| 12141967 | 12141990 | 3 | + | 26627737 | DLD1 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.09265942426603163 | [353] | [83,219,62] | 0 | hSpCas9 | negative selection | 819070 | 12145675 | 12145698 | 3 | - | 26627737 | DLD1 | viability | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 1.1688008064400552 | [137] | [126,73,89] | 9 | hSpCas9 | negative selection | 819071 | 12151242 | 12151265 | 3 | - | 26627737 | DLD1 | viability | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 0.26314626638328 | [132] | [61,53,35] | 2 | hSpCas9 | negative selection | 819072 | 12161564 | 12161587 | 3 | - | 26627737 | DLD1 | viability | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.3097427221209563 | [858] | [315,348,333] | 3 | hSpCas9 | negative selection | 819085 | 12162116 | 12162139 | 3 | - | 26627737 | DLD1 | viability | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.39320176330635304 | [917] | [447,201,459] | 4 | hSpCas9 | negative selection | 819086 | 12141967 | 12141990 | 3 | + | 26627737 | GBM cells | viability after 5 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.1762518187489775 | [183] | [150,71] | 3 | hSpCas9 | negative selection | 901385 | 12145675 | 12145698 | 3 | - | 26627737 | GBM cells | viability after 5 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | -0.5117184452731571 | [108] | [41,39] | -7 | hSpCas9 | negative selection | 901386 | 12151242 | 12151265 | 3 | - | 26627737 | GBM cells | viability after 5 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 0.5869698685709452 | [71] | [56,58] | 8 | hSpCas9 | negative selection | 901387 | 12161564 | 12161587 | 3 | - | 26627737 | GBM cells | viability after 5 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.6426413597607845 | [297] | [243,254] | 8 | hSpCas9 | negative selection | 901400 | 12162116 | 12162139 | 3 | - | 26627737 | GBM cells | viability after 5 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.096485124136095 | [401] | [232,227] | 1 | hSpCas9 | negative selection | 901401 | 12141967 | 12141990 | 3 | + | 26627737 | GBM cells | viability after 13 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.24196098733925298 | [183] | [95,74] | -3 | hSpCas9 | negative selection | 983700 | 12145675 | 12145698 | 3 | - | 26627737 | GBM cells | viability after 13 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.37089057947517123 | [108] | [65,84] | 5 | hSpCas9 | negative selection | 983701 | 12151242 | 12151265 | 3 | - | 26627737 | GBM cells | viability after 13 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 0.6062825627888102 | [71] | [32,80] | 7 | hSpCas9 | negative selection | 983702 | 12161564 | 12161587 | 3 | - | 26627737 | GBM cells | viability after 13 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.42355672085101853 | [297] | [212,219] | 5 | hSpCas9 | negative selection | 983715 | 12162116 | 12162139 | 3 | - | 26627737 | GBM cells | viability after 13 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.3624545012188546 | [401] | [350,222] | 4 | hSpCas9 | negative selection | 983716 | 12141967 | 12141990 | 3 | + | 26627737 | GBM cells | viability after 21 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.01535888473445618 | [183] | [111,90] | 0 | hSpCas9 | negative selection | 1066015 | 12145675 | 12145698 | 3 | - | 26627737 | GBM cells | viability after 21 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.2554605350485709 | [108] | [77,63] | 2 | hSpCas9 | negative selection | 1066016 | 12151242 | 12151265 | 3 | - | 26627737 | GBM cells | viability after 21 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 1.5881888507386228 | [71] | [114,119] | 9 | hSpCas9 | negative selection | 1066017 | 12161564 | 12161587 | 3 | - | 26627737 | GBM cells | viability after 21 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.22194953237364207 | [297] | [192,184] | 2 | hSpCas9 | negative selection | 1066030 | 12162116 | 12162139 | 3 | - | 26627737 | GBM cells | viability after 21 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.5342806736163711 | [401] | [332,300] | 5 | hSpCas9 | negative selection | 1066031 | 12141967 | 12141990 | 3 | + | 26627737 | RPE1 | viability after 9 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.11274008151430953 | [606] | [163,258] | 0 | hSpCas9 | negative selection | 1148330 | 12145675 | 12145698 | 3 | - | 26627737 | RPE1 | viability after 9 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 1.2477002748577604 | [234] | [244,83] | 7 | hSpCas9 | negative selection | 1148331 | 12151242 | 12151265 | 3 | - | 26627737 | RPE1 | viability after 9 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | -0.024668974549304723 | [328] | [102,98] | 0 | hSpCas9 | negative selection | 1148332 | 12161564 | 12161587 | 3 | - | 26627737 | RPE1 | viability after 9 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 1.4802920768798513 | [586] | [534,483] | 8 | hSpCas9 | negative selection | 1148345 | 12162116 | 12162139 | 3 | - | 26627737 | RPE1 | viability after 9 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 1.5610813137446402 | [926] | [906,790] | 8 | hSpCas9 | negative selection | 1148346 | 12141967 | 12141990 | 3 | + | 26627737 | RPE1 | viability after 12 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.26547883960531804 | [606] | [179,212] | 1 | hSpCas9 | negative selection | 1230645 | 12145675 | 12145698 | 3 | - | 26627737 | RPE1 | viability after 12 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 1.045445903020926 | [234] | [208,46] | 6 | hSpCas9 | negative selection | 1230646 | 12151242 | 12151265 | 3 | - | 26627737 | RPE1 | viability after 12 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 0.015448124917970096 | [328] | [100,76] | 0 | hSpCas9 | negative selection | 1230647 | 12161564 | 12161587 | 3 | - | 26627737 | RPE1 | viability after 12 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 1.4177455762978708 | [586] | [483,354] | 7 | hSpCas9 | negative selection | 1230660 | 12162116 | 12162139 | 3 | - | 26627737 | RPE1 | viability after 12 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 1.2670611566738192 | [926] | [578,620] | 7 | hSpCas9 | negative selection | 1230661 | 12141967 | 12141990 | 3 | + | 26627737 | RPE1 | viability after 15 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.4090432335636672 | [606] | [143,308] | 2 | hSpCas9 | negative selection | 1312960 | 12145675 | 12145698 | 3 | - | 26627737 | RPE1 | viability after 15 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 1.3743025235994972 | [234] | [265,81] | 7 | hSpCas9 | negative selection | 1312961 | 12151242 | 12151265 | 3 | - | 26627737 | RPE1 | viability after 15 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 0.17224651001562452 | [328] | [55,151] | 1 | hSpCas9 | negative selection | 1312962 | 12161564 | 12161587 | 3 | - | 26627737 | RPE1 | viability after 15 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 1.9284110526631424 | [586] | [713,552] | 8 | hSpCas9 | negative selection | 1312975 | 12162116 | 12162139 | 3 | - | 26627737 | RPE1 | viability after 15 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 1.4057368876156777 | [926] | [678,709] | 7 | hSpCas9 | negative selection | 1312976 | 12141967 | 12141990 | 3 | + | 26627737 | RPE1 | viability after 18 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.08594902863846177 | [606] | [134,174] | 0 | hSpCas9 | negative selection | 1395275 | 12145675 | 12145698 | 3 | - | 26627737 | RPE1 | viability after 18 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.7594666274318493 | [234] | [146,64] | 4 | hSpCas9 | negative selection | 1395276 | 12151242 | 12151265 | 3 | - | 26627737 | RPE1 | viability after 18 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | -0.023449700899371928 | [328] | [53,122] | 0 | hSpCas9 | negative selection | 1395277 | 12161564 | 12161587 | 3 | - | 26627737 | RPE1 | viability after 18 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 1.0801422521582174 | [586] | [288,383] | 6 | hSpCas9 | negative selection | 1395290 | 12162116 | 12162139 | 3 | - | 26627737 | RPE1 | viability after 18 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 1.5664155914288749 | [926] | [621,867] | 8 | hSpCas9 | negative selection | 1395291 | 12141967 | 12141990 | 3 | + | 26627737 | HeLa | viability after 8 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.20592438386222428 | [408] | [163,175,126] | -2 | hSpCas9 | negative selection | 1477590 | 12145675 | 12145698 | 3 | - | 26627737 | HeLa | viability after 8 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 1.6922138896382095 | [94] | [174,43,186] | 9 | hSpCas9 | negative selection | 1477591 | 12151242 | 12151265 | 3 | - | 26627737 | HeLa | viability after 8 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 1.3926634738769064 | [43] | [49,68,32] | 8 | hSpCas9 | negative selection | 1477592 | 12161564 | 12161587 | 3 | - | 26627737 | HeLa | viability after 8 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | -0.8286399414141188 | [881] | [318,284,76] | -7 | hSpCas9 | negative selection | 1477605 | 12162116 | 12162139 | 3 | - | 26627737 | HeLa | viability after 8 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 1.356119371346211 | [372] | [369,369,490] | 8 | hSpCas9 | negative selection | 1477606 | 12141967 | 12141990 | 3 | + | 26627737 | HeLa | viability after 12 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.28566326363473094 | [408] | [145,149,118] | -3 | hSpCas9 | negative selection | 1559905 | 12145675 | 12145698 | 3 | - | 26627737 | HeLa | viability after 12 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.4365947026405994 | [94] | [9,63,82] | 4 | hSpCas9 | negative selection | 1559906 | 12151242 | 12151265 | 3 | - | 26627737 | HeLa | viability after 12 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 1.8864363933434973 | [43] | [119,40,44] | 9 | hSpCas9 | negative selection | 1559907 | 12161564 | 12161587 | 3 | - | 26627737 | HeLa | viability after 12 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | -0.7222565969601046 | [881] | [123,220,314] | -6 | hSpCas9 | negative selection | 1559920 | 12162116 | 12162139 | 3 | - | 26627737 | HeLa | viability after 12 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 1.6220385917486908 | [372] | [603,400,429] | 9 | hSpCas9 | negative selection | 1559921 | 12141967 | 12141990 | 3 | + | 26627737 | HeLa | viability after 15 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.5507090088057591 | [408] | [121,91,127] | -5 | hSpCas9 | negative selection | 1642220 | 12145675 | 12145698 | 3 | - | 26627737 | HeLa | viability after 15 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.9169757849360209 | [94] | [15,55,153] | 7 | hSpCas9 | negative selection | 1642221 | 12151242 | 12151265 | 3 | - | 26627737 | HeLa | viability after 15 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 2.7507407099075336 | [43] | [170,81,106] | 9 | hSpCas9 | negative selection | 1642222 | 12161564 | 12161587 | 3 | - | 26627737 | HeLa | viability after 15 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | -1.0163206898689254 | [881] | [99,177,261] | -7 | hSpCas9 | negative selection | 1642235 | 12162116 | 12162139 | 3 | - | 26627737 | HeLa | viability after 15 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 1.4074035749769753 | [372] | [292,414,509] | 8 | hSpCas9 | negative selection | 1642236 | 12141967 | 12141990 | 3 | + | 26627737 | HeLa | viability after 18 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.5572535406509431 | [408] | [80,75,127] | -5 | hSpCas9 | negative selection | 1724535 | 12145675 | 12145698 | 3 | - | 26627737 | HeLa | viability after 18 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.8858571668902679 | [94] | [7,45,153] | 6 | hSpCas9 | negative selection | 1724536 | 12151242 | 12151265 | 3 | - | 26627737 | HeLa | viability after 18 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 2.7748143385133504 | [43] | [116,69,106] | 9 | hSpCas9 | negative selection | 1724537 | 12161564 | 12161587 | 3 | - | 26627737 | HeLa | viability after 18 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | -1.012180187644755 | [881] | [65,149,261] | -7 | hSpCas9 | negative selection | 1724550 | 12162116 | 12162139 | 3 | - | 26627737 | HeLa | viability after 18 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 1.4035352256352007 | [372] | [194,342,509] | 8 | hSpCas9 | negative selection | 1724551 | 12141967 | 12141990 | 3 | + | 26627737 | HCT116 | viability after 6 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.9011191202375647 | [375] | [43,146] | 5 | hSpCas9 | negative selection | 1806850 | 12145675 | 12145698 | 3 | - | 26627737 | HCT116 | viability after 6 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | -0.6998051042062057 | [229] | [58,1] | -4 | hSpCas9 | negative selection | 1806851 | 12151242 | 12151265 | 3 | - | 26627737 | HCT116 | viability after 6 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 2.594758428291108 | [162] | [41,216] | 9 | hSpCas9 | negative selection | 1806852 | 12161564 | 12161587 | 3 | - | 26627737 | HCT116 | viability after 6 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.3444529444989078 | [560] | [256,31] | 2 | hSpCas9 | negative selection | 1806865 | 12162116 | 12162139 | 3 | - | 26627737 | HCT116 | viability after 6 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.793126121223589 | [955] | [233,274] | 4 | hSpCas9 | negative selection | 1806866 | 12141967 | 12141990 | 3 | + | 26627737 | HCT116 | viability after 8 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.444728677580407 | [171] | [164,123,98] | 4 | hSpCas9 | negative selection | 1889165 | 12145675 | 12145698 | 3 | - | 26627737 | HCT116 | viability after 8 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.8005526000705225 | [134] | [106,126,153] | 7 | hSpCas9 | negative selection | 1889166 | 12151242 | 12151265 | 3 | - | 26627737 | HCT116 | viability after 8 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 0.6099177141297518 | [62] | [24,43,88] | 6 | hSpCas9 | negative selection | 1889167 | 12161564 | 12161587 | 3 | - | 26627737 | HCT116 | viability after 8 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.3136177890514855 | [477] | [454,257,271] | 3 | hSpCas9 | negative selection | 1889180 | 12162116 | 12162139 | 3 | - | 26627737 | HCT116 | viability after 8 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.3930421115353864 | [625] | [571,416,372] | 4 | hSpCas9 | negative selection | 1889181 | 12141967 | 12141990 | 3 | + | 26627737 | HCT116 | viability after 9 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.20445503038711155 | [375] | [132,101] | 1 | hSpCas9 | negative selection | 1971480 | 12145675 | 12145698 | 3 | - | 26627737 | HCT116 | viability after 9 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.47909938546983144 | [229] | [55,108] | 3 | hSpCas9 | negative selection | 1971481 | 12151242 | 12151265 | 3 | - | 26627737 | HCT116 | viability after 9 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | -1.1781338547198619 | [162] | [16,20] | -7 | hSpCas9 | negative selection | 1971482 | 12161564 | 12161587 | 3 | - | 26627737 | HCT116 | viability after 9 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.5728666066085286 | [560] | [338,130] | 4 | hSpCas9 | negative selection | 1971495 | 12162116 | 12162139 | 3 | - | 26627737 | HCT116 | viability after 9 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 1.1460690237793787 | [955] | [617,522] | 7 | hSpCas9 | negative selection | 1971496 | 12141967 | 12141990 | 3 | + | 26627737 | HCT116 | viability after 12 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.5351045772316438 | [171] | [136,113,140] | 5 | hSpCas9 | negative selection | 2053795 | 12145675 | 12145698 | 3 | - | 26627737 | HCT116 | viability after 12 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.4347394951645571 | [134] | [75,77,134] | 4 | hSpCas9 | negative selection | 2053796 | 12151242 | 12151265 | 3 | - | 26627737 | HCT116 | viability after 12 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 0.6821778403317682 | [62] | [23,55,81] | 6 | hSpCas9 | negative selection | 2053797 | 12161564 | 12161587 | 3 | - | 26627737 | HCT116 | viability after 12 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.1283129294433336 | [477] | [327,232,256] | 1 | hSpCas9 | negative selection | 2053810 | 12162116 | 12162139 | 3 | - | 26627737 | HCT116 | viability after 12 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.49479457662726034 | [625] | [472,426,488] | 5 | hSpCas9 | negative selection | 2053811 | 12141967 | 12141990 | 3 | + | 26627737 | HCT116 | viability after 15 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.48670581523141515 | [171] | [177,98,142] | 4 | hSpCas9 | negative selection | 2136110 | 12145675 | 12145698 | 3 | - | 26627737 | HCT116 | viability after 15 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.6143196612669872 | [134] | [91,74,184] | 5 | hSpCas9 | negative selection | 2136111 | 12151242 | 12151265 | 3 | - | 26627737 | HCT116 | viability after 15 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 0.4486564910570481 | [62] | [30,73,40] | 4 | hSpCas9 | negative selection | 2136112 | 12161564 | 12161587 | 3 | - | 26627737 | HCT116 | viability after 15 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.14143710889703542 | [477] | [297,241,366] | 1 | hSpCas9 | negative selection | 2136125 | 12162116 | 12162139 | 3 | - | 26627737 | HCT116 | viability after 15 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.1499953775265639 | [625] | [441,448,311] | 1 | hSpCas9 | negative selection | 2136126 | 12141967 | 12141990 | 3 | + | 26627737 | HCT116 | viability after 18 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.01630739719488361 | [171] | [83,60,109] | 0 | hSpCas9 | negative selection | 2218425 | 12145675 | 12145698 | 3 | - | 26627737 | HCT116 | viability after 18 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | -0.4756857461273134 | [134] | [33,41,65] | -4 | hSpCas9 | negative selection | 2218426 | 12151242 | 12151265 | 3 | - | 26627737 | HCT116 | viability after 18 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | -0.31629348447864647 | [62] | [9,7,57] | -3 | hSpCas9 | negative selection | 2218427 | 12161564 | 12161587 | 3 | - | 26627737 | HCT116 | viability after 18 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.5165532269734463 | [477] | [346,158,504] | 4 | hSpCas9 | negative selection | 2218440 | 12162116 | 12162139 | 3 | - | 26627737 | HCT116 | viability after 18 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.32348578024355845 | [625] | [481,208,459] | 3 | hSpCas9 | negative selection | 2218441 | 12072018 | 12072041 | 3 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TACTGTTATGTGAGAACATTAGG | SYN2 | ENSG00000157152 | 2.314371024853204 | [564,203] | [798,7] | 7 | dCas9-VP64 | positive selection | 2384610 | 12069848 | 12069871 | 3 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CATGCCACTACACTCCATCCTGG | SYN2 | ENSG00000157152 | 1.9286097489754745 | [415,203] | [114,413] | 6 | dCas9-VP64 | positive selection | 2407206 | 12049972 | 12049995 | 3 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TCACTGCAACCTCCACCTCCAGG | SYN2 | ENSG00000157152 | 0.058421953785092295 | [801,622] | [115,212] | 0 | dCas9-VP64 | positive selection | 2420379 | 12159455 | 12159478 | 3 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GAACAGGACAGAGAAAGTTGGGG | SYN2 | ENSG00000157152 | 0.29297089795045034 | [65,35] | [9,16] | 1 | dCas9-VP64 | positive selection | 2432242 | 12159500 | 12159523 | 3 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GACATCTCTCCCCACCCCCCAGG | SYN2 | ENSG00000157152 | -0.19513168530423008 | [58,167] | [5,38] | -1 | dCas9-VP64 | positive selection | 2432243 | 12159482 | 12159505 | 3 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGTGTCTTGGCTCTGTTGCCTGG | SYN2 | ENSG00000157152 | 2.0312446287686847 | [13,143] | [7,141] | 7 | dCas9-VP64 | positive selection | 2432245 | 12053143 | 12053166 | 3 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGGCATGAGCCACCGTGCCTGG | SYN2 | ENSG00000157152 | -0.779191386983709 | [52,249] | [14,23] | -4 | dCas9-VP64 | positive selection | 2445738 | 12072018 | 12072041 | 3 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TACTGTTATGTGAGAACATTAGG | SYN2 | ENSG00000157152 | -0.6325467490050487 | [269,208] | [69,31] | -6 | dCas9-VP64 | positive selection | 2479865 | 12069848 | 12069871 | 3 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CATGCCACTACACTCCATCCTGG | SYN2 | ENSG00000157152 | -0.26102272442263375 | [369,548] | [99,147] | -2 | dCas9-VP64 | positive selection | 2502461 | 12049972 | 12049995 | 3 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TCACTGCAACCTCCACCTCCAGG | SYN2 | ENSG00000157152 | 0.1281772646791315 | [789,694] | [166,357] | 1 | dCas9-VP64 | positive selection | 2515634 | 12159455 | 12159478 | 3 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GAACAGGACAGAGAAAGTTGGGG | SYN2 | ENSG00000157152 | -1.0116596121616193 | [130,49] | [19,8] | -8 | dCas9-VP64 | positive selection | 2527497 | 12159500 | 12159523 | 3 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GACATCTCTCCCCACCCCCCAGG | SYN2 | ENSG00000157152 | -0.2161290117662163 | [104,71] | [38,10] | -2 | dCas9-VP64 | positive selection | 2527498 | 12159482 | 12159505 | 3 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGTGTCTTGGCTCTGTTGCCTGG | SYN2 | ENSG00000157152 | 0.9679009176862661 | [57,221] | [84,91] | 6 | dCas9-VP64 | positive selection | 2527500 | 12053143 | 12053166 | 3 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGGCATGAGCCACCGTGCCTGG | SYN2 | ENSG00000157152 | 0.389783500937638 | [291,598] | [109,262] | 3 | dCas9-VP64 | positive selection | 2540993 | 12141973 | 12141996 | 3 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.1025081023937311 | [284,284] | [1,1] | 0 | hSpCas9 | positive selection | 3395836 | 12168366 | 12168389 | 3 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.038157690983673484 | [148,148] | [0,0] | 0 | hSpCas9 | positive selection | 3395837 | 12140678 | 12140701 | 3 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.4244361972810935 | [113,113] | [0,0] | 2 | hSpCas9 | positive selection | 3395838 | 12140678 | 12140701 | 3 | + | 26780180 | A375 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.560719803658993 | [] | [] | 1 | hSpCas9 | negative selection | 4001249 | 12141973 | 12141996 | 3 | - | 26780180 | A375 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.460751799804069 | [] | [] | 1 | hSpCas9 | negative selection | 4001250 | 12141967 | 12141990 | 3 | + | 26780180 | A375 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.990691732032678 | [] | [] | 4 | hSpCas9 | negative selection | 4001251 | 12168366 | 12168389 | 3 | + | 26780180 | A375 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.929520304052853 | [] | [] | 4 | hSpCas9 | negative selection | 4001252 | 12140678 | 12140701 | 3 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 1.59166454596762 | [] | [] | 8 | hSpCas9 | negative selection | 4109215 | 12141973 | 12141996 | 3 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 1.46447105819705 | [] | [] | 7 | hSpCas9 | negative selection | 4109216 | 12141967 | 12141990 | 3 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.0742302561749451 | [] | [] | 0 | hSpCas9 | negative selection | 4109217 | 12168366 | 12168389 | 3 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.831722927494683 | [] | [] | 3 | hSpCas9 | negative selection | 4109218 | 12141967 | 12141990 | 3 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.17143597045195103 | [1] | [1,0] | -3 | hSpCas9 | positive selection | 4301582 | 12141973 | 12141996 | 3 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.5138779594435258 | [3] | [3,3] | 9 | hSpCas9 | positive selection | 4365835 | 12168366 | 12168389 | 3 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.019876440303807058 | [2] | [2,1] | 0 | hSpCas9 | positive selection | 4365836 | 12140678 | 12140701 | 3 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.06492207312428008 | [2] | [3,0] | 1 | hSpCas9 | positive selection | 4365837 | 12004402 | 12004425 | 3 | + | 27661255 | K562 | viability | GTCTGCGGGGTCTGGTGCCGGGG | SYN2 | ENSG00000157152 | 0.0049906099831000805 | [460,309] | [301,318] | 0 | dCas9-KRAB | negative selection | 5515447 | 12004391 | 12004414 | 3 | - | 27661255 | K562 | viability | GACCCCGCAGACAGCAGCGGCGG | SYN2 | ENSG00000157152 | 0.1546117325458508 | [931,1022] | [952,794] | 5 | dCas9-KRAB | negative selection | 5515448 | 12141967 | 12141990 | 3 | + | 27260156 | BXPC3 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.42553144329552284 | [193] | [201,337,317,228] | 8 | hSpCas9 | negative selection | 5574042 | 12141973 | 12141996 | 3 | - | 27260156 | BXPC3 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.3624991641714012 | [486] | [608,669,581,769] | 7 | hSpCas9 | negative selection | 5638295 | 12168366 | 12168389 | 3 | + | 27260156 | BXPC3 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.15828519008075215 | [338] | [268,307,258,453] | -4 | hSpCas9 | negative selection | 5638296 | 12140678 | 12140701 | 3 | + | 27260156 | BXPC3 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.07146209115707758 | [279] | [252,266,316,412] | 1 | hSpCas9 | negative selection | 5638297 | 12141967 | 12141990 | 3 | + | 27260156 | A673 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.3125818315454323 | [193] | [294,234,283,347] | 7 | hSpCas9 | negative selection | 5695293 | 12141973 | 12141996 | 3 | - | 27260156 | A673 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.20944846012192503 | [486] | [733,648,749,570] | 5 | hSpCas9 | negative selection | 5759546 | 12168366 | 12168389 | 3 | + | 27260156 | A673 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.16543148077809572 | [338] | [526,492,446,359] | 4 | hSpCas9 | negative selection | 5759547 | 12140678 | 12140701 | 3 | + | 27260156 | A673 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.07737127341988581 | [279] | [358,323,274,320] | -2 | hSpCas9 | negative selection | 5759548 | 12141967 | 12141990 | 3 | + | 27260156 | A375 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.21834955183179772 | [193] | [261,179,217,368] | 3 | hSpCas9 | negative selection | 5816544 | 12141973 | 12141996 | 3 | - | 27260156 | A375 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.523134958283782 | [486] | [666,989,875,762] | 7 | hSpCas9 | negative selection | 5880797 | 12168366 | 12168389 | 3 | + | 27260156 | A375 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.005924922455099013 | [338] | [352,559,378,315] | 0 | hSpCas9 | negative selection | 5880798 | 12140678 | 12140701 | 3 | + | 27260156 | A375 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.08569091137615759 | [279] | [230,607,362,233] | 1 | hSpCas9 | negative selection | 5880799 | 12141967 | 12141990 | 3 | + | 27260156 | COLO741 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.26182171661705134 | [193] | [344,309,243] | 5 | hSpCas9 | negative selection | 5937795 | 12141973 | 12141996 | 3 | - | 27260156 | COLO741 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.19808535150873585 | [486] | [684,731,719] | 4 | hSpCas9 | negative selection | 6002048 | 12168366 | 12168389 | 3 | + | 27260156 | COLO741 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.014129381864713075 | [338] | [424,410,447] | 0 | hSpCas9 | negative selection | 6002049 | 12140678 | 12140701 | 3 | + | 27260156 | COLO741 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.27060536651378275 | [279] | [386,428,470] | 5 | hSpCas9 | negative selection | 6002050 | 12141967 | 12141990 | 3 | + | 27260156 | CAL120 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.013970576826751735 | [193] | [135,392,186] | 0 | hSpCas9 | negative selection | 6059046 | 12141973 | 12141996 | 3 | - | 27260156 | CAL120 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.3566246449625539 | [486] | [1039,814,516] | 5 | hSpCas9 | negative selection | 6123299 | 12168366 | 12168389 | 3 | + | 27260156 | CAL120 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.3988497011222609 | [338] | [291,369,293] | -5 | hSpCas9 | negative selection | 6123300 | 12140678 | 12140701 | 3 | + | 27260156 | CAL120 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.25136649403000044 | [279] | [345,300,239] | -4 | hSpCas9 | negative selection | 6123301 | 12141967 | 12141990 | 3 | + | 27260156 | CADOES1 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.0159219113713589 | [193] | [174,201,154,181] | 0 | hSpCas9 | negative selection | 6180297 | 12141973 | 12141996 | 3 | - | 27260156 | CADOES1 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.45460503152003856 | [486] | [619,675,539,647] | 7 | hSpCas9 | negative selection | 6244550 | 12168366 | 12168389 | 3 | + | 27260156 | CADOES1 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.16827048612993784 | [338] | [328,385,253,451] | 3 | hSpCas9 | negative selection | 6244551 | 12140678 | 12140701 | 3 | + | 27260156 | CADOES1 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.4527612981822164 | [279] | [362,392,306,362] | 7 | hSpCas9 | negative selection | 6244552 | 12141967 | 12141990 | 3 | + | 27260156 | EWS502 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.33888496949581537 | [193] | [121,214,236,499] | 6 | hSpCas9 | negative selection | 6301548 | 12141973 | 12141996 | 3 | - | 27260156 | EWS502 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.15761730779270966 | [486] | [449,630,661,569] | 2 | hSpCas9 | negative selection | 6365801 | 12168366 | 12168389 | 3 | + | 27260156 | EWS502 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.14733715036430967 | [338] | [450,453,350,317] | 2 | hSpCas9 | negative selection | 6365802 | 12140678 | 12140701 | 3 | + | 27260156 | EWS502 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.14014903289189273 | [279] | [165,255,534,377] | 2 | hSpCas9 | negative selection | 6365803 | 12141967 | 12141990 | 3 | + | 27260156 | EW8 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.4472082980203961 | [193] | [195,199,199,260] | 7 | hSpCas9 | negative selection | 6422799 | 12141973 | 12141996 | 3 | - | 27260156 | EW8 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.6477085171768737 | [486] | [831,531,533,610] | 9 | hSpCas9 | negative selection | 6487052 | 12168366 | 12168389 | 3 | + | 27260156 | EW8 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.2925553463047047 | [338] | [379,295,357,311] | 5 | hSpCas9 | negative selection | 6487053 | 12140678 | 12140701 | 3 | + | 27260156 | EW8 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.28197832178635435 | [279] | [350,221,286,248] | 5 | hSpCas9 | negative selection | 6487054 | 12141967 | 12141990 | 3 | + | 27260156 | CORL105 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.3156538272772146 | [193] | [256,217,347,317] | 6 | hSpCas9 | negative selection | 6544050 | 12141973 | 12141996 | 3 | - | 27260156 | CORL105 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.39820527349102597 | [486] | [782,693,849,695] | 7 | hSpCas9 | negative selection | 6608303 | 12168366 | 12168389 | 3 | + | 27260156 | CORL105 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.09661927354338906 | [338] | [343,513,425,205] | -2 | hSpCas9 | negative selection | 6608304 | 12140678 | 12140701 | 3 | + | 27260156 | CORL105 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.15615042687141878 | [279] | [247,334,286,302] | -3 | hSpCas9 | negative selection | 6608305 | 12141967 | 12141990 | 3 | + | 27260156 | HS294T | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.3425303232279615 | [193] | [61,57,57,57] | -5 | hSpCas9 | negative selection | 6665301 | 12141973 | 12141996 | 3 | - | 27260156 | HS294T | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.6358201187867363 | [486] | [300,333,194,345] | 8 | hSpCas9 | negative selection | 6729554 | 12168366 | 12168389 | 3 | + | 27260156 | HS294T | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.19042201770402012 | [338] | [111,96,100,156] | -3 | hSpCas9 | negative selection | 6729555 | 12140678 | 12140701 | 3 | + | 27260156 | HS294T | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.29621076757698594 | [279] | [89,92,85,81] | -4 | hSpCas9 | negative selection | 6729556 | 12141967 | 12141990 | 3 | + | 27260156 | HCC44 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.6210527976696717 | [193] | [245,224,442,454] | 8 | hSpCas9 | negative selection | 6786552 | 12141973 | 12141996 | 3 | - | 27260156 | HCC44 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.21886872597170115 | [486] | [644,524,807,626] | 3 | hSpCas9 | negative selection | 6850805 | 12168366 | 12168389 | 3 | + | 27260156 | HCC44 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.4076299337962477 | [338] | [434,443,361,757] | 6 | hSpCas9 | negative selection | 6850806 | 12140678 | 12140701 | 3 | + | 27260156 | HCC44 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.15248432377819154 | [279] | [271,303,310,251] | -2 | hSpCas9 | negative selection | 6850807 | 12141967 | 12141990 | 3 | + | 27260156 | G402 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.8270630541558035 | [193] | [658,349,265,432] | 8 | hSpCas9 | negative selection | 6907803 | 12141973 | 12141996 | 3 | - | 27260156 | G402 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.4645878301920526 | [486] | [889,715,602,1059] | 6 | hSpCas9 | negative selection | 6972056 | 12168366 | 12168389 | 3 | + | 27260156 | G402 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.18994714492811887 | [338] | [432,574,342,531] | 2 | hSpCas9 | negative selection | 6972057 | 12140678 | 12140701 | 3 | + | 27260156 | G402 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.09104917751824004 | [279] | [531,324,355,267] | 1 | hSpCas9 | negative selection | 6972058 | 12141967 | 12141990 | 3 | + | 27260156 | L33 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.10285243817082113 | [193] | [166,89,137,227] | 2 | hSpCas9 | negative selection | 7029054 | 12141973 | 12141996 | 3 | - | 27260156 | L33 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.12289866419159827 | [486] | [488,217,302,617] | 2 | hSpCas9 | negative selection | 7093307 | 12168366 | 12168389 | 3 | + | 27260156 | L33 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.06579789782751161 | [338] | [350,90,268,417] | 1 | hSpCas9 | negative selection | 7093308 | 12140678 | 12140701 | 3 | + | 27260156 | L33 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.3196768591995335 | [279] | [179,99,145,241] | -6 | hSpCas9 | negative selection | 7093309 | 12141967 | 12141990 | 3 | + | 27260156 | K562 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.3992856676653538 | [193] | [154,209,90,77] | -5 | hSpCas9 | negative selection | 7150305 | 12141973 | 12141996 | 3 | - | 27260156 | K562 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.31341052484332627 | [486] | [738,287,685,446] | 4 | hSpCas9 | negative selection | 7214558 | 12168366 | 12168389 | 3 | + | 27260156 | K562 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.6187884007685245 | [338] | [89,143,148,367] | -6 | hSpCas9 | negative selection | 7214559 | 12140678 | 12140701 | 3 | + | 27260156 | K562 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.20388863376089217 | [279] | [185,343,374,238] | 2 | hSpCas9 | negative selection | 7214560 | 12141967 | 12141990 | 3 | + | 27260156 | HT29 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.403090825767927 | [193] | [297,389,315,253] | 7 | hSpCas9 | negative selection | 7271556 | 12141973 | 12141996 | 3 | - | 27260156 | HT29 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.4785751752936009 | [486] | [848,898,901,670] | 8 | hSpCas9 | negative selection | 7335809 | 12168366 | 12168389 | 3 | + | 27260156 | HT29 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.10522986493550363 | [338] | [439,516,465,362] | 2 | hSpCas9 | negative selection | 7335810 | 12140678 | 12140701 | 3 | + | 27260156 | HT29 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.1178311657374097 | [279] | [324,298,349,281] | -2 | hSpCas9 | negative selection | 7335811 | 12141967 | 12141990 | 3 | + | 27260156 | MHHES1 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.3410438821924652 | [193] | [354,347,139,273] | 6 | hSpCas9 | negative selection | 7392807 | 12141973 | 12141996 | 3 | - | 27260156 | MHHES1 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.3213513111738584 | [486] | [556,838,622,701] | 6 | hSpCas9 | negative selection | 7457060 | 12168366 | 12168389 | 3 | + | 27260156 | MHHES1 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.362560208928148 | [338] | [648,231,550,508] | 6 | hSpCas9 | negative selection | 7457061 | 12140678 | 12140701 | 3 | + | 27260156 | MHHES1 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.4021349121949373 | [279] | [565,290,457,360] | 7 | hSpCas9 | negative selection | 7457062 | 12141967 | 12141990 | 3 | + | 27260156 | MEWO | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.15560392702560866 | [193] | [194,162,136] | -3 | hSpCas9 | negative selection | 7514058 | 12141973 | 12141996 | 3 | - | 27260156 | MEWO | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.12224590908951301 | [486] | [528,500,463] | 2 | hSpCas9 | negative selection | 7578311 | 12168366 | 12168389 | 3 | + | 27260156 | MEWO | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.40182452673624813 | [338] | [371,388,486] | 8 | hSpCas9 | negative selection | 7578312 | 12140678 | 12140701 | 3 | + | 27260156 | MEWO | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.16457309476584836 | [279] | [155,241,287] | -4 | hSpCas9 | negative selection | 7578313 | 12141967 | 12141990 | 3 | + | 27260156 | LNCAPCLONEFGC | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.22656231113048864 | [193] | [133,188,226,277] | 3 | hSpCas9 | negative selection | 7635309 | 12141973 | 12141996 | 3 | - | 27260156 | LNCAPCLONEFGC | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.4795218580826243 | [486] | [490,495,963,570] | 7 | hSpCas9 | negative selection | 7699562 | 12168366 | 12168389 | 3 | + | 27260156 | LNCAPCLONEFGC | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.19430981986978524 | [338] | [274,295,530,334] | 3 | hSpCas9 | negative selection | 7699563 | 12140678 | 12140701 | 3 | + | 27260156 | LNCAPCLONEFGC | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.15362829921624255 | [279] | [348,265,287,225] | 2 | hSpCas9 | negative selection | 7699564 | 12141967 | 12141990 | 3 | + | 27260156 | PANC0327 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.025008523845795105 | [193] | [374,117,98,132] | 0 | hSpCas9 | negative selection | 7756560 | 12141973 | 12141996 | 3 | - | 27260156 | PANC0327 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.3741885334311144 | [486] | [499,392,492,872] | 5 | hSpCas9 | negative selection | 7820813 | 12168366 | 12168389 | 3 | + | 27260156 | PANC0327 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.07984270351681655 | [338] | [508,260,204,185] | -1 | hSpCas9 | negative selection | 7820814 | 12140678 | 12140701 | 3 | + | 27260156 | PANC0327 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.019954707944587313 | [279] | [403,306,170,131] | 0 | hSpCas9 | negative selection | 7820815 | 12141967 | 12141990 | 3 | + | 27260156 | NCIH2009 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.41361366395373134 | [193] | [297,473,295] | 6 | hSpCas9 | negative selection | 7877811 | 12141973 | 12141996 | 3 | - | 27260156 | NCIH2009 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.4327917080952284 | [486] | [1168,715,921] | 6 | hSpCas9 | negative selection | 7942064 | 12168366 | 12168389 | 3 | + | 27260156 | NCIH2009 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.1330286706645109 | [338] | [668,455,462] | 1 | hSpCas9 | negative selection | 7942065 | 12140678 | 12140701 | 3 | + | 27260156 | NCIH2009 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.3637790211158606 | [279] | [310,298,302] | -5 | hSpCas9 | negative selection | 7942066 | 12141967 | 12141990 | 3 | + | 27260156 | NCIH1373 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.04664982902403536 | [193] | [202,321,96,69] | 0 | hSpCas9 | negative selection | 7999062 | 12141973 | 12141996 | 3 | - | 27260156 | NCIH1373 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.7487736702546587 | [486] | [1011,1217,762,167] | 7 | hSpCas9 | negative selection | 8063315 | 12168366 | 12168389 | 3 | + | 27260156 | NCIH1373 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.13724322594132554 | [338] | [667,362,421,65] | 1 | hSpCas9 | negative selection | 8063316 | 12140678 | 12140701 | 3 | + | 27260156 | NCIH1373 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.12073475386509513 | [279] | [397,614,105,57] | 1 | hSpCas9 | negative selection | 8063317 | 12141967 | 12141990 | 3 | + | 27260156 | PATU8902 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.47429674759479334 | [193] | [300,376,365,468] | 5 | hSpCas9 | negative selection | 8120313 | 12141973 | 12141996 | 3 | - | 27260156 | PATU8902 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.696207756821697 | [486] | [1266,1090,1029,1002] | 7 | hSpCas9 | negative selection | 8184566 | 12168366 | 12168389 | 3 | + | 27260156 | PATU8902 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.8316391837456549 | [338] | [426,2091,445,454] | 8 | hSpCas9 | negative selection | 8184567 | 12140678 | 12140701 | 3 | + | 27260156 | PATU8902 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.16801450022002595 | [279] | [103,633,427,182] | -2 | hSpCas9 | negative selection | 8184568 | 12141967 | 12141990 | 3 | + | 27260156 | PANC1 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.6344658929883291 | [193] | [281,257,194,288] | 8 | hSpCas9 | negative selection | 8241564 | 12141973 | 12141996 | 3 | - | 27260156 | PANC1 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.32559911668163377 | [486] | [454,690,504,479] | 5 | hSpCas9 | negative selection | 8305817 | 12168366 | 12168389 | 3 | + | 27260156 | PANC1 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.1828253493451375 | [338] | [232,257,296,237] | -3 | hSpCas9 | negative selection | 8305818 | 12140678 | 12140701 | 3 | + | 27260156 | PANC1 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.28943399067548364 | [279] | [205,487,329,203] | 4 | hSpCas9 | negative selection | 8305819 | 12141967 | 12141990 | 3 | + | 27260156 | PANC0813 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.4581615674219338 | [193] | [380,312,272,291] | 7 | hSpCas9 | negative selection | 8362815 | 12141973 | 12141996 | 3 | - | 27260156 | PANC0813 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.10441574055093049 | [486] | [611,542,670,631] | 1 | hSpCas9 | negative selection | 8427068 | 12168366 | 12168389 | 3 | + | 27260156 | PANC0813 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.3258911297738668 | [338] | [668,427,654,272] | 5 | hSpCas9 | negative selection | 8427069 | 12140678 | 12140701 | 3 | + | 27260156 | PANC0813 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.27024635786009055 | [279] | [407,186,272,236] | -4 | hSpCas9 | negative selection | 8427070 | 12141967 | 12141990 | 3 | + | 27260156 | RDES | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.4584600257367345 | [193] | [267,327,239,397] | 7 | hSpCas9 | negative selection | 8484066 | 12141973 | 12141996 | 3 | - | 27260156 | RDES | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.5260931752079255 | [486] | [697,599,868,1129] | 8 | hSpCas9 | negative selection | 8548319 | 12168366 | 12168389 | 3 | + | 27260156 | RDES | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.036030457823064466 | [338] | [367,382,343,419] | 0 | hSpCas9 | negative selection | 8548320 | 12140678 | 12140701 | 3 | + | 27260156 | RDES | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.11112230983767246 | [279] | [224,334,431,433] | 1 | hSpCas9 | negative selection | 8548321 | 12141967 | 12141990 | 3 | + | 27260156 | PC3 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.5247476137739169 | [193] | [217,296,385,243] | 9 | hSpCas9 | negative selection | 8605317 | 12141973 | 12141996 | 3 | - | 27260156 | PC3 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.16018720859953384 | [486] | [292,434,1057,659] | 3 | hSpCas9 | negative selection | 8669570 | 12168366 | 12168389 | 3 | + | 27260156 | PC3 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.034177396238978974 | [338] | [253,287,494,344] | 0 | hSpCas9 | negative selection | 8669571 | 12140678 | 12140701 | 3 | + | 27260156 | PC3 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.20455220083391723 | [279] | [170,210,881,285] | 4 | hSpCas9 | negative selection | 8669572 | 12141967 | 12141990 | 3 | + | 27260156 | PATU8988T | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.44770417705189325 | [193] | [126,212,472,197] | 7 | hSpCas9 | negative selection | 8726568 | 12141973 | 12141996 | 3 | - | 27260156 | PATU8988T | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.6734263869050009 | [486] | [1129,667,453,745] | 9 | hSpCas9 | negative selection | 8790821 | 12168366 | 12168389 | 3 | + | 27260156 | PATU8988T | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.24686371894986905 | [338] | [293,498,384,386] | 4 | hSpCas9 | negative selection | 8790822 | 12140678 | 12140701 | 3 | + | 27260156 | PATU8988T | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.31001032725546973 | [279] | [440,304,344,239] | 5 | hSpCas9 | negative selection | 8790823 | 12141967 | 12141990 | 3 | + | 27260156 | T47D | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.11093869366672382 | [193] | [277,231,217,249] | 2 | hSpCas9 | negative selection | 8847819 | 12141973 | 12141996 | 3 | - | 27260156 | T47D | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.41221162629917407 | [486] | [820,673,769,761] | 8 | hSpCas9 | negative selection | 8912072 | 12168366 | 12168389 | 3 | + | 27260156 | T47D | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.16534469566996596 | [338] | [489,382,430,473] | 3 | hSpCas9 | negative selection | 8912073 | 12140678 | 12140701 | 3 | + | 27260156 | T47D | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.1274405385899695 | [279] | [272,425,375,342] | 2 | hSpCas9 | negative selection | 8912074 | 12141967 | 12141990 | 3 | + | 27260156 | SU8686 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.17339247693815008 | [193] | [223,233,137,273] | 3 | hSpCas9 | negative selection | 8969070 | 12141973 | 12141996 | 3 | - | 27260156 | SU8686 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.3022272973182377 | [486] | [633,578,563,596] | 5 | hSpCas9 | negative selection | 9033323 | 12168366 | 12168389 | 3 | + | 27260156 | SU8686 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.1967971991439736 | [338] | [409,321,380,438] | 3 | hSpCas9 | negative selection | 9033324 | 12140678 | 12140701 | 3 | + | 27260156 | SU8686 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.11937137507205187 | [279] | [253,252,182,342] | -2 | hSpCas9 | negative selection | 9033325 | 12141967 | 12141990 | 3 | + | 27260156 | SKES1 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.381642942364688 | [193] | [210,415,242,160] | 7 | hSpCas9 | negative selection | 9090321 | 12141973 | 12141996 | 3 | - | 27260156 | SKES1 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.3744479103047241 | [486] | [719,491,657,636] | 7 | hSpCas9 | negative selection | 9154574 | 12168366 | 12168389 | 3 | + | 27260156 | SKES1 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.08230169565719503 | [338] | [270,376,331,296] | -2 | hSpCas9 | negative selection | 9154575 | 12140678 | 12140701 | 3 | + | 27260156 | SKES1 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.19412322977533936 | [279] | [336,446,312,208] | 4 | hSpCas9 | negative selection | 9154576 | 12141967 | 12141990 | 3 | + | 27260156 | TOV112D | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.6189719326586399 | [193] | [329,435,141,320] | 9 | hSpCas9 | negative selection | 9211572 | 12141973 | 12141996 | 3 | - | 27260156 | TOV112D | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.23714101567501722 | [486] | [775,681,456,430] | 4 | hSpCas9 | negative selection | 9275825 | 12168366 | 12168389 | 3 | + | 27260156 | TOV112D | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.004711977418541069 | [338] | [325,562,203,314] | 0 | hSpCas9 | negative selection | 9275826 | 12140678 | 12140701 | 3 | + | 27260156 | TOV112D | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.36130637807437693 | [279] | [219,705,239,347] | 6 | hSpCas9 | negative selection | 9275827 | 12141967 | 12141990 | 3 | + | 27260156 | TC71 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.19939492123576263 | [193] | [284,272,225,165] | 5 | hSpCas9 | negative selection | 9332823 | 12141973 | 12141996 | 3 | - | 27260156 | TC71 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.2150384164945096 | [486] | [563,570,533,767] | 5 | hSpCas9 | negative selection | 9397076 | 12168366 | 12168389 | 3 | + | 27260156 | TC71 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | 0.035890537734266814 | [338] | [472,323,345,343] | 0 | hSpCas9 | negative selection | 9397077 | 12140678 | 12140701 | 3 | + | 27260156 | TC71 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | 0.24392199578729423 | [279] | [346,297,287,499] | 6 | hSpCas9 | negative selection | 9397078 | 12141967 | 12141990 | 3 | + | 27260156 | TC32 | viability | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.17699206955765745 | [193] | [164,111,275,319] | 3 | hSpCas9 | negative selection | 9454074 | 12141973 | 12141996 | 3 | - | 27260156 | TC32 | viability | GGACAACCTTTGTGCCATTCCGG | SYN2 | ENSG00000157152 | 0.46768869518800954 | [486] | [594,552,837,572] | 7 | hSpCas9 | negative selection | 9518327 | 12168366 | 12168389 | 3 | + | 27260156 | TC32 | viability | TCACCTCCAGGTACAAACTGTGG | SYN2 | ENSG00000157152 | -0.00384197916007345 | [338] | [176,329,359,409] | 0 | hSpCas9 | negative selection | 9518328 | 12140678 | 12140701 | 3 | + | 27260156 | TC32 | viability | CCTTGGAGATTATGATATCAAGG | SYN2 | ENSG00000157152 | -0.13414158676721877 | [279] | [280,165,308,221] | -2 | hSpCas9 | negative selection | 9518329 | 12141967 | 12141990 | 3 | + | 27869803 | HPAFII | viability after 27 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.5884346926279612 | [168] | [75,44,NaN] | -4 | hSpCas9 | negative selection | 9582141 | 12145675 | 12145698 | 3 | - | 27869803 | HPAFII | viability after 27 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.7208142681886549 | [127] | [225,14,NaN] | 6 | hSpCas9 | negative selection | 9582142 | 12151242 | 12151265 | 3 | - | 27869803 | HPAFII | viability after 27 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | -0.9194079271183306 | [103] | [41,17,NaN] | -6 | hSpCas9 | negative selection | 9582143 | 12161564 | 12161587 | 3 | - | 27869803 | HPAFII | viability after 27 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 1.2642366466065105 | [302] | [584,213,NaN] | 9 | hSpCas9 | negative selection | 9582156 | 12162116 | 12162139 | 3 | - | 27869803 | HPAFII | viability after 27 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.37269167649050194 | [450] | [318,296,NaN] | 3 | hSpCas9 | negative selection | 9582157 | 12141967 | 12141990 | 3 | + | 27869803 | HPAFII | viability after 15 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.11604609201395727 | [168] | [120,243,NaN] | 1 | hSpCas9 | negative selection | 9664590 | 12145675 | 12145698 | 3 | - | 27869803 | HPAFII | viability after 15 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.4550547993814956 | [127] | [322,104,NaN] | 5 | hSpCas9 | negative selection | 9664591 | 12151242 | 12151265 | 3 | - | 27869803 | HPAFII | viability after 15 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | -0.45090865570771843 | [103] | [119,57,NaN] | -5 | hSpCas9 | negative selection | 9664592 | 12161564 | 12161587 | 3 | - | 27869803 | HPAFII | viability after 15 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.884289195922702 | [302] | [1020,339,NaN] | 8 | hSpCas9 | negative selection | 9664605 | 12162116 | 12162139 | 3 | - | 27869803 | HPAFII | viability after 15 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.759013244434098 | [450] | [950,738,NaN] | 8 | hSpCas9 | negative selection | 9664606 | 12141967 | 12141990 | 3 | + | 27869803 | ASPC1 | viability after 36 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.2229053720789499 | [340] | [75,310,44] | 2 | hSpCas9 | negative selection | 9747039 | 12145675 | 12145698 | 3 | - | 27869803 | ASPC1 | viability after 36 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | -0.7415643722927859 | [326] | [64,57,77] | -6 | hSpCas9 | negative selection | 9747040 | 12151242 | 12151265 | 3 | - | 27869803 | ASPC1 | viability after 36 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | -0.21142198823065872 | [248] | [43,117,61] | -2 | hSpCas9 | negative selection | 9747041 | 12161564 | 12161587 | 3 | - | 27869803 | ASPC1 | viability after 36 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.3041949934828051 | [1110] | [434,597,409] | 3 | hSpCas9 | negative selection | 9747054 | 12162116 | 12162139 | 3 | - | 27869803 | ASPC1 | viability after 36 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 1.8842410099483615 | [1122] | [506,764,2632] | 9 | hSpCas9 | negative selection | 9747055 | 12141967 | 12141990 | 3 | + | 27869803 | PATU8988S | viability after 35 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 1.0831970829548216 | [347] | [276,316,NaN] | 9 | hSpCas9 | negative selection | 9829488 | 12145675 | 12145698 | 3 | - | 27869803 | PATU8988S | viability after 35 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | -0.2110829492036127 | [305] | [91,120,NaN] | -2 | hSpCas9 | negative selection | 9829489 | 12151242 | 12151265 | 3 | - | 27869803 | PATU8988S | viability after 35 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 0.6849821854307033 | [179] | [137,94,NaN] | 7 | hSpCas9 | negative selection | 9829490 | 12161564 | 12161587 | 3 | - | 27869803 | PATU8988S | viability after 35 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.19796452087611904 | [685] | [282,350,NaN] | 2 | hSpCas9 | negative selection | 9829503 | 12162116 | 12162139 | 3 | - | 27869803 | PATU8988S | viability after 35 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.31203155991663845 | [878] | [437,440,NaN] | 3 | hSpCas9 | negative selection | 9829504 | 12141967 | 12141990 | 3 | + | 27869803 | PATU8988S | viability after 31 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 1.0970164643003077 | [347] | [247,358,NaN] | 9 | hSpCas9 | negative selection | 9911937 | 12145675 | 12145698 | 3 | - | 27869803 | PATU8988S | viability after 31 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.4076969954690162 | [305] | [72,274,NaN] | 5 | hSpCas9 | negative selection | 9911938 | 12151242 | 12151265 | 3 | - | 27869803 | PATU8988S | viability after 31 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | 0.6537794306822629 | [179] | [115,108,NaN] | 7 | hSpCas9 | negative selection | 9911939 | 12161564 | 12161587 | 3 | - | 27869803 | PATU8988S | viability after 31 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 0.2511422755601792 | [685] | [281,380,NaN] | 3 | hSpCas9 | negative selection | 9911952 | 12162116 | 12162139 | 3 | - | 27869803 | PATU8988S | viability after 31 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.4482783566156746 | [878] | [380,601,NaN] | 5 | hSpCas9 | negative selection | 9911953 | 12141967 | 12141990 | 3 | + | 27869803 | HPAFII | viability after 35 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | 0.21223515645590174 | [168] | [92,105,NaN] | 1 | hSpCas9 | negative selection | 9994386 | 12145675 | 12145698 | 3 | - | 27869803 | HPAFII | viability after 35 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.8383479841405809 | [127] | [192,28,NaN] | 5 | hSpCas9 | negative selection | 9994387 | 12151242 | 12151265 | 3 | - | 27869803 | HPAFII | viability after 35 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | -0.08445134444223679 | [103] | [67,28,NaN] | 0 | hSpCas9 | negative selection | 9994388 | 12161564 | 12161587 | 3 | - | 27869803 | HPAFII | viability after 35 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 1.836863404068712 | [302] | [721,351,NaN] | 9 | hSpCas9 | negative selection | 9994401 | 12162116 | 12162139 | 3 | - | 27869803 | HPAFII | viability after 35 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.5430955710209526 | [450] | [279,391,NaN] | 3 | hSpCas9 | negative selection | 9994402 | 12141967 | 12141990 | 3 | + | 27869803 | HPAFII | viability after 31 days | GGTTCTCCGGAATGGCACAAAGG | SYN2 | ENSG00000157152 | -0.4681228516171033 | [168] | [69,66,NaN] | -3 | hSpCas9 | negative selection | 10076835 | 12145675 | 12145698 | 3 | - | 27869803 | HPAFII | viability after 31 days | GAAGTCTGGCCGGAAGGACCTGG | SYN2 | ENSG00000157152 | 0.3202923925845883 | [127] | [160,11,NaN] | 2 | hSpCas9 | negative selection | 10076836 | 12151242 | 12151265 | 3 | - | 27869803 | HPAFII | viability after 31 days | TCTTATAGATAGCGACCAGCTGG | SYN2 | ENSG00000157152 | -0.5819305536643831 | [103] | [49,26,NaN] | -4 | hSpCas9 | negative selection | 10076837 | 12161564 | 12161587 | 3 | - | 27869803 | HPAFII | viability after 31 days | TGGCCAATCTTCACCACCACAGG | SYN2 | ENSG00000157152 | 1.4186057530166596 | [302] | [623,269,NaN] | 9 | hSpCas9 | negative selection | 10076850 | 12162116 | 12162139 | 3 | - | 27869803 | HPAFII | viability after 31 days | TGTTGCCAATCTTCTGGACCCGG | SYN2 | ENSG00000157152 | 0.20797560580535746 | [450] | [277,307,NaN] | 1 | hSpCas9 | negative selection | 10076851 | 12004613 | 12004636 | 3 | + | 28162770 | P31FUJ | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | 0.2637304128551663 | [683] | [964] | 3 | hSpCas9 | negative selection | 10246022 | 12161548 | 12161571 | 3 | + | 28162770 | P31FUJ | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | 0.3526415957410629 | [998] | [1498] | 4 | hSpCas9 | negative selection | 10246023 | 12151252 | 12151275 | 3 | + | 28162770 | P31FUJ | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | 0.08444940326351036 | [617] | [769] | 0 | hSpCas9 | negative selection | 10246024 | 12169780 | 12169803 | 3 | + | 28162770 | P31FUJ | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | 0.26628517233957893 | [945] | [1336] | 3 | hSpCas9 | negative selection | 10246025 | 12004877 | 12004900 | 3 | - | 28162770 | P31FUJ | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | 0.11176856709424854 | [1630] | [2070] | 1 | hSpCas9 | negative selection | 10246026 | 12141937 | 12141960 | 3 | + | 28162770 | P31FUJ | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | 0.6143889523062291 | [795] | [1431] | 7 | hSpCas9 | negative selection | 10246027 | 12145709 | 12145732 | 3 | + | 28162770 | P31FUJ | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | 0.5931236645481586 | [1653] | [2931] | 6 | hSpCas9 | negative selection | 10246028 | 12145745 | 12145768 | 3 | - | 28162770 | P31FUJ | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | 0.2941147671757969 | [802] | [1156] | 3 | hSpCas9 | negative selection | 10246029 | 12145778 | 12145801 | 3 | - | 28162770 | P31FUJ | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.3777520102095182 | [1489] | [2274] | 4 | hSpCas9 | negative selection | 10246030 | 12004613 | 12004636 | 3 | + | 28162770 | TF1 | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | NaN | [NaN] | [197] | 1 | hSpCas9 | negative selection | 10415388 | 12161548 | 12161571 | 3 | + | 28162770 | TF1 | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | NaN | [NaN] | [85] | 1 | hSpCas9 | negative selection | 10415389 | 12151252 | 12151275 | 3 | + | 28162770 | TF1 | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | NaN | [NaN] | [158] | 1 | hSpCas9 | negative selection | 10415390 | 12169780 | 12169803 | 3 | + | 28162770 | TF1 | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | NaN | [NaN] | [168] | 1 | hSpCas9 | negative selection | 10415391 | 12004877 | 12004900 | 3 | - | 28162770 | TF1 | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | NaN | [NaN] | [271] | 1 | hSpCas9 | negative selection | 10415392 | 12141937 | 12141960 | 3 | + | 28162770 | TF1 | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | NaN | [NaN] | [201] | 1 | hSpCas9 | negative selection | 10415393 | 12145709 | 12145732 | 3 | + | 28162770 | TF1 | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | NaN | [NaN] | [267] | 1 | hSpCas9 | negative selection | 10415394 | 12145745 | 12145768 | 3 | - | 28162770 | TF1 | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | NaN | [NaN] | [154] | 1 | hSpCas9 | negative selection | 10415395 | 12145778 | 12145801 | 3 | - | 28162770 | TF1 | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | NaN | [NaN] | [215] | 1 | hSpCas9 | negative selection | 10415396 | 12004613 | 12004636 | 3 | + | 28162770 | SKM1 | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | -0.689551401998356 | [51] | [56] | -5 | hSpCas9 | negative selection | 10584754 | 12161548 | 12161571 | 3 | + | 28162770 | SKM1 | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | 0.6864626652251071 | [70] | [201] | 6 | hSpCas9 | negative selection | 10584755 | 12151252 | 12151275 | 3 | + | 28162770 | SKM1 | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | 0.27753397552890885 | [41] | [89] | 2 | hSpCas9 | negative selection | 10584756 | 12169780 | 12169803 | 3 | + | 28162770 | SKM1 | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | 0.6161194143698795 | [61] | [167] | 6 | hSpCas9 | negative selection | 10584757 | 12004877 | 12004900 | 3 | - | 28162770 | SKM1 | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | 0.40039072331444236 | [86] | [202] | 4 | hSpCas9 | negative selection | 10584758 | 12141937 | 12141960 | 3 | + | 28162770 | SKM1 | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | 0.5190352198130613 | [59] | [151] | 5 | hSpCas9 | negative selection | 10584759 | 12145709 | 12145732 | 3 | + | 28162770 | SKM1 | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | 1.3225301459919094 | [120] | [534] | 9 | hSpCas9 | negative selection | 10584760 | 12145745 | 12145768 | 3 | - | 28162770 | SKM1 | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | 0.2654611432283339 | [47] | [101] | 2 | hSpCas9 | negative selection | 10584761 | 12145778 | 12145801 | 3 | - | 28162770 | SKM1 | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.6170044490831692 | [96] | [262] | 6 | hSpCas9 | negative selection | 10584762 | 12004613 | 12004636 | 3 | + | 28162770 | SKM1 | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | -0.689551401998356 | [51] | [56] | -5 | hSpCas9 | negative selection | 10754120 | 12161548 | 12161571 | 3 | + | 28162770 | SKM1 | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | 0.6864626652251071 | [70] | [201] | 6 | hSpCas9 | negative selection | 10754121 | 12151252 | 12151275 | 3 | + | 28162770 | SKM1 | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | 0.27753397552890885 | [41] | [89] | 2 | hSpCas9 | negative selection | 10754122 | 12169780 | 12169803 | 3 | + | 28162770 | SKM1 | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | 0.6161194143698795 | [61] | [167] | 6 | hSpCas9 | negative selection | 10754123 | 12004877 | 12004900 | 3 | - | 28162770 | SKM1 | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | 0.40039072331444236 | [86] | [202] | 4 | hSpCas9 | negative selection | 10754124 | 12141937 | 12141960 | 3 | + | 28162770 | SKM1 | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | 0.5190352198130613 | [59] | [151] | 5 | hSpCas9 | negative selection | 10754125 | 12145709 | 12145732 | 3 | + | 28162770 | SKM1 | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | 1.3225301459919094 | [120] | [534] | 9 | hSpCas9 | negative selection | 10754126 | 12145745 | 12145768 | 3 | - | 28162770 | SKM1 | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | 0.2654611432283339 | [47] | [101] | 2 | hSpCas9 | negative selection | 10754127 | 12145778 | 12145801 | 3 | - | 28162770 | SKM1 | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.6170044490831692 | [96] | [262] | 6 | hSpCas9 | negative selection | 10754128 | 12004613 | 12004636 | 3 | + | 28162770 | PL21 | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | 0.7880859736492978 | [160] | [120] | 6 | hSpCas9 | negative selection | 10923486 | 12161548 | 12161571 | 3 | + | 28162770 | PL21 | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | 0.42876398953728245 | [197] | [115] | 4 | hSpCas9 | negative selection | 10923487 | 12151252 | 12151275 | 3 | + | 28162770 | PL21 | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | 0.62714975543424 | [179] | [120] | 5 | hSpCas9 | negative selection | 10923488 | 12169780 | 12169803 | 3 | + | 28162770 | PL21 | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | -0.35928779412469836 | [223] | [75] | -3 | hSpCas9 | negative selection | 10923489 | 12004877 | 12004900 | 3 | - | 28162770 | PL21 | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | 0.8816100960638229 | [423] | [339] | 7 | hSpCas9 | negative selection | 10923490 | 12141937 | 12141960 | 3 | + | 28162770 | PL21 | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | 0.15782880963135584 | [172] | [83] | 1 | hSpCas9 | negative selection | 10923491 | 12145709 | 12145732 | 3 | + | 28162770 | PL21 | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | 1.2485442464523746 | [380] | [393] | 8 | hSpCas9 | negative selection | 10923492 | 12145745 | 12145768 | 3 | - | 28162770 | PL21 | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | -1.331874006282877 | [213] | [36] | -7 | hSpCas9 | negative selection | 10923493 | 12145778 | 12145801 | 3 | - | 28162770 | PL21 | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.1261390330455433 | [359] | [170] | 1 | hSpCas9 | negative selection | 10923494 | 12004613 | 12004636 | 3 | + | 28162770 | P31FUJ | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | 0.2637304128551663 | [683] | [964] | 3 | hSpCas9 | negative selection | 11092852 | 12161548 | 12161571 | 3 | + | 28162770 | P31FUJ | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | 0.3526415957410629 | [998] | [1498] | 4 | hSpCas9 | negative selection | 11092853 | 12151252 | 12151275 | 3 | + | 28162770 | P31FUJ | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | 0.08444940326351036 | [617] | [769] | 0 | hSpCas9 | negative selection | 11092854 | 12169780 | 12169803 | 3 | + | 28162770 | P31FUJ | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | 0.26628517233957893 | [945] | [1336] | 3 | hSpCas9 | negative selection | 11092855 | 12004877 | 12004900 | 3 | - | 28162770 | P31FUJ | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | 0.11176856709424854 | [1630] | [2070] | 1 | hSpCas9 | negative selection | 11092856 | 12141937 | 12141960 | 3 | + | 28162770 | P31FUJ | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | 0.6143889523062291 | [795] | [1431] | 7 | hSpCas9 | negative selection | 11092857 | 12145709 | 12145732 | 3 | + | 28162770 | P31FUJ | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | 0.5931236645481586 | [1653] | [2931] | 6 | hSpCas9 | negative selection | 11092858 | 12145745 | 12145768 | 3 | - | 28162770 | P31FUJ | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | 0.2941147671757969 | [802] | [1156] | 3 | hSpCas9 | negative selection | 11092859 | 12145778 | 12145801 | 3 | - | 28162770 | P31FUJ | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.3777520102095182 | [1489] | [2274] | 4 | hSpCas9 | negative selection | 11092860 | 12004613 | 12004636 | 3 | + | 28162770 | OCIAML5 | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | 0.3377579880160201 | [95] | [218] | 3 | hSpCas9 | negative selection | 11262218 | 12161548 | 12161571 | 3 | + | 28162770 | OCIAML5 | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | -0.3215518541652169 | [161] | [233] | -2 | hSpCas9 | negative selection | 11262219 | 12151252 | 12151275 | 3 | + | 28162770 | OCIAML5 | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | 1.807096871698576 | [59] | [378] | 9 | hSpCas9 | negative selection | 11262220 | 12169780 | 12169803 | 3 | + | 28162770 | OCIAML5 | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | 0.4119950297735245 | [116] | [280] | 3 | hSpCas9 | negative selection | 11262221 | 12004877 | 12004900 | 3 | - | 28162770 | OCIAML5 | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | 0.45474023699870236 | [210] | [521] | 4 | hSpCas9 | negative selection | 11262222 | 12141937 | 12141960 | 3 | + | 28162770 | OCIAML5 | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | -0.5389086856043667 | [98] | [122] | -4 | hSpCas9 | negative selection | 11262223 | 12145709 | 12145732 | 3 | + | 28162770 | OCIAML5 | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | -0.05912733844445439 | [272] | [472] | 0 | hSpCas9 | negative selection | 11262224 | 12145745 | 12145768 | 3 | - | 28162770 | OCIAML5 | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | 0.6389197816481454 | [110] | [311] | 5 | hSpCas9 | negative selection | 11262225 | 12145778 | 12145801 | 3 | - | 28162770 | OCIAML5 | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.20269923256689493 | [167] | [348] | 1 | hSpCas9 | negative selection | 11262226 | 12004613 | 12004636 | 3 | + | 28162770 | EOL1 | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | -0.742583270731448 | [288] | [90] | -5 | hSpCas9 | negative selection | 11431584 | 12161548 | 12161571 | 3 | + | 28162770 | EOL1 | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | -0.10939956035280324 | [386] | [188] | -1 | hSpCas9 | negative selection | 11431585 | 12151252 | 12151275 | 3 | + | 28162770 | EOL1 | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | 0.21544897083727232 | [187] | [114] | 2 | hSpCas9 | negative selection | 11431586 | 12169780 | 12169803 | 3 | + | 28162770 | EOL1 | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | 1.2203461346332434 | [311] | [382] | 8 | hSpCas9 | negative selection | 11431587 | 12004877 | 12004900 | 3 | - | 28162770 | EOL1 | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | -0.07282675902264213 | [548] | [274] | 0 | hSpCas9 | negative selection | 11431588 | 12141937 | 12141960 | 3 | + | 28162770 | EOL1 | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | 0.6098151780873761 | [249] | [200] | 5 | hSpCas9 | negative selection | 11431589 | 12145709 | 12145732 | 3 | + | 28162770 | EOL1 | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | 0.31801185890102646 | [538] | [353] | 3 | hSpCas9 | negative selection | 11431590 | 12145745 | 12145768 | 3 | - | 28162770 | EOL1 | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | 0.9128184789884275 | [246] | [244] | 7 | hSpCas9 | negative selection | 11431591 | 12145778 | 12145801 | 3 | - | 28162770 | EOL1 | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.9757018595206377 | [470] | [487] | 8 | hSpCas9 | negative selection | 11431592 | 12004613 | 12004636 | 3 | + | 28162770 | MOLM13 | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | -0.022638317318528278 | [339] | [241] | 0 | hSpCas9 | negative selection | 11600950 | 12161548 | 12161571 | 3 | + | 28162770 | MOLM13 | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | 0.09491594183227897 | [337] | [260] | 0 | hSpCas9 | negative selection | 11600951 | 12151252 | 12151275 | 3 | + | 28162770 | MOLM13 | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | 0.41325412496773317 | [295] | [284] | 3 | hSpCas9 | negative selection | 11600952 | 12169780 | 12169803 | 3 | + | 28162770 | MOLM13 | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | 1.181462157281566 | [285] | [468] | 8 | hSpCas9 | negative selection | 11600953 | 12004877 | 12004900 | 3 | - | 28162770 | MOLM13 | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | 0.5712000987868748 | [457] | [491] | 4 | hSpCas9 | negative selection | 11600954 | 12141937 | 12141960 | 3 | + | 28162770 | MOLM13 | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | -0.044316776741263345 | [260] | [182] | 0 | hSpCas9 | negative selection | 11600955 | 12145709 | 12145732 | 3 | + | 28162770 | MOLM13 | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | 1.202930098786293 | [449] | [748] | 8 | hSpCas9 | negative selection | 11600956 | 12145745 | 12145768 | 3 | - | 28162770 | MOLM13 | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | 1.1601054689774861 | [202] | [327] | 8 | hSpCas9 | negative selection | 11600957 | 12145778 | 12145801 | 3 | - | 28162770 | MOLM13 | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 1.0204304045733577 | [359] | [527] | 7 | hSpCas9 | negative selection | 11600958 | 12004613 | 12004636 | 3 | + | 28162770 | HEL | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | 0.14487490159189242 | [232] | [164] | 1 | hSpCas9 | negative selection | 11770316 | 12161548 | 12161571 | 3 | + | 28162770 | HEL | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | -0.7603260256124109 | [319] | [120] | -5 | hSpCas9 | negative selection | 11770317 | 12151252 | 12151275 | 3 | + | 28162770 | HEL | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | 0.8099747459150293 | [178] | [200] | 7 | hSpCas9 | negative selection | 11770318 | 12169780 | 12169803 | 3 | + | 28162770 | HEL | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | 1.091379861508733 | [243] | [332] | 8 | hSpCas9 | negative selection | 11770319 | 12004877 | 12004900 | 3 | - | 28162770 | HEL | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | 0.6001992870358318 | [412] | [400] | 5 | hSpCas9 | negative selection | 11770320 | 12141937 | 12141960 | 3 | + | 28162770 | HEL | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | 0.43237896615880594 | [198] | [171] | 3 | hSpCas9 | negative selection | 11770321 | 12145709 | 12145732 | 3 | + | 28162770 | HEL | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | 0.7930193042963991 | [418] | [464] | 7 | hSpCas9 | negative selection | 11770322 | 12145745 | 12145768 | 3 | - | 28162770 | HEL | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | -0.06251790243851098 | [224] | [137] | 0 | hSpCas9 | negative selection | 11770323 | 12145778 | 12145801 | 3 | - | 28162770 | HEL | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.3457570942432254 | [343] | [279] | 3 | hSpCas9 | negative selection | 11770324 | 12004613 | 12004636 | 3 | + | 28162770 | MV411 | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | 0.00974599306344473 | [157] | [133] | 0 | hSpCas9 | negative selection | 11939682 | 12161548 | 12161571 | 3 | + | 28162770 | MV411 | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | -0.06606192203400624 | [255] | [205] | 0 | hSpCas9 | negative selection | 11939683 | 12151252 | 12151275 | 3 | + | 28162770 | MV411 | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | 1.155243852573029 | [104] | [196] | 8 | hSpCas9 | negative selection | 11939684 | 12169780 | 12169803 | 3 | + | 28162770 | MV411 | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | 0.6893702771246795 | [278] | [378] | 6 | hSpCas9 | negative selection | 11939685 | 12004877 | 12004900 | 3 | - | 28162770 | MV411 | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | 0.5768993183555451 | [381] | [479] | 5 | hSpCas9 | negative selection | 11939686 | 12141937 | 12141960 | 3 | + | 28162770 | MV411 | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | 0.12642214982140937 | [173] | [159] | 1 | hSpCas9 | negative selection | 11939687 | 12145709 | 12145732 | 3 | + | 28162770 | MV411 | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | 0.8041230611228389 | [394] | [580] | 7 | hSpCas9 | negative selection | 11939688 | 12145745 | 12145768 | 3 | - | 28162770 | MV411 | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | 0.49897631777873974 | [209] | [249] | 4 | hSpCas9 | negative selection | 11939689 | 12145778 | 12145801 | 3 | - | 28162770 | MV411 | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.3702099329040709 | [348] | [379] | 3 | hSpCas9 | negative selection | 11939690 | 12004613 | 12004636 | 3 | + | 28162770 | MONOMAC1 | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | -0.5766255103341075 | [133] | [102] | -5 | hSpCas9 | negative selection | 12109048 | 12161548 | 12161571 | 3 | + | 28162770 | MONOMAC1 | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | 0.741562608276303 | [143] | [275] | 7 | hSpCas9 | negative selection | 12109049 | 12151252 | 12151275 | 3 | + | 28162770 | MONOMAC1 | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | -0.023705244173992 | [93] | [105] | 0 | hSpCas9 | negative selection | 12109050 | 12169780 | 12169803 | 3 | + | 28162770 | MONOMAC1 | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | 0.8666217901627641 | [132] | [277] | 7 | hSpCas9 | negative selection | 12109051 | 12004877 | 12004900 | 3 | - | 28162770 | MONOMAC1 | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | -0.7136123728004597 | [308] | [215] | -5 | hSpCas9 | negative selection | 12109052 | 12141937 | 12141960 | 3 | + | 28162770 | MONOMAC1 | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | -0.23325703497230701 | [120] | [117] | -2 | hSpCas9 | negative selection | 12109053 | 12145709 | 12145732 | 3 | + | 28162770 | MONOMAC1 | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | 0.6706233870866183 | [250] | [457] | 6 | hSpCas9 | negative selection | 12109054 | 12145745 | 12145768 | 3 | - | 28162770 | MONOMAC1 | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | 0.2992680338412058 | [150] | [212] | 3 | hSpCas9 | negative selection | 12109055 | 12145778 | 12145801 | 3 | - | 28162770 | MONOMAC1 | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.5293336318674533 | [245] | [406] | 5 | hSpCas9 | negative selection | 12109056 | 12004613 | 12004636 | 3 | + | 28162770 | OCIAML2 | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | -0.11307782062407762 | [47] | [245] | -1 | hSpCas9 | negative selection | 12278414 | 12161548 | 12161571 | 3 | + | 28162770 | OCIAML2 | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | 0.5226755221838305 | [53] | [429] | 5 | hSpCas9 | negative selection | 12278415 | 12151252 | 12151275 | 3 | + | 28162770 | OCIAML2 | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | -0.4311014610555237 | [35] | [147] | -3 | hSpCas9 | negative selection | 12278416 | 12169780 | 12169803 | 3 | + | 28162770 | OCIAML2 | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | 0.46225597889930187 | [43] | [335] | 4 | hSpCas9 | negative selection | 12278417 | 12004877 | 12004900 | 3 | - | 28162770 | OCIAML2 | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | 0.9516031754408865 | [49] | [535] | 8 | hSpCas9 | negative selection | 12278418 | 12141937 | 12141960 | 3 | + | 28162770 | OCIAML2 | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | 0.7249209838756456 | [30] | [283] | 7 | hSpCas9 | negative selection | 12278419 | 12145709 | 12145732 | 3 | + | 28162770 | OCIAML2 | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | 1.031870515287022 | [65] | [747] | 8 | hSpCas9 | negative selection | 12278420 | 12145745 | 12145768 | 3 | - | 28162770 | OCIAML2 | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | -0.13131965212656233 | [32] | [166] | -1 | hSpCas9 | negative selection | 12278421 | 12145778 | 12145801 | 3 | - | 28162770 | OCIAML2 | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.5449670298088573 | [68] | [557] | 5 | hSpCas9 | negative selection | 12278422 | 12004613 | 12004636 | 3 | + | 28162770 | OCIAML3 | viability | GCTACATGACCGACCTGCAGCGG | SYN2 | ENSG00000157152 | 0.17152710603881377 | [39] | [135] | 1 | hSpCas9 | negative selection | 12447780 | 12161548 | 12161571 | 3 | + | 28162770 | OCIAML3 | viability | GACACTGCCCACGTTCCCTGTGG | SYN2 | ENSG00000157152 | -0.5608407763889638 | [85] | [175] | -4 | hSpCas9 | negative selection | 12447781 | 12151252 | 12151275 | 3 | + | 28162770 | OCIAML3 | viability | GCTATCTATAAGACACTGGGAGG | SYN2 | ENSG00000157152 | 0.5415073303323179 | [32] | [144] | 5 | hSpCas9 | negative selection | 12447782 | 12169780 | 12169803 | 3 | + | 28162770 | OCIAML3 | viability | GATTGGGGAACATCAGGTGGAGG | SYN2 | ENSG00000157152 | -0.9445048874082964 | [50] | [79] | -6 | hSpCas9 | negative selection | 12447783 | 12004877 | 12004900 | 3 | - | 28162770 | OCIAML3 | viability | CAGCACCTTGGCCTTCCTGGCGG | SYN2 | ENSG00000157152 | 0.4642517576482321 | [90] | [378] | 4 | hSpCas9 | negative selection | 12447784 | 12141937 | 12141960 | 3 | + | 28162770 | OCIAML3 | viability | TGCAGATGGCACCTATGCTGTGG | SYN2 | ENSG00000157152 | 0.5121917635077622 | [35] | [154] | 5 | hSpCas9 | negative selection | 12447785 | 12145709 | 12145732 | 3 | + | 28162770 | OCIAML3 | viability | GCAGCATGCATTTGGCATGGCGG | SYN2 | ENSG00000157152 | -0.09225850785198864 | [112] | [319] | 0 | hSpCas9 | negative selection | 12447786 | 12145745 | 12145768 | 3 | - | 28162770 | OCIAML3 | viability | GCATACCAATGATCAGGTGGCGG | SYN2 | ENSG00000157152 | 1.6488488835720003 | [29] | [283] | 9 | hSpCas9 | negative selection | 12447787 | 12145778 | 12145801 | 3 | - | 28162770 | OCIAML3 | viability | CCAGTGAGTTGATGCTGGGGAGG | SYN2 | ENSG00000157152 | 0.6828325650346612 | [103] | [503] | 6 | hSpCas9 | negative selection | 12447788 |