Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6667
• Symbol:Sp1
• Description:Sp1 transcription factor

DataSource: http://genomecrispr.dkfz.de/#!/results/Sp1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
53406690	53406713	12	+	26472758	Jiyoye	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	0.3140659771143919	[15]	[14]	2	hSpCas9	negative selection	153887
53383180	53383203	12	-	26472758	Jiyoye	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-0.5928246184941266	[57]	[28]	-4	hSpCas9	negative selection	153888
53382173	53382196	12	+	26472758	Jiyoye	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-0.5206748327382914	[155]	[81]	-4	hSpCas9	negative selection	153889
53382359	53382382	12	+	26472758	Jiyoye	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-0.6259914824293258	[439]	[214]	-4	hSpCas9	negative selection	153890
53383296	53383319	12	+	26472758	Jiyoye	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	0.44465008692453634	[189]	[194]	3	hSpCas9	negative selection	153891
53381781	53381804	12	+	26472758	Jiyoye	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-1.3221770285504575	[62]	[18]	-7	hSpCas9	negative selection	153892
53382590	53382613	12	+	26472758	Jiyoye	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-1.2517877006590599	[299]	[94]	-7	hSpCas9	negative selection	153893
53382935	53382958	12	+	26472758	Jiyoye	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.5520057138860814	[452]	[232]	-4	hSpCas9	negative selection	153894
53382999	53383022	12	+	26472758	Jiyoye	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.3605062328736478	[268]	[157]	-3	hSpCas9	negative selection	153895
53383058	53383081	12	+	26472758	Jiyoye	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-2.708301835914063	[25]	[2]	-9	hSpCas9	negative selection	153896
53406690	53406713	12	+	26472758	KBM7	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	0.30750842170863235	[123,32]	[48,37]	3	hSpCas9	negative selection	345005
53383180	53383203	12	-	26472758	KBM7	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-0.7687696269663283	[465,417]	[38,195]	-6	hSpCas9	negative selection	345006
53382173	53382196	12	+	26472758	KBM7	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-1.877788473950433	[600,519]	[70,71]	-8	hSpCas9	negative selection	345007
53382359	53382382	12	+	26472758	KBM7	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-0.4657072543561934	[1398,1023]	[455,364]	-4	hSpCas9	negative selection	345008
53383296	53383319	12	+	26472758	KBM7	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-0.7300206230586259	[1520,1202]	[470,304]	-6	hSpCas9	negative selection	345009
53381781	53381804	12	+	26472758	KBM7	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-1.318629414534533	[241,203]	[81,5]	-7	hSpCas9	negative selection	345010
53382590	53382613	12	+	26472758	KBM7	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.199266372870877	[1240,1369]	[625,462]	-2	hSpCas9	negative selection	345011
53382935	53382958	12	+	26472758	KBM7	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	0.028020361464757837	[1642,1476]	[672,813]	0	hSpCas9	negative selection	345012
53382999	53383022	12	+	26472758	KBM7	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	0.35380189959979524	[883,620]	[478,416]	4	hSpCas9	negative selection	345013
53383058	53383081	12	+	26472758	KBM7	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-0.3498440034633692	[89,97]	[34,34]	-3	hSpCas9	negative selection	345014
53406690	53406713	12	+	26472758	Raji	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	-0.2383913014681307	[60]	[11]	-2	hSpCas9	negative selection	536123
53383180	53383203	12	-	26472758	Raji	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-0.8786772736685269	[205]	[25]	-6	hSpCas9	negative selection	536124
53382173	53382196	12	+	26472758	Raji	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	0.14055039930879878	[214]	[54]	1	hSpCas9	negative selection	536125
53382359	53382382	12	+	26472758	Raji	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	0.16121295210326947	[604]	[156]	1	hSpCas9	negative selection	536126
53383296	53383319	12	+	26472758	Raji	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	0.5688803457451037	[824]	[283]	5	hSpCas9	negative selection	536127
53381781	53381804	12	+	26472758	Raji	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-0.7467655981629455	[93]	[12]	-5	hSpCas9	negative selection	536128
53382590	53382613	12	+	26472758	Raji	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	0.36879784553923134	[593]	[177]	3	hSpCas9	negative selection	536129
53382935	53382958	12	+	26472758	Raji	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	1.0318325023664228	[587]	[278]	8	hSpCas9	negative selection	536130
53382999	53383022	12	+	26472758	Raji	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	0.24693488777239314	[511]	[140]	2	hSpCas9	negative selection	536131
53383058	53383081	12	+	26472758	Raji	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	0.9438848030907201	[55]	[24]	8	hSpCas9	negative selection	536132
53406690	53406713	12	+	26472758	K562	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	-2.843044113583893	[67]	[7]	-8	hSpCas9	negative selection	727241
53383180	53383203	12	-	26472758	K562	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-0.508488410368781	[272]	[161]	-3	hSpCas9	negative selection	727242
53382173	53382196	12	+	26472758	K562	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-0.7935945982702846	[422]	[205]	-5	hSpCas9	negative selection	727243
53382359	53382382	12	+	26472758	K562	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-1.0635925868857308	[1237]	[499]	-5	hSpCas9	negative selection	727244
53383296	53383319	12	+	26472758	K562	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-0.35930470116337077	[1160]	[763]	-2	hSpCas9	negative selection	727245
53381781	53381804	12	+	26472758	K562	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-7.732861195833469	[251]	[0]	-9	hSpCas9	negative selection	727246
53382590	53382613	12	+	26472758	K562	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.3248543990027366	[1005]	[677]	-2	hSpCas9	negative selection	727247
53382935	53382958	12	+	26472758	K562	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.9443074717841276	[1312]	[575]	-5	hSpCas9	negative selection	727248
53382999	53383022	12	+	26472758	K562	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.9754884302804067	[579]	[248]	-5	hSpCas9	negative selection	727249
53383058	53383081	12	+	26472758	K562	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-0.9779736936700014	[76]	[32]	-5	hSpCas9	negative selection	727250
53381752	53381775	12	-	26627737	DLD1	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.33404458410718957	[271]	[88,123,108]	3	hSpCas9	negative selection	784388
53382233	53382256	12	+	26627737	DLD1	viability	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-0.41670017926037645	[638]	[209,114,125]	-4	hSpCas9	negative selection	784389
53383150	53383173	12	+	26627737	DLD1	viability	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	0.35175950788688615	[744]	[454,223,220]	3	hSpCas9	negative selection	784390
53406632	53406655	12	+	26627737	DLD1	viability	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	0.3121118780866756	[419]	[66,283,145]	3	hSpCas9	negative selection	784391
53409493	53409516	12	-	26627737	DLD1	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.25860078181323226	[355]	[131,44,98]	-3	hSpCas9	negative selection	784392
53411177	53411200	12	+	26627737	DLD1	viability	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	0.45689214290252933	[310]	[169,143,92]	5	hSpCas9	negative selection	784393
53381752	53381775	12	-	26627737	GBM cells	viability after 5 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.6538013770491542	[191]	[148,174]	8	hSpCas9	negative selection	866703
53382233	53382256	12	+	26627737	GBM cells	viability after 5 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	1.003782992739641	[251]	[250,290]	9	hSpCas9	negative selection	866704
53383150	53383173	12	+	26627737	GBM cells	viability after 5 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	0.1376553674175356	[538]	[299,335]	2	hSpCas9	negative selection	866705
53406632	53406655	12	+	26627737	GBM cells	viability after 5 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	0.18741896823559767	[130]	[67,91]	3	hSpCas9	negative selection	866706
53409493	53409516	12	-	26627737	GBM cells	viability after 5 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.7748578927933264	[200]	[76,48]	-8	hSpCas9	negative selection	866707
53411177	53411200	12	+	26627737	GBM cells	viability after 5 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.3425067178420456	[317]	[166,101]	-5	hSpCas9	negative selection	866708
53381752	53381775	12	-	26627737	GBM cells	viability after 13 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.8172970678244069	[191]	[214,157]	8	hSpCas9	negative selection	949018
53382233	53382256	12	+	26627737	GBM cells	viability after 13 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.8509124124752374	[251]	[298,203]	8	hSpCas9	negative selection	949019
53383150	53383173	12	+	26627737	GBM cells	viability after 13 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-0.11369128111047089	[538]	[368,189]	-1	hSpCas9	negative selection	949020
53406632	53406655	12	+	26627737	GBM cells	viability after 13 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-0.1513198779590028	[130]	[63,63]	-2	hSpCas9	negative selection	949021
53409493	53409516	12	-	26627737	GBM cells	viability after 13 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	0.403331854839961	[200]	[205,93]	5	hSpCas9	negative selection	949022
53411177	53411200	12	+	26627737	GBM cells	viability after 13 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.10812261753400981	[317]	[185,138]	-1	hSpCas9	negative selection	949023
53381752	53381775	12	-	26627737	GBM cells	viability after 21 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	1.1332140407855293	[191]	[256,202]	9	hSpCas9	negative selection	1031333
53382233	53382256	12	+	26627737	GBM cells	viability after 21 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.7772175512030864	[251]	[254,215]	7	hSpCas9	negative selection	1031334
53383150	53383173	12	+	26627737	GBM cells	viability after 21 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	0.3177127316422781	[538]	[400,331]	3	hSpCas9	negative selection	1031335
53406632	53406655	12	+	26627737	GBM cells	viability after 21 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-0.12319702308953451	[130]	[68,61]	-1	hSpCas9	negative selection	1031336
53409493	53409516	12	-	26627737	GBM cells	viability after 21 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	0.45339771412168783	[200]	[148,149]	4	hSpCas9	negative selection	1031337
53411177	53411200	12	+	26627737	GBM cells	viability after 21 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.21973451263577287	[317]	[139,155]	-2	hSpCas9	negative selection	1031338
53381752	53381775	12	-	26627737	RPE1	viability after 9 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.5644050368079494	[1214]	[213,312]	-4	hSpCas9	negative selection	1113648
53382233	53382256	12	+	26627737	RPE1	viability after 9 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-1.6832188098075531	[2368]	[295,146]	-8	hSpCas9	negative selection	1113649
53383150	53383173	12	+	26627737	RPE1	viability after 9 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	0.3962105686483078	[841]	[273,440]	2	hSpCas9	negative selection	1113650
53406632	53406655	12	+	26627737	RPE1	viability after 9 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-0.003191563408978082	[480]	[89,227]	0	hSpCas9	negative selection	1113651
53409493	53409516	12	-	26627737	RPE1	viability after 9 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	0.8079402994713658	[655]	[321,407]	5	hSpCas9	negative selection	1113652
53411177	53411200	12	+	26627737	RPE1	viability after 9 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-1.0246492545949462	[1210]	[174,200]	-6	hSpCas9	negative selection	1113653
53381752	53381775	12	-	26627737	RPE1	viability after 12 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.2825419099051456	[1214]	[246,290]	-2	hSpCas9	negative selection	1195963
53382233	53382256	12	+	26627737	RPE1	viability after 12 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-1.3813566574561935	[2368]	[271,214]	-7	hSpCas9	negative selection	1195964
53383150	53383173	12	+	26627737	RPE1	viability after 12 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	0.48182435593208256	[841]	[227,408]	3	hSpCas9	negative selection	1195965
53406632	53406655	12	+	26627737	RPE1	viability after 12 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-0.36539840816111546	[480]	[110,88]	-2	hSpCas9	negative selection	1195966
53409493	53409516	12	-	26627737	RPE1	viability after 12 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	0.5161664352023052	[655]	[253,249]	3	hSpCas9	negative selection	1195967
53411177	53411200	12	+	26627737	RPE1	viability after 12 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.7527741198023558	[1210]	[195,189]	-5	hSpCas9	negative selection	1195968
53381752	53381775	12	-	26627737	RPE1	viability after 15 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-1.2869458456355871	[1214]	[120,159]	-7	hSpCas9	negative selection	1278278
53382233	53382256	12	+	26627737	RPE1	viability after 15 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-1.2787724624713395	[2368]	[433,123]	-7	hSpCas9	negative selection	1278279
53383150	53383173	12	+	26627737	RPE1	viability after 15 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	0.996913994426476	[841]	[511,439]	6	hSpCas9	negative selection	1278280
53406632	53406655	12	+	26627737	RPE1	viability after 15 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-0.7773566726159853	[480]	[113,45]	-5	hSpCas9	negative selection	1278281
53409493	53409516	12	-	26627737	RPE1	viability after 15 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	0.474968608689208	[655]	[149,361]	3	hSpCas9	negative selection	1278282
53411177	53411200	12	+	26627737	RPE1	viability after 15 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.4351650938877254	[1210]	[260,245]	-3	hSpCas9	negative selection	1278283
53381752	53381775	12	-	26627737	RPE1	viability after 18 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.6231333371557813	[1214]	[194,231]	-4	hSpCas9	negative selection	1360593
53382233	53382256	12	+	26627737	RPE1	viability after 18 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-1.1930660778227455	[2368]	[355,197]	-6	hSpCas9	negative selection	1360594
53383150	53383173	12	+	26627737	RPE1	viability after 18 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	1.038362539715929	[841]	[428,506]	6	hSpCas9	negative selection	1360595
53406632	53406655	12	+	26627737	RPE1	viability after 18 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-0.25650111811433884	[480]	[127,87]	-2	hSpCas9	negative selection	1360596
53409493	53409516	12	-	26627737	RPE1	viability after 18 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	0.9008812950739142	[655]	[273,390]	5	hSpCas9	negative selection	1360597
53411177	53411200	12	+	26627737	RPE1	viability after 18 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.29541397397650215	[1210]	[274,256]	-2	hSpCas9	negative selection	1360598
53381752	53381775	12	-	26627737	HeLa	viability after 8 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.8035838261155859	[217]	[241,186,89]	6	hSpCas9	negative selection	1442908
53382233	53382256	12	+	26627737	HeLa	viability after 8 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	1.3063561650477467	[230]	[288,221,243]	8	hSpCas9	negative selection	1442909
53383150	53383173	12	+	26627737	HeLa	viability after 8 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-0.6799217453025587	[707]	[220,62,291]	-6	hSpCas9	negative selection	1442910
53406632	53406655	12	+	26627737	HeLa	viability after 8 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-1.8364278615831462	[663]	[66,7,158]	-9	hSpCas9	negative selection	1442911
53409493	53409516	12	-	26627737	HeLa	viability after 8 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.7266903082170394	[246]	[37,27,118]	-6	hSpCas9	negative selection	1442912
53411177	53411200	12	+	26627737	HeLa	viability after 8 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-1.050630159399655	[654]	[113,176,117]	-8	hSpCas9	negative selection	1442913
53381752	53381775	12	-	26627737	HeLa	viability after 12 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.37222027800316	[217]	[150,114,84]	3	hSpCas9	negative selection	1525223
53382233	53382256	12	+	26627737	HeLa	viability after 12 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.815847368947613	[230]	[260,109,141]	6	hSpCas9	negative selection	1525224
53383150	53383173	12	+	26627737	HeLa	viability after 12 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-0.19358333630764557	[707]	[265,244,257]	-2	hSpCas9	negative selection	1525225
53406632	53406655	12	+	26627737	HeLa	viability after 12 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-1.4494651204032927	[663]	[180,69,55]	-8	hSpCas9	negative selection	1525226
53409493	53409516	12	-	26627737	HeLa	viability after 12 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.013279385723077741	[246]	[147,117,36]	0	hSpCas9	negative selection	1525227
53411177	53411200	12	+	26627737	HeLa	viability after 12 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-1.1864208945563384	[654]	[140,160,50]	-8	hSpCas9	negative selection	1525228
53381752	53381775	12	-	26627737	HeLa	viability after 15 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.768719841456616	[217]	[180,147,121]	6	hSpCas9	negative selection	1607538
53382233	53382256	12	+	26627737	HeLa	viability after 15 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.8690609528291753	[230]	[82,278,152]	6	hSpCas9	negative selection	1607539
53383150	53383173	12	+	26627737	HeLa	viability after 15 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-0.44788311066675535	[707]	[255,145,232]	-4	hSpCas9	negative selection	1607540
53406632	53406655	12	+	26627737	HeLa	viability after 15 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-1.7311039765159622	[663]	[107,101,29]	-9	hSpCas9	negative selection	1607541
53409493	53409516	12	-	26627737	HeLa	viability after 15 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	0.06343298721141033	[246]	[115,94,103]	0	hSpCas9	negative selection	1607542
53411177	53411200	12	+	26627737	HeLa	viability after 15 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.19591999371664381	[654]	[357,247,78]	-2	hSpCas9	negative selection	1607543
53381752	53381775	12	-	26627737	HeLa	viability after 18 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.77223070237463	[217]	[124,118,121]	6	hSpCas9	negative selection	1689853
53382233	53382256	12	+	26627737	HeLa	viability after 18 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.876358979227738	[230]	[50,238,152]	6	hSpCas9	negative selection	1689854
53383150	53383173	12	+	26627737	HeLa	viability after 18 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-0.48298969572851913	[707]	[164,116,232]	-4	hSpCas9	negative selection	1689855
53406632	53406655	12	+	26627737	HeLa	viability after 18 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-1.7313899773928192	[663]	[71,84,29]	-9	hSpCas9	negative selection	1689856
53409493	53409516	12	-	26627737	HeLa	viability after 18 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	0.058042838293639654	[246]	[79,74,103]	0	hSpCas9	negative selection	1689857
53411177	53411200	12	+	26627737	HeLa	viability after 18 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.1803503096301705	[654]	[238,212,78]	-1	hSpCas9	negative selection	1689858
53381752	53381775	12	-	26627737	HCT116	viability after 6 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.6085570528756503	[293]	[19,35]	-3	hSpCas9	negative selection	1772168
53382233	53382256	12	+	26627737	HCT116	viability after 6 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-0.4912394444805205	[952]	[210,48]	-3	hSpCas9	negative selection	1772169
53383150	53383173	12	+	26627737	HCT116	viability after 6 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	0.3450325672383381	[978]	[199,192]	2	hSpCas9	negative selection	1772170
53406632	53406655	12	+	26627737	HCT116	viability after 6 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	0.7338516545102788	[253]	[155,16]	4	hSpCas9	negative selection	1772171
53409493	53409516	12	-	26627737	HCT116	viability after 6 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	2.0913029339857356	[295]	[31,289]	8	hSpCas9	negative selection	1772172
53411177	53411200	12	+	26627737	HCT116	viability after 6 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	1.5634370083614915	[675]	[141,408]	7	hSpCas9	negative selection	1772173
53381752	53381775	12	-	26627737	HCT116	viability after 8 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.31493053753498457	[229]	[82,94,126]	-4	hSpCas9	negative selection	1854483
53382233	53382256	12	+	26627737	HCT116	viability after 8 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.20738537175625463	[249]	[167,123,184]	2	hSpCas9	negative selection	1854484
53383150	53383173	12	+	26627737	HCT116	viability after 8 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-0.5503113790673302	[647]	[243,202,283]	-6	hSpCas9	negative selection	1854485
53406632	53406655	12	+	26627737	HCT116	viability after 8 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	1.0633428599254173	[64]	[64,53,104]	8	hSpCas9	negative selection	1854486
53409493	53409516	12	-	26627737	HCT116	viability after 8 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.4432790607104694	[190]	[80,50,99]	-5	hSpCas9	negative selection	1854487
53411177	53411200	12	+	26627737	HCT116	viability after 8 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.05066758817113928	[341]	[252,102,190]	0	hSpCas9	negative selection	1854488
53381752	53381775	12	-	26627737	HCT116	viability after 9 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	1.2368394310304973	[293]	[160,203]	7	hSpCas9	negative selection	1936798
53382233	53382256	12	+	26627737	HCT116	viability after 9 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.08055455679561274	[952]	[439,133]	0	hSpCas9	negative selection	1936799
53383150	53383173	12	+	26627737	HCT116	viability after 9 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	0.8972023422235491	[978]	[387,564]	6	hSpCas9	negative selection	1936800
53406632	53406655	12	+	26627737	HCT116	viability after 9 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-1.4895552377862422	[253]	[36,13]	-8	hSpCas9	negative selection	1936801
53409493	53409516	12	-	26627737	HCT116	viability after 9 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.8453273579881238	[295]	[86,9]	-5	hSpCas9	negative selection	1936802
53411177	53411200	12	+	26627737	HCT116	viability after 9 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.3053530635464546	[675]	[235,74]	-2	hSpCas9	negative selection	1936803
53381752	53381775	12	-	26627737	HCT116	viability after 12 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.3972971379205805	[229]	[59,86,130]	-4	hSpCas9	negative selection	2019113
53382233	53382256	12	+	26627737	HCT116	viability after 12 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-0.3144330792183829	[249]	[112,133,69]	-3	hSpCas9	negative selection	2019114
53383150	53383173	12	+	26627737	HCT116	viability after 12 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-0.8868460554260997	[647]	[204,156,187]	-7	hSpCas9	negative selection	2019115
53406632	53406655	12	+	26627737	HCT116	viability after 12 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	0.6977936699724527	[64]	[19,82,66]	6	hSpCas9	negative selection	2019116
53409493	53409516	12	-	26627737	HCT116	viability after 12 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.5276269438843179	[190]	[75,55,75]	-5	hSpCas9	negative selection	2019117
53411177	53411200	12	+	26627737	HCT116	viability after 12 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	0.307006330991378	[341]	[173,209,286]	3	hSpCas9	negative selection	2019118
53381752	53381775	12	-	26627737	HCT116	viability after 15 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.8000371129632192	[229]	[95,54,78]	-7	hSpCas9	negative selection	2101428
53382233	53382256	12	+	26627737	HCT116	viability after 15 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-0.4407063190499745	[249]	[113,69,133]	-4	hSpCas9	negative selection	2101429
53383150	53383173	12	+	26627737	HCT116	viability after 15 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-0.36868780140948276	[647]	[291,357,215]	-4	hSpCas9	negative selection	2101430
53406632	53406655	12	+	26627737	HCT116	viability after 15 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	0.9621034099554229	[64]	[38,96,77]	7	hSpCas9	negative selection	2101431
53409493	53409516	12	-	26627737	HCT116	viability after 15 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.3720679826800256	[190]	[79,114,58]	-4	hSpCas9	negative selection	2101432
53411177	53411200	12	+	26627737	HCT116	viability after 15 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	0.5888670423914419	[341]	[226,279,369]	5	hSpCas9	negative selection	2101433
53381752	53381775	12	-	26627737	HCT116	viability after 18 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.9531778070070255	[229]	[40,40,92]	-7	hSpCas9	negative selection	2183743
53382233	53382256	12	+	26627737	HCT116	viability after 18 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.10673179569947797	[249]	[47,158,183]	0	hSpCas9	negative selection	2183744
53383150	53383173	12	+	26627737	HCT116	viability after 18 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-0.6742890004984357	[647]	[166,164,261]	-6	hSpCas9	negative selection	2183745
53406632	53406655	12	+	26627737	HCT116	viability after 18 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	1.5389840375496973	[64]	[4,151,113]	9	hSpCas9	negative selection	2183746
53409493	53409516	12	-	26627737	HCT116	viability after 18 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-1.1912462019200114	[190]	[14,44,61]	-8	hSpCas9	negative selection	2183747
53411177	53411200	12	+	26627737	HCT116	viability after 18 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	0.21896636101240669	[341]	[189,101,295]	2	hSpCas9	negative selection	2183748
53381671	53381694	12	-	24336569	HL60	viability	CACAGCTGTCATTTCATCCATGG	SP1	ENSG00000185591	0.5157767298706967	[194]	[589]	4	hSpCas9	negative selection	2296721
53381706	53381729	12	+	24336569	HL60	viability	AAAGGAGTTGGTGGCAATAATGG	SP1	ENSG00000185591	0.03975893997149893	[558]	[1215]	0	hSpCas9	negative selection	2296722
53381760	53381783	12	+	24336569	HL60	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.3665810045409635	[473]	[777]	-3	hSpCas9	negative selection	2296723
53381778	53381801	12	+	24336569	HL60	viability	ACAGGCAGTAGCAGCAGCACTGG	SP1	ENSG00000185591	-0.3193115130521116	[828]	[1405]	-3	hSpCas9	negative selection	2296724
53381784	53381807	12	+	24336569	HL60	viability	AGTAGCAGCAGCACTGGAGGAGG	SP1	ENSG00000185591	-0.6672346075548133	[892]	[1189]	-6	hSpCas9	negative selection	2296725
53381792	53381815	12	+	24336569	HL60	viability	CAGCACTGGAGGAGGAGGGCAGG	SP1	ENSG00000185591	-0.009139262389573855	[1205]	[2535]	0	hSpCas9	negative selection	2296726
53382242	53382265	12	+	24336569	HL60	viability	CAACTTTCACAGGGTGCCAATGG	SP1	ENSG00000185591	0.7236729961788888	[92]	[324]	6	hSpCas9	negative selection	2296727
53382258	53382281	12	-	24336569	HL60	viability	AGAGATGATCTGCCAGCCATTGG	SP1	ENSG00000185591	-0.1086102426420192	[455]	[894]	-1	hSpCas9	negative selection	2296728
53382269	53382292	12	+	24336569	HL60	viability	CAGATCATCTCTTCCTCCTCTGG	SP1	ENSG00000185591	-0.9547069583429573	[97]	[106]	-7	hSpCas9	negative selection	2296729
53382298	53382321	12	-	24336569	HL60	viability	CACTCTGTTCCTTTGAGGTAGGG	SP1	ENSG00000185591	-0.87501322316147	[363]	[419]	-7	hSpCas9	negative selection	2296730
53381671	53381694	12	-	24336569	KBM7	viability	CACAGCTGTCATTTCATCCATGG	SP1	ENSG00000185591	-1.1200045385203783	[407]	[511]	-7	hSpCas9	negative selection	2363898
53381706	53381729	12	+	24336569	KBM7	viability	AAAGGAGTTGGTGGCAATAATGG	SP1	ENSG00000185591	0.9634227894948046	[536]	[2855]	8	hSpCas9	negative selection	2363899
53381760	53381783	12	+	24336569	KBM7	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.4674998906721427	[473]	[934]	-4	hSpCas9	negative selection	2363900
53381778	53381801	12	+	24336569	KBM7	viability	ACAGGCAGTAGCAGCAGCACTGG	SP1	ENSG00000185591	-0.7457454738426792	[556]	[905]	-5	hSpCas9	negative selection	2363901
53381784	53381807	12	+	24336569	KBM7	viability	AGTAGCAGCAGCACTGGAGGAGG	SP1	ENSG00000185591	-2.1164641808151297	[813]	[511]	-8	hSpCas9	negative selection	2363902
53381792	53381815	12	+	24336569	KBM7	viability	CAGCACTGGAGGAGGAGGGCAGG	SP1	ENSG00000185591	-1.2689260666418507	[1061]	[1201]	-7	hSpCas9	negative selection	2363903
53382242	53382265	12	+	24336569	KBM7	viability	CAACTTTCACAGGGTGCCAATGG	SP1	ENSG00000185591	1.2911886402513089	[39]	[266]	9	hSpCas9	negative selection	2363904
53382258	53382281	12	-	24336569	KBM7	viability	AGAGATGATCTGCCAGCCATTGG	SP1	ENSG00000185591	-1.3482927146456882	[771]	[826]	-7	hSpCas9	negative selection	2363905
53382269	53382292	12	+	24336569	KBM7	viability	CAGATCATCTCTTCCTCCTCTGG	SP1	ENSG00000185591	1.9447382262298776	[53]	[566]	9	hSpCas9	negative selection	2363906
53382298	53382321	12	-	24336569	KBM7	viability	CACTCTGTTCCTTTGAGGTAGGG	SP1	ENSG00000185591	-0.8180265448036558	[222]	[344]	-6	hSpCas9	negative selection	2363907
53404129	53404152	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCGCCCAGGCTGAAGTGCAGTAG	SP1	ENSG00000185591	0.5659162618008384	[5,27]	[7,1]	2	dCas9-VP64	positive selection	2391383
53409819	53409842	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGACGGGGTTTCACCATGTTAG	SP1	ENSG00000185591	1.7100356304154607	[4,2]	[3,0]	6	dCas9-VP64	positive selection	2409613
53384155	53384178	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGACGGGGTTTCACCATGTGAG	SP1	ENSG00000185591	1.7100356304154607	[4,2]	[3,0]	6	dCas9-VP64	positive selection	2409673
53380443	53380466	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGGGAGGGAGACGGGGCAGTGG	SP1	ENSG00000185591	-0.41280773592826825	[95,6]	[13,1]	-2	dCas9-VP64	positive selection	2432086
53380485	53380508	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGATGGGCCGCCCGCCCCGGG	SP1	ENSG00000185591	-1.0742283581320975	[68,133]	[8,10]	-6	dCas9-VP64	positive selection	2432087
53380550	53380573	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTAAGGCCCGTCCCCCGTGG	SP1	ENSG00000185591	0.024697042093238863	[10,11]	[1,1]	0	dCas9-VP64	positive selection	2432088
53392848	53392871	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGGTCTCTCTCTGTCGCCCAGG	SP1	ENSG00000185591	0.02530895549556833	[184,294]	[44,62]	0	dCas9-VP64	positive selection	2440956
53401405	53401428	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGCCATTGCACTCCAGCCTGG	SP1	ENSG00000185591	0.6055497745369944	[158,1336]	[33,490]	2	dCas9-VP64	positive selection	2451273
53404129	53404152	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCGCCCAGGCTGAAGTGCAGTAG	SP1	ENSG00000185591	-0.6364032269027842	[259,84]	[25,45]	-6	dCas9-VP64	positive selection	2486638
53409819	53409842	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGACGGGGTTTCACCATGTTAG	SP1	ENSG00000185591	-0.28524240662887035	[88,68]	[26,14]	-3	dCas9-VP64	positive selection	2504868
53384155	53384178	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGACGGGGTTTCACCATGTGAG	SP1	ENSG00000185591	-0.28524240662887035	[88,68]	[26,14]	-3	dCas9-VP64	positive selection	2504928
53380443	53380466	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGGGAGGGAGACGGGGCAGTGG	SP1	ENSG00000185591	2.0799952009707137	[155,157]	[19,401]	8	dCas9-VP64	positive selection	2527341
53380485	53380508	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGATGGGCCGCCCGCCCCGGG	SP1	ENSG00000185591	-0.28865291161119255	[304,49]	[77,19]	-3	dCas9-VP64	positive selection	2527342
53380550	53380573	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTAAGGCCCGTCCCCCGTGG	SP1	ENSG00000185591	-0.6082068906908478	[70,9]	[12,3]	-6	dCas9-VP64	positive selection	2527343
53392848	53392871	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGGTCTCTCTCTGTCGCCCAGG	SP1	ENSG00000185591	0.2910810520059125	[117,112]	[36,54]	2	dCas9-VP64	positive selection	2536211
53401405	53401428	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGCCATTGCACTCCAGCCTGG	SP1	ENSG00000185591	0.3847800892193698	[535,417]	[146,256]	3	dCas9-VP64	positive selection	2546528
53381784	53381807	12	+	27260157	DLD1	viability	AGTAGCAGCAGCACTGGAGGAGG	SP1	ENSG00000185591	-0.112205446544171	[]	[]	-1	hSpCas9	negative selection	2574682
53382258	53382281	12	-	27260157	DLD1	viability	AGAGATGATCTGCCAGCCATTGG	SP1	ENSG00000185591	1.25674445985013	[]	[]	9	hSpCas9	negative selection	2578891
53382298	53382321	12	-	27260157	DLD1	viability	CACTCTGTTCCTTTGAGGTAGGG	SP1	ENSG00000185591	0.128640732507314	[]	[]	3	hSpCas9	negative selection	2578989
53382708	53382731	12	-	27260157	DLD1	viability	ATTCAGGGCCACTGGTACATTGG	SP1	ENSG00000185591	-0.0455720686373541	[]	[]	0	hSpCas9	negative selection	2580911
53380287	53380310	12	-	27260157	DLD1	viability	CTCATCCTTACCGCTCATGGTGG	SP1	ENSG00000185591	-0.604344962682812	[]	[]	-5	hSpCas9	negative selection	2581873
53382269	53382292	12	+	27260157	DLD1	viability	CAGATCATCTCTTCCTCCTCTGG	SP1	ENSG00000185591	0.41890360374845	[]	[]	7	hSpCas9	negative selection	2582217
53382418	53382441	12	-	27260157	DLD1	viability	GTAGTCCTGTCAGAACTTGCTGG	SP1	ENSG00000185591	-0.70685198748404	[]	[]	-5	hSpCas9	negative selection	2587018
53383015	53383038	12	+	27260157	DLD1	viability	CCAGAGGGTCAGTGGGCTACAGG	SP1	ENSG00000185591	-0.360019828846325	[]	[]	-3	hSpCas9	negative selection	2607530
53381706	53381729	12	+	27260157	DLD1	viability	AAAGGAGTTGGTGGCAATAATGG	SP1	ENSG00000185591	-0.495774204207651	[]	[]	-4	hSpCas9	negative selection	2608590
53383281	53383304	12	+	27260157	DLD1	viability	ACTCTGGTCCCATCATCATCCGG	SP1	ENSG00000185591	-0.438217117361951	[]	[]	-4	hSpCas9	negative selection	2609658
53381671	53381694	12	-	27260157	DLD1	viability	CACAGCTGTCATTTCATCCATGG	SP1	ENSG00000185591	-0.580854184760043	[]	[]	-5	hSpCas9	negative selection	2614045
53381752	53381775	12	-	27260157	DLD1	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.163686238589207	[]	[]	-1	hSpCas9	negative selection	2614310
53383189	53383212	12	-	27260157	DLD1	viability	CTGACAATGGTGCTGCTTGGAGG	SP1	ENSG00000185591	0.391081648692981	[]	[]	4	hSpCas9	negative selection	2620769
53381778	53381801	12	+	27260157	DLD1	viability	ACAGGCAGTAGCAGCAGCACTGG	SP1	ENSG00000185591	0.0182971258684705	[]	[]	0	hSpCas9	negative selection	2621219
53382242	53382265	12	+	27260157	DLD1	viability	CAACTTTCACAGGGTGCCAATGG	SP1	ENSG00000185591	0.112927874080231	[]	[]	3	hSpCas9	negative selection	2623969
53381760	53381783	12	+	27260157	DLD1	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.639625130832944	[]	[]	-5	hSpCas9	negative selection	2643872
53381792	53381815	12	+	27260157	DLD1	viability	CAGCACTGGAGGAGGAGGGCAGG	SP1	ENSG00000185591	-0.233602801617925	[]	[]	-2	hSpCas9	negative selection	2644302
53380652	53380675	12	-	27260157	DLD1	viability	ACCAGGCAGGCGGTTGGCCCGGG	SP1	ENSG00000185591	-0.32818802805924	[]	[]	-3	hSpCas9	negative selection	2644559
53382476	53382499	12	+	27260157	DLD1	viability	CCACAGTTCCAGACCGTTGATGG	SP1	ENSG00000185591	0.493395008550772	[]	[]	8	hSpCas9	negative selection	2644591
53382475	53382498	12	-	27260157	DLD1	viability	CATCAACGGTCTGGAACTGTGGG	SP1	ENSG00000185591	-0.177059157903323	[]	[]	-1	hSpCas9	negative selection	2648027
53381784	53381807	12	+	27260157	HT1080	viability	AGTAGCAGCAGCACTGGAGGAGG	SP1	ENSG00000185591	-0.888366355753965	[]	[]	-8	hSpCas9	negative selection	2650812
53382258	53382281	12	-	27260157	HT1080	viability	AGAGATGATCTGCCAGCCATTGG	SP1	ENSG00000185591	0.818662871523702	[]	[]	7	hSpCas9	negative selection	2655021
53382298	53382321	12	-	27260157	HT1080	viability	CACTCTGTTCCTTTGAGGTAGGG	SP1	ENSG00000185591	-0.367353649272216	[]	[]	-7	hSpCas9	negative selection	2655119
53382708	53382731	12	-	27260157	HT1080	viability	ATTCAGGGCCACTGGTACATTGG	SP1	ENSG00000185591	-0.324551561200552	[]	[]	-7	hSpCas9	negative selection	2657041
53380287	53380310	12	-	27260157	HT1080	viability	CTCATCCTTACCGCTCATGGTGG	SP1	ENSG00000185591	-0.44739794190786	[]	[]	-7	hSpCas9	negative selection	2658003
53382269	53382292	12	+	27260157	HT1080	viability	CAGATCATCTCTTCCTCCTCTGG	SP1	ENSG00000185591	0.765478977245863	[]	[]	6	hSpCas9	negative selection	2658347
53382418	53382441	12	-	27260157	HT1080	viability	GTAGTCCTGTCAGAACTTGCTGG	SP1	ENSG00000185591	0.119596916467635	[]	[]	1	hSpCas9	negative selection	2663148
53383015	53383038	12	+	27260157	HT1080	viability	CCAGAGGGTCAGTGGGCTACAGG	SP1	ENSG00000185591	0.4142882510495	[]	[]	4	hSpCas9	negative selection	2683660
53381706	53381729	12	+	27260157	HT1080	viability	AAAGGAGTTGGTGGCAATAATGG	SP1	ENSG00000185591	-0.116792211474494	[]	[]	0	hSpCas9	negative selection	2684720
53383281	53383304	12	+	27260157	HT1080	viability	ACTCTGGTCCCATCATCATCCGG	SP1	ENSG00000185591	-0.187411596219454	[]	[]	0	hSpCas9	negative selection	2685788
53381671	53381694	12	-	27260157	HT1080	viability	CACAGCTGTCATTTCATCCATGG	SP1	ENSG00000185591	-0.23983464289094	[]	[]	0	hSpCas9	negative selection	2690175
53381752	53381775	12	-	27260157	HT1080	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-1.68722765737574	[]	[]	-9	hSpCas9	negative selection	2690440
53383189	53383212	12	-	27260157	HT1080	viability	CTGACAATGGTGCTGCTTGGAGG	SP1	ENSG00000185591	-0.198098717032525	[]	[]	0	hSpCas9	negative selection	2696899
53381778	53381801	12	+	27260157	HT1080	viability	ACAGGCAGTAGCAGCAGCACTGG	SP1	ENSG00000185591	-0.223303407902589	[]	[]	0	hSpCas9	negative selection	2697349
53382242	53382265	12	+	27260157	HT1080	viability	CAACTTTCACAGGGTGCCAATGG	SP1	ENSG00000185591	0.150398509743222	[]	[]	1	hSpCas9	negative selection	2700099
53381760	53381783	12	+	27260157	HT1080	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-1.21816722349355	[]	[]	-8	hSpCas9	negative selection	2720002
53381792	53381815	12	+	27260157	HT1080	viability	CAGCACTGGAGGAGGAGGGCAGG	SP1	ENSG00000185591	0.0247720303731952	[]	[]	0	hSpCas9	negative selection	2720432
53380652	53380675	12	-	27260157	HT1080	viability	ACCAGGCAGGCGGTTGGCCCGGG	SP1	ENSG00000185591	0.334787317530762	[]	[]	3	hSpCas9	negative selection	2720689
53382476	53382499	12	+	27260157	HT1080	viability	CCACAGTTCCAGACCGTTGATGG	SP1	ENSG00000185591	0.389870549437388	[]	[]	3	hSpCas9	negative selection	2720721
53382475	53382498	12	-	27260157	HT1080	viability	CATCAACGGTCTGGAACTGTGGG	SP1	ENSG00000185591	-0.123878278946389	[]	[]	0	hSpCas9	negative selection	2724157
53381784	53381807	12	+	27260157	MKN45	viability	AGTAGCAGCAGCACTGGAGGAGG	SP1	ENSG00000185591	-1.89369941361591	[]	[]	-9	hSpCas9	negative selection	2726942
53382258	53382281	12	-	27260157	MKN45	viability	AGAGATGATCTGCCAGCCATTGG	SP1	ENSG00000185591	0.202971084170298	[]	[]	5	hSpCas9	negative selection	2731151
53382298	53382321	12	-	27260157	MKN45	viability	CACTCTGTTCCTTTGAGGTAGGG	SP1	ENSG00000185591	-0.975079392258173	[]	[]	-7	hSpCas9	negative selection	2731249
53382708	53382731	12	-	27260157	MKN45	viability	ATTCAGGGCCACTGGTACATTGG	SP1	ENSG00000185591	-1.15133359931295	[]	[]	-8	hSpCas9	negative selection	2733171
53380287	53380310	12	-	27260157	MKN45	viability	CTCATCCTTACCGCTCATGGTGG	SP1	ENSG00000185591	-0.366170324705904	[]	[]	-1	hSpCas9	negative selection	2734133
53382269	53382292	12	+	27260157	MKN45	viability	CAGATCATCTCTTCCTCCTCTGG	SP1	ENSG00000185591	0.504086396072438	[]	[]	6	hSpCas9	negative selection	2734477
53382418	53382441	12	-	27260157	MKN45	viability	GTAGTCCTGTCAGAACTTGCTGG	SP1	ENSG00000185591	-1.27160282263668	[]	[]	-8	hSpCas9	negative selection	2739278
53383015	53383038	12	+	27260157	MKN45	viability	CCAGAGGGTCAGTGGGCTACAGG	SP1	ENSG00000185591	0.67305787624645	[]	[]	7	hSpCas9	negative selection	2759790
53381706	53381729	12	+	27260157	MKN45	viability	AAAGGAGTTGGTGGCAATAATGG	SP1	ENSG00000185591	-0.826149556348506	[]	[]	-7	hSpCas9	negative selection	2760850
53383281	53383304	12	+	27260157	MKN45	viability	ACTCTGGTCCCATCATCATCCGG	SP1	ENSG00000185591	-1.17979661697503	[]	[]	-8	hSpCas9	negative selection	2761918
53381671	53381694	12	-	27260157	MKN45	viability	CACAGCTGTCATTTCATCCATGG	SP1	ENSG00000185591	-0.00557583723304098	[]	[]	0	hSpCas9	negative selection	2766305
53381752	53381775	12	-	27260157	MKN45	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-1.94380212909756	[]	[]	-9	hSpCas9	negative selection	2766570
53383189	53383212	12	-	27260157	MKN45	viability	CTGACAATGGTGCTGCTTGGAGG	SP1	ENSG00000185591	-0.118742655604736	[]	[]	0	hSpCas9	negative selection	2773029
53381778	53381801	12	+	27260157	MKN45	viability	ACAGGCAGTAGCAGCAGCACTGG	SP1	ENSG00000185591	-0.454499882068446	[]	[]	-6	hSpCas9	negative selection	2773479
53382242	53382265	12	+	27260157	MKN45	viability	CAACTTTCACAGGGTGCCAATGG	SP1	ENSG00000185591	-0.337471184534591	[]	[]	-1	hSpCas9	negative selection	2776229
53381760	53381783	12	+	27260157	MKN45	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.265260582638343	[]	[]	-1	hSpCas9	negative selection	2796132
53381792	53381815	12	+	27260157	MKN45	viability	CAGCACTGGAGGAGGAGGGCAGG	SP1	ENSG00000185591	0.0312241297746532	[]	[]	0	hSpCas9	negative selection	2796562
53380652	53380675	12	-	27260157	MKN45	viability	ACCAGGCAGGCGGTTGGCCCGGG	SP1	ENSG00000185591	-0.11547230847734	[]	[]	0	hSpCas9	negative selection	2796819
53382476	53382499	12	+	27260157	MKN45	viability	CCACAGTTCCAGACCGTTGATGG	SP1	ENSG00000185591	-0.317537126019455	[]	[]	-1	hSpCas9	negative selection	2796851
53382475	53382498	12	-	27260157	MKN45	viability	CATCAACGGTCTGGAACTGTGGG	SP1	ENSG00000185591	-0.979245485025029	[]	[]	-7	hSpCas9	negative selection	2800287
53381784	53381807	12	+	27260157	RKO	viability	AGTAGCAGCAGCACTGGAGGAGG	SP1	ENSG00000185591	-1.16262510583896	[]	[]	-8	hSpCas9	negative selection	2803072
53382258	53382281	12	-	27260157	RKO	viability	AGAGATGATCTGCCAGCCATTGG	SP1	ENSG00000185591	0.256496021721872	[]	[]	1	hSpCas9	negative selection	2807281
53382298	53382321	12	-	27260157	RKO	viability	CACTCTGTTCCTTTGAGGTAGGG	SP1	ENSG00000185591	-1.51001625524855	[]	[]	-8	hSpCas9	negative selection	2807379
53382708	53382731	12	-	27260157	RKO	viability	ATTCAGGGCCACTGGTACATTGG	SP1	ENSG00000185591	-1.01253067825328	[]	[]	-8	hSpCas9	negative selection	2809301
53380287	53380310	12	-	27260157	RKO	viability	CTCATCCTTACCGCTCATGGTGG	SP1	ENSG00000185591	-0.653574861470781	[]	[]	-7	hSpCas9	negative selection	2810263
53382269	53382292	12	+	27260157	RKO	viability	CAGATCATCTCTTCCTCCTCTGG	SP1	ENSG00000185591	0.190046283467229	[]	[]	1	hSpCas9	negative selection	2810607
53382418	53382441	12	-	27260157	RKO	viability	GTAGTCCTGTCAGAACTTGCTGG	SP1	ENSG00000185591	-0.119190479791508	[]	[]	0	hSpCas9	negative selection	2815408
53383015	53383038	12	+	27260157	RKO	viability	CCAGAGGGTCAGTGGGCTACAGG	SP1	ENSG00000185591	-0.733557966944985	[]	[]	-7	hSpCas9	negative selection	2835920
53381706	53381729	12	+	27260157	RKO	viability	AAAGGAGTTGGTGGCAATAATGG	SP1	ENSG00000185591	-0.478319959884429	[]	[]	-6	hSpCas9	negative selection	2836980
53383281	53383304	12	+	27260157	RKO	viability	ACTCTGGTCCCATCATCATCCGG	SP1	ENSG00000185591	-0.456675713505785	[]	[]	-6	hSpCas9	negative selection	2838048
53381671	53381694	12	-	27260157	RKO	viability	CACAGCTGTCATTTCATCCATGG	SP1	ENSG00000185591	-0.998594180256601	[]	[]	-8	hSpCas9	negative selection	2842435
53381752	53381775	12	-	27260157	RKO	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.907537073517797	[]	[]	-8	hSpCas9	negative selection	2842700
53383189	53383212	12	-	27260157	RKO	viability	CTGACAATGGTGCTGCTTGGAGG	SP1	ENSG00000185591	-0.856793652073625	[]	[]	-7	hSpCas9	negative selection	2849159
53381778	53381801	12	+	27260157	RKO	viability	ACAGGCAGTAGCAGCAGCACTGG	SP1	ENSG00000185591	-0.362382785742382	[]	[]	-6	hSpCas9	negative selection	2849609
53382242	53382265	12	+	27260157	RKO	viability	CAACTTTCACAGGGTGCCAATGG	SP1	ENSG00000185591	-0.369720079873241	[]	[]	-6	hSpCas9	negative selection	2852359
53381760	53381783	12	+	27260157	RKO	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.403325842032518	[]	[]	-6	hSpCas9	negative selection	2872262
53381792	53381815	12	+	27260157	RKO	viability	CAGCACTGGAGGAGGAGGGCAGG	SP1	ENSG00000185591	-0.395024254148673	[]	[]	-6	hSpCas9	negative selection	2872692
53380652	53380675	12	-	27260157	RKO	viability	ACCAGGCAGGCGGTTGGCCCGGG	SP1	ENSG00000185591	-0.232400728918726	[]	[]	-1	hSpCas9	negative selection	2872949
53382476	53382499	12	+	27260157	RKO	viability	CCACAGTTCCAGACCGTTGATGG	SP1	ENSG00000185591	0.0786882760985633	[]	[]	0	hSpCas9	negative selection	2872981
53382475	53382498	12	-	27260157	RKO	viability	CATCAACGGTCTGGAACTGTGGG	SP1	ENSG00000185591	0.0198215569827731	[]	[]	0	hSpCas9	negative selection	2876417
53381784	53381807	12	+	27260157	SF268	viability	AGTAGCAGCAGCACTGGAGGAGG	SP1	ENSG00000185591	-1.40129355088026	[]	[]	-8	hSpCas9	negative selection	2879202
53382258	53382281	12	-	27260157	SF268	viability	AGAGATGATCTGCCAGCCATTGG	SP1	ENSG00000185591	-0.135747241596961	[]	[]	-1	hSpCas9	negative selection	2883411
53382298	53382321	12	-	27260157	SF268	viability	CACTCTGTTCCTTTGAGGTAGGG	SP1	ENSG00000185591	-0.263280488842125	[]	[]	-2	hSpCas9	negative selection	2883509
53382708	53382731	12	-	27260157	SF268	viability	ATTCAGGGCCACTGGTACATTGG	SP1	ENSG00000185591	-0.550869205612407	[]	[]	-4	hSpCas9	negative selection	2885431
53380287	53380310	12	-	27260157	SF268	viability	CTCATCCTTACCGCTCATGGTGG	SP1	ENSG00000185591	-0.249963863704985	[]	[]	-2	hSpCas9	negative selection	2886393
53382269	53382292	12	+	27260157	SF268	viability	CAGATCATCTCTTCCTCCTCTGG	SP1	ENSG00000185591	-0.428372004957743	[]	[]	-3	hSpCas9	negative selection	2886737
53382418	53382441	12	-	27260157	SF268	viability	GTAGTCCTGTCAGAACTTGCTGG	SP1	ENSG00000185591	-0.741127721898909	[]	[]	-5	hSpCas9	negative selection	2891538
53383015	53383038	12	+	27260157	SF268	viability	CCAGAGGGTCAGTGGGCTACAGG	SP1	ENSG00000185591	0.393983641164054	[]	[]	4	hSpCas9	negative selection	2912050
53381706	53381729	12	+	27260157	SF268	viability	AAAGGAGTTGGTGGCAATAATGG	SP1	ENSG00000185591	-0.4842645034958	[]	[]	-4	hSpCas9	negative selection	2913110
53383281	53383304	12	+	27260157	SF268	viability	ACTCTGGTCCCATCATCATCCGG	SP1	ENSG00000185591	-1.01001733344502	[]	[]	-7	hSpCas9	negative selection	2914178
53381671	53381694	12	-	27260157	SF268	viability	CACAGCTGTCATTTCATCCATGG	SP1	ENSG00000185591	-1.02104939390682	[]	[]	-7	hSpCas9	negative selection	2918565
53381752	53381775	12	-	27260157	SF268	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.259656003237455	[]	[]	-2	hSpCas9	negative selection	2918830
53383189	53383212	12	-	27260157	SF268	viability	CTGACAATGGTGCTGCTTGGAGG	SP1	ENSG00000185591	-0.427602280082901	[]	[]	-3	hSpCas9	negative selection	2925289
53381778	53381801	12	+	27260157	SF268	viability	ACAGGCAGTAGCAGCAGCACTGG	SP1	ENSG00000185591	-0.136945319194852	[]	[]	-1	hSpCas9	negative selection	2925739
53382242	53382265	12	+	27260157	SF268	viability	CAACTTTCACAGGGTGCCAATGG	SP1	ENSG00000185591	0.0978658650104115	[]	[]	0	hSpCas9	negative selection	2928489
53381760	53381783	12	+	27260157	SF268	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	0.105159127587261	[]	[]	0	hSpCas9	negative selection	2948392
53381792	53381815	12	+	27260157	SF268	viability	CAGCACTGGAGGAGGAGGGCAGG	SP1	ENSG00000185591	0.0151164683708061	[]	[]	0	hSpCas9	negative selection	2948822
53380652	53380675	12	-	27260157	SF268	viability	ACCAGGCAGGCGGTTGGCCCGGG	SP1	ENSG00000185591	0.068335764569051	[]	[]	0	hSpCas9	negative selection	2949079
53382476	53382499	12	+	27260157	SF268	viability	CCACAGTTCCAGACCGTTGATGG	SP1	ENSG00000185591	-0.013570078098753	[]	[]	0	hSpCas9	negative selection	2949111
53382475	53382498	12	-	27260157	SF268	viability	CATCAACGGTCTGGAACTGTGGG	SP1	ENSG00000185591	0.192674342694455	[]	[]	0	hSpCas9	negative selection	2952547
53382234	53382257	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-0.0429662434058814	[4,4]	[3,3]	0	hSpCas9	positive selection	3022846
53382361	53382384	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAATCGCACAGTCTCTGGTGGG	SP1	ENSG00000185591	-0.15795082876599162	[3,3]	[2,2]	-2	hSpCas9	positive selection	3022847
53382300	53382323	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTACCTCAAAGGAACAGAGTGG	SP1	ENSG00000185591	-0.07631160179334368	[3,3]	[2,2]	-1	hSpCas9	positive selection	3022848
53383001	53383024	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAAGGCCAGACACCCCAGAGGG	SP1	ENSG00000185591	-0.7698520461277206	[2,2]	[0,0]	-8	hSpCas9	positive selection	3022849
53382234	53382257	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.2170797703021195	[4,4]	[5,2]	4	hSpCas9	positive selection	3090704
53382361	53382384	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAATCGCACAGTCTCTGGTGGG	SP1	ENSG00000185591	0.2460667463081179	[3,3]	[2,2]	4	hSpCas9	positive selection	3090705
53382300	53382323	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTACCTCAAAGGAACAGAGTGG	SP1	ENSG00000185591	-0.8161374218782115	[3,3]	[2,0]	-9	hSpCas9	positive selection	3090706
53383001	53383024	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAAGGCCAGACACCCCAGAGGG	SP1	ENSG00000185591	-0.8442790745331494	[2,2]	[0,0]	-9	hSpCas9	positive selection	3090707
53411157	53411180		+	24336571	A375	resistance to PLX after 7 days	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	0.62439962760043	[12,13]	[17,23]	9	hSpCas9	positive selection	3146777
53411170	53411193		-	24336571	A375	resistance to PLX after 7 days	CATGACGTTGATGCCACTGTTGG	SP1	ENSG00000185591	-0.13085438769290614	[25,28]	[24,24]	-4	hSpCas9	positive selection	3146778
53409506	53409529		+	24336571	A375	resistance to PLX after 7 days	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.3145278462889969	[18,19]	[26,20]	8	hSpCas9	positive selection	3146779
53411157	53411180		+	24336571	A375	resistance to PLX after 14 days	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	2.3172415314555814	[12,15]	[39,27]	9	hSpCas9	positive selection	3204570
53411170	53411193		-	24336571	A375	resistance to PLX after 14 days	CATGACGTTGATGCCACTGTTGG	SP1	ENSG00000185591	-0.5178526719320566	[29,13]	[5,7]	-6	hSpCas9	positive selection	3204571
53409506	53409529		+	24336571	A375	resistance to PLX after 14 days	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.48818113754516906	[18,15]	[5,4]	-6	hSpCas9	positive selection	3204572
53411157	53411180		+	24336571	A375	viability after 7 days	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.17175975025167778	[15]	[12,13]	-2	hSpCas9	negative selection	3262363
53411170	53411193		-	24336571	A375	viability after 7 days	CATGACGTTGATGCCACTGTTGG	SP1	ENSG00000185591	-0.06885609733387588	[29]	[25,28]	-1	hSpCas9	negative selection	3262364
53409506	53409529		+	24336571	A375	viability after 7 days	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.03548709157556729	[19]	[18,19]	0	hSpCas9	negative selection	3262365
53411157	53411180		+	24336571	A375	viability after 14 days	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.09194625145181048	[15]	[12,15]	-1	hSpCas9	negative selection	3320156
53411170	53411193		-	24336571	A375	viability after 14 days	CATGACGTTGATGCCACTGTTGG	SP1	ENSG00000185591	-0.36871377905937663	[29]	[29,13]	-4	hSpCas9	negative selection	3320157
53409506	53409529		+	24336571	A375	viability after 14 days	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.08247572542415826	[19]	[18,15]	-1	hSpCas9	negative selection	3320158
53411105	53411128	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	0.01892147212075612	[150,150]	[0,0]	0	hSpCas9	positive selection	3394389
53381752	53381775	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	2.935398116558473	[19,19]	[0,0]	8	hSpCas9	positive selection	3394390
53381760	53381783	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	2.672363710724679	[23,23]	[0,0]	8	hSpCas9	positive selection	3394391
53382233	53382256	12	+	26780180	HT29	viability (Avana library 4 designs)	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.498766251102992	[]	[]	1	hSpCas9	negative selection	3461454
53382360	53382383	12	+	26780180	HT29	viability (Avana library 4 designs)	AGAATCGCACAGTCTCTGGTGGG	SP1	ENSG00000185591	2.58712498518634	[]	[]	8	hSpCas9	negative selection	3461455
53382299	53382322	12	+	26780180	HT29	viability (Avana library 4 designs)	CCTACCTCAAAGGAACAGAGTGG	SP1	ENSG00000185591	1.97231538648967	[]	[]	7	hSpCas9	negative selection	3461456
53383000	53383023	12	+	26780180	HT29	viability (Avana library 4 designs)	TCAAGGCCAGACACCCCAGAGGG	SP1	ENSG00000185591	0.890603396528354	[]	[]	3	hSpCas9	negative selection	3461457
53382233	53382256	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-5.90116096627394	[]	[]	-6	hSpCas9	negative selection	3562304
53383000	53383023	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAAGGCCAGACACCCCAGAGGG	SP1	ENSG00000185591	-4.42365458019926	[]	[]	-5	hSpCas9	negative selection	3562305
53382299	53382322	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTACCTCAAAGGAACAGAGTGG	SP1	ENSG00000185591	-10.6389044136292	[]	[]	-8	hSpCas9	negative selection	3562306
53382360	53382383	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAATCGCACAGTCTCTGGTGGG	SP1	ENSG00000185591	-3.94210468122329	[]	[]	-4	hSpCas9	negative selection	3562307
53382528	53382551	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAACCATCCTGCTGCACTTGGG	SP1	ENSG00000185591	-1.69081880533461	[]	[]	-2	hSpCas9	negative selection	3562308
53381709	53381732	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGTTGGTGGCAATAATGGGGG	SP1	ENSG00000185591	0.974317871920864	[]	[]	1	hSpCas9	negative selection	3562309
53382233	53382256	12	+	26780180	A375	viability (Avana lentiGuide)	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.560357566234057	[]	[]	0	hSpCas9	negative selection	3670963
53383000	53383023	12	+	26780180	A375	viability (Avana lentiGuide)	TCAAGGCCAGACACCCCAGAGGG	SP1	ENSG00000185591	8.13064607054084	[]	[]	6	hSpCas9	negative selection	3670964
53382299	53382322	12	+	26780180	A375	viability (Avana lentiGuide)	CCTACCTCAAAGGAACAGAGTGG	SP1	ENSG00000185591	5.21199007672277	[]	[]	4	hSpCas9	negative selection	3670965
53382360	53382383	12	+	26780180	A375	viability (Avana lentiGuide)	AGAATCGCACAGTCTCTGGTGGG	SP1	ENSG00000185591	8.43978466568111	[]	[]	6	hSpCas9	negative selection	3670966
53382528	53382551	12	-	26780180	A375	viability (Avana lentiGuide)	AGAACCATCCTGCTGCACTTGGG	SP1	ENSG00000185591	1.87124011768123	[]	[]	2	hSpCas9	negative selection	3670967
53381709	53381732	12	+	26780180	A375	viability (Avana lentiGuide)	GGAGTTGGTGGCAATAATGGGGG	SP1	ENSG00000185591	5.5276168608167	[]	[]	5	hSpCas9	negative selection	3670968
53382233	53382256	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-0.21669379714022194	[6]	[5,4]	-3	hSpCas9	positive selection	3779570
53383000	53383023	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAAGGCCAGACACCCCAGAGGG	SP1	ENSG00000185591	0.1296506870073505	[4]	[4,4]	3	hSpCas9	positive selection	3779571
53382299	53382322	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTACCTCAAAGGAACAGAGTGG	SP1	ENSG00000185591	-0.49898035226001203	[5]	[4,2]	-6	hSpCas9	positive selection	3779572
53382360	53382383	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAATCGCACAGTCTCTGGTGGG	SP1	ENSG00000185591	0.0690811868238263	[6]	[6,6]	1	hSpCas9	positive selection	3779573
53382528	53382551	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAACCATCCTGCTGCACTTGGG	SP1	ENSG00000185591	0.09359642611517986	[5]	[5,5]	2	hSpCas9	positive selection	3779574
53381709	53381732	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGTTGGTGGCAATAATGGGGG	SP1	ENSG00000185591	-0.006730557471038179	[4]	[4,3]	0	hSpCas9	positive selection	3779575
53382233	53382256	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.21951626274778574	[6]	[6,6]	5	hSpCas9	positive selection	3888177
53383000	53383023	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAAGGCCAGACACCCCAGAGGG	SP1	ENSG00000185591	-1.1600723272532636	[4]	[1,0]	-8	hSpCas9	positive selection	3888178
53382299	53382322	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTACCTCAAAGGAACAGAGTGG	SP1	ENSG00000185591	-0.28465715495392635	[5]	[2,4]	-4	hSpCas9	positive selection	3888179
53382360	53382383	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAATCGCACAGTCTCTGGTGGG	SP1	ENSG00000185591	-0.12287882391334724	[5]	[3,5]	-2	hSpCas9	positive selection	3888180
53382528	53382551	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAACCATCCTGCTGCACTTGGG	SP1	ENSG00000185591	0.23115624822704497	[5]	[6,5]	6	hSpCas9	positive selection	3888181
53381709	53381732	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGTTGGTGGCAATAATGGGGG	SP1	ENSG00000185591	0.08513001384217968	[5]	[4,4]	1	hSpCas9	positive selection	3888182
53411105	53411128	12	+	26780180	A375	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	1.56527403622935	[]	[]	8	hSpCas9	negative selection	3998286
53411157	53411180	12	+	26780180	A375	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	1.48747095179398	[]	[]	8	hSpCas9	negative selection	3998287
53381760	53381783	12	+	26780180	A375	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	1.12391522021847	[]	[]	5	hSpCas9	negative selection	3998288
53409493	53409516	12	-	26780180	A375	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	1.78112453664131	[]	[]	9	hSpCas9	negative selection	3998289
53381752	53381775	12	-	26780180	A375	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.871244227751667	[]	[]	3	hSpCas9	negative selection	3998290
53409506	53409529	12	+	26780180	A375	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	1.70177722217931	[]	[]	9	hSpCas9	negative selection	3998291
53411105	53411128	12	+	26780180	HT29	viability (GeCKOv2 library)	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	0.782516327528548	[]	[]	3	hSpCas9	negative selection	4106252
53411157	53411180	12	+	26780180	HT29	viability (GeCKOv2 library)	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	0.429022451648284	[]	[]	1	hSpCas9	negative selection	4106253
53381760	53381783	12	+	26780180	HT29	viability (GeCKOv2 library)	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	1.72438848834453	[]	[]	8	hSpCas9	negative selection	4106254
53409493	53409516	12	-	26780180	HT29	viability (GeCKOv2 library)	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	1.93222086126992	[]	[]	9	hSpCas9	negative selection	4106255
53381752	53381775	12	-	26780180	HT29	viability (GeCKOv2 library)	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	1.12044259309963	[]	[]	5	hSpCas9	negative selection	4106256
53409506	53409529	12	+	26780180	HT29	viability (GeCKOv2 library)	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.746996409266314	[]	[]	3	hSpCas9	negative selection	4106257
53411157	53411180	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	0.4515675406923372	[3]	[2,5]	8	hSpCas9	positive selection	4172905
53411170	53411193	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATGACGTTGATGCCACTGTTGG	SP1	ENSG00000185591	-0.09043214933492683	[4]	[2,2]	-2	hSpCas9	positive selection	4172906
53409506	53409529	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.25337864480760897	[4]	[2,2]	-6	hSpCas9	positive selection	4172907
53411157	53411180	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.5337919920979075	[4]	[0,0,3,0]	-7	hSpCas9	positive selection	4236927
53411170	53411193	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATGACGTTGATGCCACTGTTGG	SP1	ENSG00000185591	1.0809117718570702	[4]	[6,2,4,3]	7	hSpCas9	positive selection	4236928
53409506	53409529	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	1.066656266571599	[4]	[3,2,4,4]	7	hSpCas9	positive selection	4236929
53409506	53409529	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.015866204536484407	[3]	[3,2]	0	hSpCas9	positive selection	4299911
53409493	53409516	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.4605620695218718	[2]	[1,0]	-7	hSpCas9	positive selection	4299912
53411157	53411180	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	0.4710225940556464	[3]	[3,4]	8	hSpCas9	positive selection	4299913
53411105	53411128	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	0.0741946573565599	[3]	[3,1]	1	hSpCas9	positive selection	4364163
53381752	53381775	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.4383835339018024	[1]	[0,0]	-7	hSpCas9	positive selection	4364164
53381760	53381783	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	0.2341911731972705	[1]	[1,1]	5	hSpCas9	positive selection	4364165
53382192	53382214	12	+	27760321	OCIAML3	viability	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-0.8247228639012916	[447,360]	[184,167]	-6	hSpCas9	negative selection	4442268
53382476	53382498	12	-	27760321	OCIAML3	viability	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	-0.4163028653319738	[735,642]	[456,332]	-4	hSpCas9	negative selection	4442269
53382569	53382591	12	-	27760321	OCIAML3	viability	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-0.4247971362146505	[558,534]	[227,437]	-4	hSpCas9	negative selection	4442270
53382870	53382892	12	-	27760321	OCIAML3	viability	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-0.8246400561589369	[454,442]	[176,226]	-6	hSpCas9	negative selection	4442271
53382970	53382992	12	+	27760321	OCIAML3	viability	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	-0.4767946547720814	[249,221]	[121,145]	-5	hSpCas9	negative selection	4442272
53382192	53382214	12	+	27760321	OCIAML2	viability	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-0.3924319319051143	[447,360]	[218,285]	-4	hSpCas9	negative selection	4525731
53382476	53382498	12	-	27760321	OCIAML2	viability	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	0.1304804112698642	[735,642]	[537,702]	1	hSpCas9	negative selection	4525732
53382569	53382591	12	-	27760321	OCIAML2	viability	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-0.4214996898710782	[558,534]	[222,472]	-5	hSpCas9	negative selection	4525733
53382870	53382892	12	-	27760321	OCIAML2	viability	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-0.4261837657290665	[454,442]	[241,308]	-5	hSpCas9	negative selection	4525734
53382970	53382992	12	+	27760321	OCIAML2	viability	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	-0.6300877904578008	[249,221]	[161,71]	-6	hSpCas9	negative selection	4525735
53382192	53382214	12	+	27760321	MV411	viability	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-1.8206104433122394	[447,360]	[13,166]	-8	hSpCas9	negative selection	4609194
53382476	53382498	12	-	27760321	MV411	viability	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	-0.5020077272202926	[735,642]	[35,747]	-3	hSpCas9	negative selection	4609195
53382569	53382591	12	-	27760321	MV411	viability	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-2.40607265453868	[558,534]	[72,60]	-8	hSpCas9	negative selection	4609196
53382870	53382892	12	-	27760321	MV411	viability	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-0.41543206903409846	[454,442]	[37,499]	-3	hSpCas9	negative selection	4609197
53382970	53382992	12	+	27760321	MV411	viability	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	-0.6175685362535657	[249,221]	[32,203]	-4	hSpCas9	negative selection	4609198
53382192	53382214	12	+	27760321	HL60	viability	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-0.4237266583219962	[447,360]	[276,210]	-5	hSpCas9	negative selection	4692657
53382476	53382498	12	-	27760321	HL60	viability	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	0.15120150777581265	[735,642]	[592,656]	1	hSpCas9	negative selection	4692658
53382569	53382591	12	-	27760321	HL60	viability	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-1.2071214380041984	[558,534]	[187,199]	-8	hSpCas9	negative selection	4692659
53382870	53382892	12	-	27760321	HL60	viability	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-1.7338759554935341	[454,442]	[143,74]	-9	hSpCas9	negative selection	4692660
53382970	53382992	12	+	27760321	HL60	viability	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	-1.0264626439568743	[249,221]	[60,129]	-7	hSpCas9	negative selection	4692661
53382192	53382214	12	+	27760321	HT1080	viability	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-1.5663968625331024	[360,281]	[58,25]	-5	hSpCas9	negative selection	4776120
53382476	53382498	12	-	27760321	HT1080	viability	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	1.203452205036827	[642,501]	[392,669]	6	hSpCas9	negative selection	4776121
53382569	53382591	12	-	27760321	HT1080	viability	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-0.10288203898233517	[534,417]	[192,158]	0	hSpCas9	negative selection	4776122
53382870	53382892	12	-	27760321	HT1080	viability	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-0.3868538248305289	[442,345]	[155,80]	-2	hSpCas9	negative selection	4776123
53382970	53382992	12	+	27760321	HT1080	viability	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	1.129092952863131	[221,172]	[162,181]	6	hSpCas9	negative selection	4776124
53382192	53382214	12	+	27760321	HT29	viability after 7 days	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	0.23767477143033786	[360,281]	[468,441,545]	3	hSpCas9	negative selection	4859583
53382476	53382498	12	-	27760321	HT29	viability after 7 days	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	0.5745116034082516	[642,501]	[995,906,1360]	8	hSpCas9	negative selection	4859584
53382569	53382591	12	-	27760321	HT29	viability after 7 days	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-0.8438023454953413	[534,417]	[307,373,336]	-8	hSpCas9	negative selection	4859585
53382870	53382892	12	-	27760321	HT29	viability after 7 days	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-0.41608879185557013	[442,345]	[400,333,406]	-6	hSpCas9	negative selection	4859586
53382970	53382992	12	+	27760321	HT29	viability after 7 days	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	-0.3617048215123867	[221,172]	[286,175,143]	-5	hSpCas9	negative selection	4859587
53382192	53382214	12	+	27760321	HT29	viability after 25 days	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-0.7061676711004479	[360,281]	[131,316,232]	-5	hSpCas9	negative selection	4943046
53382476	53382498	12	-	27760321	HT29	viability after 25 days	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	0.1075842579250148	[642,501]	[558,642,945]	1	hSpCas9	negative selection	4943047
53382569	53382591	12	-	27760321	HT29	viability after 25 days	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-0.9465349973047746	[534,417]	[221,269,367]	-6	hSpCas9	negative selection	4943048
53382870	53382892	12	-	27760321	HT29	viability after 25 days	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-1.3713939868420066	[442,345]	[135,196,193]	-7	hSpCas9	negative selection	4943049
53382970	53382992	12	+	27760321	HT29	viability after 25 days	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	-0.3817909827404845	[221,172]	[171,134,216]	-4	hSpCas9	negative selection	4943050
53382192	53382214	12	+	27760321	HT29	viability after 22 days	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-0.5684105158284747	[360,281]	[146,330,276]	-5	hSpCas9	negative selection	5026509
53382476	53382498	12	-	27760321	HT29	viability after 22 days	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	0.19978678651992743	[642,501]	[569,910,804]	2	hSpCas9	negative selection	5026510
53382569	53382591	12	-	27760321	HT29	viability after 22 days	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-0.9470422871572532	[534,417]	[208,395,253]	-6	hSpCas9	negative selection	5026511
53382870	53382892	12	-	27760321	HT29	viability after 22 days	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-1.098372870107163	[442,345]	[126,232,281]	-7	hSpCas9	negative selection	5026512
53382970	53382992	12	+	27760321	HT29	viability after 22 days	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	0.04203553792738968	[221,172]	[121,370,214]	0	hSpCas9	negative selection	5026513
53382192	53382214	12	+	27760321	HT29	viability after 19 days	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-0.3606858286790087	[360,281]	[365,207,292]	-3	hSpCas9	negative selection	5109972
53382476	53382498	12	-	27760321	HT29	viability after 19 days	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	0.23651834367560964	[642,501]	[1171,528,658]	2	hSpCas9	negative selection	5109973
53382569	53382591	12	-	27760321	HT29	viability after 19 days	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-0.4761862065880724	[534,417]	[233,570,354]	-4	hSpCas9	negative selection	5109974
53382870	53382892	12	-	27760321	HT29	viability after 19 days	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-0.3762248867126864	[442,345]	[284,400,349]	-3	hSpCas9	negative selection	5109975
53382970	53382992	12	+	27760321	HT29	viability after 19 days	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	-0.11277692665315686	[221,172]	[152,241,224]	-1	hSpCas9	negative selection	5109976
53382192	53382214	12	+	27760321	HT29	viability after 16 days	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-0.20431504144943613	[360,281]	[197,457,265]	-2	hSpCas9	negative selection	5193435
53382476	53382498	12	-	27760321	HT29	viability after 16 days	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	0.6227091008325332	[642,501]	[1269,887,829]	7	hSpCas9	negative selection	5193436
53382569	53382591	12	-	27760321	HT29	viability after 16 days	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-1.0641661237366447	[534,417]	[270,346,145]	-7	hSpCas9	negative selection	5193437
53382870	53382892	12	-	27760321	HT29	viability after 16 days	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-0.5585260043775767	[442,345]	[284,171,443]	-5	hSpCas9	negative selection	5193438
53382970	53382992	12	+	27760321	HT29	viability after 16 days	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	-0.06964384578684879	[221,172]	[225,172,234]	0	hSpCas9	negative selection	5193439
53382192	53382214	12	+	27760321	HT29	viability after 13 days	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-0.17843347371504875	[360,281]	[262,380,343]	-2	hSpCas9	negative selection	5276898
53382476	53382498	12	-	27760321	HT29	viability after 13 days	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	0.24058210288917103	[642,501]	[986,726,647]	3	hSpCas9	negative selection	5276899
53382569	53382591	12	-	27760321	HT29	viability after 13 days	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-0.635378436131744	[534,417]	[399,353,315]	-6	hSpCas9	negative selection	5276900
53382870	53382892	12	-	27760321	HT29	viability after 13 days	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-0.5937812016093009	[442,345]	[192,447,270]	-6	hSpCas9	negative selection	5276901
53382970	53382992	12	+	27760321	HT29	viability after 13 days	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	0.47121624337925283	[221,172]	[274,277,394]	6	hSpCas9	negative selection	5276902
53382192	53382214	12	+	27760321	HT29	viability after 10 days	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-0.1109022628484726	[360,281]	[469,244,395]	-1	hSpCas9	negative selection	5360361
53382476	53382498	12	-	27760321	HT29	viability after 10 days	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	0.21313813990188735	[642,501]	[775,857,851]	3	hSpCas9	negative selection	5360362
53382569	53382591	12	-	27760321	HT29	viability after 10 days	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-0.17666661832479078	[534,417]	[498,415,657]	-2	hSpCas9	negative selection	5360363
53382870	53382892	12	-	27760321	HT29	viability after 10 days	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-0.3782539314747161	[442,345]	[167,375,587]	-5	hSpCas9	negative selection	5360364
53382970	53382992	12	+	27760321	HT29	viability after 10 days	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	0.07117923147964134	[221,172]	[311,233,230]	0	hSpCas9	negative selection	5360365
53382192	53382214	12	+	27760321	MOLM13	viability	AGGGCCCGAGTCAGTCAGGGGG	SP1	ENSG00000185591	-1.5940266896196036	[447,360]	[18,122]	-7	hSpCas9	negative selection	5443824
53382476	53382498	12	-	27760321	MOLM13	viability	CATCAACGGTCTGGAACTGTGG	SP1	ENSG00000185591	1.0132966784370718	[735,642]	[1052,553]	7	hSpCas9	negative selection	5443825
53382569	53382591	12	-	27760321	MOLM13	viability	TAATCTGTTGGTTTGCACCTGG	SP1	ENSG00000185591	-1.2831379922218005	[558,534]	[200,63]	-6	hSpCas9	negative selection	5443826
53382870	53382892	12	-	27760321	MOLM13	viability	GCTTGTGATGATACCAAGCTGG	SP1	ENSG00000185591	-2.926489487397216	[454,442]	[54,14]	-9	hSpCas9	negative selection	5443827
53382970	53382992	12	+	27760321	MOLM13	viability	TACTACCAGTGGATCATCAGGG	SP1	ENSG00000185591	-1.6322664905038617	[249,221]	[30,52]	-7	hSpCas9	negative selection	5443828
53380366	53380389	12	+	27661255	K562	viability	GGGCGATCCCCGCCGTGAAGCGG	SP1	ENSG00000185591	-0.3557198855370688	[1065,1076]	[759,590]	-7	dCas9-KRAB	negative selection	5513598
53380210	53380233	12	-	27661255	K562	viability	GAAAAACGCGGACGCTGACGAGG	SP1	ENSG00000185591	-0.9308858480335032	[3403,3318]	[1515,1317]	-8	dCas9-KRAB	negative selection	5513599
53380222	53380245	12	-	27661255	K562	viability	GGGGGGGGCCGGGAAAAACGCGG	SP1	ENSG00000185591	-0.27074471555758994	[737,817]	[619,423]	-6	dCas9-KRAB	negative selection	5513600
53380290	53380313	12	-	27661255	K562	viability	GGACTCATCCTTACCGCTCATGG	SP1	ENSG00000185591	-0.5460212722130251	[264,286]	[173,130]	-8	dCas9-KRAB	negative selection	5513601
53409506	53409529	12	+	27260156	BXPC3	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.07061071196935248	[644]	[678,689,672,800]	1	hSpCas9	negative selection	5572371
53409493	53409516	12	-	27260156	BXPC3	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.11255569800907056	[385]	[329,306,419,452]	-3	hSpCas9	negative selection	5572372
53411157	53411180	12	+	27260156	BXPC3	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.3850156288699496	[645]	[389,536,595,561]	-7	hSpCas9	negative selection	5572373
53411105	53411128	12	+	27260156	BXPC3	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.49434091118386203	[489]	[308,414,302,435]	-8	hSpCas9	negative selection	5636623
53381752	53381775	12	-	27260156	BXPC3	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.24543093926332205	[165]	[83,157,110,249]	-5	hSpCas9	negative selection	5636624
53381760	53381783	12	+	27260156	BXPC3	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.48790990418830127	[148]	[103,94,116,131]	-8	hSpCas9	negative selection	5636625
53409506	53409529	12	+	27260156	A673	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.042793140053904055	[644]	[794,707,783,910]	1	hSpCas9	negative selection	5693622
53409493	53409516	12	-	27260156	A673	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.2952342282269247	[385]	[520,330,306,368]	-6	hSpCas9	negative selection	5693623
53411157	53411180	12	+	27260156	A673	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.28364111384486723	[645]	[670,626,630,621]	-6	hSpCas9	negative selection	5693624
53411105	53411128	12	+	27260156	A673	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.15287501417951	[489]	[429,499,571,606]	-4	hSpCas9	negative selection	5757874
53381752	53381775	12	-	27260156	A673	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.2438827007036306	[165]	[191,172,153,155]	-6	hSpCas9	negative selection	5757875
53381760	53381783	12	+	27260156	A673	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.5800666089947373	[148]	[110,90,139,136]	-8	hSpCas9	negative selection	5757876
53409506	53409529	12	+	27260156	A375	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.052624239346353074	[644]	[880,811,600,632]	0	hSpCas9	negative selection	5814873
53409493	53409516	12	-	27260156	A375	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.25978865544572016	[385]	[322,288,575,311]	-4	hSpCas9	negative selection	5814874
53411157	53411180	12	+	27260156	A375	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.8176915643743607	[645]	[255,635,470,380]	-8	hSpCas9	negative selection	5814875
53411105	53411128	12	+	27260156	A375	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.4058371536336326	[489]	[402,435,403,477]	-5	hSpCas9	negative selection	5879125
53381752	53381775	12	-	27260156	A375	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.9558132061031497	[165]	[125,109,110,58]	-8	hSpCas9	negative selection	5879126
53381760	53381783	12	+	27260156	A375	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.3121314359517917	[148]	[121,210,97,138]	-4	hSpCas9	negative selection	5879127
53409506	53409529	12	+	27260156	COLO741	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.2562558134853387	[644]	[1179,803,982]	5	hSpCas9	negative selection	5936124
53409493	53409516	12	-	27260156	COLO741	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.19541487141888114	[385]	[518,341,436]	-4	hSpCas9	negative selection	5936125
53411157	53411180	12	+	27260156	COLO741	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.23111407496133968	[645]	[623,752,722]	-5	hSpCas9	negative selection	5936126
53411105	53411128	12	+	27260156	COLO741	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.2336630635056239	[489]	[394,436,736]	-5	hSpCas9	negative selection	6000376
53381752	53381775	12	-	27260156	COLO741	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.4772524690067588	[165]	[134,107,207]	-7	hSpCas9	negative selection	6000377
53381760	53381783	12	+	27260156	COLO741	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.5865089591544401	[148]	[178,128,79]	-8	hSpCas9	negative selection	6000378
53409506	53409529	12	+	27260156	CAL120	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.02933337403299008	[644]	[879,808,685]	0	hSpCas9	negative selection	6057375
53409493	53409516	12	-	27260156	CAL120	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.8276207932469501	[385]	[381,310,137]	-8	hSpCas9	negative selection	6057376
53411157	53411180	12	+	27260156	CAL120	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-1.2250899998616298	[645]	[473,229,346]	-9	hSpCas9	negative selection	6057377
53411105	53411128	12	+	27260156	CAL120	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.25425363744404766	[489]	[466,558,500]	-4	hSpCas9	negative selection	6121627
53381752	53381775	12	-	27260156	CAL120	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-1.3309356806205472	[165]	[74,74,94]	-9	hSpCas9	negative selection	6121628
53381760	53381783	12	+	27260156	CAL120	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.17927752084006943	[148]	[122,139,220]	-3	hSpCas9	negative selection	6121629
53409506	53409529	12	+	27260156	CADOES1	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.12548351821507991	[644]	[527,694,612,786]	2	hSpCas9	negative selection	6178626
53409493	53409516	12	-	27260156	CADOES1	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.07672777092509592	[385]	[387,291,325,355]	-1	hSpCas9	negative selection	6178627
53411157	53411180	12	+	27260156	CADOES1	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.43868459623530087	[645]	[461,319,542,447]	-6	hSpCas9	negative selection	6178628
53411105	53411128	12	+	27260156	CADOES1	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.1528340261930096	[489]	[276,413,487,462]	-3	hSpCas9	negative selection	6242878
53381752	53381775	12	-	27260156	CADOES1	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.4277300709415959	[165]	[156,104,81,114]	-6	hSpCas9	negative selection	6242879
53381760	53381783	12	+	27260156	CADOES1	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.5181935455399258	[148]	[44,159,118,61]	-7	hSpCas9	negative selection	6242880
53409506	53409529	12	+	27260156	EWS502	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.20730139061313674	[644]	[673,696,862,947]	3	hSpCas9	negative selection	6299877
53409493	53409516	12	-	27260156	EWS502	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.4128469029937981	[385]	[193,325,440,278]	-6	hSpCas9	negative selection	6299878
53411157	53411180	12	+	27260156	EWS502	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.34678552644703214	[645]	[407,706,480,563]	-5	hSpCas9	negative selection	6299879
53411105	53411128	12	+	27260156	EWS502	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.256120344739232	[489]	[315,318,468,668]	-4	hSpCas9	negative selection	6364129
53381752	53381775	12	-	27260156	EWS502	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.4007088717796372	[165]	[102,129,226,72]	-6	hSpCas9	negative selection	6364130
53381760	53381783	12	+	27260156	EWS502	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.35127904501187013	[148]	[105,117,134,138]	-6	hSpCas9	negative selection	6364131
53409506	53409529	12	+	27260156	EW8	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.10391451661517087	[644]	[621,526,382,444]	-2	hSpCas9	negative selection	6421128
53409493	53409516	12	-	27260156	EW8	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.03364505582523403	[385]	[290,456,173,320]	0	hSpCas9	negative selection	6421129
53411157	53411180	12	+	27260156	EW8	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.39556705051580443	[645]	[290,460,452,364]	-6	hSpCas9	negative selection	6421130
53411105	53411128	12	+	27260156	EW8	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.606528912684483	[489]	[288,266,354,118]	-8	hSpCas9	negative selection	6485380
53381752	53381775	12	-	27260156	EW8	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-1.0812100113544507	[165]	[67,53,78,50]	-9	hSpCas9	negative selection	6485381
53381760	53381783	12	+	27260156	EW8	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.38247394798070466	[148]	[182,62,45,95]	-6	hSpCas9	negative selection	6485382
53409506	53409529	12	+	27260156	CORL105	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.06123949774437526	[644]	[755,675,938,559]	-1	hSpCas9	negative selection	6542379
53409493	53409516	12	-	27260156	CORL105	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.08239217432448909	[385]	[392,357,602,380]	-1	hSpCas9	negative selection	6542380
53411157	53411180	12	+	27260156	CORL105	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.2894584985311995	[645]	[605,553,659,661]	-5	hSpCas9	negative selection	6542381
53411105	53411128	12	+	27260156	CORL105	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.09116879265588193	[489]	[423,552,755,450]	-2	hSpCas9	negative selection	6606631
53381752	53381775	12	-	27260156	CORL105	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.2828268105141323	[165]	[239,124,193,88]	-5	hSpCas9	negative selection	6606632
53381760	53381783	12	+	27260156	CORL105	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.6121665542962123	[148]	[132,93,129,102]	-8	hSpCas9	negative selection	6606633
53409506	53409529	12	+	27260156	HS294T	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.6637469964204511	[644]	[101,142,212,180]	-7	hSpCas9	negative selection	6663630
53409493	53409516	12	-	27260156	HS294T	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.6981641049879393	[385]	[57,61,109,151]	-7	hSpCas9	negative selection	6663631
53411157	53411180	12	+	27260156	HS294T	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.5687961278302025	[645]	[115,111,193,275]	-7	hSpCas9	negative selection	6663632
53411105	53411128	12	+	27260156	HS294T	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	0.3643082245112021	[489]	[288,209,175,306]	5	hSpCas9	negative selection	6727882
53381752	53381775	12	-	27260156	HS294T	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.4864607095306166	[165]	[42,42,53,42]	-6	hSpCas9	negative selection	6727883
53381760	53381783	12	+	27260156	HS294T	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-1.1878200618774333	[148]	[34,12,19,33]	-9	hSpCas9	negative selection	6727884
53409506	53409529	12	+	27260156	HCC44	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.008427726829756954	[644]	[677,707,758,752]	0	hSpCas9	negative selection	6784881
53409493	53409516	12	-	27260156	HCC44	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.6366573105238659	[385]	[342,366,258,145]	-7	hSpCas9	negative selection	6784882
53411157	53411180	12	+	27260156	HCC44	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.700788423494745	[645]	[413,375,444,561]	-7	hSpCas9	negative selection	6784883
53411105	53411128	12	+	27260156	HCC44	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.31671586313217537	[489]	[536,372,429,451]	-5	hSpCas9	negative selection	6849133
53381752	53381775	12	-	27260156	HCC44	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.6518433539593662	[165]	[144,151,60,106]	-7	hSpCas9	negative selection	6849134
53381760	53381783	12	+	27260156	HCC44	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.6140909209839478	[148]	[54,49,98,232]	-7	hSpCas9	negative selection	6849135
53409506	53409529	12	+	27260156	G402	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.06398984614004011	[644]	[761,735,843,670]	-1	hSpCas9	negative selection	6906132
53409493	53409516	12	-	27260156	G402	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.3189068256844716	[385]	[501,521,403,119]	-4	hSpCas9	negative selection	6906133
53411157	53411180	12	+	27260156	G402	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.3497790828200578	[645]	[690,1004,450,369]	-4	hSpCas9	negative selection	6906134
53411105	53411128	12	+	27260156	G402	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.14214257279233522	[489]	[539,454,457,698]	-2	hSpCas9	negative selection	6970384
53381752	53381775	12	-	27260156	G402	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.5514663457769888	[165]	[150,253,83,74]	-6	hSpCas9	negative selection	6970385
53381760	53381783	12	+	27260156	G402	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.13929039561743384	[148]	[215,126,181,140]	-2	hSpCas9	negative selection	6970386
53409506	53409529	12	+	27260156	L33	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.14415865283910573	[644]	[771,254,486,680]	3	hSpCas9	negative selection	7027383
53409493	53409516	12	-	27260156	L33	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.3533477253999694	[385]	[200,93,294,311]	-7	hSpCas9	negative selection	7027384
53411157	53411180	12	+	27260156	L33	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.4128355503729256	[645]	[390,212,407,384]	-7	hSpCas9	negative selection	7027385
53411105	53411128	12	+	27260156	L33	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.12767068588993385	[489]	[408,187,225,565]	-3	hSpCas9	negative selection	7091635
53381752	53381775	12	-	27260156	L33	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.14142982240965174	[165]	[226,65,106,172]	3	hSpCas9	negative selection	7091636
53381760	53381783	12	+	27260156	L33	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.8722026553131328	[148]	[71,26,58,93]	-9	hSpCas9	negative selection	7091637
53409506	53409529	12	+	27260156	K562	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.3287147947949117	[644]	[429,428,534,426]	-4	hSpCas9	negative selection	7148634
53409493	53409516	12	-	27260156	K562	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.516919441689757	[385]	[309,146,199,293]	-6	hSpCas9	negative selection	7148635
53411157	53411180	12	+	27260156	K562	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.7385663352297936	[645]	[340,504,227,310]	-7	hSpCas9	negative selection	7148636
53411105	53411128	12	+	27260156	K562	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.3849324889289918	[489]	[529,169,246,384]	-5	hSpCas9	negative selection	7212886
53381752	53381775	12	-	27260156	K562	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.968863308127212	[165]	[4,74,73,133]	-8	hSpCas9	negative selection	7212887
53381760	53381783	12	+	27260156	K562	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.744401753891414	[148]	[77,136,39,64]	-7	hSpCas9	negative selection	7212888
53409506	53409529	12	+	27260156	HT29	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.3795001215615072	[644]	[641,592,600,575]	-6	hSpCas9	negative selection	7269885
53409493	53409516	12	-	27260156	HT29	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.5517005566559093	[385]	[301,360,312,305]	-7	hSpCas9	negative selection	7269886
53411157	53411180	12	+	27260156	HT29	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.5720979143037154	[645]	[607,568,658,309]	-7	hSpCas9	negative selection	7269887
53411105	53411128	12	+	27260156	HT29	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.19703222594850653	[489]	[602,610,436,446]	-4	hSpCas9	negative selection	7334137
53381752	53381775	12	-	27260156	HT29	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.3277487020669172	[165]	[137,197,151,155]	-6	hSpCas9	negative selection	7334138
53381760	53381783	12	+	27260156	HT29	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.39657018895958984	[148]	[158,169,97,127]	-6	hSpCas9	negative selection	7334139
53409506	53409529	12	+	27260156	MHHES1	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.09348612023118924	[644]	[905,873,740,622]	1	hSpCas9	negative selection	7391136
53409493	53409516	12	-	27260156	MHHES1	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	0.1121169562465133	[385]	[662,350,393,470]	2	hSpCas9	negative selection	7391137
53411157	53411180	12	+	27260156	MHHES1	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.1386691942186628	[645]	[537,814,712,581]	-3	hSpCas9	negative selection	7391138
53411105	53411128	12	+	27260156	MHHES1	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	0.1693122652530727	[489]	[451,786,734,515]	3	hSpCas9	negative selection	7455388
53381752	53381775	12	-	27260156	MHHES1	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.6906980303046284	[165]	[115,223,65,74]	-8	hSpCas9	negative selection	7455389
53381760	53381783	12	+	27260156	MHHES1	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.4076422223031875	[148]	[158,39,139,152]	-6	hSpCas9	negative selection	7455390
53409506	53409529	12	+	27260156	MEWO	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.20380979499662516	[644]	[865,689,561]	4	hSpCas9	negative selection	7512387
53409493	53409516	12	-	27260156	MEWO	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.5426500649507255	[385]	[253,221,268]	-8	hSpCas9	negative selection	7512388
53411157	53411180	12	+	27260156	MEWO	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.4614432651201581	[645]	[334,553,406]	-7	hSpCas9	negative selection	7512389
53411105	53411128	12	+	27260156	MEWO	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.21311427274323735	[489]	[600,424,199]	-5	hSpCas9	negative selection	7576639
53381752	53381775	12	-	27260156	MEWO	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.19541787710579062	[165]	[150,101,156]	-4	hSpCas9	negative selection	7576640
53381760	53381783	12	+	27260156	MEWO	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-1.206434362667495	[148]	[79,60,43]	-9	hSpCas9	negative selection	7576641
53409506	53409529	12	+	27260156	LNCAPCLONEFGC	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.1589818614062914	[644]	[799,538,715,567]	2	hSpCas9	negative selection	7633638
53409493	53409516	12	-	27260156	LNCAPCLONEFGC	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.18554828764943493	[385]	[171,397,345,315]	-3	hSpCas9	negative selection	7633639
53411157	53411180	12	+	27260156	LNCAPCLONEFGC	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.3351665459994961	[645]	[405,416,622,436]	-5	hSpCas9	negative selection	7633640
53411105	53411128	12	+	27260156	LNCAPCLONEFGC	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	0.07374508290097287	[489]	[519,418,470,460]	1	hSpCas9	negative selection	7697890
53381752	53381775	12	-	27260156	LNCAPCLONEFGC	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.4738538118449418	[165]	[53,132,138,110]	-6	hSpCas9	negative selection	7697891
53381760	53381783	12	+	27260156	LNCAPCLONEFGC	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.4732334924469521	[148]	[117,100,68,95]	-6	hSpCas9	negative selection	7697892
53409506	53409529	12	+	27260156	PANC0327	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.46492849780579576	[644]	[515,254,326,590]	-6	hSpCas9	negative selection	7754889
53409493	53409516	12	-	27260156	PANC0327	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.029309473265109187	[385]	[285,459,412,164]	0	hSpCas9	negative selection	7754890
53411157	53411180	12	+	27260156	PANC0327	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.249395562450672	[645]	[537,324,627,464]	-4	hSpCas9	negative selection	7754891
53411105	53411128	12	+	27260156	PANC0327	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	0.1523502409063176	[489]	[591,472,407,471]	2	hSpCas9	negative selection	7819141
53381752	53381775	12	-	27260156	PANC0327	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.5170565453739302	[165]	[65,88,150,104]	-6	hSpCas9	negative selection	7819142
53381760	53381783	12	+	27260156	PANC0327	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.7128210944752085	[148]	[124,77,78,44]	-7	hSpCas9	negative selection	7819143
53409506	53409529	12	+	27260156	NCIH2009	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.971016569638413	[644]	[559,581,253]	-8	hSpCas9	negative selection	7876140
53409493	53409516	12	-	27260156	NCIH2009	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-1.6509144367848876	[385]	[224,195,103]	-9	hSpCas9	negative selection	7876141
53411157	53411180	12	+	27260156	NCIH2009	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-1.0120471918640541	[645]	[572,426,366]	-8	hSpCas9	negative selection	7876142
53411105	53411128	12	+	27260156	NCIH2009	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.7173609475075656	[489]	[552,385,336]	-7	hSpCas9	negative selection	7940392
53381752	53381775	12	-	27260156	NCIH2009	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-2.5891544389715335	[165]	[49,28,38]	-9	hSpCas9	negative selection	7940393
53381760	53381783	12	+	27260156	NCIH2009	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.8578285632874993	[148]	[97,118,123]	-8	hSpCas9	negative selection	7940394
53409506	53409529	12	+	27260156	NCIH1373	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.35432429347520156	[644]	[628,596,512,137]	-4	hSpCas9	negative selection	7997391
53409493	53409516	12	-	27260156	NCIH1373	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-1.0263146295696024	[385]	[199,308,157,43]	-8	hSpCas9	negative selection	7997392
53411157	53411180	12	+	27260156	NCIH1373	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-1.1150925849640718	[645]	[350,512,312,33]	-8	hSpCas9	negative selection	7997393
53411105	53411128	12	+	27260156	NCIH1373	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-1.0718686559823454	[489]	[204,271,289,69]	-8	hSpCas9	negative selection	8061643
53381752	53381775	12	-	27260156	NCIH1373	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.4764380981917984	[165]	[89,259,70,23]	-5	hSpCas9	negative selection	8061644
53381760	53381783	12	+	27260156	NCIH1373	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-1.4282679844255077	[148]	[39,33,86,22]	-8	hSpCas9	negative selection	8061645
53409506	53409529	12	+	27260156	PATU8902	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.38868336130094483	[644]	[1249,870,369,273]	-4	hSpCas9	negative selection	8118642
53409493	53409516	12	-	27260156	PATU8902	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-1.196327533213535	[385]	[226,277,133,335]	-8	hSpCas9	negative selection	8118643
53411157	53411180	12	+	27260156	PATU8902	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.7900497749700887	[645]	[333,499,622,605]	-6	hSpCas9	negative selection	8118644
53411105	53411128	12	+	27260156	PATU8902	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.33307432442777274	[489]	[623,613,390,575]	-3	hSpCas9	negative selection	8182894
53381752	53381775	12	-	27260156	PATU8902	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-2.726347822399048	[165]	[47,7,27,59]	-9	hSpCas9	negative selection	8182895
53381760	53381783	12	+	27260156	PATU8902	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.42232560534610597	[148]	[70,65,280,169]	-4	hSpCas9	negative selection	8182896
53409506	53409529	12	+	27260156	PANC1	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.161203485143592	[644]	[521,746,608,617]	2	hSpCas9	negative selection	8239893
53409493	53409516	12	-	27260156	PANC1	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.31398729751336496	[385]	[264,398,338,112]	-5	hSpCas9	negative selection	8239894
53411157	53411180	12	+	27260156	PANC1	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.19132795795264906	[645]	[260,770,526,446]	-3	hSpCas9	negative selection	8239895
53411105	53411128	12	+	27260156	PANC1	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	0.0636939146608313	[489]	[415,404,545,387]	1	hSpCas9	negative selection	8304145
53381752	53381775	12	-	27260156	PANC1	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.24800292183822803	[165]	[62,180,120,125]	-4	hSpCas9	negative selection	8304146
53381760	53381783	12	+	27260156	PANC1	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.5604594358985651	[148]	[144,79,33,83]	-7	hSpCas9	negative selection	8304147
53409506	53409529	12	+	27260156	PANC0813	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.7187359637280777	[644]	[472,445,412,506]	-7	hSpCas9	negative selection	8361144
53409493	53409516	12	-	27260156	PANC0813	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.7154917950392772	[385]	[273,200,399,231]	-7	hSpCas9	negative selection	8361145
53411157	53411180	12	+	27260156	PANC0813	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.9642793575210327	[645]	[393,332,271,546]	-8	hSpCas9	negative selection	8361146
53411105	53411128	12	+	27260156	PANC0813	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.39195481046954345	[489]	[398,339,557,452]	-6	hSpCas9	negative selection	8425396
53381752	53381775	12	-	27260156	PANC0813	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-1.763396361172365	[165]	[26,68,57,71]	-9	hSpCas9	negative selection	8425397
53381760	53381783	12	+	27260156	PANC0813	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-1.1060986180183736	[148]	[33,81,124,79]	-8	hSpCas9	negative selection	8425398
53409506	53409529	12	+	27260156	RDES	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.07438711238316775	[644]	[654,684,664,817]	-1	hSpCas9	negative selection	8482395
53409493	53409516	12	-	27260156	RDES	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.4204756871507298	[385]	[301,294,315,426]	-6	hSpCas9	negative selection	8482396
53411157	53411180	12	+	27260156	RDES	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.40284944397405603	[645]	[498,537,530,696]	-6	hSpCas9	negative selection	8482397
53411105	53411128	12	+	27260156	RDES	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.606436255139845	[489]	[268,291,550,398]	-8	hSpCas9	negative selection	8546647
53381752	53381775	12	-	27260156	RDES	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-1.1374865466558184	[165]	[60,93,73,125]	-9	hSpCas9	negative selection	8546648
53381760	53381783	12	+	27260156	RDES	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.5512537946208402	[148]	[79,68,142,198]	-7	hSpCas9	negative selection	8546649
53409506	53409529	12	+	27260156	PC3	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.35058044202166144	[644]	[603,740,1265,849]	7	hSpCas9	negative selection	8603646
53409493	53409516	12	-	27260156	PC3	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	0.208714794998058	[385]	[253,464,507,625]	4	hSpCas9	negative selection	8603647
53411157	53411180	12	+	27260156	PC3	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.07158956729806293	[645]	[372,453,977,855]	-2	hSpCas9	negative selection	8603648
53411105	53411128	12	+	27260156	PC3	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.17506135412848206	[489]	[206,370,1004,440]	-4	hSpCas9	negative selection	8667898
53381752	53381775	12	-	27260156	PC3	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.5028989160684585	[165]	[118,210,559,206]	8	hSpCas9	negative selection	8667899
53381760	53381783	12	+	27260156	PC3	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.3401869590264721	[148]	[80,147,114,125]	-6	hSpCas9	negative selection	8667900
53409506	53409529	12	+	27260156	PATU8988T	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.3120629807809828	[644]	[510,410,598,474]	-5	hSpCas9	negative selection	8724897
53409493	53409516	12	-	27260156	PATU8988T	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.6312632054160393	[385]	[194,333,245,192]	-7	hSpCas9	negative selection	8724898
53411157	53411180	12	+	27260156	PATU8988T	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.7741370910778166	[645]	[275,487,330,377]	-8	hSpCas9	negative selection	8724899
53411105	53411128	12	+	27260156	PATU8988T	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.2519456970605172	[489]	[566,285,338,387]	-4	hSpCas9	negative selection	8789149
53381752	53381775	12	-	27260156	PATU8988T	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-1.230627704648711	[165]	[81,86,33,72]	-9	hSpCas9	negative selection	8789150
53381760	53381783	12	+	27260156	PATU8988T	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.17803981435563587	[148]	[175,144,68,120]	-3	hSpCas9	negative selection	8789151
53409506	53409529	12	+	27260156	T47D	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.3079095564726464	[644]	[553,616,567,690]	-6	hSpCas9	negative selection	8846148
53409493	53409516	12	-	27260156	T47D	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.552214421160259	[385]	[290,331,243,359]	-8	hSpCas9	negative selection	8846149
53411157	53411180	12	+	27260156	T47D	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.9110817568665361	[645]	[367,370,424,439]	-9	hSpCas9	negative selection	8846150
53411105	53411128	12	+	27260156	T47D	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.5038373525262663	[489]	[402,360,488,357]	-8	hSpCas9	negative selection	8910400
53381752	53381775	12	-	27260156	T47D	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.5294327109527779	[165]	[133,143,126,129]	-8	hSpCas9	negative selection	8910401
53381760	53381783	12	+	27260156	T47D	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.6834900074958736	[148]	[88,107,104,130]	-8	hSpCas9	negative selection	8910402
53409506	53409529	12	+	27260156	SU8686	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.9161139630608888	[644]	[309,440,296,284]	-8	hSpCas9	negative selection	8967399
53409493	53409516	12	-	27260156	SU8686	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-1.140425671694448	[385]	[199,88,233,180]	-8	hSpCas9	negative selection	8967400
53411157	53411180	12	+	27260156	SU8686	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.8651586361781658	[645]	[400,306,329,367]	-8	hSpCas9	negative selection	8967401
53411105	53411128	12	+	27260156	SU8686	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.357463178275764	[489]	[306,382,365,481]	-5	hSpCas9	negative selection	9031651
53381752	53381775	12	-	27260156	SU8686	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.7918035239028303	[165]	[88,100,65,127]	-8	hSpCas9	negative selection	9031652
53381760	53381783	12	+	27260156	SU8686	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.7927157791020871	[148]	[183,44,33,66]	-8	hSpCas9	negative selection	9031653
53409506	53409529	12	+	27260156	SKES1	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.06523776109275392	[644]	[696,728,535,527]	-1	hSpCas9	negative selection	9088650
53409493	53409516	12	-	27260156	SKES1	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.11158292775048195	[385]	[507,406,249,292]	-2	hSpCas9	negative selection	9088651
53411157	53411180	12	+	27260156	SKES1	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.07472101791327818	[645]	[933,463,543,535]	-2	hSpCas9	negative selection	9088652
53411105	53411128	12	+	27260156	SKES1	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.46693169369255594	[489]	[331,430,375,285]	-8	hSpCas9	negative selection	9152902
53381752	53381775	12	-	27260156	SKES1	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.05587709622712511	[165]	[254,152,109,177]	1	hSpCas9	negative selection	9152903
53381760	53381783	12	+	27260156	SKES1	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.39764639588697515	[148]	[89,172,144,52]	-7	hSpCas9	negative selection	9152904
53409506	53409529	12	+	27260156	TOV112D	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.20758175876307478	[644]	[913,855,548,705]	4	hSpCas9	negative selection	9209901
53409493	53409516	12	-	27260156	TOV112D	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.19046718253068945	[385]	[494,427,247,221]	-4	hSpCas9	negative selection	9209902
53411157	53411180	12	+	27260156	TOV112D	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.2731044337781611	[645]	[653,772,491,296]	-5	hSpCas9	negative selection	9209903
53411105	53411128	12	+	27260156	TOV112D	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	0.11189403137430301	[489]	[541,710,421,491]	2	hSpCas9	negative selection	9274153
53381752	53381775	12	-	27260156	TOV112D	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.2659265124952397	[165]	[91,185,118,162]	-5	hSpCas9	negative selection	9274154
53381760	53381783	12	+	27260156	TOV112D	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.6365267820763965	[148]	[90,239,33,54]	-8	hSpCas9	negative selection	9274155
53409506	53409529	12	+	27260156	TC71	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	0.21117879834934344	[644]	[838,756,659,958]	5	hSpCas9	negative selection	9331152
53409493	53409516	12	-	27260156	TC71	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.29495419691176805	[385]	[309,383,360,290]	-7	hSpCas9	negative selection	9331153
53411157	53411180	12	+	27260156	TC71	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.28525429522610624	[645]	[513,473,517,782]	-6	hSpCas9	negative selection	9331154
53411105	53411128	12	+	27260156	TC71	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	-0.11513631714627687	[489]	[475,603,462,391]	-3	hSpCas9	negative selection	9395404
53381752	53381775	12	-	27260156	TC71	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.1961266942305655	[165]	[198,136,170,109]	-5	hSpCas9	negative selection	9395405
53381760	53381783	12	+	27260156	TC71	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.6952340758809954	[148]	[122,94,84,90]	-9	hSpCas9	negative selection	9395406
53409506	53409529	12	+	27260156	TC32	viability	TGGGAAACGCTTCACACGTTCGG	SP1	ENSG00000185591	-0.06277958887702695	[644]	[552,431,835,568]	-1	hSpCas9	negative selection	9452403
53409493	53409516	12	-	27260156	TC32	viability	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.24899845302617718	[385]	[410,134,375,346]	-4	hSpCas9	negative selection	9452404
53411157	53411180	12	+	27260156	TC32	viability	ATTGCCCGTCTTGCCAACAGTGG	SP1	ENSG00000185591	-0.6120583188682363	[645]	[312,292,581,463]	-8	hSpCas9	negative selection	9452405
53411105	53411128	12	+	27260156	TC32	viability	AGCCCTTATTACCACCAATATGG	SP1	ENSG00000185591	0.01526577598423192	[489]	[445,442,502,455]	0	hSpCas9	negative selection	9516655
53381752	53381775	12	-	27260156	TC32	viability	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.9650907691383912	[165]	[92,44,77,111]	-9	hSpCas9	negative selection	9516656
53381760	53381783	12	+	27260156	TC32	viability	CAGGCTCGAAGTAGCAGCACAGG	SP1	ENSG00000185591	-0.41575773312491426	[148]	[125,76,91,124]	-7	hSpCas9	negative selection	9516657
53381752	53381775	12	-	27869803	HPAFII	viability after 27 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-1.7751223152739577	[173]	[23,28,NaN]	-8	hSpCas9	negative selection	9547388
53382233	53382256	12	+	27869803	HPAFII	viability after 27 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-1.0237042605912685	[269]	[5,122,NaN]	-6	hSpCas9	negative selection	9547389
53383150	53383173	12	+	27869803	HPAFII	viability after 27 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-1.3331453129746558	[385]	[73,85,NaN]	-7	hSpCas9	negative selection	9547390
53406632	53406655	12	+	27869803	HPAFII	viability after 27 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-1.5358642267682172	[179]	[54,13,NaN]	-7	hSpCas9	negative selection	9547391
53409493	53409516	12	-	27869803	HPAFII	viability after 27 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-3.7322782541012502	[238]	[9,8,NaN]	-9	hSpCas9	negative selection	9547392
53411177	53411200	12	+	27869803	HPAFII	viability after 27 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.9972865162443695	[300]	[147,21,NaN]	-6	hSpCas9	negative selection	9547393
53381752	53381775	12	-	27869803	HPAFII	viability after 15 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.11893500165349247	[173]	[223,139,NaN]	-1	hSpCas9	negative selection	9629837
53382233	53382256	12	+	27869803	HPAFII	viability after 15 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-0.8308112594944962	[269]	[246,110,NaN]	-7	hSpCas9	negative selection	9629838
53383150	53383173	12	+	27869803	HPAFII	viability after 15 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-0.5202625780254936	[385]	[279,294,NaN]	-5	hSpCas9	negative selection	9629839
53406632	53406655	12	+	27869803	HPAFII	viability after 15 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-0.9819500801976908	[179]	[203,31,NaN]	-7	hSpCas9	negative selection	9629840
53409493	53409516	12	-	27869803	HPAFII	viability after 15 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-1.4330013651692977	[238]	[67,111,NaN]	-8	hSpCas9	negative selection	9629841
53411177	53411200	12	+	27869803	HPAFII	viability after 15 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.6877474913248136	[300]	[362,99,NaN]	-6	hSpCas9	negative selection	9629842
53381752	53381775	12	-	27869803	ASPC1	viability after 36 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-0.5106782803707278	[514]	[132,90,147]	-5	hSpCas9	negative selection	9712286
53382233	53382256	12	+	27869803	ASPC1	viability after 36 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-0.4227123125962381	[624]	[304,118,95]	-4	hSpCas9	negative selection	9712287
53383150	53383173	12	+	27869803	ASPC1	viability after 36 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	0.08217292526474551	[1026]	[767,153,281]	0	hSpCas9	negative selection	9712288
53406632	53406655	12	+	27869803	ASPC1	viability after 36 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-0.1381823063996771	[403]	[56,123,179]	-1	hSpCas9	negative selection	9712289
53409493	53409516	12	-	27869803	ASPC1	viability after 36 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.2019724917090673	[649]	[154,191,228]	-2	hSpCas9	negative selection	9712290
53411177	53411200	12	+	27869803	ASPC1	viability after 36 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	1.048692296416704	[677]	[413,692,375]	8	hSpCas9	negative selection	9712291
53381752	53381775	12	-	27869803	PATU8988S	viability after 35 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.0859274081732565	[344]	[136,157,NaN]	1	hSpCas9	negative selection	9794735
53382233	53382256	12	+	27869803	PATU8988S	viability after 35 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.5807430634305831	[613]	[522,215,NaN]	6	hSpCas9	negative selection	9794736
53383150	53383173	12	+	27869803	PATU8988S	viability after 35 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-0.7302361640403708	[1131]	[198,350,NaN]	-6	hSpCas9	negative selection	9794737
53406632	53406655	12	+	27869803	PATU8988S	viability after 35 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	0.5043832150522491	[382]	[135,301,NaN]	5	hSpCas9	negative selection	9794738
53409493	53409516	12	-	27869803	PATU8988S	viability after 35 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-0.06960831273117374	[502]	[210,174,NaN]	0	hSpCas9	negative selection	9794739
53411177	53411200	12	+	27869803	PATU8988S	viability after 35 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.7200067467034528	[672]	[187,140,NaN]	-6	hSpCas9	negative selection	9794740
53381752	53381775	12	-	27869803	PATU8988S	viability after 31 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	0.21863774341886105	[344]	[145,177,NaN]	2	hSpCas9	negative selection	9877184
53382233	53382256	12	+	27869803	PATU8988S	viability after 31 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	0.7641592058567351	[613]	[472,342,NaN]	8	hSpCas9	negative selection	9877185
53383150	53383173	12	+	27869803	PATU8988S	viability after 31 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-1.3450881783009527	[1131]	[156,203,NaN]	-8	hSpCas9	negative selection	9877186
53406632	53406655	12	+	27869803	PATU8988S	viability after 31 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	0.2831056973107601	[382]	[136,247,NaN]	3	hSpCas9	negative selection	9877187
53409493	53409516	12	-	27869803	PATU8988S	viability after 31 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	0.012287057318432146	[502]	[218,180,NaN]	0	hSpCas9	negative selection	9877188
53411177	53411200	12	+	27869803	PATU8988S	viability after 31 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.6206966982200682	[672]	[203,136,NaN]	-6	hSpCas9	negative selection	9877189
53381752	53381775	12	-	27869803	HPAFII	viability after 35 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-2.599927466257329	[173]	[14,13,NaN]	-8	hSpCas9	negative selection	9959633
53382233	53382256	12	+	27869803	HPAFII	viability after 35 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-1.6573655966593979	[269]	[0,90,NaN]	-7	hSpCas9	negative selection	9959634
53383150	53383173	12	+	27869803	HPAFII	viability after 35 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-1.5865976977746867	[385]	[73,54,NaN]	-7	hSpCas9	negative selection	9959635
53406632	53406655	12	+	27869803	HPAFII	viability after 35 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-1.8489019282525851	[179]	[29,19,NaN]	-7	hSpCas9	negative selection	9959636
53409493	53409516	12	-	27869803	HPAFII	viability after 35 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-3.675961889054841	[238]	[0,18,NaN]	-9	hSpCas9	negative selection	9959637
53411177	53411200	12	+	27869803	HPAFII	viability after 35 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.5278128534766218	[300]	[195,3,NaN]	-3	hSpCas9	negative selection	9959638
53381752	53381775	12	-	27869803	HPAFII	viability after 31 days	GCTACTTCGAGCCTGTGAAAAGG	SP1	ENSG00000185591	-1.2593276438620897	[173]	[24,57,NaN]	-6	hSpCas9	negative selection	10042082
53382233	53382256	12	+	27869803	HPAFII	viability after 31 days	ACAGCCACACAACTTTCACAGGG	SP1	ENSG00000185591	-1.4390367593683056	[269]	[30,82,NaN]	-7	hSpCas9	negative selection	10042083
53383150	53383173	12	+	27869803	HPAFII	viability after 31 days	CCAGCCTCAGCTAGTTCAAGGGG	SP1	ENSG00000185591	-1.4387043160615973	[385]	[77,81,NaN]	-7	hSpCas9	negative selection	10042084
53406632	53406655	12	+	27869803	HPAFII	viability after 31 days	ATACATGATGACACAGCAGGTGG	SP1	ENSG00000185591	-1.4476366398987952	[179]	[48,23,NaN]	-7	hSpCas9	negative selection	10042085
53409493	53409516	12	-	27869803	HPAFII	viability after 31 days	GCGTTTCCCACAGTATGACCAGG	SP1	ENSG00000185591	-3.3958787253301526	[238]	[6,18,NaN]	-9	hSpCas9	negative selection	10042086
53411177	53411200	12	+	27869803	HPAFII	viability after 31 days	TGGCATCAACGTCATGCAGGTGG	SP1	ENSG00000185591	-0.8792650651292077	[300]	[143,34,NaN]	-5	hSpCas9	negative selection	10042087
53406690	53406713	12	+	28162770	P31FUJ	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	0.04021628999203708	[47]	[57]	0	hSpCas9	negative selection	10240885
53383180	53383203	12	-	28162770	P31FUJ	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-1.130922590395165	[245]	[131]	-7	hSpCas9	negative selection	10240886
53382173	53382196	12	+	28162770	P31FUJ	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-1.6779417354826414	[225]	[82]	-8	hSpCas9	negative selection	10240887
53382359	53382382	12	+	28162770	P31FUJ	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-0.5514846397980869	[443]	[355]	-5	hSpCas9	negative selection	10240888
53383296	53383319	12	+	28162770	P31FUJ	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-1.975181294766949	[444]	[132]	-8	hSpCas9	negative selection	10240889
53381781	53381804	12	+	28162770	P31FUJ	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-5.554730299301741	[119]	[2]	-9	hSpCas9	negative selection	10240890
53382590	53382613	12	+	28162770	P31FUJ	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.2533026565134171	[566]	[558]	-2	hSpCas9	negative selection	10240891
53382935	53382958	12	+	28162770	P31FUJ	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.13139168324302708	[768]	[824]	-1	hSpCas9	negative selection	10240892
53382999	53383022	12	+	28162770	P31FUJ	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.7653705798811329	[702]	[485]	-5	hSpCas9	negative selection	10240893
53383058	53383081	12	+	28162770	P31FUJ	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-1.1680965150265632	[108]	[56]	-7	hSpCas9	negative selection	10240894
53406690	53406713	12	+	28162770	TF1	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10410251
53383180	53383203	12	-	28162770	TF1	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	NaN	[NaN]	[90]	1	hSpCas9	negative selection	10410252
53382173	53382196	12	+	28162770	TF1	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	NaN	[NaN]	[210]	1	hSpCas9	negative selection	10410253
53382359	53382382	12	+	28162770	TF1	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	NaN	[NaN]	[600]	1	hSpCas9	negative selection	10410254
53383296	53383319	12	+	28162770	TF1	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	NaN	[NaN]	[1381]	1	hSpCas9	negative selection	10410255
53381781	53381804	12	+	28162770	TF1	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	NaN	[NaN]	[28]	1	hSpCas9	negative selection	10410256
53382590	53382613	12	+	28162770	TF1	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	NaN	[NaN]	[1117]	1	hSpCas9	negative selection	10410257
53382935	53382958	12	+	28162770	TF1	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	NaN	[NaN]	[1514]	1	hSpCas9	negative selection	10410258
53382999	53383022	12	+	28162770	TF1	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	NaN	[NaN]	[791]	1	hSpCas9	negative selection	10410259
53383058	53383081	12	+	28162770	TF1	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10410260
53406690	53406713	12	+	28162770	SKM1	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	-3.3245020385511888	[16]	[2]	-9	hSpCas9	negative selection	10579617
53383180	53383203	12	-	28162770	SKM1	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-1.6919411574576326	[52]	[28]	-8	hSpCas9	negative selection	10579618
53382173	53382196	12	+	28162770	SKM1	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-1.242844818982055	[82]	[61]	-7	hSpCas9	negative selection	10579619
53382359	53382382	12	+	28162770	SKM1	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-0.21019758508220798	[141]	[216]	-2	hSpCas9	negative selection	10579620
53383296	53383319	12	+	28162770	SKM1	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-1.8817079441462734	[147]	[70]	-8	hSpCas9	negative selection	10579621
53381781	53381804	12	+	28162770	SKM1	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-3.5224414161630975	[38]	[5]	-9	hSpCas9	negative selection	10579622
53382590	53382613	12	+	28162770	SKM1	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.7564133563944286	[128]	[134]	-5	hSpCas9	negative selection	10579623
53382935	53382958	12	+	28162770	SKM1	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.4654366014626259	[213]	[273]	-4	hSpCas9	negative selection	10579624
53382999	53383022	12	+	28162770	SKM1	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.5306619229680659	[142]	[174]	-4	hSpCas9	negative selection	10579625
53383058	53383081	12	+	28162770	SKM1	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-1.023635559191656	[22]	[19]	-6	hSpCas9	negative selection	10579626
53406690	53406713	12	+	28162770	SKM1	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	-3.3245020385511888	[16]	[2]	-9	hSpCas9	negative selection	10748983
53383180	53383203	12	-	28162770	SKM1	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-1.6919411574576326	[52]	[28]	-8	hSpCas9	negative selection	10748984
53382173	53382196	12	+	28162770	SKM1	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-1.242844818982055	[82]	[61]	-7	hSpCas9	negative selection	10748985
53382359	53382382	12	+	28162770	SKM1	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-0.21019758508220798	[141]	[216]	-2	hSpCas9	negative selection	10748986
53383296	53383319	12	+	28162770	SKM1	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-1.8817079441462734	[147]	[70]	-8	hSpCas9	negative selection	10748987
53381781	53381804	12	+	28162770	SKM1	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-3.5224414161630975	[38]	[5]	-9	hSpCas9	negative selection	10748988
53382590	53382613	12	+	28162770	SKM1	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.7564133563944286	[128]	[134]	-5	hSpCas9	negative selection	10748989
53382935	53382958	12	+	28162770	SKM1	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.4654366014626259	[213]	[273]	-4	hSpCas9	negative selection	10748990
53382999	53383022	12	+	28162770	SKM1	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.5306619229680659	[142]	[174]	-4	hSpCas9	negative selection	10748991
53383058	53383081	12	+	28162770	SKM1	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-1.023635559191656	[22]	[19]	-6	hSpCas9	negative selection	10748992
53406690	53406713	12	+	28162770	PL21	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	-4.291713481840355	[44]	[0]	-9	hSpCas9	negative selection	10918349
53383180	53383203	12	-	28162770	PL21	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-1.384822886231836	[155]	[25]	-7	hSpCas9	negative selection	10918350
53382173	53382196	12	+	28162770	PL21	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-2.7131487523173488	[225]	[14]	-9	hSpCas9	negative selection	10918351
53382359	53382382	12	+	28162770	PL21	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-1.0852626043729283	[467]	[95]	-6	hSpCas9	negative selection	10918352
53383296	53383319	12	+	28162770	PL21	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-2.79986038551068	[559]	[34]	-9	hSpCas9	negative selection	10918353
53381781	53381804	12	+	28162770	PL21	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-3.6072153075682842	[111]	[3]	-9	hSpCas9	negative selection	10918354
53382590	53382613	12	+	28162770	PL21	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-1.8306226392813667	[473]	[57]	-8	hSpCas9	negative selection	10918355
53382935	53382958	12	+	28162770	PL21	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.47242931494593066	[627]	[196]	-3	hSpCas9	negative selection	10918356
53382999	53383022	12	+	28162770	PL21	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	0.023261852405240813	[467]	[206]	0	hSpCas9	negative selection	10918357
53383058	53383081	12	+	28162770	PL21	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-1.9083848422888487	[68]	[7]	-8	hSpCas9	negative selection	10918358
53406690	53406713	12	+	28162770	P31FUJ	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	0.04021628999203708	[47]	[57]	0	hSpCas9	negative selection	11087715
53383180	53383203	12	-	28162770	P31FUJ	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-1.130922590395165	[245]	[131]	-7	hSpCas9	negative selection	11087716
53382173	53382196	12	+	28162770	P31FUJ	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-1.6779417354826414	[225]	[82]	-8	hSpCas9	negative selection	11087717
53382359	53382382	12	+	28162770	P31FUJ	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-0.5514846397980869	[443]	[355]	-5	hSpCas9	negative selection	11087718
53383296	53383319	12	+	28162770	P31FUJ	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-1.975181294766949	[444]	[132]	-8	hSpCas9	negative selection	11087719
53381781	53381804	12	+	28162770	P31FUJ	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-5.554730299301741	[119]	[2]	-9	hSpCas9	negative selection	11087720
53382590	53382613	12	+	28162770	P31FUJ	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.2533026565134171	[566]	[558]	-2	hSpCas9	negative selection	11087721
53382935	53382958	12	+	28162770	P31FUJ	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.13139168324302708	[768]	[824]	-1	hSpCas9	negative selection	11087722
53382999	53383022	12	+	28162770	P31FUJ	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.7653705798811329	[702]	[485]	-5	hSpCas9	negative selection	11087723
53383058	53383081	12	+	28162770	P31FUJ	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-1.1680965150265632	[108]	[56]	-7	hSpCas9	negative selection	11087724
53406690	53406713	12	+	28162770	OCIAML5	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	-0.9699030611578554	[50]	[46]	-6	hSpCas9	negative selection	11257081
53383180	53383203	12	-	28162770	OCIAML5	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-0.9754489863692789	[121]	[111]	-6	hSpCas9	negative selection	11257082
53382173	53382196	12	+	28162770	OCIAML5	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-1.5365647451360678	[134]	[83]	-7	hSpCas9	negative selection	11257083
53382359	53382382	12	+	28162770	OCIAML5	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-1.2454740541712983	[330]	[251]	-6	hSpCas9	negative selection	11257084
53383296	53383319	12	+	28162770	OCIAML5	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-1.0724566392892971	[239]	[205]	-6	hSpCas9	negative selection	11257085
53381781	53381804	12	+	28162770	OCIAML5	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-6.495922760638722	[49]	[0]	-9	hSpCas9	negative selection	11257086
53382590	53382613	12	+	28162770	OCIAML5	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.39191052587912134	[361]	[497]	-3	hSpCas9	negative selection	11257087
53382935	53382958	12	+	28162770	OCIAML5	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.571375508962882	[581]	[706]	-4	hSpCas9	negative selection	11257088
53382999	53383022	12	+	28162770	OCIAML5	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.09085343045111349	[235]	[399]	0	hSpCas9	negative selection	11257089
53383058	53383081	12	+	28162770	OCIAML5	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	1.5402508519147633	[19]	[104]	9	hSpCas9	negative selection	11257090
53406690	53406713	12	+	28162770	EOL1	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	-3.3608544472917137	[77]	[3]	-9	hSpCas9	negative selection	11426447
53383180	53383203	12	-	28162770	EOL1	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	0.09983168885149313	[208]	[117]	0	hSpCas9	negative selection	11426448
53382173	53382196	12	+	28162770	EOL1	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-4.033223993040168	[403]	[12]	-9	hSpCas9	negative selection	11426449
53382359	53382382	12	+	28162770	EOL1	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-0.6828897619064405	[840]	[275]	-5	hSpCas9	negative selection	11426450
53383296	53383319	12	+	28162770	EOL1	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-2.515796092896079	[900]	[82]	-8	hSpCas9	negative selection	11426451
53381781	53381804	12	+	28162770	EOL1	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-4.726503919608394	[200]	[3]	-9	hSpCas9	negative selection	11426452
53382590	53382613	12	+	28162770	EOL1	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.09548998166601053	[579]	[285]	0	hSpCas9	negative selection	11426453
53382935	53382958	12	+	28162770	EOL1	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.14888767503247546	[805]	[382]	-1	hSpCas9	negative selection	11426454
53382999	53383022	12	+	28162770	EOL1	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.5879727164819823	[601]	[210]	-4	hSpCas9	negative selection	11426455
53383058	53383081	12	+	28162770	EOL1	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-2.204735245374432	[104]	[11]	-8	hSpCas9	negative selection	11426456
53406690	53406713	12	+	28162770	MOLM13	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	-5.43900121406394	[59]	[0]	-9	hSpCas9	negative selection	11595813
53383180	53383203	12	-	28162770	MOLM13	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-1.1585497551527364	[246]	[79]	-6	hSpCas9	negative selection	11595814
53382173	53382196	12	+	28162770	MOLM13	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-1.734739784970439	[289]	[62]	-7	hSpCas9	negative selection	11595815
53382359	53382382	12	+	28162770	MOLM13	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-2.029733453596826	[688]	[121]	-7	hSpCas9	negative selection	11595816
53383296	53383319	12	+	28162770	MOLM13	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-1.7712679222712744	[778]	[164]	-7	hSpCas9	negative selection	11595817
53381781	53381804	12	+	28162770	MOLM13	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-6.94996313334132	[170]	[0]	-9	hSpCas9	negative selection	11595818
53382590	53382613	12	+	28162770	MOLM13	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-1.5660579503787588	[687]	[167]	-6	hSpCas9	negative selection	11595819
53382935	53382958	12	+	28162770	MOLM13	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-1.277263397371395	[1236]	[368]	-6	hSpCas9	negative selection	11595820
53382999	53383022	12	+	28162770	MOLM13	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	0.6061393199222987	[526]	[579]	4	hSpCas9	negative selection	11595821
53383058	53383081	12	+	28162770	MOLM13	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-1.5470609599213927	[96]	[23]	-6	hSpCas9	negative selection	11595822
53406690	53406713	12	+	28162770	HEL	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	0.008866730798254618	[44]	[28]	0	hSpCas9	negative selection	11765179
53383180	53383203	12	-	28162770	HEL	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-0.7474952762779141	[172]	[65]	-5	hSpCas9	negative selection	11765180
53382173	53382196	12	+	28162770	HEL	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-1.8763357330643422	[320]	[55]	-7	hSpCas9	negative selection	11765181
53382359	53382382	12	+	28162770	HEL	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-1.0210790894320385	[563]	[177]	-6	hSpCas9	negative selection	11765182
53383296	53383319	12	+	28162770	HEL	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-1.3451206051274311	[709]	[178]	-7	hSpCas9	negative selection	11765183
53381781	53381804	12	+	28162770	HEL	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-4.3751830759969055	[161]	[4]	-9	hSpCas9	negative selection	11765184
53382590	53382613	12	+	28162770	HEL	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.6020333674407085	[627]	[264]	-4	hSpCas9	negative selection	11765185
53382935	53382958	12	+	28162770	HEL	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.46688565917414127	[860]	[398]	-3	hSpCas9	negative selection	11765186
53382999	53383022	12	+	28162770	HEL	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.18061656875096244	[475]	[268]	-1	hSpCas9	negative selection	11765187
53383058	53383081	12	+	28162770	HEL	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-1.0734682019990518	[91]	[27]	-6	hSpCas9	negative selection	11765188
53406690	53406713	12	+	28162770	MV411	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	-4.659453044825743	[29]	[0]	-9	hSpCas9	negative selection	11934545
53383180	53383203	12	-	28162770	MV411	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-0.4031132915659577	[134]	[85]	-3	hSpCas9	negative selection	11934546
53382173	53382196	12	+	28162770	MV411	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-1.8245122910962395	[184]	[43]	-8	hSpCas9	negative selection	11934547
53382359	53382382	12	+	28162770	MV411	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-0.45254913075830294	[397]	[244]	-3	hSpCas9	negative selection	11934548
53383296	53383319	12	+	28162770	MV411	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-1.9873919737918952	[465]	[98]	-8	hSpCas9	negative selection	11934549
53381781	53381804	12	+	28162770	MV411	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-4.7183467338793115	[124]	[3]	-9	hSpCas9	negative selection	11934550
53382590	53382613	12	+	28162770	MV411	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.8775492260557547	[481]	[220]	-6	hSpCas9	negative selection	11934551
53382935	53382958	12	+	28162770	MV411	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-1.0422951764418062	[708]	[289]	-6	hSpCas9	negative selection	11934552
53382999	53383022	12	+	28162770	MV411	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.5453298350517826	[368]	[212]	-4	hSpCas9	negative selection	11934553
53383058	53383081	12	+	28162770	MV411	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-3.0420690664122096	[87]	[8]	-9	hSpCas9	negative selection	11934554
53406690	53406713	12	+	28162770	MONOMAC1	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	-0.036572174866307705	[16]	[18]	0	hSpCas9	negative selection	12103911
53383180	53383203	12	-	28162770	MONOMAC1	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-0.9295565361945678	[107]	[64]	-6	hSpCas9	negative selection	12103912
53382173	53382196	12	+	28162770	MONOMAC1	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-1.9664239189181374	[149]	[43]	-8	hSpCas9	negative selection	12103913
53382359	53382382	12	+	28162770	MONOMAC1	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-0.7355637747904255	[320]	[220]	-6	hSpCas9	negative selection	12103914
53383296	53383319	12	+	28162770	MONOMAC1	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-1.032650029158671	[347]	[194]	-7	hSpCas9	negative selection	12103915
53381781	53381804	12	+	28162770	MONOMAC1	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-0.2736581286624662	[57]	[54]	-2	hSpCas9	negative selection	12103916
53382590	53382613	12	+	28162770	MONOMAC1	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.33859099127357317	[320]	[290]	-3	hSpCas9	negative selection	12103917
53382935	53382958	12	+	28162770	MONOMAC1	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.6301548009637539	[454]	[336]	-5	hSpCas9	negative selection	12103918
53382999	53383022	12	+	28162770	MONOMAC1	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.2655165849423202	[301]	[287]	-2	hSpCas9	negative selection	12103919
53383058	53383081	12	+	28162770	MONOMAC1	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-0.8100137239503065	[51]	[33]	-6	hSpCas9	negative selection	12103920
53406690	53406713	12	+	28162770	OCIAML2	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	0.4679696300936955	[5]	[45]	4	hSpCas9	negative selection	12273277
53383180	53383203	12	-	28162770	OCIAML2	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	-1.1487017303547988	[21]	[54]	-6	hSpCas9	negative selection	12273278
53382173	53382196	12	+	28162770	OCIAML2	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-1.282184735829051	[42]	[97]	-7	hSpCas9	negative selection	12273279
53382359	53382382	12	+	28162770	OCIAML2	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	-0.5385338897439648	[86]	[331]	-4	hSpCas9	negative selection	12273280
53383296	53383319	12	+	28162770	OCIAML2	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	-0.9753045370056816	[82]	[233]	-6	hSpCas9	negative selection	12273281
53381781	53381804	12	+	28162770	OCIAML2	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-2.5775450291586735	[13]	[12]	-8	hSpCas9	negative selection	12273282
53382590	53382613	12	+	28162770	OCIAML2	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	-0.5792106383960826	[99]	[370]	-4	hSpCas9	negative selection	12273283
53382935	53382958	12	+	28162770	OCIAML2	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	-0.4677473167090398	[124]	[500]	-4	hSpCas9	negative selection	12273284
53382999	53383022	12	+	28162770	OCIAML2	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	-0.4064994878224457	[76]	[321]	-3	hSpCas9	negative selection	12273285
53383058	53383081	12	+	28162770	OCIAML2	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-2.6930222465786096	[13]	[11]	-9	hSpCas9	negative selection	12273286
53406690	53406713	12	+	28162770	OCIAML3	viability	AAGCCGGTCGGAGGACCCGGCGG	SP1	ENSG00000185591	-0.8350157398279578	[12]	[21]	-6	hSpCas9	negative selection	12442643
53383180	53383203	12	-	28162770	OCIAML3	viability	GTGCTGCTTGGAGGGCCTGGAGG	SP1	ENSG00000185591	0.47814214543167216	[38]	[163]	4	hSpCas9	negative selection	12442644
53382173	53382196	12	+	28162770	OCIAML3	viability	GAGAACAGCAACAACTCCCAGGG	SP1	ENSG00000185591	-0.33766788706437756	[53]	[128]	-3	hSpCas9	negative selection	12442645
53382359	53382382	12	+	28162770	OCIAML3	viability	AAGAATCGCACAGTCTCTGGTGG	SP1	ENSG00000185591	1.011039106440325	[106]	[650]	8	hSpCas9	negative selection	12442646
53383296	53383319	12	+	28162770	OCIAML3	viability	TCATCCGGACACCAACAGTGGGG	SP1	ENSG00000185591	0.05591030223776294	[151]	[476]	0	hSpCas9	negative selection	12442647
53381781	53381804	12	+	28162770	OCIAML3	viability	GGCAGTAGCAGCAGCACTGGAGG	SP1	ENSG00000185591	-0.7768716974739738	[20]	[36]	-5	hSpCas9	negative selection	12442648
53382590	53382613	12	+	28162770	OCIAML3	viability	ATCACAAATCGAGGAAGTGGAGG	SP1	ENSG00000185591	0.5145168164540059	[143]	[620]	5	hSpCas9	negative selection	12442649
53382935	53382958	12	+	28162770	OCIAML3	viability	ACTACTACCACCAGCAACATGGG	SP1	ENSG00000185591	0.9626261373384986	[179]	[1058]	8	hSpCas9	negative selection	12442650
53382999	53383022	12	+	28162770	OCIAML3	viability	CTCAAGGCCAGACACCCCAGAGG	SP1	ENSG00000185591	0.5818421950752544	[134]	[609]	5	hSpCas9	negative selection	12442651
53383058	53383081	12	+	28162770	OCIAML3	viability	CAGCAAAACCAGACATCTGGAGG	SP1	ENSG00000185591	-1.1579085255174897	[16]	[22]	-7	hSpCas9	negative selection	12442652