Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6855
• Symbol:Syp
• Description:synaptophysin

DataSource: http://genomecrispr.dkfz.de/#!/results/Syp

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
49193416	49193439	X	+	26472758	Jiyoye	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	0.7941985046151205	[38]	[50]	5	hSpCas9	negative selection	159802
49194241	49194264	X	+	26472758	Jiyoye	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.932266426249631	[163]	[235]	6	hSpCas9	negative selection	159803
49193431	49193454	X	+	26472758	Jiyoye	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	-0.47253038477641485	[45]	[24]	-3	hSpCas9	negative selection	159804
49197810	49197833	X	+	26472758	Jiyoye	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	0.8092738250772189	[27]	[36]	5	hSpCas9	negative selection	159805
49197796	49197819	X	-	26472758	Jiyoye	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	-0.02722744263990151	[149]	[110]	0	hSpCas9	negative selection	159806
49194323	49194346	X	-	26472758	Jiyoye	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.024163930102071074	[177]	[131]	0	hSpCas9	negative selection	159807
49194292	49194315	X	+	26472758	Jiyoye	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	-0.48165524255765413	[386]	[208]	-3	hSpCas9	negative selection	159808
49193416	49193439	X	+	26472758	KBM7	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	-0.008637144403388752	[314,364]	[115,200]	0	hSpCas9	negative selection	350920
49194241	49194264	X	+	26472758	KBM7	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.5187095756556983	[905,714]	[644,449]	5	hSpCas9	negative selection	350921
49193431	49193454	X	+	26472758	KBM7	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	0.05275083604600894	[109,83]	[48,44]	0	hSpCas9	negative selection	350922
49197810	49197833	X	+	26472758	KBM7	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	1.345671826208962	[177,240]	[105,388]	9	hSpCas9	negative selection	350923
49197796	49197819	X	-	26472758	KBM7	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.3649659409464967	[342,244]	[187,164]	4	hSpCas9	negative selection	350924
49194323	49194346	X	-	26472758	KBM7	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.6529932776388128	[946,700]	[727,490]	7	hSpCas9	negative selection	350925
49194292	49194315	X	+	26472758	KBM7	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	-0.07891338274769133	[1741,1440]	[684,722]	-1	hSpCas9	negative selection	350926
49193416	49193439	X	+	26472758	Raji	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	-0.3055554980212464	[228]	[42]	-3	hSpCas9	negative selection	542038
49194241	49194264	X	+	26472758	Raji	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.9147384574312036	[319]	[139]	8	hSpCas9	negative selection	542039
49193431	49193454	X	+	26472758	Raji	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	0.9057496742039488	[22]	[9]	8	hSpCas9	negative selection	542040
49197810	49197833	X	+	26472758	Raji	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	1.5390997757990736	[42]	[28]	9	hSpCas9	negative selection	542041
49197796	49197819	X	-	26472758	Raji	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	-0.3616129472992317	[226]	[40]	-3	hSpCas9	negative selection	542042
49194323	49194346	X	-	26472758	Raji	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.4508085654916044	[412]	[130]	4	hSpCas9	negative selection	542043
49194292	49194315	X	+	26472758	Raji	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.5387228469815437	[791]	[266]	5	hSpCas9	negative selection	542044
49193416	49193439	X	+	26472758	K562	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	0.07776885825699542	[274]	[244]	0	hSpCas9	negative selection	733156
49194241	49194264	X	+	26472758	K562	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	1.037567157225777	[553]	[959]	8	hSpCas9	negative selection	733157
49193431	49193454	X	+	26472758	K562	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	1.5800217594508856	[41]	[105]	9	hSpCas9	negative selection	733158
49197810	49197833	X	+	26472758	K562	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	0.9196553320809467	[190]	[304]	7	hSpCas9	negative selection	733159
49197796	49197819	X	-	26472758	K562	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.14223833285996879	[350]	[326]	1	hSpCas9	negative selection	733160
49194323	49194346	X	-	26472758	K562	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.1596432316710068	[770]	[726]	1	hSpCas9	negative selection	733161
49194292	49194315	X	+	26472758	K562	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	-0.399640406104236	[1332]	[852]	-3	hSpCas9	negative selection	733162
49191483	49191506	X	-	26627737	DLD1	viability	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	0.18604048666998418	[848]	[442,350,138]	2	hSpCas9	negative selection	845924
49193400	49193423	X	-	26627737	DLD1	viability	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.2066641499704819	[431]	[170,175,125]	2	hSpCas9	negative selection	845925
49194265	49194288	X	+	26627737	DLD1	viability	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.7102987193151648	[232]	[58,64,14]	-6	hSpCas9	negative selection	845926
49197622	49197645	X	+	26627737	DLD1	viability	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	0.2170023182930063	[1162]	[238,531,490]	2	hSpCas9	negative selection	845927
49191483	49191506	X	-	26627737	GBM cells	viability after 5 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	-0.13671003484503552	[368]	[181,177]	-2	hSpCas9	negative selection	928239
49193400	49193423	X	-	26627737	GBM cells	viability after 5 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.708436633626	[189]	[140,191]	8	hSpCas9	negative selection	928240
49194265	49194288	X	+	26627737	GBM cells	viability after 5 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.37098231920090846	[154]	[101,112]	5	hSpCas9	negative selection	928241
49197622	49197645	X	+	26627737	GBM cells	viability after 5 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.2919084674498925	[564]	[251,242]	-4	hSpCas9	negative selection	928242
49191483	49191506	X	-	26627737	GBM cells	viability after 13 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	-0.16043255007501184	[368]	[257,114]	-2	hSpCas9	negative selection	1010554
49193400	49193423	X	-	26627737	GBM cells	viability after 13 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.7694473066805149	[189]	[183,168]	8	hSpCas9	negative selection	1010555
49194265	49194288	X	+	26627737	GBM cells	viability after 13 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.07833891727633346	[154]	[77,80]	-1	hSpCas9	negative selection	1010556
49197622	49197645	X	+	26627737	GBM cells	viability after 13 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.5626274803212927	[564]	[222,194]	-6	hSpCas9	negative selection	1010557
49191483	49191506	X	-	26627737	GBM cells	viability after 21 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	-0.22985997955350512	[368]	[183,158]	-2	hSpCas9	negative selection	1092869
49193400	49193423	X	-	26627737	GBM cells	viability after 21 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.775082257525558	[189]	[184,168]	7	hSpCas9	negative selection	1092870
49194265	49194288	X	+	26627737	GBM cells	viability after 21 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.21685455157611516	[154]	[100,94]	2	hSpCas9	negative selection	1092871
49197622	49197645	X	+	26627737	GBM cells	viability after 21 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.3715081357856247	[564]	[230,242]	-3	hSpCas9	negative selection	1092872
49191483	49191506	X	-	26627737	RPE1	viability after 9 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	-0.4609756953026968	[1885]	[407,455]	-3	hSpCas9	negative selection	1175184
49193400	49193423	X	-	26627737	RPE1	viability after 9 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.6382742211019579	[731]	[388,314]	4	hSpCas9	negative selection	1175185
49194265	49194288	X	+	26627737	RPE1	viability after 9 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.7123474186239578	[859]	[231,76]	-5	hSpCas9	negative selection	1175186
49197622	49197645	X	+	26627737	RPE1	viability after 9 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	0.25852866575695965	[1466]	[689,367]	1	hSpCas9	negative selection	1175187
49191483	49191506	X	-	26627737	RPE1	viability after 12 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	-0.37366152145751197	[1885]	[393,387]	-3	hSpCas9	negative selection	1257499
49193400	49193423	X	-	26627737	RPE1	viability after 12 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.39706070226464446	[731]	[291,223]	2	hSpCas9	negative selection	1257500
49194265	49194288	X	+	26627737	RPE1	viability after 12 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-1.1394070557617413	[859]	[151,54]	-7	hSpCas9	negative selection	1257501
49197622	49197645	X	+	26627737	RPE1	viability after 12 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.41713247325135977	[1466]	[317,270]	-3	hSpCas9	negative selection	1257502
49191483	49191506	X	-	26627737	RPE1	viability after 15 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	-0.14757320228031734	[1885]	[445,515]	-1	hSpCas9	negative selection	1339814
49193400	49193423	X	-	26627737	RPE1	viability after 15 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.8433377227788406	[731]	[482,263]	5	hSpCas9	negative selection	1339815
49194265	49194288	X	+	26627737	RPE1	viability after 15 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.7826163929881513	[859]	[145,136]	-5	hSpCas9	negative selection	1339816
49197622	49197645	X	+	26627737	RPE1	viability after 15 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.046063711577196687	[1466]	[348,452]	0	hSpCas9	negative selection	1339817
49191483	49191506	X	-	26627737	RPE1	viability after 18 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	-0.18148331849099697	[1885]	[486,407]	-1	hSpCas9	negative selection	1422129
49193400	49193423	X	-	26627737	RPE1	viability after 18 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.34218477589978724	[731]	[320,174]	2	hSpCas9	negative selection	1422130
49194265	49194288	X	+	26627737	RPE1	viability after 18 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.7813038690427887	[859]	[208,55]	-5	hSpCas9	negative selection	1422131
49197622	49197645	X	+	26627737	RPE1	viability after 18 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	0.05317764563828853	[1466]	[432,386]	0	hSpCas9	negative selection	1422132
49191483	49191506	X	-	26627737	HeLa	viability after 8 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	1.34948291642357	[319]	[483,314,297]	8	hSpCas9	negative selection	1504444
49193400	49193423	X	-	26627737	HeLa	viability after 8 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.8069772982538423	[270]	[81,368,144]	6	hSpCas9	negative selection	1504445
49194265	49194288	X	+	26627737	HeLa	viability after 8 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.829614341784618	[324]	[198,15,51]	-7	hSpCas9	negative selection	1504446
49197622	49197645	X	+	26627737	HeLa	viability after 8 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.91840700141846	[2245]	[616,390,561]	-7	hSpCas9	negative selection	1504447
49191483	49191506	X	-	26627737	HeLa	viability after 12 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	1.3753131439404296	[319]	[339,249,448]	8	hSpCas9	negative selection	1586759
49193400	49193423	X	-	26627737	HeLa	viability after 12 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	1.0623574353863656	[270]	[274,222,205]	7	hSpCas9	negative selection	1586760
49194265	49194288	X	+	26627737	HeLa	viability after 12 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.49931424797276025	[324]	[132,20,139]	-4	hSpCas9	negative selection	1586761
49197622	49197645	X	+	26627737	HeLa	viability after 12 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-1.3152015906943828	[2245]	[495,274,361]	-8	hSpCas9	negative selection	1586762
49191483	49191506	X	-	26627737	HeLa	viability after 15 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	1.808160759229588	[319]	[73,354,984]	9	hSpCas9	negative selection	1669074
49193400	49193423	X	-	26627737	HeLa	viability after 15 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	1.2528591866934138	[270]	[136,382,270]	8	hSpCas9	negative selection	1669075
49194265	49194288	X	+	26627737	HeLa	viability after 15 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.19954093058885508	[324]	[51,196,95]	-2	hSpCas9	negative selection	1669076
49197622	49197645	X	+	26627737	HeLa	viability after 15 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.9294545783628823	[2245]	[659,429,336]	-7	hSpCas9	negative selection	1669077
49191483	49191506	X	-	26627737	HeLa	viability after 18 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	1.8252742395637078	[319]	[52,302,984]	9	hSpCas9	negative selection	1751389
49193400	49193423	X	-	26627737	HeLa	viability after 18 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	1.2584069847855268	[270]	[89,321,270]	8	hSpCas9	negative selection	1751390
49194265	49194288	X	+	26627737	HeLa	viability after 18 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.19431779732609072	[324]	[34,163,95]	-2	hSpCas9	negative selection	1751391
49197622	49197645	X	+	26627737	HeLa	viability after 18 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.9351502226707475	[2245]	[443,349,336]	-7	hSpCas9	negative selection	1751392
49191483	49191506	X	-	26627737	HCT116	viability after 6 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	1.5752892633300457	[1249]	[252,768]	7	hSpCas9	negative selection	1833704
49193400	49193423	X	-	26627737	HCT116	viability after 6 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	-0.4702373992163482	[572]	[55,69]	-3	hSpCas9	negative selection	1833705
49194265	49194288	X	+	26627737	HCT116	viability after 6 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-1.497109923914257	[437]	[64,1]	-7	hSpCas9	negative selection	1833706
49197622	49197645	X	+	26627737	HCT116	viability after 6 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.6296659941588292	[2643]	[646,59]	-4	hSpCas9	negative selection	1833707
49191483	49191506	X	-	26627737	HCT116	viability after 8 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	0.46405558276573033	[346]	[231,237,319]	5	hSpCas9	negative selection	1916019
49193400	49193423	X	-	26627737	HCT116	viability after 8 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.2660735239458926	[245]	[161,163,162]	3	hSpCas9	negative selection	1916020
49194265	49194288	X	+	26627737	HCT116	viability after 8 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.769985298364541	[60]	[47,83,39]	7	hSpCas9	negative selection	1916021
49197622	49197645	X	+	26627737	HCT116	viability after 8 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.43126498109807443	[1049]	[572,385,331]	-5	hSpCas9	negative selection	1916022
49191483	49191506	X	-	26627737	HCT116	viability after 9 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	0.8625945837750997	[1249]	[459,722]	6	hSpCas9	negative selection	1998334
49193400	49193423	X	-	26627737	HCT116	viability after 9 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	-0.017878243027155155	[572]	[87,200]	0	hSpCas9	negative selection	1998335
49194265	49194288	X	+	26627737	HCT116	viability after 9 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.0204259409829885	[437]	[188,62]	0	hSpCas9	negative selection	1998336
49197622	49197645	X	+	26627737	HCT116	viability after 9 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-1.2515187707937032	[2643]	[219,356]	-7	hSpCas9	negative selection	1998337
49191483	49191506	X	-	26627737	HCT116	viability after 12 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	0.4632096180602162	[346]	[205,284,267]	4	hSpCas9	negative selection	2080649
49193400	49193423	X	-	26627737	HCT116	viability after 12 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.6380779857681289	[245]	[62,212,339]	6	hSpCas9	negative selection	2080650
49194265	49194288	X	+	26627737	HCT116	viability after 12 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	1.050609026230431	[60]	[91,67,36]	8	hSpCas9	negative selection	2080651
49197622	49197645	X	+	26627737	HCT116	viability after 12 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.19465035944076936	[1049]	[453,566,429]	-2	hSpCas9	negative selection	2080652
49191483	49191506	X	-	26627737	HCT116	viability after 15 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	0.4512007365981181	[346]	[272,319,224]	4	hSpCas9	negative selection	2162964
49193400	49193423	X	-	26627737	HCT116	viability after 15 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.4997566030980023	[245]	[126,310,152]	5	hSpCas9	negative selection	2162965
49194265	49194288	X	+	26627737	HCT116	viability after 15 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	1.15319179263027	[60]	[95,66,72]	8	hSpCas9	negative selection	2162966
49197622	49197645	X	+	26627737	HCT116	viability after 15 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.30447495193884677	[1049]	[729,503,262]	-3	hSpCas9	negative selection	2162967
49191483	49191506	X	-	26627737	HCT116	viability after 18 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	0.49282601380392654	[346]	[198,312,188]	4	hSpCas9	negative selection	2245279
49193400	49193423	X	-	26627737	HCT116	viability after 18 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.4840129828073607	[245]	[57,287,143]	4	hSpCas9	negative selection	2245280
49194265	49194288	X	+	26627737	HCT116	viability after 18 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	2.260295860217808	[60]	[100,207,108]	9	hSpCas9	negative selection	2245281
49197622	49197645	X	+	26627737	HCT116	viability after 18 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.8750964772980229	[1049]	[184,453,174]	-7	hSpCas9	negative selection	2245282
49194859	49194882	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGCGTAGCGG	SYP	ENSG00000102003	-0.9180937029961482	[133,53]	[15,3]	-5	dCas9-VP64	positive selection	2404996
49194859	49194882	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGCGTAGCGG	SYP	ENSG00000102003	0.01566490298595924	[8,84]	[11,17]	0	dCas9-VP64	positive selection	2500251
49193432	49193455	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	-0.06904083953230214	[3,3]	[2,1]	-1	hSpCas9	positive selection	3024966
49193448	49193471	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCTTAGGACTTTCTGGCCACGG	SYP	ENSG00000102003	-0.9584862900729547	[2,2]	[1,0]	-9	hSpCas9	positive selection	3024967
49193432	49193455	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	-0.49539266886733135	[3,3]	[3,0]	-7	hSpCas9	positive selection	3092824
49193448	49193471	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCTTAGGACTTTCTGGCCACGG	SYP	ENSG00000102003	0.7267255284659979	[2,2]	[1,3]	9	hSpCas9	positive selection	3092825
49193272	49193295		+	24336571	A375	resistance to PLX after 7 days	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.2676012021248805	[6,5]	[4,5]	-7	hSpCas9	positive selection	3148649
49193272	49193295		+	24336571	A375	resistance to PLX after 14 days	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	0.5886533996318499	[3,5]	[2,4]	5	hSpCas9	positive selection	3206442
49193272	49193295		+	24336571	A375	viability after 7 days	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	0.23380320265390553	[5]	[6,5]	3	hSpCas9	negative selection	3264235
49193272	49193295		+	24336571	A375	viability after 14 days	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	0.019844833723548394	[5]	[3,5]	0	hSpCas9	negative selection	3322028
49194258	49194281	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	-0.37929840909781365	[198,198]	[0,0]	-2	hSpCas9	positive selection	3395903
49194323	49194346	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.9025451253325543	[285,285]	[0,0]	-6	hSpCas9	positive selection	3395904
49193412	49193435	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.8974918976062689	[284,284]	[0,0]	-6	hSpCas9	positive selection	3395905
49193431	49193454	X	+	26780180	HT29	viability (Avana library 4 designs)	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	2.65280445252088	[]	[]	8	hSpCas9	negative selection	3463679
49193448	49193471	X	-	26780180	HT29	viability (Avana library 4 designs)	GCCTTAGGACTTTCTGGCCACGG	SYP	ENSG00000102003	1.51079828479496	[]	[]	6	hSpCas9	negative selection	3463680
49193431	49193454	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	4.43644871276673	[]	[]	7	hSpCas9	negative selection	3565831
49193448	49193471	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTTAGGACTTTCTGGCCACGG	SYP	ENSG00000102003	3.07900508962402	[]	[]	5	hSpCas9	negative selection	3565832
49194175	49194198	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTACCGAGAGAATAACAAAGGG	SYP	ENSG00000102003	-8.93391180237504	[]	[]	-7	hSpCas9	negative selection	3565833
49193431	49193454	X	+	26780180	A375	viability (Avana lentiGuide)	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	3.75361074721055	[]	[]	3	hSpCas9	negative selection	3674490
49193448	49193471	X	-	26780180	A375	viability (Avana lentiGuide)	GCCTTAGGACTTTCTGGCCACGG	SYP	ENSG00000102003	-6.00630747640585	[]	[]	-8	hSpCas9	negative selection	3674491
49194175	49194198	X	-	26780180	A375	viability (Avana lentiGuide)	AGTACCGAGAGAATAACAAAGGG	SYP	ENSG00000102003	-3.20420570834679	[]	[]	-5	hSpCas9	negative selection	3674492
49193431	49193454	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	0.028104760460117104	[4]	[5,3]	0	hSpCas9	positive selection	3783097
49193448	49193471	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTTAGGACTTTCTGGCCACGG	SYP	ENSG00000102003	0.25319995953895735	[4]	[5,5]	7	hSpCas9	positive selection	3783098
49194175	49194198	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTACCGAGAGAATAACAAAGGG	SYP	ENSG00000102003	-0.7805188087997268	[6]	[3,2]	-8	hSpCas9	positive selection	3783099
49193431	49193454	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	0.19867513548952914	[5]	[5,4]	5	hSpCas9	positive selection	3891704
49193448	49193471	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTTAGGACTTTCTGGCCACGG	SYP	ENSG00000102003	0.3057616255700665	[4]	[4,5]	8	hSpCas9	positive selection	3891705
49194175	49194198	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTACCGAGAGAATAACAAAGGG	SYP	ENSG00000102003	0.19894911854188788	[4]	[5,3]	5	hSpCas9	positive selection	3891706
49194258	49194281	X	-	26780180	A375	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	1.02794382037051	[]	[]	5	hSpCas9	negative selection	4001389
49193272	49193295	X	+	26780180	A375	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	0.42626246110747	[]	[]	1	hSpCas9	negative selection	4001390
49193412	49193435	X	-	26780180	A375	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	0.852725382578893	[]	[]	3	hSpCas9	negative selection	4001391
49197728	49197751	X	+	26780180	A375	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	-0.0259425080748242	[]	[]	-1	hSpCas9	negative selection	4001392
49197714	49197737	X	-	26780180	A375	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.774512081739164	[]	[]	3	hSpCas9	negative selection	4001393
49194323	49194346	X	-	26780180	A375	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.704461522585119	[]	[]	2	hSpCas9	negative selection	4001394
49194258	49194281	X	-	26780180	HT29	viability (GeCKOv2 library)	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.996923294862633	[]	[]	4	hSpCas9	negative selection	4109355
49193272	49193295	X	+	26780180	HT29	viability (GeCKOv2 library)	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	0.612075976263889	[]	[]	2	hSpCas9	negative selection	4109356
49193412	49193435	X	-	26780180	HT29	viability (GeCKOv2 library)	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	1.36048391334948	[]	[]	7	hSpCas9	negative selection	4109357
49197728	49197751	X	+	26780180	HT29	viability (GeCKOv2 library)	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	-0.544437931568287	[]	[]	-9	hSpCas9	negative selection	4109358
49197714	49197737	X	-	26780180	HT29	viability (GeCKOv2 library)	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	1.22488335578302	[]	[]	6	hSpCas9	negative selection	4109359
49194323	49194346	X	-	26780180	HT29	viability (GeCKOv2 library)	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.366921055401036	[]	[]	1	hSpCas9	negative selection	4109360
49193272	49193295	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.06629738149926018	[2]	[1,1]	-1	hSpCas9	positive selection	4174918
49193272	49193295	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	0.14434502071809363	[1]	[0,0,0,0]	1	hSpCas9	positive selection	4238940
49197728	49197751	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.2317892831105797	[3]	[3,2]	4	hSpCas9	positive selection	4301655
49197714	49197737	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.23950451639783152	[3]	[4,2]	5	hSpCas9	positive selection	4301656
49193272	49193295	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.26368230638588397	[0]	[0,0]	-5	hSpCas9	positive selection	4301657
49194258	49194281	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.38236275218328275	[2]	[3,2]	7	hSpCas9	positive selection	4365910
49194323	49194346	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.12218952526941772	[3]	[3,1]	-2	hSpCas9	positive selection	4365911
49193412	49193435	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	0.059643484304268246	[3]	[3,2]	1	hSpCas9	positive selection	4365912
49193406	49193428	X	-	27760321	OCIAML3	viability	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	0.21615597765852382	[519,478]	[326,618]	2	hSpCas9	negative selection	4444779
49194266	49194288	X	+	27760321	OCIAML3	viability	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.26339656856957455	[459,399]	[150,446]	-3	hSpCas9	negative selection	4444780
49194293	49194315	X	+	27760321	OCIAML3	viability	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	1.2501218633213096	[238,182]	[313,487]	9	hSpCas9	negative selection	4444781
49194323	49194345	X	-	27760321	OCIAML3	viability	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.7369957529159556	[1005,839]	[1024,1423]	8	hSpCas9	negative selection	4444782
49197701	49197723	X	+	27760321	OCIAML3	viability	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	-0.2696718335658577	[387,330]	[228,236]	-3	hSpCas9	negative selection	4444783
49193406	49193428	X	-	27760321	OCIAML2	viability	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	0.32779697959775256	[519,478]	[469,555]	4	hSpCas9	negative selection	4528242
49194266	49194288	X	+	27760321	OCIAML2	viability	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.5210362238032904	[459,399]	[380,651]	7	hSpCas9	negative selection	4528243
49194293	49194315	X	+	27760321	OCIAML2	viability	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.016809622116632505	[238,182]	[157,188]	0	hSpCas9	negative selection	4528244
49194323	49194345	X	-	27760321	OCIAML2	viability	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.6344080123180869	[1005,839]	[1004,1350]	8	hSpCas9	negative selection	4528245
49197701	49197723	X	+	27760321	OCIAML2	viability	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	-0.13789187599452968	[387,330]	[237,296]	-2	hSpCas9	negative selection	4528246
49193406	49193428	X	-	27760321	MV411	viability	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	0.7798859501916223	[519,478]	[696,368]	6	hSpCas9	negative selection	4611705
49194266	49194288	X	+	27760321	MV411	viability	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	1.0640555833298073	[459,399]	[387,897]	7	hSpCas9	negative selection	4611706
49194293	49194315	X	+	27760321	MV411	viability	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.35495883135158635	[238,182]	[85,312]	2	hSpCas9	negative selection	4611707
49194323	49194345	X	-	27760321	MV411	viability	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.11459679290139113	[1005,839]	[344,1124]	0	hSpCas9	negative selection	4611708
49197701	49197723	X	+	27760321	MV411	viability	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	0.23327489951368977	[387,330]	[241,331]	1	hSpCas9	negative selection	4611709
49193406	49193428	X	-	27760321	HL60	viability	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	-0.3414368295314745	[519,478]	[338,303]	-4	hSpCas9	negative selection	4695168
49194266	49194288	X	+	27760321	HL60	viability	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.09613548396455032	[459,399]	[375,372]	1	hSpCas9	negative selection	4695169
49194293	49194315	X	+	27760321	HL60	viability	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.4361928699668196	[238,182]	[278,180]	5	hSpCas9	negative selection	4695170
49194323	49194345	X	-	27760321	HL60	viability	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.33923366055324244	[1005,839]	[864,1039]	4	hSpCas9	negative selection	4695171
49197701	49197723	X	+	27760321	HL60	viability	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	-0.46748399605750796	[387,330]	[234,186]	-5	hSpCas9	negative selection	4695172
49193406	49193428	X	-	27760321	HT1080	viability	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	0.9726263985080333	[478,373]	[468,184]	5	hSpCas9	negative selection	4778631
49194266	49194288	X	+	27760321	HT1080	viability	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.335937663299093	[399,311]	[161,57]	-1	hSpCas9	negative selection	4778632
49194293	49194315	X	+	27760321	HT1080	viability	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.9531441694780833	[182,142]	[119,131]	5	hSpCas9	negative selection	4778633
49194323	49194345	X	-	27760321	HT1080	viability	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.6437145978889116	[839,655]	[466,463]	3	hSpCas9	negative selection	4778634
49197701	49197723	X	+	27760321	HT1080	viability	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	-1.0587802541151718	[330,257]	[83,25]	-4	hSpCas9	negative selection	4778635
49193406	49193428	X	-	27760321	HT29	viability after 7 days	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	-0.8065605002896239	[478,373]	[399,287,265]	-8	hSpCas9	negative selection	4862094
49194266	49194288	X	+	27760321	HT29	viability after 7 days	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.034511702623692186	[399,311]	[653,283,431]	0	hSpCas9	negative selection	4862095
49194293	49194315	X	+	27760321	HT29	viability after 7 days	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.32768639623668583	[182,142]	[267,244,275]	5	hSpCas9	negative selection	4862096
49194323	49194345	X	-	27760321	HT29	viability after 7 days	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.44890699381309385	[839,655]	[1423,1490,1045]	6	hSpCas9	negative selection	4862097
49197701	49197723	X	+	27760321	HT29	viability after 7 days	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	-0.170648951980032	[330,257]	[640,135,276]	-3	hSpCas9	negative selection	4862098
49193406	49193428	X	-	27760321	HT29	viability after 25 days	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	-0.08999007084648689	[478,373]	[397,485,496]	-1	hSpCas9	negative selection	4945557
49194266	49194288	X	+	27760321	HT29	viability after 25 days	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.05091897714072859	[399,311]	[286,478,515]	0	hSpCas9	negative selection	4945558
49194293	49194315	X	+	27760321	HT29	viability after 25 days	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.5275658675647171	[182,142]	[252,294,256]	6	hSpCas9	negative selection	4945559
49194323	49194345	X	-	27760321	HT29	viability after 25 days	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.29734929185188386	[839,655]	[904,1049,1221]	3	hSpCas9	negative selection	4945560
49197701	49197723	X	+	27760321	HT29	viability after 25 days	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	-0.028795272435840347	[330,257]	[269,288,445]	0	hSpCas9	negative selection	4945561
49193406	49193428	X	-	27760321	HT29	viability after 22 days	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	-0.2781874874034932	[478,373]	[356,364,499]	-3	hSpCas9	negative selection	5029020
49194266	49194288	X	+	27760321	HT29	viability after 22 days	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.14809965307197623	[399,311]	[294,560,516]	1	hSpCas9	negative selection	5029021
49194293	49194315	X	+	27760321	HT29	viability after 22 days	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.951159171956709	[182,142]	[310,365,417]	9	hSpCas9	negative selection	5029022
49194323	49194345	X	-	27760321	HT29	viability after 22 days	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.4373348711369356	[839,655]	[1177,1233,1099]	5	hSpCas9	negative selection	5029023
49197701	49197723	X	+	27760321	HT29	viability after 22 days	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	0.2698774816284986	[330,257]	[376,471,382]	3	hSpCas9	negative selection	5029024
49193406	49193428	X	-	27760321	HT29	viability after 19 days	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	-0.3276382527086364	[478,373]	[263,318,562]	-3	hSpCas9	negative selection	5112483
49194266	49194288	X	+	27760321	HT29	viability after 19 days	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.7461193397765098	[399,311]	[436,515,1054]	7	hSpCas9	negative selection	5112484
49194293	49194315	X	+	27760321	HT29	viability after 19 days	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	1.0664405624819528	[182,142]	[623,247,325]	9	hSpCas9	negative selection	5112485
49194323	49194345	X	-	27760321	HT29	viability after 19 days	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.7477120320150137	[839,655]	[1404,1564,1338]	7	hSpCas9	negative selection	5112486
49197701	49197723	X	+	27760321	HT29	viability after 19 days	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	0.15477388183149696	[330,257]	[537,453,157]	1	hSpCas9	negative selection	5112487
49193406	49193428	X	-	27760321	HT29	viability after 16 days	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	0.04068528566336255	[478,373]	[598,246,642]	0	hSpCas9	negative selection	5195946
49194266	49194288	X	+	27760321	HT29	viability after 16 days	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.1774622996732961	[399,311]	[313,460,562]	2	hSpCas9	negative selection	5195947
49194293	49194315	X	+	27760321	HT29	viability after 16 days	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	-0.12857187591498054	[182,142]	[169,80,251]	-1	hSpCas9	negative selection	5195948
49194323	49194345	X	-	27760321	HT29	viability after 16 days	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.574830101420843	[839,655]	[1238,1007,1497]	6	hSpCas9	negative selection	5195949
49197701	49197723	X	+	27760321	HT29	viability after 16 days	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	0.2940761454599125	[330,257]	[380,312,517]	3	hSpCas9	negative selection	5195950
49193406	49193428	X	-	27760321	HT29	viability after 13 days	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	-0.36543323255919696	[478,373]	[296,481,373]	-4	hSpCas9	negative selection	5279409
49194266	49194288	X	+	27760321	HT29	viability after 13 days	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.603097049655645	[399,311]	[793,452,633]	7	hSpCas9	negative selection	5279410
49194293	49194315	X	+	27760321	HT29	viability after 13 days	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.21067381412784947	[182,142]	[108,281,262]	2	hSpCas9	negative selection	5279411
49194323	49194345	X	-	27760321	HT29	viability after 13 days	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.49025456756907104	[839,655]	[1377,1240,1047]	6	hSpCas9	negative selection	5279412
49197701	49197723	X	+	27760321	HT29	viability after 13 days	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	0.18852291584913305	[330,257]	[312,481,373]	2	hSpCas9	negative selection	5279413
49193406	49193428	X	-	27760321	HT29	viability after 10 days	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	-0.3068382750128415	[478,373]	[389,359,536]	-4	hSpCas9	negative selection	5362872
49194266	49194288	X	+	27760321	HT29	viability after 10 days	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	-0.286191658659735	[399,311]	[439,181,463]	-4	hSpCas9	negative selection	5362873
49194293	49194315	X	+	27760321	HT29	viability after 10 days	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.33331523906409255	[182,142]	[194,258,313]	4	hSpCas9	negative selection	5362874
49194323	49194345	X	-	27760321	HT29	viability after 10 days	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.21245892578861336	[839,655]	[961,1050,1228]	3	hSpCas9	negative selection	5362875
49197701	49197723	X	+	27760321	HT29	viability after 10 days	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	-0.01117202801383299	[330,257]	[202,247,633]	0	hSpCas9	negative selection	5362876
49193406	49193428	X	-	27760321	MOLM13	viability	CTAGTTAGCTCATCGGCATGGG	SYP	ENSG00000102003	0.7887476137023972	[519,478]	[300,644]	5	hSpCas9	negative selection	5446335
49194266	49194288	X	+	27760321	MOLM13	viability	ACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.6646978723008535	[459,399]	[569,224]	4	hSpCas9	negative selection	5446336
49194293	49194315	X	+	27760321	MOLM13	viability	TCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	1.3735073449800674	[238,182]	[445,186]	8	hSpCas9	negative selection	5446337
49194323	49194345	X	-	27760321	MOLM13	viability	TTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	1.0895295423132738	[1005,839]	[1363,881]	7	hSpCas9	negative selection	5446338
49197701	49197723	X	+	27760321	MOLM13	viability	GGGTGGGAGCACACCTGAAGGG	SYP	ENSG00000102003	-0.14441963527584767	[387,330]	[62,284]	-1	hSpCas9	negative selection	5446339
49197728	49197751	X	+	27260156	BXPC3	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.4150311569707099	[666]	[786,915,887,1166]	8	hSpCas9	negative selection	5574115
49197714	49197737	X	-	27260156	BXPC3	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.18783256426426176	[701]	[868,869,723,871]	4	hSpCas9	negative selection	5574116
49193272	49193295	X	+	27260156	BXPC3	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.7344942960313263	[30]	[35,6,10,22]	-9	hSpCas9	negative selection	5574117
49194258	49194281	X	-	27260156	BXPC3	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.459282971376918	[372]	[547,482,555,558]	8	hSpCas9	negative selection	5638370
49194323	49194346	X	-	27260156	BXPC3	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.0059396216862983575	[741]	[755,713,664,978]	0	hSpCas9	negative selection	5638371
49193412	49193435	X	-	27260156	BXPC3	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.051021024165796014	[979]	[878,930,1085,1081]	-1	hSpCas9	negative selection	5638372
49197728	49197751	X	+	27260156	A673	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.43126154093824154	[666]	[1099,815,1189,1227]	8	hSpCas9	negative selection	5695366
49197714	49197737	X	-	27260156	A673	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.14678737440327438	[701]	[1081,941,705,1024]	3	hSpCas9	negative selection	5695367
49193272	49193295	X	+	27260156	A673	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	0.017661805375052797	[30]	[69,18,12,53]	0	hSpCas9	negative selection	5695368
49194258	49194281	X	-	27260156	A673	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.2614935304644379	[372]	[677,482,506,493]	6	hSpCas9	negative selection	5759621
49194323	49194346	X	-	27260156	A673	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.05955806144299358	[741]	[953,964,934,855]	1	hSpCas9	negative selection	5759622
49193412	49193435	X	-	27260156	A673	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.16806951703342476	[979]	[1132,991,1050,1020]	-4	hSpCas9	negative selection	5759623
49197728	49197751	X	+	27260156	A375	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.2876987149872632	[666]	[1209,890,1205,536]	4	hSpCas9	negative selection	5816617
49197714	49197737	X	-	27260156	A375	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.5180642610905164	[701]	[920,1411,1388,1019]	7	hSpCas9	negative selection	5816618
49193272	49193295	X	+	27260156	A375	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.06820029508441028	[30]	[9,55,41,32]	-1	hSpCas9	negative selection	5816619
49194258	49194281	X	-	27260156	A375	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.28820539468162226	[372]	[393,777,481,507]	4	hSpCas9	negative selection	5880872
49194323	49194346	X	-	27260156	A375	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.2737894858480011	[741]	[1294,936,1185,786]	4	hSpCas9	negative selection	5880873
49193412	49193435	X	-	27260156	A375	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	0.19077183934058084	[979]	[1288,1631,1039,1304]	2	hSpCas9	negative selection	5880874
49197728	49197751	X	+	27260156	COLO741	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.3528131488704658	[666]	[1245,1085,953]	7	hSpCas9	negative selection	5937868
49197714	49197737	X	-	27260156	COLO741	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.09706333627113639	[701]	[1127,970,802]	2	hSpCas9	negative selection	5937869
49193272	49193295	X	+	27260156	COLO741	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.3860983998759169	[30]	[26,52,11]	-7	hSpCas9	negative selection	5937870
49194258	49194281	X	-	27260156	COLO741	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.30100768302327224	[372]	[520,664,569]	6	hSpCas9	negative selection	6002123
49194323	49194346	X	-	27260156	COLO741	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.09519694138149992	[741]	[1130,975,943]	2	hSpCas9	negative selection	6002124
49193412	49193435	X	-	27260156	COLO741	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.1288696892105039	[979]	[1399,978,1079]	-3	hSpCas9	negative selection	6002125
49197728	49197751	X	+	27260156	CAL120	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.32010785954387466	[666]	[1242,1011,886]	5	hSpCas9	negative selection	6059119
49197714	49197737	X	-	27260156	CAL120	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.4916542072070873	[701]	[1255,1288,1144]	7	hSpCas9	negative selection	6059120
49193272	49193295	X	+	27260156	CAL120	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-1.698348582862094	[30]	[26,2,7]	-9	hSpCas9	negative selection	6059121
49194258	49194281	X	-	27260156	CAL120	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.3924302911254749	[372]	[676,735,427]	6	hSpCas9	negative selection	6123374
49194323	49194346	X	-	27260156	CAL120	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.1090270244824888	[741]	[844,1159,959]	1	hSpCas9	negative selection	6123375
49193412	49193435	X	-	27260156	CAL120	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.11388609679746842	[979]	[1158,1313,915]	-2	hSpCas9	negative selection	6123376
49197728	49197751	X	+	27260156	CADOES1	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.13610789361614006	[666]	[661,782,502,782]	2	hSpCas9	negative selection	6180370
49197714	49197737	X	-	27260156	CADOES1	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.3475347154291204	[701]	[738,651,1094,836]	6	hSpCas9	negative selection	6180371
49193272	49193295	X	+	27260156	CADOES1	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.7352153111960877	[30]	[24,6,25,10]	-8	hSpCas9	negative selection	6180372
49194258	49194281	X	-	27260156	CADOES1	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.46378857043396887	[372]	[397,668,302,546]	7	hSpCas9	negative selection	6244625
49194323	49194346	X	-	27260156	CADOES1	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.09743834188449929	[741]	[595,800,553,628]	-2	hSpCas9	negative selection	6244626
49193412	49193435	X	-	27260156	CADOES1	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.18113845070858037	[979]	[930,610,942,726]	-3	hSpCas9	negative selection	6244627
49197728	49197751	X	+	27260156	EWS502	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.5689089906275998	[666]	[929,1221,1095,939]	8	hSpCas9	negative selection	6301621
49197714	49197737	X	-	27260156	EWS502	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.3276268633718977	[701]	[885,931,843,1081]	6	hSpCas9	negative selection	6301622
49193272	49193295	X	+	27260156	EWS502	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-2.285376399073334	[30]	[6,7,1,9]	-9	hSpCas9	negative selection	6301623
49194258	49194281	X	-	27260156	EWS502	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.4166101390965743	[372]	[696,350,530,513]	7	hSpCas9	negative selection	6365876
49194323	49194346	X	-	27260156	EWS502	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.05430122824819095	[741]	[646,865,926,842]	0	hSpCas9	negative selection	6365877
49193412	49193435	X	-	27260156	EWS502	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.2131920102864574	[979]	[885,876,879,939]	-4	hSpCas9	negative selection	6365878
49197728	49197751	X	+	27260156	EW8	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	-0.14847452190842048	[666]	[647,376,472,470]	-3	hSpCas9	negative selection	6422872
49197714	49197737	X	-	27260156	EW8	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.26066695668015505	[701]	[734,560,803,608]	5	hSpCas9	negative selection	6422873
49193272	49193295	X	+	27260156	EW8	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.9253358544761028	[30]	[22,10,0,20]	-9	hSpCas9	negative selection	6422874
49194258	49194281	X	-	27260156	EW8	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.4660493958280743	[372]	[393,405,454,404]	8	hSpCas9	negative selection	6487127
49194323	49194346	X	-	27260156	EW8	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.038377028903983756	[741]	[630,604,403,735]	0	hSpCas9	negative selection	6487128
49193412	49193435	X	-	27260156	EW8	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.4142533607981117	[979]	[703,483,484,738]	-6	hSpCas9	negative selection	6487129
49197728	49197751	X	+	27260156	CORL105	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.2261690287569511	[666]	[924,749,1199,826]	4	hSpCas9	negative selection	6544123
49197714	49197737	X	-	27260156	CORL105	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.5207634991076813	[701]	[1247,1020,1247,1214]	8	hSpCas9	negative selection	6544124
49193272	49193295	X	+	27260156	CORL105	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-1.6806247787297988	[30]	[16,3,19,5]	-9	hSpCas9	negative selection	6544125
49194258	49194281	X	-	27260156	CORL105	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.6371550471686462	[372]	[677,696,641,692]	9	hSpCas9	negative selection	6608378
49194323	49194346	X	-	27260156	CORL105	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.13521622771038388	[741]	[944,843,1203,863]	2	hSpCas9	negative selection	6608379
49193412	49193435	X	-	27260156	CORL105	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.12548970827007788	[979]	[869,961,1002,1357]	-2	hSpCas9	negative selection	6608380
49197728	49197751	X	+	27260156	HS294T	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.3363177917385628	[666]	[267,281,344,430]	4	hSpCas9	negative selection	6665374
49197714	49197737	X	-	27260156	HS294T	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.47018430683934964	[701]	[316,390,398,405]	6	hSpCas9	negative selection	6665375
49193272	49193295	X	+	27260156	HS294T	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	0.024036926467315034	[30]	[0,19,23,2]	0	hSpCas9	negative selection	6665376
49194258	49194281	X	-	27260156	HS294T	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.7244933577456314	[372]	[210,165,214,390]	8	hSpCas9	negative selection	6729629
49194323	49194346	X	-	27260156	HS294T	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.04664581847225324	[741]	[296,281,312,291]	0	hSpCas9	negative selection	6729630
49193412	49193435	X	-	27260156	HS294T	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.30070802365514904	[979]	[237,345,307,349]	-4	hSpCas9	negative selection	6729631
49197728	49197751	X	+	27260156	HCC44	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.44638670437127836	[666]	[1071,803,1155,1125]	7	hSpCas9	negative selection	6786625
49197714	49197737	X	-	27260156	HCC44	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.3167070724954437	[701]	[1245,842,1058,859]	5	hSpCas9	negative selection	6786626
49193272	49193295	X	+	27260156	HCC44	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-1.9336845569090269	[30]	[6,0,12,16]	-9	hSpCas9	negative selection	6786627
49194258	49194281	X	-	27260156	HCC44	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.7038551156273913	[372]	[745,403,851,810]	9	hSpCas9	negative selection	6850880
49194323	49194346	X	-	27260156	HCC44	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.22119651971122245	[741]	[842,870,1157,1063]	3	hSpCas9	negative selection	6850881
49193412	49193435	X	-	27260156	HCC44	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.11881209593149422	[979]	[1178,1105,1000,794]	-2	hSpCas9	negative selection	6850882
49197728	49197751	X	+	27260156	G402	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.3281504333517644	[666]	[2056,700,839,634]	4	hSpCas9	negative selection	6907876
49197714	49197737	X	-	27260156	G402	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.5338399708981174	[701]	[1068,1544,972,1355]	6	hSpCas9	negative selection	6907877
49193272	49193295	X	+	27260156	G402	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	1.0319356223766412	[30]	[7,97,195,1]	9	hSpCas9	negative selection	6907878
49194258	49194281	X	-	27260156	G402	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.9839228098709429	[372]	[843,1365,501,903]	9	hSpCas9	negative selection	6972131
49194323	49194346	X	-	27260156	G402	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.18704748601764543	[741]	[1155,1269,738,987]	2	hSpCas9	negative selection	6972132
49193412	49193435	X	-	27260156	G402	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.23428562992475754	[979]	[821,1008,979,1212]	-3	hSpCas9	negative selection	6972133
49197728	49197751	X	+	27260156	L33	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.2643674811320814	[666]	[677,386,537,729]	5	hSpCas9	negative selection	7029127
49197714	49197737	X	-	27260156	L33	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.367044937171645	[701]	[836,380,634,846]	7	hSpCas9	negative selection	7029128
49193272	49193295	X	+	27260156	L33	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.9981341562741628	[30]	[20,3,13,8]	-9	hSpCas9	negative selection	7029129
49194258	49194281	X	-	27260156	L33	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.2273550047461089	[372]	[344,202,261,490]	5	hSpCas9	negative selection	7093382
49194323	49194346	X	-	27260156	L33	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.3058351965814471	[741]	[872,500,526,736]	6	hSpCas9	negative selection	7093383
49193412	49193435	X	-	27260156	L33	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.24763817686117318	[979]	[865,243,505,1031]	-5	hSpCas9	negative selection	7093384
49197728	49197751	X	+	27260156	K562	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.5692706214724669	[666]	[1409,897,830,463]	7	hSpCas9	negative selection	7150378
49197714	49197737	X	-	27260156	K562	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.6045129427972964	[701]	[1065,851,1192,706]	7	hSpCas9	negative selection	7150379
49193272	49193295	X	+	27260156	K562	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-2.4883847985991236	[30]	[0,9,7,0]	-9	hSpCas9	negative selection	7150380
49194258	49194281	X	-	27260156	K562	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.6852517217331129	[372]	[768,645,316,431]	8	hSpCas9	negative selection	7214633
49194323	49194346	X	-	27260156	K562	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.07532434911884289	[741]	[564,1044,473,450]	-1	hSpCas9	negative selection	7214634
49193412	49193435	X	-	27260156	K562	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.16319167201129225	[979]	[811,981,583,742]	-2	hSpCas9	negative selection	7214635
49197728	49197751	X	+	27260156	HT29	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.37458450264502874	[666]	[1297,1045,841,1031]	7	hSpCas9	negative selection	7271629
49197714	49197737	X	-	27260156	HT29	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.1794898174052557	[701]	[1237,922,956,780]	3	hSpCas9	negative selection	7271630
49193272	49193295	X	+	27260156	HT29	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	0.19431047571341153	[30]	[56,51,30,34]	4	hSpCas9	negative selection	7271631
49194258	49194281	X	-	27260156	HT29	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.01740956941680033	[372]	[356,452,527,482]	0	hSpCas9	negative selection	7335884
49194323	49194346	X	-	27260156	HT29	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.014447135682394752	[741]	[1145,1144,704,641]	0	hSpCas9	negative selection	7335885
49193412	49193435	X	-	27260156	HT29	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.13886823272539306	[979]	[1136,1188,1163,869]	-3	hSpCas9	negative selection	7335886
49197728	49197751	X	+	27260156	MHHES1	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.182587335660364	[666]	[943,1046,715,739]	3	hSpCas9	negative selection	7392880
49197714	49197737	X	-	27260156	MHHES1	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.3738713761102487	[701]	[1244,1191,1071,688]	6	hSpCas9	negative selection	7392881
49193272	49193295	X	+	27260156	MHHES1	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.6542559806835362	[30]	[19,34,5,26]	-8	hSpCas9	negative selection	7392882
49194258	49194281	X	-	27260156	MHHES1	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.6859577223128162	[372]	[746,808,661,526]	9	hSpCas9	negative selection	7457135
49194323	49194346	X	-	27260156	MHHES1	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.3982905546754659	[741]	[1191,993,1315,921]	7	hSpCas9	negative selection	7457136
49193412	49193435	X	-	27260156	MHHES1	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.2588114313401725	[979]	[1062,1254,626,800]	-5	hSpCas9	negative selection	7457137
49197728	49197751	X	+	27260156	MEWO	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.43535516395954144	[666]	[951,689,910]	8	hSpCas9	negative selection	7514131
49197714	49197737	X	-	27260156	MEWO	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.07518932611115037	[701]	[847,648,608]	1	hSpCas9	negative selection	7514132
49193272	49193295	X	+	27260156	MEWO	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.8821054997142657	[30]	[19,21,5]	-9	hSpCas9	negative selection	7514133
49194258	49194281	X	-	27260156	MEWO	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.19508732977257118	[372]	[509,357,351]	4	hSpCas9	negative selection	7578386
49194323	49194346	X	-	27260156	MEWO	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.08932959999510681	[741]	[886,612,502]	-2	hSpCas9	negative selection	7578387
49193412	49193435	X	-	27260156	MEWO	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.04007906512413517	[979]	[1074,788,846]	-1	hSpCas9	negative selection	7578388
49197728	49197751	X	+	27260156	LNCAPCLONEFGC	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.4761249492383658	[666]	[713,877,710,1038]	7	hSpCas9	negative selection	7635382
49197714	49197737	X	-	27260156	LNCAPCLONEFGC	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.457960899621378	[701]	[847,924,910,811]	7	hSpCas9	negative selection	7635383
49193272	49193295	X	+	27260156	LNCAPCLONEFGC	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.29849532791065236	[30]	[17,29,29,13]	-5	hSpCas9	negative selection	7635384
49194258	49194281	X	-	27260156	LNCAPCLONEFGC	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.534875131559724	[372]	[562,450,570,385]	8	hSpCas9	negative selection	7699637
49194323	49194346	X	-	27260156	LNCAPCLONEFGC	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.01646490311466653	[741]	[523,574,783,800]	0	hSpCas9	negative selection	7699638
49193412	49193435	X	-	27260156	LNCAPCLONEFGC	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.09375331596739367	[979]	[875,644,976,861]	-1	hSpCas9	negative selection	7699639
49197728	49197751	X	+	27260156	PANC0327	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.4212009594159408	[666]	[853,665,516,1156]	6	hSpCas9	negative selection	7756633
49197714	49197737	X	-	27260156	PANC0327	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.3983363917174846	[701]	[869,708,922,803]	6	hSpCas9	negative selection	7756634
49193272	49193295	X	+	27260156	PANC0327	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-1.7835247105739356	[30]	[22,1,6,1]	-9	hSpCas9	negative selection	7756635
49194258	49194281	X	-	27260156	PANC0327	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.5166417498392869	[372]	[745,449,266,457]	7	hSpCas9	negative selection	7820888
49194323	49194346	X	-	27260156	PANC0327	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.09719816178648955	[741]	[565,642,637,609]	-1	hSpCas9	negative selection	7820889
49193412	49193435	X	-	27260156	PANC0327	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	0.015301373431467313	[979]	[940,873,950,758]	0	hSpCas9	negative selection	7820890
49197728	49197751	X	+	27260156	NCIH2009	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.30559985688492186	[666]	[1359,1179,953]	4	hSpCas9	negative selection	7877884
49197714	49197737	X	-	27260156	NCIH2009	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.5129990315299569	[701]	[1511,1382,1323]	7	hSpCas9	negative selection	7877885
49193272	49193295	X	+	27260156	NCIH2009	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.5043532511426116	[30]	[52,29,12]	-6	hSpCas9	negative selection	7877886
49194258	49194281	X	-	27260156	NCIH2009	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.3080694825198403	[372]	[746,568,639]	4	hSpCas9	negative selection	7942139
49194323	49194346	X	-	27260156	NCIH2009	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.181282831565717	[741]	[1516,1229,843]	2	hSpCas9	negative selection	7942140
49193412	49193435	X	-	27260156	NCIH2009	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	0.07789435163309477	[979]	[1907,1309,1208]	1	hSpCas9	negative selection	7942141
49197728	49197751	X	+	27260156	NCIH1373	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.3655240506554578	[666]	[1480,867,605,260]	3	hSpCas9	negative selection	7999135
49197714	49197737	X	-	27260156	NCIH1373	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	1.0677717826692956	[701]	[2324,1860,1455,260]	9	hSpCas9	negative selection	7999136
49193272	49193295	X	+	27260156	NCIH1373	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-2.936561620912782	[30]	[7,2,3,0]	-9	hSpCas9	negative selection	7999137
49194258	49194281	X	-	27260156	NCIH1373	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.6593488934397602	[372]	[936,274,753,199]	6	hSpCas9	negative selection	8063390
49194323	49194346	X	-	27260156	NCIH1373	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.30680084047866873	[741]	[1176,984,1148,212]	3	hSpCas9	negative selection	8063391
49193412	49193435	X	-	27260156	NCIH1373	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.2579284250719195	[979]	[1027,591,601,405]	-3	hSpCas9	negative selection	8063392
49197728	49197751	X	+	27260156	PATU8902	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.8333411875004736	[666]	[1639,1570,1239,2346]	8	hSpCas9	negative selection	8120386
49197714	49197737	X	-	27260156	PATU8902	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.9132522237393086	[701]	[2767,1257,837,2853]	8	hSpCas9	negative selection	8120387
49193272	49193295	X	+	27260156	PATU8902	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	0.20263196219504476	[30]	[25,176,0,1]	2	hSpCas9	negative selection	8120388
49194258	49194281	X	-	27260156	PATU8902	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.9798499596930645	[372]	[887,962,1048,1206]	9	hSpCas9	negative selection	8184641
49194323	49194346	X	-	27260156	PATU8902	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.7568468066445181	[741]	[1614,2087,1062,2471]	7	hSpCas9	negative selection	8184642
49193412	49193435	X	-	27260156	PATU8902	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	0.57853254711414	[979]	[1808,2160,2453,1548]	6	hSpCas9	negative selection	8184643
49197728	49197751	X	+	27260156	PANC1	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.09019364021497989	[666]	[483,656,484,784]	1	hSpCas9	negative selection	8241637
49197714	49197737	X	-	27260156	PANC1	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.355345833273391	[701]	[748,1000,731,656]	6	hSpCas9	negative selection	8241638
49193272	49193295	X	+	27260156	PANC1	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-1.0376947930510916	[30]	[28,2,2,13]	-8	hSpCas9	negative selection	8241639
49194258	49194281	X	-	27260156	PANC1	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.22128500404533544	[372]	[479,391,354,277]	3	hSpCas9	negative selection	8305892
49194323	49194346	X	-	27260156	PANC1	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.23740598915429945	[741]	[594,1124,728,641]	4	hSpCas9	negative selection	8305893
49193412	49193435	X	-	27260156	PANC1	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	0.09948654581653793	[979]	[751,1073,1082,748]	1	hSpCas9	negative selection	8305894
49197728	49197751	X	+	27260156	PANC0813	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.4422924149819103	[666]	[1077,1149,1286,760]	7	hSpCas9	negative selection	8362888
49197714	49197737	X	-	27260156	PANC0813	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.7127754367017263	[701]	[1403,1570,1250,1190]	9	hSpCas9	negative selection	8362889
49193272	49193295	X	+	27260156	PANC0813	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.10873745468051332	[30]	[12,51,66,2]	-2	hSpCas9	negative selection	8362890
49194258	49194281	X	-	27260156	PANC0813	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.6475898289301913	[372]	[721,708,829,497]	8	hSpCas9	negative selection	8427143
49194323	49194346	X	-	27260156	PANC0813	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.05221242169320961	[741]	[1105,1045,688,795]	0	hSpCas9	negative selection	8427144
49193412	49193435	X	-	27260156	PANC0813	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	0.005128224602813702	[979]	[1416,1406,957,875]	0	hSpCas9	negative selection	8427145
49197728	49197751	X	+	27260156	RDES	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.5086287553188643	[666]	[885,1126,1180,1197]	7	hSpCas9	negative selection	8484139
49197714	49197737	X	-	27260156	RDES	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.3993111667877325	[701]	[889,1030,1240,1119]	6	hSpCas9	negative selection	8484140
49193272	49193295	X	+	27260156	RDES	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.4239039162054503	[30]	[32,33,18,14]	-6	hSpCas9	negative selection	8484141
49194258	49194281	X	-	27260156	RDES	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.27475600517473653	[372]	[394,475,582,661]	4	hSpCas9	negative selection	8548394
49194323	49194346	X	-	27260156	RDES	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.06104515121908416	[741]	[742,734,1220,894]	1	hSpCas9	negative selection	8548395
49193412	49193435	X	-	27260156	RDES	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.03266237162397889	[979]	[840,915,1333,1415]	0	hSpCas9	negative selection	8548396
49197728	49197751	X	+	27260156	PC3	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.5107140901411337	[666]	[767,669,1476,1064]	9	hSpCas9	negative selection	8605390
49197714	49197737	X	-	27260156	PC3	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.008316053834385162	[701]	[561,572,1253,621]	0	hSpCas9	negative selection	8605391
49193272	49193295	X	+	27260156	PC3	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.7734438360146196	[30]	[22,7,16,18]	-9	hSpCas9	negative selection	8605392
49194258	49194281	X	-	27260156	PC3	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.25036753454626215	[372]	[240,381,601,669]	5	hSpCas9	negative selection	8669645
49194323	49194346	X	-	27260156	PC3	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.2496124257130139	[741]	[495,999,1055,1125]	5	hSpCas9	negative selection	8669646
49193412	49193435	X	-	27260156	PC3	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.09717816821826841	[979]	[672,807,1499,908]	-2	hSpCas9	negative selection	8669647
49197728	49197751	X	+	27260156	PATU8988T	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.5152217426530962	[666]	[903,936,1049,781]	8	hSpCas9	negative selection	8726641
49197714	49197737	X	-	27260156	PATU8988T	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.21694586220144985	[701]	[757,915,729,759]	4	hSpCas9	negative selection	8726642
49193272	49193295	X	+	27260156	PATU8988T	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.4854764930517925	[30]	[18,36,1,29]	-7	hSpCas9	negative selection	8726643
49194258	49194281	X	-	27260156	PATU8988T	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	-0.3231250903109028	[372]	[334,356,153,316]	-5	hSpCas9	negative selection	8790896
49194323	49194346	X	-	27260156	PATU8988T	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.01438905890204667	[741]	[562,676,664,1010]	0	hSpCas9	negative selection	8790897
49193412	49193435	X	-	27260156	PATU8988T	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.07038632853546978	[979]	[803,730,1022,1042]	-1	hSpCas9	negative selection	8790898
49197728	49197751	X	+	27260156	T47D	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.4032751007717267	[666]	[1113,868,951,1195]	8	hSpCas9	negative selection	8847892
49197714	49197737	X	-	27260156	T47D	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.29087512094406764	[701]	[975,933,1031,1066]	6	hSpCas9	negative selection	8847893
49193272	49193295	X	+	27260156	T47D	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-1.3566073446295412	[30]	[9,21,4,18]	-9	hSpCas9	negative selection	8847894
49194258	49194281	X	-	27260156	T47D	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.4057340720764095	[372]	[526,676,440,652]	8	hSpCas9	negative selection	8912147
49194323	49194346	X	-	27260156	T47D	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.06978942283492617	[741]	[877,732,947,1089]	1	hSpCas9	negative selection	8912148
49193412	49193435	X	-	27260156	T47D	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.05437160769585181	[979]	[1190,1139,1156,898]	-1	hSpCas9	negative selection	8912149
49197728	49197751	X	+	27260156	SU8686	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.11720349179565748	[666]	[674,688,725,794]	2	hSpCas9	negative selection	8969143
49197714	49197737	X	-	27260156	SU8686	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.5364476891935737	[701]	[972,906,969,1232]	8	hSpCas9	negative selection	8969144
49193272	49193295	X	+	27260156	SU8686	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	0.29270419003667403	[30]	[12,17,26,108]	5	hSpCas9	negative selection	8969145
49194258	49194281	X	-	27260156	SU8686	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.3292594559190519	[372]	[408,396,447,644]	5	hSpCas9	negative selection	9033398
49194323	49194346	X	-	27260156	SU8686	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.13007379515877848	[741]	[544,738,979,1029]	2	hSpCas9	negative selection	9033399
49193412	49193435	X	-	27260156	SU8686	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.08080987671710882	[979]	[758,1073,917,913]	-1	hSpCas9	negative selection	9033400
49197728	49197751	X	+	27260156	SKES1	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.5044149482670915	[666]	[1262,1038,840,707]	8	hSpCas9	negative selection	9090394
49197714	49197737	X	-	27260156	SKES1	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.4244088716385641	[701]	[851,881,1112,886]	8	hSpCas9	negative selection	9090395
49193272	49193295	X	+	27260156	SKES1	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.5294332791077654	[30]	[23,35,18,9]	-8	hSpCas9	negative selection	9090396
49194258	49194281	X	-	27260156	SKES1	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.3593440560269039	[372]	[805,317,501,322]	7	hSpCas9	negative selection	9154649
49194323	49194346	X	-	27260156	SKES1	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.17227864843373586	[741]	[963,955,826,636]	4	hSpCas9	negative selection	9154650
49193412	49193435	X	-	27260156	SKES1	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.02331722217083443	[979]	[1137,996,931,816]	0	hSpCas9	negative selection	9154651
49197728	49197751	X	+	27260156	TOV112D	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.10524303995299322	[666]	[710,801,840,543]	2	hSpCas9	negative selection	9211645
49197714	49197737	X	-	27260156	TOV112D	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.13054508345705462	[701]	[579,965,729,831]	2	hSpCas9	negative selection	9211646
49193272	49193295	X	+	27260156	TOV112D	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.670715620275832	[30]	[20,5,35,11]	-8	hSpCas9	negative selection	9211647
49194258	49194281	X	-	27260156	TOV112D	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.4269746836300209	[372]	[451,739,497,375]	7	hSpCas9	negative selection	9275900
49194323	49194346	X	-	27260156	TOV112D	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.3291879563495915	[741]	[887,1074,870,929]	6	hSpCas9	negative selection	9275901
49193412	49193435	X	-	27260156	TOV112D	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.26290573873199496	[979]	[903,969,611,828]	-5	hSpCas9	negative selection	9275902
49197728	49197751	X	+	27260156	TC71	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.26258543965737613	[666]	[804,875,790,968]	6	hSpCas9	negative selection	9332896
49197714	49197737	X	-	27260156	TC71	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.19905953512698404	[701]	[787,996,836,833]	5	hSpCas9	negative selection	9332897
49193272	49193295	X	+	27260156	TC71	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	-0.8481403038320874	[30]	[36,4,28,0]	-9	hSpCas9	negative selection	9332898
49194258	49194281	X	-	27260156	TC71	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.021274715202091787	[372]	[381,409,374,460]	0	hSpCas9	negative selection	9397151
49194323	49194346	X	-	27260156	TC71	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.15323594749883085	[741]	[754,983,824,984]	4	hSpCas9	negative selection	9397152
49193412	49193435	X	-	27260156	TC71	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.2634784860386842	[979]	[822,852,940,882]	-6	hSpCas9	negative selection	9397153
49197728	49197751	X	+	27260156	TC32	viability	CGAACTCGACCTCGATGCTGAGG	SYP	ENSG00000102003	0.36514436940324524	[666]	[677,723,914,935]	6	hSpCas9	negative selection	9454147
49197714	49197737	X	-	27260156	TC32	viability	TCGAGTTCGAGTACCCCTTCAGG	SYP	ENSG00000102003	0.37930182838450865	[701]	[834,521,1105,1107]	6	hSpCas9	negative selection	9454148
49193272	49193295	X	+	27260156	TC32	viability	CACCGAGGTGTTGAGTCCCGAGG	SYP	ENSG00000102003	1.0517676322547036	[30]	[64,74,66,22]	9	hSpCas9	negative selection	9454149
49194258	49194281	X	-	27260156	TC32	viability	AGCCGAATTCTTTGTCACCGTGG	SYP	ENSG00000102003	0.2526786879951429	[372]	[509,135,650,490]	4	hSpCas9	negative selection	9518402
49194323	49194346	X	-	27260156	TC32	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.017731883947845195	[741]	[619,464,963,814]	0	hSpCas9	negative selection	9518403
49193412	49193435	X	-	27260156	TC32	viability	CATGTGGCTAGTTAGCTCATCGG	SYP	ENSG00000102003	-0.1056682192735755	[979]	[694,708,1207,899]	-2	hSpCas9	negative selection	9518404
49191483	49191506	X	-	27869803	HPAFII	viability after 27 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	1.014435546530112	[418]	[630,289,NaN]	8	hSpCas9	negative selection	9609035
49193400	49193423	X	-	27869803	HPAFII	viability after 27 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.12124980999043869	[223]	[90,158,NaN]	1	hSpCas9	negative selection	9609036
49194265	49194288	X	+	27869803	HPAFII	viability after 27 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.8466604589921359	[139]	[73,180,NaN]	7	hSpCas9	negative selection	9609037
49197622	49197645	X	+	27869803	HPAFII	viability after 27 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	0.5614856331543774	[792]	[551,667,NaN]	4	hSpCas9	negative selection	9609038
49191483	49191506	X	-	27869803	HPAFII	viability after 15 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	0.5838647900913355	[418]	[891,539,NaN]	6	hSpCas9	negative selection	9691484
49193400	49193423	X	-	27869803	HPAFII	viability after 15 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	-0.41369596596346125	[223]	[242,141,NaN]	-4	hSpCas9	negative selection	9691485
49194265	49194288	X	+	27869803	HPAFII	viability after 15 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.20387348521079773	[139]	[176,170,NaN]	2	hSpCas9	negative selection	9691486
49197622	49197645	X	+	27869803	HPAFII	viability after 15 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.26718581576173395	[792]	[812,642,NaN]	-3	hSpCas9	negative selection	9691487
49191483	49191506	X	-	27869803	ASPC1	viability after 36 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	-0.25399320666744063	[1127]	[290,269,401]	-3	hSpCas9	negative selection	9773933
49193400	49193423	X	-	27869803	ASPC1	viability after 36 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.3944712245086442	[662]	[105,394,367]	4	hSpCas9	negative selection	9773934
49194265	49194288	X	+	27869803	ASPC1	viability after 36 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.3688969712880495	[429]	[169,390,51]	3	hSpCas9	negative selection	9773935
49197622	49197645	X	+	27869803	ASPC1	viability after 36 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.47869862132516694	[1946]	[532,547,402]	-5	hSpCas9	negative selection	9773936
49191483	49191506	X	-	27869803	PATU8988S	viability after 35 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	0.0818477125988939	[858]	[434,296,NaN]	1	hSpCas9	negative selection	9856382
49193400	49193423	X	-	27869803	PATU8988S	viability after 35 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	-0.8067598093215875	[590]	[166,104,NaN]	-7	hSpCas9	negative selection	9856383
49194265	49194288	X	+	27869803	PATU8988S	viability after 35 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.3928399343850905	[340]	[101,258,NaN]	4	hSpCas9	negative selection	9856384
49197622	49197645	X	+	27869803	PATU8988S	viability after 35 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.3179712693345529	[1816]	[606,566,NaN]	-3	hSpCas9	negative selection	9856385
49191483	49191506	X	-	27869803	PATU8988S	viability after 31 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	0.10946753151775468	[858]	[376,359,NaN]	1	hSpCas9	negative selection	9938831
49193400	49193423	X	-	27869803	PATU8988S	viability after 31 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	-0.734860432269609	[590]	[145,135,NaN]	-7	hSpCas9	negative selection	9938832
49194265	49194288	X	+	27869803	PATU8988S	viability after 31 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	0.37305134905126724	[340]	[55,328,NaN]	4	hSpCas9	negative selection	9938833
49197622	49197645	X	+	27869803	PATU8988S	viability after 31 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	-0.26431889926307917	[1816]	[538,684,NaN]	-3	hSpCas9	negative selection	9938834
49191483	49191506	X	-	27869803	HPAFII	viability after 35 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	1.03649450001086	[418]	[404,468,NaN]	7	hSpCas9	negative selection	10021280
49193400	49193423	X	-	27869803	HPAFII	viability after 35 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	-0.09777634488531545	[223]	[41,177,NaN]	0	hSpCas9	negative selection	10021281
49194265	49194288	X	+	27869803	HPAFII	viability after 35 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	1.283274616178908	[139]	[116,234,NaN]	8	hSpCas9	negative selection	10021282
49197622	49197645	X	+	27869803	HPAFII	viability after 35 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	0.5135416482474093	[792]	[407,758,NaN]	3	hSpCas9	negative selection	10021283
49191483	49191506	X	-	27869803	HPAFII	viability after 31 days	CAGGGCGACTATGGGCAGCAAGG	SYP	ENSG00000102003	1.0256934427882256	[418]	[528,423,NaN]	7	hSpCas9	negative selection	10103729
49193400	49193423	X	-	27869803	HPAFII	viability after 31 days	TAGCTCATCGGCATGGGCCAAGG	SYP	ENSG00000102003	0.021016155639288298	[223]	[72,186,NaN]	0	hSpCas9	negative selection	10103730
49194265	49194288	X	+	27869803	HPAFII	viability after 31 days	GACAAAGAATTCGGCTGACGAGG	SYP	ENSG00000102003	1.188537087029894	[139]	[124,237,NaN]	8	hSpCas9	negative selection	10103731
49197622	49197645	X	+	27869803	HPAFII	viability after 31 days	TGGGCAGGAGCTACTTGCGGGGG	SYP	ENSG00000102003	0.3073730785926603	[792]	[443,666,NaN]	2	hSpCas9	negative selection	10103732
49193416	49193439	X	+	28162770	P31FUJ	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	-0.007242503999247529	[129]	[151]	0	hSpCas9	negative selection	10246236
49194241	49194264	X	+	28162770	P31FUJ	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.20036509897000412	[256]	[346]	2	hSpCas9	negative selection	10246237
49193431	49193454	X	+	28162770	P31FUJ	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	0.37126911925448214	[24]	[37]	4	hSpCas9	negative selection	10246238
49197810	49197833	X	+	28162770	P31FUJ	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	0.4590755002232896	[64]	[104]	5	hSpCas9	negative selection	10246239
49197796	49197819	X	-	28162770	P31FUJ	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.5728197504187701	[237]	[415]	6	hSpCas9	negative selection	10246240
49194323	49194346	X	-	28162770	P31FUJ	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.4836992871921121	[425]	[699]	5	hSpCas9	negative selection	10246241
49194292	49194315	X	+	28162770	P31FUJ	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.5118280518029006	[825]	[1383]	6	hSpCas9	negative selection	10246242
49193416	49193439	X	+	28162770	TF1	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	NaN	[NaN]	[347]	1	hSpCas9	negative selection	10415602
49194241	49194264	X	+	28162770	TF1	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	NaN	[NaN]	[473]	1	hSpCas9	negative selection	10415603
49193431	49193454	X	+	28162770	TF1	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	NaN	[NaN]	[78]	1	hSpCas9	negative selection	10415604
49197810	49197833	X	+	28162770	TF1	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	NaN	[NaN]	[88]	1	hSpCas9	negative selection	10415605
49197796	49197819	X	-	28162770	TF1	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	NaN	[NaN]	[256]	1	hSpCas9	negative selection	10415606
49194323	49194346	X	-	28162770	TF1	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	NaN	[NaN]	[546]	1	hSpCas9	negative selection	10415607
49194292	49194315	X	+	28162770	TF1	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	NaN	[NaN]	[672]	1	hSpCas9	negative selection	10415608
49193416	49193439	X	+	28162770	SKM1	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	0.21362221170871581	[39]	[81]	2	hSpCas9	negative selection	10584968
49194241	49194264	X	+	28162770	SKM1	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	-0.5064998722940763	[89]	[111]	-4	hSpCas9	negative selection	10584969
49193431	49193454	X	+	28162770	SKM1	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	-0.1781455082472807	[15]	[24]	-1	hSpCas9	negative selection	10584970
49197810	49197833	X	+	28162770	SKM1	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	-0.637577126884578	[21]	[24]	-5	hSpCas9	negative selection	10584971
49197796	49197819	X	-	28162770	SKM1	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.288422291671645	[43]	[94]	3	hSpCas9	negative selection	10584972
49194323	49194346	X	-	28162770	SKM1	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.21131837517802088	[106]	[218]	2	hSpCas9	negative selection	10584973
49194292	49194315	X	+	28162770	SKM1	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.08254114273009039	[163]	[306]	0	hSpCas9	negative selection	10584974
49193416	49193439	X	+	28162770	SKM1	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	0.21362221170871581	[39]	[81]	2	hSpCas9	negative selection	10754334
49194241	49194264	X	+	28162770	SKM1	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	-0.5064998722940763	[89]	[111]	-4	hSpCas9	negative selection	10754335
49193431	49193454	X	+	28162770	SKM1	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	-0.1781455082472807	[15]	[24]	-1	hSpCas9	negative selection	10754336
49197810	49197833	X	+	28162770	SKM1	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	-0.637577126884578	[21]	[24]	-5	hSpCas9	negative selection	10754337
49197796	49197819	X	-	28162770	SKM1	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.288422291671645	[43]	[94]	3	hSpCas9	negative selection	10754338
49194323	49194346	X	-	28162770	SKM1	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.21131837517802088	[106]	[218]	2	hSpCas9	negative selection	10754339
49194292	49194315	X	+	28162770	SKM1	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.08254114273009039	[163]	[306]	0	hSpCas9	negative selection	10754340
49193416	49193439	X	+	28162770	PL21	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	-1.0014942466803305	[137]	[29]	-6	hSpCas9	negative selection	10923700
49194241	49194264	X	+	28162770	PL21	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	-0.4597849439130582	[315]	[99]	-3	hSpCas9	negative selection	10923701
49193431	49193454	X	+	28162770	PL21	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	0.042598337502840256	[57]	[25]	0	hSpCas9	negative selection	10923702
49197810	49197833	X	+	28162770	PL21	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	-1.0014942466803305	[91]	[19]	-6	hSpCas9	negative selection	10923703
49197796	49197819	X	-	28162770	PL21	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	-0.1767146909016356	[173]	[66]	-1	hSpCas9	negative selection	10923704
49194323	49194346	X	-	28162770	PL21	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.2984191320698093	[382]	[204]	2	hSpCas9	negative selection	10923705
49194292	49194315	X	+	28162770	PL21	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.7709347832838824	[613]	[455]	6	hSpCas9	negative selection	10923706
49193416	49193439	X	+	28162770	P31FUJ	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	-0.007242503999247529	[129]	[151]	0	hSpCas9	negative selection	11093066
49194241	49194264	X	+	28162770	P31FUJ	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.20036509897000412	[256]	[346]	2	hSpCas9	negative selection	11093067
49193431	49193454	X	+	28162770	P31FUJ	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	0.37126911925448214	[24]	[37]	4	hSpCas9	negative selection	11093068
49197810	49197833	X	+	28162770	P31FUJ	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	0.4590755002232896	[64]	[104]	5	hSpCas9	negative selection	11093069
49197796	49197819	X	-	28162770	P31FUJ	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.5728197504187701	[237]	[415]	6	hSpCas9	negative selection	11093070
49194323	49194346	X	-	28162770	P31FUJ	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.4836992871921121	[425]	[699]	5	hSpCas9	negative selection	11093071
49194292	49194315	X	+	28162770	P31FUJ	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.5118280518029006	[825]	[1383]	6	hSpCas9	negative selection	11093072
49193416	49193439	X	+	28162770	OCIAML5	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	1.007902977357029	[99]	[362]	8	hSpCas9	negative selection	11262432
49194241	49194264	X	+	28162770	OCIAML5	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.572431257663913	[132]	[356]	5	hSpCas9	negative selection	11262433
49193431	49193454	X	+	28162770	OCIAML5	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	1.0913499007696355	[12]	[49]	8	hSpCas9	negative selection	11262434
49197810	49197833	X	+	28162770	OCIAML5	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	1.1057051937467055	[25]	[100]	8	hSpCas9	negative selection	11262435
49197796	49197819	X	-	28162770	OCIAML5	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.684600372816378	[80]	[234]	6	hSpCas9	negative selection	11262436
49194323	49194346	X	-	28162770	OCIAML5	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.7194284337786054	[286]	[852]	6	hSpCas9	negative selection	11262437
49194292	49194315	X	+	28162770	OCIAML5	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.4521427982024673	[425]	[1051]	4	hSpCas9	negative selection	11262438
49193416	49193439	X	+	28162770	EOL1	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	-0.0323835065375796	[164]	[84]	0	hSpCas9	negative selection	11431798
49194241	49194264	X	+	28162770	EOL1	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.27714756220031456	[483]	[308]	2	hSpCas9	negative selection	11431799
49193431	49193454	X	+	28162770	EOL1	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	1.2655846894056013	[59]	[75]	9	hSpCas9	negative selection	11431800
49197810	49197833	X	+	28162770	EOL1	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	0.887553564088333	[157]	[153]	7	hSpCas9	negative selection	11431801
49197796	49197819	X	-	28162770	EOL1	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.5452602972408926	[185]	[142]	5	hSpCas9	negative selection	11431802
49194323	49194346	X	-	28162770	EOL1	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.8657740621453681	[500]	[480]	7	hSpCas9	negative selection	11431803
49194292	49194315	X	+	28162770	EOL1	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.5223180485923111	[784]	[593]	5	hSpCas9	negative selection	11431804
49193416	49193439	X	+	28162770	MOLM13	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	-0.0593576213202901	[146]	[101]	0	hSpCas9	negative selection	11601164
49194241	49194264	X	+	28162770	MOLM13	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	1.3083526154141214	[319]	[572]	8	hSpCas9	negative selection	11601165
49193431	49193454	X	+	28162770	MOLM13	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	1.8890270803598403	[58]	[157]	9	hSpCas9	negative selection	11601166
49197810	49197833	X	+	28162770	MOLM13	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	-0.9967788854588655	[137]	[49]	-5	hSpCas9	negative selection	11601167
49197796	49197819	X	-	28162770	MOLM13	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.113356621225289	[178]	[139]	0	hSpCas9	negative selection	11601168
49194323	49194346	X	-	28162770	MOLM13	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.7100450577024568	[579]	[685]	5	hSpCas9	negative selection	11601169
49194292	49194315	X	+	28162770	MOLM13	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.2431190215769936	[1011]	[865]	1	hSpCas9	negative selection	11601170
49193416	49193439	X	+	28162770	HEL	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	0.3062133609000367	[148]	[117]	2	hSpCas9	negative selection	11770530
49194241	49194264	X	+	28162770	HEL	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.3814735190196189	[325]	[271]	3	hSpCas9	negative selection	11770531
49193431	49193454	X	+	28162770	HEL	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	1.670219568422464	[51]	[105]	9	hSpCas9	negative selection	11770532
49197810	49197833	X	+	28162770	HEL	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	0.05238307250898222	[133]	[88]	0	hSpCas9	negative selection	11770533
49197796	49197819	X	-	28162770	HEL	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.04007432954574189	[204]	[134]	0	hSpCas9	negative selection	11770534
49194323	49194346	X	-	28162770	HEL	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.5124824460490154	[416]	[380]	4	hSpCas9	negative selection	11770535
49194292	49194315	X	+	28162770	HEL	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.3755646958056391	[697]	[579]	3	hSpCas9	negative selection	11770536
49193416	49193439	X	+	28162770	MV411	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	0.26238789224874703	[95]	[96]	2	hSpCas9	negative selection	11939896
49194241	49194264	X	+	28162770	MV411	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.7864637673370725	[233]	[339]	7	hSpCas9	negative selection	11939897
49193431	49193454	X	+	28162770	MV411	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	-0.36024502643846423	[31]	[20]	-3	hSpCas9	negative selection	11939898
49197810	49197833	X	+	28162770	MV411	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	1.2739097621439663	[53]	[109]	9	hSpCas9	negative selection	11939899
49197796	49197819	X	-	28162770	MV411	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	1.0547924728403792	[179]	[314]	8	hSpCas9	negative selection	11939900
49194323	49194346	X	-	28162770	MV411	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.41692807095666606	[368]	[414]	4	hSpCas9	negative selection	11939901
49194292	49194315	X	+	28162770	MV411	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.6809883477129461	[541]	[731]	6	hSpCas9	negative selection	11939902
49193416	49193439	X	+	28162770	MONOMAC1	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	0.011910043211942889	[76]	[88]	0	hSpCas9	negative selection	12109262
49194241	49194264	X	+	28162770	MONOMAC1	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.5972144877238699	[157]	[273]	6	hSpCas9	negative selection	12109263
49193431	49193454	X	+	28162770	MONOMAC1	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	-1.4194292683960015	[34]	[14]	-8	hSpCas9	negative selection	12109264
49197810	49197833	X	+	28162770	MONOMAC1	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	0.29394950545258847	[36]	[51]	3	hSpCas9	negative selection	12109265
49197796	49197819	X	-	28162770	MONOMAC1	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.030032061486367556	[87]	[102]	0	hSpCas9	negative selection	12109266
49194323	49194346	X	-	28162770	MONOMAC1	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	-0.37945279268506305	[260]	[229]	-3	hSpCas9	negative selection	12109267
49194292	49194315	X	+	28162770	MONOMAC1	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	-0.1507077960040808	[428]	[442]	-1	hSpCas9	negative selection	12109268
49193416	49193439	X	+	28162770	OCIAML2	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	1.6858746604378296	[11]	[213]	9	hSpCas9	negative selection	12278628
49194241	49194264	X	+	28162770	OCIAML2	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.9353625344336756	[49]	[529]	8	hSpCas9	negative selection	12278629
49193431	49193454	X	+	28162770	OCIAML2	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	0.966775487065137	[5]	[64]	8	hSpCas9	negative selection	12278630
49197810	49197833	X	+	28162770	OCIAML2	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	0.747793693891341	[12]	[120]	7	hSpCas9	negative selection	12278631
49197796	49197819	X	-	28162770	OCIAML2	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.07369069098164915	[29]	[174]	0	hSpCas9	negative selection	12278632
49194323	49194346	X	-	28162770	OCIAML2	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.44026270092385367	[47]	[360]	4	hSpCas9	negative selection	12278633
49194292	49194315	X	+	28162770	OCIAML2	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.3292110431581363	[109]	[765]	3	hSpCas9	negative selection	12278634
49193416	49193439	X	+	28162770	OCIAML3	viability	TGAGCTAACTAGCCACATGAAGG	SYP	ENSG00000102003	0.20507966574984027	[24]	[86]	2	hSpCas9	negative selection	12447994
49194241	49194264	X	+	28162770	OCIAML3	viability	GAGGAAGGCAAACACGGCCACGG	SYP	ENSG00000102003	0.8502944534598755	[60]	[331]	7	hSpCas9	negative selection	12447995
49193431	49193454	X	+	28162770	OCIAML3	viability	CATGAAGGCGAACACAGCCGTGG	SYP	ENSG00000102003	0.03826057517534931	[9]	[30]	0	hSpCas9	negative selection	12447996
49197810	49197833	X	+	28162770	OCIAML3	viability	GCATGTGGCAAAGGCGAAGATGG	SYP	ENSG00000102003	0.10643207781692893	[39]	[129]	1	hSpCas9	negative selection	12447997
49197796	49197819	X	-	28162770	OCIAML3	viability	GCCACATGCGGCAGCTACAGTGG	SYP	ENSG00000102003	0.33887816381729985	[43]	[167]	3	hSpCas9	negative selection	12447998
49194323	49194346	X	-	28162770	OCIAML3	viability	TTTGATGCACCCACCTGCCGAGG	SYP	ENSG00000102003	0.40929750439950885	[108]	[436]	4	hSpCas9	negative selection	12447999
49194292	49194315	X	+	28162770	OCIAML3	viability	GTCCCCAACTAAGAAGACCTTGG	SYP	ENSG00000102003	0.12470624928582041	[174]	[575]	1	hSpCas9	negative selection	12448000