Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10716
• Symbol:TBR1
• Description:T-box brain transcription factor 1

DataSource: http://genomecrispr.dkfz.de/#!/results/TBR1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
161416760	161416783	2	-	26472758	Jiyoye	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	0.32725183720892415	[166]	[157]	2	hSpCas9	negative selection	162559
161416747	161416770	2	-	26472758	Jiyoye	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	0.2944074513439236	[132]	[122]	2	hSpCas9	negative selection	162560
161416814	161416837	2	-	26472758	Jiyoye	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	-1.3243357825682247	[175]	[52]	-7	hSpCas9	negative selection	162561
161416887	161416910	2	-	26472758	Jiyoye	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	0.018610093588220633	[71]	[54]	0	hSpCas9	negative selection	162562
161417004	161417027	2	+	26472758	Jiyoye	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.3076397079549591	[224]	[209]	2	hSpCas9	negative selection	162563
161417081	161417104	2	+	26472758	Jiyoye	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	0.11766876431088855	[98]	[80]	0	hSpCas9	negative selection	162564
161417756	161417779	2	+	26472758	Jiyoye	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	-1.5020591545709445	[153]	[40]	-7	hSpCas9	negative selection	162565
161418921	161418944	2	+	26472758	Jiyoye	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	-1.8953873885145578	[73]	[14]	-8	hSpCas9	negative selection	162566
161418942	161418965	2	+	26472758	Jiyoye	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	-0.21431299524039682	[99]	[64]	-1	hSpCas9	negative selection	162567
161416617	161416640	2	+	26472758	Jiyoye	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	-1.463189338077531	[116]	[31]	-7	hSpCas9	negative selection	162568
161416760	161416783	2	-	26472758	KBM7	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-0.05069556588573121	[832,582]	[266,361]	0	hSpCas9	negative selection	353677
161416747	161416770	2	-	26472758	KBM7	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	-0.48729708818901557	[440,536]	[119,207]	-4	hSpCas9	negative selection	353678
161416814	161416837	2	-	26472758	KBM7	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	0.32547379850763924	[192,136]	[95,95]	3	hSpCas9	negative selection	353679
161416887	161416910	2	-	26472758	KBM7	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	0.3476017714871352	[252,143]	[30,191]	3	hSpCas9	negative selection	353680
161417004	161417027	2	+	26472758	KBM7	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.2765188325609187	[781,656]	[452,367]	3	hSpCas9	negative selection	353681
161417081	161417104	2	+	26472758	KBM7	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	0.7426267328101981	[498,494]	[491,303]	7	hSpCas9	negative selection	353682
161417756	161417779	2	+	26472758	KBM7	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	-0.11074395755503574	[212,167]	[103,62]	-1	hSpCas9	negative selection	353683
161418921	161418944	2	+	26472758	KBM7	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	-0.17108813110165277	[129,60]	[64,14]	-2	hSpCas9	negative selection	353684
161418942	161418965	2	+	26472758	KBM7	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	0.3518247993961303	[239,295]	[147,176]	4	hSpCas9	negative selection	353685
161416617	161416640	2	+	26472758	KBM7	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	0.35296552187217484	[351,422]	[282,193]	4	hSpCas9	negative selection	353686
161416760	161416783	2	-	26472758	Raji	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	0.1519299743268614	[286]	[73]	1	hSpCas9	negative selection	544795
161416747	161416770	2	-	26472758	Raji	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	-0.20887580942707082	[253]	[50]	-2	hSpCas9	negative selection	544796
161416814	161416837	2	-	26472758	Raji	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	-0.9894780038789894	[76]	[8]	-6	hSpCas9	negative selection	544797
161416887	161416910	2	-	26472758	Raji	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	2.4228853611015286	[44]	[55]	9	hSpCas9	negative selection	544798
161417004	161417027	2	+	26472758	Raji	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.3465711992530255	[243]	[71]	3	hSpCas9	negative selection	544799
161417081	161417104	2	+	26472758	Raji	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	0.34995383864767776	[212]	[62]	3	hSpCas9	negative selection	544800
161417756	161417779	2	+	26472758	Raji	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	-0.46198211029653813	[183]	[30]	-4	hSpCas9	negative selection	544801
161418921	161418944	2	+	26472758	Raji	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	-1.3520480832636979	[76]	[6]	-7	hSpCas9	negative selection	544802
161418942	161418965	2	+	26472758	Raji	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	-0.36654765295881286	[199]	[35]	-3	hSpCas9	negative selection	544803
161416617	161416640	2	+	26472758	Raji	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	0.21608979481609938	[229]	[61]	2	hSpCas9	negative selection	544804
161416760	161416783	2	-	26472758	K562	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-1.4464124081615322	[635]	[196]	-6	hSpCas9	negative selection	735913
161416747	161416770	2	-	26472758	K562	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	0.2074245201842453	[394]	[384]	1	hSpCas9	negative selection	735914
161416814	161416837	2	-	26472758	K562	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	0.3368649764310421	[135]	[144]	2	hSpCas9	negative selection	735915
161416887	161416910	2	-	26472758	K562	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	-0.7772763434328721	[267]	[131]	-4	hSpCas9	negative selection	735916
161417004	161417027	2	+	26472758	K562	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	-0.0734682019990518	[712]	[571]	0	hSpCas9	negative selection	735917
161417081	161417104	2	+	26472758	K562	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	-0.4959374557005334	[425]	[254]	-3	hSpCas9	negative selection	735918
161417756	161417779	2	+	26472758	K562	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	-0.6604240392932128	[175]	[93]	-4	hSpCas9	negative selection	735919
161418921	161418944	2	+	26472758	K562	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	0.4525269229966473	[57]	[66]	3	hSpCas9	negative selection	735920
161418942	161418965	2	+	26472758	K562	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	0.5197314632786776	[194]	[235]	4	hSpCas9	negative selection	735921
161416617	161416640	2	+	26472758	K562	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	-0.6553538245948989	[277]	[148]	-4	hSpCas9	negative selection	735922
161416527	161416550	2	+	26627737	DLD1	viability	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	-0.2262284864891429	[430]	[86,133,123]	-2	hSpCas9	negative selection	809007
161417044	161417067	2	-	26627737	DLD1	viability	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	1.1195707659536118	[595]	[377,428,407]	8	hSpCas9	negative selection	809008
161417793	161417816	2	+	26627737	DLD1	viability	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.0170426152940113	[906]	[204,299,346]	0	hSpCas9	negative selection	809009
161417800	161417823	2	-	26627737	DLD1	viability	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	-0.41067223435817846	[746]	[96,323,120]	-4	hSpCas9	negative selection	809010
161418984	161419007	2	-	26627737	DLD1	viability	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	-0.1299506955497981	[712]	[262,203,151]	-1	hSpCas9	negative selection	809011
161423826	161423849	2	-	26627737	DLD1	viability	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	0.08388582101179953	[309]	[100,114,93]	0	hSpCas9	negative selection	809012
161416527	161416550	2	+	26627737	GBM cells	viability after 5 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	-0.6744139253520672	[246]	[82,82]	-8	hSpCas9	negative selection	891322
161417044	161417067	2	-	26627737	GBM cells	viability after 5 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.4620672281605054	[510]	[331,422]	7	hSpCas9	negative selection	891323
161417793	161417816	2	+	26627737	GBM cells	viability after 5 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	-0.10108612511431453	[336]	[180,155]	-1	hSpCas9	negative selection	891324
161417800	161417823	2	-	26627737	GBM cells	viability after 5 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.12644959949809323	[239]	[143,136]	2	hSpCas9	negative selection	891325
161418984	161419007	2	-	26627737	GBM cells	viability after 5 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	-0.11611433434664598	[385]	[185,195]	-2	hSpCas9	negative selection	891326
161423826	161423849	2	-	26627737	GBM cells	viability after 5 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.41041418322204326	[170]	[55,81]	-6	hSpCas9	negative selection	891327
161416527	161416550	2	+	26627737	GBM cells	viability after 13 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	-0.27874560160279516	[246]	[158,70]	-3	hSpCas9	negative selection	973637
161417044	161417067	2	-	26627737	GBM cells	viability after 13 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.7275050797841465	[510]	[468,450]	8	hSpCas9	negative selection	973638
161417793	161417816	2	+	26627737	GBM cells	viability after 13 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	-0.09441759541893047	[336]	[221,129]	-1	hSpCas9	negative selection	973639
161417800	161417823	2	-	26627737	GBM cells	viability after 13 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.7786789096149376	[239]	[261,191]	8	hSpCas9	negative selection	973640
161418984	161419007	2	-	26627737	GBM cells	viability after 13 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	-0.053140563186186984	[385]	[272,143]	0	hSpCas9	negative selection	973641
161423826	161423849	2	-	26627737	GBM cells	viability after 13 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.28517229944991573	[170]	[79,72]	-3	hSpCas9	negative selection	973642
161416527	161416550	2	+	26627737	GBM cells	viability after 21 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	-0.691164473523695	[246]	[103,63]	-6	hSpCas9	negative selection	1055952
161417044	161417067	2	-	26627737	GBM cells	viability after 21 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.5890317203605591	[510]	[426,408]	6	hSpCas9	negative selection	1055953
161417793	161417816	2	+	26627737	GBM cells	viability after 21 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.10681907226583531	[336]	[216,178]	1	hSpCas9	negative selection	1055954
161417800	161417823	2	-	26627737	GBM cells	viability after 21 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.2888445297350694	[239]	[175,143]	3	hSpCas9	negative selection	1055955
161418984	161419007	2	-	26627737	GBM cells	viability after 21 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.3014246163228461	[385]	[259,256]	3	hSpCas9	negative selection	1055956
161423826	161423849	2	-	26627737	GBM cells	viability after 21 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.12540223505377446	[170]	[92,77]	-1	hSpCas9	negative selection	1055957
161416527	161416550	2	+	26627737	RPE1	viability after 9 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	-0.650690535325818	[1140]	[120,364]	-5	hSpCas9	negative selection	1138267
161417044	161417067	2	-	26627737	RPE1	viability after 9 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.4578372034844962	[2244]	[760,1228]	3	hSpCas9	negative selection	1138268
161417793	161417816	2	+	26627737	RPE1	viability after 9 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.38732114351819547	[1159]	[257,754]	2	hSpCas9	negative selection	1138269
161417800	161417823	2	-	26627737	RPE1	viability after 9 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.9838878971517763	[817]	[409,630]	6	hSpCas9	negative selection	1138270
161418984	161419007	2	-	26627737	RPE1	viability after 9 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	-0.039275839548651326	[1492]	[322,624]	0	hSpCas9	negative selection	1138271
161423826	161423849	2	-	26627737	RPE1	viability after 9 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	3.405948386539154	[45]	[132,177]	9	hSpCas9	negative selection	1138272
161416527	161416550	2	+	26627737	RPE1	viability after 12 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	-0.7844698244740897	[1140]	[193,160]	-5	hSpCas9	negative selection	1220582
161417044	161417067	2	-	26627737	RPE1	viability after 12 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.8249635859192892	[2244]	[931,1212]	5	hSpCas9	negative selection	1220583
161417793	161417816	2	+	26627737	RPE1	viability after 12 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.36674123691529903	[1159]	[226,586]	2	hSpCas9	negative selection	1220584
161417800	161417823	2	-	26627737	RPE1	viability after 12 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	1.048970898309706	[817]	[393,518]	6	hSpCas9	negative selection	1220585
161418984	161419007	2	-	26627737	RPE1	viability after 12 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.05888029965169983	[1492]	[343,495]	0	hSpCas9	negative selection	1220586
161423826	161423849	2	-	26627737	RPE1	viability after 12 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	2.924065473244139	[45]	[86,100]	9	hSpCas9	negative selection	1220587
161416527	161416550	2	+	26627737	RPE1	viability after 15 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	-1.0357480353498643	[1140]	[104,207]	-6	hSpCas9	negative selection	1302897
161417044	161417067	2	-	26627737	RPE1	viability after 15 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.4032964759017934	[2244]	[761,914]	2	hSpCas9	negative selection	1302898
161417793	161417816	2	+	26627737	RPE1	viability after 15 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.5683907049428558	[1159]	[312,653]	3	hSpCas9	negative selection	1302899
161417800	161417823	2	-	26627737	RPE1	viability after 15 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	1.6703690098785386	[817]	[622,845]	8	hSpCas9	negative selection	1302900
161418984	161419007	2	-	26627737	RPE1	viability after 15 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	-0.515246301866586	[1492]	[154,430]	-3	hSpCas9	negative selection	1302901
161423826	161423849	2	-	26627737	RPE1	viability after 15 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	3.0949239542476956	[45]	[72,147]	9	hSpCas9	negative selection	1302902
161416527	161416550	2	+	26627737	RPE1	viability after 18 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	-0.025860835387983783	[1140]	[300,303]	0	hSpCas9	negative selection	1385212
161417044	161417067	2	-	26627737	RPE1	viability after 18 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.3041909577345694	[2244]	[647,854]	2	hSpCas9	negative selection	1385213
161417793	161417816	2	+	26627737	RPE1	viability after 18 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.6722851675264783	[1159]	[363,642]	4	hSpCas9	negative selection	1385214
161417800	161417823	2	-	26627737	RPE1	viability after 18 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	1.5913329721556353	[817]	[422,923]	8	hSpCas9	negative selection	1385215
161418984	161419007	2	-	26627737	RPE1	viability after 18 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	-0.7788319417797709	[1492]	[229,239]	-5	hSpCas9	negative selection	1385216
161423826	161423849	2	-	26627737	RPE1	viability after 18 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	3.574727852143117	[45]	[159,134]	9	hSpCas9	negative selection	1385217
161416527	161416550	2	+	26627737	HeLa	viability after 8 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.5468987985206074	[235]	[111,183,145]	5	hSpCas9	negative selection	1467527
161417044	161417067	2	-	26627737	HeLa	viability after 8 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	-0.06502694414331645	[1245]	[450,673,421]	0	hSpCas9	negative selection	1467528
161417793	161417816	2	+	26627737	HeLa	viability after 8 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.3110905610755185	[467]	[245,309,203]	3	hSpCas9	negative selection	1467529
161417800	161417823	2	-	26627737	HeLa	viability after 8 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.4174248912096575	[475]	[208,299,303]	4	hSpCas9	negative selection	1467530
161418984	161419007	2	-	26627737	HeLa	viability after 8 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.2129772390137431	[552]	[259,314,258]	2	hSpCas9	negative selection	1467531
161423826	161423849	2	-	26627737	HeLa	viability after 8 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.23586617398658202	[379]	[114,209,93]	-2	hSpCas9	negative selection	1467532
161416527	161416550	2	+	26627737	HeLa	viability after 12 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	1.19959635428121	[235]	[290,166,221]	8	hSpCas9	negative selection	1549842
161417044	161417067	2	-	26627737	HeLa	viability after 12 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.19858870203574197	[1245]	[706,393,695]	1	hSpCas9	negative selection	1549843
161417793	161417816	2	+	26627737	HeLa	viability after 12 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.6606911283051575	[467]	[321,236,365]	5	hSpCas9	negative selection	1549844
161417800	161417823	2	-	26627737	HeLa	viability after 12 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.21154570501644593	[475]	[244,197,243]	2	hSpCas9	negative selection	1549845
161418984	161419007	2	-	26627737	HeLa	viability after 12 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.571685678063133	[552]	[296,308,414]	5	hSpCas9	negative selection	1549846
161423826	161423849	2	-	26627737	HeLa	viability after 12 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.6140857153127179	[379]	[138,72,99]	-5	hSpCas9	negative selection	1549847
161416527	161416550	2	+	26627737	HeLa	viability after 15 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.5170419223566648	[235]	[54,166,195]	4	hSpCas9	negative selection	1632157
161417044	161417067	2	-	26627737	HeLa	viability after 15 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	-0.31049039617541285	[1245]	[492,311,421]	-3	hSpCas9	negative selection	1632158
161417793	161417816	2	+	26627737	HeLa	viability after 15 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.4681471712518113	[467]	[333,128,331]	4	hSpCas9	negative selection	1632159
161417800	161417823	2	-	26627737	HeLa	viability after 15 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.4167469017977847	[475]	[247,162,373]	3	hSpCas9	negative selection	1632160
161418984	161419007	2	-	26627737	HeLa	viability after 15 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.9416859128512198	[552]	[568,287,438]	7	hSpCas9	negative selection	1632161
161423826	161423849	2	-	26627737	HeLa	viability after 15 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.6686226372311964	[379]	[106,145,33]	-5	hSpCas9	negative selection	1632162
161416527	161416550	2	+	26627737	HeLa	viability after 18 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.5087784337631336	[235]	[33,139,195]	4	hSpCas9	negative selection	1714472
161417044	161417067	2	-	26627737	HeLa	viability after 18 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	-0.2716026140700414	[1245]	[339,273,421]	-2	hSpCas9	negative selection	1714473
161417793	161417816	2	+	26627737	HeLa	viability after 18 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.4906097755613957	[467]	[227,111,331]	4	hSpCas9	negative selection	1714474
161417800	161417823	2	-	26627737	HeLa	viability after 18 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.4202563027270419	[475]	[161,141,373]	3	hSpCas9	negative selection	1714475
161418984	161419007	2	-	26627737	HeLa	viability after 18 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.9386679213148228	[552]	[377,240,438]	7	hSpCas9	negative selection	1714476
161423826	161423849	2	-	26627737	HeLa	viability after 18 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.6407489704687395	[379]	[72,123,33]	-5	hSpCas9	negative selection	1714477
161416527	161416550	2	+	26627737	HCT116	viability after 6 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	3.4424994281996506	[231]	[255,473]	9	hSpCas9	negative selection	1796787
161417044	161417067	2	-	26627737	HCT116	viability after 6 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.6398745673972421	[1568]	[335,410]	3	hSpCas9	negative selection	1796788
161417793	161417816	2	+	26627737	HCT116	viability after 6 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.9121944416156179	[619]	[156,197]	5	hSpCas9	negative selection	1796789
161417800	161417823	2	-	26627737	HCT116	viability after 6 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	-0.13439931775696629	[485]	[164,16]	0	hSpCas9	negative selection	1796790
161418984	161419007	2	-	26627737	HCT116	viability after 6 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	1.692044850502894	[562]	[673,71]	8	hSpCas9	negative selection	1796791
161423826	161423849	2	-	26627737	HCT116	viability after 6 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.05938798794728439	[490]	[17,104]	0	hSpCas9	negative selection	1796792
161416527	161416550	2	+	26627737	HCT116	viability after 8 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.16021039520666228	[279]	[186,117,211]	1	hSpCas9	negative selection	1879102
161417044	161417067	2	-	26627737	HCT116	viability after 8 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.510172428674286	[505]	[484,403,304]	5	hSpCas9	negative selection	1879103
161417793	161417816	2	+	26627737	HCT116	viability after 8 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.8369459481252031	[291]	[284,356,220]	7	hSpCas9	negative selection	1879104
161417800	161417823	2	-	26627737	HCT116	viability after 8 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.8896960226153909	[232]	[273,261,178]	7	hSpCas9	negative selection	1879105
161418984	161419007	2	-	26627737	HCT116	viability after 8 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.09535093660566596	[464]	[286,306,227]	1	hSpCas9	negative selection	1879106
161423826	161423849	2	-	26627737	HCT116	viability after 8 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.3266618594701526	[244]	[72,114,133]	-4	hSpCas9	negative selection	1879107
161416527	161416550	2	+	26627737	HCT116	viability after 9 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.8488991980095156	[231]	[148,81]	6	hSpCas9	negative selection	1961417
161417044	161417067	2	-	26627737	HCT116	viability after 9 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	-0.10604485901274452	[1568]	[381,394]	0	hSpCas9	negative selection	1961418
161417793	161417816	2	+	26627737	HCT116	viability after 9 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.48589370182302194	[619]	[280,192]	3	hSpCas9	negative selection	1961419
161417800	161417823	2	-	26627737	HCT116	viability after 9 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	1.1235490298680246	[485]	[432,163]	7	hSpCas9	negative selection	1961420
161418984	161419007	2	-	26627737	HCT116	viability after 9 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	1.3264538876011291	[562]	[271,459]	8	hSpCas9	negative selection	1961421
161423826	161423849	2	-	26627737	HCT116	viability after 9 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-1.1898907061319168	[490]	[52,60]	-7	hSpCas9	negative selection	1961422
161416527	161416550	2	+	26627737	HCT116	viability after 12 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.5668984987166836	[279]	[191,126,334]	5	hSpCas9	negative selection	2043732
161417044	161417067	2	-	26627737	HCT116	viability after 12 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.47715451710847845	[505]	[369,432,308]	4	hSpCas9	negative selection	2043733
161417793	161417816	2	+	26627737	HCT116	viability after 12 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	1.0607956516727932	[291]	[230,353,383]	8	hSpCas9	negative selection	2043734
161417800	161417823	2	-	26627737	HCT116	viability after 12 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	1.1109209109244989	[232]	[354,245,183]	8	hSpCas9	negative selection	2043735
161418984	161419007	2	-	26627737	HCT116	viability after 12 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.3694360400247001	[464]	[162,460,339]	3	hSpCas9	negative selection	2043736
161423826	161423849	2	-	26627737	HCT116	viability after 12 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.08748292048961426	[244]	[86,98,179]	-1	hSpCas9	negative selection	2043737
161416527	161416550	2	+	26627737	HCT116	viability after 15 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.31338817948316755	[279]	[274,166,166]	3	hSpCas9	negative selection	2126047
161417044	161417067	2	-	26627737	HCT116	viability after 15 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.6602039714515714	[505]	[580,476,335]	6	hSpCas9	negative selection	2126048
161417793	161417816	2	+	26627737	HCT116	viability after 15 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.9366904890529903	[291]	[334,335,293]	7	hSpCas9	negative selection	2126049
161417800	161417823	2	-	26627737	HCT116	viability after 15 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.6156808629628829	[232]	[224,225,166]	5	hSpCas9	negative selection	2126050
161418984	161419007	2	-	26627737	HCT116	viability after 15 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.0911549373265017	[464]	[288,201,361]	0	hSpCas9	negative selection	2126051
161423826	161423849	2	-	26627737	HCT116	viability after 15 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	0.007084176713604395	[244]	[120,100,198]	0	hSpCas9	negative selection	2126052
161416527	161416550	2	+	26627737	HCT116	viability after 18 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.9125383394083026	[279]	[231,224,311]	7	hSpCas9	negative selection	2208362
161417044	161417067	2	-	26627737	HCT116	viability after 18 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.40676388187474444	[505]	[418,258,297]	3	hSpCas9	negative selection	2208363
161417793	161417816	2	+	26627737	HCT116	viability after 18 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	1.0555139009259007	[291]	[260,205,424]	7	hSpCas9	negative selection	2208364
161417800	161417823	2	-	26627737	HCT116	viability after 18 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.6049933830571882	[232]	[166,172,173]	5	hSpCas9	negative selection	2208365
161418984	161419007	2	-	26627737	HCT116	viability after 18 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.22927403103930533	[464]	[198,157,448]	2	hSpCas9	negative selection	2208366
161423826	161423849	2	-	26627737	HCT116	viability after 18 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.35718944862471647	[244]	[88,45,147]	-3	hSpCas9	negative selection	2208367
161416428	161416451	2	-	24336569	HL60	viability	AGAGCATGATAGAAGGAGAAAGG	TBR1	ENSG00000136535	-0.35837068104424774	[626]	[1034]	-3	hSpCas9	negative selection	2299181
161416435	161416458	2	-	24336569	HL60	viability	TTCTTGGAGAGCATGATAGAAGG	TBR1	ENSG00000136535	0.30721881907494325	[510]	[1337]	3	hSpCas9	negative selection	2299182
161416451	161416474	2	-	24336569	HL60	viability	GCTCACATTGAGAAATTTCTTGG	TBR1	ENSG00000136535	3.9629300187295566	[0]	[32]	9	hSpCas9	negative selection	2299183
161416471	161416494	2	+	24336569	HL60	viability	AGCAGCAGCTACCCACATTCAGG	TBR1	ENSG00000136535	0.5514268673414353	[522]	[1621]	5	hSpCas9	negative selection	2299184
161416482	161416505	2	-	24336569	HL60	viability	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	1.7693924600652942	[111]	[807]	9	hSpCas9	negative selection	2299185
161416499	161416522	2	-	24336569	HL60	viability	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	-0.7290822091998201	[899]	[1148]	-6	hSpCas9	negative selection	2299186
161416522	161416545	2	-	24336569	HL60	viability	TTGTCAGTGGTCGAGATAATGGG	TBR1	ENSG00000136535	1.0923029671078102	[249]	[1127]	8	hSpCas9	negative selection	2299187
161416527	161416550	2	+	24336569	HL60	viability	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	-0.3403528282051369	[833]	[1393]	-3	hSpCas9	negative selection	2299188
161416535	161416558	2	-	24336569	HL60	viability	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	-0.3673494455907276	[419]	[688]	-3	hSpCas9	negative selection	2299189
161416545	161416568	2	-	24336569	HL60	viability	TCAAAGGTGAACTTCTCTCCAGG	TBR1	ENSG00000136535	-0.0012937519449129908	[209]	[443]	0	hSpCas9	negative selection	2299190
161416428	161416451	2	-	24336569	KBM7	viability	AGAGCATGATAGAAGGAGAAAGG	TBR1	ENSG00000136535	0.43357383764602775	[508]	[1874]	4	hSpCas9	negative selection	2366358
161416435	161416458	2	-	24336569	KBM7	viability	TTCTTGGAGAGCATGATAGAAGG	TBR1	ENSG00000136535	0.3796304683144158	[566]	[2011]	3	hSpCas9	negative selection	2366359
161416451	161416474	2	-	24336569	KBM7	viability	GCTCACATTGAGAAATTTCTTGG	TBR1	ENSG00000136535	-4.9070108151861795	[10]	[0]	-9	hSpCas9	negative selection	2366360
161416471	161416494	2	+	24336569	KBM7	viability	AGCAGCAGCTACCCACATTCAGG	TBR1	ENSG00000136535	0.12185838066669863	[653]	[1940]	1	hSpCas9	negative selection	2366361
161416482	161416505	2	-	24336569	KBM7	viability	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	-0.03315107216437374	[295]	[788]	0	hSpCas9	negative selection	2366362
161416499	161416522	2	-	24336569	KBM7	viability	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	-0.1407301296169874	[980]	[2426]	-1	hSpCas9	negative selection	2366363
161416522	161416545	2	-	24336569	KBM7	viability	TTGTCAGTGGTCGAGATAATGGG	TBR1	ENSG00000136535	-0.006466269935278102	[280]	[762]	0	hSpCas9	negative selection	2366364
161416527	161416550	2	+	24336569	KBM7	viability	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.17034179155754925	[576]	[1770]	1	hSpCas9	negative selection	2366365
161416535	161416558	2	-	24336569	KBM7	viability	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	-0.20569059958663727	[251]	[595]	-2	hSpCas9	negative selection	2366366
161416545	161416568	2	-	24336569	KBM7	viability	TCAAAGGTGAACTTCTCTCCAGG	TBR1	ENSG00000136535	0.9246221048197034	[140]	[729]	7	hSpCas9	negative selection	2366367
161417011	161417034	2	-	27260157	DLD1	viability	AGGTACACCTGTGCTTTGCCGGG	TBR1	ENSG00000136535	0.571303430088276	[]	[]	8	hSpCas9	negative selection	2575376
161416771	161416794	2	+	27260157	DLD1	viability	AGTGCCATGTTCCCGTACCCCGG	TBR1	ENSG00000136535	0.240065427740321	[]	[]	4	hSpCas9	negative selection	2576385
161416833	161416856	2	-	27260157	DLD1	viability	GGTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.266987784787367	[]	[]	4	hSpCas9	negative selection	2581309
161416684	161416707	2	+	27260157	DLD1	viability	GAGCTTCGTCACAGTTTCGATGG	TBR1	ENSG00000136535	0.159851132050097	[]	[]	3	hSpCas9	negative selection	2582152
161416451	161416474	2	-	27260157	DLD1	viability	GCTCACATTGAGAAATTTCTTGG	TBR1	ENSG00000136535	0.955510701469078	[]	[]	9	hSpCas9	negative selection	2583246
161416823	161416846	2	-	27260157	DLD1	viability	GTAGCGGCTAGGGCTGCCGATGG	TBR1	ENSG00000136535	0.507645644303439	[]	[]	8	hSpCas9	negative selection	2585748
161416545	161416568	2	-	27260157	DLD1	viability	TCAAAGGTGAACTTCTCTCCAGG	TBR1	ENSG00000136535	-0.277868900651076	[]	[]	-2	hSpCas9	negative selection	2604948
161416471	161416494	2	+	27260157	DLD1	viability	AGCAGCAGCTACCCACATTCAGG	TBR1	ENSG00000136535	-0.033226946792523	[]	[]	0	hSpCas9	negative selection	2605360
161416435	161416458	2	-	27260157	DLD1	viability	TTCTTGGAGAGCATGATAGAAGG	TBR1	ENSG00000136535	-0.281445140091914	[]	[]	-2	hSpCas9	negative selection	2606820
161416499	161416522	2	-	27260157	DLD1	viability	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	0.74640204484313	[]	[]	8	hSpCas9	negative selection	2607312
161416482	161416505	2	-	27260157	DLD1	viability	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	0.585855643020212	[]	[]	8	hSpCas9	negative selection	2608168
161416850	161416873	2	-	27260157	DLD1	viability	GTTGGTGATGACCGGGTGGTGGG	TBR1	ENSG00000136535	-0.93492358163381	[]	[]	-6	hSpCas9	negative selection	2613066
161416522	161416545	2	-	27260157	DLD1	viability	TTGTCAGTGGTCGAGATAATGGG	TBR1	ENSG00000136535	0.0787942613938514	[]	[]	3	hSpCas9	negative selection	2613731
161416523	161416546	2	-	27260157	DLD1	viability	GTTGTCAGTGGTCGAGATAATGG	TBR1	ENSG00000136535	-1.54244702816265	[]	[]	-8	hSpCas9	negative selection	2614253
161416527	161416550	2	+	27260157	DLD1	viability	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.0254929667404419	[]	[]	0	hSpCas9	negative selection	2617061
161416535	161416558	2	-	27260157	DLD1	viability	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	0.0142553919881607	[]	[]	0	hSpCas9	negative selection	2623399
161416428	161416451	2	-	27260157	DLD1	viability	AGAGCATGATAGAAGGAGAAAGG	TBR1	ENSG00000136535	-0.487786163910522	[]	[]	-4	hSpCas9	negative selection	2644526
161417044	161417067	2	-	27260157	DLD1	viability	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.306935300788858	[]	[]	4	hSpCas9	negative selection	2647954
161417011	161417034	2	-	27260157	HT1080	viability	AGGTACACCTGTGCTTTGCCGGG	TBR1	ENSG00000136535	0.599909051622436	[]	[]	5	hSpCas9	negative selection	2651506
161416771	161416794	2	+	27260157	HT1080	viability	AGTGCCATGTTCCCGTACCCCGG	TBR1	ENSG00000136535	0.31187173807938	[]	[]	3	hSpCas9	negative selection	2652515
161416833	161416856	2	-	27260157	HT1080	viability	GGTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	-0.26831693114033	[]	[]	0	hSpCas9	negative selection	2657439
161416684	161416707	2	+	27260157	HT1080	viability	GAGCTTCGTCACAGTTTCGATGG	TBR1	ENSG00000136535	-0.972479446801065	[]	[]	-8	hSpCas9	negative selection	2658282
161416451	161416474	2	-	27260157	HT1080	viability	GCTCACATTGAGAAATTTCTTGG	TBR1	ENSG00000136535	0.227400150093963	[]	[]	2	hSpCas9	negative selection	2659376
161416823	161416846	2	-	27260157	HT1080	viability	GTAGCGGCTAGGGCTGCCGATGG	TBR1	ENSG00000136535	0.141724568432124	[]	[]	1	hSpCas9	negative selection	2661878
161416545	161416568	2	-	27260157	HT1080	viability	TCAAAGGTGAACTTCTCTCCAGG	TBR1	ENSG00000136535	0.159722379861922	[]	[]	1	hSpCas9	negative selection	2681078
161416471	161416494	2	+	27260157	HT1080	viability	AGCAGCAGCTACCCACATTCAGG	TBR1	ENSG00000136535	-0.774861313930213	[]	[]	-8	hSpCas9	negative selection	2681490
161416435	161416458	2	-	27260157	HT1080	viability	TTCTTGGAGAGCATGATAGAAGG	TBR1	ENSG00000136535	-0.205714582070372	[]	[]	0	hSpCas9	negative selection	2682950
161416499	161416522	2	-	27260157	HT1080	viability	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	-0.341227519497503	[]	[]	-7	hSpCas9	negative selection	2683442
161416482	161416505	2	-	27260157	HT1080	viability	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	-0.272215749217417	[]	[]	-4	hSpCas9	negative selection	2684298
161416850	161416873	2	-	27260157	HT1080	viability	GTTGGTGATGACCGGGTGGTGGG	TBR1	ENSG00000136535	-0.448628355631334	[]	[]	-7	hSpCas9	negative selection	2689196
161416522	161416545	2	-	27260157	HT1080	viability	TTGTCAGTGGTCGAGATAATGGG	TBR1	ENSG00000136535	-0.37703306910134	[]	[]	-7	hSpCas9	negative selection	2689861
161416523	161416546	2	-	27260157	HT1080	viability	GTTGTCAGTGGTCGAGATAATGG	TBR1	ENSG00000136535	-0.701582086637492	[]	[]	-8	hSpCas9	negative selection	2690383
161416527	161416550	2	+	27260157	HT1080	viability	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	-0.0590599191381282	[]	[]	0	hSpCas9	negative selection	2693191
161416535	161416558	2	-	27260157	HT1080	viability	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	0.938124377774976	[]	[]	7	hSpCas9	negative selection	2699529
161416428	161416451	2	-	27260157	HT1080	viability	AGAGCATGATAGAAGGAGAAAGG	TBR1	ENSG00000136535	0.740622348553699	[]	[]	6	hSpCas9	negative selection	2720656
161417044	161417067	2	-	27260157	HT1080	viability	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.0725857428915571	[]	[]	0	hSpCas9	negative selection	2724084
161417011	161417034	2	-	27260157	MKN45	viability	AGGTACACCTGTGCTTTGCCGGG	TBR1	ENSG00000136535	0.273805766548604	[]	[]	5	hSpCas9	negative selection	2727636
161416771	161416794	2	+	27260157	MKN45	viability	AGTGCCATGTTCCCGTACCCCGG	TBR1	ENSG00000136535	-0.20848048837148	[]	[]	0	hSpCas9	negative selection	2728645
161416833	161416856	2	-	27260157	MKN45	viability	GGTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.0596361772493018	[]	[]	0	hSpCas9	negative selection	2733569
161416684	161416707	2	+	27260157	MKN45	viability	GAGCTTCGTCACAGTTTCGATGG	TBR1	ENSG00000136535	-0.495906001804043	[]	[]	-6	hSpCas9	negative selection	2734412
161416451	161416474	2	-	27260157	MKN45	viability	GCTCACATTGAGAAATTTCTTGG	TBR1	ENSG00000136535	-0.497895097325858	[]	[]	-6	hSpCas9	negative selection	2735506
161416823	161416846	2	-	27260157	MKN45	viability	GTAGCGGCTAGGGCTGCCGATGG	TBR1	ENSG00000136535	0.903983621587819	[]	[]	8	hSpCas9	negative selection	2738008
161416545	161416568	2	-	27260157	MKN45	viability	TCAAAGGTGAACTTCTCTCCAGG	TBR1	ENSG00000136535	0.206156197550832	[]	[]	5	hSpCas9	negative selection	2757208
161416471	161416494	2	+	27260157	MKN45	viability	AGCAGCAGCTACCCACATTCAGG	TBR1	ENSG00000136535	0.376892903449276	[]	[]	6	hSpCas9	negative selection	2757620
161416435	161416458	2	-	27260157	MKN45	viability	TTCTTGGAGAGCATGATAGAAGG	TBR1	ENSG00000136535	0.426627959352149	[]	[]	6	hSpCas9	negative selection	2759080
161416499	161416522	2	-	27260157	MKN45	viability	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	0.582801185725021	[]	[]	7	hSpCas9	negative selection	2759572
161416482	161416505	2	-	27260157	MKN45	viability	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	0.696344881156212	[]	[]	7	hSpCas9	negative selection	2760428
161416850	161416873	2	-	27260157	MKN45	viability	GTTGGTGATGACCGGGTGGTGGG	TBR1	ENSG00000136535	-1.35154432703202	[]	[]	-8	hSpCas9	negative selection	2765326
161416522	161416545	2	-	27260157	MKN45	viability	TTGTCAGTGGTCGAGATAATGGG	TBR1	ENSG00000136535	0.0324027053896747	[]	[]	0	hSpCas9	negative selection	2765991
161416523	161416546	2	-	27260157	MKN45	viability	GTTGTCAGTGGTCGAGATAATGG	TBR1	ENSG00000136535	-0.0469021342332973	[]	[]	0	hSpCas9	negative selection	2766513
161416527	161416550	2	+	27260157	MKN45	viability	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.489214336591103	[]	[]	6	hSpCas9	negative selection	2769321
161416535	161416558	2	-	27260157	MKN45	viability	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	0.0634848443348275	[]	[]	0	hSpCas9	negative selection	2775659
161416428	161416451	2	-	27260157	MKN45	viability	AGAGCATGATAGAAGGAGAAAGG	TBR1	ENSG00000136535	0.505583693276312	[]	[]	6	hSpCas9	negative selection	2796786
161417044	161417067	2	-	27260157	MKN45	viability	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.512040646099502	[]	[]	6	hSpCas9	negative selection	2800214
161417011	161417034	2	-	27260157	RKO	viability	AGGTACACCTGTGCTTTGCCGGG	TBR1	ENSG00000136535	1.34018345564397	[]	[]	9	hSpCas9	negative selection	2803766
161416771	161416794	2	+	27260157	RKO	viability	AGTGCCATGTTCCCGTACCCCGG	TBR1	ENSG00000136535	0.377884314671001	[]	[]	2	hSpCas9	negative selection	2804775
161416833	161416856	2	-	27260157	RKO	viability	GGTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.258224828657236	[]	[]	1	hSpCas9	negative selection	2809699
161416684	161416707	2	+	27260157	RKO	viability	GAGCTTCGTCACAGTTTCGATGG	TBR1	ENSG00000136535	-0.458750732082647	[]	[]	-6	hSpCas9	negative selection	2810542
161416451	161416474	2	-	27260157	RKO	viability	GCTCACATTGAGAAATTTCTTGG	TBR1	ENSG00000136535	0.186741870661932	[]	[]	1	hSpCas9	negative selection	2811636
161416823	161416846	2	-	27260157	RKO	viability	GTAGCGGCTAGGGCTGCCGATGG	TBR1	ENSG00000136535	0.343271699024375	[]	[]	1	hSpCas9	negative selection	2814138
161416545	161416568	2	-	27260157	RKO	viability	TCAAAGGTGAACTTCTCTCCAGG	TBR1	ENSG00000136535	-0.565743412078416	[]	[]	-7	hSpCas9	negative selection	2833338
161416471	161416494	2	+	27260157	RKO	viability	AGCAGCAGCTACCCACATTCAGG	TBR1	ENSG00000136535	0.0820840478407825	[]	[]	0	hSpCas9	negative selection	2833750
161416435	161416458	2	-	27260157	RKO	viability	TTCTTGGAGAGCATGATAGAAGG	TBR1	ENSG00000136535	-0.0460679929945336	[]	[]	0	hSpCas9	negative selection	2835210
161416499	161416522	2	-	27260157	RKO	viability	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	1.09939084114843	[]	[]	9	hSpCas9	negative selection	2835702
161416482	161416505	2	-	27260157	RKO	viability	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	0.0525312749327915	[]	[]	0	hSpCas9	negative selection	2836558
161416850	161416873	2	-	27260157	RKO	viability	GTTGGTGATGACCGGGTGGTGGG	TBR1	ENSG00000136535	-0.510665600426614	[]	[]	-6	hSpCas9	negative selection	2841456
161416522	161416545	2	-	27260157	RKO	viability	TTGTCAGTGGTCGAGATAATGGG	TBR1	ENSG00000136535	-0.818267031645552	[]	[]	-7	hSpCas9	negative selection	2842121
161416523	161416546	2	-	27260157	RKO	viability	GTTGTCAGTGGTCGAGATAATGG	TBR1	ENSG00000136535	-0.605886037004554	[]	[]	-7	hSpCas9	negative selection	2842643
161416527	161416550	2	+	27260157	RKO	viability	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.708090907277298	[]	[]	8	hSpCas9	negative selection	2845451
161416535	161416558	2	-	27260157	RKO	viability	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	0.385271561883727	[]	[]	2	hSpCas9	negative selection	2851789
161416428	161416451	2	-	27260157	RKO	viability	AGAGCATGATAGAAGGAGAAAGG	TBR1	ENSG00000136535	0.408695718186554	[]	[]	2	hSpCas9	negative selection	2872916
161417044	161417067	2	-	27260157	RKO	viability	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.765591307627991	[]	[]	8	hSpCas9	negative selection	2876344
161417011	161417034	2	-	27260157	SF268	viability	AGGTACACCTGTGCTTTGCCGGG	TBR1	ENSG00000136535	1.4126128012517	[]	[]	9	hSpCas9	negative selection	2879896
161416771	161416794	2	+	27260157	SF268	viability	AGTGCCATGTTCCCGTACCCCGG	TBR1	ENSG00000136535	0.790975581577023	[]	[]	8	hSpCas9	negative selection	2880905
161416833	161416856	2	-	27260157	SF268	viability	GGTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	-0.169462408489585	[]	[]	-1	hSpCas9	negative selection	2885829
161416684	161416707	2	+	27260157	SF268	viability	GAGCTTCGTCACAGTTTCGATGG	TBR1	ENSG00000136535	-0.339917105496044	[]	[]	-3	hSpCas9	negative selection	2886672
161416451	161416474	2	-	27260157	SF268	viability	GCTCACATTGAGAAATTTCTTGG	TBR1	ENSG00000136535	0.67701189959556	[]	[]	8	hSpCas9	negative selection	2887766
161416823	161416846	2	-	27260157	SF268	viability	GTAGCGGCTAGGGCTGCCGATGG	TBR1	ENSG00000136535	0.420828954524328	[]	[]	4	hSpCas9	negative selection	2890268
161416545	161416568	2	-	27260157	SF268	viability	TCAAAGGTGAACTTCTCTCCAGG	TBR1	ENSG00000136535	-0.261455492792035	[]	[]	-2	hSpCas9	negative selection	2909468
161416471	161416494	2	+	27260157	SF268	viability	AGCAGCAGCTACCCACATTCAGG	TBR1	ENSG00000136535	0.564502171139017	[]	[]	8	hSpCas9	negative selection	2909880
161416435	161416458	2	-	27260157	SF268	viability	TTCTTGGAGAGCATGATAGAAGG	TBR1	ENSG00000136535	0.0594677478037969	[]	[]	0	hSpCas9	negative selection	2911340
161416499	161416522	2	-	27260157	SF268	viability	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	0.947486564435106	[]	[]	9	hSpCas9	negative selection	2911832
161416482	161416505	2	-	27260157	SF268	viability	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	0.820426390815705	[]	[]	8	hSpCas9	negative selection	2912688
161416850	161416873	2	-	27260157	SF268	viability	GTTGGTGATGACCGGGTGGTGGG	TBR1	ENSG00000136535	0.377556528801714	[]	[]	4	hSpCas9	negative selection	2917586
161416522	161416545	2	-	27260157	SF268	viability	TTGTCAGTGGTCGAGATAATGGG	TBR1	ENSG00000136535	-0.0813732101905022	[]	[]	0	hSpCas9	negative selection	2918251
161416523	161416546	2	-	27260157	SF268	viability	GTTGTCAGTGGTCGAGATAATGG	TBR1	ENSG00000136535	-0.368609958568231	[]	[]	-3	hSpCas9	negative selection	2918773
161416527	161416550	2	+	27260157	SF268	viability	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.952570763419415	[]	[]	9	hSpCas9	negative selection	2921581
161416535	161416558	2	-	27260157	SF268	viability	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	1.02402159263792	[]	[]	9	hSpCas9	negative selection	2927919
161416428	161416451	2	-	27260157	SF268	viability	AGAGCATGATAGAAGGAGAAAGG	TBR1	ENSG00000136535	-0.522200036084514	[]	[]	-4	hSpCas9	negative selection	2949046
161417044	161417067	2	-	27260157	SF268	viability	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	-0.270383564305437	[]	[]	-2	hSpCas9	negative selection	2952474
161416535	161416558	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	-0.5956634805983949	[3,3]	[2,0]	-7	hSpCas9	positive selection	3025749
161416983	161417006	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTTCTCCTCCACCCAGCCGGGG	TBR1	ENSG00000136535	-0.2904820371541744	[3,2]	[2,1]	-4	hSpCas9	positive selection	3025750
161416903	161416926	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTCGCCGCAGGGATACCCCACGG	TBR1	ENSG00000136535	-0.067946419263128	[2,2]	[0,3]	-1	hSpCas9	positive selection	3025751
161417078	161417101	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGATGATCATCACCAAACAGGG	TBR1	ENSG00000136535	0.2431579391411784	[3,3]	[3,3]	5	hSpCas9	positive selection	3025752
161416535	161416558	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	0.18601372930113644	[3,3]	[2,3]	3	hSpCas9	positive selection	3093607
161416983	161417006	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTTCTCCTCCACCCAGCCGGGG	TBR1	ENSG00000136535	-0.5291291280132921	[3,3]	[2,0]	-7	hSpCas9	positive selection	3093608
161416903	161416926	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTCGCCGCAGGGATACCCCACGG	TBR1	ENSG00000136535	-0.1711105925192663	[2,2]	[2,0]	-2	hSpCas9	positive selection	3093609
161417078	161417101	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGATGATCATCACCAAACAGGG	TBR1	ENSG00000136535	0.12165830721221503	[3,3]	[2,2]	2	hSpCas9	positive selection	3093610
161418202	161418225		+	24336571	A375	resistance to PLX after 7 days	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.02715771672359113	[17,15]	[18,14]	1	hSpCas9	positive selection	3149291
161416499	161416522		-	24336571	A375	resistance to PLX after 7 days	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	-0.0699899022411871	[10,12]	[11,10]	-2	hSpCas9	positive selection	3149292
161418251	161418274		+	24336571	A375	resistance to PLX after 7 days	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	-0.2704248505193937	[13,11]	[9,10]	-7	hSpCas9	positive selection	3149293
161416794	161416817		-	24336571	A375	resistance to PLX after 7 days	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.08300549037628152	[8,10]	[11,9]	3	hSpCas9	positive selection	3149295
161416684	161416707		+	24336571	A375	resistance to PLX after 7 days	GAGCTTCGTCACAGTTTCGATGG	TBR1	ENSG00000136535	0.33682996972318124	[7,7]	[8,10]	8	hSpCas9	positive selection	3149296
161418202	161418225		+	24336571	A375	resistance to PLX after 14 days	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.3204188495257344	[15,18]	[6,5]	-4	hSpCas9	positive selection	3207084
161416499	161416522		-	24336571	A375	resistance to PLX after 14 days	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	-1.0079376649703877	[15,16]	[3,2]	-9	hSpCas9	positive selection	3207085
161418251	161418274		+	24336571	A375	resistance to PLX after 14 days	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	-0.7432189537466402	[17,7]	[2,3]	-8	hSpCas9	positive selection	3207086
161416794	161416817		-	24336571	A375	resistance to PLX after 14 days	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.38388197592551215	[10,9]	[5,5]	4	hSpCas9	positive selection	3207088
161416684	161416707		+	24336571	A375	resistance to PLX after 14 days	GAGCTTCGTCACAGTTTCGATGG	TBR1	ENSG00000136535	1.7950556393102688	[6,5]	[10,9]	9	hSpCas9	positive selection	3207089
161418202	161418225		+	24336571	A375	viability after 7 days	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.14878253353154602	[15]	[17,15]	2	hSpCas9	negative selection	3264877
161416499	161416522		-	24336571	A375	viability after 7 days	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	0.3123194335613738	[9]	[10,12]	5	hSpCas9	negative selection	3264878
161418251	161418274		+	24336571	A375	viability after 7 days	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.7036211194994981	[7]	[13,11]	9	hSpCas9	negative selection	3264879
161416794	161416817		-	24336571	A375	viability after 7 days	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.6031658752647171	[6]	[8,10]	8	hSpCas9	negative selection	3264881
161416684	161416707		+	24336571	A375	viability after 7 days	GAGCTTCGTCACAGTTTCGATGG	TBR1	ENSG00000136535	0.10155031061611208	[7]	[7,7]	1	hSpCas9	negative selection	3264882
161418202	161418225		+	24336571	A375	viability after 14 days	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.22014859267728143	[15]	[15,18]	3	hSpCas9	negative selection	3322670
161416499	161416522		-	24336571	A375	viability after 14 days	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	0.7952963147013375	[9]	[15,16]	8	hSpCas9	negative selection	3322671
161418251	161418274		+	24336571	A375	viability after 14 days	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.7400541239499794	[7]	[17,7]	8	hSpCas9	negative selection	3322672
161416794	161416817		-	24336571	A375	viability after 14 days	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.610325216503603	[6]	[10,9]	7	hSpCas9	negative selection	3322674
161416684	161416707		+	24336571	A375	viability after 14 days	GAGCTTCGTCACAGTTTCGATGG	TBR1	ENSG00000136535	-0.1497323116369872	[7]	[6,5]	-2	hSpCas9	negative selection	3322675
161417809	161417832	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	1.529405756882636	[52,52]	[0,0]	6	hSpCas9	positive selection	3396407
161418251	161418274	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	-0.327636289275321	[191,191]	[0,0]	-2	hSpCas9	positive selection	3396408
161417720	161417743	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	0.8479352753081334	[84,84]	[0,0]	4	hSpCas9	positive selection	3396409
161416535	161416558	2	-	26780180	HT29	viability (Avana library 4 designs)	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	-0.12128328896337	[]	[]	-2	hSpCas9	negative selection	3464459
161416982	161417005	2	+	26780180	HT29	viability (Avana library 4 designs)	AGTTCTCCTCCACCCAGCCGGGG	TBR1	ENSG00000136535	1.81358608086321	[]	[]	7	hSpCas9	negative selection	3464460
161416902	161416925	2	+	26780180	HT29	viability (Avana library 4 designs)	CTCGCCGCAGGGATACCCCACGG	TBR1	ENSG00000136535	1.30740125771246	[]	[]	5	hSpCas9	negative selection	3464461
161417077	161417100	2	+	26780180	HT29	viability (Avana library 4 designs)	GAGATGATCATCACCAAACAGGG	TBR1	ENSG00000136535	0.920274408748624	[]	[]	3	hSpCas9	negative selection	3464462
161416982	161417005	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTTCTCCTCCACCCAGCCGGGG	TBR1	ENSG00000136535	4.15901980054776	[]	[]	7	hSpCas9	negative selection	3567164
161416535	161416558	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	4.57240649107669	[]	[]	7	hSpCas9	negative selection	3567165
161417077	161417100	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGATGATCATCACCAAACAGGG	TBR1	ENSG00000136535	-6.03029024113057	[]	[]	-6	hSpCas9	negative selection	3567166
161416902	161416925	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTCGCCGCAGGGATACCCCACGG	TBR1	ENSG00000136535	5.68584350582083	[]	[]	8	hSpCas9	negative selection	3567167
161416562	161416585	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTGAAAAAAATTACCAGGGGG	TBR1	ENSG00000136535	-5.55331265508791	[]	[]	-6	hSpCas9	negative selection	3567168
161416482	161416505	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	4.84842997463441	[]	[]	8	hSpCas9	negative selection	3567169
161416982	161417005	2	+	26780180	A375	viability (Avana lentiGuide)	AGTTCTCCTCCACCCAGCCGGGG	TBR1	ENSG00000136535	-0.1498150523602	[]	[]	0	hSpCas9	negative selection	3675823
161416535	161416558	2	-	26780180	A375	viability (Avana lentiGuide)	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	-1.77489210577293	[]	[]	-3	hSpCas9	negative selection	3675824
161417077	161417100	2	+	26780180	A375	viability (Avana lentiGuide)	GAGATGATCATCACCAAACAGGG	TBR1	ENSG00000136535	4.44364779984519	[]	[]	4	hSpCas9	negative selection	3675825
161416902	161416925	2	+	26780180	A375	viability (Avana lentiGuide)	CTCGCCGCAGGGATACCCCACGG	TBR1	ENSG00000136535	-0.676535510552416	[]	[]	-1	hSpCas9	negative selection	3675826
161416562	161416585	2	+	26780180	A375	viability (Avana lentiGuide)	CTTTGAAAAAAATTACCAGGGGG	TBR1	ENSG00000136535	4.8035868506098	[]	[]	4	hSpCas9	negative selection	3675827
161416482	161416505	2	-	26780180	A375	viability (Avana lentiGuide)	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	3.96303927805104	[]	[]	4	hSpCas9	negative selection	3675828
161416982	161417005	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTTCTCCTCCACCCAGCCGGGG	TBR1	ENSG00000136535	0.03151602011348345	[4]	[4,3]	0	hSpCas9	positive selection	3784430
161416535	161416558	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	0.1028241342957577	[5]	[5,5]	2	hSpCas9	positive selection	3784431
161417077	161417100	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGATGATCATCACCAAACAGGG	TBR1	ENSG00000136535	-0.7273746573466595	[5]	[3,2]	-8	hSpCas9	positive selection	3784432
161416902	161416925	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCGCCGCAGGGATACCCCACGG	TBR1	ENSG00000136535	0.14696058252510566	[3]	[3,4]	4	hSpCas9	positive selection	3784433
161416562	161416585	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTGAAAAAAATTACCAGGGGG	TBR1	ENSG00000136535	-0.9515704797703235	[5]	[2,1]	-8	hSpCas9	positive selection	3784434
161416482	161416505	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	0.25216255373063823	[4]	[5,5]	7	hSpCas9	positive selection	3784435
161416982	161417005	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTTCTCCTCCACCCAGCCGGGG	TBR1	ENSG00000136535	-0.3510206292895598	[5]	[2,3]	-4	hSpCas9	positive selection	3893037
161416535	161416558	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTTCTCTCCAGGTTGTCAGTGG	TBR1	ENSG00000136535	-0.027630968545854624	[5]	[5,2]	0	hSpCas9	positive selection	3893038
161417077	161417100	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGATGATCATCACCAAACAGGG	TBR1	ENSG00000136535	-0.7221422385942224	[5]	[1,2]	-7	hSpCas9	positive selection	3893039
161416902	161416925	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCGCCGCAGGGATACCCCACGG	TBR1	ENSG00000136535	0.35913809716555717	[3]	[5,3]	9	hSpCas9	positive selection	3893040
161416562	161416585	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTGAAAAAAATTACCAGGGGG	TBR1	ENSG00000136535	0.21775879972499892	[4]	[3,5]	5	hSpCas9	positive selection	3893041
161416482	161416505	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	-0.056175466999052896	[5]	[4,3]	-1	hSpCas9	positive selection	3893042
161417720	161417743	2	-	26780180	A375	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	0.611497956793258	[]	[]	2	hSpCas9	negative selection	4002439
161417809	161417832	2	+	26780180	A375	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	0.623801547883742	[]	[]	2	hSpCas9	negative selection	4002440
161418202	161418225	2	+	26780180	A375	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	1.40731117132967	[]	[]	7	hSpCas9	negative selection	4002441
161418251	161418274	2	+	26780180	A375	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.554987963555437	[]	[]	1	hSpCas9	negative selection	4002442
161416794	161416817	2	-	26780180	A375	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.814364609763229	[]	[]	3	hSpCas9	negative selection	4002443
161416939	161416962	2	-	26780180	A375	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.473347891481404	[]	[]	1	hSpCas9	negative selection	4002444
161417720	161417743	2	-	26780180	HT29	viability (GeCKOv2 library)	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	1.52162777487208	[]	[]	7	hSpCas9	negative selection	4110405
161417809	161417832	2	+	26780180	HT29	viability (GeCKOv2 library)	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	1.61397023911937	[]	[]	8	hSpCas9	negative selection	4110406
161418202	161418225	2	+	26780180	HT29	viability (GeCKOv2 library)	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	1.88202662030148	[]	[]	9	hSpCas9	negative selection	4110407
161418251	161418274	2	+	26780180	HT29	viability (GeCKOv2 library)	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.843157173497676	[]	[]	3	hSpCas9	negative selection	4110408
161416794	161416817	2	-	26780180	HT29	viability (GeCKOv2 library)	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	1.2992337708078	[]	[]	6	hSpCas9	negative selection	4110409
161416939	161416962	2	-	26780180	HT29	viability (GeCKOv2 library)	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	1.27533107989864	[]	[]	6	hSpCas9	negative selection	4110410
161418202	161418225	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.09753978897416295	[3]	[2,2]	2	hSpCas9	positive selection	4175624
161416499	161416522	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	-0.2205259139537123	[3]	[2,1]	-5	hSpCas9	positive selection	4175625
161418251	161418274	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.21149373169694208	[3]	[3,1]	5	hSpCas9	positive selection	4175626
161416794	161416817	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.013909118703966827	[3]	[1,2]	0	hSpCas9	positive selection	4175628
161416684	161416707	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGCTTCGTCACAGTTTCGATGG	TBR1	ENSG00000136535	0.5681256480439261	[2]	[1,3]	9	hSpCas9	positive selection	4175629
161418202	161418225	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.3384564215099942	[3]	[1,1,0,0]	-5	hSpCas9	positive selection	4239646
161416499	161416522	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGATCGTGCAAGACAAGCTCGG	TBR1	ENSG00000136535	1.106983171834367	[3]	[3,1,2,4]	8	hSpCas9	positive selection	4239647
161418251	161418274	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	-0.020432792839922886	[2]	[0,1,1,0]	0	hSpCas9	positive selection	4239648
161416794	161416817	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.1283290470534438	[3]	[1,3,1,0]	1	hSpCas9	positive selection	4239650
161416684	161416707	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGCTTCGTCACAGTTTCGATGG	TBR1	ENSG00000136535	0.6158403953517667	[2]	[2,3,1,0]	4	hSpCas9	positive selection	4239651
161416794	161416817	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.32785939570362677	[1]	[1,0]	-6	hSpCas9	positive selection	4302253
161418202	161418225	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.3395091054161473	[2]	[2,0]	-6	hSpCas9	positive selection	4302254
161416939	161416962	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.32660627520927005	[3]	[3,2]	6	hSpCas9	positive selection	4302255
161417809	161417832	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.2093418802237892	[1]	[1,0]	-4	hSpCas9	positive selection	4366507
161418251	161418274	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.11472266608983965	[2]	[3,1]	2	hSpCas9	positive selection	4366508
161417720	161417743	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	0.36750260110796745	[2]	[1,2]	7	hSpCas9	positive selection	4366509
161416577	161416599	2	-	27760321	OCIAML3	viability	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	0.024063195605061538	[679,565]	[488,498]	0	hSpCas9	negative selection	4445679
161416833	161416855	2	-	27760321	OCIAML3	viability	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.7793618297400542	[571,418]	[588,749]	8	hSpCas9	negative selection	4445680
161416854	161416876	2	-	27760321	OCIAML3	viability	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.6269855524217023	[603,555]	[597,833]	7	hSpCas9	negative selection	4445681
161417800	161417822	2	-	27760321	OCIAML3	viability	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.19723542285773976	[1107,1027]	[880,1057]	2	hSpCas9	negative selection	4445682
161418203	161418225	2	+	27760321	OCIAML3	viability	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.32677653033691284	[353,281]	[204,446]	4	hSpCas9	negative selection	4445683
161416577	161416599	2	-	27760321	OCIAML2	viability	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	-0.35028765663340455	[679,565]	[337,466]	-4	hSpCas9	negative selection	4529142
161416833	161416855	2	-	27760321	OCIAML2	viability	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.5760856887624352	[571,418]	[430,803]	7	hSpCas9	negative selection	4529143
161416854	161416876	2	-	27760321	OCIAML2	viability	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.4382378899173834	[603,555]	[579,708]	6	hSpCas9	negative selection	4529144
161417800	161417822	2	-	27760321	OCIAML2	viability	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.27591831838708014	[1107,1027]	[962,1155]	3	hSpCas9	negative selection	4529145
161418203	161418225	2	+	27760321	OCIAML2	viability	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.6217439839857408	[353,281]	[160,172]	-6	hSpCas9	negative selection	4529146
161416577	161416599	2	-	27760321	MV411	viability	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	-0.6546004916901509	[679,565]	[90,513]	-4	hSpCas9	negative selection	4612605
161416833	161416855	2	-	27760321	MV411	viability	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.5489371464616293	[571,418]	[333,683]	4	hSpCas9	negative selection	4612606
161416854	161416876	2	-	27760321	MV411	viability	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.7469576902655504	[603,555]	[720,523]	5	hSpCas9	negative selection	4612607
161417800	161417822	2	-	27760321	MV411	viability	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.13374442990859148	[1107,1027]	[527,1141]	0	hSpCas9	negative selection	4612608
161418203	161418225	2	+	27760321	MV411	viability	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.8292859299530297	[353,281]	[110,126]	-5	hSpCas9	negative selection	4612609
161416577	161416599	2	-	27760321	HL60	viability	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	0.43632299073017067	[679,565]	[510,870]	5	hSpCas9	negative selection	4696068
161416833	161416855	2	-	27760321	HL60	viability	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.7196668262388604	[571,418]	[570,754]	8	hSpCas9	negative selection	4696069
161416854	161416876	2	-	27760321	HL60	viability	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.7750914405596261	[603,555]	[833,785]	8	hSpCas9	negative selection	4696070
161417800	161417822	2	-	27760321	HL60	viability	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.15070815025427997	[1107,1027]	[1057,873]	1	hSpCas9	negative selection	4696071
161418203	161418225	2	+	27760321	HL60	viability	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-1.194124890019403	[353,281]	[140,82]	-8	hSpCas9	negative selection	4696072
161416577	161416599	2	-	27760321	HT1080	viability	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	-1.3818799613776442	[565,441]	[77,75]	-5	hSpCas9	negative selection	4779531
161416833	161416855	2	-	27760321	HT1080	viability	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	1.5443931740144714	[418,326]	[536,319]	8	hSpCas9	negative selection	4779532
161416854	161416876	2	-	27760321	HT1080	viability	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.6728362265419403	[555,433]	[416,201]	3	hSpCas9	negative selection	4779533
161417800	161417822	2	-	27760321	HT1080	viability	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.3951657449978636	[1027,801]	[549,401]	2	hSpCas9	negative selection	4779534
161418203	161418225	2	+	27760321	HT1080	viability	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.09763635458640102	[281,219]	[169,37]	0	hSpCas9	negative selection	4779535
161416577	161416599	2	-	27760321	HT29	viability after 7 days	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	-0.24818453062402765	[565,441]	[541,626,468]	-4	hSpCas9	negative selection	4862994
161416833	161416855	2	-	27760321	HT29	viability after 7 days	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.564039417702815	[418,326]	[888,787,481]	8	hSpCas9	negative selection	4862995
161416854	161416876	2	-	27760321	HT29	viability after 7 days	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.06433994061678322	[555,433]	[1037,518,496]	1	hSpCas9	negative selection	4862996
161417800	161417822	2	-	27760321	HT29	viability after 7 days	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	-0.1716598989403293	[1027,801]	[1156,1237,761]	-3	hSpCas9	negative selection	4862997
161418203	161418225	2	+	27760321	HT29	viability after 7 days	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.40555455914189353	[281,219]	[283,167,282]	-5	hSpCas9	negative selection	4862998
161416577	161416599	2	-	27760321	HT29	viability after 25 days	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	-0.25262136511698496	[565,441]	[412,377,683]	-3	hSpCas9	negative selection	4946457
161416833	161416855	2	-	27760321	HT29	viability after 25 days	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.6232266569848725	[418,326]	[605,622,752]	7	hSpCas9	negative selection	4946458
161416854	161416876	2	-	27760321	HT29	viability after 25 days	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.14301741743963164	[555,433]	[672,709,470]	1	hSpCas9	negative selection	4946459
161417800	161417822	2	-	27760321	HT29	viability after 25 days	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.2797570768411841	[1027,801]	[1085,1090,1683]	3	hSpCas9	negative selection	4946460
161418203	161418225	2	+	27760321	HT29	viability after 25 days	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.41280686682388656	[281,219]	[333,145,151]	-4	hSpCas9	negative selection	4946461
161416577	161416599	2	-	27760321	HT29	viability after 22 days	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	-0.6187043516598439	[565,441]	[206,456,479]	-5	hSpCas9	negative selection	5029920
161416833	161416855	2	-	27760321	HT29	viability after 22 days	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.5700814139870022	[418,326]	[504,479,941]	6	hSpCas9	negative selection	5029921
161416854	161416876	2	-	27760321	HT29	viability after 22 days	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.350127316573791	[555,433]	[838,543,802]	4	hSpCas9	negative selection	5029922
161417800	161417822	2	-	27760321	HT29	viability after 22 days	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.1990745660476405	[1027,801]	[1136,1276,1230]	2	hSpCas9	negative selection	5029923
161418203	161418225	2	+	27760321	HT29	viability after 22 days	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.7717031676734346	[281,219]	[254,140,110]	-6	hSpCas9	negative selection	5029924
161416577	161416599	2	-	27760321	HT29	viability after 19 days	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	-0.4582376095350651	[565,441]	[576,521,184]	-4	hSpCas9	negative selection	5113383
161416833	161416855	2	-	27760321	HT29	viability after 19 days	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.047715491322575077	[418,326]	[544,309,476]	0	hSpCas9	negative selection	5113384
161416854	161416876	2	-	27760321	HT29	viability after 19 days	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.3743463370296695	[555,433]	[844,776,595]	3	hSpCas9	negative selection	5113385
161417800	161417822	2	-	27760321	HT29	viability after 19 days	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.2600503496936848	[1027,801]	[1233,1522,1008]	2	hSpCas9	negative selection	5113386
161418203	161418225	2	+	27760321	HT29	viability after 19 days	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.17353659283735146	[281,219]	[143,223,378]	-2	hSpCas9	negative selection	5113387
161416577	161416599	2	-	27760321	HT29	viability after 16 days	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	0.19169187914516034	[565,441]	[807,508,633]	2	hSpCas9	negative selection	5196846
161416833	161416855	2	-	27760321	HT29	viability after 16 days	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.6428258851537993	[418,326]	[633,612,706]	7	hSpCas9	negative selection	5196847
161416854	161416876	2	-	27760321	HT29	viability after 16 days	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.5583850114291122	[555,433]	[904,929,616]	6	hSpCas9	negative selection	5196848
161417800	161417822	2	-	27760321	HT29	viability after 16 days	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.28597645699841867	[1027,801]	[1066,1286,1371]	3	hSpCas9	negative selection	5196849
161418203	161418225	2	+	27760321	HT29	viability after 16 days	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.8455182556787361	[281,219]	[289,57,135]	-6	hSpCas9	negative selection	5196850
161416577	161416599	2	-	27760321	HT29	viability after 13 days	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	-0.2100125557341282	[565,441]	[636,439,442]	-2	hSpCas9	negative selection	5280309
161416833	161416855	2	-	27760321	HT29	viability after 13 days	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.6129285518360912	[418,326]	[698,587,695]	7	hSpCas9	negative selection	5280310
161416854	161416876	2	-	27760321	HT29	viability after 13 days	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.4865235318920919	[555,433]	[992,817,613]	6	hSpCas9	negative selection	5280311
161417800	161417822	2	-	27760321	HT29	viability after 13 days	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.08047203587584084	[1027,801]	[1192,885,1277]	1	hSpCas9	negative selection	5280312
161418203	161418225	2	+	27760321	HT29	viability after 13 days	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.02570222073019357	[281,219]	[507,242,146]	0	hSpCas9	negative selection	5280313
161416577	161416599	2	-	27760321	HT29	viability after 10 days	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	-0.11611150733582104	[565,441]	[570,608,562]	-1	hSpCas9	negative selection	5363772
161416833	161416855	2	-	27760321	HT29	viability after 10 days	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	0.5932977326644339	[418,326]	[801,783,527]	7	hSpCas9	negative selection	5363773
161416854	161416876	2	-	27760321	HT29	viability after 10 days	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	0.13873958991381213	[555,433]	[567,566,897]	1	hSpCas9	negative selection	5363774
161417800	161417822	2	-	27760321	HT29	viability after 10 days	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.24507186643986056	[1027,801]	[1293,1309,1453]	3	hSpCas9	negative selection	5363775
161418203	161418225	2	+	27760321	HT29	viability after 10 days	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.6107434027921065	[281,219]	[275,140,196]	-6	hSpCas9	negative selection	5363776
161416577	161416599	2	-	27760321	MOLM13	viability	GACTGATTCGTCATCCCCCTGG	TBR1	ENSG00000136535	0.7001661371470189	[679,565]	[384,724]	5	hSpCas9	negative selection	5447235
161416833	161416855	2	-	27760321	MOLM13	viability	GTGGGCCATGTAGCGGCTAGGG	TBR1	ENSG00000136535	1.1383859018256632	[571,418]	[385,799]	7	hSpCas9	negative selection	5447236
161416854	161416876	2	-	27760321	MOLM13	viability	TCCGTTGGTGATGACCGGGTGG	TBR1	ENSG00000136535	-0.04144705950990957	[603,555]	[486,173]	0	hSpCas9	negative selection	5447237
161417800	161417822	2	-	27760321	MOLM13	viability	TGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.8632871569724285	[1107,1027]	[848,1306]	6	hSpCas9	negative selection	5447238
161418203	161418225	2	+	27760321	MOLM13	viability	AATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.173572052962581	[353,281]	[21,273]	-1	hSpCas9	negative selection	5447239
161416785	161416808	2	+	27661255	K562	viability	GTACCCCGGCCAGCACGGACCGG	TBR1	ENSG00000136535	-0.14133398815851145	[969,787]	[726,563]	-5	dCas9-KRAB	negative selection	5516231
161416482	161416505	2	-	27661255	K562	viability	GCTCGGATCCGCCTGAATGTGGG	TBR1	ENSG00000136535	0.16948597556995976	[600,773]	[704,537]	6	dCas9-KRAB	negative selection	5516232
161416794	161416817	2	-	27260156	BXPC3	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.3200418009564008	[96]	[80,117,96,226]	7	hSpCas9	negative selection	5574713
161418202	161418225	2	+	27260156	BXPC3	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.37993128112393276	[356]	[215,355,273,304]	-7	hSpCas9	negative selection	5574714
161416939	161416962	2	-	27260156	BXPC3	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.11022440526648342	[538]	[542,599,743,543]	2	hSpCas9	negative selection	5574715
161417809	161417832	2	+	27260156	BXPC3	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.13569443158275063	[163]	[147,144,143,191]	-3	hSpCas9	negative selection	5638967
161418251	161418274	2	+	27260156	BXPC3	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.11598242575358869	[445]	[554,419,463,587]	2	hSpCas9	negative selection	5638968
161417720	161417743	2	-	27260156	BXPC3	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.09716888392383916	[203]	[182,254,138,218]	-2	hSpCas9	negative selection	5638969
161416794	161416817	2	-	27260156	A673	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.3614569042579232	[96]	[210,112,138,142]	8	hSpCas9	negative selection	5695964
161418202	161418225	2	+	27260156	A673	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.3362257021667184	[356]	[334,385,297,336]	-7	hSpCas9	negative selection	5695965
161416939	161416962	2	-	27260156	A673	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.053651217147952346	[538]	[732,617,641,702]	1	hSpCas9	negative selection	5695966
161417809	161417832	2	+	27260156	A673	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.3791181641153505	[163]	[167,136,145,156]	-7	hSpCas9	negative selection	5760218
161418251	161418274	2	+	27260156	A673	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.07068056583093119	[445]	[543,452,529,731]	1	hSpCas9	negative selection	5760219
161417720	161417743	2	-	27260156	A673	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.35756331340546765	[203]	[190,198,170,203]	-7	hSpCas9	negative selection	5760220
161416794	161416817	2	-	27260156	A375	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.3494510374523614	[96]	[83,33,152,77]	-5	hSpCas9	negative selection	5817215
161418202	161418225	2	+	27260156	A375	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.36044349176308144	[356]	[441,769,551,420]	5	hSpCas9	negative selection	5817216
161416939	161416962	2	-	27260156	A375	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.2691978875622284	[538]	[905,761,695,678]	4	hSpCas9	negative selection	5817217
161417809	161417832	2	+	27260156	A375	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.3228951910719702	[163]	[195,170,59,183]	-4	hSpCas9	negative selection	5881469
161418251	161418274	2	+	27260156	A375	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.35596810156899267	[445]	[649,868,633,552]	5	hSpCas9	negative selection	5881470
161417720	161417743	2	-	27260156	A375	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.25370325780658654	[203]	[223,187,220,167]	-4	hSpCas9	negative selection	5881471
161416794	161416817	2	-	27260156	COLO741	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.03375439628857535	[96]	[108,62,184]	0	hSpCas9	negative selection	5938466
161418202	161418225	2	+	27260156	COLO741	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.10947231566720311	[356]	[511,355,407]	-2	hSpCas9	negative selection	5938467
161416939	161416962	2	-	27260156	COLO741	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.09110478889202156	[538]	[818,762,631]	2	hSpCas9	negative selection	5938468
161417809	161417832	2	+	27260156	COLO741	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.749728920471632	[163]	[118,113,138]	-9	hSpCas9	negative selection	6002720
161418251	161418274	2	+	27260156	COLO741	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.27761609064184634	[445]	[637,717,708]	6	hSpCas9	negative selection	6002721
161417720	161417743	2	-	27260156	COLO741	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.4422540027615798	[203]	[280,172,132]	-7	hSpCas9	negative selection	6002722
161416794	161416817	2	-	27260156	CAL120	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.7032408126368659	[96]	[52,80,84]	-7	hSpCas9	negative selection	6059717
161418202	161418225	2	+	27260156	CAL120	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.22041537338837552	[356]	[379,350,411]	-3	hSpCas9	negative selection	6059718
161416939	161416962	2	-	27260156	CAL120	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	-0.2107952942181272	[538]	[785,433,549]	-3	hSpCas9	negative selection	6059719
161417809	161417832	2	+	27260156	CAL120	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.34529185140690877	[163]	[205,83,197]	-5	hSpCas9	negative selection	6123971
161418251	161418274	2	+	27260156	CAL120	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.691897939098842	[445]	[746,700,1212]	8	hSpCas9	negative selection	6123972
161417720	161417743	2	-	27260156	CAL120	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	0.30420898480156344	[203]	[696,159,143]	4	hSpCas9	negative selection	6123973
161416794	161416817	2	-	27260156	CADOES1	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.5659696480555976	[96]	[92,139,175,124]	8	hSpCas9	negative selection	6180968
161418202	161418225	2	+	27260156	CADOES1	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.15411836448603727	[356]	[333,228,339,289]	-3	hSpCas9	negative selection	6180969
161416939	161416962	2	-	27260156	CADOES1	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.030574248066784132	[538]	[636,448,467,492]	0	hSpCas9	negative selection	6180970
161417809	161417832	2	+	27260156	CADOES1	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	0.19649671564416082	[163]	[131,140,280,143]	3	hSpCas9	negative selection	6245222
161418251	161418274	2	+	27260156	CADOES1	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.368489285848587	[445]	[589,479,352,725]	6	hSpCas9	negative selection	6245223
161417720	161417743	2	-	27260156	CADOES1	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.038698832804912486	[203]	[153,118,223,243]	0	hSpCas9	negative selection	6245224
161416794	161416817	2	-	27260156	EWS502	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.14573545181630276	[96]	[69,72,128,103]	-3	hSpCas9	negative selection	6302219
161418202	161418225	2	+	27260156	EWS502	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.4962052476479037	[356]	[163,321,256,343]	-7	hSpCas9	negative selection	6302220
161416939	161416962	2	-	27260156	EWS502	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.10411190264823861	[538]	[517,717,631,589]	1	hSpCas9	negative selection	6302221
161417809	161417832	2	+	27260156	EWS502	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	0.09044310804600775	[163]	[188,179,180,188]	1	hSpCas9	negative selection	6366473
161418251	161418274	2	+	27260156	EWS502	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.5753702882489234	[445]	[802,615,553,838]	8	hSpCas9	negative selection	6366474
161417720	161417743	2	-	27260156	EWS502	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.32936843563302576	[203]	[164,95,200,233]	-5	hSpCas9	negative selection	6366475
161416794	161416817	2	-	27260156	EW8	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.32731189295453955	[96]	[139,75,102,78]	6	hSpCas9	negative selection	6423470
161418202	161418225	2	+	27260156	EW8	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.043787540489275745	[356]	[259,284,277,296]	-1	hSpCas9	negative selection	6423471
161416939	161416962	2	-	27260156	EW8	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.3095771542557278	[538]	[574,662,490,447]	5	hSpCas9	negative selection	6423472
161417809	161417832	2	+	27260156	EW8	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	0.10625557148103892	[163]	[69,128,187,168]	2	hSpCas9	negative selection	6487724
161418251	161418274	2	+	27260156	EW8	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.030921748939996725	[445]	[435,355,323,374]	0	hSpCas9	negative selection	6487725
161417720	161417743	2	-	27260156	EW8	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.44991463584975944	[203]	[119,99,141,117]	-7	hSpCas9	negative selection	6487726
161416794	161416817	2	-	27260156	CORL105	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.9234473712321773	[96]	[162,193,291,222]	9	hSpCas9	negative selection	6544721
161418202	161418225	2	+	27260156	CORL105	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.07888068160436557	[356]	[306,361,565,371]	-1	hSpCas9	negative selection	6544722
161416939	161416962	2	-	27260156	CORL105	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.09390375703309572	[538]	[533,599,1002,604]	1	hSpCas9	negative selection	6544723
161417809	161417832	2	+	27260156	CORL105	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.2188488630120835	[163]	[181,125,201,156]	-4	hSpCas9	negative selection	6608975
161418251	161418274	2	+	27260156	CORL105	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.19505385372811318	[445]	[541,587,724,553]	3	hSpCas9	negative selection	6608976
161417720	161417743	2	-	27260156	CORL105	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.4009786825740771	[203]	[209,143,198,174]	-6	hSpCas9	negative selection	6608977
161416794	161416817	2	-	27260156	HS294T	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.18189082835129788	[96]	[41,25,32,29]	-3	hSpCas9	negative selection	6665972
161418202	161418225	2	+	27260156	HS294T	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.29428501687310255	[356]	[167,103,176,241]	4	hSpCas9	negative selection	6665973
161416939	161416962	2	-	27260156	HS294T	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.38307835921890404	[538]	[205,218,244,454]	5	hSpCas9	negative selection	6665974
161417809	161417832	2	+	27260156	HS294T	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.9878545583237983	[163]	[34,26,31,33]	-8	hSpCas9	negative selection	6730226
161418251	161418274	2	+	27260156	HS294T	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.3655154275259468	[445]	[221,272,199,184]	5	hSpCas9	negative selection	6730227
161417720	161417743	2	-	27260156	HS294T	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.4512350721222764	[203]	[35,25,42,142]	-6	hSpCas9	negative selection	6730228
161416794	161416817	2	-	27260156	HCC44	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.10999355427539159	[96]	[92,120,146,113]	1	hSpCas9	negative selection	6787223
161418202	161418225	2	+	27260156	HCC44	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.05984954124360703	[356]	[550,296,358,362]	-1	hSpCas9	negative selection	6787224
161416939	161416962	2	-	27260156	HCC44	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	-0.07380486052601219	[538]	[663,433,785,494]	-1	hSpCas9	negative selection	6787225
161417809	161417832	2	+	27260156	HCC44	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.6897243203328665	[163]	[60,163,37,168]	-7	hSpCas9	negative selection	6851477
161418251	161418274	2	+	27260156	HCC44	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.40905160718614825	[445]	[564,403,1034,757]	6	hSpCas9	negative selection	6851478
161417720	161417743	2	-	27260156	HCC44	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.8080371500229573	[203]	[166,123,105,128]	-8	hSpCas9	negative selection	6851479
161416794	161416817	2	-	27260156	G402	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.17083391866911457	[96]	[116,158,64,84]	-2	hSpCas9	negative selection	6908474
161418202	161418225	2	+	27260156	G402	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.09983740715011813	[356]	[543,391,419,292]	-1	hSpCas9	negative selection	6908475
161416939	161416962	2	-	27260156	G402	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.2938366021609072	[538]	[1343,702,576,675]	3	hSpCas9	negative selection	6908476
161417809	161417832	2	+	27260156	G402	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.25324421614302084	[163]	[259,25,179,207]	-3	hSpCas9	negative selection	6972728
161418251	161418274	2	+	27260156	G402	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.5750530264451152	[445]	[870,900,761,723]	7	hSpCas9	negative selection	6972729
161417720	161417743	2	-	27260156	G402	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.17675218241756507	[203]	[262,192,152,272]	-2	hSpCas9	negative selection	6972730
161416794	161416817	2	-	27260156	L33	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.33933831670097625	[96]	[53,76,92,102]	7	hSpCas9	negative selection	7029725
161418202	161418225	2	+	27260156	L33	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.35079014580918194	[356]	[406,94,153,232]	-7	hSpCas9	negative selection	7029726
161416939	161416962	2	-	27260156	L33	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.11944577197407297	[538]	[532,228,348,694]	2	hSpCas9	negative selection	7029727
161417809	161417832	2	+	27260156	L33	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.40570394238999774	[163]	[116,57,96,82]	-7	hSpCas9	negative selection	7093979
161418251	161418274	2	+	27260156	L33	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	-0.07235020938742631	[445]	[389,143,314,454]	-2	hSpCas9	negative selection	7093980
161417720	161417743	2	-	27260156	L33	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.6006037809981648	[203]	[90,65,80,157]	-8	hSpCas9	negative selection	7093981
161416794	161416817	2	-	27260156	K562	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.5112264628268375	[96]	[97,24,53,64]	-6	hSpCas9	negative selection	7150976
161418202	161418225	2	+	27260156	K562	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.15466896321198498	[356]	[231,378,477,315]	2	hSpCas9	negative selection	7150977
161416939	161416962	2	-	27260156	K562	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.1305381541791537	[538]	[692,493,416,502]	1	hSpCas9	negative selection	7150978
161417809	161417832	2	+	27260156	K562	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	0.1717192397134557	[163]	[134,56,101,332]	2	hSpCas9	negative selection	7215230
161418251	161418274	2	+	27260156	K562	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.5074831292355383	[445]	[572,649,697,356]	6	hSpCas9	negative selection	7215231
161417720	161417743	2	-	27260156	K562	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	0.1644682296585811	[203]	[281,329,113,108]	2	hSpCas9	negative selection	7215232
161416794	161416817	2	-	27260156	HT29	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.1068041826556847	[96]	[129,106,95,105]	-2	hSpCas9	negative selection	7272227
161418202	161418225	2	+	27260156	HT29	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.3218414283957564	[356]	[369,391,274,353]	-6	hSpCas9	negative selection	7272228
161416939	161416962	2	-	27260156	HT29	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	-0.03459665608453283	[538]	[707,834,589,464]	0	hSpCas9	negative selection	7272229
161417809	161417832	2	+	27260156	HT29	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.19127462704070375	[163]	[158,198,182,158]	-4	hSpCas9	negative selection	7336481
161418251	161418274	2	+	27260156	HT29	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.16612482910625742	[445]	[649,707,683,421]	3	hSpCas9	negative selection	7336482
161417720	161417743	2	-	27260156	HT29	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.347345370438056	[203]	[344,215,110,127]	-6	hSpCas9	negative selection	7336483
161416794	161416817	2	-	27260156	MHHES1	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.29947547153253096	[96]	[103,89,87,75]	-5	hSpCas9	negative selection	7393478
161418202	161418225	2	+	27260156	MHHES1	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.17442340540233786	[356]	[361,740,384,356]	3	hSpCas9	negative selection	7393479
161416939	161416962	2	-	27260156	MHHES1	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.1360537638702256	[538]	[628,731,795,530]	2	hSpCas9	negative selection	7393480
161417809	161417832	2	+	27260156	MHHES1	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.6652436103434374	[163]	[139,204,71,68]	-8	hSpCas9	negative selection	7457732
161418251	161418274	2	+	27260156	MHHES1	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.4990368797720475	[445]	[914,708,818,463]	8	hSpCas9	negative selection	7457733
161417720	161417743	2	-	27260156	MHHES1	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	0.12666369015911227	[203]	[336,275,313,115]	2	hSpCas9	negative selection	7457734
161416794	161416817	2	-	27260156	MEWO	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.02681079738220804	[96]	[117,51,102]	0	hSpCas9	negative selection	7514729
161418202	161418225	2	+	27260156	MEWO	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.5716856008296651	[356]	[223,219,229]	-8	hSpCas9	negative selection	7514730
161416939	161416962	2	-	27260156	MEWO	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.03725148664095354	[538]	[510,518,520]	0	hSpCas9	negative selection	7514731
161417809	161417832	2	+	27260156	MEWO	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.7676567514534618	[163]	[124,110,40]	-9	hSpCas9	negative selection	7578983
161418251	161418274	2	+	27260156	MEWO	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.26381646766058797	[445]	[634,460,432]	6	hSpCas9	negative selection	7578984
161417720	161417743	2	-	27260156	MEWO	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.2788326216146457	[203]	[161,118,191]	-6	hSpCas9	negative selection	7578985
161416794	161416817	2	-	27260156	LNCAPCLONEFGC	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.09223682733217142	[96]	[92,86,72,118]	1	hSpCas9	negative selection	7635980
161418202	161418225	2	+	27260156	LNCAPCLONEFGC	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.08482076831211655	[356]	[342,187,395,312]	-1	hSpCas9	negative selection	7635981
161416939	161416962	2	-	27260156	LNCAPCLONEFGC	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.3669126895087918	[538]	[591,593,883,488]	6	hSpCas9	negative selection	7635982
161417809	161417832	2	+	27260156	LNCAPCLONEFGC	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	0.13908110641906557	[163]	[200,127,197,133]	2	hSpCas9	negative selection	7700234
161418251	161418274	2	+	27260156	LNCAPCLONEFGC	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.6354806956209704	[445]	[894,475,540,589]	8	hSpCas9	negative selection	7700235
161417720	161417743	2	-	27260156	LNCAPCLONEFGC	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.3876762070455606	[203]	[164,127,219,63]	-6	hSpCas9	negative selection	7700236
161416794	161416817	2	-	27260156	PANC0327	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.2291450465868774	[96]	[105,80,124,94]	3	hSpCas9	negative selection	7757231
161418202	161418225	2	+	27260156	PANC0327	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.03168165846379245	[356]	[724,176,216,172]	0	hSpCas9	negative selection	7757232
161416939	161416962	2	-	27260156	PANC0327	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	-0.03912320927570537	[538]	[588,450,508,326]	0	hSpCas9	negative selection	7757233
161417809	161417832	2	+	27260156	PANC0327	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	0.1651754839366013	[163]	[249,103,102,210]	2	hSpCas9	negative selection	7821485
161418251	161418274	2	+	27260156	PANC0327	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.5659218487243458	[445]	[756,707,476,401]	8	hSpCas9	negative selection	7821486
161417720	161417743	2	-	27260156	PANC0327	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	0.8939869229448782	[203]	[227,293,162,657]	9	hSpCas9	negative selection	7821487
161416794	161416817	2	-	27260156	NCIH2009	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.366974105178556	[96]	[192,209,123]	5	hSpCas9	negative selection	7878482
161418202	161418225	2	+	27260156	NCIH2009	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.2149188037618442	[356]	[444,293,554]	-3	hSpCas9	negative selection	7878483
161416939	161416962	2	-	27260156	NCIH2009	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.5784806441327399	[538]	[1455,750,1236]	7	hSpCas9	negative selection	7878484
161417809	161417832	2	+	27260156	NCIH2009	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.4709398006212637	[163]	[295,82,143]	-6	hSpCas9	negative selection	7942736
161418251	161418274	2	+	27260156	NCIH2009	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.12548417828708913	[445]	[786,531,742]	1	hSpCas9	negative selection	7942737
161417720	161417743	2	-	27260156	NCIH2009	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.6758847147479157	[203]	[197,166,173]	-7	hSpCas9	negative selection	7942738
161416794	161416817	2	-	27260156	NCIH1373	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.10013233034655888	[96]	[90,22,70,61]	-1	hSpCas9	negative selection	7999733
161418202	161418225	2	+	27260156	NCIH1373	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.1297748063193071	[356]	[379,393,138,226]	1	hSpCas9	negative selection	7999734
161416939	161416962	2	-	27260156	NCIH1373	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.16563291577364325	[538]	[550,544,1139,115]	1	hSpCas9	negative selection	7999735
161417809	161417832	2	+	27260156	NCIH1373	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.4343140279637743	[163]	[213,153,144,8]	-4	hSpCas9	negative selection	8063987
161418251	161418274	2	+	27260156	NCIH1373	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.36114735014616667	[445]	[588,313,862,218]	3	hSpCas9	negative selection	8063988
161417720	161417743	2	-	27260156	NCIH1373	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	0.06775723922328081	[203]	[289,144,225,83]	0	hSpCas9	negative selection	8063989
161416794	161416817	2	-	27260156	PATU8902	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	1.065801118191848	[96]	[74,359,469,163]	9	hSpCas9	negative selection	8120984
161418202	161418225	2	+	27260156	PATU8902	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.31268301414130434	[356]	[402,663,284,259]	-3	hSpCas9	negative selection	8120985
161416939	161416962	2	-	27260156	PATU8902	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.2188521666222969	[538]	[1142,918,645,829]	2	hSpCas9	negative selection	8120986
161417809	161417832	2	+	27260156	PATU8902	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	0.2202747718380198	[163]	[43,615,205,208]	2	hSpCas9	negative selection	8185238
161418251	161418274	2	+	27260156	PATU8902	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.4778981418507664	[445]	[897,821,593,1255]	5	hSpCas9	negative selection	8185239
161417720	161417743	2	-	27260156	PATU8902	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	0.08010976035193718	[203]	[139,302,247,553]	0	hSpCas9	negative selection	8185240
161416794	161416817	2	-	27260156	PANC1	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.23481513134409937	[96]	[48,129,54,61]	-4	hSpCas9	negative selection	8242235
161418202	161418225	2	+	27260156	PANC1	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.11022957665093741	[356]	[428,231,312,322]	1	hSpCas9	negative selection	8242236
161416939	161416962	2	-	27260156	PANC1	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	-0.13263518823521936	[538]	[531,450,395,322]	-2	hSpCas9	negative selection	8242237
161417809	161417832	2	+	27260156	PANC1	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.3935016810665575	[163]	[124,158,72,83]	-6	hSpCas9	negative selection	8306489
161418251	161418274	2	+	27260156	PANC1	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.42518999979163746	[445]	[450,708,557,392]	7	hSpCas9	negative selection	8306490
161417720	161417743	2	-	27260156	PANC1	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	0.38721764061103736	[203]	[176,285,367,114]	6	hSpCas9	negative selection	8306491
161416794	161416817	2	-	27260156	PANC0813	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.33417889365168896	[96]	[125,154,135,154]	5	hSpCas9	negative selection	8363486
161418202	161418225	2	+	27260156	PANC0813	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.19424521413806578	[356]	[378,348,394,344]	-3	hSpCas9	negative selection	8363487
161416939	161416962	2	-	27260156	PANC0813	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.10720270107325308	[538]	[863,685,600,596]	1	hSpCas9	negative selection	8363488
161417809	161417832	2	+	27260156	PANC0813	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.08831223721746673	[163]	[190,92,245,194]	-1	hSpCas9	negative selection	8427740
161418251	161418274	2	+	27260156	PANC0813	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.1864948284164858	[445]	[491,443,801,634]	3	hSpCas9	negative selection	8427741
161417720	161417743	2	-	27260156	PANC0813	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.2332222541907394	[203]	[304,133,174,209]	-4	hSpCas9	negative selection	8427742
161416794	161416817	2	-	27260156	RDES	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.03939606279961083	[96]	[103,124,118,106]	0	hSpCas9	negative selection	8484737
161418202	161418225	2	+	27260156	RDES	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.25917080558767974	[356]	[215,255,483,467]	-4	hSpCas9	negative selection	8484738
161416939	161416962	2	-	27260156	RDES	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.06899543009246412	[538]	[576,702,619,695]	1	hSpCas9	negative selection	8484739
161417809	161417832	2	+	27260156	RDES	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.012870328837362832	[163]	[178,191,194,174]	0	hSpCas9	negative selection	8548991
161418251	161418274	2	+	27260156	RDES	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.4393569768670373	[445]	[522,601,647,1094]	7	hSpCas9	negative selection	8548992
161417720	161417743	2	-	27260156	RDES	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.16561851172173347	[203]	[161,246,196,233]	-3	hSpCas9	negative selection	8548993
161416794	161416817	2	-	27260156	PC3	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.5427504820048172	[96]	[44,37,131,80]	-8	hSpCas9	negative selection	8605988
161418202	161418225	2	+	27260156	PC3	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.29634920576172924	[356]	[119,377,518,279]	-6	hSpCas9	negative selection	8605989
161416939	161416962	2	-	27260156	PC3	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	-0.009894797389235127	[538]	[295,580,887,562]	0	hSpCas9	negative selection	8605990
161417809	161417832	2	+	27260156	PC3	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.15706500391191414	[163]	[46,130,223,255]	-4	hSpCas9	negative selection	8670242
161418251	161418274	2	+	27260156	PC3	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.01431486911062823	[445]	[252,391,866,498]	0	hSpCas9	negative selection	8670243
161417720	161417743	2	-	27260156	PC3	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.49137158964949434	[203]	[52,93,355,194]	-8	hSpCas9	negative selection	8670244
161416794	161416817	2	-	27260156	PATU8988T	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.1950682367244756	[96]	[158,102,83,80]	3	hSpCas9	negative selection	8727239
161418202	161418225	2	+	27260156	PATU8988T	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.2763264404427976	[356]	[145,385,263,358]	-5	hSpCas9	negative selection	8727240
161416939	161416962	2	-	27260156	PATU8988T	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.46593531489996537	[538]	[784,694,702,689]	7	hSpCas9	negative selection	8727241
161417809	161417832	2	+	27260156	PATU8988T	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	0.533210251212678	[163]	[178,144,350,232]	8	hSpCas9	negative selection	8791493
161418251	161418274	2	+	27260156	PATU8988T	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	-0.07543222349142328	[445]	[423,352,348,513]	-1	hSpCas9	negative selection	8791494
161417720	161417743	2	-	27260156	PATU8988T	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.3096882666630547	[203]	[252,95,90,193]	-5	hSpCas9	negative selection	8791495
161416794	161416817	2	-	27260156	T47D	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.10442225160854646	[96]	[128,110,120,125]	2	hSpCas9	negative selection	8848490
161418202	161418225	2	+	27260156	T47D	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.22963422497852976	[356]	[385,268,340,432]	-5	hSpCas9	negative selection	8848491
161416939	161416962	2	-	27260156	T47D	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.12222341500606543	[538]	[650,725,626,727]	2	hSpCas9	negative selection	8848492
161417809	161417832	2	+	27260156	T47D	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.3888032591472912	[163]	[186,132,146,116]	-7	hSpCas9	negative selection	8912744
161418251	161418274	2	+	27260156	T47D	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.13816950838633513	[445]	[565,536,560,627]	3	hSpCas9	negative selection	8912745
161417720	161417743	2	-	27260156	T47D	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.3735333231035134	[203]	[147,160,233,191]	-7	hSpCas9	negative selection	8912746
161416794	161416817	2	-	27260156	SU8686	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.22281131836399792	[96]	[63,98,70,96]	-4	hSpCas9	negative selection	8969741
161418202	161418225	2	+	27260156	SU8686	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.08452763972649058	[356]	[302,261,392,399]	-1	hSpCas9	negative selection	8969742
161416939	161416962	2	-	27260156	SU8686	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.04238300228334588	[538]	[499,622,484,589]	0	hSpCas9	negative selection	8969743
161417809	161417832	2	+	27260156	SU8686	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.8077249075520219	[163]	[78,61,74,172]	-8	hSpCas9	negative selection	9033995
161418251	161418274	2	+	27260156	SU8686	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	-0.046156113287184164	[445]	[434,319,420,569]	-1	hSpCas9	negative selection	9033996
161417720	161417743	2	-	27260156	SU8686	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	0.22527022689989462	[203]	[231,258,224,222]	4	hSpCas9	negative selection	9033997
161416794	161416817	2	-	27260156	SKES1	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.2398304433313756	[96]	[105,94,77,55]	-5	hSpCas9	negative selection	9090992
161418202	161418225	2	+	27260156	SKES1	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.3713114891594102	[356]	[281,272,257,284]	-7	hSpCas9	negative selection	9090993
161416939	161416962	2	-	27260156	SKES1	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	-0.07668579861501977	[538]	[608,557,479,417]	-2	hSpCas9	negative selection	9090994
161417809	161417832	2	+	27260156	SKES1	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.42411451606835526	[163]	[73,210,104,102]	-7	hSpCas9	negative selection	9155246
161418251	161418274	2	+	27260156	SKES1	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.13398485897121787	[445]	[419,543,442,532]	3	hSpCas9	negative selection	9155247
161417720	161417743	2	-	27260156	SKES1	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.520020541010138	[203]	[161,137,119,147]	-8	hSpCas9	negative selection	9155248
161416794	161416817	2	-	27260156	TOV112D	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	-0.19214357347123112	[96]	[62,23,73,159]	-4	hSpCas9	negative selection	9212243
161418202	161418225	2	+	27260156	TOV112D	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.07731351729139085	[356]	[431,228,414,261]	-1	hSpCas9	negative selection	9212244
161416939	161416962	2	-	27260156	TOV112D	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	-0.3892272829011212	[538]	[388,491,562,226]	-6	hSpCas9	negative selection	9212245
161417809	161417832	2	+	27260156	TOV112D	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.09636837978791268	[163]	[251,141,81,143]	-2	hSpCas9	negative selection	9276497
161418251	161418274	2	+	27260156	TOV112D	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.7443371307884439	[445]	[756,783,839,623]	9	hSpCas9	negative selection	9276498
161417720	161417743	2	-	27260156	TOV112D	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.48432434744300434	[203]	[103,182,173,128]	-7	hSpCas9	negative selection	9276499
161416794	161416817	2	-	27260156	TC71	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.0822967455414867	[96]	[87,113,179,52]	2	hSpCas9	negative selection	9333494
161418202	161418225	2	+	27260156	TC71	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	-0.32371090465310676	[356]	[244,374,324,276]	-7	hSpCas9	negative selection	9333495
161416939	161416962	2	-	27260156	TC71	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	-0.031722981678649675	[538]	[406,650,607,598]	-1	hSpCas9	negative selection	9333496
161417809	161417832	2	+	27260156	TC71	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.31284394213937494	[163]	[139,102,158,164]	-7	hSpCas9	negative selection	9397748
161418251	161418274	2	+	27260156	TC71	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.12534382383536768	[445]	[541,527,447,572]	3	hSpCas9	negative selection	9397749
161417720	161417743	2	-	27260156	TC71	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.4906805280787019	[203]	[116,179,188,134]	-8	hSpCas9	negative selection	9397750
161416794	161416817	2	-	27260156	TC32	viability	CGGGGTGCGCCGGTCCGTGCTGG	TBR1	ENSG00000136535	0.3880018339434339	[96]	[114,86,156,130]	6	hSpCas9	negative selection	9454745
161418202	161418225	2	+	27260156	TC32	viability	AAATCGGGTCTATATGCATCCGG	TBR1	ENSG00000136535	0.2495310382060339	[356]	[204,384,636,416]	4	hSpCas9	negative selection	9454746
161416939	161416962	2	-	27260156	TC32	viability	TAGGAGTGGCCGTACTGCTGTGG	TBR1	ENSG00000136535	0.12163528776942206	[538]	[474,269,693,896]	2	hSpCas9	negative selection	9454747
161417809	161417832	2	+	27260156	TC32	viability	AAAGCGGACACCAATGTGCAAGG	TBR1	ENSG00000136535	-0.4803758791943975	[163]	[65,79,164,153]	-7	hSpCas9	negative selection	9518999
161418251	161418274	2	+	27260156	TC32	viability	ATGCGCCAAGAAATCTCTTTTGG	TBR1	ENSG00000136535	0.28850562390090523	[445]	[477,472,549,540]	5	hSpCas9	negative selection	9519000
161417720	161417743	2	-	27260156	TC32	viability	AAAAATATTGTAATGAGCCGTGG	TBR1	ENSG00000136535	-0.5963654781503414	[203]	[131,74,115,197]	-8	hSpCas9	negative selection	9519001
161416527	161416550	2	+	27869803	HPAFII	viability after 27 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.40450634028759347	[167]	[159,80,NaN]	3	hSpCas9	negative selection	9572055
161417044	161417067	2	-	27869803	HPAFII	viability after 27 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.8967344874229439	[519]	[706,343,NaN]	7	hSpCas9	negative selection	9572056
161417793	161417816	2	+	27869803	HPAFII	viability after 27 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.6175104361521637	[368]	[379,228,NaN]	5	hSpCas9	negative selection	9572057
161417800	161417823	2	-	27869803	HPAFII	viability after 27 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.8277855597225035	[252]	[366,126,NaN]	6	hSpCas9	negative selection	9572058
161418984	161419007	2	-	27869803	HPAFII	viability after 27 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	-1.123553811219757	[294]	[80,62,NaN]	-6	hSpCas9	negative selection	9572059
161423826	161423849	2	-	27869803	HPAFII	viability after 27 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.5681472934845839	[160]	[49,62,NaN]	-4	hSpCas9	negative selection	9572060
161416527	161416550	2	+	27869803	HPAFII	viability after 15 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.7541741191424539	[167]	[499,182,NaN]	8	hSpCas9	negative selection	9654504
161417044	161417067	2	-	27869803	HPAFII	viability after 15 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.6980488538650764	[519]	[1357,625,NaN]	7	hSpCas9	negative selection	9654505
161417793	161417816	2	+	27869803	HPAFII	viability after 15 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.25646358755572973	[368]	[765,291,NaN]	3	hSpCas9	negative selection	9654506
161417800	161417823	2	-	27869803	HPAFII	viability after 15 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.9309274979381255	[252]	[941,254,NaN]	8	hSpCas9	negative selection	9654507
161418984	161419007	2	-	27869803	HPAFII	viability after 15 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.5075279793138467	[294]	[438,457,NaN]	6	hSpCas9	negative selection	9654508
161423826	161423849	2	-	27869803	HPAFII	viability after 15 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.3201003584149823	[160]	[145,133,NaN]	-4	hSpCas9	negative selection	9654509
161416527	161416550	2	+	27869803	ASPC1	viability after 36 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.12184589583269165	[724]	[471,168,218]	1	hSpCas9	negative selection	9736953
161417044	161417067	2	-	27869803	ASPC1	viability after 36 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.9543616008437936	[1545]	[1760,668,831]	8	hSpCas9	negative selection	9736954
161417793	161417816	2	+	27869803	ASPC1	viability after 36 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.8645969679267522	[874]	[290,645,664]	8	hSpCas9	negative selection	9736955
161417800	161417823	2	-	27869803	ASPC1	viability after 36 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	-0.16492648252781122	[619]	[203,132,230]	-2	hSpCas9	negative selection	9736956
161418984	161419007	2	-	27869803	ASPC1	viability after 36 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	0.42259442114682233	[925]	[636,243,435]	4	hSpCas9	negative selection	9736957
161423826	161423849	2	-	27869803	ASPC1	viability after 36 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	0.5402699139295569	[371]	[270,173,140]	5	hSpCas9	negative selection	9736958
161416527	161416550	2	+	27869803	PATU8988S	viability after 35 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.2845259257790716	[370]	[179,183,NaN]	3	hSpCas9	negative selection	9819402
161417044	161417067	2	-	27869803	PATU8988S	viability after 35 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.6489672621255711	[1206]	[655,868,NaN]	7	hSpCas9	negative selection	9819403
161417793	161417816	2	+	27869803	PATU8988S	viability after 35 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.6525828549616189	[624]	[481,308,NaN]	7	hSpCas9	negative selection	9819404
161417800	161417823	2	-	27869803	PATU8988S	viability after 35 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.919073282757549	[522]	[308,487,NaN]	8	hSpCas9	negative selection	9819405
161418984	161419007	2	-	27869803	PATU8988S	viability after 35 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	-0.5302780165955554	[754]	[231,188,NaN]	-5	hSpCas9	negative selection	9819406
161423826	161423849	2	-	27869803	PATU8988S	viability after 35 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	0.5241462883147029	[295]	[144,197,NaN]	6	hSpCas9	negative selection	9819407
161416527	161416550	2	+	27869803	PATU8988S	viability after 31 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.10403361962321167	[370]	[136,186,NaN]	1	hSpCas9	negative selection	9901851
161417044	161417067	2	-	27869803	PATU8988S	viability after 31 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.6795811854491749	[1206]	[670,897,NaN]	7	hSpCas9	negative selection	9901852
161417793	161417816	2	+	27869803	PATU8988S	viability after 31 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.8559850397747023	[624]	[436,468,NaN]	8	hSpCas9	negative selection	9901853
161417800	161417823	2	-	27869803	PATU8988S	viability after 31 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.5523537661136413	[522]	[223,409,NaN]	6	hSpCas9	negative selection	9901854
161418984	161419007	2	-	27869803	PATU8988S	viability after 31 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	-0.36555750947297017	[754]	[168,315,NaN]	-4	hSpCas9	negative selection	9901855
161423826	161423849	2	-	27869803	PATU8988S	viability after 31 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	0.549995951094167	[295]	[185,155,NaN]	6	hSpCas9	negative selection	9901856
161416527	161416550	2	+	27869803	HPAFII	viability after 35 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	1.0089569123390483	[167]	[252,78,NaN]	6	hSpCas9	negative selection	9984300
161417044	161417067	2	-	27869803	HPAFII	viability after 35 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.8870068342666169	[519]	[626,328,NaN]	6	hSpCas9	negative selection	9984301
161417793	161417816	2	+	27869803	HPAFII	viability after 35 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.6531196768604584	[368]	[289,297,NaN]	4	hSpCas9	negative selection	9984302
161417800	161417823	2	-	27869803	HPAFII	viability after 35 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	1.1167432123123362	[252]	[368,174,NaN]	7	hSpCas9	negative selection	9984303
161418984	161419007	2	-	27869803	HPAFII	viability after 35 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	-0.3936499482432715	[294]	[60,172,NaN]	-2	hSpCas9	negative selection	9984304
161423826	161423849	2	-	27869803	HPAFII	viability after 35 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.36072746177610193	[160]	[70,54,NaN]	-2	hSpCas9	negative selection	9984305
161416527	161416550	2	+	27869803	HPAFII	viability after 31 days	TATCTCGACCACTGACAACCTGG	TBR1	ENSG00000136535	0.5973174722828661	[167]	[223,53,NaN]	4	hSpCas9	negative selection	10066749
161417044	161417067	2	-	27869803	HPAFII	viability after 31 days	CGGTGAAATTTCAGCCAAAGGGG	TBR1	ENSG00000136535	0.9312597813264885	[519]	[712,385,NaN]	7	hSpCas9	negative selection	10066750
161417793	161417816	2	+	27869803	HPAFII	viability after 31 days	ATGGGTTCCTTGCGGCAAAGCGG	TBR1	ENSG00000136535	0.6688086252475682	[368]	[389,262,NaN]	5	hSpCas9	negative selection	10066751
161417800	161417823	2	-	27869803	HPAFII	viability after 31 days	TTGGTGTCCGCTTTGCCGCAAGG	TBR1	ENSG00000136535	0.5782008596215458	[252]	[300,114,NaN]	4	hSpCas9	negative selection	10066752
161418984	161419007	2	-	27869803	HPAFII	viability after 31 days	GGAAAGTGAACGTCTGCACGCGG	TBR1	ENSG00000136535	-0.6324321077737545	[294]	[79,135,NaN]	-4	hSpCas9	negative selection	10066753
161423826	161423849	2	-	27869803	HPAFII	viability after 31 days	TTGGTGCCGCAGTACTGCGGGGG	TBR1	ENSG00000136535	-0.3746067824459647	[160]	[73,64,NaN]	-3	hSpCas9	negative selection	10066754
161416760	161416783	2	-	28162770	P31FUJ	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-0.9143828953041551	[246]	[153]	-6	hSpCas9	negative selection	10248018
161416747	161416770	2	-	28162770	P31FUJ	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	0.157598015370091	[250]	[328]	1	hSpCas9	negative selection	10248019
161416814	161416837	2	-	28162770	P31FUJ	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	0.3735339470993446	[66]	[101]	4	hSpCas9	negative selection	10248020
161416887	161416910	2	-	28162770	P31FUJ	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	0.3816470608071585	[112]	[172]	4	hSpCas9	negative selection	10248021
161417004	161417027	2	+	28162770	P31FUJ	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.41845197501596043	[318]	[500]	4	hSpCas9	negative selection	10248022
161417081	161417104	2	+	28162770	P31FUJ	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	-0.3550579544653768	[159]	[146]	-3	hSpCas9	negative selection	10248023
161417756	161417779	2	+	28162770	P31FUJ	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	0.058537570639560665	[142]	[174]	0	hSpCas9	negative selection	10248024
161418921	161418944	2	+	28162770	P31FUJ	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	0.31973881861440034	[44]	[65]	3	hSpCas9	negative selection	10248025
161418942	161418965	2	+	28162770	P31FUJ	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	0.5175839055141492	[106]	[179]	6	hSpCas9	negative selection	10248026
161416617	161416640	2	+	28162770	P31FUJ	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	-0.09967712117501792	[299]	[328]	-1	hSpCas9	negative selection	10248027
161416760	161416783	2	-	28162770	TF1	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10417384
161416747	161416770	2	-	28162770	TF1	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	NaN	[NaN]	[258]	1	hSpCas9	negative selection	10417385
161416814	161416837	2	-	28162770	TF1	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10417386
161416887	161416910	2	-	28162770	TF1	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10417387
161417004	161417027	2	+	28162770	TF1	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	NaN	[NaN]	[267]	1	hSpCas9	negative selection	10417388
161417081	161417104	2	+	28162770	TF1	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	NaN	[NaN]	[395]	1	hSpCas9	negative selection	10417389
161417756	161417779	2	+	28162770	TF1	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	NaN	[NaN]	[51]	1	hSpCas9	negative selection	10417390
161418921	161418944	2	+	28162770	TF1	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10417391
161418942	161418965	2	+	28162770	TF1	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10417392
161416617	161416640	2	+	28162770	TF1	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10417393
161416760	161416783	2	-	28162770	SKM1	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	0.26546114322833375	[71]	[152]	2	hSpCas9	negative selection	10586750
161416747	161416770	2	-	28162770	SKM1	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	0.5359547060495709	[86]	[222]	5	hSpCas9	negative selection	10586751
161416814	161416837	2	-	28162770	SKM1	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	1.2035333940851323	[13]	[56]	9	hSpCas9	negative selection	10586752
161416887	161416910	2	-	28162770	SKM1	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	-0.31950135749282205	[23]	[33]	-3	hSpCas9	negative selection	10586753
161417004	161417027	2	+	28162770	SKM1	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.06696698958925063	[80]	[149]	0	hSpCas9	negative selection	10586754
161417081	161417104	2	+	28162770	SKM1	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	0.45810622117072974	[55]	[135]	4	hSpCas9	negative selection	10586755
161417756	161417779	2	+	28162770	SKM1	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	0.347923303420307	[31]	[71]	3	hSpCas9	negative selection	10586756
161418921	161418944	2	+	28162770	SKM1	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	0.9017885073964674	[32]	[108]	8	hSpCas9	negative selection	10586757
161418942	161418965	2	+	28162770	SKM1	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	0.819544331065518	[24]	[77]	7	hSpCas9	negative selection	10586758
161416617	161416640	2	+	28162770	SKM1	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	0.4003907233144425	[59]	[139]	4	hSpCas9	negative selection	10586759
161416760	161416783	2	-	28162770	SKM1	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	0.26546114322833375	[71]	[152]	2	hSpCas9	negative selection	10756116
161416747	161416770	2	-	28162770	SKM1	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	0.5359547060495709	[86]	[222]	5	hSpCas9	negative selection	10756117
161416814	161416837	2	-	28162770	SKM1	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	1.2035333940851323	[13]	[56]	9	hSpCas9	negative selection	10756118
161416887	161416910	2	-	28162770	SKM1	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	-0.31950135749282205	[23]	[33]	-3	hSpCas9	negative selection	10756119
161417004	161417027	2	+	28162770	SKM1	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.06696698958925063	[80]	[149]	0	hSpCas9	negative selection	10756120
161417081	161417104	2	+	28162770	SKM1	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	0.45810622117072974	[55]	[135]	4	hSpCas9	negative selection	10756121
161417756	161417779	2	+	28162770	SKM1	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	0.347923303420307	[31]	[71]	3	hSpCas9	negative selection	10756122
161418921	161418944	2	+	28162770	SKM1	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	0.9017885073964674	[32]	[108]	8	hSpCas9	negative selection	10756123
161418942	161418965	2	+	28162770	SKM1	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	0.819544331065518	[24]	[77]	7	hSpCas9	negative selection	10756124
161416617	161416640	2	+	28162770	SKM1	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	0.4003907233144425	[59]	[139]	4	hSpCas9	negative selection	10756125
161416760	161416783	2	-	28162770	PL21	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-0.5899373161364484	[248]	[71]	-4	hSpCas9	negative selection	10925482
161416747	161416770	2	-	28162770	PL21	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	-0.8442545048691334	[230]	[55]	-5	hSpCas9	negative selection	10925483
161416814	161416837	2	-	28162770	PL21	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	0.23861376230395592	[73]	[37]	2	hSpCas9	negative selection	10925484
161416887	161416910	2	-	28162770	PL21	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	-0.5527675235459075	[90]	[26]	-4	hSpCas9	negative selection	10925485
161417004	161417027	2	+	28162770	PL21	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.5786512377430499	[299]	[194]	5	hSpCas9	negative selection	10925486
161417081	161417104	2	+	28162770	PL21	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	0.1622714288988771	[192]	[93]	1	hSpCas9	negative selection	10925487
161417756	161417779	2	+	28162770	PL21	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	-1.2328197927867859	[80]	[14]	-7	hSpCas9	negative selection	10925488
161418921	161418944	2	+	28162770	PL21	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	0.06263609073938525	[10]	[4]	0	hSpCas9	negative selection	10925489
161418942	161418965	2	+	28162770	PL21	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	-2.1217884803980422	[99]	[9]	-8	hSpCas9	negative selection	10925490
161416617	161416640	2	+	28162770	PL21	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	-0.7008503796795141	[182]	[48]	-5	hSpCas9	negative selection	10925491
161416760	161416783	2	-	28162770	P31FUJ	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-0.9143828953041551	[246]	[153]	-6	hSpCas9	negative selection	11094848
161416747	161416770	2	-	28162770	P31FUJ	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	0.157598015370091	[250]	[328]	1	hSpCas9	negative selection	11094849
161416814	161416837	2	-	28162770	P31FUJ	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	0.3735339470993446	[66]	[101]	4	hSpCas9	negative selection	11094850
161416887	161416910	2	-	28162770	P31FUJ	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	0.3816470608071585	[112]	[172]	4	hSpCas9	negative selection	11094851
161417004	161417027	2	+	28162770	P31FUJ	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.41845197501596043	[318]	[500]	4	hSpCas9	negative selection	11094852
161417081	161417104	2	+	28162770	P31FUJ	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	-0.3550579544653768	[159]	[146]	-3	hSpCas9	negative selection	11094853
161417756	161417779	2	+	28162770	P31FUJ	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	0.058537570639560665	[142]	[174]	0	hSpCas9	negative selection	11094854
161418921	161418944	2	+	28162770	P31FUJ	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	0.31973881861440034	[44]	[65]	3	hSpCas9	negative selection	11094855
161418942	161418965	2	+	28162770	P31FUJ	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	0.5175839055141492	[106]	[179]	6	hSpCas9	negative selection	11094856
161416617	161416640	2	+	28162770	P31FUJ	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	-0.09967712117501792	[299]	[328]	-1	hSpCas9	negative selection	11094857
161416760	161416783	2	-	28162770	OCIAML5	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-0.9092104779676058	[102]	[98]	-5	hSpCas9	negative selection	11264214
161416747	161416770	2	-	28162770	OCIAML5	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	-0.5055088094679195	[150]	[191]	-3	hSpCas9	negative selection	11264215
161416814	161416837	2	-	28162770	OCIAML5	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	-0.9422643798355752	[65]	[61]	-5	hSpCas9	negative selection	11264216
161416887	161416910	2	-	28162770	OCIAML5	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	-0.5576192123987418	[52]	[64]	-4	hSpCas9	negative selection	11264217
161417004	161417027	2	+	28162770	OCIAML5	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	-0.8771575518268275	[173]	[170]	-5	hSpCas9	negative selection	11264218
161417081	161417104	2	+	28162770	OCIAML5	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	1.0037498401502523	[91]	[332]	8	hSpCas9	negative selection	11264219
161417756	161417779	2	+	28162770	OCIAML5	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	0.4553619543282503	[79]	[197]	4	hSpCas9	negative selection	11264220
161418921	161418944	2	+	28162770	OCIAML5	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	-0.4143803326399529	[78]	[106]	-3	hSpCas9	negative selection	11264221
161418942	161418965	2	+	28162770	OCIAML5	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	-0.4207272592560527	[65]	[88]	-3	hSpCas9	negative selection	11264222
161416617	161416640	2	+	28162770	OCIAML5	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	0.019078363459578973	[157]	[288]	0	hSpCas9	negative selection	11264223
161416760	161416783	2	-	28162770	EOL1	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-0.45518959095904343	[470]	[180]	-3	hSpCas9	negative selection	11433580
161416747	161416770	2	-	28162770	EOL1	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	0.441173142528537	[280]	[200]	4	hSpCas9	negative selection	11433581
161416814	161416837	2	-	28162770	EOL1	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	-0.20320777562783832	[117]	[53]	-1	hSpCas9	negative selection	11433582
161416887	161416910	2	-	28162770	EOL1	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	-1.2738657868314736	[178]	[38]	-7	hSpCas9	negative selection	11433583
161417004	161417027	2	+	28162770	EOL1	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.36343201280374626	[629]	[426]	3	hSpCas9	negative selection	11433584
161417081	161417104	2	+	28162770	EOL1	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	-0.3010119288445965	[303]	[129]	-2	hSpCas9	negative selection	11433585
161417756	161417779	2	+	28162770	EOL1	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	-0.7128821490447572	[139]	[44]	-5	hSpCas9	negative selection	11433586
161418921	161418944	2	+	28162770	EOL1	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	-1.075452228429465	[19]	[4]	-6	hSpCas9	negative selection	11433587
161418942	161418965	2	+	28162770	EOL1	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	-0.09359957513972483	[159]	[78]	0	hSpCas9	negative selection	11433588
161416617	161416640	2	+	28162770	EOL1	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	-1.3245474433053852	[308]	[64]	-7	hSpCas9	negative selection	11433589
161416760	161416783	2	-	28162770	MOLM13	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-1.0461647428748715	[396]	[138]	-5	hSpCas9	negative selection	11602946
161416747	161416770	2	-	28162770	MOLM13	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	-0.316381927399984	[340]	[197]	-2	hSpCas9	negative selection	11602947
161416814	161416837	2	-	28162770	MOLM13	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	1.6948043615717205	[90]	[212]	9	hSpCas9	negative selection	11602948
161416887	161416910	2	-	28162770	MOLM13	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	1.2291025219574623	[117]	[199]	8	hSpCas9	negative selection	11602949
161417004	161417027	2	+	28162770	MOLM13	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.492394345053227	[466]	[474]	3	hSpCas9	negative selection	11602950
161417081	161417104	2	+	28162770	MOLM13	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	0.650894210030881	[243]	[276]	5	hSpCas9	negative selection	11602951
161417756	161417779	2	+	28162770	MOLM13	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	-2.1311483043883	[102]	[16]	-7	hSpCas9	negative selection	11602952
161418921	161418944	2	+	28162770	MOLM13	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	-0.039070607175304306	[161]	[113]	0	hSpCas9	negative selection	11602953
161418942	161418965	2	+	28162770	MOLM13	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	-0.2627207175818038	[150]	[90]	-2	hSpCas9	negative selection	11602954
161416617	161416640	2	+	28162770	MOLM13	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	-1.3693154682595856	[292]	[81]	-6	hSpCas9	negative selection	11602955
161416760	161416783	2	-	28162770	HEL	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-0.3885121019840826	[279]	[136]	-3	hSpCas9	negative selection	11772312
161416747	161416770	2	-	28162770	HEL	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	-0.964317439571416	[328]	[107]	-5	hSpCas9	negative selection	11772313
161416814	161416837	2	-	28162770	HEL	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	-0.30067763963327554	[99]	[51]	-2	hSpCas9	negative selection	11772314
161416887	161416910	2	-	28162770	HEL	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	0.8998966714974815	[122]	[146]	7	hSpCas9	negative selection	11772315
161417004	161417027	2	+	28162770	HEL	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.8475586238888552	[412]	[475]	7	hSpCas9	negative selection	11772316
161417081	161417104	2	+	28162770	HEL	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	0.23131258627389215	[265]	[199]	2	hSpCas9	negative selection	11772317
161417756	161417779	2	+	28162770	HEL	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	1.0850492614293046	[130]	[177]	8	hSpCas9	negative selection	11772318
161418921	161418944	2	+	28162770	HEL	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	0.5118913525407353	[172]	[157]	4	hSpCas9	negative selection	11772319
161418942	161418965	2	+	28162770	HEL	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	0.0006324241755919502	[102]	[65]	0	hSpCas9	negative selection	11772320
161416617	161416640	2	+	28162770	HEL	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	0.36302568501993276	[260]	[214]	3	hSpCas9	negative selection	11772321
161416760	161416783	2	-	28162770	MV411	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-1.1061994038319252	[275]	[107]	-6	hSpCas9	negative selection	11941678
161416747	161416770	2	-	28162770	MV411	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	-0.20775707496805118	[169]	[123]	-1	hSpCas9	negative selection	11941679
161416814	161416837	2	-	28162770	MV411	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	-0.5756846871331454	[68]	[38]	-4	hSpCas9	negative selection	11941680
161416887	161416910	2	-	28162770	MV411	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	1.0317088597273378	[53]	[92]	8	hSpCas9	negative selection	11941681
161417004	161417027	2	+	28162770	MV411	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.8902312426273928	[325]	[508]	7	hSpCas9	negative selection	11941682
161417081	161417104	2	+	28162770	MV411	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	-0.12179625888294361	[216]	[167]	-1	hSpCas9	negative selection	11941683
161417756	161417779	2	+	28162770	MV411	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	-0.8091459775835921	[103]	[49]	-5	hSpCas9	negative selection	11941684
161418921	161418944	2	+	28162770	MV411	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	-0.30895579774160975	[24]	[16]	-2	hSpCas9	negative selection	11941685
161418942	161418965	2	+	28162770	MV411	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	0.8595118971211728	[122]	[187]	7	hSpCas9	negative selection	11941686
161416617	161416640	2	+	28162770	MV411	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	0.7376218267518316	[172]	[242]	6	hSpCas9	negative selection	11941687
161416760	161416783	2	-	28162770	MONOMAC1	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-0.14550654641947158	[164]	[170]	-1	hSpCas9	negative selection	12111044
161416747	161416770	2	-	28162770	MONOMAC1	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	0.22922790764254442	[159]	[214]	2	hSpCas9	negative selection	12111045
161416814	161416837	2	-	28162770	MONOMAC1	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	-1.6564684656968511	[43]	[15]	-8	hSpCas9	negative selection	12111046
161416887	161416910	2	-	28162770	MONOMAC1	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	-0.7550323001804407	[52]	[35]	-6	hSpCas9	negative selection	12111047
161417004	161417027	2	+	28162770	MONOMAC1	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.31892956107007087	[206]	[295]	3	hSpCas9	negative selection	12111048
161417081	161417104	2	+	28162770	MONOMAC1	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	0.6083157220869027	[102]	[179]	6	hSpCas9	negative selection	12111049
161417756	161417779	2	+	28162770	MONOMAC1	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	-1.4398933709557173	[70]	[29]	-8	hSpCas9	negative selection	12111050
161418921	161418944	2	+	28162770	MONOMAC1	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	-0.6120743463383973	[11]	[8]	-5	hSpCas9	negative selection	12111051
161418942	161418965	2	+	28162770	MONOMAC1	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	0.8878520505269593	[65]	[139]	7	hSpCas9	negative selection	12111052
161416617	161416640	2	+	28162770	MONOMAC1	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	-0.05330136959810422	[104]	[115]	0	hSpCas9	negative selection	12111053
161416760	161416783	2	-	28162770	OCIAML2	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	-0.9186446469672778	[58]	[172]	-6	hSpCas9	negative selection	12280410
161416747	161416770	2	-	28162770	OCIAML2	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	-0.4035156293836242	[41]	[175]	-3	hSpCas9	negative selection	12280411
161416814	161416837	2	-	28162770	OCIAML2	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	0.9293007816464742	[8]	[94]	8	hSpCas9	negative selection	12280412
161416887	161416910	2	-	28162770	OCIAML2	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	-0.07373967267357662	[14]	[78]	0	hSpCas9	negative selection	12280413
161417004	161417027	2	+	28162770	OCIAML2	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	0.35568325451932725	[53]	[382]	3	hSpCas9	negative selection	12280414
161417081	161417104	2	+	28162770	OCIAML2	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	-0.1234644388557759	[33]	[172]	-1	hSpCas9	negative selection	12280415
161417756	161417779	2	+	28162770	OCIAML2	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	0.21009165828442578	[16]	[108]	2	hSpCas9	negative selection	12280416
161418921	161418944	2	+	28162770	OCIAML2	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	-0.4331551198234983	[18]	[77]	-3	hSpCas9	negative selection	12280417
161418942	161418965	2	+	28162770	OCIAML2	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	0.7169971779336102	[17]	[163]	7	hSpCas9	negative selection	12280418
161416617	161416640	2	+	28162770	OCIAML2	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	1.075162078198317	[27]	[326]	8	hSpCas9	negative selection	12280419
161416760	161416783	2	-	28162770	OCIAML3	viability	GAACATGGCACTGGGAGCAGTGG	TBR1	ENSG00000136535	0.3273825249794705	[65]	[249]	3	hSpCas9	negative selection	12449776
161416747	161416770	2	-	28162770	OCIAML3	viability	GGAGCAGTGGCCGCAGACTGTGG	TBR1	ENSG00000136535	0.40059910090561834	[66]	[266]	4	hSpCas9	negative selection	12449777
161416814	161416837	2	-	28162770	OCIAML3	viability	AGGGCTGCCGATGGAGAAGGCGG	TBR1	ENSG00000136535	-0.4870924364076512	[25]	[55]	-4	hSpCas9	negative selection	12449778
161416887	161416910	2	-	28162770	OCIAML3	viability	GCGGCGAGGAGTTGGACAGGAGG	TBR1	ENSG00000136535	0.4315274517829745	[27]	[113]	4	hSpCas9	negative selection	12449779
161417004	161417027	2	+	28162770	OCIAML3	viability	GCTGGTGCCCGGCAAAGCACAGG	TBR1	ENSG00000136535	-0.1896173852448279	[84]	[224]	-1	hSpCas9	negative selection	12449780
161417081	161417104	2	+	28162770	OCIAML3	viability	TGATCATCACCAAACAGGGAAGG	TBR1	ENSG00000136535	0.462823582272513	[55]	[232]	4	hSpCas9	negative selection	12449781
161417756	161417779	2	+	28162770	OCIAML3	viability	TGGCGGATCCCAATCACTGGAGG	TBR1	ENSG00000136535	0.02412172433219223	[42]	[131]	0	hSpCas9	negative selection	12449782
161418921	161418944	2	+	28162770	OCIAML3	viability	CCAGCCCCGCCTGCATGTGGTGG	TBR1	ENSG00000136535	0.21957923544495556	[32]	[115]	2	hSpCas9	negative selection	12449783
161418942	161418965	2	+	28162770	OCIAML3	viability	GGAAGTGAACGAGGACGGCACGG	TBR1	ENSG00000136535	-0.2720795454368007	[27]	[69]	-2	hSpCas9	negative selection	12449784
161416617	161416640	2	+	28162770	OCIAML3	viability	TGACTCCAAGGACTCACCAGGGG	TBR1	ENSG00000136535	-0.36723677847714103	[46]	[109]	-3	hSpCas9	negative selection	12449785