Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:9496
• Symbol:TBX4
• Description:T-box transcription factor 4

DataSource: http://genomecrispr.dkfz.de/#!/results/TBX4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
61456505	61456528	17	+	26472758	Jiyoye	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	0.48117596294965015	[37]	[39]	3	hSpCas9	negative selection	162699
61467585	61467608	17	-	26472758	Jiyoye	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	-0.43773554517533375	[466]	[259]	-3	hSpCas9	negative selection	162700
61457536	61457559	17	+	26472758	Jiyoye	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.5972782648858161	[70]	[80]	4	hSpCas9	negative selection	162701
61457575	61457598	17	+	26472758	Jiyoye	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	0.7124674748013741	[156]	[193]	5	hSpCas9	negative selection	162702
61465909	61465932	17	-	26472758	Jiyoye	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.9280075448073137	[160]	[230]	6	hSpCas9	negative selection	162703
61467621	61467644	17	+	26472758	Jiyoye	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	1.1061731254730591	[76]	[124]	7	hSpCas9	negative selection	162704
61478742	61478765	17	-	26472758	Jiyoye	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-0.54391501801318	[28]	[14]	-4	hSpCas9	negative selection	162705
61480260	61480283	17	+	26472758	Jiyoye	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.6145003547533794	[329]	[380]	4	hSpCas9	negative selection	162706
61456663	61456686	17	-	26472758	Jiyoye	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	1.5915999526433007	[32]	[74]	8	hSpCas9	negative selection	162707
61457606	61457629	17	+	26472758	Jiyoye	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	5.107615099646965	[0]	[25]	9	hSpCas9	negative selection	162708
61456505	61456528	17	+	26472758	KBM7	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	0.15493902932178083	[318,222]	[177,105]	1	hSpCas9	negative selection	353817
61467585	61467608	17	-	26472758	KBM7	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	0.4493932306221391	[1268,1150]	[771,780]	5	hSpCas9	negative selection	353818
61457536	61457559	17	+	26472758	KBM7	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.16221801930039154	[600,654]	[399,273]	1	hSpCas9	negative selection	353819
61457575	61457598	17	+	26472758	KBM7	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.7582945095294281	[676,439]	[168,137]	-6	hSpCas9	negative selection	353820
61465909	61465932	17	-	26472758	KBM7	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.6429915643838527	[836,696]	[576,545]	7	hSpCas9	negative selection	353821
61467621	61467644	17	+	26472758	KBM7	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.6880491302719955	[401,292]	[367,163]	7	hSpCas9	negative selection	353822
61478742	61478765	17	-	26472758	KBM7	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-2.82892920293444	[337,312]	[10,30]	-9	hSpCas9	negative selection	353823
61480260	61480283	17	+	26472758	KBM7	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.7271838894230469	[1739,1499]	[1247,1265]	7	hSpCas9	negative selection	353824
61456663	61456686	17	-	26472758	KBM7	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.6777456281730989	[241,211]	[190,151]	7	hSpCas9	negative selection	353825
61457606	61457629	17	+	26472758	KBM7	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	0.5940234930666948	[179,179]	[177,83]	6	hSpCas9	negative selection	353826
61456505	61456528	17	+	26472758	Raji	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	0.6760442237656551	[88]	[32]	6	hSpCas9	negative selection	544935
61467585	61467608	17	-	26472758	Raji	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	0.01768914682467737	[646]	[151]	0	hSpCas9	negative selection	544936
61457536	61457559	17	+	26472758	Raji	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	1.0476772892493318	[147]	[70]	8	hSpCas9	negative selection	544937
61457575	61457598	17	+	26472758	Raji	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	0.6143435240934825	[227]	[80]	6	hSpCas9	negative selection	544938
61465909	61465932	17	-	26472758	Raji	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.4017672955650943	[348]	[106]	4	hSpCas9	negative selection	544939
61467621	61467644	17	+	26472758	Raji	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.014937286609004397	[144]	[33]	0	hSpCas9	negative selection	544940
61478742	61478765	17	-	26472758	Raji	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-3.232466467511025	[161]	[3]	-9	hSpCas9	negative selection	544941
61480260	61480283	17	+	26472758	Raji	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.2755062941819266	[800]	[224]	2	hSpCas9	negative selection	544942
61456663	61456686	17	-	26472758	Raji	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.5822924906298419	[117]	[40]	5	hSpCas9	negative selection	544943
61457606	61457629	17	+	26472758	Raji	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	-0.05659219973752638	[120]	[26]	0	hSpCas9	negative selection	544944
61456505	61456528	17	+	26472758	K562	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	1.4697110395086894	[141]	[331]	9	hSpCas9	negative selection	736053
61467585	61467608	17	-	26472758	K562	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	0.039404082314539624	[1003]	[870]	0	hSpCas9	negative selection	736054
61457536	61457559	17	+	26472758	K562	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.14220711616771292	[423]	[394]	1	hSpCas9	negative selection	736055
61457575	61457598	17	+	26472758	K562	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-1.3882405150860055	[368]	[118]	-6	hSpCas9	negative selection	736056
61465909	61465932	17	-	26472758	K562	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.6634692894519141	[717]	[959]	5	hSpCas9	negative selection	736057
61467621	61467644	17	+	26472758	K562	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.20655054207600398	[192]	[187]	1	hSpCas9	negative selection	736058
61478742	61478765	17	-	26472758	K562	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-2.562936194391157	[209]	[29]	-8	hSpCas9	negative selection	736059
61480260	61480283	17	+	26472758	K562	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	-0.25683306666547745	[1154]	[815]	-2	hSpCas9	negative selection	736060
61456663	61456686	17	-	26472758	K562	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	1.339996387648678	[72]	[155]	9	hSpCas9	negative selection	736061
61457606	61457629	17	+	26472758	K562	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	-0.28504866046300603	[152]	[105]	-2	hSpCas9	negative selection	736062
61456508	61456531	17	-	26627737	DLD1	viability	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.6037356474952255	[161]	[55,93,80]	6	hSpCas9	negative selection	799195
61457536	61457559	17	+	26627737	DLD1	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	1.081930197293471	[219]	[186,178,81]	8	hSpCas9	negative selection	799196
61465897	61465920	17	-	26627737	DLD1	viability	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.23489411231348245	[911]	[161,241,311]	-2	hSpCas9	negative selection	799197
61467621	61467644	17	+	26627737	DLD1	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	1.0856357519428186	[151]	[141,94,69]	8	hSpCas9	negative selection	799198
61478653	61478676	17	-	26627737	DLD1	viability	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	-0.39720788197000045	[228]	[85,11,61]	-4	hSpCas9	negative selection	799199
61480147	61480170	17	+	26627737	DLD1	viability	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	0.7048371555722459	[800]	[516,373,341]	7	hSpCas9	negative selection	799200
61456508	61456531	17	-	26627737	GBM cells	viability after 5 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	-0.18597502270082755	[139]	[53,77]	-3	hSpCas9	negative selection	881510
61457536	61457559	17	+	26627737	GBM cells	viability after 5 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.4913321805258893	[192]	[140,149]	7	hSpCas9	negative selection	881511
61465897	61465920	17	-	26627737	GBM cells	viability after 5 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.396092920686388	[291]	[98,138]	-6	hSpCas9	negative selection	881512
61467621	61467644	17	+	26627737	GBM cells	viability after 5 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.2272397409711986	[89]	[49,62]	3	hSpCas9	negative selection	881513
61478653	61478676	17	-	26627737	GBM cells	viability after 5 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.9655849145309733	[73]	[44,109]	9	hSpCas9	negative selection	881514
61480147	61480170	17	+	26627737	GBM cells	viability after 5 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	0.20623755686427614	[416]	[243,271]	3	hSpCas9	negative selection	881515
61456508	61456531	17	-	26627737	GBM cells	viability after 13 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	-0.5766277761215871	[139]	[56,45]	-6	hSpCas9	negative selection	963825
61457536	61457559	17	+	26627737	GBM cells	viability after 13 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.046006177190940134	[192]	[122,95]	0	hSpCas9	negative selection	963826
61465897	61465920	17	-	26627737	GBM cells	viability after 13 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.5749055737349471	[291]	[139,78]	-6	hSpCas9	negative selection	963827
61467621	61467644	17	+	26627737	GBM cells	viability after 13 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.18867417769589	[89]	[53,56]	2	hSpCas9	negative selection	963828
61478653	61478676	17	-	26627737	GBM cells	viability after 13 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.9303149086758508	[73]	[70,80]	9	hSpCas9	negative selection	963829
61480147	61480170	17	+	26627737	GBM cells	viability after 13 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	0.46570824071084216	[416]	[328,298]	6	hSpCas9	negative selection	963830
61456508	61456531	17	-	26627737	GBM cells	viability after 21 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	-0.5914732236022403	[139]	[50,49]	-5	hSpCas9	negative selection	1046140
61457536	61457559	17	+	26627737	GBM cells	viability after 21 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.08789534755091422	[192]	[94,101]	-1	hSpCas9	negative selection	1046141
61465897	61465920	17	-	26627737	GBM cells	viability after 21 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.13899849801337005	[291]	[165,123]	-1	hSpCas9	negative selection	1046142
61467621	61467644	17	+	26627737	GBM cells	viability after 21 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	1.0227475892864144	[89]	[102,95]	8	hSpCas9	negative selection	1046143
61478653	61478676	17	-	26627737	GBM cells	viability after 21 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.8302028110036725	[73]	[71,70]	7	hSpCas9	negative selection	1046144
61480147	61480170	17	+	26627737	GBM cells	viability after 21 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	0.10594979079486155	[416]	[259,228]	1	hSpCas9	negative selection	1046145
61456508	61456531	17	-	26627737	RPE1	viability after 9 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.5974344515923438	[235]	[161,46]	4	hSpCas9	negative selection	1128455
61457536	61457559	17	+	26627737	RPE1	viability after 9 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.05139484657767912	[639]	[119,287]	0	hSpCas9	negative selection	1128456
61465897	61465920	17	-	26627737	RPE1	viability after 9 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.6062692965850494	[1025]	[179,250]	-4	hSpCas9	negative selection	1128457
61467621	61467644	17	+	26627737	RPE1	viability after 9 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-1.1518362761060694	[537]	[39,121]	-7	hSpCas9	negative selection	1128458
61478653	61478676	17	-	26627737	RPE1	viability after 9 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	1.4255970914824347	[161]	[192,62]	7	hSpCas9	negative selection	1128459
61480147	61480170	17	+	26627737	RPE1	viability after 9 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	0.9308007249200583	[847]	[616,362]	6	hSpCas9	negative selection	1128460
61456508	61456531	17	-	26627737	RPE1	viability after 12 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.8030485826409245	[235]	[131,87]	5	hSpCas9	negative selection	1210770
61457536	61457559	17	+	26627737	RPE1	viability after 12 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.24822421888229973	[639]	[177,231]	1	hSpCas9	negative selection	1210771
61465897	61465920	17	-	26627737	RPE1	viability after 12 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	0.3069243250902562	[1025]	[357,322]	2	hSpCas9	negative selection	1210772
61467621	61467644	17	+	26627737	RPE1	viability after 12 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.07101429106875079	[537]	[55,223]	0	hSpCas9	negative selection	1210773
61478653	61478676	17	-	26627737	RPE1	viability after 12 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	1.5725921673569359	[161]	[178,76]	8	hSpCas9	negative selection	1210774
61480147	61480170	17	+	26627737	RPE1	viability after 12 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	0.8729838935998567	[847]	[493,335]	5	hSpCas9	negative selection	1210775
61456508	61456531	17	-	26627737	RPE1	viability after 15 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	1.0918380372396386	[235]	[181,103]	6	hSpCas9	negative selection	1293085
61457536	61457559	17	+	26627737	RPE1	viability after 15 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.0749585700643613	[639]	[206,137]	0	hSpCas9	negative selection	1293086
61465897	61465920	17	-	26627737	RPE1	viability after 15 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.2071318250606094	[1025]	[227,273]	-1	hSpCas9	negative selection	1293087
61467621	61467644	17	+	26627737	RPE1	viability after 15 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.5952556556537162	[537]	[2,194]	-4	hSpCas9	negative selection	1293088
61478653	61478676	17	-	26627737	RPE1	viability after 15 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	1.1000684170983452	[161]	[84,110]	6	hSpCas9	negative selection	1293089
61480147	61480170	17	+	26627737	RPE1	viability after 15 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	1.2005956238404984	[847]	[560,541]	7	hSpCas9	negative selection	1293090
61456508	61456531	17	-	26627737	RPE1	viability after 18 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.31977915238213406	[235]	[122,32]	2	hSpCas9	negative selection	1375400
61457536	61457559	17	+	26627737	RPE1	viability after 18 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.26737673206114254	[639]	[157,127]	-2	hSpCas9	negative selection	1375401
61465897	61465920	17	-	26627737	RPE1	viability after 18 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.058455646425298435	[1025]	[116,424]	0	hSpCas9	negative selection	1375402
61467621	61467644	17	+	26627737	RPE1	viability after 18 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.29070906851308653	[537]	[63,298]	1	hSpCas9	negative selection	1375403
61478653	61478676	17	-	26627737	RPE1	viability after 18 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	1.656954744496602	[161]	[235,32]	8	hSpCas9	negative selection	1375404
61480147	61480170	17	+	26627737	RPE1	viability after 18 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	0.9097657338491874	[847]	[544,306]	5	hSpCas9	negative selection	1375405
61456508	61456531	17	-	26627737	HeLa	viability after 8 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	1.848476084201348	[85]	[117,138,142]	9	hSpCas9	negative selection	1457715
61457536	61457559	17	+	26627737	HeLa	viability after 8 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.6639163150192549	[152]	[66,46,187]	6	hSpCas9	negative selection	1457716
61465897	61465920	17	-	26627737	HeLa	viability after 8 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	0.03267803047895235	[603]	[314,281,222]	0	hSpCas9	negative selection	1457717
61467621	61467644	17	+	26627737	HeLa	viability after 8 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	1.741258354376253	[86]	[75,127,161]	9	hSpCas9	negative selection	1457718
61478653	61478676	17	-	26627737	HeLa	viability after 8 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.14237243855812098	[205]	[77,141,73]	1	hSpCas9	negative selection	1457719
61480147	61480170	17	+	26627737	HeLa	viability after 8 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	1.4034396380657144	[324]	[480,248,412]	8	hSpCas9	negative selection	1457720
61456508	61456531	17	-	26627737	HeLa	viability after 12 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	1.7622396259654418	[85]	[89,146,120]	9	hSpCas9	negative selection	1540030
61457536	61457559	17	+	26627737	HeLa	viability after 12 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.025686773226026416	[152]	[66,65,59]	0	hSpCas9	negative selection	1540031
61465897	61465920	17	-	26627737	HeLa	viability after 12 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.1677817689171231	[603]	[325,114,239]	-1	hSpCas9	negative selection	1540032
61467621	61467644	17	+	26627737	HeLa	viability after 12 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.6863228739957719	[86]	[33,84,50]	5	hSpCas9	negative selection	1540033
61478653	61478676	17	-	26627737	HeLa	viability after 12 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	-1.1477555087296336	[205]	[36,49,26]	-8	hSpCas9	negative selection	1540034
61480147	61480170	17	+	26627737	HeLa	viability after 12 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	1.5261811536574412	[324]	[412,417,326]	8	hSpCas9	negative selection	1540035
61456508	61456531	17	-	26627737	HeLa	viability after 15 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.8462810149834996	[85]	[2,130,54]	6	hSpCas9	negative selection	1622345
61457536	61457559	17	+	26627737	HeLa	viability after 15 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	1.1682491455213322	[152]	[182,76,160]	8	hSpCas9	negative selection	1622346
61465897	61465920	17	-	26627737	HeLa	viability after 15 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.1293862578415702	[603]	[106,173,408]	-1	hSpCas9	negative selection	1622347
61467621	61467644	17	+	26627737	HeLa	viability after 15 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.7768939628470017	[86]	[42,69,69]	6	hSpCas9	negative selection	1622348
61478653	61478676	17	-	26627737	HeLa	viability after 15 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.6946883327781185	[205]	[192,22,194]	5	hSpCas9	negative selection	1622349
61480147	61480170	17	+	26627737	HeLa	viability after 15 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	1.314204213965346	[324]	[135,276,596]	8	hSpCas9	negative selection	1622350
61456508	61456531	17	-	26627737	HeLa	viability after 18 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.8697731697956661	[85]	[1,110,54]	6	hSpCas9	negative selection	1704660
61457536	61457559	17	+	26627737	HeLa	viability after 18 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	1.1661628870741176	[152]	[122,62,160]	7	hSpCas9	negative selection	1704661
61465897	61465920	17	-	26627737	HeLa	viability after 18 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.12035685098827359	[603]	[72,145,408]	-1	hSpCas9	negative selection	1704662
61467621	61467644	17	+	26627737	HeLa	viability after 18 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.8223551017155721	[86]	[30,59,69]	6	hSpCas9	negative selection	1704663
61478653	61478676	17	-	26627737	HeLa	viability after 18 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.6708185989673383	[205]	[125,17,194]	5	hSpCas9	negative selection	1704664
61480147	61480170	17	+	26627737	HeLa	viability after 18 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	1.3156866701726642	[324]	[92,227,596]	8	hSpCas9	negative selection	1704665
61456508	61456531	17	-	26627737	HCT116	viability after 6 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	2.1867531343058717	[254]	[41,259]	9	hSpCas9	negative selection	1786975
61457536	61457559	17	+	26627737	HCT116	viability after 6 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	1.4236832780356357	[306]	[220,78]	7	hSpCas9	negative selection	1786976
61465897	61465920	17	-	26627737	HCT116	viability after 6 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-2.3501926795143238	[1562]	[111,12]	-8	hSpCas9	negative selection	1786977
61467621	61467644	17	+	26627737	HCT116	viability after 6 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	2.1883647659332905	[137]	[7,148]	9	hSpCas9	negative selection	1786978
61478653	61478676	17	-	26627737	HCT116	viability after 6 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	3.2252059067788967	[277]	[88,584]	9	hSpCas9	negative selection	1786979
61480147	61480170	17	+	26627737	HCT116	viability after 6 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	0.7270809737512034	[1570]	[208,518]	4	hSpCas9	negative selection	1786980
61456508	61456531	17	-	26627737	HCT116	viability after 8 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.1530314990738868	[99]	[51,99,31]	1	hSpCas9	negative selection	1869290
61457536	61457559	17	+	26627737	HCT116	viability after 8 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	1.6885908742799345	[84]	[108,259,83]	9	hSpCas9	negative selection	1869291
61465897	61465920	17	-	26627737	HCT116	viability after 8 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.15594212137784913	[521]	[326,212,235]	-2	hSpCas9	negative selection	1869292
61467621	61467644	17	+	26627737	HCT116	viability after 8 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.4171300545385717	[162]	[107,83,166]	4	hSpCas9	negative selection	1869293
61478653	61478676	17	-	26627737	HCT116	viability after 8 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.28963188063536816	[81]	[45,20,97]	3	hSpCas9	negative selection	1869294
61480147	61480170	17	+	26627737	HCT116	viability after 8 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	0.1289869778723005	[633]	[377,385,381]	1	hSpCas9	negative selection	1869295
61456508	61456531	17	-	26627737	HCT116	viability after 9 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	-0.3984533026149717	[254]	[73,33]	-3	hSpCas9	negative selection	1951605
61457536	61457559	17	+	26627737	HCT116	viability after 9 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.493532624088878	[306]	[36,74]	-3	hSpCas9	negative selection	1951606
61465897	61465920	17	-	26627737	HCT116	viability after 9 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.7737890913229104	[1562]	[80,372]	-5	hSpCas9	negative selection	1951607
61467621	61467644	17	+	26627737	HCT116	viability after 9 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.2347701961900659	[137]	[58,30]	1	hSpCas9	negative selection	1951608
61478653	61478676	17	-	26627737	HCT116	viability after 9 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.5105318650571695	[277]	[7,182]	4	hSpCas9	negative selection	1951609
61480147	61480170	17	+	26627737	HCT116	viability after 9 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	-0.5287640452089186	[1570]	[292,288]	-4	hSpCas9	negative selection	1951610
61456508	61456531	17	-	26627737	HCT116	viability after 12 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.8792235097284722	[99]	[34,120,139]	7	hSpCas9	negative selection	2033920
61457536	61457559	17	+	26627737	HCT116	viability after 12 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	1.7423802312095842	[84]	[144,158,144]	9	hSpCas9	negative selection	2033921
61465897	61465920	17	-	26627737	HCT116	viability after 12 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	0.027448833218539748	[521]	[311,240,281]	0	hSpCas9	negative selection	2033922
61467621	61467644	17	+	26627737	HCT116	viability after 12 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.32523622871080415	[162]	[85,44,71]	-3	hSpCas9	negative selection	2033923
61478653	61478676	17	-	26627737	HCT116	viability after 12 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.929471818607531	[81]	[72,39,132]	7	hSpCas9	negative selection	2033924
61480147	61480170	17	+	26627737	HCT116	viability after 12 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	0.2307155229052189	[633]	[470,272,418]	2	hSpCas9	negative selection	2033925
61456508	61456531	17	-	26627737	HCT116	viability after 15 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.6629193233674783	[99]	[77,84,107]	6	hSpCas9	negative selection	2116235
61457536	61457559	17	+	26627737	HCT116	viability after 15 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	1.7657837722951928	[84]	[163,187,145]	9	hSpCas9	negative selection	2116236
61465897	61465920	17	-	26627737	HCT116	viability after 15 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.17889864979185155	[521]	[379,206,221]	-2	hSpCas9	negative selection	2116237
61467621	61467644	17	+	26627737	HCT116	viability after 15 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.1106627819539242	[162]	[209,48,57]	1	hSpCas9	negative selection	2116238
61478653	61478676	17	-	26627737	HCT116	viability after 15 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.7225925134819573	[81]	[77,63,90]	6	hSpCas9	negative selection	2116239
61480147	61480170	17	+	26627737	HCT116	viability after 15 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	-0.0998385018279283	[633]	[511,334,194]	-1	hSpCas9	negative selection	2116240
61456508	61456531	17	-	26627737	HCT116	viability after 18 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.09868743065495189	[99]	[43,48,62]	0	hSpCas9	negative selection	2198550
61457536	61457559	17	+	26627737	HCT116	viability after 18 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	1.4473117934184678	[84]	[137,102,94]	8	hSpCas9	negative selection	2198551
61465897	61465920	17	-	26627737	HCT116	viability after 18 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	0.2578957090624796	[521]	[289,248,372]	2	hSpCas9	negative selection	2198552
61467621	61467644	17	+	26627737	HCT116	viability after 18 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.4248647583192761	[162]	[132,131,47]	3	hSpCas9	negative selection	2198553
61478653	61478676	17	-	26627737	HCT116	viability after 18 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	1.0644407985240014	[81]	[84,53,112]	8	hSpCas9	negative selection	2198554
61480147	61480170	17	+	26627737	HCT116	viability after 18 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	0.23121811289916105	[633]	[421,422,223]	2	hSpCas9	negative selection	2198555
61456478	61456501	17	+	24336569	HL60	viability	GTGCCCGCAGGAGATGCTGCAGG	TBX4	ENSG00000121075	0.15874934446709665	[907]	[2144]	1	hSpCas9	negative selection	2299311
61456484	61456507	17	+	24336569	HL60	viability	GCAGGAGATGCTGCAGGATAAGG	TBX4	ENSG00000121075	-0.1741163048768306	[1261]	[2366]	-1	hSpCas9	negative selection	2299312
61456502	61456525	17	+	24336569	HL60	viability	TAAGGGCCTGTCCGAGAGCGAGG	TBX4	ENSG00000121075	0.7326239284377982	[396]	[1395]	6	hSpCas9	negative selection	2299313
61456508	61456531	17	-	24336569	HL60	viability	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.30381004514574417	[703]	[1838]	3	hSpCas9	negative selection	2299314
61456513	61456536	17	+	24336569	HL60	viability	CCGAGAGCGAGGAGGCCTTCCGG	TBX4	ENSG00000121075	-0.3663452087609388	[691]	[1135]	-3	hSpCas9	negative selection	2299315
61456544	61456567	17	-	24336569	HL60	viability	CGCTGGCCTCTCCGAGCGCTGGG	TBX4	ENSG00000121075	-1.2491167830616945	[792]	[705]	-8	hSpCas9	negative selection	2299316
61456590	61456613	17	+	24336569	HL60	viability	CTGGCAGCGCCGGGCCTCAGCGG	TBX4	ENSG00000121075	0.9617037585274775	[320]	[1322]	7	hSpCas9	negative selection	2299317
61456599	61456622	17	-	24336569	HL60	viability	AGCGCGGCTCCGCTGAGGCCCGG	TBX4	ENSG00000121075	0.8280956817556067	[287]	[1081]	6	hSpCas9	negative selection	2299318
61456604	61456627	17	-	24336569	HL60	viability	TGCCTAGCGCGGCTCCGCTGAGG	TBX4	ENSG00000121075	0.28322220317267344	[491]	[1266]	2	hSpCas9	negative selection	2299319
61456660	61456683	17	-	24336569	HL60	viability	CCCTACCTGCTCCGCGGCGGCGG	TBX4	ENSG00000121075	-0.149242215063756	[206]	[394]	-1	hSpCas9	negative selection	2299320
61456478	61456501	17	+	24336569	KBM7	viability	GTGCCCGCAGGAGATGCTGCAGG	TBX4	ENSG00000121075	-0.19697675550083282	[708]	[1686]	-2	hSpCas9	negative selection	2366488
61456484	61456507	17	+	24336569	KBM7	viability	GCAGGAGATGCTGCAGGATAAGG	TBX4	ENSG00000121075	0.3909490402981449	[568]	[2034]	3	hSpCas9	negative selection	2366489
61456502	61456525	17	+	24336569	KBM7	viability	TAAGGGCCTGTCCGAGAGCGAGG	TBX4	ENSG00000121075	0.41682546652768027	[339]	[1237]	4	hSpCas9	negative selection	2366490
61456508	61456531	17	-	24336569	KBM7	viability	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	-0.6723344575355845	[661]	[1132]	-5	hSpCas9	negative selection	2366491
61456513	61456536	17	+	24336569	KBM7	viability	CCGAGAGCGAGGAGGCCTTCCGG	TBX4	ENSG00000121075	0.8710569515801148	[350]	[1750]	7	hSpCas9	negative selection	2366492
61456544	61456567	17	-	24336569	KBM7	viability	CGCTGGCCTCTCCGAGCGCTGGG	TBX4	ENSG00000121075	-0.40193653099316995	[559]	[1155]	-3	hSpCas9	negative selection	2366493
61456590	61456613	17	+	24336569	KBM7	viability	CTGGCAGCGCCGGGCCTCAGCGG	TBX4	ENSG00000121075	0.8560026058578254	[458]	[2265]	7	hSpCas9	negative selection	2366494
61456599	61456622	17	-	24336569	KBM7	viability	AGCGCGGCTCCGCTGAGGCCCGG	TBX4	ENSG00000121075	0.4651539672334673	[229]	[865]	4	hSpCas9	negative selection	2366495
61456604	61456627	17	-	24336569	KBM7	viability	TGCCTAGCGCGGCTCCGCTGAGG	TBX4	ENSG00000121075	0.13830781240057183	[519]	[1560]	1	hSpCas9	negative selection	2366496
61456660	61456683	17	-	24336569	KBM7	viability	CCCTACCTGCTCCGCGGCGGCGG	TBX4	ENSG00000121075	4.14238398523064	[17]	[866]	9	hSpCas9	negative selection	2366497
61467120	61467143	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCACTCTGTCACCCATGCTAG	TBX4	ENSG00000121075	-1.0563295009396656	[70,78]	[6,7]	-6	dCas9-VP64	positive selection	2387698
61456323	61456346	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGAGGGAACCCGCAAGGAAGG	TBX4	ENSG00000121075	2.164094891409668	[20,5]	[22,2]	7	dCas9-VP64	positive selection	2450268
61456248	61456271	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTTCAATGTCTGCCTGCCCCTGG	TBX4	ENSG00000121075	-0.9858921443174553	[147,105]	[8,18]	-6	dCas9-VP64	positive selection	2450269
61456273	61456296	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGGACCTGGGAGGGTCTGCGG	TBX4	ENSG00000121075	-0.5586323059005225	[28,117]	[13,6]	-3	dCas9-VP64	positive selection	2450270
61478873	61478896	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGCCTGCCCAAGCCCTGCTGG	TBX4	ENSG00000121075	-0.7631534722234086	[122,108]	[20,7]	-4	dCas9-VP64	positive selection	2475990
61467120	61467143	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCACTCTGTCACCCATGCTAG	TBX4	ENSG00000121075	3.1967559695878185	[163,108]	[786,59]	9	dCas9-VP64	positive selection	2482953
61456323	61456346	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGAGGGAACCCGCAAGGAAGG	TBX4	ENSG00000121075	-0.6551341730447238	[124,15]	[17,10]	-6	dCas9-VP64	positive selection	2545523
61456248	61456271	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTTCAATGTCTGCCTGCCCCTGG	TBX4	ENSG00000121075	-0.3220767624309656	[225,186]	[38,66]	-3	dCas9-VP64	positive selection	2545524
61456273	61456296	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGGACCTGGGAGGGTCTGCGG	TBX4	ENSG00000121075	-0.5561840828553557	[56,30]	[8,9]	-5	dCas9-VP64	positive selection	2545525
61478873	61478896	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGCCTGCCCAAGCCCTGCTGG	TBX4	ENSG00000121075	0.14775808396027768	[91,61]	[32,22]	1	dCas9-VP64	positive selection	2571245
61456599	61456622	17	-	27260157	DLD1	viability	AGCGCGGCTCCGCTGAGGCCCGG	TBX4	ENSG00000121075	-0.883820167964045	[]	[]	-6	hSpCas9	negative selection	2576473
61456508	61456531	17	-	27260157	DLD1	viability	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.5412130377101	[]	[]	8	hSpCas9	negative selection	2578416
61456478	61456501	17	+	27260157	DLD1	viability	GTGCCCGCAGGAGATGCTGCAGG	TBX4	ENSG00000121075	0.449182150818393	[]	[]	7	hSpCas9	negative selection	2580445
61457590	61457613	17	-	27260157	DLD1	viability	TCATCTCGGTGCCCGCCTCGTGG	TBX4	ENSG00000121075	0.416998081014491	[]	[]	7	hSpCas9	negative selection	2581812
61456544	61456567	17	-	27260157	DLD1	viability	CGCTGGCCTCTCCGAGCGCTGGG	TBX4	ENSG00000121075	0.749588951686445	[]	[]	8	hSpCas9	negative selection	2585119
61456604	61456627	17	-	27260157	DLD1	viability	TGCCTAGCGCGGCTCCGCTGAGG	TBX4	ENSG00000121075	-1.16873599166089	[]	[]	-7	hSpCas9	negative selection	2586883
61467582	61467605	17	+	27260157	DLD1	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.571752063686676	[]	[]	8	hSpCas9	negative selection	2586931
61456502	61456525	17	+	27260157	DLD1	viability	TAAGGGCCTGTCCGAGAGCGAGG	TBX4	ENSG00000121075	-0.068053569230247	[]	[]	0	hSpCas9	negative selection	2587440
61457533	61457556	17	+	27260157	DLD1	viability	CCAGACCATCGAGAACATCAAGG	TBX4	ENSG00000121075	1.83157688040102	[]	[]	9	hSpCas9	negative selection	2611244
61465897	61465920	17	-	27260157	DLD1	viability	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.675363990043357	[]	[]	-5	hSpCas9	negative selection	2612046
61456663	61456686	17	-	27260157	DLD1	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.364063843466299	[]	[]	4	hSpCas9	negative selection	2613950
61478665	61478688	17	-	27260157	DLD1	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.514160638139038	[]	[]	-4	hSpCas9	negative selection	2618366
61456484	61456507	17	+	27260157	DLD1	viability	GCAGGAGATGCTGCAGGATAAGG	TBX4	ENSG00000121075	0.921625483321937	[]	[]	9	hSpCas9	negative selection	2620554
61457575	61457598	17	+	27260157	DLD1	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	0.919001325928829	[]	[]	9	hSpCas9	negative selection	2620794
61456513	61456536	17	+	27260157	DLD1	viability	CCGAGAGCGAGGAGGCCTTCCGG	TBX4	ENSG00000121075	1.12936515957572	[]	[]	9	hSpCas9	negative selection	2621536
61456660	61456683	17	-	27260157	DLD1	viability	CCCTACCTGCTCCGCGGCGGCGG	TBX4	ENSG00000121075	-0.16476619592064	[]	[]	-1	hSpCas9	negative selection	2641285
61456590	61456613	17	+	27260157	DLD1	viability	CTGGCAGCGCCGGGCCTCAGCGG	TBX4	ENSG00000121075	-0.0499101042290303	[]	[]	0	hSpCas9	negative selection	2644601
61467621	61467644	17	+	27260157	DLD1	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.193235216045182	[]	[]	-1	hSpCas9	negative selection	2648099
61456599	61456622	17	-	27260157	HT1080	viability	AGCGCGGCTCCGCTGAGGCCCGG	TBX4	ENSG00000121075	0.575936549898693	[]	[]	5	hSpCas9	negative selection	2652603
61456508	61456531	17	-	27260157	HT1080	viability	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	-0.0588905367552224	[]	[]	0	hSpCas9	negative selection	2654546
61456478	61456501	17	+	27260157	HT1080	viability	GTGCCCGCAGGAGATGCTGCAGG	TBX4	ENSG00000121075	1.17083921850042	[]	[]	8	hSpCas9	negative selection	2656575
61457590	61457613	17	-	27260157	HT1080	viability	TCATCTCGGTGCCCGCCTCGTGG	TBX4	ENSG00000121075	0.350632724149867	[]	[]	3	hSpCas9	negative selection	2657942
61456544	61456567	17	-	27260157	HT1080	viability	CGCTGGCCTCTCCGAGCGCTGGG	TBX4	ENSG00000121075	0.963587954842538	[]	[]	7	hSpCas9	negative selection	2661249
61456604	61456627	17	-	27260157	HT1080	viability	TGCCTAGCGCGGCTCCGCTGAGG	TBX4	ENSG00000121075	0.319755887132959	[]	[]	3	hSpCas9	negative selection	2663013
61467582	61467605	17	+	27260157	HT1080	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	1.00430048787857	[]	[]	8	hSpCas9	negative selection	2663061
61456502	61456525	17	+	27260157	HT1080	viability	TAAGGGCCTGTCCGAGAGCGAGG	TBX4	ENSG00000121075	0.569180848880348	[]	[]	5	hSpCas9	negative selection	2663570
61457533	61457556	17	+	27260157	HT1080	viability	CCAGACCATCGAGAACATCAAGG	TBX4	ENSG00000121075	1.46823400711174	[]	[]	9	hSpCas9	negative selection	2687374
61465897	61465920	17	-	27260157	HT1080	viability	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	0.114484857630274	[]	[]	1	hSpCas9	negative selection	2688176
61456663	61456686	17	-	27260157	HT1080	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	-0.282040107218612	[]	[]	-7	hSpCas9	negative selection	2690080
61478665	61478688	17	-	27260157	HT1080	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.651938875418053	[]	[]	6	hSpCas9	negative selection	2694496
61456484	61456507	17	+	27260157	HT1080	viability	GCAGGAGATGCTGCAGGATAAGG	TBX4	ENSG00000121075	0.836147044706824	[]	[]	7	hSpCas9	negative selection	2696684
61457575	61457598	17	+	27260157	HT1080	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.280382507012923	[]	[]	-4	hSpCas9	negative selection	2696924
61456513	61456536	17	+	27260157	HT1080	viability	CCGAGAGCGAGGAGGCCTTCCGG	TBX4	ENSG00000121075	1.07265863326877	[]	[]	8	hSpCas9	negative selection	2697666
61456660	61456683	17	-	27260157	HT1080	viability	CCCTACCTGCTCCGCGGCGGCGG	TBX4	ENSG00000121075	-0.176853524340045	[]	[]	0	hSpCas9	negative selection	2717415
61456590	61456613	17	+	27260157	HT1080	viability	CTGGCAGCGCCGGGCCTCAGCGG	TBX4	ENSG00000121075	-0.674302916171454	[]	[]	-8	hSpCas9	negative selection	2720731
61467621	61467644	17	+	27260157	HT1080	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	2.14089886005267	[]	[]	9	hSpCas9	negative selection	2724229
61456599	61456622	17	-	27260157	MKN45	viability	AGCGCGGCTCCGCTGAGGCCCGG	TBX4	ENSG00000121075	-0.207751127049267	[]	[]	0	hSpCas9	negative selection	2728733
61456508	61456531	17	-	27260157	MKN45	viability	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	-0.265406567965998	[]	[]	-1	hSpCas9	negative selection	2730676
61456478	61456501	17	+	27260157	MKN45	viability	GTGCCCGCAGGAGATGCTGCAGG	TBX4	ENSG00000121075	0.83016383882696	[]	[]	8	hSpCas9	negative selection	2732705
61457590	61457613	17	-	27260157	MKN45	viability	TCATCTCGGTGCCCGCCTCGTGG	TBX4	ENSG00000121075	0.21680107051797	[]	[]	5	hSpCas9	negative selection	2734072
61456544	61456567	17	-	27260157	MKN45	viability	CGCTGGCCTCTCCGAGCGCTGGG	TBX4	ENSG00000121075	1.15881339054461	[]	[]	8	hSpCas9	negative selection	2737379
61456604	61456627	17	-	27260157	MKN45	viability	TGCCTAGCGCGGCTCCGCTGAGG	TBX4	ENSG00000121075	-0.201379029654837	[]	[]	0	hSpCas9	negative selection	2739143
61467582	61467605	17	+	27260157	MKN45	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.535571949056687	[]	[]	6	hSpCas9	negative selection	2739191
61456502	61456525	17	+	27260157	MKN45	viability	TAAGGGCCTGTCCGAGAGCGAGG	TBX4	ENSG00000121075	1.13035551248929	[]	[]	8	hSpCas9	negative selection	2739700
61457533	61457556	17	+	27260157	MKN45	viability	CCAGACCATCGAGAACATCAAGG	TBX4	ENSG00000121075	1.08276315912023	[]	[]	8	hSpCas9	negative selection	2763504
61465897	61465920	17	-	27260157	MKN45	viability	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.117864231840015	[]	[]	0	hSpCas9	negative selection	2764306
61456663	61456686	17	-	27260157	MKN45	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	-0.762303900801194	[]	[]	-7	hSpCas9	negative selection	2766210
61478665	61478688	17	-	27260157	MKN45	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.595095156197052	[]	[]	7	hSpCas9	negative selection	2770626
61456484	61456507	17	+	27260157	MKN45	viability	GCAGGAGATGCTGCAGGATAAGG	TBX4	ENSG00000121075	1.10000991503224	[]	[]	8	hSpCas9	negative selection	2772814
61457575	61457598	17	+	27260157	MKN45	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.430213536294531	[]	[]	-6	hSpCas9	negative selection	2773054
61456513	61456536	17	+	27260157	MKN45	viability	CCGAGAGCGAGGAGGCCTTCCGG	TBX4	ENSG00000121075	1.3743809680365	[]	[]	9	hSpCas9	negative selection	2773796
61456660	61456683	17	-	27260157	MKN45	viability	CCCTACCTGCTCCGCGGCGGCGG	TBX4	ENSG00000121075	-0.566319037616794	[]	[]	-6	hSpCas9	negative selection	2793545
61456590	61456613	17	+	27260157	MKN45	viability	CTGGCAGCGCCGGGCCTCAGCGG	TBX4	ENSG00000121075	0.235647426770353	[]	[]	5	hSpCas9	negative selection	2796861
61467621	61467644	17	+	27260157	MKN45	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	1.68912614810204	[]	[]	9	hSpCas9	negative selection	2800359
61456599	61456622	17	-	27260157	RKO	viability	AGCGCGGCTCCGCTGAGGCCCGG	TBX4	ENSG00000121075	0.461211005828584	[]	[]	2	hSpCas9	negative selection	2804863
61456508	61456531	17	-	27260157	RKO	viability	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.343425871909015	[]	[]	1	hSpCas9	negative selection	2806806
61456478	61456501	17	+	27260157	RKO	viability	GTGCCCGCAGGAGATGCTGCAGG	TBX4	ENSG00000121075	0.265083897655422	[]	[]	1	hSpCas9	negative selection	2808835
61457590	61457613	17	-	27260157	RKO	viability	TCATCTCGGTGCCCGCCTCGTGG	TBX4	ENSG00000121075	0.310781711884687	[]	[]	1	hSpCas9	negative selection	2810202
61456544	61456567	17	-	27260157	RKO	viability	CGCTGGCCTCTCCGAGCGCTGGG	TBX4	ENSG00000121075	0.0903652558480361	[]	[]	0	hSpCas9	negative selection	2813509
61456604	61456627	17	-	27260157	RKO	viability	TGCCTAGCGCGGCTCCGCTGAGG	TBX4	ENSG00000121075	-0.203002221551154	[]	[]	-1	hSpCas9	negative selection	2815273
61467582	61467605	17	+	27260157	RKO	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.68751410861391	[]	[]	7	hSpCas9	negative selection	2815321
61456502	61456525	17	+	27260157	RKO	viability	TAAGGGCCTGTCCGAGAGCGAGG	TBX4	ENSG00000121075	0.278904374974072	[]	[]	1	hSpCas9	negative selection	2815830
61457533	61457556	17	+	27260157	RKO	viability	CCAGACCATCGAGAACATCAAGG	TBX4	ENSG00000121075	1.81010345359461	[]	[]	9	hSpCas9	negative selection	2839634
61465897	61465920	17	-	27260157	RKO	viability	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	0.44592463072595	[]	[]	2	hSpCas9	negative selection	2840436
61456663	61456686	17	-	27260157	RKO	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.387883392488503	[]	[]	2	hSpCas9	negative selection	2842340
61478665	61478688	17	-	27260157	RKO	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.165056202845791	[]	[]	0	hSpCas9	negative selection	2846756
61456484	61456507	17	+	27260157	RKO	viability	GCAGGAGATGCTGCAGGATAAGG	TBX4	ENSG00000121075	0.507098550146536	[]	[]	2	hSpCas9	negative selection	2848944
61457575	61457598	17	+	27260157	RKO	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.338748468100817	[]	[]	-6	hSpCas9	negative selection	2849184
61456513	61456536	17	+	27260157	RKO	viability	CCGAGAGCGAGGAGGCCTTCCGG	TBX4	ENSG00000121075	0.619579985146042	[]	[]	3	hSpCas9	negative selection	2849926
61456660	61456683	17	-	27260157	RKO	viability	CCCTACCTGCTCCGCGGCGGCGG	TBX4	ENSG00000121075	-0.721514785020899	[]	[]	-7	hSpCas9	negative selection	2869675
61456590	61456613	17	+	27260157	RKO	viability	CTGGCAGCGCCGGGCCTCAGCGG	TBX4	ENSG00000121075	-0.674422688279219	[]	[]	-7	hSpCas9	negative selection	2872991
61467621	61467644	17	+	27260157	RKO	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	2.02152136260161	[]	[]	9	hSpCas9	negative selection	2876489
61456599	61456622	17	-	27260157	SF268	viability	AGCGCGGCTCCGCTGAGGCCCGG	TBX4	ENSG00000121075	0.400732265013553	[]	[]	4	hSpCas9	negative selection	2880993
61456508	61456531	17	-	27260157	SF268	viability	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.597605459665405	[]	[]	8	hSpCas9	negative selection	2882936
61456478	61456501	17	+	27260157	SF268	viability	GTGCCCGCAGGAGATGCTGCAGG	TBX4	ENSG00000121075	0.39469764644176	[]	[]	4	hSpCas9	negative selection	2884965
61457590	61457613	17	-	27260157	SF268	viability	TCATCTCGGTGCCCGCCTCGTGG	TBX4	ENSG00000121075	1.27895144099416	[]	[]	9	hSpCas9	negative selection	2886332
61456544	61456567	17	-	27260157	SF268	viability	CGCTGGCCTCTCCGAGCGCTGGG	TBX4	ENSG00000121075	0.954693816928978	[]	[]	9	hSpCas9	negative selection	2889639
61456604	61456627	17	-	27260157	SF268	viability	TGCCTAGCGCGGCTCCGCTGAGG	TBX4	ENSG00000121075	0.385219497941783	[]	[]	4	hSpCas9	negative selection	2891403
61467582	61467605	17	+	27260157	SF268	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.502574774265318	[]	[]	7	hSpCas9	negative selection	2891451
61456502	61456525	17	+	27260157	SF268	viability	TAAGGGCCTGTCCGAGAGCGAGG	TBX4	ENSG00000121075	0.0442411734421583	[]	[]	0	hSpCas9	negative selection	2891960
61457533	61457556	17	+	27260157	SF268	viability	CCAGACCATCGAGAACATCAAGG	TBX4	ENSG00000121075	1.05547477494882	[]	[]	9	hSpCas9	negative selection	2915764
61465897	61465920	17	-	27260157	SF268	viability	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.289972947424881	[]	[]	-2	hSpCas9	negative selection	2916566
61456663	61456686	17	-	27260157	SF268	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.275183650105299	[]	[]	4	hSpCas9	negative selection	2918470
61478665	61478688	17	-	27260157	SF268	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.45421794485717	[]	[]	-4	hSpCas9	negative selection	2922886
61456484	61456507	17	+	27260157	SF268	viability	GCAGGAGATGCTGCAGGATAAGG	TBX4	ENSG00000121075	1.37575327319343	[]	[]	9	hSpCas9	negative selection	2925074
61457575	61457598	17	+	27260157	SF268	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	0.301491837961219	[]	[]	4	hSpCas9	negative selection	2925314
61456513	61456536	17	+	27260157	SF268	viability	CCGAGAGCGAGGAGGCCTTCCGG	TBX4	ENSG00000121075	1.17660769578775	[]	[]	9	hSpCas9	negative selection	2926056
61456660	61456683	17	-	27260157	SF268	viability	CCCTACCTGCTCCGCGGCGGCGG	TBX4	ENSG00000121075	-0.792010166258179	[]	[]	-6	hSpCas9	negative selection	2945805
61456590	61456613	17	+	27260157	SF268	viability	CTGGCAGCGCCGGGCCTCAGCGG	TBX4	ENSG00000121075	-0.275173961537438	[]	[]	-2	hSpCas9	negative selection	2949121
61467621	61467644	17	+	27260157	SF268	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	1.98703858931061	[]	[]	9	hSpCas9	negative selection	2952619
61478641	61478664	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTATGCACAAGTACCAGCCGCGG	TBX4	ENSG00000121075	0.3271696967655171	[3,3]	[3,4]	7	hSpCas9	positive selection	3025797
61478657	61478680	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCTTAACGATGTGGAGCCGCGG	TBX4	ENSG00000121075	-0.3167799866601651	[2,2]	[2,0]	-4	hSpCas9	positive selection	3025798
61456666	61456689	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCAGCCCTACCTGCTCCGCGG	TBX4	ENSG00000121075	-1.2752936779672546	[2,1]	[0,0]	-9	hSpCas9	positive selection	3025799
61457576	61457599	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.0917665954693144	[3,2]	[3,1]	-1	hSpCas9	positive selection	3025800
61478641	61478664	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTATGCACAAGTACCAGCCGCGG	TBX4	ENSG00000121075	-0.09155575180021183	[3,3]	[3,1]	-1	hSpCas9	positive selection	3093655
61478657	61478680	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCTTAACGATGTGGAGCCGCGG	TBX4	ENSG00000121075	0.8953540750547404	[2,2]	[1,4]	9	hSpCas9	positive selection	3093656
61456666	61456689	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCAGCCCTACCTGCTCCGCGG	TBX4	ENSG00000121075	-0.15057471747482154	[2,2]	[2,0]	-2	hSpCas9	positive selection	3093657
61457576	61457599	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.6095980658857447	[3,3]	[2,0]	-8	hSpCas9	positive selection	3093658
61467582	61467605		+	24336571	A375	resistance to PLX after 7 days	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.2574092332335297	[10,11]	[13,13]	7	hSpCas9	positive selection	3149348
61467621	61467644		+	24336571	A375	resistance to PLX after 7 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.07638936260914164	[3,4]	[4,2]	-2	hSpCas9	positive selection	3149350
61465819	61465842		+	24336571	A375	resistance to PLX after 7 days	GAGGATGTTCCCCAGCTACAAGG	TBX4	ENSG00000121075	-0.18090754865171246	[14,14]	[11,13]	-6	hSpCas9	positive selection	3149351
61465909	61465932		-	24336571	A375	resistance to PLX after 7 days	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.44432172907611434	[15,10]	[8,9]	-9	hSpCas9	positive selection	3149352
61467582	61467605		+	24336571	A375	resistance to PLX after 14 days	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.2617794218167513	[11,12]	[3,5]	-3	hSpCas9	positive selection	3207141
61467621	61467644		+	24336571	A375	resistance to PLX after 14 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.15707033804978066	[4,4]	[1,1]	-2	hSpCas9	positive selection	3207143
61465819	61465842		+	24336571	A375	resistance to PLX after 14 days	GAGGATGTTCCCCAGCTACAAGG	TBX4	ENSG00000121075	-0.27642825080314626	[18,14]	[6,5]	-3	hSpCas9	positive selection	3207144
61465909	61465932		-	24336571	A375	resistance to PLX after 14 days	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.5108460342511687	[15,11]	[3,4]	-6	hSpCas9	positive selection	3207145
61467582	61467605		+	24336571	A375	viability after 7 days	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.1381473021279608	[10]	[10,11]	2	hSpCas9	negative selection	3264934
61467621	61467644		+	24336571	A375	viability after 7 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-1.0173417670382916	[9]	[3,4]	-9	hSpCas9	negative selection	3264936
61465819	61465842		+	24336571	A375	viability after 7 days	GAGGATGTTCCCCAGCTACAAGG	TBX4	ENSG00000121075	0.346174149564325	[11]	[14,14]	5	hSpCas9	negative selection	3264937
61465909	61465932		-	24336571	A375	viability after 7 days	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.1523859693916826	[14]	[15,10]	-2	hSpCas9	negative selection	3264938
61467582	61467605		+	24336571	A375	viability after 14 days	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.3075788631043625	[10]	[11,12]	4	hSpCas9	negative selection	3322727
61467621	61467644		+	24336571	A375	viability after 14 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.9134634380428207	[9]	[4,4]	-8	hSpCas9	negative selection	3322729
61465819	61465842		+	24336571	A375	viability after 14 days	GAGGATGTTCCCCAGCTACAAGG	TBX4	ENSG00000121075	0.5550044589790253	[11]	[18,14]	7	hSpCas9	negative selection	3322730
61465909	61465932		-	24336571	A375	viability after 14 days	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.027015601868659922	[14]	[15,11]	0	hSpCas9	negative selection	3322731
61478632	61478655	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	1.7233476394434837	[138,138]	[2,2]	7	hSpCas9	positive selection	3396446
61467646	61467669	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.3504356158373165	[119,119]	[0,0]	1	hSpCas9	positive selection	3396447
61465879	61465902	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	-2.128536189195626	[668,668]	[0,0]	-9	hSpCas9	positive selection	3396448
61478640	61478663	17	+	26780180	HT29	viability (Avana library 4 designs)	CTATGCACAAGTACCAGCCGCGG	TBX4	ENSG00000121075	1.76029270864013	[]	[]	6	hSpCas9	negative selection	3464511
61478657	61478680	17	-	26780180	HT29	viability (Avana library 4 designs)	GCCTTAACGATGTGGAGCCGCGG	TBX4	ENSG00000121075	2.82312124817077	[]	[]	8	hSpCas9	negative selection	3464512
61456666	61456689	17	-	26780180	HT29	viability (Avana library 4 designs)	GCGCAGCCCTACCTGCTCCGCGG	TBX4	ENSG00000121075	0.445069188352226	[]	[]	1	hSpCas9	negative selection	3464513
61457575	61457598	17	+	26780180	HT29	viability (Avana library 4 designs)	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	1.06410290838368	[]	[]	4	hSpCas9	negative selection	3464514
61457575	61457598	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	1.18619510106333	[]	[]	1	hSpCas9	negative selection	3567238
61478640	61478663	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTATGCACAAGTACCAGCCGCGG	TBX4	ENSG00000121075	3.94500840261643	[]	[]	6	hSpCas9	negative selection	3567239
61478657	61478680	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTTAACGATGTGGAGCCGCGG	TBX4	ENSG00000121075	5.58963241095361	[]	[]	8	hSpCas9	negative selection	3567240
61456666	61456689	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCAGCCCTACCTGCTCCGCGG	TBX4	ENSG00000121075	5.85798020994928	[]	[]	9	hSpCas9	negative selection	3567241
61457536	61457559	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-2.10575822726528	[]	[]	-3	hSpCas9	negative selection	3567242
61478724	61478747	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGTCTCTGGGAACACGTGGG	TBX4	ENSG00000121075	-0.268026346164937	[]	[]	0	hSpCas9	negative selection	3567243
61457575	61457598	17	+	26780180	A375	viability (Avana lentiGuide)	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	6.66501106082978	[]	[]	5	hSpCas9	negative selection	3675897
61478640	61478663	17	+	26780180	A375	viability (Avana lentiGuide)	CTATGCACAAGTACCAGCCGCGG	TBX4	ENSG00000121075	2.62641366544451	[]	[]	2	hSpCas9	negative selection	3675898
61478657	61478680	17	-	26780180	A375	viability (Avana lentiGuide)	GCCTTAACGATGTGGAGCCGCGG	TBX4	ENSG00000121075	7.10697415090539	[]	[]	5	hSpCas9	negative selection	3675899
61456666	61456689	17	-	26780180	A375	viability (Avana lentiGuide)	GCGCAGCCCTACCTGCTCCGCGG	TBX4	ENSG00000121075	10.698405961878	[]	[]	7	hSpCas9	negative selection	3675900
61457536	61457559	17	+	26780180	A375	viability (Avana lentiGuide)	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	4.43018147129634	[]	[]	4	hSpCas9	negative selection	3675901
61478724	61478747	17	-	26780180	A375	viability (Avana lentiGuide)	GGAGGTCTCTGGGAACACGTGGG	TBX4	ENSG00000121075	0.53666209543947	[]	[]	0	hSpCas9	negative selection	3675902
61457575	61457598	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.33976104533892576	[3]	[3,1]	-5	hSpCas9	positive selection	3784504
61478640	61478663	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTATGCACAAGTACCAGCCGCGG	TBX4	ENSG00000121075	0.05270348548910048	[5]	[6,4]	1	hSpCas9	positive selection	3784505
61478657	61478680	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTTAACGATGTGGAGCCGCGG	TBX4	ENSG00000121075	0.24936347627872282	[3]	[5,4]	7	hSpCas9	positive selection	3784506
61456666	61456689	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCAGCCCTACCTGCTCCGCGG	TBX4	ENSG00000121075	0.4117077110846732	[4]	[5,5]	9	hSpCas9	positive selection	3784507
61457536	61457559	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.6036725815265127	[4]	[2,2]	-7	hSpCas9	positive selection	3784508
61478724	61478747	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGTCTCTGGGAACACGTGGG	TBX4	ENSG00000121075	-0.19630333205580855	[5]	[4,4]	-3	hSpCas9	positive selection	3784509
61457575	61457598	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	0.17371123242646952	[5]	[4,4]	4	hSpCas9	positive selection	3893111
61478640	61478663	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTATGCACAAGTACCAGCCGCGG	TBX4	ENSG00000121075	-0.33344255599624284	[6]	[3,4]	-4	hSpCas9	positive selection	3893112
61478657	61478680	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTTAACGATGTGGAGCCGCGG	TBX4	ENSG00000121075	0.09950371394863244	[4]	[4,3]	2	hSpCas9	positive selection	3893113
61456666	61456689	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCAGCCCTACCTGCTCCGCGG	TBX4	ENSG00000121075	-0.5226562051172053	[3]	[1,1]	-6	hSpCas9	positive selection	3893114
61457536	61457559	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.11339333191822051	[4]	[2,4]	-1	hSpCas9	positive selection	3893115
61478724	61478747	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGTCTCTGGGAACACGTGGG	TBX4	ENSG00000121075	0.20378433569651988	[6]	[7,5]	5	hSpCas9	positive selection	3893116
61467582	61467605	17	+	26780180	A375	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.528144186513555	[]	[]	1	hSpCas9	negative selection	4002517
61465879	61465902	17	-	26780180	A375	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.775336319206346	[]	[]	3	hSpCas9	negative selection	4002518
61467646	61467669	17	-	26780180	A375	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.712060301682782	[]	[]	2	hSpCas9	negative selection	4002519
61478632	61478655	17	-	26780180	A375	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	1.18085643892043	[]	[]	6	hSpCas9	negative selection	4002520
61478665	61478688	17	-	26780180	A375	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	1.01409926872715	[]	[]	5	hSpCas9	negative selection	4002521
61465909	61465932	17	-	26780180	A375	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	1.54757434485873	[]	[]	8	hSpCas9	negative selection	4002522
61467582	61467605	17	+	26780180	HT29	viability (GeCKOv2 library)	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.83936505372274	[]	[]	3	hSpCas9	negative selection	4110483
61465879	61465902	17	-	26780180	HT29	viability (GeCKOv2 library)	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.611294225399194	[]	[]	2	hSpCas9	negative selection	4110484
61467646	61467669	17	-	26780180	HT29	viability (GeCKOv2 library)	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	1.20785214224491	[]	[]	6	hSpCas9	negative selection	4110485
61478632	61478655	17	-	26780180	HT29	viability (GeCKOv2 library)	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	1.16742655427213	[]	[]	5	hSpCas9	negative selection	4110486
61478665	61478688	17	-	26780180	HT29	viability (GeCKOv2 library)	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.611858463828086	[]	[]	2	hSpCas9	negative selection	4110487
61465909	61465932	17	-	26780180	HT29	viability (GeCKOv2 library)	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.943465831682489	[]	[]	4	hSpCas9	negative selection	4110488
61467582	61467605	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.01971140232072481	[3]	[2,1]	0	hSpCas9	positive selection	4175681
61467621	61467644	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.850632324498451	[1]	[5,0]	9	hSpCas9	positive selection	4175683
61465819	61465842	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGGATGTTCCCCAGCTACAAGG	TBX4	ENSG00000121075	-0.1055003622921357	[3]	[1,2]	-2	hSpCas9	positive selection	4175684
61465909	61465932	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.16679792250689227	[4]	[2,1]	-4	hSpCas9	positive selection	4175685
61467582	61467605	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.05144126355619874	[4]	[3,0,3,0]	0	hSpCas9	positive selection	4239703
61467621	61467644	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.10242771408273654	[2]	[0,0,2,0]	-1	hSpCas9	positive selection	4239705
61465819	61465842	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGGATGTTCCCCAGCTACAAGG	TBX4	ENSG00000121075	0.25211682288391773	[3]	[1,2,4,0]	2	hSpCas9	positive selection	4239706
61465909	61465932	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.3191161628034156	[1]	[0,1,1,0]	2	hSpCas9	positive selection	4239707
61478665	61478688	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.07474402333012792	[4]	[4,1]	-1	hSpCas9	positive selection	4302292
61465909	61465932	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.23168936514087476	[2]	[2,1]	-5	hSpCas9	positive selection	4302293
61467582	61467605	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.3920313893931191	[0]	[0,0]	-7	hSpCas9	positive selection	4302294
61478632	61478655	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.04897470174177587	[2]	[2,1]	-1	hSpCas9	positive selection	4366546
61467646	61467669	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	-0.26927265000138917	[2]	[2,0]	-5	hSpCas9	positive selection	4366547
61465879	61465902	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.2730241717752343	[4]	[4,3]	5	hSpCas9	positive selection	4366548
61465830	61465852	17	-	27760321	OCIAML3	viability	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	0.4347616673900424	[264,283]	[294,287]	5	hSpCas9	negative selection	4445744
61467647	61467669	17	-	27760321	OCIAML3	viability	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	0.6091302132278094	[573,491]	[606,668]	7	hSpCas9	negative selection	4445745
61478665	61478687	17	-	27760321	OCIAML3	viability	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.374496864835824	[419,404]	[135,396]	-4	hSpCas9	negative selection	4445746
61478760	61478782	17	-	27760321	OCIAML3	viability	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	0.6673821185065888	[425,355]	[395,597]	7	hSpCas9	negative selection	4445747
61479949	61479971	17	+	27760321	OCIAML3	viability	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	-0.6479411087064592	[818,677]	[354,393]	-6	hSpCas9	negative selection	4445748
61465830	61465852	17	-	27760321	OCIAML2	viability	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	0.7200749600676726	[264,283]	[383,346]	8	hSpCas9	negative selection	4529207
61467647	61467669	17	-	27760321	OCIAML2	viability	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	0.3218221219951006	[573,491]	[472,621]	4	hSpCas9	negative selection	4529208
61478665	61478687	17	-	27760321	OCIAML2	viability	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.4395220074824222	[419,404]	[214,287]	-5	hSpCas9	negative selection	4529209
61478760	61478782	17	-	27760321	OCIAML2	viability	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	0.7418413096390805	[425,355]	[512,544]	8	hSpCas9	negative selection	4529210
61479949	61479971	17	+	27760321	OCIAML2	viability	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	-0.3630481904308565	[818,677]	[532,383]	-4	hSpCas9	negative selection	4529211
61465830	61465852	17	-	27760321	MV411	viability	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	0.19709651530366162	[264,283]	[126,331]	1	hSpCas9	negative selection	4612670
61467647	61467669	17	-	27760321	MV411	viability	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	-0.042174221405000295	[573,491]	[290,414]	0	hSpCas9	negative selection	4612671
61478665	61478687	17	-	27760321	MV411	viability	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.6549086624581966	[419,404]	[165,183]	-4	hSpCas9	negative selection	4612672
61478760	61478782	17	-	27760321	MV411	viability	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	1.4664498948384614	[425,355]	[614,852]	9	hSpCas9	negative selection	4612673
61479949	61479971	17	+	27760321	MV411	viability	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	-0.9171285205949715	[818,677]	[267,248]	-6	hSpCas9	negative selection	4612674
61465830	61465852	17	-	27760321	HL60	viability	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	-0.3762818368030133	[264,283]	[150,197]	-4	hSpCas9	negative selection	4696133
61467647	61467669	17	-	27760321	HL60	viability	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	0.5340457787123944	[573,491]	[695,556]	6	hSpCas9	negative selection	4696134
61478665	61478687	17	-	27760321	HL60	viability	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.34689266986448597	[419,404]	[439,417]	4	hSpCas9	negative selection	4696135
61478760	61478782	17	-	27760321	HL60	viability	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	0.8924875748662965	[425,355]	[706,466]	8	hSpCas9	negative selection	4696136
61479949	61479971	17	+	27760321	HL60	viability	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	-0.2489355874920126	[818,677]	[337,696]	-3	hSpCas9	negative selection	4696137
61465830	61465852	17	-	27760321	HT1080	viability	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	-1.2921359101643355	[283,221]	[33,48]	-5	hSpCas9	negative selection	4779596
61467647	61467669	17	-	27760321	HT1080	viability	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	0.83161427987196	[491,383]	[268,355]	4	hSpCas9	negative selection	4779597
61478665	61478687	17	-	27760321	HT1080	viability	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-1.4901426099726054	[404,315]	[0,105]	-5	hSpCas9	negative selection	4779598
61478760	61478782	17	-	27760321	HT1080	viability	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	1.1376639284158103	[355,277]	[274,280]	6	hSpCas9	negative selection	4779599
61479949	61479971	17	+	27760321	HT1080	viability	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	-0.786092615469702	[677,528]	[221,48]	-3	hSpCas9	negative selection	4779600
61465830	61465852	17	-	27760321	HT29	viability after 7 days	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	-0.6955954853956149	[283,221]	[186,169,241]	-7	hSpCas9	negative selection	4863059
61467647	61467669	17	-	27760321	HT29	viability after 7 days	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	0.7252049302830016	[491,383]	[1039,897,870]	9	hSpCas9	negative selection	4863060
61478665	61478687	17	-	27760321	HT29	viability after 7 days	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.018869927483206383	[404,315]	[615,375,437]	0	hSpCas9	negative selection	4863061
61478760	61478782	17	-	27760321	HT29	viability after 7 days	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	0.31880860493119356	[355,277]	[425,461,620]	5	hSpCas9	negative selection	4863062
61479949	61479971	17	+	27760321	HT29	viability after 7 days	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	0.2802171880123169	[677,528]	[1055,982,806]	4	hSpCas9	negative selection	4863063
61465830	61465852	17	-	27760321	HT29	viability after 25 days	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	-0.5132380165418523	[283,221]	[200,234,167]	-5	hSpCas9	negative selection	4946522
61467647	61467669	17	-	27760321	HT29	viability after 25 days	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	0.875319998737263	[491,383]	[821,780,1183]	8	hSpCas9	negative selection	4946523
61478665	61478687	17	-	27760321	HT29	viability after 25 days	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.0930348952019252	[404,315]	[440,281,436]	-1	hSpCas9	negative selection	4946524
61478760	61478782	17	-	27760321	HT29	viability after 25 days	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	0.5628169064760139	[355,277]	[289,519,841]	6	hSpCas9	negative selection	4946525
61479949	61479971	17	+	27760321	HT29	viability after 25 days	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	-0.26490520882372837	[677,528]	[588,704,408]	-3	hSpCas9	negative selection	4946526
61465830	61465852	17	-	27760321	HT29	viability after 22 days	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	0.057042046319729756	[283,221]	[393,366,147]	0	hSpCas9	negative selection	5029985
61467647	61467669	17	-	27760321	HT29	viability after 22 days	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	1.066043733639888	[491,383]	[1318,937,914]	9	hSpCas9	negative selection	5029986
61478665	61478687	17	-	27760321	HT29	viability after 22 days	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.058970931187158994	[404,315]	[429,300,468]	0	hSpCas9	negative selection	5029987
61478760	61478782	17	-	27760321	HT29	viability after 22 days	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	0.32016033968153523	[355,277]	[407,501,463]	3	hSpCas9	negative selection	5029988
61479949	61479971	17	+	27760321	HT29	viability after 22 days	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	-0.29819660623221117	[677,528]	[664,414,619]	-3	hSpCas9	negative selection	5029989
61465830	61465852	17	-	27760321	HT29	viability after 19 days	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	-0.5640109061433122	[283,221]	[122,247,207]	-5	hSpCas9	negative selection	5113448
61467647	61467669	17	-	27760321	HT29	viability after 19 days	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	0.7840664626237338	[491,383]	[1192,866,572]	7	hSpCas9	negative selection	5113449
61478665	61478687	17	-	27760321	HT29	viability after 19 days	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.0592478497665341	[404,315]	[464,393,432]	0	hSpCas9	negative selection	5113450
61478760	61478782	17	-	27760321	HT29	viability after 19 days	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	0.7755951363438112	[355,277]	[524,985,350]	7	hSpCas9	negative selection	5113451
61479949	61479971	17	+	27760321	HT29	viability after 19 days	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	0.13484249297756046	[677,528]	[894,706,687]	1	hSpCas9	negative selection	5113452
61465830	61465852	17	-	27760321	HT29	viability after 16 days	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	-0.1792115158950751	[283,221]	[192,158,394]	-2	hSpCas9	negative selection	5196911
61467647	61467669	17	-	27760321	HT29	viability after 16 days	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	0.817140854160043	[491,383]	[793,882,905]	8	hSpCas9	negative selection	5196912
61478665	61478687	17	-	27760321	HT29	viability after 16 days	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.060680441848420766	[404,315]	[536,281,357]	0	hSpCas9	negative selection	5196913
61478760	61478782	17	-	27760321	HT29	viability after 16 days	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	0.37741167141200294	[355,277]	[412,444,519]	4	hSpCas9	negative selection	5196914
61479949	61479971	17	+	27760321	HT29	viability after 16 days	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	0.030644876582681113	[677,528]	[786,617,674]	0	hSpCas9	negative selection	5196915
61465830	61465852	17	-	27760321	HT29	viability after 13 days	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	-0.528013134889986	[283,221]	[180,281,150]	-5	hSpCas9	negative selection	5280374
61467647	61467669	17	-	27760321	HT29	viability after 13 days	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	0.8456929372773004	[491,383]	[1128,869,749]	9	hSpCas9	negative selection	5280375
61478665	61478687	17	-	27760321	HT29	viability after 13 days	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.05298373017222853	[404,315]	[375,395,523]	0	hSpCas9	negative selection	5280376
61478760	61478782	17	-	27760321	HT29	viability after 13 days	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	0.05027989934776042	[355,277]	[422,299,416]	0	hSpCas9	negative selection	5280377
61479949	61479971	17	+	27760321	HT29	viability after 13 days	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	-0.013190790371657268	[677,528]	[667,750,663]	0	hSpCas9	negative selection	5280378
61465830	61465852	17	-	27760321	HT29	viability after 10 days	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	-1.3138301159922925	[283,221]	[251,86,42]	-8	hSpCas9	negative selection	5363837
61467647	61467669	17	-	27760321	HT29	viability after 10 days	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	0.4661670451949196	[491,383]	[724,843,700]	6	hSpCas9	negative selection	5363838
61478665	61478687	17	-	27760321	HT29	viability after 10 days	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.014399920345202356	[404,315]	[457,443,434]	0	hSpCas9	negative selection	5363839
61478760	61478782	17	-	27760321	HT29	viability after 10 days	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	0.07546815759391183	[355,277]	[384,388,474]	1	hSpCas9	negative selection	5363840
61479949	61479971	17	+	27760321	HT29	viability after 10 days	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	0.007725210383430436	[677,528]	[786,854,635]	0	hSpCas9	negative selection	5363841
61465830	61465852	17	-	27760321	MOLM13	viability	GTGACTTTTACCTTGTAGCTGG	TBX4	ENSG00000121075	0.44116094664908706	[264,283]	[156,257]	3	hSpCas9	negative selection	5447300
61467647	61467669	17	-	27760321	MOLM13	viability	CCCATGCTTACATGGCCAAAGG	TBX4	ENSG00000121075	1.1070012162956195	[573,491]	[742,562]	7	hSpCas9	negative selection	5447301
61478665	61478687	17	-	27760321	MOLM13	viability	CTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.5527722168073782	[419,404]	[462,238]	4	hSpCas9	negative selection	5447302
61478760	61478782	17	-	27760321	MOLM13	viability	ACCTTGTGATTCTGGTAGGAGG	TBX4	ENSG00000121075	1.9958916952548633	[425,355]	[555,1148]	9	hSpCas9	negative selection	5447303
61479949	61479971	17	+	27760321	MOLM13	viability	GCGTGTGGCCCGACTGCAGAGG	TBX4	ENSG00000121075	-0.26346342602268913	[818,677]	[124,541]	-2	hSpCas9	negative selection	5447304
61452697	61452720	17	+	27661255	K562	viability	GACCCGGGGAAGAACTTCAGGGG	TBX4	ENSG00000121075	0.4457410072553468	[744,829]	[900,815]	9	dCas9-KRAB	negative selection	5516271
61456289	61456312	17	+	27661255	K562	viability	GTCCACAGCCTGAAGGGAGGAGG	TBX4	ENSG00000121075	-0.23701231286793156	[320,382]	[219,252]	-6	dCas9-KRAB	negative selection	5516272
61456677	61456700	17	+	27661255	K562	viability	GTAGGGCTGCGCCAGCCGTCGGG	TBX4	ENSG00000121075	-0.3025553165639331	[1134,1037]	[767,650]	-7	dCas9-KRAB	negative selection	5516273
61452398	61452421	17	-	27661255	K562	viability	GAGCGGGCCCTTGATCTCCAAGG	TBX4	ENSG00000121075	-0.048915092952984796	[1310,1396]	[1154,949]	-2	dCas9-KRAB	negative selection	5516274
61452415	61452438	17	-	27661255	K562	viability	GACACATCCCGGCTCTGGAGCGG	TBX4	ENSG00000121075	0.18673781043020643	[261,272]	[289,202]	6	dCas9-KRAB	negative selection	5516275
61452467	61452490	17	-	27661255	K562	viability	GACTCCGCGCCGCTGGGTCAGGG	TBX4	ENSG00000121075	0.11696521403280549	[643,554]	[571,476]	4	dCas9-KRAB	negative selection	5516276
61452783	61452806	17	-	27661255	K562	viability	GGGCTCGTGCCCCAACTACTGGG	TBX4	ENSG00000121075	0.40782443240331023	[18,11]	[8,22]	9	dCas9-KRAB	negative selection	5516277
61452889	61452912	17	-	27661255	K562	viability	GGCCACCGCTCCGCCTGTCACGG	TBX4	ENSG00000121075	0.21754595490278295	[662,737]	[738,572]	7	dCas9-KRAB	negative selection	5516278
61456323	61456346	17	-	27661255	K562	viability	GAGGAGGGAACCCGCAAGGAAGG	TBX4	ENSG00000121075	-0.28971934030998214	[595,591]	[398,378]	-6	dCas9-KRAB	negative selection	5516279
61456327	61456350	17	-	27661255	K562	viability	GCTGGAGGAGGGAACCCGCAAGG	TBX4	ENSG00000121075	-0.036924698555991786	[937,896]	[762,673]	-1	dCas9-KRAB	negative selection	5516280
61456692	61456715	17	-	27661255	K562	viability	GACGCCCGACTTCTACCCGACGG	TBX4	ENSG00000121075	0.1114704233628625	[1085,1198]	[1116,870]	4	dCas9-KRAB	negative selection	5516281
61456730	61456753	17	-	27661255	K562	viability	GACGGAAAGACGGACACAGGCGG	TBX4	ENSG00000121075	0.08173700691214913	[1425,1398]	[1329,1078]	3	dCas9-KRAB	negative selection	5516282
61478665	61478688	17	-	27260156	BXPC3	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.057900106942785134	[1096]	[944,1143,1262,1059]	-1	hSpCas9	negative selection	5574752
61465909	61465932	17	-	27260156	BXPC3	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.2134054972206244	[364]	[328,280,395,309]	-5	hSpCas9	negative selection	5574753
61467582	61467605	17	+	27260156	BXPC3	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.15600862605499755	[40]	[59,24,40,66]	3	hSpCas9	negative selection	5574754
61478632	61478655	17	-	27260156	BXPC3	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.16489942114646716	[331]	[348,243,278,370]	-4	hSpCas9	negative selection	5639006
61467646	61467669	17	-	27260156	BXPC3	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.3629676456287032	[308]	[368,361,417,532]	7	hSpCas9	negative selection	5639007
61465879	61465902	17	-	27260156	BXPC3	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.06542546403853988	[1406]	[1218,1436,1745,1824]	1	hSpCas9	negative selection	5639008
61478665	61478688	17	-	27260156	A673	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.042400069513412575	[1096]	[1523,1181,1294,1451]	1	hSpCas9	negative selection	5696003
61465909	61465932	17	-	27260156	A673	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.0030868837655433357	[364]	[436,438,391,490]	0	hSpCas9	negative selection	5696004
61467582	61467605	17	+	27260156	A673	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.724807525073738	[40]	[27,16,30,43]	-9	hSpCas9	negative selection	5696005
61478632	61478655	17	-	27260156	A673	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	0.13907976014652396	[331]	[490,429,410,428]	3	hSpCas9	negative selection	5760257
61467646	61467669	17	-	27260156	A673	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	-0.0760000475972834	[308]	[366,359,343,336]	-2	hSpCas9	negative selection	5760258
61465879	61465902	17	-	27260156	A673	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	-0.008092979117144017	[1406]	[1735,1507,1632,1860]	0	hSpCas9	negative selection	5760259
61478665	61478688	17	-	27260156	A375	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.11037180800045232	[1096]	[1384,1430,974,1008]	-2	hSpCas9	negative selection	5817254
61465909	61465932	17	-	27260156	A375	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.3908322235094023	[364]	[437,312,328,229]	-5	hSpCas9	negative selection	5817255
61467582	61467605	17	+	27260156	A375	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.5715918544476852	[40]	[83,18,16,9]	-6	hSpCas9	negative selection	5817256
61478632	61478655	17	-	27260156	A375	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	0.3449624289358071	[331]	[502,505,633,344]	5	hSpCas9	negative selection	5881508
61467646	61467669	17	-	27260156	A375	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.4907463166949171	[308]	[589,485,558,401]	7	hSpCas9	negative selection	5881509
61465879	61465902	17	-	27260156	A375	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.16399196858109333	[1406]	[1778,1824,2187,1592]	2	hSpCas9	negative selection	5881510
61478665	61478688	17	-	27260156	COLO741	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.015680040030081388	[1096]	[1610,1503,1167]	0	hSpCas9	negative selection	5938505
61465909	61465932	17	-	27260156	COLO741	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.3359848670357365	[364]	[400,336,371]	-6	hSpCas9	negative selection	5938506
61467582	61467605	17	+	27260156	COLO741	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.48970659824622453	[40]	[24,50,34]	-8	hSpCas9	negative selection	5938507
61478632	61478655	17	-	27260156	COLO741	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.054668029289318465	[331]	[394,290,527]	-1	hSpCas9	negative selection	6002759
61467646	61467669	17	-	27260156	COLO741	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.24127556364790798	[308]	[517,456,430]	5	hSpCas9	negative selection	6002760
61465879	61465902	17	-	27260156	COLO741	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.0779662773173111	[1406]	[2003,1917,1783]	1	hSpCas9	negative selection	6002761
61478665	61478688	17	-	27260156	CAL120	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.039416975869196236	[1096]	[1686,1116,1235]	0	hSpCas9	negative selection	6059756
61465909	61465932	17	-	27260156	CAL120	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.10134681639290671	[364]	[463,382,428]	-1	hSpCas9	negative selection	6059757
61467582	61467605	17	+	27260156	CAL120	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.0722008949847579	[40]	[118,34,2]	-1	hSpCas9	negative selection	6059758
61478632	61478655	17	-	27260156	CAL120	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	0.2726812576749832	[331]	[735,313,482]	4	hSpCas9	negative selection	6124010
61467646	61467669	17	-	27260156	CAL120	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.037121107179338475	[308]	[452,330,407]	0	hSpCas9	negative selection	6124011
61465879	61465902	17	-	27260156	CAL120	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	-0.002921936789789026	[1406]	[1615,1329,2265]	0	hSpCas9	negative selection	6124012
61478665	61478688	17	-	27260156	CADOES1	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.2305862367977276	[1096]	[846,740,1122,762]	-4	hSpCas9	negative selection	6181007
61465909	61465932	17	-	27260156	CADOES1	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.4809540162252345	[364]	[181,356,275,154]	-7	hSpCas9	negative selection	6181008
61467582	61467605	17	+	27260156	CADOES1	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.16451830828367697	[40]	[10,42,74,41]	3	hSpCas9	negative selection	6181009
61478632	61478655	17	-	27260156	CADOES1	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.5687442927265164	[331]	[222,198,142,269]	-7	hSpCas9	negative selection	6245261
61467646	61467669	17	-	27260156	CADOES1	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.3164465250987359	[308]	[406,364,336,320]	5	hSpCas9	negative selection	6245262
61465879	61465902	17	-	27260156	CADOES1	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.21291900505000005	[1406]	[1439,1438,1461,1733]	3	hSpCas9	negative selection	6245263
61478665	61478688	17	-	27260156	EWS502	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.08488245193413135	[1096]	[1213,1117,1068,1550]	1	hSpCas9	negative selection	6302258
61465909	61465932	17	-	27260156	EWS502	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.018243477052583612	[364]	[422,187,401,525]	0	hSpCas9	negative selection	6302259
61467582	61467605	17	+	27260156	EWS502	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.10812006615301639	[40]	[40,77,21,44]	1	hSpCas9	negative selection	6302260
61478632	61478655	17	-	27260156	EWS502	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.14040648582072013	[331]	[355,284,322,306]	-3	hSpCas9	negative selection	6366512
61467646	61467669	17	-	27260156	EWS502	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	-0.007102510800444217	[308]	[238,375,281,418]	0	hSpCas9	negative selection	6366513
61465879	61465902	17	-	27260156	EWS502	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.19484359774270077	[1406]	[1492,1769,1646,1945]	3	hSpCas9	negative selection	6366514
61478665	61478688	17	-	27260156	EW8	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.09911360782346668	[1096]	[977,1060,819,972]	1	hSpCas9	negative selection	6423509
61465909	61465932	17	-	27260156	EW8	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.0262469714588478	[364]	[316,212,280,353]	0	hSpCas9	negative selection	6423510
61467582	61467605	17	+	27260156	EW8	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.9586154693894993	[40]	[29,19,9,10]	-9	hSpCas9	negative selection	6423511
61478632	61478655	17	-	27260156	EW8	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	0.08021485295745806	[331]	[444,266,187,270]	1	hSpCas9	negative selection	6487763
61467646	61467669	17	-	27260156	EW8	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.5823577962887445	[308]	[446,396,308,364]	8	hSpCas9	negative selection	6487764
61465879	61465902	17	-	27260156	EW8	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.07496277951192765	[1406]	[1398,1163,911,1395]	1	hSpCas9	negative selection	6487765
61478665	61478688	17	-	27260156	CORL105	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.12279973851966641	[1096]	[1432,993,1216,1091]	-2	hSpCas9	negative selection	6544760
61465909	61465932	17	-	27260156	CORL105	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.25144253619522694	[364]	[345,345,368,375]	-5	hSpCas9	negative selection	6544761
61467582	61467605	17	+	27260156	CORL105	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.3579744739327153	[40]	[17,50,25,51]	-6	hSpCas9	negative selection	6544762
61478632	61478655	17	-	27260156	CORL105	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.11513918847061522	[331]	[293,294,553,321]	-2	hSpCas9	negative selection	6609014
61467646	61467669	17	-	27260156	CORL105	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	-0.21127068727910991	[308]	[340,353,254,290]	-4	hSpCas9	negative selection	6609015
61465879	61465902	17	-	27260156	CORL105	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	-0.13095415453972348	[1406]	[1716,1411,1791,1150]	-2	hSpCas9	negative selection	6609016
61478665	61478688	17	-	27260156	HS294T	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.09387175543413928	[1096]	[424,430,421,550]	1	hSpCas9	negative selection	6666011
61465909	61465932	17	-	27260156	HS294T	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.3806964364880103	[364]	[135,53,105,141]	-5	hSpCas9	negative selection	6666012
61467582	61467605	17	+	27260156	HS294T	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-1.317839699767935	[40]	[4,5,5,8]	-9	hSpCas9	negative selection	6666013
61478632	61478655	17	-	27260156	HS294T	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.16686326199763635	[331]	[84,103,107,172]	-2	hSpCas9	negative selection	6730265
61467646	61467669	17	-	27260156	HS294T	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.11357323728417368	[308]	[122,114,143,136]	1	hSpCas9	negative selection	6730266
61465879	61465902	17	-	27260156	HS294T	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.010116647112444088	[1406]	[389,628,660,516]	0	hSpCas9	negative selection	6730267
61478665	61478688	17	-	27260156	HCC44	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.051265054288085254	[1096]	[1117,1176,1254,1233]	-1	hSpCas9	negative selection	6787262
61465909	61465932	17	-	27260156	HCC44	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.015281059334831426	[364]	[359,501,629,166]	0	hSpCas9	negative selection	6787263
61467582	61467605	17	+	27260156	HCC44	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-1.0048753365257377	[40]	[58,18,12,3]	-8	hSpCas9	negative selection	6787264
61478632	61478655	17	-	27260156	HCC44	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	0.05806902791966839	[331]	[545,264,367,408]	0	hSpCas9	negative selection	6851516
61467646	61467669	17	-	27260156	HCC44	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	-0.005665104552349254	[308]	[331,239,507,350]	0	hSpCas9	negative selection	6851517
61465879	61465902	17	-	27260156	HCC44	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.11646684685264597	[1406]	[1668,1406,2364,1599]	1	hSpCas9	negative selection	6851518
61478665	61478688	17	-	27260156	G402	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.011265049759069834	[1096]	[1670,1532,1072,1102]	0	hSpCas9	negative selection	6908513
61465909	61465932	17	-	27260156	G402	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.5097009267852506	[364]	[465,307,250,249]	-6	hSpCas9	negative selection	6908514
61467582	61467605	17	+	27260156	G402	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.39839102450298736	[40]	[50,94,113,5]	5	hSpCas9	negative selection	6908515
61478632	61478655	17	-	27260156	G402	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.040988884318081675	[331]	[620,185,578,216]	0	hSpCas9	negative selection	6972767
61467646	61467669	17	-	27260156	G402	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.4355898531953061	[308]	[512,568,520,441]	5	hSpCas9	negative selection	6972768
61465879	61465902	17	-	27260156	G402	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.04936688970303704	[1406]	[1675,2310,1246,1876]	0	hSpCas9	negative selection	6972769
61478665	61478688	17	-	27260156	L33	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.049731993168832034	[1096]	[1216,494,555,1227]	1	hSpCas9	negative selection	7029764
61465909	61465932	17	-	27260156	L33	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.04154912062053784	[364]	[239,178,242,357]	-1	hSpCas9	negative selection	7029765
61467582	61467605	17	+	27260156	L33	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.5436194905093026	[40]	[35,3,29,18]	-8	hSpCas9	negative selection	7029766
61478632	61478655	17	-	27260156	L33	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.2784789239799893	[331]	[274,102,165,303]	-6	hSpCas9	negative selection	7094018
61467646	61467669	17	-	27260156	L33	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.16786383421751067	[308]	[334,137,245,325]	3	hSpCas9	negative selection	7094019
61465879	61465902	17	-	27260156	L33	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	-0.0974970648370923	[1406]	[1327,453,821,1513]	-2	hSpCas9	negative selection	7094020
61478665	61478688	17	-	27260156	K562	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.006624508368439752	[1096]	[972,903,977,1040]	0	hSpCas9	negative selection	7151015
61465909	61465932	17	-	27260156	K562	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.30310392755057747	[364]	[245,349,247,213]	-4	hSpCas9	negative selection	7151016
61467582	61467605	17	+	27260156	K562	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-1.47070756246247	[40]	[6,25,9,9]	-9	hSpCas9	negative selection	7151017
61478632	61478655	17	-	27260156	K562	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.295206262923449	[331]	[337,386,121,139]	-4	hSpCas9	negative selection	7215269
61467646	61467669	17	-	27260156	K562	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.7909420725937448	[308]	[308,432,483,634]	8	hSpCas9	negative selection	7215270
61465879	61465902	17	-	27260156	K562	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.24406614366664536	[1406]	[1062,1176,1603,1957]	3	hSpCas9	negative selection	7215271
61478665	61478688	17	-	27260156	HT29	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.07947722939792179	[1096]	[1282,1541,1321,955]	-2	hSpCas9	negative selection	7272266
61465909	61465932	17	-	27260156	HT29	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.06538810177593413	[364]	[414,572,655,242]	1	hSpCas9	negative selection	7272267
61467582	61467605	17	+	27260156	HT29	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.4270413999071634	[40]	[86,7,49,7]	-7	hSpCas9	negative selection	7272268
61478632	61478655	17	-	27260156	HT29	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.3652035820065038	[331]	[354,293,356,253]	-6	hSpCas9	negative selection	7336520
61467646	61467669	17	-	27260156	HT29	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.3336549364901466	[308]	[648,383,426,439]	6	hSpCas9	negative selection	7336521
61465879	61465902	17	-	27260156	HT29	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.14226200329468464	[1406]	[1775,2127,1938,1725]	2	hSpCas9	negative selection	7336522
61478665	61478688	17	-	27260156	MHHES1	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.10196435073002097	[1096]	[1033,1681,1356,1224]	2	hSpCas9	negative selection	7393517
61465909	61465932	17	-	27260156	MHHES1	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.06396448743966504	[364]	[286,762,359,336]	1	hSpCas9	negative selection	7393518
61467582	61467605	17	+	27260156	MHHES1	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.610579000712121	[40]	[49,39,10,23]	-8	hSpCas9	negative selection	7393519
61478632	61478655	17	-	27260156	MHHES1	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.06255024949907328	[331]	[613,338,284,241]	-1	hSpCas9	negative selection	7457771
61467646	61467669	17	-	27260156	MHHES1	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	-0.07889300662463494	[308]	[373,472,293,215]	-1	hSpCas9	negative selection	7457772
61465879	61465902	17	-	27260156	MHHES1	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.06445144828994898	[1406]	[1821,1897,1652,1336]	1	hSpCas9	negative selection	7457773
61478665	61478688	17	-	27260156	MEWO	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.026211401357393305	[1096]	[900,1296,907]	0	hSpCas9	negative selection	7514768
61465909	61465932	17	-	27260156	MEWO	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.09291119344105936	[364]	[460,269,256]	-2	hSpCas9	negative selection	7514769
61467582	61467605	17	+	27260156	MEWO	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-1.0501357947167853	[40]	[35,8,13]	-9	hSpCas9	negative selection	7514770
61478632	61478655	17	-	27260156	MEWO	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.6208963058375526	[331]	[263,181,171]	-8	hSpCas9	negative selection	7579022
61467646	61467669	17	-	27260156	MEWO	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.19191366920422848	[308]	[253,292,428]	4	hSpCas9	negative selection	7579023
61465879	61465902	17	-	27260156	MEWO	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	-0.1522348108766265	[1406]	[1355,1080,1149]	-3	hSpCas9	negative selection	7579024
61478665	61478688	17	-	27260156	LNCAPCLONEFGC	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.14885401286890443	[1096]	[897,841,847,992]	-2	hSpCas9	negative selection	7636019
61465909	61465932	17	-	27260156	LNCAPCLONEFGC	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.055257137633924036	[364]	[363,358,263,273]	-1	hSpCas9	negative selection	7636020
61467582	61467605	17	+	27260156	LNCAPCLONEFGC	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.016041361225615614	[40]	[54,27,8,50]	0	hSpCas9	negative selection	7636021
61478632	61478655	17	-	27260156	LNCAPCLONEFGC	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	0.004245220001743377	[331]	[381,321,244,245]	0	hSpCas9	negative selection	7700273
61467646	61467669	17	-	27260156	LNCAPCLONEFGC	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.18405111646455313	[308]	[318,214,448,314]	3	hSpCas9	negative selection	7700274
61465879	61465902	17	-	27260156	LNCAPCLONEFGC	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.25740360307147103	[1406]	[1211,1397,1770,1762]	4	hSpCas9	negative selection	7700275
61478665	61478688	17	-	27260156	PANC0327	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.1890655344513832	[1096]	[931,851,1019,621]	-3	hSpCas9	negative selection	7757270
61465909	61465932	17	-	27260156	PANC0327	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.3060272054660979	[364]	[331,410,281,570]	4	hSpCas9	negative selection	7757271
61467582	61467605	17	+	27260156	PANC0327	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.20545293904403916	[40]	[6,12,127,20]	3	hSpCas9	negative selection	7757272
61478632	61478655	17	-	27260156	PANC0327	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.22847745183089585	[331]	[221,199,251,336]	-3	hSpCas9	negative selection	7821524
61467646	61467669	17	-	27260156	PANC0327	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.06324597514235564	[308]	[297,394,242,197]	0	hSpCas9	negative selection	7821525
61465879	61465902	17	-	27260156	PANC0327	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.3167599057101753	[1406]	[1596,1264,1895,1509]	5	hSpCas9	negative selection	7821526
61478665	61478688	17	-	27260156	NCIH2009	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.1505809093494288	[1096]	[1663,1102,1433]	-2	hSpCas9	negative selection	7878521
61465909	61465932	17	-	27260156	NCIH2009	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.3844794113570873	[364]	[265,537,339]	-5	hSpCas9	negative selection	7878522
61467582	61467605	17	+	27260156	NCIH2009	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.47801073177822806	[40]	[104,35,103]	6	hSpCas9	negative selection	7878523
61478632	61478655	17	-	27260156	NCIH2009	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.41901583098113915	[331]	[489,373,203]	-5	hSpCas9	negative selection	7942775
61467646	61467669	17	-	27260156	NCIH2009	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.47808909633711805	[308]	[379,835,538]	6	hSpCas9	negative selection	7942776
61465879	61465902	17	-	27260156	NCIH2009	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.07963848072842317	[1406]	[2915,1709,1774]	1	hSpCas9	negative selection	7942777
61478665	61478688	17	-	27260156	NCIH1373	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.11862677831463087	[1096]	[1918,1155,1409,244]	1	hSpCas9	negative selection	7999772
61465909	61465932	17	-	27260156	NCIH1373	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.25246576593406533	[364]	[293,618,83,89]	-3	hSpCas9	negative selection	7999773
61467582	61467605	17	+	27260156	NCIH1373	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.033096748051474556	[40]	[65,27,87,1]	0	hSpCas9	negative selection	7999774
61478632	61478655	17	-	27260156	NCIH1373	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.9691110769314727	[331]	[244,150,206,43]	-7	hSpCas9	negative selection	8064026
61467646	61467669	17	-	27260156	NCIH1373	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.8896457112485806	[308]	[800,397,713,184]	8	hSpCas9	negative selection	8064027
61465879	61465902	17	-	27260156	NCIH1373	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.28692515423749976	[1406]	[2287,1625,2575,322]	3	hSpCas9	negative selection	8064028
61478665	61478688	17	-	27260156	PATU8902	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.25997927278636035	[1096]	[1180,1694,882,1460]	-3	hSpCas9	negative selection	8121023
61465909	61465932	17	-	27260156	PATU8902	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-1.7587300036408415	[364]	[195,189,34,215]	-8	hSpCas9	negative selection	8121024
61467582	61467605	17	+	27260156	PATU8902	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.31533542912639945	[40]	[52,214,1,26]	3	hSpCas9	negative selection	8121025
61478632	61478655	17	-	27260156	PATU8902	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.42646479559156925	[331]	[393,552,127,355]	-4	hSpCas9	negative selection	8185277
61467646	61467669	17	-	27260156	PATU8902	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.6314750706033996	[308]	[739,642,630,653]	6	hSpCas9	negative selection	8185278
61465879	61465902	17	-	27260156	PATU8902	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	-0.11493266594804274	[1406]	[2217,1833,1072,2348]	-1	hSpCas9	negative selection	8185279
61478665	61478688	17	-	27260156	PANC1	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.052009787859481404	[1096]	[934,1118,1046,842]	0	hSpCas9	negative selection	8242274
61465909	61465932	17	-	27260156	PANC1	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.2665225103068716	[364]	[259,255,252,266]	-4	hSpCas9	negative selection	8242275
61467582	61467605	17	+	27260156	PANC1	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-1.5131209926777127	[40]	[1,40,11,1]	-9	hSpCas9	negative selection	8242276
61478632	61478655	17	-	27260156	PANC1	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	0.06564184334096351	[331]	[338,223,478,155]	1	hSpCas9	negative selection	8306528
61467646	61467669	17	-	27260156	PANC1	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.2794719144862229	[308]	[341,489,380,135]	4	hSpCas9	negative selection	8306529
61465879	61465902	17	-	27260156	PANC1	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	-0.04754810452600022	[1406]	[1260,1580,973,957]	-1	hSpCas9	negative selection	8306530
61478665	61478688	17	-	27260156	PANC0813	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.12204685385201808	[1096]	[1488,1669,1237,1226]	2	hSpCas9	negative selection	8363525
61465909	61465932	17	-	27260156	PANC0813	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.10250406158024189	[364]	[474,462,395,504]	1	hSpCas9	negative selection	8363526
61467582	61467605	17	+	27260156	PANC0813	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.7218599161059767	[40]	[62,13,33,9]	-8	hSpCas9	negative selection	8363527
61478632	61478655	17	-	27260156	PANC0813	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.24910494793842697	[331]	[372,315,229,392]	-4	hSpCas9	negative selection	8427779
61467646	61467669	17	-	27260156	PANC0813	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.20073562954808094	[308]	[396,493,396,379]	3	hSpCas9	negative selection	8427780
61465879	61465902	17	-	27260156	PANC0813	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	-0.11053452986781598	[1406]	[1573,1543,1381,1618]	-2	hSpCas9	negative selection	8427781
61478665	61478688	17	-	27260156	RDES	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.28513725552581426	[1096]	[854,973,1119,1239]	-5	hSpCas9	negative selection	8484776
61465909	61465932	17	-	27260156	RDES	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.20039609212434029	[364]	[301,238,385,583]	-3	hSpCas9	negative selection	8484777
61467582	61467605	17	+	27260156	RDES	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.04619831326475987	[40]	[31,31,105,12]	0	hSpCas9	negative selection	8484778
61478632	61478655	17	-	27260156	RDES	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.1284017686372343	[331]	[299,309,381,420]	-2	hSpCas9	negative selection	8549030
61467646	61467669	17	-	27260156	RDES	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.5345280855887663	[308]	[435,519,473,647]	8	hSpCas9	negative selection	8549031
61465879	61465902	17	-	27260156	RDES	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.23084593595813496	[1406]	[1546,1697,2108,2357]	4	hSpCas9	negative selection	8549032
61478665	61478688	17	-	27260156	PC3	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.07314144689394864	[1096]	[656,793,1987,1175]	-2	hSpCas9	negative selection	8606027
61465909	61465932	17	-	27260156	PC3	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.3437557788293033	[364]	[141,216,617,346]	-7	hSpCas9	negative selection	8606028
61467582	61467605	17	+	27260156	PC3	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.49537964349665	[40]	[5,31,39,51]	-8	hSpCas9	negative selection	8606029
61478632	61478655	17	-	27260156	PC3	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.5355603329589597	[331]	[108,174,445,309]	-8	hSpCas9	negative selection	8670281
61467646	61467669	17	-	27260156	PC3	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.09736746940481034	[308]	[125,392,617,358]	2	hSpCas9	negative selection	8670282
61465879	61465902	17	-	27260156	PC3	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.14305219774343003	[1406]	[1019,1280,2848,1646]	3	hSpCas9	negative selection	8670283
61478665	61478688	17	-	27260156	PATU8988T	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.05430995688394247	[1096]	[1282,896,921,1299]	0	hSpCas9	negative selection	8727278
61465909	61465932	17	-	27260156	PATU8988T	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.058016965864906234	[364]	[184,482,383,313]	-1	hSpCas9	negative selection	8727279
61467582	61467605	17	+	27260156	PATU8988T	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.8238063428844291	[40]	[19,62,5,2]	-8	hSpCas9	negative selection	8727280
61478632	61478655	17	-	27260156	PATU8988T	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.17749132738845763	[331]	[316,406,239,173]	-3	hSpCas9	negative selection	8791532
61467646	61467669	17	-	27260156	PATU8988T	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.20715708835514268	[308]	[286,394,270,438]	3	hSpCas9	negative selection	8791533
61465879	61465902	17	-	27260156	PATU8988T	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.3342803687386233	[1406]	[1834,2010,1682,1323]	6	hSpCas9	negative selection	8791534
61478665	61478688	17	-	27260156	T47D	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.03897109067943916	[1096]	[1438,912,1373,1277]	-1	hSpCas9	negative selection	8848529
61465909	61465932	17	-	27260156	T47D	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.057304061258469985	[364]	[452,376,329,480]	-1	hSpCas9	negative selection	8848530
61467582	61467605	17	+	27260156	T47D	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.1484807457330195	[40]	[32,50,43,84]	3	hSpCas9	negative selection	8848531
61478632	61478655	17	-	27260156	T47D	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.06769515944247306	[331]	[380,389,391,308]	-1	hSpCas9	negative selection	8912783
61467646	61467669	17	-	27260156	T47D	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.12242068138078277	[308]	[318,367,438,443]	2	hSpCas9	negative selection	8912784
61465879	61465902	17	-	27260156	T47D	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.1131703441915799	[1406]	[1776,1640,1854,1829]	2	hSpCas9	negative selection	8912785
61478665	61478688	17	-	27260156	SU8686	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.2469103052284085	[1096]	[1229,1057,1472,1461]	4	hSpCas9	negative selection	8969780
61465909	61465932	17	-	27260156	SU8686	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.21350837534593115	[364]	[242,314,239,480]	-4	hSpCas9	negative selection	8969781
61467582	61467605	17	+	27260156	SU8686	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-1.0670751254026798	[40]	[4,22,18,33]	-8	hSpCas9	negative selection	8969782
61478632	61478655	17	-	27260156	SU8686	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.16749868796644485	[331]	[253,292,327,301]	-3	hSpCas9	negative selection	9034034
61467646	61467669	17	-	27260156	SU8686	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.08590611045195606	[308]	[287,334,290,397]	1	hSpCas9	negative selection	9034035
61465879	61465902	17	-	27260156	SU8686	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.03598822764645471	[1406]	[1248,1253,1600,1697]	0	hSpCas9	negative selection	9034036
61478665	61478688	17	-	27260156	SKES1	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.05482083438816443	[1096]	[1211,1057,1004,961]	-1	hSpCas9	negative selection	9091031
61465909	61465932	17	-	27260156	SKES1	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.24989275815083167	[364]	[245,433,363,196]	-5	hSpCas9	negative selection	9091032
61467582	61467605	17	+	27260156	SKES1	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	0.3206273180683006	[40]	[115,67,3,29]	6	hSpCas9	negative selection	9091033
61478632	61478655	17	-	27260156	SKES1	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.06812988356595984	[331]	[444,252,263,309]	-1	hSpCas9	negative selection	9155285
61467646	61467669	17	-	27260156	SKES1	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	-0.11927418712460991	[308]	[274,399,164,303]	-3	hSpCas9	negative selection	9155286
61465879	61465902	17	-	27260156	SKES1	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.06376599385683202	[1406]	[1846,1537,1494,1079]	1	hSpCas9	negative selection	9155287
61478665	61478688	17	-	27260156	TOV112D	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.08495237633003039	[1096]	[1148,1859,1016,812]	1	hSpCas9	negative selection	9212282
61465909	61465932	17	-	27260156	TOV112D	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.24553119064641915	[364]	[261,319,490,162]	-5	hSpCas9	negative selection	9212283
61467582	61467605	17	+	27260156	TOV112D	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.5045302120195525	[40]	[28,57,10,24]	-7	hSpCas9	negative selection	9212284
61478632	61478655	17	-	27260156	TOV112D	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.03410080905174362	[331]	[351,550,221,233]	0	hSpCas9	negative selection	9276536
61467646	61467669	17	-	27260156	TOV112D	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.0746731228273868	[308]	[356,334,362,254]	1	hSpCas9	negative selection	9276537
61465879	61465902	17	-	27260156	TOV112D	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	-0.028863524195204437	[1406]	[1253,2109,1148,1183]	0	hSpCas9	negative selection	9276538
61478665	61478688	17	-	27260156	TC71	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	-0.005704310484434538	[1096]	[1114,1208,1146,1218]	0	hSpCas9	negative selection	9333533
61465909	61465932	17	-	27260156	TC71	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.06890429884384836	[364]	[297,335,443,415]	-2	hSpCas9	negative selection	9333534
61467582	61467605	17	+	27260156	TC71	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.779772542824293	[40]	[20,44,10,25]	-9	hSpCas9	negative selection	9333535
61478632	61478655	17	-	27260156	TC71	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.09388467136098799	[331]	[361,351,323,292]	-2	hSpCas9	negative selection	9397787
61467646	61467669	17	-	27260156	TC71	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.22524589546782997	[308]	[408,384,346,409]	5	hSpCas9	negative selection	9397788
61465879	61465902	17	-	27260156	TC71	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	-0.021958083953161678	[1406]	[1387,1484,1478,1598]	0	hSpCas9	negative selection	9397789
61478665	61478688	17	-	27260156	TC32	viability	TCTCATCAGCCTTAACGATGTGG	TBX4	ENSG00000121075	0.15211640077830735	[1096]	[1087,1094,1295,1076]	2	hSpCas9	negative selection	9454784
61465909	61465932	17	-	27260156	TC32	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.0370584642357602	[364]	[249,418,397,309]	0	hSpCas9	negative selection	9454785
61467582	61467605	17	+	27260156	TC32	viability	AGCCCACTGGATGCGGCAGCTGG	TBX4	ENSG00000121075	-0.025430364612279988	[40]	[20,41,43,43]	0	hSpCas9	negative selection	9454786
61478632	61478655	17	-	27260156	TC32	viability	GGTACTTGTGCATAGAGTTGAGG	TBX4	ENSG00000121075	-0.19519069382437293	[331]	[242,219,284,355]	-4	hSpCas9	negative selection	9519038
61467646	61467669	17	-	27260156	TC32	viability	CCCATGCTTACATGGCCAAAGGG	TBX4	ENSG00000121075	0.5437440588665977	[308]	[308,270,740,479]	8	hSpCas9	negative selection	9519039
61465879	61465902	17	-	27260156	TC32	viability	CAGGGACAATGTCAATCAGCAGG	TBX4	ENSG00000121075	0.08085222861695085	[1406]	[1389,969,1702,1679]	1	hSpCas9	negative selection	9519040
61456508	61456531	17	-	27869803	HPAFII	viability after 27 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.23808021812632474	[105]	[110,27,NaN]	2	hSpCas9	negative selection	9562219
61457536	61457559	17	+	27869803	HPAFII	viability after 27 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.5174000079640534	[148]	[45,61,NaN]	-4	hSpCas9	negative selection	9562220
61465897	61465920	17	-	27869803	HPAFII	viability after 27 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.25724920460907985	[470]	[354,83,NaN]	-2	hSpCas9	negative selection	9562221
61467621	61467644	17	+	27869803	HPAFII	viability after 27 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.20768806499092296	[128]	[49,65,NaN]	-1	hSpCas9	negative selection	9562222
61478653	61478676	17	-	27869803	HPAFII	viability after 27 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.38759833582129444	[121]	[126,47,NaN]	3	hSpCas9	negative selection	9562223
61480147	61480170	17	+	27869803	HPAFII	viability after 27 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	-0.4198529418439405	[510]	[286,128,NaN]	-3	hSpCas9	negative selection	9562224
61456508	61456531	17	-	27869803	HPAFII	viability after 15 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.5830780405543659	[105]	[264,111,NaN]	6	hSpCas9	negative selection	9644668
61457536	61457559	17	+	27869803	HPAFII	viability after 15 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.037675229625021456	[148]	[229,109,NaN]	0	hSpCas9	negative selection	9644669
61465897	61465920	17	-	27869803	HPAFII	viability after 15 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.2548978377269068	[470]	[779,202,NaN]	-3	hSpCas9	negative selection	9644670
61467621	61467644	17	+	27869803	HPAFII	viability after 15 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.2038995475570109	[128]	[128,114,NaN]	-2	hSpCas9	negative selection	9644671
61478653	61478676	17	-	27869803	HPAFII	viability after 15 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.6205441134362022	[121]	[409,71,NaN]	7	hSpCas9	negative selection	9644672
61480147	61480170	17	+	27869803	HPAFII	viability after 15 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	-0.49167479957388516	[510]	[717,186,NaN]	-5	hSpCas9	negative selection	9644673
61456508	61456531	17	-	27869803	ASPC1	viability after 36 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.08522392325829298	[254]	[59,234,5]	0	hSpCas9	negative selection	9727117
61457536	61457559	17	+	27869803	ASPC1	viability after 36 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.7212683859174572	[500]	[195,203,416]	7	hSpCas9	negative selection	9727118
61465897	61465920	17	-	27869803	ASPC1	viability after 36 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	0.22251880619976983	[898]	[302,279,474]	2	hSpCas9	negative selection	9727119
61467621	61467644	17	+	27869803	ASPC1	viability after 36 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	2.060022077904556	[273]	[815,389,108]	9	hSpCas9	negative selection	9727120
61478653	61478676	17	-	27869803	ASPC1	viability after 36 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	1.597176836179348	[175]	[335,37,195]	9	hSpCas9	negative selection	9727121
61480147	61480170	17	+	27869803	ASPC1	viability after 36 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	-0.10976001844830874	[1305]	[644,235,409]	-1	hSpCas9	negative selection	9727122
61456508	61456531	17	-	27869803	PATU8988S	viability after 35 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.1836736667192893	[325]	[202,94,NaN]	2	hSpCas9	negative selection	9809566
61457536	61457559	17	+	27869803	PATU8988S	viability after 35 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.31524439847377406	[404]	[180,224,NaN]	3	hSpCas9	negative selection	9809567
61465897	61465920	17	-	27869803	PATU8988S	viability after 35 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	0.31255238138260855	[676]	[390,285,NaN]	3	hSpCas9	negative selection	9809568
61467621	61467644	17	+	27869803	PATU8988S	viability after 35 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.22093529921699906	[261]	[106,73,NaN]	-2	hSpCas9	negative selection	9809569
61478653	61478676	17	-	27869803	PATU8988S	viability after 35 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	0.29913870943965737	[208]	[133,72,NaN]	3	hSpCas9	negative selection	9809570
61480147	61480170	17	+	27869803	PATU8988S	viability after 35 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	-0.39663103121639565	[1112]	[345,334,NaN]	-4	hSpCas9	negative selection	9809571
61456508	61456531	17	-	27869803	PATU8988S	viability after 31 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.23251593760118905	[325]	[168,131,NaN]	3	hSpCas9	negative selection	9892015
61457536	61457559	17	+	27869803	PATU8988S	viability after 31 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.24625691592094565	[404]	[136,260,NaN]	3	hSpCas9	negative selection	9892016
61465897	61465920	17	-	27869803	PATU8988S	viability after 31 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	0.41439015782763855	[676]	[412,291,NaN]	5	hSpCas9	negative selection	9892017
61467621	61467644	17	+	27869803	PATU8988S	viability after 31 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.07449312115103446	[261]	[142,67,NaN]	0	hSpCas9	negative selection	9892018
61478653	61478676	17	-	27869803	PATU8988S	viability after 31 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	-0.1315016402134912	[208]	[61,93,NaN]	-1	hSpCas9	negative selection	9892019
61480147	61480170	17	+	27869803	PATU8988S	viability after 31 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	-0.5931417130837611	[1112]	[269,324,NaN]	-6	hSpCas9	negative selection	9892020
61456508	61456531	17	-	27869803	HPAFII	viability after 35 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.5648616985654343	[105]	[132,18,NaN]	3	hSpCas9	negative selection	9974464
61457536	61457559	17	+	27869803	HPAFII	viability after 35 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.5512993341857598	[148]	[58,42,NaN]	-3	hSpCas9	negative selection	9974465
61465897	61465920	17	-	27869803	HPAFII	viability after 35 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.13967979118805518	[470]	[270,154,NaN]	-1	hSpCas9	negative selection	9974466
61467621	61467644	17	+	27869803	HPAFII	viability after 35 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.4697049295945215	[128]	[9,88,NaN]	-3	hSpCas9	negative selection	9974467
61478653	61478676	17	-	27869803	HPAFII	viability after 35 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	-0.6116880485735778	[121]	[54,23,NaN]	-4	hSpCas9	negative selection	9974468
61480147	61480170	17	+	27869803	HPAFII	viability after 35 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	-0.651189923874115	[510]	[199,124,NaN]	-4	hSpCas9	negative selection	9974469
61456508	61456531	17	-	27869803	HPAFII	viability after 31 days	AGGCCTCCTCGCTCTCGGACAGG	TBX4	ENSG00000121075	0.7043008284733083	[105]	[139,49,NaN]	5	hSpCas9	negative selection	10056913
61457536	61457559	17	+	27869803	HPAFII	viability after 31 days	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.6611860244842561	[148]	[38,67,NaN]	-4	hSpCas9	negative selection	10056914
61465897	61465920	17	-	27869803	HPAFII	viability after 31 days	TGTAGCGATGGTCATCGGCAGGG	TBX4	ENSG00000121075	-0.21821161129407696	[470]	[276,172,NaN]	-1	hSpCas9	negative selection	10056915
61467621	61467644	17	+	27869803	HPAFII	viability after 31 days	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.08812184949284418	[128]	[36,101,NaN]	0	hSpCas9	negative selection	10056916
61478653	61478676	17	-	27869803	HPAFII	viability after 31 days	TAACGATGTGGAGCCGCGGCTGG	TBX4	ENSG00000121075	-0.5548869684879858	[121]	[48,43,NaN]	-4	hSpCas9	negative selection	10056917
61480147	61480170	17	+	27869803	HPAFII	viability after 31 days	GCTCTCAGCCACACCGGACGTGG	TBX4	ENSG00000121075	-0.3337232192978039	[510]	[306,140,NaN]	-2	hSpCas9	negative selection	10056918
61456505	61456528	17	+	28162770	P31FUJ	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	-0.4999062745572196	[70]	[58]	-4	hSpCas9	negative selection	10248148
61467585	61467608	17	-	28162770	P31FUJ	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	-0.09212054809343306	[741]	[817]	-1	hSpCas9	negative selection	10248149
61457536	61457559	17	+	28162770	P31FUJ	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.0076896327683269065	[214]	[253]	0	hSpCas9	negative selection	10248150
61457575	61457598	17	+	28162770	P31FUJ	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	0.15452836569462342	[275]	[360]	1	hSpCas9	negative selection	10248151
61465909	61465932	17	-	28162770	P31FUJ	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.7145049017454319	[236]	[456]	7	hSpCas9	negative selection	10248152
61467621	61467644	17	+	28162770	P31FUJ	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.30467137052545856	[174]	[253]	3	hSpCas9	negative selection	10248153
61478742	61478765	17	-	28162770	P31FUJ	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-3.144746027749183	[142]	[18]	-9	hSpCas9	negative selection	10248154
61480260	61480283	17	+	28162770	P31FUJ	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.16223227021684128	[1161]	[1527]	1	hSpCas9	negative selection	10248155
61456663	61456686	17	-	28162770	P31FUJ	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.12083475020032186	[143]	[183]	1	hSpCas9	negative selection	10248156
61457606	61457629	17	+	28162770	P31FUJ	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	-1.849473564862873	[91]	[29]	-8	hSpCas9	negative selection	10248157
61456505	61456528	17	+	28162770	TF1	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10417514
61467585	61467608	17	-	28162770	TF1	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	NaN	[NaN]	[780]	1	hSpCas9	negative selection	10417515
61457536	61457559	17	+	28162770	TF1	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10417516
61457575	61457598	17	+	28162770	TF1	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10417517
61465909	61465932	17	-	28162770	TF1	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	NaN	[NaN]	[441]	1	hSpCas9	negative selection	10417518
61467621	61467644	17	+	28162770	TF1	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	NaN	[NaN]	[99]	1	hSpCas9	negative selection	10417519
61478742	61478765	17	-	28162770	TF1	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10417520
61480260	61480283	17	+	28162770	TF1	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	NaN	[NaN]	[869]	1	hSpCas9	negative selection	10417521
61456663	61456686	17	-	28162770	TF1	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	NaN	[NaN]	[194]	1	hSpCas9	negative selection	10417522
61457606	61457629	17	+	28162770	TF1	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10417523
61456505	61456528	17	+	28162770	SKM1	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	-0.06016143521677009	[22]	[38]	0	hSpCas9	negative selection	10586880
61467585	61467608	17	-	28162770	SKM1	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	0.09226842795211065	[155]	[293]	0	hSpCas9	negative selection	10586881
61457536	61457559	17	+	28162770	SKM1	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.45101679638441056	[59]	[144]	4	hSpCas9	negative selection	10586882
61457575	61457598	17	+	28162770	SKM1	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.6293566200796097	[69]	[79]	-5	hSpCas9	negative selection	10586883
61465909	61465932	17	-	28162770	SKM1	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.18922555740124863	[63]	[128]	1	hSpCas9	negative selection	10586884
61467621	61467644	17	+	28162770	SKM1	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.7499046498737044	[36]	[109]	7	hSpCas9	negative selection	10586885
61478742	61478765	17	-	28162770	SKM1	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-1.4069641987431614	[23]	[15]	-7	hSpCas9	negative selection	10586886
61480260	61480283	17	+	28162770	SKM1	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.25671027799203494	[213]	[451]	2	hSpCas9	negative selection	10586887
61456663	61456686	17	-	28162770	SKM1	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	-0.1495763560505099	[31]	[50]	-1	hSpCas9	negative selection	10586888
61457606	61457629	17	+	28162770	SKM1	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	0.8218544917527193	[15]	[49]	7	hSpCas9	negative selection	10586889
61456505	61456528	17	+	28162770	SKM1	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	-0.06016143521677009	[22]	[38]	0	hSpCas9	negative selection	10756246
61467585	61467608	17	-	28162770	SKM1	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	0.09226842795211065	[155]	[293]	0	hSpCas9	negative selection	10756247
61457536	61457559	17	+	28162770	SKM1	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.45101679638441056	[59]	[144]	4	hSpCas9	negative selection	10756248
61457575	61457598	17	+	28162770	SKM1	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.6293566200796097	[69]	[79]	-5	hSpCas9	negative selection	10756249
61465909	61465932	17	-	28162770	SKM1	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.18922555740124863	[63]	[128]	1	hSpCas9	negative selection	10756250
61467621	61467644	17	+	28162770	SKM1	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.7499046498737044	[36]	[109]	7	hSpCas9	negative selection	10756251
61478742	61478765	17	-	28162770	SKM1	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-1.4069641987431614	[23]	[15]	-7	hSpCas9	negative selection	10756252
61480260	61480283	17	+	28162770	SKM1	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.25671027799203494	[213]	[451]	2	hSpCas9	negative selection	10756253
61456663	61456686	17	-	28162770	SKM1	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	-0.1495763560505099	[31]	[50]	-1	hSpCas9	negative selection	10756254
61457606	61457629	17	+	28162770	SKM1	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	0.8218544917527193	[15]	[49]	7	hSpCas9	negative selection	10756255
61456505	61456528	17	+	28162770	PL21	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	0.0781490901107098	[73]	[33]	0	hSpCas9	negative selection	10925612
61467585	61467608	17	-	28162770	PL21	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	-0.13243572459755049	[543]	[215]	-1	hSpCas9	negative selection	10925613
61457536	61457559	17	+	28162770	PL21	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.2578551123456073	[195]	[101]	2	hSpCas9	negative selection	10925614
61457575	61457598	17	+	28162770	PL21	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	0.09913629580584427	[280]	[130]	0	hSpCas9	negative selection	10925615
61465909	61465932	17	-	28162770	PL21	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.7079342546880163	[255]	[181]	6	hSpCas9	negative selection	10925616
61467621	61467644	17	+	28162770	PL21	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.3568085100622395	[152]	[51]	-3	hSpCas9	negative selection	10925617
61478742	61478765	17	-	28162770	PL21	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-0.9403416090605102	[96]	[21]	-6	hSpCas9	negative selection	10925618
61480260	61480283	17	+	28162770	PL21	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.5385901652893448	[763]	[482]	5	hSpCas9	negative selection	10925619
61456663	61456686	17	-	28162770	PL21	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.9458224257566352	[98]	[82]	7	hSpCas9	negative selection	10925620
61457606	61457629	17	+	28162770	PL21	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	1.3403172725375803	[48]	[53]	9	hSpCas9	negative selection	10925621
61456505	61456528	17	+	28162770	P31FUJ	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	-0.4999062745572196	[70]	[58]	-4	hSpCas9	negative selection	11094978
61467585	61467608	17	-	28162770	P31FUJ	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	-0.09212054809343306	[741]	[817]	-1	hSpCas9	negative selection	11094979
61457536	61457559	17	+	28162770	P31FUJ	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.0076896327683269065	[214]	[253]	0	hSpCas9	negative selection	11094980
61457575	61457598	17	+	28162770	P31FUJ	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	0.15452836569462342	[275]	[360]	1	hSpCas9	negative selection	11094981
61465909	61465932	17	-	28162770	P31FUJ	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.7145049017454319	[236]	[456]	7	hSpCas9	negative selection	11094982
61467621	61467644	17	+	28162770	P31FUJ	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.30467137052545856	[174]	[253]	3	hSpCas9	negative selection	11094983
61478742	61478765	17	-	28162770	P31FUJ	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-3.144746027749183	[142]	[18]	-9	hSpCas9	negative selection	11094984
61480260	61480283	17	+	28162770	P31FUJ	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.16223227021684128	[1161]	[1527]	1	hSpCas9	negative selection	11094985
61456663	61456686	17	-	28162770	P31FUJ	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.12083475020032186	[143]	[183]	1	hSpCas9	negative selection	11094986
61457606	61457629	17	+	28162770	P31FUJ	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	-1.849473564862873	[91]	[29]	-8	hSpCas9	negative selection	11094987
61456505	61456528	17	+	28162770	OCIAML5	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	-1.357301879114419	[43]	[30]	-7	hSpCas9	negative selection	11264344
61467585	61467608	17	-	28162770	OCIAML5	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	0.20428428351736683	[476]	[991]	1	hSpCas9	negative selection	11264345
61457536	61457559	17	+	28162770	OCIAML5	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.1905777665444967	[99]	[205]	1	hSpCas9	negative selection	11264346
61457575	61457598	17	+	28162770	OCIAML5	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-1.4544111498133896	[166]	[109]	-7	hSpCas9	negative selection	11264347
61465909	61465932	17	-	28162770	OCIAML5	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.6813656292170771	[132]	[384]	6	hSpCas9	negative selection	11264348
61467621	61467644	17	+	28162770	OCIAML5	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.8789374650634924	[96]	[321]	7	hSpCas9	negative selection	11264349
61478742	61478765	17	-	28162770	OCIAML5	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-1.5183291736870013	[72]	[45]	-7	hSpCas9	negative selection	11264350
61480260	61480283	17	+	28162770	OCIAML5	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.6217349311866174	[444]	[1235]	5	hSpCas9	negative selection	11264351
61456663	61456686	17	-	28162770	OCIAML5	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.35497788613901504	[80]	[186]	3	hSpCas9	negative selection	11264352
61457606	61457629	17	+	28162770	OCIAML5	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	0.8809945688462931	[36]	[122]	7	hSpCas9	negative selection	11264353
61456505	61456528	17	+	28162770	EOL1	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	0.5884985684385196	[153]	[121]	5	hSpCas9	negative selection	11433710
61467585	61467608	17	-	28162770	EOL1	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	0.2629639892464657	[695]	[439]	2	hSpCas9	negative selection	11433711
61457536	61457559	17	+	28162770	EOL1	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.17265563316622567	[420]	[249]	1	hSpCas9	negative selection	11433712
61457575	61457598	17	+	28162770	EOL1	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.3237814389495399	[448]	[188]	-2	hSpCas9	negative selection	11433713
61465909	61465932	17	-	28162770	EOL1	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	1.130796151312751	[474]	[547]	8	hSpCas9	negative selection	11433714
61467621	61467644	17	+	28162770	EOL1	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.7990168894866755	[299]	[274]	7	hSpCas9	negative selection	11433715
61478742	61478765	17	-	28162770	EOL1	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-1.7582620525487662	[121]	[18]	-8	hSpCas9	negative selection	11433716
61480260	61480283	17	+	28162770	EOL1	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.2706673301746485	[1028]	[653]	2	hSpCas9	negative selection	11433717
61456663	61456686	17	-	28162770	EOL1	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.4342221449874535	[117]	[83]	4	hSpCas9	negative selection	11433718
61457606	61457629	17	+	28162770	EOL1	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	-2.4677696512082257	[83]	[7]	-8	hSpCas9	negative selection	11433719
61456505	61456528	17	+	28162770	MOLM13	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	1.0702339604939715	[109]	[166]	7	hSpCas9	negative selection	11603076
61467585	61467608	17	-	28162770	MOLM13	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	-0.35373210958607393	[812]	[459]	-2	hSpCas9	negative selection	11603077
61457536	61457559	17	+	28162770	MOLM13	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.03383991373993167	[330]	[244]	0	hSpCas9	negative selection	11603078
61457575	61457598	17	+	28162770	MOLM13	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.2330569898206455	[355]	[218]	-1	hSpCas9	negative selection	11603079
61465909	61465932	17	-	28162770	MOLM13	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	1.2013744069758232	[414]	[689]	8	hSpCas9	negative selection	11603080
61467621	61467644	17	+	28162770	MOLM13	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.018904550342397422	[257]	[188]	0	hSpCas9	negative selection	11603081
61478742	61478765	17	-	28162770	MOLM13	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-7.007844049421819	[177]	[0]	-9	hSpCas9	negative selection	11603082
61480260	61480283	17	+	28162770	MOLM13	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	-0.29246806097585587	[1056]	[623]	-2	hSpCas9	negative selection	11603083
61456663	61456686	17	-	28162770	MOLM13	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.7609363564448123	[110]	[135]	6	hSpCas9	negative selection	11603084
61457606	61457629	17	+	28162770	MOLM13	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	-0.48838924102610326	[129]	[66]	-3	hSpCas9	negative selection	11603085
61456505	61456528	17	+	28162770	HEL	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	0.9809075678949303	[105]	[133]	8	hSpCas9	negative selection	11772442
61467585	61467608	17	-	28162770	HEL	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	-0.03490054573956414	[666]	[416]	0	hSpCas9	negative selection	11772443
61457536	61457559	17	+	28162770	HEL	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.24603315549377025	[390]	[296]	2	hSpCas9	negative selection	11772444
61457575	61457598	17	+	28162770	HEL	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-1.254607990937291	[338]	[90]	-6	hSpCas9	negative selection	11772445
61465909	61465932	17	-	28162770	HEL	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.29251274271062966	[398]	[312]	2	hSpCas9	negative selection	11772446
61467621	61467644	17	+	28162770	HEL	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.7670669670025586	[199]	[217]	6	hSpCas9	negative selection	11772447
61478742	61478765	17	-	28162770	HEL	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-0.5880413748288102	[114]	[48]	-4	hSpCas9	negative selection	11772448
61480260	61480283	17	+	28162770	HEL	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	-0.2950011088382929	[838]	[437]	-2	hSpCas9	negative selection	11772449
61456663	61456686	17	-	28162770	HEL	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.40629863617827633	[85]	[72]	3	hSpCas9	negative selection	11772450
61457606	61457629	17	+	28162770	HEL	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	-1.1202219706987937	[111]	[32]	-6	hSpCas9	negative selection	11772451
61456505	61456528	17	+	28162770	MV411	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	0.3652740410766335	[46]	[50]	3	hSpCas9	negative selection	11941808
61467585	61467608	17	-	28162770	MV411	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	0.25081227756343183	[426]	[427]	2	hSpCas9	negative selection	11941809
61457536	61457559	17	+	28162770	MV411	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.28383707904439276	[210]	[145]	-2	hSpCas9	negative selection	11941810
61457575	61457598	17	+	28162770	MV411	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.775105017868313	[257]	[126]	-5	hSpCas9	negative selection	11941811
61465909	61465932	17	-	28162770	MV411	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.5832600873285185	[247]	[312]	5	hSpCas9	negative selection	11941812
61467621	61467644	17	+	28162770	MV411	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.6285277181382816	[128]	[167]	5	hSpCas9	negative selection	11941813
61478742	61478765	17	-	28162770	MV411	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-1.8796743671205642	[82]	[18]	-8	hSpCas9	negative selection	11941814
61480260	61480283	17	+	28162770	MV411	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.3315646794698588	[865]	[917]	3	hSpCas9	negative selection	11941815
61456663	61456686	17	-	28162770	MV411	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	-0.03267036840996007	[67]	[55]	0	hSpCas9	negative selection	11941816
61457606	61457629	17	+	28162770	MV411	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	0.24743755078277507	[48]	[48]	2	hSpCas9	negative selection	11941817
61456505	61456528	17	+	28162770	MONOMAC1	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	0.6509600594953961	[29]	[53]	6	hSpCas9	negative selection	12111174
61467585	61467608	17	-	28162770	MONOMAC1	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	0.31084943064296167	[345]	[491]	3	hSpCas9	negative selection	12111175
61457536	61457559	17	+	28162770	MONOMAC1	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	0.031232140613563636	[104]	[122]	0	hSpCas9	negative selection	12111176
61457575	61457598	17	+	28162770	MONOMAC1	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-1.5833153533569737	[148]	[56]	-8	hSpCas9	negative selection	12111177
61465909	61465932	17	-	28162770	MONOMAC1	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.4928126540909475	[204]	[166]	-4	hSpCas9	negative selection	12111178
61467621	61467644	17	+	28162770	MONOMAC1	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	-0.8391432548843185	[102]	[65]	-6	hSpCas9	negative selection	12111179
61478742	61478765	17	-	28162770	MONOMAC1	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-1.315218273407868	[88]	[40]	-7	hSpCas9	negative selection	12111180
61480260	61480283	17	+	28162770	MONOMAC1	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.13553849202731705	[512]	[645]	1	hSpCas9	negative selection	12111181
61456663	61456686	17	-	28162770	MONOMAC1	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.030373649043518913	[40]	[47]	0	hSpCas9	negative selection	12111182
61457606	61457629	17	+	28162770	MONOMAC1	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	0.9333597901961213	[36]	[80]	8	hSpCas9	negative selection	12111183
61456505	61456528	17	+	28162770	OCIAML2	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	-0.11307782062407745	[15]	[81]	-1	hSpCas9	negative selection	12280540
61467585	61467608	17	-	28162770	OCIAML2	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	0.014797001928080533	[94]	[531]	0	hSpCas9	negative selection	12280541
61457536	61457559	17	+	28162770	OCIAML2	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.8953174945547242	[49]	[148]	-6	hSpCas9	negative selection	12280542
61457575	61457598	17	+	28162770	OCIAML2	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-0.6851343371482963	[37]	[130]	-5	hSpCas9	negative selection	12280543
61465909	61465932	17	-	28162770	OCIAML2	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	0.298364623116683	[48]	[333]	3	hSpCas9	negative selection	12280544
61467621	61467644	17	+	28162770	OCIAML2	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.13817941743336276	[29]	[182]	1	hSpCas9	negative selection	12280545
61478742	61478765	17	-	28162770	OCIAML2	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	-2.9067289400488345	[22]	[16]	-9	hSpCas9	negative selection	12280546
61480260	61480283	17	+	28162770	OCIAML2	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.23403943284087925	[130]	[853]	2	hSpCas9	negative selection	12280547
61456663	61456686	17	-	28162770	OCIAML2	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	0.33672509681544305	[17]	[125]	3	hSpCas9	negative selection	12280548
61457606	61457629	17	+	28162770	OCIAML2	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	-0.12270652182185438	[10]	[55]	-1	hSpCas9	negative selection	12280549
61456505	61456528	17	+	28162770	OCIAML3	viability	GGGCCTGTCCGAGAGCGAGGAGG	TBX4	ENSG00000121075	-0.9159357352115254	[19]	[31]	-6	hSpCas9	negative selection	12449906
61467585	61467608	17	-	28162770	OCIAML3	viability	AGACCAGCTGCCGCATCCAGTGG	TBX4	ENSG00000121075	-0.2599389825645888	[141]	[357]	-2	hSpCas9	negative selection	12449907
61457536	61457559	17	+	28162770	OCIAML3	viability	GACCATCGAGAACATCAAGGTGG	TBX4	ENSG00000121075	-0.017360407815010567	[57]	[172]	0	hSpCas9	negative selection	12449908
61457575	61457598	17	+	28162770	OCIAML3	viability	GCTCTGGAAGAAGTTCCACGAGG	TBX4	ENSG00000121075	-1.2121370049805187	[65]	[85]	-7	hSpCas9	negative selection	12449909
61465909	61465932	17	-	28162770	OCIAML3	viability	TGTCACAGAACTTGTAGCGATGG	TBX4	ENSG00000121075	-0.05591174464098114	[72]	[211]	0	hSpCas9	negative selection	12449910
61467621	61467644	17	+	28162770	OCIAML3	viability	GAAGCTGACAAACAACCACCTGG	TBX4	ENSG00000121075	0.14745934607698374	[31]	[106]	1	hSpCas9	negative selection	12449911
61478742	61478765	17	-	28162770	OCIAML3	viability	GGAGGTCACAGAGATGAAGGAGG	TBX4	ENSG00000121075	0.34459181501169334	[23]	[91]	3	hSpCas9	negative selection	12449912
61480260	61480283	17	+	28162770	OCIAML3	viability	TCAGCACCTTTCCCACCCAGAGG	TBX4	ENSG00000121075	0.5643177405122186	[221]	[990]	5	hSpCas9	negative selection	12449913
61456663	61456686	17	-	28162770	OCIAML3	viability	CAGCCCTACCTGCTCCGCGGCGG	TBX4	ENSG00000121075	-0.9601355391220605	[28]	[44]	-6	hSpCas9	negative selection	12449914
61457606	61457629	17	+	28162770	OCIAML3	viability	GAGATGATCATCACTAAGGCTGG	TBX4	ENSG00000121075	-0.8570420461579571	[14]	[24]	-6	hSpCas9	negative selection	12449915