9	hSpCas9	negative selection	7576197
33068859	33068882	9	-	27260156	MEWO	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.6664849099881243	[422]	[185,94,104]	-9	hSpCas9	negative selection	7576198
33062113	33062136	9	-	27260156	MEWO	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.2219080227858796	[128]	[55,58,40]	-9	hSpCas9	negative selection	7576199
33073595	33073618	9	-	27260156	LNCAPCLONEFGC	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.1783766340833166	[607]	[280,229,206,249]	-9	hSpCas9	negative selection	7633195
33068860	33068883	9	+	27260156	LNCAPCLONEFGC	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.8870722903531731	[626]	[300,217,318,397]	-8	hSpCas9	negative selection	7633196
33073586	33073609	9	+	27260156	LNCAPCLONEFGC	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.129625912361498	[926]	[333,401,365,429]	-9	hSpCas9	negative selection	7633197
33062109	33062132	9	+	27260156	LNCAPCLONEFGC	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.5410877830383127	[261]	[117,56,107,47]	-9	hSpCas9	negative selection	7697448
33068859	33068882	9	-	27260156	LNCAPCLONEFGC	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.9536241491597854	[422]	[89,94,111,100]	-9	hSpCas9	negative selection	7697449
33062113	33062136	9	-	27260156	LNCAPCLONEFGC	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.7501175978261203	[128]	[47,80,65,81]	-8	hSpCas9	negative selection	7697450
33073595	33073618	9	-	27260156	PANC0327	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.8404758253606686	[607]	[218,88,252,55]	-9	hSpCas9	negative selection	7754446
33068860	33068883	9	+	27260156	PANC0327	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.8382667952937137	[626]	[215,203,353,477]	-8	hSpCas9	negative selection	7754447
33073586	33073609	9	+	27260156	PANC0327	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.538258304407733	[926]	[220,234,261,416]	-9	hSpCas9	negative selection	7754448
33062109	33062132	9	+	27260156	PANC0327	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.5680873629936454	[261]	[107,95,21,87]	-9	hSpCas9	negative selection	7818699
33068859	33068882	9	-	27260156	PANC0327	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.139828491581576	[422]	[69,121,66,75]	-9	hSpCas9	negative selection	7818700
33062113	33062136	9	-	27260156	PANC0327	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.2585487853306756	[128]	[76,23,31,63]	-9	hSpCas9	negative selection	7818701
33073595	33073618	9	-	27260156	NCIH2009	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-2.102215136749816	[607]	[191,309,87]	-9	hSpCas9	negative selection	7875697
33068860	33068883	9	+	27260156	NCIH2009	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-2.4002350667310046	[626]	[284,170,64]	-9	hSpCas9	negative selection	7875698
33073586	33073609	9	+	27260156	NCIH2009	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-3.0944037751338542	[926]	[253,145,74]	-9	hSpCas9	negative selection	7875699
33062109	33062132	9	+	27260156	NCIH2009	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-2.6740290777713316	[261]	[40,42,84]	-9	hSpCas9	negative selection	7939950
33068859	33068882	9	-	27260156	NCIH2009	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.9476484367737963	[422]	[96,115,19]	-9	hSpCas9	negative selection	7939951
33062113	33062136	9	-	27260156	NCIH2009	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.9172218834426331	[128]	[70,29,46]	-9	hSpCas9	negative selection	7939952
33073595	33073618	9	-	27260156	NCIH1373	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.9930955610666098	[607]	[916,226,109,55]	-7	hSpCas9	negative selection	7996948
33068860	33068883	9	+	27260156	NCIH1373	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.8497496712048094	[626]	[252,157,165,56]	-9	hSpCas9	negative selection	7996949
33073586	33073609	9	+	27260156	NCIH1373	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.334744957958356	[926]	[535,429,256,116]	-8	hSpCas9	negative selection	7996950
33062109	33062132	9	+	27260156	NCIH1373	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-0.6203757149646814	[261]	[235,336,106,17]	-6	hSpCas9	negative selection	8061201
33068859	33068882	9	-	27260156	NCIH1373	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-3.9948283549138686	[422]	[14,27,28,11]	-9	hSpCas9	negative selection	8061202
33062113	33062136	9	-	27260156	NCIH1373	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.20371235222761652	[128]	[78,123,87,54]	-2	hSpCas9	negative selection	8061203
33073595	33073618	9	-	27260156	PATU8902	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-2.1973379135571016	[607]	[132,415,12,225]	-9	hSpCas9	negative selection	8118199
33068860	33068883	9	+	27260156	PATU8902	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-2.4217476031541443	[626]	[267,25,189,156]	-9	hSpCas9	negative selection	8118200
33073586	33073609	9	+	27260156	PATU8902	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-2.6029684469659298	[926]	[95,326,266,136]	-9	hSpCas9	negative selection	8118201
33062109	33062132	9	+	27260156	PATU8902	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.049767769517354	[261]	[135,144,77,396]	-7	hSpCas9	negative selection	8182452
33068859	33068882	9	-	27260156	PATU8902	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.7365737743396397	[422]	[331,64,252,13]	-8	hSpCas9	negative selection	8182453
33062113	33062136	9	-	27260156	PATU8902	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.6541216600631163	[128]	[42,169,12,7]	-8	hSpCas9	negative selection	8182454
33073595	33073618	9	-	27260156	PANC1	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.9744131847165158	[607]	[147,245,94,72]	-9	hSpCas9	negative selection	8239450
33068860	33068883	9	+	27260156	PANC1	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-2.4578555352466274	[626]	[154,100,125,20]	-9	hSpCas9	negative selection	8239451
33073586	33073609	9	+	27260156	PANC1	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-2.631148749974257	[926]	[103,131,139,135]	-9	hSpCas9	negative selection	8239452
33062109	33062132	9	+	27260156	PANC1	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.6042353919914347	[261]	[39,79,115,62]	-9	hSpCas9	negative selection	8303703
33068859	33068882	9	-	27260156	PANC1	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.4405697988702757	[422]	[87,114,8,63]	-9	hSpCas9	negative selection	8303704
33062113	33062136	9	-	27260156	PANC1	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.410467172265746	[128]	[81,114,48,90]	-6	hSpCas9	negative selection	8303705
33073595	33073618	9	-	27260156	PANC0813	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.2731469135813493	[607]	[315,176,361,326]	-9	hSpCas9	negative selection	8360701
33068860	33068883	9	+	27260156	PANC0813	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.5339359223297315	[626]	[211,226,313,259]	-9	hSpCas9	negative selection	8360702
33073586	33073609	9	+	27260156	PANC0813	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.7973742439577698	[926]	[329,320,306,296]	-9	hSpCas9	negative selection	8360703
33062109	33062132	9	+	27260156	PANC0813	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.2837614903569448	[261]	[113,28,220,139]	-9	hSpCas9	negative selection	8424954
33068859	33068882	9	-	27260156	PANC0813	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-0.900052388406161	[422]	[280,95,134,537]	-8	hSpCas9	negative selection	8424955
33062113	33062136	9	-	27260156	PANC0813	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.6439863379180977	[128]	[80,107,95,100]	-7	hSpCas9	negative selection	8424956
33073595	33073618	9	-	27260156	RDES	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.1796531575252085	[607]	[323,296,259,343]	-9	hSpCas9	negative selection	8481952
33068860	33068883	9	+	27260156	RDES	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.0829985904364843	[626]	[395,263,360,320]	-9	hSpCas9	negative selection	8481953
33073586	33073609	9	+	27260156	RDES	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.3262381618271426	[926]	[423,319,391,583]	-9	hSpCas9	negative selection	8481954
33062109	33062132	9	+	27260156	RDES	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.0174526167909037	[261]	[134,68,176,234]	-9	hSpCas9	negative selection	8546205
33068859	33068882	9	-	27260156	RDES	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.7526685518966785	[422]	[142,103,197,131]	-9	hSpCas9	negative selection	8546206
33062113	33062136	9	-	27260156	RDES	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.43636217194406757	[128]	[126,120,61,118]	-6	hSpCas9	negative selection	8546207
33073595	33073618	9	-	27260156	PC3	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.41470901012534	[607]	[320,469,710,422]	-7	hSpCas9	negative selection	8603203
33068860	33068883	9	+	27260156	PC3	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.12995610528912394	[626]	[424,405,897,697]	-3	hSpCas9	negative selection	8603204
33073586	33073609	9	+	27260156	PC3	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.5972308386556798	[926]	[320,586,1262,603]	-8	hSpCas9	negative selection	8603205
33062109	33062132	9	+	27260156	PC3	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.552870974460591	[261]	[35,57,242,98]	-9	hSpCas9	negative selection	8667456
33068859	33068882	9	-	27260156	PC3	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.4051686640459784	[422]	[88,110,365,171]	-9	hSpCas9	negative selection	8667457
33062113	33062136	9	-	27260156	PC3	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.19636021438794216	[128]	[100,45,180,142]	-4	hSpCas9	negative selection	8667458
33073595	33073618	9	-	27260156	PATU8988T	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-1.2250660009870802	[607]	[205,410,187,212]	-9	hSpCas9	negative selection	8724454
33068860	33068883	9	+	27260156	PATU8988T	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-1.0503970386129162	[626]	[377,371,182,241]	-9	hSpCas9	negative selection	8724455
33073586	33073609	9	+	27260156	PATU8988T	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-2.154291690684871	[926]	[76,228,338,156]	-9	hSpCas9	negative selection	8724456
33062109	33062132	9	+	27260156	PATU8988T	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.9725315523276115	[261]	[64,58,43,91]	-9	hSpCas9	negative selection	8788707
33068859	33068882	9	-	27260156	PATU8988T	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.2937031950840825	[422]	[10,102,112,109]	-9	hSpCas9	negative selection	8788708
33062113	33062136	9	-	27260156	PATU8988T	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.26030634480983994	[128]	[184,56,79,88]	-4	hSpCas9	negative selection	8788709
33073595	33073618	9	-	27260156	T47D	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.8865754011885865	[607]	[391,338,332,475]	-9	hSpCas9	negative selection	8845705
33068860	33068883	9	+	27260156	T47D	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.8219076820557699	[626]	[361,407,408,475]	-9	hSpCas9	negative selection	8845706
33073586	33073609	9	+	27260156	T47D	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-1.2107448443797513	[926]	[424,453,484,503]	-9	hSpCas9	negative selection	8845707
33062109	33062132	9	+	27260156	T47D	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.4038749274497058	[261]	[111,134,115,95]	-9	hSpCas9	negative selection	8909958
33068859	33068882	9	-	27260156	T47D	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.0177307210069313	[422]	[105,86,150,145]	-9	hSpCas9	negative selection	8909959
33062113	33062136	9	-	27260156	T47D	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.07800109665255195	[128]	[194,78,136,164]	-2	hSpCas9	negative selection	8909960
33073595	33073618	9	-	27260156	SU8686	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-2.13184456458869	[607]	[114,66,168,224]	-9	hSpCas9	negative selection	8966956
33068860	33068883	9	+	27260156	SU8686	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-2.36928120105816	[626]	[75,117,173,118]	-9	hSpCas9	negative selection	8966957
33073586	33073609	9	+	27260156	SU8686	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-2.2999198617199763	[926]	[176,219,132,214]	-9	hSpCas9	negative selection	8966958
33062109	33062132	9	+	27260156	SU8686	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.416842074898329	[261]	[61,146,81,93]	-9	hSpCas9	negative selection	9031209
33068859	33068882	9	-	27260156	SU8686	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-2.713815197913427	[422]	[30,89,56,79]	-9	hSpCas9	negative selection	9031210
33062113	33062136	9	-	27260156	SU8686	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.6993351220048096	[128]	[23,51,25,57]	-9	hSpCas9	negative selection	9031211
33073595	33073618	9	-	27260156	SKES1	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.29721071599935894	[607]	[407,640,466,462]	-6	hSpCas9	negative selection	9088207
33068860	33068883	9	+	27260156	SKES1	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.1663611744177423	[626]	[627,686,511,436]	-4	hSpCas9	negative selection	9088208
33073586	33073609	9	+	27260156	SKES1	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.4892693175613838	[926]	[785,659,642,567]	-8	hSpCas9	negative selection	9088209
33062109	33062132	9	+	27260156	SKES1	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.533029589696495	[261]	[84,143,61,76]	-9	hSpCas9	negative selection	9152460
33068859	33068882	9	-	27260156	SKES1	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.2982767181994734	[422]	[264,187,120,130]	-9	hSpCas9	negative selection	9152461
33062113	33062136	9	-	27260156	SKES1	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	0.02808627126864316	[128]	[161,116,144,104]	0	hSpCas9	negative selection	9152462
33073595	33073618	9	-	27260156	TOV112D	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.4911414211969998	[607]	[358,508,492,384]	-7	hSpCas9	negative selection	9209458
33068860	33068883	9	+	27260156	TOV112D	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.7066233690676851	[626]	[293,483,417,359]	-8	hSpCas9	negative selection	9209459
33073586	33073609	9	+	27260156	TOV112D	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.23418731214192945	[926]	[711,1087,851,576]	-4	hSpCas9	negative selection	9209460
33062109	33062132	9	+	27260156	TOV112D	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-0.9390271675245374	[261]	[60,150,255,77]	-9	hSpCas9	negative selection	9273711
33068859	33068882	9	-	27260156	TOV112D	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.233585340250802	[422]	[152,134,312,107]	-9	hSpCas9	negative selection	9273712
33062113	33062136	9	-	27260156	TOV112D	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-1.5970170674643376	[128]	[27,28,60,47]	-9	hSpCas9	negative selection	9273713
33073595	33073618	9	-	27260156	TC71	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.5126783269630915	[607]	[424,665,340,395]	-8	hSpCas9	negative selection	9330709
33068860	33068883	9	+	27260156	TC71	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.034574159897575674	[626]	[615,676,734,590]	-1	hSpCas9	negative selection	9330710
33073586	33073609	9	+	27260156	TC71	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.19845421239211924	[926]	[767,881,801,1025]	-5	hSpCas9	negative selection	9330711
33062109	33062132	9	+	27260156	TC71	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-0.9596156987491669	[261]	[138,149,121,168]	-9	hSpCas9	negative selection	9394962
33068859	33068882	9	-	27260156	TC71	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-0.9952253723098449	[422]	[270,193,218,224]	-9	hSpCas9	negative selection	9394963
33062113	33062136	9	-	27260156	TC71	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.2340016535420648	[128]	[141,87,127,110]	-6	hSpCas9	negative selection	9394964
33073595	33073618	9	-	27260156	TC32	viability	CCTCATTGACCTCTATGAACAGG	SMU1	ENSG00000122692	-0.9470026242203661	[607]	[291,156,461,342]	-9	hSpCas9	negative selection	9451960
33068860	33068883	9	+	27260156	TC32	viability	CACACTGACTTCGCCAGCTAAGG	SMU1	ENSG00000122692	-0.21891587163453413	[626]	[455,456,581,537]	-4	hSpCas9	negative selection	9451961
33073586	33073609	9	+	27260156	TC32	viability	CCACTCTTACCTGTTCATAGAGG	SMU1	ENSG00000122692	-0.6251129131891724	[926]	[538,366,716,716]	-8	hSpCas9	negative selection	9451962
33062109	33062132	9	+	27260156	TC32	viability	CTTGCCTCGAAACAAATCTATGG	SMU1	ENSG00000122692	-1.0657852222820616	[261]	[134,80,170,95]	-9	hSpCas9	negative selection	9516213
33068859	33068882	9	-	27260156	TC32	viability	CTTAGCTGGCGAAGTCAGTGTGG	SMU1	ENSG00000122692	-1.0614830173445542	[422]	[118,239,173,203]	-9	hSpCas9	negative selection	9516214
33062113	33062136	9	-	27260156	TC32	viability	ATGACCATAGATTTGTTTCGAGG	SMU1	ENSG00000122692	-0.43776733419554037	[128]	[56,38,192,106]	-7	hSpCas9	negative selection	9516215
33047373	33047396	9	+	27869803	HPAFII	viability after 27 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	1.3092657129069003	[180]	[381,113,NaN]	9	hSpCas9	negative selection	9605756
33047373	33047396	9	+	27869803	HPAFII	viability after 15 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	1.439250600974721	[180]	[693,423,NaN]	9	hSpCas9	negative selection	9688205
33047373	33047396	9	+	27869803	ASPC1	viability after 36 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	0.5105815710506478	[660]	[421,330,257]	5	hSpCas9	negative selection	9770654
33047373	33047396	9	+	27869803	PATU8988S	viability after 35 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	0.4290554552846044	[556]	[314,288,NaN]	5	hSpCas9	negative selection	9853103
33047373	33047396	9	+	27869803	PATU8988S	viability after 31 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	0.26000701891666245	[556]	[272,256,NaN]	3	hSpCas9	negative selection	9935552
33047373	33047396	9	+	27869803	HPAFII	viability after 35 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	1.728894089068851	[180]	[354,245,NaN]	9	hSpCas9	negative selection	10018001
33047373	33047396	9	+	27869803	HPAFII	viability after 31 days	TCACATCCTTCTCGTGCACCTGG	SMU1	ENSG00000122692	1.6183659337073761	[180]	[364,253,NaN]	9	hSpCas9	negative selection	10100450
33053146	33053169	9	-	28162770	P31FUJ	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-7.0272180707644845	[110]	[0]	-9	hSpCas9	negative selection	10239534
33071830	33071853	9	+	28162770	P31FUJ	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-2.412508226649276	[443]	[97]	-8	hSpCas9	negative selection	10239535
33056945	33056968	9	-	28162770	P31FUJ	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-0.9725664319332581	[171]	[102]	-6	hSpCas9	negative selection	10239536
33053229	33053252	9	-	28162770	P31FUJ	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-5.46162089491026	[74]	[1]	-9	hSpCas9	negative selection	10239537
33060563	33060586	9	-	28162770	P31FUJ	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-1.5654998213367162	[873]	[346]	-7	hSpCas9	negative selection	10239538
33056110	33056133	9	+	28162770	P31FUJ	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-2.0603350084096133	[251]	[70]	-8	hSpCas9	negative selection	10239539
33053122	33053145	9	-	28162770	P31FUJ	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-0.9375592176702493	[250]	[153]	-6	hSpCas9	negative selection	10239540
33073709	33073732	9	-	28162770	P31FUJ	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-3.225570635183303	[198]	[24]	-9	hSpCas9	negative selection	10239541
33056195	33056218	9	-	28162770	P31FUJ	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-0.010409783077930612	[5]	[6]	0	hSpCas9	negative selection	10239542
33053213	33053236	9	+	28162770	P31FUJ	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-3.299780904143125	[1013]	[120]	-9	hSpCas9	negative selection	10239543
33053146	33053169	9	-	28162770	TF1	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10408900
33071830	33071853	9	+	28162770	TF1	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10408901
33056945	33056968	9	-	28162770	TF1	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10408902
33053229	33053252	9	-	28162770	TF1	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10408903
33060563	33060586	9	-	28162770	TF1	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	NaN	[NaN]	[125]	1	hSpCas9	negative selection	10408904
33056110	33056133	9	+	28162770	TF1	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	NaN	[NaN]	[104]	1	hSpCas9	negative selection	10408905
33053122	33053145	9	-	28162770	TF1	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10408906
33073709	33073732	9	-	28162770	TF1	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10408907
33056195	33056218	9	-	28162770	TF1	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10408908
33053213	33053236	9	+	28162770	TF1	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	NaN	[NaN]	[139]	1	hSpCas9	negative selection	10408909
33053146	33053169	9	-	28162770	SKM1	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-4.0950201924284215	[28]	[2]	-9	hSpCas9	negative selection	10578266
33071830	33071853	9	+	28162770	SKM1	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-2.6092723740362773	[106]	[30]	-9	hSpCas9	negative selection	10578267
33056945	33056968	9	-	28162770	SKM1	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-2.0443941193584534	[55]	[23]	-8	hSpCas9	negative selection	10578268
33053229	33053252	9	-	28162770	SKM1	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-2.406964198743162	[26]	[8]	-8	hSpCas9	negative selection	10578269
33060563	33060586	9	-	28162770	SKM1	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-2.1991593136297602	[212]	[81]	-8	hSpCas9	negative selection	10578270
33056110	33056133	9	+	28162770	SKM1	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-1.7051880330392555	[82]	[44]	-8	hSpCas9	negative selection	10578271
33053122	33053145	9	-	28162770	SKM1	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-1.6104975928282939	[56]	[32]	-8	hSpCas9	negative selection	10578272
33073709	33073732	9	-	28162770	SKM1	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-5.951284714966972	[34]	[0]	-9	hSpCas9	negative selection	10578273
33056195	33056218	9	-	28162770	SKM1	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10578274
33053213	33053236	9	+	28162770	SKM1	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-2.166960761564709	[220]	[86]	-8	hSpCas9	negative selection	10578275
33053146	33053169	9	-	28162770	SKM1	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-4.0950201924284215	[28]	[2]	-9	hSpCas9	negative selection	10747632
33071830	33071853	9	+	28162770	SKM1	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-2.6092723740362773	[106]	[30]	-9	hSpCas9	negative selection	10747633
33056945	33056968	9	-	28162770	SKM1	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-2.0443941193584534	[55]	[23]	-8	hSpCas9	negative selection	10747634
33053229	33053252	9	-	28162770	SKM1	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-2.406964198743162	[26]	[8]	-8	hSpCas9	negative selection	10747635
33060563	33060586	9	-	28162770	SKM1	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-2.1991593136297602	[212]	[81]	-8	hSpCas9	negative selection	10747636
33056110	33056133	9	+	28162770	SKM1	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-1.7051880330392555	[82]	[44]	-8	hSpCas9	negative selection	10747637
33053122	33053145	9	-	28162770	SKM1	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-1.6104975928282939	[56]	[32]	-8	hSpCas9	negative selection	10747638
33073709	33073732	9	-	28162770	SKM1	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-5.951284714966972	[34]	[0]	-9	hSpCas9	negative selection	10747639
33056195	33056218	9	-	28162770	SKM1	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10747640
33053213	33053236	9	+	28162770	SKM1	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-2.166960761564709	[220]	[86]	-8	hSpCas9	negative selection	10747641
33053146	33053169	9	-	28162770	PL21	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-3.0382651248357586	[150]	[7]	-9	hSpCas9	negative selection	10916998
33071830	33071853	9	+	28162770	PL21	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-1.544999911122586	[294]	[43]	-7	hSpCas9	negative selection	10916999
33056945	33056968	9	-	28162770	PL21	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-1.873570071693689	[260]	[30]	-8	hSpCas9	negative selection	10917000
33053229	33053252	9	-	28162770	PL21	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-1.937363909260615	[87]	[9]	-8	hSpCas9	negative selection	10917001
33060563	33060586	9	-	28162770	PL21	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-2.637963757824302	[900]	[62]	-9	hSpCas9	negative selection	10917002
33056110	33056133	9	+	28162770	PL21	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-2.2886075709725326	[347]	[30]	-8	hSpCas9	negative selection	10917003
33053122	33053145	9	-	28162770	PL21	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-2.0676327103511367	[182]	[18]	-8	hSpCas9	negative selection	10917004
33073709	33073732	9	-	28162770	PL21	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-1.713604652160261	[210]	[27]	-8	hSpCas9	negative selection	10917005
33056195	33056218	9	-	28162770	PL21	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-1.1217884803980427	[4]	[0]	-6	hSpCas9	negative selection	10917006
33053213	33053236	9	+	28162770	PL21	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-6.367182727096106	[568]	[2]	-9	hSpCas9	negative selection	10917007
33053146	33053169	9	-	28162770	P31FUJ	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-7.0272180707644845	[110]	[0]	-9	hSpCas9	negative selection	11086364
33071830	33071853	9	+	28162770	P31FUJ	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-2.412508226649276	[443]	[97]	-8	hSpCas9	negative selection	11086365
33056945	33056968	9	-	28162770	P31FUJ	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-0.9725664319332581	[171]	[102]	-6	hSpCas9	negative selection	11086366
33053229	33053252	9	-	28162770	P31FUJ	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-5.46162089491026	[74]	[1]	-9	hSpCas9	negative selection	11086367
33060563	33060586	9	-	28162770	P31FUJ	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-1.5654998213367162	[873]	[346]	-7	hSpCas9	negative selection	11086368
33056110	33056133	9	+	28162770	P31FUJ	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-2.0603350084096133	[251]	[70]	-8	hSpCas9	negative selection	11086369
33053122	33053145	9	-	28162770	P31FUJ	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-0.9375592176702493	[250]	[153]	-6	hSpCas9	negative selection	11086370
33073709	33073732	9	-	28162770	P31FUJ	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-3.225570635183303	[198]	[24]	-9	hSpCas9	negative selection	11086371
33056195	33056218	9	-	28162770	P31FUJ	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-0.010409783077930612	[5]	[6]	0	hSpCas9	negative selection	11086372
33053213	33053236	9	+	28162770	P31FUJ	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-3.299780904143125	[1013]	[120]	-9	hSpCas9	negative selection	11086373
33053146	33053169	9	-	28162770	OCIAML5	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-3.6386629327548032	[68]	[9]	-9	hSpCas9	negative selection	11255730
33071830	33071853	9	+	28162770	OCIAML5	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-4.2956732223396115	[271]	[24]	-9	hSpCas9	negative selection	11255731
33056945	33056968	9	-	28162770	OCIAML5	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-2.943989060305036	[161]	[37]	-8	hSpCas9	negative selection	11255732
33053229	33053252	9	-	28162770	OCIAML5	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-0.012531243057242847	[18]	[33]	0	hSpCas9	negative selection	11255733
33060563	33060586	9	-	28162770	OCIAML5	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-3.9489281101165856	[461]	[53]	-9	hSpCas9	negative selection	11255734
33056110	33056133	9	+	28162770	OCIAML5	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-2.254825740364404	[155]	[58]	-8	hSpCas9	negative selection	11255735
33053122	33053145	9	-	28162770	OCIAML5	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-0.8848565059816664	[88]	[86]	-5	hSpCas9	negative selection	11255736
33073709	33073732	9	-	28162770	OCIAML5	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-5.278331325566095	[85]	[3]	-9	hSpCas9	negative selection	11255737
33056195	33056218	9	-	28162770	OCIAML5	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-1.4370290715851537	[2]	[1]	-7	hSpCas9	negative selection	11255738
33053213	33053236	9	+	28162770	OCIAML5	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-2.6777610836245347	[474]	[133]	-8	hSpCas9	negative selection	11255739
33053146	33053169	9	-	28162770	EOL1	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-6.3515766337037025	[154]	[0]	-9	hSpCas9	negative selection	11425096
33071830	33071853	9	+	28162770	EOL1	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-2.0046119878790165	[456]	[59]	-8	hSpCas9	negative selection	11425097
33056945	33056968	9	-	28162770	EOL1	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-2.0754522284294654	[295]	[36]	-8	hSpCas9	negative selection	11425098
33053229	33053252	9	-	28162770	EOL1	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-6.08667948385272	[128]	[0]	-9	hSpCas9	negative selection	11425099
33060563	33060586	9	-	28162770	EOL1	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-0.4274110450849289	[1431]	[560]	-3	hSpCas9	negative selection	11425100
33056110	33056133	9	+	28162770	EOL1	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-0.9865709473432153	[597]	[158]	-6	hSpCas9	negative selection	11425101
33053122	33053145	9	-	28162770	EOL1	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	0.3395852708493785	[224]	[149]	3	hSpCas9	negative selection	11425102
33073709	33073732	9	-	28162770	EOL1	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-4.982342824037984	[179]	[2]	-9	hSpCas9	negative selection	11425103
33056195	33056218	9	-	28162770	EOL1	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-1.3973803233168276	[4]	[0]	-7	hSpCas9	negative selection	11425104
33053213	33053236	9	+	28162770	EOL1	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-1.5931673880711064	[984]	[171]	-7	hSpCas9	negative selection	11425105
33053146	33053169	9	-	28162770	MOLM13	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-1.1914553154991534	[198]	[62]	-6	hSpCas9	negative selection	11594462
33071830	33071853	9	+	28162770	MOLM13	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-4.832234343024435	[590]	[14]	-9	hSpCas9	negative selection	11594463
33056945	33056968	9	-	28162770	MOLM13	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-3.245547677125386	[222]	[16]	-8	hSpCas9	negative selection	11594464
33053229	33053252	9	-	28162770	MOLM13	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-3.5321106184554214	[79]	[4]	-8	hSpCas9	negative selection	11594465
33060563	33060586	9	-	28162770	MOLM13	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-3.577914308068546	[1023]	[61]	-8	hSpCas9	negative selection	11594466
33056110	33056133	9	+	28162770	MOLM13	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-0.8803300111617114	[442]	[173]	-5	hSpCas9	negative selection	11594467
33053122	33053145	9	-	28162770	MOLM13	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-5.359929643072741	[283]	[4]	-9	hSpCas9	negative selection	11594468
33073709	33073732	9	-	28162770	MOLM13	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-5.069051604313634	[324]	[6]	-9	hSpCas9	negative selection	11594469
33056195	33056218	9	-	28162770	MOLM13	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-1.854038713342784	[4]	[0]	-7	hSpCas9	negative selection	11594470
33053213	33053236	9	+	28162770	MOLM13	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-2.712124437521317	[860]	[94]	-8	hSpCas9	negative selection	11594471
33053146	33053169	9	-	28162770	HEL	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-6.872961006283686	[182]	[0]	-9	hSpCas9	negative selection	11763828
33071830	33071853	9	+	28162770	HEL	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-2.6282476972238302	[472]	[48]	-8	hSpCas9	negative selection	11763829
33056945	33056968	9	-	28162770	HEL	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-3.708936606281058	[244]	[11]	-9	hSpCas9	negative selection	11763830
33053229	33053252	9	-	28162770	HEL	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-1.8978295493623458	[63]	[10]	-7	hSpCas9	negative selection	11763831
33060563	33060586	9	-	28162770	HEL	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-3.6024248969947488	[1042]	[54]	-9	hSpCas9	negative selection	11763832
33056110	33056133	9	+	28162770	HEL	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-1.9251904715613573	[420]	[70]	-7	hSpCas9	negative selection	11763833
33053122	33053145	9	-	28162770	HEL	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-1.5575598184854742	[215]	[46]	-7	hSpCas9	negative selection	11763834
33073709	33073732	9	-	28162770	HEL	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-7.252078931307587	[237]	[0]	-9	hSpCas9	negative selection	11763835
33056195	33056218	9	-	28162770	HEL	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	0.22770133272151316	[7]	[5]	1	hSpCas9	negative selection	11763836
33053213	33053236	9	+	28162770	HEL	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-1.9329458551327885	[774]	[129]	-8	hSpCas9	negative selection	11763837
33053146	33053169	9	-	28162770	MV411	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-5.110114453835308	[163]	[3]	-9	hSpCas9	negative selection	11933194
33071830	33071853	9	+	28162770	MV411	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-1.4882038624360492	[362]	[108]	-7	hSpCas9	negative selection	11933195
33056945	33056968	9	-	28162770	MV411	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-2.5969115787570303	[157]	[21]	-9	hSpCas9	negative selection	11933196
33053229	33053252	9	-	28162770	MV411	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-4.00048996266081	[56]	[2]	-9	hSpCas9	negative selection	11933197
33060563	33060586	9	-	28162770	MV411	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-1.2815995353403886	[758]	[262]	-7	hSpCas9	negative selection	11933198
33056110	33056133	9	+	28162770	MV411	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-1.3334781168756789	[355]	[118]	-7	hSpCas9	negative selection	11933199
33053122	33053145	9	-	28162770	MV411	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-1.3066639862336205	[184]	[62]	-7	hSpCas9	negative selection	11933200
33073709	33073732	9	-	28162770	MV411	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-4.2010229500335186	[130]	[5]	-9	hSpCas9	negative selection	11933201
33056195	33056218	9	-	28162770	MV411	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-4.453002167358317	[25]	[0]	-9	hSpCas9	negative selection	11933202
33053213	33053236	9	+	28162770	MV411	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-2.502378961833271	[638]	[94]	-8	hSpCas9	negative selection	11933203
33053146	33053169	9	-	28162770	MONOMAC1	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-5.8552483298113485	[100]	[1]	-9	hSpCas9	negative selection	12102560
33071830	33071853	9	+	28162770	MONOMAC1	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-1.5392237809307159	[250]	[98]	-8	hSpCas9	negative selection	12102561
33056945	33056968	9	-	28162770	MONOMAC1	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-2.6418216897324496	[146]	[26]	-9	hSpCas9	negative selection	12102562
33053229	33053252	9	-	28162770	MONOMAC1	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	0.7556574381620897	[30]	[59]	7	hSpCas9	negative selection	12102563
33060563	33060586	9	-	28162770	MONOMAC1	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-2.047074340999809	[565]	[156]	-9	hSpCas9	negative selection	12102564
33056110	33056133	9	+	28162770	MONOMAC1	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-1.9389686941191093	[193]	[57]	-8	hSpCas9	negative selection	12102565
33053122	33053145	9	-	28162770	MONOMAC1	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-2.3562354419088076	[133]	[29]	-9	hSpCas9	negative selection	12102566
33073709	33073732	9	-	28162770	MONOMAC1	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-4.171041638526609	[109]	[6]	-9	hSpCas9	negative selection	12102567
33056195	33056218	9	-	28162770	MONOMAC1	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-1.1970368470595538	[1]	[0]	-7	hSpCas9	negative selection	12102568
33053213	33053236	9	+	28162770	MONOMAC1	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-2.1823900710951523	[391]	[98]	-9	hSpCas9	negative selection	12102569
33053146	33053169	9	-	28162770	OCIAML2	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-6.9941917812991745	[22]	[0]	-9	hSpCas9	negative selection	12271926
33071830	33071853	9	+	28162770	OCIAML2	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-2.006682725482371	[57]	[79]	-8	hSpCas9	negative selection	12271927
33056945	33056968	9	-	28162770	OCIAML2	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-0.5711567011961258	[25]	[96]	-4	hSpCas9	negative selection	12271928
33053229	33053252	9	-	28162770	OCIAML2	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-2.544630406685938	[19]	[18]	-8	hSpCas9	negative selection	12271929
33060563	33060586	9	-	28162770	OCIAML2	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-1.942892193213955	[119]	[172]	-8	hSpCas9	negative selection	12271930
33056110	33056133	9	+	28162770	OCIAML2	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-0.6310944974354071	[56]	[203]	-5	hSpCas9	negative selection	12271931
33053122	33053145	9	-	28162770	OCIAML2	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-1.7336642310759551	[29]	[49]	-8	hSpCas9	negative selection	12271932
33073709	33073732	9	-	28162770	OCIAML2	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-3.9300614438794588	[21]	[7]	-9	hSpCas9	negative selection	12271933
33056195	33056218	9	-	28162770	OCIAML2	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-1.4706298252421615	[0]	[1]	-7	hSpCas9	negative selection	12271934
33053213	33053236	9	+	28162770	OCIAML2	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-3.231442161362735	[121]	[71]	-9	hSpCas9	negative selection	12271935
33053146	33053169	9	-	28162770	OCIAML3	viability	GTGCAACAGATCAAACACGGTGG	SMU1	ENSG00000122692	-2.972519263577893	[25]	[9]	-9	hSpCas9	negative selection	12441292
33071830	33071853	9	+	28162770	OCIAML3	viability	AGTCTGTCTCAAAAGTGACCTGG	SMU1	ENSG00000122692	-1.6523062808888302	[100]	[96]	-8	hSpCas9	negative selection	12441293
33056945	33056968	9	-	28162770	OCIAML3	viability	AAGGTGTGGAAGATTCAGAGTGG	SMU1	ENSG00000122692	-1.5940076403241632	[59]	[59]	-8	hSpCas9	negative selection	12441294
33053229	33053252	9	-	28162770	OCIAML3	viability	AAATCCCTGGGCAGCACCGCAGG	SMU1	ENSG00000122692	-2.8164000616606115	[13]	[5]	-9	hSpCas9	negative selection	12441295
33060563	33060586	9	-	28162770	OCIAML3	viability	GTTTGGTCAGAAATCACATGTGG	SMU1	ENSG00000122692	-0.3142944933437386	[214]	[521]	-2	hSpCas9	negative selection	12441296
33056110	33056133	9	+	28162770	OCIAML3	viability	AACCTTTACAGTGCCATCAGAGG	SMU1	ENSG00000122692	-0.974611642539133	[68]	[105]	-6	hSpCas9	negative selection	12441297
33053122	33053145	9	-	28162770	OCIAML3	viability	CATCATGAACATGCAGGGGCAGG	SMU1	ENSG00000122692	-1.572312569224844	[65]	[66]	-8	hSpCas9	negative selection	12441298
33073709	33073732	9	-	28162770	OCIAML3	viability	TACTGTGTCTCTGAATACTGTGG	SMU1	ENSG00000122692	-3.9674660358516074	[56]	[10]	-9	hSpCas9	negative selection	12441299
33056195	33056218	9	-	28162770	OCIAML3	viability	AAAACCCTGAAGGAATTTCGTGG	SMU1	ENSG00000122692	-2.594007640324163	[1]	[0]	-9	hSpCas9	negative selection	12441300
33053213	33053236	9	+	28162770	OCIAML3	viability	GACGGTAATATCTGTCCCTGCGG	SMU1	ENSG00000122692	-1.6592252997706438	[180]	[172]	-8	hSpCas9	negative selection	12441301