| 21526911 | 21526934 | 12 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | AAACACCAGGAAAAGAGCCAAGG | SPX | ENSG00000134548 | -0.23035075689495213 | [3,3] | [3,1] | -3 | hSpCas9 | positive selection | 3023633 | 21527168 | 21527191 | 12 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | AGCTATGCTCTACCTGAAAGGGG | SPX | ENSG00000134548 | 0.33151299152701286 | [3,3] | [4,4] | 7 | hSpCas9 | positive selection | 3023634 | 21527734 | 21527757 | 12 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGCTCTGGTCGGAGATGAAGCGG | SPX | ENSG00000134548 | -0.3839210750602731 | [3,3] | [3,0] | -5 | hSpCas9 | positive selection | 3023635 | 21526924 | 21526947 | 12 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TTCCCAGGAAAACAAACACCAGG | SPX | ENSG00000134548 | 0.1929372869908701 | [5,5] | [5,5] | 4 | hSpCas9 | positive selection | 3023636 | 21526911 | 21526934 | 12 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | AAACACCAGGAAAAGAGCCAAGG | SPX | ENSG00000134548 | -0.4276002230065772 | [3,3] | [1,1] | -6 | hSpCas9 | positive selection | 3091491 | 21527168 | 21527191 | 12 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | AGCTATGCTCTACCTGAAAGGGG | SPX | ENSG00000134548 | -0.08979232437124585 | [3,3] | [4,1] | -1 | hSpCas9 | positive selection | 3091492 | 21527734 | 21527757 | 12 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGCTCTGGTCGGAGATGAAGCGG | SPX | ENSG00000134548 | -0.7107017709575807 | [3,3] | [2,0] | -8 | hSpCas9 | positive selection | 3091493 | 21526924 | 21526947 | 12 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TTCCCAGGAAAACAAACACCAGG | SPX | ENSG00000134548 | 0.26184214893645014 | [5,5] | [4,4] | 4 | hSpCas9 | positive selection | 3091494 | 21526911 | 21526934 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | AAACACCAGGAAAAGAGCCAAGG | SPX | ENSG00000134548 | 2.65771858452627 | [] | [] | 8 | hSpCas9 | negative selection | 3462302 | 21527167 | 21527190 | 12 | + | 26780180 | HT29 | viability (Avana library 4 designs) | AGCTATGCTCTACCTGAAAGGGG | SPX | ENSG00000134548 | -0.640685843728022 | [] | [] | -8 | hSpCas9 | negative selection | 3462303 | 21527734 | 21527757 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GGCTCTGGTCGGAGATGAAGCGG | SPX | ENSG00000134548 | 1.07858114494098 | [] | [] | 4 | hSpCas9 | negative selection | 3462304 | 21526924 | 21526947 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TTCCCAGGAAAACAAACACCAGG | SPX | ENSG00000134548 | -0.356713809657612 | [] | [] | -5 | hSpCas9 | negative selection | 3462305 | 21527167 | 21527190 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AGCTATGCTCTACCTGAAAGGGG | SPX | ENSG00000134548 | 3.54819604192134 | [] | [] | 5 | hSpCas9 | negative selection | 3563788 | 21526911 | 21526934 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AAACACCAGGAAAAGAGCCAAGG | SPX | ENSG00000134548 | 1.86273439588951 | [] | [] | 2 | hSpCas9 | negative selection | 3563789 | 21526924 | 21526947 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TTCCCAGGAAAACAAACACCAGG | SPX | ENSG00000134548 | -0.999741346539725 | [] | [] | -1 | hSpCas9 | negative selection | 3563790 | 21527734 | 21527757 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGCTCTGGTCGGAGATGAAGCGG | SPX | ENSG00000134548 | 1.15081001968457 | [] | [] | 1 | hSpCas9 | negative selection | 3563791 | 21527736 | 21527759 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -3.1813336666745 | [] | [] | -4 | hSpCas9 | negative selection | 3563792 | 21526894 | 21526917 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AAGTCTGGCAGCAACAACCTTGG | SPX | ENSG00000134548 | 2.69071805488209 | [] | [] | 4 | hSpCas9 | negative selection | 3563793 | 21527167 | 21527190 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | AGCTATGCTCTACCTGAAAGGGG | SPX | ENSG00000134548 | -4.25943984436811 | [] | [] | -7 | hSpCas9 | negative selection | 3672447 | 21526911 | 21526934 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | AAACACCAGGAAAAGAGCCAAGG | SPX | ENSG00000134548 | 2.13070452839618 | [] | [] | 2 | hSpCas9 | negative selection | 3672448 | 21526924 | 21526947 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | TTCCCAGGAAAACAAACACCAGG | SPX | ENSG00000134548 | -4.56071081256641 | [] | [] | -7 | hSpCas9 | negative selection | 3672449 | 21527734 | 21527757 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | GGCTCTGGTCGGAGATGAAGCGG | SPX | ENSG00000134548 | 2.82549520823988 | [] | [] | 3 | hSpCas9 | negative selection | 3672450 | 21527736 | 21527759 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -2.04305101011143 | [] | [] | -3 | hSpCas9 | negative selection | 3672451 | 21526894 | 21526917 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | AAGTCTGGCAGCAACAACCTTGG | SPX | ENSG00000134548 | 1.32474717687418 | [] | [] | 1 | hSpCas9 | negative selection | 3672452 | 21527167 | 21527190 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AGCTATGCTCTACCTGAAAGGGG | SPX | ENSG00000134548 | 0.10612027683036446 | [5] | [6,5] | 2 | hSpCas9 | positive selection | 3781054 | 21526911 | 21526934 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AAACACCAGGAAAAGAGCCAAGG | SPX | ENSG00000134548 | 0.07205271855435014 | [4] | [5,4] | 1 | hSpCas9 | positive selection | 3781055 | 21526924 | 21526947 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TTCCCAGGAAAACAAACACCAGG | SPX | ENSG00000134548 | -0.04151387818880961 | [5] | [5,5] | 0 | hSpCas9 | positive selection | 3781056 | 21527734 | 21527757 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGCTCTGGTCGGAGATGAAGCGG | SPX | ENSG00000134548 | 0.2449277720455479 | [4] | [6,4] | 7 | hSpCas9 | positive selection | 3781057 | 21527736 | 21527759 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.3741430242120796 | [4] | [2,2] | -5 | hSpCas9 | positive selection | 3781058 | 21526894 | 21526917 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AAGTCTGGCAGCAACAACCTTGG | SPX | ENSG00000134548 | 0.11025653093210913 | [5] | [5,6] | 3 | hSpCas9 | positive selection | 3781059 | 21527167 | 21527190 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AGCTATGCTCTACCTGAAAGGGG | SPX | ENSG00000134548 | -0.13954144720945247 | [5] | [3,4] | -2 | hSpCas9 | positive selection | 3889661 | 21526911 | 21526934 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AAACACCAGGAAAAGAGCCAAGG | SPX | ENSG00000134548 | -0.06593270266064256 | [5] | [4,3] | -1 | hSpCas9 | positive selection | 3889662 | 21526924 | 21526947 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TTCCCAGGAAAACAAACACCAGG | SPX | ENSG00000134548 | 0.23541784960346762 | [6] | [6,7] | 6 | hSpCas9 | positive selection | 3889663 | 21527734 | 21527757 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGCTCTGGTCGGAGATGAAGCGG | SPX | ENSG00000134548 | 0.10360764948061474 | [5] | [5,4] | 2 | hSpCas9 | positive selection | 3889664 | 21527736 | 21527759 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | 0.29000847559609694 | [5] | [6,4] | 7 | hSpCas9 | positive selection | 3889665 | 21526894 | 21526917 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AAGTCTGGCAGCAACAACCTTGG | SPX | ENSG00000134548 | 0.13612620613925536 | [6] | [5,6] | 3 | hSpCas9 | positive selection | 3889666 | 21526945 | 21526968 | 12 | + | 26780180 | A375 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.390385060879958 | [] | [] | 0 | hSpCas9 | negative selection | 3999357 | 21527165 | 21527188 | 12 | + | 26780180 | A375 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 1.08343012347603 | [] | [] | 5 | hSpCas9 | negative selection | 3999358 | 21527767 | 21527790 | 12 | + | 26780180 | A375 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.710548009059571 | [] | [] | 2 | hSpCas9 | negative selection | 3999359 | 21526950 | 21526973 | 12 | - | 26780180 | A375 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 1.59795252108322 | [] | [] | 8 | hSpCas9 | negative selection | 3999360 | 21527736 | 21527759 | 12 | + | 26780180 | A375 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | 0.429061378902098 | [] | [] | 1 | hSpCas9 | negative selection | 3999361 | 21529017 | 21529040 | 12 | + | 26780180 | A375 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 1.24811109617845 | [] | [] | 6 | hSpCas9 | negative selection | 3999362 | 21526945 | 21526968 | 12 | + | 26780180 | HT29 | viability (GeCKOv2 library) | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.629782705055551 | [] | [] | 2 | hSpCas9 | negative selection | 4107323 | 21527165 | 21527188 | 12 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.82760307506529 | [] | [] | 3 | hSpCas9 | negative selection | 4107324 | 21527767 | 21527790 | 12 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.508504629067905 | [] | [] | 1 | hSpCas9 | negative selection | 4107325 | 21526950 | 21526973 | 12 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 1.72004039180519 | [] | [] | 8 | hSpCas9 | negative selection | 4107326 | 21527736 | 21527759 | 12 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | 0.430319495698034 | [] | [] | 1 | hSpCas9 | negative selection | 4107327 | 21529017 | 21529040 | 12 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 1.5953201728109 | [] | [] | 8 | hSpCas9 | negative selection | 4107328 | 21527165 | 21527188 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.4007660026089044 | [3] | [3,3] | 8 | hSpCas9 | positive selection | 4183704 | 21526950 | 21526973 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | -0.18758598418274622 | [3] | [1,1] | -4 | hSpCas9 | positive selection | 4183715 | 21527179 | 21527202 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GGAACTTACGTGCCCCTTTCAGG | SPX | ENSG00000134548 | -0.3049427576412136 | [3] | [1,2] | -6 | hSpCas9 | positive selection | 4183726 | 21527165 | 21527188 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.2960585570094062 | [2] | [0,4,1,0] | 2 | hSpCas9 | positive selection | 4247726 | 21526950 | 21526973 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | -0.06327095433533947 | [1] | [0,0,0,0] | -1 | hSpCas9 | positive selection | 4247737 | 21527179 | 21527202 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GGAACTTACGTGCCCCTTTCAGG | SPX | ENSG00000134548 | -0.10425817291360501 | [3] | [1,1,1,0] | -1 | hSpCas9 | positive selection | 4247748 | 21526945 | 21526968 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.2837000949221342 | [2] | [3,1] | 6 | hSpCas9 | positive selection | 4258933 | 21526950 | 21526973 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | -0.3381549391985762 | [2] | [2,0] | -6 | hSpCas9 | positive selection | 4258934 | 21527165 | 21527188 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.5926638997545739 | [3] | [3,4] | 9 | hSpCas9 | positive selection | 4258935 | 21529017 | 21529040 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.1844018536473861 | [3] | [2,1] | -4 | hSpCas9 | positive selection | 4323215 | 21527767 | 21527790 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.4914107743629273 | [2] | [2,0] | -8 | hSpCas9 | positive selection | 4323216 | 21527736 | 21527759 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | 0.12594318030274776 | [4] | [3,2] | 2 | hSpCas9 | positive selection | 4323217 | 21526945 | 21526968 | 12 | + | 27260156 | BXPC3 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.4057147130017168 | [339] | [399,420,440,650] | 8 | hSpCas9 | negative selection | 5531393 | 21526950 | 21526973 | 12 | - | 27260156 | BXPC3 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.28000510484380564 | [397] | [388,431,574,658] | 6 | hSpCas9 | negative selection | 5531394 | 21527165 | 21527188 | 12 | + | 27260156 | BXPC3 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | -0.021324826310247236 | [645] | [563,703,588,827] | 0 | hSpCas9 | negative selection | 5531395 | 21529017 | 21529040 | 12 | + | 27260156 | BXPC3 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.03692377180811494 | [488] | [448,463,596,607] | 0 | hSpCas9 | negative selection | 5595675 | 21527767 | 21527790 | 12 | + | 27260156 | BXPC3 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.18510422967598056 | [319] | [378,369,404,363] | 4 | hSpCas9 | negative selection | 5595676 | 21527736 | 21527759 | 12 | + | 27260156 | BXPC3 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.12762314804149155 | [1024] | [962,962,992,1003] | -3 | hSpCas9 | negative selection | 5595677 | 21526945 | 21526968 | 12 | + | 27260156 | A673 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.4828023256671867 | [339] | [655,467,542,629] | 9 | hSpCas9 | negative selection | 5652644 | 21526950 | 21526973 | 12 | - | 27260156 | A673 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.07104089531425481 | [397] | [532,448,538,489] | 1 | hSpCas9 | negative selection | 5652645 | 21527165 | 21527188 | 12 | + | 27260156 | A673 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.16526754363922258 | [645] | [1031,787,851,823] | 4 | hSpCas9 | negative selection | 5652646 | 21529017 | 21529040 | 12 | + | 27260156 | A673 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.17773960111269996 | [488] | [540,501,462,575] | -4 | hSpCas9 | negative selection | 5716926 | 21527767 | 21527790 | 12 | + | 27260156 | A673 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.00195009291051651 | [319] | [457,347,322,416] | 0 | hSpCas9 | negative selection | 5716927 | 21527736 | 21527759 | 12 | + | 27260156 | A673 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.2149756444292238 | [1024] | [1082,907,984,1282] | -5 | hSpCas9 | negative selection | 5716928 | 21526945 | 21526968 | 12 | + | 27260156 | A375 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.6389729020729378 | [339] | [719,798,497,494] | 8 | hSpCas9 | negative selection | 5773895 | 21526950 | 21526973 | 12 | - | 27260156 | A375 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.23663685310885935 | [397] | [476,671,494,559] | 3 | hSpCas9 | negative selection | 5773896 | 21527165 | 21527188 | 12 | + | 27260156 | A375 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.09084948486444555 | [645] | [782,926,1045,507] | 1 | hSpCas9 | negative selection | 5773897 | 21529017 | 21529040 | 12 | + | 27260156 | A375 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.17919570382632535 | [488] | [658,815,653,496] | 2 | hSpCas9 | negative selection | 5838177 | 21527767 | 21527790 | 12 | + | 27260156 | A375 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.08211792963177389 | [319] | [259,581,303,452] | 1 | hSpCas9 | negative selection | 5838178 | 21527736 | 21527759 | 12 | + | 27260156 | A375 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.1367791102107735 | [1024] | [1149,1014,1165,1018] | -2 | hSpCas9 | negative selection | 5838179 | 21526945 | 21526968 | 12 | + | 27260156 | COLO741 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.48590241909996057 | [339] | [489,812,517] | 8 | hSpCas9 | negative selection | 5895146 | 21526950 | 21526973 | 12 | - | 27260156 | COLO741 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.13292560578763354 | [397] | [666,530,487] | 3 | hSpCas9 | negative selection | 5895147 | 21527165 | 21527188 | 12 | + | 27260156 | COLO741 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.2930777132475264 | [645] | [1262,1007,797] | 6 | hSpCas9 | negative selection | 5895148 | 21529017 | 21529040 | 12 | + | 27260156 | COLO741 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.02888637958881245 | [488] | [819,461,573] | 0 | hSpCas9 | negative selection | 5959428 | 21527767 | 21527790 | 12 | + | 27260156 | COLO741 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.19010942493051752 | [319] | [460,527,412] | 4 | hSpCas9 | negative selection | 5959429 | 21527736 | 21527759 | 12 | + | 27260156 | COLO741 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.2645281839935728 | [1024] | [1225,983,1070] | -5 | hSpCas9 | negative selection | 5959430 | 21526945 | 21526968 | 12 | + | 27260156 | CAL120 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.34413174049587236 | [339] | [568,465,579] | 5 | hSpCas9 | negative selection | 6016397 | 21526950 | 21526973 | 12 | - | 27260156 | CAL120 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.7376974131727762 | [397] | [1162,484,878] | 9 | hSpCas9 | negative selection | 6016398 | 21527165 | 21527188 | 12 | + | 27260156 | CAL120 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.484922061801501 | [645] | [1378,973,1060] | 7 | hSpCas9 | negative selection | 6016399 | 21529017 | 21529040 | 12 | + | 27260156 | CAL120 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.4663135388852233 | [488] | [400,405,506] | -6 | hSpCas9 | negative selection | 6080679 | 21527767 | 21527790 | 12 | + | 27260156 | CAL120 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.2824722826812961 | [319] | [529,292,191] | -4 | hSpCas9 | negative selection | 6080680 | 21527736 | 21527759 | 12 | + | 27260156 | CAL120 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.4649923110243279 | [1024] | [966,871,938] | -6 | hSpCas9 | negative selection | 6080681 | 21526945 | 21526968 | 12 | + | 27260156 | CADOES1 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.7997597408248767 | [339] | [476,419,595,714] | 9 | hSpCas9 | negative selection | 6137648 | 21526950 | 21526973 | 12 | - | 27260156 | CADOES1 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.3284419940096519 | [397] | [368,536,528,422] | 5 | hSpCas9 | negative selection | 6137649 | 21527165 | 21527188 | 12 | + | 27260156 | CADOES1 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.2472584754198932 | [645] | [610,745,753,742] | 4 | hSpCas9 | negative selection | 6137650 | 21529017 | 21529040 | 12 | + | 27260156 | CADOES1 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.20475132825451228 | [488] | [447,423,271,435] | -4 | hSpCas9 | negative selection | 6201930 | 21527767 | 21527790 | 12 | + | 27260156 | CADOES1 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.352597125072577 | [319] | [157,343,191,238] | -6 | hSpCas9 | negative selection | 6201931 | 21527736 | 21527759 | 12 | + | 27260156 | CADOES1 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.15273751841617145 | [1024] | [974,715,920,815] | -3 | hSpCas9 | negative selection | 6201932 | 21526945 | 21526968 | 12 | + | 27260156 | EWS502 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.39695302681417793 | [339] | [396,462,636,404] | 7 | hSpCas9 | negative selection | 6258899 | 21526950 | 21526973 | 12 | - | 27260156 | EWS502 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.15297737565006664 | [397] | [413,410,584,473] | 2 | hSpCas9 | negative selection | 6258900 | 21527165 | 21527188 | 12 | + | 27260156 | EWS502 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.07060428738432556 | [645] | [756,637,813,657] | 1 | hSpCas9 | negative selection | 6258901 | 21529017 | 21529040 | 12 | + | 27260156 | EWS502 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.013016727777862606 | [488] | [637,501,471,457] | 0 | hSpCas9 | negative selection | 6323181 | 21527767 | 21527790 | 12 | + | 27260156 | EWS502 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.2351136393554999 | [319] | [387,317,432,464] | 4 | hSpCas9 | negative selection | 6323182 | 21527736 | 21527759 | 12 | + | 27260156 | EWS502 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.3434055146909356 | [1024] | [790,785,856,1006] | -5 | hSpCas9 | negative selection | 6323183 | 21526945 | 21526968 | 12 | + | 27260156 | EW8 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.3939893515796026 | [339] | [316,387,351,386] | 7 | hSpCas9 | negative selection | 6380150 | 21526950 | 21526973 | 12 | - | 27260156 | EW8 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.10512634039653646 | [397] | [385,356,341,306] | 2 | hSpCas9 | negative selection | 6380151 | 21527165 | 21527188 | 12 | + | 27260156 | EW8 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.23272698022456229 | [645] | [728,643,560,546] | 4 | hSpCas9 | negative selection | 6380152 | 21529017 | 21529040 | 12 | + | 27260156 | EW8 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.06902425952478833 | [488] | [525,452,357,346] | 1 | hSpCas9 | negative selection | 6444432 | 21527767 | 21527790 | 12 | + | 27260156 | EW8 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.14287917055563298 | [319] | [355,405,155,256] | 2 | hSpCas9 | negative selection | 6444433 | 21527736 | 21527759 | 12 | + | 27260156 | EW8 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | 0.09408138064836091 | [1024] | [943,938,807,872] | 1 | hSpCas9 | negative selection | 6444434 | 21526945 | 21526968 | 12 | + | 27260156 | CORL105 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.3742049415572287 | [339] | [460,543,597,470] | 7 | hSpCas9 | negative selection | 6501401 | 21526950 | 21526973 | 12 | - | 27260156 | CORL105 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | -0.05509545512436456 | [397] | [327,467,505,495] | -1 | hSpCas9 | negative selection | 6501402 | 21527165 | 21527188 | 12 | + | 27260156 | CORL105 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.28084700021167985 | [645] | [951,727,1205,838] | 5 | hSpCas9 | negative selection | 6501403 | 21529017 | 21529040 | 12 | + | 27260156 | CORL105 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.15807078011686135 | [488] | [486,436,517,610] | -3 | hSpCas9 | negative selection | 6565683 | 21527767 | 21527790 | 12 | + | 27260156 | CORL105 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.43466681606597746 | [319] | [397,413,759,490] | 7 | hSpCas9 | negative selection | 6565684 | 21527736 | 21527759 | 12 | + | 27260156 | CORL105 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.25803527791386816 | [1024] | [901,947,1438,790] | -5 | hSpCas9 | negative selection | 6565685 | 21526945 | 21526968 | 12 | + | 27260156 | HS294T | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.5210222222358429 | [339] | [133,173,261,189] | 7 | hSpCas9 | negative selection | 6622652 | 21526950 | 21526973 | 12 | - | 27260156 | HS294T | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.35114301421806304 | [397] | [205,249,177,137] | 5 | hSpCas9 | negative selection | 6622653 | 21527165 | 21527188 | 12 | + | 27260156 | HS294T | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.35141212635008057 | [645] | [253,360,301,369] | 5 | hSpCas9 | negative selection | 6622654 | 21529017 | 21529040 | 12 | + | 27260156 | HS294T | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.08230248779305871 | [488] | [181,168,210,248] | 1 | hSpCas9 | negative selection | 6686934 | 21527767 | 21527790 | 12 | + | 27260156 | HS294T | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.2322684712183063 | [319] | [83,133,103,98] | -3 | hSpCas9 | negative selection | 6686935 | 21527736 | 21527759 | 12 | + | 27260156 | HS294T | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | 0.09317073172975321 | [1024] | [455,356,375,514] | 1 | hSpCas9 | negative selection | 6686936 | 21526945 | 21526968 | 12 | + | 27260156 | HCC44 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.3493764502534951 | [339] | [463,606,493,375] | 6 | hSpCas9 | negative selection | 6743903 | 21526950 | 21526973 | 12 | - | 27260156 | HCC44 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.350751956941828 | [397] | [570,520,780,464] | 6 | hSpCas9 | negative selection | 6743904 | 21527165 | 21527188 | 12 | + | 27260156 | HCC44 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.21594145887661864 | [645] | [797,780,960,870] | 3 | hSpCas9 | negative selection | 6743905 | 21529017 | 21529040 | 12 | + | 27260156 | HCC44 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.3132276880072382 | [488] | [699,744,608,668] | 5 | hSpCas9 | negative selection | 6808185 | 21527767 | 21527790 | 12 | + | 27260156 | HCC44 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.1397408119986564 | [319] | [287,439,438,414] | 2 | hSpCas9 | negative selection | 6808186 | 21527736 | 21527759 | 12 | + | 27260156 | HCC44 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.009391255756354244 | [1024] | [1329,1245,1124,902] | 0 | hSpCas9 | negative selection | 6808187 | 21526945 | 21526968 | 12 | + | 27260156 | G402 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.5355491249225529 | [339] | [786,243,922,461] | 6 | hSpCas9 | negative selection | 6865154 | 21526950 | 21526973 | 12 | - | 27260156 | G402 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.40605238629946777 | [397] | [966,533,300,801] | 5 | hSpCas9 | negative selection | 6865155 | 21527165 | 21527188 | 12 | + | 27260156 | G402 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.5632642704018817 | [645] | [1504,1061,911,1215] | 7 | hSpCas9 | negative selection | 6865156 | 21529017 | 21529040 | 12 | + | 27260156 | G402 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.372433751704438 | [488] | [1220,798,635,509] | 4 | hSpCas9 | negative selection | 6929436 | 21527767 | 21527790 | 12 | + | 27260156 | G402 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.11227669850278044 | [319] | [297,583,307,484] | 1 | hSpCas9 | negative selection | 6929437 | 21527736 | 21527759 | 12 | + | 27260156 | G402 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | 0.04145229385379112 | [1024] | [1383,1192,1326,1249] | 0 | hSpCas9 | negative selection | 6929438 | 21526945 | 21526968 | 12 | + | 27260156 | L33 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.6231916755413403 | [339] | [512,197,340,555] | 9 | hSpCas9 | negative selection | 6986405 | 21526950 | 21526973 | 12 | - | 27260156 | L33 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.18202266609212173 | [397] | [480,191,273,419] | 4 | hSpCas9 | negative selection | 6986406 | 21527165 | 21527188 | 12 | + | 27260156 | L33 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.03740379830110291 | [645] | [695,275,392,655] | 0 | hSpCas9 | negative selection | 6986407 | 21529017 | 21529040 | 12 | + | 27260156 | L33 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.04300326461801171 | [488] | [467,165,307,534] | -1 | hSpCas9 | negative selection | 7050687 | 21527767 | 21527790 | 12 | + | 27260156 | L33 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.2909748297359873 | [319] | [264,87,170,293] | -6 | hSpCas9 | negative selection | 7050688 | 21527736 | 21527759 | 12 | + | 27260156 | L33 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.31383631812766 | [1024] | [712,333,636,760] | -6 | hSpCas9 | negative selection | 7050689 | 21526945 | 21526968 | 12 | + | 27260156 | K562 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.47152917210137446 | [339] | [202,355,618,466] | 6 | hSpCas9 | negative selection | 7107656 | 21526950 | 21526973 | 12 | - | 27260156 | K562 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.38180334819523226 | [397] | [458,841,240,331] | 5 | hSpCas9 | negative selection | 7107657 | 21527165 | 21527188 | 12 | + | 27260156 | K562 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.7268151471347867 | [645] | [658,1074,1440,635] | 8 | hSpCas9 | negative selection | 7107658 | 21529017 | 21529040 | 12 | + | 27260156 | K562 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.08747096577720126 | [488] | [582,217,543,490] | 1 | hSpCas9 | negative selection | 7171938 | 21527767 | 21527790 | 12 | + | 27260156 | K562 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.18000405629599958 | [319] | [251,288,461,279] | 2 | hSpCas9 | negative selection | 7171939 | 21527736 | 21527759 | 12 | + | 27260156 | K562 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.45346697662099433 | [1024] | [495,1165,492,527] | -5 | hSpCas9 | negative selection | 7171940 | 21526945 | 21526968 | 12 | + | 27260156 | HT29 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.4156697721929211 | [339] | [624,527,626,438] | 7 | hSpCas9 | negative selection | 7228907 | 21526950 | 21526973 | 12 | - | 27260156 | HT29 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.3767267968068716 | [397] | [692,634,640,553] | 7 | hSpCas9 | negative selection | 7228908 | 21527165 | 21527188 | 12 | + | 27260156 | HT29 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.04771219770314661 | [645] | [948,879,748,693] | 0 | hSpCas9 | negative selection | 7228909 | 21529017 | 21529040 | 12 | + | 27260156 | HT29 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.11062931513273691 | [488] | [673,514,730,634] | 2 | hSpCas9 | negative selection | 7293189 | 21527767 | 21527790 | 12 | + | 27260156 | HT29 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.20596933820267005 | [319] | [580,571,360,314] | 4 | hSpCas9 | negative selection | 7293190 | 21527736 | 21527759 | 12 | + | 27260156 | HT29 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.043934958644189503 | [1024] | [1231,1236,1179,1183] | -1 | hSpCas9 | negative selection | 7293191 | 21526945 | 21526968 | 12 | + | 27260156 | MHHES1 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.17501225117912644 | [339] | [542,579,271,366] | 3 | hSpCas9 | negative selection | 7350158 | 21526950 | 21526973 | 12 | - | 27260156 | MHHES1 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.5587854342605196 | [397] | [692,748,586,618] | 8 | hSpCas9 | negative selection | 7350159 | 21527165 | 21527188 | 12 | + | 27260156 | MHHES1 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.5628893733473369 | [645] | [1186,1502,1090,650] | 8 | hSpCas9 | negative selection | 7350160 | 21529017 | 21529040 | 12 | + | 27260156 | MHHES1 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.1732755988759408 | [488] | [804,677,593,458] | 3 | hSpCas9 | negative selection | 7414440 | 21527767 | 21527790 | 12 | + | 27260156 | MHHES1 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.15842914291350957 | [319] | [421,391,410,380] | 3 | hSpCas9 | negative selection | 7414441 | 21527736 | 21527759 | 12 | + | 27260156 | MHHES1 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.13031225416174863 | [1024] | [1034,1105,936,1105] | -2 | hSpCas9 | negative selection | 7414442 | 21526945 | 21526968 | 12 | + | 27260156 | MEWO | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.5065685919418225 | [339] | [587,445,347] | 8 | hSpCas9 | negative selection | 7471409 | 21526950 | 21526973 | 12 | - | 27260156 | MEWO | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.1413902392853009 | [397] | [480,330,433] | 3 | hSpCas9 | negative selection | 7471410 | 21527165 | 21527188 | 12 | + | 27260156 | MEWO | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.10590080951768899 | [645] | [741,612,613] | 2 | hSpCas9 | negative selection | 7471411 | 21529017 | 21529040 | 12 | + | 27260156 | MEWO | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.03405429359429991 | [488] | [481,422,502] | 0 | hSpCas9 | negative selection | 7535691 | 21527767 | 21527790 | 12 | + | 27260156 | MEWO | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.45880126734185667 | [319] | [209,199,241] | -7 | hSpCas9 | negative selection | 7535692 | 21527736 | 21527759 | 12 | + | 27260156 | MEWO | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.6023649961695704 | [1024] | [617,656,616] | -8 | hSpCas9 | negative selection | 7535693 | 21526945 | 21526968 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.24575555976893962 | [339] | [433,306,418,310] | 4 | hSpCas9 | negative selection | 7592660 | 21526950 | 21526973 | 12 | - | 27260156 | LNCAPCLONEFGC | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | -0.09422096947830169 | [397] | [296,243,460,373] | -1 | hSpCas9 | negative selection | 7592661 | 21527165 | 21527188 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.25704752493326966 | [645] | [706,917,576,561] | 4 | hSpCas9 | negative selection | 7592662 | 21529017 | 21529040 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.05916960939699142 | [488] | [455,402,503,492] | 0 | hSpCas9 | negative selection | 7656942 | 21527767 | 21527790 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.1093271151152897 | [319] | [308,273,237,247] | -2 | hSpCas9 | negative selection | 7656943 | 21527736 | 21527759 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.13738694697978215 | [1024] | [772,750,1021,863] | -2 | hSpCas9 | negative selection | 7656944 | 21526945 | 21526968 | 12 | + | 27260156 | PANC0327 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.10377995007066154 | [339] | [371,253,289,394] | 1 | hSpCas9 | negative selection | 7713911 | 21526950 | 21526973 | 12 | - | 27260156 | PANC0327 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.06109775555997299 | [397] | [455,294,398,341] | 0 | hSpCas9 | negative selection | 7713912 | 21527165 | 21527188 | 12 | + | 27260156 | PANC0327 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | -0.09825651114906697 | [645] | [645,336,649,545] | -1 | hSpCas9 | negative selection | 7713913 | 21529017 | 21529040 | 12 | + | 27260156 | PANC0327 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.23197898332022998 | [488] | [312,449,219,480] | -3 | hSpCas9 | negative selection | 7778193 | 21527767 | 21527790 | 12 | + | 27260156 | PANC0327 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.40657146455403514 | [319] | [240,445,392,406] | 6 | hSpCas9 | negative selection | 7778194 | 21527736 | 21527759 | 12 | + | 27260156 | PANC0327 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.1545168774632415 | [1024] | [956,1059,678,555] | -2 | hSpCas9 | negative selection | 7778195 | 21526945 | 21526968 | 12 | + | 27260156 | NCIH2009 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.3982948471240322 | [339] | [868,579,476] | 5 | hSpCas9 | negative selection | 7835162 | 21526950 | 21526973 | 12 | - | 27260156 | NCIH2009 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | -0.09821362369984052 | [397] | [632,407,540] | -1 | hSpCas9 | negative selection | 7835163 | 21527165 | 21527188 | 12 | + | 27260156 | NCIH2009 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.3229639129961317 | [645] | [1068,812,1496] | 4 | hSpCas9 | negative selection | 7835164 | 21529017 | 21529040 | 12 | + | 27260156 | NCIH2009 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.4460666717989985 | [488] | [549,459,503] | -5 | hSpCas9 | negative selection | 7899444 | 21527767 | 21527790 | 12 | + | 27260156 | NCIH2009 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.2828000934203677 | [319] | [507,403,216] | -4 | hSpCas9 | negative selection | 7899445 | 21527736 | 21527759 | 12 | + | 27260156 | NCIH2009 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.5573318339305658 | [1024] | [1612,717,717] | -6 | hSpCas9 | negative selection | 7899446 | 21526945 | 21526968 | 12 | + | 27260156 | NCIH1373 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.4313299385025809 | [339] | [247,529,695,139] | 4 | hSpCas9 | negative selection | 7956413 | 21526950 | 21526973 | 12 | - | 27260156 | NCIH1373 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.17963654825215725 | [397] | [419,730,466,92] | 1 | hSpCas9 | negative selection | 7956414 | 21527165 | 21527188 | 12 | + | 27260156 | NCIH1373 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.5129693791954395 | [645] | [1053,860,1202,269] | 5 | hSpCas9 | negative selection | 7956415 | 21529017 | 21529040 | 12 | + | 27260156 | NCIH1373 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.33552622286351913 | [488] | [651,521,595,269] | 3 | hSpCas9 | negative selection | 8020695 | 21527767 | 21527790 | 12 | + | 27260156 | NCIH1373 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.39647605156965327 | [319] | [265,289,346,45] | -4 | hSpCas9 | negative selection | 8020696 | 21527736 | 21527759 | 12 | + | 27260156 | NCIH1373 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -1.0930011106156332 | [1024] | [502,538,415,183] | -8 | hSpCas9 | negative selection | 8020697 | 21526945 | 21526968 | 12 | + | 27260156 | PATU8902 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | -0.05241192901990738 | [339] | [506,214,492,615] | 0 | hSpCas9 | negative selection | 8077664 | 21526950 | 21526973 | 12 | - | 27260156 | PATU8902 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | -0.017761834974537677 | [397] | [520,834,354,522] | 0 | hSpCas9 | negative selection | 8077665 | 21527165 | 21527188 | 12 | + | 27260156 | PATU8902 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.0771541490051113 | [645] | [1040,1179,972,538] | 0 | hSpCas9 | negative selection | 8077666 | 21529017 | 21529040 | 12 | + | 27260156 | PATU8902 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.033658222100976666 | [488] | [747,1071,343,712] | 0 | hSpCas9 | negative selection | 8141946 | 21527767 | 21527790 | 12 | + | 27260156 | PATU8902 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.5417807111350827 | [319] | [357,288,287,288] | -5 | hSpCas9 | negative selection | 8141947 | 21527736 | 21527759 | 12 | + | 27260156 | PATU8902 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.47197091370645705 | [1024] | [817,1043,1189,1015] | -4 | hSpCas9 | negative selection | 8141948 | 21526945 | 21526968 | 12 | + | 27260156 | PANC1 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.6261599766452295 | [339] | [244,627,520,443] | 8 | hSpCas9 | negative selection | 8198915 | 21526950 | 21526973 | 12 | - | 27260156 | PANC1 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.4027954879716973 | [397] | [409,528,526,365] | 6 | hSpCas9 | negative selection | 8198916 | 21527165 | 21527188 | 12 | + | 27260156 | PANC1 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.2768344662043487 | [645] | [483,1027,688,570] | 4 | hSpCas9 | negative selection | 8198917 | 21529017 | 21529040 | 12 | + | 27260156 | PANC1 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.22353441326993778 | [488] | [359,567,582,465] | 3 | hSpCas9 | negative selection | 8263197 | 21527767 | 21527790 | 12 | + | 27260156 | PANC1 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.44719651307089325 | [319] | [166,279,252,131] | -6 | hSpCas9 | negative selection | 8263198 | 21527736 | 21527759 | 12 | + | 27260156 | PANC1 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.26971945792191376 | [1024] | [833,1116,569,501] | -4 | hSpCas9 | negative selection | 8263199 | 21526945 | 21526968 | 12 | + | 27260156 | PANC0813 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.48529984782389385 | [339] | [507,546,651,525] | 7 | hSpCas9 | negative selection | 8320166 | 21526950 | 21526973 | 12 | - | 27260156 | PANC0813 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.31048547366139506 | [397] | [639,635,602,451] | 5 | hSpCas9 | negative selection | 8320167 | 21527165 | 21527188 | 12 | + | 27260156 | PANC0813 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.019555714717462147 | [645] | [882,777,682,742] | 0 | hSpCas9 | negative selection | 8320168 | 21529017 | 21529040 | 12 | + | 27260156 | PANC0813 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.34418216144994296 | [488] | [416,474,513,402] | -5 | hSpCas9 | negative selection | 8384448 | 21527767 | 21527790 | 12 | + | 27260156 | PANC0813 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.06514794090678899 | [319] | [520,222,338,367] | -1 | hSpCas9 | negative selection | 8384449 | 21527736 | 21527759 | 12 | + | 27260156 | PANC0813 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.37422085016216966 | [1024] | [1143,867,802,918] | -5 | hSpCas9 | negative selection | 8384450 | 21526945 | 21526968 | 12 | + | 27260156 | RDES | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.35051530038478873 | [339] | [409,433,674,490] | 5 | hSpCas9 | negative selection | 8441417 | 21526950 | 21526973 | 12 | - | 27260156 | RDES | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.15012201615243723 | [397] | [369,482,646,562] | 2 | hSpCas9 | negative selection | 8441418 | 21527165 | 21527188 | 12 | + | 27260156 | RDES | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.017594888848881107 | [645] | [588,796,823,818] | 0 | hSpCas9 | negative selection | 8441419 | 21529017 | 21529040 | 12 | + | 27260156 | RDES | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.35168182283832006 | [488] | [426,565,1231,725] | 5 | hSpCas9 | negative selection | 8505699 | 21527767 | 21527790 | 12 | + | 27260156 | RDES | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.31130738365553556 | [319] | [412,384,555,481] | 5 | hSpCas9 | negative selection | 8505700 | 21527736 | 21527759 | 12 | + | 27260156 | RDES | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.1906299386279824 | [1024] | [781,1069,1073,1261] | -3 | hSpCas9 | negative selection | 8505701 | 21526945 | 21526968 | 12 | + | 27260156 | PC3 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.3092162920572358 | [339] | [318,363,641,440] | 6 | hSpCas9 | negative selection | 8562668 | 21526950 | 21526973 | 12 | - | 27260156 | PC3 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.2715881835753435 | [397] | [370,427,792,437] | 6 | hSpCas9 | negative selection | 8562669 | 21527165 | 21527188 | 12 | + | 27260156 | PC3 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | -0.11339078773139305 | [645] | [237,663,1011,748] | -3 | hSpCas9 | negative selection | 8562670 | 21529017 | 21529040 | 12 | + | 27260156 | PC3 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.008821481754212442 | [488] | [329,459,683,562] | 0 | hSpCas9 | negative selection | 8626950 | 21527767 | 21527790 | 12 | + | 27260156 | PC3 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.016798970516033407 | [319] | [192,262,594,378] | 0 | hSpCas9 | negative selection | 8626951 | 21527736 | 21527759 | 12 | + | 27260156 | PC3 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.14512315067350667 | [1024] | [501,919,1708,978] | -3 | hSpCas9 | negative selection | 8626952 | 21526945 | 21526968 | 12 | + | 27260156 | PATU8988T | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.7394098162976084 | [339] | [486,817,383,530] | 9 | hSpCas9 | negative selection | 8683919 | 21526950 | 21526973 | 12 | - | 27260156 | PATU8988T | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.20479704848605212 | [397] | [431,540,367,441] | 3 | hSpCas9 | negative selection | 8683920 | 21527165 | 21527188 | 12 | + | 27260156 | PATU8988T | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.4633963676835461 | [645] | [687,1037,705,1043] | 7 | hSpCas9 | negative selection | 8683921 | 21529017 | 21529040 | 12 | + | 27260156 | PATU8988T | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.18409665419858523 | [488] | [393,413,390,468] | -3 | hSpCas9 | negative selection | 8748201 | 21527767 | 21527790 | 12 | + | 27260156 | PATU8988T | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.12380911034982067 | [319] | [366,464,149,383] | 2 | hSpCas9 | negative selection | 8748202 | 21527736 | 21527759 | 12 | + | 27260156 | PATU8988T | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.2758241478669282 | [1024] | [613,790,872,1005] | -5 | hSpCas9 | negative selection | 8748203 | 21526945 | 21526968 | 12 | + | 27260156 | T47D | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.28168803893808975 | [339] | [534,417,503,473] | 6 | hSpCas9 | negative selection | 8805170 | 21526950 | 21526973 | 12 | - | 27260156 | T47D | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.24681346125549125 | [397] | [594,412,531,676] | 5 | hSpCas9 | negative selection | 8805171 | 21527165 | 21527188 | 12 | + | 27260156 | T47D | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.18209744762122237 | [645] | [932,781,763,946] | 4 | hSpCas9 | negative selection | 8805172 | 21529017 | 21529040 | 12 | + | 27260156 | T47D | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.06050251813296687 | [488] | [701,423,612,653] | 1 | hSpCas9 | negative selection | 8869452 | 21527767 | 21527790 | 12 | + | 27260156 | T47D | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | -0.12311738208645095 | [319] | [320,294,372,384] | -3 | hSpCas9 | negative selection | 8869453 | 21527736 | 21527759 | 12 | + | 27260156 | T47D | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.07976805929504449 | [1024] | [1246,1092,1074,1107] | -2 | hSpCas9 | negative selection | 8869454 | 21526945 | 21526968 | 12 | + | 27260156 | SU8686 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.5831492407156524 | [339] | [513,380,528,627] | 8 | hSpCas9 | negative selection | 8926421 | 21526950 | 21526973 | 12 | - | 27260156 | SU8686 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.10782670635544953 | [397] | [392,434,376,506] | 1 | hSpCas9 | negative selection | 8926422 | 21527165 | 21527188 | 12 | + | 27260156 | SU8686 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.1525387086691432 | [645] | [726,686,623,820] | 2 | hSpCas9 | negative selection | 8926423 | 21529017 | 21529040 | 12 | + | 27260156 | SU8686 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.2008700222629214 | [488] | [573,435,580,665] | 3 | hSpCas9 | negative selection | 8990703 | 21527767 | 21527790 | 12 | + | 27260156 | SU8686 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.07591516174383517 | [319] | [253,226,357,555] | 1 | hSpCas9 | negative selection | 8990704 | 21527736 | 21527759 | 12 | + | 27260156 | SU8686 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.23917686939907679 | [1024] | [944,662,870,996] | -4 | hSpCas9 | negative selection | 8990705 | 21526945 | 21526968 | 12 | + | 27260156 | SKES1 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.6169445832584042 | [339] | [510,631,440,505] | 9 | hSpCas9 | negative selection | 9047672 | 21526950 | 21526973 | 12 | - | 27260156 | SKES1 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | -0.006267922106991675 | [397] | [341,402,418,404] | 0 | hSpCas9 | negative selection | 9047673 | 21527165 | 21527188 | 12 | + | 27260156 | SKES1 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.13775180529520792 | [645] | [856,829,588,601] | 3 | hSpCas9 | negative selection | 9047674 | 21529017 | 21529040 | 12 | + | 27260156 | SKES1 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.05880725486918493 | [488] | [564,480,550,441] | 1 | hSpCas9 | negative selection | 9111954 | 21527767 | 21527790 | 12 | + | 27260156 | SKES1 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.36679890778273294 | [319] | [561,447,387,284] | 7 | hSpCas9 | negative selection | 9111955 | 21527736 | 21527759 | 12 | + | 27260156 | SKES1 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.04000751403140357 | [1024] | [1116,1255,907,763] | -1 | hSpCas9 | negative selection | 9111956 | 21526945 | 21526968 | 12 | + | 27260156 | TOV112D | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.7589331639395321 | [339] | [549,763,600,436] | 9 | hSpCas9 | negative selection | 9168923 | 21526950 | 21526973 | 12 | - | 27260156 | TOV112D | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.12394815152245088 | [397] | [338,678,337,432] | 2 | hSpCas9 | negative selection | 9168924 | 21527165 | 21527188 | 12 | + | 27260156 | TOV112D | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.08046660418278484 | [645] | [752,854,520,654] | 1 | hSpCas9 | negative selection | 9168925 | 21529017 | 21529040 | 12 | + | 27260156 | TOV112D | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.07976847173463003 | [488] | [369,707,581,445] | 1 | hSpCas9 | negative selection | 9233205 | 21527767 | 21527790 | 12 | + | 27260156 | TOV112D | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.023203499488887114 | [319] | [427,370,269,254] | 0 | hSpCas9 | negative selection | 9233206 | 21527736 | 21527759 | 12 | + | 27260156 | TOV112D | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | 0.009321097501688858 | [1024] | [1130,987,926,1080] | 0 | hSpCas9 | negative selection | 9233207 | 21526945 | 21526968 | 12 | + | 27260156 | TC71 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.29598467417329954 | [339] | [352,372,537,529] | 7 | hSpCas9 | negative selection | 9290174 | 21526950 | 21526973 | 12 | - | 27260156 | TC71 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.18642222486020937 | [397] | [618,462,419,435] | 4 | hSpCas9 | negative selection | 9290175 | 21527165 | 21527188 | 12 | + | 27260156 | TC71 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | 0.08446755783847903 | [645] | [787,713,697,736] | 2 | hSpCas9 | negative selection | 9290176 | 21529017 | 21529040 | 12 | + | 27260156 | TC71 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | -0.2593546698458863 | [488] | [445,430,451,420] | -6 | hSpCas9 | negative selection | 9354456 | 21527767 | 21527790 | 12 | + | 27260156 | TC71 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.25985790322214625 | [319] | [472,420,356,390] | 6 | hSpCas9 | negative selection | 9354457 | 21527736 | 21527759 | 12 | + | 27260156 | TC71 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.27250520435415604 | [1024] | [1062,859,928,773] | -6 | hSpCas9 | negative selection | 9354458 | 21526945 | 21526968 | 12 | + | 27260156 | TC32 | viability | AAACTCCAGCTGCGCTCCGCAGG | SPX | ENSG00000134548 | 0.6061274212622044 | [339] | [500,313,671,527] | 8 | hSpCas9 | negative selection | 9411425 | 21526950 | 21526973 | 12 | - | 27260156 | TC32 | viability | GATTACCTGCGGAGCGCAGCTGG | SPX | ENSG00000134548 | 0.5999829550749326 | [397] | [434,670,606,495] | 8 | hSpCas9 | negative selection | 9411426 | 21527165 | 21527188 | 12 | + | 27260156 | TC32 | viability | CAAGCTATGCTCTACCTGAAAGG | SPX | ENSG00000134548 | -0.16395986154360576 | [645] | [486,354,729,682] | -3 | hSpCas9 | negative selection | 9411427 | 21529017 | 21529040 | 12 | + | 27260156 | TC32 | viability | TCCCCAACTACTAACTATTCCGG | SPX | ENSG00000134548 | 0.014486462103570165 | [488] | [325,477,457,582] | 0 | hSpCas9 | negative selection | 9475707 | 21527767 | 21527790 | 12 | + | 27260156 | TC32 | viability | CCTCTCCGACCGGCCACTGCCGG | SPX | ENSG00000134548 | 0.15712500648401584 | [319] | [303,309,396,332] | 3 | hSpCas9 | negative selection | 9475708 | 21527736 | 21527759 | 12 | + | 27260156 | TC32 | viability | GCTTCATCTCCGACCAGAGCCGG | SPX | ENSG00000134548 | -0.3641872144653413 | [1024] | [666,616,930,828] | -6 | hSpCas9 | negative selection | 9475709 |