Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:63892
• Symbol:THADA
• Description:THADA armadillo repeat containing

DataSource: http://genomecrispr.dkfz.de/#!/results/THADA

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
43577149	43577172	2	+	26472758	Jiyoye	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	0.8653807399410909	[106]	[146]	6	hSpCas9	negative selection	164934
43574796	43574819	2	-	26472758	Jiyoye	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	4.86660700014317	[0]	[21]	9	hSpCas9	negative selection	164935
43577083	43577106	2	-	26472758	Jiyoye	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	-0.11111607956999514	[221]	[154]	-1	hSpCas9	negative selection	164936
43574499	43574522	2	-	26472758	Jiyoye	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	3.0080794260960513	[14]	[90]	9	hSpCas9	negative selection	164937
43551835	43551858	2	+	26472758	Jiyoye	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	1.1441409756720793	[113]	[189]	7	hSpCas9	negative selection	164938
43428152	43428175	2	-	26472758	Jiyoye	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	1.1727101278688505	[39]	[67]	7	hSpCas9	negative selection	164939
43292123	43292146	2	-	26472758	Jiyoye	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	2.48117596294965	[18]	[79]	9	hSpCas9	negative selection	164940
43287026	43287049	2	-	26472758	Jiyoye	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	0.9072489846405165	[69]	[98]	6	hSpCas9	negative selection	164941
43286948	43286971	2	+	26472758	Jiyoye	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	2.599820459448269	[13]	[63]	9	hSpCas9	negative selection	164942
43591980	43592003	2	-	26472758	Jiyoye	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.9690542691139884	[62]	[92]	6	hSpCas9	negative selection	164943
43577149	43577172	2	+	26472758	KBM7	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	-0.4605165958623319	[520,575]	[145,227]	-4	hSpCas9	negative selection	356052
43574796	43574819	2	-	26472758	KBM7	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	-0.6229276860604895	[142,111]	[54,23]	-5	hSpCas9	negative selection	356053
43577083	43577106	2	-	26472758	KBM7	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.7555789260424527	[868,774]	[606,691]	8	hSpCas9	negative selection	356054
43574499	43574522	2	-	26472758	KBM7	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	-0.8904067657421572	[505,274]	[76,113]	-6	hSpCas9	negative selection	356055
43551835	43551858	2	+	26472758	KBM7	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.24407994473401362	[797,488]	[496,220]	2	hSpCas9	negative selection	356056
43428152	43428175	2	-	26472758	KBM7	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	0.06426794160659477	[363,239]	[106,180]	0	hSpCas9	negative selection	356057
43292123	43292146	2	-	26472758	KBM7	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	0.01903481276727015	[392,393]	[123,245]	0	hSpCas9	negative selection	356058
43287026	43287049	2	-	26472758	KBM7	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	0.20518835960690837	[534,413]	[290,222]	2	hSpCas9	negative selection	356059
43286948	43286971	2	+	26472758	KBM7	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	0.27328379835032457	[362,325]	[277,121]	3	hSpCas9	negative selection	356060
43591980	43592003	2	-	26472758	KBM7	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.7908554529515817	[374,264]	[256,256]	8	hSpCas9	negative selection	356061
43577149	43577172	2	+	26472758	Raji	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	-0.1921767464853083	[191]	[38]	-2	hSpCas9	negative selection	547170
43574796	43574819	2	-	26472758	Raji	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	-0.6295820587926069	[19]	[2]	-5	hSpCas9	negative selection	547171
43577083	43577106	2	-	26472758	Raji	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.8723635057094021	[305]	[129]	7	hSpCas9	negative selection	547172
43574499	43574522	2	-	26472758	Raji	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	0.8388946994476975	[158]	[65]	7	hSpCas9	negative selection	547173
43551835	43551858	2	+	26472758	Raji	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.6247196104985852	[312]	[111]	6	hSpCas9	negative selection	547174
43428152	43428175	2	-	26472758	Raji	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	-2.0053165973757627	[172]	[9]	-8	hSpCas9	negative selection	547175
43292123	43292146	2	-	26472758	Raji	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	-0.49112549718550436	[320]	[52]	-4	hSpCas9	negative selection	547176
43287026	43287049	2	-	26472758	Raji	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	-0.06920519634972377	[216]	[47]	0	hSpCas9	negative selection	547177
43286948	43286971	2	+	26472758	Raji	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	0.6846924635513204	[125]	[46]	6	hSpCas9	negative selection	547178
43591980	43592003	2	-	26472758	Raji	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.6093566714237242	[160]	[56]	6	hSpCas9	negative selection	547179
43577149	43577172	2	+	26472758	K562	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	0.12977616172532402	[575]	[531]	0	hSpCas9	negative selection	738288
43574796	43574819	2	-	26472758	K562	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	-0.029342084760405562	[80]	[66]	0	hSpCas9	negative selection	738289
43577083	43577106	2	-	26472758	K562	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.45424038947311274	[740]	[856]	3	hSpCas9	negative selection	738290
43574499	43574522	2	-	26472758	K562	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	0.05578671223067436	[358]	[314]	0	hSpCas9	negative selection	738291
43551835	43551858	2	+	26472758	K562	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.683248723067053	[435]	[590]	5	hSpCas9	negative selection	738292
43428152	43428175	2	-	26472758	K562	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	0.5839051939381138	[146]	[185]	5	hSpCas9	negative selection	738293
43292123	43292146	2	-	26472758	K562	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	-0.6896359605097004	[448]	[234]	-4	hSpCas9	negative selection	738294
43287026	43287049	2	-	26472758	K562	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	0.03796785019902049	[449]	[389]	0	hSpCas9	negative selection	738295
43286948	43286971	2	+	26472758	K562	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	0.6146019911610303	[293]	[379]	5	hSpCas9	negative selection	738296
43591980	43592003	2	-	26472758	K562	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.276695130690203	[220]	[225]	2	hSpCas9	negative selection	738297
43498907	43498930	2	-	26627737	DLD1	viability	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-1.0478133310915925	[322]	[52,30,59]	-7	hSpCas9	negative selection	811993
43541278	43541301	2	-	26627737	DLD1	viability	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	-0.06647124876875246	[497]	[90,239,122]	0	hSpCas9	negative selection	811994
43551835	43551858	2	+	26627737	DLD1	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.6191119506096698	[512]	[122,111,81]	-6	hSpCas9	negative selection	811995
43556358	43556381	2	-	26627737	DLD1	viability	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.45159851602714285	[816]	[444,351,263]	4	hSpCas9	negative selection	811996
43574836	43574859	2	+	26627737	DLD1	viability	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-1.1364205938251852	[221]	[12,6,67]	-7	hSpCas9	negative selection	811997
43592327	43592350	2	+	26627737	DLD1	viability	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.5001331301017236	[908]	[372,501,343]	5	hSpCas9	negative selection	811998
43498907	43498930	2	-	26627737	GBM cells	viability after 5 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-0.36412053094810815	[77]	[38,25]	-5	hSpCas9	negative selection	894308
43541278	43541301	2	-	26627737	GBM cells	viability after 5 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	0.3660398853129835	[169]	[98,135]	5	hSpCas9	negative selection	894309
43551835	43551858	2	+	26627737	GBM cells	viability after 5 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.1895549129766285	[268]	[141,110]	-3	hSpCas9	negative selection	894310
43556358	43556381	2	-	26627737	GBM cells	viability after 5 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	-0.05046005204434645	[475]	[244,247]	-1	hSpCas9	negative selection	894311
43574836	43574859	2	+	26627737	GBM cells	viability after 5 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	0.32842185697286275	[123]	[95,70]	5	hSpCas9	negative selection	894312
43592327	43592350	2	+	26627737	GBM cells	viability after 5 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.559969802982722	[596]	[448,494]	7	hSpCas9	negative selection	894313
43498907	43498930	2	-	26627737	GBM cells	viability after 13 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-0.2169663373198758	[77]	[31,39]	-3	hSpCas9	negative selection	976623
43541278	43541301	2	-	26627737	GBM cells	viability after 13 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	0.6775709789924451	[169]	[173,125]	7	hSpCas9	negative selection	976624
43551835	43551858	2	+	26627737	GBM cells	viability after 13 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.46364213721392555	[268]	[128,86]	-5	hSpCas9	negative selection	976625
43556358	43556381	2	-	26627737	GBM cells	viability after 13 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.3824729401718292	[475]	[366,311]	5	hSpCas9	negative selection	976626
43574836	43574859	2	+	26627737	GBM cells	viability after 13 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	0.09237012943762146	[123]	[79,64]	1	hSpCas9	negative selection	976627
43592327	43592350	2	+	26627737	GBM cells	viability after 13 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.6947080850184408	[596]	[531,517]	8	hSpCas9	negative selection	976628
43498907	43498930	2	-	26627737	GBM cells	viability after 21 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-0.1442232571407489	[77]	[41,34]	-1	hSpCas9	negative selection	1058938
43541278	43541301	2	-	26627737	GBM cells	viability after 21 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	-0.02842638884591564	[169]	[100,80]	0	hSpCas9	negative selection	1058939
43551835	43551858	2	+	26627737	GBM cells	viability after 21 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.1980075955720276	[268]	[117,135]	-2	hSpCas9	negative selection	1058940
43556358	43556381	2	-	26627737	GBM cells	viability after 21 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.12382956500480957	[475]	[286,276]	1	hSpCas9	negative selection	1058941
43574836	43574859	2	+	26627737	GBM cells	viability after 21 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	0.516831935252094	[123]	[98,93]	5	hSpCas9	negative selection	1058942
43592327	43592350	2	+	26627737	GBM cells	viability after 21 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.7543362233929984	[596]	[567,527]	7	hSpCas9	negative selection	1058943
43498907	43498930	2	-	26627737	RPE1	viability after 9 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-0.06001973493853141	[297]	[85,93]	0	hSpCas9	negative selection	1141253
43541278	43541301	2	-	26627737	RPE1	viability after 9 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	1.7295651344192233	[422]	[398,490]	8	hSpCas9	negative selection	1141254
43551835	43551858	2	+	26627737	RPE1	viability after 9 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.12316593725168973	[598]	[138,214]	-1	hSpCas9	negative selection	1141255
43556358	43556381	2	-	26627737	RPE1	viability after 9 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	-0.3540669741843545	[2736]	[741,577]	-3	hSpCas9	negative selection	1141256
43574836	43574859	2	+	26627737	RPE1	viability after 9 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.2890857167229546	[510]	[64,215]	-2	hSpCas9	negative selection	1141257
43592327	43592350	2	+	26627737	RPE1	viability after 9 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.3666528739418342	[2356]	[664,1320]	2	hSpCas9	negative selection	1141258
43498907	43498930	2	-	26627737	RPE1	viability after 12 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.4356420073244638	[297]	[83,133]	3	hSpCas9	negative selection	1223568
43541278	43541301	2	-	26627737	RPE1	viability after 12 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	0.7178305856910001	[422]	[166,207]	4	hSpCas9	negative selection	1223569
43551835	43551858	2	+	26627737	RPE1	viability after 12 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.02886991226867519	[598]	[131,184]	0	hSpCas9	negative selection	1223570
43556358	43556381	2	-	26627737	RPE1	viability after 12 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	-0.18356375547545611	[2736]	[646,647]	-1	hSpCas9	negative selection	1223571
43574836	43574859	2	+	26627737	RPE1	viability after 12 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.12313401061806739	[510]	[93,159]	-1	hSpCas9	negative selection	1223572
43592327	43592350	2	+	26627737	RPE1	viability after 12 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.4521696459784561	[2356]	[673,1069]	3	hSpCas9	negative selection	1223573
43498907	43498930	2	-	26627737	RPE1	viability after 15 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.5800675011330578	[297]	[124,126]	3	hSpCas9	negative selection	1305883
43541278	43541301	2	-	26627737	RPE1	viability after 15 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	1.3098937035505878	[422]	[343,250]	7	hSpCas9	negative selection	1305884
43551835	43551858	2	+	26627737	RPE1	viability after 15 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.5103643261299657	[598]	[164,314]	3	hSpCas9	negative selection	1305885
43556358	43556381	2	-	26627737	RPE1	viability after 15 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	-0.34147941287601813	[2736]	[804,423]	-2	hSpCas9	negative selection	1305886
43574836	43574859	2	+	26627737	RPE1	viability after 15 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	0.10741672304490801	[510]	[114,194]	0	hSpCas9	negative selection	1305887
43592327	43592350	2	+	26627737	RPE1	viability after 15 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.1841149089820402	[2356]	[644,865]	1	hSpCas9	negative selection	1305888
43498907	43498930	2	-	26627737	RPE1	viability after 18 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.1493028989632874	[297]	[50,129]	1	hSpCas9	negative selection	1388198
43541278	43541301	2	-	26627737	RPE1	viability after 18 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	1.0662214601467384	[422]	[239,237]	6	hSpCas9	negative selection	1388199
43551835	43551858	2	+	26627737	RPE1	viability after 18 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.5106474504910217	[598]	[209,251]	3	hSpCas9	negative selection	1388200
43556358	43556381	2	-	26627737	RPE1	viability after 18 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	-0.38745176440305884	[2736]	[656,465]	-2	hSpCas9	negative selection	1388201
43574836	43574859	2	+	26627737	RPE1	viability after 18 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.4539105077557627	[510]	[32,172]	-3	hSpCas9	negative selection	1388202
43592327	43592350	2	+	26627737	RPE1	viability after 18 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	-0.000786990254481923	[2356]	[525,752]	0	hSpCas9	negative selection	1388203
43498907	43498930	2	-	26627737	HeLa	viability after 8 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.4917030034020764	[132]	[92,76,76]	4	hSpCas9	negative selection	1470513
43541278	43541301	2	-	26627737	HeLa	viability after 8 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	-1.320133724287233	[717]	[24,212,115]	-8	hSpCas9	negative selection	1470514
43551835	43551858	2	+	26627737	HeLa	viability after 8 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.5368405270255574	[271]	[210,173,140]	5	hSpCas9	negative selection	1470515
43556358	43556381	2	-	26627737	HeLa	viability after 8 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	1.1022148477504665	[417]	[535,358,313]	8	hSpCas9	negative selection	1470516
43574836	43574859	2	+	26627737	HeLa	viability after 8 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-1.1972239856061726	[392]	[58,96,64]	-8	hSpCas9	negative selection	1470517
43592327	43592350	2	+	26627737	HeLa	viability after 8 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.17279363042472973	[795]	[606,295,320]	1	hSpCas9	negative selection	1470518
43498907	43498930	2	-	26627737	HeLa	viability after 12 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.36538843846326285	[132]	[162,33,21]	3	hSpCas9	negative selection	1552828
43541278	43541301	2	-	26627737	HeLa	viability after 12 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	-1.027951412758076	[717]	[27,259,132]	-7	hSpCas9	negative selection	1552829
43551835	43551858	2	+	26627737	HeLa	viability after 12 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.20319885976865693	[271]	[168,132,86]	1	hSpCas9	negative selection	1552830
43556358	43556381	2	-	26627737	HeLa	viability after 12 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	1.2984582316950823	[417]	[707,357,223]	8	hSpCas9	negative selection	1552831
43574836	43574859	2	+	26627737	HeLa	viability after 12 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.5697363946918144	[392]	[69,204,41]	-5	hSpCas9	negative selection	1552832
43592327	43592350	2	+	26627737	HeLa	viability after 12 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.23477831440455144	[795]	[506,299,366]	2	hSpCas9	negative selection	1552833
43498907	43498930	2	-	26627737	HeLa	viability after 15 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.9297058458143211	[132]	[116,91,99]	7	hSpCas9	negative selection	1635143
43541278	43541301	2	-	26627737	HeLa	viability after 15 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	-0.9814806942077554	[717]	[163,166,109]	-7	hSpCas9	negative selection	1635144
43551835	43551858	2	+	26627737	HeLa	viability after 15 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.46801472077555156	[271]	[144,216,92]	4	hSpCas9	negative selection	1635145
43556358	43556381	2	-	26627737	HeLa	viability after 15 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	1.6042426532502931	[417]	[674,539,319]	9	hSpCas9	negative selection	1635146
43574836	43574859	2	+	26627737	HeLa	viability after 15 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-1.4755429806920213	[392]	[40,71,59]	-8	hSpCas9	negative selection	1635147
43592327	43592350	2	+	26627737	HeLa	viability after 15 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	-0.09136626187361718	[795]	[344,334,225]	-1	hSpCas9	negative selection	1635148
43498907	43498930	2	-	26627737	HeLa	viability after 18 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.9105523317240259	[132]	[79,70,99]	7	hSpCas9	negative selection	1717458
43541278	43541301	2	-	26627737	HeLa	viability after 18 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	-0.9530198730124193	[717]	[115,137,109]	-7	hSpCas9	negative selection	1717459
43551835	43551858	2	+	26627737	HeLa	viability after 18 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.4937604664551001	[271]	[103,177,92]	4	hSpCas9	negative selection	1717460
43556358	43556381	2	-	26627737	HeLa	viability after 18 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	1.5961775689484081	[417]	[448,444,319]	8	hSpCas9	negative selection	1717461
43574836	43574859	2	+	26627737	HeLa	viability after 18 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-1.4781745527653205	[392]	[26,59,59]	-8	hSpCas9	negative selection	1717462
43592327	43592350	2	+	26627737	HeLa	viability after 18 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	-0.10163109708745088	[795]	[233,268,225]	-1	hSpCas9	negative selection	1717463
43498907	43498930	2	-	26627737	HCT116	viability after 6 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.436860977921799	[284]	[166,1]	2	hSpCas9	negative selection	1799773
43541278	43541301	2	-	26627737	HCT116	viability after 6 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	-0.7787035250352703	[850]	[193,13]	-4	hSpCas9	negative selection	1799774
43551835	43551858	2	+	26627737	HCT116	viability after 6 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.10484652443668747	[595]	[219,34]	0	hSpCas9	negative selection	1799775
43556358	43556381	2	-	26627737	HCT116	viability after 6 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.5643398528265778	[1201]	[417,202]	3	hSpCas9	negative selection	1799776
43574836	43574859	2	+	26627737	HCT116	viability after 6 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	0.8943506467596897	[509]	[382,19]	5	hSpCas9	negative selection	1799777
43592327	43592350	2	+	26627737	HCT116	viability after 6 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.8734455682201355	[1068]	[216,357]	5	hSpCas9	negative selection	1799778
43498907	43498930	2	-	26627737	HCT116	viability after 8 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.8082338188515992	[67]	[106,59,30]	7	hSpCas9	negative selection	1882088
43541278	43541301	2	-	26627737	HCT116	viability after 8 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	0.15304837705530602	[244]	[192,99,157]	1	hSpCas9	negative selection	1882089
43551835	43551858	2	+	26627737	HCT116	viability after 8 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.08586934023390423	[305]	[154,248,132]	1	hSpCas9	negative selection	1882090
43556358	43556381	2	-	26627737	HCT116	viability after 8 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.052692966055120305	[768]	[393,426,495]	0	hSpCas9	negative selection	1882091
43574836	43574859	2	+	26627737	HCT116	viability after 8 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.03726946171824319	[183]	[142,38,114]	0	hSpCas9	negative selection	1882092
43592327	43592350	2	+	26627737	HCT116	viability after 8 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.39910535993588936	[608]	[368,576,380]	4	hSpCas9	negative selection	1882093
43498907	43498930	2	-	26627737	HCT116	viability after 9 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-0.11424610143971514	[284]	[157,0]	-1	hSpCas9	negative selection	1964403
43541278	43541301	2	-	26627737	HCT116	viability after 9 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	-0.031912802946196306	[850]	[214,227]	0	hSpCas9	negative selection	1964404
43551835	43551858	2	+	26627737	HCT116	viability after 9 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-1.2259515260969576	[595]	[19,105]	-7	hSpCas9	negative selection	1964405
43556358	43556381	2	-	26627737	HCT116	viability after 9 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	1.1563313353427098	[1201]	[644,770]	7	hSpCas9	negative selection	1964406
43574836	43574859	2	+	26627737	HCT116	viability after 9 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-2.6322970812352833	[509]	[7,32]	-9	hSpCas9	negative selection	1964407
43592327	43592350	2	+	26627737	HCT116	viability after 9 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.8483406265219816	[1068]	[590,452]	6	hSpCas9	negative selection	1964408
43498907	43498930	2	-	26627737	HCT116	viability after 12 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	1.0836637159704372	[67]	[77,74,73]	8	hSpCas9	negative selection	2046718
43541278	43541301	2	-	26627737	HCT116	viability after 12 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	0.31818845363409726	[244]	[191,126,158]	3	hSpCas9	negative selection	2046719
43551835	43551858	2	+	26627737	HCT116	viability after 12 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.14052620244059275	[305]	[172,252,107]	1	hSpCas9	negative selection	2046720
43556358	43556381	2	-	26627737	HCT116	viability after 12 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.19795554001247817	[768]	[389,291,710]	2	hSpCas9	negative selection	2046721
43574836	43574859	2	+	26627737	HCT116	viability after 12 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.408389460080511	[183]	[70,124,23]	-4	hSpCas9	negative selection	2046722
43592327	43592350	2	+	26627737	HCT116	viability after 12 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.10258934464058522	[608]	[309,390,333]	1	hSpCas9	negative selection	2046723
43498907	43498930	2	-	26627737	HCT116	viability after 15 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.30925256699466264	[67]	[93,31,24]	3	hSpCas9	negative selection	2129033
43541278	43541301	2	-	26627737	HCT116	viability after 15 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	-0.11015525443192847	[244]	[180,65,149]	-1	hSpCas9	negative selection	2129034
43551835	43551858	2	+	26627737	HCT116	viability after 15 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.12986443941365278	[305]	[331,163,98]	1	hSpCas9	negative selection	2129035
43556358	43556381	2	-	26627737	HCT116	viability after 15 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	-0.046197180479147004	[768]	[542,311,441]	0	hSpCas9	negative selection	2129036
43574836	43574859	2	+	26627737	HCT116	viability after 15 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.6194084946676653	[183]	[67,47,89]	-6	hSpCas9	negative selection	2129037
43592327	43592350	2	+	26627737	HCT116	viability after 15 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.07226319922642288	[608]	[569,376,182]	0	hSpCas9	negative selection	2129038
43498907	43498930	2	-	26627737	HCT116	viability after 18 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.839260161683286	[67]	[70,31,75]	6	hSpCas9	negative selection	2211348
43541278	43541301	2	-	26627737	HCT116	viability after 18 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	0.7220476601815297	[244]	[295,120,172]	6	hSpCas9	negative selection	2211349
43551835	43551858	2	+	26627737	HCT116	viability after 18 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.11522073688359705	[305]	[216,142,119]	1	hSpCas9	negative selection	2211350
43556358	43556381	2	-	26627737	HCT116	viability after 18 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.6522262935560279	[768]	[736,288,753]	5	hSpCas9	negative selection	2211351
43574836	43574859	2	+	26627737	HCT116	viability after 18 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.9550039365900121	[183]	[80,19,37]	-7	hSpCas9	negative selection	2211352
43592327	43592350	2	+	26627737	HCT116	viability after 18 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.04045542184797246	[608]	[287,354,259]	0	hSpCas9	negative selection	2211353
43352685	43352708	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAAAGAGAAAGAGAGAGAGAG	THADA	ENSG00000115970	0.039126650339510544	[163,24]	[27,12]	0	dCas9-VP64	positive selection	2385811
43432131	43432154	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCGCGCCCGG	THADA	ENSG00000115970	-0.8581528486253212	[26,35]	[2,3]	-5	dCas9-VP64	positive selection	2392134
43261459	43261482	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGTCTTGCTCTGTCGCCCAGG	THADA	ENSG00000115970	1.2077108984929388	[2,0]	[0,0]	5	dCas9-VP64	positive selection	2399336
43295947	43295970	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCGCTCTGTCGCCCAGGCAGG	THADA	ENSG00000115970	-0.2966468943215429	[82,22]	[4,12]	-1	dCas9-VP64	positive selection	2413496
43548380	43548403	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GACAGCTTTGAAGAGAGCAGCGG	THADA	ENSG00000115970	-0.6121471750215912	[154,378]	[38,37]	-3	dCas9-VP64	positive selection	2420212
43310892	43310915	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAGCCACCGCGCCCAGCCGAG	THADA	ENSG00000115970	-0.6476236116882323	[118,215]	[30,13]	-3	dCas9-VP64	positive selection	2438043
43316665	43316688	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CATCTGTAATCCCAGCACTTAGG	THADA	ENSG00000115970	0.936948372456865	[294,1308]	[29,678]	4	dCas9-VP64	positive selection	2456804
43352685	43352708	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAAAGAGAAAGAGAGAGAGAG	THADA	ENSG00000115970	1.133413249914112	[120,136]	[88,94]	7	dCas9-VP64	positive selection	2481066
43432131	43432154	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCGCGCCCGG	THADA	ENSG00000115970	-0.2201981089703296	[184,135]	[60,29]	-2	dCas9-VP64	positive selection	2487389
43261459	43261482	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGTCTTGCTCTGTCGCCCAGG	THADA	ENSG00000115970	-0.1122041493399547	[42,120]	[2,43]	-1	dCas9-VP64	positive selection	2494591
43295947	43295970	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCGCTCTGTCGCCCAGGCAGG	THADA	ENSG00000115970	1.7427299536741634	[67,144]	[186,48]	8	dCas9-VP64	positive selection	2508751
43548380	43548403	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GACAGCTTTGAAGAGAGCAGCGG	THADA	ENSG00000115970	-0.16755709643747352	[346,251]	[113,61]	-2	dCas9-VP64	positive selection	2515467
43310892	43310915	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAGCCACCGCGCCCAGCCGAG	THADA	ENSG00000115970	-0.5349507089340686	[327,308]	[84,58]	-5	dCas9-VP64	positive selection	2533298
43316665	43316688	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CATCTGTAATCCCAGCACTTAGG	THADA	ENSG00000115970	-0.19682723409902197	[171,197]	[36,65]	-2	dCas9-VP64	positive selection	2552059
43586936	43586959	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGAAGACGAGAAGTAAAACGG	THADA	ENSG00000115970	0.4184644128569584	[3,2]	[2,3]	8	hSpCas9	positive selection	3026570
43577150	43577173	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	-0.16821103134736368	[3,3]	[2,2]	-2	hSpCas9	positive selection	3026571
43577178	43577201	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCTGCTCATAAACCACTCGG	THADA	ENSG00000115970	0.27102872591874616	[4,4]	[4,5]	6	hSpCas9	positive selection	3026572
43590927	43590950	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATCTGCTTTCTCCAGCAGAGG	THADA	ENSG00000115970	-0.3051144297395187	[3,4]	[3,1]	-4	hSpCas9	positive selection	3026573
43586936	43586959	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGAAGACGAGAAGTAAAACGG	THADA	ENSG00000115970	-0.5216362188654664	[3,3]	[2,0]	-7	hSpCas9	positive selection	3094428
43577150	43577173	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	-0.10312402788306795	[3,3]	[1,2]	-1	hSpCas9	positive selection	3094429
43577178	43577201	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCTGCTCATAAACCACTCGG	THADA	ENSG00000115970	0.3446136171820581	[4,4]	[5,3]	6	hSpCas9	positive selection	3094430
43590927	43590950	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATCTGCTTTCTCCAGCAGAGG	THADA	ENSG00000115970	-0.1314530438020447	[3,3]	[3,1]	-2	hSpCas9	positive selection	3094431
43590939	43590962		-	24336571	A375	resistance to PLX after 7 days	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.4263254811472868	[6,6]	[9,8]	9	hSpCas9	positive selection	3150080
43591945	43591968		+	24336571	A375	resistance to PLX after 7 days	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.012619428952646894	[3,3]	[3,3]	0	hSpCas9	positive selection	3150081
43591984	43592007		-	24336571	A375	resistance to PLX after 7 days	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.04205180415621684	[18,17]	[16,17]	-1	hSpCas9	positive selection	3150082
43592032	43592055		-	24336571	A375	resistance to PLX after 7 days	TTATATAGCTTTTGCTGATGTGG	THADA	ENSG00000115970	0.3308292884596853	[12,10]	[16,13]	8	hSpCas9	positive selection	3150083
43590939	43590962		-	24336571	A375	resistance to PLX after 14 days	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.4181396753565878	[9,7]	[5,4]	4	hSpCas9	positive selection	3207873
43591945	43591968		+	24336571	A375	resistance to PLX after 14 days	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.19148238327506295	[1,4]	[1,1]	2	hSpCas9	positive selection	3207874
43591984	43592007		-	24336571	A375	resistance to PLX after 14 days	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-1.104697730176705	[17,17]	[3,2]	-9	hSpCas9	positive selection	3207875
43592032	43592055		-	24336571	A375	resistance to PLX after 14 days	TTATATAGCTTTTGCTGATGTGG	THADA	ENSG00000115970	0.027777162487510113	[14,10]	[6,4]	0	hSpCas9	positive selection	3207876
43590939	43590962		-	24336571	A375	viability after 7 days	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.12445675450572957	[6]	[6,6]	2	hSpCas9	negative selection	3265666
43591945	43591968		+	24336571	A375	viability after 7 days	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	-0.9528494522216664	[8]	[3,3]	-8	hSpCas9	negative selection	3265667
43591984	43592007		-	24336571	A375	viability after 7 days	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.09378597253278792	[20]	[18,17]	-1	hSpCas9	negative selection	3265668
43592032	43592055		-	24336571	A375	viability after 7 days	TTATATAGCTTTTGCTGATGTGG	THADA	ENSG00000115970	0.23646631084339728	[10]	[12,10]	3	hSpCas9	negative selection	3265669
43590939	43590962		-	24336571	A375	viability after 14 days	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.49925868264707346	[6]	[9,7]	6	hSpCas9	negative selection	3323459
43591945	43591968		+	24336571	A375	viability after 14 days	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	-1.167954368805577	[8]	[1,4]	-9	hSpCas9	negative selection	3323460
43591984	43592007		-	24336571	A375	viability after 14 days	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.06524032202542507	[20]	[17,17]	0	hSpCas9	negative selection	3323461
43592032	43592055		-	24336571	A375	viability after 14 days	TTATATAGCTTTTGCTGATGTGG	THADA	ENSG00000115970	0.3586909639418341	[10]	[14,10]	4	hSpCas9	negative selection	3323462
43591984	43592007	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.49756129071763344	[215,215]	[0,0]	-3	hSpCas9	positive selection	3397016
43590888	43590911	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	-0.8301366298045043	[271,271]	[0,0]	-5	hSpCas9	positive selection	3397017
43591945	43591968	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	-0.03729453744579207	[156,156]	[0,0]	0	hSpCas9	positive selection	3397018
43586935	43586958	2	+	26780180	HT29	viability (Avana library 4 designs)	CCTGAAGACGAGAAGTAAAACGG	THADA	ENSG00000115970	0.574117688903524	[]	[]	2	hSpCas9	negative selection	3465309
43577149	43577172	2	+	26780180	HT29	viability (Avana library 4 designs)	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	0.785831715926276	[]	[]	3	hSpCas9	negative selection	3465310
43577177	43577200	2	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCTGCTCATAAACCACTCGG	THADA	ENSG00000115970	-0.747477534626591	[]	[]	-8	hSpCas9	negative selection	3465311
43590926	43590949	2	+	26780180	HT29	viability (Avana library 4 designs)	TTATCTGCTTTCTCCAGCAGAGG	THADA	ENSG00000115970	1.76687408844144	[]	[]	6	hSpCas9	negative selection	3465312
43586935	43586958	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGAAGACGAGAAGTAAAACGG	THADA	ENSG00000115970	-2.1550865104822	[]	[]	-3	hSpCas9	negative selection	3568440
43577149	43577172	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	2.62765544732057	[]	[]	4	hSpCas9	negative selection	3568441
43577177	43577200	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTGCTCATAAACCACTCGG	THADA	ENSG00000115970	3.78857385431397	[]	[]	6	hSpCas9	negative selection	3568442
43590926	43590949	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATCTGCTTTCTCCAGCAGAGG	THADA	ENSG00000115970	0.0253282570508236	[]	[]	0	hSpCas9	negative selection	3568443
43574927	43574950	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.95285867517664	[]	[]	1	hSpCas9	negative selection	3568444
43577192	43577215	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGCACCAGTGTCCCCGAGTGG	THADA	ENSG00000115970	3.74739711400872	[]	[]	6	hSpCas9	negative selection	3568445
43586935	43586958	2	+	26780180	A375	viability (Avana lentiGuide)	CCTGAAGACGAGAAGTAAAACGG	THADA	ENSG00000115970	-7.71122451165703	[]	[]	-9	hSpCas9	negative selection	3677099
43577149	43577172	2	+	26780180	A375	viability (Avana lentiGuide)	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	2.54589903699341	[]	[]	2	hSpCas9	negative selection	3677100
43577177	43577200	2	+	26780180	A375	viability (Avana lentiGuide)	GCAGCTGCTCATAAACCACTCGG	THADA	ENSG00000115970	-3.85645698946006	[]	[]	-6	hSpCas9	negative selection	3677101
43590926	43590949	2	+	26780180	A375	viability (Avana lentiGuide)	TTATCTGCTTTCTCCAGCAGAGG	THADA	ENSG00000115970	-0.522191170782124	[]	[]	-1	hSpCas9	negative selection	3677102
43574927	43574950	2	-	26780180	A375	viability (Avana lentiGuide)	ATCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	-0.655613856978139	[]	[]	-1	hSpCas9	negative selection	3677103
43577192	43577215	2	-	26780180	A375	viability (Avana lentiGuide)	ACTGCACCAGTGTCCCCGAGTGG	THADA	ENSG00000115970	-1.81437235892083	[]	[]	-3	hSpCas9	negative selection	3677104
43586935	43586958	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGAAGACGAGAAGTAAAACGG	THADA	ENSG00000115970	-0.5292150578742015	[4]	[3,1]	-6	hSpCas9	positive selection	3785706
43577149	43577172	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	-0.05363181598719341	[4]	[4,3]	-1	hSpCas9	positive selection	3785707
43577177	43577200	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTGCTCATAAACCACTCGG	THADA	ENSG00000115970	0.06046321361813824	[5]	[5,5]	1	hSpCas9	positive selection	3785708
43590926	43590949	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATCTGCTTTCTCCAGCAGAGG	THADA	ENSG00000115970	0.004371431162362632	[6]	[5,6]	0	hSpCas9	positive selection	3785709
43574927	43574950	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	-0.039520738603123884	[6]	[6,5]	0	hSpCas9	positive selection	3785710
43577192	43577215	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGCACCAGTGTCCCCGAGTGG	THADA	ENSG00000115970	0.27360657898205837	[5]	[6,6]	7	hSpCas9	positive selection	3785711
43586935	43586958	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGAAGACGAGAAGTAAAACGG	THADA	ENSG00000115970	0.24948613077584464	[4]	[5,2]	6	hSpCas9	positive selection	3894313
43577149	43577172	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	-0.39946128576925877	[4]	[1,3]	-5	hSpCas9	positive selection	3894314
43577177	43577200	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTGCTCATAAACCACTCGG	THADA	ENSG00000115970	0.24168545485597132	[6]	[6,6]	6	hSpCas9	positive selection	3894315
43590926	43590949	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATCTGCTTTCTCCAGCAGAGG	THADA	ENSG00000115970	0.18998014639075944	[5]	[5,5]	4	hSpCas9	positive selection	3894316
43574927	43574950	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.09803358032409656	[5]	[4,5]	2	hSpCas9	positive selection	3894317
43577192	43577215	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGCACCAGTGTCCCCGAGTGG	THADA	ENSG00000115970	0.17078742195107663	[6]	[6,5]	4	hSpCas9	positive selection	3894318
43590939	43590962	2	-	26780180	A375	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	1.60452278009255	[]	[]	8	hSpCas9	negative selection	4003661
43586855	43586878	2	+	26780180	A375	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	1.25016260040203	[]	[]	6	hSpCas9	negative selection	4003662
43586900	43586923	2	-	26780180	A375	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.976923787991365	[]	[]	4	hSpCas9	negative selection	4003663
43591945	43591968	2	+	26780180	A375	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.895147718431647	[]	[]	4	hSpCas9	negative selection	4003664
43591984	43592007	2	-	26780180	A375	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	1.15605075833913	[]	[]	6	hSpCas9	negative selection	4003665
43590888	43590911	2	-	26780180	A375	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.386441478133634	[]	[]	0	hSpCas9	negative selection	4003666
43590939	43590962	2	-	26780180	HT29	viability (GeCKOv2 library)	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	1.55889918797419	[]	[]	8	hSpCas9	negative selection	4111627
43586855	43586878	2	+	26780180	HT29	viability (GeCKOv2 library)	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	2.27985282407356	[]	[]	9	hSpCas9	negative selection	4111628
43586900	43586923	2	-	26780180	HT29	viability (GeCKOv2 library)	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	1.39108586922119	[]	[]	7	hSpCas9	negative selection	4111629
43591945	43591968	2	+	26780180	HT29	viability (GeCKOv2 library)	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	-0.116178994730035	[]	[]	-3	hSpCas9	negative selection	4111630
43591984	43592007	2	-	26780180	HT29	viability (GeCKOv2 library)	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	0.828502836895919	[]	[]	3	hSpCas9	negative selection	4111631
43590888	43590911	2	-	26780180	HT29	viability (GeCKOv2 library)	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	-0.283910785608122	[]	[]	-7	hSpCas9	negative selection	4111632
43590939	43590962	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.2196082310125717	[2]	[1,2]	5	hSpCas9	positive selection	4176455
43591945	43591968	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.35975194905147434	[0]	[1,0]	8	hSpCas9	positive selection	4176456
43591984	43592007	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.3299190817009717	[4]	[2,1]	-7	hSpCas9	positive selection	4176457
43592032	43592055	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTATATAGCTTTTGCTGATGTGG	THADA	ENSG00000115970	0.022247990594150998	[3]	[2,2]	0	hSpCas9	positive selection	4176458
43590939	43590962	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	-0.17356083929995736	[2]	[0,0,1,0]	-2	hSpCas9	positive selection	4240477
43591945	43591968	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.861264212250716	[1]	[3,0,1,0]	5	hSpCas9	positive selection	4240478
43591984	43592007	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	0.7752583108120319	[4]	[3,2,1,3]	5	hSpCas9	positive selection	4240479
43592032	43592055	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTATATAGCTTTTGCTGATGTGG	THADA	ENSG00000115970	0.6107748515265587	[3]	[1,0,1,3]	4	hSpCas9	positive selection	4240480
43590939	43590962	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	-0.05590442145155599	[3]	[2,1]	-1	hSpCas9	positive selection	4302904
43586855	43586878	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.04167118387980459	[2]	[1,1]	-1	hSpCas9	positive selection	4302905
43586900	43586923	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.06510599112388159	[3]	[3,1]	-1	hSpCas9	positive selection	4302906
43591984	43592007	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.3584391219752421	[3]	[3,0]	-6	hSpCas9	positive selection	4367158
43590888	43590911	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.3661788311229862	[3]	[3,2]	7	hSpCas9	positive selection	4367159
43591945	43591968	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.06430194654196986	[2]	[2,1]	1	hSpCas9	positive selection	4367160
43574723	43574745	2	-	27760321	OCIAML3	viability	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	-0.5526777729664505	[110,83]	[51,50]	-5	hSpCas9	negative selection	4446676
43574786	43574808	2	-	27760321	OCIAML3	viability	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	0.21469413020731043	[1077,893]	[725,1105]	2	hSpCas9	negative selection	4446677
43574851	43574873	2	+	27760321	OCIAML3	viability	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	0.685458945312789	[236,181]	[264,256]	7	hSpCas9	negative selection	4446678
43574927	43574949	2	-	27760321	OCIAML3	viability	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.06729592018480537	[453,392]	[392,284]	0	hSpCas9	negative selection	4446679
43577187	43577209	2	+	27760321	OCIAML3	viability	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	-0.15086496317142442	[525,383]	[280,364]	-2	hSpCas9	negative selection	4446680
43574723	43574745	2	-	27760321	OCIAML2	viability	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	-0.4601380113824751	[110,83]	[33,86]	-5	hSpCas9	negative selection	4530139
43574786	43574808	2	-	27760321	OCIAML2	viability	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	-0.04138791162902544	[1077,893]	[712,848]	0	hSpCas9	negative selection	4530140
43574851	43574873	2	+	27760321	OCIAML2	viability	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	0.25542825798071433	[236,181]	[189,214]	3	hSpCas9	negative selection	4530141
43574927	43574949	2	-	27760321	OCIAML2	viability	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.6876017233478792	[453,392]	[438,696]	8	hSpCas9	negative selection	4530142
43577187	43577209	2	+	27760321	OCIAML2	viability	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	-0.1711714322090141	[525,383]	[271,391]	-2	hSpCas9	negative selection	4530143
43574723	43574745	2	-	27760321	MV411	viability	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	-1.749150947807498	[110,83]	[0,45]	-8	hSpCas9	negative selection	4613602
43574786	43574808	2	-	27760321	MV411	viability	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	0.4710603690330992	[1077,893]	[1084,616]	3	hSpCas9	negative selection	4613603
43574851	43574873	2	+	27760321	MV411	viability	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	1.8170205361878775	[236,181]	[574,345]	9	hSpCas9	negative selection	4613604
43574927	43574949	2	-	27760321	MV411	viability	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	1.8820988448827596	[453,392]	[837,1311]	9	hSpCas9	negative selection	4613605
43577187	43577209	2	+	27760321	MV411	viability	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	1.2552568170789864	[525,383]	[842,509]	8	hSpCas9	negative selection	4613606
43574723	43574745	2	-	27760321	HL60	viability	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	0.5170049772171679	[110,83]	[180,40]	6	hSpCas9	negative selection	4697065
43574786	43574808	2	-	27760321	HL60	viability	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	-0.03351617332191226	[1077,893]	[766,800]	0	hSpCas9	negative selection	4697066
43574851	43574873	2	+	27760321	HL60	viability	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	-0.5941809746552067	[236,181]	[112,111]	-6	hSpCas9	negative selection	4697067
43574927	43574949	2	-	27760321	HL60	viability	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.09101141765258189	[453,392]	[433,296]	1	hSpCas9	negative selection	4697068
43577187	43577209	2	+	27760321	HL60	viability	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	-0.5552108809690316	[525,383]	[284,213]	-6	hSpCas9	negative selection	4697069
43574723	43574745	2	-	27760321	HT1080	viability	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	1.314224181546638	[83,65]	[17,135]	7	hSpCas9	negative selection	4780528
43574786	43574808	2	-	27760321	HT1080	viability	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	0.8127370893322159	[893,697]	[588,521]	4	hSpCas9	negative selection	4780529
43574851	43574873	2	+	27760321	HT1080	viability	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	-0.41556852581509784	[181,141]	[66,27]	-2	hSpCas9	negative selection	4780530
43574927	43574949	2	-	27760321	HT1080	viability	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	1.3699551868811617	[392,306]	[315,408]	7	hSpCas9	negative selection	4780531
43577187	43577209	2	+	27760321	HT1080	viability	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	2.050878005376901	[383,299]	[565,562]	9	hSpCas9	negative selection	4780532
43574723	43574745	2	-	27760321	HT29	viability after 7 days	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	-1.5390191144847196	[83,65]	[36,58,4]	-9	hSpCas9	negative selection	4863991
43574786	43574808	2	-	27760321	HT29	viability after 7 days	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	0.4015876999358392	[893,697]	[1366,891,1782]	6	hSpCas9	negative selection	4863992
43574851	43574873	2	+	27760321	HT29	viability after 7 days	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	0.692952582440387	[181,141]	[205,384,397]	9	hSpCas9	negative selection	4863993
43574927	43574949	2	-	27760321	HT29	viability after 7 days	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.4701292498938826	[392,306]	[711,517,650]	7	hSpCas9	negative selection	4863994
43577187	43577209	2	+	27760321	HT29	viability after 7 days	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	0.33641898264425374	[383,299]	[538,645,479]	5	hSpCas9	negative selection	4863995
43574723	43574745	2	-	27760321	HT29	viability after 25 days	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	0.18945306848224996	[83,65]	[117,152,11]	2	hSpCas9	negative selection	4947454
43574786	43574808	2	-	27760321	HT29	viability after 25 days	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	0.1312682706362116	[893,697]	[877,896,1245]	1	hSpCas9	negative selection	4947455
43574851	43574873	2	+	27760321	HT29	viability after 25 days	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	0.2048493954631354	[181,141]	[284,173,171]	2	hSpCas9	negative selection	4947456
43574927	43574949	2	-	27760321	HT29	viability after 25 days	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.5539497522262288	[392,306]	[667,627,444]	6	hSpCas9	negative selection	4947457
43577187	43577209	2	+	27760321	HT29	viability after 25 days	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	-0.025694209910303925	[383,299]	[262,433,470]	0	hSpCas9	negative selection	4947458
43574723	43574745	2	-	27760321	HT29	viability after 22 days	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	0.029244245614329145	[83,65]	[172,28,60]	0	hSpCas9	negative selection	5030917
43574786	43574808	2	-	27760321	HT29	viability after 22 days	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	0.3445958497324326	[893,697]	[1179,1279,1043]	3	hSpCas9	negative selection	5030918
43574851	43574873	2	+	27760321	HT29	viability after 22 days	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	0.14636461057465278	[181,141]	[128,279,214]	1	hSpCas9	negative selection	5030919
43574927	43574949	2	-	27760321	HT29	viability after 22 days	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.7672887317697289	[392,306]	[843,523,693]	8	hSpCas9	negative selection	5030920
43577187	43577209	2	+	27760321	HT29	viability after 22 days	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	0.33328064842380684	[383,299]	[692,313,481]	3	hSpCas9	negative selection	5030921
43574723	43574745	2	-	27760321	HT29	viability after 19 days	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	1.6468186896424704	[83,65]	[45,557,181]	9	hSpCas9	negative selection	5114380
43574786	43574808	2	-	27760321	HT29	viability after 19 days	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	0.21138036383863978	[893,697]	[1179,1004,991]	2	hSpCas9	negative selection	5114381
43574851	43574873	2	+	27760321	HT29	viability after 19 days	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	0.1845180851521444	[181,141]	[309,203,130]	1	hSpCas9	negative selection	5114382
43574927	43574949	2	-	27760321	HT29	viability after 19 days	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.7118987054418436	[392,306]	[524,880,550]	7	hSpCas9	negative selection	5114383
43577187	43577209	2	+	27760321	HT29	viability after 19 days	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	0.11053683785189003	[383,299]	[671,391,235]	1	hSpCas9	negative selection	5114384
43574723	43574745	2	-	27760321	HT29	viability after 16 days	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	0.045044552629639245	[83,65]	[108,121,29]	0	hSpCas9	negative selection	5197843
43574786	43574808	2	-	27760321	HT29	viability after 16 days	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	0.38708039815357176	[893,697]	[1189,1401,897]	4	hSpCas9	negative selection	5197844
43574851	43574873	2	+	27760321	HT29	viability after 16 days	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	0.33192666407701077	[181,141]	[194,159,327]	3	hSpCas9	negative selection	5197845
43574927	43574949	2	-	27760321	HT29	viability after 16 days	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.2364916208361564	[392,306]	[497,478,409]	2	hSpCas9	negative selection	5197846
43577187	43577209	2	+	27760321	HT29	viability after 16 days	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	0.25295810528577756	[383,299]	[395,617,343]	2	hSpCas9	negative selection	5197847
43574723	43574745	2	-	27760321	HT29	viability after 13 days	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	0.021818325661509874	[83,65]	[60,78,122]	0	hSpCas9	negative selection	5281306
43574786	43574808	2	-	27760321	HT29	viability after 13 days	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	0.22612801470592636	[893,697]	[995,1257,991]	3	hSpCas9	negative selection	5281307
43574851	43574873	2	+	27760321	HT29	viability after 13 days	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	0.7487175251724604	[181,141]	[175,342,421]	8	hSpCas9	negative selection	5281308
43574927	43574949	2	-	27760321	HT29	viability after 13 days	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.33679752976340677	[392,306]	[603,349,579]	4	hSpCas9	negative selection	5281309
43577187	43577209	2	+	27760321	HT29	viability after 13 days	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	-0.10514704803117413	[383,299]	[400,480,232]	-1	hSpCas9	negative selection	5281310
43574723	43574745	2	-	27760321	HT29	viability after 10 days	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	0.10391780074041357	[83,65]	[49,102,147]	1	hSpCas9	negative selection	5364769
43574786	43574808	2	-	27760321	HT29	viability after 10 days	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	0.1544154211322859	[893,697]	[1293,1176,854]	2	hSpCas9	negative selection	5364770
43574851	43574873	2	+	27760321	HT29	viability after 10 days	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	0.0807473761001245	[181,141]	[182,173,281]	1	hSpCas9	negative selection	5364771
43574927	43574949	2	-	27760321	HT29	viability after 10 days	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	0.9842033877865833	[392,306]	[1089,1075,442]	9	hSpCas9	negative selection	5364772
43577187	43577209	2	+	27760321	HT29	viability after 10 days	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	0.06978739298083278	[383,299]	[458,432,451]	0	hSpCas9	negative selection	5364773
43574723	43574745	2	-	27760321	MOLM13	viability	ACTGAGAGTCTTTTACGATTGG	THADA	ENSG00000115970	0.7867027918460388	[110,83]	[125,66]	5	hSpCas9	negative selection	5448232
43574786	43574808	2	-	27760321	MOLM13	viability	CAAATGCACCGGCTCACTGTGG	THADA	ENSG00000115970	0.22733006410713097	[1077,893]	[353,898]	1	hSpCas9	negative selection	5448233
43574851	43574873	2	+	27760321	MOLM13	viability	TCCAATGGATGTTCCCAATGGG	THADA	ENSG00000115970	0.01231835541659132	[236,181]	[187,58]	0	hSpCas9	negative selection	5448234
43574927	43574949	2	-	27760321	MOLM13	viability	TCAAGTTCCCCGAGCCTAACGG	THADA	ENSG00000115970	2.0055794476127766	[453,392]	[1468,520]	9	hSpCas9	negative selection	5448235
43577187	43577209	2	+	27760321	MOLM13	viability	ATAAACCACTCGGGGACACTGG	THADA	ENSG00000115970	1.6998008291188702	[525,383]	[1195,510]	9	hSpCas9	negative selection	5448236
43595728	43595751	2	+	27661255	K562	viability	GTGGAGTCGAGGAATGACAGTGG	THADA	ENSG00000115970	0.1867672829012852	[1574,1878]	[1744,1411]	6	dCas9-KRAB	negative selection	5517071
43595960	43595983	2	+	27661255	K562	viability	GCAGGCGCCTGGTCCAGTCCCGG	THADA	ENSG00000115970	0.13043096693876385	[667,669]	[612,560]	4	dCas9-KRAB	negative selection	5517072
43595978	43596001	2	-	27661255	K562	viability	GTAGAAGGAGACCTGCTTCCGGG	THADA	ENSG00000115970	0.07823511931837257	[2660,2609]	[2448,2030]	2	dCas9-KRAB	negative selection	5517073
43596008	43596031	2	-	27661255	K562	viability	GTGGACCGCGCTGCGAGCCTCGG	THADA	ENSG00000115970	-0.0009007255789200697	[1139,1142]	[975,855]	0	dCas9-KRAB	negative selection	5517074
43590939	43590962	2	-	27260156	BXPC3	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.013873565685221578	[593]	[661,589,631,616]	0	hSpCas9	negative selection	5575364
43586855	43586878	2	+	27260156	BXPC3	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.03498705201751329	[281]	[284,203,387,277]	-1	hSpCas9	negative selection	5575365
43586900	43586923	2	-	27260156	BXPC3	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.12056287203258709	[658]	[513,672,705,651]	-3	hSpCas9	negative selection	5575366
43591984	43592007	2	-	27260156	BXPC3	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.07646245317174974	[522]	[475,426,475,726]	-2	hSpCas9	negative selection	5639618
43590888	43590911	2	-	27260156	BXPC3	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.5955016738629083	[483]	[753,581,851,894]	9	hSpCas9	negative selection	5639619
43591945	43591968	2	+	27260156	BXPC3	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.27158099762230115	[226]	[258,309,278,298]	6	hSpCas9	negative selection	5639620
43590939	43590962	2	-	27260156	A673	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	-0.08934139331042734	[593]	[729,568,695,695]	-2	hSpCas9	negative selection	5696615
43586855	43586878	2	+	27260156	A673	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.3242809198228692	[281]	[370,273,244,198]	-7	hSpCas9	negative selection	5696616
43586900	43586923	2	-	27260156	A673	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.10133864092885897	[658]	[827,704,582,851]	-3	hSpCas9	negative selection	5696617
43591984	43592007	2	-	27260156	A673	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.13677332432727884	[522]	[690,546,573,480]	-3	hSpCas9	negative selection	5760869
43590888	43590911	2	-	27260156	A673	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.4909641772083909	[483]	[828,829,770,837]	9	hSpCas9	negative selection	5760870
43591945	43591968	2	+	27260156	A673	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.025208006679154904	[226]	[235,273,270,325]	0	hSpCas9	negative selection	5760871
43590939	43590962	2	-	27260156	A375	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.07789194051829379	[593]	[965,684,543,726]	1	hSpCas9	negative selection	5817866
43586855	43586878	2	+	27260156	A375	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.31224747182973445	[281]	[293,314,218,241]	-4	hSpCas9	negative selection	5817867
43586900	43586923	2	-	27260156	A375	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.2710010187945151	[658]	[1250,871,719,869]	4	hSpCas9	negative selection	5817868
43591984	43592007	2	-	27260156	A375	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	0.10533725328465363	[522]	[487,834,849,495]	1	hSpCas9	negative selection	5882120
43590888	43590911	2	-	27260156	A375	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.9845765737300335	[483]	[1437,1387,788,918]	9	hSpCas9	negative selection	5882121
43591945	43591968	2	+	27260156	A375	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.8897078893398018	[226]	[468,333,738,408]	9	hSpCas9	negative selection	5882122
43590939	43590962	2	-	27260156	COLO741	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	-0.028157130632797123	[593]	[695,1006,539]	0	hSpCas9	negative selection	5939117
43586855	43586878	2	+	27260156	COLO741	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.06800565220126809	[281]	[310,432,287]	-1	hSpCas9	negative selection	5939118
43586900	43586923	2	-	27260156	COLO741	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.06921396727404339	[658]	[990,892,780]	1	hSpCas9	negative selection	5939119
43591984	43592007	2	-	27260156	COLO741	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	0.020331376806333207	[522]	[801,604,637]	0	hSpCas9	negative selection	6003371
43590888	43590911	2	-	27260156	COLO741	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.4752909787486348	[483]	[844,954,781]	8	hSpCas9	negative selection	6003372
43591945	43591968	2	+	27260156	COLO741	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.3242816512285124	[226]	[382,465,249]	6	hSpCas9	negative selection	6003373
43590939	43590962	2	-	27260156	CAL120	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.09401820074921952	[593]	[526,726,1067]	1	hSpCas9	negative selection	6060368
43586855	43586878	2	+	27260156	CAL120	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	0.22639149270888792	[281]	[602,335,322]	3	hSpCas9	negative selection	6060369
43586900	43586923	2	-	27260156	CAL120	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.20646142918440247	[658]	[814,648,683]	-3	hSpCas9	negative selection	6060370
43591984	43592007	2	-	27260156	CAL120	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.1330544715709452	[522]	[683,694,417]	-2	hSpCas9	negative selection	6124622
43590888	43590911	2	-	27260156	CAL120	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.3971531696220978	[483]	[929,468,996]	6	hSpCas9	negative selection	6124623
43591945	43591968	2	+	27260156	CAL120	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.3902598971955782	[226]	[401,214,495]	6	hSpCas9	negative selection	6124624
43590939	43590962	2	-	27260156	CADOES1	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.24672957431478332	[593]	[659,908,564,481]	4	hSpCas9	negative selection	6181619
43586855	43586878	2	+	27260156	CADOES1	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.03134169244024054	[281]	[290,264,302,163]	0	hSpCas9	negative selection	6181620
43586900	43586923	2	-	27260156	CADOES1	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.022886532252785807	[658]	[591,508,653,659]	0	hSpCas9	negative selection	6181621
43591984	43592007	2	-	27260156	CADOES1	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.12016539149237346	[522]	[380,596,458,349]	-2	hSpCas9	negative selection	6245873
43590888	43590911	2	-	27260156	CADOES1	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.8114727884056444	[483]	[662,800,991,700]	9	hSpCas9	negative selection	6245874
43591945	43591968	2	+	27260156	CADOES1	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.23251936743404344	[226]	[202,170,219,403]	4	hSpCas9	negative selection	6245875
43590939	43590962	2	-	27260156	EWS502	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.2730120393839858	[593]	[893,789,603,727]	5	hSpCas9	negative selection	6302870
43586855	43586878	2	+	27260156	EWS502	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	0.007073970912403027	[281]	[183,360,398,265]	0	hSpCas9	negative selection	6302871
43586900	43586923	2	-	27260156	EWS502	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.0909472218584566	[658]	[646,1007,687,618]	1	hSpCas9	negative selection	6302872
43591984	43592007	2	-	27260156	EWS502	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	0.20379822012542712	[522]	[586,704,634,624]	3	hSpCas9	negative selection	6367124
43590888	43590911	2	-	27260156	EWS502	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.7482007493735339	[483]	[682,933,875,974]	9	hSpCas9	negative selection	6367125
43591945	43591968	2	+	27260156	EWS502	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.519524073553209	[226]	[226,165,493,526]	8	hSpCas9	negative selection	6367126
43590939	43590962	2	-	27260156	EW8	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	-0.04301255021115291	[593]	[430,673,365,410]	-1	hSpCas9	negative selection	6424121
43586855	43586878	2	+	27260156	EW8	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.42822836372020234	[281]	[163,166,206,133]	-7	hSpCas9	negative selection	6424122
43586900	43586923	2	-	27260156	EW8	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.22351635369528933	[658]	[525,505,429,378]	-4	hSpCas9	negative selection	6424123
43591984	43592007	2	-	27260156	EW8	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.08437453757569656	[522]	[539,437,327,319]	-1	hSpCas9	negative selection	6488375
43590888	43590911	2	-	27260156	EW8	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.8392301070459633	[483]	[648,790,459,939]	9	hSpCas9	negative selection	6488376
43591945	43591968	2	+	27260156	EW8	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.28264172198954407	[226]	[261,257,127,266]	5	hSpCas9	negative selection	6488377
43590939	43590962	2	-	27260156	CORL105	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.27755330421410734	[593]	[735,858,936,849]	5	hSpCas9	negative selection	6545372
43586855	43586878	2	+	27260156	CORL105	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.04359598300117429	[281]	[424,211,333,317]	-1	hSpCas9	negative selection	6545373
43586900	43586923	2	-	27260156	CORL105	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.052413673373908454	[658]	[818,872,809,698]	1	hSpCas9	negative selection	6545374
43591984	43592007	2	-	27260156	CORL105	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.01788526885638106	[522]	[710,524,510,661]	0	hSpCas9	negative selection	6609626
43590888	43590911	2	-	27260156	CORL105	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.6660252083750006	[483]	[862,802,1036,914]	9	hSpCas9	negative selection	6609627
43591945	43591968	2	+	27260156	CORL105	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.3188147790474435	[226]	[340,361,339,283]	6	hSpCas9	negative selection	6609628
43590939	43590962	2	-	27260156	HS294T	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.22643281119530329	[593]	[228,306,298,235]	3	hSpCas9	negative selection	6666623
43586855	43586878	2	+	27260156	HS294T	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.4527402220511286	[281]	[49,55,86,138]	-6	hSpCas9	negative selection	6666624
43586900	43586923	2	-	27260156	HS294T	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.014599666536693812	[658]	[290,240,208,265]	0	hSpCas9	negative selection	6666625
43591984	43592007	2	-	27260156	HS294T	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.3752256402617894	[522]	[125,185,161,149]	-5	hSpCas9	negative selection	6730877
43590888	43590911	2	-	27260156	HS294T	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.7366416063905246	[483]	[192,351,181,572]	8	hSpCas9	negative selection	6730878
43591945	43591968	2	+	27260156	HS294T	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.7296541262283687	[226]	[115,110,116,260]	8	hSpCas9	negative selection	6730879
43590939	43590962	2	-	27260156	HCC44	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.04468027525668067	[593]	[621,790,826,533]	0	hSpCas9	negative selection	6787874
43586855	43586878	2	+	27260156	HCC44	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.353549995603358	[281]	[254,241,269,234]	-5	hSpCas9	negative selection	6787875
43586900	43586923	2	-	27260156	HCC44	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.2606090742951921	[658]	[1010,789,1155,684]	4	hSpCas9	negative selection	6787876
43591984	43592007	2	-	27260156	HCC44	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.20978024191737882	[522]	[507,688,292,488]	-3	hSpCas9	negative selection	6852128
43590888	43590911	2	-	27260156	HCC44	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.4603755934413889	[483]	[801,560,1104,634]	7	hSpCas9	negative selection	6852129
43591945	43591968	2	+	27260156	HCC44	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.2874759222733455	[226]	[362,200,444,285]	5	hSpCas9	negative selection	6852130
43590939	43590962	2	-	27260156	G402	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.09432338384275007	[593]	[652,604,1057,749]	1	hSpCas9	negative selection	6909125
43586855	43586878	2	+	27260156	G402	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.44654795978927886	[281]	[383,339,181,132]	-5	hSpCas9	negative selection	6909126
43586900	43586923	2	-	27260156	G402	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.42365772650500844	[658]	[1365,1040,1214,743]	5	hSpCas9	negative selection	6909127
43591984	43592007	2	-	27260156	G402	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.4084014381477714	[522]	[231,435,523,680]	-5	hSpCas9	negative selection	6973379
43590888	43590911	2	-	27260156	G402	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	1.0641143929481371	[483]	[1249,985,1424,1259]	9	hSpCas9	negative selection	6973380
43591945	43591968	2	+	27260156	G402	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	1.051993999551595	[226]	[360,662,748,499]	9	hSpCas9	negative selection	6973381
43590939	43590962	2	-	27260156	L33	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	-0.04466417295873598	[593]	[560,280,303,572]	-1	hSpCas9	negative selection	7030376
43586855	43586878	2	+	27260156	L33	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.580541518116379	[281]	[173,87,135,149]	-8	hSpCas9	negative selection	7030377
43586900	43586923	2	-	27260156	L33	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.03778039998694804	[658]	[589,279,529,592]	0	hSpCas9	negative selection	7030378
43591984	43592007	2	-	27260156	L33	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.4791209892542383	[522]	[430,129,208,417]	-8	hSpCas9	negative selection	7094630
43590888	43590911	2	-	27260156	L33	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.46075844027568114	[483]	[577,332,502,477]	8	hSpCas9	negative selection	7094631
43591945	43591968	2	+	27260156	L33	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.44638556505983806	[226]	[325,124,174,326]	8	hSpCas9	negative selection	7094632
43590939	43590962	2	-	27260156	K562	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.05088726987758907	[593]	[579,596,743,295]	0	hSpCas9	negative selection	7151627
43586855	43586878	2	+	27260156	K562	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.6081553889881463	[281]	[63,194,193,192]	-6	hSpCas9	negative selection	7151628
43586900	43586923	2	-	27260156	K562	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.1564715448594629	[658]	[508,1027,399,672]	2	hSpCas9	negative selection	7151629
43591984	43592007	2	-	27260156	K562	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.2964175483253957	[522]	[364,350,473,323]	-4	hSpCas9	negative selection	7215881
43590888	43590911	2	-	27260156	K562	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.7800039760056477	[483]	[1112,919,411,562]	8	hSpCas9	negative selection	7215882
43591945	43591968	2	+	27260156	K562	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.46409880742192156	[226]	[310,117,249,409]	6	hSpCas9	negative selection	7215883
43590939	43590962	2	-	27260156	HT29	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	-0.016109050941774006	[593]	[733,744,785,603]	0	hSpCas9	negative selection	7272878
43586855	43586878	2	+	27260156	HT29	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.01712546299070339	[281]	[322,370,427,243]	0	hSpCas9	negative selection	7272879
43586900	43586923	2	-	27260156	HT29	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.0604677853887341	[658]	[1028,887,693,753]	1	hSpCas9	negative selection	7272880
43591984	43592007	2	-	27260156	HT29	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.05264240607794553	[522]	[489,858,531,581]	-1	hSpCas9	negative selection	7337132
43590888	43590911	2	-	27260156	HT29	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.4975631539215559	[483]	[784,1005,606,918]	8	hSpCas9	negative selection	7337133
43591945	43591968	2	+	27260156	HT29	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.4860035825535487	[226]	[438,350,357,394]	8	hSpCas9	negative selection	7337134
43590939	43590962	2	-	27260156	MHHES1	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.08434764622212848	[593]	[843,630,555,779]	1	hSpCas9	negative selection	7394129
43586855	43586878	2	+	27260156	MHHES1	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.11488812628878586	[281]	[363,292,292,237]	-2	hSpCas9	negative selection	7394130
43586900	43586923	2	-	27260156	MHHES1	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.12258618189472703	[658]	[974,665,765,810]	2	hSpCas9	negative selection	7394131
43591984	43592007	2	-	27260156	MHHES1	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.06361996201392685	[522]	[962,525,571,289]	-1	hSpCas9	negative selection	7458383
43590888	43590911	2	-	27260156	MHHES1	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.8648091639528162	[483]	[1128,951,1020,883]	9	hSpCas9	negative selection	7458384
43591945	43591968	2	+	27260156	MHHES1	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.6225049513127401	[226]	[550,482,311,274]	9	hSpCas9	negative selection	7458385
43590939	43590962	2	-	27260156	MEWO	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.2667565528989479	[593]	[717,503,793]	6	hSpCas9	negative selection	7515380
43586855	43586878	2	+	27260156	MEWO	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	0.08318881670698408	[281]	[404,221,235]	1	hSpCas9	negative selection	7515381
43586900	43586923	2	-	27260156	MEWO	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.07351961588358047	[658]	[757,569,462]	-2	hSpCas9	negative selection	7515382
43591984	43592007	2	-	27260156	MEWO	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.06321409496583967	[522]	[500,507,401]	-1	hSpCas9	negative selection	7579634
43590888	43590911	2	-	27260156	MEWO	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.7697377251816853	[483]	[936,744,665]	9	hSpCas9	negative selection	7579635
43591945	43591968	2	+	27260156	MEWO	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.08795038798221555	[226]	[241,280,156]	2	hSpCas9	negative selection	7579636
43590939	43590962	2	-	27260156	LNCAPCLONEFGC	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.13752100098476489	[593]	[543,735,641,443]	2	hSpCas9	negative selection	7636631
43586855	43586878	2	+	27260156	LNCAPCLONEFGC	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.05478535360268788	[281]	[220,312,288,162]	-1	hSpCas9	negative selection	7636632
43586900	43586923	2	-	27260156	LNCAPCLONEFGC	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.3651910766766151	[658]	[804,658,898,737]	6	hSpCas9	negative selection	7636633
43591984	43592007	2	-	27260156	LNCAPCLONEFGC	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.026347744500044457	[522]	[503,468,495,394]	0	hSpCas9	negative selection	7700885
43590888	43590911	2	-	27260156	LNCAPCLONEFGC	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.8848428134013905	[483]	[743,589,1175,797]	9	hSpCas9	negative selection	7700886
43591945	43591968	2	+	27260156	LNCAPCLONEFGC	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.4293350004471357	[226]	[169,311,396,245]	6	hSpCas9	negative selection	7700887
43590939	43590962	2	-	27260156	PANC0327	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	-0.20435186155157528	[593]	[818,420,331,293]	-3	hSpCas9	negative selection	7757882
43586855	43586878	2	+	27260156	PANC0327	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.8051028235345156	[281]	[156,123,125,169]	-8	hSpCas9	negative selection	7757883
43586900	43586923	2	-	27260156	PANC0327	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.374742045590884	[658]	[995,744,649,665]	5	hSpCas9	negative selection	7757884
43591984	43592007	2	-	27260156	PANC0327	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.09305096397415458	[522]	[478,324,472,482]	-1	hSpCas9	negative selection	7822136
43590888	43590911	2	-	27260156	PANC0327	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.5901233630213707	[483]	[516,496,554,1027]	8	hSpCas9	negative selection	7822137
43591945	43591968	2	+	27260156	PANC0327	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.4896932976073741	[226]	[254,360,215,287]	7	hSpCas9	negative selection	7822138
43590939	43590962	2	-	27260156	NCIH2009	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.29681525306439355	[593]	[959,1017,1066]	4	hSpCas9	negative selection	7879133
43586855	43586878	2	+	27260156	NCIH2009	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.35876821486911614	[281]	[393,217,327]	-5	hSpCas9	negative selection	7879134
43586900	43586923	2	-	27260156	NCIH2009	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.3748446282621658	[658]	[1515,937,1193]	5	hSpCas9	negative selection	7879135
43591984	43592007	2	-	27260156	NCIH2009	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.0948176458643003	[522]	[824,648,605]	-1	hSpCas9	negative selection	7943387
43590888	43590911	2	-	27260156	NCIH2009	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.7799145917460444	[483]	[1204,1270,1011]	9	hSpCas9	negative selection	7943388
43591945	43591968	2	+	27260156	NCIH2009	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.42471320382877	[226]	[469,490,322]	6	hSpCas9	negative selection	7943389
43590939	43590962	2	-	27260156	NCIH1373	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.4957282542121874	[593]	[1429,696,589,303]	5	hSpCas9	negative selection	8000384
43586855	43586878	2	+	27260156	NCIH1373	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	0.36154808663777604	[281]	[765,216,513,48]	3	hSpCas9	negative selection	8000385
43586900	43586923	2	-	27260156	NCIH1373	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.6968698247770091	[658]	[1320,864,1451,313]	7	hSpCas9	negative selection	8000386
43591984	43592007	2	-	27260156	NCIH1373	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.4727893736423848	[522]	[496,264,385,151]	-5	hSpCas9	negative selection	8064638
43590888	43590911	2	-	27260156	NCIH1373	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	1.058980840526641	[483]	[948,878,1154,408]	9	hSpCas9	negative selection	8064639
43591945	43591968	2	+	27260156	NCIH1373	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	1.4151584804878206	[226]	[593,932,416,192]	9	hSpCas9	negative selection	8064640
43590939	43590962	2	-	27260156	PATU8902	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.203582594762514	[593]	[1443,862,547,1058]	2	hSpCas9	negative selection	8121635
43586855	43586878	2	+	27260156	PATU8902	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	0.4991374456065093	[281]	[853,555,306,559]	5	hSpCas9	negative selection	8121636
43586900	43586923	2	-	27260156	PATU8902	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.40306590190350544	[658]	[1618,746,1203,1277]	4	hSpCas9	negative selection	8121637
43591984	43592007	2	-	27260156	PATU8902	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.08940341086255181	[522]	[910,555,417,944]	-1	hSpCas9	negative selection	8185889
43590888	43590911	2	-	27260156	PATU8902	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.9903010870533323	[483]	[1473,1439,648,2044]	9	hSpCas9	negative selection	8185890
43591945	43591968	2	+	27260156	PATU8902	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.50516166003817	[226]	[674,294,234,663]	5	hSpCas9	negative selection	8185891
43590939	43590962	2	-	27260156	PANC1	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.13495869116499953	[593]	[618,626,569,446]	2	hSpCas9	negative selection	8242886
43586855	43586878	2	+	27260156	PANC1	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.16173212668064074	[281]	[203,261,196,209]	-3	hSpCas9	negative selection	8242887
43586900	43586923	2	-	27260156	PANC1	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.22397447086181133	[658]	[575,927,498,681]	3	hSpCas9	negative selection	8242888
43591984	43592007	2	-	27260156	PANC1	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.08264588255081864	[522]	[656,473,319,268]	-1	hSpCas9	negative selection	8307140
43590888	43590911	2	-	27260156	PANC1	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.5258018303565923	[483]	[696,638,474,580]	8	hSpCas9	negative selection	8307141
43591945	43591968	2	+	27260156	PANC1	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.47201315525542054	[226]	[271,441,217,192]	7	hSpCas9	negative selection	8307142
43590939	43590962	2	-	27260156	PANC0813	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	-0.12308850642230965	[593]	[592,745,613,605]	-2	hSpCas9	negative selection	8364137
43586855	43586878	2	+	27260156	PANC0813	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.23507673489761371	[281]	[252,271,421,181]	-4	hSpCas9	negative selection	8364138
43586900	43586923	2	-	27260156	PANC0813	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.28507206388492534	[658]	[937,916,750,1151]	4	hSpCas9	negative selection	8364139
43591984	43592007	2	-	27260156	PANC0813	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	0.04071373568951017	[522]	[609,617,805,498]	0	hSpCas9	negative selection	8428391
43590888	43590911	2	-	27260156	PANC0813	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.8135207380351862	[483]	[1011,865,880,1223]	9	hSpCas9	negative selection	8428392
43591945	43591968	2	+	27260156	PANC0813	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.6152841115150369	[226]	[433,426,291,477]	8	hSpCas9	negative selection	8428393
43590939	43590962	2	-	27260156	RDES	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.06354280714747274	[593]	[540,770,725,848]	1	hSpCas9	negative selection	8485388
43586855	43586878	2	+	27260156	RDES	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	0.026909471059848755	[281]	[221,341,305,487]	0	hSpCas9	negative selection	8485389
43586900	43586923	2	-	27260156	RDES	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.2875579823894655	[658]	[698,615,1058,1467]	4	hSpCas9	negative selection	8485390
43591984	43592007	2	-	27260156	RDES	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.17372149904545287	[522]	[397,513,571,689]	-3	hSpCas9	negative selection	8549642
43590888	43590911	2	-	27260156	RDES	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.8496329546888441	[483]	[786,1058,1007,1198]	9	hSpCas9	negative selection	8549643
43591945	43591968	2	+	27260156	RDES	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.6013187340700473	[226]	[314,325,414,567]	8	hSpCas9	negative selection	8549644
43590939	43590962	2	-	27260156	PC3	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	-0.15538262876232992	[593]	[397,502,683,602]	-3	hSpCas9	negative selection	8606639
43586855	43586878	2	+	27260156	PC3	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.30512640041968864	[281]	[158,122,423,295]	-6	hSpCas9	negative selection	8606640
43586900	43586923	2	-	27260156	PC3	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.0680473621573584	[658]	[411,511,1148,676]	-1	hSpCas9	negative selection	8606641
43591984	43592007	2	-	27260156	PC3	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.33289238720118997	[522]	[294,351,626,477]	-6	hSpCas9	negative selection	8670893
43590888	43590911	2	-	27260156	PC3	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.3050229320918426	[483]	[377,576,1063,584]	6	hSpCas9	negative selection	8670894
43591945	43591968	2	+	27260156	PC3	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.01905230606560826	[226]	[106,192,598,199]	0	hSpCas9	negative selection	8670895
43590939	43590962	2	-	27260156	PATU8988T	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.08287627909084444	[593]	[497,662,665,608]	1	hSpCas9	negative selection	8727890
43586855	43586878	2	+	27260156	PATU8988T	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	0.2116903834019651	[281]	[212,342,222,501]	3	hSpCas9	negative selection	8727891
43586900	43586923	2	-	27260156	PATU8988T	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.05738281802824918	[658]	[516,942,673,531]	1	hSpCas9	negative selection	8727892
43591984	43592007	2	-	27260156	PATU8988T	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.28597059264417	[522]	[393,313,416,532]	-5	hSpCas9	negative selection	8792144
43590888	43590911	2	-	27260156	PATU8988T	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.744591457310741	[483]	[768,709,895,747]	9	hSpCas9	negative selection	8792145
43591945	43591968	2	+	27260156	PATU8988T	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.1047629178873285	[226]	[384,156,140,255]	1	hSpCas9	negative selection	8792146
43590939	43590962	2	-	27260156	T47D	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.12007852214750064	[593]	[749,709,654,902]	2	hSpCas9	negative selection	8849141
43586855	43586878	2	+	27260156	T47D	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.01007871597333887	[281]	[340,331,299,331]	0	hSpCas9	negative selection	8849142
43586900	43586923	2	-	27260156	T47D	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.008679319237764882	[658]	[668,782,812,784]	0	hSpCas9	negative selection	8849143
43591984	43592007	2	-	27260156	T47D	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.014044628598169878	[522]	[656,487,663,613]	0	hSpCas9	negative selection	8913395
43590888	43590911	2	-	27260156	T47D	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.588586111704736	[483]	[885,811,921,770]	9	hSpCas9	negative selection	8913396
43591945	43591968	2	+	27260156	T47D	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.3584140640912522	[226]	[378,350,285,339]	7	hSpCas9	negative selection	8913397
43590939	43590962	2	-	27260156	SU8686	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.33575973843264834	[593]	[662,527,942,901]	5	hSpCas9	negative selection	8970392
43586855	43586878	2	+	27260156	SU8686	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.03909452963731519	[281]	[234,302,305,237]	0	hSpCas9	negative selection	8970393
43586900	43586923	2	-	27260156	SU8686	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.20804109246184943	[658]	[528,789,818,925]	3	hSpCas9	negative selection	8970394
43591984	43592007	2	-	27260156	SU8686	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	0.1640913382917252	[522]	[575,483,532,768]	2	hSpCas9	negative selection	9034646
43590888	43590911	2	-	27260156	SU8686	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.7461154317750472	[483]	[560,779,919,1021]	9	hSpCas9	negative selection	9034647
43591945	43591968	2	+	27260156	SU8686	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.5725014182650359	[226]	[224,242,440,477]	8	hSpCas9	negative selection	9034648
43590939	43590962	2	-	27260156	SKES1	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.03651199041636938	[593]	[851,508,529,561]	0	hSpCas9	negative selection	9091643
43586855	43586878	2	+	27260156	SKES1	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.2893375759565996	[281]	[178,334,268,149]	-6	hSpCas9	negative selection	9091644
43586900	43586923	2	-	27260156	SKES1	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.015995324533617294	[658]	[515,841,529,704]	0	hSpCas9	negative selection	9091645
43591984	43592007	2	-	27260156	SKES1	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.2106837079318933	[522]	[405,473,454,458]	-4	hSpCas9	negative selection	9155897
43590888	43590911	2	-	27260156	SKES1	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.7863676051507291	[483]	[848,872,724,877]	9	hSpCas9	negative selection	9155898
43591945	43591968	2	+	27260156	SKES1	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.11170319275273477	[226]	[280,276,184,242]	2	hSpCas9	negative selection	9155899
43590939	43590962	2	-	27260156	TOV112D	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.27607657804576763	[593]	[941,968,538,515]	5	hSpCas9	negative selection	9212894
43586855	43586878	2	+	27260156	TOV112D	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	0.3715903869111037	[281]	[516,396,289,279]	7	hSpCas9	negative selection	9212895
43586900	43586923	2	-	27260156	TOV112D	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.24018781559340496	[658]	[542,650,588,474]	-5	hSpCas9	negative selection	9212896
43591984	43592007	2	-	27260156	TOV112D	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	0.11632426475244365	[522]	[653,648,517,478]	2	hSpCas9	negative selection	9277148
43590888	43590911	2	-	27260156	TOV112D	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.6938323123356469	[483]	[947,817,776,618]	9	hSpCas9	negative selection	9277149
43591945	43591968	2	+	27260156	TOV112D	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.13671608207791897	[226]	[194,318,292,205]	2	hSpCas9	negative selection	9277150
43590939	43590962	2	-	27260156	TC71	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.053619416832148936	[593]	[554,613,708,772]	1	hSpCas9	negative selection	9334145
43586855	43586878	2	+	27260156	TC71	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.029127563413296365	[281]	[248,329,275,333]	0	hSpCas9	negative selection	9334146
43586900	43586923	2	-	27260156	TC71	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	-0.05850919636994406	[658]	[632,776,646,656]	-1	hSpCas9	negative selection	9334147
43591984	43592007	2	-	27260156	TC71	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.21034591887444753	[522]	[360,531,495,555]	-5	hSpCas9	negative selection	9398399
43590888	43590911	2	-	27260156	TC71	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.596476993998061	[483]	[958,676,736,760]	9	hSpCas9	negative selection	9398400
43591945	43591968	2	+	27260156	TC71	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.3347153126505763	[226]	[281,268,387,284]	7	hSpCas9	negative selection	9398401
43590939	43590962	2	-	27260156	TC32	viability	ATTATAGATTGTGCCTCTGCTGG	THADA	ENSG00000115970	0.07455764220805089	[593]	[573,394,736,718]	1	hSpCas9	negative selection	9455396
43586855	43586878	2	+	27260156	TC32	viability	CAAGTTAAAGTTCTCCATACAGG	THADA	ENSG00000115970	-0.17862521551358912	[281]	[250,135,279,302]	-3	hSpCas9	negative selection	9455397
43586900	43586923	2	-	27260156	TC32	viability	CTACTGACTTATACTCTTACAGG	THADA	ENSG00000115970	0.2425142205244939	[658]	[720,495,1049,768]	4	hSpCas9	negative selection	9455398
43591984	43592007	2	-	27260156	TC32	viability	GTTACATTGTGTGCAACTCACGG	THADA	ENSG00000115970	-0.14248745140429966	[522]	[388,313,627,516]	-3	hSpCas9	negative selection	9519650
43590888	43590911	2	-	27260156	TC32	viability	TCCCACTATTCAAAGTTGTTTGG	THADA	ENSG00000115970	0.7409646394402638	[483]	[767,569,954,808]	9	hSpCas9	negative selection	9519651
43591945	43591968	2	+	27260156	TC32	viability	GACTTACCTGTTTAATATAATGG	THADA	ENSG00000115970	0.639838352217356	[226]	[273,375,293,347]	9	hSpCas9	negative selection	9519652
43498907	43498930	2	-	27869803	HPAFII	viability after 27 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-0.9568041324055204	[145]	[62,19,NaN]	-6	hSpCas9	negative selection	9575053
43541278	43541301	2	-	27869803	HPAFII	viability after 27 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	0.5733035817904808	[204]	[197,128,NaN]	4	hSpCas9	negative selection	9575054
43551835	43551858	2	+	27869803	HPAFII	viability after 27 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.3826251554871175	[233]	[119,72,NaN]	-3	hSpCas9	negative selection	9575055
43556358	43556381	2	-	27869803	HPAFII	viability after 27 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.9000067056274418	[460]	[304,574,NaN]	7	hSpCas9	negative selection	9575056
43574836	43574859	2	+	27869803	HPAFII	viability after 27 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.6977397839615936	[144]	[16,71,NaN]	-5	hSpCas9	negative selection	9575057
43592327	43592350	2	+	27869803	HPAFII	viability after 27 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.12515229022211882	[484]	[306,253,NaN]	1	hSpCas9	negative selection	9575058
43498907	43498930	2	-	27869803	HPAFII	viability after 15 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-1.0710082057659678	[145]	[115,48,NaN]	-8	hSpCas9	negative selection	9657502
43541278	43541301	2	-	27869803	HPAFII	viability after 15 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	0.30513254841007625	[204]	[397,193,NaN]	3	hSpCas9	negative selection	9657503
43551835	43551858	2	+	27869803	HPAFII	viability after 15 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.2718542377081506	[233]	[330,131,NaN]	-3	hSpCas9	negative selection	9657504
43556358	43556381	2	-	27869803	HPAFII	viability after 15 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.8182621659485315	[460]	[1065,753,NaN]	8	hSpCas9	negative selection	9657505
43574836	43574859	2	+	27869803	HPAFII	viability after 15 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.7465071745474449	[144]	[111,80,NaN]	-7	hSpCas9	negative selection	9657506
43592327	43592350	2	+	27869803	HPAFII	viability after 15 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.0026180444469389164	[484]	[774,364,NaN]	0	hSpCas9	negative selection	9657507
43498907	43498930	2	-	27869803	ASPC1	viability after 36 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	0.280904087897341	[194]	[43,156,49]	3	hSpCas9	negative selection	9739951
43541278	43541301	2	-	27869803	ASPC1	viability after 36 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	-0.10746573038799323	[513]	[305,134,91]	-1	hSpCas9	negative selection	9739952
43551835	43551858	2	+	27869803	ASPC1	viability after 36 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.03312769802415061	[575]	[181,365,92]	0	hSpCas9	negative selection	9739953
43556358	43556381	2	-	27869803	ASPC1	viability after 36 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.7731582094884522	[1221]	[793,540,824]	7	hSpCas9	negative selection	9739954
43574836	43574859	2	+	27869803	ASPC1	viability after 36 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	0.5384926950899787	[343]	[222,72,218]	5	hSpCas9	negative selection	9739955
43592327	43592350	2	+	27869803	ASPC1	viability after 36 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.3134399559794132	[1123]	[606,500,387]	3	hSpCas9	negative selection	9739956
43498907	43498930	2	-	27869803	PATU8988S	viability after 35 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-0.5261346352116862	[219]	[73,48,NaN]	-5	hSpCas9	negative selection	9822400
43541278	43541301	2	-	27869803	PATU8988S	viability after 35 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	0.33047058017478137	[400]	[236,168,NaN]	4	hSpCas9	negative selection	9822401
43551835	43551858	2	+	27869803	PATU8988S	viability after 35 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.4554433743952496	[544]	[193,125,NaN]	-5	hSpCas9	negative selection	9822402
43556358	43556381	2	-	27869803	PATU8988S	viability after 35 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.831633736332043	[1103]	[930,650,NaN]	8	hSpCas9	negative selection	9822403
43574836	43574859	2	+	27869803	PATU8988S	viability after 35 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.4237737395738614	[404]	[163,78,NaN]	-4	hSpCas9	negative selection	9822404
43592327	43592350	2	+	27869803	PATU8988S	viability after 35 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.5976661956267072	[917]	[555,562,NaN]	6	hSpCas9	negative selection	9822405
43498907	43498930	2	-	27869803	PATU8988S	viability after 31 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-0.23442918939246993	[219]	[107,31,NaN]	-3	hSpCas9	negative selection	9904849
43541278	43541301	2	-	27869803	PATU8988S	viability after 31 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	0.2289614679427338	[400]	[171,206,NaN]	3	hSpCas9	negative selection	9904850
43551835	43551858	2	+	27869803	PATU8988S	viability after 31 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.5344558247211313	[544]	[142,158,NaN]	-5	hSpCas9	negative selection	9904851
43556358	43556381	2	-	27869803	PATU8988S	viability after 31 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.8405217040016368	[1103]	[632,985,NaN]	8	hSpCas9	negative selection	9904852
43574836	43574859	2	+	27869803	PATU8988S	viability after 31 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.5262920264645459	[404]	[156,54,NaN]	-5	hSpCas9	negative selection	9904853
43592327	43592350	2	+	27869803	PATU8988S	viability after 31 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.48962682942847413	[917]	[509,518,NaN]	6	hSpCas9	negative selection	9904854
43498907	43498930	2	-	27869803	HPAFII	viability after 35 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-2.04670871131076	[145]	[31,1,NaN]	-7	hSpCas9	negative selection	9987298
43541278	43541301	2	-	27869803	HPAFII	viability after 35 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	0.7574644623601003	[204]	[237,104,NaN]	5	hSpCas9	negative selection	9987299
43551835	43551858	2	+	27869803	HPAFII	viability after 35 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.6278725858622667	[233]	[102,46,NaN]	-4	hSpCas9	negative selection	9987300
43556358	43556381	2	-	27869803	HPAFII	viability after 35 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.8826924716396233	[460]	[339,531,NaN]	6	hSpCas9	negative selection	9987301
43574836	43574859	2	+	27869803	HPAFII	viability after 35 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.3535706606889698	[144]	[16,102,NaN]	-2	hSpCas9	negative selection	9987302
43592327	43592350	2	+	27869803	HPAFII	viability after 35 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.015914750997065963	[484]	[164,341,NaN]	0	hSpCas9	negative selection	9987303
43498907	43498930	2	-	27869803	HPAFII	viability after 31 days	ATTGTTCAGAGATACGCGCCTGG	THADA	ENSG00000115970	-2.847300462159254	[145]	[19,1,NaN]	-8	hSpCas9	negative selection	10069747
43541278	43541301	2	-	27869803	HPAFII	viability after 31 days	ATGTGATGTAACTGCGCAGATGG	THADA	ENSG00000115970	1.0171924272306474	[204]	[318,138,NaN]	7	hSpCas9	negative selection	10069748
43551835	43551858	2	+	27869803	HPAFII	viability after 31 days	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.19024949666327884	[233]	[161,63,NaN]	-1	hSpCas9	negative selection	10069749
43556358	43556381	2	-	27869803	HPAFII	viability after 31 days	GGCCTGCTGCTGTGGTGGAAAGG	THADA	ENSG00000115970	0.9902525120092859	[460]	[378,660,NaN]	7	hSpCas9	negative selection	10069750
43574836	43574859	2	+	27869803	HPAFII	viability after 31 days	TGGTGTCTCAGAGCATCCAATGG	THADA	ENSG00000115970	-0.8140428095126563	[144]	[7,87,NaN]	-5	hSpCas9	negative selection	10069751
43592327	43592350	2	+	27869803	HPAFII	viability after 31 days	TTCAAGGTCCTGATGGCAAATGG	THADA	ENSG00000115970	0.03520828204948523	[484]	[209,353,NaN]	0	hSpCas9	negative selection	10069752
43577149	43577172	2	+	28162770	P31FUJ	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	-0.057715497856287434	[154]	[174]	0	hSpCas9	negative selection	10250086
43574796	43574819	2	-	28162770	P31FUJ	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	-0.5984516767310588	[66]	[51]	-5	hSpCas9	negative selection	10250087
43577083	43577106	2	-	28162770	P31FUJ	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.6141000928005883	[292]	[526]	7	hSpCas9	negative selection	10250088
43574499	43574522	2	-	28162770	P31FUJ	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	-0.4428374192308437	[154]	[133]	-4	hSpCas9	negative selection	10250089
43551835	43551858	2	+	28162770	P31FUJ	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.0799852366165148	[284]	[353]	0	hSpCas9	negative selection	10250090
43428152	43428175	2	-	28162770	P31FUJ	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	0.4192744921653144	[48]	[76]	5	hSpCas9	negative selection	10250091
43292123	43292146	2	-	28162770	P31FUJ	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	0.9987891537685342	[200]	[471]	9	hSpCas9	negative selection	10250092
43287026	43287049	2	-	28162770	P31FUJ	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	0.9622137779907642	[227]	[521]	9	hSpCas9	negative selection	10250093
43286948	43286971	2	+	28162770	P31FUJ	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	-0.4519194937179656	[219]	[188]	-4	hSpCas9	negative selection	10250094
43591980	43592003	2	-	28162770	P31FUJ	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.6885234814577088	[178]	[338]	7	hSpCas9	negative selection	10250095
43577149	43577172	2	+	28162770	TF1	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10419452
43574796	43574819	2	-	28162770	TF1	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	NaN	[NaN]	[104]	1	hSpCas9	negative selection	10419453
43577083	43577106	2	-	28162770	TF1	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	NaN	[NaN]	[340]	1	hSpCas9	negative selection	10419454
43574499	43574522	2	-	28162770	TF1	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10419455
43551835	43551858	2	+	28162770	TF1	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	NaN	[NaN]	[277]	1	hSpCas9	negative selection	10419456
43428152	43428175	2	-	28162770	TF1	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10419457
43292123	43292146	2	-	28162770	TF1	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	NaN	[NaN]	[203]	1	hSpCas9	negative selection	10419458
43287026	43287049	2	-	28162770	TF1	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	NaN	[NaN]	[157]	1	hSpCas9	negative selection	10419459
43286948	43286971	2	+	28162770	TF1	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10419460
43591980	43592003	2	-	28162770	TF1	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10419461
43577149	43577172	2	+	28162770	SKM1	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	-0.9081583417717201	[68]	[64]	-6	hSpCas9	negative selection	10588818
43574796	43574819	2	-	28162770	SKM1	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	1.3796321631476447	[4]	[22]	9	hSpCas9	negative selection	10588819
43577083	43577106	2	-	28162770	SKM1	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.16702718415699136	[65]	[130]	1	hSpCas9	negative selection	10588820
43574499	43574522	2	-	28162770	SKM1	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	0.6340630695168932	[38]	[106]	6	hSpCas9	negative selection	10588821
43551835	43551858	2	+	28162770	SKM1	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.7871068900308531	[78]	[240]	7	hSpCas9	negative selection	10588822
43428152	43428175	2	-	28162770	SKM1	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	-0.5382087320214142	[22]	[27]	-4	hSpCas9	negative selection	10588823
43292123	43292146	2	-	28162770	SKM1	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	-0.5390677347505068	[59]	[72]	-4	hSpCas9	negative selection	10588824
43287026	43287049	2	-	28162770	SKM1	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	1.2725159007622844	[47]	[204]	9	hSpCas9	negative selection	10588825
43286948	43286971	2	+	28162770	SKM1	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	0.5334789565763836	[33]	[86]	5	hSpCas9	negative selection	10588826
43591980	43592003	2	-	28162770	SKM1	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.13735631748064858	[35]	[69]	1	hSpCas9	negative selection	10588827
43577149	43577172	2	+	28162770	SKM1	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	-0.9081583417717201	[68]	[64]	-6	hSpCas9	negative selection	10758184
43574796	43574819	2	-	28162770	SKM1	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	1.3796321631476447	[4]	[22]	9	hSpCas9	negative selection	10758185
43577083	43577106	2	-	28162770	SKM1	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.16702718415699136	[65]	[130]	1	hSpCas9	negative selection	10758186
43574499	43574522	2	-	28162770	SKM1	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	0.6340630695168932	[38]	[106]	6	hSpCas9	negative selection	10758187
43551835	43551858	2	+	28162770	SKM1	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.7871068900308531	[78]	[240]	7	hSpCas9	negative selection	10758188
43428152	43428175	2	-	28162770	SKM1	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	-0.5382087320214142	[22]	[27]	-4	hSpCas9	negative selection	10758189
43292123	43292146	2	-	28162770	SKM1	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	-0.5390677347505068	[59]	[72]	-4	hSpCas9	negative selection	10758190
43287026	43287049	2	-	28162770	SKM1	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	1.2725159007622844	[47]	[204]	9	hSpCas9	negative selection	10758191
43286948	43286971	2	+	28162770	SKM1	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	0.5334789565763836	[33]	[86]	5	hSpCas9	negative selection	10758192
43591980	43592003	2	-	28162770	SKM1	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.13735631748064858	[35]	[69]	1	hSpCas9	negative selection	10758193
43577149	43577172	2	+	28162770	PL21	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	0.20013961448932016	[201]	[100]	1	hSpCas9	negative selection	10927550
43574796	43574819	2	-	28162770	PL21	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	-3.9697853869529927	[35]	[0]	-9	hSpCas9	negative selection	10927551
43577083	43577106	2	-	28162770	PL21	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.2594367981730923	[285]	[148]	2	hSpCas9	negative selection	10927552
43574499	43574522	2	-	28162770	PL21	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	0.0258886876442177	[166]	[73]	0	hSpCas9	negative selection	10927553
43551835	43551858	2	+	28162770	PL21	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.5701021345511846	[306]	[89]	-4	hSpCas9	negative selection	10927554
43428152	43428175	2	-	28162770	PL21	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	-0.2550550112615062	[84]	[30]	-2	hSpCas9	negative selection	10927555
43292123	43292146	2	-	28162770	PL21	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	0.41992082236923023	[157]	[91]	3	hSpCas9	negative selection	10927556
43287026	43287049	2	-	28162770	PL21	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	0.21701343305371618	[169]	[85]	2	hSpCas9	negative selection	10927557
43286948	43286971	2	+	28162770	PL21	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	-0.014873276481530251	[129]	[55]	0	hSpCas9	negative selection	10927558
43591980	43592003	2	-	28162770	PL21	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	-0.2852872126809216	[125]	[44]	-2	hSpCas9	negative selection	10927559
43577149	43577172	2	+	28162770	P31FUJ	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	-0.057715497856287434	[154]	[174]	0	hSpCas9	negative selection	11096916
43574796	43574819	2	-	28162770	P31FUJ	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	-0.5984516767310588	[66]	[51]	-5	hSpCas9	negative selection	11096917
43577083	43577106	2	-	28162770	P31FUJ	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.6141000928005883	[292]	[526]	7	hSpCas9	negative selection	11096918
43574499	43574522	2	-	28162770	P31FUJ	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	-0.4428374192308437	[154]	[133]	-4	hSpCas9	negative selection	11096919
43551835	43551858	2	+	28162770	P31FUJ	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.0799852366165148	[284]	[353]	0	hSpCas9	negative selection	11096920
43428152	43428175	2	-	28162770	P31FUJ	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	0.4192744921653144	[48]	[76]	5	hSpCas9	negative selection	11096921
43292123	43292146	2	-	28162770	P31FUJ	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	0.9987891537685342	[200]	[471]	9	hSpCas9	negative selection	11096922
43287026	43287049	2	-	28162770	P31FUJ	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	0.9622137779907642	[227]	[521]	9	hSpCas9	negative selection	11096923
43286948	43286971	2	+	28162770	P31FUJ	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	-0.4519194937179656	[219]	[188]	-4	hSpCas9	negative selection	11096924
43591980	43592003	2	-	28162770	P31FUJ	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.6885234814577088	[178]	[338]	7	hSpCas9	negative selection	11096925
43577149	43577172	2	+	28162770	OCIAML5	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	0.234442422390678	[88]	[188]	2	hSpCas9	negative selection	11266282
43574796	43574819	2	-	28162770	OCIAML5	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	0.27226156413820446	[49]	[108]	2	hSpCas9	negative selection	11266283
43577083	43577106	2	-	28162770	OCIAML5	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.5616822324462744	[139]	[372]	5	hSpCas9	negative selection	11266284
43574499	43574522	2	-	28162770	OCIAML5	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	0.4361783977670767	[51]	[126]	4	hSpCas9	negative selection	11266285
43551835	43551858	2	+	28162770	OCIAML5	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.16703711503891838	[180]	[290]	-1	hSpCas9	negative selection	11266286
43428152	43428175	2	-	28162770	OCIAML5	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	0.947634778650172	[26]	[93]	7	hSpCas9	negative selection	11266287
43292123	43292146	2	-	28162770	OCIAML5	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	0.5783461543017628	[104]	[282]	5	hSpCas9	negative selection	11266288
43287026	43287049	2	-	28162770	OCIAML5	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	-0.19671474225144275	[119]	[188]	-1	hSpCas9	negative selection	11266289
43286948	43286971	2	+	28162770	OCIAML5	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	0.8602752363333868	[64]	[212]	7	hSpCas9	negative selection	11266290
43591980	43592003	2	-	28162770	OCIAML5	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.7894794582235268	[99]	[311]	7	hSpCas9	negative selection	11266291
43577149	43577172	2	+	28162770	EOL1	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	-0.11571609864319252	[326]	[158]	-1	hSpCas9	negative selection	11435648
43574796	43574819	2	-	28162770	EOL1	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	-0.8828071504870691	[62]	[17]	-6	hSpCas9	negative selection	11435649
43577083	43577106	2	-	28162770	EOL1	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	-0.8684232323244137	[498]	[143]	-6	hSpCas9	negative selection	11435650
43574499	43574522	2	-	28162770	EOL1	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	0.6973140871645874	[198]	[169]	6	hSpCas9	negative selection	11435651
43551835	43551858	2	+	28162770	EOL1	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.8923238015847957	[497]	[486]	7	hSpCas9	negative selection	11435652
43428152	43428175	2	-	28162770	EOL1	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	0.9007010296161668	[121]	[119]	7	hSpCas9	negative selection	11435653
43292123	43292146	2	-	28162770	EOL1	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	0.1135815959605514	[199]	[113]	1	hSpCas9	negative selection	11435654
43287026	43287049	2	-	28162770	EOL1	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	-0.08155242796588319	[236]	[117]	0	hSpCas9	negative selection	11435655
43286948	43286971	2	+	28162770	EOL1	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	-0.41476240154506416	[166]	[65]	-3	hSpCas9	negative selection	11435656
43591980	43592003	2	-	28162770	EOL1	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.8827275958759075	[174]	[169]	7	hSpCas9	negative selection	11435657
43577149	43577172	2	+	28162770	MOLM13	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	0.44014439106167447	[314]	[308]	3	hSpCas9	negative selection	11605014
43574796	43574819	2	-	28162770	MOLM13	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	-0.6531260194167872	[86]	[39]	-4	hSpCas9	negative selection	11605015
43577083	43577106	2	-	28162770	MOLM13	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.42151941840654494	[410]	[397]	3	hSpCas9	negative selection	11605016
43574499	43574522	2	-	28162770	MOLM13	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	-0.014262313592801723	[175]	[125]	0	hSpCas9	negative selection	11605017
43551835	43551858	2	+	28162770	MOLM13	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	1.2606567673791367	[354]	[614]	8	hSpCas9	negative selection	11605018
43428152	43428175	2	-	28162770	MOLM13	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	-0.17596680823014588	[149]	[95]	-1	hSpCas9	negative selection	11605019
43292123	43292146	2	-	28162770	MOLM13	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	0.20957738595318817	[304]	[254]	1	hSpCas9	negative selection	11605020
43287026	43287049	2	-	28162770	MOLM13	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	-0.28472947693311274	[277]	[164]	-2	hSpCas9	negative selection	11605021
43286948	43286971	2	+	28162770	MOLM13	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	-0.9588110352598451	[206]	[76]	-5	hSpCas9	negative selection	11605022
43591980	43592003	2	-	28162770	MOLM13	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	-0.6232585065136165	[195]	[91]	-4	hSpCas9	negative selection	11605023
43577149	43577172	2	+	28162770	HEL	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	0.25771390178795256	[221]	[169]	2	hSpCas9	negative selection	11774380
43574796	43574819	2	-	28162770	HEL	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	-1.5416857391370704	[49]	[10]	-7	hSpCas9	negative selection	11774381
43577083	43577106	2	-	28162770	HEL	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.38385606943703043	[346]	[289]	3	hSpCas9	negative selection	11774382
43574499	43574522	2	-	28162770	HEL	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	0.2472541301429137	[170]	[129]	2	hSpCas9	negative selection	11774383
43551835	43551858	2	+	28162770	HEL	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.38051698323726224	[354]	[295]	3	hSpCas9	negative selection	11774384
43428152	43428175	2	-	28162770	HEL	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	0.7895802203296282	[139]	[154]	6	hSpCas9	negative selection	11774385
43292123	43292146	2	-	28162770	HEL	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	0.07624899135067967	[193]	[130]	0	hSpCas9	negative selection	11774386
43287026	43287049	2	-	28162770	HEL	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	0.03701777111240348	[209]	[137]	0	hSpCas9	negative selection	11774387
43286948	43286971	2	+	28162770	HEL	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	-0.002166209177081213	[171]	[109]	0	hSpCas9	negative selection	11774388
43591980	43592003	2	-	28162770	HEL	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	-0.1646160900572473	[174]	[99]	-1	hSpCas9	negative selection	11774389
43577149	43577172	2	+	28162770	MV411	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	0.6367649309557242	[183]	[240]	6	hSpCas9	negative selection	11943746
43574796	43574819	2	-	28162770	MV411	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	0.40613529680183347	[42]	[47]	3	hSpCas9	negative selection	11943747
43577083	43577106	2	-	28162770	MV411	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.3042439064012483	[248]	[258]	2	hSpCas9	negative selection	11943748
43574499	43574522	2	-	28162770	MV411	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	-0.05681951777753147	[141]	[114]	0	hSpCas9	negative selection	11943749
43551835	43551858	2	+	28162770	MV411	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	-0.3176253925006762	[215]	[145]	-2	hSpCas9	negative selection	11943750
43428152	43428175	2	-	28162770	MV411	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	0.5230719933962026	[75]	[91]	5	hSpCas9	negative selection	11943751
43292123	43292146	2	-	28162770	MV411	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	-0.05100219118221704	[197]	[160]	0	hSpCas9	negative selection	11943752
43287026	43287049	2	-	28162770	MV411	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	0.7674446096631616	[158]	[227]	7	hSpCas9	negative selection	11943753
43286948	43286971	2	+	28162770	MV411	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	-0.36553932610797757	[129]	[84]	-3	hSpCas9	negative selection	11943754
43591980	43592003	2	-	28162770	MV411	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.4884456502865704	[98]	[116]	4	hSpCas9	negative selection	11943755
43577149	43577172	2	+	28162770	MONOMAC1	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	0.8176099289048476	[146]	[296]	7	hSpCas9	negative selection	12113112
43574796	43574819	2	-	28162770	MONOMAC1	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	1.533356093183166	[21]	[72]	9	hSpCas9	negative selection	12113113
43577083	43577106	2	-	28162770	MONOMAC1	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	-0.3105657926899679	[184]	[170]	-3	hSpCas9	negative selection	12113114
43574499	43574522	2	-	28162770	MONOMAC1	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	0.7881661510123659	[97]	[193]	7	hSpCas9	negative selection	12113115
43551835	43551858	2	+	28162770	MONOMAC1	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.7075059936925423	[163]	[306]	6	hSpCas9	negative selection	12113116
43428152	43428175	2	-	28162770	MONOMAC1	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	0.5191701869398548	[41]	[68]	5	hSpCas9	negative selection	12113117
43292123	43292146	2	-	28162770	MONOMAC1	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	-0.35354133273954436	[106]	[95]	-3	hSpCas9	negative selection	12113118
43287026	43287049	2	-	28162770	MONOMAC1	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	0.23906226774711975	[84]	[114]	2	hSpCas9	negative selection	12113119
43286948	43286971	2	+	28162770	MONOMAC1	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	0.5534435535811341	[84]	[142]	5	hSpCas9	negative selection	12113120
43591980	43592003	2	-	28162770	MONOMAC1	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.5399287471066523	[68]	[114]	5	hSpCas9	negative selection	12113121
43577149	43577172	2	+	28162770	OCIAML2	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	0.8475943008817823	[38]	[388]	7	hSpCas9	negative selection	12282478
43574796	43574819	2	-	28162770	OCIAML2	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	0.8512982696452014	[8]	[89]	8	hSpCas9	negative selection	12282479
43577083	43577106	2	-	28162770	OCIAML2	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.5954593652156113	[71]	[602]	6	hSpCas9	negative selection	12282480
43574499	43574522	2	-	28162770	OCIAML2	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	-1.1668490770650581	[31]	[78]	-6	hSpCas9	negative selection	12282481
43551835	43551858	2	+	28162770	OCIAML2	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.6324636677219423	[53]	[463]	6	hSpCas9	negative selection	12282482
43428152	43428175	2	-	28162770	OCIAML2	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	-0.25912572004844947	[18]	[87]	-2	hSpCas9	negative selection	12282483
43292123	43292146	2	-	28162770	OCIAML2	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	-0.37798053727648667	[48]	[208]	-3	hSpCas9	negative selection	12282484
43287026	43287049	2	-	28162770	OCIAML2	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	-0.02037763337925963	[42]	[234]	0	hSpCas9	negative selection	12282485
43286948	43286971	2	+	28162770	OCIAML2	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	1.1226002914625954	[28]	[349]	9	hSpCas9	negative selection	12282486
43591980	43592003	2	-	28162770	OCIAML2	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	0.5379321882612629	[20]	[168]	5	hSpCas9	negative selection	12282487
43577149	43577172	2	+	28162770	OCIAML3	viability	GAGAGATGTCACCACAACAGAGG	THADA	ENSG00000115970	0.31957760785836353	[42]	[161]	3	hSpCas9	negative selection	12451844
43574796	43574819	2	-	28162770	OCIAML3	viability	AAAACCTTCTCCAAATGCACCGG	THADA	ENSG00000115970	-0.5467019255458065	[14]	[30]	-4	hSpCas9	negative selection	12451845
43577083	43577106	2	-	28162770	OCIAML3	viability	GGACTGGCAGAACGGAAGCATGG	THADA	ENSG00000115970	0.6366713921972456	[61]	[290]	6	hSpCas9	negative selection	12451846
43574499	43574522	2	-	28162770	OCIAML3	viability	AGAGTTCTTGGATTGACCAGTGG	THADA	ENSG00000115970	-0.21213700498051868	[32]	[85]	-2	hSpCas9	negative selection	12451847
43551835	43551858	2	+	28162770	OCIAML3	viability	AATGACTGGAGACACCACAGTGG	THADA	ENSG00000115970	0.17537943153442054	[65]	[224]	1	hSpCas9	negative selection	12451848
43428152	43428175	2	-	28162770	OCIAML3	viability	GAGACTCTACGCTTCCCCGATGG	THADA	ENSG00000115970	0.5918589049871706	[19]	[90]	5	hSpCas9	negative selection	12451849
43292123	43292146	2	-	28162770	OCIAML3	viability	GGAGTTCTTGATCTGGACGATGG	THADA	ENSG00000115970	-0.31389972113142783	[48]	[118]	-2	hSpCas9	negative selection	12451850
43287026	43287049	2	-	28162770	OCIAML3	viability	TAGCTGCTGAGCTGAAGCAGTGG	THADA	ENSG00000115970	1.085282242945146	[36]	[236]	8	hSpCas9	negative selection	12451851
43286948	43286971	2	+	28162770	OCIAML3	viability	ACTGGTGAGGACTTCAACGACGG	THADA	ENSG00000115970	-1.5047403022270758	[46]	[49]	-8	hSpCas9	negative selection	12451852
43591980	43592003	2	-	28162770	OCIAML3	viability	CATTGTGTGCAACTCACGGATGG	THADA	ENSG00000115970	-0.6581379777438787	[45]	[87]	-5	hSpCas9	negative selection	12451853