Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7059
• Symbol:THBS3
• Description:thrombospondin 3

DataSource: http://genomecrispr.dkfz.de/#!/results/THBS3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
155207829	155207852	1	+	26472758	Jiyoye	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	0.4632094164202012	[100]	[104]	3	hSpCas9	negative selection	165075
155196092	155196115	1	-	26472758	Jiyoye	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	-1.035534536257525	[192]	[70]	-6	hSpCas9	negative selection	165076
155201524	155201547	1	+	26472758	Jiyoye	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	5.577100382948185	[0]	[35]	9	hSpCas9	negative selection	165077
155201146	155201169	1	-	26472758	Jiyoye	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-0.39559227105607886	[156]	[89]	-3	hSpCas9	negative selection	165078
155200489	155200512	1	-	26472758	Jiyoye	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.36870123369123764	[227]	[221]	2	hSpCas9	negative selection	165079
155200038	155200061	1	-	26472758	Jiyoye	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	0.14591006852513516	[162]	[135]	1	hSpCas9	negative selection	165080
155198574	155198597	1	-	26472758	Jiyoye	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	0.14808816018874238	[72]	[60]	1	hSpCas9	negative selection	165081
155198424	155198447	1	+	26472758	Jiyoye	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-0.34889903560803737	[75]	[44]	-3	hSpCas9	negative selection	165082
155198134	155198157	1	-	26472758	Jiyoye	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.24849011055848447	[344]	[218]	-2	hSpCas9	negative selection	165083
155197489	155197512	1	-	26472758	Jiyoye	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-0.07435752955987723	[147]	[105]	0	hSpCas9	negative selection	165084
155207829	155207852	1	+	26472758	KBM7	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-0.0998805469442311	[409,313]	[167,147]	-1	hSpCas9	negative selection	356193
155196092	155196115	1	-	26472758	KBM7	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	-0.06319932775455478	[323,500]	[178,200]	0	hSpCas9	negative selection	356194
155201524	155201547	1	+	26472758	KBM7	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-0.8117526074645571	[161,132]	[42,35]	-6	hSpCas9	negative selection	356195
155201146	155201169	1	-	26472758	KBM7	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-0.07146080837282559	[639,527]	[183,327]	0	hSpCas9	negative selection	356196
155200489	155200512	1	-	26472758	KBM7	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.5752237738696127	[595,591]	[502,341]	6	hSpCas9	negative selection	356197
155200038	155200061	1	-	26472758	KBM7	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-0.6511650766462891	[1265,769]	[351,250]	-5	hSpCas9	negative selection	356198
155198574	155198597	1	-	26472758	KBM7	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	0.687216695399097	[416,361]	[233,347]	7	hSpCas9	negative selection	356199
155198424	155198447	1	+	26472758	KBM7	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	0.002329873261912141	[374,278]	[96,201]	0	hSpCas9	negative selection	356200
155198134	155198157	1	-	26472758	KBM7	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.14464344443572807	[1552,1672]	[672,708]	-1	hSpCas9	negative selection	356201
155197489	155197512	1	-	26472758	KBM7	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	0.10675618874230298	[477,339]	[175,229]	1	hSpCas9	negative selection	356202
155207829	155207852	1	+	26472758	Raji	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	0.44298656715803836	[167]	[52]	4	hSpCas9	negative selection	547311
155196092	155196115	1	-	26472758	Raji	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	0.3289413052312343	[246]	[71]	3	hSpCas9	negative selection	547312
155201524	155201547	1	+	26472758	Raji	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-2.6205369191896	[52]	[1]	-9	hSpCas9	negative selection	547313
155201146	155201169	1	-	26472758	Raji	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	0.40903923523470065	[171]	[52]	4	hSpCas9	negative selection	547314
155200489	155200512	1	-	26472758	Raji	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	-0.21454455951376283	[319]	[63]	-2	hSpCas9	negative selection	547315
155200038	155200061	1	-	26472758	Raji	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-1.2816587553723	[659]	[62]	-7	hSpCas9	negative selection	547316
155198574	155198597	1	-	26472758	Raji	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	-0.16110530055230254	[158]	[32]	-1	hSpCas9	negative selection	547317
155198424	155198447	1	+	26472758	Raji	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-0.2780475018199209	[208]	[39]	-2	hSpCas9	negative selection	547318
155198134	155198157	1	-	26472758	Raji	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.5549689980185148	[784]	[123]	-4	hSpCas9	negative selection	547319
155197489	155197512	1	-	26472758	Raji	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-0.6999713866840045	[314]	[44]	-5	hSpCas9	negative selection	547320
155207829	155207852	1	+	26472758	K562	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	0.5555310656345904	[240]	[298]	4	hSpCas9	negative selection	738429
155196092	155196115	1	-	26472758	K562	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	1.2575427496663372	[382]	[772]	9	hSpCas9	negative selection	738430
155201524	155201547	1	+	26472758	K562	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	0.2092292992041469	[82]	[80]	1	hSpCas9	negative selection	738431
155201146	155201169	1	-	26472758	K562	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-1.1558972659056312	[519]	[196]	-6	hSpCas9	negative selection	738432
155200489	155200512	1	-	26472758	K562	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	-0.3991613217991012	[652]	[417]	-3	hSpCas9	negative selection	738433
155200038	155200061	1	-	26472758	K562	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-2.143628257734085	[758]	[144]	-7	hSpCas9	negative selection	738434
155198574	155198597	1	-	26472758	K562	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	0.9510334946451808	[268]	[438]	7	hSpCas9	negative selection	738435
155198424	155198447	1	+	26472758	K562	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-0.3358672858452362	[307]	[205]	-2	hSpCas9	negative selection	738436
155198134	155198157	1	-	26472758	K562	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.06768074985280714	[1279]	[1030]	0	hSpCas9	negative selection	738437
155197489	155197512	1	-	26472758	K562	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-0.7526218968530092	[486]	[243]	-4	hSpCas9	negative selection	738438
155202302	155202325	1	-	26627737	DLD1	viability	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.1748178672562341	[718]	[252,108,226]	-2	hSpCas9	negative selection	766342
155202902	155202925	1	+	26627737	DLD1	viability	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.5464260261328044	[1088]	[468,649,394]	5	hSpCas9	negative selection	766343
155203234	155203257	1	+	26627737	DLD1	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.2921108834893891	[331]	[67,159,150]	3	hSpCas9	negative selection	766344
155203499	155203522	1	+	26627737	DLD1	viability	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.4424741710770926	[499]	[237,237,168]	4	hSpCas9	negative selection	766345
155205256	155205279	1	-	26627737	DLD1	viability	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.5234515147498026	[665]	[142,357,385]	5	hSpCas9	negative selection	766346
155207852	155207875	1	-	26627737	DLD1	viability	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	1.4281060251645612	[62]	[22,87,49]	9	hSpCas9	negative selection	766347
155202302	155202325	1	-	26627737	GBM cells	viability after 5 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.3159114379054883	[411]	[163,190]	-5	hSpCas9	negative selection	848657
155202902	155202925	1	+	26627737	GBM cells	viability after 5 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.408176649474989	[625]	[420,469]	6	hSpCas9	negative selection	848658
155203234	155203257	1	+	26627737	GBM cells	viability after 5 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.3046735605765184	[116]	[63,90]	5	hSpCas9	negative selection	848659
155203499	155203522	1	+	26627737	GBM cells	viability after 5 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.2967168367481755	[399]	[274,251]	4	hSpCas9	negative selection	848660
155205256	155205279	1	-	26627737	GBM cells	viability after 5 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.5980774363395074	[347]	[288,275]	8	hSpCas9	negative selection	848661
155207852	155207875	1	-	26627737	GBM cells	viability after 5 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-0.016197227527801283	[98]	[55,48]	0	hSpCas9	negative selection	848662
155202302	155202325	1	-	26627737	GBM cells	viability after 13 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.33421705520585276	[411]	[189,166]	-4	hSpCas9	negative selection	930972
155202902	155202925	1	+	26627737	GBM cells	viability after 13 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.5218648333308069	[625]	[533,449]	6	hSpCas9	negative selection	930973
155203234	155203257	1	+	26627737	GBM cells	viability after 13 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.2556124190411875	[116]	[61,86]	3	hSpCas9	negative selection	930974
155203499	155203522	1	+	26627737	GBM cells	viability after 13 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.32582677088103273	[399]	[319,232]	4	hSpCas9	negative selection	930975
155205256	155205279	1	-	26627737	GBM cells	viability after 13 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.7863250141161042	[347]	[382,278]	8	hSpCas9	negative selection	930976
155207852	155207875	1	-	26627737	GBM cells	viability after 13 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-0.6408830052049526	[98]	[34,33]	-6	hSpCas9	negative selection	930977
155202302	155202325	1	-	26627737	GBM cells	viability after 21 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.5358421098093105	[411]	[156,151]	-5	hSpCas9	negative selection	1013287
155202902	155202925	1	+	26627737	GBM cells	viability after 21 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.33904090512689455	[625]	[460,401]	3	hSpCas9	negative selection	1013288
155203234	155203257	1	+	26627737	GBM cells	viability after 21 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.259271780794715	[116]	[85,66]	2	hSpCas9	negative selection	1013289
155203499	155203522	1	+	26627737	GBM cells	viability after 21 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.596419424839773	[399]	[373,286]	6	hSpCas9	negative selection	1013290
155205256	155205279	1	-	26627737	GBM cells	viability after 21 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.7493659954117022	[347]	[321,313]	7	hSpCas9	negative selection	1013291
155207852	155207875	1	-	26627737	GBM cells	viability after 21 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	0.38541708738036984	[98]	[75,64]	4	hSpCas9	negative selection	1013292
155202302	155202325	1	-	26627737	RPE1	viability after 9 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.4197287599330444	[1022]	[169,328]	-3	hSpCas9	negative selection	1095602
155202902	155202925	1	+	26627737	RPE1	viability after 9 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	-0.18929877416046614	[1847]	[430,605]	-1	hSpCas9	negative selection	1095603
155203234	155203257	1	+	26627737	RPE1	viability after 9 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.7753095638670073	[450]	[228,257]	5	hSpCas9	negative selection	1095604
155203499	155203522	1	+	26627737	RPE1	viability after 9 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.9032725213885863	[1034]	[588,627]	6	hSpCas9	negative selection	1095605
155205256	155205279	1	-	26627737	RPE1	viability after 9 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.25774274008899833	[1489]	[541,577]	1	hSpCas9	negative selection	1095606
155207852	155207875	1	-	26627737	RPE1	viability after 9 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-2.8422106933297697	[521]	[10,37]	-9	hSpCas9	negative selection	1095607
155202302	155202325	1	-	26627737	RPE1	viability after 12 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.28321228777142426	[1022]	[186,266]	-2	hSpCas9	negative selection	1177917
155202902	155202925	1	+	26627737	RPE1	viability after 12 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.42510171212587866	[1847]	[653,679]	3	hSpCas9	negative selection	1177918
155203234	155203257	1	+	26627737	RPE1	viability after 12 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.46800612722974605	[450]	[136,199]	3	hSpCas9	negative selection	1177919
155203499	155203522	1	+	26627737	RPE1	viability after 12 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.8421873969822343	[1034]	[481,515]	5	hSpCas9	negative selection	1177920
155205256	155205279	1	-	26627737	RPE1	viability after 12 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.6312721627555778	[1489]	[553,689]	4	hSpCas9	negative selection	1177921
155207852	155207875	1	-	26627737	RPE1	viability after 12 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-4.843225086955815	[521]	[0,8]	-9	hSpCas9	negative selection	1177922
155202302	155202325	1	-	26627737	RPE1	viability after 15 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.2552563787986518	[1022]	[272,212]	-2	hSpCas9	negative selection	1260232
155202902	155202925	1	+	26627737	RPE1	viability after 15 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.25197704923124786	[1847]	[536,704]	1	hSpCas9	negative selection	1260233
155203234	155203257	1	+	26627737	RPE1	viability after 15 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.6128486022471041	[450]	[104,281]	4	hSpCas9	negative selection	1260234
155203499	155203522	1	+	26627737	RPE1	viability after 15 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.7935721070944391	[1034]	[507,506]	5	hSpCas9	negative selection	1260235
155205256	155205279	1	-	26627737	RPE1	viability after 15 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.3427350358067415	[1489]	[364,697]	2	hSpCas9	negative selection	1260236
155207852	155207875	1	-	26627737	RPE1	viability after 15 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-4.183488047348274	[521]	[0,14]	-9	hSpCas9	negative selection	1260237
155202302	155202325	1	-	26627737	RPE1	viability after 18 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	0.08886516603861222	[1022]	[296,289]	0	hSpCas9	negative selection	1342547
155202902	155202925	1	+	26627737	RPE1	viability after 18 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.42991101341988047	[1847]	[579,769]	2	hSpCas9	negative selection	1342548
155203234	155203257	1	+	26627737	RPE1	viability after 18 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.3554546801172322	[450]	[161,148]	2	hSpCas9	negative selection	1342549
155203499	155203522	1	+	26627737	RPE1	viability after 18 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.5704131984779112	[1034]	[305,530]	3	hSpCas9	negative selection	1342550
155205256	155205279	1	-	26627737	RPE1	viability after 18 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.45403335633772224	[1489]	[370,742]	3	hSpCas9	negative selection	1342551
155207852	155207875	1	-	26627737	RPE1	viability after 18 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-3.65905131995203	[521]	[0,21]	-9	hSpCas9	negative selection	1342552
155202302	155202325	1	-	26627737	HeLa	viability after 8 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.27202099978331507	[783]	[204,379,247]	-3	hSpCas9	negative selection	1424862
155202902	155202925	1	+	26627737	HeLa	viability after 8 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	1.9455217246908243	[321]	[772,499,406]	9	hSpCas9	negative selection	1424863
155203234	155203257	1	+	26627737	HeLa	viability after 8 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.9088796876461431	[103]	[97,92,67]	7	hSpCas9	negative selection	1424864
155203499	155203522	1	+	26627737	HeLa	viability after 8 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.9340231557397847	[484]	[511,294,424]	7	hSpCas9	negative selection	1424865
155205256	155205279	1	-	26627737	HeLa	viability after 8 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.3361444566539804	[635]	[345,435,270]	3	hSpCas9	negative selection	1424866
155207852	155207875	1	-	26627737	HeLa	viability after 8 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-0.38609874173884395	[141]	[159,8,0]	-4	hSpCas9	negative selection	1424867
155202302	155202325	1	-	26627737	HeLa	viability after 12 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.24800685466254446	[783]	[121,386,292]	-2	hSpCas9	negative selection	1507177
155202902	155202925	1	+	26627737	HeLa	viability after 12 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	1.9033789589348902	[321]	[624,479,393]	9	hSpCas9	negative selection	1507178
155203234	155203257	1	+	26627737	HeLa	viability after 12 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.5173153865234241	[103]	[0,3,86]	-4	hSpCas9	negative selection	1507179
155203499	155203522	1	+	26627737	HeLa	viability after 12 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.5964758279174738	[484]	[300,256,355]	5	hSpCas9	negative selection	1507180
155205256	155205279	1	-	26627737	HeLa	viability after 12 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	-0.17529197142310526	[635]	[309,218,172]	-1	hSpCas9	negative selection	1507181
155207852	155207875	1	-	26627737	HeLa	viability after 12 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-2.847991359720651	[141]	[2,10,9]	-9	hSpCas9	negative selection	1507182
155202302	155202325	1	-	26627737	HeLa	viability after 15 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.4279720862313584	[783]	[189,119,415]	-4	hSpCas9	negative selection	1589492
155202902	155202925	1	+	26627737	HeLa	viability after 15 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	2.113755433133024	[321]	[511,584,608]	9	hSpCas9	negative selection	1589493
155203234	155203257	1	+	26627737	HeLa	viability after 15 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.19039474052180583	[103]	[0,70,39]	-2	hSpCas9	negative selection	1589494
155203499	155203522	1	+	26627737	HeLa	viability after 15 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.5585672989111192	[484]	[209,389,271]	4	hSpCas9	negative selection	1589495
155205256	155205279	1	-	26627737	HeLa	viability after 15 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.10475396063244624	[635]	[247,159,439]	0	hSpCas9	negative selection	1589496
155207852	155207875	1	-	26627737	HeLa	viability after 15 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	0.888959418134039	[141]	[143,101,71]	6	hSpCas9	negative selection	1589497
155202302	155202325	1	-	26627737	HeLa	viability after 18 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.43793028537185597	[783]	[122,100,415]	-4	hSpCas9	negative selection	1671807
155202902	155202925	1	+	26627737	HeLa	viability after 18 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	2.1274795277865244	[321]	[351,486,608]	9	hSpCas9	negative selection	1671808
155203234	155203257	1	+	26627737	HeLa	viability after 18 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.18049043833125578	[103]	[0,58,39]	-1	hSpCas9	negative selection	1671809
155203499	155203522	1	+	26627737	HeLa	viability after 18 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.5430608157970289	[484]	[133,323,271]	4	hSpCas9	negative selection	1671810
155205256	155205279	1	-	26627737	HeLa	viability after 18 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.06371783607946613	[635]	[157,123,439]	0	hSpCas9	negative selection	1671811
155207852	155207875	1	-	26627737	HeLa	viability after 18 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	0.9110551638380289	[141]	[100,82,71]	7	hSpCas9	negative selection	1671812
155202302	155202325	1	-	26627737	HCT116	viability after 6 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.8376277605143225	[1259]	[144,91]	-5	hSpCas9	negative selection	1754122
155202902	155202925	1	+	26627737	HCT116	viability after 6 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.7563959096593802	[1521]	[195,518]	4	hSpCas9	negative selection	1754123
155203234	155203257	1	+	26627737	HCT116	viability after 6 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.8262297974996271	[431]	[85,11]	-5	hSpCas9	negative selection	1754124
155203499	155203522	1	+	26627737	HCT116	viability after 6 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.9241376523575185	[1124]	[624,175]	5	hSpCas9	negative selection	1754125
155205256	155205279	1	-	26627737	HCT116	viability after 6 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	-0.013355367649655947	[1007]	[127,172]	0	hSpCas9	negative selection	1754126
155207852	155207875	1	-	26627737	HCT116	viability after 6 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-0.7068941839072842	[170]	[0,24]	-4	hSpCas9	negative selection	1754127
155202302	155202325	1	-	26627737	HCT116	viability after 8 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	0.25889926013485454	[549]	[368,271,445]	3	hSpCas9	negative selection	1836437
155202902	155202925	1	+	26627737	HCT116	viability after 8 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	1.0718530535060422	[579]	[734,475,803]	8	hSpCas9	negative selection	1836438
155203234	155203257	1	+	26627737	HCT116	viability after 8 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.47792088273154243	[83]	[93,41,57]	5	hSpCas9	negative selection	1836439
155203499	155203522	1	+	26627737	HCT116	viability after 8 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	-0.3510111613072191	[787]	[340,313,365]	-4	hSpCas9	negative selection	1836440
155205256	155205279	1	-	26627737	HCT116	viability after 8 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.2205563838717678	[575]	[453,207,447]	2	hSpCas9	negative selection	1836441
155207852	155207875	1	-	26627737	HCT116	viability after 8 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-1.6937017151613794	[265]	[39,63,31]	-9	hSpCas9	negative selection	1836442
155202302	155202325	1	-	26627737	HCT116	viability after 9 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.3508090641872217	[1259]	[255,269]	-2	hSpCas9	negative selection	1918752
155202902	155202925	1	+	26627737	HCT116	viability after 9 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.32419713722081855	[1521]	[524,495]	2	hSpCas9	negative selection	1918753
155203234	155203257	1	+	26627737	HCT116	viability after 9 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-1.4882304808714242	[431]	[39,41]	-8	hSpCas9	negative selection	1918754
155203499	155203522	1	+	26627737	HCT116	viability after 9 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	-0.40302630930190575	[1124]	[172,269]	-3	hSpCas9	negative selection	1918755
155205256	155205279	1	-	26627737	HCT116	viability after 9 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	-0.39808193557853516	[1007]	[363,77]	-3	hSpCas9	negative selection	1918756
155207852	155207875	1	-	26627737	HCT116	viability after 9 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-1.711088813738125	[170]	[23,5]	-8	hSpCas9	negative selection	1918757
155202302	155202325	1	-	26627737	HCT116	viability after 12 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	0.4720792276984509	[549]	[479,324,388]	4	hSpCas9	negative selection	2001067
155202902	155202925	1	+	26627737	HCT116	viability after 12 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.8890361903087929	[579]	[350,803,562]	7	hSpCas9	negative selection	2001068
155203234	155203257	1	+	26627737	HCT116	viability after 12 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.08167615246663229	[83]	[16,69,40]	-1	hSpCas9	negative selection	2001069
155203499	155203522	1	+	26627737	HCT116	viability after 12 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	-0.722048485101659	[787]	[262,287,201]	-7	hSpCas9	negative selection	2001070
155205256	155205279	1	-	26627737	HCT116	viability after 12 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	-0.1906547317347469	[575]	[304,256,229]	-2	hSpCas9	negative selection	2001071
155207852	155207875	1	-	26627737	HCT116	viability after 12 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-2.4556758182551293	[265]	[30,26,17]	-9	hSpCas9	negative selection	2001072
155202302	155202325	1	-	26627737	HCT116	viability after 15 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	0.22817616663959694	[549]	[591,259,285]	2	hSpCas9	negative selection	2083382
155202902	155202925	1	+	26627737	HCT116	viability after 15 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.9886391898172653	[579]	[834,586,582]	8	hSpCas9	negative selection	2083383
155203234	155203257	1	+	26627737	HCT116	viability after 15 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.2837383091598229	[83]	[104,33,42]	3	hSpCas9	negative selection	2083384
155203499	155203522	1	+	26627737	HCT116	viability after 15 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	-0.5360518569661955	[787]	[388,272,283]	-5	hSpCas9	negative selection	2083385
155205256	155205279	1	-	26627737	HCT116	viability after 15 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.39485633560274647	[575]	[565,340,413]	4	hSpCas9	negative selection	2083386
155207852	155207875	1	-	26627737	HCT116	viability after 15 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-2.7903851024929605	[265]	[35,14,16]	-9	hSpCas9	negative selection	2083387
155202302	155202325	1	-	26627737	HCT116	viability after 18 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	0.3054990405861422	[549]	[490,191,310]	2	hSpCas9	negative selection	2165697
155202902	155202925	1	+	26627737	HCT116	viability after 18 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.6207486034828156	[579]	[382,420,492]	5	hSpCas9	negative selection	2165698
155203234	155203257	1	+	26627737	HCT116	viability after 18 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.36287975282597906	[83]	[39,62,52]	3	hSpCas9	negative selection	2165699
155203499	155203522	1	+	26627737	HCT116	viability after 18 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	-0.5453390134853681	[787]	[274,187,327]	-5	hSpCas9	negative selection	2165700
155205256	155205279	1	-	26627737	HCT116	viability after 18 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.4402810909216853	[575]	[379,372,380]	4	hSpCas9	negative selection	2165701
155207852	155207875	1	-	26627737	HCT116	viability after 18 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-1.015771472618363	[265]	[87,68,31]	-7	hSpCas9	negative selection	2165702
155199365	155199388	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCCACTGTACTCCAGCCTGGG	THBS3	ENSG00000169231	-1.9834711090057278	[190,159]	[9,8]	-9	dCas9-VP64	positive selection	2385601
155208579	155208602	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCCACAGTGTTCCACAGTCTGG	THBS3	ENSG00000169231	3.181482394700691	[144,105]	[296,201]	8	dCas9-VP64	positive selection	2430481
155208603	155208626	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTAGCGGACGGGCCGTGACCCGG	THBS3	ENSG00000169231	-2.1566451949649816	[94,88]	[2,5]	-9	dCas9-VP64	positive selection	2430482
155208552	155208575	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGCTCCTCGCCTGTACCCCTGG	THBS3	ENSG00000169231	1.3175329209416053	[39,6]	[4,20]	5	dCas9-VP64	positive selection	2430483
155208056	155208079	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGATTCTTTCCCAGTGCCCCTGG	THBS3	ENSG00000169231	1.7155678071241756	[16,58]	[8,46]	6	dCas9-VP64	positive selection	2441144
155208100	155208123	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGGAGGATCATTAGGGAGAGG	THBS3	ENSG00000169231	0.5026442706471723	[22,208]	[3,71]	2	dCas9-VP64	positive selection	2441145
155208077	155208100	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TAGAAAGCAGGGAGGCCTCCAGG	THBS3	ENSG00000169231	-1.291413858790617	[6,34]	[0,1]	-7	dCas9-VP64	positive selection	2441146
155199365	155199388	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCCACTGTACTCCAGCCTGGG	THBS3	ENSG00000169231	-0.49457347436203747	[225,196]	[51,45]	-5	dCas9-VP64	positive selection	2480856
155208579	155208602	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCCACAGTGTTCCACAGTCTGG	THBS3	ENSG00000169231	0.2811645856881534	[48,168]	[24,58]	2	dCas9-VP64	positive selection	2525736
155208603	155208626	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTAGCGGACGGGCCGTGACCCGG	THBS3	ENSG00000169231	-0.613722860241775	[217,5]	[19,27]	-6	dCas9-VP64	positive selection	2525737
155208552	155208575	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGCTCCTCGCCTGTACCCCTGG	THBS3	ENSG00000169231	-0.6018832021560276	[80,31]	[16,6]	-6	dCas9-VP64	positive selection	2525738
155208056	155208079	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGATTCTTTCCCAGTGCCCCTGG	THBS3	ENSG00000169231	1.7821778491784819	[31,254]	[284,40]	8	dCas9-VP64	positive selection	2536399
155208100	155208123	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGGAGGATCATTAGGGAGAGG	THBS3	ENSG00000169231	1.5428696260863104	[411,61]	[427,42]	8	dCas9-VP64	positive selection	2536400
155208077	155208100	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TAGAAAGCAGGGAGGCCTCCAGG	THBS3	ENSG00000169231	-0.5452524664445655	[42,51]	[12,7]	-5	dCas9-VP64	positive selection	2536401
155202896	155202919	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCCATGCAGTCCACACCTCGG	THBS3	ENSG00000169231	0.4551500596559007	[4,3]	[4,5]	8	hSpCas9	positive selection	3026624
155207830	155207853	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-0.4797578831619542	[2,2]	[1,0]	-6	hSpCas9	positive selection	3026625
155201525	155201548	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	0.09855743937428646	[4,3]	[3,3]	2	hSpCas9	positive selection	3026626
155207797	155207820	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGCCAGTCAGGATCTGCAGGG	THBS3	ENSG00000169231	0.5755091038915194	[4,4]	[4,7]	9	hSpCas9	positive selection	3026627
155202896	155202919	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCCATGCAGTCCACACCTCGG	THBS3	ENSG00000169231	-0.005007912003987425	[4,4]	[4,1]	0	hSpCas9	positive selection	3094482
155207830	155207853	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-0.8572387491758929	[2,2]	[0,0]	-9	hSpCas9	positive selection	3094483
155201525	155201548	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	0.027162408937979804	[4,4]	[3,2]	0	hSpCas9	positive selection	3094484
155207797	155207820	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGCCAGTCAGGATCTGCAGGG	THBS3	ENSG00000169231	0.1421961224412589	[4,4]	[5,2]	2	hSpCas9	positive selection	3094485
155203101	155203124		-	24336571	A375	resistance to PLX after 7 days	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.016192774929990716	[22,26]	[21,26]	0	hSpCas9	positive selection	3150132
155203087	155203110		+	24336571	A375	resistance to PLX after 7 days	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.19139124875567837	[1,4]	[2,2]	-6	hSpCas9	positive selection	3150133
155203222	155203245		-	24336571	A375	resistance to PLX after 7 days	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.12357183884542647	[10,9]	[11,10]	4	hSpCas9	positive selection	3150134
155203234	155203257		+	24336571	A375	resistance to PLX after 7 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.009049282968534023	[39,35]	[40,34]	0	hSpCas9	positive selection	3150135
155203101	155203124		-	24336571	A375	resistance to PLX after 14 days	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.5460597798582114	[29,20]	[9,4]	-6	hSpCas9	positive selection	3207925
155203087	155203110		+	24336571	A375	resistance to PLX after 14 days	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.8767028849866658	[2,2]	[1,1]	7	hSpCas9	positive selection	3207926
155203222	155203245		-	24336571	A375	resistance to PLX after 14 days	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.4687635383808026	[5,10]	[4,4]	4	hSpCas9	positive selection	3207927
155203234	155203257		+	24336571	A375	resistance to PLX after 14 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.4941516344691317	[32,36]	[12,9]	-6	hSpCas9	positive selection	3207928
155203101	155203124		-	24336571	A375	viability after 7 days	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.05911156326653566	[24]	[22,26]	0	hSpCas9	negative selection	3265718
155203087	155203110		+	24336571	A375	viability after 7 days	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.5503099101456157	[1]	[1,4]	8	hSpCas9	negative selection	3265719
155203222	155203245		-	24336571	A375	viability after 7 days	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.2993064050690071	[13]	[10,9]	-4	hSpCas9	negative selection	3265720
155203234	155203257		+	24336571	A375	viability after 7 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.5036899263066783	[56]	[39,35]	-6	hSpCas9	negative selection	3265721
155203101	155203124		-	24336571	A375	viability after 14 days	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.13464204827325	[24]	[29,20]	1	hSpCas9	negative selection	3323511
155203087	155203110		+	24336571	A375	viability after 14 days	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.23940985623879207	[1]	[2,2]	3	hSpCas9	negative selection	3323512
155203222	155203245		-	24336571	A375	viability after 14 days	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.5606809508250007	[13]	[5,10]	-6	hSpCas9	negative selection	3323513
155203234	155203257		+	24336571	A375	viability after 14 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.6187458410872162	[56]	[32,36]	-6	hSpCas9	negative selection	3323514
155203101	155203124	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	1.1075790919411528	[212,212]	[2,2]	5	hSpCas9	positive selection	3397057
155203234	155203257	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.42566837223584786	[410,410]	[1,1]	-3	hSpCas9	positive selection	3397058
155202912	155202935	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.7760967900916153	[261,261]	[0,0]	-5	hSpCas9	positive selection	3397059
155202895	155202918	1	+	26780180	HT29	viability (Avana library 4 designs)	CTTCCATGCAGTCCACACCTCGG	THBS3	ENSG00000169231	0.804120081423784	[]	[]	3	hSpCas9	negative selection	3465363
155207829	155207852	1	+	26780180	HT29	viability (Avana library 4 designs)	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	2.56677491350763	[]	[]	8	hSpCas9	negative selection	3465364
155201524	155201547	1	+	26780180	HT29	viability (Avana library 4 designs)	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	0.199380206619829	[]	[]	0	hSpCas9	negative selection	3465365
155207797	155207820	1	-	26780180	HT29	viability (Avana library 4 designs)	TCTGCCAGTCAGGATCTGCAGGG	THBS3	ENSG00000169231	0.698700643344168	[]	[]	2	hSpCas9	negative selection	3465366
155201524	155201547	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	1.30666899365561	[]	[]	1	hSpCas9	negative selection	3568521
155207797	155207820	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGCCAGTCAGGATCTGCAGGG	THBS3	ENSG00000169231	1.8208406705991	[]	[]	2	hSpCas9	negative selection	3568522
155207829	155207852	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-0.657929031821301	[]	[]	-1	hSpCas9	negative selection	3568523
155202895	155202918	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCCATGCAGTCCACACCTCGG	THBS3	ENSG00000169231	0.757253003401108	[]	[]	1	hSpCas9	negative selection	3568524
155206199	155206222	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGTAGGCAAGATCAACAAAGG	THBS3	ENSG00000169231	-4.09228478851436	[]	[]	-5	hSpCas9	negative selection	3568525
155201514	155201537	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCCTGGGCAACCAGAGCCAGGG	THBS3	ENSG00000169231	0.371773392888313	[]	[]	0	hSpCas9	negative selection	3568526
155201524	155201547	1	+	26780180	A375	viability (Avana lentiGuide)	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	2.96064363272967	[]	[]	3	hSpCas9	negative selection	3677180
155207797	155207820	1	-	26780180	A375	viability (Avana lentiGuide)	TCTGCCAGTCAGGATCTGCAGGG	THBS3	ENSG00000169231	-0.935624116686111	[]	[]	-1	hSpCas9	negative selection	3677181
155207829	155207852	1	+	26780180	A375	viability (Avana lentiGuide)	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	12.3879426586552	[]	[]	7	hSpCas9	negative selection	3677182
155202895	155202918	1	+	26780180	A375	viability (Avana lentiGuide)	CTTCCATGCAGTCCACACCTCGG	THBS3	ENSG00000169231	4.19323532788963	[]	[]	4	hSpCas9	negative selection	3677183
155206199	155206222	1	-	26780180	A375	viability (Avana lentiGuide)	GTTGTAGGCAAGATCAACAAAGG	THBS3	ENSG00000169231	-0.129765496975632	[]	[]	0	hSpCas9	negative selection	3677184
155201514	155201537	1	-	26780180	A375	viability (Avana lentiGuide)	TTCCTGGGCAACCAGAGCCAGGG	THBS3	ENSG00000169231	8.28273157017541	[]	[]	6	hSpCas9	negative selection	3677185
155201524	155201547	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-0.39764017868956103	[5]	[4,2]	-5	hSpCas9	positive selection	3785787
155207797	155207820	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGCCAGTCAGGATCTGCAGGG	THBS3	ENSG00000169231	0.0006481966693772101	[6]	[6,5]	0	hSpCas9	positive selection	3785788
155207829	155207852	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-0.6418096583176678	[4]	[2,2]	-7	hSpCas9	positive selection	3785789
155202895	155202918	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCCATGCAGTCCACACCTCGG	THBS3	ENSG00000169231	-0.17213329884550754	[4]	[4,3]	-3	hSpCas9	positive selection	3785790
155206199	155206222	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGTAGGCAAGATCAACAAAGG	THBS3	ENSG00000169231	-0.4970205068658738	[5]	[3,3]	-6	hSpCas9	positive selection	3785791
155201514	155201537	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCCTGGGCAACCAGAGCCAGGG	THBS3	ENSG00000169231	-0.046885094391569244	[5]	[5,4]	-1	hSpCas9	positive selection	3785792
155201524	155201547	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	0.1472770233997835	[6]	[5,5]	3	hSpCas9	positive selection	3894394
155207797	155207820	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGCCAGTCAGGATCTGCAGGG	THBS3	ENSG00000169231	-0.029645333400084434	[6]	[4,5]	0	hSpCas9	positive selection	3894395
155207829	155207852	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-1.6351470584564125	[4]	[0,0]	-9	hSpCas9	positive selection	3894396
155202895	155202918	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCCATGCAGTCCACACCTCGG	THBS3	ENSG00000169231	0.008352451496701468	[5]	[4,5]	0	hSpCas9	positive selection	3894397
155206199	155206222	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGTAGGCAAGATCAACAAAGG	THBS3	ENSG00000169231	0.3168227597517741	[4]	[4,5]	8	hSpCas9	positive selection	3894398
155201514	155201537	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCCTGGGCAACCAGAGCCAGGG	THBS3	ENSG00000169231	-0.8610243724628792	[4]	[2,1]	-8	hSpCas9	positive selection	3894399
155202912	155202935	1	-	26780180	A375	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	1.71152775201771	[]	[]	9	hSpCas9	negative selection	4003745
155202879	155202902	1	-	26780180	A375	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	1.54503213894134	[]	[]	8	hSpCas9	negative selection	4003746
155203101	155203124	1	-	26780180	A375	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	1.16371363802632	[]	[]	6	hSpCas9	negative selection	4003747
155203087	155203110	1	+	26780180	A375	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	1.76396489219972	[]	[]	9	hSpCas9	negative selection	4003748
155203222	155203245	1	-	26780180	A375	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	1.67842945731844	[]	[]	9	hSpCas9	negative selection	4003749
155203234	155203257	1	+	26780180	A375	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	1.83479553367519	[]	[]	9	hSpCas9	negative selection	4003750
155202912	155202935	1	-	26780180	HT29	viability (GeCKOv2 library)	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.450752032565594	[]	[]	1	hSpCas9	negative selection	4111711
155202879	155202902	1	-	26780180	HT29	viability (GeCKOv2 library)	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	1.76569688106878	[]	[]	8	hSpCas9	negative selection	4111712
155203101	155203124	1	-	26780180	HT29	viability (GeCKOv2 library)	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	1.05166130803408	[]	[]	5	hSpCas9	negative selection	4111713
155203087	155203110	1	+	26780180	HT29	viability (GeCKOv2 library)	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	1.1787600169059	[]	[]	6	hSpCas9	negative selection	4111714
155203222	155203245	1	-	26780180	HT29	viability (GeCKOv2 library)	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	1.78429820855852	[]	[]	8	hSpCas9	negative selection	4111715
155203234	155203257	1	+	26780180	HT29	viability (GeCKOv2 library)	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.989766185385523	[]	[]	4	hSpCas9	negative selection	4111716
155203101	155203124	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.3275996676175526	[4]	[4,2]	7	hSpCas9	positive selection	4176511
155203087	155203110	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.4906535877074895	[4]	[2,0]	-8	hSpCas9	positive selection	4176512
155203222	155203245	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.19637994621750826	[3]	[1,2]	-5	hSpCas9	positive selection	4176513
155203234	155203257	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.07588283824666803	[5]	[3,3]	-2	hSpCas9	positive selection	4176514
155203101	155203124	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.236289681791778	[5]	[1,3,2,0]	-3	hSpCas9	positive selection	4240533
155203087	155203110	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.9334057040535989	[4]	[3,2,1,4]	6	hSpCas9	positive selection	4240534
155203222	155203245	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.41844965823305125	[2]	[1,1,4,0]	3	hSpCas9	positive selection	4240535
155203234	155203257	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.657246183346633	[5]	[3,2,5,3]	4	hSpCas9	positive selection	4240536
155203222	155203245	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.27390360019761306	[3]	[2,1]	-5	hSpCas9	positive selection	4302949
155202879	155202902	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.23574282728306895	[3]	[2,1]	-5	hSpCas9	positive selection	4302950
155203087	155203110	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.008722479985404409	[3]	[2,1]	0	hSpCas9	positive selection	4302951
155203101	155203124	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.017059183377600255	[3]	[2,1]	0	hSpCas9	positive selection	4367203
155203234	155203257	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.05546526996123902	[4]	[3,3]	1	hSpCas9	positive selection	4367204
155202912	155202935	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.5359501251588489	[3]	[3,3]	9	hSpCas9	positive selection	4367205
155201195	155201217	1	-	27760321	OCIAML3	viability	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	-0.7167810145709338	[523,462]	[223,247]	-6	hSpCas9	negative selection	4446752
155202003	155202025	1	-	27760321	OCIAML3	viability	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	-0.8004483438359221	[406,344]	[136,208]	-6	hSpCas9	negative selection	4446753
155203102	155203124	1	+	27760321	OCIAML3	viability	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	-0.8929416909676757	[257,180]	[80,104]	-7	hSpCas9	negative selection	4446754
155203222	155203244	1	-	27760321	OCIAML3	viability	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-1.3519689812687898	[397,323]	[106,113]	-8	hSpCas9	negative selection	4446755
155206243	155206265	1	+	27760321	OCIAML3	viability	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	-0.7123864934955083	[244,222]	[95,131]	-6	hSpCas9	negative selection	4446756
155201195	155201217	1	-	27760321	OCIAML2	viability	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	0.32349196646859346	[523,462]	[420,600]	4	hSpCas9	negative selection	4530215
155202003	155202025	1	-	27760321	OCIAML2	viability	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	-0.04690088918582441	[406,344]	[232,372]	0	hSpCas9	negative selection	4530216
155203102	155203124	1	+	27760321	OCIAML2	viability	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	0.5138937433176372	[257,180]	[185,335]	7	hSpCas9	negative selection	4530217
155203222	155203244	1	-	27760321	OCIAML2	viability	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.20224021834866962	[397,323]	[236,272]	-3	hSpCas9	negative selection	4530218
155206243	155206265	1	+	27760321	OCIAML2	viability	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	0.8406659771141893	[244,222]	[261,439]	9	hSpCas9	negative selection	4530219
155201195	155201217	1	-	27760321	MV411	viability	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	-0.22381946416907916	[523,462]	[233,344]	-2	hSpCas9	negative selection	4613678
155202003	155202025	1	-	27760321	MV411	viability	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	1.4616882206380244	[406,344]	[951,273]	9	hSpCas9	negative selection	4613679
155203102	155203124	1	+	27760321	MV411	viability	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	0.7425407694603834	[257,180]	[64,501]	5	hSpCas9	negative selection	4613680
155203222	155203244	1	-	27760321	MV411	viability	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.008581406541330883	[397,323]	[257,208]	0	hSpCas9	negative selection	4613681
155206243	155206265	1	+	27760321	MV411	viability	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	0.6247901651309729	[244,222]	[203,288]	4	hSpCas9	negative selection	4613682
155201195	155201217	1	-	27760321	HL60	viability	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	-0.012587033762841204	[523,462]	[395,401]	0	hSpCas9	negative selection	4697141
155202003	155202025	1	-	27760321	HL60	viability	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	0.12817993311100712	[406,344]	[334,333]	1	hSpCas9	negative selection	4697142
155203102	155203124	1	+	27760321	HL60	viability	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	0.8179633405967476	[257,180]	[331,291]	8	hSpCas9	negative selection	4697143
155203222	155203244	1	-	27760321	HL60	viability	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-1.8670235038599898	[397,323]	[77,82]	-9	hSpCas9	negative selection	4697144
155206243	155206265	1	+	27760321	HL60	viability	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	0.5225066064050494	[244,222]	[221,329]	6	hSpCas9	negative selection	4697145
155201195	155201217	1	-	27760321	HT1080	viability	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	-0.7546981115132526	[462,360]	[123,67]	-3	hSpCas9	negative selection	4780604
155202003	155202025	1	-	27760321	HT1080	viability	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	-1.3635424561016831	[344,268]	[26,69]	-5	hSpCas9	negative selection	4780605
155203102	155203124	1	+	27760321	HT1080	viability	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	-1.417970359653658	[180,140]	[23,23]	-5	hSpCas9	negative selection	4780606
155203222	155203244	1	-	27760321	HT1080	viability	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-1.712503659273243	[323,252]	[25,44]	-6	hSpCas9	negative selection	4780607
155206243	155206265	1	+	27760321	HT1080	viability	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	0.7649790836352384	[222,173]	[57,217]	4	hSpCas9	negative selection	4780608
155201195	155201217	1	-	27760321	HT29	viability after 7 days	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	-0.28363927634926944	[462,360]	[716,256,372]	-4	hSpCas9	negative selection	4864067
155202003	155202025	1	-	27760321	HT29	viability after 7 days	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	-0.49859731941850405	[344,268]	[364,240,244]	-6	hSpCas9	negative selection	4864068
155203102	155203124	1	+	27760321	HT29	viability after 7 days	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	-0.5923025506762443	[180,140]	[122,97,186]	-7	hSpCas9	negative selection	4864069
155203222	155203244	1	-	27760321	HT29	viability after 7 days	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.8161595825176685	[323,252]	[328,248,74]	-8	hSpCas9	negative selection	4864070
155206243	155206265	1	+	27760321	HT29	viability after 7 days	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	-0.3364873758544288	[222,173]	[253,110,246]	-5	hSpCas9	negative selection	4864071
155201195	155201217	1	-	27760321	HT29	viability after 25 days	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	0.2858297632830651	[462,360]	[704,457,546]	3	hSpCas9	negative selection	4947530
155202003	155202025	1	-	27760321	HT29	viability after 25 days	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	0.00033693584592126014	[344,268]	[392,361,287]	0	hSpCas9	negative selection	4947531
155203102	155203124	1	+	27760321	HT29	viability after 25 days	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	0.36987164941550343	[180,140]	[197,342,166]	4	hSpCas9	negative selection	4947532
155203222	155203244	1	-	27760321	HT29	viability after 25 days	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.1395574461171078	[323,252]	[294,197,416]	-1	hSpCas9	negative selection	4947533
155206243	155206265	1	+	27760321	HT29	viability after 25 days	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	-0.28794966530637056	[222,173]	[155,199,204]	-3	hSpCas9	negative selection	4947534
155201195	155201217	1	-	27760321	HT29	viability after 22 days	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	0.23826069601674524	[462,360]	[605,530,546]	2	hSpCas9	negative selection	5030993
155202003	155202025	1	-	27760321	HT29	viability after 22 days	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	0.09057261100372174	[344,268]	[369,368,394]	0	hSpCas9	negative selection	5030994
155203102	155203124	1	+	27760321	HT29	viability after 22 days	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	0.478078968686676	[180,140]	[417,237,115]	5	hSpCas9	negative selection	5030995
155203222	155203244	1	-	27760321	HT29	viability after 22 days	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.40718025677280445	[323,252]	[276,208,267]	-4	hSpCas9	negative selection	5030996
155206243	155206265	1	+	27760321	HT29	viability after 22 days	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	-0.4419022066331876	[222,173]	[133,175,197]	-4	hSpCas9	negative selection	5030997
155201195	155201217	1	-	27760321	HT29	viability after 19 days	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	0.5024232104627793	[462,360]	[1122,591,346]	5	hSpCas9	negative selection	5114456
155202003	155202025	1	-	27760321	HT29	viability after 19 days	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	0.15545283651440678	[344,268]	[546,514,136]	1	hSpCas9	negative selection	5114457
155203102	155203124	1	+	27760321	HT29	viability after 19 days	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	0.03293273468844915	[180,140]	[238,269,65]	0	hSpCas9	negative selection	5114458
155203222	155203244	1	-	27760321	HT29	viability after 19 days	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.14599460473342823	[323,252]	[404,132,364]	-1	hSpCas9	negative selection	5114459
155206243	155206265	1	+	27760321	HT29	viability after 19 days	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	-0.8062207823424262	[222,173]	[106,176,103]	-6	hSpCas9	negative selection	5114460
155201195	155201217	1	-	27760321	HT29	viability after 16 days	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	0.06289068576214438	[462,360]	[661,264,539]	0	hSpCas9	negative selection	5197919
155202003	155202025	1	-	27760321	HT29	viability after 16 days	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	-0.3371958745534669	[344,268]	[420,181,228]	-4	hSpCas9	negative selection	5197920
155203102	155203124	1	+	27760321	HT29	viability after 16 days	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	-0.3350533341160733	[180,140]	[94,96,232]	-4	hSpCas9	negative selection	5197921
155203222	155203244	1	-	27760321	HT29	viability after 16 days	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.4563983896129089	[323,252]	[168,213,316]	-4	hSpCas9	negative selection	5197922
155206243	155206265	1	+	27760321	HT29	viability after 16 days	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	0.32488116580328674	[222,173]	[126,284,407]	3	hSpCas9	negative selection	5197923
155201195	155201217	1	-	27760321	HT29	viability after 13 days	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	0.16682711766698097	[462,360]	[715,457,440]	2	hSpCas9	negative selection	5281382
155202003	155202025	1	-	27760321	HT29	viability after 13 days	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	0.17831194971890654	[344,268]	[403,369,432]	2	hSpCas9	negative selection	5281383
155203102	155203124	1	+	27760321	HT29	viability after 13 days	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	-0.28762292513541676	[180,140]	[139,165,152]	-4	hSpCas9	negative selection	5281384
155203222	155203244	1	-	27760321	HT29	viability after 13 days	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.8878928600488601	[323,252]	[239,130,171]	-7	hSpCas9	negative selection	5281385
155206243	155206265	1	+	27760321	HT29	viability after 13 days	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	-0.3034390392265961	[222,173]	[154,186,215]	-4	hSpCas9	negative selection	5281386
155201195	155201217	1	-	27760321	HT29	viability after 10 days	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	-0.3630399731918601	[462,360]	[417,436,346]	-5	hSpCas9	negative selection	5364845
155202003	155202025	1	-	27760321	HT29	viability after 10 days	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	-0.06224608631535647	[344,268]	[447,225,421]	-1	hSpCas9	negative selection	5364846
155203102	155203124	1	+	27760321	HT29	viability after 10 days	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	-0.1653807488556691	[180,140]	[150,218,168]	-2	hSpCas9	negative selection	5364847
155203222	155203244	1	-	27760321	HT29	viability after 10 days	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.4886896368124506	[323,252]	[351,291,129]	-6	hSpCas9	negative selection	5364848
155206243	155206265	1	+	27760321	HT29	viability after 10 days	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	-1.118678468907253	[222,173]	[110,107,122]	-8	hSpCas9	negative selection	5364849
155201195	155201217	1	-	27760321	MOLM13	viability	GTGTTGCCCTAGTGTAACGTGG	THBS3	ENSG00000169231	0.2943013718262003	[523,462]	[322,355]	2	hSpCas9	negative selection	5448308
155202003	155202025	1	-	27760321	MOLM13	viability	ACATCGATGAATGCAACGATGG	THBS3	ENSG00000169231	-0.4151689388957205	[406,344]	[110,198]	-3	hSpCas9	negative selection	5448309
155203102	155203124	1	+	27760321	MOLM13	viability	CATAATGGTGTTTCGGATCAGG	THBS3	ENSG00000169231	-1.3191452086266293	[257,180]	[47,49]	-6	hSpCas9	negative selection	5448310
155203222	155203244	1	-	27760321	MOLM13	viability	CGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.8994115775053988	[397,323]	[290,451]	6	hSpCas9	negative selection	5448311
155206243	155206265	1	+	27760321	MOLM13	viability	GTTGTCTTGGCGAGAATAGAGG	THBS3	ENSG00000169231	1.308097248455216	[244,222]	[538,145]	8	hSpCas9	negative selection	5448312
155207495	155207518	1	-	27661255	K562	viability	GAGCATCTGTAGGCACCCTAGGG	THBS3	ENSG00000169231	-0.016339512421187113	[582,721]	[548,482]	0	dCas9-KRAB	negative selection	5517135
155207864	155207887	1	-	27661255	K562	viability	GCTGAGAGGCATGGAGACGCAGG	THBS3	ENSG00000169231	-0.009920766769517503	[1045,757]	[777,669]	0	dCas9-KRAB	negative selection	5517136
155207886	155207909	1	-	27661255	K562	viability	GCCTGCCAGGGGTAGTGAGCCGG	THBS3	ENSG00000169231	0.12078060071536467	[356,480]	[341,378]	4	dCas9-KRAB	negative selection	5517137
155203222	155203245	1	-	27260156	BXPC3	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.09139399584570315	[464]	[456,528,465,635]	2	hSpCas9	negative selection	5575409
155202879	155202902	1	-	27260156	BXPC3	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.19534842860704033	[668]	[574,537,466,900]	-4	hSpCas9	negative selection	5575410
155203087	155203110	1	+	27260156	BXPC3	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.19033888734542115	[492]	[548,556,619,634]	4	hSpCas9	negative selection	5575411
155203101	155203124	1	-	27260156	BXPC3	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.1114187692570604	[464]	[505,505,473,625]	2	hSpCas9	negative selection	5639663
155203234	155203257	1	+	27260156	BXPC3	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.3127253375996468	[1864]	[1355,1470,1619,1891]	-6	hSpCas9	negative selection	5639664
155202912	155202935	1	-	27260156	BXPC3	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.3082419396539049	[563]	[518,862,731,828]	6	hSpCas9	negative selection	5639665
155203222	155203245	1	-	27260156	A673	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.04735820680425021	[464]	[509,504,601,539]	-1	hSpCas9	negative selection	5696660
155202879	155202902	1	-	27260156	A673	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.1640082612837327	[668]	[781,694,663,734]	-4	hSpCas9	negative selection	5696661
155203087	155203110	1	+	27260156	A673	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.15671154805603765	[492]	[730,644,541,733]	4	hSpCas9	negative selection	5696662
155203101	155203124	1	-	27260156	A673	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.10501763073073374	[464]	[687,480,408,518]	-3	hSpCas9	negative selection	5760914
155203234	155203257	1	+	27260156	A673	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.20545784236353803	[1864]	[2064,1808,1936,1972]	-5	hSpCas9	negative selection	5760915
155202912	155202935	1	-	27260156	A673	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.10019102135063179	[563]	[913,736,682,581]	2	hSpCas9	negative selection	5760916
155203222	155203245	1	-	27260156	A375	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.13765730478847082	[464]	[742,629,660,384]	2	hSpCas9	negative selection	5817911
155202879	155202902	1	-	27260156	A375	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.6767780018218122	[668]	[576,498,534,359]	-7	hSpCas9	negative selection	5817912
155203087	155203110	1	+	27260156	A375	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.2978013479269371	[492]	[536,481,402,453]	-4	hSpCas9	negative selection	5817913
155203101	155203124	1	-	27260156	A375	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.05066139569391816	[464]	[551,450,516,560]	0	hSpCas9	negative selection	5882165
155203234	155203257	1	+	27260156	A375	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.3724018954111279	[1864]	[1353,1752,1759,1844]	-5	hSpCas9	negative selection	5882166
155202912	155202935	1	-	27260156	A375	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.2766275339704254	[563]	[708,437,490,523]	-4	hSpCas9	negative selection	5882167
155203222	155203245	1	-	27260156	COLO741	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.14711996000565758	[464]	[651,471,496]	-3	hSpCas9	negative selection	5939162
155202879	155202902	1	-	27260156	COLO741	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.11808334883607513	[668]	[925,832,625]	-3	hSpCas9	negative selection	5939163
155203087	155203110	1	+	27260156	COLO741	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.1486109508704615	[492]	[803,697,606]	3	hSpCas9	negative selection	5939164
155203101	155203124	1	-	27260156	COLO741	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.2105920837379269	[464]	[649,505,402]	-4	hSpCas9	negative selection	6003416
155203234	155203257	1	+	27260156	COLO741	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.06172864208943696	[1864]	[2493,2158,2213]	-1	hSpCas9	negative selection	6003417
155202912	155202935	1	-	27260156	COLO741	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.02760138105551635	[563]	[768,814,628]	0	hSpCas9	negative selection	6003418
155203222	155203245	1	-	27260156	CAL120	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.37251628436103246	[464]	[411,451,470]	-5	hSpCas9	negative selection	6060413
155202879	155202902	1	-	27260156	CAL120	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.25329095821774833	[668]	[873,578,668]	-4	hSpCas9	negative selection	6060414
155203087	155203110	1	+	27260156	CAL120	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.09160273738722122	[492]	[430,630,641]	-1	hSpCas9	negative selection	6060415
155203101	155203124	1	-	27260156	CAL120	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.051369972903689554	[464]	[546,497,626]	0	hSpCas9	negative selection	6124667
155203234	155203257	1	+	27260156	CAL120	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.4703103253373295	[1864]	[2134,1396,1563]	-6	hSpCas9	negative selection	6124668
155202912	155202935	1	-	27260156	CAL120	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.1447132912131969	[563]	[674,637,597]	-2	hSpCas9	negative selection	6124669
155203222	155203245	1	-	27260156	CADOES1	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.12941733162337984	[464]	[534,537,403,412]	2	hSpCas9	negative selection	6181664
155202879	155202902	1	-	27260156	CADOES1	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.45350962016130214	[668]	[380,402,516,518]	-7	hSpCas9	negative selection	6181665
155203087	155203110	1	+	27260156	CADOES1	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.042351853012378086	[492]	[705,311,344,415]	0	hSpCas9	negative selection	6181666
155203101	155203124	1	-	27260156	CADOES1	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.0552694220310055	[464]	[320,493,364,487]	-1	hSpCas9	negative selection	6245918
155203234	155203257	1	+	27260156	CADOES1	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.2645527378845287	[1864]	[1552,1583,1241,1394]	-4	hSpCas9	negative selection	6245919
155202912	155202935	1	-	27260156	CADOES1	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.20504385928366847	[563]	[738,583,599,490]	3	hSpCas9	negative selection	6245920
155203222	155203245	1	-	27260156	EWS502	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.08725682556254752	[464]	[528,356,508,453]	-1	hSpCas9	negative selection	6302915
155202879	155202902	1	-	27260156	EWS502	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.443104547084977	[668]	[436,581,613,453]	-6	hSpCas9	negative selection	6302916
155203087	155203110	1	+	27260156	EWS502	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.2316395423794444	[492]	[421,710,866,461]	4	hSpCas9	negative selection	6302917
155203101	155203124	1	-	27260156	EWS502	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.3395031586195003	[464]	[712,562,458,753]	6	hSpCas9	negative selection	6367169
155203234	155203257	1	+	27260156	EWS502	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.09706760927615687	[1864]	[1725,2160,1728,1757]	-2	hSpCas9	negative selection	6367170
155202912	155202935	1	-	27260156	EWS502	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.27785945885887076	[563]	[519,698,1053,645]	5	hSpCas9	negative selection	6367171
155203222	155203245	1	-	27260156	EW8	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.194420260964853	[464]	[575,350,432,378]	3	hSpCas9	negative selection	6424166
155202879	155202902	1	-	27260156	EW8	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.3418388423716511	[668]	[549,448,426,297]	-6	hSpCas9	negative selection	6424167
155203087	155203110	1	+	27260156	EW8	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.03532845408134764	[492]	[504,348,353,368]	0	hSpCas9	negative selection	6424168
155203101	155203124	1	-	27260156	EW8	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.06044392178379775	[464]	[416,385,258,405]	-1	hSpCas9	negative selection	6488420
155203234	155203257	1	+	27260156	EW8	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.18670261591526427	[1864]	[1852,1106,1042,1409]	-4	hSpCas9	negative selection	6488421
155202912	155202935	1	-	27260156	EW8	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.12290688812887457	[563]	[598,413,546,431]	2	hSpCas9	negative selection	6488422
155203222	155203245	1	-	27260156	CORL105	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.10836039639912681	[464]	[579,642,661,472]	2	hSpCas9	negative selection	6545417
155202879	155202902	1	-	27260156	CORL105	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.28530238115726525	[668]	[688,621,501,736]	-5	hSpCas9	negative selection	6545418
155203087	155203110	1	+	27260156	CORL105	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.009499711196203735	[492]	[540,583,736,455]	0	hSpCas9	negative selection	6545419
155203101	155203124	1	-	27260156	CORL105	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.19981080298756282	[464]	[379,485,505,524]	-4	hSpCas9	negative selection	6609671
155203234	155203257	1	+	27260156	CORL105	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.3392568722871674	[1864]	[1862,1483,1896,1694]	-6	hSpCas9	negative selection	6609672
155202912	155202935	1	-	27260156	CORL105	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.17789286237283464	[563]	[660,444,779,484]	-3	hSpCas9	negative selection	6609673
155203222	155203245	1	-	27260156	HS294T	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.23721096936163696	[464]	[88,250,101,173]	-3	hSpCas9	negative selection	6666668
155202879	155202902	1	-	27260156	HS294T	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.5816068584878729	[668]	[140,117,182,269]	-7	hSpCas9	negative selection	6666669
155203087	155203110	1	+	27260156	HS294T	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.15394285524256646	[492]	[107,209,311,230]	2	hSpCas9	negative selection	6666670
155203101	155203124	1	-	27260156	HS294T	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.057001374031253695	[464]	[185,204,188,162]	0	hSpCas9	negative selection	6730922
155203234	155203257	1	+	27260156	HS294T	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.661216353328749	[1864]	[270,391,416,823]	-7	hSpCas9	negative selection	6730923
155202912	155202935	1	-	27260156	HS294T	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.6711878842067507	[563]	[105,122,148,179]	-7	hSpCas9	negative selection	6730924
155203222	155203245	1	-	27260156	HCC44	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.19094539169912622	[464]	[692,394,529,269]	-3	hSpCas9	negative selection	6787919
155202879	155202902	1	-	27260156	HCC44	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.5865179986410263	[668]	[410,297,578,748]	-7	hSpCas9	negative selection	6787920
155203087	155203110	1	+	27260156	HCC44	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.4983723599559432	[492]	[381,263,444,506]	-6	hSpCas9	negative selection	6787921
155203101	155203124	1	-	27260156	HCC44	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.3108096178008699	[464]	[659,675,809,487]	5	hSpCas9	negative selection	6852173
155203234	155203257	1	+	27260156	HCC44	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.46151704842907826	[1864]	[1770,1328,1840,1285]	-6	hSpCas9	negative selection	6852174
155202912	155202935	1	-	27260156	HCC44	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.23860682819246992	[563]	[558,590,554,452]	-4	hSpCas9	negative selection	6852175
155203222	155203245	1	-	27260156	G402	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.19273551766393265	[464]	[495,523,910,631]	2	hSpCas9	negative selection	6909170
155202879	155202902	1	-	27260156	G402	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.23779592881909117	[668]	[882,511,601,781]	-3	hSpCas9	negative selection	6909171
155203087	155203110	1	+	27260156	G402	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.06275231159924664	[492]	[1123,570,396,301]	-1	hSpCas9	negative selection	6909172
155203101	155203124	1	-	27260156	G402	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.5333951855156596	[464]	[459,1481,803,535]	6	hSpCas9	negative selection	6973424
155203234	155203257	1	+	27260156	G402	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.036687855827987725	[1864]	[2157,2159,2862,2121]	0	hSpCas9	negative selection	6973425
155202912	155202935	1	-	27260156	G402	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.00832196621447534	[563]	[1384,532,442,475]	0	hSpCas9	negative selection	6973426
155203222	155203245	1	-	27260156	L33	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.015446673687442274	[464]	[456,186,291,501]	0	hSpCas9	negative selection	7030421
155202879	155202902	1	-	27260156	L33	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.11041929946348683	[668]	[521,236,505,576]	-2	hSpCas9	negative selection	7030422
155203087	155203110	1	+	27260156	L33	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.372772960255155	[492]	[483,272,512,591]	7	hSpCas9	negative selection	7030423
155203101	155203124	1	-	27260156	L33	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.1382642318806135	[464]	[468,239,304,507]	3	hSpCas9	negative selection	7094675
155203234	155203257	1	+	27260156	L33	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.1413933285472062	[1864]	[1506,720,1141,1684]	-3	hSpCas9	negative selection	7094676
155202912	155202935	1	-	27260156	L33	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.14299272894103976	[563]	[686,275,358,557]	3	hSpCas9	negative selection	7094677
155203222	155203245	1	-	27260156	K562	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.07308000152122167	[464]	[603,438,234,317]	-1	hSpCas9	negative selection	7151672
155202879	155202902	1	-	27260156	K562	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.5470040871975178	[668]	[478,393,651,135]	-6	hSpCas9	negative selection	7151673
155203087	155203110	1	+	27260156	K562	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.036827314796303814	[492]	[605,422,535,261]	0	hSpCas9	negative selection	7151674
155203101	155203124	1	-	27260156	K562	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.8104830701819347	[464]	[591,1546,351,463]	8	hSpCas9	negative selection	7215926
155203234	155203257	1	+	27260156	K562	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.34592327885530083	[1864]	[1809,1240,1344,893]	-4	hSpCas9	negative selection	7215927
155202912	155202935	1	-	27260156	K562	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.629567682693472	[563]	[259,395,327,308]	-6	hSpCas9	negative selection	7215928
155203222	155203245	1	-	27260156	HT29	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.004609891605854385	[464]	[548,710,518,503]	0	hSpCas9	negative selection	7272923
155202879	155202902	1	-	27260156	HT29	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.4289533030294686	[668]	[776,535,561,550]	-7	hSpCas9	negative selection	7272924
155203087	155203110	1	+	27260156	HT29	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.15740108300887817	[492]	[739,560,341,521]	-3	hSpCas9	negative selection	7272925
155203101	155203124	1	-	27260156	HT29	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.01464118135984277	[464]	[588,668,519,477]	0	hSpCas9	negative selection	7337177
155203234	155203257	1	+	27260156	HT29	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.2179446627429804	[1864]	[1888,2407,1925,1633]	-4	hSpCas9	negative selection	7337178
155202912	155202935	1	-	27260156	HT29	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.2900979130298139	[563]	[824,995,963,603]	5	hSpCas9	negative selection	7337179
155203222	155203245	1	-	27260156	MHHES1	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.0973023852566691	[464]	[496,562,727,457]	1	hSpCas9	negative selection	7394174
155202879	155202902	1	-	27260156	MHHES1	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.3341401457065152	[668]	[602,807,669,371]	-6	hSpCas9	negative selection	7394175
155203087	155203110	1	+	27260156	MHHES1	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.07639861818530662	[492]	[643,597,604,507]	1	hSpCas9	negative selection	7394176
155203101	155203124	1	-	27260156	MHHES1	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.17431075763342171	[464]	[612,678,523,553]	3	hSpCas9	negative selection	7458428
155203234	155203257	1	+	27260156	MHHES1	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.2476715196242827	[1864]	[1870,2153,1762,1388]	-5	hSpCas9	negative selection	7458429
155202912	155202935	1	-	27260156	MHHES1	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.14969544947339525	[563]	[980,586,733,556]	2	hSpCas9	negative selection	7458430
155203222	155203245	1	-	27260156	MEWO	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.09666700854094634	[464]	[506,373,358]	-2	hSpCas9	negative selection	7515425
155202879	155202902	1	-	27260156	MEWO	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.18190231169041288	[668]	[764,435,495]	-4	hSpCas9	negative selection	7515426
155203087	155203110	1	+	27260156	MEWO	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.08756128195539069	[492]	[545,489,444]	2	hSpCas9	negative selection	7515427
155203101	155203124	1	-	27260156	MEWO	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.15643916831020407	[464]	[542,431,490]	3	hSpCas9	negative selection	7579679
155203234	155203257	1	+	27260156	MEWO	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.1320783347763601	[1864]	[1747,1667,1389]	-3	hSpCas9	negative selection	7579680
155202912	155202935	1	-	27260156	MEWO	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.3302084840277605	[563]	[812,651,553]	7	hSpCas9	negative selection	7579681
155203222	155203245	1	-	27260156	LNCAPCLONEFGC	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.24743850417082755	[464]	[363,243,460,372]	-4	hSpCas9	negative selection	7636676
155202879	155202902	1	-	27260156	LNCAPCLONEFGC	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.7190036645847363	[668]	[369,292,412,407]	-8	hSpCas9	negative selection	7636677
155203087	155203110	1	+	27260156	LNCAPCLONEFGC	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.172733075069383	[492]	[498,315,383,386]	-3	hSpCas9	negative selection	7636678
155203101	155203124	1	-	27260156	LNCAPCLONEFGC	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.49087933586144006	[464]	[124,374,520,208]	-6	hSpCas9	negative selection	7700930
155203234	155203257	1	+	27260156	LNCAPCLONEFGC	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.3520159120734836	[1864]	[1350,1130,1492,1355]	-5	hSpCas9	negative selection	7700931
155202912	155202935	1	-	27260156	LNCAPCLONEFGC	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.6470587120148033	[563]	[217,195,524,405]	-7	hSpCas9	negative selection	7700932
155203222	155203245	1	-	27260156	PANC0327	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.1546667337246044	[464]	[244,597,624,335]	2	hSpCas9	negative selection	7757927
155202879	155202902	1	-	27260156	PANC0327	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.9692039253802631	[668]	[329,203,273,420]	-8	hSpCas9	negative selection	7757928
155203087	155203110	1	+	27260156	PANC0327	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.17520115657550622	[492]	[858,279,315,579]	2	hSpCas9	negative selection	7757929
155203101	155203124	1	-	27260156	PANC0327	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.18888848238016478	[464]	[302,276,601,273]	-3	hSpCas9	negative selection	7822181
155203234	155203257	1	+	27260156	PANC0327	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.4676068679653045	[1864]	[1084,1210,1248,1235]	-6	hSpCas9	negative selection	7822182
155202912	155202935	1	-	27260156	PANC0327	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-1.0208120057617585	[563]	[192,209,301,282]	-8	hSpCas9	negative selection	7822183
155203222	155203245	1	-	27260156	NCIH2009	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.36424124188588425	[464]	[523,510,481]	-5	hSpCas9	negative selection	7879178
155202879	155202902	1	-	27260156	NCIH2009	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.11273875923482096	[668]	[776,674,1125]	-1	hSpCas9	negative selection	7879179
155203087	155203110	1	+	27260156	NCIH2009	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.07671580963913475	[492]	[875,560,566]	-1	hSpCas9	negative selection	7879180
155203101	155203124	1	-	27260156	NCIH2009	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.2565138477650346	[464]	[526,394,707]	-4	hSpCas9	negative selection	7943432
155203234	155203257	1	+	27260156	NCIH2009	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.22109555628999766	[1864]	[2893,2056,1884]	-3	hSpCas9	negative selection	7943433
155202912	155202935	1	-	27260156	NCIH2009	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.16054738261089374	[563]	[1070,438,680]	-2	hSpCas9	negative selection	7943434
155203222	155203245	1	-	27260156	NCIH1373	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.13101319716327361	[464]	[348,510,368,173]	-1	hSpCas9	negative selection	8000429
155202879	155202902	1	-	27260156	NCIH1373	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	0.009316481663362408	[668]	[824,1142,586,107]	0	hSpCas9	negative selection	8000430
155203087	155203110	1	+	27260156	NCIH1373	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.3121732372595866	[492]	[562,359,461,109]	-3	hSpCas9	negative selection	8000431
155203101	155203124	1	-	27260156	NCIH1373	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.15816387551221428	[464]	[774,302,446,105]	-1	hSpCas9	negative selection	8064683
155203234	155203257	1	+	27260156	NCIH1373	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.5262525447411857	[1864]	[1340,1468,1534,375]	-5	hSpCas9	negative selection	8064684
155202912	155202935	1	-	27260156	NCIH1373	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.8232018946262872	[563]	[478,214,478,73]	-7	hSpCas9	negative selection	8064685
155203222	155203245	1	-	27260156	PATU8902	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.263716841420288	[464]	[765,764,355,1400]	2	hSpCas9	negative selection	8121680
155202879	155202902	1	-	27260156	PATU8902	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.32011549670159956	[668]	[938,933,380,827]	-3	hSpCas9	negative selection	8121681
155203087	155203110	1	+	27260156	PATU8902	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-1.3460954113354417	[492]	[430,267,213,164]	-8	hSpCas9	negative selection	8121682
155203101	155203124	1	-	27260156	PATU8902	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-1.2488100456538238	[464]	[342,335,217,194]	-8	hSpCas9	negative selection	8185934
155203234	155203257	1	+	27260156	PATU8902	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.47276216892851464	[1864]	[2173,1976,1193,2356]	-4	hSpCas9	negative selection	8185935
155202912	155202935	1	-	27260156	PATU8902	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.590934583116105	[563]	[313,324,742,660]	-5	hSpCas9	negative selection	8185936
155203222	155203245	1	-	27260156	PANC1	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.09215376704461078	[464]	[401,564,277,297]	-1	hSpCas9	negative selection	8242931
155202879	155202902	1	-	27260156	PANC1	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.23478646610246567	[668]	[370,580,493,515]	-4	hSpCas9	negative selection	8242932
155203087	155203110	1	+	27260156	PANC1	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.5068199344285184	[492]	[560,633,718,506]	7	hSpCas9	negative selection	8242933
155203101	155203124	1	-	27260156	PANC1	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.02734391751864146	[464]	[314,530,531,239]	0	hSpCas9	negative selection	8307185
155203234	155203257	1	+	27260156	PANC1	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.18112925098403143	[1864]	[1416,1612,1223,1412]	-3	hSpCas9	negative selection	8307186
155202912	155202935	1	-	27260156	PANC1	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.3881553024347393	[563]	[396,805,857,524]	6	hSpCas9	negative selection	8307187
155203222	155203245	1	-	27260156	PANC0813	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.002534065538687985	[464]	[774,381,563,483]	0	hSpCas9	negative selection	8364182
155202879	155202902	1	-	27260156	PANC0813	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.013222522890034227	[668]	[966,919,820,441]	0	hSpCas9	negative selection	8364183
155203087	155203110	1	+	27260156	PANC0813	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.08208296636117056	[492]	[670,586,546,648]	1	hSpCas9	negative selection	8364184
155203101	155203124	1	-	27260156	PANC0813	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.03315517017217167	[464]	[370,576,470,690]	0	hSpCas9	negative selection	8428436
155203234	155203257	1	+	27260156	PANC0813	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.1763682050948827	[1864]	[2241,1916,2159,1486]	-3	hSpCas9	negative selection	8428437
155202912	155202935	1	-	27260156	PANC0813	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.31902863461734693	[563]	[776,540,570,271]	-5	hSpCas9	negative selection	8428438
155203222	155203245	1	-	27260156	RDES	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.1047745817351438	[464]	[506,516,446,493]	-2	hSpCas9	negative selection	8485433
155202879	155202902	1	-	27260156	RDES	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.6065690460318953	[668]	[545,360,520,594]	-8	hSpCas9	negative selection	8485434
155203087	155203110	1	+	27260156	RDES	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.403574055794147	[492]	[471,321,420,494]	-6	hSpCas9	negative selection	8485435
155203101	155203124	1	-	27260156	RDES	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.24662504109531094	[464]	[463,450,708,1011]	4	hSpCas9	negative selection	8549687
155203234	155203257	1	+	27260156	RDES	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.36554835990052226	[1864]	[1432,1469,1718,2126]	-6	hSpCas9	negative selection	8549688
155202912	155202935	1	-	27260156	RDES	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.3079941187970342	[563]	[480,418,660,545]	-5	hSpCas9	negative selection	8549689
155203222	155203245	1	-	27260156	PC3	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.0608227100931594	[464]	[235,289,973,552]	-1	hSpCas9	negative selection	8606684
155202879	155202902	1	-	27260156	PC3	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.35066745259982635	[668]	[311,498,1014,501]	-7	hSpCas9	negative selection	8606685
155203087	155203110	1	+	27260156	PC3	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.06452356065383177	[492]	[200,461,823,622]	-1	hSpCas9	negative selection	8606686
155203101	155203124	1	-	27260156	PC3	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.221185304662896	[464]	[285,389,644,369]	-5	hSpCas9	negative selection	8670938
155203234	155203257	1	+	27260156	PC3	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.29195082476619527	[1864]	[862,1249,2668,1926]	-6	hSpCas9	negative selection	8670939
155202912	155202935	1	-	27260156	PC3	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.02833462965658401	[563]	[436,565,957,470]	0	hSpCas9	negative selection	8670940
155203222	155203245	1	-	27260156	PATU8988T	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.06694886733086258	[464]	[461,490,476,452]	1	hSpCas9	negative selection	8727935
155202879	155202902	1	-	27260156	PATU8988T	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.49031763533559614	[668]	[510,514,528,274]	-7	hSpCas9	negative selection	8727936
155203087	155203110	1	+	27260156	PATU8988T	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.1309877683546939	[492]	[533,388,295,525]	-2	hSpCas9	negative selection	8727937
155203101	155203124	1	-	27260156	PATU8988T	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.08348000834149	[464]	[433,608,345,316]	-1	hSpCas9	negative selection	8792189
155203234	155203257	1	+	27260156	PATU8988T	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.07581326035896718	[1864]	[1536,1690,1543,2098]	-1	hSpCas9	negative selection	8792190
155202912	155202935	1	-	27260156	PATU8988T	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.3297742687297798	[563]	[703,553,822,640]	5	hSpCas9	negative selection	8792191
155203222	155203245	1	-	27260156	T47D	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.20324187041147437	[464]	[565,380,495,445]	-4	hSpCas9	negative selection	8849186
155202879	155202902	1	-	27260156	T47D	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.5869325688313217	[668]	[538,515,540,477]	-8	hSpCas9	negative selection	8849187
155203087	155203110	1	+	27260156	T47D	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.3576861833869072	[492]	[468,314,397,628]	-6	hSpCas9	negative selection	8849188
155203101	155203124	1	-	27260156	T47D	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.056264872410727654	[464]	[530,549,519,478]	-1	hSpCas9	negative selection	8913440
155203234	155203257	1	+	27260156	T47D	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.39688985860336135	[1864]	[1837,1667,1516,1575]	-7	hSpCas9	negative selection	8913441
155202912	155202935	1	-	27260156	T47D	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.2210011442867918	[563]	[666,472,541,581]	-5	hSpCas9	negative selection	8913442
155203222	155203245	1	-	27260156	SU8686	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.19322284935330258	[464]	[444,309,409,461]	-3	hSpCas9	negative selection	8970437
155202879	155202902	1	-	27260156	SU8686	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	0.06483948805929174	[668]	[599,601,854,748]	1	hSpCas9	negative selection	8970438
155203087	155203110	1	+	27260156	SU8686	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.016998138283683947	[492]	[501,456,447,584]	0	hSpCas9	negative selection	8970439
155203101	155203124	1	-	27260156	SU8686	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.19757216126800303	[464]	[532,542,537,487]	3	hSpCas9	negative selection	9034691
155203234	155203257	1	+	27260156	SU8686	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.23142139694213193	[1864]	[1384,1297,1870,1843]	-4	hSpCas9	negative selection	9034692
155202912	155202935	1	-	27260156	SU8686	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.1838081746220021	[563]	[333,502,574,587]	-3	hSpCas9	negative selection	9034693
155203222	155203245	1	-	27260156	SKES1	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.08604703275214522	[464]	[474,535,542,420]	2	hSpCas9	negative selection	9091688
155202879	155202902	1	-	27260156	SKES1	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.45975269017912623	[668]	[528,515,348,545]	-7	hSpCas9	negative selection	9091689
155203087	155203110	1	+	27260156	SKES1	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.01856716779452762	[492]	[596,579,555,300]	0	hSpCas9	negative selection	9091690
155203101	155203124	1	-	27260156	SKES1	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.3456662556863702	[464]	[661,657,612,452]	7	hSpCas9	negative selection	9155942
155203234	155203257	1	+	27260156	SKES1	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.20331511122424195	[1864]	[1771,1741,1704,1300]	-4	hSpCas9	negative selection	9155943
155202912	155202935	1	-	27260156	SKES1	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.04594640930844934	[563]	[638,635,641,431]	1	hSpCas9	negative selection	9155944
155203222	155203245	1	-	27260156	TOV112D	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.13663903318135173	[464]	[366,595,378,707]	2	hSpCas9	negative selection	9212939
155202879	155202902	1	-	27260156	TOV112D	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.6211281011546924	[668]	[462,529,398,376]	-8	hSpCas9	negative selection	9212940
155203087	155203110	1	+	27260156	TOV112D	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	0.12768492271012544	[492]	[418,905,553,362]	2	hSpCas9	negative selection	9212941
155203101	155203124	1	-	27260156	TOV112D	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.47648100719018693	[464]	[306,500,308,261]	-7	hSpCas9	negative selection	9277193
155203234	155203257	1	+	27260156	TOV112D	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.21432019018148374	[1864]	[1505,2214,1442,1418]	-4	hSpCas9	negative selection	9277194
155202912	155202935	1	-	27260156	TOV112D	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	0.29043549964507365	[563]	[840,1028,510,482]	5	hSpCas9	negative selection	9277195
155203222	155203245	1	-	27260156	TC71	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	0.0606619327088107	[464]	[509,512,516,540]	1	hSpCas9	negative selection	9334190
155202879	155202902	1	-	27260156	TC71	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.21195738707943612	[668]	[589,643,623,618]	-5	hSpCas9	negative selection	9334191
155203087	155203110	1	+	27260156	TC71	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.028658170272050115	[492]	[453,534,625,450]	0	hSpCas9	negative selection	9334192
155203101	155203124	1	-	27260156	TC71	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	0.0878761314834438	[464]	[437,656,547,473]	2	hSpCas9	negative selection	9398444
155203234	155203257	1	+	27260156	TC71	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.24789869772426254	[1864]	[1358,1801,1715,1874]	-6	hSpCas9	negative selection	9398445
155202912	155202935	1	-	27260156	TC71	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.050237216695338704	[563]	[522,597,563,656]	-1	hSpCas9	negative selection	9398446
155203222	155203245	1	-	27260156	TC32	viability	GCGGGATGATATACGAGACCAGG	THBS3	ENSG00000169231	-0.5573860788206593	[464]	[252,189,416,382]	-8	hSpCas9	negative selection	9455441
155202879	155202902	1	-	27260156	TC32	viability	ATGGAAGTGTACGAGTACCCAGG	THBS3	ENSG00000169231	-0.792273775386725	[668]	[533,198,382,356]	-9	hSpCas9	negative selection	9455442
155203087	155203110	1	+	27260156	TC32	viability	GCACACCTGACACTCCATAATGG	THBS3	ENSG00000169231	-0.5269662875023403	[492]	[334,198,519,290]	-7	hSpCas9	negative selection	9455443
155203101	155203124	1	-	27260156	TC32	viability	CCTGATCCGAAACACCATTATGG	THBS3	ENSG00000169231	-0.3769243860100565	[464]	[243,327,355,419]	-6	hSpCas9	negative selection	9519695
155203234	155203257	1	+	27260156	TC32	viability	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.46029210312915714	[1864]	[1096,1175,1565,1286]	-7	hSpCas9	negative selection	9519696
155202912	155202935	1	-	27260156	TC32	viability	AGCCCCAATCCCTGCTTCCGAGG	THBS3	ENSG00000169231	-0.2614112567408361	[563]	[350,319,682,491]	-5	hSpCas9	negative selection	9519697
155202302	155202325	1	-	27869803	HPAFII	viability after 27 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.6504956607602127	[455]	[101,194,NaN]	-5	hSpCas9	negative selection	9529319
155202902	155202925	1	+	27869803	HPAFII	viability after 27 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	1.3243757941260357	[822]	[1484,748,NaN]	9	hSpCas9	negative selection	9529320
155203234	155203257	1	+	27869803	HPAFII	viability after 27 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.1568117329146691	[159]	[111,44,NaN]	-1	hSpCas9	negative selection	9529321
155203499	155203522	1	+	27869803	HPAFII	viability after 27 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.9273170686988625	[497]	[516,481,NaN]	7	hSpCas9	negative selection	9529322
155205256	155205279	1	-	27869803	HPAFII	viability after 27 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.2595878616108478	[624]	[460,336,NaN]	2	hSpCas9	negative selection	9529323
155207852	155207875	1	-	27869803	HPAFII	viability after 27 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-1.7619709476226524	[77]	[16,7,NaN]	-8	hSpCas9	negative selection	9529324
155202302	155202325	1	-	27869803	HPAFII	viability after 15 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.35832824415652564	[455]	[311,425,NaN]	-4	hSpCas9	negative selection	9611768
155202902	155202925	1	+	27869803	HPAFII	viability after 15 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.5160234527690937	[822]	[1574,1071,NaN]	6	hSpCas9	negative selection	9611769
155203234	155203257	1	+	27869803	HPAFII	viability after 15 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.570296480303796	[159]	[211,55,NaN]	-6	hSpCas9	negative selection	9611770
155203499	155203522	1	+	27869803	HPAFII	viability after 15 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.7275318591316169	[497]	[1011,807,NaN]	7	hSpCas9	negative selection	9611771
155205256	155205279	1	-	27869803	HPAFII	viability after 15 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	-0.12290704407750352	[624]	[807,497,NaN]	-1	hSpCas9	negative selection	9611772
155207852	155207875	1	-	27869803	HPAFII	viability after 15 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-0.5573811275978493	[77]	[35,69,NaN]	-6	hSpCas9	negative selection	9611773
155202302	155202325	1	-	27869803	ASPC1	viability after 36 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	1.6769049818842565	[929]	[1621,1006,641]	9	hSpCas9	negative selection	9694217
155202902	155202925	1	+	27869803	ASPC1	viability after 36 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.7777149528924527	[1780]	[646,1330,1137]	7	hSpCas9	negative selection	9694218
155203234	155203257	1	+	27869803	ASPC1	viability after 36 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.4318231494723649	[243]	[82,85,158]	4	hSpCas9	negative selection	9694219
155203499	155203522	1	+	27869803	ASPC1	viability after 36 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.5272318613735438	[1084]	[730,666,313]	5	hSpCas9	negative selection	9694220
155205256	155205279	1	-	27869803	ASPC1	viability after 36 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.6645354810260743	[1249]	[1159,223,726]	6	hSpCas9	negative selection	9694221
155207852	155207875	1	-	27869803	ASPC1	viability after 36 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	0.6846051227759017	[247]	[186,103,131]	6	hSpCas9	negative selection	9694222
155202302	155202325	1	-	27869803	PATU8988S	viability after 35 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	0.8295981312283022	[857]	[887,338,NaN]	8	hSpCas9	negative selection	9776666
155202902	155202925	1	+	27869803	PATU8988S	viability after 35 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	-0.02980577894642744	[1426]	[550,574,NaN]	0	hSpCas9	negative selection	9776667
155203234	155203257	1	+	27869803	PATU8988S	viability after 35 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.18880302481734057	[310]	[61,157,NaN]	-2	hSpCas9	negative selection	9776668
155203499	155203522	1	+	27869803	PATU8988S	viability after 35 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.43201705859576167	[1115]	[556,655,NaN]	5	hSpCas9	negative selection	9776669
155205256	155205279	1	-	27869803	PATU8988S	viability after 35 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.1226389376383229	[996]	[510,362,NaN]	1	hSpCas9	negative selection	9776670
155207852	155207875	1	-	27869803	PATU8988S	viability after 35 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	0.6889259420629449	[177]	[145,84,NaN]	7	hSpCas9	negative selection	9776671
155202302	155202325	1	-	27869803	PATU8988S	viability after 31 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	0.8470915977448187	[857]	[775,410,NaN]	8	hSpCas9	negative selection	9859115
155202902	155202925	1	+	27869803	PATU8988S	viability after 31 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	0.08991572590252939	[1426]	[598,613,NaN]	1	hSpCas9	negative selection	9859116
155203234	155203257	1	+	27869803	PATU8988S	viability after 31 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	0.01422608272030601	[310]	[115,136,NaN]	0	hSpCas9	negative selection	9859117
155203499	155203522	1	+	27869803	PATU8988S	viability after 31 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	0.24059301464412042	[1115]	[501,555,NaN]	3	hSpCas9	negative selection	9859118
155205256	155205279	1	-	27869803	PATU8988S	viability after 31 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	-0.04674378837668158	[996]	[350,427,NaN]	0	hSpCas9	negative selection	9859119
155207852	155207875	1	-	27869803	PATU8988S	viability after 31 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	1.3329769385565027	[177]	[202,147,NaN]	9	hSpCas9	negative selection	9859120
155202302	155202325	1	-	27869803	HPAFII	viability after 35 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-0.7432277095583303	[455]	[72,210,NaN]	-4	hSpCas9	negative selection	9941564
155202902	155202925	1	+	27869803	HPAFII	viability after 35 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	1.6479123005996523	[822]	[1585,989,NaN]	9	hSpCas9	negative selection	9941565
155203234	155203257	1	+	27869803	HPAFII	viability after 35 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.548972742621652	[159]	[76,30,NaN]	-3	hSpCas9	negative selection	9941566
155203499	155203522	1	+	27869803	HPAFII	viability after 35 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	1.246031079758657	[497]	[549,651,NaN]	8	hSpCas9	negative selection	9941567
155205256	155205279	1	-	27869803	HPAFII	viability after 35 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	-0.3095271944328917	[624]	[283,222,NaN]	-2	hSpCas9	negative selection	9941568
155207852	155207875	1	-	27869803	HPAFII	viability after 35 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-2.293368904394069	[77]	[0,15,NaN]	-8	hSpCas9	negative selection	9941569
155202302	155202325	1	-	27869803	HPAFII	viability after 31 days	TCGAGGGTACAAGGGCACACAGG	THBS3	ENSG00000169231	-1.025759957910808	[455]	[62,193,NaN]	-6	hSpCas9	negative selection	10024013
155202902	155202925	1	+	27869803	HPAFII	viability after 31 days	GCAGTCCACACCTCGGAAGCAGG	THBS3	ENSG00000169231	1.4923714276498468	[822]	[1522,1055,NaN]	9	hSpCas9	negative selection	10024014
155203234	155203257	1	+	27869803	HPAFII	viability after 31 days	TATCATCCCGCAGCTCCACCAGG	THBS3	ENSG00000169231	-0.9591821200309856	[159]	[27,65,NaN]	-6	hSpCas9	negative selection	10024015
155203499	155203522	1	+	27869803	HPAFII	viability after 31 days	TGTGGCCTACTCACCTAGAATGG	THBS3	ENSG00000169231	1.0667010120249216	[497]	[538,635,NaN]	7	hSpCas9	negative selection	10024016
155205256	155205279	1	-	27869803	HPAFII	viability after 31 days	GCCGTGAACCTACAGCAAGCGGG	THBS3	ENSG00000169231	0.07776423161678347	[624]	[485,243,NaN]	0	hSpCas9	negative selection	10024017
155207852	155207875	1	-	27869803	HPAFII	viability after 31 days	GGAGACGCAGGAACTTCGGGGGG	THBS3	ENSG00000169231	-3.8264265339684886	[77]	[4,0,NaN]	-9	hSpCas9	negative selection	10024018
155207829	155207852	1	+	28162770	P31FUJ	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	0.25118264858195655	[142]	[199]	2	hSpCas9	negative selection	10250227
155196092	155196115	1	-	28162770	P31FUJ	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	0.5616675914365424	[240]	[417]	6	hSpCas9	negative selection	10250228
155201524	155201547	1	+	28162770	P31FUJ	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-0.6748067512934917	[71]	[52]	-5	hSpCas9	negative selection	10250229
155201146	155201169	1	-	28162770	P31FUJ	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-0.5718262931250484	[190]	[150]	-5	hSpCas9	negative selection	10250230
155200489	155200512	1	-	28162770	P31FUJ	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.22496827985299783	[157]	[216]	2	hSpCas9	negative selection	10250231
155200038	155200061	1	-	28162770	P31FUJ	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-0.445273911952134	[313]	[270]	-4	hSpCas9	negative selection	10250232
155198574	155198597	1	-	28162770	P31FUJ	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	0.25172039518574924	[227]	[318]	2	hSpCas9	negative selection	10250233
155198424	155198447	1	+	28162770	P31FUJ	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-0.26063641261110426	[156]	[153]	-2	hSpCas9	negative selection	10250234
155198134	155198157	1	-	28162770	P31FUJ	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.10878968245055654	[712]	[776]	-1	hSpCas9	negative selection	10250235
155197489	155197512	1	-	28162770	P31FUJ	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-0.25848884807802824	[339]	[333]	-2	hSpCas9	negative selection	10250236
155207829	155207852	1	+	28162770	TF1	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	NaN	[NaN]	[92]	1	hSpCas9	negative selection	10419593
155196092	155196115	1	-	28162770	TF1	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10419594
155201524	155201547	1	+	28162770	TF1	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10419595
155201146	155201169	1	-	28162770	TF1	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	NaN	[NaN]	[168]	1	hSpCas9	negative selection	10419596
155200489	155200512	1	-	28162770	TF1	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	NaN	[NaN]	[267]	1	hSpCas9	negative selection	10419597
155200038	155200061	1	-	28162770	TF1	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	NaN	[NaN]	[175]	1	hSpCas9	negative selection	10419598
155198574	155198597	1	-	28162770	TF1	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	NaN	[NaN]	[181]	1	hSpCas9	negative selection	10419599
155198424	155198447	1	+	28162770	TF1	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10419600
155198134	155198157	1	-	28162770	TF1	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	NaN	[NaN]	[388]	1	hSpCas9	negative selection	10419601
155197489	155197512	1	-	28162770	TF1	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10419602
155207829	155207852	1	+	28162770	SKM1	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-0.8585275740471197	[39]	[38]	-6	hSpCas9	negative selection	10588959
155196092	155196115	1	-	28162770	SKM1	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	0.40039072331444236	[50]	[118]	4	hSpCas9	negative selection	10588960
155201524	155201547	1	+	28162770	SKM1	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-0.8220016980220057	[17]	[17]	-6	hSpCas9	negative selection	10588961
155201146	155201169	1	-	28162770	SKM1	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-1.3420087569023917	[75]	[52]	-7	hSpCas9	negative selection	10588962
155200489	155200512	1	-	28162770	SKM1	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.6461471377164006	[59]	[165]	6	hSpCas9	negative selection	10588963
155200038	155200061	1	-	28162770	SKM1	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-0.9624829215718361	[96]	[87]	-6	hSpCas9	negative selection	10588964
155198574	155198597	1	-	28162770	SKM1	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	0.43433805523778	[53]	[128]	4	hSpCas9	negative selection	10588965
155198424	155198447	1	+	28162770	SKM1	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	0.01852008797079785	[42]	[76]	0	hSpCas9	negative selection	10588966
155198134	155198157	1	-	28162770	SKM1	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.2564045221677804	[149]	[221]	-2	hSpCas9	negative selection	10588967
155197489	155197512	1	-	28162770	SKM1	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-0.994468894026771	[70]	[62]	-6	hSpCas9	negative selection	10588968
155207829	155207852	1	+	28162770	SKM1	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-0.8585275740471197	[39]	[38]	-6	hSpCas9	negative selection	10758325
155196092	155196115	1	-	28162770	SKM1	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	0.40039072331444236	[50]	[118]	4	hSpCas9	negative selection	10758326
155201524	155201547	1	+	28162770	SKM1	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-0.8220016980220057	[17]	[17]	-6	hSpCas9	negative selection	10758327
155201146	155201169	1	-	28162770	SKM1	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-1.3420087569023917	[75]	[52]	-7	hSpCas9	negative selection	10758328
155200489	155200512	1	-	28162770	SKM1	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.6461471377164006	[59]	[165]	6	hSpCas9	negative selection	10758329
155200038	155200061	1	-	28162770	SKM1	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-0.9624829215718361	[96]	[87]	-6	hSpCas9	negative selection	10758330
155198574	155198597	1	-	28162770	SKM1	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	0.43433805523778	[53]	[128]	4	hSpCas9	negative selection	10758331
155198424	155198447	1	+	28162770	SKM1	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	0.01852008797079785	[42]	[76]	0	hSpCas9	negative selection	10758332
155198134	155198157	1	-	28162770	SKM1	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.2564045221677804	[149]	[221]	-2	hSpCas9	negative selection	10758333
155197489	155197512	1	-	28162770	SKM1	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-0.994468894026771	[70]	[62]	-6	hSpCas9	negative selection	10758334
155207829	155207852	1	+	28162770	PL21	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	1.6631115908318659	[147]	[203]	9	hSpCas9	negative selection	10927691
155196092	155196115	1	-	28162770	PL21	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	-0.17022883545579526	[211]	[81]	-1	hSpCas9	negative selection	10927692
155201524	155201547	1	+	28162770	PL21	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-0.19472000285189317	[70]	[26]	-1	hSpCas9	negative selection	10927693
155201146	155201169	1	-	28162770	PL21	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	0.4987979300538353	[199]	[122]	4	hSpCas9	negative selection	10927694
155200489	155200512	1	-	28162770	PL21	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.26206736363252214	[227]	[118]	2	hSpCas9	negative selection	10927695
155200038	155200061	1	-	28162770	PL21	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-0.5160674195100887	[252]	[76]	-4	hSpCas9	negative selection	10927696
155198574	155198597	1	-	28162770	PL21	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	-0.08576925759706026	[177]	[72]	0	hSpCas9	negative selection	10927697
155198424	155198447	1	+	28162770	PL21	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-0.9781976267691923	[171]	[37]	-6	hSpCas9	negative selection	10927698
155198134	155198157	1	-	28162770	PL21	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.5223264099817709	[461]	[139]	-4	hSpCas9	negative selection	10927699
155197489	155197512	1	-	28162770	PL21	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-0.6585836986586883	[242]	[66]	-4	hSpCas9	negative selection	10927700
155207829	155207852	1	+	28162770	P31FUJ	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	0.25118264858195655	[142]	[199]	2	hSpCas9	negative selection	11097057
155196092	155196115	1	-	28162770	P31FUJ	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	0.5616675914365424	[240]	[417]	6	hSpCas9	negative selection	11097058
155201524	155201547	1	+	28162770	P31FUJ	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-0.6748067512934917	[71]	[52]	-5	hSpCas9	negative selection	11097059
155201146	155201169	1	-	28162770	P31FUJ	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-0.5718262931250484	[190]	[150]	-5	hSpCas9	negative selection	11097060
155200489	155200512	1	-	28162770	P31FUJ	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.22496827985299783	[157]	[216]	2	hSpCas9	negative selection	11097061
155200038	155200061	1	-	28162770	P31FUJ	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-0.445273911952134	[313]	[270]	-4	hSpCas9	negative selection	11097062
155198574	155198597	1	-	28162770	P31FUJ	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	0.25172039518574924	[227]	[318]	2	hSpCas9	negative selection	11097063
155198424	155198447	1	+	28162770	P31FUJ	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-0.26063641261110426	[156]	[153]	-2	hSpCas9	negative selection	11097064
155198134	155198157	1	-	28162770	P31FUJ	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.10878968245055654	[712]	[776]	-1	hSpCas9	negative selection	11097065
155197489	155197512	1	-	28162770	P31FUJ	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-0.25848884807802824	[339]	[333]	-2	hSpCas9	negative selection	11097066
155207829	155207852	1	+	28162770	OCIAML5	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-1.6594214929216013	[90]	[51]	-7	hSpCas9	negative selection	11266423
155196092	155196115	1	-	28162770	OCIAML5	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	0.612143770396549	[136]	[377]	5	hSpCas9	negative selection	11266424
155201524	155201547	1	+	28162770	OCIAML5	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-0.18464190995086782	[33]	[53]	-1	hSpCas9	negative selection	11266425
155201146	155201169	1	-	28162770	OCIAML5	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-1.1195468817289829	[129]	[107]	-6	hSpCas9	negative selection	11266426
155200489	155200512	1	-	28162770	OCIAML5	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	-0.9034134508642174	[142]	[137]	-5	hSpCas9	negative selection	11266427
155200038	155200061	1	-	28162770	OCIAML5	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-0.7646037296136576	[127]	[135]	-5	hSpCas9	negative selection	11266428
155198574	155198597	1	-	28162770	OCIAML5	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	-0.4677258688080697	[94]	[123]	-3	hSpCas9	negative selection	11266429
155198424	155198447	1	+	28162770	OCIAML5	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-1.1470733664360708	[145]	[118]	-6	hSpCas9	negative selection	11266430
155198134	155198157	1	-	28162770	OCIAML5	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.6990107994876102	[410]	[456]	-4	hSpCas9	negative selection	11266431
155197489	155197512	1	-	28162770	OCIAML5	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-0.34005667091621977	[168]	[240]	-2	hSpCas9	negative selection	11266432
155207829	155207852	1	+	28162770	EOL1	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	0.6207670233934317	[315]	[255]	5	hSpCas9	negative selection	11435789
155196092	155196115	1	-	28162770	EOL1	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	0.46870405590380504	[250]	[182]	4	hSpCas9	negative selection	11435790
155201524	155201547	1	+	28162770	EOL1	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-0.7589785636342112	[105]	[32]	-5	hSpCas9	negative selection	11435791
155201146	155201169	1	-	28162770	EOL1	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	0.15795700829505033	[409]	[240]	1	hSpCas9	negative selection	11435792
155200489	155200512	1	-	28162770	EOL1	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.0360230584329741	[360]	[194]	0	hSpCas9	negative selection	11435793
155200038	155200061	1	-	28162770	EOL1	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	0.21827897462724488	[495]	[303]	2	hSpCas9	negative selection	11435794
155198574	155198597	1	-	28162770	EOL1	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	1.137277095556263	[213]	[247]	8	hSpCas9	negative selection	11435795
155198424	155198447	1	+	28162770	EOL1	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-0.3604291871439363	[211]	[86]	-3	hSpCas9	negative selection	11435796
155198134	155198157	1	-	28162770	EOL1	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.4631132887770041	[695]	[265]	-3	hSpCas9	negative selection	11435797
155197489	155197512	1	-	28162770	EOL1	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	0.05676296695960714	[322]	[176]	0	hSpCas9	negative selection	11435798
155207829	155207852	1	+	28162770	MOLM13	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-0.30891647715341836	[256]	[149]	-2	hSpCas9	negative selection	11605155
155196092	155196115	1	-	28162770	MOLM13	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	1.2112527469089356	[269]	[451]	8	hSpCas9	negative selection	11605156
155201524	155201547	1	+	28162770	MOLM13	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-1.6818577379601034	[70]	[15]	-7	hSpCas9	negative selection	11605157
155201146	155201169	1	-	28162770	MOLM13	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-0.09954319461900102	[408]	[275]	0	hSpCas9	negative selection	11605158
155200489	155200512	1	-	28162770	MOLM13	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.7430692172404618	[275]	[333]	5	hSpCas9	negative selection	11605159
155200038	155200061	1	-	28162770	MOLM13	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	0.43708333476340394	[283]	[277]	3	hSpCas9	negative selection	11605160
155198574	155198597	1	-	28162770	MOLM13	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	-0.15023998311177666	[263]	[171]	-1	hSpCas9	negative selection	11605161
155198424	155198447	1	+	28162770	MOLM13	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	1.2944065606890773	[202]	[359]	8	hSpCas9	negative selection	11605162
155198134	155198157	1	-	28162770	MOLM13	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-1.0356330596585206	[705]	[248]	-5	hSpCas9	negative selection	11605163
155197489	155197512	1	-	28162770	MOLM13	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-0.15359899520169132	[339]	[220]	-1	hSpCas9	negative selection	11605164
155207829	155207852	1	+	28162770	HEL	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-0.5694144048312528	[233]	[100]	-4	hSpCas9	negative selection	11774521
155196092	155196115	1	-	28162770	HEL	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	-0.2832605865558661	[265]	[139]	-2	hSpCas9	negative selection	11774522
155201524	155201547	1	+	28162770	HEL	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-2.2728689807092706	[82]	[10]	-8	hSpCas9	negative selection	11774523
155201146	155201169	1	-	28162770	HEL	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-0.5883602846869903	[276]	[117]	-4	hSpCas9	negative selection	11774524
155200489	155200512	1	-	28162770	HEL	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.14823128222470444	[254]	[180]	1	hSpCas9	negative selection	11774525
155200038	155200061	1	-	28162770	HEL	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	0.1583276296808509	[283]	[202]	1	hSpCas9	negative selection	11774526
155198574	155198597	1	-	28162770	HEL	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	-0.004245395328183632	[201]	[128]	0	hSpCas9	negative selection	11774527
155198424	155198447	1	+	28162770	HEL	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-0.802498905054186	[176]	[64]	-5	hSpCas9	negative selection	11774528
155198134	155198157	1	-	28162770	HEL	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.759531371204609	[599]	[226]	-5	hSpCas9	negative selection	11774529
155197489	155197512	1	-	28162770	HEL	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-1.6735205128003134	[253]	[50]	-7	hSpCas9	negative selection	11774530
155207829	155207852	1	+	28162770	MV411	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	0.39944064422782527	[116]	[129]	3	hSpCas9	negative selection	11943887
155196092	155196115	1	-	28162770	MV411	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	-0.11869034801512206	[173]	[134]	-1	hSpCas9	negative selection	11943888
155201524	155201547	1	+	28162770	MV411	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-0.4804829037804239	[52]	[31]	-4	hSpCas9	negative selection	11943889
155201146	155201169	1	-	28162770	MV411	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-0.9958336002295887	[231]	[97]	-6	hSpCas9	negative selection	11943890
155200489	155200512	1	-	28162770	MV411	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.36025738111708017	[208]	[225]	3	hSpCas9	negative selection	11943891
155200038	155200061	1	-	28162770	MV411	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-1.297723941880406	[285]	[97]	-7	hSpCas9	negative selection	11943892
155198574	155198597	1	-	28162770	MV411	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	0.272972642889913	[167]	[170]	2	hSpCas9	negative selection	11943893
155198424	155198447	1	+	28162770	MV411	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-1.2008362779700006	[160]	[58]	-7	hSpCas9	negative selection	11943894
155198134	155198157	1	-	28162770	MV411	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.24822926840574877	[508]	[360]	-2	hSpCas9	negative selection	11943895
155197489	155197512	1	-	28162770	MV411	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-1.6356063028713754	[224]	[60]	-7	hSpCas9	negative selection	11943896
155207829	155207852	1	+	28162770	MONOMAC1	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	0.3704382269327615	[82]	[122]	3	hSpCas9	negative selection	12113253
155196092	155196115	1	-	28162770	MONOMAC1	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	-0.5380737648946207	[132]	[104]	-4	hSpCas9	negative selection	12113254
155201524	155201547	1	+	28162770	MONOMAC1	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	-0.19703684705955382	[37]	[37]	-2	hSpCas9	negative selection	12113255
155201146	155201169	1	-	28162770	MONOMAC1	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-0.025765419909724772	[118]	[133]	0	hSpCas9	negative selection	12113256
155200489	155200512	1	-	28162770	MONOMAC1	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	-0.6910256877332195	[168]	[119]	-5	hSpCas9	negative selection	12113257
155200038	155200061	1	-	28162770	MONOMAC1	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-0.2935448279129001	[169]	[158]	-3	hSpCas9	negative selection	12113258
155198574	155198597	1	-	28162770	MONOMAC1	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	0.6971684889178495	[98]	[183]	6	hSpCas9	negative selection	12113259
155198424	155198447	1	+	28162770	MONOMAC1	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	0.8266144210050917	[120]	[245]	7	hSpCas9	negative selection	12113260
155198134	155198157	1	-	28162770	MONOMAC1	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-1.269793189494868	[365]	[173]	-7	hSpCas9	negative selection	12113261
155197489	155197512	1	-	28162770	MONOMAC1	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-0.30087265804409347	[143]	[133]	-3	hSpCas9	negative selection	12113262
155207829	155207852	1	+	28162770	OCIAML2	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	0.0699385561205416	[32]	[191]	0	hSpCas9	negative selection	12282619
155196092	155196115	1	-	28162770	OCIAML2	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	0.23363160385133921	[28]	[188]	2	hSpCas9	negative selection	12282620
155201524	155201547	1	+	28162770	OCIAML2	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	0.11433267547899495	[16]	[101]	1	hSpCas9	negative selection	12282621
155201146	155201169	1	-	28162770	OCIAML2	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	0.2646954105427894	[43]	[292]	2	hSpCas9	negative selection	12282622
155200489	155200512	1	-	28162770	OCIAML2	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	0.7898977249810578	[35]	[344]	7	hSpCas9	negative selection	12282623
155200038	155200061	1	-	28162770	OCIAML2	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	-0.5822751810710701	[46]	[173]	-4	hSpCas9	negative selection	12282624
155198574	155198597	1	-	28162770	OCIAML2	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	-0.5351700774368717	[39]	[152]	-4	hSpCas9	negative selection	12282625
155198424	155198447	1	+	28162770	OCIAML2	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-0.48456901620003506	[25]	[102]	-4	hSpCas9	negative selection	12282626
155198134	155198157	1	-	28162770	OCIAML2	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.25355904417390795	[96]	[450]	-2	hSpCas9	negative selection	12282627
155197489	155197512	1	-	28162770	OCIAML2	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	0.05509347210431889	[28]	[166]	0	hSpCas9	negative selection	12282628
155207829	155207852	1	+	28162770	OCIAML3	viability	GCAAAGGAGGAGAAGAGCCAGGG	THBS3	ENSG00000169231	-0.05514155419246095	[52]	[153]	0	hSpCas9	negative selection	12451985
155196092	155196115	1	-	28162770	OCIAML3	viability	TGAGGGACCCCAGCTTGTGGCGG	THBS3	ENSG00000169231	0.6966695205787594	[55]	[273]	6	hSpCas9	negative selection	12451986
155201524	155201547	1	+	28162770	OCIAML3	viability	GGTTGCCCAGGAAACCCAGGCGG	THBS3	ENSG00000169231	1.3401044240193796	[13]	[106]	9	hSpCas9	negative selection	12451987
155201146	155201169	1	-	28162770	OCIAML3	viability	GGGACTGACACAGACATCGATGG	THBS3	ENSG00000169231	-0.9863250631029234	[62]	[95]	-6	hSpCas9	negative selection	12451988
155200489	155200512	1	-	28162770	OCIAML3	viability	CAGAAGGACACAGATGGCAATGG	THBS3	ENSG00000169231	-0.3681262329078353	[58]	[137]	-3	hSpCas9	negative selection	12451989
155200038	155200061	1	-	28162770	OCIAML3	viability	GACAGGGATGAGGACGGGGTGGG	THBS3	ENSG00000169231	0.11074937293170761	[76]	[250]	1	hSpCas9	negative selection	12451990
155198574	155198597	1	-	28162770	OCIAML3	viability	GGATGGGCATCAGGACACCAAGG	THBS3	ENSG00000169231	0.7279204545631992	[69]	[349]	6	hSpCas9	negative selection	12451991
155198424	155198447	1	+	28162770	OCIAML3	viability	GATTGGGATTGGGTACCAGGCGG	THBS3	ENSG00000169231	-0.9967668098245701	[38]	[58]	-6	hSpCas9	negative selection	12451992
155198134	155198157	1	-	28162770	OCIAML3	viability	TGTGTGTCCTGAAAGTGCAGAGG	THBS3	ENSG00000169231	-0.2973906339659882	[137]	[338]	-2	hSpCas9	negative selection	12451993
155197489	155197512	1	-	28162770	OCIAML3	viability	GCAGGCTACACCCTTCCGGGCGG	THBS3	ENSG00000169231	-1.1345760216868659	[55]	[76]	-7	hSpCas9	negative selection	12451994