Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7056
• Symbol:THBD
• Description:thrombomodulin

DataSource: http://genomecrispr.dkfz.de/#!/results/THBD

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
23049344	23049367	20	-	26472758	Jiyoye	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.06538686425766807	[127]	[100]	0	hSpCas9	negative selection	165046
23049171	23049194	20	+	26472758	Jiyoye	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	1.0238467419543678	[74]	[114]	6	hSpCas9	negative selection	165047
23049228	23049251	20	+	26472758	Jiyoye	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.14038884081097197	[153]	[127]	1	hSpCas9	negative selection	165048
23049061	23049084	20	+	26472758	Jiyoye	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-0.24490131507381974	[43]	[27]	-2	hSpCas9	negative selection	165049
23049021	23049044	20	-	26472758	Jiyoye	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	1.2967513918122229	[94]	[175]	7	hSpCas9	negative selection	165050
23048923	23048946	20	+	26472758	Jiyoye	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	-0.5720660583273289	[68]	[34]	-4	hSpCas9	negative selection	165051
23048613	23048636	20	+	26472758	Jiyoye	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	0.75509868492618	[32]	[41]	5	hSpCas9	negative selection	165052
23048474	23048497	20	+	26472758	Jiyoye	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.44309495576081603	[237]	[243]	3	hSpCas9	negative selection	165053
23048042	23048065	20	-	26472758	Jiyoye	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-1.7627496199364392	[35]	[7]	-8	hSpCas9	negative selection	165054
23049306	23049329	20	-	26472758	Jiyoye	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	-0.27762238679507756	[343]	[213]	-2	hSpCas9	negative selection	165055
23049344	23049367	20	-	26472758	KBM7	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.4659732907972604	[567,386]	[397,222]	5	hSpCas9	negative selection	356164
23049171	23049194	20	+	26472758	KBM7	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	0.3451998755281561	[194,189]	[126,104]	3	hSpCas9	negative selection	356165
23049228	23049251	20	+	26472758	KBM7	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.35648305162252986	[641,539]	[356,351]	4	hSpCas9	negative selection	356166
23049061	23049084	20	+	26472758	KBM7	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-0.18182390142304627	[194,107]	[112,14]	-2	hSpCas9	negative selection	356167
23049021	23049044	20	-	26472758	KBM7	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	0.16663469415175175	[655,489]	[442,170]	1	hSpCas9	negative selection	356168
23048923	23048946	20	+	26472758	KBM7	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	0.23571524591126525	[181,141]	[107,71]	2	hSpCas9	negative selection	356169
23048613	23048636	20	+	26472758	KBM7	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	0.923789134883177	[219,203]	[230,151]	8	hSpCas9	negative selection	356170
23048474	23048497	20	+	26472758	KBM7	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.45776436244857455	[1039,941]	[510,754]	5	hSpCas9	negative selection	356171
23048042	23048065	20	-	26472758	KBM7	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-0.18106374311988827	[31,34]	[22,5]	-2	hSpCas9	negative selection	356172
23049306	23049329	20	-	26472758	KBM7	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.36999461344937035	[1111,691]	[495,574]	4	hSpCas9	negative selection	356173
23049344	23049367	20	-	26472758	Raji	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.9425295234787091	[212]	[94]	8	hSpCas9	negative selection	547282
23049171	23049194	20	+	26472758	Raji	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	1.3758723712995014	[87]	[52]	9	hSpCas9	negative selection	547283
23049228	23049251	20	+	26472758	Raji	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.1005943697109604	[212]	[52]	0	hSpCas9	negative selection	547284
23049061	23049084	20	+	26472758	Raji	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-1.0942503257960512	[45]	[4]	-7	hSpCas9	negative selection	547285
23049021	23049044	20	-	26472758	Raji	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	0.7180561552006507	[240]	[91]	6	hSpCas9	negative selection	547286
23048923	23048946	20	+	26472758	Raji	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	0.46995361475830766	[83]	[26]	4	hSpCas9	negative selection	547287
23048613	23048636	20	+	26472758	Raji	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	0.6293362385689552	[194]	[69]	6	hSpCas9	negative selection	547288
23048474	23048497	20	+	26472758	Raji	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.6518840397507076	[457]	[166]	6	hSpCas9	negative selection	547289
23048042	23048065	20	-	26472758	Raji	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	0.5224210346524432	[14]	[4]	5	hSpCas9	negative selection	547290
23049306	23049329	20	-	26472758	Raji	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.18475209076191668	[598]	[157]	1	hSpCas9	negative selection	547291
23049344	23049367	20	-	26472758	K562	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.1593372267766788	[453]	[427]	1	hSpCas9	negative selection	738400
23049171	23049194	20	+	26472758	K562	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	1.0120560175750708	[120]	[205]	8	hSpCas9	negative selection	738401
23049228	23049251	20	+	26472758	K562	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	-0.617829841539295	[528]	[290]	-4	hSpCas9	negative selection	738402
23049061	23049084	20	+	26472758	K562	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-1.9255062737758655	[224]	[49]	-7	hSpCas9	negative selection	738403
23049021	23049044	20	-	26472758	K562	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	1.0497556118500482	[510]	[892]	8	hSpCas9	negative selection	738404
23048923	23048946	20	+	26472758	K562	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	-0.7924180405139245	[118]	[57]	-5	hSpCas9	negative selection	738405
23048613	23048636	20	+	26472758	K562	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	0.1560628532456002	[201]	[189]	1	hSpCas9	negative selection	738406
23048474	23048497	20	+	26472758	K562	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.4143437291087593	[783]	[881]	3	hSpCas9	negative selection	738407
23048042	23048065	20	-	26472758	K562	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-0.09261625961112419	[23]	[18]	0	hSpCas9	negative selection	738408
23049306	23049329	20	-	26472758	K562	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.7648409761928923	[639]	[917]	6	hSpCas9	negative selection	738409
23048049	23048072	20	-	26627737	DLD1	viability	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.14045866043394373	[3162]	[895,1405,995]	1	hSpCas9	negative selection	813604
23048327	23048350	20	-	26627737	DLD1	viability	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	-0.509904274877344	[300]	[53,108,40]	-5	hSpCas9	negative selection	813605
23048520	23048543	20	+	26627737	DLD1	viability	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.021493953441457325	[1303]	[352,447,437]	0	hSpCas9	negative selection	813606
23048834	23048857	20	+	26627737	DLD1	viability	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.6281314761497532	[454]	[233,397,59]	6	hSpCas9	negative selection	813607
23049081	23049104	20	+	26627737	DLD1	viability	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	-0.24957414495878782	[1854]	[627,493,360]	-3	hSpCas9	negative selection	813608
23048049	23048072	20	-	26627737	GBM cells	viability after 5 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.07228892589776459	[1252]	[743,668]	1	hSpCas9	negative selection	895919
23048327	23048350	20	-	26627737	GBM cells	viability after 5 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.3660398853129836	[135]	[79,107]	5	hSpCas9	negative selection	895920
23048520	23048543	20	+	26627737	GBM cells	viability after 5 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.02662504307423008	[550]	[356,244]	0	hSpCas9	negative selection	895921
23048834	23048857	20	+	26627737	GBM cells	viability after 5 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.5869698685709454	[359]	[294,284]	8	hSpCas9	negative selection	895922
23049081	23049104	20	+	26627737	GBM cells	viability after 5 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.5158011430030787	[580]	[462,427]	7	hSpCas9	negative selection	895923
23048049	23048072	20	-	26627737	GBM cells	viability after 13 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.09019211205461986	[1252]	[833,633]	1	hSpCas9	negative selection	978234
23048327	23048350	20	-	26627737	GBM cells	viability after 13 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.40088218030305506	[135]	[124,74]	5	hSpCas9	negative selection	978235
23048520	23048543	20	+	26627737	GBM cells	viability after 13 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.28838315025466255	[550]	[454,291]	3	hSpCas9	negative selection	978236
23048834	23048857	20	+	26627737	GBM cells	viability after 13 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.27154396485036125	[359]	[280,198]	3	hSpCas9	negative selection	978237
23049081	23049104	20	+	26627737	GBM cells	viability after 13 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.4291795688075384	[580]	[590,288]	5	hSpCas9	negative selection	978238
23048049	23048072	20	-	26627737	GBM cells	viability after 21 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.18129121352884603	[1252]	[809,736]	2	hSpCas9	negative selection	1060549
23048327	23048350	20	-	26627737	GBM cells	viability after 21 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.5476579605287877	[135]	[107,107]	5	hSpCas9	negative selection	1060550
23048520	23048543	20	+	26627737	GBM cells	viability after 21 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	-0.5666703827463252	[550]	[222,182]	-5	hSpCas9	negative selection	1060551
23048834	23048857	20	+	26627737	GBM cells	viability after 21 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.40994629634888335	[359]	[274,245]	4	hSpCas9	negative selection	1060552
23049081	23049104	20	+	26627737	GBM cells	viability after 21 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.15526542895804996	[580]	[362,340]	1	hSpCas9	negative selection	1060553
23048049	23048072	20	-	26627737	RPE1	viability after 9 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	-0.09790648271263791	[6155]	[1454,2246]	0	hSpCas9	negative selection	1142864
23048327	23048350	20	-	26627737	RPE1	viability after 9 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	-0.6349822605791124	[439]	[127,37]	-4	hSpCas9	negative selection	1142865
23048520	23048543	20	+	26627737	RPE1	viability after 9 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.5696415934303386	[1160]	[328,810]	4	hSpCas9	negative selection	1142866
23048834	23048857	20	+	26627737	RPE1	viability after 9 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.6419144485426251	[1108]	[484,614]	4	hSpCas9	negative selection	1142867
23049081	23049104	20	+	26627737	RPE1	viability after 9 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.8569273259439929	[1785]	[896,1161]	5	hSpCas9	negative selection	1142868
23048049	23048072	20	-	26627737	RPE1	viability after 12 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.07684907553917109	[6155]	[1570,1927]	0	hSpCas9	negative selection	1225179
23048327	23048350	20	-	26627737	RPE1	viability after 12 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	-0.09790539658525266	[439]	[108,111]	0	hSpCas9	negative selection	1225180
23048520	23048543	20	+	26627737	RPE1	viability after 12 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.6134093876154371	[1160]	[381,577]	4	hSpCas9	negative selection	1225181
23048834	23048857	20	+	26627737	RPE1	viability after 12 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	1.0675265128565516	[1108]	[860,373]	6	hSpCas9	negative selection	1225182
23049081	23049104	20	+	26627737	RPE1	viability after 12 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.8126415504818585	[1785]	[733,957]	5	hSpCas9	negative selection	1225183
23048049	23048072	20	-	26627737	RPE1	viability after 15 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	-0.09362730080158022	[6155]	[1520,1738]	0	hSpCas9	negative selection	1307494
23048327	23048350	20	-	26627737	RPE1	viability after 15 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.091714998133267	[439]	[124,139]	0	hSpCas9	negative selection	1307495
23048520	23048543	20	+	26627737	RPE1	viability after 15 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.7719647651570941	[1160]	[458,658]	5	hSpCas9	negative selection	1307496
23048834	23048857	20	+	26627737	RPE1	viability after 15 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	1.646586876229906	[1108]	[1504,477]	8	hSpCas9	negative selection	1307497
23049081	23049104	20	+	26627737	RPE1	viability after 15 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	1.1691778691232635	[1785]	[1042,1225]	6	hSpCas9	negative selection	1307498
23048049	23048072	20	-	26627737	RPE1	viability after 18 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	-0.1484066943588509	[6155]	[1204,1812]	-1	hSpCas9	negative selection	1389809
23048327	23048350	20	-	26627737	RPE1	viability after 18 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	-0.14060752594156112	[439]	[113,100]	-1	hSpCas9	negative selection	1389810
23048520	23048543	20	+	26627737	RPE1	viability after 18 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.30871077322443974	[1160]	[331,447]	2	hSpCas9	negative selection	1389811
23048834	23048857	20	+	26627737	RPE1	viability after 18 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	1.9771894900373397	[1108]	[1931,372]	8	hSpCas9	negative selection	1389812
23049081	23049104	20	+	26627737	RPE1	viability after 18 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	1.0858158434672336	[1785]	[1009,1036]	6	hSpCas9	negative selection	1389813
23048049	23048072	20	-	26627737	HeLa	viability after 8 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	-0.20586625041294404	[2227]	[950,828,770]	-2	hSpCas9	negative selection	1472124
23048327	23048350	20	-	26627737	HeLa	viability after 8 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	1.2510052858017042	[74]	[186,5,64]	8	hSpCas9	negative selection	1472125
23048520	23048543	20	+	26627737	HeLa	viability after 8 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	-0.25199884128566447	[640]	[333,250,145]	-2	hSpCas9	negative selection	1472126
23048834	23048857	20	+	26627737	HeLa	viability after 8 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.4229981895820859	[399]	[283,249,180]	4	hSpCas9	negative selection	1472127
23049081	23049104	20	+	26627737	HeLa	viability after 8 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	-0.15735380202680593	[1925]	[580,900,735]	-1	hSpCas9	negative selection	1472128
23048049	23048072	20	-	26627737	HeLa	viability after 12 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.021922590876811476	[2227]	[1028,512,1309]	0	hSpCas9	negative selection	1554439
23048327	23048350	20	-	26627737	HeLa	viability after 12 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	2.237497020207954	[74]	[243,54,151]	9	hSpCas9	negative selection	1554440
23048520	23048543	20	+	26627737	HeLa	viability after 12 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.0874215365998725	[640]	[347,236,265]	0	hSpCas9	negative selection	1554441
23048834	23048857	20	+	26627737	HeLa	viability after 12 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	-0.12775648221920993	[399]	[101,98,256]	-1	hSpCas9	negative selection	1554442
23049081	23049104	20	+	26627737	HeLa	viability after 12 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.07690571653473688	[1925]	[862,1011,625]	0	hSpCas9	negative selection	1554443
23048049	23048072	20	-	26627737	HeLa	viability after 15 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.14615495844153337	[2227]	[978,889,1153]	1	hSpCas9	negative selection	1636754
23048327	23048350	20	-	26627737	HeLa	viability after 15 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	1.501239125641364	[74]	[88,74,95]	8	hSpCas9	negative selection	1636755
23048520	23048543	20	+	26627737	HeLa	viability after 15 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.6112725496308651	[640]	[249,546,400]	5	hSpCas9	negative selection	1636756
23048834	23048857	20	+	26627737	HeLa	viability after 15 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	-0.6596626515135247	[399]	[109,97,100]	-5	hSpCas9	negative selection	1636757
23049081	23049104	20	+	26627737	HeLa	viability after 15 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	-0.29546223230595925	[1925]	[468,832,614]	-3	hSpCas9	negative selection	1636758
23048049	23048072	20	-	26627737	HeLa	viability after 18 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.12933411517631876	[2227]	[630,740,1153]	1	hSpCas9	negative selection	1719069
23048327	23048350	20	-	26627737	HeLa	viability after 18 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	1.504687492492175	[74]	[56,65,95]	8	hSpCas9	negative selection	1719070
23048520	23048543	20	+	26627737	HeLa	viability after 18 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.6099958465110895	[640]	[162,457,400]	5	hSpCas9	negative selection	1719071
23048834	23048857	20	+	26627737	HeLa	viability after 18 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	-0.6925833440054121	[399]	[66,83,100]	-6	hSpCas9	negative selection	1719072
23049081	23049104	20	+	26627737	HeLa	viability after 18 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	-0.28837488667306	[1925]	[326,681,614]	-2	hSpCas9	negative selection	1719073
23048049	23048072	20	-	26627737	HCT116	viability after 6 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.795260818359377	[3730]	[1227,901]	4	hSpCas9	negative selection	1801384
23048327	23048350	20	-	26627737	HCT116	viability after 6 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	-1.1562688720465357	[434]	[69,8]	-6	hSpCas9	negative selection	1801385
23048520	23048543	20	+	26627737	HCT116	viability after 6 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	-0.16639442288903417	[2179]	[432,234]	-1	hSpCas9	negative selection	1801386
23048834	23048857	20	+	26627737	HCT116	viability after 6 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.4445089239621711	[526]	[46,148]	2	hSpCas9	negative selection	1801387
23049081	23049104	20	+	26627737	HCT116	viability after 6 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.11216252994012477	[2548]	[659,307]	0	hSpCas9	negative selection	1801388
23048049	23048072	20	-	26627737	HCT116	viability after 8 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.9233791394107755	[1058]	[1201,944,1173]	8	hSpCas9	negative selection	1883699
23048327	23048350	20	-	26627737	HCT116	viability after 8 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.009975080188615149	[164]	[107,79,86]	0	hSpCas9	negative selection	1883700
23048520	23048543	20	+	26627737	HCT116	viability after 8 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	-0.1810933919289548	[814]	[490,465,234]	-2	hSpCas9	negative selection	1883701
23048834	23048857	20	+	26627737	HCT116	viability after 8 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.826105531252666	[252]	[283,199,257]	7	hSpCas9	negative selection	1883702
23049081	23049104	20	+	26627737	HCT116	viability after 8 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	-0.1379510355639071	[1350]	[750,439,837]	-1	hSpCas9	negative selection	1883703
23048049	23048072	20	-	26627737	HCT116	viability after 9 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	1.0487656497775326	[3730]	[2847,1438]	7	hSpCas9	negative selection	1966014
23048327	23048350	20	-	26627737	HCT116	viability after 9 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.2671714147986825	[434]	[55,205]	2	hSpCas9	negative selection	1966015
23048520	23048543	20	+	26627737	HCT116	viability after 9 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	-0.431288508783751	[2179]	[262,564]	-3	hSpCas9	negative selection	1966016
23048834	23048857	20	+	26627737	HCT116	viability after 9 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.9736905168037777	[526]	[396,180]	6	hSpCas9	negative selection	1966017
23049081	23049104	20	+	26627737	HCT116	viability after 9 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.4444653264071978	[2548]	[680,1119]	3	hSpCas9	negative selection	1966018
23048049	23048072	20	-	26627737	HCT116	viability after 12 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.7177362399539344	[1058]	[1076,559,1085]	6	hSpCas9	negative selection	2048329
23048327	23048350	20	-	26627737	HCT116	viability after 12 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.7177336622375452	[164]	[93,138,198]	6	hSpCas9	negative selection	2048330
23048520	23048543	20	+	26627737	HCT116	viability after 12 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.09074643835459262	[814]	[523,605,235]	1	hSpCas9	negative selection	2048331
23048834	23048857	20	+	26627737	HCT116	viability after 12 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.46991120736457065	[252]	[189,227,134]	4	hSpCas9	negative selection	2048332
23049081	23049104	20	+	26627737	HCT116	viability after 12 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	-0.08536655932772286	[1350]	[820,493,674]	-1	hSpCas9	negative selection	2048333
23048049	23048072	20	-	26627737	HCT116	viability after 15 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.82450499782043	[1058]	[1515,812,956]	7	hSpCas9	negative selection	2130644
23048327	23048350	20	-	26627737	HCT116	viability after 15 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.7218146481184876	[164]	[138,192,134]	6	hSpCas9	negative selection	2130645
23048520	23048543	20	+	26627737	HCT116	viability after 15 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.007905346001780389	[814]	[394,564,442]	0	hSpCas9	negative selection	2130646
23048834	23048857	20	+	26627737	HCT116	viability after 15 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.4837206780965967	[252]	[222,190,197]	4	hSpCas9	negative selection	2130647
23049081	23049104	20	+	26627737	HCT116	viability after 15 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	-0.19284502422514693	[1350]	[1112,361,614]	-2	hSpCas9	negative selection	2130648
23048049	23048072	20	-	26627737	HCT116	viability after 18 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	1.0059947046181312	[1058]	[788,994,1315]	7	hSpCas9	negative selection	2212959
23048327	23048350	20	-	26627737	HCT116	viability after 18 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.42398914165444146	[164]	[119,67,136]	3	hSpCas9	negative selection	2212960
23048520	23048543	20	+	26627737	HCT116	viability after 18 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.07890057915088855	[814]	[351,557,324]	0	hSpCas9	negative selection	2212961
23048834	23048857	20	+	26627737	HCT116	viability after 18 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.28894529108162004	[252]	[194,81,176]	2	hSpCas9	negative selection	2212962
23049081	23049104	20	+	26627737	HCT116	viability after 18 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.5183144406171181	[1350]	[813,1014,973]	4	hSpCas9	negative selection	2212963
23049293	23049316	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGACATCGGCAGCCACCGAGG	THBD	ENSG00000178726	-0.21425451692788253	[3,3]	[2,1]	-3	hSpCas9	positive selection	3026612
23048753	23048776	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACTGCAGCGTGGAGAACGGCGG	THBD	ENSG00000178726	0.7087716081497001	[3,3]	[7,2]	9	hSpCas9	positive selection	3026613
23048921	23048944	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGCCGTAGGTGATCGAGACGG	THBD	ENSG00000178726	0.4330735786915658	[1,1]	[0,3]	8	hSpCas9	positive selection	3026614
23049160	23049183	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTTGTCTCCCGTAACCCACTGG	THBD	ENSG00000178726	0.4486058474041056	[4,3]	[2,6]	8	hSpCas9	positive selection	3026615
23049293	23049316	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGACATCGGCAGCCACCGAGG	THBD	ENSG00000178726	0.10293080622563895	[3,3]	[3,1]	1	hSpCas9	positive selection	3094470
23048753	23048776	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACTGCAGCGTGGAGAACGGCGG	THBD	ENSG00000178726	0.19535225321720978	[3,3]	[4,1]	3	hSpCas9	positive selection	3094471
23048921	23048944	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGCCGTAGGTGATCGAGACGG	THBD	ENSG00000178726	-0.23954938512249868	[1,1]	[1,0]	-4	hSpCas9	positive selection	3094472
23049160	23049183	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTTGTCTCCCGTAACCCACTGG	THBD	ENSG00000178726	0.5048774054361236	[4,4]	[6,3]	8	hSpCas9	positive selection	3094473
23048924	23048947		-	24336571	A375	resistance to PLX after 7 days	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.05293704309825742	[7,7]	[8,5]	-1	hSpCas9	positive selection	3150123
23049268	23049291		+	24336571	A375	resistance to PLX after 7 days	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.4645971644021625	[10,10]	[6,7]	-9	hSpCas9	positive selection	3150124
23048924	23048947		-	24336571	A375	resistance to PLX after 14 days	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.30457591000516504	[5,5]	[1,1]	-3	hSpCas9	positive selection	3207916
23049268	23049291		+	24336571	A375	resistance to PLX after 14 days	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.42288854648039353	[7,11]	[2,3]	-5	hSpCas9	positive selection	3207917
23048924	23048947		-	24336571	A375	viability after 7 days	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.1160359779236031	[8]	[7,7]	-2	hSpCas9	negative selection	3265709
23049268	23049291		+	24336571	A375	viability after 7 days	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.7084966104243675	[6]	[10,10]	9	hSpCas9	negative selection	3265710
23048924	23048947		-	24336571	A375	viability after 14 days	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.40495122366938097	[8]	[5,5]	-5	hSpCas9	negative selection	3323502
23049268	23049291		+	24336571	A375	viability after 14 days	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.6353884974782905	[6]	[7,11]	7	hSpCas9	negative selection	3323503
23049197	23049220	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	2.399345216318263	[28,28]	[0,0]	8	hSpCas9	positive selection	3397048
23048567	23048590	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	0.5430806937797126	[104,104]	[0,0]	2	hSpCas9	positive selection	3397049
23049340	23049363	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	2.672363710724679	[23,23]	[0,0]	8	hSpCas9	positive selection	3397050
23049292	23049315	20	+	26780180	HT29	viability (Avana library 4 designs)	AATGACATCGGCAGCCACCGAGG	THBD	ENSG00000178726	0.730092843387413	[]	[]	3	hSpCas9	negative selection	3465351
23048753	23048776	20	-	26780180	HT29	viability (Avana library 4 designs)	GACTGCAGCGTGGAGAACGGCGG	THBD	ENSG00000178726	0.359091346113958	[]	[]	1	hSpCas9	negative selection	3465352
23048920	23048943	20	+	26780180	HT29	viability (Avana library 4 designs)	GGTGCCGTAGGTGATCGAGACGG	THBD	ENSG00000178726	1.05595026517814	[]	[]	4	hSpCas9	negative selection	3465353
23049159	23049182	20	+	26780180	HT29	viability (Avana library 4 designs)	TGTTGTCTCCCGTAACCCACTGG	THBD	ENSG00000178726	1.2417419795585	[]	[]	5	hSpCas9	negative selection	3465354
23049159	23049182	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTTGTCTCCCGTAACCCACTGG	THBD	ENSG00000178726	0.818332968867626	[]	[]	1	hSpCas9	negative selection	3568503
23049292	23049315	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATGACATCGGCAGCCACCGAGG	THBD	ENSG00000178726	4.90730956765684	[]	[]	8	hSpCas9	negative selection	3568504
23048753	23048776	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACTGCAGCGTGGAGAACGGCGG	THBD	ENSG00000178726	1.62621315914076	[]	[]	2	hSpCas9	negative selection	3568505
23048920	23048943	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGCCGTAGGTGATCGAGACGG	THBD	ENSG00000178726	2.42196398563541	[]	[]	3	hSpCas9	negative selection	3568506
23049344	23049367	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	-0.145123493724229	[]	[]	0	hSpCas9	negative selection	3568507
23049174	23049197	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCCTGCGCGGCTTCCAGTGGG	THBD	ENSG00000178726	4.45028542228218	[]	[]	7	hSpCas9	negative selection	3568508
23049159	23049182	20	+	26780180	A375	viability (Avana lentiGuide)	TGTTGTCTCCCGTAACCCACTGG	THBD	ENSG00000178726	0.998466948052521	[]	[]	1	hSpCas9	negative selection	3677162
23049292	23049315	20	+	26780180	A375	viability (Avana lentiGuide)	AATGACATCGGCAGCCACCGAGG	THBD	ENSG00000178726	-3.67913553855861	[]	[]	-6	hSpCas9	negative selection	3677163
23048753	23048776	20	-	26780180	A375	viability (Avana lentiGuide)	GACTGCAGCGTGGAGAACGGCGG	THBD	ENSG00000178726	-0.630105226273672	[]	[]	-1	hSpCas9	negative selection	3677164
23048920	23048943	20	+	26780180	A375	viability (Avana lentiGuide)	GGTGCCGTAGGTGATCGAGACGG	THBD	ENSG00000178726	12.444474183975	[]	[]	7	hSpCas9	negative selection	3677165
23049344	23049367	20	-	26780180	A375	viability (Avana lentiGuide)	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	3.75850811372648	[]	[]	3	hSpCas9	negative selection	3677166
23049174	23049197	20	-	26780180	A375	viability (Avana lentiGuide)	GCCCCTGCGCGGCTTCCAGTGGG	THBD	ENSG00000178726	1.77203690482535	[]	[]	2	hSpCas9	negative selection	3677167
23049159	23049182	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTTGTCTCCCGTAACCCACTGG	THBD	ENSG00000178726	0.011127040132141344	[4]	[4,4]	0	hSpCas9	positive selection	3785769
23049292	23049315	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGACATCGGCAGCCACCGAGG	THBD	ENSG00000178726	0.24794945308835487	[4]	[6,4]	7	hSpCas9	positive selection	3785770
23048753	23048776	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACTGCAGCGTGGAGAACGGCGG	THBD	ENSG00000178726	-0.24184568446058086	[3]	[3,2]	-4	hSpCas9	positive selection	3785771
23048920	23048943	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGCCGTAGGTGATCGAGACGG	THBD	ENSG00000178726	-0.15339290769122893	[4]	[4,2]	-2	hSpCas9	positive selection	3785772
23049344	23049367	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	-0.1296556468570198	[4]	[4,3]	-2	hSpCas9	positive selection	3785773
23049174	23049197	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCCTGCGCGGCTTCCAGTGGG	THBD	ENSG00000178726	0.34032497421330693	[4]	[6,5]	8	hSpCas9	positive selection	3785774
23049159	23049182	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTTGTCTCCCGTAACCCACTGG	THBD	ENSG00000178726	0.12235934545568286	[5]	[4,5]	2	hSpCas9	positive selection	3894376
23049292	23049315	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGACATCGGCAGCCACCGAGG	THBD	ENSG00000178726	-0.41316535096481116	[4]	[3,1]	-5	hSpCas9	positive selection	3894377
23048753	23048776	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACTGCAGCGTGGAGAACGGCGG	THBD	ENSG00000178726	-0.6209432451613794	[4]	[0,3]	-7	hSpCas9	positive selection	3894378
23048920	23048943	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGCCGTAGGTGATCGAGACGG	THBD	ENSG00000178726	-0.34715701021291295	[3]	[1,3]	-4	hSpCas9	positive selection	3894379
23049344	23049367	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.16080913608284483	[4]	[4,4]	4	hSpCas9	positive selection	3894380
23049174	23049197	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCCTGCGCGGCTTCCAGTGGG	THBD	ENSG00000178726	0.25913353203570716	[5]	[5,5]	7	hSpCas9	positive selection	3894381
23049399	23049422	20	+	26780180	A375	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	1.25632867985275	[]	[]	6	hSpCas9	negative selection	4003727
23049340	23049363	20	+	26780180	A375	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.759483189853857	[]	[]	3	hSpCas9	negative selection	4003728
23048924	23048947	20	-	26780180	A375	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.814741532864589	[]	[]	3	hSpCas9	negative selection	4003729
23049268	23049291	20	+	26780180	A375	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.296294554055565	[]	[]	0	hSpCas9	negative selection	4003730
23048567	23048590	20	-	26780180	A375	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	1.21603180371223	[]	[]	6	hSpCas9	negative selection	4003731
23049197	23049220	20	-	26780180	A375	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.558134802329613	[]	[]	1	hSpCas9	negative selection	4003732
23049399	23049422	20	+	26780180	HT29	viability (GeCKOv2 library)	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	1.81117189314293	[]	[]	8	hSpCas9	negative selection	4111693
23049340	23049363	20	+	26780180	HT29	viability (GeCKOv2 library)	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.517078461503598	[]	[]	1	hSpCas9	negative selection	4111694
23048924	23048947	20	-	26780180	HT29	viability (GeCKOv2 library)	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.465432656156014	[]	[]	-8	hSpCas9	negative selection	4111695
23049268	23049291	20	+	26780180	HT29	viability (GeCKOv2 library)	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.098222458543527	[]	[]	-3	hSpCas9	negative selection	4111696
23048567	23048590	20	-	26780180	HT29	viability (GeCKOv2 library)	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	1.68115562412635	[]	[]	8	hSpCas9	negative selection	4111697
23049197	23049220	20	-	26780180	HT29	viability (GeCKOv2 library)	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.629758329657532	[]	[]	2	hSpCas9	negative selection	4111698
23048924	23048947	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.1525829168870999	[2]	[2,0]	-4	hSpCas9	positive selection	4176502
23049268	23049291	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.016008774164776557	[3]	[2,1]	0	hSpCas9	positive selection	4176503
23048924	23048947	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.4050081861870982	[2]	[3,4,0,0]	3	hSpCas9	positive selection	4240524
23049268	23049291	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.7871882679746329	[2]	[1,2,6,0]	5	hSpCas9	positive selection	4240525
23048924	23048947	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.07256804646991169	[3]	[3,1]	-1	hSpCas9	positive selection	4302940
23049268	23049291	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.08364814169560053	[2]	[3,0]	-2	hSpCas9	positive selection	4302941
23049399	23049422	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.5873651365069738	[2]	[2,3]	9	hSpCas9	positive selection	4302942
23049197	23049220	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.2824885699598534	[1]	[2,0]	5	hSpCas9	positive selection	4367194
23048567	23048590	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.370829189627667	[2]	[1,0]	-7	hSpCas9	positive selection	4367195
23049340	23049363	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.24944738601570404	[1]	[1,0]	-5	hSpCas9	positive selection	4367196
23048723	23048745	20	-	27760321	OCIAML3	viability	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	0.2819432437167904	[687,521]	[515,641]	3	hSpCas9	negative selection	4446737
23048924	23048946	20	-	27760321	OCIAML3	viability	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.27754037651140295	[592,476]	[255,456]	-3	hSpCas9	negative selection	4446738
23049092	23049114	20	+	27760321	OCIAML3	viability	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	0.20005658566125512	[639,475]	[525,458]	2	hSpCas9	negative selection	4446739
23049117	23049139	20	-	27760321	OCIAML3	viability	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	-0.07213155181474046	[700,545]	[342,613]	-1	hSpCas9	negative selection	4446740
23049269	23049291	20	+	27760321	OCIAML3	viability	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.3267258932348873	[783,820]	[489,519]	-3	hSpCas9	negative selection	4446741
23048723	23048745	20	-	27760321	OCIAML2	viability	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	-0.7017241473921859	[687,521]	[285,314]	-6	hSpCas9	negative selection	4530200
23048924	23048946	20	-	27760321	OCIAML2	viability	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.19954817629909372	[592,476]	[303,467]	-3	hSpCas9	negative selection	4530201
23049092	23049114	20	+	27760321	OCIAML2	viability	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	-0.3778370362994534	[639,475]	[314,382]	-4	hSpCas9	negative selection	4530202
23049117	23049139	20	-	27760321	OCIAML2	viability	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	0.35245925437796444	[700,545]	[522,792]	5	hSpCas9	negative selection	4530203
23049269	23049291	20	+	27760321	OCIAML2	viability	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.3303262623217448	[783,820]	[537,493]	-4	hSpCas9	negative selection	4530204
23048723	23048745	20	-	27760321	MV411	viability	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	0.3878556975539113	[687,521]	[538,486]	2	hSpCas9	negative selection	4613663
23048924	23048946	20	-	27760321	MV411	viability	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	1.21910602643105	[592,476]	[921,659]	8	hSpCas9	negative selection	4613664
23049092	23049114	20	+	27760321	MV411	viability	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	0.2397004295477842	[639,475]	[386,496]	1	hSpCas9	negative selection	4613665
23049117	23049139	20	-	27760321	MV411	viability	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	1.249873419075241	[700,545]	[896,1083]	8	hSpCas9	negative selection	4613666
23049269	23049291	20	+	27760321	MV411	viability	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.20530070930377964	[783,820]	[753,402]	1	hSpCas9	negative selection	4613667
23048723	23048745	20	-	27760321	HL60	viability	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	-0.21614255394110907	[687,521]	[456,384]	-2	hSpCas9	negative selection	4697126
23048924	23048946	20	-	27760321	HL60	viability	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.6593631858364277	[592,476]	[213,339]	-6	hSpCas9	negative selection	4697127
23049092	23049114	20	+	27760321	HL60	viability	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	0.013351302191360659	[639,475]	[439,472]	0	hSpCas9	negative selection	4697128
23049117	23049139	20	-	27760321	HL60	viability	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	0.050484232042513066	[700,545]	[500,547]	0	hSpCas9	negative selection	4697129
23049269	23049291	20	+	27760321	HL60	viability	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.32428720398119326	[783,820]	[452,603]	-4	hSpCas9	negative selection	4697130
23048723	23048745	20	-	27760321	HT1080	viability	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	0.8168376501682246	[521,407]	[185,479]	4	hSpCas9	negative selection	4780589
23048924	23048946	20	-	27760321	HT1080	viability	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	2.240579668194671	[476,371]	[464,1164]	9	hSpCas9	negative selection	4780590
23049092	23049114	20	+	27760321	HT1080	viability	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	0.7608777984639618	[475,371]	[185,395]	4	hSpCas9	negative selection	4780591
23049117	23049139	20	-	27760321	HT1080	viability	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	0.786224934341483	[545,425]	[362,301]	4	hSpCas9	negative selection	4780592
23049269	23049291	20	+	27760321	HT1080	viability	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.22679927135172506	[820,640]	[367,310]	1	hSpCas9	negative selection	4780593
23048723	23048745	20	-	27760321	HT29	viability after 7 days	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	0.25959040791191884	[521,407]	[738,706,703]	4	hSpCas9	negative selection	4864052
23048924	23048946	20	-	27760321	HT29	viability after 7 days	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.04002664426206781	[476,371]	[592,394,609]	0	hSpCas9	negative selection	4864053
23049092	23049114	20	+	27760321	HT29	viability after 7 days	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	0.6827448942985882	[475,371]	[922,770,934]	9	hSpCas9	negative selection	4864054
23049117	23049139	20	-	27760321	HT29	viability after 7 days	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	0.6343455505980923	[545,425]	[1195,820,924]	8	hSpCas9	negative selection	4864055
23049269	23049291	20	+	27760321	HT29	viability after 7 days	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.20860028127126806	[820,640]	[747,977,706]	-3	hSpCas9	negative selection	4864056
23048723	23048745	20	-	27760321	HT29	viability after 25 days	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	0.6794616441501478	[521,407]	[621,891,1075]	7	hSpCas9	negative selection	4947515
23048924	23048946	20	-	27760321	HT29	viability after 25 days	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.3295193644356066	[476,371]	[568,723,528]	3	hSpCas9	negative selection	4947516
23049092	23049114	20	+	27760321	HT29	viability after 25 days	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	0.9905664169566072	[475,371]	[1163,639,1082]	9	hSpCas9	negative selection	4947517
23049117	23049139	20	-	27760321	HT29	viability after 25 days	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	0.8327936961082975	[545,425]	[1053,902,1006]	8	hSpCas9	negative selection	4947518
23049269	23049291	20	+	27760321	HT29	viability after 25 days	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.5371972551749693	[820,640]	[1169,934,1569]	6	hSpCas9	negative selection	4947519
23048723	23048745	20	-	27760321	HT29	viability after 22 days	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	0.5425943182597073	[521,407]	[701,907,740]	6	hSpCas9	negative selection	5030978
23048924	23048946	20	-	27760321	HT29	viability after 22 days	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.6102046321732512	[476,371]	[793,699,751]	6	hSpCas9	negative selection	5030979
23049092	23049114	20	+	27760321	HT29	viability after 22 days	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	0.9687594522013815	[475,371]	[1289,750,826]	9	hSpCas9	negative selection	5030980
23049117	23049139	20	-	27760321	HT29	viability after 22 days	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	0.5241548810130824	[545,425]	[832,695,894]	6	hSpCas9	negative selection	5030981
23049269	23049291	20	+	27760321	HT29	viability after 22 days	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.31888917165421726	[820,640]	[988,926,1249]	3	hSpCas9	negative selection	5030982
23048723	23048745	20	-	27760321	HT29	viability after 19 days	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	0.8612121287422756	[521,407]	[891,1539,476]	8	hSpCas9	negative selection	5114441
23048924	23048946	20	-	27760321	HT29	viability after 19 days	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.5941803613289535	[476,371]	[376,625,1141]	6	hSpCas9	negative selection	5114442
23049092	23049114	20	+	27760321	HT29	viability after 19 days	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	1.054305106483225	[475,371]	[1280,858,912]	9	hSpCas9	negative selection	5114443
23049117	23049139	20	-	27760321	HT29	viability after 19 days	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	1.109418629709705	[545,425]	[1251,1301,1053]	9	hSpCas9	negative selection	5114444
23049269	23049291	20	+	27760321	HT29	viability after 19 days	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.13652625389309703	[820,640]	[1007,670,632]	-1	hSpCas9	negative selection	5114445
23048723	23048745	20	-	27760321	HT29	viability after 16 days	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	0.3741521369367156	[521,407]	[584,538,893]	4	hSpCas9	negative selection	5197904
23048924	23048946	20	-	27760321	HT29	viability after 16 days	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.11268212503887118	[476,371]	[599,534,412]	1	hSpCas9	negative selection	5197905
23049092	23049114	20	+	27760321	HT29	viability after 16 days	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	0.7507112831245086	[475,371]	[787,938,662]	8	hSpCas9	negative selection	5197906
23049117	23049139	20	-	27760321	HT29	viability after 16 days	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	0.45084675855049583	[545,425]	[956,614,680]	5	hSpCas9	negative selection	5197907
23049269	23049291	20	+	27760321	HT29	viability after 16 days	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.0437121133750733	[820,640]	[748,691,1082]	0	hSpCas9	negative selection	5197908
23048723	23048745	20	-	27760321	HT29	viability after 13 days	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	0.5315916883072838	[521,407]	[729,1041,579]	6	hSpCas9	negative selection	5281367
23048924	23048946	20	-	27760321	HT29	viability after 13 days	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.22617279850334263	[476,371]	[766,460,503]	3	hSpCas9	negative selection	5281368
23049092	23049114	20	+	27760321	HT29	viability after 13 days	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	0.8592345453379765	[475,371]	[860,751,1053]	9	hSpCas9	negative selection	5281369
23049117	23049139	20	-	27760321	HT29	viability after 13 days	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	0.6160138841777419	[545,425]	[877,745,961]	7	hSpCas9	negative selection	5281370
23049269	23049291	20	+	27760321	HT29	viability after 13 days	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.007030199839789031	[820,640]	[688,1154,720]	0	hSpCas9	negative selection	5281371
23048723	23048745	20	-	27760321	HT29	viability after 10 days	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	0.0696912233675458	[521,407]	[558,691,579]	0	hSpCas9	negative selection	5364830
23048924	23048946	20	-	27760321	HT29	viability after 10 days	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.06277704740551251	[476,371]	[595,562,502]	0	hSpCas9	negative selection	5364831
23049092	23049114	20	+	27760321	HT29	viability after 10 days	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	1.2339701291065714	[475,371]	[1588,1077,1067]	9	hSpCas9	negative selection	5364832
23049117	23049139	20	-	27760321	HT29	viability after 10 days	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	0.4761029387596559	[545,425]	[993,757,778]	6	hSpCas9	negative selection	5364833
23049269	23049291	20	+	27760321	HT29	viability after 10 days	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.20778059441784613	[820,640]	[974,792,606]	-3	hSpCas9	negative selection	5364834
23048723	23048745	20	-	27760321	MOLM13	viability	ACGCGTGCAATGCGATCCCTGG	THBD	ENSG00000178726	-0.8346975467893422	[687,521]	[184,193]	-5	hSpCas9	negative selection	5448293
23048924	23048946	20	-	27760321	MOLM13	viability	CCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-1.1631441306664927	[592,476]	[173,99]	-6	hSpCas9	negative selection	5448294
23049092	23049114	20	+	27760321	MOLM13	viability	ACGCACAACGGGCCGCAGAGGG	THBD	ENSG00000178726	1.4831772878190104	[639,475]	[207,1437]	8	hSpCas9	negative selection	5448295
23049117	23049139	20	-	27760321	MOLM13	viability	GCACGGCTCGACCTCAATGGGG	THBD	ENSG00000178726	0.3407653411361441	[700,545]	[187,658]	2	hSpCas9	negative selection	5448296
23049269	23049291	20	+	27760321	MOLM13	viability	CCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	-0.47655197962954854	[783,820]	[446,224]	-3	hSpCas9	negative selection	5448297
23048128	23048151	20	+	27661255	K562	viability	GGGGAGGTTGTGGCACACCCCGG	THBD	ENSG00000178726	0.17978281761731835	[939,986]	[978,778]	6	dCas9-KRAB	negative selection	5517117
23048390	23048413	20	+	27661255	K562	viability	GCTCTGAAGCACGGGTCCACGGG	THBD	ENSG00000178726	-0.2790992939348964	[82,44]	[54,31]	-6	dCas9-KRAB	negative selection	5517118
23048530	23048553	20	+	27661255	K562	viability	GTCCTCGCACCGGTGTTGGTCGG	THBD	ENSG00000178726	-0.02098722710821549	[545,574]	[496,392]	-1	dCas9-KRAB	negative selection	5517119
23048569	23048592	20	+	27661255	K562	viability	GGTCTCGCACATGCACGAGTAGG	THBD	ENSG00000178726	0.13690281422276457	[755,878]	[802,641]	5	dCas9-KRAB	negative selection	5517120
23049228	23049251	20	+	27661255	K562	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.19074975370000852	[683,790]	[722,625]	6	dCas9-KRAB	negative selection	5517121
23048539	23048562	20	-	27661255	K562	viability	GGCTGGCGGCCGACCAACACCGG	THBD	ENSG00000178726	0.2973476337296963	[245,355]	[326,264]	8	dCas9-KRAB	negative selection	5517122
23048556	23048579	20	-	27661255	K562	viability	GTGCGAGACCGGCTACCGGCTGG	THBD	ENSG00000178726	0.101380867244665	[961,1012]	[852,838]	3	dCas9-KRAB	negative selection	5517123
23048560	23048583	20	-	27661255	K562	viability	GCATGTGCGAGACCGGCTACCGG	THBD	ENSG00000178726	-0.016494991669650627	[1775,1878]	[1512,1380]	0	dCas9-KRAB	negative selection	5517124
23049174	23049197	20	-	27661255	K562	viability	GCCCCTGCGCGGCTTCCAGTGGG	THBD	ENSG00000178726	-0.18276409651385958	[864,934]	[652,614]	-5	dCas9-KRAB	negative selection	5517125
23049607	23049630	20	-	27661255	K562	viability	GTGTCTGGGCTGGGACGGACAGG	THBD	ENSG00000178726	0.20940731250619649	[1099,1332]	[1218,1034]	7	dCas9-KRAB	negative selection	5517126
23048924	23048947	20	-	27260156	BXPC3	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.5709510197127166	[603]	[941,953,908,938]	9	hSpCas9	negative selection	5575400
23049268	23049291	20	+	27260156	BXPC3	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.6149491359706897	[207]	[345,303,342,337]	9	hSpCas9	negative selection	5575401
23049399	23049422	20	+	27260156	BXPC3	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.059366641471588544	[295]	[295,209,347,343]	-1	hSpCas9	negative selection	5575402
23049197	23049220	20	-	27260156	BXPC3	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.12700993244139003	[86]	[126,96,54,115]	3	hSpCas9	negative selection	5639654
23048567	23048590	20	-	27260156	BXPC3	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.32130037461574135	[281]	[228,260,207,243]	-6	hSpCas9	negative selection	5639655
23049340	23049363	20	+	27260156	BXPC3	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.03945947455728849	[89]	[42,121,116,86]	-1	hSpCas9	negative selection	5639656
23048924	23048947	20	-	27260156	A673	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.4334873407077156	[603]	[1007,844,980,1094]	8	hSpCas9	negative selection	5696651
23049268	23049291	20	+	27260156	A673	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.4657685507923113	[207]	[420,363,258,343]	9	hSpCas9	negative selection	5696652
23049399	23049422	20	+	27260156	A673	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.21491686876567961	[295]	[395,261,258,319]	-5	hSpCas9	negative selection	5696653
23049197	23049220	20	-	27260156	A673	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.09092475067527772	[86]	[149,68,109,121]	2	hSpCas9	negative selection	5760905
23048567	23048590	20	-	27260156	A673	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.05720299410758378	[281]	[418,294,290,306]	-1	hSpCas9	negative selection	5760906
23049340	23049363	20	+	27260156	A673	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.14141611640629392	[89]	[96,78,101,114]	-4	hSpCas9	negative selection	5760907
23048924	23048947	20	-	27260156	A375	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.30079624620473583	[603]	[1003,945,883,673]	4	hSpCas9	negative selection	5817902
23049268	23049291	20	+	27260156	A375	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.7698798833693884	[207]	[494,519,299,361]	9	hSpCas9	negative selection	5817903
23049399	23049422	20	+	27260156	A375	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.1840667703185539	[295]	[306,334,316,265]	-3	hSpCas9	negative selection	5817904
23049197	23049220	20	-	27260156	A375	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	-0.02481933744404463	[86]	[58,149,70,122]	0	hSpCas9	negative selection	5882156
23048567	23048590	20	-	27260156	A375	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.33025600954620493	[281]	[353,237,224,230]	-5	hSpCas9	negative selection	5882157
23049340	23049363	20	+	27260156	A375	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.026169844128421715	[89]	[108,111,49,151]	0	hSpCas9	negative selection	5882158
23048924	23048947	20	-	27260156	COLO741	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.6606621372543688	[603]	[1542,1075,1075]	9	hSpCas9	negative selection	5939153
23049268	23049291	20	+	27260156	COLO741	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.4283011255746494	[207]	[462,304,315]	8	hSpCas9	negative selection	5939154
23049399	23049422	20	+	27260156	COLO741	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.20680018408925477	[295]	[495,402,415]	4	hSpCas9	negative selection	5939155
23049197	23049220	20	-	27260156	COLO741	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.7122921762697532	[86]	[186,185,173]	9	hSpCas9	negative selection	6003407
23048567	23048590	20	-	27260156	COLO741	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	0.0105877487806737	[281]	[320,405,357]	0	hSpCas9	negative selection	6003408
23049340	23049363	20	+	27260156	COLO741	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.36993429177936665	[89]	[174,72,195]	7	hSpCas9	negative selection	6003409
23048924	23048947	20	-	27260156	CAL120	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.5691518872154162	[603]	[844,1216,1239]	8	hSpCas9	negative selection	6060404
23049268	23049291	20	+	27260156	CAL120	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.38381917779352326	[207]	[502,258,276]	6	hSpCas9	negative selection	6060405
23049399	23049422	20	+	27260156	CAL120	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.6268962378505077	[295]	[385,965,330]	8	hSpCas9	negative selection	6060406
23049197	23049220	20	-	27260156	CAL120	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.0402708067962676	[86]	[103,126,101]	0	hSpCas9	negative selection	6124658
23048567	23048590	20	-	27260156	CAL120	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	0.027578578656523578	[281]	[212,471,365]	0	hSpCas9	negative selection	6124659
23049340	23049363	20	+	27260156	CAL120	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.2896480167965283	[89]	[66,77,252]	4	hSpCas9	negative selection	6124660
23048924	23048947	20	-	27260156	CADOES1	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.25589905771445426	[603]	[695,558,802,622]	4	hSpCas9	negative selection	6181655
23049268	23049291	20	+	27260156	CADOES1	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.6232963006372143	[207]	[324,238,221,409]	8	hSpCas9	negative selection	6181656
23049399	23049422	20	+	27260156	CADOES1	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.24701541278646316	[295]	[376,227,208,498]	4	hSpCas9	negative selection	6181657
23049197	23049220	20	-	27260156	CADOES1	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.2825143184291439	[86]	[75,118,119,77]	5	hSpCas9	negative selection	6245909
23048567	23048590	20	-	27260156	CADOES1	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	0.4915660497334576	[281]	[324,477,210,464]	7	hSpCas9	negative selection	6245910
23049340	23049363	20	+	27260156	CADOES1	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.9425775281257271	[89]	[46,39,73,11]	-9	hSpCas9	negative selection	6245911
23048924	23048947	20	-	27260156	EWS502	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.6409117734843144	[603]	[839,922,882,1388]	9	hSpCas9	negative selection	6302906
23049268	23049291	20	+	27260156	EWS502	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.42923165507850114	[207]	[265,283,332,307]	7	hSpCas9	negative selection	6302907
23049399	23049422	20	+	27260156	EWS502	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.6084252489469979	[295]	[529,427,512,431]	9	hSpCas9	negative selection	6302908
23049197	23049220	20	-	27260156	EWS502	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.6097100953449228	[86]	[348,76,31,74]	9	hSpCas9	negative selection	6367160
23048567	23048590	20	-	27260156	EWS502	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.1598811370688875	[281]	[136,292,207,457]	-3	hSpCas9	negative selection	6367161
23049340	23049363	20	+	27260156	EWS502	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.030177670536976287	[89]	[71,98,161,56]	0	hSpCas9	negative selection	6367162
23048924	23048947	20	-	27260156	EW8	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.4112773461153059	[603]	[738,626,564,694]	7	hSpCas9	negative selection	6424157
23049268	23049291	20	+	27260156	EW8	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.3975830771943195	[207]	[236,231,199,223]	7	hSpCas9	negative selection	6424158
23049399	23049422	20	+	27260156	EW8	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.1132488683487698	[295]	[296,244,242,258]	2	hSpCas9	negative selection	6424159
23049197	23049220	20	-	27260156	EW8	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.3889742327345247	[86]	[132,90,89,59]	7	hSpCas9	negative selection	6488411
23048567	23048590	20	-	27260156	EW8	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.22527311040630393	[281]	[192,252,156,184]	-4	hSpCas9	negative selection	6488412
23049340	23049363	20	+	27260156	EW8	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.09029388602296917	[89]	[37,77,112,70]	1	hSpCas9	negative selection	6488413
23048924	23048947	20	-	27260156	CORL105	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.4645708394857733	[603]	[1122,799,1019,974]	8	hSpCas9	negative selection	6545408
23049268	23049291	20	+	27260156	CORL105	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.50931187828924	[207]	[311,435,311,317]	8	hSpCas9	negative selection	6545409
23049399	23049422	20	+	27260156	CORL105	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.15387402560009156	[295]	[437,530,255,295]	3	hSpCas9	negative selection	6545410
23049197	23049220	20	-	27260156	CORL105	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.2869313975240084	[86]	[116,92,222,79]	5	hSpCas9	negative selection	6609662
23048567	23048590	20	-	27260156	CORL105	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.06137195274776219	[281]	[174,336,455,313]	-1	hSpCas9	negative selection	6609663
23049340	23049363	20	+	27260156	CORL105	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.46260751415165347	[89]	[77,80,83,63]	-7	hSpCas9	negative selection	6609664
23048924	23048947	20	-	27260156	HS294T	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.26767862084893995	[603]	[176,327,246,399]	3	hSpCas9	negative selection	6666659
23049268	23049291	20	+	27260156	HS294T	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.20149397480743647	[207]	[108,84,87,84]	2	hSpCas9	negative selection	6666660
23049399	23049422	20	+	27260156	HS294T	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.17062225660007813	[295]	[117,111,124,167]	2	hSpCas9	negative selection	6666661
23049197	23049220	20	-	27260156	HS294T	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.44198739536111153	[86]	[32,57,33,60]	6	hSpCas9	negative selection	6730913
23048567	23048590	20	-	27260156	HS294T	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.0211290471122344	[281]	[116,119,108,76]	0	hSpCas9	negative selection	6730914
23049340	23049363	20	+	27260156	HS294T	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.4670892726123679	[89]	[9,26,29,36]	-6	hSpCas9	negative selection	6730915
23048924	23048947	20	-	27260156	HCC44	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.5228381227008569	[603]	[985,879,1109,978]	8	hSpCas9	negative selection	6787910
23049268	23049291	20	+	27260156	HCC44	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.7497764729048412	[207]	[313,321,294,625]	9	hSpCas9	negative selection	6787911
23049399	23049422	20	+	27260156	HCC44	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.39614159934107906	[295]	[506,134,245,168]	-6	hSpCas9	negative selection	6787912
23049197	23049220	20	-	27260156	HCC44	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	-0.2217391537142115	[86]	[85,41,141,82]	-4	hSpCas9	negative selection	6852164
23048567	23048590	20	-	27260156	HCC44	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	0.07625055781818368	[281]	[491,152,418,332]	1	hSpCas9	negative selection	6852165
23049340	23049363	20	+	27260156	HCC44	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.12856552396516507	[89]	[112,36,144,163]	2	hSpCas9	negative selection	6852166
23048924	23048947	20	-	27260156	G402	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.20448821348015528	[603]	[695,1315,714,679]	2	hSpCas9	negative selection	6909161
23049268	23049291	20	+	27260156	G402	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.9670437322527361	[207]	[442,345,760,419]	9	hSpCas9	negative selection	6909162
23049399	23049422	20	+	27260156	G402	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.2469936511185319	[295]	[374,253,406,192]	-3	hSpCas9	negative selection	6909163
23049197	23049220	20	-	27260156	G402	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	1.1722034726863948	[86]	[562,193,191,59]	9	hSpCas9	negative selection	6973415
23048567	23048590	20	-	27260156	G402	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.0584477073109273	[281]	[415,249,349,312]	0	hSpCas9	negative selection	6973416
23049340	23049363	20	+	27260156	G402	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.1046915960782937	[89]	[9,309,83,65]	1	hSpCas9	negative selection	6973417
23048924	23048947	20	-	27260156	L33	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.578316143689418	[603]	[813,387,580,923]	9	hSpCas9	negative selection	7030412
23049268	23049291	20	+	27260156	L33	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.15220440685564185	[207]	[218,92,188,178]	3	hSpCas9	negative selection	7030413
23049399	23049422	20	+	27260156	L33	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.025831558067048954	[295]	[299,88,215,301]	0	hSpCas9	negative selection	7030414
23049197	23049220	20	-	27260156	L33	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.24413407676161603	[86]	[192,32,44,64]	5	hSpCas9	negative selection	7094666
23048567	23048590	20	-	27260156	L33	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	0.11314160340483215	[281]	[251,98,302,246]	2	hSpCas9	negative selection	7094667
23049340	23049363	20	+	27260156	L33	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.27453049958016695	[89]	[108,37,35,37]	-6	hSpCas9	negative selection	7094668
23048924	23048947	20	-	27260156	K562	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.5201143403518222	[603]	[642,717,386,1252]	6	hSpCas9	negative selection	7151663
23049268	23049291	20	+	27260156	K562	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.9717030530076349	[207]	[503,158,559,238]	9	hSpCas9	negative selection	7151664
23049399	23049422	20	+	27260156	K562	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.19156816684299632	[295]	[390,281,343,199]	2	hSpCas9	negative selection	7151665
23049197	23049220	20	-	27260156	K562	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.46402948445454406	[86]	[44,243,15,120]	6	hSpCas9	negative selection	7215917
23048567	23048590	20	-	27260156	K562	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.5017685750239714	[281]	[93,294,114,198]	-6	hSpCas9	negative selection	7215918
23049340	23049363	20	+	27260156	K562	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.11923888167219987	[89]	[136,46,33,125]	1	hSpCas9	negative selection	7215919
23048924	23048947	20	-	27260156	HT29	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.644088181921084	[603]	[1019,1144,1327,1085]	9	hSpCas9	negative selection	7272914
23049268	23049291	20	+	27260156	HT29	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.5274512887475974	[207]	[468,323,304,361]	8	hSpCas9	negative selection	7272915
23049399	23049422	20	+	27260156	HT29	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.100310504902962	[295]	[426,415,416,296]	2	hSpCas9	negative selection	7272916
23049197	23049220	20	-	27260156	HT29	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.030239914347604646	[86]	[103,121,159,52]	0	hSpCas9	negative selection	7337168
23048567	23048590	20	-	27260156	HT29	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.5165812685599277	[281]	[208,365,264,137]	-7	hSpCas9	negative selection	7337169
23049340	23049363	20	+	27260156	HT29	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.2314905508516758	[89]	[77,106,137,53]	-4	hSpCas9	negative selection	7337170
23048924	23048947	20	-	27260156	MHHES1	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.6621446404805404	[603]	[1409,1027,929,971]	9	hSpCas9	negative selection	7394165
23049268	23049291	20	+	27260156	MHHES1	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.597034798246259	[207]	[326,475,378,258]	9	hSpCas9	negative selection	7394166
23049399	23049422	20	+	27260156	MHHES1	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.0341434881763093	[295]	[424,476,237,259]	0	hSpCas9	negative selection	7394167
23049197	23049220	20	-	27260156	MHHES1	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.19950764151390388	[86]	[195,103,72,88]	3	hSpCas9	negative selection	7458419
23048567	23048590	20	-	27260156	MHHES1	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.32853528494559614	[281]	[266,331,208,215]	-6	hSpCas9	negative selection	7458420
23049340	23049363	20	+	27260156	MHHES1	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.3565159896495298	[89]	[114,59,26,107]	-6	hSpCas9	negative selection	7458421
23048924	23048947	20	-	27260156	MEWO	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.7584485033754302	[603]	[1092,776,1024]	9	hSpCas9	negative selection	7515416
23049268	23049291	20	+	27260156	MEWO	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.42687727210602633	[207]	[324,266,204]	8	hSpCas9	negative selection	7515417
23049399	23049422	20	+	27260156	MEWO	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.14737784274258448	[295]	[232,197,315]	-3	hSpCas9	negative selection	7515418
23049197	23049220	20	-	27260156	MEWO	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.25173057694071055	[86]	[138,68,90]	5	hSpCas9	negative selection	7579670
23048567	23048590	20	-	27260156	MEWO	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.38402995690758124	[281]	[285,141,194]	-7	hSpCas9	negative selection	7579671
23049340	23049363	20	+	27260156	MEWO	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.5274777916627313	[89]	[131,148,84]	9	hSpCas9	negative selection	7579672
23048924	23048947	20	-	27260156	LNCAPCLONEFGC	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.5506774308537519	[603]	[837,667,940,786]	8	hSpCas9	negative selection	7636667
23049268	23049291	20	+	27260156	LNCAPCLONEFGC	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.6511091902579317	[207]	[417,178,398,207]	8	hSpCas9	negative selection	7636668
23049399	23049422	20	+	27260156	LNCAPCLONEFGC	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.14741964741806735	[295]	[220,202,314,242]	-2	hSpCas9	negative selection	7636669
23049197	23049220	20	-	27260156	LNCAPCLONEFGC	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.4412190327616581	[86]	[94,122,85,119]	7	hSpCas9	negative selection	7700921
23048567	23048590	20	-	27260156	LNCAPCLONEFGC	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.05801368612430102	[281]	[216,224,310,239]	-1	hSpCas9	negative selection	7700922
23049340	23049363	20	+	27260156	LNCAPCLONEFGC	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.1422157439252243	[89]	[53,95,142,74]	2	hSpCas9	negative selection	7700923
23048924	23048947	20	-	27260156	PANC0327	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.2765997386753229	[603]	[829,576,754,461]	4	hSpCas9	negative selection	7757918
23049268	23049291	20	+	27260156	PANC0327	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.8412278874019521	[207]	[347,440,207,313]	9	hSpCas9	negative selection	7757919
23049399	23049422	20	+	27260156	PANC0327	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.059042808190882035	[295]	[235,158,193,430]	-1	hSpCas9	negative selection	7757920
23049197	23049220	20	-	27260156	PANC0327	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	1.1141729582767976	[86]	[104,160,255,142]	9	hSpCas9	negative selection	7822172
23048567	23048590	20	-	27260156	PANC0327	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	0.5621248552431446	[281]	[425,283,387,396]	7	hSpCas9	negative selection	7822173
23049340	23049363	20	+	27260156	PANC0327	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	1.1490912664459259	[89]	[212,201,202,90]	9	hSpCas9	negative selection	7822174
23048924	23048947	20	-	27260156	NCIH2009	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.7593591406338762	[603]	[1771,1642,931]	9	hSpCas9	negative selection	7879169
23049268	23049291	20	+	27260156	NCIH2009	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.39315071275058244	[207]	[560,311,307]	5	hSpCas9	negative selection	7879170
23049399	23049422	20	+	27260156	NCIH2009	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.10941671476265091	[295]	[542,380,433]	1	hSpCas9	negative selection	7879171
23049197	23049220	20	-	27260156	NCIH2009	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.778989926731406	[86]	[369,223,62]	9	hSpCas9	negative selection	7943423
23048567	23048590	20	-	27260156	NCIH2009	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.2429845334901901	[281]	[328,301,366]	-3	hSpCas9	negative selection	7943424
23049340	23049363	20	+	27260156	NCIH2009	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.4471817164442835	[89]	[176,232,103]	6	hSpCas9	negative selection	7943425
23048924	23048947	20	-	27260156	NCIH1373	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	-0.3797792502069191	[603]	[458,549,310,200]	-4	hSpCas9	negative selection	8000420
23049268	23049291	20	+	27260156	NCIH1373	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	1.2174220225255916	[207]	[947,525,432,81]	9	hSpCas9	negative selection	8000421
23049399	23049422	20	+	27260156	NCIH1373	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.4121478802829122	[295]	[674,356,176,161]	4	hSpCas9	negative selection	8000422
23049197	23049220	20	-	27260156	NCIH1373	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	-0.749799491958413	[86]	[44,112,33,7]	-6	hSpCas9	negative selection	8064674
23048567	23048590	20	-	27260156	NCIH1373	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.015232942508140224	[281]	[254,390,340,62]	0	hSpCas9	negative selection	8064675
23049340	23049363	20	+	27260156	NCIH1373	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.5755115126489705	[89]	[125,39,79,8]	-5	hSpCas9	negative selection	8064676
23048924	23048947	20	-	27260156	PATU8902	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.6330989274213494	[603]	[1539,1217,618,2100]	6	hSpCas9	negative selection	8121671
23049268	23049291	20	+	27260156	PATU8902	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.6809708697373658	[207]	[610,530,395,313]	7	hSpCas9	negative selection	8121672
23049399	23049422	20	+	27260156	PATU8902	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.32116023588749776	[295]	[325,470,78,530]	-3	hSpCas9	negative selection	8121673
23049197	23049220	20	-	27260156	PATU8902	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	-0.6977293605269366	[86]	[53,106,18,140]	-6	hSpCas9	negative selection	8185925
23048567	23048590	20	-	27260156	PATU8902	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	0.43177202837878675	[281]	[368,373,740,583]	4	hSpCas9	negative selection	8185926
23049340	23049363	20	+	27260156	PATU8902	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.10873475652482023	[89]	[134,69,67,214]	-1	hSpCas9	negative selection	8185927
23048924	23048947	20	-	27260156	PANC1	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.40772127250762874	[603]	[656,1050,647,492]	6	hSpCas9	negative selection	8242922
23049268	23049291	20	+	27260156	PANC1	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.10128072706487168	[207]	[184,273,162,162]	1	hSpCas9	negative selection	8242923
23049399	23049422	20	+	27260156	PANC1	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.5567743395614884	[295]	[304,624,299,320]	8	hSpCas9	negative selection	8242924
23049197	23049220	20	-	27260156	PANC1	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.47717197121125055	[86]	[110,78,153,70]	7	hSpCas9	negative selection	8307176
23048567	23048590	20	-	27260156	PANC1	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.6198123066772995	[281]	[121,120,249,132]	-7	hSpCas9	negative selection	8307177
23049340	23049363	20	+	27260156	PANC1	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.36446908662990474	[89]	[117,76,87,106]	6	hSpCas9	negative selection	8307178
23048924	23048947	20	-	27260156	PANC0813	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.867955908826828	[603]	[1563,1602,1092,959]	9	hSpCas9	negative selection	8364173
23049268	23049291	20	+	27260156	PANC0813	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.5448577799879958	[207]	[478,392,262,303]	8	hSpCas9	negative selection	8364174
23049399	23049422	20	+	27260156	PANC0813	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.22095984016170017	[295]	[451,333,419,417]	3	hSpCas9	negative selection	8364175
23049197	23049220	20	-	27260156	PANC0813	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	-0.23457930243505087	[86]	[135,57,91,66]	-4	hSpCas9	negative selection	8428427
23048567	23048590	20	-	27260156	PANC0813	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.06603385678795837	[281]	[319,206,317,414]	-1	hSpCas9	negative selection	8428428
23049340	23049363	20	+	27260156	PANC0813	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.18296836559371732	[89]	[176,67,43,90]	-3	hSpCas9	negative selection	8428429
23048924	23048947	20	-	27260156	RDES	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.359142118181005	[603]	[790,833,1018,928]	6	hSpCas9	negative selection	8485424
23049268	23049291	20	+	27260156	RDES	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.5014385427936859	[207]	[281,328,408,339]	7	hSpCas9	negative selection	8485425
23049399	23049422	20	+	27260156	RDES	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.2618899235923268	[295]	[261,369,466,587]	4	hSpCas9	negative selection	8485426
23049197	23049220	20	-	27260156	RDES	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	-0.2581699145835694	[86]	[112,57,78,75]	-4	hSpCas9	negative selection	8549678
23048567	23048590	20	-	27260156	RDES	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.355869043870343	[281]	[140,271,264,369]	-6	hSpCas9	negative selection	8549679
23049340	23049363	20	+	27260156	RDES	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.5401934618673521	[89]	[79,72,208,281]	8	hSpCas9	negative selection	8549680
23048924	23048947	20	-	27260156	PC3	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.4791793277284289	[603]	[549,795,1250,969]	8	hSpCas9	negative selection	8606675
23049268	23049291	20	+	27260156	PC3	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.4967130494371125	[207]	[193,277,408,350]	8	hSpCas9	negative selection	8606676
23049399	23049422	20	+	27260156	PC3	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.26809462209810764	[295]	[169,313,403,151]	-6	hSpCas9	negative selection	8606677
23049197	23049220	20	-	27260156	PC3	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.7568633689753286	[86]	[55,42,556,126]	9	hSpCas9	negative selection	8670929
23048567	23048590	20	-	27260156	PC3	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.6144406944085695	[281]	[141,116,287,230]	-8	hSpCas9	negative selection	8670930
23049340	23049363	20	+	27260156	PC3	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.8678097240115843	[89]	[52,73,338,308]	9	hSpCas9	negative selection	8670931
23048924	23048947	20	-	27260156	PATU8988T	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.6557753123958094	[603]	[1016,776,980,885]	9	hSpCas9	negative selection	8727926
23049268	23049291	20	+	27260156	PATU8988T	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.8144679195083963	[207]	[350,237,395,422]	9	hSpCas9	negative selection	8727927
23049399	23049422	20	+	27260156	PATU8988T	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.42476061627239126	[295]	[297,351,351,543]	7	hSpCas9	negative selection	8727928
23049197	23049220	20	-	27260156	PATU8988T	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.5776711780345791	[86]	[105,121,139,133]	8	hSpCas9	negative selection	8792180
23048567	23048590	20	-	27260156	PATU8988T	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.2965510442748641	[281]	[209,198,310,158]	-5	hSpCas9	negative selection	8792181
23049340	23049363	20	+	27260156	PATU8988T	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.07670427434591609	[89]	[75,107,144,33]	1	hSpCas9	negative selection	8792182
23048924	23048947	20	-	27260156	T47D	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.381465176644287	[603]	[957,854,866,994]	7	hSpCas9	negative selection	8849177
23049268	23049291	20	+	27260156	T47D	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.40483342542661827	[207]	[344,358,274,300]	8	hSpCas9	negative selection	8849178
23049399	23049422	20	+	27260156	T47D	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.003305234996329398	[295]	[406,305,281,386]	0	hSpCas9	negative selection	8849179
23049197	23049220	20	-	27260156	T47D	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.12213591099918153	[86]	[132,112,73,121]	2	hSpCas9	negative selection	8913431
23048567	23048590	20	-	27260156	T47D	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.2643843023231204	[281]	[264,169,312,356]	-5	hSpCas9	negative selection	8913432
23049340	23049363	20	+	27260156	T47D	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.11999403726955071	[89]	[99,165,87,96]	2	hSpCas9	negative selection	8913433
23048924	23048947	20	-	27260156	SU8686	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.6780437595115187	[603]	[904,751,954,1301]	9	hSpCas9	negative selection	8970428
23049268	23049291	20	+	27260156	SU8686	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.40231576174806705	[207]	[250,194,371,287]	6	hSpCas9	negative selection	8970429
23049399	23049422	20	+	27260156	SU8686	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.13306541940707406	[295]	[254,213,285,332]	-2	hSpCas9	negative selection	8970430
23049197	23049220	20	-	27260156	SU8686	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.1514542831844503	[86]	[89,115,96,73]	2	hSpCas9	negative selection	9034682
23048567	23048590	20	-	27260156	SU8686	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.14775274335106314	[281]	[204,362,103,335]	-3	hSpCas9	negative selection	9034683
23049340	23049363	20	+	27260156	SU8686	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.007311270090974098	[89]	[112,85,77,71]	0	hSpCas9	negative selection	9034684
23048924	23048947	20	-	27260156	SKES1	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.39952270745009116	[603]	[835,733,909,698]	7	hSpCas9	negative selection	9091679
23049268	23049291	20	+	27260156	SKES1	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.049886903412845074	[207]	[227,223,233,177]	1	hSpCas9	negative selection	9091680
23049399	23049422	20	+	27260156	SKES1	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.04151541875959719	[295]	[358,318,254,290]	0	hSpCas9	negative selection	9091681
23049197	23049220	20	-	27260156	SKES1	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.016631728977899662	[86]	[54,169,51,79]	0	hSpCas9	negative selection	9155933
23048567	23048590	20	-	27260156	SKES1	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.16287514423033456	[281]	[429,326,131,159]	-4	hSpCas9	negative selection	9155934
23049340	23049363	20	+	27260156	SKES1	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.4964570899494065	[89]	[92,223,78,117]	8	hSpCas9	negative selection	9155935
23048924	23048947	20	-	27260156	TOV112D	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.7048743891022766	[603]	[1206,919,943,876]	9	hSpCas9	negative selection	9212930
23049268	23049291	20	+	27260156	TOV112D	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.5676150771488493	[207]	[329,495,170,285]	8	hSpCas9	negative selection	9212931
23049399	23049422	20	+	27260156	TOV112D	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	0.23363264719418475	[295]	[364,342,346,338]	4	hSpCas9	negative selection	9212932
23049197	23049220	20	-	27260156	TOV112D	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.7982215579761518	[86]	[60,290,217,64]	9	hSpCas9	negative selection	9277184
23048567	23048590	20	-	27260156	TOV112D	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.3666477439072774	[281]	[190,415,169,146]	-6	hSpCas9	negative selection	9277185
23049340	23049363	20	+	27260156	TOV112D	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	-0.3239762856480044	[89]	[48,54,76,99]	-6	hSpCas9	negative selection	9277186
23048924	23048947	20	-	27260156	TC71	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.3892831169190551	[603]	[880,850,765,898]	8	hSpCas9	negative selection	9334181
23049268	23049291	20	+	27260156	TC71	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.41170354234647744	[207]	[309,340,318,209]	8	hSpCas9	negative selection	9334182
23049399	23049422	20	+	27260156	TC71	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.314223512044322	[295]	[283,287,165,286]	-7	hSpCas9	negative selection	9334183
23049197	23049220	20	-	27260156	TC71	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.13841992300788997	[86]	[115,136,113,38]	3	hSpCas9	negative selection	9398435
23048567	23048590	20	-	27260156	TC71	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.36685048569894374	[281]	[202,241,223,271]	-7	hSpCas9	negative selection	9398436
23049340	23049363	20	+	27260156	TC71	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.0653759409938095	[89]	[80,93,120,107]	1	hSpCas9	negative selection	9398437
23048924	23048947	20	-	27260156	TC32	viability	GCCGCCGTCTCGATCACCTACGG	THBD	ENSG00000178726	0.3276194462567901	[603]	[709,496,871,844]	6	hSpCas9	negative selection	9455432
23049268	23049291	20	+	27260156	TC32	viability	GCCGTCGCCGTTCAGTAGCAAGG	THBD	ENSG00000178726	0.6907830622209745	[207]	[304,234,466,292]	9	hSpCas9	negative selection	9455433
23049399	23049422	20	+	27260156	TC32	viability	AGCAGTCGTGCTCGACGCACTGG	THBD	ENSG00000178726	-0.21954933846861113	[295]	[201,155,328,310]	-4	hSpCas9	negative selection	9455434
23049197	23049220	20	-	27260156	TC32	viability	TGCGGCGACCCCAAGCGCCTCGG	THBD	ENSG00000178726	0.7194167126290407	[86]	[98,192,119,93]	9	hSpCas9	negative selection	9519686
23048567	23048590	20	-	27260156	TC32	viability	TACTCGTGCATGTGCGAGACCGG	THBD	ENSG00000178726	-0.1317929182837565	[281]	[192,247,309,214]	-2	hSpCas9	negative selection	9519687
23049340	23049363	20	+	27260156	TC32	viability	CAGTCCGTCGCAGATCTGACTGG	THBD	ENSG00000178726	0.33599613369879133	[89]	[67,90,144,135]	6	hSpCas9	negative selection	9519688
23048049	23048072	20	-	27869803	HPAFII	viability after 27 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.12473321038140872	[1299]	[778,716,NaN]	1	hSpCas9	negative selection	9576664
23048327	23048350	20	-	27869803	HPAFII	viability after 27 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	-0.7459759696144412	[115]	[37,34,NaN]	-5	hSpCas9	negative selection	9576665
23048520	23048543	20	+	27869803	HPAFII	viability after 27 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	-1.2372103955951719	[458]	[175,40,NaN]	-7	hSpCas9	negative selection	9576666
23048834	23048857	20	+	27869803	HPAFII	viability after 27 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	-0.2525865154528606	[301]	[195,80,NaN]	-2	hSpCas9	negative selection	9576667
23049081	23049104	20	+	27869803	HPAFII	viability after 27 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	-0.09359070816545301	[985]	[337,608,NaN]	0	hSpCas9	negative selection	9576668
23048049	23048072	20	-	27869803	HPAFII	viability after 15 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.29891013991443005	[1299]	[2171,1436,NaN]	3	hSpCas9	negative selection	9659113
23048327	23048350	20	-	27869803	HPAFII	viability after 15 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.6404780138814021	[115]	[255,155,NaN]	7	hSpCas9	negative selection	9659114
23048520	23048543	20	+	27869803	HPAFII	viability after 15 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	-0.2605666982069198	[458]	[634,272,NaN]	-3	hSpCas9	negative selection	9659115
23048834	23048857	20	+	27869803	HPAFII	viability after 15 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	0.2690173096994626	[301]	[572,277,NaN]	3	hSpCas9	negative selection	9659116
23049081	23049104	20	+	27869803	HPAFII	viability after 15 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	-0.18249147062114557	[985]	[1164,789,NaN]	-2	hSpCas9	negative selection	9659117
23048049	23048072	20	-	27869803	ASPC1	viability after 36 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.13987050931184708	[2993]	[1652,917,972]	1	hSpCas9	negative selection	9741562
23048327	23048350	20	-	27869803	ASPC1	viability after 36 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.5216977467260194	[299]	[146,152,148]	5	hSpCas9	negative selection	9741563
23048520	23048543	20	+	27869803	ASPC1	viability after 36 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.5962692021005386	[1248]	[874,581,561]	6	hSpCas9	negative selection	9741564
23048834	23048857	20	+	27869803	ASPC1	viability after 36 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	-0.2180288771389378	[758]	[37,526,120]	-2	hSpCas9	negative selection	9741565
23049081	23049104	20	+	27869803	ASPC1	viability after 36 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.5646612139871325	[1830]	[1175,1459,364]	5	hSpCas9	negative selection	9741566
23048049	23048072	20	-	27869803	PATU8988S	viability after 35 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.3496333278294874	[2448]	[1398,1113,NaN]	4	hSpCas9	negative selection	9824011
23048327	23048350	20	-	27869803	PATU8988S	viability after 35 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.3412019210331089	[379]	[140,246,NaN]	4	hSpCas9	negative selection	9824012
23048520	23048543	20	+	27869803	PATU8988S	viability after 35 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	0.06365636761224369	[1222]	[638,389,NaN]	0	hSpCas9	negative selection	9824013
23048834	23048857	20	+	27869803	PATU8988S	viability after 35 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	-0.12521104286058848	[685]	[173,332,NaN]	-1	hSpCas9	negative selection	9824014
23049081	23049104	20	+	27869803	PATU8988S	viability after 35 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.28548135670821595	[1534]	[971,533,NaN]	3	hSpCas9	negative selection	9824015
23048049	23048072	20	-	27869803	PATU8988S	viability after 31 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.4758518449375435	[2448]	[1204,1552,NaN]	6	hSpCas9	negative selection	9906460
23048327	23048350	20	-	27869803	PATU8988S	viability after 31 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	0.4376866140133969	[379]	[140,286,NaN]	5	hSpCas9	negative selection	9906461
23048520	23048543	20	+	27869803	PATU8988S	viability after 31 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	-0.014234687986438788	[1222]	[459,511,NaN]	0	hSpCas9	negative selection	9906462
23048834	23048857	20	+	27869803	PATU8988S	viability after 31 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	-0.02641118880271065	[685]	[151,416,NaN]	0	hSpCas9	negative selection	9906463
23049081	23049104	20	+	27869803	PATU8988S	viability after 31 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	0.42082281908463437	[1534]	[887,731,NaN]	5	hSpCas9	negative selection	9906464
23048049	23048072	20	-	27869803	HPAFII	viability after 35 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.43961919916772807	[1299]	[623,1194,NaN]	3	hSpCas9	negative selection	9988909
23048327	23048350	20	-	27869803	HPAFII	viability after 35 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	-0.03263547364595376	[115]	[55,58,NaN]	0	hSpCas9	negative selection	9988910
23048520	23048543	20	+	27869803	HPAFII	viability after 35 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	-1.1727097563581703	[458]	[135,65,NaN]	-6	hSpCas9	negative selection	9988911
23048834	23048857	20	+	27869803	HPAFII	viability after 35 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	-0.02154134602021679	[301]	[215,76,NaN]	0	hSpCas9	negative selection	9988912
23049081	23049104	20	+	27869803	HPAFII	viability after 35 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	-0.2422155571966078	[985]	[207,662,NaN]	-1	hSpCas9	negative selection	9988913
23048049	23048072	20	-	27869803	HPAFII	viability after 31 days	CGACTGTGACTCCGGCAAGGTGG	THBD	ENSG00000178726	0.29019467534994803	[1299]	[682,1119,NaN]	2	hSpCas9	negative selection	10071358
23048327	23048350	20	-	27869803	HPAFII	viability after 31 days	TACCTCTGCGTCTGCGCCGAGGG	THBD	ENSG00000178726	-0.1494967609707465	[115]	[62,53,NaN]	-1	hSpCas9	negative selection	10071359
23048520	23048543	20	+	27869803	HPAFII	viability after 31 days	AGTCATCCACGTCCTCGCACCGG	THBD	ENSG00000178726	-1.052872693709861	[458]	[138,107,NaN]	-6	hSpCas9	negative selection	10071360
23048834	23048857	20	+	27869803	HPAFII	viability after 31 days	CACATTAGCTGTAAGCCGAGGGG	THBD	ENSG00000178726	-0.11336947068819447	[301]	[182,127,NaN]	-1	hSpCas9	negative selection	10071361
23049081	23049104	20	+	27869803	HPAFII	viability after 31 days	CGGAGACAGCGACGCACAACGGG	THBD	ENSG00000178726	-0.30138625190848267	[985]	[326,581,NaN]	-2	hSpCas9	negative selection	10071362
23049344	23049367	20	-	28162770	P31FUJ	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.8648737266413145	[206]	[442]	8	hSpCas9	negative selection	10250198
23049171	23049194	20	+	28162770	P31FUJ	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	0.21399785724925308	[145]	[198]	2	hSpCas9	negative selection	10250199
23049228	23049251	20	+	28162770	P31FUJ	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	-0.18370765488620888	[259]	[268]	-2	hSpCas9	negative selection	10250200
23049061	23049084	20	+	28162770	P31FUJ	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-1.1503400442224057	[67]	[35]	-7	hSpCas9	negative selection	10250201
23049021	23049044	20	-	28162770	P31FUJ	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	0.9278612271703632	[190]	[426]	9	hSpCas9	negative selection	10250202
23048923	23048946	20	+	28162770	P31FUJ	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	-0.9697677985805846	[69]	[41]	-6	hSpCas9	negative selection	10250203
23048613	23048636	20	+	28162770	P31FUJ	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	0.4236396847267165	[209]	[330]	5	hSpCas9	negative selection	10250204
23048474	23048497	20	+	28162770	P31FUJ	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.6026862903296735	[398]	[711]	7	hSpCas9	negative selection	10250205
23048042	23048065	20	-	28162770	P31FUJ	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-0.2328022044143787	[19]	[19]	-2	hSpCas9	negative selection	10250206
23049306	23049329	20	-	28162770	P31FUJ	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	-0.1825435939787523	[676]	[700]	-2	hSpCas9	negative selection	10250207
23049344	23049367	20	-	28162770	TF1	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10419564
23049171	23049194	20	+	28162770	TF1	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	NaN	[NaN]	[301]	1	hSpCas9	negative selection	10419565
23049228	23049251	20	+	28162770	TF1	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	NaN	[NaN]	[182]	1	hSpCas9	negative selection	10419566
23049061	23049084	20	+	28162770	TF1	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10419567
23049021	23049044	20	-	28162770	TF1	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10419568
23048923	23048946	20	+	28162770	TF1	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10419569
23048613	23048636	20	+	28162770	TF1	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	NaN	[NaN]	[253]	1	hSpCas9	negative selection	10419570
23048474	23048497	20	+	28162770	TF1	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	NaN	[NaN]	[484]	1	hSpCas9	negative selection	10419571
23048042	23048065	20	-	28162770	TF1	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10419572
23049306	23049329	20	-	28162770	TF1	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	NaN	[NaN]	[441]	1	hSpCas9	negative selection	10419573
23049344	23049367	20	-	28162770	SKM1	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	-0.2444566688633325	[64]	[96]	-2	hSpCas9	negative selection	10588930
23049171	23049194	20	+	28162770	SKM1	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	0.1779983019779947	[23]	[47]	1	hSpCas9	negative selection	10588931
23049228	23049251	20	+	28162770	SKM1	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.2560008139792676	[62]	[132]	2	hSpCas9	negative selection	10588932
23049061	23049084	20	+	28162770	SKM1	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-0.5444677224930966	[32]	[39]	-4	hSpCas9	negative selection	10588933
23049021	23049044	20	-	28162770	SKM1	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	0.6652641288120174	[55]	[156]	6	hSpCas9	negative selection	10588934
23048923	23048946	20	+	28162770	SKM1	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	0.0625210845580586	[12]	[23]	0	hSpCas9	negative selection	10588935
23048613	23048636	20	+	28162770	SKM1	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	-0.687072117935897	[50]	[55]	-5	hSpCas9	negative selection	10588936
23048474	23048497	20	+	28162770	SKM1	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.38235680048418086	[91]	[211]	4	hSpCas9	negative selection	10588937
23048042	23048065	20	-	28162770	SKM1	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-3.143929792909368	[4]	[0]	-9	hSpCas9	negative selection	10588938
23049306	23049329	20	-	28162770	SKM1	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.5709129903586982	[114]	[301]	5	hSpCas9	negative selection	10588939
23049344	23049367	20	-	28162770	SKM1	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	-0.2444566688633325	[64]	[96]	-2	hSpCas9	negative selection	10758296
23049171	23049194	20	+	28162770	SKM1	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	0.1779983019779947	[23]	[47]	1	hSpCas9	negative selection	10758297
23049228	23049251	20	+	28162770	SKM1	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.2560008139792676	[62]	[132]	2	hSpCas9	negative selection	10758298
23049061	23049084	20	+	28162770	SKM1	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-0.5444677224930966	[32]	[39]	-4	hSpCas9	negative selection	10758299
23049021	23049044	20	-	28162770	SKM1	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	0.6652641288120174	[55]	[156]	6	hSpCas9	negative selection	10758300
23048923	23048946	20	+	28162770	SKM1	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	0.0625210845580586	[12]	[23]	0	hSpCas9	negative selection	10758301
23048613	23048636	20	+	28162770	SKM1	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	-0.687072117935897	[50]	[55]	-5	hSpCas9	negative selection	10758302
23048474	23048497	20	+	28162770	SKM1	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.38235680048418086	[91]	[211]	4	hSpCas9	negative selection	10758303
23048042	23048065	20	-	28162770	SKM1	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-3.143929792909368	[4]	[0]	-9	hSpCas9	negative selection	10758304
23049306	23049329	20	-	28162770	SKM1	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.5709129903586982	[114]	[301]	5	hSpCas9	negative selection	10758305
23049344	23049367	20	-	28162770	PL21	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	1.20013961448932	[179]	[179]	8	hSpCas9	negative selection	10927662
23049171	23049194	20	+	28162770	PL21	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	0.015715043351892888	[99]	[43]	0	hSpCas9	negative selection	10927663
23049228	23049251	20	+	28162770	PL21	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	-0.336527329191055	[234]	[80]	-2	hSpCas9	negative selection	10927664
23049061	23049084	20	+	28162770	PL21	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-1.667756849503335	[72]	[9]	-8	hSpCas9	negative selection	10927665
23049021	23049044	20	-	28162770	PL21	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	0.9163466484887289	[195]	[160]	7	hSpCas9	negative selection	10927666
23048923	23048946	20	+	28162770	PL21	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	-1.247319362481901	[59]	[10]	-7	hSpCas9	negative selection	10927667
23048613	23048636	20	+	28162770	PL21	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	-0.7747694045478494	[113]	[28]	-5	hSpCas9	negative selection	10927668
23048474	23048497	20	+	28162770	PL21	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.03129084960634698	[334]	[148]	0	hSpCas9	negative selection	10927669
23048042	23048065	20	-	28162770	PL21	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-2.7998603855106805	[15]	[0]	-9	hSpCas9	negative selection	10927670
23049306	23049329	20	-	28162770	PL21	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.10195922055041651	[455]	[212]	0	hSpCas9	negative selection	10927671
23049344	23049367	20	-	28162770	P31FUJ	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.8648737266413145	[206]	[442]	8	hSpCas9	negative selection	11097028
23049171	23049194	20	+	28162770	P31FUJ	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	0.21399785724925308	[145]	[198]	2	hSpCas9	negative selection	11097029
23049228	23049251	20	+	28162770	P31FUJ	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	-0.18370765488620888	[259]	[268]	-2	hSpCas9	negative selection	11097030
23049061	23049084	20	+	28162770	P31FUJ	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-1.1503400442224057	[67]	[35]	-7	hSpCas9	negative selection	11097031
23049021	23049044	20	-	28162770	P31FUJ	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	0.9278612271703632	[190]	[426]	9	hSpCas9	negative selection	11097032
23048923	23048946	20	+	28162770	P31FUJ	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	-0.9697677985805846	[69]	[41]	-6	hSpCas9	negative selection	11097033
23048613	23048636	20	+	28162770	P31FUJ	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	0.4236396847267165	[209]	[330]	5	hSpCas9	negative selection	11097034
23048474	23048497	20	+	28162770	P31FUJ	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.6026862903296735	[398]	[711]	7	hSpCas9	negative selection	11097035
23048042	23048065	20	-	28162770	P31FUJ	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-0.2328022044143787	[19]	[19]	-2	hSpCas9	negative selection	11097036
23049306	23049329	20	-	28162770	P31FUJ	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	-0.1825435939787523	[676]	[700]	-2	hSpCas9	negative selection	11097037
23049344	23049367	20	-	28162770	OCIAML5	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	-0.9556892019381544	[201]	[187]	-5	hSpCas9	negative selection	11266394
23049171	23049194	20	+	28162770	OCIAML5	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	0.4759876268202069	[93]	[235]	4	hSpCas9	negative selection	11266395
23049228	23049251	20	+	28162770	OCIAML5	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.8613122029845933	[110]	[363]	7	hSpCas9	negative selection	11266396
23049061	23049084	20	+	28162770	OCIAML5	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-1.4650434477547498	[25]	[16]	-7	hSpCas9	negative selection	11266397
23049021	23049044	20	-	28162770	OCIAML5	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	0.591281324438224	[81]	[222]	5	hSpCas9	negative selection	11266398
23048923	23048946	20	+	28162770	OCIAML5	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	-1.2995255478352181	[29]	[21]	-6	hSpCas9	negative selection	11266399
23048613	23048636	20	+	28162770	OCIAML5	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	-1.1988693343903885	[116]	[91]	-6	hSpCas9	negative selection	11266400
23048474	23048497	20	+	28162770	OCIAML5	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.7260746640011452	[211]	[632]	6	hSpCas9	negative selection	11266401
23048042	23048065	20	-	28162770	OCIAML5	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-0.6110584713602019	[10]	[12]	-4	hSpCas9	negative selection	11266402
23049306	23049329	20	-	28162770	OCIAML5	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	1.0069211196089294	[246]	[895]	8	hSpCas9	negative selection	11266403
23049344	23049367	20	-	28162770	EOL1	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.06771350175640739	[392]	[216]	0	hSpCas9	negative selection	11435760
23049171	23049194	20	+	28162770	EOL1	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	0.37353260277271594	[125]	[85]	3	hSpCas9	negative selection	11435761
23049228	23049251	20	+	28162770	EOL1	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.2621537840053282	[420]	[265]	2	hSpCas9	negative selection	11435762
23049061	23049084	20	+	28162770	EOL1	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-1.8124178225956717	[159]	[23]	-8	hSpCas9	negative selection	11435763
23049021	23049044	20	-	28162770	EOL1	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	-0.15998573864113327	[368]	[173]	-1	hSpCas9	negative selection	11435764
23048923	23048946	20	+	28162770	EOL1	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	-1.7336637111812603	[100]	[15]	-8	hSpCas9	negative selection	11435765
23048613	23048636	20	+	28162770	EOL1	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	1.037441827976468	[171]	[185]	8	hSpCas9	negative selection	11435766
23048474	23048497	20	+	28162770	EOL1	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.25896681064109384	[459]	[289]	2	hSpCas9	negative selection	11435767
23048042	23048065	20	-	28162770	EOL1	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-0.3292088206752486	[30]	[12]	-2	hSpCas9	negative selection	11435768
23049306	23049329	20	-	28162770	EOL1	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.9695575064881006	[567]	[585]	8	hSpCas9	negative selection	11435769
23049344	23049367	20	-	28162770	MOLM13	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.23973001698924445	[375]	[320]	1	hSpCas9	negative selection	11605126
23049171	23049194	20	+	28162770	MOLM13	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	-0.0964628395012912	[138]	[93]	0	hSpCas9	negative selection	11605127
23049228	23049251	20	+	28162770	MOLM13	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.04126390799052322	[249]	[185]	0	hSpCas9	negative selection	11605128
23049061	23049084	20	+	28162770	MOLM13	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	0.6967080720404595	[63]	[74]	5	hSpCas9	negative selection	11605129
23049021	23049044	20	-	28162770	MOLM13	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	1.5200572074098342	[257]	[534]	9	hSpCas9	negative selection	11605130
23048923	23048946	20	+	28162770	MOLM13	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	1.4869982044922834	[74]	[151]	9	hSpCas9	negative selection	11605131
23048613	23048636	20	+	28162770	MOLM13	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	0.0584984454068771	[169]	[127]	0	hSpCas9	negative selection	11605132
23048474	23048497	20	+	28162770	MOLM13	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.7278434551768351	[546]	[654]	5	hSpCas9	negative selection	11605133
23048042	23048065	20	-	28162770	MOLM13	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-3.232550336596514	[12]	[0]	-8	hSpCas9	negative selection	11605134
23049306	23049329	20	-	28162770	MOLM13	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.9964067352759916	[555]	[801]	7	hSpCas9	negative selection	11605135
23049344	23049367	20	-	28162770	HEL	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.7191908924382302	[293]	[309]	6	hSpCas9	negative selection	11774492
23049171	23049194	20	+	28162770	HEL	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	-0.7828679089886741	[136]	[50]	-5	hSpCas9	negative selection	11774493
23049228	23049251	20	+	28162770	HEL	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.30493665776459083	[296]	[234]	2	hSpCas9	negative selection	11774494
23049061	23049084	20	+	28162770	HEL	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-0.9422236687207992	[104]	[34]	-5	hSpCas9	negative selection	11774495
23049021	23049044	20	-	28162770	HEL	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	0.9942112025017346	[231]	[295]	8	hSpCas9	negative selection	11774496
23048923	23048946	20	+	28162770	HEL	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	-0.686568793252603	[97]	[38]	-4	hSpCas9	negative selection	11774497
23048613	23048636	20	+	28162770	HEL	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	1.1890208645574531	[125]	[183]	9	hSpCas9	negative selection	11774498
23048474	23048497	20	+	28162770	HEL	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	-0.1221327587357336	[434]	[255]	-1	hSpCas9	negative selection	11774499
23048042	23048065	20	-	28162770	HEL	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-1.0577008861407355	[12]	[3]	-6	hSpCas9	negative selection	11774500
23049306	23049329	20	-	28162770	HEL	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.7676173536657347	[552]	[602]	6	hSpCas9	negative selection	11774501
23049344	23049367	20	-	28162770	MV411	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.7744168673975229	[219]	[316]	7	hSpCas9	negative selection	11943858
23049171	23049194	20	+	28162770	MV411	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	1.2398243666729	[94]	[188]	9	hSpCas9	negative selection	11943859
23049228	23049251	20	+	28162770	MV411	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	1.0812205981180245	[169]	[302]	8	hSpCas9	negative selection	11943860
23049061	23049084	20	+	28162770	MV411	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	0.22574247968345618	[66]	[65]	2	hSpCas9	negative selection	11943861
23049021	23049044	20	-	28162770	MV411	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	-0.5137755896301082	[199]	[117]	-4	hSpCas9	negative selection	11943862
23048923	23048946	20	+	28162770	MV411	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	-0.015596855051018377	[41]	[34]	0	hSpCas9	negative selection	11943863
23048613	23048636	20	+	28162770	MV411	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	0.21769020738872324	[97]	[95]	2	hSpCas9	negative selection	11943864
23048474	23048497	20	+	28162770	MV411	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.6301196767492339	[371]	[484]	6	hSpCas9	negative selection	11943865
23048042	23048065	20	-	28162770	MV411	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-4.074490544104587	[19]	[0]	-9	hSpCas9	negative selection	11943866
23049306	23049329	20	-	28162770	MV411	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.25852104991179137	[388]	[391]	2	hSpCas9	negative selection	11943867
23049344	23049367	20	-	28162770	MONOMAC1	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	-0.30173422572624703	[99]	[92]	-3	hSpCas9	negative selection	12113224
23049171	23049194	20	+	28162770	MONOMAC1	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	-0.8226413322780559	[53]	[34]	-6	hSpCas9	negative selection	12113225
23049228	23049251	20	+	28162770	MONOMAC1	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.17893108754069786	[130]	[169]	1	hSpCas9	negative selection	12113226
23049061	23049084	20	+	28162770	MONOMAC1	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-2.059533323309619	[39]	[10]	-9	hSpCas9	negative selection	12113227
23049021	23049044	20	-	28162770	MONOMAC1	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	-0.3020064066610963	[113]	[105]	-3	hSpCas9	negative selection	12113228
23048923	23048946	20	+	28162770	MONOMAC1	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	-0.07504632268094324	[33]	[36]	0	hSpCas9	negative selection	12113229
23048613	23048636	20	+	28162770	MONOMAC1	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	0.10382963229997888	[68]	[84]	1	hSpCas9	negative selection	12113230
23048474	23048497	20	+	28162770	MONOMAC1	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.2868681497576666	[270]	[378]	3	hSpCas9	negative selection	12113231
23048042	23048065	20	-	28162770	MONOMAC1	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-2.071505964975695	[10]	[2]	-9	hSpCas9	negative selection	12113232
23049306	23049329	20	-	28162770	MONOMAC1	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	-0.8430287811782695	[337]	[215]	-6	hSpCas9	negative selection	12113233
23049344	23049367	20	-	28162770	OCIAML2	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.9407964204843038	[49]	[531]	8	hSpCas9	negative selection	12282590
23049171	23049194	20	+	28162770	OCIAML2	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	1.3811192161738965	[15]	[230]	9	hSpCas9	negative selection	12282591
23049228	23049251	20	+	28162770	OCIAML2	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	0.48714193936854133	[38]	[302]	5	hSpCas9	negative selection	12282592
23049061	23049084	20	+	28162770	OCIAML2	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-1.2482374039057134	[11]	[27]	-7	hSpCas9	negative selection	12282593
23049021	23049044	20	-	28162770	OCIAML2	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	-0.7019553713486171	[53]	[183]	-5	hSpCas9	negative selection	12282594
23048923	23048946	20	+	28162770	OCIAML2	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	-0.2900575796003402	[14]	[67]	-2	hSpCas9	negative selection	12282595
23048613	23048636	20	+	28162770	OCIAML2	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	-1.4181624053480257	[26]	[55]	-7	hSpCas9	negative selection	12282596
23048474	23048497	20	+	28162770	OCIAML2	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.09542421292893044	[63]	[378]	0	hSpCas9	negative selection	12282597
23048042	23048065	20	-	28162770	OCIAML2	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	-2.8856673245210054	[3]	[2]	-9	hSpCas9	negative selection	12282598
23049306	23049329	20	-	28162770	OCIAML2	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.344433191950706	[79]	[562]	3	hSpCas9	negative selection	12282599
23049344	23049367	20	-	28162770	OCIAML3	viability	AATGCCAGTCAGATCTGCGACGG	THBD	ENSG00000178726	0.18560229125053682	[59]	[205]	1	hSpCas9	negative selection	12451956
23049171	23049194	20	+	28162770	OCIAML3	viability	TAACCCACTGGAAGCCGCGCAGG	THBD	ENSG00000178726	1.5986374376182328	[27]	[255]	9	hSpCas9	negative selection	12451957
23049228	23049251	20	+	28162770	OCIAML3	viability	GCAGCTGCAGGCCGATCCAGAGG	THBD	ENSG00000178726	1.0312187306107203	[52]	[326]	8	hSpCas9	negative selection	12451958
23049061	23049084	20	+	28162770	OCIAML3	viability	GGGCACAGTGGCCTCAGCAGCGG	THBD	ENSG00000178726	-0.4510496864821203	[23]	[52]	-3	hSpCas9	negative selection	12451959
23049021	23049044	20	-	28162770	OCIAML3	viability	GGAGCAGCAGTGCGAAGTGAAGG	THBD	ENSG00000178726	-0.055268156363652565	[73]	[214]	0	hSpCas9	negative selection	12451960
23048923	23048946	20	+	28162770	OCIAML3	viability	GCCGTAGGTGATCGAGACGGCGG	THBD	ENSG00000178726	0.46488604872940553	[11]	[49]	4	hSpCas9	negative selection	12451961
23048613	23048636	20	+	28162770	OCIAML3	viability	GAACGCAGAAGTGCTCGCAGAGG	THBD	ENSG00000178726	-0.21849850523195669	[36]	[95]	-2	hSpCas9	negative selection	12451962
23048474	23048497	20	+	28162770	OCIAML3	viability	TGTGTGTTGACACAGCGCTGCGG	THBD	ENSG00000178726	0.8077084804568466	[101]	[538]	7	hSpCas9	negative selection	12451963
23048042	23048065	20	-	28162770	OCIAML3	viability	GACTCCGGCAAGGTGGACGGTGG	THBD	ENSG00000178726	1.92955431573285	[1]	[22]	9	hSpCas9	negative selection	12451964
23049306	23049329	20	-	28162770	OCIAML3	viability	AATGACAGTGCGCTCCTCGGTGG	THBD	ENSG00000178726	0.5824189270601043	[122]	[555]	5	hSpCas9	negative selection	12451965