Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7058
• Symbol:THBS2
• Description:thrombospondin 2

DataSource: http://genomecrispr.dkfz.de/#!/results/THBS2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
169222200	169222223	6	-	26472758	Jiyoye	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	2.7697454608905816	[20]	[107]	9	hSpCas9	negative selection	165065
169237184	169237207	6	-	26472758	Jiyoye	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	0.2023555896173753	[135]	[117]	1	hSpCas9	negative selection	165066
169248689	169248712	6	+	26472758	Jiyoye	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	1.4346561179279806	[51]	[105]	8	hSpCas9	negative selection	165067
169248557	169248580	6	-	26472758	Jiyoye	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	-0.0614223625234982	[374]	[270]	0	hSpCas9	negative selection	165068
169246199	169246222	6	-	26472758	Jiyoye	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	1.0269033003877064	[40]	[62]	6	hSpCas9	negative selection	165069
169241879	169241902	6	+	26472758	Jiyoye	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	1.1238685806458186	[128]	[211]	7	hSpCas9	negative selection	165070
169241818	169241841	6	-	26472758	Jiyoye	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.25601130817222273	[190]	[171]	2	hSpCas9	negative selection	165071
169239640	169239663	6	+	26472758	Jiyoye	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.5337077874348053	[119]	[130]	4	hSpCas9	negative selection	165072
169237331	169237354	6	-	26472758	Jiyoye	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	1.9052022454557487	[56]	[160]	8	hSpCas9	negative selection	165073
169237302	169237325	6	+	26472758	Jiyoye	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	-0.577874277028155	[191]	[96]	-4	hSpCas9	negative selection	165074
169222200	169222223	6	-	26472758	KBM7	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	0.16157592907706086	[265,164]	[107,113]	1	hSpCas9	negative selection	356183
169237184	169237207	6	-	26472758	KBM7	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	-0.036636703783550995	[372,268]	[127,160]	0	hSpCas9	negative selection	356184
169248689	169248712	6	+	26472758	KBM7	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	0.36359529599650203	[322,233]	[193,141]	4	hSpCas9	negative selection	356185
169248557	169248580	6	-	26472758	KBM7	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	0.9218626219207287	[1127,1078]	[1182,808]	8	hSpCas9	negative selection	356186
169246199	169246222	6	-	26472758	KBM7	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	0.46744006767579893	[524,332]	[332,220]	5	hSpCas9	negative selection	356187
169241879	169241902	6	+	26472758	KBM7	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.6255140000879933	[697,379]	[369,390]	6	hSpCas9	negative selection	356188
169241818	169241841	6	-	26472758	KBM7	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.49217945645335726	[499,443]	[381,248]	5	hSpCas9	negative selection	356189
169239640	169239663	6	+	26472758	KBM7	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.2675417861377759	[867,512]	[392,372]	2	hSpCas9	negative selection	356190
169237331	169237354	6	-	26472758	KBM7	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.830783137984734	[521,480]	[434,405]	8	hSpCas9	negative selection	356191
169237302	169237325	6	+	26472758	KBM7	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	1.1723823592661642	[662,485]	[645,562]	9	hSpCas9	negative selection	356192
169222200	169222223	6	-	26472758	Raji	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	0.7088341588833246	[115]	[43]	6	hSpCas9	negative selection	547301
169237184	169237207	6	-	26472758	Raji	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	-0.29386701217516853	[242]	[45]	-2	hSpCas9	negative selection	547302
169248689	169248712	6	+	26472758	Raji	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	0.4721478281712195	[145]	[46]	4	hSpCas9	negative selection	547303
169248557	169248580	6	-	26472758	Raji	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	-0.026472211361191045	[473]	[107]	0	hSpCas9	negative selection	547304
169246199	169246222	6	-	26472758	Raji	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	-0.16347037491949368	[221]	[45]	-1	hSpCas9	negative selection	547305
169241879	169241902	6	+	26472758	Raji	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.5441979770476949	[262]	[88]	5	hSpCas9	negative selection	547306
169241818	169241841	6	-	26472758	Raji	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.11195626516342361	[314]	[78]	1	hSpCas9	negative selection	547307
169239640	169239663	6	+	26472758	Raji	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	-0.18959820238353203	[343]	[69]	-2	hSpCas9	negative selection	547308
169237331	169237354	6	-	26472758	Raji	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.32377721608860427	[240]	[69]	3	hSpCas9	negative selection	547309
169237302	169237325	6	+	26472758	Raji	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	0.3741700760685009	[255]	[76]	3	hSpCas9	negative selection	547310
169222200	169222223	6	-	26472758	K562	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	1.2308721958284992	[106]	[211]	9	hSpCas9	negative selection	738419
169237184	169237207	6	-	26472758	K562	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	-0.10107783835931983	[215]	[169]	0	hSpCas9	negative selection	738420
169248689	169248712	6	+	26472758	K562	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	-0.723872412606215	[269]	[137]	-4	hSpCas9	negative selection	738421
169248557	169248580	6	-	26472758	K562	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	1.0846050421914235	[781]	[1399]	8	hSpCas9	negative selection	738422
169246199	169246222	6	-	26472758	K562	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	-0.6210391489547256	[265]	[145]	-4	hSpCas9	negative selection	738423
169241879	169241902	6	+	26472758	K562	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.45592283286015867	[493]	[571]	3	hSpCas9	negative selection	738424
169241818	169241841	6	-	26472758	K562	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.5202050409090886	[412]	[499]	4	hSpCas9	negative selection	738425
169239640	169239663	6	+	26472758	K562	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.45339063324057316	[647]	[748]	3	hSpCas9	negative selection	738426
169237331	169237354	6	-	26472758	K562	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	1.439651178186223	[382]	[876]	9	hSpCas9	negative selection	738427
169237302	169237325	6	+	26472758	K562	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	0.3235473774509863	[336]	[355]	2	hSpCas9	negative selection	738428
169237790	169237813	6	-	26627737	DLD1	viability	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	-0.47099752479034107	[744]	[243,166,102]	-5	hSpCas9	negative selection	831337
169239619	169239642	6	+	26627737	DLD1	viability	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	0.11095464695951485	[330]	[147,93,94]	1	hSpCas9	negative selection	831338
169240559	169240582	6	+	26627737	DLD1	viability	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.8063537007813051	[454]	[224,236,278]	7	hSpCas9	negative selection	831339
169241761	169241784	6	-	26627737	DLD1	viability	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.257185413252021	[275]	[115,96,96]	2	hSpCas9	negative selection	831340
169248814	169248837	6	+	26627737	DLD1	viability	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.87096053765011	[334]	[103,418,78]	8	hSpCas9	negative selection	831341
169250732	169250755	6	-	26627737	DLD1	viability	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.01460929821469259	[1418]	[454,545,360]	0	hSpCas9	negative selection	831342
169237790	169237813	6	-	26627737	GBM cells	viability after 5 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.2690671256894579	[252]	[177,148]	4	hSpCas9	negative selection	913652
169239619	169239642	6	+	26627737	GBM cells	viability after 5 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	1.1201671765096655	[180]	[222,198]	9	hSpCas9	negative selection	913653
169240559	169240582	6	+	26627737	GBM cells	viability after 5 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.23056097450849977	[502]	[290,341]	3	hSpCas9	negative selection	913654
169241761	169241784	6	-	26627737	GBM cells	viability after 5 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	-0.16248666977845772	[191]	[99,83]	-3	hSpCas9	negative selection	913655
169248814	169248837	6	+	26627737	GBM cells	viability after 5 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.4294285915844653	[179]	[115,143]	6	hSpCas9	negative selection	913656
169250732	169250755	6	-	26627737	GBM cells	viability after 5 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.41527256160781817	[322]	[248,212]	6	hSpCas9	negative selection	913657
169237790	169237813	6	-	26627737	GBM cells	viability after 13 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.15080079856585749	[252]	[190,120]	2	hSpCas9	negative selection	995967
169239619	169239642	6	+	26627737	GBM cells	viability after 13 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	1.298180540342539	[180]	[219,258]	9	hSpCas9	negative selection	995968
169240559	169240582	6	+	26627737	GBM cells	viability after 13 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.10161243382261542	[502]	[299,286]	1	hSpCas9	negative selection	995969
169241761	169241784	6	-	26627737	GBM cells	viability after 13 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	-0.1847269560141851	[191]	[89,92]	-2	hSpCas9	negative selection	995970
169248814	169248837	6	+	26627737	GBM cells	viability after 13 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	-0.04672198083261314	[179]	[93,94]	0	hSpCas9	negative selection	995971
169250732	169250755	6	-	26627737	GBM cells	viability after 13 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.30287660142703093	[322]	[256,182]	4	hSpCas9	negative selection	995972
169237790	169237813	6	-	26627737	GBM cells	viability after 21 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	-0.6166180027953648	[252]	[97,81]	-5	hSpCas9	negative selection	1078282
169239619	169239642	6	+	26627737	GBM cells	viability after 21 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	1.420037620817038	[180]	[259,265]	9	hSpCas9	negative selection	1078283
169240559	169240582	6	+	26627737	GBM cells	viability after 21 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.6032110635949652	[502]	[423,406]	6	hSpCas9	negative selection	1078284
169241761	169241784	6	-	26627737	GBM cells	viability after 21 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.17369643318568873	[191]	[113,120]	1	hSpCas9	negative selection	1078285
169248814	169248837	6	+	26627737	GBM cells	viability after 21 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.3956255481851877	[179]	[136,120]	4	hSpCas9	negative selection	1078286
169250732	169250755	6	-	26627737	GBM cells	viability after 21 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.20138698502341273	[322]	[218,185]	2	hSpCas9	negative selection	1078287
169237790	169237813	6	-	26627737	RPE1	viability after 9 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.6795358599061553	[520]	[224,307]	4	hSpCas9	negative selection	1160597
169239619	169239642	6	+	26627737	RPE1	viability after 9 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	1.052969756051658	[472]	[239,393]	6	hSpCas9	negative selection	1160598
169240559	169240582	6	+	26627737	RPE1	viability after 9 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.8194059154867722	[1296]	[461,1044]	5	hSpCas9	negative selection	1160599
169241761	169241784	6	-	26627737	RPE1	viability after 9 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.765880242110518	[628]	[195,513]	5	hSpCas9	negative selection	1160600
169248814	169248837	6	+	26627737	RPE1	viability after 9 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	3.3629153503776696	[110]	[181,583]	9	hSpCas9	negative selection	1160601
169250732	169250755	6	-	26627737	RPE1	viability after 9 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.0760994361770766	[1386]	[362,579]	0	hSpCas9	negative selection	1160602
169237790	169237813	6	-	26627737	RPE1	viability after 12 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.5121462573816855	[520]	[237,158]	3	hSpCas9	negative selection	1242912
169239619	169239642	6	+	26627737	RPE1	viability after 12 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	1.3432508194679746	[472]	[268,378]	7	hSpCas9	negative selection	1242913
169240559	169240582	6	+	26627737	RPE1	viability after 12 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.8962703075421113	[1296]	[361,951]	5	hSpCas9	negative selection	1242914
169241761	169241784	6	-	26627737	RPE1	viability after 12 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.710107241828807	[628]	[206,349]	4	hSpCas9	negative selection	1242915
169248814	169248837	6	+	26627737	RPE1	viability after 12 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	2.6534312682801677	[110]	[140,236]	9	hSpCas9	negative selection	1242916
169250732	169250755	6	-	26627737	RPE1	viability after 12 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.09052367041761611	[1386]	[320,476]	0	hSpCas9	negative selection	1242917
169237790	169237813	6	-	26627737	RPE1	viability after 15 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.8534860615908861	[520]	[305,227]	5	hSpCas9	negative selection	1325227
169239619	169239642	6	+	26627737	RPE1	viability after 15 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	0.7781894937971645	[472]	[146,308]	5	hSpCas9	negative selection	1325228
169240559	169240582	6	+	26627737	RPE1	viability after 15 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.9962094610464948	[1296]	[345,1103]	6	hSpCas9	negative selection	1325229
169241761	169241784	6	-	26627737	RPE1	viability after 15 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.6344683533002551	[628]	[207,341]	4	hSpCas9	negative selection	1325230
169248814	169248837	6	+	26627737	RPE1	viability after 15 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	2.541301700783317	[110]	[166,197]	9	hSpCas9	negative selection	1325231
169250732	169250755	6	-	26627737	RPE1	viability after 15 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.1594916361671309	[1386]	[397,476]	1	hSpCas9	negative selection	1325232
169237790	169237813	6	-	26627737	RPE1	viability after 18 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.6914385892127088	[520]	[184,271]	4	hSpCas9	negative selection	1407542
169239619	169239642	6	+	26627737	RPE1	viability after 18 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	0.9764685505258671	[472]	[255,245]	6	hSpCas9	negative selection	1407543
169240559	169240582	6	+	26627737	RPE1	viability after 18 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	1.1542376759836097	[1296]	[298,1291]	6	hSpCas9	negative selection	1407544
169241761	169241784	6	-	26627737	RPE1	viability after 18 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.9104861398154638	[628]	[189,456]	5	hSpCas9	negative selection	1407545
169248814	169248837	6	+	26627737	RPE1	viability after 18 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	2.4292661410389664	[110]	[185,134]	9	hSpCas9	negative selection	1407546
169250732	169250755	6	-	26627737	RPE1	viability after 18 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.20098332576896094	[1386]	[364,499]	1	hSpCas9	negative selection	1407547
169237790	169237813	6	-	26627737	HeLa	viability after 8 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	1.4011826949984636	[196]	[215,205,252]	8	hSpCas9	negative selection	1489857
169239619	169239642	6	+	26627737	HeLa	viability after 8 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	-0.07587539108003194	[316]	[155,123,118]	0	hSpCas9	negative selection	1489858
169240559	169240582	6	+	26627737	HeLa	viability after 8 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.45431252393302435	[515]	[283,211,413]	4	hSpCas9	negative selection	1489859
169241761	169241784	6	-	26627737	HeLa	viability after 8 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	-0.9085538800820253	[365]	[76,93,81]	-7	hSpCas9	negative selection	1489860
169248814	169248837	6	+	26627737	HeLa	viability after 8 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.9239228600404338	[367]	[223,545,135]	7	hSpCas9	negative selection	1489861
169250732	169250755	6	-	26627737	HeLa	viability after 8 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.7541073925279536	[681]	[448,433,599]	6	hSpCas9	negative selection	1489862
169237790	169237813	6	-	26627737	HeLa	viability after 12 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	1.493198838918124	[196]	[257,232,196]	8	hSpCas9	negative selection	1572172
169239619	169239642	6	+	26627737	HeLa	viability after 12 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	-0.12962886998783674	[316]	[71,174,104]	-1	hSpCas9	negative selection	1572173
169240559	169240582	6	+	26627737	HeLa	viability after 12 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.4373976779376454	[515]	[172,240,453]	4	hSpCas9	negative selection	1572174
169241761	169241784	6	-	26627737	HeLa	viability after 12 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	-1.1168805585713795	[365]	[112,45,53]	-8	hSpCas9	negative selection	1572175
169248814	169248837	6	+	26627737	HeLa	viability after 12 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.5997345329513143	[367]	[153,269,260]	5	hSpCas9	negative selection	1572176
169250732	169250755	6	-	26627737	HeLa	viability after 12 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	1.100598465746163	[681]	[802,490,536]	7	hSpCas9	negative selection	1572177
169237790	169237813	6	-	26627737	HeLa	viability after 15 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	1.4422148052310502	[196]	[310,154,183]	8	hSpCas9	negative selection	1654487
169239619	169239642	6	+	26627737	HeLa	viability after 15 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	0.13924645210469314	[316]	[116,151,158]	1	hSpCas9	negative selection	1654488
169240559	169240582	6	+	26627737	HeLa	viability after 15 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.2807662650091588	[515]	[144,221,411]	2	hSpCas9	negative selection	1654489
169241761	169241784	6	-	26627737	HeLa	viability after 15 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	-1.763311844413452	[365]	[72,17,39]	-9	hSpCas9	negative selection	1654490
169248814	169248837	6	+	26627737	HeLa	viability after 15 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.44083256596817477	[367]	[148,158,310]	3	hSpCas9	negative selection	1654491
169250732	169250755	6	-	26627737	HeLa	viability after 15 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	1.2308973391636027	[681]	[930,288,737]	8	hSpCas9	negative selection	1654492
169237790	169237813	6	-	26627737	HeLa	viability after 18 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	1.470035225600265	[196]	[213,131,183]	8	hSpCas9	negative selection	1736802
169239619	169239642	6	+	26627737	HeLa	viability after 18 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	0.14137856561079026	[316]	[77,126,158]	1	hSpCas9	negative selection	1736803
169240559	169240582	6	+	26627737	HeLa	viability after 18 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.26278751011888857	[515]	[98,173,411]	2	hSpCas9	negative selection	1736804
169241761	169241784	6	-	26627737	HeLa	viability after 18 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	-1.7349366728063371	[365]	[52,11,39]	-9	hSpCas9	negative selection	1736805
169248814	169248837	6	+	26627737	HeLa	viability after 18 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.4309547977230873	[367]	[100,126,310]	3	hSpCas9	negative selection	1736806
169250732	169250755	6	-	26627737	HeLa	viability after 18 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	1.2582806512202267	[681]	[645,242,737]	8	hSpCas9	negative selection	1736807
169237790	169237813	6	-	26627737	HCT116	viability after 6 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	-0.2866504102053986	[857]	[243,36]	-2	hSpCas9	negative selection	1819117
169239619	169239642	6	+	26627737	HCT116	viability after 6 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	-1.321060279636814	[332]	[38,10]	-6	hSpCas9	negative selection	1819118
169240559	169240582	6	+	26627737	HCT116	viability after 6 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.3916187727308268	[1192]	[421,148]	2	hSpCas9	negative selection	1819119
169241761	169241784	6	-	26627737	HCT116	viability after 6 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.13168783114371924	[433]	[115,51]	0	hSpCas9	negative selection	1819120
169248814	169248837	6	+	26627737	HCT116	viability after 6 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	-0.985370692941936	[1135]	[202,27]	-5	hSpCas9	negative selection	1819121
169250732	169250755	6	-	26627737	HCT116	viability after 6 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	1.061711193169189	[1328]	[254,535]	6	hSpCas9	negative selection	1819122
169237790	169237813	6	-	26627737	HCT116	viability after 8 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.12375633200871256	[379]	[200,258,223]	1	hSpCas9	negative selection	1901432
169239619	169239642	6	+	26627737	HCT116	viability after 8 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	-0.059098700850477776	[280]	[163,203,78]	0	hSpCas9	negative selection	1901433
169240559	169240582	6	+	26627737	HCT116	viability after 8 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.3615522119764769	[473]	[259,378,365]	4	hSpCas9	negative selection	1901434
169241761	169241784	6	-	26627737	HCT116	viability after 8 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.6342953244075056	[148]	[126,184,70]	6	hSpCas9	negative selection	1901435
169248814	169248837	6	+	26627737	HCT116	viability after 8 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.6207492635457192	[219]	[185,251,121]	6	hSpCas9	negative selection	1901436
169250732	169250755	6	-	26627737	HCT116	viability after 8 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.24885448702163004	[706]	[497,396,493]	2	hSpCas9	negative selection	1901437
169237790	169237813	6	-	26627737	HCT116	viability after 9 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.10330435224417245	[857]	[287,212]	0	hSpCas9	negative selection	1983747
169239619	169239642	6	+	26627737	HCT116	viability after 9 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	-0.8417535289170215	[332]	[100,8]	-5	hSpCas9	negative selection	1983748
169240559	169240582	6	+	26627737	HCT116	viability after 9 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	-0.0653248790797909	[1192]	[199,386]	0	hSpCas9	negative selection	1983749
169241761	169241784	6	-	26627737	HCT116	viability after 9 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.3817572411455973	[433]	[317,18]	3	hSpCas9	negative selection	1983750
169248814	169248837	6	+	26627737	HCT116	viability after 9 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	-1.1175181637162663	[1135]	[279,28]	-7	hSpCas9	negative selection	1983751
169250732	169250755	6	-	26627737	HCT116	viability after 9 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	-0.1507517329659972	[1328]	[465,203]	-1	hSpCas9	negative selection	1983752
169237790	169237813	6	-	26627737	HCT116	viability after 12 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.37175120898538955	[379]	[207,397,176]	3	hSpCas9	negative selection	2066062
169239619	169239642	6	+	26627737	HCT116	viability after 12 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	-0.08838768827510585	[280]	[134,219,63]	-1	hSpCas9	negative selection	2066063
169240559	169240582	6	+	26627737	HCT116	viability after 12 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.3626645121727916	[473]	[251,407,308]	3	hSpCas9	negative selection	2066064
169241761	169241784	6	-	26627737	HCT116	viability after 12 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.3644258053998227	[148]	[154,114,27]	3	hSpCas9	negative selection	2066065
169248814	169248837	6	+	26627737	HCT116	viability after 12 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.8483906533605206	[219]	[204,299,121]	7	hSpCas9	negative selection	2066066
169250732	169250755	6	-	26627737	HCT116	viability after 12 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.26345336319590973	[706]	[455,483,397]	2	hSpCas9	negative selection	2066067
169237790	169237813	6	-	26627737	HCT116	viability after 15 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.2553865994621937	[379]	[214,304,255]	2	hSpCas9	negative selection	2148377
169239619	169239642	6	+	26627737	HCT116	viability after 15 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	0.1488251586062606	[280]	[149,185,196]	1	hSpCas9	negative selection	2148378
169240559	169240582	6	+	26627737	HCT116	viability after 15 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.5028931555138658	[473]	[352,393,405]	5	hSpCas9	negative selection	2148379
169241761	169241784	6	-	26627737	HCT116	viability after 15 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	1.04248918812407	[148]	[291,169,81]	8	hSpCas9	negative selection	2148380
169248814	169248837	6	+	26627737	HCT116	viability after 15 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.7184901764529226	[219]	[168,245,203]	6	hSpCas9	negative selection	2148381
169250732	169250755	6	-	26627737	HCT116	viability after 15 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.27514594948064186	[706]	[556,598,327]	2	hSpCas9	negative selection	2148382
169237790	169237813	6	-	26627737	HCT116	viability after 18 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.5156972619350273	[379]	[298,272,212]	4	hSpCas9	negative selection	2230692
169239619	169239642	6	+	26627737	HCT116	viability after 18 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	-0.40337913108375567	[280]	[90,142,69]	-4	hSpCas9	negative selection	2230693
169240559	169240582	6	+	26627737	HCT116	viability after 18 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.4002593819068727	[473]	[327,379,188]	3	hSpCas9	negative selection	2230694
169241761	169241784	6	-	26627737	HCT116	viability after 18 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.26866251298409216	[148]	[32,145,76]	2	hSpCas9	negative selection	2230695
169248814	169248837	6	+	26627737	HCT116	viability after 18 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.6110150700480267	[219]	[178,149,158]	5	hSpCas9	negative selection	2230696
169250732	169250755	6	-	26627737	HCT116	viability after 18 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.3251782006569912	[706]	[468,553,244]	3	hSpCas9	negative selection	2230697
169244323	169244346	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACACACACACACACACACAAGG	THBS2	ENSG00000186340	0.8885735126799061	[159,158]	[51,78]	3	dCas9-VP64	positive selection	2434217
169244323	169244346	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACACACACACACACACACAAGG	THBS2	ENSG00000186340	0.026125821218921985	[69,255]	[35,68]	0	dCas9-VP64	positive selection	2529472
169248470	169248493	6	-	27260157	DLD1	viability	CTTCTACGAGCACCTGCAGGCGG	THBS2	ENSG00000186340	1.27158737561353	[]	[]	9	hSpCas9	negative selection	2574711
169248740	169248763	6	+	27260157	DLD1	viability	ACTTGCCGTCCTGCTTGAGCTGG	THBS2	ENSG00000186340	0.665438988524726	[]	[]	8	hSpCas9	negative selection	2575433
169248855	169248878	6	+	27260157	DLD1	viability	GAAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	1.06328249828799	[]	[]	9	hSpCas9	negative selection	2582375
169248500	169248523	6	-	27260157	DLD1	viability	CCTCATAGACAGCTTCGCTCTGG	THBS2	ENSG00000186340	0.356607729067253	[]	[]	4	hSpCas9	negative selection	2583141
169248904	169248927	6	-	27260157	DLD1	viability	AACATCAACCGCAAGACCATTGG	THBS2	ENSG00000186340	1.15833873171953	[]	[]	9	hSpCas9	negative selection	2583541
169248624	169248647	6	+	27260157	DLD1	viability	CCGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.0784639623849131	[]	[]	3	hSpCas9	negative selection	2606578
169248830	169248853	6	-	27260157	DLD1	viability	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	-0.743572803876598	[]	[]	-5	hSpCas9	negative selection	2608736
169248780	169248803	6	+	27260157	DLD1	viability	CTCCTTCTGCCGCATGATCTTGG	THBS2	ENSG00000186340	1.14736649971787	[]	[]	9	hSpCas9	negative selection	2609332
169248670	169248693	6	-	27260157	DLD1	viability	CAGTTCGAGATCGTCTCCAACGG	THBS2	ENSG00000186340	0.245812097824675	[]	[]	4	hSpCas9	negative selection	2611647
169248885	169248908	6	-	27260157	DLD1	viability	TTGGCGCCAAGCAGTTCCGCGGG	THBS2	ENSG00000186340	-0.0226867899559142	[]	[]	0	hSpCas9	negative selection	2616379
169248811	169248834	6	+	27260157	DLD1	viability	CTGAGGTCATCTGCGTTCACCGG	THBS2	ENSG00000186340	0.71304799696795	[]	[]	8	hSpCas9	negative selection	2618875
169248525	169248548	6	+	27260157	DLD1	viability	GCAGCCCACGTGCAAGCTGTAGG	THBS2	ENSG00000186340	0.52748240244005	[]	[]	8	hSpCas9	negative selection	2618993
169248944	169248967	6	+	27260157	DLD1	viability	CGAAGGTCGTGTCTTTGTCCTGG	THBS2	ENSG00000186340	-0.585635332039659	[]	[]	-5	hSpCas9	negative selection	2619046
169248500	169248523	6	+	27260157	DLD1	viability	CCAGAGCGAAGCTGTCTATGAGG	THBS2	ENSG00000186340	0.392040174887072	[]	[]	4	hSpCas9	negative selection	2620227
169248839	169248862	6	+	27260157	DLD1	viability	TGTAGTCAAAGCGCACGAAGCGG	THBS2	ENSG00000186340	-0.528568296182718	[]	[]	-4	hSpCas9	negative selection	2622028
169248617	169248640	6	-	27260157	DLD1	viability	GATTGACGGCACCCGGCATGTGG	THBS2	ENSG00000186340	0.384302262250411	[]	[]	4	hSpCas9	negative selection	2623676
169248789	169248812	6	-	27260157	DLD1	viability	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	-0.831073521436461	[]	[]	-6	hSpCas9	negative selection	2641367
169248677	169248700	6	+	27260157	DLD1	viability	AGACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.424690680416834	[]	[]	7	hSpCas9	negative selection	2641577
169248879	169248902	6	+	27260157	DLD1	viability	GTCGGGCCCGCGGAACTGCTTGG	THBS2	ENSG00000186340	1.46629503820577	[]	[]	9	hSpCas9	negative selection	2646094
169248579	169248602	6	-	27260157	DLD1	viability	TCGGCCTGGCTGACTCGCAGTGG	THBS2	ENSG00000186340	0.853732543220604	[]	[]	9	hSpCas9	negative selection	2647928
169248470	169248493	6	-	27260157	HT1080	viability	CTTCTACGAGCACCTGCAGGCGG	THBS2	ENSG00000186340	0.513787919736907	[]	[]	4	hSpCas9	negative selection	2650841
169248740	169248763	6	+	27260157	HT1080	viability	ACTTGCCGTCCTGCTTGAGCTGG	THBS2	ENSG00000186340	0.7207157181173	[]	[]	6	hSpCas9	negative selection	2651563
169248855	169248878	6	+	27260157	HT1080	viability	GAAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.545508700927461	[]	[]	5	hSpCas9	negative selection	2658505
169248500	169248523	6	-	27260157	HT1080	viability	CCTCATAGACAGCTTCGCTCTGG	THBS2	ENSG00000186340	-0.317789385476458	[]	[]	-7	hSpCas9	negative selection	2659271
169248904	169248927	6	-	27260157	HT1080	viability	AACATCAACCGCAAGACCATTGG	THBS2	ENSG00000186340	0.640443227939858	[]	[]	5	hSpCas9	negative selection	2659671
169248624	169248647	6	+	27260157	HT1080	viability	CCGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.827103679932884	[]	[]	7	hSpCas9	negative selection	2682708
169248830	169248853	6	-	27260157	HT1080	viability	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	-0.625541783563581	[]	[]	-8	hSpCas9	negative selection	2684866
169248780	169248803	6	+	27260157	HT1080	viability	CTCCTTCTGCCGCATGATCTTGG	THBS2	ENSG00000186340	-0.568516853899447	[]	[]	-7	hSpCas9	negative selection	2685462
169248670	169248693	6	-	27260157	HT1080	viability	CAGTTCGAGATCGTCTCCAACGG	THBS2	ENSG00000186340	0.443570616663829	[]	[]	4	hSpCas9	negative selection	2687777
169248885	169248908	6	-	27260157	HT1080	viability	TTGGCGCCAAGCAGTTCCGCGGG	THBS2	ENSG00000186340	-0.61691265064139	[]	[]	-8	hSpCas9	negative selection	2692509
169248811	169248834	6	+	27260157	HT1080	viability	CTGAGGTCATCTGCGTTCACCGG	THBS2	ENSG00000186340	0.245644412704522	[]	[]	2	hSpCas9	negative selection	2695005
169248525	169248548	6	+	27260157	HT1080	viability	GCAGCCCACGTGCAAGCTGTAGG	THBS2	ENSG00000186340	0.371288115662082	[]	[]	3	hSpCas9	negative selection	2695123
169248944	169248967	6	+	27260157	HT1080	viability	CGAAGGTCGTGTCTTTGTCCTGG	THBS2	ENSG00000186340	-0.602469065825496	[]	[]	-7	hSpCas9	negative selection	2695176
169248500	169248523	6	+	27260157	HT1080	viability	CCAGAGCGAAGCTGTCTATGAGG	THBS2	ENSG00000186340	-0.457184561069386	[]	[]	-7	hSpCas9	negative selection	2696357
169248839	169248862	6	+	27260157	HT1080	viability	TGTAGTCAAAGCGCACGAAGCGG	THBS2	ENSG00000186340	-0.637356950011465	[]	[]	-8	hSpCas9	negative selection	2698158
169248617	169248640	6	-	27260157	HT1080	viability	GATTGACGGCACCCGGCATGTGG	THBS2	ENSG00000186340	0.368038901707389	[]	[]	3	hSpCas9	negative selection	2699806
169248789	169248812	6	-	27260157	HT1080	viability	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	0.395840789617207	[]	[]	3	hSpCas9	negative selection	2717497
169248677	169248700	6	+	27260157	HT1080	viability	AGACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.945438059836979	[]	[]	7	hSpCas9	negative selection	2717707
169248879	169248902	6	+	27260157	HT1080	viability	GTCGGGCCCGCGGAACTGCTTGG	THBS2	ENSG00000186340	0.724552555621177	[]	[]	6	hSpCas9	negative selection	2722224
169248579	169248602	6	-	27260157	HT1080	viability	TCGGCCTGGCTGACTCGCAGTGG	THBS2	ENSG00000186340	0.19913872882465	[]	[]	2	hSpCas9	negative selection	2724058
169248470	169248493	6	-	27260157	MKN45	viability	CTTCTACGAGCACCTGCAGGCGG	THBS2	ENSG00000186340	1.14963297884996	[]	[]	8	hSpCas9	negative selection	2726971
169248740	169248763	6	+	27260157	MKN45	viability	ACTTGCCGTCCTGCTTGAGCTGG	THBS2	ENSG00000186340	0.965778441881153	[]	[]	8	hSpCas9	negative selection	2727693
169248855	169248878	6	+	27260157	MKN45	viability	GAAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	1.04369959782167	[]	[]	8	hSpCas9	negative selection	2734635
169248500	169248523	6	-	27260157	MKN45	viability	CCTCATAGACAGCTTCGCTCTGG	THBS2	ENSG00000186340	-1.20261370120041	[]	[]	-8	hSpCas9	negative selection	2735401
169248904	169248927	6	-	27260157	MKN45	viability	AACATCAACCGCAAGACCATTGG	THBS2	ENSG00000186340	1.3044082302986	[]	[]	9	hSpCas9	negative selection	2735801
169248624	169248647	6	+	27260157	MKN45	viability	CCGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	-0.243837053992094	[]	[]	-1	hSpCas9	negative selection	2758838
169248830	169248853	6	-	27260157	MKN45	viability	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	0.0413559427265984	[]	[]	0	hSpCas9	negative selection	2760996
169248780	169248803	6	+	27260157	MKN45	viability	CTCCTTCTGCCGCATGATCTTGG	THBS2	ENSG00000186340	-0.268897339898155	[]	[]	-1	hSpCas9	negative selection	2761592
169248670	169248693	6	-	27260157	MKN45	viability	CAGTTCGAGATCGTCTCCAACGG	THBS2	ENSG00000186340	0.749222011758265	[]	[]	7	hSpCas9	negative selection	2763907
169248885	169248908	6	-	27260157	MKN45	viability	TTGGCGCCAAGCAGTTCCGCGGG	THBS2	ENSG00000186340	-0.161819753373491	[]	[]	0	hSpCas9	negative selection	2768639
169248811	169248834	6	+	27260157	MKN45	viability	CTGAGGTCATCTGCGTTCACCGG	THBS2	ENSG00000186340	0.900410848314859	[]	[]	8	hSpCas9	negative selection	2771135
169248525	169248548	6	+	27260157	MKN45	viability	GCAGCCCACGTGCAAGCTGTAGG	THBS2	ENSG00000186340	0.389039889351895	[]	[]	6	hSpCas9	negative selection	2771253
169248944	169248967	6	+	27260157	MKN45	viability	CGAAGGTCGTGTCTTTGTCCTGG	THBS2	ENSG00000186340	-0.158037977552776	[]	[]	0	hSpCas9	negative selection	2771306
169248500	169248523	6	+	27260157	MKN45	viability	CCAGAGCGAAGCTGTCTATGAGG	THBS2	ENSG00000186340	-0.0357547033825926	[]	[]	0	hSpCas9	negative selection	2772487
169248839	169248862	6	+	27260157	MKN45	viability	TGTAGTCAAAGCGCACGAAGCGG	THBS2	ENSG00000186340	-0.0539716077158407	[]	[]	0	hSpCas9	negative selection	2774288
169248617	169248640	6	-	27260157	MKN45	viability	GATTGACGGCACCCGGCATGTGG	THBS2	ENSG00000186340	0.942645008254803	[]	[]	8	hSpCas9	negative selection	2775936
169248789	169248812	6	-	27260157	MKN45	viability	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	0.106905981954596	[]	[]	4	hSpCas9	negative selection	2793627
169248677	169248700	6	+	27260157	MKN45	viability	AGACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	1.52252056220803	[]	[]	9	hSpCas9	negative selection	2793837
169248879	169248902	6	+	27260157	MKN45	viability	GTCGGGCCCGCGGAACTGCTTGG	THBS2	ENSG00000186340	0.65339310155446	[]	[]	7	hSpCas9	negative selection	2798354
169248579	169248602	6	-	27260157	MKN45	viability	TCGGCCTGGCTGACTCGCAGTGG	THBS2	ENSG00000186340	0.65870001840471	[]	[]	7	hSpCas9	negative selection	2800188
169248470	169248493	6	-	27260157	RKO	viability	CTTCTACGAGCACCTGCAGGCGG	THBS2	ENSG00000186340	0.523503882147987	[]	[]	2	hSpCas9	negative selection	2803101
169248740	169248763	6	+	27260157	RKO	viability	ACTTGCCGTCCTGCTTGAGCTGG	THBS2	ENSG00000186340	0.164185597865643	[]	[]	0	hSpCas9	negative selection	2803823
169248855	169248878	6	+	27260157	RKO	viability	GAAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.670847069226514	[]	[]	7	hSpCas9	negative selection	2810765
169248500	169248523	6	-	27260157	RKO	viability	CCTCATAGACAGCTTCGCTCTGG	THBS2	ENSG00000186340	-0.565544665465261	[]	[]	-7	hSpCas9	negative selection	2811531
169248904	169248927	6	-	27260157	RKO	viability	AACATCAACCGCAAGACCATTGG	THBS2	ENSG00000186340	0.845187670858863	[]	[]	8	hSpCas9	negative selection	2811931
169248624	169248647	6	+	27260157	RKO	viability	CCGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.264215956808515	[]	[]	1	hSpCas9	negative selection	2834968
169248830	169248853	6	-	27260157	RKO	viability	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	-0.255241629839586	[]	[]	-1	hSpCas9	negative selection	2837126
169248780	169248803	6	+	27260157	RKO	viability	CTCCTTCTGCCGCATGATCTTGG	THBS2	ENSG00000186340	0.247685587282174	[]	[]	1	hSpCas9	negative selection	2837722
169248670	169248693	6	-	27260157	RKO	viability	CAGTTCGAGATCGTCTCCAACGG	THBS2	ENSG00000186340	0.631204014351575	[]	[]	3	hSpCas9	negative selection	2840037
169248885	169248908	6	-	27260157	RKO	viability	TTGGCGCCAAGCAGTTCCGCGGG	THBS2	ENSG00000186340	-0.604853835805347	[]	[]	-7	hSpCas9	negative selection	2844769
169248811	169248834	6	+	27260157	RKO	viability	CTGAGGTCATCTGCGTTCACCGG	THBS2	ENSG00000186340	0.637539943039271	[]	[]	3	hSpCas9	negative selection	2847265
169248525	169248548	6	+	27260157	RKO	viability	GCAGCCCACGTGCAAGCTGTAGG	THBS2	ENSG00000186340	0.295979848431731	[]	[]	1	hSpCas9	negative selection	2847383
169248944	169248967	6	+	27260157	RKO	viability	CGAAGGTCGTGTCTTTGTCCTGG	THBS2	ENSG00000186340	-0.326854620089207	[]	[]	-6	hSpCas9	negative selection	2847436
169248500	169248523	6	+	27260157	RKO	viability	CCAGAGCGAAGCTGTCTATGAGG	THBS2	ENSG00000186340	0.076234022226452	[]	[]	0	hSpCas9	negative selection	2848617
169248839	169248862	6	+	27260157	RKO	viability	TGTAGTCAAAGCGCACGAAGCGG	THBS2	ENSG00000186340	-0.176411873185688	[]	[]	-1	hSpCas9	negative selection	2850418
169248617	169248640	6	-	27260157	RKO	viability	GATTGACGGCACCCGGCATGTGG	THBS2	ENSG00000186340	0.280170447343301	[]	[]	1	hSpCas9	negative selection	2852066
169248789	169248812	6	-	27260157	RKO	viability	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	0.313171474589583	[]	[]	1	hSpCas9	negative selection	2869757
169248677	169248700	6	+	27260157	RKO	viability	AGACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.98592174909408	[]	[]	9	hSpCas9	negative selection	2869967
169248879	169248902	6	+	27260157	RKO	viability	GTCGGGCCCGCGGAACTGCTTGG	THBS2	ENSG00000186340	0.588590173625124	[]	[]	3	hSpCas9	negative selection	2874484
169248579	169248602	6	-	27260157	RKO	viability	TCGGCCTGGCTGACTCGCAGTGG	THBS2	ENSG00000186340	0.745229801224661	[]	[]	8	hSpCas9	negative selection	2876318
169248470	169248493	6	-	27260157	SF268	viability	CTTCTACGAGCACCTGCAGGCGG	THBS2	ENSG00000186340	0.258280209775125	[]	[]	4	hSpCas9	negative selection	2879231
169248740	169248763	6	+	27260157	SF268	viability	ACTTGCCGTCCTGCTTGAGCTGG	THBS2	ENSG00000186340	0.800887995854872	[]	[]	8	hSpCas9	negative selection	2879953
169248855	169248878	6	+	27260157	SF268	viability	GAAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.89954453405512	[]	[]	9	hSpCas9	negative selection	2886895
169248500	169248523	6	-	27260157	SF268	viability	CCTCATAGACAGCTTCGCTCTGG	THBS2	ENSG00000186340	0.0344360895875221	[]	[]	0	hSpCas9	negative selection	2887661
169248904	169248927	6	-	27260157	SF268	viability	AACATCAACCGCAAGACCATTGG	THBS2	ENSG00000186340	1.29239668029228	[]	[]	9	hSpCas9	negative selection	2888061
169248624	169248647	6	+	27260157	SF268	viability	CCGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.603482385898217	[]	[]	8	hSpCas9	negative selection	2911098
169248830	169248853	6	-	27260157	SF268	viability	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	-0.977803649733206	[]	[]	-7	hSpCas9	negative selection	2913256
169248780	169248803	6	+	27260157	SF268	viability	CTCCTTCTGCCGCATGATCTTGG	THBS2	ENSG00000186340	0.286629679199154	[]	[]	4	hSpCas9	negative selection	2913852
169248670	169248693	6	-	27260157	SF268	viability	CAGTTCGAGATCGTCTCCAACGG	THBS2	ENSG00000186340	1.01999152847156	[]	[]	9	hSpCas9	negative selection	2916167
169248885	169248908	6	-	27260157	SF268	viability	TTGGCGCCAAGCAGTTCCGCGGG	THBS2	ENSG00000186340	-0.514365374069025	[]	[]	-4	hSpCas9	negative selection	2920899
169248811	169248834	6	+	27260157	SF268	viability	CTGAGGTCATCTGCGTTCACCGG	THBS2	ENSG00000186340	0.441878124298752	[]	[]	7	hSpCas9	negative selection	2923395
169248525	169248548	6	+	27260157	SF268	viability	GCAGCCCACGTGCAAGCTGTAGG	THBS2	ENSG00000186340	0.608322958734391	[]	[]	8	hSpCas9	negative selection	2923513
169248944	169248967	6	+	27260157	SF268	viability	CGAAGGTCGTGTCTTTGTCCTGG	THBS2	ENSG00000186340	-0.145429115125374	[]	[]	-1	hSpCas9	negative selection	2923566
169248500	169248523	6	+	27260157	SF268	viability	CCAGAGCGAAGCTGTCTATGAGG	THBS2	ENSG00000186340	0.902796511131221	[]	[]	9	hSpCas9	negative selection	2924747
169248839	169248862	6	+	27260157	SF268	viability	TGTAGTCAAAGCGCACGAAGCGG	THBS2	ENSG00000186340	0.364023658345933	[]	[]	4	hSpCas9	negative selection	2926548
169248617	169248640	6	-	27260157	SF268	viability	GATTGACGGCACCCGGCATGTGG	THBS2	ENSG00000186340	0.476824282028204	[]	[]	7	hSpCas9	negative selection	2928196
169248789	169248812	6	-	27260157	SF268	viability	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	0.366174275065313	[]	[]	4	hSpCas9	negative selection	2945887
169248677	169248700	6	+	27260157	SF268	viability	AGACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	1.04367875527931	[]	[]	9	hSpCas9	negative selection	2946097
169248879	169248902	6	+	27260157	SF268	viability	GTCGGGCCCGCGGAACTGCTTGG	THBS2	ENSG00000186340	1.00197492299728	[]	[]	9	hSpCas9	negative selection	2950614
169248579	169248602	6	-	27260157	SF268	viability	TCGGCCTGGCTGACTCGCAGTGG	THBS2	ENSG00000186340	1.03720717342196	[]	[]	9	hSpCas9	negative selection	2952448
169248886	169248909	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTGGCGCCAAGCAGTTCCGCGG	THBS2	ENSG00000186340	0.38464949562634576	[3,4]	[3,5]	7	hSpCas9	positive selection	3026620
169234720	169234743	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACCCCTCACTCACCCACGGGG	THBS2	ENSG00000186340	0.16517682762921598	[5,4]	[4,5]	3	hSpCas9	positive selection	3026621
169248789	169248812	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	0.17848747940368184	[3,2]	[1,3]	4	hSpCas9	positive selection	3026622
169248830	169248853	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	-0.05545238830091899	[3,3]	[4,0]	-1	hSpCas9	positive selection	3026623
169248886	169248909	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTGGCGCCAAGCAGTTCCGCGG	THBS2	ENSG00000186340	-0.3336736253169192	[3,3]	[3,0]	-5	hSpCas9	positive selection	3094478
169234720	169234743	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACCCCTCACTCACCCACGGGG	THBS2	ENSG00000186340	0.19768275169110977	[5,5]	[5,3]	3	hSpCas9	positive selection	3094479
169248789	169248812	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	-0.11669890318015883	[3,3]	[3,1]	-2	hSpCas9	positive selection	3094480
169248830	169248853	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	0.12418858651233218	[3,3]	[2,2]	2	hSpCas9	positive selection	3094481
169246205	169246228		-	24336571	A375	resistance to PLX after 7 days	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.33514847775848894	[12,9]	[7,9]	-8	hSpCas9	positive selection	3150129
169240446	169240469		+	24336571	A375	resistance to PLX after 7 days	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	-0.032350707854623184	[16,15]	[15,16]	-1	hSpCas9	positive selection	3150130
169240451	169240474		-	24336571	A375	resistance to PLX after 7 days	CTGCACCACGTGTACCTGCAAGG	THBS2	ENSG00000186340	0.14248975385359586	[31,26]	[32,30]	4	hSpCas9	positive selection	3150131
169246205	169246228		-	24336571	A375	resistance to PLX after 14 days	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.3212273369247522	[12,7]	[2,3]	-4	hSpCas9	positive selection	3207922
169240446	169240469		+	24336571	A375	resistance to PLX after 14 days	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	-0.32099847890635275	[16,19]	[6,5]	-4	hSpCas9	positive selection	3207923
169240451	169240474		-	24336571	A375	resistance to PLX after 14 days	CTGCACCACGTGTACCTGCAAGG	THBS2	ENSG00000186340	-0.2915163621147179	[36,25]	[13,9]	-3	hSpCas9	positive selection	3207924
169246205	169246228		-	24336571	A375	viability after 7 days	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.3354840623949105	[8]	[12,9]	5	hSpCas9	negative selection	3265715
169240446	169240469		+	24336571	A375	viability after 7 days	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.4996747885029086	[11]	[16,15]	7	hSpCas9	negative selection	3265716
169240451	169240474		-	24336571	A375	viability after 7 days	CTGCACCACGTGTACCTGCAAGG	THBS2	ENSG00000186340	0.7421608035344277	[17]	[31,26]	9	hSpCas9	negative selection	3265717
169246205	169246228		-	24336571	A375	viability after 14 days	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.2267507312959961	[8]	[12,7]	3	hSpCas9	negative selection	3323508
169240446	169240469		+	24336571	A375	viability after 14 days	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.6528969165916376	[11]	[16,19]	8	hSpCas9	negative selection	3323509
169240451	169240474		-	24336571	A375	viability after 14 days	CTGCACCACGTGTACCTGCAAGG	THBS2	ENSG00000186340	0.8724280071549207	[17]	[36,25]	9	hSpCas9	negative selection	3323510
169240569	169240592	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	1.5568864933047428	[207,207]	[3,3]	6	hSpCas9	positive selection	3397054
169246205	169246228	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	2.4499712893882313	[27,27]	[0,0]	8	hSpCas9	positive selection	3397055
169246239	169246262	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	-0.21027933863716222	[176,176]	[0,0]	-1	hSpCas9	positive selection	3397056
169248886	169248909	6	-	26780180	HT29	viability (Avana library 4 designs)	ATTGGCGCCAAGCAGTTCCGCGG	THBS2	ENSG00000186340	-0.113984902538502	[]	[]	-2	hSpCas9	negative selection	3465359
169234719	169234742	6	+	26780180	HT29	viability (Avana library 4 designs)	CTACCCCTCACTCACCCACGGGG	THBS2	ENSG00000186340	0.0996934635865858	[]	[]	0	hSpCas9	negative selection	3465360
169248789	169248812	6	-	26780180	HT29	viability (Avana library 4 designs)	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	0.603704644874193	[]	[]	2	hSpCas9	negative selection	3465361
169248830	169248853	6	-	26780180	HT29	viability (Avana library 4 designs)	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	1.61381542769087	[]	[]	6	hSpCas9	negative selection	3465362
169234719	169234742	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCCCTCACTCACCCACGGGG	THBS2	ENSG00000186340	1.56981522354209	[]	[]	2	hSpCas9	negative selection	3568515
169248830	169248853	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	-3.44771812875637	[]	[]	-4	hSpCas9	negative selection	3568516
169248789	169248812	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	-1.5848091304909	[]	[]	-2	hSpCas9	negative selection	3568517
169248886	169248909	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATTGGCGCCAAGCAGTTCCGCGG	THBS2	ENSG00000186340	5.25374600648489	[]	[]	8	hSpCas9	negative selection	3568518
169248815	169248838	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCATCTGCGTTCACCGGTGGG	THBS2	ENSG00000186340	1.30205685470647	[]	[]	1	hSpCas9	negative selection	3568519
169248689	169248712	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	4.93210434061374	[]	[]	8	hSpCas9	negative selection	3568520
169234719	169234742	6	+	26780180	A375	viability (Avana lentiGuide)	CTACCCCTCACTCACCCACGGGG	THBS2	ENSG00000186340	4.06798051364528	[]	[]	4	hSpCas9	negative selection	3677174
169248830	169248853	6	-	26780180	A375	viability (Avana lentiGuide)	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	5.17939326793787	[]	[]	4	hSpCas9	negative selection	3677175
169248789	169248812	6	-	26780180	A375	viability (Avana lentiGuide)	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	8.33100438428601	[]	[]	6	hSpCas9	negative selection	3677176
169248886	169248909	6	-	26780180	A375	viability (Avana lentiGuide)	ATTGGCGCCAAGCAGTTCCGCGG	THBS2	ENSG00000186340	-1.66660337516937	[]	[]	-3	hSpCas9	negative selection	3677177
169248815	169248838	6	+	26780180	A375	viability (Avana lentiGuide)	GGTCATCTGCGTTCACCGGTGGG	THBS2	ENSG00000186340	2.61539305824769	[]	[]	2	hSpCas9	negative selection	3677178
169248689	169248712	6	+	26780180	A375	viability (Avana lentiGuide)	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	7.77558344012559	[]	[]	6	hSpCas9	negative selection	3677179
169234719	169234742	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCCCTCACTCACCCACGGGG	THBS2	ENSG00000186340	0.08227859975750723	[5]	[5,5]	2	hSpCas9	positive selection	3785781
169248830	169248853	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	-0.3664345203740551	[4]	[2,2]	-5	hSpCas9	positive selection	3785782
169248789	169248812	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	-0.40473251938357824	[5]	[4,2]	-5	hSpCas9	positive selection	3785783
169248886	169248909	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTGGCGCCAAGCAGTTCCGCGG	THBS2	ENSG00000186340	0.3452796328155458	[5]	[7,6]	9	hSpCas9	positive selection	3785784
169248815	169248838	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCATCTGCGTTCACCGGTGGG	THBS2	ENSG00000186340	0.1735250858636658	[3]	[4,3]	5	hSpCas9	positive selection	3785785
169248689	169248712	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	0.33019024766919347	[4]	[5,5]	8	hSpCas9	positive selection	3785786
169234719	169234742	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCCCTCACTCACCCACGGGG	THBS2	ENSG00000186340	0.10620621522792723	[7]	[6,6]	2	hSpCas9	positive selection	3894388
169248830	169248853	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCTTTGACTACATCCCACCGG	THBS2	ENSG00000186340	-0.24328702248537917	[5]	[3,2]	-3	hSpCas9	positive selection	3894389
169248789	169248812	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAGATCACCAAGATCATGCGG	THBS2	ENSG00000186340	-0.3613873466741966	[4]	[0,5]	-5	hSpCas9	positive selection	3894390
169248886	169248909	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTGGCGCCAAGCAGTTCCGCGG	THBS2	ENSG00000186340	0.2504845761252436	[5]	[5,6]	6	hSpCas9	positive selection	3894391
169248815	169248838	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCATCTGCGTTCACCGGTGGG	THBS2	ENSG00000186340	0.2187634177215888	[5]	[5,4]	5	hSpCas9	positive selection	3894392
169248689	169248712	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	-0.06018840994731328	[3]	[2,3]	-1	hSpCas9	positive selection	3894393
169246205	169246228	6	-	26780180	A375	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.403540939948517	[]	[]	1	hSpCas9	negative selection	4003739
169246239	169246262	6	-	26780180	A375	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.287762556244982	[]	[]	0	hSpCas9	negative selection	4003740
169240446	169240469	6	+	26780180	A375	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.559083704839587	[]	[]	1	hSpCas9	negative selection	4003741
169240569	169240592	6	-	26780180	A375	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.993793902109294	[]	[]	4	hSpCas9	negative selection	4003742
169239629	169239652	6	-	26780180	A375	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.733648982351858	[]	[]	2	hSpCas9	negative selection	4003743
169239615	169239638	6	+	26780180	A375	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	1.13708282370649	[]	[]	6	hSpCas9	negative selection	4003744
169246205	169246228	6	-	26780180	HT29	viability (GeCKOv2 library)	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.724149643191271	[]	[]	2	hSpCas9	negative selection	4111705
169246239	169246262	6	-	26780180	HT29	viability (GeCKOv2 library)	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	-0.755844293616163	[]	[]	-9	hSpCas9	negative selection	4111706
169240446	169240469	6	+	26780180	HT29	viability (GeCKOv2 library)	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.365547426759251	[]	[]	1	hSpCas9	negative selection	4111707
169240569	169240592	6	-	26780180	HT29	viability (GeCKOv2 library)	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	1.24198519409461	[]	[]	6	hSpCas9	negative selection	4111708
169239629	169239652	6	-	26780180	HT29	viability (GeCKOv2 library)	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.148184150949691	[]	[]	0	hSpCas9	negative selection	4111709
169239615	169239638	6	+	26780180	HT29	viability (GeCKOv2 library)	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.846450005973492	[]	[]	3	hSpCas9	negative selection	4111710
169246205	169246228	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.13660533150082063	[3]	[2,1]	-3	hSpCas9	positive selection	4176508
169240446	169240469	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.2451230034335834	[3]	[3,2]	6	hSpCas9	positive selection	4176509
169240451	169240474	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGCACCACGTGTACCTGCAAGG	THBS2	ENSG00000186340	0.10341794796945647	[4]	[2,3]	2	hSpCas9	positive selection	4176510
169246205	169246228	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.08044364271162913	[2]	[1,1,1,0]	0	hSpCas9	positive selection	4240530
169240446	169240469	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	-0.13954137471930964	[4]	[2,0,2,0]	-2	hSpCas9	positive selection	4240531
169240451	169240474	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGCACCACGTGTACCTGCAAGG	THBS2	ENSG00000186340	1.2236288839648004	[4]	[3,3,5,4]	8	hSpCas9	positive selection	4240532
169240446	169240469	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.2994493885500152	[4]	[4,3]	6	hSpCas9	positive selection	4302946
169239629	169239652	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.08585920237368136	[2]	[3,1]	1	hSpCas9	positive selection	4302947
169239615	169239638	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.276881333413277	[1]	[2,0]	5	hSpCas9	positive selection	4302948
169240569	169240592	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.03256183017685138	[3]	[3,1]	0	hSpCas9	positive selection	4367200
169246205	169246228	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.44058311860085486	[1]	[1,0]	8	hSpCas9	positive selection	4367201
169246239	169246262	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.41969498870758143	[2]	[3,2]	8	hSpCas9	positive selection	4367202
169237331	169237353	6	-	27760321	OCIAML3	viability	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.3792873983106812	[284,239]	[173,385]	4	hSpCas9	negative selection	4446747
169241887	169241909	6	-	27760321	OCIAML3	viability	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.5468446938054312	[671,540]	[603,799]	6	hSpCas9	negative selection	4446748
169248625	169248647	6	+	27760321	OCIAML3	viability	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.258238921560571	[534,526]	[507,484]	3	hSpCas9	negative selection	4446749
169248678	169248700	6	+	27760321	OCIAML3	viability	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.9203221238129553	[612,538]	[760,967]	9	hSpCas9	negative selection	4446750
169248856	169248878	6	+	27760321	OCIAML3	viability	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.4674362446391669	[886,711]	[889,819]	5	hSpCas9	negative selection	4446751
169237331	169237353	6	-	27760321	OCIAML2	viability	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.8309979812867377	[284,239]	[305,468]	9	hSpCas9	negative selection	4530210
169241887	169241909	6	-	27760321	OCIAML2	viability	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.5619502874613316	[671,540]	[639,825]	7	hSpCas9	negative selection	4530211
169248625	169248647	6	+	27760321	OCIAML2	viability	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.12153647094042791	[534,526]	[386,575]	1	hSpCas9	negative selection	4530212
169248678	169248700	6	+	27760321	OCIAML2	viability	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.5094802709348745	[612,538]	[620,715]	7	hSpCas9	negative selection	4530213
169248856	169248878	6	+	27760321	OCIAML2	viability	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.29526375918905434	[886,711]	[603,1032]	4	hSpCas9	negative selection	4530214
169237331	169237353	6	-	27760321	MV411	viability	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.3979197795889327	[284,239]	[208,254]	3	hSpCas9	negative selection	4613673
169241887	169241909	6	-	27760321	MV411	viability	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.5173590901379436	[671,540]	[647,451]	4	hSpCas9	negative selection	4613674
169248625	169248647	6	+	27760321	MV411	viability	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.06542035854853545	[534,526]	[174,656]	0	hSpCas9	negative selection	4613675
169248678	169248700	6	+	27760321	MV411	viability	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	1.2969608693315569	[612,538]	[1047,757]	8	hSpCas9	negative selection	4613676
169248856	169248878	6	+	27760321	MV411	viability	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.973313694179327	[886,711]	[1196,778]	7	hSpCas9	negative selection	4613677
169237331	169237353	6	-	27760321	HL60	viability	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.320170463678578	[284,239]	[256,276]	4	hSpCas9	negative selection	4697136
169241887	169241909	6	-	27760321	HL60	viability	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.05826336020348044	[671,540]	[478,548]	0	hSpCas9	negative selection	4697137
169248625	169248647	6	+	27760321	HL60	viability	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.47680954685660376	[534,526]	[646,560]	6	hSpCas9	negative selection	4697138
169248678	169248700	6	+	27760321	HL60	viability	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	1.0614921680649034	[612,538]	[915,1047]	9	hSpCas9	negative selection	4697139
169248856	169248878	6	+	27760321	HL60	viability	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.7840158869995077	[886,711]	[990,1252]	8	hSpCas9	negative selection	4697140
169237331	169237353	6	-	27760321	HT1080	viability	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	-0.08437075298015029	[239,186]	[31,132]	0	hSpCas9	negative selection	4780599
169241887	169241909	6	-	27760321	HT1080	viability	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.17772394003576375	[540,421]	[78,367]	0	hSpCas9	negative selection	4780600
169248625	169248647	6	+	27760321	HT1080	viability	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	-0.6858909189693556	[526,410]	[118,112]	-3	hSpCas9	negative selection	4780601
169248678	169248700	6	+	27760321	HT1080	viability	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	1.1020274620809656	[538,420]	[525,283]	6	hSpCas9	negative selection	4780602
169248856	169248878	6	+	27760321	HT1080	viability	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	1.1858581579659737	[711,555]	[892,225]	6	hSpCas9	negative selection	4780603
169237331	169237353	6	-	27760321	HT29	viability after 7 days	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	-0.2784911617798512	[239,186]	[172,209,285]	-4	hSpCas9	negative selection	4864062
169241887	169241909	6	-	27760321	HT29	viability after 7 days	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.3731028635438861	[540,421]	[1294,840,352]	6	hSpCas9	negative selection	4864063
169248625	169248647	6	+	27760321	HT29	viability after 7 days	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	-0.24960310413669806	[526,410]	[581,522,428]	-4	hSpCas9	negative selection	4864064
169248678	169248700	6	+	27760321	HT29	viability after 7 days	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.6692802227318347	[538,420]	[707,1245,950]	8	hSpCas9	negative selection	4864065
169248856	169248878	6	+	27760321	HT29	viability after 7 days	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.5394904324759204	[711,555]	[1651,1025,948]	7	hSpCas9	negative selection	4864066
169237331	169237353	6	-	27760321	HT29	viability after 25 days	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	-0.11335270257137853	[239,186]	[151,198,341]	-1	hSpCas9	negative selection	4947525
169241887	169241909	6	-	27760321	HT29	viability after 25 days	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.6510154351922758	[540,421]	[953,1026,573]	7	hSpCas9	negative selection	4947526
169248625	169248647	6	+	27760321	HT29	viability after 25 days	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.34849736786395974	[526,410]	[527,723,817]	3	hSpCas9	negative selection	4947527
169248678	169248700	6	+	27760321	HT29	viability after 25 days	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.8912068113414194	[538,420]	[1060,987,996]	9	hSpCas9	negative selection	4947528
169248856	169248878	6	+	27760321	HT29	viability after 25 days	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.4309203883030772	[711,555]	[919,901,1125]	5	hSpCas9	negative selection	4947529
169237331	169237353	6	-	27760321	HT29	viability after 22 days	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.5170582865479704	[239,186]	[419,250,386]	6	hSpCas9	negative selection	5030988
169241887	169241909	6	-	27760321	HT29	viability after 22 days	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	1.0467582097336265	[540,421]	[1053,1067,1331]	9	hSpCas9	negative selection	5030989
169248625	169248647	6	+	27760321	HT29	viability after 22 days	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.2596164962186642	[526,410]	[649,659,636]	2	hSpCas9	negative selection	5030990
169248678	169248700	6	+	27760321	HT29	viability after 22 days	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.6908985206450492	[538,420]	[775,773,1142]	7	hSpCas9	negative selection	5030991
169248856	169248878	6	+	27760321	HT29	viability after 22 days	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.7981358301461923	[711,555]	[1245,1120,1458]	8	hSpCas9	negative selection	5030992
169237331	169237353	6	-	27760321	HT29	viability after 19 days	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.5348580049304578	[239,186]	[660,182,252]	5	hSpCas9	negative selection	5114451
169241887	169241909	6	-	27760321	HT29	viability after 19 days	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.7712031317480249	[540,421]	[1405,907,567]	7	hSpCas9	negative selection	5114452
169248625	169248647	6	+	27760321	HT29	viability after 19 days	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.6065748277355993	[526,410]	[939,694,826]	6	hSpCas9	negative selection	5114453
169248678	169248700	6	+	27760321	HT29	viability after 19 days	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	1.3863821682115542	[538,420]	[1096,1088,2058]	9	hSpCas9	negative selection	5114454
169248856	169248878	6	+	27760321	HT29	viability after 19 days	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.7327715195630964	[711,555]	[1663,1160,850]	7	hSpCas9	negative selection	5114455
169237331	169237353	6	-	27760321	HT29	viability after 16 days	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.28561762028517806	[239,186]	[383,218,280]	3	hSpCas9	negative selection	5197914
169241887	169241909	6	-	27760321	HT29	viability after 16 days	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.30793665924853253	[540,421]	[755,700,550]	3	hSpCas9	negative selection	5197915
169248625	169248647	6	+	27760321	HT29	viability after 16 days	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.3844584384874226	[526,410]	[669,655,727]	4	hSpCas9	negative selection	5197916
169248678	169248700	6	+	27760321	HT29	viability after 16 days	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.9161495566771086	[538,420]	[1164,841,1051]	9	hSpCas9	negative selection	5197917
169248856	169248878	6	+	27760321	HT29	viability after 16 days	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.7724745038916621	[711,555]	[1501,994,1170]	8	hSpCas9	negative selection	5197918
169237331	169237353	6	-	27760321	HT29	viability after 13 days	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	-0.10641460910875133	[239,186]	[170,216,297]	-1	hSpCas9	negative selection	5281377
169241887	169241909	6	-	27760321	HT29	viability after 13 days	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.8371812168282465	[540,421]	[1177,933,887]	9	hSpCas9	negative selection	5281378
169248625	169248647	6	+	27760321	HT29	viability after 13 days	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.05092324999347314	[526,410]	[444,562,675]	0	hSpCas9	negative selection	5281379
169248678	169248700	6	+	27760321	HT29	viability after 13 days	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.7470103790483708	[538,420]	[939,951,912]	8	hSpCas9	negative selection	5281380
169248856	169248878	6	+	27760321	HT29	viability after 13 days	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.55570262893166	[711,555]	[1082,1023,1132]	7	hSpCas9	negative selection	5281381
169237331	169237353	6	-	27760321	HT29	viability after 10 days	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.2936750931057426	[239,186]	[277,426,278]	4	hSpCas9	negative selection	5364840
169241887	169241909	6	-	27760321	HT29	viability after 10 days	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.30736507604530594	[540,421]	[797,687,743]	4	hSpCas9	negative selection	5364841
169248625	169248647	6	+	27760321	HT29	viability after 10 days	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.2093521018221865	[526,410]	[689,653,685]	2	hSpCas9	negative selection	5364842
169248678	169248700	6	+	27760321	HT29	viability after 10 days	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.5246077648155435	[538,420]	[936,660,979]	7	hSpCas9	negative selection	5364843
169248856	169248878	6	+	27760321	HT29	viability after 10 days	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	0.5778733219210173	[711,555]	[1318,1007,1211]	7	hSpCas9	negative selection	5364844
169237331	169237353	6	-	27760321	MOLM13	viability	TGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	1.0117892304902738	[284,239]	[256,331]	7	hSpCas9	negative selection	5448303
169241887	169241909	6	-	27760321	MOLM13	viability	CATGTCACCACCGAGTACGTGG	THBS2	ENSG00000186340	0.5788603712752893	[671,540]	[450,556]	4	hSpCas9	negative selection	5448304
169248625	169248647	6	+	27760321	MOLM13	viability	CGGGTGCCGTCAATCCAGTAGG	THBS2	ENSG00000186340	0.5316320351978159	[534,526]	[410,453]	3	hSpCas9	negative selection	5448305
169248678	169248700	6	+	27760321	MOLM13	viability	GACGATCTCGAACTGCCTCTGG	THBS2	ENSG00000186340	0.38394281654855156	[612,538]	[426,419]	2	hSpCas9	negative selection	5448306
169248856	169248878	6	+	27760321	MOLM13	viability	AAGCGGTAAGCCGGCACGCCGG	THBS2	ENSG00000186340	-0.14173235144320806	[886,711]	[553,280]	-1	hSpCas9	negative selection	5448307
169253768	169253791	6	+	27661255	K562	viability	GGACCGAGTCAGAAAGGCGCAGG	THBS2	ENSG00000186340	0.3022922689248042	[405,383]	[389,388]	8	dCas9-KRAB	negative selection	5517131
169253790	169253813	6	+	27661255	K562	viability	GCTCTGCTGGAGCGAGAGACCGG	THBS2	ENSG00000186340	-0.25087533852905963	[556,447]	[356,322]	-6	dCas9-KRAB	negative selection	5517132
169253838	169253861	6	+	27661255	K562	viability	GACGTGGCCGAGCGGCTCCCGGG	THBS2	ENSG00000186340	0.22669295728463731	[716,891]	[768,731]	7	dCas9-KRAB	negative selection	5517133
169240446	169240469	6	+	27260156	BXPC3	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.36606888971513074	[1026]	[1232,1261,1354,1743]	7	hSpCas9	negative selection	5575406
169239629	169239652	6	-	27260156	BXPC3	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.4786039512836278	[373]	[525,433,605,629]	8	hSpCas9	negative selection	5575407
169239615	169239638	6	+	27260156	BXPC3	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.4000310176589854	[126]	[225,161,97,211]	8	hSpCas9	negative selection	5575408
169240569	169240592	6	-	27260156	BXPC3	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.06494931551768529	[599]	[628,623,492,647]	-1	hSpCas9	negative selection	5639660
169246205	169246228	6	-	27260156	BXPC3	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.4593167357835286	[72]	[90,37,184,112]	8	hSpCas9	negative selection	5639661
169246239	169246262	6	-	27260156	BXPC3	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.3091002340720449	[385]	[363,561,510,580]	6	hSpCas9	negative selection	5639662
169240446	169240469	6	+	27260156	A673	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.33584278079899055	[1026]	[1595,1412,1601,1622]	7	hSpCas9	negative selection	5696657
169239629	169239652	6	-	27260156	A673	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.5694813127717625	[373]	[776,566,722,608]	9	hSpCas9	negative selection	5696658
169239615	169239638	6	+	27260156	A673	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.39310958977125066	[126]	[214,208,196,179]	8	hSpCas9	negative selection	5696659
169240569	169240592	6	-	27260156	A673	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.043555010737688915	[599]	[778,541,716,773]	-1	hSpCas9	negative selection	5760911
169246205	169246228	6	-	27260156	A673	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.6455498320411635	[72]	[236,110,89,121]	9	hSpCas9	negative selection	5760912
169246239	169246262	6	-	27260156	A673	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.5198365303100362	[385]	[690,651,627,690]	9	hSpCas9	negative selection	5760913
169240446	169240469	6	+	27260156	A375	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.5226299622584529	[1026]	[1581,1841,1508,1941]	7	hSpCas9	negative selection	5817908
169239629	169239652	6	-	27260156	A375	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.8303835053685664	[373]	[967,855,659,647]	9	hSpCas9	negative selection	5817909
169239615	169239638	6	+	27260156	A375	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.320665370670699	[126]	[203,170,173,188]	5	hSpCas9	negative selection	5817910
169240569	169240592	6	-	27260156	A375	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.0710680487232595	[599]	[451,972,745,549]	-1	hSpCas9	negative selection	5882162
169246205	169246228	6	-	27260156	A375	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.47487121223519946	[72]	[141,141,83,109]	7	hSpCas9	negative selection	5882163
169246239	169246262	6	-	27260156	A375	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.5825057222677597	[385]	[765,728,609,608]	8	hSpCas9	negative selection	5882164
169240446	169240469	6	+	27260156	COLO741	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.1472370594874164	[1026]	[1447,1288,1606]	3	hSpCas9	negative selection	5939159
169239629	169239652	6	-	27260156	COLO741	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.6143285055869332	[373]	[962,557,693]	9	hSpCas9	negative selection	5939160
169239615	169239638	6	+	27260156	COLO741	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	-0.02798084318915639	[126]	[115,190,165]	0	hSpCas9	negative selection	5939161
169240569	169240592	6	-	27260156	COLO741	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.3102826286728295	[599]	[702,574,584]	-6	hSpCas9	negative selection	6003413
169246205	169246228	6	-	27260156	COLO741	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.17182080000479916	[72]	[136,66,112]	3	hSpCas9	negative selection	6003414
169246239	169246262	6	-	27260156	COLO741	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.35048213427433816	[385]	[689,555,642]	7	hSpCas9	negative selection	6003415
169240446	169240469	6	+	27260156	CAL120	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.2610217622771389	[1026]	[1164,1586,1781]	4	hSpCas9	negative selection	6060410
169239629	169239652	6	-	27260156	CAL120	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.9770675608257244	[373]	[1334,726,751]	9	hSpCas9	negative selection	6060411
169239615	169239638	6	+	27260156	CAL120	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.12645989967964355	[126]	[123,147,236]	2	hSpCas9	negative selection	6060412
169240569	169240592	6	-	27260156	CAL120	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.08724184826498121	[599]	[664,651,783]	-1	hSpCas9	negative selection	6124664
169246205	169246228	6	-	27260156	CAL120	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.8920967571103813	[72]	[87,316,89]	9	hSpCas9	negative selection	6124665
169246239	169246262	6	-	27260156	CAL120	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.34156368965691136	[385]	[409,620,761]	5	hSpCas9	negative selection	6124666
169240446	169240469	6	+	27260156	CADOES1	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.23000813866216463	[1026]	[1036,1021,1021,1410]	4	hSpCas9	negative selection	6181661
169239629	169239652	6	-	27260156	CADOES1	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.7040048436806277	[373]	[402,831,530,498]	9	hSpCas9	negative selection	6181662
169239615	169239638	6	+	27260156	CADOES1	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.29570688234519626	[126]	[166,98,188,123]	5	hSpCas9	negative selection	6181663
169240569	169240592	6	-	27260156	CADOES1	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.1414468967371727	[599]	[501,722,585,652]	2	hSpCas9	negative selection	6245915
169246205	169246228	6	-	27260156	CADOES1	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.44551814382397614	[72]	[64,70,162,69]	7	hSpCas9	negative selection	6245916
169246239	169246262	6	-	27260156	CADOES1	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.5201237355795982	[385]	[391,503,485,683]	8	hSpCas9	negative selection	6245917
169240446	169240469	6	+	27260156	EWS502	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.4929925582039272	[1026]	[1165,1635,1551,1824]	8	hSpCas9	negative selection	6302912
169239629	169239652	6	-	27260156	EWS502	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.6058615521945772	[373]	[568,526,637,688]	9	hSpCas9	negative selection	6302913
169239615	169239638	6	+	27260156	EWS502	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.02193510456433101	[126]	[171,146,73,147]	0	hSpCas9	negative selection	6302914
169240569	169240592	6	-	27260156	EWS502	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.11450727145713824	[599]	[588,681,646,854]	2	hSpCas9	negative selection	6367166
169246205	169246228	6	-	27260156	EWS502	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.4065470171105474	[72]	[132,116,44,109]	7	hSpCas9	negative selection	6367167
169246239	169246262	6	-	27260156	EWS502	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.42439226679717684	[385]	[544,420,686,546]	7	hSpCas9	negative selection	6367168
169240446	169240469	6	+	27260156	EW8	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.43145036747062004	[1026]	[1489,907,961,1192]	7	hSpCas9	negative selection	6424163
169239629	169239652	6	-	27260156	EW8	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.9436281187554607	[373]	[557,843,422,530]	9	hSpCas9	negative selection	6424164
169239615	169239638	6	+	27260156	EW8	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.4207949819023835	[126]	[131,69,176,163]	7	hSpCas9	negative selection	6424165
169240569	169240592	6	-	27260156	EW8	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.04242755839921408	[599]	[534,531,386,454]	-1	hSpCas9	negative selection	6488417
169246205	169246228	6	-	27260156	EW8	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.2721110405974234	[72]	[81,42,21,56]	-5	hSpCas9	negative selection	6488418
169246239	169246262	6	-	27260156	EW8	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.5564381339426115	[385]	[581,402,424,447]	8	hSpCas9	negative selection	6488419
169240446	169240469	6	+	27260156	CORL105	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.47546582786425073	[1026]	[1735,1696,1852,1430]	8	hSpCas9	negative selection	6545414
169239629	169239652	6	-	27260156	CORL105	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.6302168657920126	[373]	[698,544,837,656]	9	hSpCas9	negative selection	6545415
169239615	169239638	6	+	27260156	CORL105	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.12444759770599334	[126]	[142,143,225,144]	2	hSpCas9	negative selection	6545416
169240569	169240592	6	-	27260156	CORL105	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.02081309907647838	[599]	[581,596,889,728]	0	hSpCas9	negative selection	6609668
169246205	169246228	6	-	27260156	CORL105	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.379062353474783	[72]	[64,69,139,172]	7	hSpCas9	negative selection	6609669
169246239	169246262	6	-	27260156	CORL105	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.46529045207145214	[385]	[592,672,671,562]	8	hSpCas9	negative selection	6609670
169240446	169240469	6	+	27260156	HS294T	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.32513082032811647	[1026]	[403,537,530,527]	4	hSpCas9	negative selection	6666665
169239629	169239652	6	-	27260156	HS294T	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.6637222063840833	[373]	[172,214,176,381]	8	hSpCas9	negative selection	6666666
169239615	169239638	6	+	27260156	HS294T	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	-0.5828155253395839	[126]	[8,43,41,38]	-7	hSpCas9	negative selection	6666667
169240569	169240592	6	-	27260156	HS294T	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.05066409950324097	[599]	[247,204,243,190]	0	hSpCas9	negative selection	6730919
169246205	169246228	6	-	27260156	HS294T	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.018708331530945088	[72]	[12,17,14,74]	0	hSpCas9	negative selection	6730920
169246239	169246262	6	-	27260156	HS294T	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.6568268581779744	[385]	[336,233,191,153]	8	hSpCas9	negative selection	6730921
169240446	169240469	6	+	27260156	HCC44	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.5982099412537434	[1026]	[2091,1349,2069,1652]	8	hSpCas9	negative selection	6787916
169239629	169239652	6	-	27260156	HCC44	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.7088645696619718	[373]	[731,636,672,724]	9	hSpCas9	negative selection	6787917
169239615	169239638	6	+	27260156	HCC44	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.2636444767777899	[126]	[109,163,208,205]	4	hSpCas9	negative selection	6787918
169240569	169240592	6	-	27260156	HCC44	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.17832739544274512	[599]	[512,689,609,562]	-3	hSpCas9	negative selection	6852170
169246205	169246228	6	-	27260156	HCC44	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.39874477447231804	[72]	[75,60,165,143]	6	hSpCas9	negative selection	6852171
169246239	169246262	6	-	27260156	HCC44	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.6100078539726925	[385]	[570,660,811,633]	8	hSpCas9	negative selection	6852172
169240446	169240469	6	+	27260156	G402	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.37204889554780074	[1026]	[2050,1642,1076,1765]	4	hSpCas9	negative selection	6909167
169239629	169239652	6	-	27260156	G402	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.6855437879257171	[373]	[904,595,636,807]	8	hSpCas9	negative selection	6909168
169239615	169239638	6	+	27260156	G402	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.3358828581881992	[126]	[229,178,252,126]	4	hSpCas9	negative selection	6909169
169240569	169240592	6	-	27260156	G402	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.22816042715987395	[599]	[756,827,974,850]	3	hSpCas9	negative selection	6973421
169246205	169246228	6	-	27260156	G402	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.4505341935424343	[72]	[15,200,36,9]	-5	hSpCas9	negative selection	6973422
169246239	169246262	6	-	27260156	G402	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.2545685471009307	[385]	[663,455,487,641]	3	hSpCas9	negative selection	6973423
169240446	169240469	6	+	27260156	L33	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.25090996294085977	[1026]	[1202,472,717,1386]	5	hSpCas9	negative selection	7030418
169239629	169239652	6	-	27260156	L33	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.6116665329753261	[373]	[481,230,390,619]	9	hSpCas9	negative selection	7030419
169239615	169239638	6	+	27260156	L33	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	-0.4730329962662978	[126]	[95,39,80,43]	-8	hSpCas9	negative selection	7030420
169240569	169240592	6	-	27260156	L33	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.2378186077726176	[599]	[572,179,314,519]	-5	hSpCas9	negative selection	7094672
169246205	169246228	6	-	27260156	L33	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.5313503113671794	[72]	[78,35,85,118]	9	hSpCas9	negative selection	7094673
169246239	169246262	6	-	27260156	L33	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.17255142228198594	[385]	[298,182,364,417]	4	hSpCas9	negative selection	7094674
169240446	169240469	6	+	27260156	K562	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.38624321222528546	[1026]	[1555,1259,1586,474]	5	hSpCas9	negative selection	7151669
169239629	169239652	6	-	27260156	K562	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.637026042726935	[373]	[481,527,437,601]	7	hSpCas9	negative selection	7151670
169239615	169239638	6	+	27260156	K562	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	1.8087090573648754	[126]	[200,384,511,455]	9	hSpCas9	negative selection	7151671
169240569	169240592	6	-	27260156	K562	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.5170867980560659	[599]	[943,727,691,700]	6	hSpCas9	negative selection	7215923
169246205	169246228	6	-	27260156	K562	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.325150498289708	[72]	[217,25,48,43]	4	hSpCas9	negative selection	7215924
169246239	169246262	6	-	27260156	K562	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.5276717273606909	[385]	[478,671,361,470]	6	hSpCas9	negative selection	7215925
169240446	169240469	6	+	27260156	HT29	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.52473937290116	[1026]	[1740,2027,1864,1579]	8	hSpCas9	negative selection	7272920
169239629	169239652	6	-	27260156	HT29	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.46425352719186386	[373]	[687,720,677,451]	8	hSpCas9	negative selection	7272921
169239615	169239638	6	+	27260156	HT29	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.13090570728459094	[126]	[210,176,158,135]	2	hSpCas9	negative selection	7272922
169240569	169240592	6	-	27260156	HT29	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.0056868737124494695	[599]	[870,660,742,661]	0	hSpCas9	negative selection	7337174
169246205	169246228	6	-	27260156	HT29	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.03306269040424681	[72]	[60,128,113,62]	0	hSpCas9	negative selection	7337175
169246239	169246262	6	-	27260156	HT29	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.6998815052944509	[385]	[825,793,678,752]	9	hSpCas9	negative selection	7337176
169240446	169240469	6	+	27260156	MHHES1	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.38470752313860723	[1026]	[1760,1594,1787,1018]	7	hSpCas9	negative selection	7394171
169239629	169239652	6	-	27260156	MHHES1	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.7449162799195573	[373]	[590,896,804,555]	9	hSpCas9	negative selection	7394172
169239615	169239638	6	+	27260156	MHHES1	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.7971096195917484	[126]	[122,214,314,303]	9	hSpCas9	negative selection	7394173
169240569	169240592	6	-	27260156	MHHES1	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.11531435545053276	[599]	[708,739,930,568]	2	hSpCas9	negative selection	7458425
169246205	169246228	6	-	27260156	MHHES1	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.3457510252582141	[72]	[59,75,47,71]	-6	hSpCas9	negative selection	7458426
169246239	169246262	6	-	27260156	MHHES1	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.6552153613540468	[385]	[846,559,600,713]	9	hSpCas9	negative selection	7458427
169240446	169240469	6	+	27260156	MEWO	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.5323721035342579	[1026]	[1714,1317,1198]	9	hSpCas9	negative selection	7515422
169239629	169239652	6	-	27260156	MEWO	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.3441116286582399	[373]	[378,594,344]	7	hSpCas9	negative selection	7515423
169239615	169239638	6	+	27260156	MEWO	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.37780707815122105	[126]	[214,126,132]	7	hSpCas9	negative selection	7515424
169240569	169240592	6	-	27260156	MEWO	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.23581818836498153	[599]	[600,485,366]	-5	hSpCas9	negative selection	7579676
169246205	169246228	6	-	27260156	MEWO	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.31119657651108046	[72]	[129,76,55]	6	hSpCas9	negative selection	7579677
169246239	169246262	6	-	27260156	MEWO	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.6071312850555683	[385]	[609,492,558]	9	hSpCas9	negative selection	7579678
169240446	169240469	6	+	27260156	LNCAPCLONEFGC	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.48988864575123703	[1026]	[1145,1137,1580,1414]	7	hSpCas9	negative selection	7636673
169239629	169239652	6	-	27260156	LNCAPCLONEFGC	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.46875044230609975	[373]	[448,456,493,479]	7	hSpCas9	negative selection	7636674
169239615	169239638	6	+	27260156	LNCAPCLONEFGC	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.26377113969615484	[126]	[179,72,212,100]	4	hSpCas9	negative selection	7636675
169240569	169240592	6	-	27260156	LNCAPCLONEFGC	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.32690966581813496	[599]	[409,296,571,483]	-5	hSpCas9	negative selection	7700927
169246205	169246228	6	-	27260156	LNCAPCLONEFGC	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.029359158373268635	[72]	[36,51,67,103]	0	hSpCas9	negative selection	7700928
169246239	169246262	6	-	27260156	LNCAPCLONEFGC	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.39154796986382845	[385]	[405,215,643,612]	6	hSpCas9	negative selection	7700929
169240446	169240469	6	+	27260156	PANC0327	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.5702112415914795	[1026]	[1519,1340,1325,1245]	8	hSpCas9	negative selection	7757924
169239629	169239652	6	-	27260156	PANC0327	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.5276218330756935	[373]	[581,268,477,621]	7	hSpCas9	negative selection	7757925
169239615	169239638	6	+	27260156	PANC0327	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.6157519409140173	[126]	[165,193,104,222]	8	hSpCas9	negative selection	7757926
169240569	169240592	6	-	27260156	PANC0327	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.05657377981153516	[599]	[512,572,479,475]	-1	hSpCas9	negative selection	7822178
169246205	169246228	6	-	27260156	PANC0327	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	1.2589944762078928	[72]	[77,93,63,385]	9	hSpCas9	negative selection	7822179
169246239	169246262	6	-	27260156	PANC0327	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.7357426882651925	[385]	[809,363,522,632]	9	hSpCas9	negative selection	7822180
169240446	169240469	6	+	27260156	NCIH2009	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.6856563196082659	[1026]	[2755,1887,2371]	8	hSpCas9	negative selection	7879175
169239629	169239652	6	-	27260156	NCIH2009	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.7129069506726156	[373]	[1157,614,858]	8	hSpCas9	negative selection	7879176
169239615	169239638	6	+	27260156	NCIH2009	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	-0.4135417611382062	[126]	[165,127,111]	-5	hSpCas9	negative selection	7879177
169240569	169240592	6	-	27260156	NCIH2009	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.19147396999378943	[599]	[951,520,774]	-3	hSpCas9	negative selection	7943429
169246205	169246228	6	-	27260156	NCIH2009	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.6906800633968058	[72]	[231,103,171]	8	hSpCas9	negative selection	7943430
169246239	169246262	6	-	27260156	NCIH2009	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.5534280835749426	[385]	[890,720,781]	7	hSpCas9	negative selection	7943431
169240446	169240469	6	+	27260156	NCIH1373	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.20546536968688156	[1026]	[2191,1099,1075,284]	2	hSpCas9	negative selection	8000426
169239629	169239652	6	-	27260156	NCIH1373	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.8175562055272163	[373]	[623,489,809,276]	7	hSpCas9	negative selection	8000427
169239615	169239638	6	+	27260156	NCIH1373	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	-0.11827147565869645	[126]	[233,98,158,11]	-1	hSpCas9	negative selection	8000428
169240569	169240592	6	-	27260156	NCIH1373	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.3785479516015916	[599]	[830,964,1092,147]	4	hSpCas9	negative selection	8064680
169246205	169246228	6	-	27260156	NCIH1373	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	1.413824635397144	[72]	[316,334,64,40]	9	hSpCas9	negative selection	8064681
169246239	169246262	6	-	27260156	NCIH1373	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.23223207038229737	[385]	[698,490,476,101]	2	hSpCas9	negative selection	8064682
169240446	169240469	6	+	27260156	PATU8902	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.22416470868594196	[1026]	[1529,1726,1578,1884]	2	hSpCas9	negative selection	8121677
169239629	169239652	6	-	27260156	PATU8902	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	1.0128224720749712	[373]	[732,1371,918,1232]	9	hSpCas9	negative selection	8121678
169239615	169239638	6	+	27260156	PATU8902	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	-0.0008593595687238498	[126]	[135,210,220,119]	0	hSpCas9	negative selection	8121679
169240569	169240592	6	-	27260156	PATU8902	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.03288668266846817	[599]	[1023,895,684,848]	0	hSpCas9	negative selection	8185931
169246205	169246228	6	-	27260156	PATU8902	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-1.3483284392829864	[72]	[36,4,77,27]	-8	hSpCas9	negative selection	8185932
169246239	169246262	6	-	27260156	PATU8902	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.7451382599484613	[385]	[1896,585,386,838]	7	hSpCas9	negative selection	8185933
169240446	169240469	6	+	27260156	PANC1	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.2894682440817955	[1026]	[993,1042,1566,744]	4	hSpCas9	negative selection	8242928
169239629	169239652	6	-	27260156	PANC1	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.4135709941462163	[373]	[454,703,314,305]	6	hSpCas9	negative selection	8242929
169239615	169239638	6	+	27260156	PANC1	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	-0.06515629060205841	[126]	[131,82,82,110]	-1	hSpCas9	negative selection	8242930
169240569	169240592	6	-	27260156	PANC1	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.07821201133484312	[599]	[403,549,548,460]	-1	hSpCas9	negative selection	8307182
169246205	169246228	6	-	27260156	PANC1	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.1483575198626661	[72]	[82,7,54,66]	-2	hSpCas9	negative selection	8307183
169246239	169246262	6	-	27260156	PANC1	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.42508230592496493	[385]	[516,482,502,300]	7	hSpCas9	negative selection	8307184
169240446	169240469	6	+	27260156	PANC0813	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.4139281810868769	[1026]	[1671,1857,1471,1438]	6	hSpCas9	negative selection	8364179
169239629	169239652	6	-	27260156	PANC0813	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.22658931385844117	[373]	[702,447,522,404]	3	hSpCas9	negative selection	8364180
169239615	169239638	6	+	27260156	PANC0813	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	-0.17594821918277725	[126]	[168,102,171,89]	-3	hSpCas9	negative selection	8364181
169240569	169240592	6	-	27260156	PANC0813	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.07488113941783447	[599]	[608,724,703,633]	-1	hSpCas9	negative selection	8428433
169246205	169246228	6	-	27260156	PANC0813	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.2701529334952406	[72]	[103,59,81,42]	-4	hSpCas9	negative selection	8428434
169246239	169246262	6	-	27260156	PANC0813	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.06544593319258452	[385]	[642,533,473,272]	1	hSpCas9	negative selection	8428435
169240446	169240469	6	+	27260156	RDES	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.2520249680778801	[1026]	[1247,1339,1606,1438]	4	hSpCas9	negative selection	8485430
169239629	169239652	6	-	27260156	RDES	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.651571689592306	[373]	[538,771,716,674]	9	hSpCas9	negative selection	8485431
169239615	169239638	6	+	27260156	RDES	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.13087291254790312	[126]	[149,110,148,243]	2	hSpCas9	negative selection	8485432
169240569	169240592	6	-	27260156	RDES	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.10759475031498325	[599]	[648,461,664,805]	-2	hSpCas9	negative selection	8549684
169246205	169246228	6	-	27260156	RDES	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.5012726162694143	[72]	[86,126,130,135]	7	hSpCas9	negative selection	8549685
169246239	169246262	6	-	27260156	RDES	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.30594347194136506	[385]	[489,594,442,671]	5	hSpCas9	negative selection	8549686
169240446	169240469	6	+	27260156	PC3	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.342453296680423	[1026]	[953,1137,2327,1182]	7	hSpCas9	negative selection	8606681
169239629	169239652	6	-	27260156	PC3	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.22516278810319243	[373]	[319,381,667,469]	5	hSpCas9	negative selection	8606682
169239615	169239638	6	+	27260156	PC3	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.5660791004363004	[126]	[59,253,521,80]	9	hSpCas9	negative selection	8606683
169240569	169240592	6	-	27260156	PC3	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.25165135312208176	[599]	[503,998,1085,384]	5	hSpCas9	negative selection	8670935
169246205	169246228	6	-	27260156	PC3	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.1772896558642172	[72]	[69,62,141,72]	4	hSpCas9	negative selection	8670936
169246239	169246262	6	-	27260156	PC3	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.5555178753393839	[385]	[295,519,988,701]	9	hSpCas9	negative selection	8670937
169240446	169240469	6	+	27260156	PATU8988T	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.3480791762209723	[1026]	[1444,1176,1168,1253]	6	hSpCas9	negative selection	8727932
169239629	169239652	6	-	27260156	PATU8988T	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.793567958676691	[373]	[760,663,561,513]	9	hSpCas9	negative selection	8727933
169239615	169239638	6	+	27260156	PATU8988T	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.8506392146104744	[126]	[149,264,152,330]	9	hSpCas9	negative selection	8727934
169240569	169240592	6	-	27260156	PATU8988T	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.1559824137531015	[599]	[632,811,531,621]	2	hSpCas9	negative selection	8792186
169246205	169246228	6	-	27260156	PATU8988T	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.23656833165450086	[72]	[16,75,73,74]	-4	hSpCas9	negative selection	8792187
169246239	169246262	6	-	27260156	PATU8988T	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.5684257496632223	[385]	[407,758,591,464]	8	hSpCas9	negative selection	8792188
169240446	169240469	6	+	27260156	T47D	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.36646406087807915	[1026]	[1763,1337,1562,1521]	7	hSpCas9	negative selection	8849183
169239629	169239652	6	-	27260156	T47D	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.5611477520670477	[373]	[695,618,634,622]	9	hSpCas9	negative selection	8849184
169239615	169239638	6	+	27260156	T47D	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.10104482966050221	[126]	[179,175,177,96]	2	hSpCas9	negative selection	8849185
169240569	169240592	6	-	27260156	T47D	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.011301434046975367	[599]	[731,687,682,670]	0	hSpCas9	negative selection	8913437
169246205	169246228	6	-	27260156	T47D	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.3422165371411898	[72]	[172,65,76,119]	7	hSpCas9	negative selection	8913438
169246239	169246262	6	-	27260156	T47D	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.5360664370810247	[385]	[675,666,599,664]	9	hSpCas9	negative selection	8913439
169240446	169240469	6	+	27260156	SU8686	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.32442432466497384	[1026]	[1223,1251,1151,1504]	5	hSpCas9	negative selection	8970434
169239629	169239652	6	-	27260156	SU8686	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.7363013284871518	[373]	[496,563,679,772]	9	hSpCas9	negative selection	8970435
169239615	169239638	6	+	27260156	SU8686	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	-0.13411358251402383	[126]	[145,130,88,79]	-2	hSpCas9	negative selection	8970436
169240569	169240592	6	-	27260156	SU8686	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.19911634123566688	[599]	[353,418,642,720]	-3	hSpCas9	negative selection	9034688
169246205	169246228	6	-	27260156	SU8686	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	-0.09012252274538746	[72]	[60,109,17,77]	-2	hSpCas9	negative selection	9034689
169246239	169246262	6	-	27260156	SU8686	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.48471914949769307	[385]	[506,473,548,635]	7	hSpCas9	negative selection	9034690
169240446	169240469	6	+	27260156	SKES1	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.3245700713117461	[1026]	[1610,1568,1217,852]	6	hSpCas9	negative selection	9091685
169239629	169239652	6	-	27260156	SKES1	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.6758466031118446	[373]	[657,682,507,553]	9	hSpCas9	negative selection	9091686
169239615	169239638	6	+	27260156	SKES1	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.13536898839012035	[126]	[207,133,116,108]	3	hSpCas9	negative selection	9091687
169240569	169240592	6	-	27260156	SKES1	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.09135056849013201	[599]	[538,809,795,428]	2	hSpCas9	negative selection	9155939
169246205	169246228	6	-	27260156	SKES1	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.3207580134471506	[72]	[76,132,82,74]	6	hSpCas9	negative selection	9155940
169246239	169246262	6	-	27260156	SKES1	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.5917809730600185	[385]	[697,647,542,464]	9	hSpCas9	negative selection	9155941
169240446	169240469	6	+	27260156	TOV112D	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.47882623147056336	[1026]	[1464,1902,1386,1103]	8	hSpCas9	negative selection	9212936
169239629	169239652	6	-	27260156	TOV112D	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.4334506376381572	[373]	[496,712,399,463]	7	hSpCas9	negative selection	9212937
169239615	169239638	6	+	27260156	TOV112D	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.35156363428254545	[126]	[82,192,218,154]	6	hSpCas9	negative selection	9212938
169240569	169240592	6	-	27260156	TOV112D	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.25726141323360396	[599]	[866,848,682,522]	5	hSpCas9	negative selection	9277190
169246205	169246228	6	-	27260156	TOV112D	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.4687442984625245	[72]	[150,69,75,103]	8	hSpCas9	negative selection	9277191
169246239	169246262	6	-	27260156	TOV112D	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.3247527431064559	[385]	[299,495,520,602]	6	hSpCas9	negative selection	9277192
169240446	169240469	6	+	27260156	TC71	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.41723466137272225	[1026]	[1444,1255,1593,1588]	8	hSpCas9	negative selection	9334187
169239629	169239652	6	-	27260156	TC71	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.534625389486408	[373]	[544,538,588,654]	9	hSpCas9	negative selection	9334188
169239615	169239638	6	+	27260156	TC71	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.33188148336994594	[126]	[263,130,128,159]	7	hSpCas9	negative selection	9334189
169240569	169240592	6	-	27260156	TC71	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	-0.09366977999378429	[599]	[549,584,639,637]	-2	hSpCas9	negative selection	9398441
169246205	169246228	6	-	27260156	TC71	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.041874161547311495	[72]	[100,94,74,48]	1	hSpCas9	negative selection	9398442
169246239	169246262	6	-	27260156	TC71	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.3663414807579375	[385]	[564,531,490,546]	8	hSpCas9	negative selection	9398443
169240446	169240469	6	+	27260156	TC32	viability	CCTCACCTTGCAGGTACACGTGG	THBS2	ENSG00000186340	0.24791409360855265	[1026]	[1077,667,1432,1606]	4	hSpCas9	negative selection	9455438
169239629	169239652	6	-	27260156	TC32	viability	CTGCGCCAGTCCATCCTTTGTGG	THBS2	ENSG00000186340	0.41479369067463034	[373]	[401,320,726,508]	7	hSpCas9	negative selection	9455439
169239615	169239638	6	+	27260156	TC32	viability	GCAGCATTCGCCTTCCACAAAGG	THBS2	ENSG00000186340	0.06948427441456873	[126]	[127,80,148,157]	1	hSpCas9	negative selection	9455440
169240569	169240592	6	-	27260156	TC32	viability	CGAATGATAACCAGTTTCTCTGG	THBS2	ENSG00000186340	0.04303624986519766	[599]	[452,558,806,528]	0	hSpCas9	negative selection	9519692
169246205	169246228	6	-	27260156	TC32	viability	AGCAAGAAGGGTTGCCAGCAAGG	THBS2	ENSG00000186340	0.14120543099169724	[72]	[53,95,68,71]	2	hSpCas9	negative selection	9519693
169246239	169246262	6	-	27260156	TC32	viability	CCTAGTGTTTGAAAACTCTGTGG	THBS2	ENSG00000186340	0.2833450039588254	[385]	[519,347,492,408]	5	hSpCas9	negative selection	9519694
169237790	169237813	6	-	27869803	HPAFII	viability after 27 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.18109120069809626	[326]	[255,143,NaN]	1	hSpCas9	negative selection	9594441
169239619	169239642	6	+	27869803	HPAFII	viability after 27 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	0.8515592584049752	[146]	[133,143,NaN]	7	hSpCas9	negative selection	9594442
169240559	169240582	6	+	27869803	HPAFII	viability after 27 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	1.0725812006577873	[367]	[365,440,NaN]	8	hSpCas9	negative selection	9594443
169241761	169241784	6	-	27869803	HPAFII	viability after 27 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.32708011855489105	[156]	[84,118,NaN]	2	hSpCas9	negative selection	9594444
169248814	169248837	6	+	27869803	HPAFII	viability after 27 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.9791107550157854	[189]	[149,235,NaN]	7	hSpCas9	negative selection	9594445
169250732	169250755	6	-	27869803	HPAFII	viability after 27 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.7458814738123856	[589]	[295,706,NaN]	6	hSpCas9	negative selection	9594446
169237790	169237813	6	-	27869803	HPAFII	viability after 15 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	-0.038009584328560386	[326]	[501,242,NaN]	0	hSpCas9	negative selection	9676890
169239619	169239642	6	+	27869803	HPAFII	viability after 15 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	0.6976869610098804	[146]	[291,233,NaN]	7	hSpCas9	negative selection	9676891
169240559	169240582	6	+	27869803	HPAFII	viability after 15 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.358129724742805	[367]	[731,366,NaN]	4	hSpCas9	negative selection	9676892
169241761	169241784	6	-	27869803	HPAFII	viability after 15 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.6079317741842868	[156]	[369,186,NaN]	7	hSpCas9	negative selection	9676893
169248814	169248837	6	+	27869803	HPAFII	viability after 15 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	1.1694031443260813	[189]	[433,474,NaN]	9	hSpCas9	negative selection	9676894
169250732	169250755	6	-	27869803	HPAFII	viability after 15 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.26661961527145883	[589]	[784,748,NaN]	3	hSpCas9	negative selection	9676895
169237790	169237813	6	-	27869803	ASPC1	viability after 36 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.8229920657521095	[744]	[633,385,391]	7	hSpCas9	negative selection	9759339
169239619	169239642	6	+	27869803	ASPC1	viability after 36 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	-0.11181071095866513	[383]	[166,115,98]	-1	hSpCas9	negative selection	9759340
169240559	169240582	6	+	27869803	ASPC1	viability after 36 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.2968771806503857	[940]	[376,415,407]	3	hSpCas9	negative selection	9759341
169241761	169241784	6	-	27869803	ASPC1	viability after 36 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.2632211896277453	[452]	[307,79,191]	2	hSpCas9	negative selection	9759342
169248814	169248837	6	+	27869803	ASPC1	viability after 36 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	-0.5947581326776763	[643]	[221,8,206]	-5	hSpCas9	negative selection	9759343
169250732	169250755	6	-	27869803	ASPC1	viability after 36 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	-0.5165681627504004	[1296]	[338,258,342]	-5	hSpCas9	negative selection	9759344
169237790	169237813	6	-	27869803	PATU8988S	viability after 35 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.6545894944592385	[637]	[399,408,NaN]	7	hSpCas9	negative selection	9841788
169239619	169239642	6	+	27869803	PATU8988S	viability after 35 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	0.8193884164657378	[449]	[241,397,NaN]	8	hSpCas9	negative selection	9841789
169240559	169240582	6	+	27869803	PATU8988S	viability after 35 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.4891040407269678	[820]	[508,418,NaN]	5	hSpCas9	negative selection	9841790
169241761	169241784	6	-	27869803	PATU8988S	viability after 35 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.4655726341542067	[434]	[207,275,NaN]	5	hSpCas9	negative selection	9841791
169248814	169248837	6	+	27869803	PATU8988S	viability after 35 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.5627252423789217	[491]	[372,211,NaN]	6	hSpCas9	negative selection	9841792
169250732	169250755	6	-	27869803	PATU8988S	viability after 35 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.7028046073835919	[1231]	[863,750,NaN]	7	hSpCas9	negative selection	9841793
169237790	169237813	6	-	27869803	PATU8988S	viability after 31 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.5710113737080877	[637]	[402,345,NaN]	6	hSpCas9	negative selection	9924237
169239619	169239642	6	+	27869803	PATU8988S	viability after 31 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	0.5676609389320424	[449]	[184,368,NaN]	6	hSpCas9	negative selection	9924238
169240559	169240582	6	+	27869803	PATU8988S	viability after 31 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	0.5130958342196146	[820]	[420,525,NaN]	6	hSpCas9	negative selection	9924239
169241761	169241784	6	-	27869803	PATU8988S	viability after 31 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	-0.24981275031040284	[434]	[122,174,NaN]	-3	hSpCas9	negative selection	9924240
169248814	169248837	6	+	27869803	PATU8988S	viability after 31 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.3438100904956377	[491]	[321,155,NaN]	4	hSpCas9	negative selection	9924241
169250732	169250755	6	-	27869803	PATU8988S	viability after 31 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.7583026439607192	[1231]	[599,1124,NaN]	8	hSpCas9	negative selection	9924242
169237790	169237813	6	-	27869803	HPAFII	viability after 35 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.3926199189718286	[326]	[269,157,NaN]	2	hSpCas9	negative selection	10006686
169239619	169239642	6	+	27869803	HPAFII	viability after 35 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	0.969817185780119	[146]	[125,167,NaN]	6	hSpCas9	negative selection	10006687
169240559	169240582	6	+	27869803	HPAFII	viability after 35 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	1.0670845870685137	[367]	[466,303,NaN]	7	hSpCas9	negative selection	10006688
169241761	169241784	6	-	27869803	HPAFII	viability after 35 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	-0.09271321817561107	[156]	[82,64,NaN]	0	hSpCas9	negative selection	10006689
169248814	169248837	6	+	27869803	HPAFII	viability after 35 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.6244962186811118	[189]	[136,160,NaN]	4	hSpCas9	negative selection	10006690
169250732	169250755	6	-	27869803	HPAFII	viability after 35 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.8108968802240932	[589]	[253,827,NaN]	5	hSpCas9	negative selection	10006691
169237790	169237813	6	-	27869803	HPAFII	viability after 31 days	TTTGCTTCCTCTGGCAGCGGTGG	THBS2	ENSG00000186340	0.5493863986845711	[326]	[325,205,NaN]	4	hSpCas9	negative selection	10089135
169239619	169239642	6	+	27869803	HPAFII	viability after 31 days	CATTCGCCTTCCACAAAGGATGG	THBS2	ENSG00000186340	1.1145179008935913	[146]	[147,211,NaN]	8	hSpCas9	negative selection	10089136
169240559	169240582	6	+	27869803	HPAFII	viability after 31 days	CAATGAGCTCCCAGAGAAACTGG	THBS2	ENSG00000186340	1.1618928230162973	[367]	[497,422,NaN]	8	hSpCas9	negative selection	10089137
169241761	169241784	6	-	27869803	HPAFII	viability after 31 days	CAGCGAGAACCTCAAGAGAGTGG	THBS2	ENSG00000186340	0.7015733365407291	[156]	[160,123,NaN]	5	hSpCas9	negative selection	10089138
169248814	169248837	6	+	27869803	HPAFII	viability after 31 days	AGGTCATCTGCGTTCACCGGTGG	THBS2	ENSG00000186340	0.8980155146998792	[189]	[113,290,NaN]	6	hSpCas9	negative selection	10089139
169250732	169250755	6	-	27869803	HPAFII	viability after 31 days	TGGGTGTGGCCCAGCACGCAAGG	THBS2	ENSG00000186340	0.8613409023928056	[589]	[222,1013,NaN]	6	hSpCas9	negative selection	10089140
169222200	169222223	6	-	28162770	P31FUJ	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	1.0667580774445293	[77]	[191]	9	hSpCas9	negative selection	10250217
169237184	169237207	6	-	28162770	P31FUJ	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	0.15738010617818943	[160]	[210]	1	hSpCas9	negative selection	10250218
169248689	169248712	6	+	28162770	P31FUJ	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	0.35633597227797076	[114]	[172]	4	hSpCas9	negative selection	10250219
169248557	169248580	6	-	28162770	P31FUJ	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	0.20426160119446413	[324]	[439]	2	hSpCas9	negative selection	10250220
169246199	169246222	6	-	28162770	P31FUJ	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	0.1297678749703295	[132]	[170]	1	hSpCas9	negative selection	10250221
169241879	169241902	6	+	28162770	P31FUJ	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.47636027881203613	[240]	[393]	5	hSpCas9	negative selection	10250222
169241818	169241841	6	-	28162770	P31FUJ	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.47916557304209795	[325]	[533]	5	hSpCas9	negative selection	10250223
169239640	169239663	6	+	28162770	P31FUJ	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.5928485432339626	[346]	[614]	6	hSpCas9	negative selection	10250224
169237331	169237354	6	-	28162770	P31FUJ	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.8482124839586809	[276]	[585]	8	hSpCas9	negative selection	10250225
169237302	169237325	6	+	28162770	P31FUJ	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	0.6420560423081374	[336]	[617]	7	hSpCas9	negative selection	10250226
169222200	169222223	6	-	28162770	TF1	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	NaN	[NaN]	[84]	1	hSpCas9	negative selection	10419583
169237184	169237207	6	-	28162770	TF1	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	NaN	[NaN]	[193]	1	hSpCas9	negative selection	10419584
169248689	169248712	6	+	28162770	TF1	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10419585
169248557	169248580	6	-	28162770	TF1	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	NaN	[NaN]	[449]	1	hSpCas9	negative selection	10419586
169246199	169246222	6	-	28162770	TF1	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10419587
169241879	169241902	6	+	28162770	TF1	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	NaN	[NaN]	[351]	1	hSpCas9	negative selection	10419588
169241818	169241841	6	-	28162770	TF1	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	NaN	[NaN]	[516]	1	hSpCas9	negative selection	10419589
169239640	169239663	6	+	28162770	TF1	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	NaN	[NaN]	[178]	1	hSpCas9	negative selection	10419590
169237331	169237354	6	-	28162770	TF1	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	NaN	[NaN]	[253]	1	hSpCas9	negative selection	10419591
169237302	169237325	6	+	28162770	TF1	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	NaN	[NaN]	[257]	1	hSpCas9	negative selection	10419592
169222200	169222223	6	-	28162770	SKM1	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	-0.06300979752580038	[25]	[43]	0	hSpCas9	negative selection	10588949
169237184	169237207	6	-	28162770	SKM1	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	-0.8678053876351302	[31]	[30]	-6	hSpCas9	negative selection	10588950
169248689	169248712	6	+	28162770	SKM1	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	0.39030190569085865	[40]	[94]	4	hSpCas9	negative selection	10588951
169248557	169248580	6	-	28162770	SKM1	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	-0.06094042823833623	[94]	[160]	0	hSpCas9	negative selection	10588952
169246199	169246222	6	-	28162770	SKM1	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	1.2461698046195737	[30]	[129]	9	hSpCas9	negative selection	10588953
169241879	169241902	6	+	28162770	SKM1	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.9297392488245992	[67]	[228]	8	hSpCas9	negative selection	10588954
169241818	169241841	6	-	28162770	SKM1	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.13846993779135713	[73]	[143]	1	hSpCas9	negative selection	10588955
169239640	169239663	6	+	28162770	SKM1	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.06657701930957144	[73]	[136]	0	hSpCas9	negative selection	10588956
169237331	169237354	6	-	28162770	SKM1	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.13677563925148167	[70]	[137]	1	hSpCas9	negative selection	10588957
169237302	169237325	6	+	28162770	SKM1	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	0.10584851622215918	[81]	[155]	1	hSpCas9	negative selection	10588958
169222200	169222223	6	-	28162770	SKM1	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	-0.06300979752580038	[25]	[43]	0	hSpCas9	negative selection	10758315
169237184	169237207	6	-	28162770	SKM1	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	-0.8678053876351302	[31]	[30]	-6	hSpCas9	negative selection	10758316
169248689	169248712	6	+	28162770	SKM1	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	0.39030190569085865	[40]	[94]	4	hSpCas9	negative selection	10758317
169248557	169248580	6	-	28162770	SKM1	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	-0.06094042823833623	[94]	[160]	0	hSpCas9	negative selection	10758318
169246199	169246222	6	-	28162770	SKM1	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	1.2461698046195737	[30]	[129]	9	hSpCas9	negative selection	10758319
169241879	169241902	6	+	28162770	SKM1	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.9297392488245992	[67]	[228]	8	hSpCas9	negative selection	10758320
169241818	169241841	6	-	28162770	SKM1	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.13846993779135713	[73]	[143]	1	hSpCas9	negative selection	10758321
169239640	169239663	6	+	28162770	SKM1	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.06657701930957144	[73]	[136]	0	hSpCas9	negative selection	10758322
169237331	169237354	6	-	28162770	SKM1	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.13677563925148167	[70]	[137]	1	hSpCas9	negative selection	10758323
169237302	169237325	6	+	28162770	SKM1	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	0.10584851622215918	[81]	[155]	1	hSpCas9	negative selection	10758324
169222200	169222223	6	-	28162770	PL21	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	0.8201085650383896	[94]	[72]	7	hSpCas9	negative selection	10927681
169237184	169237207	6	-	28162770	PL21	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	-0.9022221031403578	[145]	[33]	-6	hSpCas9	negative selection	10927682
169248689	169248712	6	+	28162770	PL21	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	-0.2873063803175738	[142]	[50]	-2	hSpCas9	negative selection	10927683
169248557	169248580	6	-	28162770	PL21	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	0.5894140177030822	[338]	[221]	5	hSpCas9	negative selection	10927684
169246199	169246222	6	-	28162770	PL21	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	-0.9697853869529923	[125]	[27]	-6	hSpCas9	negative selection	10927685
169241879	169241902	6	+	28162770	PL21	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.04363512880932938	[213]	[95]	0	hSpCas9	negative selection	10927686
169241818	169241841	6	-	28162770	PL21	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.39464263865229837	[193]	[110]	3	hSpCas9	negative selection	10927687
169239640	169239663	6	+	28162770	PL21	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	-0.2124588393381065	[196]	[73]	-1	hSpCas9	negative selection	10927688
169237331	169237354	6	-	28162770	PL21	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	-0.5498821325023325	[221]	[65]	-4	hSpCas9	negative selection	10927689
169237302	169237325	6	+	28162770	PL21	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	0.832630485293062	[208]	[161]	7	hSpCas9	negative selection	10927690
169222200	169222223	6	-	28162770	P31FUJ	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	1.0667580774445293	[77]	[191]	9	hSpCas9	negative selection	11097047
169237184	169237207	6	-	28162770	P31FUJ	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	0.15738010617818943	[160]	[210]	1	hSpCas9	negative selection	11097048
169248689	169248712	6	+	28162770	P31FUJ	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	0.35633597227797076	[114]	[172]	4	hSpCas9	negative selection	11097049
169248557	169248580	6	-	28162770	P31FUJ	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	0.20426160119446413	[324]	[439]	2	hSpCas9	negative selection	11097050
169246199	169246222	6	-	28162770	P31FUJ	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	0.1297678749703295	[132]	[170]	1	hSpCas9	negative selection	11097051
169241879	169241902	6	+	28162770	P31FUJ	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.47636027881203613	[240]	[393]	5	hSpCas9	negative selection	11097052
169241818	169241841	6	-	28162770	P31FUJ	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.47916557304209795	[325]	[533]	5	hSpCas9	negative selection	11097053
169239640	169239663	6	+	28162770	P31FUJ	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.5928485432339626	[346]	[614]	6	hSpCas9	negative selection	11097054
169237331	169237354	6	-	28162770	P31FUJ	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.8482124839586809	[276]	[585]	8	hSpCas9	negative selection	11097055
169237302	169237325	6	+	28162770	P31FUJ	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	0.6420560423081374	[336]	[617]	7	hSpCas9	negative selection	11097056
169222200	169222223	6	-	28162770	OCIAML5	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	2.1228424481731727	[28]	[227]	9	hSpCas9	negative selection	11266413
169237184	169237207	6	-	28162770	OCIAML5	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	-0.7660933477541442	[113]	[120]	-5	hSpCas9	negative selection	11266414
169248689	169248712	6	+	28162770	OCIAML5	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	0.6115896336350255	[61]	[170]	5	hSpCas9	negative selection	11266415
169248557	169248580	6	-	28162770	OCIAML5	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	0.45924784999851354	[190]	[473]	4	hSpCas9	negative selection	11266416
169246199	169246222	6	-	28162770	OCIAML5	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	-0.27917690244341586	[79]	[118]	-2	hSpCas9	negative selection	11266417
169241879	169241902	6	+	28162770	OCIAML5	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	1.067656839792088	[96]	[366]	8	hSpCas9	negative selection	11266418
169241818	169241841	6	-	28162770	OCIAML5	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.5339918614430812	[131]	[344]	4	hSpCas9	negative selection	11266419
169239640	169239663	6	+	28162770	OCIAML5	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.8148375433933355	[153]	[488]	7	hSpCas9	negative selection	11266420
169237331	169237354	6	-	28162770	OCIAML5	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.2059655505074181	[133]	[278]	1	hSpCas9	negative selection	11266421
169237302	169237325	6	+	28162770	OCIAML5	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	0.2353962703863426	[207]	[441]	2	hSpCas9	negative selection	11266422
169222200	169222223	6	-	28162770	EOL1	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	-1.1839766852076348	[206]	[47]	-7	hSpCas9	negative selection	11435779
169237184	169237207	6	-	28162770	EOL1	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	0.11010342472661105	[152]	[86]	1	hSpCas9	negative selection	11435780
169248689	169248712	6	+	28162770	EOL1	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	0.9007991687979258	[244]	[240]	7	hSpCas9	negative selection	11435781
169248557	169248580	6	-	28162770	EOL1	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	0.2752123943774485	[675]	[430]	2	hSpCas9	negative selection	11435782
169246199	169246222	6	-	28162770	EOL1	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	-0.6737115517640795	[326]	[107]	-5	hSpCas9	negative selection	11435783
169241879	169241902	6	+	28162770	EOL1	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.2671993454676964	[469]	[297]	2	hSpCas9	negative selection	11435784
169241818	169241841	6	-	28162770	EOL1	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	1.3976716319351032	[285]	[396]	9	hSpCas9	negative selection	11435785
169239640	169239663	6	+	28162770	EOL1	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	-0.6059669451282452	[389]	[134]	-4	hSpCas9	negative selection	11435786
169237331	169237354	6	-	28162770	EOL1	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.17312412471063754	[233]	[138]	1	hSpCas9	negative selection	11435787
169237302	169237325	6	+	28162770	EOL1	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	-0.06114439174558187	[300]	[151]	0	hSpCas9	negative selection	11435788
169222200	169222223	6	-	28162770	MOLM13	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	-0.20686978952722324	[173]	[108]	-1	hSpCas9	negative selection	11605145
169237184	169237207	6	-	28162770	MOLM13	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	0.1984994806709614	[181]	[150]	1	hSpCas9	negative selection	11605146
169248689	169248712	6	+	28162770	MOLM13	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	-0.008548662398408291	[223]	[160]	0	hSpCas9	negative selection	11605147
169248557	169248580	6	-	28162770	MOLM13	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	1.0178454324378217	[583]	[854]	7	hSpCas9	negative selection	11605148
169246199	169246222	6	-	28162770	MOLM13	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	0.05038362667498553	[194]	[145]	0	hSpCas9	negative selection	11605149
169241879	169241902	6	+	28162770	MOLM13	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	-0.3413904174375174	[374]	[213]	-2	hSpCas9	negative selection	11605150
169241818	169241841	6	-	28162770	MOLM13	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	1.160011548614568	[280]	[453]	8	hSpCas9	negative selection	11605151
169239640	169239663	6	+	28162770	MOLM13	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	1.3231039423807747	[287]	[520]	8	hSpCas9	negative selection	11605152
169237331	169237354	6	-	28162770	MOLM13	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	-0.3626978467507424	[312]	[175]	-2	hSpCas9	negative selection	11605153
169237302	169237325	6	+	28162770	MOLM13	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	0.10977895035057031	[322]	[251]	0	hSpCas9	negative selection	11605154
169222200	169222223	6	-	28162770	HEL	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	0.23611357253771326	[113]	[85]	2	hSpCas9	negative selection	11774511
169237184	169237207	6	-	28162770	HEL	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	0.33239871138820637	[154]	[124]	2	hSpCas9	negative selection	11774512
169248689	169248712	6	+	28162770	HEL	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	-0.15131926744378926	[188]	[108]	-1	hSpCas9	negative selection	11774513
169248557	169248580	6	-	28162770	HEL	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	0.5032100667093315	[498]	[452]	4	hSpCas9	negative selection	11774514
169246199	169246222	6	-	28162770	HEL	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	0.24112184848383467	[213]	[161]	2	hSpCas9	negative selection	11774515
169241879	169241902	6	+	28162770	HEL	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.9237946454721914	[357]	[434]	7	hSpCas9	negative selection	11774516
169241818	169241841	6	-	28162770	HEL	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.9447061851568317	[261]	[322]	7	hSpCas9	negative selection	11774517
169239640	169239663	6	+	28162770	HEL	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.2146451798960669	[295]	[219]	1	hSpCas9	negative selection	11774518
169237331	169237354	6	-	28162770	HEL	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	-0.5796535893360908	[286]	[122]	-4	hSpCas9	negative selection	11774519
169237302	169237325	6	+	28162770	HEL	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	-0.06775455080465809	[305]	[186]	0	hSpCas9	negative selection	11774520
169222200	169222223	6	-	28162770	MV411	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	0.5494660882324329	[72]	[89]	5	hSpCas9	negative selection	11943877
169237184	169237207	6	-	28162770	MV411	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	0.02860294885951653	[134]	[115]	0	hSpCas9	negative selection	11943878
169248689	169248712	6	+	28162770	MV411	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	0.24743755078277546	[122]	[122]	2	hSpCas9	negative selection	11943879
169248557	169248580	6	-	28162770	MV411	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	0.2474375507827754	[321]	[321]	2	hSpCas9	negative selection	11943880
169246199	169246222	6	-	28162770	MV411	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	0.10683922060997458	[139]	[126]	0	hSpCas9	negative selection	11943881
169241879	169241902	6	+	28162770	MV411	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.2963471512637217	[260]	[269]	2	hSpCas9	negative selection	11943882
169241818	169241841	6	-	28162770	MV411	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.5908140649341727	[226]	[287]	5	hSpCas9	negative selection	11943883
169239640	169239663	6	+	28162770	MV411	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.2407738205017645	[216]	[215]	2	hSpCas9	negative selection	11943884
169237331	169237354	6	-	28162770	MV411	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.11050190542666705	[253]	[230]	0	hSpCas9	negative selection	11943885
169237302	169237325	6	+	28162770	MV411	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	1.3088380954469188	[183]	[383]	9	hSpCas9	negative selection	11943886
169222200	169222223	6	-	28162770	MONOMAC1	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	1.2359225602165527	[79]	[215]	9	hSpCas9	negative selection	12113243
169237184	169237207	6	-	28162770	MONOMAC1	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	0.9206581956102009	[99]	[216]	8	hSpCas9	negative selection	12113244
169248689	169248712	6	+	28162770	MONOMAC1	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	0.5947212199470319	[92]	[160]	6	hSpCas9	negative selection	12113245
169248557	169248580	6	-	28162770	MONOMAC1	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	0.8392385393319962	[215]	[442]	7	hSpCas9	negative selection	12113246
169246199	169246222	6	-	28162770	MONOMAC1	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	0.14779164993788746	[99]	[126]	1	hSpCas9	negative selection	12113247
169241879	169241902	6	+	28162770	MONOMAC1	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	-0.01758907149873451	[150]	[170]	0	hSpCas9	negative selection	12113248
169241818	169241841	6	-	28162770	MONOMAC1	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.28012236412708746	[124]	[173]	3	hSpCas9	negative selection	12113249
169239640	169239663	6	+	28162770	MONOMAC1	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.5969114164469005	[138]	[240]	6	hSpCas9	negative selection	12113250
169237331	169237354	6	-	28162770	MONOMAC1	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.10442714526809288	[141]	[174]	1	hSpCas9	negative selection	12113251
169237302	169237325	6	+	28162770	MONOMAC1	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	1.7961418870844323	[105]	[421]	9	hSpCas9	negative selection	12113252
169222200	169222223	6	-	28162770	OCIAML2	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	0.4191872570074159	[16]	[125]	4	hSpCas9	negative selection	12282609
169237184	169237207	6	-	28162770	OCIAML2	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	0.12182721202591926	[31]	[192]	1	hSpCas9	negative selection	12282610
169248689	169248712	6	+	28162770	OCIAML2	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	1.1687804595013713	[25]	[323]	9	hSpCas9	negative selection	12282611
169248557	169248580	6	-	28162770	OCIAML2	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	-0.022648227348402106	[91]	[501]	0	hSpCas9	negative selection	12282612
169246199	169246222	6	-	28162770	OCIAML2	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	-0.4200037521721933	[27]	[115]	-3	hSpCas9	negative selection	12282613
169241879	169241902	6	+	28162770	OCIAML2	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.6168330160081781	[45]	[390]	6	hSpCas9	negative selection	12282614
169241818	169241841	6	-	28162770	OCIAML2	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.40063686063563597	[40]	[299]	4	hSpCas9	negative selection	12282615
169239640	169239663	6	+	28162770	OCIAML2	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	0.3252294579776134	[53]	[374]	3	hSpCas9	negative selection	12282616
169237331	169237354	6	-	28162770	OCIAML2	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	1.4272156307633506	[31]	[476]	9	hSpCas9	negative selection	12282617
169237302	169237325	6	+	28162770	OCIAML2	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	0.2188886065215847	[50]	[328]	2	hSpCas9	negative selection	12282618
169222200	169222223	6	-	28162770	OCIAML3	viability	GGCACACGGGGAACACGCCGGGG	THBS2	ENSG00000186340	0.10113777814741581	[41]	[135]	1	hSpCas9	negative selection	12451975
169237184	169237207	6	-	28162770	OCIAML3	viability	CGGGAGACCAAAGCCTGCCAGGG	THBS2	ENSG00000186340	-0.23852698572577424	[33]	[86]	-2	hSpCas9	negative selection	12451976
169248689	169248712	6	+	28162770	OCIAML3	viability	ACTGCCTCTGGGAGAGACCGGGG	THBS2	ENSG00000186340	-0.7032367100789216	[47]	[88]	-5	hSpCas9	negative selection	12451977
169248557	169248580	6	-	28162770	OCIAML3	viability	GAAGAACGTCACCGTGCAGGTGG	THBS2	ENSG00000186340	1.304845636218937	[95]	[715]	9	hSpCas9	negative selection	12451978
169246199	169246222	6	-	28162770	OCIAML3	viability	AAGGGTTGCCAGCAAGGCCAGGG	THBS2	ENSG00000186340	0.7818592616740028	[41]	[217]	7	hSpCas9	negative selection	12451979
169241879	169241902	6	+	28162770	OCIAML3	viability	GCTGGGGCCCACGTACTCGGTGG	THBS2	ENSG00000186340	0.8322571143779347	[47]	[257]	7	hSpCas9	negative selection	12451980
169241818	169241841	6	-	28162770	OCIAML3	viability	GGAGCTGGGAAACATGGTCCAGG	THBS2	ENSG00000186340	0.5161752774262598	[62]	[271]	5	hSpCas9	negative selection	12451981
169239640	169239663	6	+	28162770	OCIAML3	viability	GGACTGGCGCAGGTTGCAGGCGG	THBS2	ENSG00000186340	1.027480736422107	[64]	[399]	8	hSpCas9	negative selection	12451982
169237331	169237354	6	-	28162770	OCIAML3	viability	GTGTTAGTCCGGCAGGACGGCGG	THBS2	ENSG00000186340	0.9476510761761328	[61]	[360]	7	hSpCas9	negative selection	12451983
169237302	169237325	6	+	28162770	OCIAML3	viability	ATGAAGACCAAGGTGACCAGTGG	THBS2	ENSG00000186340	0.8409294163923855	[53]	[291]	7	hSpCas9	negative selection	12451984