Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7072
• Symbol:TIA1
• Description:TIA1 cytotoxic granule associated RNA binding protein

DataSource: http://genomecrispr.dkfz.de/#!/results/TIA1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
70227793	70227816	2	+	26472758	Jiyoye	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	2.5771003829481858	[7]	[35]	9	hSpCas9	negative selection	165397
70215360	70215383	2	+	26472758	Jiyoye	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.9319508761519404	[154]	[222]	6	hSpCas9	negative selection	165398
70216963	70216986	2	-	26472758	Jiyoye	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	2.407175381505873	[41]	[167]	9	hSpCas9	negative selection	165399
70214452	70214475	2	+	26472758	Jiyoye	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	-0.7847364333758128	[280]	[122]	-5	hSpCas9	negative selection	165400
70214431	70214454	2	+	26472758	Jiyoye	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	0.7633191917311488	[124]	[159]	5	hSpCas9	negative selection	165401
70216427	70216450	2	-	26472758	Jiyoye	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	0.13664643912515517	[385]	[319]	1	hSpCas9	negative selection	165402
70248392	70248415	2	+	26472758	Jiyoye	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.4283399915039158	[202]	[205]	3	hSpCas9	negative selection	165403
70216891	70216914	2	+	26472758	Jiyoye	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.323111116717399	[52]	[49]	2	hSpCas9	negative selection	165404
70224604	70224627	2	-	26472758	Jiyoye	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	-0.45687712046492934	[252]	[138]	-3	hSpCas9	negative selection	165405
70224579	70224602	2	-	26472758	Jiyoye	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	1.2597450178506477	[174]	[315]	7	hSpCas9	negative selection	165406
70227793	70227816	2	+	26472758	KBM7	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	0.058824306911800406	[245,196]	[177,44]	0	hSpCas9	negative selection	356515
70215360	70215383	2	+	26472758	KBM7	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.5723515573391287	[1142,1217]	[585,1051]	6	hSpCas9	negative selection	356516
70216963	70216986	2	-	26472758	KBM7	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	-0.0051735355334772415	[392,472]	[162,243]	0	hSpCas9	negative selection	356517
70214452	70214475	2	+	26472758	KBM7	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	0.14793518406999268	[626,444]	[374,186]	1	hSpCas9	negative selection	356518
70214431	70214454	2	+	26472758	KBM7	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	1.2379780481727019	[630,506]	[672,585]	9	hSpCas9	negative selection	356519
70216427	70216450	2	-	26472758	KBM7	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	0.5630423976250282	[817,765]	[588,516]	6	hSpCas9	negative selection	356520
70248392	70248415	2	+	26472758	KBM7	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.7007153095218761	[872,921]	[905,498]	7	hSpCas9	negative selection	356521
70216891	70216914	2	+	26472758	KBM7	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.4122123489528895	[218,169]	[125,115]	4	hSpCas9	negative selection	356522
70224604	70224627	2	-	26472758	KBM7	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.9816878497475485	[465,516]	[526,401]	9	hSpCas9	negative selection	356523
70224579	70224602	2	-	26472758	KBM7	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	0.5151844703683928	[986,1113]	[822,615]	5	hSpCas9	negative selection	356524
70227793	70227816	2	+	26472758	Raji	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	1.5064794907834218	[90]	[59]	9	hSpCas9	negative selection	547633
70215360	70215383	2	+	26472758	Raji	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.5175716349910475	[595]	[197]	5	hSpCas9	negative selection	547634
70216963	70216986	2	-	26472758	Raji	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	-0.2571888969222567	[308]	[59]	-2	hSpCas9	negative selection	547635
70214452	70214475	2	+	26472758	Raji	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	0.956966692820501	[201]	[90]	8	hSpCas9	negative selection	547636
70214431	70214454	2	+	26472758	Raji	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	0.8958794301798877	[175]	[75]	7	hSpCas9	negative selection	547637
70216427	70216450	2	-	26472758	Raji	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	1.302070644854214	[352]	[201]	9	hSpCas9	negative selection	547638
70248392	70248415	2	+	26472758	Raji	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.43680060909915963	[537]	[168]	4	hSpCas9	negative selection	547639
70216891	70216914	2	+	26472758	Raji	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.6419657832484393	[194]	[28]	-5	hSpCas9	negative selection	547640
70224604	70224627	2	-	26472758	Raji	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	-0.4691173865993606	[339]	[56]	-4	hSpCas9	negative selection	547641
70224579	70224602	2	-	26472758	Raji	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	-0.35204808326369774	[582]	[105]	-3	hSpCas9	negative selection	547642
70227793	70227816	2	+	26472758	K562	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	-0.06315407424384567	[124]	[100]	0	hSpCas9	negative selection	738751
70215360	70215383	2	+	26472758	K562	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.7405641484023529	[976]	[1377]	6	hSpCas9	negative selection	738752
70216963	70216986	2	-	26472758	K562	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	0.296632932107385	[406]	[421]	2	hSpCas9	negative selection	738753
70214452	70214475	2	+	26472758	K562	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	-0.6582840709786384	[601]	[321]	-4	hSpCas9	negative selection	738754
70214431	70214454	2	+	26472758	K562	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	0.09462714572117586	[506]	[456]	0	hSpCas9	negative selection	738755
70216427	70216450	2	-	26472758	K562	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	-0.1238957154328193	[718]	[556]	-1	hSpCas9	negative selection	738756
70248392	70248415	2	+	26472758	K562	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.8698889524929776	[795]	[1227]	7	hSpCas9	negative selection	738757
70216891	70216914	2	+	26472758	K562	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.5185936911054411	[171]	[207]	4	hSpCas9	negative selection	738758
70224604	70224627	2	-	26472758	K562	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.8092530268866549	[408]	[604]	6	hSpCas9	negative selection	738759
70224579	70224602	2	-	26472758	K562	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	0.3187370483562806	[907]	[955]	2	hSpCas9	negative selection	738760
70214371	70214394	2	-	26627737	DLD1	viability	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	-1.0079789124889902	[565]	[168,106,1]	-7	hSpCas9	negative selection	812495
70215360	70215383	2	+	26627737	DLD1	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-0.6532954558342841	[720]	[250,71,108]	-6	hSpCas9	negative selection	812496
70216891	70216914	2	+	26627737	DLD1	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.22089854002391696	[213]	[57,49,62]	-2	hSpCas9	negative selection	812497
70224616	70224639	2	-	26627737	DLD1	viability	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.47016643139657627	[394]	[159,236,125]	5	hSpCas9	negative selection	812498
70225343	70225366	2	+	26627737	DLD1	viability	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.9339548482373673	[732]	[460,394,452]	8	hSpCas9	negative selection	812499
70229063	70229086	2	+	26627737	DLD1	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.08594044035688875	[839]	[348,246,243]	0	hSpCas9	negative selection	812500
70214371	70214394	2	-	26627737	GBM cells	viability after 5 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	0.8051994400634919	[158]	[161,135]	9	hSpCas9	negative selection	894810
70215360	70215383	2	+	26627737	GBM cells	viability after 5 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-0.45102859617127333	[259]	[121,81]	-6	hSpCas9	negative selection	894811
70216891	70216914	2	+	26627737	GBM cells	viability after 5 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.3158249739073271	[93]	[32,47]	-5	hSpCas9	negative selection	894812
70224616	70224639	2	-	26627737	GBM cells	viability after 5 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	-0.6716933328584005	[299]	[89,111]	-8	hSpCas9	negative selection	894813
70225343	70225366	2	+	26627737	GBM cells	viability after 5 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.34674130928219893	[521]	[395,315]	5	hSpCas9	negative selection	894814
70229063	70229086	2	+	26627737	GBM cells	viability after 5 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.2957713580995085	[558]	[337,397]	4	hSpCas9	negative selection	894815
70214371	70214394	2	-	26627737	GBM cells	viability after 13 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	0.8583575659908991	[158]	[210,111]	8	hSpCas9	negative selection	977125
70215360	70215383	2	+	26627737	GBM cells	viability after 13 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-0.24696315858944357	[259]	[146,95]	-3	hSpCas9	negative selection	977126
70216891	70216914	2	+	26627737	GBM cells	viability after 13 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.1221916239373857	[93]	[42,49]	-1	hSpCas9	negative selection	977127
70224616	70224639	2	-	26627737	GBM cells	viability after 13 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	-0.6239080357478866	[299]	[114,97]	-6	hSpCas9	negative selection	977128
70225343	70225366	2	+	26627737	GBM cells	viability after 13 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.5036910743858332	[521]	[357,436]	6	hSpCas9	negative selection	977129
70229063	70229086	2	+	26627737	GBM cells	viability after 13 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.49966364605642344	[558]	[435,422]	6	hSpCas9	negative selection	977130
70214371	70214394	2	-	26627737	GBM cells	viability after 21 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	0.30641833613952396	[158]	[110,102]	3	hSpCas9	negative selection	1059440
70215360	70215383	2	+	26627737	GBM cells	viability after 21 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-1.1648545899128797	[259]	[62,62]	-7	hSpCas9	negative selection	1059441
70216891	70216914	2	+	26627737	GBM cells	viability after 21 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.45798691835330096	[93]	[32,40]	-4	hSpCas9	negative selection	1059442
70224616	70224639	2	-	26627737	GBM cells	viability after 21 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	-0.8869695249810494	[299]	[84,90]	-6	hSpCas9	negative selection	1059443
70225343	70225366	2	+	26627737	GBM cells	viability after 21 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.7322168248263328	[521]	[503,440]	7	hSpCas9	negative selection	1059444
70229063	70229086	2	+	26627737	GBM cells	viability after 21 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.4683085770093649	[558]	[439,401]	5	hSpCas9	negative selection	1059445
70214371	70214394	2	-	26627737	RPE1	viability after 9 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	-2.32041184185161	[1165]	[21,138]	-9	hSpCas9	negative selection	1141755
70215360	70215383	2	+	26627737	RPE1	viability after 9 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-1.1448634430638551	[823]	[134,92]	-7	hSpCas9	negative selection	1141756
70216891	70216914	2	+	26627737	RPE1	viability after 9 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.5260126476203673	[441]	[82,112]	-4	hSpCas9	negative selection	1141757
70224616	70224639	2	-	26627737	RPE1	viability after 9 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.9703221146589954	[680]	[525,277]	6	hSpCas9	negative selection	1141758
70225343	70225366	2	+	26627737	RPE1	viability after 9 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	1.9107880516384141	[866]	[738,1383]	8	hSpCas9	negative selection	1141759
70229063	70229086	2	+	26627737	RPE1	viability after 9 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.8285718197101108	[1447]	[777,839]	5	hSpCas9	negative selection	1141760
70214371	70214394	2	-	26627737	RPE1	viability after 12 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	-3.590800943386266	[1165]	[8,43]	-9	hSpCas9	negative selection	1224070
70215360	70215383	2	+	26627737	RPE1	viability after 12 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-0.9053028902199105	[823]	[124,110]	-6	hSpCas9	negative selection	1224071
70216891	70216914	2	+	26627737	RPE1	viability after 12 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.6856838099693352	[441]	[101,43]	-5	hSpCas9	negative selection	1224072
70224616	70224639	2	-	26627737	RPE1	viability after 12 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.6810444764522656	[680]	[406,172]	4	hSpCas9	negative selection	1224073
70225343	70225366	2	+	26627737	RPE1	viability after 12 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	1.9193617932851983	[866]	[713,1057]	8	hSpCas9	negative selection	1224074
70229063	70229086	2	+	26627737	RPE1	viability after 12 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.8928054834606391	[1447]	[733,709]	5	hSpCas9	negative selection	1224075
70214371	70214394	2	-	26627737	RPE1	viability after 15 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	-2.978268108428997	[1165]	[49,33]	-9	hSpCas9	negative selection	1306385
70215360	70215383	2	+	26627737	RPE1	viability after 15 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-0.9087665081746357	[823]	[227,23]	-5	hSpCas9	negative selection	1306386
70216891	70216914	2	+	26627737	RPE1	viability after 15 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.08679542416025454	[441]	[172,93]	0	hSpCas9	negative selection	1306387
70224616	70224639	2	-	26627737	RPE1	viability after 15 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.8350881730507314	[680]	[446,243]	5	hSpCas9	negative selection	1306388
70225343	70225366	2	+	26627737	RPE1	viability after 15 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	1.8960242540133985	[866]	[979,847]	8	hSpCas9	negative selection	1306389
70229063	70229086	2	+	26627737	RPE1	viability after 15 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.6861218400541338	[1447]	[684,633]	4	hSpCas9	negative selection	1306390
70214371	70214394	2	-	26627737	RPE1	viability after 18 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	-8.297683813099754	[1165]	[0,0]	-9	hSpCas9	negative selection	1388700
70215360	70215383	2	+	26627737	RPE1	viability after 18 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-1.6691129354724226	[823]	[23,118]	-7	hSpCas9	negative selection	1388701
70216891	70216914	2	+	26627737	RPE1	viability after 18 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.22313010585618143	[441]	[165,33]	-1	hSpCas9	negative selection	1388702
70224616	70224639	2	-	26627737	RPE1	viability after 18 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.7040100351492552	[680]	[397,193]	4	hSpCas9	negative selection	1388703
70225343	70225366	2	+	26627737	RPE1	viability after 18 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	1.7881354090101056	[866]	[620,1007]	8	hSpCas9	negative selection	1388704
70229063	70229086	2	+	26627737	RPE1	viability after 18 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.7110344981573433	[1447]	[746,524]	4	hSpCas9	negative selection	1388705
70214371	70214394	2	-	26627737	HeLa	viability after 8 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	2.1018484802164306	[36]	[163,65,2]	9	hSpCas9	negative selection	1471015
70215360	70215383	2	+	26627737	HeLa	viability after 8 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.0647190962384514	[150]	[144,9,67]	0	hSpCas9	negative selection	1471016
70216891	70216914	2	+	26627737	HeLa	viability after 8 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.7631522896924938	[259]	[120,39,51]	-6	hSpCas9	negative selection	1471017
70224616	70224639	2	-	26627737	HeLa	viability after 8 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	1.065766009202698	[171]	[126,157,176]	7	hSpCas9	negative selection	1471018
70225343	70225366	2	+	26627737	HeLa	viability after 8 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	-0.20386207575827187	[1122]	[610,472,242]	-2	hSpCas9	negative selection	1471019
70229063	70229086	2	+	26627737	HeLa	viability after 8 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.03836396744289616	[958]	[453,568,219]	0	hSpCas9	negative selection	1471020
70214371	70214394	2	-	26627737	HeLa	viability after 12 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	2.978520832692623	[36]	[129,33,206]	9	hSpCas9	negative selection	1553330
70215360	70215383	2	+	26627737	HeLa	viability after 12 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.7130862688726941	[150]	[64,175,56]	6	hSpCas9	negative selection	1553331
70216891	70216914	2	+	26627737	HeLa	viability after 12 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.40548400463544176	[259]	[137,52,56]	-4	hSpCas9	negative selection	1553332
70224616	70224639	2	-	26627737	HeLa	viability after 12 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	1.3502821141145835	[171]	[284,102,166]	8	hSpCas9	negative selection	1553333
70225343	70225366	2	+	26627737	HeLa	viability after 12 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	-0.18859247166031068	[1122]	[440,488,283]	-2	hSpCas9	negative selection	1553334
70229063	70229086	2	+	26627737	HeLa	viability after 12 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.5896582928408391	[958]	[320,175,303]	-5	hSpCas9	negative selection	1553335
70214371	70214394	2	-	26627737	HeLa	viability after 15 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	2.5233404171588383	[36]	[72,99,86]	9	hSpCas9	negative selection	1635645
70215360	70215383	2	+	26627737	HeLa	viability after 15 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	1.8813352858068795	[150]	[127,237,321]	9	hSpCas9	negative selection	1635646
70216891	70216914	2	+	26627737	HeLa	viability after 15 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-1.4184203009710334	[259]	[19,47,51]	-8	hSpCas9	negative selection	1635647
70224616	70224639	2	-	26627737	HeLa	viability after 15 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.3941545466739099	[171]	[72,114,87]	3	hSpCas9	negative selection	1635648
70225343	70225366	2	+	26627737	HeLa	viability after 15 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.5629756036990103	[1122]	[723,656,641]	4	hSpCas9	negative selection	1635649
70229063	70229086	2	+	26627737	HeLa	viability after 15 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.5508546488053565	[958]	[251,204,348]	-5	hSpCas9	negative selection	1635650
70214371	70214394	2	-	26627737	HeLa	viability after 18 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	2.5145547207298127	[36]	[42,88,86]	9	hSpCas9	negative selection	1717960
70215360	70215383	2	+	26627737	HeLa	viability after 18 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	1.8723342364651259	[150]	[83,195,321]	9	hSpCas9	negative selection	1717961
70216891	70216914	2	+	26627737	HeLa	viability after 18 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-1.3708084753624612	[259]	[14,40,51]	-8	hSpCas9	negative selection	1717962
70224616	70224639	2	-	26627737	HeLa	viability after 18 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.44826556221467684	[171]	[51,99,87]	3	hSpCas9	negative selection	1717963
70225343	70225366	2	+	26627737	HeLa	viability after 18 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.5693409063849486	[1122]	[477,560,641]	4	hSpCas9	negative selection	1717964
70229063	70229086	2	+	26627737	HeLa	viability after 18 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.5633770488015064	[958]	[157,177,348]	-5	hSpCas9	negative selection	1717965
70214371	70214394	2	-	26627737	HCT116	viability after 6 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	-0.8874359457982566	[857]	[50,84]	-5	hSpCas9	negative selection	1800275
70215360	70215383	2	+	26627737	HCT116	viability after 6 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	1.7183655744924922	[346]	[203,165]	8	hSpCas9	negative selection	1800276
70216891	70216914	2	+	26627737	HCT116	viability after 6 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	2.1966816734188113	[175]	[24,182]	9	hSpCas9	negative selection	1800277
70224616	70224639	2	-	26627737	HCT116	viability after 6 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	-0.9264354116111574	[648]	[92,31]	-5	hSpCas9	negative selection	1800278
70225343	70225366	2	+	26627737	HCT116	viability after 6 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.6974666415221755	[1500]	[294,430]	4	hSpCas9	negative selection	1800279
70229063	70229086	2	+	26627737	HCT116	viability after 6 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.614214820935457	[969]	[371,156]	3	hSpCas9	negative selection	1800280
70214371	70214394	2	-	26627737	HCT116	viability after 8 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	-0.04637765972829366	[247]	[117,167,110]	0	hSpCas9	negative selection	1882590
70215360	70215383	2	+	26627737	HCT116	viability after 8 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	2.866768315070406	[21]	[73,100,89]	9	hSpCas9	negative selection	1882591
70216891	70216914	2	+	26627737	HCT116	viability after 8 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.4319176008264285	[134]	[71,60,32]	-5	hSpCas9	negative selection	1882592
70224616	70224639	2	-	26627737	HCT116	viability after 8 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.3382791533119741	[262]	[213,136,198]	3	hSpCas9	negative selection	1882593
70225343	70225366	2	+	26627737	HCT116	viability after 8 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.18333390881570777	[619]	[428,386,348]	2	hSpCas9	negative selection	1882594
70229063	70229086	2	+	26627737	HCT116	viability after 8 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.1511918575973059	[753]	[426,457,239]	-2	hSpCas9	negative selection	1882595
70214371	70214394	2	-	26627737	HCT116	viability after 9 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	0.1534386514751408	[857]	[475,79]	1	hSpCas9	negative selection	1964905
70215360	70215383	2	+	26627737	HCT116	viability after 9 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	2.119123657795779	[346]	[201,560]	9	hSpCas9	negative selection	1964906
70216891	70216914	2	+	26627737	HCT116	viability after 9 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.4498166251928941	[175]	[28,91]	3	hSpCas9	negative selection	1964907
70224616	70224639	2	-	26627737	HCT116	viability after 9 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.003615991400474153	[648]	[347,35]	0	hSpCas9	negative selection	1964908
70225343	70225366	2	+	26627737	HCT116	viability after 9 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	-0.3992613088197323	[1500]	[466,174]	-3	hSpCas9	negative selection	1964909
70229063	70229086	2	+	26627737	HCT116	viability after 9 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.44217427158714173	[969]	[452,271]	3	hSpCas9	negative selection	1964910
70214371	70214394	2	-	26627737	HCT116	viability after 12 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	0.024194742437302463	[247]	[91,166,142]	0	hSpCas9	negative selection	2047220
70215360	70215383	2	+	26627737	HCT116	viability after 12 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	3.1883129978668814	[21]	[89,83,142]	9	hSpCas9	negative selection	2047221
70216891	70216914	2	+	26627737	HCT116	viability after 12 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.24523327819344498	[134]	[49,41,87]	-3	hSpCas9	negative selection	2047222
70224616	70224639	2	-	26627737	HCT116	viability after 12 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.18520972387374254	[262]	[170,147,150]	2	hSpCas9	negative selection	2047223
70225343	70225366	2	+	26627737	HCT116	viability after 12 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.12257911223468976	[619]	[479,306,264]	1	hSpCas9	negative selection	2047224
70229063	70229086	2	+	26627737	HCT116	viability after 12 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.0801151464377019	[753]	[322,453,353]	-1	hSpCas9	negative selection	2047225
70214371	70214394	2	-	26627737	HCT116	viability after 15 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	0.24013650310207033	[247]	[256,217,41]	2	hSpCas9	negative selection	2129535
70215360	70215383	2	+	26627737	HCT116	viability after 15 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	3.2380260386964523	[21]	[117,80,157]	9	hSpCas9	negative selection	2129536
70216891	70216914	2	+	26627737	HCT116	viability after 15 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.08188289409605387	[134]	[59,72,84]	-1	hSpCas9	negative selection	2129537
70224616	70224639	2	-	26627737	HCT116	viability after 15 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.005258126733664131	[262]	[201,114,143]	0	hSpCas9	negative selection	2129538
70225343	70225366	2	+	26627737	HCT116	viability after 15 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.4687314945445227	[619]	[554,534,396]	4	hSpCas9	negative selection	2129539
70229063	70229086	2	+	26627737	HCT116	viability after 15 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.2852321246860634	[753]	[322,459,279]	-3	hSpCas9	negative selection	2129540
70214371	70214394	2	-	26627737	HCT116	viability after 18 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	-0.3953817098080466	[247]	[149,70,51]	-4	hSpCas9	negative selection	2211850
70215360	70215383	2	+	26627737	HCT116	viability after 18 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	3.421478082448148	[21]	[51,163,122]	9	hSpCas9	negative selection	2211851
70216891	70216914	2	+	26627737	HCT116	viability after 18 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.45935212234656786	[134]	[97,70,101]	4	hSpCas9	negative selection	2211852
70224616	70224639	2	-	26627737	HCT116	viability after 18 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	-0.18827359085260664	[262]	[136,64,136]	-2	hSpCas9	negative selection	2211853
70225343	70225366	2	+	26627737	HCT116	viability after 18 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.5706402170323357	[619]	[315,493,525]	5	hSpCas9	negative selection	2211854
70229063	70229086	2	+	26627737	HCT116	viability after 18 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.3449399902769985	[753]	[486,503,391]	3	hSpCas9	negative selection	2211855
70227801	70227824	2	-	24336569	HL60	viability	GATCATTTCCATGTCTTTGTTGG	TIA1	ENSG00000116001	0.8606011302869622	[234]	[902]	7	hSpCas9	negative selection	2300392
70229300	70229323	2	-	24336569	HL60	viability	TTAGGAAGTCAAAGTGAATTGGG	TIA1	ENSG00000116001	-0.47723157297742314	[470]	[715]	-4	hSpCas9	negative selection	2300393
70230755	70230778	2	-	24336569	HL60	viability	TGGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	0.3539370297336827	[808]	[2187]	3	hSpCas9	negative selection	2300394
70230760	70230783	2	-	24336569	HL60	viability	ATGAATGGACGGAAGATAATGGG	TIA1	ENSG00000116001	-0.5035494646369927	[1367]	[2041]	-4	hSpCas9	negative selection	2300395
70230771	70230794	2	-	24336569	HL60	viability	CATTAGCTGCTATGAATGGACGG	TIA1	ENSG00000116001	1.2769059902265263	[257]	[1322]	8	hSpCas9	negative selection	2300396
70230847	70230870	2	-	24336569	HL60	viability	TTTCTTCTCCCACAGACAGCTGG	TIA1	ENSG00000116001	-0.6502576644565411	[243]	[328]	-5	hSpCas9	negative selection	2300397
70236110	70236133	2	-	24336569	HL60	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.146804887044221	[489]	[1147]	1	hSpCas9	negative selection	2300398
70236136	70236159	2	+	24336569	HL60	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.1254074482164933	[749]	[1454]	-1	hSpCas9	negative selection	2300399
70236167	70236190	2	-	24336569	HL60	viability	TCTTTGTGTTTCAGATACGTCGG	TIA1	ENSG00000116001	0.537541863619224	[348]	[1071]	5	hSpCas9	negative selection	2300400
70248410	70248433	2	+	24336569	HL60	viability	CTTGGGCATCTCGTCCTCCATGG	TIA1	ENSG00000116001	0.8135328163983688	[405]	[1509]	6	hSpCas9	negative selection	2300401
70227801	70227824	2	-	24336569	KBM7	viability	GATCATTTCCATGTCTTTGTTGG	TIA1	ENSG00000116001	0.7283445455148728	[319]	[1445]	6	hSpCas9	negative selection	2367569
70229300	70229323	2	-	24336569	KBM7	viability	TTAGGAAGTCAAAGTGAATTGGG	TIA1	ENSG00000116001	1.2032712398287309	[320]	[2015]	8	hSpCas9	negative selection	2367570
70230755	70230778	2	-	24336569	KBM7	viability	TGGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	0.5429535763550796	[687]	[2733]	5	hSpCas9	negative selection	2367571
70230760	70230783	2	-	24336569	KBM7	viability	ATGAATGGACGGAAGATAATGGG	TIA1	ENSG00000116001	0.5860515813323977	[582]	[2386]	5	hSpCas9	negative selection	2367572
70230771	70230794	2	-	24336569	KBM7	viability	CATTAGCTGCTATGAATGGACGG	TIA1	ENSG00000116001	-0.3786445650659767	[377]	[792]	-3	hSpCas9	negative selection	2367573
70230847	70230870	2	-	24336569	KBM7	viability	TTTCTTCTCCCACAGACAGCTGG	TIA1	ENSG00000116001	1.0919403334111069	[214]	[1249]	8	hSpCas9	negative selection	2367574
70236110	70236133	2	-	24336569	KBM7	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.755974966346806	[456]	[2104]	6	hSpCas9	negative selection	2367575
70236136	70236159	2	+	24336569	KBM7	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	0.05095005685733689	[641]	[1813]	0	hSpCas9	negative selection	2367576
70236167	70236190	2	-	24336569	KBM7	viability	TCTTTGTGTTTCAGATACGTCGG	TIA1	ENSG00000116001	-0.6106178124059547	[626]	[1119]	-5	hSpCas9	negative selection	2367577
70248410	70248433	2	+	24336569	KBM7	viability	CTTGGGCATCTCGTCCTCCATGG	TIA1	ENSG00000116001	0.06819350107333794	[540]	[1546]	0	hSpCas9	negative selection	2367578
70239141	70239164	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGCGTGATCTCGG	TIA1	ENSG00000116001	1.5299201678265226	[5,69]	[1,47]	6	dCas9-VP64	positive selection	2386479
70233516	70233539	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAAGCTGGGG	TIA1	ENSG00000116001	4.479776146187553	[3,10]	[5,71]	9	dCas9-VP64	positive selection	2414969
70239141	70239164	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGCGTGATCTCGG	TIA1	ENSG00000116001	0.46408056547853904	[52,55]	[23,24]	3	dCas9-VP64	positive selection	2481734
70233516	70233539	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAAGCTGGGG	TIA1	ENSG00000116001	1.4055177615841226	[19,51]	[4,54]	7	dCas9-VP64	positive selection	2510224
70230771	70230794	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATTAGCTGCTATGAATGGACGG	TIA1	ENSG00000116001	0.3282520423204858	[2,2]	[2,3]	7	hSpCas9	positive selection	3026742
70216892	70216915	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.08827005311593078	[4,4]	[3,4]	1	hSpCas9	positive selection	3026743
70236167	70236190	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTTGTGTTTCAGATACGTCGG	TIA1	ENSG00000116001	0.25371784169004696	[3,3]	[4,3]	5	hSpCas9	positive selection	3026744
70230818	70230841	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAAACTCCACAAAACAATAGGG	TIA1	ENSG00000116001	-0.2519170605100331	[3,3]	[4,0]	-4	hSpCas9	positive selection	3026745
70230771	70230794	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATTAGCTGCTATGAATGGACGG	TIA1	ENSG00000116001	-0.265138781263873	[2,2]	[3,0]	-4	hSpCas9	positive selection	3094600
70216892	70216915	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.3315522698713468	[4,4]	[4,3]	6	hSpCas9	positive selection	3094601
70236167	70236190	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTTGTGTTTCAGATACGTCGG	TIA1	ENSG00000116001	-0.25315963673914843	[3,3]	[2,1]	-4	hSpCas9	positive selection	3094602
70230818	70230841	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAAACTCCACAAAACAATAGGG	TIA1	ENSG00000116001	0.21392483667529139	[3,3]	[3,2]	4	hSpCas9	positive selection	3094603
70230824	70230847		-	24336571	A375	resistance to PLX after 7 days	AAATGATCCCTATTGTTTTGTGG	TIA1	ENSG00000116001	0.0032894460680110704	[28,29]	[28,28]	0	hSpCas9	positive selection	3150245
70230816	70230839		+	24336571	A375	resistance to PLX after 7 days	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.5040295308124242	[6,6]	[10,9]	9	hSpCas9	positive selection	3150247
70236110	70236133		-	24336571	A375	resistance to PLX after 7 days	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	-0.07796454145949705	[22,22]	[20,21]	-2	hSpCas9	positive selection	3150248
70230824	70230847		-	24336571	A375	resistance to PLX after 14 days	AAATGATCCCTATTGTTTTGTGG	TIA1	ENSG00000116001	-0.2835545420597092	[27,32]	[12,8]	-3	hSpCas9	positive selection	3208038
70230816	70230839		+	24336571	A375	resistance to PLX after 14 days	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.3775852565389438	[7,7]	[3,4]	3	hSpCas9	positive selection	3208040
70236110	70236133		-	24336571	A375	resistance to PLX after 14 days	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.24984326066777163	[22,18]	[9,12]	2	hSpCas9	positive selection	3208041
70230824	70230847		-	24336571	A375	viability after 7 days	AAATGATCCCTATTGTTTTGTGG	TIA1	ENSG00000116001	0.4443307329260767	[21]	[28,29]	6	hSpCas9	negative selection	3265831
70230816	70230839		+	24336571	A375	viability after 7 days	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-1.4552051130351789	[21]	[6,6]	-9	hSpCas9	negative selection	3265833
70236110	70236133		-	24336571	A375	viability after 7 days	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.3883427994107774	[17]	[22,22]	6	hSpCas9	negative selection	3265834
70230824	70230847		-	24336571	A375	viability after 14 days	AAATGATCCCTATTGTTTTGTGG	TIA1	ENSG00000116001	0.5206024244030444	[21]	[27,32]	6	hSpCas9	negative selection	3323624
70230816	70230839		+	24336571	A375	viability after 14 days	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-1.2958921789377038	[21]	[7,7]	-9	hSpCas9	negative selection	3323626
70236110	70236133		-	24336571	A375	viability after 14 days	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.30930195803359045	[17]	[22,18]	4	hSpCas9	negative selection	3323627
70236136	70236159	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.4841407749553118	[213,213]	[0,0]	-3	hSpCas9	positive selection	3397148
70230775	70230798	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	-0.556454979771202	[224,224]	[0,0]	-4	hSpCas9	positive selection	3397149
70230816	70230839	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.3647256080105413	[196,196]	[0,0]	-2	hSpCas9	positive selection	3397150
70230771	70230794	2	-	26780180	HT29	viability (Avana library 4 designs)	CATTAGCTGCTATGAATGGACGG	TIA1	ENSG00000116001	0.508036521755342	[]	[]	2	hSpCas9	negative selection	3465483
70216891	70216914	2	+	26780180	HT29	viability (Avana library 4 designs)	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.258399848284901	[]	[]	0	hSpCas9	negative selection	3465484
70236167	70236190	2	-	26780180	HT29	viability (Avana library 4 designs)	TCTTTGTGTTTCAGATACGTCGG	TIA1	ENSG00000116001	1.4080369796218	[]	[]	5	hSpCas9	negative selection	3465485
70230817	70230840	2	+	26780180	HT29	viability (Avana library 4 designs)	TGAAACTCCACAAAACAATAGGG	TIA1	ENSG00000116001	-0.0240637055440074	[]	[]	0	hSpCas9	negative selection	3465486
70236167	70236190	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTTGTGTTTCAGATACGTCGG	TIA1	ENSG00000116001	-6.4732864425414	[]	[]	-6	hSpCas9	negative selection	3568697
70216891	70216914	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	1.95427084325735	[]	[]	3	hSpCas9	negative selection	3568698
70230817	70230840	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAACTCCACAAAACAATAGGG	TIA1	ENSG00000116001	-13.4857278751735	[]	[]	-8	hSpCas9	negative selection	3568699
70230771	70230794	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATTAGCTGCTATGAATGGACGG	TIA1	ENSG00000116001	2.72259766042626	[]	[]	4	hSpCas9	negative selection	3568700
70230760	70230783	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGAATGGACGGAAGATAATGGG	TIA1	ENSG00000116001	-0.0675837090947153	[]	[]	0	hSpCas9	negative selection	3568701
70216940	70216963	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGTCTTCCACCAAGCCACTGG	TIA1	ENSG00000116001	-1.0025642765985	[]	[]	-1	hSpCas9	negative selection	3568702
70236167	70236190	2	-	26780180	A375	viability (Avana lentiGuide)	TCTTTGTGTTTCAGATACGTCGG	TIA1	ENSG00000116001	2.37665401651307	[]	[]	2	hSpCas9	negative selection	3677356
70216891	70216914	2	+	26780180	A375	viability (Avana lentiGuide)	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.749346187496744	[]	[]	-1	hSpCas9	negative selection	3677357
70230817	70230840	2	+	26780180	A375	viability (Avana lentiGuide)	TGAAACTCCACAAAACAATAGGG	TIA1	ENSG00000116001	-4.64635797514859	[]	[]	-7	hSpCas9	negative selection	3677358
70230771	70230794	2	-	26780180	A375	viability (Avana lentiGuide)	CATTAGCTGCTATGAATGGACGG	TIA1	ENSG00000116001	5.66221075155572	[]	[]	5	hSpCas9	negative selection	3677359
70230760	70230783	2	-	26780180	A375	viability (Avana lentiGuide)	ATGAATGGACGGAAGATAATGGG	TIA1	ENSG00000116001	-4.05543923539586	[]	[]	-7	hSpCas9	negative selection	3677360
70216940	70216963	2	+	26780180	A375	viability (Avana lentiGuide)	TTTGTCTTCCACCAAGCCACTGG	TIA1	ENSG00000116001	-0.683199748425703	[]	[]	-1	hSpCas9	negative selection	3677361
70236167	70236190	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTTGTGTTTCAGATACGTCGG	TIA1	ENSG00000116001	-0.639359428931024	[6]	[3,3]	-7	hSpCas9	positive selection	3785963
70216891	70216914	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.15354649992336156	[6]	[7,6]	4	hSpCas9	positive selection	3785964
70230817	70230840	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAACTCCACAAAACAATAGGG	TIA1	ENSG00000116001	-1.2913405282367836	[6]	[2,1]	-9	hSpCas9	positive selection	3785965
70230771	70230794	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTAGCTGCTATGAATGGACGG	TIA1	ENSG00000116001	-0.00013702705266082152	[4]	[5,4]	0	hSpCas9	positive selection	3785966
70230760	70230783	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGAATGGACGGAAGATAATGGG	TIA1	ENSG00000116001	-0.07063183946507995	[7]	[6,6]	-1	hSpCas9	positive selection	3785967
70216940	70216963	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGTCTTCCACCAAGCCACTGG	TIA1	ENSG00000116001	-0.09594380176007307	[5]	[5,4]	-1	hSpCas9	positive selection	3785968
70236167	70236190	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTTGTGTTTCAGATACGTCGG	TIA1	ENSG00000116001	-0.21327943257395748	[6]	[3,5]	-3	hSpCas9	positive selection	3894570
70216891	70216914	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.06933050179207256	[6]	[6,5]	1	hSpCas9	positive selection	3894571
70230817	70230840	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAACTCCACAAAACAATAGGG	TIA1	ENSG00000116001	0.37683772217780187	[5]	[6,5]	9	hSpCas9	positive selection	3894572
70230771	70230794	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTAGCTGCTATGAATGGACGG	TIA1	ENSG00000116001	0.0660760843437132	[4]	[5,1]	1	hSpCas9	positive selection	3894573
70230760	70230783	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGAATGGACGGAAGATAATGGG	TIA1	ENSG00000116001	0.26051771695588966	[6]	[7,6]	7	hSpCas9	positive selection	3894574
70216940	70216963	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGTCTTCCACCAAGCCACTGG	TIA1	ENSG00000116001	0.054378852508317324	[5]	[5,4]	1	hSpCas9	positive selection	3894575
70230816	70230839	2	+	26780180	A375	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.738141801071893	[]	[]	2	hSpCas9	negative selection	4003926
70236110	70236133	2	-	26780180	A375	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.597725201070955	[]	[]	1	hSpCas9	negative selection	4003927
70230775	70230798	2	-	26780180	A375	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.97458255178404	[]	[]	4	hSpCas9	negative selection	4003928
70229058	70229081	2	-	26780180	A375	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.988933829256159	[]	[]	4	hSpCas9	negative selection	4003929
70236136	70236159	2	+	26780180	A375	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	1.1900169381007	[]	[]	6	hSpCas9	negative selection	4003930
70229063	70229086	2	+	26780180	A375	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	1.02885612883971	[]	[]	5	hSpCas9	negative selection	4003931
70230816	70230839	2	+	26780180	HT29	viability (GeCKOv2 library)	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	1.6725509236386	[]	[]	8	hSpCas9	negative selection	4111892
70236110	70236133	2	-	26780180	HT29	viability (GeCKOv2 library)	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	-0.276285837476339	[]	[]	-7	hSpCas9	negative selection	4111893
70230775	70230798	2	-	26780180	HT29	viability (GeCKOv2 library)	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.918163259589255	[]	[]	4	hSpCas9	negative selection	4111894
70229058	70229081	2	-	26780180	HT29	viability (GeCKOv2 library)	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.847214616691313	[]	[]	3	hSpCas9	negative selection	4111895
70236136	70236159	2	+	26780180	HT29	viability (GeCKOv2 library)	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	0.912110303845861	[]	[]	4	hSpCas9	negative selection	4111896
70229063	70229086	2	+	26780180	HT29	viability (GeCKOv2 library)	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.887490269471959	[]	[]	4	hSpCas9	negative selection	4111897
70230824	70230847	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAATGATCCCTATTGTTTTGTGG	TIA1	ENSG00000116001	0.21148278717946514	[4]	[3,3]	5	hSpCas9	positive selection	4176637
70230816	70230839	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.07176350760144888	[3]	[1,2]	-2	hSpCas9	positive selection	4176639
70236110	70236133	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.26958912538697527	[4]	[4,3]	6	hSpCas9	positive selection	4176640
70230824	70230847	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAATGATCCCTATTGTTTTGTGG	TIA1	ENSG00000116001	-0.014102133519107135	[4]	[0,4,3,0]	0	hSpCas9	positive selection	4240659
70230816	70230839	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.9826130253249503	[4]	[1,0,4,4]	7	hSpCas9	positive selection	4240661
70236110	70236133	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	1.0221963385562347	[4]	[1,3,4,5]	7	hSpCas9	positive selection	4240662
70229063	70229086	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.46554406191209985	[2]	[1,3]	8	hSpCas9	positive selection	4303051
70236110	70236133	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.7254291884550644	[3]	[4,4]	9	hSpCas9	positive selection	4303052
70229058	70229081	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.05665778224003837	[3]	[3,2]	1	hSpCas9	positive selection	4303053
70236136	70236159	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.22363102623028994	[3]	[3,1]	-4	hSpCas9	positive selection	4367304
70230775	70230798	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.5928789492070748	[3]	[3,4]	9	hSpCas9	positive selection	4367305
70230816	70230839	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.35057161341604903	[3]	[3,3]	7	hSpCas9	positive selection	4367306
70216223	70216245	2	-	27760321	OCIAML3	viability	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	-0.8754395182980415	[130,77]	[61,19]	-7	hSpCas9	negative selection	4446904
70216892	70216914	2	+	27760321	OCIAML3	viability	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.008844928169967514	[665,636]	[469,569]	0	hSpCas9	negative selection	4446905
70216966	70216988	2	-	27760321	OCIAML3	viability	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	-0.451311385563002	[212,154]	[85,127]	-4	hSpCas9	negative selection	4446906
70224604	70224626	2	-	27760321	OCIAML3	viability	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	1.394741771451133	[275,166]	[317,616]	9	hSpCas9	negative selection	4446907
70230755	70230777	2	-	27760321	OCIAML3	viability	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	1.1194315157021992	[180,166]	[266,332]	9	hSpCas9	negative selection	4446908
70216223	70216245	2	-	27760321	OCIAML2	viability	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	0.43744885847348036	[130,77]	[105,120]	6	hSpCas9	negative selection	4530367
70216892	70216914	2	+	27760321	OCIAML2	viability	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.08104767510779431	[665,636]	[471,671]	1	hSpCas9	negative selection	4530368
70216966	70216988	2	-	27760321	OCIAML2	viability	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	0.8959136151395055	[212,154]	[250,304]	9	hSpCas9	negative selection	4530369
70224604	70224626	2	-	27760321	OCIAML2	viability	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.673322878321946	[275,166]	[229,347]	8	hSpCas9	negative selection	4530370
70230755	70230777	2	-	27760321	OCIAML2	viability	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	0.08899995361519109	[180,166]	[128,176]	1	hSpCas9	negative selection	4530371
70216223	70216245	2	-	27760321	MV411	viability	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	0.7855004449306697	[130,77]	[93,150]	6	hSpCas9	negative selection	4613830
70216892	70216914	2	+	27760321	MV411	viability	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.6307604753805532	[665,636]	[736,560]	4	hSpCas9	negative selection	4613831
70216966	70216988	2	-	27760321	MV411	viability	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	-1.012640085093515	[212,154]	[59,58]	-6	hSpCas9	negative selection	4613832
70224604	70224626	2	-	27760321	MV411	viability	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	-0.47178204309683713	[275,166]	[121,75]	-3	hSpCas9	negative selection	4613833
70230755	70230777	2	-	27760321	MV411	viability	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	0.2177531276609328	[180,166]	[45,264]	1	hSpCas9	negative selection	4613834
70216223	70216245	2	-	27760321	HL60	viability	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	1.009631860470846	[130,77]	[130,208]	9	hSpCas9	negative selection	4697293
70216892	70216914	2	+	27760321	HL60	viability	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.9951887192210406	[665,636]	[859,1276]	9	hSpCas9	negative selection	4697294
70216966	70216988	2	-	27760321	HL60	viability	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	0.8466853136282224	[212,154]	[240,295]	8	hSpCas9	negative selection	4697295
70224604	70224626	2	-	27760321	HL60	viability	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.6613131666095136	[275,166]	[208,357]	7	hSpCas9	negative selection	4697296
70230755	70230777	2	-	27760321	HL60	viability	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	-1.013913829209485	[180,166]	[49,91]	-7	hSpCas9	negative selection	4697297
70216223	70216245	2	-	27760321	HT1080	viability	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	0.6682403545029916	[77,60]	[22,66]	3	hSpCas9	negative selection	4780756
70216892	70216914	2	+	27760321	HT1080	viability	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	1.4803586109991524	[636,496]	[792,451]	7	hSpCas9	negative selection	4780757
70216966	70216988	2	-	27760321	HT1080	viability	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	0.8932241097103826	[154,120]	[135,64]	5	hSpCas9	negative selection	4780758
70224604	70224626	2	-	27760321	HT1080	viability	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.026186216751830083	[166,130]	[6,118]	0	hSpCas9	negative selection	4780759
70230755	70230777	2	-	27760321	HT1080	viability	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	-3.4868556530615487	[166,130]	[0,9]	-7	hSpCas9	negative selection	4780760
70216223	70216245	2	-	27760321	HT29	viability after 7 days	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	0.4174663335283746	[77,60]	[209,46,113]	6	hSpCas9	negative selection	4864219
70216892	70216914	2	+	27760321	HT29	viability after 7 days	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.26059040249366755	[636,496]	[654,907,278]	-4	hSpCas9	negative selection	4864220
70216966	70216988	2	-	27760321	HT29	viability after 7 days	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	0.20244457270992156	[154,120]	[146,219,235]	3	hSpCas9	negative selection	4864221
70224604	70224626	2	-	27760321	HT29	viability after 7 days	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.4108844063491752	[166,130]	[318,322,134]	6	hSpCas9	negative selection	4864222
70230755	70230777	2	-	27760321	HT29	viability after 7 days	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	0.45875642987303045	[166,130]	[236,381,169]	7	hSpCas9	negative selection	4864223
70216223	70216245	2	-	27760321	HT29	viability after 25 days	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	0.024814288909492888	[77,60]	[9,110,130]	0	hSpCas9	negative selection	4947682
70216892	70216914	2	+	27760321	HT29	viability after 25 days	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.36313104248969363	[636,496]	[511,399,608]	-4	hSpCas9	negative selection	4947683
70216966	70216988	2	-	27760321	HT29	viability after 25 days	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	0.9267925025293702	[154,120]	[267,427,193]	9	hSpCas9	negative selection	4947684
70224604	70224626	2	-	27760321	HT29	viability after 25 days	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	1.4366014837471721	[166,130]	[389,595,393]	9	hSpCas9	negative selection	4947685
70230755	70230777	2	-	27760321	HT29	viability after 25 days	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	1.120580833781646	[166,130]	[338,329,451]	9	hSpCas9	negative selection	4947686
70216223	70216245	2	-	27760321	HT29	viability after 22 days	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	0.7678031589897563	[77,60]	[2,176,234]	8	hSpCas9	negative selection	5031145
70216892	70216914	2	+	27760321	HT29	viability after 22 days	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.28038576003642746	[636,496]	[1041,705,631]	3	hSpCas9	negative selection	5031146
70216966	70216988	2	-	27760321	HT29	viability after 22 days	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	0.9328422306855986	[154,120]	[239,309,365]	9	hSpCas9	negative selection	5031147
70224604	70224626	2	-	27760321	HT29	viability after 22 days	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	1.450773727473891	[166,130]	[399,325,690]	9	hSpCas9	negative selection	5031148
70230755	70230777	2	-	27760321	HT29	viability after 22 days	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	1.035625488627392	[166,130]	[516,209,327]	9	hSpCas9	negative selection	5031149
70216223	70216245	2	-	27760321	HT29	viability after 19 days	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	-0.15010306656866668	[77,60]	[60,33,116]	-1	hSpCas9	negative selection	5114608
70216892	70216914	2	+	27760321	HT29	viability after 19 days	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.04626424803550522	[636,496]	[625,700,558]	0	hSpCas9	negative selection	5114609
70216966	70216988	2	-	27760321	HT29	viability after 19 days	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	-0.04285638278068249	[154,120]	[134,125,194]	0	hSpCas9	negative selection	5114610
70224604	70224626	2	-	27760321	HT29	viability after 19 days	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	1.1217946447703482	[166,130]	[571,199,361]	9	hSpCas9	negative selection	5114611
70230755	70230777	2	-	27760321	HT29	viability after 19 days	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	0.8390412584830366	[166,130]	[220,143,531]	8	hSpCas9	negative selection	5114612
70216223	70216245	2	-	27760321	HT29	viability after 16 days	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	0.3559873927970134	[77,60]	[23,192,71]	4	hSpCas9	negative selection	5198071
70216892	70216914	2	+	27760321	HT29	viability after 16 days	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.30220684816311655	[636,496]	[671,406,481]	-3	hSpCas9	negative selection	5198072
70216966	70216988	2	-	27760321	HT29	viability after 16 days	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	0.9452154845248169	[154,120]	[211,402,265]	9	hSpCas9	negative selection	5198073
70224604	70224626	2	-	27760321	HT29	viability after 16 days	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	1.364784909390833	[166,130]	[560,303,438]	9	hSpCas9	negative selection	5198074
70230755	70230777	2	-	27760321	HT29	viability after 16 days	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	0.26090100119179116	[166,130]	[239,53,312]	3	hSpCas9	negative selection	5198075
70216223	70216245	2	-	27760321	HT29	viability after 13 days	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	0.28690158348063166	[77,60]	[54,103,133]	3	hSpCas9	negative selection	5281534
70216892	70216914	2	+	27760321	HT29	viability after 13 days	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.2819411482532005	[636,496]	[573,612,441]	-3	hSpCas9	negative selection	5281535
70216966	70216988	2	-	27760321	HT29	viability after 13 days	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	0.4262714057367676	[154,120]	[288,137,217]	5	hSpCas9	negative selection	5281536
70224604	70224626	2	-	27760321	HT29	viability after 13 days	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.928309415467725	[166,130]	[344,362,281]	9	hSpCas9	negative selection	5281537
70230755	70230777	2	-	27760321	HT29	viability after 13 days	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	0.38471920729828446	[166,130]	[183,159,326]	5	hSpCas9	negative selection	5281538
70216223	70216245	2	-	27760321	HT29	viability after 10 days	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	0.31417444868747735	[77,60]	[123,86,111]	4	hSpCas9	negative selection	5364997
70216892	70216914	2	+	27760321	HT29	viability after 10 days	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.2605467911717692	[636,496]	[762,518,490]	-3	hSpCas9	negative selection	5364998
70216966	70216988	2	-	27760321	HT29	viability after 10 days	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	0.44683487879301464	[154,120]	[364,185,153]	6	hSpCas9	negative selection	5364999
70224604	70224626	2	-	27760321	HT29	viability after 10 days	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.6841369339182056	[166,130]	[230,229,430]	8	hSpCas9	negative selection	5365000
70230755	70230777	2	-	27760321	HT29	viability after 10 days	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	0.5030689144208439	[166,130]	[279,172,333]	7	hSpCas9	negative selection	5365001
70216223	70216245	2	-	27760321	MOLM13	viability	TTCGAGTCTTTCCAGATAAAGG	TIA1	ENSG00000116001	2.0137513701676757	[130,77]	[39,398]	9	hSpCas9	negative selection	5448460
70216892	70216914	2	+	27760321	MOLM13	viability	ATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	1.6282677422317877	[665,636]	[1218,1068]	9	hSpCas9	negative selection	5448461
70216966	70216988	2	-	27760321	MOLM13	viability	AAAACGCCATTCAACAGATGGG	TIA1	ENSG00000116001	0.054572586052555216	[212,154]	[129,86]	0	hSpCas9	negative selection	5448462
70224604	70224626	2	-	27760321	MOLM13	viability	GCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.06006453167455594	[275,166]	[200,65]	0	hSpCas9	negative selection	5448463
70230755	70230777	2	-	27760321	MOLM13	viability	GGACGGAAGATAATGGGTAAGG	TIA1	ENSG00000116001	-0.5964638459020437	[180,166]	[112,23]	-4	hSpCas9	negative selection	5448464
70248605	70248628	2	+	27661255	K562	viability	GAAACCCCAATACAAGATGGCGG	TIA1	ENSG00000116001	-0.1833569386126257	[637,659]	[499,418]	-5	dCas9-KRAB	negative selection	5517261
70248538	70248561	2	-	27661255	K562	viability	GGAGGAGGCGGAGTAACCTCTGG	TIA1	ENSG00000116001	0.03215446273679268	[1705,1742]	[1596,1246]	1	dCas9-KRAB	negative selection	5517262
70248553	70248576	2	-	27661255	K562	viability	GTAATTGCCGCCGGAGGAGGAGG	TIA1	ENSG00000116001	-1.0764752959021522	[1170,1131]	[504,377]	-8	dCas9-KRAB	negative selection	5517263
70248611	70248634	2	-	27661255	K562	viability	GGCTCGCCGCCATCTTGTATTGG	TIA1	ENSG00000116001	-0.0814647916357899	[411,455]	[366,292]	-3	dCas9-KRAB	negative selection	5517264
70229063	70229086	2	+	27260156	BXPC3	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.14119142810378082	[260]	[269,200,226,295]	-3	hSpCas9	negative selection	5575511
70236110	70236133	2	-	27260156	BXPC3	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.6532546189570723	[471]	[699,686,745,1007]	9	hSpCas9	negative selection	5575512
70229058	70229081	2	-	27260156	BXPC3	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.18672990040100934	[717]	[782,845,884,913]	4	hSpCas9	negative selection	5575513
70236136	70236159	2	+	27260156	BXPC3	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	0.13987207802359825	[818]	[693,639,1576,908]	3	hSpCas9	negative selection	5639764
70230775	70230798	2	-	27260156	BXPC3	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.2520545395238644	[586]	[701,671,720,843]	5	hSpCas9	negative selection	5639765
70230816	70230839	2	+	27260156	BXPC3	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.04647187797942062	[557]	[591,498,603,561]	-1	hSpCas9	negative selection	5639766
70229063	70229086	2	+	27260156	A673	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.13591904745722128	[260]	[324,342,337,369]	3	hSpCas9	negative selection	5696762
70236110	70236133	2	-	27260156	A673	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.5285779420448883	[471]	[822,788,878,775]	9	hSpCas9	negative selection	5696763
70229058	70229081	2	-	27260156	A673	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.22016672083923483	[717]	[957,937,970,1152]	5	hSpCas9	negative selection	5696764
70236136	70236159	2	+	27260156	A673	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.39624277055124385	[818]	[856,666,749,726]	-7	hSpCas9	negative selection	5761015
70230775	70230798	2	-	27260156	A673	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.13298053150831068	[586]	[770,770,771,775]	3	hSpCas9	negative selection	5761016
70230816	70230839	2	+	27260156	A673	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.19477509196441217	[557]	[689,434,584,649]	-5	hSpCas9	negative selection	5761017
70229063	70229086	2	+	27260156	A375	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.13592044269835313	[260]	[266,442,325,318]	2	hSpCas9	negative selection	5818013
70236110	70236133	2	-	27260156	A375	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.9193602912990774	[471]	[1248,1148,1011,801]	9	hSpCas9	negative selection	5818014
70229058	70229081	2	-	27260156	A375	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.00573898494198255	[717]	[821,957,882,730]	0	hSpCas9	negative selection	5818015
70236136	70236159	2	+	27260156	A375	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	0.09913467981303048	[818]	[681,1313,1284,869]	1	hSpCas9	negative selection	5882266
70230775	70230798	2	-	27260156	A375	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.33964506496159724	[586]	[844,1238,700,747]	5	hSpCas9	negative selection	5882267
70230816	70230839	2	+	27260156	A375	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.08425790211006987	[557]	[600,1017,524,664]	1	hSpCas9	negative selection	5882268
70229063	70229086	2	+	27260156	COLO741	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.06083070939251278	[260]	[272,393,367]	1	hSpCas9	negative selection	5939264
70236110	70236133	2	-	27260156	COLO741	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.3249900003159806	[471]	[898,781,606]	6	hSpCas9	negative selection	5939265
70229058	70229081	2	-	27260156	COLO741	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.13936778671790462	[717]	[1347,921,802]	3	hSpCas9	negative selection	5939266
70236136	70236159	2	+	27260156	COLO741	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.09116828740090144	[818]	[1082,1107,777]	-2	hSpCas9	negative selection	6003517
70230775	70230798	2	-	27260156	COLO741	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	-0.09450873911152677	[586]	[754,608,742]	-2	hSpCas9	negative selection	6003518
70230816	70230839	2	+	27260156	COLO741	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.10609309038634776	[557]	[631,601,742]	-2	hSpCas9	negative selection	6003519
70229063	70229086	2	+	27260156	CAL120	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.0030408685158475057	[260]	[499,194,303]	0	hSpCas9	negative selection	6060515
70236110	70236133	2	-	27260156	CAL120	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	1.1279357242989259	[471]	[2079,987,908]	9	hSpCas9	negative selection	6060516
70229058	70229081	2	-	27260156	CAL120	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.245672445091496	[717]	[1486,755,999]	3	hSpCas9	negative selection	6060517
70236136	70236159	2	+	27260156	CAL120	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.12224695038436462	[818]	[891,917,990]	-2	hSpCas9	negative selection	6124768
70230775	70230798	2	-	27260156	CAL120	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	-0.052046163723654004	[586]	[905,603,634]	0	hSpCas9	negative selection	6124769
70230816	70230839	2	+	27260156	CAL120	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.02460982497032932	[557]	[1037,544,520]	0	hSpCas9	negative selection	6124770
70229063	70229086	2	+	27260156	CADOES1	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.27933697851497974	[260]	[314,241,332,287]	5	hSpCas9	negative selection	6181766
70236110	70236133	2	-	27260156	CADOES1	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.930675351591815	[471]	[1078,665,768,831]	9	hSpCas9	negative selection	6181767
70229058	70229081	2	-	27260156	CADOES1	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.2778138325449142	[717]	[815,768,849,802]	5	hSpCas9	negative selection	6181768
70236136	70236159	2	+	27260156	CADOES1	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.04259728343666924	[818]	[584,733,888,750]	0	hSpCas9	negative selection	6246019
70230775	70230798	2	-	27260156	CADOES1	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.22578010645770724	[586]	[487,781,528,759]	4	hSpCas9	negative selection	6246020
70230816	70230839	2	+	27260156	CADOES1	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.10921703825100057	[557]	[426,580,483,430]	-2	hSpCas9	negative selection	6246021
70229063	70229086	2	+	27260156	EWS502	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.26986727204901706	[260]	[417,358,286,249]	5	hSpCas9	negative selection	6303017
70236110	70236133	2	-	27260156	EWS502	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.6641384202816826	[471]	[771,751,977,660]	9	hSpCas9	negative selection	6303018
70229058	70229081	2	-	27260156	EWS502	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.16087757148786286	[717]	[659,808,1119,835]	3	hSpCas9	negative selection	6303019
70236136	70236159	2	+	27260156	EWS502	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.31664486163387773	[818]	[461,586,763,1027]	-5	hSpCas9	negative selection	6367270
70230775	70230798	2	-	27260156	EWS502	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.46843336455640033	[586]	[873,989,952,595]	7	hSpCas9	negative selection	6367271
70230816	70230839	2	+	27260156	EWS502	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.04044299837690993	[557]	[379,517,681,756]	0	hSpCas9	negative selection	6367272
70229063	70229086	2	+	27260156	EW8	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.3353849497662629	[260]	[306,279,262,221]	6	hSpCas9	negative selection	6424268
70236110	70236133	2	-	27260156	EW8	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.6277676442543706	[471]	[766,630,438,570]	9	hSpCas9	negative selection	6424269
70229058	70229081	2	-	27260156	EW8	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	-0.03297825629191731	[717]	[532,826,389,550]	0	hSpCas9	negative selection	6424270
70236136	70236159	2	+	27260156	EW8	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.41183837384279054	[818]	[545,504,435,522]	-6	hSpCas9	negative selection	6488521
70230775	70230798	2	-	27260156	EW8	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.350924748066987	[586]	[595,628,564,640]	6	hSpCas9	negative selection	6488522
70230816	70230839	2	+	27260156	EW8	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.00635742990680957	[557]	[428,471,392,528]	0	hSpCas9	negative selection	6488523
70229063	70229086	2	+	27260156	CORL105	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.09468804418786825	[260]	[178,323,343,301]	-2	hSpCas9	negative selection	6545519
70236110	70236133	2	-	27260156	CORL105	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.7075407919435942	[471]	[903,949,999,769]	9	hSpCas9	negative selection	6545520
70229058	70229081	2	-	27260156	CORL105	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.2029415516048969	[717]	[1138,951,907,867]	4	hSpCas9	negative selection	6545521
70236136	70236159	2	+	27260156	CORL105	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.29848966786265896	[818]	[856,759,820,689]	-5	hSpCas9	negative selection	6609772
70230775	70230798	2	-	27260156	CORL105	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.3723119398629701	[586]	[746,634,1106,1101]	7	hSpCas9	negative selection	6609773
70230816	70230839	2	+	27260156	CORL105	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.09467811339773599	[557]	[853,471,975,541]	1	hSpCas9	negative selection	6609774
70229063	70229086	2	+	27260156	HS294T	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.3185096006200274	[260]	[67,105,72,75]	-4	hSpCas9	negative selection	6666770
70236110	70236133	2	-	27260156	HS294T	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.6287079087690745	[471]	[259,307,253,311]	7	hSpCas9	negative selection	6666771
70229058	70229081	2	-	27260156	HS294T	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.18571171358590188	[717]	[274,309,365,314]	2	hSpCas9	negative selection	6666772
70236136	70236159	2	+	27260156	HS294T	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	0.022725396860131863	[818]	[242,333,418,291]	0	hSpCas9	negative selection	6731023
70230775	70230798	2	-	27260156	HS294T	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.46731412041238146	[586]	[268,298,336,361]	6	hSpCas9	negative selection	6731024
70230816	70230839	2	+	27260156	HS294T	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.02687477783243944	[557]	[149,156,172,444]	0	hSpCas9	negative selection	6731025
70229063	70229086	2	+	27260156	HCC44	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.11385104223001563	[260]	[392,284,315,292]	1	hSpCas9	negative selection	6788021
70236110	70236133	2	-	27260156	HCC44	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.6593371611543378	[471]	[937,630,1376,559]	9	hSpCas9	negative selection	6788022
70229058	70229081	2	-	27260156	HCC44	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.23622056169821226	[717]	[934,622,1226,1119]	4	hSpCas9	negative selection	6788023
70236136	70236159	2	+	27260156	HCC44	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.07028424694932345	[818]	[933,826,1092,721]	-1	hSpCas9	negative selection	6852274
70230775	70230798	2	-	27260156	HCC44	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.16562210790921894	[586]	[716,557,1240,571]	2	hSpCas9	negative selection	6852275
70230816	70230839	2	+	27260156	HCC44	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.05655908534008289	[557]	[929,565,662,504]	0	hSpCas9	negative selection	6852276
70229063	70229086	2	+	27260156	G402	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.26524406703725356	[260]	[415,290,502,321]	3	hSpCas9	negative selection	6909272
70236110	70236133	2	-	27260156	G402	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	1.008425025749373	[471]	[1542,804,1371,954]	9	hSpCas9	negative selection	6909273
70229058	70229081	2	-	27260156	G402	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	-0.06016877983767965	[717]	[980,718,1121,562]	0	hSpCas9	negative selection	6909274
70236136	70236159	2	+	27260156	G402	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	0.11819473340284636	[818]	[1370,660,1124,1188]	1	hSpCas9	negative selection	6973525
70230775	70230798	2	-	27260156	G402	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.4759917193317547	[586]	[1452,1226,629,761]	6	hSpCas9	negative selection	6973526
70230816	70230839	2	+	27260156	G402	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.0959607412461286	[557]	[668,526,647,696]	-1	hSpCas9	negative selection	6973527
70229063	70229086	2	+	27260156	L33	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.5287578447576342	[260]	[161,80,106,193]	-8	hSpCas9	negative selection	7030523
70236110	70236133	2	-	27260156	L33	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.5089484078595214	[471]	[597,322,444,594]	8	hSpCas9	negative selection	7030524
70229058	70229081	2	-	27260156	L33	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.5581359750509765	[717]	[1145,445,627,992]	9	hSpCas9	negative selection	7030525
70236136	70236159	2	+	27260156	L33	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.5176142275016984	[818]	[624,257,339,491]	-8	hSpCas9	negative selection	7094776
70230775	70230798	2	-	27260156	L33	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.0003631618538686987	[586]	[456,260,454,534]	0	hSpCas9	negative selection	7094777
70230816	70230839	2	+	27260156	L33	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.3923101994460464	[557]	[472,151,332,326]	-7	hSpCas9	negative selection	7094778
70229063	70229086	2	+	27260156	K562	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.48470656149403823	[260]	[236,133,198,102]	-5	hSpCas9	negative selection	7151774
70236110	70236133	2	-	27260156	K562	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.5187493152394326	[471]	[865,441,697,425]	6	hSpCas9	negative selection	7151775
70229058	70229081	2	-	27260156	K562	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.5321026324600533	[717]	[778,958,1107,835]	6	hSpCas9	negative selection	7151776
70236136	70236159	2	+	27260156	K562	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.03225916198102763	[818]	[970,488,833,571]	0	hSpCas9	negative selection	7216027
70230775	70230798	2	-	27260156	K562	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.5592176545433294	[586]	[809,925,1001,385]	7	hSpCas9	negative selection	7216028
70230816	70230839	2	+	27260156	K562	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.23053838287236808	[557]	[770,635,399,537]	3	hSpCas9	negative selection	7216029
70229063	70229086	2	+	27260156	HT29	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.07634277473319628	[260]	[369,394,310,274]	1	hSpCas9	negative selection	7273025
70236110	70236133	2	-	27260156	HT29	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.6031519522518246	[471]	[982,864,1082,591]	9	hSpCas9	negative selection	7273026
70229058	70229081	2	-	27260156	HT29	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.28931617622924977	[717]	[1093,1106,1334,765]	5	hSpCas9	negative selection	7273027
70236136	70236159	2	+	27260156	HT29	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.16152550885785188	[818]	[824,990,988,767]	-3	hSpCas9	negative selection	7337278
70230775	70230798	2	-	27260156	HT29	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.023723162245815943	[586]	[939,819,615,564]	0	hSpCas9	negative selection	7337279
70230816	70230839	2	+	27260156	HT29	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.026421864960591457	[557]	[769,591,849,472]	0	hSpCas9	negative selection	7337280
70229063	70229086	2	+	27260156	MHHES1	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.10462022307505914	[260]	[251,405,224,225]	-2	hSpCas9	negative selection	7394276
70236110	70236133	2	-	27260156	MHHES1	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.6470785732843437	[471]	[1172,944,782,532]	9	hSpCas9	negative selection	7394277
70229058	70229081	2	-	27260156	MHHES1	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.17335742777486285	[717]	[1284,1079,781,611]	3	hSpCas9	negative selection	7394278
70236136	70236159	2	+	27260156	MHHES1	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.17089794393265545	[818]	[672,881,1012,706]	-3	hSpCas9	negative selection	7458529
70230775	70230798	2	-	27260156	MHHES1	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.34932709169817516	[586]	[662,809,1093,774]	6	hSpCas9	negative selection	7458530
70230816	70230839	2	+	27260156	MHHES1	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.27489108126544637	[557]	[603,428,485,541]	-5	hSpCas9	negative selection	7458531
70229063	70229086	2	+	27260156	MEWO	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.37163320710685266	[260]	[310,154,123]	-7	hSpCas9	negative selection	7515527
70236110	70236133	2	-	27260156	MEWO	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.5159600823555187	[471]	[839,547,546]	9	hSpCas9	negative selection	7515528
70229058	70229081	2	-	27260156	MEWO	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.19324970089324223	[717]	[1013,672,664]	4	hSpCas9	negative selection	7515529
70236136	70236159	2	+	27260156	MEWO	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.5145523846718824	[818]	[729,431,484]	-8	hSpCas9	negative selection	7579780
70230775	70230798	2	-	27260156	MEWO	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.19825227160100317	[586]	[858,512,562]	4	hSpCas9	negative selection	7579781
70230816	70230839	2	+	27260156	MEWO	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.1969137656971054	[557]	[644,442,314]	-4	hSpCas9	negative selection	7579782
70229063	70229086	2	+	27260156	LNCAPCLONEFGC	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.06973551418787949	[260]	[314,197,231,246]	1	hSpCas9	negative selection	7636778
70236110	70236133	2	-	27260156	LNCAPCLONEFGC	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.708851284983229	[471]	[537,573,790,916]	9	hSpCas9	negative selection	7636779
70229058	70229081	2	-	27260156	LNCAPCLONEFGC	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.3760511314743753	[717]	[974,601,1037,802]	6	hSpCas9	negative selection	7636780
70236136	70236159	2	+	27260156	LNCAPCLONEFGC	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.18688206055974443	[818]	[854,450,739,582]	-3	hSpCas9	negative selection	7701031
70230775	70230798	2	-	27260156	LNCAPCLONEFGC	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.1534066772554889	[586]	[626,578,676,494]	2	hSpCas9	negative selection	7701032
70230816	70230839	2	+	27260156	LNCAPCLONEFGC	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.05644754182888054	[557]	[512,629,575,383]	0	hSpCas9	negative selection	7701033
70229063	70229086	2	+	27260156	PANC0327	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.10875848251662834	[260]	[218,292,311,167]	1	hSpCas9	negative selection	7758029
70236110	70236133	2	-	27260156	PANC0327	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.2836920419116338	[471]	[668,306,667,436]	4	hSpCas9	negative selection	7758030
70229058	70229081	2	-	27260156	PANC0327	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.022331638256249176	[717]	[810,586,602,610]	0	hSpCas9	negative selection	7758031
70236136	70236159	2	+	27260156	PANC0327	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.025889245095554902	[818]	[526,901,893,495]	0	hSpCas9	negative selection	7822282
70230775	70230798	2	-	27260156	PANC0327	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.2596456433039909	[586]	[503,523,721,749]	4	hSpCas9	negative selection	7822283
70230816	70230839	2	+	27260156	PANC0327	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.32682243362329244	[557]	[721,415,917,465]	5	hSpCas9	negative selection	7822284
70229063	70229086	2	+	27260156	NCIH2009	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.5481764042470398	[260]	[327,208,226]	-6	hSpCas9	negative selection	7879280
70236110	70236133	2	-	27260156	NCIH2009	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.6280863822760901	[471]	[1244,1046,807]	8	hSpCas9	negative selection	7879281
70229058	70229081	2	-	27260156	NCIH2009	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.3974264243318104	[717]	[1459,1437,1088]	5	hSpCas9	negative selection	7879282
70236136	70236159	2	+	27260156	NCIH2009	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.42579001897721347	[818]	[891,795,874]	-5	hSpCas9	negative selection	7943533
70230775	70230798	2	-	27260156	NCIH2009	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.2541408094906156	[586]	[1260,899,828]	3	hSpCas9	negative selection	7943534
70230816	70230839	2	+	27260156	NCIH2009	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.10900473564110363	[557]	[866,606,723]	-1	hSpCas9	negative selection	7943535
70229063	70229086	2	+	27260156	NCIH1373	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.2737894051990215	[260]	[286,305,205,42]	-3	hSpCas9	negative selection	8000531
70236110	70236133	2	-	27260156	NCIH1373	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	1.1201408419431922	[471]	[1272,695,1472,319]	9	hSpCas9	negative selection	8000532
70229058	70229081	2	-	27260156	NCIH1373	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	-0.14161398981650752	[717]	[629,1000,630,157]	-1	hSpCas9	negative selection	8000533
70236136	70236159	2	+	27260156	NCIH1373	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	0.59673074992875	[818]	[1179,1718,1066,400]	6	hSpCas9	negative selection	8064784
70230775	70230798	2	-	27260156	NCIH1373	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.7281136913963548	[586]	[1246,648,625,516]	7	hSpCas9	negative selection	8064785
70230816	70230839	2	+	27260156	NCIH1373	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.5586190099831595	[557]	[1288,628,656,319]	5	hSpCas9	negative selection	8064786
70229063	70229086	2	+	27260156	PATU8902	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.33721231894949	[260]	[315,673,45,967]	3	hSpCas9	negative selection	8121782
70236110	70236133	2	-	27260156	PATU8902	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	1.2350494242845838	[471]	[1779,1991,1090,1414]	9	hSpCas9	negative selection	8121783
70229058	70229081	2	-	27260156	PATU8902	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	-0.10809343625764112	[717]	[1042,650,989,1010]	-1	hSpCas9	negative selection	8121784
70236136	70236159	2	+	27260156	PATU8902	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.49970181573714073	[818]	[1063,951,519,748]	-5	hSpCas9	negative selection	8186035
70230775	70230798	2	-	27260156	PATU8902	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.8467484036271611	[586]	[1774,1948,1036,1183]	8	hSpCas9	negative selection	8186036
70230816	70230839	2	+	27260156	PATU8902	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.2871690293076866	[557]	[873,664,323,773]	-3	hSpCas9	negative selection	8186037
70229063	70229086	2	+	27260156	PANC1	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.11489917894132695	[260]	[291,301,211,181]	1	hSpCas9	negative selection	8243033
70236110	70236133	2	-	27260156	PANC1	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.6125246357583591	[471]	[605,718,504,652]	8	hSpCas9	negative selection	8243034
70229058	70229081	2	-	27260156	PANC1	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.18815000377415525	[717]	[798,637,770,593]	3	hSpCas9	negative selection	8243035
70236136	70236159	2	+	27260156	PANC1	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.2890841191303104	[818]	[629,718,547,445]	-4	hSpCas9	negative selection	8307286
70230775	70230798	2	-	27260156	PANC1	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.1877246127843168	[586]	[560,786,599,410]	3	hSpCas9	negative selection	8307287
70230816	70230839	2	+	27260156	PANC1	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.0052821411075319735	[557]	[519,588,595,268]	0	hSpCas9	negative selection	8307288
70229063	70229086	2	+	27260156	PANC0813	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.19173378172541589	[260]	[302,228,521,342]	3	hSpCas9	negative selection	8364284
70236110	70236133	2	-	27260156	PANC0813	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	1.2638205761008572	[471]	[1186,1471,1529,1132]	9	hSpCas9	negative selection	8364285
70229058	70229081	2	-	27260156	PANC0813	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.3364435054580922	[717]	[1106,991,1287,885]	5	hSpCas9	negative selection	8364286
70236136	70236159	2	+	27260156	PANC0813	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.2385089357726241	[818]	[807,855,839,758]	-4	hSpCas9	negative selection	8428537
70230775	70230798	2	-	27260156	PANC0813	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.29805612986715174	[586]	[1003,1027,653,723]	5	hSpCas9	negative selection	8428538
70230816	70230839	2	+	27260156	PANC0813	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.19645251783431084	[557]	[522,505,559,686]	-3	hSpCas9	negative selection	8428539
70229063	70229086	2	+	27260156	RDES	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.1872004852182354	[260]	[222,258,472,459]	3	hSpCas9	negative selection	8485535
70236110	70236133	2	-	27260156	RDES	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.7821200237137229	[471]	[827,864,1033,1023]	9	hSpCas9	negative selection	8485536
70229058	70229081	2	-	27260156	RDES	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.04422030801125665	[717]	[768,840,768,1043]	0	hSpCas9	negative selection	8485537
70236136	70236159	2	+	27260156	RDES	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.09392368559297026	[818]	[867,822,971,842]	-1	hSpCas9	negative selection	8549788
70230775	70230798	2	-	27260156	RDES	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.2841452382154421	[586]	[499,799,842,1263]	4	hSpCas9	negative selection	8549789
70230816	70230839	2	+	27260156	RDES	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.29958372220467744	[557]	[640,711,987,850]	5	hSpCas9	negative selection	8549790
70229063	70229086	2	+	27260156	PC3	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.09713752307257473	[260]	[107,179,576,285]	-2	hSpCas9	negative selection	8606786
70236110	70236133	2	-	27260156	PC3	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.5441816880808896	[471]	[419,647,1133,773]	9	hSpCas9	negative selection	8606787
70229058	70229081	2	-	27260156	PC3	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.24209723617339218	[717]	[598,845,1459,730]	5	hSpCas9	negative selection	8606788
70236136	70236159	2	+	27260156	PC3	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.14610819880924286	[818]	[361,767,1264,871]	-3	hSpCas9	negative selection	8671039
70230775	70230798	2	-	27260156	PC3	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.22901401113880687	[586]	[456,557,935,937]	5	hSpCas9	negative selection	8671040
70230816	70230839	2	+	27260156	PC3	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.0847553442901604	[557]	[368,453,801,599]	-2	hSpCas9	negative selection	8671041
70229063	70229086	2	+	27260156	PATU8988T	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.04135629614949354	[260]	[153,134,449,286]	0	hSpCas9	negative selection	8728037
70236110	70236133	2	-	27260156	PATU8988T	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.45866109567907876	[471]	[594,634,635,642]	7	hSpCas9	negative selection	8728038
70229058	70229081	2	-	27260156	PATU8988T	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.3897256446109416	[717]	[902,969,1105,637]	6	hSpCas9	negative selection	8728039
70236136	70236159	2	+	27260156	PATU8988T	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.1729940351884358	[818]	[726,630,843,587]	-3	hSpCas9	negative selection	8792290
70230775	70230798	2	-	27260156	PATU8988T	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.4376971009980885	[586]	[783,1071,542,699]	7	hSpCas9	negative selection	8792291
70230816	70230839	2	+	27260156	PATU8988T	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.007212424970566039	[557]	[610,578,365,623]	0	hSpCas9	negative selection	8792292
70229063	70229086	2	+	27260156	T47D	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.06527274997113508	[260]	[384,271,260,360]	1	hSpCas9	negative selection	8849288
70236110	70236133	2	-	27260156	T47D	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.5311141048198447	[471]	[818,738,859,762]	9	hSpCas9	negative selection	8849289
70229058	70229081	2	-	27260156	T47D	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.23364484218661075	[717]	[884,996,878,1178]	5	hSpCas9	negative selection	8849290
70236136	70236159	2	+	27260156	T47D	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.14445992320535495	[818]	[891,871,936,745]	-3	hSpCas9	negative selection	8913541
70230775	70230798	2	-	27260156	T47D	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.13762494317775614	[586]	[832,702,643,837]	3	hSpCas9	negative selection	8913542
70230816	70230839	2	+	27260156	T47D	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.07794568520039794	[557]	[649,569,573,675]	-2	hSpCas9	negative selection	8913543
70229063	70229086	2	+	27260156	SU8686	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.4452295668699138	[260]	[138,188,256,179]	-6	hSpCas9	negative selection	8970539
70236110	70236133	2	-	27260156	SU8686	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.7306302888763753	[471]	[726,736,746,922]	9	hSpCas9	negative selection	8970540
70229058	70229081	2	-	27260156	SU8686	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.1605700281980854	[717]	[564,752,911,1017]	2	hSpCas9	negative selection	8970541
70236136	70236159	2	+	27260156	SU8686	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.1951222923703001	[818]	[550,732,688,904]	-3	hSpCas9	negative selection	9034792
70230775	70230798	2	-	27260156	SU8686	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.19597461661187882	[586]	[671,604,724,668]	3	hSpCas9	negative selection	9034793
70230816	70230839	2	+	27260156	SU8686	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.002320993760923179	[557]	[581,453,505,702]	0	hSpCas9	negative selection	9034794
70229063	70229086	2	+	27260156	SKES1	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.032987246934632286	[260]	[273,258,295,236]	0	hSpCas9	negative selection	9091790
70236110	70236133	2	-	27260156	SKES1	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.5265506469761493	[471]	[818,760,657,516]	9	hSpCas9	negative selection	9091791
70229058	70229081	2	-	27260156	SKES1	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.3364744277088312	[717]	[814,1073,803,921]	7	hSpCas9	negative selection	9091792
70236136	70236159	2	+	27260156	SKES1	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.36446394639852586	[818]	[729,621,709,496]	-7	hSpCas9	negative selection	9156043
70230775	70230798	2	-	27260156	SKES1	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.14477760247123672	[586]	[828,543,593,630]	3	hSpCas9	negative selection	9156044
70230816	70230839	2	+	27260156	SKES1	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	0.10850074928051337	[557]	[902,683,391,483]	2	hSpCas9	negative selection	9156045
70229063	70229086	2	+	27260156	TOV112D	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.3828251469801478	[260]	[253,141,205,189]	-6	hSpCas9	negative selection	9213041
70236110	70236133	2	-	27260156	TOV112D	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.5728948163568203	[471]	[716,926,598,626]	8	hSpCas9	negative selection	9213042
70229058	70229081	2	-	27260156	TOV112D	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.2927455685859207	[717]	[974,991,840,752]	5	hSpCas9	negative selection	9213043
70236136	70236159	2	+	27260156	TOV112D	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.41961128779351753	[818]	[582,896,596,446]	-7	hSpCas9	negative selection	9277294
70230775	70230798	2	-	27260156	TOV112D	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	-0.029309905226889088	[586]	[704,428,529,612]	0	hSpCas9	negative selection	9277295
70230816	70230839	2	+	27260156	TOV112D	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.13475817151106267	[557]	[586,658,441,393]	-3	hSpCas9	negative selection	9277296
70229063	70229086	2	+	27260156	TC71	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.12386101622781209	[260]	[183,212,359,268]	-3	hSpCas9	negative selection	9334292
70236110	70236133	2	-	27260156	TC71	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.5338715313689506	[471]	[716,793,646,777]	9	hSpCas9	negative selection	9334293
70229058	70229081	2	-	27260156	TC71	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.27688254227203535	[717]	[791,1003,929,1011]	6	hSpCas9	negative selection	9334294
70236136	70236159	2	+	27260156	TC71	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.1285733024012875	[818]	[808,761,716,934]	-3	hSpCas9	negative selection	9398545
70230775	70230798	2	-	27260156	TC71	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.16167530005678515	[586]	[701,739,694,676]	4	hSpCas9	negative selection	9398546
70230816	70230839	2	+	27260156	TC71	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.06165001851342419	[557]	[650,442,592,604]	-1	hSpCas9	negative selection	9398547
70229063	70229086	2	+	27260156	TC32	viability	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.04949473577771768	[260]	[196,184,423,257]	0	hSpCas9	negative selection	9455543
70236110	70236133	2	-	27260156	TC32	viability	CTGCAACTCTTTAGCCAGATTGG	TIA1	ENSG00000116001	0.5774640732691155	[471]	[767,336,903,757]	8	hSpCas9	negative selection	9455544
70229058	70229081	2	-	27260156	TC32	viability	GTCAGCACACAGCGTTCACAAGG	TIA1	ENSG00000116001	0.1990674671853362	[717]	[787,557,998,828]	3	hSpCas9	negative selection	9455545
70236136	70236159	2	+	27260156	TC32	viability	TAGAGCTTCTGTCACATCTCTGG	TIA1	ENSG00000116001	-0.13877012257201682	[818]	[801,338,1021,777]	-2	hSpCas9	negative selection	9519796
70230775	70230798	2	-	27260156	TC32	viability	GCAGCATTAGCTGCTATGAATGG	TIA1	ENSG00000116001	0.4951457370212032	[586]	[549,786,948,832]	8	hSpCas9	negative selection	9519797
70230816	70230839	2	+	27260156	TC32	viability	ATGAAACTCCACAAAACAATAGG	TIA1	ENSG00000116001	-0.015540627773094284	[557]	[443,435,709,527]	0	hSpCas9	negative selection	9519798
70214371	70214394	2	-	27869803	HPAFII	viability after 27 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	0.13894750593886623	[173]	[169,42,NaN]	1	hSpCas9	negative selection	9575555
70215360	70215383	2	+	27869803	HPAFII	viability after 27 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-0.9642446026742068	[222]	[70,50,NaN]	-6	hSpCas9	negative selection	9575556
70216891	70216914	2	+	27869803	HPAFII	viability after 27 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.6275814633630763	[91]	[89,61,NaN]	5	hSpCas9	negative selection	9575557
70224616	70224639	2	-	27869803	HPAFII	viability after 27 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	-0.6214546251515396	[273]	[67,114,NaN]	-4	hSpCas9	negative selection	9575558
70225343	70225366	2	+	27869803	HPAFII	viability after 27 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	1.029965304413487	[465]	[400,582,NaN]	8	hSpCas9	negative selection	9575559
70229063	70229086	2	+	27869803	HPAFII	viability after 27 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.7101186595838901	[446]	[444,333,NaN]	6	hSpCas9	negative selection	9575560
70214371	70214394	2	-	27869803	HPAFII	viability after 15 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	-0.16425174878127224	[173]	[304,80,NaN]	-2	hSpCas9	negative selection	9658004
70215360	70215383	2	+	27869803	HPAFII	viability after 15 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.08257564983582809	[222]	[246,257,NaN]	1	hSpCas9	negative selection	9658005
70216891	70216914	2	+	27869803	HPAFII	viability after 15 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.10542516692962556	[91]	[151,77,NaN]	1	hSpCas9	negative selection	9658006
70224616	70224639	2	-	27869803	HPAFII	viability after 15 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	-0.2930250391001938	[273]	[219,252,NaN]	-3	hSpCas9	negative selection	9658007
70225343	70225366	2	+	27869803	HPAFII	viability after 15 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.612018222641462	[465]	[844,715,NaN]	7	hSpCas9	negative selection	9658008
70229063	70229086	2	+	27869803	HPAFII	viability after 15 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.44348950163542844	[446]	[968,456,NaN]	5	hSpCas9	negative selection	9658009
70214371	70214394	2	-	27869803	ASPC1	viability after 36 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	1.9003988343854592	[354]	[166,162,902]	9	hSpCas9	negative selection	9740453
70215360	70215383	2	+	27869803	ASPC1	viability after 36 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.21457277341652842	[486]	[216,140,225]	2	hSpCas9	negative selection	9740454
70216891	70216914	2	+	27869803	ASPC1	viability after 36 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	1.1233398286139475	[267]	[214,195,199]	9	hSpCas9	negative selection	9740455
70224616	70224639	2	-	27869803	ASPC1	viability after 36 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.6275687212161887	[718]	[473,421,295]	6	hSpCas9	negative selection	9740456
70225343	70225366	2	+	27869803	ASPC1	viability after 36 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	-0.45374769859684877	[1188]	[468,421,88]	-4	hSpCas9	negative selection	9740457
70229063	70229086	2	+	27869803	ASPC1	viability after 36 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	-0.04024702981626116	[1304]	[486,687,212]	0	hSpCas9	negative selection	9740458
70214371	70214394	2	-	27869803	PATU8988S	viability after 35 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	-0.2980125554966825	[373]	[129,114,NaN]	-3	hSpCas9	negative selection	9822902
70215360	70215383	2	+	27869803	PATU8988S	viability after 35 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.006457170090032771	[432]	[250,98,NaN]	0	hSpCas9	negative selection	9822903
70216891	70216914	2	+	27869803	PATU8988S	viability after 35 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.8691600444972258	[244]	[62,44,NaN]	-7	hSpCas9	negative selection	9822904
70224616	70224639	2	-	27869803	PATU8988S	viability after 35 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	-0.13664092194712704	[511]	[219,154,NaN]	-1	hSpCas9	negative selection	9822905
70225343	70225366	2	+	27869803	PATU8988S	viability after 35 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.0731518652481653	[848]	[236,482,NaN]	0	hSpCas9	negative selection	9822906
70229063	70229086	2	+	27869803	PATU8988S	viability after 35 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.5103542680101948	[1072]	[639,590,NaN]	6	hSpCas9	negative selection	9822907
70214371	70214394	2	-	27869803	PATU8988S	viability after 31 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	-0.25555927154270053	[373]	[127,120,NaN]	-3	hSpCas9	negative selection	9905351
70215360	70215383	2	+	27869803	PATU8988S	viability after 31 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.02305849068503929	[432]	[163,189,NaN]	0	hSpCas9	negative selection	9905352
70216891	70216914	2	+	27869803	PATU8988S	viability after 31 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.544960713149355	[244]	[62,71,NaN]	-5	hSpCas9	negative selection	9905353
70224616	70224639	2	-	27869803	PATU8988S	viability after 31 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	0.14875800092182329	[511]	[279,157,NaN]	1	hSpCas9	negative selection	9905354
70225343	70225366	2	+	27869803	PATU8988S	viability after 31 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	0.26906330213187224	[848]	[315,524,NaN]	3	hSpCas9	negative selection	9905355
70229063	70229086	2	+	27869803	PATU8988S	viability after 31 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.5434910627125965	[1072]	[583,673,NaN]	6	hSpCas9	negative selection	9905356
70214371	70214394	2	-	27869803	HPAFII	viability after 35 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	0.45357155292137985	[173]	[201,28,NaN]	3	hSpCas9	negative selection	9987800
70215360	70215383	2	+	27869803	HPAFII	viability after 35 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-1.587182235315604	[222]	[6,71,NaN]	-7	hSpCas9	negative selection	9987801
70216891	70216914	2	+	27869803	HPAFII	viability after 35 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	1.0097751020431034	[91]	[129,52,NaN]	6	hSpCas9	negative selection	9987802
70224616	70224639	2	-	27869803	HPAFII	viability after 35 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	-1.0613901506959833	[273]	[57,75,NaN]	-6	hSpCas9	negative selection	9987803
70225343	70225366	2	+	27869803	HPAFII	viability after 35 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	1.4630665670027971	[465]	[370,964,NaN]	8	hSpCas9	negative selection	9987804
70229063	70229086	2	+	27869803	HPAFII	viability after 35 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	1.153482689069389	[446]	[572,424,NaN]	7	hSpCas9	negative selection	9987805
70214371	70214394	2	-	27869803	HPAFII	viability after 31 days	TGCATATGGAATGTATGGCCAGG	TIA1	ENSG00000116001	0.809484974557711	[173]	[285,45,NaN]	6	hSpCas9	negative selection	10070249
70215360	70215383	2	+	27869803	HPAFII	viability after 31 days	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-2.0374672563655882	[222]	[18,42,NaN]	-8	hSpCas9	negative selection	10070250
70216891	70216914	2	+	27869803	HPAFII	viability after 31 days	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.9425967690981282	[91]	[137,56,NaN]	7	hSpCas9	negative selection	10070251
70224616	70224639	2	-	27869803	HPAFII	viability after 31 days	TGATTTCAGAGATGCCCGAGTGG	TIA1	ENSG00000116001	-0.9426039820908801	[273]	[68,91,NaN]	-5	hSpCas9	negative selection	10070252
70225343	70225366	2	+	27869803	HPAFII	viability after 31 days	ACCGTAGCTTGTAGTTAGCCAGG	TIA1	ENSG00000116001	1.1540426916959032	[465]	[525,642,NaN]	8	hSpCas9	negative selection	10070253
70229063	70229086	2	+	27869803	HPAFII	viability after 31 days	TGAACGCTGTGTGCTGACAACGG	TIA1	ENSG00000116001	0.834316088275043	[446]	[531,354,NaN]	6	hSpCas9	negative selection	10070254
70227793	70227816	2	+	28162770	P31FUJ	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	0.1822352948644652	[32]	[43]	2	hSpCas9	negative selection	10250538
70215360	70215383	2	+	28162770	P31FUJ	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.501216105701491	[587]	[977]	5	hSpCas9	negative selection	10250539
70216963	70216986	2	-	28162770	P31FUJ	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	0.3997783165395173	[148]	[230]	4	hSpCas9	negative selection	10250540
70214452	70214475	2	+	28162770	P31FUJ	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	-0.6148892818919358	[201]	[154]	-5	hSpCas9	negative selection	10250541
70214431	70214454	2	+	28162770	P31FUJ	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	0.39026490133227965	[273]	[421]	4	hSpCas9	negative selection	10250542
70216427	70216450	2	-	28162770	P31FUJ	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	0.3059901148738515	[253]	[368]	3	hSpCas9	negative selection	10250543
70248392	70248415	2	+	28162770	P31FUJ	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.5161885551292369	[453]	[762]	6	hSpCas9	negative selection	10250544
70216891	70216914	2	+	28162770	P31FUJ	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.9319425579222536	[123]	[277]	9	hSpCas9	negative selection	10250545
70224604	70224627	2	-	28162770	P31FUJ	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	-0.044833613681455886	[308]	[351]	0	hSpCas9	negative selection	10250546
70224579	70224602	2	-	28162770	P31FUJ	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	0.440889214901109	[535]	[854]	5	hSpCas9	negative selection	10250547
70227793	70227816	2	+	28162770	TF1	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10419904
70215360	70215383	2	+	28162770	TF1	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	NaN	[NaN]	[830]	1	hSpCas9	negative selection	10419905
70216963	70216986	2	-	28162770	TF1	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10419906
70214452	70214475	2	+	28162770	TF1	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10419907
70214431	70214454	2	+	28162770	TF1	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	NaN	[NaN]	[327]	1	hSpCas9	negative selection	10419908
70216427	70216450	2	-	28162770	TF1	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	NaN	[NaN]	[423]	1	hSpCas9	negative selection	10419909
70248392	70248415	2	+	28162770	TF1	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	NaN	[NaN]	[693]	1	hSpCas9	negative selection	10419910
70216891	70216914	2	+	28162770	TF1	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10419911
70224604	70224627	2	-	28162770	TF1	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	NaN	[NaN]	[268]	1	hSpCas9	negative selection	10419912
70224579	70224602	2	-	28162770	TF1	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	NaN	[NaN]	[693]	1	hSpCas9	negative selection	10419913
70227793	70227816	2	+	28162770	SKM1	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	-0.014646775964401115	[23]	[41]	0	hSpCas9	negative selection	10589270
70215360	70215383	2	+	28162770	SKM1	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.1831785410836746	[138]	[278]	1	hSpCas9	negative selection	10589271
70216963	70216986	2	-	28162770	SKM1	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	1.3230486347812775	[25]	[114]	9	hSpCas9	negative selection	10589272
70214452	70214475	2	+	28162770	SKM1	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	-0.8678053876351302	[63]	[61]	-6	hSpCas9	negative selection	10589273
70214431	70214454	2	+	28162770	SKM1	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	-0.4863986662375666	[83]	[105]	-4	hSpCas9	negative selection	10589274
70216427	70216450	2	-	28162770	SKM1	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	-0.1713359502500198	[92]	[145]	-1	hSpCas9	negative selection	10589275
70248392	70248415	2	+	28162770	SKM1	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.38444917944542056	[116]	[269]	4	hSpCas9	negative selection	10589276
70216891	70216914	2	+	28162770	SKM1	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.01930055595893654	[23]	[42]	0	hSpCas9	negative selection	10589277
70224604	70224627	2	-	28162770	SKM1	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.771088683582551	[58]	[177]	7	hSpCas9	negative selection	10589278
70224579	70224602	2	-	28162770	SKM1	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	-0.3506959790964167	[131]	[182]	-3	hSpCas9	negative selection	10589279
70227793	70227816	2	+	28162770	SKM1	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	-0.014646775964401115	[23]	[41]	0	hSpCas9	negative selection	10758636
70215360	70215383	2	+	28162770	SKM1	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.1831785410836746	[138]	[278]	1	hSpCas9	negative selection	10758637
70216963	70216986	2	-	28162770	SKM1	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	1.3230486347812775	[25]	[114]	9	hSpCas9	negative selection	10758638
70214452	70214475	2	+	28162770	SKM1	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	-0.8678053876351302	[63]	[61]	-6	hSpCas9	negative selection	10758639
70214431	70214454	2	+	28162770	SKM1	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	-0.4863986662375666	[83]	[105]	-4	hSpCas9	negative selection	10758640
70216427	70216450	2	-	28162770	SKM1	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	-0.1713359502500198	[92]	[145]	-1	hSpCas9	negative selection	10758641
70248392	70248415	2	+	28162770	SKM1	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.38444917944542056	[116]	[269]	4	hSpCas9	negative selection	10758642
70216891	70216914	2	+	28162770	SKM1	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.01930055595893654	[23]	[42]	0	hSpCas9	negative selection	10758643
70224604	70224627	2	-	28162770	SKM1	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.771088683582551	[58]	[177]	7	hSpCas9	negative selection	10758644
70224579	70224602	2	-	28162770	SKM1	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	-0.3506959790964167	[131]	[182]	-3	hSpCas9	negative selection	10758645
70227793	70227816	2	+	28162770	PL21	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	0.038676191795203874	[84]	[37]	0	hSpCas9	negative selection	10928002
70215360	70215383	2	+	28162770	PL21	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	1.2596045548039216	[403]	[420]	9	hSpCas9	negative selection	10928003
70216963	70216986	2	-	28162770	PL21	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	0.6092522798110586	[121]	[80]	5	hSpCas9	negative selection	10928004
70214452	70214475	2	+	28162770	PL21	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	-0.8066495511733189	[212]	[52]	-5	hSpCas9	negative selection	10928005
70214431	70214454	2	+	28162770	PL21	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	1.2216727760389614	[265]	[269]	8	hSpCas9	negative selection	10928006
70216427	70216450	2	-	28162770	PL21	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	-0.01439068907415697	[426]	[183]	0	hSpCas9	negative selection	10928007
70248392	70248415	2	+	28162770	PL21	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.20013961448932027	[347]	[173]	1	hSpCas9	negative selection	10928008
70216891	70216914	2	+	28162770	PL21	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.047787898954265495	[56]	[23]	0	hSpCas9	negative selection	10928009
70224604	70224627	2	-	28162770	PL21	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	-0.2363776121999751	[202]	[74]	-2	hSpCas9	negative selection	10928010
70224579	70224602	2	-	28162770	PL21	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	0.28877091376164965	[362]	[192]	2	hSpCas9	negative selection	10928011
70227793	70227816	2	+	28162770	P31FUJ	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	0.1822352948644652	[32]	[43]	2	hSpCas9	negative selection	11097368
70215360	70215383	2	+	28162770	P31FUJ	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.501216105701491	[587]	[977]	5	hSpCas9	negative selection	11097369
70216963	70216986	2	-	28162770	P31FUJ	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	0.3997783165395173	[148]	[230]	4	hSpCas9	negative selection	11097370
70214452	70214475	2	+	28162770	P31FUJ	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	-0.6148892818919358	[201]	[154]	-5	hSpCas9	negative selection	11097371
70214431	70214454	2	+	28162770	P31FUJ	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	0.39026490133227965	[273]	[421]	4	hSpCas9	negative selection	11097372
70216427	70216450	2	-	28162770	P31FUJ	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	0.3059901148738515	[253]	[368]	3	hSpCas9	negative selection	11097373
70248392	70248415	2	+	28162770	P31FUJ	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.5161885551292369	[453]	[762]	6	hSpCas9	negative selection	11097374
70216891	70216914	2	+	28162770	P31FUJ	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.9319425579222536	[123]	[277]	9	hSpCas9	negative selection	11097375
70224604	70224627	2	-	28162770	P31FUJ	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	-0.044833613681455886	[308]	[351]	0	hSpCas9	negative selection	11097376
70224579	70224602	2	-	28162770	P31FUJ	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	0.440889214901109	[535]	[854]	5	hSpCas9	negative selection	11097377
70227793	70227816	2	+	28162770	OCIAML5	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	-0.1999898742843037	[69]	[109]	-1	hSpCas9	negative selection	11266734
70215360	70215383	2	+	28162770	OCIAML5	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.9467078201147798	[264]	[921]	7	hSpCas9	negative selection	11266735
70216963	70216986	2	-	28162770	OCIAML5	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	-0.19998987428430393	[62]	[98]	-1	hSpCas9	negative selection	11266736
70214452	70214475	2	+	28162770	OCIAML5	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	0.3935106378932506	[96]	[229]	3	hSpCas9	negative selection	11266737
70214431	70214454	2	+	28162770	OCIAML5	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	-0.06309017812124734	[157]	[272]	0	hSpCas9	negative selection	11266738
70216427	70216450	2	-	28162770	OCIAML5	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	0.5231773385558217	[169]	[440]	4	hSpCas9	negative selection	11266739
70248392	70248415	2	+	28162770	OCIAML5	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.04143380783532402	[266]	[495]	0	hSpCas9	negative selection	11266740
70216891	70216914	2	+	28162770	OCIAML5	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.3513729870404447	[93]	[132]	-3	hSpCas9	negative selection	11266741
70224604	70224627	2	-	28162770	OCIAML5	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.5590452252010467	[137]	[366]	5	hSpCas9	negative selection	11266742
70224579	70224602	2	-	28162770	OCIAML5	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	1.7441817374036745	[190]	[1154]	9	hSpCas9	negative selection	11266743
70227793	70227816	2	+	28162770	EOL1	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	0.8102150960915396	[104]	[96]	7	hSpCas9	negative selection	11436100
70215360	70215383	2	+	28162770	EOL1	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.04861398851246146	[656]	[357]	0	hSpCas9	negative selection	11436101
70216963	70216986	2	-	28162770	EOL1	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	1.246475866457897	[255]	[319]	9	hSpCas9	negative selection	11436102
70214452	70214475	2	+	28162770	EOL1	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	0.4763102219733538	[336]	[246]	4	hSpCas9	negative selection	11436103
70214431	70214454	2	+	28162770	EOL1	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	0.09249240888460619	[485]	[272]	0	hSpCas9	negative selection	11436104
70216427	70216450	2	-	28162770	EOL1	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	0.5786687502159671	[576]	[453]	5	hSpCas9	negative selection	11436105
70248392	70248415	2	+	28162770	EOL1	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	1.1164034130823495	[456]	[521]	8	hSpCas9	negative selection	11436106
70216891	70216914	2	+	28162770	EOL1	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	-0.17329955182761037	[121]	[56]	-1	hSpCas9	negative selection	11436107
70224604	70224627	2	-	28162770	EOL1	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.9716329076402757	[210]	[217]	8	hSpCas9	negative selection	11436108
70224579	70224602	2	-	28162770	EOL1	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	0.07378972533852757	[522]	[289]	0	hSpCas9	negative selection	11436109
70227793	70227816	2	+	28162770	MOLM13	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	-0.8604364845409342	[112]	[44]	-5	hSpCas9	negative selection	11605466
70215360	70215383	2	+	28162770	MOLM13	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.5402114345373592	[816]	[858]	4	hSpCas9	negative selection	11605467
70216963	70216986	2	-	28162770	MOLM13	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	0.545891893545852	[197]	[208]	4	hSpCas9	negative selection	11605468
70214452	70214475	2	+	28162770	MOLM13	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	0.4993676130177467	[271]	[277]	4	hSpCas9	negative selection	11605469
70214431	70214454	2	+	28162770	MOLM13	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	-0.3683483561615999	[390]	[218]	-2	hSpCas9	negative selection	11605470
70216427	70216450	2	-	28162770	MOLM13	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	0.2607533010051938	[485]	[420]	1	hSpCas9	negative selection	11605471
70248392	70248415	2	+	28162770	MOLM13	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	1.1470134527723261	[513]	[822]	8	hSpCas9	negative selection	11605472
70216891	70216914	2	+	28162770	MOLM13	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.27028942165941805	[124]	[108]	2	hSpCas9	negative selection	11605473
70224604	70224627	2	-	28162770	MOLM13	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	-0.746429739256187	[296]	[127]	-4	hSpCas9	negative selection	11605474
70224579	70224602	2	-	28162770	MOLM13	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	0.6169808795697258	[495]	[549]	4	hSpCas9	negative selection	11605475
70227793	70227816	2	+	28162770	HEL	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	-1.1309853121759668	[105]	[30]	-6	hSpCas9	negative selection	11774832
70215360	70215383	2	+	28162770	HEL	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.7011144046752593	[556]	[579]	6	hSpCas9	negative selection	11774833
70216963	70216986	2	-	28162770	HEL	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	0.27661093320245944	[173]	[134]	2	hSpCas9	negative selection	11774834
70214452	70214475	2	+	28162770	HEL	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	0.41073132178718763	[275]	[234]	3	hSpCas9	negative selection	11774835
70214431	70214454	2	+	28162770	HEL	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	0.9156210237904979	[364]	[440]	7	hSpCas9	negative selection	11774836
70216427	70216450	2	-	28162770	HEL	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	0.8716445602954793	[441]	[517]	7	hSpCas9	negative selection	11774837
70248392	70248415	2	+	28162770	HEL	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.6394931724967029	[444]	[443]	5	hSpCas9	negative selection	11774838
70216891	70216914	2	+	28162770	HEL	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.47767958572986047	[110]	[98]	4	hSpCas9	negative selection	11774839
70224604	70224627	2	-	28162770	HEL	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.2575718623036508	[238]	[182]	2	hSpCas9	negative selection	11774840
70224579	70224602	2	-	28162770	HEL	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	0.43095451022988995	[541]	[467]	3	hSpCas9	negative selection	11774841
70227793	70227816	2	+	28162770	MV411	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	-0.41152553138215797	[59]	[37]	-3	hSpCas9	negative selection	11944198
70215360	70215383	2	+	28162770	MV411	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.5109686669127096	[483]	[580]	4	hSpCas9	negative selection	11944199
70216963	70216986	2	-	28162770	MV411	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	0.4752434683055876	[151]	[177]	4	hSpCas9	negative selection	11944200
70214452	70214475	2	+	28162770	MV411	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	-0.20894074387696804	[176]	[128]	-2	hSpCas9	negative selection	11944201
70214431	70214454	2	+	28162770	MV411	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	0.3679328429693358	[286]	[311]	3	hSpCas9	negative selection	11944202
70216427	70216450	2	-	28162770	MV411	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	-0.5257915873702025	[375]	[219]	-4	hSpCas9	negative selection	11944203
70248392	70248415	2	+	28162770	MV411	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.26648330647332186	[300]	[304]	2	hSpCas9	negative selection	11944204
70216891	70216914	2	+	28162770	MV411	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	1.5127821173037703	[51]	[124]	9	hSpCas9	negative selection	11944205
70224604	70224627	2	-	28162770	MV411	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.030285582142207557	[228]	[196]	0	hSpCas9	negative selection	11944206
70224579	70224602	2	-	28162770	MV411	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	0.36942807516138587	[373]	[406]	3	hSpCas9	negative selection	11944207
70227793	70227816	2	+	28162770	MONOMAC1	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	-1.6665221303607738	[35]	[12]	-8	hSpCas9	negative selection	12113564
70215360	70215383	2	+	28162770	MONOMAC1	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	0.2721172010109866	[241]	[334]	2	hSpCas9	negative selection	12113565
70216963	70216986	2	-	28162770	MONOMAC1	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	-0.14581152370438055	[82]	[85]	-1	hSpCas9	negative selection	12113566
70214452	70214475	2	+	28162770	MONOMAC1	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	-0.7559101189120491	[136]	[92]	-6	hSpCas9	negative selection	12113567
70214431	70214454	2	+	28162770	MONOMAC1	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	-0.5644932818042878	[168]	[130]	-5	hSpCas9	negative selection	12113568
70216427	70216450	2	-	28162770	MONOMAC1	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	-0.6044611622285225	[251]	[189]	-5	hSpCas9	negative selection	12113569
70248392	70248415	2	+	28162770	MONOMAC1	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	-0.0062813503183758446	[190]	[217]	0	hSpCas9	negative selection	12113570
70216891	70216914	2	+	28162770	MONOMAC1	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.2007226607874545	[62]	[82]	2	hSpCas9	negative selection	12113571
70224604	70224627	2	-	28162770	MONOMAC1	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.4265872740307074	[134]	[207]	4	hSpCas9	negative selection	12113572
70224579	70224602	2	-	28162770	MONOMAC1	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	-0.6003925412907622	[245]	[185]	-5	hSpCas9	negative selection	12113573
70227793	70227816	2	+	28162770	OCIAML2	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	-0.4986442014117578	[12]	[50]	-4	hSpCas9	negative selection	12282930
70215360	70215383	2	+	28162770	OCIAML2	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	-0.05969672429605399	[109]	[584]	0	hSpCas9	negative selection	12282931
70216963	70216986	2	-	28162770	OCIAML2	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	0.004149757728571998	[33]	[188]	0	hSpCas9	negative selection	12282932
70214452	70214475	2	+	28162770	OCIAML2	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	0.13652842159319112	[42]	[261]	1	hSpCas9	negative selection	12282933
70214431	70214454	2	+	28162770	OCIAML2	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	0.16372070244115833	[66]	[415]	1	hSpCas9	negative selection	12282934
70216427	70216450	2	-	28162770	OCIAML2	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	0.736695148005345	[54]	[507]	7	hSpCas9	negative selection	12282935
70248392	70248415	2	+	28162770	OCIAML2	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	0.6586531917028055	[59]	[524]	6	hSpCas9	negative selection	12282936
70216891	70216914	2	+	28162770	OCIAML2	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.13942365644182542	[18]	[115]	1	hSpCas9	negative selection	12282937
70224604	70224627	2	-	28162770	OCIAML2	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.3100571463533628	[38]	[267]	3	hSpCas9	negative selection	12282938
70224579	70224602	2	-	28162770	OCIAML2	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	0.8857866460304918	[61]	[634]	8	hSpCas9	negative selection	12282939
70227793	70227816	2	+	28162770	OCIAML3	viability	TGAGATCACCAACAAAGACATGG	TIA1	ENSG00000116001	-1.594007640324163	[21]	[21]	-8	hSpCas9	negative selection	12452296
70215360	70215383	2	+	28162770	OCIAML3	viability	AACCCTCTCACCTGTTGCACGGG	TIA1	ENSG00000116001	1.086192657169918	[126]	[813]	8	hSpCas9	negative selection	12452297
70216963	70216986	2	-	28162770	OCIAML3	viability	AACGCCATTCAACAGATGGGTGG	TIA1	ENSG00000116001	0.5603205060671308	[30]	[137]	5	hSpCas9	negative selection	12452298
70214452	70214475	2	+	28162770	OCIAML3	viability	GGCCCCACTGGCCATAAGGTTGG	TIA1	ENSG00000116001	-1.5701608983697954	[59]	[60]	-8	hSpCas9	negative selection	12452299
70214431	70214454	2	+	28162770	OCIAML3	viability	GTTGTGCATTTCCATACCACTGG	TIA1	ENSG00000116001	-0.009045139603006791	[76]	[230]	0	hSpCas9	negative selection	12452300
70216427	70216450	2	-	28162770	OCIAML3	viability	AGCAACTGTACTGTATACTGTGG	TIA1	ENSG00000116001	0.018331299328298134	[86]	[265]	0	hSpCas9	negative selection	12452301
70248392	70248415	2	+	28162770	OCIAML3	viability	GCCCCAGACTCACAGAGTCTTGG	TIA1	ENSG00000116001	1.6592787889580685	[98]	[943]	9	hSpCas9	negative selection	12452302
70216891	70216914	2	+	28162770	OCIAML3	viability	TATGTACTCTTTGGAGCGGGAGG	TIA1	ENSG00000116001	0.5178852397467342	[30]	[133]	5	hSpCas9	negative selection	12452303
70224604	70224627	2	-	28162770	OCIAML3	viability	TGCCCGAGTGGTAAAAGACATGG	TIA1	ENSG00000116001	0.8654239783131339	[47]	[263]	7	hSpCas9	negative selection	12452304
70224579	70224602	2	-	28162770	OCIAML3	viability	ACAGGAAAGTCTAAGGGATATGG	TIA1	ENSG00000116001	1.2942672771170085	[103]	[769]	9	hSpCas9	negative selection	12452305