Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7075
• Symbol:TIE1
• Description:tyrosine kinase with immunoglobulin like and EGF like domains 1

DataSource: http://genomecrispr.dkfz.de/#!/results/TIE1

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
43317230	43317253	1	+	26472758	Jiyoye	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	-0.07560672440880462	[108]	[77]	0	hSpCas9	negative selection	165477
43311717	43311740	1	-	26472758	Jiyoye	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	5.494638222756212	[0]	[33]	9	hSpCas9	negative selection	165478
43304900	43304923	1	-	26472758	Jiyoye	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	1.279167769129802	[52]	[96]	7	hSpCas9	negative selection	165479
43305281	43305304	1	-	26472758	Jiyoye	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	1.4071753815058732	[32]	[65]	8	hSpCas9	negative selection	165480
43307242	43307265	1	-	26472758	Jiyoye	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	-0.11638657455113958	[114]	[79]	-1	hSpCas9	negative selection	165481
43307499	43307522	1	-	26472758	Jiyoye	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-2.1430217010546064	[40]	[6]	-8	hSpCas9	negative selection	165482
43307887	43307910	1	-	26472758	Jiyoye	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	1.4004180153305645	[106]	[212]	8	hSpCas9	negative selection	165483
43309045	43309068	1	-	26472758	Jiyoye	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	0.17656245336445686	[175]	[149]	1	hSpCas9	negative selection	165484
43309076	43309099	1	-	26472758	Jiyoye	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.5307500666244062	[122]	[133]	4	hSpCas9	negative selection	165485
43309419	43309442	1	-	26472758	Jiyoye	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	-0.6048974507947016	[239]	[118]	-4	hSpCas9	negative selection	165486
43317230	43317253	1	+	26472758	KBM7	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	0.8595109831840293	[392,216]	[304,207]	8	hSpCas9	negative selection	356595
43311717	43311740	1	-	26472758	KBM7	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	-0.6047263705046645	[321,233]	[56,109]	-5	hSpCas9	negative selection	356596
43304900	43304923	1	-	26472758	KBM7	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	1.3319434146946372	[295,279]	[424,266]	9	hSpCas9	negative selection	356597
43305281	43305304	1	-	26472758	KBM7	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	0.32541940892720106	[458,439]	[226,299]	3	hSpCas9	negative selection	356598
43307242	43307265	1	-	26472758	KBM7	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	0.4178349136125642	[483,278]	[182,279]	4	hSpCas9	negative selection	356599
43307499	43307522	1	-	26472758	KBM7	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-1.0199704569557455	[192,221]	[63,34]	-7	hSpCas9	negative selection	356600
43307887	43307910	1	-	26472758	KBM7	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	0.2676222584042488	[980,896]	[509,550]	2	hSpCas9	negative selection	356601
43309045	43309068	1	-	26472758	KBM7	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-0.2152459413540616	[1071,794]	[398,351]	-2	hSpCas9	negative selection	356602
43309076	43309099	1	-	26472758	KBM7	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.7563799594692692	[458,491]	[260,487]	8	hSpCas9	negative selection	356603
43309419	43309442	1	-	26472758	KBM7	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	0.2650687079974779	[620,534]	[274,370]	2	hSpCas9	negative selection	356604
43317230	43317253	1	+	26472758	Raji	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	0.39550892217022365	[189]	[57]	4	hSpCas9	negative selection	547713
43311717	43311740	1	-	26472758	Raji	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	-0.937010583984854	[230]	[27]	-6	hSpCas9	negative selection	547714
43304900	43304923	1	-	26472758	Raji	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.8695197052747117	[124]	[52]	7	hSpCas9	negative selection	547715
43305281	43305304	1	-	26472758	Raji	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	-0.3407622757171828	[190]	[34]	-3	hSpCas9	negative selection	547716
43307242	43307265	1	-	26472758	Raji	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	0.601855502146848	[158]	[55]	5	hSpCas9	negative selection	547717
43307499	43307522	1	-	26472758	Raji	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-4.750597459753973	[115]	[0]	-9	hSpCas9	negative selection	547718
43307887	43307910	1	-	26472758	Raji	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	1.0508000070072319	[415]	[199]	8	hSpCas9	negative selection	547719
43309045	43309068	1	-	26472758	Raji	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-0.011354011209923298	[442]	[101]	0	hSpCas9	negative selection	547720
43309076	43309099	1	-	26472758	Raji	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	-0.24757335990123341	[485]	[94]	-2	hSpCas9	negative selection	547721
43309419	43309442	1	-	26472758	Raji	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	0.7336530102516693	[240]	[92]	7	hSpCas9	negative selection	547722
43317230	43317253	1	+	26472758	K562	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	-1.210634450460276	[328]	[119]	-6	hSpCas9	negative selection	738831
43311717	43311740	1	-	26472758	K562	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	-0.33276642246299004	[184]	[123]	-2	hSpCas9	negative selection	738832
43304900	43304923	1	-	26472758	K562	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.056346379513875056	[269]	[236]	0	hSpCas9	negative selection	738833
43305281	43305304	1	-	26472758	K562	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	0.38537965031991184	[340]	[375]	3	hSpCas9	negative selection	738834
43307242	43307265	1	-	26472758	K562	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	0.8221314893082149	[265]	[396]	6	hSpCas9	negative selection	738835
43307499	43307522	1	-	26472758	K562	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-7.810863707834742	[265]	[0]	-9	hSpCas9	negative selection	738836
43307887	43307910	1	-	26472758	K562	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	-0.32832782334507016	[881]	[592]	-2	hSpCas9	negative selection	738837
43309045	43309068	1	-	26472758	K562	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	0.5819566590107772	[716]	[905]	5	hSpCas9	negative selection	738838
43309076	43309099	1	-	26472758	K562	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.9890661075556001	[486]	[815]	8	hSpCas9	negative selection	738839
43309419	43309442	1	-	26472758	K562	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	-0.34054377305470934	[467]	[311]	-2	hSpCas9	negative selection	738840
43301107	43301130	1	-	26627737	DLD1	viability	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.08991892616390862	[813]	[304,328,192]	0	hSpCas9	negative selection	771512
43305141	43305164	1	+	26627737	DLD1	viability	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	-0.9052988306419143	[580]	[73,62,144]	-7	hSpCas9	negative selection	771513
43306959	43306982	1	-	26627737	DLD1	viability	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-0.6178880171166454	[542]	[103,110,115]	-6	hSpCas9	negative selection	771514
43307186	43307209	1	-	26627737	DLD1	viability	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	-0.2080601652068942	[759]	[360,125,136]	-2	hSpCas9	negative selection	771515
43307559	43307582	1	-	26627737	DLD1	viability	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	-0.7367822316475385	[500]	[63,105,109]	-6	hSpCas9	negative selection	771516
43307833	43307856	1	-	26627737	DLD1	viability	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.4147713311110275	[1101]	[523,538,336]	4	hSpCas9	negative selection	771517
43301107	43301130	1	-	26627737	GBM cells	viability after 5 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.01508539668443376	[798]	[421,443]	0	hSpCas9	negative selection	853827
43305141	43305164	1	+	26627737	GBM cells	viability after 5 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	0.17596037109220378	[221]	[173,94]	2	hSpCas9	negative selection	853828
43306959	43306982	1	-	26627737	GBM cells	viability after 5 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-0.5161236243931584	[291]	[89,128]	-7	hSpCas9	negative selection	853829
43307186	43307209	1	-	26627737	GBM cells	viability after 5 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.1978634059949561	[442]	[265,278]	3	hSpCas9	negative selection	853830
43307559	43307582	1	-	26627737	GBM cells	viability after 5 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.012124485333676771	[195]	[122,88]	0	hSpCas9	negative selection	853831
43307833	43307856	1	-	26627737	GBM cells	viability after 5 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.07523664752614867	[399]	[209,241]	1	hSpCas9	negative selection	853832
43301107	43301130	1	-	26627737	GBM cells	viability after 13 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.1000200656436101	[798]	[655,308]	1	hSpCas9	negative selection	936142
43305141	43305164	1	+	26627737	GBM cells	viability after 13 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	0.07470041671250269	[221]	[106,142]	1	hSpCas9	negative selection	936143
43306959	43306982	1	-	26627737	GBM cells	viability after 13 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-0.2306701230241893	[291]	[182,95]	-3	hSpCas9	negative selection	936144
43307186	43307209	1	-	26627737	GBM cells	viability after 13 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.4409368928272209	[442]	[274,367]	5	hSpCas9	negative selection	936145
43307559	43307582	1	-	26627737	GBM cells	viability after 13 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.3453870677113513	[195]	[149,122]	4	hSpCas9	negative selection	936146
43307833	43307856	1	-	26627737	GBM cells	viability after 13 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.3346908066698666	[399]	[292,257]	4	hSpCas9	negative selection	936147
43301107	43301130	1	-	26627737	GBM cells	viability after 21 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	-0.24275007045150465	[798]	[381,352]	-2	hSpCas9	negative selection	1018457
43305141	43305164	1	+	26627737	GBM cells	viability after 21 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	0.0774022639973836	[221]	[132,121]	0	hSpCas9	negative selection	1018458
43306959	43306982	1	-	26627737	GBM cells	viability after 21 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	0.43613907976528665	[291]	[187,238]	4	hSpCas9	negative selection	1018459
43307186	43307209	1	-	26627737	GBM cells	viability after 21 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.5569476295449468	[442]	[375,333]	5	hSpCas9	negative selection	1018460
43307559	43307582	1	-	26627737	GBM cells	viability after 21 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	-0.161418504130258	[195]	[101,88]	-1	hSpCas9	negative selection	1018461
43307833	43307856	1	-	26627737	GBM cells	viability after 21 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.9642597574349385	[399]	[435,412]	8	hSpCas9	negative selection	1018462
43301107	43301130	1	-	26627737	RPE1	viability after 9 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	-0.36197022549428337	[2029]	[497,489]	-3	hSpCas9	negative selection	1100772
43305141	43305164	1	+	26627737	RPE1	viability after 9 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	-0.06704333306927701	[1010]	[216,411]	0	hSpCas9	negative selection	1100773
43306959	43306982	1	-	26627737	RPE1	viability after 9 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	0.5822871996332675	[406]	[140,254]	4	hSpCas9	negative selection	1100774
43307186	43307209	1	-	26627737	RPE1	viability after 9 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	1.2656103932152822	[892]	[755,563]	7	hSpCas9	negative selection	1100775
43307559	43307582	1	-	26627737	RPE1	viability after 9 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.8802321711294275	[454]	[204,335]	5	hSpCas9	negative selection	1100776
43307833	43307856	1	-	26627737	RPE1	viability after 9 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.5635099514133783	[1004]	[395,553]	4	hSpCas9	negative selection	1100777
43301107	43301130	1	-	26627737	RPE1	viability after 12 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.13938256268550164	[2029]	[403,808]	1	hSpCas9	negative selection	1183087
43305141	43305164	1	+	26627737	RPE1	viability after 12 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	-0.5073797550939604	[1010]	[91,295]	-3	hSpCas9	negative selection	1183088
43306959	43306982	1	-	26627737	RPE1	viability after 12 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	1.0519579181844685	[406]	[199,254]	6	hSpCas9	negative selection	1183089
43307186	43307209	1	-	26627737	RPE1	viability after 12 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	1.2143142974473964	[892]	[613,495]	7	hSpCas9	negative selection	1183090
43307559	43307582	1	-	26627737	RPE1	viability after 12 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	1.0195873875052157	[454]	[190,307]	6	hSpCas9	negative selection	1183091
43307833	43307856	1	-	26627737	RPE1	viability after 12 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.7497709026804222	[1004]	[369,542]	5	hSpCas9	negative selection	1183092
43301107	43301130	1	-	26627737	RPE1	viability after 15 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.009291950611745259	[2029]	[664,493]	0	hSpCas9	negative selection	1265402
43305141	43305164	1	+	26627737	RPE1	viability after 15 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	-0.6263917716242904	[1010]	[57,307]	-4	hSpCas9	negative selection	1265403
43306959	43306982	1	-	26627737	RPE1	viability after 15 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	0.5193245706094547	[406]	[135,192]	3	hSpCas9	negative selection	1265404
43307186	43307209	1	-	26627737	RPE1	viability after 15 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	1.4155224766026995	[892]	[653,692]	7	hSpCas9	negative selection	1265405
43307559	43307582	1	-	26627737	RPE1	viability after 15 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	1.6260979771356308	[454]	[239,548]	8	hSpCas9	negative selection	1265406
43307833	43307856	1	-	26627737	RPE1	viability after 15 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.7511373809255975	[1004]	[562,396]	4	hSpCas9	negative selection	1265407
43301107	43301130	1	-	26627737	RPE1	viability after 18 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	-0.2273479160505223	[2029]	[393,546]	-1	hSpCas9	negative selection	1347717
43305141	43305164	1	+	26627737	RPE1	viability after 18 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	-0.3124675047433702	[1010]	[79,368]	-2	hSpCas9	negative selection	1347718
43306959	43306982	1	-	26627737	RPE1	viability after 18 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	0.9651229496088279	[406]	[255,169]	6	hSpCas9	negative selection	1347719
43307186	43307209	1	-	26627737	RPE1	viability after 18 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	1.4075514449831037	[892]	[604,675]	7	hSpCas9	negative selection	1347720
43307559	43307582	1	-	26627737	RPE1	viability after 18 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	1.555213285757123	[454]	[239,489]	7	hSpCas9	negative selection	1347721
43307833	43307856	1	-	26627737	RPE1	viability after 18 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	1.0758543803012208	[1004]	[548,595]	6	hSpCas9	negative selection	1347722
43301107	43301130	1	-	26627737	HeLa	viability after 8 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.2850915048225531	[1108]	[624,571,575]	2	hSpCas9	negative selection	1430032
43305141	43305164	1	+	26627737	HeLa	viability after 8 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	-0.5044582990342885	[327]	[48,44,189]	-5	hSpCas9	negative selection	1430033
43306959	43306982	1	-	26627737	HeLa	viability after 8 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-0.3323999579689708	[448]	[261,115,113]	-3	hSpCas9	negative selection	1430034
43307186	43307209	1	-	26627737	HeLa	viability after 8 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.6259134461975036	[535]	[260,377,414]	5	hSpCas9	negative selection	1430035
43307559	43307582	1	-	26627737	HeLa	viability after 8 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.24221485716280622	[468]	[338,303,111]	2	hSpCas9	negative selection	1430036
43307833	43307856	1	-	26627737	HeLa	viability after 8 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	-0.24404209588752146	[916]	[168,455,347]	-2	hSpCas9	negative selection	1430037
43301107	43301130	1	-	26627737	HeLa	viability after 12 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	-0.04278642295079216	[1108]	[348,538,433]	0	hSpCas9	negative selection	1512347
43305141	43305164	1	+	26627737	HeLa	viability after 12 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	-0.30657898491538144	[327]	[46,250,13]	-3	hSpCas9	negative selection	1512348
43306959	43306982	1	-	26627737	HeLa	viability after 12 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-1.2092177139492053	[448]	[28,129,74]	-8	hSpCas9	negative selection	1512349
43307186	43307209	1	-	26627737	HeLa	viability after 12 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.05082201871382591	[535]	[222,164,306]	0	hSpCas9	negative selection	1512350
43307559	43307582	1	-	26627737	HeLa	viability after 12 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	-0.6227533456801222	[468]	[173,59,151]	-5	hSpCas9	negative selection	1512351
43307833	43307856	1	-	26627737	HeLa	viability after 12 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	-0.48436490490841533	[916]	[457,252,108]	-4	hSpCas9	negative selection	1512352
43301107	43301130	1	-	26627737	HeLa	viability after 15 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.34669536788448796	[1108]	[575,696,438]	3	hSpCas9	negative selection	1594662
43305141	43305164	1	+	26627737	HeLa	viability after 15 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	0.4914067504942221	[327]	[158,198,206]	4	hSpCas9	negative selection	1594663
43306959	43306982	1	-	26627737	HeLa	viability after 15 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-0.5921158935000805	[448]	[85,50,235]	-5	hSpCas9	negative selection	1594664
43307186	43307209	1	-	26627737	HeLa	viability after 15 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.730059554773208	[535]	[274,231,597]	6	hSpCas9	negative selection	1594665
43307559	43307582	1	-	26627737	HeLa	viability after 15 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	-0.7061598766384662	[468]	[202,65,77]	-6	hSpCas9	negative selection	1594666
43307833	43307856	1	-	26627737	HeLa	viability after 15 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	-0.2581208577336166	[916]	[197,414,325]	-2	hSpCas9	negative selection	1594667
43301107	43301130	1	-	26627737	HeLa	viability after 18 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.34903894983350403	[1108]	[381,584,438]	3	hSpCas9	negative selection	1676977
43305141	43305164	1	+	26627737	HeLa	viability after 18 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	0.5261281955590672	[327]	[116,162,206]	4	hSpCas9	negative selection	1676978
43306959	43306982	1	-	26627737	HeLa	viability after 18 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-0.5792469071574367	[448]	[59,41,235]	-5	hSpCas9	negative selection	1676979
43307186	43307209	1	-	26627737	HeLa	viability after 18 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.7451491478074004	[535]	[187,196,597]	6	hSpCas9	negative selection	1676980
43307559	43307582	1	-	26627737	HeLa	viability after 18 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	-0.7261094770746455	[468]	[131,55,77]	-6	hSpCas9	negative selection	1676981
43307833	43307856	1	-	26627737	HeLa	viability after 18 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	-0.26755129288405155	[916]	[126,345,325]	-2	hSpCas9	negative selection	1676982
43301107	43301130	1	-	26627737	HCT116	viability after 6 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	-0.030793578346385297	[1124]	[234,138]	0	hSpCas9	negative selection	1759292
43305141	43305164	1	+	26627737	HCT116	viability after 6 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	0.6206911775294363	[539]	[281,46]	3	hSpCas9	negative selection	1759293
43306959	43306982	1	-	26627737	HCT116	viability after 6 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	1.3632535474677325	[409]	[315,82]	7	hSpCas9	negative selection	1759294
43307186	43307209	1	-	26627737	HCT116	viability after 6 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	-0.7569092628575103	[1040]	[237,18]	-4	hSpCas9	negative selection	1759295
43307559	43307582	1	-	26627737	HCT116	viability after 6 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	2.3599938173058055	[315]	[488,125]	9	hSpCas9	negative selection	1759296
43307833	43307856	1	-	26627737	HCT116	viability after 6 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	-0.26962411866681985	[919]	[128,114]	-1	hSpCas9	negative selection	1759297
43301107	43301130	1	-	26627737	HCT116	viability after 8 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	-0.1813212516536442	[796]	[413,329,417]	-2	hSpCas9	negative selection	1841607
43305141	43305164	1	+	26627737	HCT116	viability after 8 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	0.24386874231787348	[224]	[158,162,118]	2	hSpCas9	negative selection	1841608
43306959	43306982	1	-	26627737	HCT116	viability after 8 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	0.24625780498187116	[399]	[206,204,369]	2	hSpCas9	negative selection	1841609
43307186	43307209	1	-	26627737	HCT116	viability after 8 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.4962610177428405	[365]	[355,238,259]	5	hSpCas9	negative selection	1841610
43307559	43307582	1	-	26627737	HCT116	viability after 8 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	-0.022478242592109343	[239]	[112,204,72]	0	hSpCas9	negative selection	1841611
43307833	43307856	1	-	26627737	HCT116	viability after 8 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	1.1440904778844274	[266]	[393,282,299]	8	hSpCas9	negative selection	1841612
43301107	43301130	1	-	26627737	HCT116	viability after 9 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.45537088664606584	[1124]	[350,459]	3	hSpCas9	negative selection	1923922
43305141	43305164	1	+	26627737	HCT116	viability after 9 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	0.08810828963803392	[539]	[164,143]	0	hSpCas9	negative selection	1923923
43306959	43306982	1	-	26627737	HCT116	viability after 9 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	1.2246463547617936	[409]	[242,265]	7	hSpCas9	negative selection	1923924
43307186	43307209	1	-	26627737	HCT116	viability after 9 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.6649858657216308	[1040]	[552,351]	5	hSpCas9	negative selection	1923925
43307559	43307582	1	-	26627737	HCT116	viability after 9 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	1.677928381069305	[315]	[479,103]	8	hSpCas9	negative selection	1923926
43307833	43307856	1	-	26627737	HCT116	viability after 9 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	1.0327252447561381	[919]	[434,555]	7	hSpCas9	negative selection	1923927
43301107	43301130	1	-	26627737	HCT116	viability after 12 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	-0.5489760664174761	[796]	[254,302,303]	-5	hSpCas9	negative selection	2006237
43305141	43305164	1	+	26627737	HCT116	viability after 12 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	0.3817959128171939	[224]	[189,110,156]	4	hSpCas9	negative selection	2006238
43306959	43306982	1	-	26627737	HCT116	viability after 12 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-0.5011137726461562	[399]	[194,127,117]	-5	hSpCas9	negative selection	2006239
43307186	43307209	1	-	26627737	HCT116	viability after 12 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.14705627127615956	[365]	[190,217,231]	1	hSpCas9	negative selection	2006240
43307559	43307582	1	-	26627737	HCT116	viability after 12 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.1733205598242538	[239]	[71,230,131]	1	hSpCas9	negative selection	2006241
43307833	43307856	1	-	26627737	HCT116	viability after 12 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	1.5866015050721487	[266]	[661,167,406]	9	hSpCas9	negative selection	2006242
43301107	43301130	1	-	26627737	HCT116	viability after 15 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	-0.43924258340793865	[796]	[471,295,261]	-4	hSpCas9	negative selection	2088552
43305141	43305164	1	+	26627737	HCT116	viability after 15 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	0.9593732044893314	[224]	[383,223,162]	7	hSpCas9	negative selection	2088553
43306959	43306982	1	-	26627737	HCT116	viability after 15 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-0.06348873366921248	[399]	[465,132,91]	0	hSpCas9	negative selection	2088554
43307186	43307209	1	-	26627737	HCT116	viability after 15 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.1737416147688492	[365]	[324,244,152]	1	hSpCas9	negative selection	2088555
43307559	43307582	1	-	26627737	HCT116	viability after 15 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.7001269140224071	[239]	[249,204,219]	6	hSpCas9	negative selection	2088556
43307833	43307856	1	-	26627737	HCT116	viability after 15 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	1.5970179526565	[266]	[851,301,286]	9	hSpCas9	negative selection	2088557
43301107	43301130	1	-	26627737	HCT116	viability after 18 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	-0.7521622272299197	[796]	[170,254,259]	-6	hSpCas9	negative selection	2170867
43305141	43305164	1	+	26627737	HCT116	viability after 18 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	1.6050025608522378	[224]	[500,343,137]	9	hSpCas9	negative selection	2170868
43306959	43306982	1	-	26627737	HCT116	viability after 18 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-0.8452247827010375	[399]	[139,67,117]	-7	hSpCas9	negative selection	2170869
43307186	43307209	1	-	26627737	HCT116	viability after 18 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	-0.13393575420311093	[365]	[118,90,283]	-1	hSpCas9	negative selection	2170870
43307559	43307582	1	-	26627737	HCT116	viability after 18 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.666285234122034	[239]	[230,116,209]	5	hSpCas9	negative selection	2170871
43307833	43307856	1	-	26627737	HCT116	viability after 18 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	1.86585046276762	[266]	[801,243,375]	9	hSpCas9	negative selection	2170872
43304972	43304995	1	-	24336569	HL60	viability	GGTCGTCCTTCTCCAGCAGCAGG	TIE1	ENSG00000066056	1.5079306464075204	[324]	[1955]	8	hSpCas9	negative selection	2300432
43305022	43305045	1	-	24336569	HL60	viability	ACCGTTGCGCGCCAGGCGCAGGG	TIE1	ENSG00000066056	0.4540450020018262	[365]	[1060]	4	hSpCas9	negative selection	2300433
43305029	43305052	1	-	24336569	HL60	viability	GGTGCGAACCGTTGCGCGCCAGG	TIE1	ENSG00000066056	-0.02879654269727694	[900]	[1868]	0	hSpCas9	negative selection	2300434
43305045	43305068	1	+	24336569	HL60	viability	TCGCACCAGGTCACGCTTCGCGG	TIE1	ENSG00000066056	0.5198896268265722	[845]	[2566]	4	hSpCas9	negative selection	2300435
43305050	43305073	1	-	24336569	HL60	viability	AGAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	0.5439902836644442	[444]	[1372]	5	hSpCas9	negative selection	2300436
43305062	43305085	1	+	24336569	HL60	viability	TCGCGGCTTCTCCAAGCCCTCGG	TIE1	ENSG00000066056	0.1438282112133464	[425]	[995]	1	hSpCas9	negative selection	2300437
43305071	43305094	1	+	24336569	HL60	viability	CTCCAAGCCCTCGGACCTCGTGG	TIE1	ENSG00000066056	0.6921271456714879	[1228]	[4201]	6	hSpCas9	negative selection	2300438
43305078	43305101	1	-	24336569	HL60	viability	AAGACGCCCACGAGGTCCGAGGG	TIE1	ENSG00000066056	-0.745180712764464	[879]	[1110]	-6	hSpCas9	negative selection	2300439
43305086	43305109	1	-	24336569	HL60	viability	CGCAGGAGAAGACGCCCACGAGG	TIE1	ENSG00000066056	0.6314050670537138	[808]	[2651]	5	hSpCas9	negative selection	2300440
43305093	43305116	1	+	24336569	HL60	viability	GGCGTCTTCTCCTGCGTGGGCGG	TIE1	ENSG00000066056	1.5971575073065047	[163]	[1049]	9	hSpCas9	negative selection	2300441
43304972	43304995	1	-	24336569	KBM7	viability	GGTCGTCCTTCTCCAGCAGCAGG	TIE1	ENSG00000066056	-0.03453574740212639	[723]	[1927]	0	hSpCas9	negative selection	2367609
43305022	43305045	1	-	24336569	KBM7	viability	ACCGTTGCGCGCCAGGCGCAGGG	TIE1	ENSG00000066056	0.8712513232550312	[372]	[1860]	7	hSpCas9	negative selection	2367610
43305029	43305052	1	-	24336569	KBM7	viability	GGTGCGAACCGTTGCGCGCCAGG	TIE1	ENSG00000066056	0.716876335840398	[645]	[2895]	6	hSpCas9	negative selection	2367611
43305045	43305068	1	+	24336569	KBM7	viability	TCGCACCAGGTCACGCTTCGCGG	TIE1	ENSG00000066056	1.367409050411149	[376]	[2652]	9	hSpCas9	negative selection	2367612
43305050	43305073	1	-	24336569	KBM7	viability	AGAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	0.3623954738968022	[392]	[1377]	3	hSpCas9	negative selection	2367613
43305062	43305085	1	+	24336569	KBM7	viability	TCGCGGCTTCTCCAAGCCCTCGG	TIE1	ENSG00000066056	-0.391622790574867	[530]	[1103]	-3	hSpCas9	negative selection	2367614
43305071	43305094	1	+	24336569	KBM7	viability	CTCCAAGCCCTCGGACCTCGTGG	TIE1	ENSG00000066056	0.857901056853843	[987]	[4883]	7	hSpCas9	negative selection	2367615
43305078	43305101	1	-	24336569	KBM7	viability	AAGACGCCCACGAGGTCCGAGGG	TIE1	ENSG00000066056	0.8706381245542201	[544]	[2717]	7	hSpCas9	negative selection	2367616
43305086	43305109	1	-	24336569	KBM7	viability	CGCAGGAGAAGACGCCCACGAGG	TIE1	ENSG00000066056	1.5992643207508892	[427]	[3536]	9	hSpCas9	negative selection	2367617
43305093	43305116	1	+	24336569	KBM7	viability	GGCGTCTTCTCCTGCGTGGGCGG	TIE1	ENSG00000066056	0.5909129614279902	[526]	[2164]	5	hSpCas9	negative selection	2367618
43313283	43313306	1	+	27013184	SW480	treatment with recombinant TRAIL	GATAGACGTGGACAGGCCTGAGG	TIE1	ENSG00000066056	2.6483172735999894	[208,185]	[683,327]	9	hSpCas9	positive selection	2954788
43313305	43313328	1	+	27013184	SW480	treatment with recombinant TRAIL	GAGACAAGCACCATCATCCGTGG	TIE1	ENSG00000066056	-0.024204250472208644	[478,1052]	[260,389]	0	hSpCas9	positive selection	2954789
43313355	43313378	1	+	27013184	SW480	treatment with recombinant TRAIL	CCGCATGCGGGCCAGCATTCAGG	TIE1	ENSG00000066056	0.6739978378739899	[208,315]	[207,133]	3	hSpCas9	positive selection	2954790
43313356	43313379	1	+	27013184	SW480	treatment with recombinant TRAIL	CGCATGCGGGCCAGCATTCAGGG	TIE1	ENSG00000066056	1.3547501482835902	[85,124]	[116,110]	6	hSpCas9	positive selection	2954791
43307212	43307235	1	-	27013184	SW480	treatment with recombinant TRAIL	CACATTCGCCGTCATGGTCGTGG	TIE1	ENSG00000066056	0.7202927195918991	[468,799]	[412,479]	3	hSpCas9	positive selection	2954792
43307218	43307241	1	-	27013184	SW480	treatment with recombinant TRAIL	GGCATACACATTCGCCGTCATGG	TIE1	ENSG00000066056	1.7561288966879836	[26,29]	[42,38]	7	hSpCas9	positive selection	2954793
43307259	43307282	1	-	27013184	SW480	treatment with recombinant TRAIL	CTCCTTACCCTGTTCACAGCGGG	TIE1	ENSG00000066056	1.8826505228127468	[262,550]	[415,927]	8	hSpCas9	positive selection	2954794
43313357	43313380	1	+	27013184	SW480	treatment with recombinant TRAIL	GCATGCGGGCCAGCATTCAGGGG	TIE1	ENSG00000066056	1.319786308809099	[653,673]	[495,1024]	6	hSpCas9	positive selection	2954795
43313362	43313385	1	+	27013184	SW480	treatment with recombinant TRAIL	CGGGCCAGCATTCAGGGGCTCGG	TIE1	ENSG00000066056	0.2223601850054568	[231,226]	[87,154]	1	hSpCas9	positive selection	2954796
43313363	43313386	1	+	27013184	SW480	treatment with recombinant TRAIL	GGGCCAGCATTCAGGGGCTCGGG	TIE1	ENSG00000066056	1.5611394923415751	[15,143]	[73,123]	7	hSpCas9	positive selection	2954797
43313364	43313387	1	+	27013184	SW480	treatment with recombinant TRAIL	GGCCAGCATTCAGGGGCTCGGGG	TIE1	ENSG00000066056	-0.8825537515089765	[276,502]	[64,122]	-4	hSpCas9	positive selection	2954798
43313369	43313392	1	+	27013184	SW480	treatment with recombinant TRAIL	GCATTCAGGGGCTCGGGGACTGG	TIE1	ENSG00000066056	2.0698717984148574	[210,257]	[333,544]	8	hSpCas9	positive selection	2954799
43313397	43313420	1	+	27013184	SW480	treatment with recombinant TRAIL	CACAGTAGAAGAGTCCACCCTGG	TIE1	ENSG00000066056	-1.8066894144005032	[129,197]	[4,40]	-7	hSpCas9	positive selection	2954800
43313398	43313421	1	+	27013184	SW480	treatment with recombinant TRAIL	ACAGTAGAAGAGTCCACCCTGGG	TIE1	ENSG00000066056	-0.11682611950323207	[70,84]	[17,48]	0	hSpCas9	positive selection	2954801
43307204	43307227	1	+	27013184	SW480	treatment with recombinant TRAIL	GGTGTCTGCCACGACCATGACGG	TIE1	ENSG00000066056	-1.1615300929538175	[561,503]	[66,154]	-5	hSpCas9	positive selection	2954802
43307225	43307248	1	+	27013184	SW480	treatment with recombinant TRAIL	GGCGAATGTGTATGCCCCCCTGG	TIE1	ENSG00000066056	-0.839902326995988	[844,1247]	[150,385]	-4	hSpCas9	positive selection	2954803
43307251	43307274	1	+	27013184	SW480	treatment with recombinant TRAIL	CACTGGCACCCGCTGTGAACAGG	TIE1	ENSG00000066056	-0.0701886562830401	[190,294]	[52,161]	0	hSpCas9	positive selection	2954804
43307252	43307275	1	+	27013184	SW480	treatment with recombinant TRAIL	ACTGGCACCCGCTGTGAACAGGG	TIE1	ENSG00000066056	0.7568448287612499	[372,634]	[370,341]	3	hSpCas9	positive selection	2954805
43307257	43307280	1	+	27013184	SW480	treatment with recombinant TRAIL	CACCCGCTGTGAACAGGGTAAGG	TIE1	ENSG00000066056	-1.4010392222863666	[73,40]	[14,1]	-6	hSpCas9	positive selection	2954806
43307260	43307283	1	+	27013184	SW480	treatment with recombinant TRAIL	CCGCTGTGAACAGGGTAAGGAGG	TIE1	ENSG00000066056	0.18990704980854645	[137,257]	[34,179]	1	hSpCas9	positive selection	2954807
43313271	43313294	1	+	27013184	SW480	treatment with recombinant TRAIL	AGACCCACTGTGGATAGACGTGG	TIE1	ENSG00000066056	-1.4958452292426399	[134,322]	[8,68]	-6	hSpCas9	positive selection	2954808
43313276	43313299	1	+	27013184	SW480	treatment with recombinant TRAIL	CACTGTGGATAGACGTGGACAGG	TIE1	ENSG00000066056	1.9717039609950766	[102,160]	[242,184]	8	hSpCas9	positive selection	2954809
43313274	43313297	1	-	27013184	SW480	treatment with recombinant TRAIL	TGTCCACGTCTATCCACAGTGGG	TIE1	ENSG00000066056	0.8473416520128738	[213,152]	[203,59]	4	hSpCas9	positive selection	2954810
43313275	43313298	1	-	27013184	SW480	treatment with recombinant TRAIL	CTGTCCACGTCTATCCACAGTGG	TIE1	ENSG00000066056	-0.31334893170220324	[227,238]	[37,141]	-1	hSpCas9	positive selection	2954811
43313299	43313322	1	-	27013184	SW480	treatment with recombinant TRAIL	ATGATGGTGCTTGTCTCCTCAGG	TIE1	ENSG00000066056	-0.6087278613091056	[642,932]	[220,216]	-3	hSpCas9	positive selection	2954812
43313315	43313338	1	-	27013184	SW480	treatment with recombinant TRAIL	GGCGTTGAGGCCACGGATGATGG	TIE1	ENSG00000066056	1.1385609487837307	[245,182]	[113,337]	5	hSpCas9	positive selection	2954813
43313336	43313359	1	-	27013184	SW480	treatment with recombinant TRAIL	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.25722147780734206	[612,718]	[234,491]	1	hSpCas9	positive selection	2954814
43313349	43313372	1	-	27013184	SW480	treatment with recombinant TRAIL	TGCTGGCCCGCATGCGGAAGAGG	TIE1	ENSG00000066056	-0.1258404951077885	[82,65]	[4,64]	0	hSpCas9	positive selection	2954815
43313355	43313378	1	-	27013184	SW480	treatment with recombinant TRAIL	CCTGAATGCTGGCCCGCATGCGG	TIE1	ENSG00000066056	-4.494515612606133	[69,212]	[2,1]	-9	hSpCas9	positive selection	2954816
43313366	43313389	1	-	27013184	SW480	treatment with recombinant TRAIL	GTCCCCGAGCCCCTGAATGCTGG	TIE1	ENSG00000066056	-0.09670057703563206	[152,178]	[16,136]	0	hSpCas9	positive selection	2954817
43306906	43306929	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGTGCAGCCACCATCGAGCGG	TIE1	ENSG00000066056	0.1682718471356916	[3,3]	[3,2]	3	hSpCas9	positive selection	3026774
43309097	43309120	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGAGCTACGCAAGCCAGACGG	TIE1	ENSG00000066056	0.2867706679702555	[3,3]	[3,3]	6	hSpCas9	positive selection	3026775
43305323	43305346	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACGTGATCTGGAAGAGCAACGG	TIE1	ENSG00000066056	-0.006296246078478784	[2,2]	[3,1]	0	hSpCas9	positive selection	3026776
43309045	43309068	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	0.3098874019456289	[3,3]	[4,3]	6	hSpCas9	positive selection	3026777
43306906	43306929	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGTGCAGCCACCATCGAGCGG	TIE1	ENSG00000066056	-0.2844109262350187	[3,3]	[3,0]	-4	hSpCas9	positive selection	3094632
43309097	43309120	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGAGCTACGCAAGCCAGACGG	TIE1	ENSG00000066056	-0.6293679347886868	[3,3]	[1,0]	-8	hSpCas9	positive selection	3094633
43305323	43305346	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACGTGATCTGGAAGAGCAACGG	TIE1	ENSG00000066056	0.2591395443141348	[2,2]	[1,2]	4	hSpCas9	positive selection	3094634
43309045	43309068	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-0.3210985656182693	[3,3]	[3,0]	-5	hSpCas9	positive selection	3094635
43317283	43317306		-	24336571	A375	resistance to PLX after 7 days	ATGTCCTCCCACTCTAGCACTGG	TIE1	ENSG00000066056	0.15284723169168696	[11,10]	[10,14]	5	hSpCas9	positive selection	3150273
43317356	43317379		-	24336571	A375	resistance to PLX after 7 days	CAGCCCGTCCTTCTTGATCATGG	TIE1	ENSG00000066056	-0.007917591442292204	[9,11]	[10,9]	0	hSpCas9	positive selection	3150274
43313342	43313365		+	24336571	A375	resistance to PLX after 7 days	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.18016242373410762	[23,20]	[19,18]	-5	hSpCas9	positive selection	3150275
43313275	43313298		-	24336571	A375	resistance to PLX after 7 days	CTGTCCACGTCTATCCACAGTGG	TIE1	ENSG00000066056	-0.13065561120949665	[7,4]	[5,5]	-4	hSpCas9	positive selection	3150276
43313336	43313359		-	24336571	A375	resistance to PLX after 7 days	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.13079313365762846	[9,9]	[9,8]	-4	hSpCas9	positive selection	3150277
43317332	43317355		+	24336571	A375	resistance to PLX after 7 days	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.4127262281360365	[8,8]	[10,12]	8	hSpCas9	positive selection	3150278
43317283	43317306		-	24336571	A375	resistance to PLX after 14 days	ATGTCCTCCCACTCTAGCACTGG	TIE1	ENSG00000066056	0.938701658769243	[9,13]	[8,11]	7	hSpCas9	positive selection	3208066
43317356	43317379		-	24336571	A375	resistance to PLX after 14 days	CAGCCCGTCCTTCTTGATCATGG	TIE1	ENSG00000066056	0.5379936760944048	[5,7]	[4,3]	5	hSpCas9	positive selection	3208067
43313342	43313365		+	24336571	A375	resistance to PLX after 14 days	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.5571564796543694	[20,17]	[4,6]	-6	hSpCas9	positive selection	3208068
43313275	43313298		-	24336571	A375	resistance to PLX after 14 days	CTGTCCACGTCTATCCACAGTGG	TIE1	ENSG00000066056	-0.5718025641221164	[8,6]	[1,1]	-6	hSpCas9	positive selection	3208069
43313336	43313359		-	24336571	A375	resistance to PLX after 14 days	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.30451989714129385	[11,6]	[3,2]	-3	hSpCas9	positive selection	3208070
43317332	43317355		+	24336571	A375	resistance to PLX after 14 days	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	2.1336755290426104	[7,5]	[13,14]	9	hSpCas9	positive selection	3208071
43317283	43317306		-	24336571	A375	viability after 7 days	ATGTCCTCCCACTCTAGCACTGG	TIE1	ENSG00000066056	0.4770421201785915	[8]	[11,10]	7	hSpCas9	negative selection	3265859
43317356	43317379		-	24336571	A375	viability after 7 days	CAGCCCGTCCTTCTTGATCATGG	TIE1	ENSG00000066056	0.3269024183772297	[8]	[9,11]	5	hSpCas9	negative selection	3265860
43313342	43313365		+	24336571	A375	viability after 7 days	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	0.10646348879968293	[21]	[23,20]	1	hSpCas9	negative selection	3265861
43313275	43313298		-	24336571	A375	viability after 7 days	CTGTCCACGTCTATCCACAGTGG	TIE1	ENSG00000066056	0.03903138130558881	[6]	[7,4]	0	hSpCas9	negative selection	3265862
43313336	43313359		-	24336571	A375	viability after 7 days	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	1.4977739279809708	[3]	[9,9]	9	hSpCas9	negative selection	3265863
43317332	43317355		+	24336571	A375	viability after 7 days	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.35179229303505455	[6]	[8,8]	5	hSpCas9	negative selection	3265864
43317283	43317306		-	24336571	A375	viability after 14 days	ATGTCCTCCCACTCTAGCACTGG	TIE1	ENSG00000066056	0.5526436006209823	[8]	[9,13]	7	hSpCas9	negative selection	3323652
43317356	43317379		-	24336571	A375	viability after 14 days	CAGCCCGTCCTTCTTGATCATGG	TIE1	ENSG00000066056	-0.22579997060311585	[8]	[5,7]	-3	hSpCas9	negative selection	3323653
43313342	43313365		+	24336571	A375	viability after 14 days	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.024647251232970846	[21]	[20,17]	0	hSpCas9	negative selection	3323654
43313275	43313298		-	24336571	A375	viability after 14 days	CTGTCCACGTCTATCCACAGTGG	TIE1	ENSG00000066056	0.38285667386655986	[6]	[8,6]	5	hSpCas9	negative selection	3323655
43313336	43313359		-	24336571	A375	viability after 14 days	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	1.423046369959796	[3]	[11,6]	9	hSpCas9	negative selection	3323656
43317332	43317355		+	24336571	A375	viability after 14 days	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.054509993920476285	[6]	[7,5]	0	hSpCas9	negative selection	3323657
43317318	43317341	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	7.017499196773366	[332,332]	[281,281]	9	hSpCas9	positive selection	3397172
43317332	43317355	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.5849008694743394	[101,101]	[0,0]	3	hSpCas9	positive selection	3397173
43317660	43317683	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	-0.47738340878000324	[212,212]	[0,0]	-3	hSpCas9	positive selection	3397174
43306905	43306928	1	+	26780180	HT29	viability (Avana library 4 designs)	AATGTGCAGCCACCATCGAGCGG	TIE1	ENSG00000066056	0.0818461336510876	[]	[]	0	hSpCas9	negative selection	3465515
43309096	43309119	1	+	26780180	HT29	viability (Avana library 4 designs)	ATAGAGCTACGCAAGCCAGACGG	TIE1	ENSG00000066056	0.699701084220895	[]	[]	2	hSpCas9	negative selection	3465516
43305322	43305345	1	+	26780180	HT29	viability (Avana library 4 designs)	GACGTGATCTGGAAGAGCAACGG	TIE1	ENSG00000066056	1.20511904412303	[]	[]	5	hSpCas9	negative selection	3465517
43309045	43309068	1	-	26780180	HT29	viability (Avana library 4 designs)	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	1.86183585935508	[]	[]	7	hSpCas9	negative selection	3465518
43309096	43309119	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGAGCTACGCAAGCCAGACGG	TIE1	ENSG00000066056	-3.92061183589232	[]	[]	-4	hSpCas9	negative selection	3568744
43309045	43309068	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	1.36202262015912	[]	[]	2	hSpCas9	negative selection	3568745
43306905	43306928	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATGTGCAGCCACCATCGAGCGG	TIE1	ENSG00000066056	2.37745351057358	[]	[]	3	hSpCas9	negative selection	3568746
43305322	43305345	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACGTGATCTGGAAGAGCAACGG	TIE1	ENSG00000066056	-3.75999362761	[]	[]	-4	hSpCas9	negative selection	3568747
43305158	43305181	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTGCCTAACTCACCTCCAGGG	TIE1	ENSG00000066056	2.23732450747769	[]	[]	3	hSpCas9	negative selection	3568748
43307260	43307283	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCCTTACCCTGTTCACAGCGG	TIE1	ENSG00000066056	-2.01445686127382	[]	[]	-2	hSpCas9	negative selection	3568749
43309096	43309119	1	+	26780180	A375	viability (Avana lentiGuide)	ATAGAGCTACGCAAGCCAGACGG	TIE1	ENSG00000066056	-4.45035308524065	[]	[]	-7	hSpCas9	negative selection	3677403
43309045	43309068	1	-	26780180	A375	viability (Avana lentiGuide)	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	5.56280335927076	[]	[]	5	hSpCas9	negative selection	3677404
43306905	43306928	1	+	26780180	A375	viability (Avana lentiGuide)	AATGTGCAGCCACCATCGAGCGG	TIE1	ENSG00000066056	-2.4038909811075	[]	[]	-4	hSpCas9	negative selection	3677405
43305322	43305345	1	+	26780180	A375	viability (Avana lentiGuide)	GACGTGATCTGGAAGAGCAACGG	TIE1	ENSG00000066056	4.64442498461161	[]	[]	4	hSpCas9	negative selection	3677406
43305158	43305181	1	-	26780180	A375	viability (Avana lentiGuide)	GCCTGCCTAACTCACCTCCAGGG	TIE1	ENSG00000066056	-3.80673472298906	[]	[]	-6	hSpCas9	negative selection	3677407
43307260	43307283	1	-	26780180	A375	viability (Avana lentiGuide)	CCTCCTTACCCTGTTCACAGCGG	TIE1	ENSG00000066056	-1.61729238611078	[]	[]	-3	hSpCas9	negative selection	3677408
43309096	43309119	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGAGCTACGCAAGCCAGACGG	TIE1	ENSG00000066056	-0.27111818542201727	[5]	[4,3]	-4	hSpCas9	positive selection	3786010
43309045	43309068	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	0.03797798977221006	[5]	[6,4]	0	hSpCas9	positive selection	3786011
43306905	43306928	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGTGCAGCCACCATCGAGCGG	TIE1	ENSG00000066056	0.11966957867935978	[4]	[4,5]	3	hSpCas9	positive selection	3786012
43305322	43305345	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACGTGATCTGGAAGAGCAACGG	TIE1	ENSG00000066056	0.19068153418680162	[4]	[3,6]	5	hSpCas9	positive selection	3786013
43305158	43305181	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTGCCTAACTCACCTCCAGGG	TIE1	ENSG00000066056	0.3139690309825709	[4]	[5,5]	8	hSpCas9	positive selection	3786014
43307260	43307283	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCCTTACCCTGTTCACAGCGG	TIE1	ENSG00000066056	-0.1634620007042615	[6]	[5,4]	-3	hSpCas9	positive selection	3786015
43309096	43309119	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGAGCTACGCAAGCCAGACGG	TIE1	ENSG00000066056	0.3161314455338481	[4]	[4,5]	8	hSpCas9	positive selection	3894617
43309045	43309068	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-0.28392877043827786	[6]	[5,2]	-4	hSpCas9	positive selection	3894618
43306905	43306928	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGTGCAGCCACCATCGAGCGG	TIE1	ENSG00000066056	-0.285462620603257	[5]	[4,2]	-4	hSpCas9	positive selection	3894619
43305322	43305345	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACGTGATCTGGAAGAGCAACGG	TIE1	ENSG00000066056	-0.22391182383779795	[4]	[4,1]	-3	hSpCas9	positive selection	3894620
43305158	43305181	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTGCCTAACTCACCTCCAGGG	TIE1	ENSG00000066056	0.27618243983945634	[5]	[5,4]	7	hSpCas9	positive selection	3894621
43307260	43307283	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCCTTACCCTGTTCACAGCGG	TIE1	ENSG00000066056	0.12375300085819024	[7]	[7,7]	3	hSpCas9	positive selection	3894622
43317318	43317341	1	-	26780180	A375	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	1.24627305541776	[]	[]	6	hSpCas9	negative selection	4003976
43313342	43313365	1	+	26780180	A375	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	1.1794479447248	[]	[]	6	hSpCas9	negative selection	4003977
43313336	43313359	1	-	26780180	A375	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	1.13272893850122	[]	[]	6	hSpCas9	negative selection	4003978
43317332	43317355	1	+	26780180	A375	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.990123829801166	[]	[]	4	hSpCas9	negative selection	4003979
43317660	43317683	1	-	26780180	A375	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.153030917479185	[]	[]	0	hSpCas9	negative selection	4003980
43317583	43317606	1	-	26780180	A375	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.645434678215092	[]	[]	2	hSpCas9	negative selection	4003981
43317318	43317341	1	-	26780180	HT29	viability (GeCKOv2 library)	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	0.711511072835147	[]	[]	2	hSpCas9	negative selection	4111942
43313342	43313365	1	+	26780180	HT29	viability (GeCKOv2 library)	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	0.765697921831196	[]	[]	3	hSpCas9	negative selection	4111943
43313336	43313359	1	-	26780180	HT29	viability (GeCKOv2 library)	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.958744923857824	[]	[]	4	hSpCas9	negative selection	4111944
43317332	43317355	1	+	26780180	HT29	viability (GeCKOv2 library)	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	1.6303655461099	[]	[]	8	hSpCas9	negative selection	4111945
43317660	43317683	1	-	26780180	HT29	viability (GeCKOv2 library)	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.778292455869802	[]	[]	3	hSpCas9	negative selection	4111946
43317583	43317606	1	-	26780180	HT29	viability (GeCKOv2 library)	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.894652811118697	[]	[]	4	hSpCas9	negative selection	4111947
43317283	43317306	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGTCCTCCCACTCTAGCACTGG	TIE1	ENSG00000066056	0.0049091872752902825	[3]	[1,3]	0	hSpCas9	positive selection	4176665
43317356	43317379	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGCCCGTCCTTCTTGATCATGG	TIE1	ENSG00000066056	-0.13031590763937084	[3]	[1,2]	-3	hSpCas9	positive selection	4176666
43313342	43313365	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.18848147947739569	[4]	[2,2]	-4	hSpCas9	positive selection	4176667
43313275	43313298	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGTCCACGTCTATCCACAGTGG	TIE1	ENSG00000066056	0.084950571787896	[1]	[0,0]	2	hSpCas9	positive selection	4176668
43313336	43313359	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.2211876758080551	[2]	[1,1]	5	hSpCas9	positive selection	4176669
43317332	43317355	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.40485992135795645	[3]	[1,3]	8	hSpCas9	positive selection	4176670
43317283	43317306	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGTCCTCCCACTCTAGCACTGG	TIE1	ENSG00000066056	0.19193112893647346	[2]	[0,0,3,0]	1	hSpCas9	positive selection	4240687
43317356	43317379	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGCCCGTCCTTCTTGATCATGG	TIE1	ENSG00000066056	1.5088197482638566	[1]	[3,0,0,3]	9	hSpCas9	positive selection	4240688
43313342	43313365	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	0.5535267094832473	[3]	[0,0,4,2]	4	hSpCas9	positive selection	4240689
43313275	43313298	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGTCCACGTCTATCCACAGTGG	TIE1	ENSG00000066056	0.7889960335443417	[1]	[2,3,1,0]	5	hSpCas9	positive selection	4240690
43313336	43313359	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.3172644737504666	[2]	[0,0,0,0]	-5	hSpCas9	positive selection	4240691
43317332	43317355	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.3515631147025291	[3]	[3,0,3,0]	2	hSpCas9	positive selection	4240692
43313336	43313359	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.15908873849061866	[2]	[2,2]	3	hSpCas9	positive selection	4303075
43317583	43317606	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.23543619579807762	[2]	[1,1]	5	hSpCas9	positive selection	4303076
43313342	43313365	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	0.03672931993171702	[4]	[3,2]	0	hSpCas9	positive selection	4303077
43317318	43317341	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	0.017452811167846694	[4]	[3,2]	0	hSpCas9	positive selection	4367328
43317332	43317355	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.0593060705825062	[2]	[1,1]	-1	hSpCas9	positive selection	4367329
43317660	43317683	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.3483655247347802	[3]	[3,2]	7	hSpCas9	positive selection	4367330
43304995	43305017	1	+	27760321	OCIAML3	viability	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	-0.04734089332678737	[1009,916]	[716,743]	0	hSpCas9	negative selection	4446944
43305050	43305072	1	-	27760321	OCIAML3	viability	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	0.3404438448479803	[285,202]	[219,264]	4	hSpCas9	negative selection	4446945
43312010	43312032	1	+	27760321	OCIAML3	viability	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	0.6044330458397967	[338,292]	[316,449]	7	hSpCas9	negative selection	4446946
43306917	43306939	1	-	27760321	OCIAML3	viability	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	-0.2769351466574417	[860,762]	[468,593]	-3	hSpCas9	negative selection	4446947
43306972	43306994	1	-	27760321	OCIAML3	viability	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	-0.10817471620987507	[392,299]	[245,253]	-1	hSpCas9	negative selection	4446948
43304995	43305017	1	+	27760321	OCIAML2	viability	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	0.23401966953814535	[1009,916]	[758,1122]	3	hSpCas9	negative selection	4530407
43305050	43305072	1	-	27760321	OCIAML2	viability	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	0.3722111679145373	[285,202]	[232,279]	5	hSpCas9	negative selection	4530408
43312010	43312032	1	+	27760321	OCIAML2	viability	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	-0.5884209062011372	[338,292]	[150,193]	-6	hSpCas9	negative selection	4530409
43306917	43306939	1	-	27760321	OCIAML2	viability	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	-0.2774309951219266	[860,762]	[490,606]	-3	hSpCas9	negative selection	4530410
43306972	43306994	1	-	27760321	OCIAML2	viability	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	0.6096165247456021	[392,299]	[407,445]	8	hSpCas9	negative selection	4530411
43304995	43305017	1	+	27760321	MV411	viability	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	0.03707866750521571	[1009,916]	[561,786]	0	hSpCas9	negative selection	4613870
43305050	43305072	1	-	27760321	MV411	viability	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	-2.2407056963048775	[285,202]	[2,79]	-8	hSpCas9	negative selection	4613871
43312010	43312032	1	+	27760321	MV411	viability	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	0.8235353451629632	[338,292]	[184,642]	6	hSpCas9	negative selection	4613872
43306917	43306939	1	-	27760321	MV411	viability	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	0.32009575285034186	[860,762]	[706,608]	2	hSpCas9	negative selection	4613873
43306972	43306994	1	-	27760321	MV411	viability	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	0.3729095860929639	[392,299]	[65,635]	2	hSpCas9	negative selection	4613874
43304995	43305017	1	+	27760321	HL60	viability	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	-0.0572558168213666	[1009,916]	[769,740]	0	hSpCas9	negative selection	4697333
43305050	43305072	1	-	27760321	HL60	viability	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	0.2126352831280911	[285,202]	[161,299]	2	hSpCas9	negative selection	4697334
43312010	43312032	1	+	27760321	HL60	viability	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	-1.399053423173002	[338,292]	[117,75]	-8	hSpCas9	negative selection	4697335
43306917	43306939	1	-	27760321	HL60	viability	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	0.09223644945326148	[860,762]	[669,743]	1	hSpCas9	negative selection	4697336
43306972	43306994	1	-	27760321	HL60	viability	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	-0.08467662711641627	[392,299]	[292,234]	-1	hSpCas9	negative selection	4697337
43304995	43305017	1	+	27760321	HT1080	viability	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	1.1208027792570558	[916,715]	[493,940]	6	hSpCas9	negative selection	4780796
43305050	43305072	1	-	27760321	HT1080	viability	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	-1.952470426813787	[202,158]	[31,3]	-6	hSpCas9	negative selection	4780797
43312010	43312032	1	+	27760321	HT1080	viability	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	0.9213769947282244	[292,228]	[163,232]	5	hSpCas9	negative selection	4780798
43306917	43306939	1	-	27760321	HT1080	viability	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	-3.7406765194544827	[762,595]	[14,25]	-8	hSpCas9	negative selection	4780799
43306972	43306994	1	-	27760321	HT1080	viability	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	1.6366005287342593	[299,233]	[292,371]	8	hSpCas9	negative selection	4780800
43304995	43305017	1	+	27760321	HT29	viability after 7 days	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	-0.12483978272188656	[916,715]	[1131,844,934]	-2	hSpCas9	negative selection	4864259
43305050	43305072	1	-	27760321	HT29	viability after 7 days	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	0.39462715029800133	[202,158]	[190,494,217]	6	hSpCas9	negative selection	4864260
43312010	43312032	1	+	27760321	HT29	viability after 7 days	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	0.08032963828080197	[292,228]	[719,199,200]	1	hSpCas9	negative selection	4864261
43306917	43306939	1	-	27760321	HT29	viability after 7 days	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	-0.4292772339040306	[762,595]	[747,540,669]	-6	hSpCas9	negative selection	4864262
43306972	43306994	1	-	27760321	HT29	viability after 7 days	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	0.31096995729588156	[299,233]	[407,396,467]	5	hSpCas9	negative selection	4864263
43304995	43305017	1	+	27760321	HT29	viability after 25 days	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	0.20357584026331388	[916,715]	[961,1210,1053]	2	hSpCas9	negative selection	4947722
43305050	43305072	1	-	27760321	HT29	viability after 25 days	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	0.23713480008814414	[202,158]	[284,273,160]	2	hSpCas9	negative selection	4947723
43312010	43312032	1	+	27760321	HT29	viability after 25 days	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	0.126862231140423	[292,228]	[250,338,398]	1	hSpCas9	negative selection	4947724
43306917	43306939	1	-	27760321	HT29	viability after 25 days	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	0.20782121024709366	[762,595]	[951,663,1089]	2	hSpCas9	negative selection	4947725
43306972	43306994	1	-	27760321	HT29	viability after 25 days	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	0.2819368357542066	[299,233]	[299,409,410]	3	hSpCas9	negative selection	4947726
43304995	43305017	1	+	27760321	HT29	viability after 22 days	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	0.42597788228951305	[916,715]	[1204,1244,1356]	4	hSpCas9	negative selection	5031185
43305050	43305072	1	-	27760321	HT29	viability after 22 days	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	-0.07051626264596489	[202,158]	[235,257,101]	0	hSpCas9	negative selection	5031186
43312010	43312032	1	+	27760321	HT29	viability after 22 days	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	-0.04503387235849693	[292,228]	[257,365,253]	0	hSpCas9	negative selection	5031187
43306917	43306939	1	-	27760321	HT29	viability after 22 days	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	0.01100940666103678	[762,595]	[982,550,835]	0	hSpCas9	negative selection	5031188
43306972	43306994	1	-	27760321	HT29	viability after 22 days	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	1.0391291153558142	[299,233]	[715,508,675]	9	hSpCas9	negative selection	5031189
43304995	43305017	1	+	27760321	HT29	viability after 19 days	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	-0.21597003518729352	[916,715]	[806,779,823]	-2	hSpCas9	negative selection	5114648
43305050	43305072	1	-	27760321	HT29	viability after 19 days	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	0.3457135687457106	[202,158]	[296,400,100]	3	hSpCas9	negative selection	5114649
43312010	43312032	1	+	27760321	HT29	viability after 19 days	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	-0.43414180708209965	[292,228]	[138,290,223]	-4	hSpCas9	negative selection	5114650
43306917	43306939	1	-	27760321	HT29	viability after 19 days	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	-0.02782276722856447	[762,595]	[948,433,916]	0	hSpCas9	negative selection	5114651
43306972	43306994	1	-	27760321	HT29	viability after 19 days	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	0.7181055988187195	[299,233]	[417,717,366]	7	hSpCas9	negative selection	5114652
43304995	43305017	1	+	27760321	HT29	viability after 16 days	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	0.015526128341926793	[916,715]	[854,755,1156]	0	hSpCas9	negative selection	5198111
43305050	43305072	1	-	27760321	HT29	viability after 16 days	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	0.07475308788470925	[202,158]	[381,207,65]	0	hSpCas9	negative selection	5198112
43312010	43312032	1	+	27760321	HT29	viability after 16 days	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	0.20133688713843972	[292,228]	[326,466,208]	2	hSpCas9	negative selection	5198113
43306917	43306939	1	-	27760321	HT29	viability after 16 days	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	0.020319556807407047	[762,595]	[1042,453,849]	0	hSpCas9	negative selection	5198114
43306972	43306994	1	-	27760321	HT29	viability after 16 days	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	0.7235003196404297	[299,233]	[508,304,671]	8	hSpCas9	negative selection	5198115
43304995	43305017	1	+	27760321	HT29	viability after 13 days	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	-0.05969818309566355	[916,715]	[1004,1030,702]	0	hSpCas9	negative selection	5281574
43305050	43305072	1	-	27760321	HT29	viability after 13 days	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	0.3604024488723512	[202,158]	[243,245,315]	4	hSpCas9	negative selection	5281575
43312010	43312032	1	+	27760321	HT29	viability after 13 days	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	-0.21274377795202098	[292,228]	[248,360,178]	-3	hSpCas9	negative selection	5281576
43306917	43306939	1	-	27760321	HT29	viability after 13 days	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	0.03758890466509346	[762,595]	[1074,769,594]	0	hSpCas9	negative selection	5281577
43306972	43306994	1	-	27760321	HT29	viability after 13 days	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	0.5285463287069375	[299,233]	[376,457,501]	6	hSpCas9	negative selection	5281578
43304995	43305017	1	+	27760321	HT29	viability after 10 days	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	0.3806627183345299	[916,715]	[969,1493,1517]	5	hSpCas9	negative selection	5365037
43305050	43305072	1	-	27760321	HT29	viability after 10 days	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	0.14854365638902278	[202,158]	[293,318,142]	2	hSpCas9	negative selection	5365038
43312010	43312032	1	+	27760321	HT29	viability after 10 days	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	0.29946427357564176	[292,228]	[582,295,322]	4	hSpCas9	negative selection	5365039
43306917	43306939	1	-	27760321	HT29	viability after 10 days	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	0.22308879499917544	[762,595]	[1171,912,885]	3	hSpCas9	negative selection	5365040
43306972	43306994	1	-	27760321	HT29	viability after 10 days	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	0.5847784475760235	[299,233]	[673,465,361]	7	hSpCas9	negative selection	5365041
43304995	43305017	1	+	27760321	MOLM13	viability	GTATCGTGCGCACCCCGCCCGG	TIE1	ENSG00000066056	0.9283379554008893	[1009,916]	[1042,1025]	6	hSpCas9	negative selection	5448500
43305050	43305072	1	-	27760321	MOLM13	viability	GAAGCCGCGAAGCGTGACCTGG	TIE1	ENSG00000066056	-0.8737301136751944	[285,202]	[141,16]	-5	hSpCas9	negative selection	5448501
43312010	43312032	1	+	27760321	MOLM13	viability	CGTGACGTTAATGAACCTGAGG	TIE1	ENSG00000066056	0.7889835794291803	[338,292]	[162,429]	5	hSpCas9	negative selection	5448502
43306917	43306939	1	-	27760321	MOLM13	viability	CACTGTAGATGCCGCTCGATGG	TIE1	ENSG00000066056	-0.5446095859095268	[860,762]	[258,359]	-3	hSpCas9	negative selection	5448503
43306972	43306994	1	-	27760321	MOLM13	viability	CGCACGATGAGCCGAAAGAAGG	TIE1	ENSG00000066056	-0.6892947324015966	[392,299]	[122,117]	-4	hSpCas9	negative selection	5448504
43301010	43301033	1	+	27661255	K562	viability	GGCCCACAGCATCTGACCCCAGG	TIE1	ENSG00000066056	-0.07116998627651433	[969,1126]	[881,720]	-3	dCas9-KRAB	negative selection	5517289
43301012	43301035	1	-	27661255	K562	viability	GGCCTGGGGTCAGATGCTGTGGG	TIE1	ENSG00000066056	0.21525102546244157	[649,759]	[679,627]	7	dCas9-KRAB	negative selection	5517290
43301447	43301470	1	-	27661255	K562	viability	GTCTAAACACAATGGAGACGGGG	TIE1	ENSG00000066056	0.4142066161628768	[129,117]	[135,128]	9	dCas9-KRAB	negative selection	5517291
43313336	43313359	1	-	27260156	BXPC3	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.16505634874938516	[406]	[425,261,365,474]	-4	hSpCas9	negative selection	5575535
43317583	43317606	1	-	27260156	BXPC3	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.1302140820792066	[206]	[176,139,214,272]	-3	hSpCas9	negative selection	5575536
43313342	43313365	1	+	27260156	BXPC3	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.27891491691688186	[1010]	[844,954,790,885]	-6	hSpCas9	negative selection	5575537
43317318	43317341	1	-	27260156	BXPC3	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.3956295775936669	[1287]	[1018,894,1070,1123]	-7	hSpCas9	negative selection	5639788
43317332	43317355	1	+	27260156	BXPC3	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.19125329700694038	[271]	[277,200,196,326]	-4	hSpCas9	negative selection	5639789
43317660	43317683	1	-	27260156	BXPC3	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.29916255556867655	[517]	[614,653,678,726]	6	hSpCas9	negative selection	5639790
43313336	43313359	1	-	27260156	A673	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.10475285602083864	[406]	[518,362,467,477]	-3	hSpCas9	negative selection	5696786
43317583	43317606	1	-	27260156	A673	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.17049124185616438	[206]	[296,265,273,283]	4	hSpCas9	negative selection	5696787
43313342	43313365	1	+	27260156	A673	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.16739177481566003	[1010]	[1365,912,921,1163]	-4	hSpCas9	negative selection	5696788
43317318	43317341	1	-	27260156	A673	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.030100261729997246	[1287]	[1757,1511,1453,1350]	0	hSpCas9	negative selection	5761039
43317332	43317355	1	+	27260156	A673	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.0010477098001259177	[271]	[396,338,268,308]	0	hSpCas9	negative selection	5761040
43317660	43317683	1	-	27260156	A673	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.24457803805327782	[517]	[828,730,653,743]	6	hSpCas9	negative selection	5761041
43313336	43313359	1	-	27260156	A375	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.131444417651851	[406]	[706,501,482,401]	2	hSpCas9	negative selection	5818037
43317583	43317606	1	-	27260156	A375	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.6039821909272587	[206]	[292,332,486,351]	8	hSpCas9	negative selection	5818038
43313342	43313365	1	+	27260156	A375	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.5399053814303562	[1010]	[804,1039,700,739]	-6	hSpCas9	negative selection	5818039
43317318	43317341	1	-	27260156	A375	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.41978461144446055	[1287]	[1251,1305,1104,885]	-5	hSpCas9	negative selection	5882290
43317332	43317355	1	+	27260156	A375	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.21155868322086224	[271]	[241,281,490,102]	-3	hSpCas9	negative selection	5882291
43317660	43317683	1	-	27260156	A375	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.6086514995283875	[517]	[764,1241,856,871]	8	hSpCas9	negative selection	5882292
43313336	43313359	1	-	27260156	COLO741	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.5739788472029855	[406]	[372,407,273]	-8	hSpCas9	negative selection	5939288
43317583	43317606	1	-	27260156	COLO741	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.01728194989028764	[206]	[346,202,241]	0	hSpCas9	negative selection	5939289
43313342	43313365	1	+	27260156	COLO741	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.35122149554798787	[1010]	[1094,1039,914]	-6	hSpCas9	negative selection	5939290
43317318	43317341	1	-	27260156	COLO741	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.4034705663452036	[1287]	[1338,1437,980]	-7	hSpCas9	negative selection	6003541
43317332	43317355	1	+	27260156	COLO741	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.09941956053244239	[271]	[359,366,386]	2	hSpCas9	negative selection	6003542
43317660	43317683	1	-	27260156	COLO741	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.36656497229372065	[517]	[798,865,885]	7	hSpCas9	negative selection	6003543
43313336	43313359	1	-	27260156	CAL120	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.4358290997844193	[406]	[257,552,295]	-6	hSpCas9	negative selection	6060539
43317583	43317606	1	-	27260156	CAL120	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.32106821986307543	[206]	[271,183,172]	-5	hSpCas9	negative selection	6060540
43313342	43313365	1	+	27260156	CAL120	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.44997061385431814	[1010]	[971,1198,604]	-6	hSpCas9	negative selection	6060541
43317318	43317341	1	-	27260156	CAL120	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.5061461669439378	[1287]	[1131,1091,1160]	-6	hSpCas9	negative selection	6124792
43317332	43317355	1	+	27260156	CAL120	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.20904049143441905	[271]	[407,482,286]	3	hSpCas9	negative selection	6124793
43317660	43317683	1	-	27260156	CAL120	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.3737445655799707	[517]	[1216,805,544]	5	hSpCas9	negative selection	6124794
43313336	43313359	1	-	27260156	CADOES1	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.03976315304987993	[406]	[251,335,493,477]	0	hSpCas9	negative selection	6181790
43317583	43317606	1	-	27260156	CADOES1	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.14503528119083042	[206]	[304,212,153,177]	2	hSpCas9	negative selection	6181791
43313342	43313365	1	+	27260156	CADOES1	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.11962461324386187	[1010]	[869,1007,697,886]	-2	hSpCas9	negative selection	6181792
43317318	43317341	1	-	27260156	CADOES1	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.3706967513429924	[1287]	[991,1188,760,757]	-6	hSpCas9	negative selection	6246043
43317332	43317355	1	+	27260156	CADOES1	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.44109991166054413	[271]	[280,246,647,191]	7	hSpCas9	negative selection	6246044
43317660	43317683	1	-	27260156	CADOES1	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.42040891523154145	[517]	[562,519,670,831]	7	hSpCas9	negative selection	6246045
43313336	43313359	1	-	27260156	EWS502	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.21860351161738292	[406]	[341,304,469,370]	-4	hSpCas9	negative selection	6303041
43317583	43317606	1	-	27260156	EWS502	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.03410865829605525	[206]	[388,153,117,216]	0	hSpCas9	negative selection	6303042
43313342	43313365	1	+	27260156	EWS502	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.3817656369897001	[1010]	[802,833,828,819]	-6	hSpCas9	negative selection	6303043
43317318	43317341	1	-	27260156	EWS502	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.32875989027837593	[1287]	[970,981,1341,1065]	-5	hSpCas9	negative selection	6367294
43317332	43317355	1	+	27260156	EWS502	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.10761688358698629	[271]	[367,266,239,362]	1	hSpCas9	negative selection	6367295
43317660	43317683	1	-	27260156	EWS502	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.48618441503243415	[517]	[628,901,827,720]	8	hSpCas9	negative selection	6367296
43313336	43313359	1	-	27260156	EW8	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.11777108460907473	[406]	[390,342,220,283]	-2	hSpCas9	negative selection	6424292
43317583	43317606	1	-	27260156	EW8	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.6205754609287342	[206]	[401,146,223,278]	9	hSpCas9	negative selection	6424293
43313342	43313365	1	+	27260156	EW8	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.23652406257561487	[1010]	[792,763,540,718]	-4	hSpCas9	negative selection	6424294
43317318	43317341	1	-	27260156	EW8	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.3540884606614636	[1287]	[1222,729,668,711]	-6	hSpCas9	negative selection	6488545
43317332	43317355	1	+	27260156	EW8	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.34203055257778037	[271]	[319,240,285,272]	6	hSpCas9	negative selection	6488546
43317660	43317683	1	-	27260156	EW8	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.36039608167735615	[517]	[636,450,475,610]	6	hSpCas9	negative selection	6488547
43313336	43313359	1	-	27260156	CORL105	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.023724691492853445	[406]	[438,442,531,469]	0	hSpCas9	negative selection	6545543
43317583	43317606	1	-	27260156	CORL105	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.323671640311305	[206]	[369,254,244,336]	6	hSpCas9	negative selection	6545544
43313342	43313365	1	+	27260156	CORL105	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.14901010511384938	[1010]	[1051,1065,1312,876]	-3	hSpCas9	negative selection	6545545
43317318	43317341	1	-	27260156	CORL105	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.09258342454938329	[1287]	[1368,1379,1596,1337]	-2	hSpCas9	negative selection	6609796
43317332	43317355	1	+	27260156	CORL105	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.3261772094703032	[271]	[385,402,460,355]	6	hSpCas9	negative selection	6609797
43317660	43317683	1	-	27260156	CORL105	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.37167556863180107	[517]	[820,679,795,845]	7	hSpCas9	negative selection	6609798
43313336	43313359	1	-	27260156	HS294T	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.15966353944043934	[406]	[107,201,98,157]	-2	hSpCas9	negative selection	6666794
43317583	43317606	1	-	27260156	HS294T	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.6290276901882204	[206]	[216,64,74,131]	7	hSpCas9	negative selection	6666795
43313342	43313365	1	+	27260156	HS294T	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.41388843078493354	[1010]	[409,202,244,308]	-5	hSpCas9	negative selection	6666796
43317318	43317341	1	-	27260156	HS294T	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.6826246664616014	[1287]	[276,273,270,444]	-7	hSpCas9	negative selection	6731047
43317332	43317355	1	+	27260156	HS294T	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.41334364988782224	[271]	[51,61,69,145]	-5	hSpCas9	negative selection	6731048
43317660	43317683	1	-	27260156	HS294T	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.1289610322462758	[517]	[190,287,190,202]	1	hSpCas9	negative selection	6731049
43313336	43313359	1	-	27260156	HCC44	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.36441012086057045	[406]	[422,292,386,344]	-5	hSpCas9	negative selection	6788045
43317583	43317606	1	-	27260156	HCC44	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.31407684279121506	[206]	[268,110,204,187]	-5	hSpCas9	negative selection	6788046
43313342	43313365	1	+	27260156	HCC44	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.5404551845499296	[1010]	[753,743,986,693]	-7	hSpCas9	negative selection	6788047
43317318	43317341	1	-	27260156	HCC44	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.9960037946649963	[1287]	[1005,517,968,525]	-8	hSpCas9	negative selection	6852298
43317332	43317355	1	+	27260156	HCC44	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.05587194511058302	[271]	[583,127,315,299]	0	hSpCas9	negative selection	6852299
43317660	43317683	1	-	27260156	HCC44	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.2876575208802354	[517]	[783,519,881,730]	5	hSpCas9	negative selection	6852300
43313336	43313359	1	-	27260156	G402	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.2855526431011579	[406]	[586,343,671,788]	3	hSpCas9	negative selection	6909296
43317583	43317606	1	-	27260156	G402	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.10790506195633309	[206]	[348,182,52,358]	-1	hSpCas9	negative selection	6909297
43313342	43313365	1	+	27260156	G402	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.4474470862114974	[1010]	[750,898,1045,896]	-5	hSpCas9	negative selection	6909298
43317318	43317341	1	-	27260156	G402	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.4479021066185511	[1287]	[1274,1173,805,1357]	-5	hSpCas9	negative selection	6973549
43317332	43317355	1	+	27260156	G402	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.25048691237874987	[271]	[379,322,233,198]	-3	hSpCas9	negative selection	6973550
43317660	43317683	1	-	27260156	G402	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.7377578506613613	[517]	[1212,1359,779,906]	8	hSpCas9	negative selection	6973551
43313336	43313359	1	-	27260156	L33	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.2255558138101074	[406]	[405,148,182,329]	-5	hSpCas9	negative selection	7030547
43317583	43317606	1	-	27260156	L33	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.0017985900990096226	[206]	[220,85,115,210]	0	hSpCas9	negative selection	7030548
43313342	43313365	1	+	27260156	L33	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.28651924682104035	[1010]	[832,330,549,799]	-6	hSpCas9	negative selection	7030549
43317318	43317341	1	-	27260156	L33	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.141012517828206	[1287]	[1298,468,711,1092]	-3	hSpCas9	negative selection	7094800
43317332	43317355	1	+	27260156	L33	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.040953326043216776	[271]	[237,152,188,208]	0	hSpCas9	negative selection	7094801
43317660	43317683	1	-	27260156	L33	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	-0.04255469115707888	[517]	[546,212,302,461]	-1	hSpCas9	negative selection	7094802
43313336	43313359	1	-	27260156	K562	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.15131743759173052	[406]	[413,654,352,216]	1	hSpCas9	negative selection	7151798
43317583	43317606	1	-	27260156	K562	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.24460922375135752	[206]	[177,68,196,170]	-3	hSpCas9	negative selection	7151799
43313342	43313365	1	+	27260156	K562	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.19235399003643572	[1010]	[448,913,1112,655]	-2	hSpCas9	negative selection	7151800
43317318	43317341	1	-	27260156	K562	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.6938832825682422	[1287]	[840,378,360,1179]	-7	hSpCas9	negative selection	7216051
43317332	43317355	1	+	27260156	K562	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.1607264028262978	[271]	[393,291,213,197]	2	hSpCas9	negative selection	7216052
43317660	43317683	1	-	27260156	K562	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.707740876738095	[517]	[754,989,480,782]	8	hSpCas9	negative selection	7216053
43313336	43313359	1	-	27260156	HT29	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.09454500181864964	[406]	[505,355,615,376]	-2	hSpCas9	negative selection	7273049
43317583	43317606	1	-	27260156	HT29	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.17969426297090352	[206]	[232,219,368,303]	3	hSpCas9	negative selection	7273050
43313342	43313365	1	+	27260156	HT29	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.2612542036040856	[1010]	[1041,1217,790,1056]	-5	hSpCas9	negative selection	7273051
43317318	43317341	1	-	27260156	HT29	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.1732049823704105	[1287]	[1516,1419,1403,1234]	-4	hSpCas9	negative selection	7337302
43317332	43317355	1	+	27260156	HT29	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.07914438867924845	[271]	[253,367,297,327]	-2	hSpCas9	negative selection	7337303
43317660	43317683	1	-	27260156	HT29	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.42976655740137437	[517]	[890,919,879,720]	8	hSpCas9	negative selection	7337304
43313336	43313359	1	-	27260156	MHHES1	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.22225228978841546	[406]	[344,524,424,297]	-4	hSpCas9	negative selection	7394300
43317583	43317606	1	-	27260156	MHHES1	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.33987878335689703	[206]	[170,211,132,210]	-6	hSpCas9	negative selection	7394301
43313342	43313365	1	+	27260156	MHHES1	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.2995361574524511	[1010]	[1030,1147,1086,540]	-5	hSpCas9	negative selection	7394302
43317318	43317341	1	-	27260156	MHHES1	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.38015670601012785	[1287]	[1301,1212,994,984]	-6	hSpCas9	negative selection	7458553
43317332	43317355	1	+	27260156	MHHES1	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.32718564448733223	[271]	[264,296,245,184]	-6	hSpCas9	negative selection	7458554
43317660	43317683	1	-	27260156	MHHES1	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.3204970730454943	[517]	[853,831,646,615]	6	hSpCas9	negative selection	7458555
43313336	43313359	1	-	27260156	MEWO	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.04832437519449026	[406]	[339,396,361]	-1	hSpCas9	negative selection	7515551
43317583	43317606	1	-	27260156	MEWO	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.2757191289757184	[206]	[329,192,198]	6	hSpCas9	negative selection	7515552
43313342	43313365	1	+	27260156	MEWO	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.39139964954553275	[1010]	[1064,677,486]	-7	hSpCas9	negative selection	7515553
43317318	43317341	1	-	27260156	MEWO	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	0.13753366382062415	[1287]	[1447,1330,1220]	3	hSpCas9	negative selection	7579804
43317332	43317355	1	+	27260156	MEWO	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.1107487480413274	[271]	[163,249,278]	-2	hSpCas9	negative selection	7579805
43317660	43317683	1	-	27260156	MEWO	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.4856392224548728	[517]	[614,727,679]	8	hSpCas9	negative selection	7579806
43313336	43313359	1	-	27260156	LNCAPCLONEFGC	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.2761341520136964	[406]	[232,338,312,332]	-4	hSpCas9	negative selection	7636802
43317583	43317606	1	-	27260156	LNCAPCLONEFGC	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.2681371012773548	[206]	[311,208,228,152]	4	hSpCas9	negative selection	7636803
43313342	43313365	1	+	27260156	LNCAPCLONEFGC	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.4482108697613587	[1010]	[752,605,783,560]	-6	hSpCas9	negative selection	7636804
43317318	43317341	1	-	27260156	LNCAPCLONEFGC	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.4897011821737026	[1287]	[793,705,991,863]	-6	hSpCas9	negative selection	7701055
43317332	43317355	1	+	27260156	LNCAPCLONEFGC	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.10095614329413127	[271]	[359,276,222,187]	1	hSpCas9	negative selection	7701056
43317660	43317683	1	-	27260156	LNCAPCLONEFGC	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.2554825985811078	[517]	[629,459,664,505]	4	hSpCas9	negative selection	7701057
43313336	43313359	1	-	27260156	PANC0327	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.08899150382148077	[406]	[316,199,501,356]	-1	hSpCas9	negative selection	7758053
43317583	43317606	1	-	27260156	PANC0327	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.49953074440839307	[206]	[288,231,364,159]	7	hSpCas9	negative selection	7758054
43313342	43313365	1	+	27260156	PANC0327	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.5485961557572651	[1010]	[560,608,574,706]	-7	hSpCas9	negative selection	7758055
43317318	43317341	1	-	27260156	PANC0327	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.4357246584688037	[1287]	[598,740,1113,922]	-6	hSpCas9	negative selection	7822306
43317332	43317355	1	+	27260156	PANC0327	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.09492685727874861	[271]	[228,156,234,292]	-1	hSpCas9	negative selection	7822307
43317660	43317683	1	-	27260156	PANC0327	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.6139668107145134	[517]	[1011,445,584,831]	8	hSpCas9	negative selection	7822308
43313336	43313359	1	-	27260156	NCIH2009	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.6057565631468925	[406]	[1167,831,654]	8	hSpCas9	negative selection	7879304
43317583	43317606	1	-	27260156	NCIH2009	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.37465393003007685	[206]	[353,271,495]	5	hSpCas9	negative selection	7879305
43313342	43313365	1	+	27260156	NCIH2009	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.015394921950600882	[1010]	[1590,1312,1325]	0	hSpCas9	negative selection	7879306
43317318	43317341	1	-	27260156	NCIH2009	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	0.5232914950001464	[1287]	[3072,2467,2311]	7	hSpCas9	negative selection	7943557
43317332	43317355	1	+	27260156	NCIH2009	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.0319748339974566	[271]	[464,337,377]	0	hSpCas9	negative selection	7943558
43317660	43317683	1	-	27260156	NCIH2009	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.5650684814247369	[517]	[1286,855,1113]	7	hSpCas9	negative selection	7943559
43313336	43313359	1	-	27260156	NCIH1373	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.3542932992582838	[406]	[536,329,125,124]	-4	hSpCas9	negative selection	8000555
43317583	43317606	1	-	27260156	NCIH1373	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.05278990302851483	[206]	[91,109,495,46]	0	hSpCas9	negative selection	8000556
43313342	43313365	1	+	27260156	NCIH1373	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.8731697330650136	[1010]	[582,490,718,180]	-7	hSpCas9	negative selection	8000557
43317318	43317341	1	-	27260156	NCIH1373	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.9970001854990687	[1287]	[765,738,642,196]	-7	hSpCas9	negative selection	8064808
43317332	43317355	1	+	27260156	NCIH1373	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.425974685416852	[271]	[540,120,107,51]	-4	hSpCas9	negative selection	8064809
43317660	43317683	1	-	27260156	NCIH1373	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.39904351290812234	[517]	[1108,661,569,206]	4	hSpCas9	negative selection	8064810
43313336	43313359	1	-	27260156	PATU8902	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.32995694751888704	[406]	[422,363,423,615]	-3	hSpCas9	negative selection	8121806
43317583	43317606	1	-	27260156	PATU8902	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.22560686341489444	[206]	[216,415,118,268]	-2	hSpCas9	negative selection	8121807
43313342	43313365	1	+	27260156	PATU8902	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.49231172976034254	[1010]	[1023,795,1077,1086]	-5	hSpCas9	negative selection	8121808
43317318	43317341	1	-	27260156	PATU8902	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.7909470023533666	[1287]	[749,1204,979,1247]	-6	hSpCas9	negative selection	8186059
43317332	43317355	1	+	27260156	PATU8902	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.2873237010254128	[271]	[228,223,408,357]	-3	hSpCas9	negative selection	8186060
43317660	43317683	1	-	27260156	PATU8902	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.7545954464560533	[517]	[1731,681,1011,1512]	7	hSpCas9	negative selection	8186061
43313336	43313359	1	-	27260156	PANC1	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.014009370161011642	[406]	[396,412,487,153]	0	hSpCas9	negative selection	8243057
43317583	43317606	1	-	27260156	PANC1	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.07416238887966609	[206]	[131,323,101,149]	-1	hSpCas9	negative selection	8243058
43313342	43313365	1	+	27260156	PANC1	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.6322576083966569	[1010]	[555,897,431,434]	-7	hSpCas9	negative selection	8243059
43317318	43317341	1	-	27260156	PANC1	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.898443196471054	[1287]	[462,644,563,688]	-8	hSpCas9	negative selection	8307310
43317332	43317355	1	+	27260156	PANC1	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.0676691443883658	[271]	[220,296,163,220]	-1	hSpCas9	negative selection	8307311
43317660	43317683	1	-	27260156	PANC1	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.3460778776118264	[517]	[505,612,679,479]	5	hSpCas9	negative selection	8307312
43313336	43313359	1	-	27260156	PANC0813	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.19327701210100537	[406]	[544,323,352,458]	-3	hSpCas9	negative selection	8364308
43317583	43317606	1	-	27260156	PANC0813	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.5151756954593493	[206]	[373,231,534,256]	7	hSpCas9	negative selection	8364309
43313342	43313365	1	+	27260156	PANC0813	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.46050286743778235	[1010]	[1273,698,740,778]	-6	hSpCas9	negative selection	8364310
43317318	43317341	1	-	27260156	PANC0813	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.3079620180537028	[1287]	[1926,1041,1092,906]	-5	hSpCas9	negative selection	8428561
43317332	43317355	1	+	27260156	PANC0813	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.03854448276013067	[271]	[346,158,296,436]	0	hSpCas9	negative selection	8428562
43317660	43317683	1	-	27260156	PANC0813	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.17478970982261383	[517]	[732,945,608,473]	3	hSpCas9	negative selection	8428563
43313336	43313359	1	-	27260156	RDES	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.06939071419527124	[406]	[343,384,428,675]	-1	hSpCas9	negative selection	8485559
43317583	43317606	1	-	27260156	RDES	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.3062319847392665	[206]	[192,125,185,277]	-5	hSpCas9	negative selection	8485560
43313342	43313365	1	+	27260156	RDES	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.5420684882487956	[1010]	[652,679,895,1021]	-7	hSpCas9	negative selection	8485561
43317318	43317341	1	-	27260156	RDES	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.6188615173298675	[1287]	[646,1221,987,1026]	-8	hSpCas9	negative selection	8549812
43317332	43317355	1	+	27260156	RDES	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.13495554315327363	[271]	[292,309,432,344]	2	hSpCas9	negative selection	8549813
43317660	43317683	1	-	27260156	RDES	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.579472216070523	[517]	[707,855,1069,959]	8	hSpCas9	negative selection	8549814
43313336	43313359	1	-	27260156	PC3	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.32733967631881133	[406]	[277,432,963,604]	7	hSpCas9	negative selection	8606810
43317583	43317606	1	-	27260156	PC3	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.0360871937046876	[206]	[184,166,356,178]	0	hSpCas9	negative selection	8606811
43313342	43313365	1	+	27260156	PC3	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.028474511445121475	[1010]	[572,906,1971,980]	0	hSpCas9	negative selection	8606812
43317318	43317341	1	-	27260156	PC3	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	0.016918059995363333	[1287]	[1084,1259,1551,1328]	0	hSpCas9	negative selection	8671063
43317332	43317355	1	+	27260156	PC3	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.06426453829916945	[271]	[244,225,263,275]	-1	hSpCas9	negative selection	8671064
43317660	43317683	1	-	27260156	PC3	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.09362369581560129	[517]	[343,636,876,501]	2	hSpCas9	negative selection	8671065
43313336	43313359	1	-	27260156	PATU8988T	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.2973944766831183	[406]	[354,540,406,649]	5	hSpCas9	negative selection	8728061
43317583	43317606	1	-	27260156	PATU8988T	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	-0.15138042585631295	[206]	[207,141,173,193]	-3	hSpCas9	negative selection	8728062
43313342	43313365	1	+	27260156	PATU8988T	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	0.18521486489060646	[1010]	[1132,824,628,1898]	3	hSpCas9	negative selection	8728063
43317318	43317341	1	-	27260156	PATU8988T	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.5176394918237793	[1287]	[802,762,1069,824]	-7	hSpCas9	negative selection	8792314
43317332	43317355	1	+	27260156	PATU8988T	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.08003450283703395	[271]	[252,231,333,287]	1	hSpCas9	negative selection	8792315
43317660	43317683	1	-	27260156	PATU8988T	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.4989654300595472	[517]	[868,648,720,573]	8	hSpCas9	negative selection	8792316
43313336	43313359	1	-	27260156	T47D	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.0017765693497669988	[406]	[456,519,429,483]	0	hSpCas9	negative selection	8849312
43317583	43317606	1	-	27260156	T47D	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.06576743794914597	[206]	[232,255,264,254]	1	hSpCas9	negative selection	8849313
43313342	43313365	1	+	27260156	T47D	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.34020599375914784	[1010]	[860,846,938,1085]	-6	hSpCas9	negative selection	8849314
43317318	43317341	1	-	27260156	T47D	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.40630445042812924	[1287]	[1269,1025,1041,1203]	-7	hSpCas9	negative selection	8913565
43317332	43317355	1	+	27260156	T47D	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.1460091851368608	[271]	[280,251,281,334]	-3	hSpCas9	negative selection	8913566
43317660	43317683	1	-	27260156	T47D	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.2693376220486997	[517]	[716,629,753,818]	6	hSpCas9	negative selection	8913567
43313336	43313359	1	-	27260156	SU8686	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.17862553499238656	[406]	[431,360,314,294]	-3	hSpCas9	negative selection	8970563
43317583	43317606	1	-	27260156	SU8686	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.11211035653089607	[206]	[211,190,179,322]	1	hSpCas9	negative selection	8970564
43313342	43313365	1	+	27260156	SU8686	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.3100094004914742	[1010]	[793,640,834,1015]	-5	hSpCas9	negative selection	8970565
43317318	43317341	1	-	27260156	SU8686	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.1862064301354176	[1287]	[1031,1047,1110,1345]	-3	hSpCas9	negative selection	9034816
43317332	43317355	1	+	27260156	SU8686	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.06214039251029135	[271]	[202,307,287,227]	-1	hSpCas9	negative selection	9034817
43317660	43317683	1	-	27260156	SU8686	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.25840029094682093	[517]	[649,570,520,727]	4	hSpCas9	negative selection	9034818
43313336	43313359	1	-	27260156	SKES1	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.10093853905566566	[406]	[331,486,313,383]	-2	hSpCas9	negative selection	9091814
43317583	43317606	1	-	27260156	SKES1	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.21924819576693677	[206]	[307,219,182,253]	5	hSpCas9	negative selection	9091815
43313342	43313365	1	+	27260156	SKES1	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.4846011991680578	[1010]	[912,760,642,604]	-8	hSpCas9	negative selection	9091816
43317318	43317341	1	-	27260156	SKES1	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.2530353796075049	[1287]	[1243,1051,993,1036]	-5	hSpCas9	negative selection	9156067
43317332	43317355	1	+	27260156	SKES1	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.1909985370998475	[271]	[218,460,303,262]	4	hSpCas9	negative selection	9156068
43317660	43317683	1	-	27260156	SKES1	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.5521470589126141	[517]	[809,761,731,729]	9	hSpCas9	negative selection	9156069
43313336	43313359	1	-	27260156	TOV112D	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.1005041024138824	[406]	[503,731,345,248]	2	hSpCas9	negative selection	9213065
43317583	43317606	1	-	27260156	TOV112D	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.41628292340891604	[206]	[469,246,150,247]	7	hSpCas9	negative selection	9213066
43313342	43313365	1	+	27260156	TOV112D	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.16328426411479635	[1010]	[880,1253,497,1061]	-3	hSpCas9	negative selection	9213067
43317318	43317341	1	-	27260156	TOV112D	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.10021351023983671	[1287]	[1135,1481,994,1259]	-2	hSpCas9	negative selection	9277318
43317332	43317355	1	+	27260156	TOV112D	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.3058540749678061	[271]	[387,331,270,357]	6	hSpCas9	negative selection	9277319
43317660	43317683	1	-	27260156	TOV112D	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.23429340883372746	[517]	[639,520,661,597]	4	hSpCas9	negative selection	9277320
43313336	43313359	1	-	27260156	TC71	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	-0.21544259039074223	[406]	[354,334,390,424]	-5	hSpCas9	negative selection	9334316
43317583	43317606	1	-	27260156	TC71	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.26106157557553655	[206]	[265,349,206,240]	6	hSpCas9	negative selection	9334317
43313342	43313365	1	+	27260156	TC71	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.2528919276560404	[1010]	[885,951,900,898]	-6	hSpCas9	negative selection	9334318
43317318	43317341	1	-	27260156	TC71	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.07834726569759254	[1287]	[1204,1236,1440,1347]	-2	hSpCas9	negative selection	9398569
43317332	43317355	1	+	27260156	TC71	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	0.23490260440730393	[271]	[321,277,408,362]	6	hSpCas9	negative selection	9398570
43317660	43317683	1	-	27260156	TC71	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.183201043963776	[517]	[493,586,677,772]	4	hSpCas9	negative selection	9398571
43313336	43313359	1	-	27260156	TC32	viability	GCGGAAGAGGTAGCGCGTGCTGG	TIE1	ENSG00000066056	0.14244772576898274	[406]	[285,347,675,444]	2	hSpCas9	negative selection	9455567
43317583	43317606	1	-	27260156	TC32	viability	GTTCTCCCGCAAAGTCACGATGG	TIE1	ENSG00000066056	0.25191876829301296	[206]	[174,208,327,232]	4	hSpCas9	negative selection	9455568
43313342	43313365	1	+	27260156	TC32	viability	CGCGCTACCTCTTCCGCATGCGG	TIE1	ENSG00000066056	-0.532490182144097	[1010]	[709,424,867,705]	-8	hSpCas9	negative selection	9455569
43317318	43317341	1	-	27260156	TC32	viability	CGAAGTTCCCCTCCCCGATGAGG	TIE1	ENSG00000066056	-0.1282967260661394	[1287]	[1204,739,1390,1208]	-2	hSpCas9	negative selection	9519820
43317332	43317355	1	+	27260156	TC32	viability	GGAACTTCGGCCAGGTCATCCGG	TIE1	ENSG00000066056	-0.011058265737046158	[271]	[204,160,397,305]	0	hSpCas9	negative selection	9519821
43317660	43317683	1	-	27260156	TC32	viability	GGGCTCACCTCGGTTCTTACAGG	TIE1	ENSG00000066056	0.35558820552014386	[517]	[726,484,770,527]	6	hSpCas9	negative selection	9519822
43301107	43301130	1	-	27869803	HPAFII	viability after 27 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.3702374463322968	[641]	[360,498,NaN]	3	hSpCas9	negative selection	9534500
43305141	43305164	1	+	27869803	HPAFII	viability after 27 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	-0.40304939323454575	[256]	[111,93,NaN]	-3	hSpCas9	negative selection	9534501
43306959	43306982	1	-	27869803	HPAFII	viability after 27 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-1.7888868294739446	[287]	[69,21,NaN]	-8	hSpCas9	negative selection	9534502
43307186	43307209	1	-	27869803	HPAFII	viability after 27 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.7111569908334996	[401]	[225,445,NaN]	6	hSpCas9	negative selection	9534503
43307559	43307582	1	-	27869803	HPAFII	viability after 27 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.22873153476484015	[205]	[61,180,NaN]	1	hSpCas9	negative selection	9534504
43307833	43307856	1	-	27869803	HPAFII	viability after 27 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.5073063067307128	[367]	[370,194,NaN]	4	hSpCas9	negative selection	9534505
43301107	43301130	1	-	27869803	HPAFII	viability after 15 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.11586013376567328	[641]	[989,596,NaN]	1	hSpCas9	negative selection	9616949
43305141	43305164	1	+	27869803	HPAFII	viability after 15 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	-0.913850584926634	[256]	[153,141,NaN]	-7	hSpCas9	negative selection	9616950
43306959	43306982	1	-	27869803	HPAFII	viability after 15 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-1.47528723529478	[287]	[180,67,NaN]	-8	hSpCas9	negative selection	9616951
43307186	43307209	1	-	27869803	HPAFII	viability after 15 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	-0.06963948847138168	[401]	[571,311,NaN]	0	hSpCas9	negative selection	9616952
43307559	43307582	1	-	27869803	HPAFII	viability after 15 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.24648511462655034	[205]	[364,198,NaN]	3	hSpCas9	negative selection	9616953
43307833	43307856	1	-	27869803	HPAFII	viability after 15 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.2574162790021246	[367]	[711,323,NaN]	3	hSpCas9	negative selection	9616954
43301107	43301130	1	-	27869803	ASPC1	viability after 36 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.19143071438518255	[1672]	[536,982,499]	2	hSpCas9	negative selection	9699398
43305141	43305164	1	+	27869803	ASPC1	viability after 36 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	0.0021858837499202158	[605]	[35,163,370]	0	hSpCas9	negative selection	9699399
43306959	43306982	1	-	27869803	ASPC1	viability after 36 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-0.6756105929439911	[773]	[137,176,182]	-6	hSpCas9	negative selection	9699400
43307186	43307209	1	-	27869803	ASPC1	viability after 36 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	-0.0908047604912171	[1074]	[199,182,589]	-1	hSpCas9	negative selection	9699401
43307559	43307582	1	-	27869803	ASPC1	viability after 36 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.2084544889691182	[542]	[199,111,314]	2	hSpCas9	negative selection	9699402
43307833	43307856	1	-	27869803	ASPC1	viability after 36 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.3142535078817312	[708]	[177,359,353]	3	hSpCas9	negative selection	9699403
43301107	43301130	1	-	27869803	PATU8988S	viability after 35 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	-0.33398580630468344	[1462]	[447,486,NaN]	-4	hSpCas9	negative selection	9781847
43305141	43305164	1	+	27869803	PATU8988S	viability after 35 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	1.914708013887668	[326]	[520,471,NaN]	9	hSpCas9	negative selection	9781848
43306959	43306982	1	-	27869803	PATU8988S	viability after 35 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	0.1605481103641097	[651]	[294,291,NaN]	1	hSpCas9	negative selection	9781849
43307186	43307209	1	-	27869803	PATU8988S	viability after 35 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.8177548585959817	[696]	[410,578,NaN]	8	hSpCas9	negative selection	9781850
43307559	43307582	1	-	27869803	PATU8988S	viability after 35 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.5070298723367593	[509]	[248,334,NaN]	5	hSpCas9	negative selection	9781851
43307833	43307856	1	-	27869803	PATU8988S	viability after 35 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.5746707958969695	[797]	[331,625,NaN]	6	hSpCas9	negative selection	9781852
43301107	43301130	1	-	27869803	PATU8988S	viability after 31 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	-0.37809787828055197	[1462]	[392,519,NaN]	-4	hSpCas9	negative selection	9864296
43305141	43305164	1	+	27869803	PATU8988S	viability after 31 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	1.870431795311632	[326]	[463,492,NaN]	9	hSpCas9	negative selection	9864297
43306959	43306982	1	-	27869803	PATU8988S	viability after 31 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	0.5224538221878612	[651]	[350,401,NaN]	6	hSpCas9	negative selection	9864298
43307186	43307209	1	-	27869803	PATU8988S	viability after 31 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.757530716359379	[696]	[358,610,NaN]	8	hSpCas9	negative selection	9864299
43307559	43307582	1	-	27869803	PATU8988S	viability after 31 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.8572216934727089	[509]	[341,401,NaN]	8	hSpCas9	negative selection	9864300
43307833	43307856	1	-	27869803	PATU8988S	viability after 31 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.15489016263705102	[797]	[260,472,NaN]	2	hSpCas9	negative selection	9864301
43301107	43301130	1	-	27869803	HPAFII	viability after 35 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.9144531758126637	[641]	[391,860,NaN]	6	hSpCas9	negative selection	9946745
43305141	43305164	1	+	27869803	HPAFII	viability after 35 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	-0.3882587913112614	[256]	[89,109,NaN]	-2	hSpCas9	negative selection	9946746
43306959	43306982	1	-	27869803	HPAFII	viability after 35 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-2.5540514691398077	[287]	[29,18,NaN]	-8	hSpCas9	negative selection	9946747
43307186	43307209	1	-	27869803	HPAFII	viability after 35 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.6738581777378339	[401]	[128,544,NaN]	4	hSpCas9	negative selection	9946748
43307559	43307582	1	-	27869803	HPAFII	viability after 35 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	-0.16390484985804654	[205]	[30,162,NaN]	-1	hSpCas9	negative selection	9946749
43307833	43307856	1	-	27869803	HPAFII	viability after 35 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.7404886849553877	[367]	[354,261,NaN]	5	hSpCas9	negative selection	9946750
43301107	43301130	1	-	27869803	HPAFII	viability after 31 days	CCACATGAGAAGCCAAGAAGAGG	TIE1	ENSG00000066056	0.7571893661938696	[641]	[440,791,NaN]	5	hSpCas9	negative selection	10029194
43305141	43305164	1	+	27869803	HPAFII	viability after 31 days	ATCTACGTGCACAACAGCCCTGG	TIE1	ENSG00000066056	-0.48125766364662476	[256]	[76,131,NaN]	-3	hSpCas9	negative selection	10029195
43306959	43306982	1	-	27869803	HPAFII	viability after 31 days	CGAAAGAAGGCGCTGCCCAGGGG	TIE1	ENSG00000066056	-2.0842938675274363	[287]	[62,10,NaN]	-8	hSpCas9	negative selection	10029196
43307186	43307209	1	-	27869803	HPAFII	viability after 31 days	ACACCTCCATGTAGGCAACCTGG	TIE1	ENSG00000066056	0.9459350051685445	[401]	[213,674,NaN]	7	hSpCas9	negative selection	10029197
43307559	43307582	1	-	27869803	HPAFII	viability after 31 days	TAGGCATACCTTCTTGGCACTGG	TIE1	ENSG00000066056	0.011499022526299474	[205]	[27,212,NaN]	0	hSpCas9	negative selection	10029198
43307833	43307856	1	-	27869803	HPAFII	viability after 31 days	CACCATTCTGACACTGGCACTGG	TIE1	ENSG00000066056	0.522427216190874	[367]	[299,292,NaN]	4	hSpCas9	negative selection	10029199
43317230	43317253	1	+	28162770	P31FUJ	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	-0.12795983855688053	[198]	[213]	-1	hSpCas9	negative selection	10250615
43311717	43311740	1	-	28162770	P31FUJ	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	0.2876715698550639	[121]	[174]	3	hSpCas9	negative selection	10250616
43304900	43304923	1	-	28162770	P31FUJ	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.36207576517186024	[144]	[218]	4	hSpCas9	negative selection	10250617
43305281	43305304	1	-	28162770	P31FUJ	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	0.44791927911220836	[135]	[217]	5	hSpCas9	negative selection	10250618
43307242	43307265	1	-	28162770	P31FUJ	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	0.36313141412778066	[130]	[197]	4	hSpCas9	negative selection	10250619
43307499	43307522	1	-	28162770	P31FUJ	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-5.057230639830925	[84]	[2]	-9	hSpCas9	negative selection	10250620
43307887	43307910	1	-	28162770	P31FUJ	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	0.38898056985171503	[489]	[753]	4	hSpCas9	negative selection	10250621
43309045	43309068	1	-	28162770	P31FUJ	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	0.00019831648805013202	[541]	[636]	0	hSpCas9	negative selection	10250622
43309076	43309099	1	-	28162770	P31FUJ	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.8991631357941263	[260]	[571]	8	hSpCas9	negative selection	10250623
43309419	43309442	1	-	28162770	P31FUJ	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	0.027587480163851597	[272]	[326]	0	hSpCas9	negative selection	10250624
43317230	43317253	1	+	28162770	TF1	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10419981
43311717	43311740	1	-	28162770	TF1	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10419982
43304900	43304923	1	-	28162770	TF1	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10419983
43305281	43305304	1	-	28162770	TF1	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	NaN	[NaN]	[99]	1	hSpCas9	negative selection	10419984
43307242	43307265	1	-	28162770	TF1	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10419985
43307499	43307522	1	-	28162770	TF1	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10419986
43307887	43307910	1	-	28162770	TF1	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	NaN	[NaN]	[355]	1	hSpCas9	negative selection	10419987
43309045	43309068	1	-	28162770	TF1	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10419988
43309076	43309099	1	-	28162770	TF1	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	NaN	[NaN]	[401]	1	hSpCas9	negative selection	10419989
43309419	43309442	1	-	28162770	TF1	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10419990
43317230	43317253	1	+	28162770	SKM1	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	0.3959033323221287	[45]	[106]	4	hSpCas9	negative selection	10589347
43311717	43311740	1	-	28162770	SKM1	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	0.25328642928223155	[27]	[58]	2	hSpCas9	negative selection	10589348
43304900	43304923	1	-	28162770	SKM1	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.8942053359774033	[34]	[114]	8	hSpCas9	negative selection	10589349
43305281	43305304	1	-	28162770	SKM1	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	0.8784380201190869	[31]	[103]	8	hSpCas9	negative selection	10589350
43307242	43307265	1	-	28162770	SKM1	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	-0.12539384147194044	[28]	[46]	-1	hSpCas9	negative selection	10589351
43307499	43307522	1	-	28162770	SKM1	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-2.538208732021414	[22]	[6]	-9	hSpCas9	negative selection	10589352
43307887	43307910	1	-	28162770	SKM1	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	-0.37089494403564016	[157]	[215]	-3	hSpCas9	negative selection	10589353
43309045	43309068	1	-	28162770	SKM1	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-0.310840497710966	[126]	[180]	-3	hSpCas9	negative selection	10589354
43309076	43309099	1	-	28162770	SKM1	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.8282522629508697	[71]	[225]	7	hSpCas9	negative selection	10589355
43309419	43309442	1	-	28162770	SKM1	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	0.1779983019779943	[58]	[117]	1	hSpCas9	negative selection	10589356
43317230	43317253	1	+	28162770	SKM1	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	0.3959033323221287	[45]	[106]	4	hSpCas9	negative selection	10758713
43311717	43311740	1	-	28162770	SKM1	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	0.25328642928223155	[27]	[58]	2	hSpCas9	negative selection	10758714
43304900	43304923	1	-	28162770	SKM1	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.8942053359774033	[34]	[114]	8	hSpCas9	negative selection	10758715
43305281	43305304	1	-	28162770	SKM1	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	0.8784380201190869	[31]	[103]	8	hSpCas9	negative selection	10758716
43307242	43307265	1	-	28162770	SKM1	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	-0.12539384147194044	[28]	[46]	-1	hSpCas9	negative selection	10758717
43307499	43307522	1	-	28162770	SKM1	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-2.538208732021414	[22]	[6]	-9	hSpCas9	negative selection	10758718
43307887	43307910	1	-	28162770	SKM1	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	-0.37089494403564016	[157]	[215]	-3	hSpCas9	negative selection	10758719
43309045	43309068	1	-	28162770	SKM1	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-0.310840497710966	[126]	[180]	-3	hSpCas9	negative selection	10758720
43309076	43309099	1	-	28162770	SKM1	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.8282522629508697	[71]	[225]	7	hSpCas9	negative selection	10758721
43309419	43309442	1	-	28162770	SKM1	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	0.1779983019779943	[58]	[117]	1	hSpCas9	negative selection	10758722
43317230	43317253	1	+	28162770	PL21	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	0.6876896135525319	[193]	[135]	6	hSpCas9	negative selection	10928079
43311717	43311740	1	-	28162770	PL21	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	0.6728926116244514	[97]	[67]	6	hSpCas9	negative selection	10928080
43304900	43304923	1	-	28162770	PL21	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.4631740203231139	[194]	[116]	4	hSpCas9	negative selection	10928081
43305281	43305304	1	-	28162770	PL21	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	0.3539449505683556	[159]	[88]	3	hSpCas9	negative selection	10928082
43307242	43307265	1	-	28162770	PL21	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	-0.48791637919593955	[173]	[53]	-3	hSpCas9	negative selection	10928083
43307499	43307522	1	-	28162770	PL21	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-1.2372656978179781	[64]	[11]	-7	hSpCas9	negative selection	10928084
43307887	43307910	1	-	28162770	PL21	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	0.4745787835953632	[419]	[253]	4	hSpCas9	negative selection	10928085
43309045	43309068	1	-	28162770	PL21	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-0.4227907364308564	[384]	[124]	-3	hSpCas9	negative selection	10928086
43309076	43309099	1	-	28162770	PL21	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.6985931219558014	[251]	[177]	6	hSpCas9	negative selection	10928087
43309419	43309442	1	-	28162770	PL21	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	0.6640867142491105	[202]	[139]	6	hSpCas9	negative selection	10928088
43317230	43317253	1	+	28162770	P31FUJ	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	-0.12795983855688053	[198]	[213]	-1	hSpCas9	negative selection	11097445
43311717	43311740	1	-	28162770	P31FUJ	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	0.2876715698550639	[121]	[174]	3	hSpCas9	negative selection	11097446
43304900	43304923	1	-	28162770	P31FUJ	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.36207576517186024	[144]	[218]	4	hSpCas9	negative selection	11097447
43305281	43305304	1	-	28162770	P31FUJ	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	0.44791927911220836	[135]	[217]	5	hSpCas9	negative selection	11097448
43307242	43307265	1	-	28162770	P31FUJ	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	0.36313141412778066	[130]	[197]	4	hSpCas9	negative selection	11097449
43307499	43307522	1	-	28162770	P31FUJ	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-5.057230639830925	[84]	[2]	-9	hSpCas9	negative selection	11097450
43307887	43307910	1	-	28162770	P31FUJ	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	0.38898056985171503	[489]	[753]	4	hSpCas9	negative selection	11097451
43309045	43309068	1	-	28162770	P31FUJ	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	0.00019831648805013202	[541]	[636]	0	hSpCas9	negative selection	11097452
43309076	43309099	1	-	28162770	P31FUJ	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.8991631357941263	[260]	[571]	8	hSpCas9	negative selection	11097453
43309419	43309442	1	-	28162770	P31FUJ	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	0.027587480163851597	[272]	[326]	0	hSpCas9	negative selection	11097454
43317230	43317253	1	+	28162770	OCIAML5	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	0.025449422611008243	[85]	[157]	0	hSpCas9	negative selection	11266811
43311717	43311740	1	-	28162770	OCIAML5	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	0.5751046840507021	[73]	[198]	5	hSpCas9	negative selection	11266812
43304900	43304923	1	-	28162770	OCIAML5	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.7588911383901036	[54]	[167]	6	hSpCas9	negative selection	11266813
43305281	43305304	1	-	28162770	OCIAML5	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	1.6286685609815228	[54]	[306]	9	hSpCas9	negative selection	11266814
43307242	43307265	1	-	28162770	OCIAML5	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	0.9322047380805656	[71]	[247]	7	hSpCas9	negative selection	11266815
43307499	43307522	1	-	28162770	OCIAML5	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-0.7696044106720239	[33]	[35]	-5	hSpCas9	negative selection	11266816
43307887	43307910	1	-	28162770	OCIAML5	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	0.6107050506459344	[352]	[972]	5	hSpCas9	negative selection	11266817
43309045	43309068	1	-	28162770	OCIAML5	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-0.34345495627295575	[290]	[413]	-2	hSpCas9	negative selection	11266818
43309076	43309099	1	-	28162770	OCIAML5	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.8905298446605322	[178]	[598]	7	hSpCas9	negative selection	11266819
43309419	43309442	1	-	28162770	OCIAML5	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	-0.2268113641948076	[152]	[235]	-2	hSpCas9	negative selection	11266820
43317230	43317253	1	+	28162770	EOL1	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	0.26121949684419965	[330]	[208]	2	hSpCas9	negative selection	11436177
43311717	43311740	1	-	28162770	EOL1	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	-0.5524993899837343	[102]	[36]	-4	hSpCas9	negative selection	11436178
43304900	43304923	1	-	28162770	EOL1	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.4965546171877777	[260]	[193]	4	hSpCas9	negative selection	11436179
43305281	43305304	1	-	28162770	EOL1	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	0.8737434008990433	[288]	[278]	7	hSpCas9	negative selection	11436180
43307242	43307265	1	-	28162770	EOL1	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	-0.2911809194849026	[287]	[123]	-2	hSpCas9	negative selection	11436181
43307499	43307522	1	-	28162770	EOL1	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-1.1909294458494013	[129]	[29]	-7	hSpCas9	negative selection	11436182
43307887	43307910	1	-	28162770	EOL1	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	-0.18334295137759382	[568]	[263]	-1	hSpCas9	negative selection	11436183
43309045	43309068	1	-	28162770	EOL1	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-0.04026279996716531	[485]	[248]	0	hSpCas9	negative selection	11436184
43309076	43309099	1	-	28162770	EOL1	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.0944727730128469	[271]	[152]	0	hSpCas9	negative selection	11436185
43309419	43309442	1	-	28162770	EOL1	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	-0.21767430108193014	[244]	[110]	-2	hSpCas9	negative selection	11436186
43317230	43317253	1	+	28162770	MOLM13	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	0.7674496634034866	[233]	[287]	6	hSpCas9	negative selection	11605543
43311717	43311740	1	-	28162770	MOLM13	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	-1.3197022856915952	[144]	[41]	-6	hSpCas9	negative selection	11605544
43304900	43304923	1	-	28162770	MOLM13	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	1.0562108943556494	[142]	[214]	7	hSpCas9	negative selection	11605545
43305281	43305304	1	-	28162770	MOLM13	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	0.30414295503139066	[232]	[207]	2	hSpCas9	negative selection	11605546
43307242	43307265	1	-	28162770	MOLM13	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	0.7776720465698519	[166]	[206]	6	hSpCas9	negative selection	11605547
43307499	43307522	1	-	28162770	MOLM13	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-2.6364472782701567	[85]	[9]	-8	hSpCas9	negative selection	11605548
43307887	43307910	1	-	28162770	MOLM13	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	0.742266473886305	[548]	[663]	5	hSpCas9	negative selection	11605549
43309045	43309068	1	-	28162770	MOLM13	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-1.3306953308852931	[573]	[164]	-6	hSpCas9	negative selection	11605550
43309076	43309099	1	-	28162770	MOLM13	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	1.130854394267008	[251]	[398]	8	hSpCas9	negative selection	11605551
43309419	43309442	1	-	28162770	MOLM13	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	0.38570362618933396	[306]	[289]	3	hSpCas9	negative selection	11605552
43317230	43317253	1	+	28162770	HEL	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	0.9700003711907599	[215]	[270]	8	hSpCas9	negative selection	11774909
43311717	43311740	1	-	28162770	HEL	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	-0.7411761497827063	[106]	[40]	-5	hSpCas9	negative selection	11774910
43304900	43304923	1	-	28162770	HEL	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.5628855243111424	[129]	[122]	5	hSpCas9	negative selection	11774911
43305281	43305304	1	-	28162770	HEL	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	-0.19679649580639694	[203]	[113]	-1	hSpCas9	negative selection	11774912
43307242	43307265	1	-	28162770	HEL	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	0.9249406485721086	[161]	[196]	7	hSpCas9	negative selection	11774913
43307499	43307522	1	-	28162770	HEL	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-1.113990016987279	[97]	[28]	-6	hSpCas9	negative selection	11774914
43307887	43307910	1	-	28162770	HEL	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	0.6060581686738886	[477]	[465]	5	hSpCas9	negative selection	11774915
43309045	43309068	1	-	28162770	HEL	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-1.494764691749578	[461]	[104]	-7	hSpCas9	negative selection	11774916
43309076	43309099	1	-	28162770	HEL	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	-0.017185726402021165	[236]	[149]	0	hSpCas9	negative selection	11774917
43309419	43309442	1	-	28162770	HEL	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	-0.8247003652383064	[270]	[97]	-5	hSpCas9	negative selection	11774918
43317230	43317253	1	+	28162770	MV411	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	-0.7437385988302186	[162]	[81]	-5	hSpCas9	negative selection	11944275
43311717	43311740	1	-	28162770	MV411	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	-1.426334216896237	[66]	[20]	-7	hSpCas9	negative selection	11944276
43304900	43304923	1	-	28162770	MV411	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.03798418515382551	[147]	[127]	0	hSpCas9	negative selection	11944277
43305281	43305304	1	-	28162770	MV411	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	-0.5221327088153586	[178]	[104]	-4	hSpCas9	negative selection	11944278
43307242	43307265	1	-	28162770	MV411	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	1.2316702349244586	[91]	[181]	9	hSpCas9	negative selection	11944279
43307499	43307522	1	-	28162770	MV411	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-0.3375249499383808	[50]	[33]	-3	hSpCas9	negative selection	11944280
43307887	43307910	1	-	28162770	MV411	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	0.0800864930042895	[419]	[373]	0	hSpCas9	negative selection	11944281
43309045	43309068	1	-	28162770	MV411	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-0.9352157555024594	[369]	[162]	-6	hSpCas9	negative selection	11944282
43309076	43309099	1	-	28162770	MV411	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.1934426611420459	[244]	[235]	1	hSpCas9	negative selection	11944283
43309419	43309442	1	-	28162770	MV411	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	0.3222053191847473	[187]	[197]	3	hSpCas9	negative selection	11944284
43317230	43317253	1	+	28162770	MONOMAC1	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	-0.11973112089210494	[108]	[114]	-1	hSpCas9	negative selection	12113641
43311717	43311740	1	-	28162770	MONOMAC1	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	-0.1970368470595536	[59]	[59]	-2	hSpCas9	negative selection	12113642
43304900	43304923	1	-	28162770	MONOMAC1	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	-0.40562346887097117	[103]	[89]	-4	hSpCas9	negative selection	12113643
43305281	43305304	1	-	28162770	MONOMAC1	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	0.7047827590015429	[113]	[212]	6	hSpCas9	negative selection	12113644
43307242	43307265	1	-	28162770	MONOMAC1	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	-0.8151662117159092	[65]	[42]	-6	hSpCas9	negative selection	12113645
43307499	43307522	1	-	28162770	MONOMAC1	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-1.974644425723106	[47]	[13]	-8	hSpCas9	negative selection	12113646
43307887	43307910	1	-	28162770	MONOMAC1	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	1.02114332298998	[244]	[569]	8	hSpCas9	negative selection	12113647
43309045	43309068	1	-	28162770	MONOMAC1	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	0.49880975978106	[241]	[391]	5	hSpCas9	negative selection	12113648
43309076	43309099	1	-	28162770	MONOMAC1	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.24415294007525873	[122]	[166]	2	hSpCas9	negative selection	12113649
43309419	43309442	1	-	28162770	MONOMAC1	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	-0.48880297143666374	[141]	[115]	-4	hSpCas9	negative selection	12113650
43317230	43317253	1	+	28162770	OCIAML2	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	-0.4024583226005819	[30]	[129]	-3	hSpCas9	negative selection	12283007
43311717	43311740	1	-	28162770	OCIAML2	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	0.4951544594199261	[15]	[124]	5	hSpCas9	negative selection	12283008
43304900	43304923	1	-	28162770	OCIAML2	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	0.9715925033629131	[22]	[249]	8	hSpCas9	negative selection	12283009
43305281	43305304	1	-	28162770	OCIAML2	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	0.4469080145658658	[26]	[203]	4	hSpCas9	negative selection	12283010
43307242	43307265	1	-	28162770	OCIAML2	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	-0.2689959640725106	[29]	[137]	-2	hSpCas9	negative selection	12283011
43307499	43307522	1	-	28162770	OCIAML2	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-0.5580926664925008	[16]	[63]	-4	hSpCas9	negative selection	12283012
43307887	43307910	1	-	28162770	OCIAML2	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	0.35854320702113385	[74]	[532]	3	hSpCas9	negative selection	12283013
43309045	43309068	1	-	28162770	OCIAML2	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	-0.20076338592594223	[78]	[380]	-2	hSpCas9	negative selection	12283014
43309076	43309099	1	-	28162770	OCIAML2	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.9514349409306511	[31]	[342]	8	hSpCas9	negative selection	12283015
43309419	43309442	1	-	28162770	OCIAML2	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	0.3080138001739153	[28]	[198]	3	hSpCas9	negative selection	12283016
43317230	43317253	1	+	28162770	OCIAML3	viability	GGACCTTGACACTTACCCGGCGG	TIE1	ENSG00000066056	-1.689164873364503	[46]	[43]	-8	hSpCas9	negative selection	12452373
43311717	43311740	1	-	28162770	OCIAML3	viability	GCGGGGAGACCACAAGCTGGCGG	TIE1	ENSG00000066056	-0.6200028488571075	[27]	[54]	-5	hSpCas9	negative selection	12452374
43304900	43304923	1	-	28162770	OCIAML3	viability	CGCAAGTCAGGAAGAAGCGCTGG	TIE1	ENSG00000066056	-0.548683649814673	[46]	[96]	-4	hSpCas9	negative selection	12452375
43305281	43305304	1	-	28162770	OCIAML3	viability	CACACGTGCAGAAAGTACAGCGG	TIE1	ENSG00000066056	-0.04381055776368359	[27]	[81]	0	hSpCas9	negative selection	12452376
43307242	43307265	1	-	28162770	OCIAML3	viability	AGCGGGTGCCAGTGAAGCCAGGG	TIE1	ENSG00000066056	0.44552072386247443	[35]	[147]	4	hSpCas9	negative selection	12452377
43307499	43307522	1	-	28162770	OCIAML3	viability	GGTCTGGGAGGCAGAAGGTGAGG	TIE1	ENSG00000066056	-2.9863250631029237	[20]	[7]	-9	hSpCas9	negative selection	12452378
43307887	43307910	1	-	28162770	OCIAML3	viability	GCACTCCATGCCACCCAGAGGGG	TIE1	ENSG00000066056	0.5771991870939792	[124]	[562]	5	hSpCas9	negative selection	12452379
43309045	43309068	1	-	28162770	OCIAML3	viability	GCAGCTGCACAGTTGATCCGGGG	TIE1	ENSG00000066056	0.5585914849578664	[120]	[537]	5	hSpCas9	negative selection	12452380
43309076	43309099	1	-	28162770	OCIAML3	viability	TATGCTGCCCCGCACGGGGAAGG	TIE1	ENSG00000066056	0.03339012671738967	[66]	[206]	0	hSpCas9	negative selection	12452381
43309419	43309442	1	-	28162770	OCIAML3	viability	GGGCACCTCGAACTCAGCTGTGG	TIE1	ENSG00000066056	-0.6346496248215091	[53]	[104]	-5	hSpCas9	negative selection	12452382