Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6853
• Symbol:Syn1
• Description:synapsin I

DataSource: http://genomecrispr.dkfz.de/#!/results/Syn1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
47619375	47619398	X	+	26472758	Jiyoye	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	0.4722704097277581	[64]	[67]	3	hSpCas9	negative selection	159566
47576150	47576173	X	-	26472758	Jiyoye	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	-0.2808806121793862	[173]	[107]	-2	hSpCas9	negative selection	159567
47619564	47619587	X	+	26472758	Jiyoye	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	-0.003893215570024977	[241]	[181]	0	hSpCas9	negative selection	159568
47619458	47619481	X	-	26472758	Jiyoye	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.9690542691139883	[41]	[61]	6	hSpCas9	negative selection	159569
47605291	47605314	X	+	26472758	Jiyoye	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.38208440054304293	[57]	[56]	3	hSpCas9	negative selection	159570
47605226	47605249	X	-	26472758	Jiyoye	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	0.5107980125800309	[93]	[100]	4	hSpCas9	negative selection	159571
47577477	47577500	X	-	26472758	Jiyoye	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	-1.0942224025761516	[217]	[76]	-6	hSpCas9	negative selection	159572
47577444	47577467	X	-	26472758	Jiyoye	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	-0.4307678603851538	[142]	[79]	-3	hSpCas9	negative selection	159573
47576221	47576244	X	-	26472758	Jiyoye	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.04607668933783332	[139]	[108]	0	hSpCas9	negative selection	159574
47576172	47576195	X	-	26472758	Jiyoye	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	-0.08262988617494271	[197]	[140]	0	hSpCas9	negative selection	159575
47583421	47583444	X	-	26472758	Jiyoye	viability	CAGAAGCCAGGGGCTCAAAGGGG	SYN1	ENSG00000008056	2.7994928042846334	[7]	[41]	9	hSpCas9	negative selection	165774
47583472	47583495	X	-	26472758	Jiyoye	viability	CACAGGTGCAGGCCCTGCTGGGG	SYN1	ENSG00000008056	-0.8004200379024939	[96]	[41]	-5	hSpCas9	negative selection	165775
47583431	47583454	X	-	26472758	Jiyoye	viability	AACAGGATGCCAGAAGCCAGGGG	SYN1	ENSG00000008056	-0.8096360075672747	[171]	[73]	-5	hSpCas9	negative selection	165776
47583497	47583520	X	-	26472758	Jiyoye	viability	AAGGCCGTCTGTGGGTGGGGTGG	SYN1	ENSG00000008056	0.7002806412274816	[181]	[222]	5	hSpCas9	negative selection	165777
47585294	47585317	X	+	26472758	Jiyoye	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.21873029209276318	[48]	[42]	1	hSpCas9	negative selection	165778
47585603	47585626	X	+	26472758	Jiyoye	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.8525865298282361	[46]	[63]	6	hSpCas9	negative selection	165779
47583483	47583506	X	-	26472758	Jiyoye	viability	GTGGGGTGGGACACAGGTGCAGG	SYN1	ENSG00000008056	-0.5016767304359311	[91]	[48]	-4	hSpCas9	negative selection	165780
47585236	47585259	X	-	26472758	Jiyoye	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	6.429543194534327	[0]	[64]	9	hSpCas9	negative selection	165781
47585576	47585599	X	-	26472758	Jiyoye	viability	CCAGGGAGCCACAAAACTGCAGG	SYN1	ENSG00000008056	0.017228863189859944	[75]	[57]	0	hSpCas9	negative selection	165782
47585622	47585645	X	-	26472758	Jiyoye	viability	TGTAGGTCTTGGTGAAGCCCCGG	SYN1	ENSG00000008056	-0.2680978902540909	[205]	[128]	-2	hSpCas9	negative selection	165783
47619375	47619398	X	+	26472758	KBM7	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-0.5741701674453893	[380,261]	[116,84]	-5	hSpCas9	negative selection	350684
47576150	47576173	X	-	26472758	KBM7	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	0.4295924040911082	[784,779]	[718,299]	4	hSpCas9	negative selection	350685
47619564	47619587	X	+	26472758	KBM7	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	-0.08478818743473493	[831,530]	[347,250]	-1	hSpCas9	negative selection	350686
47619458	47619481	X	-	26472758	KBM7	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.2372595140249153	[324,207]	[161,129]	2	hSpCas9	negative selection	350687
47605291	47605314	X	+	26472758	KBM7	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.5344401698341568	[221,235]	[228,92]	6	hSpCas9	negative selection	350688
47605226	47605249	X	-	26472758	KBM7	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	0.1774347387625932	[409,274]	[191,167]	1	hSpCas9	negative selection	350689
47577477	47577500	X	-	26472758	KBM7	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.972000420848747	[421,244]	[267,329]	9	hSpCas9	negative selection	350690
47577444	47577467	X	-	26472758	KBM7	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	1.0836347666228359	[193,299]	[219,281]	9	hSpCas9	negative selection	350691
47576221	47576244	X	-	26472758	KBM7	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.24335864897115056	[589,679]	[315,394]	2	hSpCas9	negative selection	350692
47576172	47576195	X	-	26472758	KBM7	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	0.48726347023456734	[575,391]	[335,294]	5	hSpCas9	negative selection	350693
47583421	47583444	X	-	26472758	KBM7	viability	CAGAAGCCAGGGGCTCAAAGGGG	SYN1	ENSG00000008056	0.37615658622869375	[160,131]	[127,53]	4	hSpCas9	negative selection	356892
47583472	47583495	X	-	26472758	KBM7	viability	CACAGGTGCAGGCCCTGCTGGGG	SYN1	ENSG00000008056	-0.1580458107190219	[262,167]	[56,117]	-1	hSpCas9	negative selection	356893
47583431	47583454	X	-	26472758	KBM7	viability	AACAGGATGCCAGAAGCCAGGGG	SYN1	ENSG00000008056	0.16673221374189862	[407,273]	[219,138]	1	hSpCas9	negative selection	356894
47583497	47583520	X	-	26472758	KBM7	viability	AAGGCCGTCTGTGGGTGGGGTGG	SYN1	ENSG00000008056	0.119886234992292	[1029,605]	[476,347]	1	hSpCas9	negative selection	356895
47585294	47585317	X	+	26472758	KBM7	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.5278532247860972	[223,111]	[99,119]	6	hSpCas9	negative selection	356896
47585603	47585626	X	+	26472758	KBM7	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.6590773744410473	[400,173]	[52,108]	-5	hSpCas9	negative selection	356897
47583483	47583506	X	-	26472758	KBM7	viability	GTGGGGTGGGACACAGGTGCAGG	SYN1	ENSG00000008056	-0.19636357915648606	[354,325]	[86,186]	-2	hSpCas9	negative selection	356898
47585236	47585259	X	-	26472758	KBM7	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.25401222911136656	[346,215]	[110,106]	-2	hSpCas9	negative selection	356899
47585576	47585599	X	-	26472758	KBM7	viability	CCAGGGAGCCACAAAACTGCAGG	SYN1	ENSG00000008056	0.544439845714739	[351,302]	[271,180]	6	hSpCas9	negative selection	356900
47585622	47585645	X	-	26472758	KBM7	viability	TGTAGGTCTTGGTGAAGCCCCGG	SYN1	ENSG00000008056	0.16399137925444351	[665,740]	[290,448]	1	hSpCas9	negative selection	356901
47619375	47619398	X	+	26472758	Raji	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-2.232466467511025	[161]	[7]	-9	hSpCas9	negative selection	541802
47576150	47576173	X	-	26472758	Raji	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	0.976139002095347	[321]	[146]	8	hSpCas9	negative selection	541803
47619564	47619587	X	+	26472758	Raji	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	-0.11896689953153172	[364]	[77]	-1	hSpCas9	negative selection	541804
47619458	47619481	X	-	26472758	Raji	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	1.0199206941232601	[84]	[39]	8	hSpCas9	negative selection	541805
47605291	47605314	X	+	26472758	Raji	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.5308826134006395	[169]	[56]	5	hSpCas9	negative selection	541806
47605226	47605249	X	-	26472758	Raji	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	1.7899013455174293	[161]	[129]	9	hSpCas9	negative selection	541807
47577477	47577500	X	-	26472758	Raji	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.4049274716340027	[178]	[54]	4	hSpCas9	negative selection	541808
47577444	47577467	X	-	26472758	Raji	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	-1.4548588888474734	[188]	[15]	-7	hSpCas9	negative selection	541809
47576221	47576244	X	-	26472758	Raji	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.7280051683023373	[332]	[127]	6	hSpCas9	negative selection	541810
47576172	47576195	X	-	26472758	Raji	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	-1.0254282930516134	[306]	[34]	-6	hSpCas9	negative selection	541811
47583421	47583444	X	-	26472758	Raji	viability	CAGAAGCCAGGGGCTCAAAGGGG	SYN1	ENSG00000008056	-0.40451550315783313	[153]	[26]	-3	hSpCas9	negative selection	548010
47583472	47583495	X	-	26472758	Raji	viability	CACAGGTGCAGGCCCTGCTGGGG	SYN1	ENSG00000008056	-0.5219730847060102	[98]	[15]	-4	hSpCas9	negative selection	548011
47583431	47583454	X	-	26472758	Raji	viability	AACAGGATGCCAGAAGCCAGGGG	SYN1	ENSG00000008056	0.7984332944844472	[165]	[66]	7	hSpCas9	negative selection	548012
47583497	47583520	X	-	26472758	Raji	viability	AAGGCCGTCTGTGGGTGGGGTGG	SYN1	ENSG00000008056	0.8940362536401585	[370]	[159]	7	hSpCas9	negative selection	548013
47585294	47585317	X	+	26472758	Raji	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.12291408404819482	[121]	[25]	-1	hSpCas9	negative selection	548014
47585603	47585626	X	+	26472758	Raji	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.45530683879390654	[131]	[41]	4	hSpCas9	negative selection	548015
47583483	47583506	X	-	26472758	Raji	viability	GTGGGGTGGGACACAGGTGCAGG	SYN1	ENSG00000008056	-1.5230936245999254	[160]	[12]	-8	hSpCas9	negative selection	548016
47585236	47585259	X	-	26472758	Raji	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.29024759252341004	[73]	[20]	2	hSpCas9	negative selection	548017
47585576	47585599	X	-	26472758	Raji	viability	CCAGGGAGCCACAAAACTGCAGG	SYN1	ENSG00000008056	0.28679278615930115	[218]	[61]	2	hSpCas9	negative selection	548018
47585622	47585645	X	-	26472758	Raji	viability	TGTAGGTCTTGGTGAAGCCCCGG	SYN1	ENSG00000008056	-0.2937147729473706	[411]	[77]	-2	hSpCas9	negative selection	548019
47619375	47619398	X	+	26472758	K562	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	0.24441872766644696	[269]	[269]	1	hSpCas9	negative selection	732920
47576150	47576173	X	-	26472758	K562	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	-0.16004357031025362	[588]	[444]	-1	hSpCas9	negative selection	732921
47619564	47619587	X	+	26472758	K562	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	0.4554063857306454	[507]	[587]	3	hSpCas9	negative selection	732922
47619458	47619481	X	-	26472758	K562	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	1.2972706099321818	[133]	[277]	9	hSpCas9	negative selection	732923
47605291	47605314	X	+	26472758	K562	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.7919065229689403	[181]	[265]	6	hSpCas9	negative selection	732924
47605226	47605249	X	-	26472758	K562	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	0.26678654069490126	[319]	[324]	2	hSpCas9	negative selection	732925
47577477	47577500	X	-	26472758	K562	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.010621543057749538	[253]	[215]	0	hSpCas9	negative selection	732926
47577444	47577467	X	-	26472758	K562	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	0.2015632487046498	[204]	[198]	1	hSpCas9	negative selection	732927
47576221	47576244	X	-	26472758	K562	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.47177345989649044	[538]	[630]	4	hSpCas9	negative selection	732928
47576172	47576195	X	-	26472758	K562	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	-0.6092918300828968	[505]	[279]	-4	hSpCas9	negative selection	732929
47583421	47583444	X	-	26472758	K562	viability	CAGAAGCCAGGGGCTCAAAGGGG	SYN1	ENSG00000008056	-1.1068036740149538	[198]	[77]	-6	hSpCas9	negative selection	739128
47583472	47583495	X	-	26472758	K562	viability	CACAGGTGCAGGCCCTGCTGGGG	SYN1	ENSG00000008056	-0.20649580794099354	[189]	[138]	-1	hSpCas9	negative selection	739129
47583431	47583454	X	-	26472758	K562	viability	AACAGGATGCCAGAAGCCAGGGG	SYN1	ENSG00000008056	0.13998131747345274	[357]	[332]	1	hSpCas9	negative selection	739130
47583497	47583520	X	-	26472758	K562	viability	AAGGCCGTCTGTGGGTGGGGTGG	SYN1	ENSG00000008056	1.4459419569552956	[566]	[1303]	9	hSpCas9	negative selection	739131
47585294	47585317	X	+	26472758	K562	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.4753731625063188	[143]	[168]	4	hSpCas9	negative selection	739132
47585603	47585626	X	+	26472758	K562	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.32442410769143226	[177]	[119]	-2	hSpCas9	negative selection	739133
47583483	47583506	X	-	26472758	K562	viability	GTGGGGTGGGACACAGGTGCAGG	SYN1	ENSG00000008056	-1.64415998966513	[273]	[73]	-7	hSpCas9	negative selection	739134
47585236	47585259	X	-	26472758	K562	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.5150663176101158	[251]	[303]	4	hSpCas9	negative selection	739135
47585576	47585599	X	-	26472758	K562	viability	CCAGGGAGCCACAAAACTGCAGG	SYN1	ENSG00000008056	1.8924912722422413	[163]	[513]	9	hSpCas9	negative selection	739136
47585622	47585645	X	-	26472758	K562	viability	TGTAGGTCTTGGTGAAGCCCCGG	SYN1	ENSG00000008056	0.3671617923786864	[517]	[563]	3	hSpCas9	negative selection	739137
47576154	47576177	X	-	26627737	DLD1	viability	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.6990057888397098	[283]	[119,247,78]	7	hSpCas9	negative selection	845745
47576328	47576351	X	-	26627737	DLD1	viability	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-0.7157711516373721	[447]	[102,124,36]	-6	hSpCas9	negative selection	845746
47605034	47605057	X	-	26627737	DLD1	viability	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.22368567371287407	[306]	[99,131,105]	2	hSpCas9	negative selection	845747
47605320	47605343	X	-	26627737	DLD1	viability	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.06416113151166303	[623]	[156,165,275]	0	hSpCas9	negative selection	845748
47606985	47607008	X	+	26627737	DLD1	viability	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.17794937779565934	[870]	[337,272,310]	1	hSpCas9	negative selection	845749
47619689	47619712	X	+	26627737	DLD1	viability	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	1.2413704001071548	[344]	[162,384,226]	9	hSpCas9	negative selection	845750
47576154	47576177	X	-	26627737	GBM cells	viability after 5 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	-0.277512692498582	[138]	[73,48]	-4	hSpCas9	negative selection	928060
47576328	47576351	X	-	26627737	GBM cells	viability after 5 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.3352461525277577	[268]	[198,164]	5	hSpCas9	negative selection	928061
47605034	47605057	X	-	26627737	GBM cells	viability after 5 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	-0.12746154053861172	[275]	[138,131]	-2	hSpCas9	negative selection	928062
47605320	47605343	X	-	26627737	GBM cells	viability after 5 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.07564405423311238	[375]	[219,204]	1	hSpCas9	negative selection	928063
47606985	47607008	X	+	26627737	GBM cells	viability after 5 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.06824284449101792	[537]	[297,306]	1	hSpCas9	negative selection	928064
47619689	47619712	X	+	26627737	GBM cells	viability after 5 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	-0.2547093142275263	[296]	[119,146]	-4	hSpCas9	negative selection	928065
47576154	47576177	X	-	26627737	GBM cells	viability after 13 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.2265662145655052	[138]	[90,85]	3	hSpCas9	negative selection	1010375
47576328	47576351	X	-	26627737	GBM cells	viability after 13 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.2948120716285507	[268]	[199,161]	4	hSpCas9	negative selection	1010376
47605034	47605057	X	-	26627737	GBM cells	viability after 13 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.12640105056697182	[275]	[195,136]	1	hSpCas9	negative selection	1010377
47605320	47605343	X	-	26627737	GBM cells	viability after 13 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.09958621703312365	[375]	[222,214]	1	hSpCas9	negative selection	1010378
47606985	47607008	X	+	26627737	GBM cells	viability after 13 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.0917525857486785	[537]	[320,302]	1	hSpCas9	negative selection	1010379
47619689	47619712	X	+	26627737	GBM cells	viability after 13 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	-0.07510551587645739	[296]	[163,143]	-1	hSpCas9	negative selection	1010380
47576154	47576177	X	-	26627737	GBM cells	viability after 21 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.29024549128674126	[138]	[95,88]	3	hSpCas9	negative selection	1092690
47576328	47576351	X	-	26627737	GBM cells	viability after 21 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.20613658320197287	[268]	[189,148]	2	hSpCas9	negative selection	1092691
47605034	47605057	X	-	26627737	GBM cells	viability after 21 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.0851965749241988	[275]	[180,138]	0	hSpCas9	negative selection	1092692
47605320	47605343	X	-	26627737	GBM cells	viability after 21 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.12841210049997343	[375]	[239,207]	1	hSpCas9	negative selection	1092693
47606985	47607008	X	+	26627737	GBM cells	viability after 21 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.27881966307036055	[537]	[363,345]	3	hSpCas9	negative selection	1092694
47619689	47619712	X	+	26627737	GBM cells	viability after 21 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.463647747566018	[296]	[233,211]	5	hSpCas9	negative selection	1092695
47576154	47576177	X	-	26627737	RPE1	viability after 9 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	1.3587621821348137	[292]	[112,392]	7	hSpCas9	negative selection	1175005
47576328	47576351	X	-	26627737	RPE1	viability after 9 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-1.28677587941938	[687]	[41,147]	-7	hSpCas9	negative selection	1175006
47605034	47605057	X	-	26627737	RPE1	viability after 9 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.5946366046676235	[709]	[322,351]	4	hSpCas9	negative selection	1175007
47605320	47605343	X	-	26627737	RPE1	viability after 9 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.7666195301152225	[1221]	[580,740]	5	hSpCas9	negative selection	1175008
47606985	47607008	X	+	26627737	RPE1	viability after 9 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.20913187861246985	[1594]	[633,503]	1	hSpCas9	negative selection	1175009
47619689	47619712	X	+	26627737	RPE1	viability after 9 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	-0.5245199446775975	[1234]	[163,403]	-4	hSpCas9	negative selection	1175010
47576154	47576177	X	-	26627737	RPE1	viability after 12 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	1.0232826521382523	[292]	[108,213]	6	hSpCas9	negative selection	1257320
47576328	47576351	X	-	26627737	RPE1	viability after 12 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-0.4085458242505861	[687]	[198,75]	-3	hSpCas9	negative selection	1257321
47605034	47605057	X	-	26627737	RPE1	viability after 12 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	1.0283803981876891	[709]	[425,349]	6	hSpCas9	negative selection	1257322
47605320	47605343	X	-	26627737	RPE1	viability after 12 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.7332359023547204	[1221]	[486,607]	5	hSpCas9	negative selection	1257323
47606985	47607008	X	+	26627737	RPE1	viability after 12 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	-0.2605653721040797	[1594]	[347,367]	-2	hSpCas9	negative selection	1257324
47619689	47619712	X	+	26627737	RPE1	viability after 12 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	-0.49836875350416265	[1234]	[179,292]	-3	hSpCas9	negative selection	1257325
47576154	47576177	X	-	26627737	RPE1	viability after 15 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.7932175971307092	[292]	[79,204]	5	hSpCas9	negative selection	1339635
47576328	47576351	X	-	26627737	RPE1	viability after 15 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.03304335604898148	[687]	[219,178]	0	hSpCas9	negative selection	1339636
47605034	47605057	X	-	26627737	RPE1	viability after 15 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.6305190408485916	[709]	[342,279]	4	hSpCas9	negative selection	1339637
47605320	47605343	X	-	26627737	RPE1	viability after 15 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.7534339893495632	[1221]	[540,622]	4	hSpCas9	negative selection	1339638
47606985	47607008	X	+	26627737	RPE1	viability after 15 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	-1.0392619334456656	[1594]	[132,302]	-6	hSpCas9	negative selection	1339639
47619689	47619712	X	+	26627737	RPE1	viability after 15 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	-0.9491334281402817	[1234]	[183,177]	-5	hSpCas9	negative selection	1339640
47576154	47576177	X	-	26627737	RPE1	viability after 18 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	1.2600089708850457	[292]	[141,239]	7	hSpCas9	negative selection	1421950
47576328	47576351	X	-	26627737	RPE1	viability after 18 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-0.34742772749770184	[687]	[143,147]	-2	hSpCas9	negative selection	1421951
47605034	47605057	X	-	26627737	RPE1	viability after 18 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.9388770066958416	[709]	[361,372]	5	hSpCas9	negative selection	1421952
47605320	47605343	X	-	26627737	RPE1	viability after 18 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.7454291206300425	[1221]	[344,774]	4	hSpCas9	negative selection	1421953
47606985	47607008	X	+	26627737	RPE1	viability after 18 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	-0.09071648871377791	[1594]	[351,459]	0	hSpCas9	negative selection	1421954
47619689	47619712	X	+	26627737	RPE1	viability after 18 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	-0.3749227051759116	[1234]	[271,240]	-2	hSpCas9	negative selection	1421955
47576154	47576177	X	-	26627737	HeLa	viability after 8 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.5472634656697795	[194]	[226,33,132]	5	hSpCas9	negative selection	1504265
47576328	47576351	X	-	26627737	HeLa	viability after 8 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.4711740448726238	[355]	[246,258,149]	4	hSpCas9	negative selection	1504266
47605034	47605057	X	-	26627737	HeLa	viability after 8 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.3958120651286453	[270]	[232,159,93]	3	hSpCas9	negative selection	1504267
47605320	47605343	X	-	26627737	HeLa	viability after 8 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	-0.8062875954491118	[499]	[259,46,97]	-7	hSpCas9	negative selection	1504268
47606985	47607008	X	+	26627737	HeLa	viability after 8 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.25624611325969293	[584]	[449,186,306]	2	hSpCas9	negative selection	1504269
47619689	47619712	X	+	26627737	HeLa	viability after 8 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.6190103979193619	[288]	[233,184,170]	5	hSpCas9	negative selection	1504270
47576154	47576177	X	-	26627737	HeLa	viability after 12 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.9825098980537048	[194]	[231,147,100]	7	hSpCas9	negative selection	1586580
47576328	47576351	X	-	26627737	HeLa	viability after 12 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-0.3503940685954958	[355]	[111,87,148]	-3	hSpCas9	negative selection	1586581
47605034	47605057	X	-	26627737	HeLa	viability after 12 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.20303045195703584	[270]	[145,102,140]	1	hSpCas9	negative selection	1586582
47605320	47605343	X	-	26627737	HeLa	viability after 12 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.38590789397793474	[499]	[365,135,324]	3	hSpCas9	negative selection	1586583
47606985	47607008	X	+	26627737	HeLa	viability after 12 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.7582254726266532	[584]	[475,339,419]	6	hSpCas9	negative selection	1586584
47619689	47619712	X	+	26627737	HeLa	viability after 12 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.7796069785802646	[288]	[284,189,143]	6	hSpCas9	negative selection	1586585
47576154	47576177	X	-	26627737	HeLa	viability after 15 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	1.3873754882982892	[194]	[243,92,291]	8	hSpCas9	negative selection	1668895
47576328	47576351	X	-	26627737	HeLa	viability after 15 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.19898575610127503	[355]	[206,131,158]	1	hSpCas9	negative selection	1668896
47605034	47605057	X	-	26627737	HeLa	viability after 15 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.23152671493599158	[270]	[100,169,116]	2	hSpCas9	negative selection	1668897
47605320	47605343	X	-	26627737	HeLa	viability after 15 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.008313537180998976	[499]	[138,162,321]	0	hSpCas9	negative selection	1668898
47606985	47607008	X	+	26627737	HeLa	viability after 15 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.8264030363156852	[584]	[180,461,643]	6	hSpCas9	negative selection	1668899
47619689	47619712	X	+	26627737	HeLa	viability after 15 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.588683013459843	[288]	[153,297,70]	5	hSpCas9	negative selection	1668900
47576154	47576177	X	-	26627737	HeLa	viability after 18 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	1.3740238712575628	[194]	[159,76,291]	8	hSpCas9	negative selection	1751210
47576328	47576351	X	-	26627737	HeLa	viability after 18 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.18945910893665752	[355]	[136,108,158]	1	hSpCas9	negative selection	1751211
47605034	47605057	X	-	26627737	HeLa	viability after 18 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.23164577103169554	[270]	[69,137,116]	2	hSpCas9	negative selection	1751212
47605320	47605343	X	-	26627737	HeLa	viability after 18 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	-0.015204417610818366	[499]	[81,140,321]	0	hSpCas9	negative selection	1751213
47606985	47607008	X	+	26627737	HeLa	viability after 18 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.844061913692841	[584]	[127,386,643]	6	hSpCas9	negative selection	1751214
47619689	47619712	X	+	26627737	HeLa	viability after 18 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.5455806535566597	[288]	[96,241,70]	4	hSpCas9	negative selection	1751215
47576154	47576177	X	-	26627737	HCT116	viability after 6 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	-1.3233394301732537	[328]	[10,25]	-6	hSpCas9	negative selection	1833525
47576328	47576351	X	-	26627737	HCT116	viability after 6 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.8381415984298689	[358]	[194,48]	4	hSpCas9	negative selection	1833526
47605034	47605057	X	-	26627737	HCT116	viability after 6 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	-0.37484205070456666	[450]	[122,16]	-2	hSpCas9	negative selection	1833527
47605320	47605343	X	-	26627737	HCT116	viability after 6 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.6132070841191415	[710]	[315,90]	3	hSpCas9	negative selection	1833528
47606985	47607008	X	+	26627737	HCT116	viability after 6 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.5284234082812369	[1248]	[502,161]	3	hSpCas9	negative selection	1833529
47619689	47619712	X	+	26627737	HCT116	viability after 6 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.0881808651606229	[676]	[87,126]	0	hSpCas9	negative selection	1833530
47576154	47576177	X	-	26627737	HCT116	viability after 8 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.24336717762859372	[121]	[68,44,123]	2	hSpCas9	negative selection	1915840
47576328	47576351	X	-	26627737	HCT116	viability after 8 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.06481629800185432	[259]	[170,134,143]	0	hSpCas9	negative selection	1915841
47605034	47605057	X	-	26627737	HCT116	viability after 8 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.07331695444785925	[288]	[152,149,198]	0	hSpCas9	negative selection	1915842
47605320	47605343	X	-	26627737	HCT116	viability after 8 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.2560720578970726	[393]	[216,295,263]	3	hSpCas9	negative selection	1915843
47606985	47607008	X	+	26627737	HCT116	viability after 8 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.10363088742112159	[613]	[342,365,380]	1	hSpCas9	negative selection	1915844
47619689	47619712	X	+	26627737	HCT116	viability after 8 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.7256496145521655	[181]	[269,114,114]	7	hSpCas9	negative selection	1915845
47576154	47576177	X	-	26627737	HCT116	viability after 9 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.6629218615995804	[328]	[142,135]	5	hSpCas9	negative selection	1998155
47576328	47576351	X	-	26627737	HCT116	viability after 9 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-0.22926624675949825	[358]	[102,64]	-1	hSpCas9	negative selection	1998156
47605034	47605057	X	-	26627737	HCT116	viability after 9 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	-1.2339726782006888	[450]	[96,14]	-7	hSpCas9	negative selection	1998157
47605320	47605343	X	-	26627737	HCT116	viability after 9 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.5931989727351854	[710]	[520,100]	4	hSpCas9	negative selection	1998158
47606985	47607008	X	+	26627737	HCT116	viability after 9 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.7402922114989521	[1248]	[760,395]	5	hSpCas9	negative selection	1998159
47619689	47619712	X	+	26627737	HCT116	viability after 9 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	-0.3170378882899405	[676]	[248,62]	-2	hSpCas9	negative selection	1998160
47576154	47576177	X	-	26627737	HCT116	viability after 12 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.9215332457710441	[121]	[97,146,121]	7	hSpCas9	negative selection	2080470
47576328	47576351	X	-	26627737	HCT116	viability after 12 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-0.3960813535557359	[259]	[90,77,142]	-4	hSpCas9	negative selection	2080471
47605034	47605057	X	-	26627737	HCT116	viability after 12 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	-0.1483935360170333	[288]	[124,171,115]	-1	hSpCas9	negative selection	2080472
47605320	47605343	X	-	26627737	HCT116	viability after 12 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.4224255832827039	[393]	[251,288,293]	4	hSpCas9	negative selection	2080473
47606985	47607008	X	+	26627737	HCT116	viability after 12 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.2553171765238027	[613]	[337,402,418]	2	hSpCas9	negative selection	2080474
47619689	47619712	X	+	26627737	HCT116	viability after 12 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	1.085968820142468	[181]	[177,148,282]	8	hSpCas9	negative selection	2080475
47576154	47576177	X	-	26627737	HCT116	viability after 15 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.6650525503522771	[121]	[137,123,74]	6	hSpCas9	negative selection	2162785
47576328	47576351	X	-	26627737	HCT116	viability after 15 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.2187998492591162	[259]	[190,124,206]	2	hSpCas9	negative selection	2162786
47605034	47605057	X	-	26627737	HCT116	viability after 15 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.1194858275302229	[288]	[258,153,137]	1	hSpCas9	negative selection	2162787
47605320	47605343	X	-	26627737	HCT116	viability after 15 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.4159394901917722	[393]	[476,233,216]	4	hSpCas9	negative selection	2162788
47606985	47607008	X	+	26627737	HCT116	viability after 15 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.18032675236993878	[613]	[389,529,278]	1	hSpCas9	negative selection	2162789
47619689	47619712	X	+	26627737	HCT116	viability after 15 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.5143654975587582	[181]	[193,82,175]	5	hSpCas9	negative selection	2162790
47576154	47576177	X	-	26627737	HCT116	viability after 18 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	1.507402417091654	[121]	[164,211,120]	9	hSpCas9	negative selection	2245100
47576328	47576351	X	-	26627737	HCT116	viability after 18 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.13434068254319803	[259]	[133,112,169]	1	hSpCas9	negative selection	2245101
47605034	47605057	X	-	26627737	HCT116	viability after 18 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.28271635403599826	[288]	[156,259,82]	2	hSpCas9	negative selection	2245102
47605320	47605343	X	-	26627737	HCT116	viability after 18 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.4907963900525462	[393]	[240,192,378]	4	hSpCas9	negative selection	2245103
47606985	47607008	X	+	26627737	HCT116	viability after 18 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.4432641987089758	[613]	[469,468,260]	4	hSpCas9	negative selection	2245104
47619689	47619712	X	+	26627737	HCT116	viability after 18 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.9046234727408986	[181]	[161,72,269]	7	hSpCas9	negative selection	2245105
47619561	47619584	X	-	24336569	HL60	viability	CCACTGCCGAGAGGTCCTCCGGG	SYN1	ENSG00000008056	0.6180427399880074	[475]	[1545]	5	hSpCas9	negative selection	2298576
47619570	47619593	X	-	24336569	HL60	viability	CCGGGACCGCCACTGCCGAGAGG	SYN1	ENSG00000008056	6.051935024788302	[4]	[701]	9	hSpCas9	negative selection	2298577
47619577	47619600	X	+	24336569	HL60	viability	GCAGTGGCGGTCCCGGGACCGGG	SYN1	ENSG00000008056	-1.5973022406952322	[325]	[227]	-8	hSpCas9	negative selection	2298578
47619655	47619678	X	+	24336569	HL60	viability	AGGTCTGTCATGTACCCATTTGG	SYN1	ENSG00000008056	-0.6817986149697908	[400]	[528]	-6	hSpCas9	negative selection	2298579
47619663	47619686	X	+	24336569	HL60	viability	CATGTACCCATTTGGCAGATTGG	SYN1	ENSG00000008056	0.5507279450207593	[610]	[1893]	5	hSpCas9	negative selection	2298580
47619669	47619692	X	-	24336569	HL60	viability	TTATGGCCAATCTGCCAAATGGG	SYN1	ENSG00000008056	-0.33069270693765984	[311]	[524]	-3	hSpCas9	negative selection	2298581
47619686	47619709	X	-	24336569	HL60	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	1.0998656640856654	[139]	[634]	8	hSpCas9	negative selection	2298582
47619701	47619724	X	-	24336569	HL60	viability	CTACCTGCGGCGCCGCCTGTCGG	SYN1	ENSG00000008056	0.5702542069187988	[365]	[1149]	5	hSpCas9	negative selection	2298583
47619708	47619731	X	+	24336569	HL60	viability	GCGGCGCCGCAGGTAGTTCATGG	SYN1	ENSG00000008056	0.46224106261442277	[200]	[585]	4	hSpCas9	negative selection	2298584
47619714	47619737	X	-	24336569	HL60	viability	TCGCAGCCATGAACTACCTGCGG	SYN1	ENSG00000008056	-0.02324948668360055	[424]	[884]	0	hSpCas9	negative selection	2298585
47619561	47619584	X	-	24336569	KBM7	viability	CCACTGCCGAGAGGTCCTCCGGG	SYN1	ENSG00000008056	0.5811797964325414	[297]	[1215]	5	hSpCas9	negative selection	2365753
47619570	47619593	X	-	24336569	KBM7	viability	CCGGGACCGCCACTGCCGAGAGG	SYN1	ENSG00000008056	7.216571755443689	[2]	[1216]	9	hSpCas9	negative selection	2365754
47619577	47619600	X	+	24336569	KBM7	viability	GCAGTGGCGGTCCCGGGACCGGG	SYN1	ENSG00000008056	-1.5215797779926596	[159]	[151]	-7	hSpCas9	negative selection	2365755
47619655	47619678	X	+	24336569	KBM7	viability	AGGTCTGTCATGTACCCATTTGG	SYN1	ENSG00000008056	0.35099581157810217	[258]	[900]	3	hSpCas9	negative selection	2365756
47619663	47619686	X	+	24336569	KBM7	viability	CATGTACCCATTTGGCAGATTGG	SYN1	ENSG00000008056	0.8876234758488084	[475]	[2401]	7	hSpCas9	negative selection	2365757
47619669	47619692	X	-	24336569	KBM7	viability	TTATGGCCAATCTGCCAAATGGG	SYN1	ENSG00000008056	1.0644709332578506	[185]	[1060]	8	hSpCas9	negative selection	2365758
47619686	47619709	X	-	24336569	KBM7	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	1.138485860619432	[217]	[1308]	8	hSpCas9	negative selection	2365759
47619701	47619724	X	-	24336569	KBM7	viability	CTACCTGCGGCGCCGCCTGTCGG	SYN1	ENSG00000008056	0.8081965633335526	[356]	[1704]	7	hSpCas9	negative selection	2365760
47619708	47619731	X	+	24336569	KBM7	viability	GCGGCGCCGCAGGTAGTTCATGG	SYN1	ENSG00000008056	0.5215471387921236	[306]	[1201]	5	hSpCas9	negative selection	2365761
47619714	47619737	X	-	24336569	KBM7	viability	TCGCAGCCATGAACTACCTGCGG	SYN1	ENSG00000008056	0.5282334836771742	[405]	[1596]	5	hSpCas9	negative selection	2365762
47582191	47582214	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAATAGTGACTGACGTGGAGG	SYN1	ENSG00000008056	0.8188121857484143	[146,74]	[35,49]	3	dCas9-VP64	positive selection	2432239
47582117	47582140	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATAGATTCTGGAGACTTTAGGGG	SYN1	ENSG00000008056	-0.6363071508969386	[129,119]	[20,12]	-3	dCas9-VP64	positive selection	2432240
47582138	47582161	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGACTGGGCCGGGGGAAATGCGG	SYN1	ENSG00000008056	1.6028936458204108	[0,9]	[3,3]	6	dCas9-VP64	positive selection	2432241
47580839	47580862	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCTCTTGAACCCCGG	SYN1	ENSG00000008056	0.7055876385115556	[3,484]	[1,182]	3	dCas9-VP64	positive selection	2452143
47582191	47582214	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAATAGTGACTGACGTGGAGG	SYN1	ENSG00000008056	-0.28852641723674977	[219,122]	[33,55]	-3	dCas9-VP64	positive selection	2527494
47582117	47582140	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATAGATTCTGGAGACTTTAGGGG	SYN1	ENSG00000008056	1.0299308165596117	[237,249]	[105,214]	6	dCas9-VP64	positive selection	2527495
47582138	47582161	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGACTGGGCCGGGGGAAATGCGG	SYN1	ENSG00000008056	-0.16789989031667507	[23,34]	[10,5]	-2	dCas9-VP64	positive selection	2527496
47580839	47580862	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCTCTTGAACCCCGG	SYN1	ENSG00000008056	-0.4319067453035411	[83,67]	[14,20]	-4	dCas9-VP64	positive selection	2547398
47577477	47577500	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	-0.23814749178095482	[3,2]	[0,3]	-3	hSpCas9	positive selection	3024888
47605292	47605315	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.3091929191240476	[2,3]	[3,2]	6	hSpCas9	positive selection	3024889
47577463	47577486	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCCCATCTTCACAACCACGGGG	SYN1	ENSG00000008056	-0.04031139751543061	[3,3]	[2,2]	0	hSpCas9	positive selection	3024890
47619458	47619481	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.08776784047051844	[2,2]	[3,1]	1	hSpCas9	positive selection	3024891
47577477	47577500	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.3293168677249316	[3,3]	[2,3]	6	hSpCas9	positive selection	3092746
47605292	47605315	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.27395766877879635	[2,2]	[3,1]	5	hSpCas9	positive selection	3092747
47577463	47577486	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCCCATCTTCACAACCACGGGG	SYN1	ENSG00000008056	-0.49132701076406105	[3,3]	[3,0]	-7	hSpCas9	positive selection	3092748
47619458	47619481	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.350246372036527	[2,2]	[3,2]	6	hSpCas9	positive selection	3092749
47619686	47619709		-	24336571	A375	resistance to PLX after 7 days	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.033053155494841	[24,20]	[21,24]	1	hSpCas9	positive selection	3148549
47619465	47619488		+	24336571	A375	resistance to PLX after 7 days	CGTGGTCTGCTTGACCGCGTTGG	SYN1	ENSG00000008056	0.15267373796373318	[21,21]	[23,24]	5	hSpCas9	positive selection	3148550
47607149	47607172		+	24336571	A375	resistance to PLX after 7 days	CTTTAATGTCAATTTCTCCATGG	SYN1	ENSG00000008056	0.3972347861226497	[10,13]	[16,16]	8	hSpCas9	positive selection	3148551
47607181	47607204		-	24336571	A375	resistance to PLX after 7 days	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.20588891842414642	[15,12]	[15,16]	6	hSpCas9	positive selection	3148552
47619686	47619709		-	24336571	A375	resistance to PLX after 14 days	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	-0.613152463965974	[30,22]	[8,6]	-7	hSpCas9	positive selection	3206342
47619465	47619488		+	24336571	A375	resistance to PLX after 14 days	CGTGGTCTGCTTGACCGCGTTGG	SYN1	ENSG00000008056	0.15178520684977836	[24,16]	[9,10]	1	hSpCas9	positive selection	3206343
47607149	47607172		+	24336571	A375	resistance to PLX after 14 days	CTTTAATGTCAATTTCTCCATGG	SYN1	ENSG00000008056	-0.5909175804112313	[15,13]	[3,4]	-7	hSpCas9	positive selection	3206344
47607181	47607204		-	24336571	A375	resistance to PLX after 14 days	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.13828061062716512	[14,19]	[6,10]	1	hSpCas9	positive selection	3206345
47619686	47619709		-	24336571	A375	viability after 7 days	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.6458886004618954	[14]	[24,20]	8	hSpCas9	negative selection	3264135
47619465	47619488		+	24336571	A375	viability after 7 days	CGTGGTCTGCTTGACCGCGTTGG	SYN1	ENSG00000008056	0.5454090969588112	[15]	[21,21]	7	hSpCas9	negative selection	3264136
47607149	47607172		+	24336571	A375	viability after 7 days	CTTTAATGTCAATTTCTCCATGG	SYN1	ENSG00000008056	-1.2595572843012859	[31]	[10,13]	-9	hSpCas9	negative selection	3264137
47607181	47607204		-	24336571	A375	viability after 7 days	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.4023818833703387	[10]	[15,12]	6	hSpCas9	negative selection	3264138
47619686	47619709		-	24336571	A375	viability after 14 days	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.9001914015739177	[14]	[30,22]	9	hSpCas9	negative selection	3321928
47619465	47619488		+	24336571	A375	viability after 14 days	CGTGGTCTGCTTGACCGCGTTGG	SYN1	ENSG00000008056	0.4879976034879254	[15]	[24,16]	6	hSpCas9	negative selection	3321929
47607149	47607172		+	24336571	A375	viability after 14 days	CTTTAATGTCAATTTCTCCATGG	SYN1	ENSG00000008056	-0.9630046464366174	[31]	[15,13]	-8	hSpCas9	negative selection	3321930
47607181	47607204		-	24336571	A375	viability after 14 days	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.7311635326644741	[10]	[14,19]	8	hSpCas9	negative selection	3321931
47606980	47607003	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.47059424311736403	[211,211]	[0,0]	-3	hSpCas9	positive selection	3395833
47607181	47607204	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	2.3031299010589596	[30,30]	[0,0]	8	hSpCas9	positive selection	3395834
47607140	47607163	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	0.21293209208738176	[131,131]	[0,0]	1	hSpCas9	positive selection	3395835
47577477	47577500	X	-	26780180	HT29	viability (Avana library 4 designs)	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.220368269418575	[]	[]	0	hSpCas9	negative selection	3463597
47605291	47605314	X	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.357592449967925	[]	[]	1	hSpCas9	negative selection	3463598
47577462	47577485	X	+	26780180	HT29	viability (Avana library 4 designs)	GCCCCATCTTCACAACCACGGGG	SYN1	ENSG00000008056	0.038239815188664	[]	[]	0	hSpCas9	negative selection	3463599
47619458	47619481	X	-	26780180	HT29	viability (Avana library 4 designs)	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	1.62320617063642	[]	[]	6	hSpCas9	negative selection	3463600
47577462	47577485	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCCATCTTCACAACCACGGGG	SYN1	ENSG00000008056	-2.83237812151025	[]	[]	-3	hSpCas9	negative selection	3565713
47619458	47619481	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	4.88094396558888	[]	[]	8	hSpCas9	negative selection	3565714
47605291	47605314	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	1.50909041366241	[]	[]	2	hSpCas9	negative selection	3565715
47577477	47577500	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	3.82778069402466	[]	[]	6	hSpCas9	negative selection	3565716
47604998	47605021	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGGTCTGATCAATTAGAGGG	SYN1	ENSG00000008056	-4.62300212367919	[]	[]	-5	hSpCas9	negative selection	3565717
47576545	47576568	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGGCATCGATGAAGGGCTCGG	SYN1	ENSG00000008056	3.75386429546583	[]	[]	6	hSpCas9	negative selection	3565718
47577462	47577485	X	+	26780180	A375	viability (Avana lentiGuide)	GCCCCATCTTCACAACCACGGGG	SYN1	ENSG00000008056	-8.15769910068737	[]	[]	-9	hSpCas9	negative selection	3674372
47619458	47619481	X	-	26780180	A375	viability (Avana lentiGuide)	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	1.26780381604433	[]	[]	1	hSpCas9	negative selection	3674373
47605291	47605314	X	+	26780180	A375	viability (Avana lentiGuide)	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	1.23959768122989	[]	[]	1	hSpCas9	negative selection	3674374
47577477	47577500	X	-	26780180	A375	viability (Avana lentiGuide)	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	-2.49509684007858	[]	[]	-4	hSpCas9	negative selection	3674375
47604998	47605021	X	+	26780180	A375	viability (Avana lentiGuide)	AGAAGGTCTGATCAATTAGAGGG	SYN1	ENSG00000008056	-2.15093336636644	[]	[]	-4	hSpCas9	negative selection	3674376
47576545	47576568	X	+	26780180	A375	viability (Avana lentiGuide)	TTTGGCATCGATGAAGGGCTCGG	SYN1	ENSG00000008056	-0.422061739902847	[]	[]	0	hSpCas9	negative selection	3674377
47577462	47577485	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCCATCTTCACAACCACGGGG	SYN1	ENSG00000008056	-0.17872347347505668	[3]	[2,3]	-3	hSpCas9	positive selection	3782979
47619458	47619481	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.16308399358173686	[4]	[4,4]	4	hSpCas9	positive selection	3782980
47605291	47605314	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.18312305715912003	[3]	[3,4]	5	hSpCas9	positive selection	3782981
47577477	47577500	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.25436664071546833	[4]	[5,5]	7	hSpCas9	positive selection	3782982
47604998	47605021	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGGTCTGATCAATTAGAGGG	SYN1	ENSG00000008056	-0.5626665644347266	[8]	[5,5]	-7	hSpCas9	positive selection	3782983
47576545	47576568	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGGCATCGATGAAGGGCTCGG	SYN1	ENSG00000008056	0.04499483644847928	[5]	[6,3]	1	hSpCas9	positive selection	3782984
47577462	47577485	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCCATCTTCACAACCACGGGG	SYN1	ENSG00000008056	0.09269498477606086	[5]	[4,4]	2	hSpCas9	positive selection	3891586
47619458	47619481	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	-0.008442962257423803	[4]	[5,2]	0	hSpCas9	positive selection	3891587
47605291	47605314	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.09029787136708473	[5]	[4,3]	2	hSpCas9	positive selection	3891588
47577477	47577500	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.7953880114986269	[5]	[4,10]	9	hSpCas9	positive selection	3891589
47604998	47605021	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGGTCTGATCAATTAGAGGG	SYN1	ENSG00000008056	0.3897782078810785	[5]	[5,6]	9	hSpCas9	positive selection	3891590
47576545	47576568	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGGCATCGATGAAGGGCTCGG	SYN1	ENSG00000008056	0.21161100521119808	[5]	[5,4]	5	hSpCas9	positive selection	3891591
47607140	47607163	X	-	26780180	A375	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	1.37411149989771	[]	[]	7	hSpCas9	negative selection	4001243
47606959	47606982	X	-	26780180	A375	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.581825508239116	[]	[]	1	hSpCas9	negative selection	4001244
47606980	47607003	X	+	26780180	A375	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	1.06999009261074	[]	[]	5	hSpCas9	negative selection	4001245
47619686	47619709	X	+	26780180	A375	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.521138179323934	[]	[]	1	hSpCas9	negative selection	4001246
47619686	47619709	X	-	26780180	A375	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.400554656445174	[]	[]	1	hSpCas9	negative selection	4001247
47607181	47607204	X	-	26780180	A375	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.839446812546493	[]	[]	3	hSpCas9	negative selection	4001248
47607140	47607163	X	-	26780180	HT29	viability (GeCKOv2 library)	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	2.10175048391377	[]	[]	9	hSpCas9	negative selection	4109209
47606959	47606982	X	-	26780180	HT29	viability (GeCKOv2 library)	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	1.52267143335756	[]	[]	7	hSpCas9	negative selection	4109210
47606980	47607003	X	+	26780180	HT29	viability (GeCKOv2 library)	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	1.21246840833264	[]	[]	6	hSpCas9	negative selection	4109211
47619686	47619709	X	+	26780180	HT29	viability (GeCKOv2 library)	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	1.37374147185158	[]	[]	7	hSpCas9	negative selection	4109212
47619686	47619709	X	-	26780180	HT29	viability (GeCKOv2 library)	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	-0.622884830064806	[]	[]	-9	hSpCas9	negative selection	4109213
47607181	47607204	X	-	26780180	HT29	viability (GeCKOv2 library)	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	1.33134789171713	[]	[]	6	hSpCas9	negative selection	4109214
47619686	47619709	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.10558849132978554	[4]	[3,2]	2	hSpCas9	positive selection	4174811
47619465	47619488	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTGGTCTGCTTGACCGCGTTGG	SYN1	ENSG00000008056	0.6536468697491408	[4]	[6,3]	9	hSpCas9	positive selection	4174812
47607149	47607172	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTTAATGTCAATTTCTCCATGG	SYN1	ENSG00000008056	-0.05242957811272391	[3]	[2,1]	-1	hSpCas9	positive selection	4174813
47607181	47607204	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.22262936662890953	[3]	[2,3]	5	hSpCas9	positive selection	4174814
47584934	47584957	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.1815601154156128	[4]	[3,3]	4	hSpCas9	positive selection	4176752
47585262	47585285	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCGCCATGGAGAGTGTCTGCGG	SYN1	ENSG00000008056	0.5256291864446861	[2]	[2,2]	9	hSpCas9	positive selection	4176753
47585236	47585259	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.26048881786542954	[3]	[2,3]	6	hSpCas9	positive selection	4176754
47584988	47585011	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.23309184787203097	[3]	[1,2]	-5	hSpCas9	positive selection	4176755
47619686	47619709	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	1.0459051179144139	[4]	[1,4,1,5]	7	hSpCas9	positive selection	4238833
47619465	47619488	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTGGTCTGCTTGACCGCGTTGG	SYN1	ENSG00000008056	0.8243329817743937	[3]	[0,2,3,3]	5	hSpCas9	positive selection	4238834
47607149	47607172	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTTAATGTCAATTTCTCCATGG	SYN1	ENSG00000008056	0.6295290550587708	[4]	[6,2,5,0]	4	hSpCas9	positive selection	4238835
47607181	47607204	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	1.1506041362192858	[3]	[1,3,4,3]	8	hSpCas9	positive selection	4238836
47584934	47584957	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.24364255953210046	[3]	[4,2,2,0]	2	hSpCas9	positive selection	4240774
47585262	47585285	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCGCCATGGAGAGTGTCTGCGG	SYN1	ENSG00000008056	0.12174538312501856	[3]	[2,2,1,0]	1	hSpCas9	positive selection	4240775
47585236	47585259	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.23485989627981174	[2]	[1,0,0,0]	-3	hSpCas9	positive selection	4240776
47584988	47585011	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	0.531117597020415	[4]	[5,3,3,0]	3	hSpCas9	positive selection	4240777
47619686	47619709	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.3826896687036967	[3]	[4,2]	7	hSpCas9	positive selection	4301579
47619686	47619709	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.11067358466635963	[3]	[3,2]	2	hSpCas9	positive selection	4301580
47606959	47606982	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.5435495475013487	[2]	[3,2]	9	hSpCas9	positive selection	4301581
47584988	47585011	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.33830449941911034	[3]	[2,1]	-6	hSpCas9	positive selection	4303156
47585236	47585259	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.3628918518378901	[0]	[0,0]	7	hSpCas9	positive selection	4303157
47584934	47584957	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.2135283095812422	[2]	[3,1]	4	hSpCas9	positive selection	4303158
47606980	47607003	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.09362772575425099	[3]	[3,1]	-2	hSpCas9	positive selection	4365832
47607181	47607204	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.08414030696944441	[1]	[1,0]	-2	hSpCas9	positive selection	4365833
47607140	47607163	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.22430041596274974	[3]	[3,0]	-4	hSpCas9	positive selection	4365834
47585294	47585317	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.10681625951973589	[2]	[1,0]	-2	hSpCas9	positive selection	4367409
47585629	47585652	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.6564794001707193	[2]	[1,0]	-9	hSpCas9	positive selection	4367410
47585603	47585626	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.006789025556285855	[2]	[2,1]	0	hSpCas9	positive selection	4367411
47606959	47606981	X	-	27760321	OCIAML3	viability	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	1.3599839077483005	[158,114]	[270,273]	9	hSpCas9	negative selection	4444664
47619560	47619582	X	-	27760321	OCIAML3	viability	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	0.48830803424829505	[799,609]	[664,900]	6	hSpCas9	negative selection	4444665
47576540	47576562	X	+	27760321	OCIAML3	viability	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	-0.4063772994116883	[246,255]	[83,233]	-4	hSpCas9	negative selection	4444666
47605041	47605063	X	+	27760321	OCIAML3	viability	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	0.34947119943761834	[527,500]	[425,626]	4	hSpCas9	negative selection	4444667
47605320	47605342	X	-	27760321	OCIAML3	viability	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.2616645368291146	[656,556]	[442,728]	3	hSpCas9	negative selection	4444668
47606959	47606981	X	-	27760321	OCIAML2	viability	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.10532349814725173	[158,114]	[111,125]	1	hSpCas9	negative selection	4528127
47619560	47619582	X	-	27760321	OCIAML2	viability	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	0.4644424833437064	[799,609]	[643,960]	6	hSpCas9	negative selection	4528128
47576540	47576562	X	+	27760321	OCIAML2	viability	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	0.16338496901660526	[246,255]	[196,270]	2	hSpCas9	negative selection	4528129
47605041	47605063	X	+	27760321	OCIAML2	viability	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	0.5883637761523071	[527,500]	[553,721]	7	hSpCas9	negative selection	4528130
47605320	47605342	X	-	27760321	OCIAML2	viability	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.5058007926329993	[656,556]	[576,849]	7	hSpCas9	negative selection	4528131
47606959	47606981	X	-	27760321	MV411	viability	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	-2.6170571462627867	[158,114]	[2,31]	-9	hSpCas9	negative selection	4611590
47619560	47619582	X	-	27760321	MV411	viability	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	0.9831532338006541	[799,609]	[557,1444]	7	hSpCas9	negative selection	4611591
47576540	47576562	X	+	27760321	MV411	viability	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	-0.8971327219431056	[246,255]	[15,199]	-6	hSpCas9	negative selection	4611592
47605041	47605063	X	+	27760321	MV411	viability	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	0.22821737718934532	[527,500]	[105,836]	1	hSpCas9	negative selection	4611593
47605320	47605342	X	-	27760321	MV411	viability	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	1.6616278311327952	[656,556]	[1090,1520]	9	hSpCas9	negative selection	4611594
47606959	47606981	X	-	27760321	HL60	viability	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.8220050600432909	[158,114]	[158,234]	8	hSpCas9	negative selection	4695053
47619560	47619582	X	-	27760321	HL60	viability	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	0.8087530700117069	[799,609]	[1015,984]	8	hSpCas9	negative selection	4695054
47576540	47576562	X	+	27760321	HL60	viability	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	0.5667175361671501	[246,255]	[263,349]	6	hSpCas9	negative selection	4695055
47605041	47605063	X	+	27760321	HL60	viability	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	0.6750018730280114	[527,500]	[531,819]	7	hSpCas9	negative selection	4695056
47605320	47605342	X	-	27760321	HL60	viability	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.5437466549742277	[656,556]	[630,814]	6	hSpCas9	negative selection	4695057
47606959	47606981	X	-	27760321	HT1080	viability	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	2.202680686550674	[114,89]	[50,337]	9	hSpCas9	negative selection	4778516
47619560	47619582	X	-	27760321	HT1080	viability	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	1.2132152784657322	[609,475]	[596,396]	6	hSpCas9	negative selection	4778517
47576540	47576562	X	+	27760321	HT1080	viability	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	-0.028130989411678464	[255,199]	[153,17]	0	hSpCas9	negative selection	4778518
47605041	47605063	X	+	27760321	HT1080	viability	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	1.1036775009479052	[500,390]	[356,408]	6	hSpCas9	negative selection	4778519
47605320	47605342	X	-	27760321	HT1080	viability	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	-0.7074077219896538	[556,434]	[173,62]	-3	hSpCas9	negative selection	4778520
47606959	47606981	X	-	27760321	HT29	viability after 7 days	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	-0.7175258332943162	[114,89]	[61,102,72]	-7	hSpCas9	negative selection	4861979
47619560	47619582	X	-	27760321	HT29	viability after 7 days	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	0.2583817622164134	[609,475]	[920,720,872]	4	hSpCas9	negative selection	4861980
47576540	47576562	X	+	27760321	HT29	viability after 7 days	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	-0.07600591620149066	[255,199]	[177,87,544]	-1	hSpCas9	negative selection	4861981
47605041	47605063	X	+	27760321	HT29	viability after 7 days	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	-0.42220115257865687	[500,390]	[422,542,319]	-6	hSpCas9	negative selection	4861982
47605320	47605342	X	-	27760321	HT29	viability after 7 days	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.2663870983410083	[556,434]	[658,836,787]	4	hSpCas9	negative selection	4861983
47606959	47606981	X	-	27760321	HT29	viability after 25 days	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	-0.284798919838112	[114,89]	[63,124,101]	-3	hSpCas9	negative selection	4945442
47619560	47619582	X	-	27760321	HT29	viability after 25 days	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	0.2715962234583199	[609,475]	[623,768,873]	3	hSpCas9	negative selection	4945443
47576540	47576562	X	+	27760321	HT29	viability after 25 days	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	-0.3841792980108023	[255,199]	[140,195,272]	-4	hSpCas9	negative selection	4945444
47605041	47605063	X	+	27760321	HT29	viability after 25 days	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	0.005593921028716253	[500,390]	[376,513,667]	0	hSpCas9	negative selection	4945445
47605320	47605342	X	-	27760321	HT29	viability after 25 days	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.005232807822634689	[556,434]	[543,658,496]	0	hSpCas9	negative selection	4945446
47606959	47606981	X	-	27760321	HT29	viability after 22 days	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.025967050130584424	[114,89]	[149,111,98]	0	hSpCas9	negative selection	5028905
47619560	47619582	X	-	27760321	HT29	viability after 22 days	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	0.13345621128943075	[609,475]	[553,858,655]	1	hSpCas9	negative selection	5028906
47576540	47576562	X	+	27760321	HT29	viability after 22 days	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	-0.6434083100552836	[255,199]	[95,161,250]	-5	hSpCas9	negative selection	5028907
47605041	47605063	X	+	27760321	HT29	viability after 22 days	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	0.08429724729489524	[500,390]	[633,506,495]	0	hSpCas9	negative selection	5028908
47605320	47605342	X	-	27760321	HT29	viability after 22 days	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.3491648640046661	[556,434]	[951,638,592]	3	hSpCas9	negative selection	5028909
47606959	47606981	X	-	27760321	HT29	viability after 19 days	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	-0.008710067300131907	[114,89]	[106,163,78]	0	hSpCas9	negative selection	5112368
47619560	47619582	X	-	27760321	HT29	viability after 19 days	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	0.4494720794307394	[609,475]	[800,874,861]	4	hSpCas9	negative selection	5112369
47576540	47576562	X	+	27760321	HT29	viability after 19 days	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	-0.4407908118125179	[255,199]	[269,111,201]	-4	hSpCas9	negative selection	5112370
47605041	47605063	X	+	27760321	HT29	viability after 19 days	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	0.08144705317110529	[500,390]	[447,697,465]	0	hSpCas9	negative selection	5112371
47605320	47605342	X	-	27760321	HT29	viability after 19 days	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.4587877543371968	[556,434]	[1298,505,594]	4	hSpCas9	negative selection	5112372
47606959	47606981	X	-	27760321	HT29	viability after 16 days	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	-0.6701521752608135	[114,89]	[84,50,81]	-6	hSpCas9	negative selection	5195831
47619560	47619582	X	-	27760321	HT29	viability after 16 days	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	0.5070128111432359	[609,475]	[782,987,807]	6	hSpCas9	negative selection	5195832
47576540	47576562	X	+	27760321	HT29	viability after 16 days	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	0.3279595768853186	[255,199]	[292,435,225]	3	hSpCas9	negative selection	5195833
47605041	47605063	X	+	27760321	HT29	viability after 16 days	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	0.09821624614647961	[500,390]	[619,665,320]	1	hSpCas9	negative selection	5195834
47605320	47605342	X	-	27760321	HT29	viability after 16 days	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.4208858698853574	[556,434]	[1094,587,582]	5	hSpCas9	negative selection	5195835
47606959	47606981	X	-	27760321	HT29	viability after 13 days	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	-0.7300160032094734	[114,89]	[75,99,40]	-6	hSpCas9	negative selection	5279294
47619560	47619582	X	-	27760321	HT29	viability after 13 days	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	0.23873270681138914	[609,475]	[689,781,756]	3	hSpCas9	negative selection	5279295
47576540	47576562	X	+	27760321	HT29	viability after 13 days	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	-0.483458013083202	[255,199]	[171,178,214]	-5	hSpCas9	negative selection	5279296
47605041	47605063	X	+	27760321	HT29	viability after 13 days	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	-0.6369465236192794	[500,390]	[271,405,320]	-6	hSpCas9	negative selection	5279297
47605320	47605342	X	-	27760321	HT29	viability after 13 days	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.30927948601191585	[556,434]	[626,728,778]	4	hSpCas9	negative selection	5279298
47606959	47606981	X	-	27760321	HT29	viability after 10 days	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.2856690797810293	[114,89]	[97,240,131]	4	hSpCas9	negative selection	5362757
47619560	47619582	X	-	27760321	HT29	viability after 10 days	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	0.4124287628104166	[609,475]	[742,1017,947]	5	hSpCas9	negative selection	5362758
47576540	47576562	X	+	27760321	HT29	viability after 10 days	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	-0.19374237440073672	[255,199]	[212,250,281]	-3	hSpCas9	negative selection	5362759
47605041	47605063	X	+	27760321	HT29	viability after 10 days	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	-0.3674543884670756	[500,390]	[468,577,255]	-5	hSpCas9	negative selection	5362760
47605320	47605342	X	-	27760321	HT29	viability after 10 days	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.5138865432825741	[556,434]	[1144,631,868]	7	hSpCas9	negative selection	5362761
47606959	47606981	X	-	27760321	MOLM13	viability	TATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.3925290354796984	[158,114]	[100,99]	2	hSpCas9	negative selection	5446220
47619560	47619582	X	-	27760321	MOLM13	viability	ACTGCCGAGAGGTCCTCCGGGG	SYN1	ENSG00000008056	1.1228132796849382	[799,609]	[442,1213]	7	hSpCas9	negative selection	5446221
47576540	47576562	X	+	27760321	MOLM13	viability	TCATATTTGGCATCGATGAAGG	SYN1	ENSG00000008056	0.33930772210008486	[246,255]	[208,155]	2	hSpCas9	negative selection	5446222
47605041	47605063	X	+	27760321	MOLM13	viability	CTTATGCAGTCGAACCATCTGG	SYN1	ENSG00000008056	-0.2731487763156608	[527,500]	[307,182]	-2	hSpCas9	negative selection	5446223
47605320	47605342	X	-	27760321	MOLM13	viability	CCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	1.123720938614123	[656,556]	[922,590]	7	hSpCas9	negative selection	5446224
47619426	47619449	X	+	27661255	K562	viability	GCCGCCCACCTGCTCGCTGAAGG	SYN1	ENSG00000008056	-0.2941386989017256	[145,157]	[113,85]	-7	dCas9-KRAB	negative selection	5515443
47619555	47619578	X	+	27661255	K562	viability	GGCGACCCCGGAGGACCTCTCGG	SYN1	ENSG00000008056	-0.005190080310236267	[340,393]	[301,282]	0	dCas9-KRAB	negative selection	5515444
47619430	47619453	X	-	27661255	K562	viability	GCCACCTTCAGCGAGCAGGTGGG	SYN1	ENSG00000008056	-0.10389595064259816	[419,556]	[377,346]	-4	dCas9-KRAB	negative selection	5515445
47619845	47619868	X	-	27661255	K562	viability	GCGCTGCCTCAGTCTGCGGTGGG	SYN1	ENSG00000008056	0.41934282275178025	[504,511]	[575,514]	9	dCas9-KRAB	negative selection	5515446
47585275	47585298	X	+	27661255	K562	viability	GTGTCTGCGGATACTTCCACAGG	SYN1	ENSG00000008056	0.34867488430925103	[696,772]	[857,650]	9	dCas9-KRAB	negative selection	5517387
47585709	47585732	X	+	27661255	K562	viability	GGGGCCATTCCCTAAATCGTGGG	SYN1	ENSG00000008056	0.17954820424793017	[1848,1778]	[1909,1413]	6	dCas9-KRAB	negative selection	5517388
47582669	47582692	X	-	27661255	K562	viability	GGCGGATGTCAGGGGTTCTAGGG	SYN1	ENSG00000008056	-0.004686684545274045	[896,975]	[838,663]	0	dCas9-KRAB	negative selection	5517389
47582923	47582946	X	-	27661255	K562	viability	GGGGAGTTTGGAGGTTGAAGGGG	SYN1	ENSG00000008056	-0.06799067253196765	[826,738]	[700,509]	-3	dCas9-KRAB	negative selection	5517390
47585236	47585259	X	-	27661255	K562	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.12895169771731568	[998,962]	[918,804]	4	dCas9-KRAB	negative selection	5517391
47585358	47585381	X	-	27661255	K562	viability	GCCCCAGGGACTGGTTGGTGTGG	SYN1	ENSG00000008056	0.07572327151749514	[314,402]	[369,241]	2	dCas9-KRAB	negative selection	5517392
47619686	47619709	X	-	27260156	BXPC3	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.6564473170766483	[547]	[878,793,840,1127]	9	hSpCas9	negative selection	5574039
47619686	47619709	X	+	27260156	BXPC3	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.0907865950215484	[638]	[689,581,836,748]	2	hSpCas9	negative selection	5574040
47606959	47606982	X	-	27260156	BXPC3	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.561110918970557	[393]	[616,625,598,578]	9	hSpCas9	negative selection	5574041
47584988	47585011	X	-	27260156	BXPC3	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.2530611396555861	[813]	[568,594,925,798]	-5	hSpCas9	negative selection	5575616
47585236	47585259	X	-	27260156	BXPC3	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.06171780769732926	[0]	[0,0,0,0]	-1	hSpCas9	negative selection	5575617
47584934	47584957	X	+	27260156	BXPC3	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.3806696981226305	[410]	[518,555,599,564]	7	hSpCas9	negative selection	5575618
47606980	47607003	X	+	27260156	BXPC3	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.02616391494053938	[685]	[594,546,844,869]	0	hSpCas9	negative selection	5638292
47607181	47607204	X	-	27260156	BXPC3	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.12474140617932994	[161]	[146,205,215,169]	2	hSpCas9	negative selection	5638293
47607140	47607163	X	-	27260156	BXPC3	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.283995671437132	[504]	[306,394,516,543]	-6	hSpCas9	negative selection	5638294
47585294	47585317	X	+	27260156	BXPC3	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.440472749938986	[221]	[242,148,122,158]	-7	hSpCas9	negative selection	5639869
47585629	47585652	X	+	27260156	BXPC3	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	0.46953285648580334	[220]	[300,231,350,412]	8	hSpCas9	negative selection	5639870
47585603	47585626	X	+	27260156	BXPC3	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.08027733908574763	[259]	[234,326,220,377]	1	hSpCas9	negative selection	5639871
47619686	47619709	X	-	27260156	A673	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.5817394190561432	[547]	[1039,917,785,1215]	9	hSpCas9	negative selection	5695290
47619686	47619709	X	+	27260156	A673	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.020608286851854174	[638]	[808,618,884,806]	0	hSpCas9	negative selection	5695291
47606959	47606982	X	-	27260156	A673	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.36278627317669876	[393]	[779,506,516,653]	8	hSpCas9	negative selection	5695292
47584988	47585011	X	-	27260156	A673	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.047082975448911935	[813]	[1040,734,979,1047]	-1	hSpCas9	negative selection	5696867
47585236	47585259	X	-	27260156	A673	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.2631622979798074	[0]	[0,0,0,0]	-6	hSpCas9	negative selection	5696868
47584934	47584957	X	+	27260156	A673	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.47133587110491615	[410]	[832,623,755,531]	9	hSpCas9	negative selection	5696869
47606980	47607003	X	+	27260156	A673	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.05428271656203232	[685]	[828,823,866,645]	-1	hSpCas9	negative selection	5759543
47607181	47607204	X	-	27260156	A673	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.06790062792320395	[161]	[256,103,221,167]	-2	hSpCas9	negative selection	5759544
47607140	47607163	X	-	27260156	A673	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.6090105682607496	[504]	[409,333,436,411]	-9	hSpCas9	negative selection	5759545
47585294	47585317	X	+	27260156	A673	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.15760060136497112	[221]	[309,220,230,199]	-4	hSpCas9	negative selection	5761120
47585629	47585652	X	+	27260156	A673	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.30441576656580627	[220]	[242,204,195,218]	-6	hSpCas9	negative selection	5761121
47585603	47585626	X	+	27260156	A673	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.07938074201979417	[259]	[300,331,295,389]	2	hSpCas9	negative selection	5761122
47619686	47619709	X	-	27260156	A375	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.7980891906699669	[547]	[1233,1281,1075,904]	9	hSpCas9	negative selection	5816541
47619686	47619709	X	+	27260156	A375	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	-0.0208694778975283	[638]	[636,817,857,647]	0	hSpCas9	negative selection	5816542
47606959	47606982	X	-	27260156	A375	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.6708142402067795	[393]	[695,1165,701,456]	8	hSpCas9	negative selection	5816543
47584988	47585011	X	-	27260156	A375	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.2909308186484747	[813]	[598,938,814,773]	-4	hSpCas9	negative selection	5818118
47585236	47585259	X	-	27260156	A375	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.22260698094002684	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	5818119
47584934	47584957	X	+	27260156	A375	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.34472437266685796	[410]	[565,824,624,466]	5	hSpCas9	negative selection	5818120
47606980	47607003	X	+	27260156	A375	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.089428743905002	[685]	[912,934,851,732]	1	hSpCas9	negative selection	5880794
47607181	47607204	X	-	27260156	A375	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.4079748661168008	[161]	[135,402,357,139]	6	hSpCas9	negative selection	5880795
47607140	47607163	X	-	27260156	A375	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	0.04473232936862877	[504]	[491,575,657,689]	0	hSpCas9	negative selection	5880796
47585294	47585317	X	+	27260156	A375	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.10439954409007579	[221]	[285,389,262,199]	1	hSpCas9	negative selection	5882371
47585629	47585652	X	+	27260156	A375	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.6200988676899304	[220]	[152,234,185,112]	-7	hSpCas9	negative selection	5882372
47585603	47585626	X	+	27260156	A375	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.5680172930753133	[259]	[573,563,312,373]	8	hSpCas9	negative selection	5882373
47619686	47619709	X	-	27260156	COLO741	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.48805797725143685	[547]	[1058,932,959]	8	hSpCas9	negative selection	5937792
47619686	47619709	X	+	27260156	COLO741	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.1543625876601562	[638]	[911,1039,781]	3	hSpCas9	negative selection	5937793
47606959	47606982	X	-	27260156	COLO741	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.518841093292521	[393]	[644,831,681]	9	hSpCas9	negative selection	5937794
47584988	47585011	X	-	27260156	COLO741	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.19730190019873206	[813]	[917,1142,676]	-4	hSpCas9	negative selection	5939369
47585236	47585259	X	-	27260156	COLO741	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.3524737808476335	[0]	[0,0,0]	-6	hSpCas9	negative selection	5939370
47584934	47584957	X	+	27260156	COLO741	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.2873649857752567	[410]	[539,705,664]	6	hSpCas9	negative selection	5939371
47606980	47607003	X	+	27260156	COLO741	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.11942808969233143	[685]	[1004,877,973]	2	hSpCas9	negative selection	6002045
47607181	47607204	X	-	27260156	COLO741	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.27220353903160466	[161]	[165,156,188]	-5	hSpCas9	negative selection	6002046
47607140	47607163	X	-	27260156	COLO741	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.5437634921631076	[504]	[506,546,289]	-8	hSpCas9	negative selection	6002047
47585294	47585317	X	+	27260156	COLO741	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.11089220365789376	[221]	[406,246,274]	2	hSpCas9	negative selection	6003622
47585629	47585652	X	+	27260156	COLO741	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.16494661511890518	[220]	[309,241,210]	-4	hSpCas9	negative selection	6003623
47585603	47585626	X	+	27260156	COLO741	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.22410295613937858	[259]	[506,318,349]	5	hSpCas9	negative selection	6003624
47619686	47619709	X	-	27260156	CAL120	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.9473585942225397	[547]	[1586,1232,1167]	9	hSpCas9	negative selection	6059043
47619686	47619709	X	+	27260156	CAL120	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.2922743896080682	[638]	[845,881,1169]	4	hSpCas9	negative selection	6059044
47606959	47606982	X	-	27260156	CAL120	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.8431351142572943	[393]	[1220,719,750]	9	hSpCas9	negative selection	6059045
47584988	47585011	X	-	27260156	CAL120	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.48573400351581975	[813]	[721,578,865]	-6	hSpCas9	negative selection	6060620
47585236	47585259	X	-	27260156	CAL120	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.31522623407729533	[0]	[0,0,0]	-4	hSpCas9	negative selection	6060621
47584934	47584957	X	+	27260156	CAL120	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.636973708140472	[410]	[996,679,739]	8	hSpCas9	negative selection	6060622
47606980	47607003	X	+	27260156	CAL120	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.13084560569216186	[685]	[1415,966,500]	2	hSpCas9	negative selection	6123296
47607181	47607204	X	-	27260156	CAL120	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.8253085602509337	[161]	[455,366,264]	9	hSpCas9	negative selection	6123297
47607140	47607163	X	-	27260156	CAL120	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.030726851385590698	[504]	[631,667,548]	0	hSpCas9	negative selection	6123298
47585294	47585317	X	+	27260156	CAL120	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.467552134397073	[221]	[386,127,113]	-6	hSpCas9	negative selection	6124873
47585629	47585652	X	+	27260156	CAL120	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.584540496386496	[220]	[113,316,109]	-7	hSpCas9	negative selection	6124874
47585603	47585626	X	+	27260156	CAL120	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.5150256222968568	[259]	[207,165,300]	-6	hSpCas9	negative selection	6124875
47619686	47619709	X	-	27260156	CADOES1	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.5856559416447634	[547]	[641,692,1000,721]	8	hSpCas9	negative selection	6180294
47619686	47619709	X	+	27260156	CADOES1	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.18618305478777408	[638]	[679,686,704,630]	3	hSpCas9	negative selection	6180295
47606959	47606982	X	-	27260156	CADOES1	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.15659565711061854	[393]	[342,424,457,407]	2	hSpCas9	negative selection	6180296
47584988	47585011	X	-	27260156	CADOES1	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.2771684854468236	[813]	[625,731,546,592]	-5	hSpCas9	negative selection	6181871
47585236	47585259	X	-	27260156	CADOES1	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.1046074123573355	[0]	[0,0,0,0]	1	hSpCas9	negative selection	6181872
47584934	47584957	X	+	27260156	CADOES1	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.4056115225877347	[410]	[549,615,392,464]	6	hSpCas9	negative selection	6181873
47606980	47607003	X	+	27260156	CADOES1	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.029599473438493118	[685]	[710,527,753,609]	0	hSpCas9	negative selection	6244547
47607181	47607204	X	-	27260156	CADOES1	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.057941970245753094	[161]	[129,167,107,223]	1	hSpCas9	negative selection	6244548
47607140	47607163	X	-	27260156	CADOES1	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	0.10572531427596375	[504]	[698,534,311,473]	1	hSpCas9	negative selection	6244549
47585294	47585317	X	+	27260156	CADOES1	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.18478537827659847	[221]	[222,168,164,168]	-3	hSpCas9	negative selection	6246124
47585629	47585652	X	+	27260156	CADOES1	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-1.0244791441159795	[220]	[124,60,142,73]	-9	hSpCas9	negative selection	6246125
47585603	47585626	X	+	27260156	CADOES1	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.022693494942479187	[259]	[230,229,341,176]	0	hSpCas9	negative selection	6246126
47619686	47619709	X	-	27260156	EWS502	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.7161174041219387	[547]	[892,915,987,1027]	9	hSpCas9	negative selection	6301545
47619686	47619709	X	+	27260156	EWS502	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.12692695328780812	[638]	[634,692,792,855]	2	hSpCas9	negative selection	6301546
47606959	47606982	X	-	27260156	EWS502	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.1113724776051396	[393]	[493,398,444,460]	2	hSpCas9	negative selection	6301547
47584988	47585011	X	-	27260156	EWS502	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.3393465328603638	[813]	[424,719,723,899]	-5	hSpCas9	negative selection	6303122
47585236	47585259	X	-	27260156	EWS502	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.08156866895534698	[0]	[0,0,0,0]	-1	hSpCas9	negative selection	6303123
47584934	47584957	X	+	27260156	EWS502	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.5662043027551409	[410]	[605,442,803,744]	8	hSpCas9	negative selection	6303124
47606980	47607003	X	+	27260156	EWS502	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.0020279197255189674	[685]	[775,767,783,551]	0	hSpCas9	negative selection	6365798
47607181	47607204	X	-	27260156	EWS502	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.4797397586840919	[161]	[135,128,94,129]	-7	hSpCas9	negative selection	6365799
47607140	47607163	X	-	27260156	EWS502	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.2238627879951695	[504]	[493,431,373,530]	-4	hSpCas9	negative selection	6365800
47585294	47585317	X	+	27260156	EWS502	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.2847709741497171	[221]	[84,226,250,222]	-5	hSpCas9	negative selection	6367375
47585629	47585652	X	+	27260156	EWS502	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.8210195417574475	[220]	[123,169,110,122]	-8	hSpCas9	negative selection	6367376
47585603	47585626	X	+	27260156	EWS502	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.402258097857894	[259]	[186,185,188,278]	-6	hSpCas9	negative selection	6367377
47619686	47619709	X	-	27260156	EW8	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.527157597713679	[547]	[778,577,479,762]	8	hSpCas9	negative selection	6422796
47619686	47619709	X	+	27260156	EW8	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	-0.01471434957201051	[638]	[544,577,380,570]	0	hSpCas9	negative selection	6422797
47606959	47606982	X	-	27260156	EW8	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	-0.23540554655936163	[393]	[261,189,297,327]	-4	hSpCas9	negative selection	6422798
47584988	47585011	X	-	27260156	EW8	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.4380230547594122	[813]	[479,546,408,522]	-7	hSpCas9	negative selection	6424373
47585236	47585259	X	-	27260156	EW8	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.30430985650646214	[0]	[0,0,0,0]	5	hSpCas9	negative selection	6424374
47584934	47584957	X	+	27260156	EW8	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.3259150875741421	[410]	[447,440,425,355]	6	hSpCas9	negative selection	6424375
47606980	47607003	X	+	27260156	EW8	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.2433768281582876	[685]	[417,558,391,515]	-4	hSpCas9	negative selection	6487049
47607181	47607204	X	-	27260156	EW8	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.2637968283292036	[161]	[163,134,81,66]	-5	hSpCas9	negative selection	6487050
47607140	47607163	X	-	27260156	EW8	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.36667024646439245	[504]	[344,287,332,302]	-6	hSpCas9	negative selection	6487051
47585294	47585317	X	+	27260156	EW8	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.014196440429319113	[221]	[262,110,232,104]	0	hSpCas9	negative selection	6488626
47585629	47585652	X	+	27260156	EW8	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.5972004137806337	[220]	[143,94,99,139]	-8	hSpCas9	negative selection	6488627
47585603	47585626	X	+	27260156	EW8	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.33470986255216717	[259]	[257,109,92,228]	-6	hSpCas9	negative selection	6488628
47619686	47619709	X	-	27260156	CORL105	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.36094471703131603	[547]	[866,762,886,790]	6	hSpCas9	negative selection	6544047
47619686	47619709	X	+	27260156	CORL105	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.23066404853214073	[638]	[794,837,957,929]	4	hSpCas9	negative selection	6544048
47606959	47606982	X	-	27260156	CORL105	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.2690183787674294	[393]	[607,433,618,575]	5	hSpCas9	negative selection	6544049
47584988	47585011	X	-	27260156	CORL105	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.17351648851187051	[813]	[761,711,1123,824]	-3	hSpCas9	negative selection	6545624
47585236	47585259	X	-	27260156	CORL105	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.22721281181091513	[0]	[0,0,0,0]	-4	hSpCas9	negative selection	6545625
47584934	47584957	X	+	27260156	CORL105	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.7261767465983509	[410]	[720,930,823,706]	9	hSpCas9	negative selection	6545626
47606980	47607003	X	+	27260156	CORL105	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.020297414191448926	[685]	[760,831,801,771]	0	hSpCas9	negative selection	6608300
47607181	47607204	X	-	27260156	CORL105	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.24617784150813615	[161]	[295,222,240,144]	4	hSpCas9	negative selection	6608301
47607140	47607163	X	-	27260156	CORL105	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.22740279848493206	[504]	[484,487,690,384]	-4	hSpCas9	negative selection	6608302
47585294	47585317	X	+	27260156	CORL105	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.6414273167287612	[221]	[168,221,168,105]	-8	hSpCas9	negative selection	6609877
47585629	47585652	X	+	27260156	CORL105	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.17290744876470576	[220]	[334,268,145,157]	-3	hSpCas9	negative selection	6609878
47585603	47585626	X	+	27260156	CORL105	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.24332983061747693	[259]	[222,305,185,299]	-4	hSpCas9	negative selection	6609879
47619686	47619709	X	-	27260156	HS294T	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.4793523084785717	[547]	[271,269,369,266]	6	hSpCas9	negative selection	6665298
47619686	47619709	X	+	27260156	HS294T	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.4058663961249698	[638]	[236,288,526,252]	5	hSpCas9	negative selection	6665299
47606959	47606982	X	-	27260156	HS294T	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.39138585076925386	[393]	[149,155,158,367]	5	hSpCas9	negative selection	6665300
47584988	47585011	X	-	27260156	HS294T	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	0.008781527288512447	[813]	[408,251,284,311]	0	hSpCas9	negative selection	6666875
47585236	47585259	X	-	27260156	HS294T	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	1.3721219085074186	[0]	[0,0,0,0]	9	hSpCas9	negative selection	6666876
47584934	47584957	X	+	27260156	HS294T	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.11637583615320649	[410]	[173,174,157,182]	1	hSpCas9	negative selection	6666877
47606980	47607003	X	+	27260156	HS294T	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.1100320771316351	[685]	[319,254,214,364]	1	hSpCas9	negative selection	6729551
47607181	47607204	X	-	27260156	HS294T	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.4981154091252682	[161]	[43,45,48,36]	-6	hSpCas9	negative selection	6729552
47607140	47607163	X	-	27260156	HS294T	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	0.057665648838395686	[504]	[90,336,269,103]	0	hSpCas9	negative selection	6729553
47585294	47585317	X	+	27260156	HS294T	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.25298390204122967	[221]	[37,125,69,51]	-4	hSpCas9	negative selection	6731128
47585629	47585652	X	+	27260156	HS294T	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	0.46313816662802443	[220]	[195,103,78,77]	6	hSpCas9	negative selection	6731129
47585603	47585626	X	+	27260156	HS294T	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.09957062804745498	[259]	[126,116,97,81]	1	hSpCas9	negative selection	6731130
47619686	47619709	X	-	27260156	HCC44	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.7694604100584467	[547]	[945,817,1234,1265]	9	hSpCas9	negative selection	6786549
47619686	47619709	X	+	27260156	HCC44	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.09914218465202151	[638]	[899,499,1132,672]	1	hSpCas9	negative selection	6786550
47606959	47606982	X	-	27260156	HCC44	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.3371018988754333	[393]	[515,439,640,672]	5	hSpCas9	negative selection	6786551
47584988	47585011	X	-	27260156	HCC44	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.41432651088018163	[813]	[872,526,509,850]	-6	hSpCas9	negative selection	6788126
47585236	47585259	X	-	27260156	HCC44	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.17453351620550883	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	6788127
47584934	47584957	X	+	27260156	HCC44	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.6215192530679301	[410]	[973,602,684,629]	8	hSpCas9	negative selection	6788128
47606980	47607003	X	+	27260156	HCC44	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.16807970736512629	[685]	[748,408,908,769]	-3	hSpCas9	negative selection	6850802
47607181	47607204	X	-	27260156	HCC44	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.3267055625526476	[161]	[161,97,124,200]	-5	hSpCas9	negative selection	6850803
47607140	47607163	X	-	27260156	HCC44	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.03617300864612627	[504]	[424,621,788,410]	0	hSpCas9	negative selection	6850804
47585294	47585317	X	+	27260156	HCC44	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.4286929085295794	[221]	[92,349,120,138]	-6	hSpCas9	negative selection	6852379
47585629	47585652	X	+	27260156	HCC44	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.8269488414325963	[220]	[148,108,216,106]	-8	hSpCas9	negative selection	6852380
47585603	47585626	X	+	27260156	HCC44	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.0879812748824178	[259]	[283,111,525,385]	1	hSpCas9	negative selection	6852381
47619686	47619709	X	-	27260156	G402	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.7250192314357752	[547]	[1281,1043,1267,856]	8	hSpCas9	negative selection	6907800
47619686	47619709	X	+	27260156	G402	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.27999794519158694	[638]	[1245,798,1168,619]	3	hSpCas9	negative selection	6907801
47606959	47606982	X	-	27260156	G402	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.6257985829954371	[393]	[710,867,659,728]	7	hSpCas9	negative selection	6907802
47584988	47585011	X	-	27260156	G402	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	0.02566639452920505	[813]	[1387,811,1142,752]	0	hSpCas9	negative selection	6909377
47585236	47585259	X	-	27260156	G402	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.28565990241013317	[0]	[0,0,0,0]	-4	hSpCas9	negative selection	6909378
47584934	47584957	X	+	27260156	G402	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.5934744742552086	[410]	[832,896,745,575]	7	hSpCas9	negative selection	6909379
47606980	47607003	X	+	27260156	G402	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.05022893378833143	[685]	[976,1130,767,416]	0	hSpCas9	negative selection	6972053
47607181	47607204	X	-	27260156	G402	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.45481949551896217	[161]	[274,515,151,159]	5	hSpCas9	negative selection	6972054
47607140	47607163	X	-	27260156	G402	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.2035909963465944	[504]	[332,965,380,457]	-3	hSpCas9	negative selection	6972055
47585294	47585317	X	+	27260156	G402	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.4575342091545599	[221]	[186,174,601,478]	5	hSpCas9	negative selection	6973630
47585629	47585652	X	+	27260156	G402	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-1.558018481657614	[220]	[95,55,172,41]	-9	hSpCas9	negative selection	6973631
47585603	47585626	X	+	27260156	G402	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.019314186803740085	[259]	[247,171,344,460]	0	hSpCas9	negative selection	6973632
47619686	47619709	X	-	27260156	L33	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.3604676020310186	[547]	[554,314,455,767]	7	hSpCas9	negative selection	7029051
47619686	47619709	X	+	27260156	L33	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.038506107233927445	[638]	[572,251,468,692]	0	hSpCas9	negative selection	7029052
47606959	47606982	X	-	27260156	L33	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.23822954855491363	[393]	[316,194,273,631]	5	hSpCas9	negative selection	7029053
47584988	47585011	X	-	27260156	L33	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.053389001898223376	[813]	[766,298,547,769]	-1	hSpCas9	negative selection	7030628
47585236	47585259	X	-	27260156	L33	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.5883332593072037	[0]	[0,0,0,0]	9	hSpCas9	negative selection	7030629
47584934	47584957	X	+	27260156	L33	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.10150411460197033	[410]	[311,170,363,458]	2	hSpCas9	negative selection	7030630
47606980	47607003	X	+	27260156	L33	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.27415170307276343	[685]	[627,222,366,511]	-6	hSpCas9	negative selection	7093304
47607181	47607204	X	-	27260156	L33	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.004560449879395412	[161]	[122,97,69,172]	0	hSpCas9	negative selection	7093305
47607140	47607163	X	-	27260156	L33	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.5676762574439116	[504]	[400,104,219,353]	-8	hSpCas9	negative selection	7093306
47585294	47585317	X	+	27260156	L33	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.2632245665985813	[221]	[189,78,86,217]	-6	hSpCas9	negative selection	7094881
47585629	47585652	X	+	27260156	L33	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.03842687523887478	[220]	[187,90,117,262]	-1	hSpCas9	negative selection	7094882
47585603	47585626	X	+	27260156	L33	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.10523213815554455	[259]	[175,79,148,358]	-2	hSpCas9	negative selection	7094883
47619686	47619709	X	-	27260156	K562	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	1.264274713185281	[547]	[1356,729,1677,923]	9	hSpCas9	negative selection	7150302
47619686	47619709	X	+	27260156	K562	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.09093492732010655	[638]	[802,633,388,604]	1	hSpCas9	negative selection	7150303
47606959	47606982	X	-	27260156	K562	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.1719598831633433	[393]	[326,574,253,418]	2	hSpCas9	negative selection	7150304
47584988	47585011	X	-	27260156	K562	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	0.10830201978344445	[813]	[938,914,652,640]	1	hSpCas9	negative selection	7151879
47585236	47585259	X	-	27260156	K562	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.1738498320762858	[0]	[0,0,0,0]	2	hSpCas9	negative selection	7151880
47584934	47584957	X	+	27260156	K562	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.49564990294998035	[410]	[419,751,329,552]	6	hSpCas9	negative selection	7151881
47606980	47607003	X	+	27260156	K562	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.48410125092221234	[685]	[1220,536,484,1138]	6	hSpCas9	negative selection	7214555
47607181	47607204	X	-	27260156	K562	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.31875753040061783	[161]	[359,133,150,93]	4	hSpCas9	negative selection	7214556
47607140	47607163	X	-	27260156	K562	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.6322912195944489	[504]	[150,237,403,341]	-6	hSpCas9	negative selection	7214557
47585294	47585317	X	+	27260156	K562	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.12486128975256539	[221]	[191,273,205,68]	-1	hSpCas9	negative selection	7216132
47585629	47585652	X	+	27260156	K562	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.15052466305508583	[220]	[221,188,156,145]	-2	hSpCas9	negative selection	7216133
47585603	47585626	X	+	27260156	K562	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.17510169683478816	[259]	[260,560,155,97]	2	hSpCas9	negative selection	7216134
47619686	47619709	X	-	27260156	HT29	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.6351472271650641	[547]	[1391,894,767,1084]	9	hSpCas9	negative selection	7271553
47619686	47619709	X	+	27260156	HT29	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.1856106008854419	[638]	[928,1001,798,818]	3	hSpCas9	negative selection	7271554
47606959	47606982	X	-	27260156	HT29	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.14322521578350347	[393]	[901,467,385,395]	2	hSpCas9	negative selection	7271555
47584988	47585011	X	-	27260156	HT29	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.16792986993399894	[813]	[865,751,1063,828]	-3	hSpCas9	negative selection	7273130
47585236	47585259	X	-	27260156	HT29	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.27901894800515237	[0]	[0,0,0,0]	-5	hSpCas9	negative selection	7273131
47584934	47584957	X	+	27260156	HT29	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.48695728671980676	[410]	[769,856,688,520]	8	hSpCas9	negative selection	7273132
47606980	47607003	X	+	27260156	HT29	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.12446769231096982	[685]	[915,939,603,636]	-3	hSpCas9	negative selection	7335806
47607181	47607204	X	-	27260156	HT29	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.22293817477372668	[161]	[157,136,222,153]	-4	hSpCas9	negative selection	7335807
47607140	47607163	X	-	27260156	HT29	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.14361910852139007	[504]	[603,776,416,455]	-3	hSpCas9	negative selection	7335808
47585294	47585317	X	+	27260156	HT29	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.26379696249699935	[221]	[365,143,279,123]	-5	hSpCas9	negative selection	7337383
47585629	47585652	X	+	27260156	HT29	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.6382094583849227	[220]	[255,126,138,169]	-8	hSpCas9	negative selection	7337384
47585603	47585626	X	+	27260156	HT29	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.0667301762074799	[259]	[331,268,315,288]	-1	hSpCas9	negative selection	7337385
47619686	47619709	X	-	27260156	MHHES1	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.3246153071154697	[547]	[893,593,1105,534]	6	hSpCas9	negative selection	7392804
47619686	47619709	X	+	27260156	MHHES1	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.17077599757800788	[638]	[1113,1020,768,458]	3	hSpCas9	negative selection	7392805
47606959	47606982	X	-	27260156	MHHES1	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.4846491525518761	[393]	[643,617,631,585]	8	hSpCas9	negative selection	7392806
47584988	47585011	X	-	27260156	MHHES1	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	0.026939378172663453	[813]	[993,1407,817,622]	0	hSpCas9	negative selection	7394381
47585236	47585259	X	-	27260156	MHHES1	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.1630968580950416	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	7394382
47584934	47584957	X	+	27260156	MHHES1	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.23065386032154425	[410]	[613,425,675,460]	4	hSpCas9	negative selection	7394383
47606980	47607003	X	+	27260156	MHHES1	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.047946433978092395	[685]	[898,809,722,764]	0	hSpCas9	negative selection	7457057
47607181	47607204	X	-	27260156	MHHES1	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.030065057713283716	[161]	[155,96,206,227]	0	hSpCas9	negative selection	7457058
47607140	47607163	X	-	27260156	MHHES1	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.30985570195736417	[504]	[519,369,488,446]	-5	hSpCas9	negative selection	7457059
47585294	47585317	X	+	27260156	MHHES1	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.141977822518913	[221]	[150,439,222,123]	-3	hSpCas9	negative selection	7458634
47585629	47585652	X	+	27260156	MHHES1	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.4972101703001215	[220]	[190,213,152,153]	-7	hSpCas9	negative selection	7458635
47585603	47585626	X	+	27260156	MHHES1	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.015110823665949735	[259]	[509,244,203,248]	0	hSpCas9	negative selection	7458636
47619686	47619709	X	-	27260156	MEWO	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.49823514319967876	[547]	[858,611,727]	8	hSpCas9	negative selection	7514055
47619686	47619709	X	+	27260156	MEWO	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.05452017946799337	[638]	[762,609,516]	1	hSpCas9	negative selection	7514056
47606959	47606982	X	-	27260156	MEWO	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.18841892851788522	[393]	[446,469,347]	4	hSpCas9	negative selection	7514057
47584988	47585011	X	-	27260156	MEWO	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	0.009811737130947629	[813]	[962,783,590]	0	hSpCas9	negative selection	7515632
47585236	47585259	X	-	27260156	MEWO	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.09620936660807722	[0]	[0,0,0]	2	hSpCas9	negative selection	7515633
47584934	47584957	X	+	27260156	MEWO	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.15530163692580673	[410]	[501,397,398]	3	hSpCas9	negative selection	7515634
47606980	47607003	X	+	27260156	MEWO	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.0029167447885863895	[685]	[730,472,742]	0	hSpCas9	negative selection	7578308
47607181	47607204	X	-	27260156	MEWO	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.15591160328601283	[161]	[159,131,212]	3	hSpCas9	negative selection	7578309
47607140	47607163	X	-	27260156	MEWO	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.3864200716157507	[504]	[532,255,328]	-7	hSpCas9	negative selection	7578310
47585294	47585317	X	+	27260156	MEWO	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.35372481443323056	[221]	[204,119,170]	-6	hSpCas9	negative selection	7579885
47585629	47585652	X	+	27260156	MEWO	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.20333054989508859	[220]	[226,155,164]	-4	hSpCas9	negative selection	7579886
47585603	47585626	X	+	27260156	MEWO	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.1953298172028215	[259]	[295,250,291]	4	hSpCas9	negative selection	7579887
47619686	47619709	X	-	27260156	LNCAPCLONEFGC	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.842452227072198	[547]	[993,734,1010,845]	9	hSpCas9	negative selection	7635306
47619686	47619709	X	+	27260156	LNCAPCLONEFGC	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.2927182800231747	[638]	[782,513,936,646]	4	hSpCas9	negative selection	7635307
47606959	47606982	X	-	27260156	LNCAPCLONEFGC	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.9118131366429276	[393]	[726,491,709,772]	9	hSpCas9	negative selection	7635308
47584988	47585011	X	-	27260156	LNCAPCLONEFGC	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.07566489416177291	[813]	[735,853,676,516]	-1	hSpCas9	negative selection	7636883
47585236	47585259	X	-	27260156	LNCAPCLONEFGC	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.14289828313858877	[0]	[0,0,0,0]	2	hSpCas9	negative selection	7636884
47584934	47584957	X	+	27260156	LNCAPCLONEFGC	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.37179675038924426	[410]	[580,478,488,376]	6	hSpCas9	negative selection	7636885
47606980	47607003	X	+	27260156	LNCAPCLONEFGC	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.00216647849433127	[685]	[448,624,791,643]	0	hSpCas9	negative selection	7699559
47607181	47607204	X	-	27260156	LNCAPCLONEFGC	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.18751090539146076	[161]	[117,183,212,159]	3	hSpCas9	negative selection	7699560
47607140	47607163	X	-	27260156	LNCAPCLONEFGC	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.0749130905815665	[504]	[431,444,391,460]	-1	hSpCas9	negative selection	7699561
47585294	47585317	X	+	27260156	LNCAPCLONEFGC	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.027820594838741775	[221]	[111,165,303,256]	0	hSpCas9	negative selection	7701136
47585629	47585652	X	+	27260156	LNCAPCLONEFGC	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	0.033050141132017874	[220]	[262,281,130,125]	0	hSpCas9	negative selection	7701137
47585603	47585626	X	+	27260156	LNCAPCLONEFGC	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.32548364948523156	[259]	[222,392,279,276]	5	hSpCas9	negative selection	7701138
47619686	47619709	X	-	27260156	PANC0327	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.6584086702576982	[547]	[1236,594,755,545]	8	hSpCas9	negative selection	7756557
47619686	47619709	X	+	27260156	PANC0327	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	-0.10764689730326149	[638]	[644,493,491,489]	-2	hSpCas9	negative selection	7756558
47606959	47606982	X	-	27260156	PANC0327	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.2807969379284675	[393]	[725,234,462,325]	4	hSpCas9	negative selection	7756559
47584988	47585011	X	-	27260156	PANC0327	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.4003862833310861	[813]	[648,587,366,589]	-5	hSpCas9	negative selection	7758134
47585236	47585259	X	-	27260156	PANC0327	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.17097580133514256	[0]	[0,0,0,0]	2	hSpCas9	negative selection	7758135
47584934	47584957	X	+	27260156	PANC0327	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.6640020190595145	[410]	[496,526,734,554]	8	hSpCas9	negative selection	7758136
47606980	47607003	X	+	27260156	PANC0327	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.15371859268307353	[685]	[746,593,742,643]	2	hSpCas9	negative selection	7820810
47607181	47607204	X	-	27260156	PANC0327	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.021086990218568635	[161]	[110,200,104,139]	0	hSpCas9	negative selection	7820811
47607140	47607163	X	-	27260156	PANC0327	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.19934471156048178	[504]	[263,416,453,413]	-3	hSpCas9	negative selection	7820812
47585294	47585317	X	+	27260156	PANC0327	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.3204302396983343	[221]	[275,210,285,218]	5	hSpCas9	negative selection	7822387
47585629	47585652	X	+	27260156	PANC0327	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	0.010465554914407926	[220]	[236,204,98,251]	0	hSpCas9	negative selection	7822388
47585603	47585626	X	+	27260156	PANC0327	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.5872186287160046	[259]	[137,95,155,230]	-7	hSpCas9	negative selection	7822389
47619686	47619709	X	-	27260156	NCIH2009	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.8362336971354648	[547]	[1504,1358,1261]	9	hSpCas9	negative selection	7877808
47619686	47619709	X	+	27260156	NCIH2009	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.4351305873851422	[638]	[1210,1203,1204]	6	hSpCas9	negative selection	7877809
47606959	47606982	X	-	27260156	NCIH2009	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.5554133607524994	[393]	[608,810,965]	7	hSpCas9	negative selection	7877810
47584988	47585011	X	-	27260156	NCIH2009	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.1080575780572598	[813]	[1355,1016,850]	-1	hSpCas9	negative selection	7879385
47585236	47585259	X	-	27260156	NCIH2009	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.4816251237464222	[0]	[0,0,0]	-6	hSpCas9	negative selection	7879386
47584934	47584957	X	+	27260156	NCIH2009	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.5336252819970884	[410]	[901,956,644]	7	hSpCas9	negative selection	7879387
47606980	47607003	X	+	27260156	NCIH2009	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.221914853843176	[685]	[1286,1062,1035]	3	hSpCas9	negative selection	7942061
47607181	47607204	X	-	27260156	NCIH2009	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.04572591995221953	[161]	[260,227,216]	0	hSpCas9	negative selection	7942062
47607140	47607163	X	-	27260156	NCIH2009	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.23368513939718488	[504]	[671,564,576]	-3	hSpCas9	negative selection	7942063
47585294	47585317	X	+	27260156	NCIH2009	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.3361369103194931	[221]	[410,436,328]	4	hSpCas9	negative selection	7943638
47585629	47585652	X	+	27260156	NCIH2009	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	0.20279728518548834	[220]	[708,212,215]	2	hSpCas9	negative selection	7943639
47585603	47585626	X	+	27260156	NCIH2009	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.16348423266647605	[259]	[303,600,290]	2	hSpCas9	negative selection	7943640
47619686	47619709	X	-	27260156	NCIH1373	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.9008703088486766	[547]	[1117,924,1112,384]	8	hSpCas9	negative selection	7999059
47619686	47619709	X	+	27260156	NCIH1373	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.4055741816981515	[638]	[1190,1137,671,210]	4	hSpCas9	negative selection	7999060
47606959	47606982	X	-	27260156	NCIH1373	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.9295691947061148	[393]	[681,573,1121,259]	8	hSpCas9	negative selection	7999061
47584988	47585011	X	-	27260156	NCIH1373	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	0.02443099524623915	[813]	[1017,1125,835,185]	0	hSpCas9	negative selection	8000636
47585236	47585259	X	-	27260156	NCIH1373	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.5801096359471138	[0]	[0,0,0,0]	6	hSpCas9	negative selection	8000637
47584934	47584957	X	+	27260156	NCIH1373	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.46586841353081254	[410]	[518,742,813,109]	4	hSpCas9	negative selection	8000638
47606980	47607003	X	+	27260156	NCIH1373	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.053278957099090585	[685]	[909,619,594,232]	0	hSpCas9	negative selection	8063312
47607181	47607204	X	-	27260156	NCIH1373	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.6507800215815166	[161]	[137,503,257,48]	6	hSpCas9	negative selection	8063313
47607140	47607163	X	-	27260156	NCIH1373	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	0.13872730319091303	[504]	[962,354,646,158]	1	hSpCas9	negative selection	8063314
47585294	47585317	X	+	27260156	NCIH1373	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.7174487563973926	[221]	[174,156,193,19]	-6	hSpCas9	negative selection	8064889
47585629	47585652	X	+	27260156	NCIH1373	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	0.8414092076757602	[220]	[1003,260,224,102]	8	hSpCas9	negative selection	8064890
47585603	47585626	X	+	27260156	NCIH1373	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.7557146805082915	[259]	[240,160,114,48]	-6	hSpCas9	negative selection	8064891
47619686	47619709	X	-	27260156	PATU8902	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	1.2963489246047817	[547]	[2413,1865,1385,1944]	9	hSpCas9	negative selection	8120310
47619686	47619709	X	+	27260156	PATU8902	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.2702953487346813	[638]	[1498,872,937,993]	2	hSpCas9	negative selection	8120311
47606959	47606982	X	-	27260156	PATU8902	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.372194323236467	[393]	[547,766,506,1116]	4	hSpCas9	negative selection	8120312
47584988	47585011	X	-	27260156	PATU8902	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	0.22842985141952787	[813]	[1519,1166,1053,1669]	2	hSpCas9	negative selection	8121887
47585236	47585259	X	-	27260156	PATU8902	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.47507721586162077	[0]	[0,0,0,0]	-5	hSpCas9	negative selection	8121888
47584934	47584957	X	+	27260156	PATU8902	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.8563428639257349	[410]	[961,1022,1227,852]	8	hSpCas9	negative selection	8121889
47606980	47607003	X	+	27260156	PATU8902	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.6684288473497421	[685]	[1801,2164,962,1240]	7	hSpCas9	negative selection	8184563
47607181	47607204	X	-	27260156	PATU8902	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.24656529593396792	[161]	[123,212,267,491]	2	hSpCas9	negative selection	8184564
47607140	47607163	X	-	27260156	PATU8902	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	0.16086656585657	[504]	[964,646,691,865]	1	hSpCas9	negative selection	8184565
47585294	47585317	X	+	27260156	PATU8902	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.17607511164838585	[221]	[161,437,141,401]	-2	hSpCas9	negative selection	8186140
47585629	47585652	X	+	27260156	PATU8902	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	1.0567629065543251	[220]	[490,474,497,1196]	9	hSpCas9	negative selection	8186141
47585603	47585626	X	+	27260156	PATU8902	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.6388303892663755	[259]	[370,992,202,810]	6	hSpCas9	negative selection	8186142
47619686	47619709	X	-	27260156	PANC1	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.6024309038571026	[547]	[830,855,608,595]	8	hSpCas9	negative selection	8241561
47619686	47619709	X	+	27260156	PANC1	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	-0.00834764830758794	[638]	[601,594,580,424]	0	hSpCas9	negative selection	8241562
47606959	47606982	X	-	27260156	PANC1	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.24776875383630245	[393]	[278,701,347,344]	4	hSpCas9	negative selection	8241563
47584988	47585011	X	-	27260156	PANC1	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	0.06010603251948443	[813]	[575,977,823,601]	0	hSpCas9	negative selection	8243138
47585236	47585259	X	-	27260156	PANC1	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.22557163962344795	[0]	[0,0,0,0]	3	hSpCas9	negative selection	8243139
47584934	47584957	X	+	27260156	PANC1	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.325707712819743	[410]	[327,664,460,368]	5	hSpCas9	negative selection	8243140
47606980	47607003	X	+	27260156	PANC1	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.27010395534581755	[685]	[673,876,891,464]	4	hSpCas9	negative selection	8305814
47607181	47607204	X	-	27260156	PANC1	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.23077769119371827	[161]	[102,222,180,157]	3	hSpCas9	negative selection	8305815
47607140	47607163	X	-	27260156	PANC1	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	0.25955228312539436	[504]	[546,534,558,442]	4	hSpCas9	negative selection	8305816
47585294	47585317	X	+	27260156	PANC1	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.1681187630813229	[221]	[89,296,208,267]	2	hSpCas9	negative selection	8307391
47585629	47585652	X	+	27260156	PANC1	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	0.49737052048423924	[220]	[177,369,311,235]	7	hSpCas9	negative selection	8307392
47585603	47585626	X	+	27260156	PANC1	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.5527787813079887	[259]	[345,399,293,285]	8	hSpCas9	negative selection	8307393
47619686	47619709	X	-	27260156	PANC0813	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.5525784347647642	[547]	[1079,617,1117,970]	8	hSpCas9	negative selection	8362812
47619686	47619709	X	+	27260156	PANC0813	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.18193713064165928	[638]	[813,1048,820,723]	3	hSpCas9	negative selection	8362813
47606959	47606982	X	-	27260156	PANC0813	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.20378088805745082	[393]	[534,565,613,422]	3	hSpCas9	negative selection	8362814
47584988	47585011	X	-	27260156	PANC0813	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.03314889264658272	[813]	[981,984,1059,725]	0	hSpCas9	negative selection	8364389
47585236	47585259	X	-	27260156	PANC0813	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.23161252818376	[0]	[0,0,0,0]	-4	hSpCas9	negative selection	8364390
47584934	47584957	X	+	27260156	PANC0813	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.5752345463038632	[410]	[849,679,831,536]	8	hSpCas9	negative selection	8364391
47606980	47607003	X	+	27260156	PANC0813	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.013181535003482181	[685]	[754,1050,659,780]	0	hSpCas9	negative selection	8427065
47607181	47607204	X	-	27260156	PANC0813	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.18738356637751918	[161]	[142,301,241,174]	3	hSpCas9	negative selection	8427066
47607140	47607163	X	-	27260156	PANC0813	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.3949591327707781	[504]	[509,319,619,364]	-6	hSpCas9	negative selection	8427067
47585294	47585317	X	+	27260156	PANC0813	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.08114564293430893	[221]	[264,193,289,238]	-1	hSpCas9	negative selection	8428642
47585629	47585652	X	+	27260156	PANC0813	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.13469853667402343	[220]	[150,228,270,283]	-2	hSpCas9	negative selection	8428643
47585603	47585626	X	+	27260156	PANC0813	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.17066246236095206	[259]	[373,360,314,327]	2	hSpCas9	negative selection	8428644
47619686	47619709	X	-	27260156	RDES	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.8343604763546334	[547]	[1039,1149,1116,1172]	9	hSpCas9	negative selection	8484063
47619686	47619709	X	+	27260156	RDES	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.2792501020434891	[638]	[840,801,1023,895]	4	hSpCas9	negative selection	8484064
47606959	47606982	X	-	27260156	RDES	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.10025753933965273	[393]	[337,530,561,535]	1	hSpCas9	negative selection	8484065
47584988	47585011	X	-	27260156	RDES	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.18882800202175765	[813]	[622,771,834,1125]	-3	hSpCas9	negative selection	8485640
47585236	47585259	X	-	27260156	RDES	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.18942035355372333	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	8485641
47584934	47584957	X	+	27260156	RDES	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.624152858566845	[410]	[663,685,725,850]	8	hSpCas9	negative selection	8485642
47606980	47607003	X	+	27260156	RDES	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.026760679772696916	[685]	[642,801,796,872]	0	hSpCas9	negative selection	8548316
47607181	47607204	X	-	27260156	RDES	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.155708807246264	[161]	[129,139,338,250]	2	hSpCas9	negative selection	8548317
47607140	47607163	X	-	27260156	RDES	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.0579332186541508	[504]	[501,488,625,628]	-1	hSpCas9	negative selection	8548318
47585294	47585317	X	+	27260156	RDES	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.15210511219946365	[221]	[298,235,271,324]	2	hSpCas9	negative selection	8549893
47585629	47585652	X	+	27260156	RDES	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.4479210232014361	[220]	[143,165,239,205]	-6	hSpCas9	negative selection	8549894
47585603	47585626	X	+	27260156	RDES	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.11948071785557335	[259]	[210,377,283,454]	2	hSpCas9	negative selection	8549895
47619686	47619709	X	-	27260156	PC3	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.467781176753186	[547]	[485,759,1112,847]	8	hSpCas9	negative selection	8605314
47619686	47619709	X	+	27260156	PC3	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.15800295622935345	[638]	[420,894,1049,654]	3	hSpCas9	negative selection	8605315
47606959	47606982	X	-	27260156	PC3	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.3715357728847977	[393]	[328,503,741,578]	7	hSpCas9	negative selection	8605316
47584988	47585011	X	-	27260156	PC3	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	0.053229274758055056	[813]	[576,643,1382,1021]	1	hSpCas9	negative selection	8606891
47585236	47585259	X	-	27260156	PC3	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.05753347684474441	[0]	[0,0,0,0]	1	hSpCas9	negative selection	8606892
47584934	47584957	X	+	27260156	PC3	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.28209128289582563	[410]	[251,451,997,558]	6	hSpCas9	negative selection	8606893
47606980	47607003	X	+	27260156	PC3	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.1771318845011236	[685]	[533,1033,1064,568]	4	hSpCas9	negative selection	8669567
47607181	47607204	X	-	27260156	PC3	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.34753353828466027	[161]	[99,163,472,222]	7	hSpCas9	negative selection	8669568
47607140	47607163	X	-	27260156	PC3	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.45046024700675813	[504]	[305,333,613,294]	-8	hSpCas9	negative selection	8669569
47585294	47585317	X	+	27260156	PC3	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.24110172671553198	[221]	[154,221,136,203]	-5	hSpCas9	negative selection	8671144
47585629	47585652	X	+	27260156	PC3	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.695652614478339	[220]	[73,126,259,147]	-9	hSpCas9	negative selection	8671145
47585603	47585626	X	+	27260156	PC3	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.0006615642853293746	[259]	[143,260,429,297]	0	hSpCas9	negative selection	8671146
47619686	47619709	X	-	27260156	PATU8988T	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.39734523401469213	[547]	[642,773,574,815]	6	hSpCas9	negative selection	8726565
47619686	47619709	X	+	27260156	PATU8988T	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	-0.3695935690433779	[638]	[637,317,431,511]	-6	hSpCas9	negative selection	8726566
47606959	47606982	X	-	27260156	PATU8988T	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.24702526222672194	[393]	[517,529,349,414]	4	hSpCas9	negative selection	8726567
47584988	47585011	X	-	27260156	PATU8988T	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.3200231693557477	[813]	[350,928,501,779]	-5	hSpCas9	negative selection	8728142
47585236	47585259	X	-	27260156	PATU8988T	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.04952519822641044	[0]	[0,0,0,0]	0	hSpCas9	negative selection	8728143
47584934	47584957	X	+	27260156	PATU8988T	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.43358964333982897	[410]	[458,656,525,512]	7	hSpCas9	negative selection	8728144
47606980	47607003	X	+	27260156	PATU8988T	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.20424302573670444	[685]	[689,757,575,269]	-3	hSpCas9	negative selection	8790818
47607181	47607204	X	-	27260156	PATU8988T	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.7410932772627127	[161]	[132,248,276,396]	9	hSpCas9	negative selection	8790819
47607140	47607163	X	-	27260156	PATU8988T	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	0.01852954914495128	[504]	[527,480,561,395]	0	hSpCas9	negative selection	8790820
47585294	47585317	X	+	27260156	PATU8988T	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.14430410904818558	[221]	[194,208,349,185]	2	hSpCas9	negative selection	8792395
47585629	47585652	X	+	27260156	PATU8988T	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.04484938348752343	[220]	[305,259,149,109]	-1	hSpCas9	negative selection	8792396
47585603	47585626	X	+	27260156	PATU8988T	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.043422706594535954	[259]	[157,184,289,343]	0	hSpCas9	negative selection	8792397
47619686	47619709	X	-	27260156	T47D	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.5775826419686791	[547]	[965,823,973,1060]	9	hSpCas9	negative selection	8847816
47619686	47619709	X	+	27260156	T47D	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.193108008119787	[638]	[937,787,853,828]	4	hSpCas9	negative selection	8847817
47606959	47606982	X	-	27260156	T47D	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.20877191528784428	[393]	[549,537,473,560]	4	hSpCas9	negative selection	8847818
47584988	47585011	X	-	27260156	T47D	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.20225439503417275	[813]	[858,683,904,860]	-4	hSpCas9	negative selection	8849393
47585236	47585259	X	-	27260156	T47D	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.2201891943612022	[0]	[0,0,0,0]	-5	hSpCas9	negative selection	8849394
47584934	47584957	X	+	27260156	T47D	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.32081846729784	[410]	[671,585,584,548]	6	hSpCas9	negative selection	8849395
47606980	47607003	X	+	27260156	T47D	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.17761781477392546	[685]	[768,658,751,647]	-4	hSpCas9	negative selection	8912069
47607181	47607204	X	-	27260156	T47D	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.08501204331205625	[161]	[172,186,150,200]	-2	hSpCas9	negative selection	8912070
47607140	47607163	X	-	27260156	T47D	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.11574951083902565	[504]	[585,563,579,435]	-3	hSpCas9	negative selection	8912071
47585294	47585317	X	+	27260156	T47D	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.02035868271595387	[221]	[300,184,299,238]	0	hSpCas9	negative selection	8913646
47585629	47585652	X	+	27260156	T47D	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.6160295901844235	[220]	[161,143,167,200]	-8	hSpCas9	negative selection	8913647
47585603	47585626	X	+	27260156	T47D	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.18775058519008125	[259]	[378,260,389,356]	4	hSpCas9	negative selection	8913648
47619686	47619709	X	-	27260156	SU8686	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.7051306038781108	[547]	[734,861,886,1108]	9	hSpCas9	negative selection	8969067
47619686	47619709	X	+	27260156	SU8686	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.19833023504577152	[638]	[683,620,684,968]	3	hSpCas9	negative selection	8969068
47606959	47606982	X	-	27260156	SU8686	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.2716238808413041	[393]	[368,515,429,591]	4	hSpCas9	negative selection	8969069
47584988	47585011	X	-	27260156	SU8686	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.2008573534702246	[813]	[628,625,596,1017]	-3	hSpCas9	negative selection	8970644
47585236	47585259	X	-	27260156	SU8686	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.015103263740369854	[0]	[0,0,0,0]	0	hSpCas9	negative selection	8970645
47584934	47584957	X	+	27260156	SU8686	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.1939302985856233	[410]	[284,496,461,665]	3	hSpCas9	negative selection	8970646
47606980	47607003	X	+	27260156	SU8686	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.12923081636241474	[685]	[585,637,799,1024]	2	hSpCas9	negative selection	9033320
47607181	47607204	X	-	27260156	SU8686	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.28085039967508507	[161]	[81,115,143,205]	-5	hSpCas9	negative selection	9033321
47607140	47607163	X	-	27260156	SU8686	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	0.03863925295301977	[504]	[367,391,654,705]	0	hSpCas9	negative selection	9033322
47585294	47585317	X	+	27260156	SU8686	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.5781111061705169	[221]	[108,152,135,202]	-7	hSpCas9	negative selection	9034897
47585629	47585652	X	+	27260156	SU8686	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.2324959157276174	[220]	[162,213,238,117]	-4	hSpCas9	negative selection	9034898
47585603	47585626	X	+	27260156	SU8686	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.11108069821875577	[259]	[221,248,340,317]	1	hSpCas9	negative selection	9034899
47619686	47619709	X	-	27260156	SKES1	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.4200527600699815	[547]	[793,876,704,585]	8	hSpCas9	negative selection	9090318
47619686	47619709	X	+	27260156	SKES1	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	-0.078456000993198	[638]	[770,605,662,413]	-2	hSpCas9	negative selection	9090319
47606959	47606982	X	-	27260156	SKES1	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.5721159515532522	[393]	[613,626,596,510]	9	hSpCas9	negative selection	9090320
47584988	47585011	X	-	27260156	SKES1	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.3822146802757015	[813]	[571,802,611,524]	-7	hSpCas9	negative selection	9091895
47585236	47585259	X	-	27260156	SKES1	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.007546427030755254	[0]	[0,0,0,0]	0	hSpCas9	negative selection	9091896
47584934	47584957	X	+	27260156	SKES1	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.2381731520733941	[410]	[573,463,561,353]	5	hSpCas9	negative selection	9091897
47606980	47607003	X	+	27260156	SKES1	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.08617453770288253	[685]	[829,823,436,824]	2	hSpCas9	negative selection	9154571
47607181	47607204	X	-	27260156	SKES1	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	0.48073720982858226	[161]	[135,249,210,285]	8	hSpCas9	negative selection	9154572
47607140	47607163	X	-	27260156	SKES1	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.3926121326644848	[504]	[306,424,410,381]	-7	hSpCas9	negative selection	9154573
47585294	47585317	X	+	27260156	SKES1	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	0.04655216394556949	[221]	[292,213,161,248]	1	hSpCas9	negative selection	9156148
47585629	47585652	X	+	27260156	SKES1	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.2836150058785538	[220]	[174,201,151,193]	-6	hSpCas9	negative selection	9156149
47585603	47585626	X	+	27260156	SKES1	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.040183014610794654	[259]	[280,372,228,153]	-1	hSpCas9	negative selection	9156150
47619686	47619709	X	-	27260156	TOV112D	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.6461528917535092	[547]	[1296,702,578,853]	9	hSpCas9	negative selection	9211569
47619686	47619709	X	+	27260156	TOV112D	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.6089107648627319	[638]	[959,1825,586,743]	9	hSpCas9	negative selection	9211570
47606959	47606982	X	-	27260156	TOV112D	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.033137981002749145	[393]	[331,422,376,478]	0	hSpCas9	negative selection	9211571
47584988	47585011	X	-	27260156	TOV112D	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.2816838215902503	[813]	[669,698,378,932]	-5	hSpCas9	negative selection	9213146
47585236	47585259	X	-	27260156	TOV112D	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.0015868904355240687	[0]	[0,0,0,0]	0	hSpCas9	negative selection	9213147
47584934	47584957	X	+	27260156	TOV112D	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.10044304475192527	[410]	[397,732,380,323]	2	hSpCas9	negative selection	9213148
47606980	47607003	X	+	27260156	TOV112D	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.35755097732512275	[685]	[585,478,670,401]	-6	hSpCas9	negative selection	9275822
47607181	47607204	X	-	27260156	TOV112D	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.26096890167952247	[161]	[230,85,110,109]	-5	hSpCas9	negative selection	9275823
47607140	47607163	X	-	27260156	TOV112D	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.09470716148907161	[504]	[717,373,401,397]	-2	hSpCas9	negative selection	9275824
47585294	47585317	X	+	27260156	TOV112D	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.23990328610080947	[221]	[107,173,143,312]	-5	hSpCas9	negative selection	9277399
47585629	47585652	X	+	27260156	TOV112D	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	0.07468593804805312	[220]	[186,205,241,284]	1	hSpCas9	negative selection	9277400
47585603	47585626	X	+	27260156	TOV112D	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	-0.1862225614370947	[259]	[162,250,235,263]	-4	hSpCas9	negative selection	9277401
47619686	47619709	X	-	27260156	TC71	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.44370163051792344	[547]	[720,816,793,869]	8	hSpCas9	negative selection	9332820
47619686	47619709	X	+	27260156	TC71	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.06670308730267616	[638]	[707,820,622,720]	1	hSpCas9	negative selection	9332821
47606959	47606982	X	-	27260156	TC71	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.027828659909899994	[393]	[394,450,490,380]	0	hSpCas9	negative selection	9332822
47584988	47585011	X	-	27260156	TC71	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	-0.18290040903400695	[813]	[880,724,712,753]	-5	hSpCas9	negative selection	9334397
47585236	47585259	X	-	27260156	TC71	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	-0.10019163119465624	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	9334398
47584934	47584957	X	+	27260156	TC71	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.2685799470045954	[410]	[491,509,546,576]	6	hSpCas9	negative selection	9334399
47606980	47607003	X	+	27260156	TC71	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	0.01816222928217537	[685]	[660,764,761,794]	0	hSpCas9	negative selection	9397073
47607181	47607204	X	-	27260156	TC71	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.23195957454133276	[161]	[181,111,184,107]	-6	hSpCas9	negative selection	9397074
47607140	47607163	X	-	27260156	TC71	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.41372595142005436	[504]	[446,365,370,443]	-8	hSpCas9	negative selection	9397075
47585294	47585317	X	+	27260156	TC71	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.07871623926956617	[221]	[235,195,257,208]	-2	hSpCas9	negative selection	9398650
47585629	47585652	X	+	27260156	TC71	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.4239155277401825	[220]	[151,186,164,204]	-8	hSpCas9	negative selection	9398651
47585603	47585626	X	+	27260156	TC71	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.21418564836969534	[259]	[350,394,263,281]	5	hSpCas9	negative selection	9398652
47619686	47619709	X	-	27260156	TC32	viability	CCTGTCGGACAGCAACTTTATGG	SYN1	ENSG00000008056	0.8123820188811796	[547]	[831,610,1293,1022]	9	hSpCas9	negative selection	9454071
47619686	47619709	X	+	27260156	TC32	viability	CCATAAAGTTGCTGTCCGACAGG	SYN1	ENSG00000008056	0.12901567312025153	[638]	[619,442,737,900]	2	hSpCas9	negative selection	9454072
47606959	47606982	X	-	27260156	TC32	viability	ATATGGAAGTTCTTCGGAATGGG	SYN1	ENSG00000008056	0.5025383463764702	[393]	[411,508,628,554]	8	hSpCas9	negative selection	9454073
47584988	47585011	X	-	27260156	TC32	viability	TCATCTTGATCTCATAACGCTGG	SYN1	ENSG00000008056	0.007902617388728772	[813]	[668,544,1151,833]	0	hSpCas9	negative selection	9455648
47585236	47585259	X	-	27260156	TC32	viability	GTAGACGAACCGGATGTCAGCGG	SYN1	ENSG00000008056	0.11232540807230862	[0]	[0,0,0,0]	2	hSpCas9	negative selection	9455649
47584934	47584957	X	+	27260156	TC32	viability	AGTCATCAGGGCCAAGTTCGTGG	SYN1	ENSG00000008056	0.3175206015539287	[410]	[347,418,542,646]	5	hSpCas9	negative selection	9455650
47606980	47607003	X	+	27260156	TC32	viability	ATCCACAGAGAATCCACCATTGG	SYN1	ENSG00000008056	-0.1466323642494859	[685]	[548,399,614,823]	-3	hSpCas9	negative selection	9518324
47607181	47607204	X	-	27260156	TC32	viability	TCCAGGGCAAAATACTTCAAAGG	SYN1	ENSG00000008056	-0.10912825781608126	[161]	[99,82,168,242]	-2	hSpCas9	negative selection	9518325
47607140	47607163	X	-	27260156	TC32	viability	AATTGACATTAAAGTAGAACAGG	SYN1	ENSG00000008056	-0.07947407401299603	[504]	[383,368,550,525]	-1	hSpCas9	negative selection	9518326
47585294	47585317	X	+	27260156	TC32	viability	CAGGTCCCACAACCGCAGCGAGG	SYN1	ENSG00000008056	-0.12353945741839434	[221]	[173,79,275,290]	-2	hSpCas9	negative selection	9519901
47585629	47585652	X	+	27260156	TC32	viability	TTCACCAAGACCTACACTGTTGG	SYN1	ENSG00000008056	-0.6646215738421819	[220]	[73,147,143,153]	-8	hSpCas9	negative selection	9519902
47585603	47585626	X	+	27260156	TC32	viability	GCCTGAGCTTAGCTCAGCGCCGG	SYN1	ENSG00000008056	0.2507604067384609	[259]	[282,256,328,295]	4	hSpCas9	negative selection	9519903
47576154	47576177	X	-	27869803	HPAFII	viability after 27 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.5454626869958437	[192]	[188,113,NaN]	4	hSpCas9	negative selection	9608856
47576328	47576351	X	-	27869803	HPAFII	viability after 27 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-0.0951620073628403	[185]	[24,146,NaN]	0	hSpCas9	negative selection	9608857
47605034	47605057	X	-	27869803	HPAFII	viability after 27 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.854331472345065	[201]	[191,191,NaN]	7	hSpCas9	negative selection	9608858
47605320	47605343	X	-	27869803	HPAFII	viability after 27 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.4158530324555344	[466]	[236,402,NaN]	3	hSpCas9	negative selection	9608859
47606985	47607008	X	+	27869803	HPAFII	viability after 27 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	1.167064541772754	[509]	[918,337,NaN]	8	hSpCas9	negative selection	9608860
47619689	47619712	X	+	27869803	HPAFII	viability after 27 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	1.205981173722145	[207]	[176,314,NaN]	8	hSpCas9	negative selection	9608861
47576154	47576177	X	-	27869803	HPAFII	viability after 15 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	0.6073090954017439	[192]	[397,264,NaN]	7	hSpCas9	negative selection	9691305
47576328	47576351	X	-	27869803	HPAFII	viability after 15 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-1.164509952587884	[185]	[37,120,NaN]	-8	hSpCas9	negative selection	9691306
47605034	47605057	X	-	27869803	HPAFII	viability after 15 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.47222123889531553	[201]	[450,207,NaN]	5	hSpCas9	negative selection	9691307
47605320	47605343	X	-	27869803	HPAFII	viability after 15 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	-0.0009184333274776524	[466]	[635,417,NaN]	0	hSpCas9	negative selection	9691308
47606985	47607008	X	+	27869803	HPAFII	viability after 15 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.31649942672625286	[509]	[861,570,NaN]	3	hSpCas9	negative selection	9691309
47619689	47619712	X	+	27869803	HPAFII	viability after 15 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.558149439632595	[207]	[412,276,NaN]	6	hSpCas9	negative selection	9691310
47576154	47576177	X	-	27869803	ASPC1	viability after 36 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	-0.07696175888371326	[428]	[66,262,96]	-1	hSpCas9	negative selection	9773754
47576328	47576351	X	-	27869803	ASPC1	viability after 36 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.09715013344326623	[453]	[278,210,57]	0	hSpCas9	negative selection	9773755
47605034	47605057	X	-	27869803	ASPC1	viability after 36 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.4263482187753388	[577]	[400,60,343]	4	hSpCas9	negative selection	9773756
47605320	47605343	X	-	27869803	ASPC1	viability after 36 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.04120191123790201	[866]	[406,308,242]	0	hSpCas9	negative selection	9773757
47606985	47607008	X	+	27869803	ASPC1	viability after 36 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.5539428506955052	[1037]	[629,446,524]	5	hSpCas9	negative selection	9773758
47619689	47619712	X	+	27869803	ASPC1	viability after 36 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.8449721512235439	[574]	[188,439,413]	7	hSpCas9	negative selection	9773759
47576154	47576177	X	-	27869803	PATU8988S	viability after 35 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	-0.1403996056840654	[378]	[132,143,NaN]	-1	hSpCas9	negative selection	9856203
47576328	47576351	X	-	27869803	PATU8988S	viability after 35 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-0.6756577665794511	[376]	[119,69,NaN]	-6	hSpCas9	negative selection	9856204
47605034	47605057	X	-	27869803	PATU8988S	viability after 35 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.19041392961998935	[457]	[203,216,NaN]	2	hSpCas9	negative selection	9856205
47605320	47605343	X	-	27869803	PATU8988S	viability after 35 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.7383391076714151	[667]	[589,306,NaN]	7	hSpCas9	negative selection	9856206
47606985	47607008	X	+	27869803	PATU8988S	viability after 35 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.46674691191392303	[1031]	[533,614,NaN]	5	hSpCas9	negative selection	9856207
47619689	47619712	X	+	27869803	PATU8988S	viability after 35 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	-0.09417557561753458	[516]	[222,166,NaN]	-1	hSpCas9	negative selection	9856208
47576154	47576177	X	-	27869803	PATU8988S	viability after 31 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	-0.5247806236297613	[378]	[108,99,NaN]	-5	hSpCas9	negative selection	9938652
47576328	47576351	X	-	27869803	PATU8988S	viability after 31 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-0.05326326745004928	[376]	[132,159,NaN]	0	hSpCas9	negative selection	9938653
47605034	47605057	X	-	27869803	PATU8988S	viability after 31 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	0.09630390597144498	[457]	[152,248,NaN]	1	hSpCas9	negative selection	9938654
47605320	47605343	X	-	27869803	PATU8988S	viability after 31 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.43694046292032784	[667]	[459,233,NaN]	5	hSpCas9	negative selection	9938655
47606985	47607008	X	+	27869803	PATU8988S	viability after 31 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	0.20489392500976067	[1031]	[373,601,NaN]	2	hSpCas9	negative selection	9938656
47619689	47619712	X	+	27869803	PATU8988S	viability after 31 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	0.12750683298102666	[516]	[222,227,NaN]	1	hSpCas9	negative selection	9938657
47576154	47576177	X	-	27869803	HPAFII	viability after 35 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	1.0095977200653188	[192]	[215,174,NaN]	6	hSpCas9	negative selection	10021101
47576328	47576351	X	-	27869803	HPAFII	viability after 35 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	-0.08865951582506038	[185]	[9,176,NaN]	0	hSpCas9	negative selection	10021102
47605034	47605057	X	-	27869803	HPAFII	viability after 35 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	1.5832574959379173	[201]	[328,280,NaN]	9	hSpCas9	negative selection	10021103
47605320	47605343	X	-	27869803	HPAFII	viability after 35 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.4708311068427834	[466]	[218,449,NaN]	3	hSpCas9	negative selection	10021104
47606985	47607008	X	+	27869803	HPAFII	viability after 35 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	1.5390900242091892	[509]	[1032,431,NaN]	8	hSpCas9	negative selection	10021105
47619689	47619712	X	+	27869803	HPAFII	viability after 35 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	1.6130437812752392	[207]	[180,480,NaN]	9	hSpCas9	negative selection	10021106
47576154	47576177	X	-	27869803	HPAFII	viability after 31 days	AGTGGAAGCGCTACATGGCAAGG	SYN1	ENSG00000008056	1.036907403947066	[192]	[249,191,NaN]	7	hSpCas9	negative selection	10103550
47576328	47576351	X	-	27869803	HPAFII	viability after 31 days	AAATTGCCATGTCTGACAGGTGG	SYN1	ENSG00000008056	0.2157983349129962	[185]	[36,212,NaN]	1	hSpCas9	negative selection	10103551
47605034	47605057	X	-	27869803	HPAFII	viability after 31 days	GGTTCGACTGCATAAGAAACTGG	SYN1	ENSG00000008056	1.2262132494368292	[201]	[325,198,NaN]	8	hSpCas9	negative selection	10103552
47605320	47605343	X	-	27869803	HPAFII	viability after 31 days	GCCTTCAGCATGGCACGCAACGG	SYN1	ENSG00000008056	0.4744531959301935	[466]	[210,530,NaN]	3	hSpCas9	negative selection	10103553
47606985	47607008	X	+	27869803	HPAFII	viability after 31 days	CAGAGAATCCACCATTGGCATGG	SYN1	ENSG00000008056	1.2244025748469332	[509]	[875,442,NaN]	8	hSpCas9	negative selection	10103554
47619689	47619712	X	+	27869803	HPAFII	viability after 31 days	TAAAGTTGCTGTCCGACAGGCGG	SYN1	ENSG00000008056	1.650994457186689	[207]	[245,497,NaN]	9	hSpCas9	negative selection	10103555
47619375	47619398	X	+	28162770	P31FUJ	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-0.8177647051355348	[92]	[61]	-6	hSpCas9	negative selection	10246012
47576150	47576173	X	-	28162770	P31FUJ	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	0.3694797725068038	[275]	[418]	4	hSpCas9	negative selection	10246013
47619564	47619587	X	+	28162770	P31FUJ	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	0.08677813561656086	[245]	[306]	0	hSpCas9	negative selection	10246014
47619458	47619481	X	-	28162770	P31FUJ	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.5492927652414873	[106]	[183]	6	hSpCas9	negative selection	10246015
47605291	47605314	X	+	28162770	P31FUJ	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.9895902169220692	[110]	[258]	9	hSpCas9	negative selection	10246016
47605226	47605249	X	-	28162770	P31FUJ	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	0.27243310383604363	[185]	[263]	3	hSpCas9	negative selection	10246017
47577477	47577500	X	-	28162770	P31FUJ	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.09301980657747466	[295]	[370]	0	hSpCas9	negative selection	10246018
47577444	47577467	X	-	28162770	P31FUJ	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	0.24700555025470317	[146]	[204]	2	hSpCas9	negative selection	10246019
47576221	47576244	X	-	28162770	P31FUJ	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.6307968282828449	[326]	[594]	7	hSpCas9	negative selection	10246020
47576172	47576195	X	-	28162770	P31FUJ	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	0.5752110316135297	[312]	[547]	6	hSpCas9	negative selection	10246021
47619375	47619398	X	+	28162770	TF1	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10415378
47576150	47576173	X	-	28162770	TF1	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	NaN	[NaN]	[271]	1	hSpCas9	negative selection	10415379
47619564	47619587	X	+	28162770	TF1	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	NaN	[NaN]	[316]	1	hSpCas9	negative selection	10415380
47619458	47619481	X	-	28162770	TF1	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10415381
47605291	47605314	X	+	28162770	TF1	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10415382
47605226	47605249	X	-	28162770	TF1	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	NaN	[NaN]	[148]	1	hSpCas9	negative selection	10415383
47577477	47577500	X	-	28162770	TF1	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	NaN	[NaN]	[205]	1	hSpCas9	negative selection	10415384
47577444	47577467	X	-	28162770	TF1	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	NaN	[NaN]	[210]	1	hSpCas9	negative selection	10415385
47576221	47576244	X	-	28162770	TF1	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	NaN	[NaN]	[449]	1	hSpCas9	negative selection	10415386
47576172	47576195	X	-	28162770	TF1	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	NaN	[NaN]	[330]	1	hSpCas9	negative selection	10415387
47619375	47619398	X	+	28162770	SKM1	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-0.18457177740671393	[17]	[27]	-1	hSpCas9	negative selection	10584744
47576150	47576173	X	-	28162770	SKM1	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	-0.07102924586191994	[81]	[137]	0	hSpCas9	negative selection	10584745
47619564	47619587	X	+	28162770	SKM1	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	0.4905885322860206	[61]	[153]	5	hSpCas9	negative selection	10584746
47619458	47619481	X	-	28162770	SKM1	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.08178298671869133	[30]	[57]	0	hSpCas9	negative selection	10584747
47605291	47605314	X	+	28162770	SKM1	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.864498829161213	[31]	[102]	7	hSpCas9	negative selection	10584748
47605226	47605249	X	-	28162770	SKM1	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	0.9458248598489611	[36]	[125]	8	hSpCas9	negative selection	10584749
47577477	47577500	X	-	28162770	SKM1	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.13882770469731673	[55]	[108]	1	hSpCas9	negative selection	10584750
47577444	47577467	X	-	28162770	SKM1	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	-0.11150831521699056	[32]	[53]	-1	hSpCas9	negative selection	10584751
47576221	47576244	X	-	28162770	SKM1	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.1671915470214117	[66]	[132]	1	hSpCas9	negative selection	10584752
47576172	47576195	X	-	28162770	SKM1	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	0.057704068260282904	[74]	[137]	0	hSpCas9	negative selection	10584753
47619375	47619398	X	+	28162770	SKM1	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-0.18457177740671393	[17]	[27]	-1	hSpCas9	negative selection	10754110
47576150	47576173	X	-	28162770	SKM1	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	-0.07102924586191994	[81]	[137]	0	hSpCas9	negative selection	10754111
47619564	47619587	X	+	28162770	SKM1	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	0.4905885322860206	[61]	[153]	5	hSpCas9	negative selection	10754112
47619458	47619481	X	-	28162770	SKM1	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.08178298671869133	[30]	[57]	0	hSpCas9	negative selection	10754113
47605291	47605314	X	+	28162770	SKM1	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.864498829161213	[31]	[102]	7	hSpCas9	negative selection	10754114
47605226	47605249	X	-	28162770	SKM1	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	0.9458248598489611	[36]	[125]	8	hSpCas9	negative selection	10754115
47577477	47577500	X	-	28162770	SKM1	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.13882770469731673	[55]	[108]	1	hSpCas9	negative selection	10754116
47577444	47577467	X	-	28162770	SKM1	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	-0.11150831521699056	[32]	[53]	-1	hSpCas9	negative selection	10754117
47576221	47576244	X	-	28162770	SKM1	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.1671915470214117	[66]	[132]	1	hSpCas9	negative selection	10754118
47576172	47576195	X	-	28162770	SKM1	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	0.057704068260282904	[74]	[137]	0	hSpCas9	negative selection	10754119
47619375	47619398	X	+	28162770	PL21	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-0.31443355834043807	[79]	[27]	-2	hSpCas9	negative selection	10923476
47576150	47576173	X	-	28162770	PL21	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	0.5195994537859328	[233]	[145]	4	hSpCas9	negative selection	10923477
47619564	47619587	X	+	28162770	PL21	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	-0.14020051751192247	[275]	[108]	-1	hSpCas9	negative selection	10923478
47619458	47619481	X	-	28162770	PL21	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	-0.49729761549024865	[119]	[36]	-4	hSpCas9	negative selection	10923479
47605291	47605314	X	+	28162770	PL21	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.8945133319310582	[109]	[88]	7	hSpCas9	negative selection	10923480
47605226	47605249	X	-	28162770	PL21	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	0.3636383467721996	[149]	[83]	3	hSpCas9	negative selection	10923481
47577477	47577500	X	-	28162770	PL21	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.9806944772032091	[162]	[139]	7	hSpCas9	negative selection	10923482
47577444	47577467	X	-	28162770	PL21	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	-1.0652049520316746	[124]	[25]	-6	hSpCas9	negative selection	10923483
47576221	47576244	X	-	28162770	PL21	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.8488780256437913	[235]	[184]	7	hSpCas9	negative selection	10923484
47576172	47576195	X	-	28162770	PL21	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	1.1849798073183144	[286]	[283]	8	hSpCas9	negative selection	10923485
47619375	47619398	X	+	28162770	P31FUJ	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-0.8177647051355348	[92]	[61]	-6	hSpCas9	negative selection	11092842
47576150	47576173	X	-	28162770	P31FUJ	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	0.3694797725068038	[275]	[418]	4	hSpCas9	negative selection	11092843
47619564	47619587	X	+	28162770	P31FUJ	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	0.08677813561656086	[245]	[306]	0	hSpCas9	negative selection	11092844
47619458	47619481	X	-	28162770	P31FUJ	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.5492927652414873	[106]	[183]	6	hSpCas9	negative selection	11092845
47605291	47605314	X	+	28162770	P31FUJ	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.9895902169220692	[110]	[258]	9	hSpCas9	negative selection	11092846
47605226	47605249	X	-	28162770	P31FUJ	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	0.27243310383604363	[185]	[263]	3	hSpCas9	negative selection	11092847
47577477	47577500	X	-	28162770	P31FUJ	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.09301980657747466	[295]	[370]	0	hSpCas9	negative selection	11092848
47577444	47577467	X	-	28162770	P31FUJ	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	0.24700555025470317	[146]	[204]	2	hSpCas9	negative selection	11092849
47576221	47576244	X	-	28162770	P31FUJ	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.6307968282828449	[326]	[594]	7	hSpCas9	negative selection	11092850
47576172	47576195	X	-	28162770	P31FUJ	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	0.5752110316135297	[312]	[547]	6	hSpCas9	negative selection	11092851
47619375	47619398	X	+	28162770	OCIAML5	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	0.5147157598076257	[37]	[97]	4	hSpCas9	negative selection	11262208
47576150	47576173	X	-	28162770	OCIAML5	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	1.4033841390517465	[150]	[720]	9	hSpCas9	negative selection	11262209
47619564	47619587	X	+	28162770	OCIAML5	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	-0.03566650920338571	[158]	[279]	0	hSpCas9	negative selection	11262210
47619458	47619481	X	-	28162770	OCIAML5	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	1.2120637665557188	[32]	[137]	8	hSpCas9	negative selection	11262211
47605291	47605314	X	+	28162770	OCIAML5	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.41739410412922995	[55]	[134]	3	hSpCas9	negative selection	11262212
47605226	47605249	X	-	28162770	OCIAML5	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	0.5745589026900587	[92]	[249]	5	hSpCas9	negative selection	11262213
47577477	47577500	X	-	28162770	OCIAML5	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	1.1512085611688638	[109]	[440]	8	hSpCas9	negative selection	11262214
47577444	47577467	X	-	28162770	OCIAML5	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	1.0283518133833307	[65]	[242]	8	hSpCas9	negative selection	11262215
47576221	47576244	X	-	28162770	OCIAML5	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.39387184114648943	[190]	[452]	3	hSpCas9	negative selection	11262216
47576172	47576195	X	-	28162770	OCIAML5	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	0.508250353227675	[177]	[456]	4	hSpCas9	negative selection	11262217
47619375	47619398	X	+	28162770	EOL1	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-0.4045758247210316	[200]	[79]	-3	hSpCas9	negative selection	11431574
47576150	47576173	X	-	28162770	EOL1	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	0.6169749696602422	[249]	[201]	5	hSpCas9	negative selection	11431575
47619564	47619587	X	+	28162770	EOL1	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	0.2679728016885395	[412]	[261]	2	hSpCas9	negative selection	11431576
47619458	47619481	X	-	28162770	EOL1	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.8648415254462668	[147]	[141]	7	hSpCas9	negative selection	11431577
47605291	47605314	X	+	28162770	EOL1	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.5240098419868058	[230]	[174]	5	hSpCas9	negative selection	11431578
47605226	47605249	X	-	28162770	EOL1	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	-0.20268741672557328	[307]	[140]	-1	hSpCas9	negative selection	11431579
47577477	47577500	X	-	28162770	EOL1	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	-0.2192880010031169	[273]	[123]	-2	hSpCas9	negative selection	11431580
47577444	47577467	X	-	28162770	EOL1	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	-0.29268294465013445	[92]	[39]	-2	hSpCas9	negative selection	11431581
47576221	47576244	X	-	28162770	EOL1	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	-0.12068148242246314	[323]	[156]	-1	hSpCas9	negative selection	11431582
47576172	47576195	X	-	28162770	EOL1	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	1.6711635357704602	[297]	[499]	9	hSpCas9	negative selection	11431583
47619375	47619398	X	+	28162770	MOLM13	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-2.582736691525389	[173]	[20]	-8	hSpCas9	negative selection	11600940
47576150	47576173	X	-	28162770	MOLM13	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	0.5367844627556463	[367]	[385]	4	hSpCas9	negative selection	11600941
47619564	47619587	X	+	28162770	MOLM13	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	1.331418936994455	[348]	[634]	8	hSpCas9	negative selection	11600942
47619458	47619481	X	-	28162770	MOLM13	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	-0.3428402672936819	[106]	[60]	-2	hSpCas9	negative selection	11600943
47605291	47605314	X	+	28162770	MOLM13	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	1.1327051899549496	[122]	[194]	8	hSpCas9	negative selection	11600944
47605226	47605249	X	-	28162770	MOLM13	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	0.3354390855209293	[284]	[259]	2	hSpCas9	negative selection	11600945
47577477	47577500	X	-	28162770	MOLM13	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.7452790803554427	[249]	[302]	5	hSpCas9	negative selection	11600946
47577444	47577467	X	-	28162770	MOLM13	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	-0.6732029376900208	[160]	[72]	-4	hSpCas9	negative selection	11600947
47576221	47576244	X	-	28162770	MOLM13	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.7630726211994125	[391]	[480]	6	hSpCas9	negative selection	11600948
47576172	47576195	X	-	28162770	MOLM13	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	-0.8122185376481563	[458]	[188]	-4	hSpCas9	negative selection	11600949
47619375	47619398	X	+	28162770	HEL	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-0.2697983267493037	[127]	[67]	-2	hSpCas9	negative selection	11770306
47576150	47576173	X	-	28162770	HEL	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	0.20663971719368346	[367]	[271]	1	hSpCas9	negative selection	11770307
47619564	47619587	X	+	28162770	HEL	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	-0.3572611679996431	[351]	[175]	-3	hSpCas9	negative selection	11770308
47619458	47619481	X	-	28162770	HEL	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	-0.9331214616135468	[157]	[52]	-5	hSpCas9	negative selection	11770309
47605291	47605314	X	+	28162770	HEL	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	1.4848591722186377	[163]	[293]	9	hSpCas9	negative selection	11770310
47605226	47605249	X	-	28162770	HEL	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	1.2745461961811806	[201]	[312]	9	hSpCas9	negative selection	11770311
47577477	47577500	X	-	28162770	HEL	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	-0.015472650751437778	[201]	[127]	0	hSpCas9	negative selection	11770312
47577444	47577467	X	-	28162770	HEL	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	0.3894524027181253	[117]	[98]	3	hSpCas9	negative selection	11770313
47576221	47576244	X	-	28162770	HEL	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.36820045404811264	[276]	[228]	3	hSpCas9	negative selection	11770314
47576172	47576195	X	-	28162770	HEL	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	0.9717738133819795	[323]	[406]	8	hSpCas9	negative selection	11770315
47619375	47619398	X	+	28162770	MV411	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-1.0957070300142828	[136]	[53]	-6	hSpCas9	negative selection	11939672
47576150	47576173	X	-	28162770	MV411	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	0.07888328107387754	[262]	[233]	0	hSpCas9	negative selection	11939673
47619564	47619587	X	+	28162770	MV411	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	-0.18982989587953386	[217]	[160]	-1	hSpCas9	negative selection	11939674
47619458	47619481	X	-	28162770	MV411	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	1.421085638267805	[42]	[96]	9	hSpCas9	negative selection	11939675
47605291	47605314	X	+	28162770	MV411	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	-0.19024868744126888	[106]	[78]	-1	hSpCas9	negative selection	11939676
47605226	47605249	X	-	28162770	MV411	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	-0.19113546295685777	[205]	[151]	-1	hSpCas9	negative selection	11939677
47577477	47577500	X	-	28162770	MV411	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.07019716583870247	[172]	[152]	0	hSpCas9	negative selection	11939678
47577444	47577467	X	-	28162770	MV411	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	0.9236491138698851	[96]	[154]	8	hSpCas9	negative selection	11939679
47576221	47576244	X	-	28162770	MV411	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.4971576033356886	[253]	[301]	4	hSpCas9	negative selection	11939680
47576172	47576195	X	-	28162770	MV411	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	0.36637862350628275	[255]	[277]	3	hSpCas9	negative selection	11939681
47619375	47619398	X	+	28162770	MONOMAC1	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	-0.111645355828909	[81]	[86]	-1	hSpCas9	negative selection	12109038
47576150	47576173	X	-	28162770	MONOMAC1	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	1.2928358851418802	[161]	[454]	9	hSpCas9	negative selection	12109039
47619564	47619587	X	+	28162770	MONOMAC1	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	-0.11509523352337739	[153]	[162]	-1	hSpCas9	negative selection	12109040
47619458	47619481	X	-	28162770	MONOMAC1	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.17600656355466304	[60]	[78]	1	hSpCas9	negative selection	12109041
47605291	47605314	X	+	28162770	MONOMAC1	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	0.9802676847483563	[64]	[146]	8	hSpCas9	negative selection	12109042
47605226	47605249	X	-	28162770	MONOMAC1	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	0.8568300249191823	[91]	[190]	7	hSpCas9	negative selection	12109043
47577477	47577500	X	-	28162770	MONOMAC1	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	1.5186875995324824	[129]	[426]	9	hSpCas9	negative selection	12109044
47577444	47577467	X	-	28162770	MONOMAC1	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	1.9705631014365146	[68]	[309]	9	hSpCas9	negative selection	12109045
47576221	47576244	X	-	28162770	MONOMAC1	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	0.14661601898252474	[144]	[183]	1	hSpCas9	negative selection	12109046
47576172	47576195	X	-	28162770	MONOMAC1	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	-0.8528828339372198	[218]	[138]	-6	hSpCas9	negative selection	12109047
47619375	47619398	X	+	28162770	OCIAML2	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	0.18144687133753168	[13]	[87]	1	hSpCas9	negative selection	12278404
47576150	47576173	X	-	28162770	OCIAML2	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	-0.07831240246340088	[47]	[251]	0	hSpCas9	negative selection	12278405
47619564	47619587	X	+	28162770	OCIAML2	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	1.0187550154967637	[38]	[437]	8	hSpCas9	negative selection	12278406
47619458	47619481	X	-	28162770	OCIAML2	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	0.19774868366663223	[13]	[88]	2	hSpCas9	negative selection	12278407
47605291	47605314	X	+	28162770	OCIAML2	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	1.0343643707755799	[16]	[192]	8	hSpCas9	negative selection	12278408
47605226	47605249	X	-	28162770	OCIAML2	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	-0.4200037521721931	[41]	[173]	-3	hSpCas9	negative selection	12278409
47577477	47577500	X	-	28162770	OCIAML2	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	0.2735312703282491	[29]	[200]	2	hSpCas9	negative selection	12278410
47577444	47577467	X	-	28162770	OCIAML2	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	0.5675053036446097	[13]	[114]	5	hSpCas9	negative selection	12278411
47576221	47576244	X	-	28162770	OCIAML2	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	1.25872258481417	[37]	[503]	9	hSpCas9	negative selection	12278412
47576172	47576195	X	-	28162770	OCIAML2	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	0.15180738089765783	[37]	[233]	1	hSpCas9	negative selection	12278413
47619375	47619398	X	+	28162770	OCIAML3	viability	GACCAGCAGCACCCTGGAGGCGG	SYN1	ENSG00000008056	0.7983097824545972	[35]	[188]	7	hSpCas9	negative selection	12447770
47576150	47576173	X	-	28162770	OCIAML3	viability	GAAGCGCTACATGGCAAGGACGG	SYN1	ENSG00000008056	-0.18461670418646134	[63]	[169]	-1	hSpCas9	negative selection	12447771
47619564	47619587	X	+	28162770	OCIAML3	viability	GGAGGACCTCTCGGCAGTGGCGG	SYN1	ENSG00000008056	-0.18114451227965633	[82]	[220]	-1	hSpCas9	negative selection	12447772
47619458	47619481	X	-	28162770	OCIAML3	viability	GGTCAAGCAGACCACGGCGGCGG	SYN1	ENSG00000008056	1.2804614775919778	[14]	[109]	9	hSpCas9	negative selection	12447773
47605291	47605314	X	+	28162770	OCIAML3	viability	GCAGCCCAATGACCAAACTGCGG	SYN1	ENSG00000008056	-0.054848829216131656	[31]	[92]	0	hSpCas9	negative selection	12447774
47605226	47605249	X	-	28162770	OCIAML3	viability	ACAACTTCTGTGACAAGCCCTGG	SYN1	ENSG00000008056	-0.36206091227446646	[42]	[100]	-3	hSpCas9	negative selection	12447775
47577477	47577500	X	-	28162770	OCIAML3	viability	CAGCAGTACAACGTACCCCGTGG	SYN1	ENSG00000008056	-0.1738991514978973	[70]	[189]	-1	hSpCas9	negative selection	12447776
47577444	47577467	X	-	28162770	OCIAML3	viability	GGGGCACGCACACTCTGGGATGG	SYN1	ENSG00000008056	-0.12193919600894043	[30]	[85]	-1	hSpCas9	negative selection	12447777
47576221	47576244	X	-	28162770	OCIAML3	viability	GTCTTGGCAGATACAAGCTGTGG	SYN1	ENSG00000008056	1.491095928052254	[71]	[610]	9	hSpCas9	negative selection	12447778
47576172	47576195	X	-	28162770	OCIAML3	viability	GGGACTGGACATCTGCGCAGTGG	SYN1	ENSG00000008056	-0.03848891749548894	[65]	[193]	0	hSpCas9	negative selection	12447779