Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7084
• Symbol:TK2
• Description:thymidine kinase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/TK2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
66513769	66513792	16	+	26472758	Jiyoye	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.17778381949971545	[550]	[469]	1	hSpCas9	negative selection	165939
66517835	66517858	16	-	26472758	Jiyoye	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	0.7249156794298025	[68]	[85]	5	hSpCas9	negative selection	165940
66513745	66513768	16	-	26472758	Jiyoye	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.9979202348210356	[165]	[249]	6	hSpCas9	negative selection	165941
66513719	66513742	16	+	26472758	Jiyoye	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	0.32351745245896385	[70]	[66]	2	hSpCas9	negative selection	165942
66531436	66531459	16	+	26472758	Jiyoye	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	2.1402365212161634	[36]	[122]	9	hSpCas9	negative selection	165943
66517160	66517183	16	-	26472758	Jiyoye	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.6030955914811305	[54]	[62]	4	hSpCas9	negative selection	165944
66517135	66517158	16	-	26472758	Jiyoye	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	0.28431863372034005	[48]	[44]	2	hSpCas9	negative selection	165945
66513730	66513753	16	+	26472758	Jiyoye	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	1.5311640987813266	[38]	[84]	8	hSpCas9	negative selection	165946
66517189	66517212	16	+	26472758	Jiyoye	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.5362410901277592	[199]	[103]	-4	hSpCas9	negative selection	165947
66529041	66529064	16	-	26472758	Jiyoye	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.36410665961398747	[33]	[32]	2	hSpCas9	negative selection	165948
66513769	66513792	16	+	26472758	KBM7	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.30775783509007537	[2069,1447]	[1119,911]	3	hSpCas9	negative selection	357057
66517835	66517858	16	-	26472758	KBM7	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	0.22424441409234075	[316,433]	[190,227]	2	hSpCas9	negative selection	357058
66513745	66513768	16	-	26472758	KBM7	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.4232740725877022	[918,520]	[351,524]	4	hSpCas9	negative selection	357059
66513719	66513742	16	+	26472758	KBM7	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	-1.5263108502454092	[218,190]	[25,39]	-8	hSpCas9	negative selection	357060
66531436	66531459	16	+	26472758	KBM7	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	-0.18519241461137015	[419,397]	[178,160]	-2	hSpCas9	negative selection	357061
66517160	66517183	16	-	26472758	KBM7	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.18622476824066586	[548,371]	[200,279]	2	hSpCas9	negative selection	357062
66517135	66517158	16	-	26472758	KBM7	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	0.5750129947563908	[262,234]	[244,110]	6	hSpCas9	negative selection	357063
66513730	66513753	16	+	26472758	KBM7	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	0.5691712649650599	[206,212]	[129,162]	6	hSpCas9	negative selection	357064
66517189	66517212	16	+	26472758	KBM7	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.2765794021870924	[708,560]	[441,284]	3	hSpCas9	negative selection	357065
66529041	66529064	16	-	26472758	KBM7	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.21255188586906604	[233,224]	[85,99]	-2	hSpCas9	negative selection	357066
66513769	66513792	16	+	26472758	Raji	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.2621061301722416	[847]	[235]	2	hSpCas9	negative selection	548175
66517835	66517858	16	-	26472758	Raji	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	1.1073835353735995	[165]	[82]	8	hSpCas9	negative selection	548176
66513745	66513768	16	-	26472758	Raji	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.4500125391243932	[428]	[135]	4	hSpCas9	negative selection	548177
66513719	66513742	16	+	26472758	Raji	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	1.5548425123448206	[43]	[29]	9	hSpCas9	negative selection	548178
66531436	66531459	16	+	26472758	Raji	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	-0.15357654222233608	[138]	[28]	-1	hSpCas9	negative selection	548179
66517160	66517183	16	-	26472758	Raji	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.17872231709386183	[216]	[56]	1	hSpCas9	negative selection	548180
66517135	66517158	16	-	26472758	Raji	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	-0.37804329179664226	[195]	[34]	-3	hSpCas9	negative selection	548181
66513730	66513753	16	+	26472758	Raji	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	1.0558532347335174	[113]	[54]	8	hSpCas9	negative selection	548182
66517189	66517212	16	+	26472758	Raji	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.2100986544825706	[323]	[64]	-2	hSpCas9	negative selection	548183
66529041	66529064	16	-	26472758	Raji	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.3995642868669096	[97]	[29]	4	hSpCas9	negative selection	548184
66513769	66513792	16	+	26472758	K562	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.6057305595620999	[1401]	[1800]	5	hSpCas9	negative selection	739293
66517835	66517858	16	-	26472758	K562	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	0.60299241934086	[240]	[308]	5	hSpCas9	negative selection	739294
66513745	66513768	16	-	26472758	K562	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.10578985671367291	[512]	[465]	0	hSpCas9	negative selection	739295
66513719	66513742	16	+	26472758	K562	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	1.4167342765337532	[133]	[301]	9	hSpCas9	negative selection	739296
66531436	66531459	16	+	26472758	K562	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.13040246737479091	[328]	[303]	0	hSpCas9	negative selection	739297
66517160	66517183	16	-	26472758	K562	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	-0.6968286850494638	[408]	[212]	-4	hSpCas9	negative selection	739298
66517135	66517158	16	-	26472758	K562	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	1.198615038053322	[159]	[309]	8	hSpCas9	negative selection	739299
66513730	66513753	16	+	26472758	K562	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	-0.018615678167346994	[155]	[129]	0	hSpCas9	negative selection	739300
66517189	66517212	16	+	26472758	K562	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.3888086370016216	[512]	[566]	3	hSpCas9	negative selection	739301
66529041	66529064	16	-	26472758	K562	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.8972533412800616	[172]	[271]	7	hSpCas9	negative selection	739302
66513798	66513821	16	+	26627737	DLD1	viability	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-0.19005346462688055	[182]	[59,39,49]	-2	hSpCas9	negative selection	794710
66517189	66517212	16	+	26627737	DLD1	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-1.0188310727219703	[257]	[7,96,19]	-7	hSpCas9	negative selection	794711
66529041	66529064	16	-	26627737	DLD1	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.5511528194351196	[374]	[216,105,186]	5	hSpCas9	negative selection	794712
66531386	66531409	16	+	26627737	DLD1	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.3459888327908096	[1054]	[339,657,289]	3	hSpCas9	negative selection	794713
66536991	66537014	16	-	26627737	DLD1	viability	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.8531182174909377	[297]	[271,181,66]	8	hSpCas9	negative selection	794714
66513798	66513821	16	+	26627737	GBM cells	viability after 5 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	1.0027496858702256	[66]	[77,65]	9	hSpCas9	negative selection	877025
66517189	66517212	16	+	26627737	GBM cells	viability after 5 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.2748818094859372	[130]	[101,67]	4	hSpCas9	negative selection	877026
66529041	66529064	16	-	26627737	GBM cells	viability after 5 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.24031934427235163	[205]	[133,126]	4	hSpCas9	negative selection	877027
66531386	66531409	16	+	26627737	GBM cells	viability after 5 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.5159375848391403	[533]	[454,363]	7	hSpCas9	negative selection	877028
66536991	66537014	16	-	26627737	GBM cells	viability after 5 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	-0.4626182943528977	[396]	[192,115]	-6	hSpCas9	negative selection	877029
66513798	66513821	16	+	26627737	GBM cells	viability after 13 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	0.49010232431481504	[66]	[28,68]	6	hSpCas9	negative selection	959340
66517189	66517212	16	+	26627737	GBM cells	viability after 13 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.1136745803754623	[130]	[93,62]	1	hSpCas9	negative selection	959341
66529041	66529064	16	-	26627737	GBM cells	viability after 13 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.6095415784468217	[205]	[137,196]	7	hSpCas9	negative selection	959342
66531386	66531409	16	+	26627737	GBM cells	viability after 13 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.29919521413387073	[533]	[484,251]	4	hSpCas9	negative selection	959343
66536991	66537014	16	-	26627737	GBM cells	viability after 13 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	-0.07306881609116722	[396]	[292,132]	-1	hSpCas9	negative selection	959344
66513798	66513821	16	+	26627737	GBM cells	viability after 21 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	0.9960417522662743	[66]	[81,63]	8	hSpCas9	negative selection	1041655
66517189	66517212	16	+	26627737	GBM cells	viability after 21 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.7603646239677374	[130]	[130,110]	7	hSpCas9	negative selection	1041656
66529041	66529064	16	-	26627737	GBM cells	viability after 21 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.12906155069101066	[205]	[124,119]	1	hSpCas9	negative selection	1041657
66531386	66531409	16	+	26627737	GBM cells	viability after 21 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.04947771842231141	[533]	[329,272]	0	hSpCas9	negative selection	1041658
66536991	66537014	16	-	26627737	GBM cells	viability after 21 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	-0.37888172300521517	[396]	[168,162]	-3	hSpCas9	negative selection	1041659
66513798	66513821	16	+	26627737	RPE1	viability after 9 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-1.8178875652069977	[603]	[57,47]	-8	hSpCas9	negative selection	1123970
66517189	66517212	16	+	26627737	RPE1	viability after 9 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.6949784962170329	[218]	[30,56]	-5	hSpCas9	negative selection	1123971
66529041	66529064	16	-	26627737	RPE1	viability after 9 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.9328611424025935	[1202]	[181,216]	-6	hSpCas9	negative selection	1123972
66531386	66531409	16	+	26627737	RPE1	viability after 9 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.4916728889733666	[2073]	[867,970]	3	hSpCas9	negative selection	1123973
66536991	66537014	16	-	26627737	RPE1	viability after 9 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	1.1421186094391658	[481]	[291,385]	7	hSpCas9	negative selection	1123974
66513798	66513821	16	+	26627737	RPE1	viability after 12 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-1.9667573569640664	[603]	[41,40]	-8	hSpCas9	negative selection	1206285
66517189	66517212	16	+	26627737	RPE1	viability after 12 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.32058298143553476	[218]	[16,78]	-2	hSpCas9	negative selection	1206286
66529041	66529064	16	-	26627737	RPE1	viability after 12 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.729190601129615	[1202]	[193,195]	-5	hSpCas9	negative selection	1206287
66531386	66531409	16	+	26627737	RPE1	viability after 12 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.2513978763689697	[2073]	[689,634]	1	hSpCas9	negative selection	1206288
66536991	66537014	16	-	26627737	RPE1	viability after 12 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	1.215334591664099	[481]	[340,257]	7	hSpCas9	negative selection	1206289
66513798	66513821	16	+	26627737	RPE1	viability after 15 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-2.2422950021405743	[603]	[57,14]	-8	hSpCas9	negative selection	1288600
66517189	66517212	16	+	26627737	RPE1	viability after 15 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.7586601405624276	[218]	[1,69]	-5	hSpCas9	negative selection	1288601
66529041	66529064	16	-	26627737	RPE1	viability after 15 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-1.081032964513661	[1202]	[196,125]	-6	hSpCas9	negative selection	1288602
66531386	66531409	16	+	26627737	RPE1	viability after 15 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.4858561628814666	[2073]	[927,718]	3	hSpCas9	negative selection	1288603
66536991	66537014	16	-	26627737	RPE1	viability after 15 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	1.3285337879522099	[481]	[514,175]	7	hSpCas9	negative selection	1288604
66513798	66513821	16	+	26627737	RPE1	viability after 18 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-2.215941354683907	[603]	[22,47]	-8	hSpCas9	negative selection	1370915
66517189	66517212	16	+	26627737	RPE1	viability after 18 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.2831632278659695	[218]	[35,61]	-2	hSpCas9	negative selection	1370916
66529041	66529064	16	-	26627737	RPE1	viability after 18 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.6830526141277142	[1202]	[149,257]	-4	hSpCas9	negative selection	1370917
66531386	66531409	16	+	26627737	RPE1	viability after 18 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.6858796965577449	[2073]	[1042,747]	4	hSpCas9	negative selection	1370918
66536991	66537014	16	-	26627737	RPE1	viability after 18 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	1.03709067984683	[481]	[395,128]	6	hSpCas9	negative selection	1370919
66513798	66513821	16	+	26627737	HeLa	viability after 8 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	0.118047172388688	[165]	[131,36,77]	1	hSpCas9	negative selection	1453230
66517189	66517212	16	+	26627737	HeLa	viability after 8 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.09179551198681579	[259]	[71,162,77]	-1	hSpCas9	negative selection	1453231
66529041	66529064	16	-	26627737	HeLa	viability after 8 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.3475599340863921	[351]	[137,150,78]	-3	hSpCas9	negative selection	1453232
66531386	66531409	16	+	26627737	HeLa	viability after 8 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.5089939080002204	[1256]	[485,342,348]	-5	hSpCas9	negative selection	1453233
66536991	66537014	16	-	26627737	HeLa	viability after 8 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.12683382390832565	[570]	[204,377,219]	1	hSpCas9	negative selection	1453234
66513798	66513821	16	+	26627737	HeLa	viability after 12 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	0.5208706380793443	[165]	[116,77,102]	4	hSpCas9	negative selection	1535545
66517189	66517212	16	+	26627737	HeLa	viability after 12 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.25685233478681846	[259]	[173,132,78]	2	hSpCas9	negative selection	1535546
66529041	66529064	16	-	26627737	HeLa	viability after 12 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.07136683281853537	[351]	[82,201,121]	0	hSpCas9	negative selection	1535547
66531386	66531409	16	+	26627737	HeLa	viability after 12 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.11264647539393602	[1256]	[672,525,492]	1	hSpCas9	negative selection	1535548
66536991	66537014	16	-	26627737	HeLa	viability after 12 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	-0.4388702345742046	[570]	[81,320,100]	-4	hSpCas9	negative selection	1535549
66513798	66513821	16	+	26627737	HeLa	viability after 15 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-0.019504490177459033	[165]	[51,83,63]	0	hSpCas9	negative selection	1617860
66517189	66517212	16	+	26627737	HeLa	viability after 15 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.4590784290009673	[259]	[77,111,37]	-4	hSpCas9	negative selection	1617861
66529041	66529064	16	-	26627737	HeLa	viability after 15 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.5096143308962269	[351]	[116,56,129]	-4	hSpCas9	negative selection	1617862
66531386	66531409	16	+	26627737	HeLa	viability after 15 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.032763334854767345	[1256]	[652,292,630]	0	hSpCas9	negative selection	1617863
66536991	66537014	16	-	26627737	HeLa	viability after 15 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.12737858276049296	[570]	[169,372,216]	1	hSpCas9	negative selection	1617864
66513798	66513821	16	+	26627737	HeLa	viability after 18 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	0.061251919416002165	[165]	[41,69,63]	0	hSpCas9	negative selection	1700175
66517189	66517212	16	+	26627737	HeLa	viability after 18 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.5294120217228133	[259]	[48,87,37]	-5	hSpCas9	negative selection	1700176
66529041	66529064	16	-	26627737	HeLa	viability after 18 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.5085918455578422	[351]	[77,47,129]	-4	hSpCas9	negative selection	1700177
66531386	66531409	16	+	26627737	HeLa	viability after 18 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.02988272430821648	[1256]	[434,243,630]	0	hSpCas9	negative selection	1700178
66536991	66537014	16	-	26627737	HeLa	viability after 18 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.17182453101491946	[570]	[122,316,216]	1	hSpCas9	negative selection	1700179
66513798	66513821	16	+	26627737	HCT116	viability after 6 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	1.8722780781994968	[110]	[79,54]	8	hSpCas9	negative selection	1782490
66517189	66517212	16	+	26627737	HCT116	viability after 6 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.14235534312181775	[314]	[40,46]	-1	hSpCas9	negative selection	1782491
66529041	66529064	16	-	26627737	HCT116	viability after 6 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-1.1713480285335092	[613]	[96,12]	-6	hSpCas9	negative selection	1782492
66531386	66531409	16	+	26627737	HCT116	viability after 6 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.12290328912002524	[1943]	[629,87]	0	hSpCas9	negative selection	1782493
66536991	66537014	16	-	26627737	HCT116	viability after 6 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	1.4229522030197215	[412]	[438,27]	7	hSpCas9	negative selection	1782494
66513798	66513821	16	+	26627737	HCT116	viability after 8 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-0.8603618036698384	[134]	[45,34,41]	-8	hSpCas9	negative selection	1864805
66517189	66517212	16	+	26627737	HCT116	viability after 8 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	2.1958617676510555	[25]	[66,68,60]	9	hSpCas9	negative selection	1864806
66529041	66529064	16	-	26627737	HCT116	viability after 8 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.24040623094205932	[238]	[96,192,44]	-3	hSpCas9	negative selection	1864807
66531386	66531409	16	+	26627737	HCT116	viability after 8 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.20483512008537197	[888]	[427,411,434]	-2	hSpCas9	negative selection	1864808
66536991	66537014	16	-	26627737	HCT116	viability after 8 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.2954195364555505	[270]	[179,208,160]	3	hSpCas9	negative selection	1864809
66513798	66513821	16	+	26627737	HCT116	viability after 9 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	1.1968895137949207	[110]	[15,108]	7	hSpCas9	negative selection	1947120
66517189	66517212	16	+	26627737	HCT116	viability after 9 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.6820196186673326	[314]	[268,28]	5	hSpCas9	negative selection	1947121
66529041	66529064	16	-	26627737	HCT116	viability after 9 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.8039473875930049	[613]	[407,189]	6	hSpCas9	negative selection	1947122
66531386	66531409	16	+	26627737	HCT116	viability after 9 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.11672972471659815	[1943]	[945,259]	0	hSpCas9	negative selection	1947123
66536991	66537014	16	-	26627737	HCT116	viability after 9 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.8870348591151831	[412]	[151,244]	6	hSpCas9	negative selection	1947124
66513798	66513821	16	+	26627737	HCT116	viability after 12 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-0.8125476501651654	[134]	[18,78,25]	-7	hSpCas9	negative selection	2029435
66517189	66517212	16	+	26627737	HCT116	viability after 12 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	2.380148319071819	[25]	[51,67,94]	9	hSpCas9	negative selection	2029436
66529041	66529064	16	-	26627737	HCT116	viability after 12 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.044876762207430476	[238]	[172,133,77]	0	hSpCas9	negative selection	2029437
66531386	66531409	16	+	26627737	HCT116	viability after 12 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.3481047717165513	[888]	[708,717,349]	3	hSpCas9	negative selection	2029438
66536991	66537014	16	-	26627737	HCT116	viability after 12 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.5302403961284575	[270]	[229,168,214]	5	hSpCas9	negative selection	2029439
66513798	66513821	16	+	26627737	HCT116	viability after 15 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-2.850763818745317	[134]	[16,4,10]	-9	hSpCas9	negative selection	2111750
66517189	66517212	16	+	26627737	HCT116	viability after 15 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	3.2549744943803125	[25]	[59,165,190]	9	hSpCas9	negative selection	2111751
66529041	66529064	16	-	26627737	HCT116	viability after 15 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.06021206397286599	[238]	[197,177,60]	0	hSpCas9	negative selection	2111752
66531386	66531409	16	+	26627737	HCT116	viability after 15 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.1176641582746798	[888]	[470,657,284]	-1	hSpCas9	negative selection	2111753
66536991	66537014	16	-	26627737	HCT116	viability after 15 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	-0.3445775138697462	[270]	[147,116,105]	-4	hSpCas9	negative selection	2111754
66513798	66513821	16	+	26627737	HCT116	viability after 18 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-1.4763919698376906	[134]	[9,14,46]	-8	hSpCas9	negative selection	2194065
66517189	66517212	16	+	26627737	HCT116	viability after 18 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	1.7298232001728908	[25]	[28,38,57]	9	hSpCas9	negative selection	2194066
66529041	66529064	16	-	26627737	HCT116	viability after 18 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.536710158701134	[238]	[76,105,52]	-5	hSpCas9	negative selection	2194067
66531386	66531409	16	+	26627737	HCT116	viability after 18 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.26684425489647845	[888]	[404,702,426]	2	hSpCas9	negative selection	2194068
66536991	66537014	16	-	26627737	HCT116	viability after 18 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	-0.0687301486285131	[270]	[88,51,243]	0	hSpCas9	negative selection	2194069
66552389	66552412	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGGCGGGCTAACAGGGCGCTGG	TK2	ENSG00000166548	1.672452575183065	[7,6]	[3,5]	6	dCas9-VP64	positive selection	2411265
66552459	66552482	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTTATCGCGTAGCACATTAGCGG	TK2	ENSG00000166548	2.2581517002868963	[14,29]	[1,47]	7	dCas9-VP64	positive selection	2411266
66552365	66552388	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCTGGCCTGGCGTTAATGACGG	TK2	ENSG00000166548	-0.9386170380348293	[76,128]	[17,3]	-5	dCas9-VP64	positive selection	2411267
66519270	66519293	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATCGCTTGAACCTAG	TK2	ENSG00000166548	0.915813201608152	[93,47]	[29,27]	4	dCas9-VP64	positive selection	2442396
66514567	66514590	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCTGGCCGCCCATCGTCTAGG	TK2	ENSG00000166548	-0.0329650900813252	[388,64]	[87,4]	0	dCas9-VP64	positive selection	2468163
66543154	66543177	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAGCCACTGCACCCGGCCAAG	TK2	ENSG00000166548	1.1797326428655701	[26,26]	[14,10]	4	dCas9-VP64	positive selection	2469418
66552389	66552412	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGGCGGGCTAACAGGGCGCTGG	TK2	ENSG00000166548	1.5142513118443532	[47,29]	[51,21]	8	dCas9-VP64	positive selection	2506520
66552459	66552482	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTTATCGCGTAGCACATTAGCGG	TK2	ENSG00000166548	0.11802150784345206	[75,99]	[13,45]	1	dCas9-VP64	positive selection	2506521
66552365	66552388	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCTGGCCTGGCGTTAATGACGG	TK2	ENSG00000166548	-1.3261480134463264	[80,244]	[18,21]	-9	dCas9-VP64	positive selection	2506522
66519270	66519293	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATCGCTTGAACCTAG	TK2	ENSG00000166548	-0.3136691189391476	[37,20]	[8,5]	-3	dCas9-VP64	positive selection	2537651
66514567	66514590	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCTGGCCGCCCATCGTCTAGG	TK2	ENSG00000166548	-0.3398026399627511	[257,143]	[72,31]	-3	dCas9-VP64	positive selection	2563418
66543154	66543177	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAGCCACTGCACCCGGCCAAG	TK2	ENSG00000166548	0.8568341606696415	[42,16]	[22,11]	6	dCas9-VP64	positive selection	2564673
66517840	66517863	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTGGACTATGTAGTTCTGTCGG	TK2	ENSG00000166548	0.09212077363381876	[5,5]	[5,4]	2	hSpCas9	positive selection	3026935
66531437	66531460	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.3398397869969402	[2,2]	[1,3]	7	hSpCas9	positive selection	3026936
66531439	66531462	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACCACGATGCCTCTCGCTGGG	TK2	ENSG00000166548	-0.09002195416876502	[0,0]	[0,0]	-1	hSpCas9	positive selection	3026937
66531429	66531452	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	0.2091669400258882	[3,3]	[4,3]	4	hSpCas9	positive selection	3026938
66517840	66517863	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTGGACTATGTAGTTCTGTCGG	TK2	ENSG00000166548	-0.09934705507907804	[5,5]	[4,2]	-1	hSpCas9	positive selection	3094793
66531437	66531460	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	-0.24069519037582848	[2,2]	[1,0]	-4	hSpCas9	positive selection	3094794
66531439	66531462	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACCACGATGCCTCTCGCTGGG	TK2	ENSG00000166548	0.4833744715089985	[0,0]	[0,0]	8	hSpCas9	positive selection	3094795
66531429	66531452	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	0.1686839058562444	[3,3]	[3,2]	3	hSpCas9	positive selection	3094796
66531386	66531409		+	24336571	A375	resistance to PLX after 7 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.0956850463936636	[60,61]	[62,67]	3	hSpCas9	positive selection	3150416
66531440	66531463		-	24336571	A375	resistance to PLX after 7 days	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	-0.01625283977657732	[107,111]	[110,105]	0	hSpCas9	positive selection	3150417
66548998	66549021		-	24336571	A375	resistance to PLX after 7 days	TTCTTTTGTAGATAAAGAACAGG	TK2	ENSG00000166548	0.25514452091042095	[5,7]	[8,6]	7	hSpCas9	positive selection	3150418
66531386	66531409		+	24336571	A375	resistance to PLX after 14 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.6506556414620213	[68,64]	[51,46]	6	hSpCas9	positive selection	3208209
66531440	66531463		-	24336571	A375	resistance to PLX after 14 days	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	-0.00884299281951062	[111,112]	[50,52]	0	hSpCas9	positive selection	3208210
66548998	66549021		-	24336571	A375	resistance to PLX after 14 days	TTCTTTTGTAGATAAAGAACAGG	TK2	ENSG00000166548	-0.20196394624698266	[8,9]	[3,2]	-2	hSpCas9	positive selection	3208211
66531386	66531409		+	24336571	A375	viability after 7 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.42916481517272564	[47]	[60,61]	6	hSpCas9	negative selection	3266002
66531440	66531463		-	24336571	A375	viability after 7 days	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.3739549244657612	[88]	[107,111]	6	hSpCas9	negative selection	3266003
66548998	66549021		-	24336571	A375	viability after 7 days	TTCTTTTGTAGATAAAGAACAGG	TK2	ENSG00000166548	-1.0494160702119695	[15]	[5,7]	-9	hSpCas9	negative selection	3266004
66531386	66531409		+	24336571	A375	viability after 14 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.570737424071208	[47]	[68,64]	7	hSpCas9	negative selection	3323795
66531440	66531463		-	24336571	A375	viability after 14 days	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.42054147714946	[88]	[111,112]	5	hSpCas9	negative selection	3323796
66548998	66549021		-	24336571	A375	viability after 14 days	TTCTTTTGTAGATAAAGAACAGG	TK2	ENSG00000166548	-0.630178818988113	[15]	[8,9]	-6	hSpCas9	negative selection	3323797
66529053	66529076	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	-1.2583736268382073	[365,365]	[0,0]	-8	hSpCas9	positive selection	3397296
66531428	66531451	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	3.087401210003523	[17,17]	[0,0]	8	hSpCas9	positive selection	3397297
66528993	66529016	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	0.21293209208738176	[131,131]	[0,0]	1	hSpCas9	positive selection	3397298
66517840	66517863	16	-	26780180	HT29	viability (Avana library 4 designs)	AGTGGACTATGTAGTTCTGTCGG	TK2	ENSG00000166548	-0.389571784774504	[]	[]	-6	hSpCas9	negative selection	3465686
66531436	66531459	16	+	26780180	HT29	viability (Avana library 4 designs)	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.805415449801832	[]	[]	3	hSpCas9	negative selection	3465687
66531439	66531462	16	-	26780180	HT29	viability (Avana library 4 designs)	GTACCACGATGCCTCTCGCTGGG	TK2	ENSG00000166548	0.422591710435476	[]	[]	1	hSpCas9	negative selection	3465688
66531428	66531451	16	+	26780180	HT29	viability (Avana library 4 designs)	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	1.46150963192421	[]	[]	5	hSpCas9	negative selection	3465689
66517840	66517863	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGGACTATGTAGTTCTGTCGG	TK2	ENSG00000166548	0.275236833633625	[]	[]	0	hSpCas9	negative selection	3568995
66531428	66531451	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	3.98861907422894	[]	[]	6	hSpCas9	negative selection	3568996
66531436	66531459	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	2.62780837974675	[]	[]	4	hSpCas9	negative selection	3568997
66531439	66531462	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACCACGATGCCTCTCGCTGGG	TK2	ENSG00000166548	5.61158090498157	[]	[]	8	hSpCas9	negative selection	3568998
66531379	66531402	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACAGGCATACTCGTCCTCAGG	TK2	ENSG00000166548	3.21146968477897	[]	[]	5	hSpCas9	negative selection	3568999
66531375	66531398	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCATACTCGTCCTCAGGTAGG	TK2	ENSG00000166548	4.86657830423759	[]	[]	8	hSpCas9	negative selection	3569000
66517840	66517863	16	-	26780180	A375	viability (Avana lentiGuide)	AGTGGACTATGTAGTTCTGTCGG	TK2	ENSG00000166548	1.89858096652847	[]	[]	2	hSpCas9	negative selection	3677654
66531428	66531451	16	+	26780180	A375	viability (Avana lentiGuide)	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	3.98555021451724	[]	[]	4	hSpCas9	negative selection	3677655
66531436	66531459	16	+	26780180	A375	viability (Avana lentiGuide)	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	-0.787430979049406	[]	[]	-1	hSpCas9	negative selection	3677656
66531439	66531462	16	-	26780180	A375	viability (Avana lentiGuide)	GTACCACGATGCCTCTCGCTGGG	TK2	ENSG00000166548	0	[]	[]	0	hSpCas9	negative selection	3677657
66531379	66531402	16	-	26780180	A375	viability (Avana lentiGuide)	GGACAGGCATACTCGTCCTCAGG	TK2	ENSG00000166548	-3.54494129588467	[]	[]	-6	hSpCas9	negative selection	3677658
66531375	66531398	16	-	26780180	A375	viability (Avana lentiGuide)	AGGCATACTCGTCCTCAGGTAGG	TK2	ENSG00000166548	4.58274363334378	[]	[]	4	hSpCas9	negative selection	3677659
66517840	66517863	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGGACTATGTAGTTCTGTCGG	TK2	ENSG00000166548	0.0406715475128937	[7]	[7,6]	1	hSpCas9	positive selection	3786261
66531428	66531451	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	0.3349203183006727	[4]	[6,5]	8	hSpCas9	positive selection	3786262
66531436	66531459	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.1157129357403596	[3]	[4,3]	3	hSpCas9	positive selection	3786263
66531439	66531462	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACCACGATGCCTCTCGCTGGG	TK2	ENSG00000166548	0.29974851593252194	[3]	[4,4]	8	hSpCas9	positive selection	3786264
66531379	66531402	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACAGGCATACTCGTCCTCAGG	TK2	ENSG00000166548	0.3945190060638032	[4]	[5,5]	9	hSpCas9	positive selection	3786265
66531375	66531398	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCATACTCGTCCTCAGGTAGG	TK2	ENSG00000166548	0.3167212793972985	[4]	[6,5]	8	hSpCas9	positive selection	3786266
66517840	66517863	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGGACTATGTAGTTCTGTCGG	TK2	ENSG00000166548	0.1895104710195466	[7]	[6,7]	4	hSpCas9	positive selection	3894868
66531428	66531451	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.28198321765618384	[5]	[4,3]	-4	hSpCas9	positive selection	3894869
66531436	66531459	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.023415622456339824	[4]	[4,2]	0	hSpCas9	positive selection	3894870
66531439	66531462	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACCACGATGCCTCTCGCTGGG	TK2	ENSG00000166548	0.8182022979086288	[0]	[0,0]	9	hSpCas9	positive selection	3894871
66531379	66531402	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACAGGCATACTCGTCCTCAGG	TK2	ENSG00000166548	-0.12523115522911404	[5]	[2,4]	-2	hSpCas9	positive selection	3894872
66531375	66531398	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCATACTCGTCCTCAGGTAGG	TK2	ENSG00000166548	-0.27662873383134706	[5]	[1,4]	-4	hSpCas9	positive selection	3894873
66528983	66529006	16	+	26780180	A375	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	1.0618896062203	[]	[]	5	hSpCas9	negative selection	4004216
66531386	66531409	16	+	26780180	A375	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	1.68923168428729	[]	[]	9	hSpCas9	negative selection	4004217
66531428	66531451	16	+	26780180	A375	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	0.821766910130846	[]	[]	3	hSpCas9	negative selection	4004218
66529053	66529076	16	-	26780180	A375	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	1.30944782190888	[]	[]	7	hSpCas9	negative selection	4004219
66531440	66531463	16	-	26780180	A375	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.469023754061902	[]	[]	1	hSpCas9	negative selection	4004220
66528993	66529016	16	-	26780180	A375	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	1.12261204579121	[]	[]	5	hSpCas9	negative selection	4004221
66528983	66529006	16	+	26780180	HT29	viability (GeCKOv2 library)	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.359799500460754	[]	[]	1	hSpCas9	negative selection	4112182
66531386	66531409	16	+	26780180	HT29	viability (GeCKOv2 library)	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	2.20442566906447	[]	[]	9	hSpCas9	negative selection	4112183
66531428	66531451	16	+	26780180	HT29	viability (GeCKOv2 library)	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	1.25967646332125	[]	[]	6	hSpCas9	negative selection	4112184
66529053	66529076	16	-	26780180	HT29	viability (GeCKOv2 library)	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.692498834908634	[]	[]	2	hSpCas9	negative selection	4112185
66531440	66531463	16	-	26780180	HT29	viability (GeCKOv2 library)	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.715114467096338	[]	[]	2	hSpCas9	negative selection	4112186
66528993	66529016	16	-	26780180	HT29	viability (GeCKOv2 library)	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	1.40241886676613	[]	[]	7	hSpCas9	negative selection	4112187
66531386	66531409	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.31289410055549016	[5]	[4,5]	7	hSpCas9	positive selection	4176817
66531440	66531463	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.3380290373019367	[6]	[5,5]	7	hSpCas9	positive selection	4176818
66548998	66549021	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCTTTTGTAGATAAAGAACAGG	TK2	ENSG00000166548	-0.04469943629447953	[2]	[1,1]	-1	hSpCas9	positive selection	4176819
66531386	66531409	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.8516070467952601	[5]	[3,3,4,4]	5	hSpCas9	positive selection	4240839
66531440	66531463	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.7149299445299121	[6]	[4,5,4,3]	4	hSpCas9	positive selection	4240840
66548998	66549021	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCTTTTGTAGATAAAGAACAGG	TK2	ENSG00000166548	-0.035415701011358214	[3]	[1,0,2,0]	0	hSpCas9	positive selection	4240841
66531440	66531463	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	-0.1410451663228317	[4]	[4,1]	-3	hSpCas9	positive selection	4303204
66528983	66529006	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.06163302556527567	[3]	[3,1]	-1	hSpCas9	positive selection	4303205
66531386	66531409	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.8503745341481493	[2]	[0,0]	-9	hSpCas9	positive selection	4303206
66529053	66529076	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.18010814325789262	[3]	[3,2]	3	hSpCas9	positive selection	4367457
66531428	66531451	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.6717062770443373	[1]	[0,0]	-9	hSpCas9	positive selection	4367458
66528993	66529016	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	0.09942332940062687	[3]	[3,1]	2	hSpCas9	positive selection	4367459
66517190	66517212	16	+	27760321	OCIAML3	viability	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.5209727606891749	[747,635]	[786,756]	6	hSpCas9	negative selection	4447148
66517810	66517832	16	-	27760321	OCIAML3	viability	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	0.06566702326688491	[486,386]	[315,406]	0	hSpCas9	negative selection	4447149
66517835	66517857	16	-	27760321	OCIAML3	viability	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.7914225647650712	[453,314]	[169,173]	-6	hSpCas9	negative selection	4447150
66528984	66529006	16	+	27760321	OCIAML3	viability	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.4594469134943715	[16,13]	[3,14]	-5	hSpCas9	negative selection	4447151
66529053	66529075	16	+	27760321	OCIAML3	viability	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	-0.05401793584339987	[163,149]	[43,214]	0	hSpCas9	negative selection	4447152
66517190	66517212	16	+	27760321	OCIAML2	viability	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.3132151193315442	[747,635]	[621,786]	4	hSpCas9	negative selection	4530611
66517810	66517832	16	-	27760321	OCIAML2	viability	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	0.11271327252498195	[486,386]	[309,471]	1	hSpCas9	negative selection	4530612
66517835	66517857	16	-	27760321	OCIAML2	viability	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.1327151049350221	[453,314]	[279,280]	-2	hSpCas9	negative selection	4530613
66528984	66529006	16	+	27760321	OCIAML2	viability	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-3.6416031813270635	[16,13]	[0,0]	-9	hSpCas9	negative selection	4530614
66529053	66529075	16	+	27760321	OCIAML2	viability	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	-0.37883801231077907	[163,149]	[66,137]	-4	hSpCas9	negative selection	4530615
66517190	66517212	16	+	27760321	MV411	viability	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.47962761628350414	[747,635]	[403,980]	3	hSpCas9	negative selection	4614074
66517810	66517832	16	-	27760321	MV411	viability	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	-0.2773411702837012	[486,386]	[102,436]	-2	hSpCas9	negative selection	4614075
66517835	66517857	16	-	27760321	MV411	viability	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.8252390014413751	[453,314]	[79,233]	-5	hSpCas9	negative selection	4614076
66528984	66529006	16	+	27760321	MV411	viability	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-3.347779247147333	[16,13]	[0,0]	-9	hSpCas9	negative selection	4614077
66529053	66529075	16	+	27760321	MV411	viability	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	0.28752482507903543	[163,149]	[133,114]	2	hSpCas9	negative selection	4614078
66517190	66517212	16	+	27760321	HL60	viability	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.7360380203326032	[747,635]	[734,1153]	8	hSpCas9	negative selection	4697537
66517810	66517832	16	-	27760321	HL60	viability	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	0.4447999560083952	[486,386]	[529,432]	5	hSpCas9	negative selection	4697538
66517835	66517857	16	-	27760321	HL60	viability	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.5144634296314918	[453,314]	[211,222]	-5	hSpCas9	negative selection	4697539
66528984	66529006	16	+	27760321	HL60	viability	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.7557995297678879	[16,13]	[13,28]	8	hSpCas9	negative selection	4697540
66529053	66529075	16	+	27760321	HL60	viability	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	-0.9492131256928227	[163,149]	[62,69]	-7	hSpCas9	negative selection	4697541
66517190	66517212	16	+	27760321	HT1080	viability	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	3.1980170778343235	[635,495]	[2260,1858]	9	hSpCas9	negative selection	4781000
66517810	66517832	16	-	27760321	HT1080	viability	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	-2.025690715696727	[386,301]	[37,28]	-6	hSpCas9	negative selection	4781001
66517835	66517857	16	-	27760321	HT1080	viability	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	0.583246063480048	[314,245]	[91,249]	3	hSpCas9	negative selection	4781002
66528984	66529006	16	+	27760321	HT1080	viability	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-2.316638003739512	[13,10]	[0,0]	-6	hSpCas9	negative selection	4781003
66529053	66529075	16	+	27760321	HT1080	viability	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	-0.4769829957910865	[149,116]	[10,67]	-2	hSpCas9	negative selection	4781004
66517190	66517212	16	+	27760321	HT29	viability after 7 days	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.2242385017883043	[635,495]	[1011,868,695]	3	hSpCas9	negative selection	4864463
66517810	66517832	16	-	27760321	HT29	viability after 7 days	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	0.10673941155773439	[386,301]	[552,284,598]	1	hSpCas9	negative selection	4864464
66517835	66517857	16	-	27760321	HT29	viability after 7 days	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.5458140322086247	[314,245]	[338,297,120]	-7	hSpCas9	negative selection	4864465
66528984	66529006	16	+	27760321	HT29	viability after 7 days	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.3472142003454035	[13,10]	[0,14,19]	-5	hSpCas9	negative selection	4864466
66529053	66529075	16	+	27760321	HT29	viability after 7 days	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	0.38849044909405506	[149,116]	[165,263,234]	6	hSpCas9	negative selection	4864467
66517190	66517212	16	+	27760321	HT29	viability after 25 days	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.6360402329421216	[635,495]	[984,1061,963]	7	hSpCas9	negative selection	4947926
66517810	66517832	16	-	27760321	HT29	viability after 25 days	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	0.2843295265320887	[386,301]	[613,233,592]	3	hSpCas9	negative selection	4947927
66517835	66517857	16	-	27760321	HT29	viability after 25 days	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.28683820786058617	[314,245]	[179,273,347]	-3	hSpCas9	negative selection	4947928
66528984	66529006	16	+	27760321	HT29	viability after 25 days	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-1.821408717479735	[13,10]	[0,9,0]	-8	hSpCas9	negative selection	4947929
66529053	66529075	16	+	27760321	HT29	viability after 25 days	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	0.3960611551787039	[149,116]	[261,187,141]	4	hSpCas9	negative selection	4947930
66517190	66517212	16	+	27760321	HT29	viability after 22 days	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.2531087141285514	[635,495]	[728,794,816]	2	hSpCas9	negative selection	5031389
66517810	66517832	16	-	27760321	HT29	viability after 22 days	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	0.27496889117796636	[386,301]	[540,317,585]	3	hSpCas9	negative selection	5031390
66517835	66517857	16	-	27760321	HT29	viability after 22 days	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.16933929076190352	[314,245]	[233,298,333]	-2	hSpCas9	negative selection	5031391
66528984	66529006	16	+	27760321	HT29	viability after 22 days	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.056049763620380944	[13,10]	[0,33,6]	0	hSpCas9	negative selection	5031392
66529053	66529075	16	+	27760321	HT29	viability after 22 days	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	0.45605345421198873	[149,116]	[264,225,141]	5	hSpCas9	negative selection	5031393
66517190	66517212	16	+	27760321	HT29	viability after 19 days	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.6654630415864647	[635,495]	[769,1539,752]	6	hSpCas9	negative selection	5114852
66517810	66517832	16	-	27760321	HT29	viability after 19 days	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	-0.17173472933164502	[386,301]	[365,286,395]	-1	hSpCas9	negative selection	5114853
66517835	66517857	16	-	27760321	HT29	viability after 19 days	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.16217980059180598	[314,245]	[49,65,702]	-1	hSpCas9	negative selection	5114854
66528984	66529006	16	+	27760321	HT29	viability after 19 days	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-3.837798848022082	[13,10]	[0,0,0]	-9	hSpCas9	negative selection	5114855
66529053	66529075	16	+	27760321	HT29	viability after 19 days	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	0.6584042525529041	[149,116]	[392,327,25]	6	hSpCas9	negative selection	5114856
66517190	66517212	16	+	27760321	HT29	viability after 16 days	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.36955001857506853	[635,495]	[816,511,1132]	4	hSpCas9	negative selection	5198315
66517810	66517832	16	-	27760321	HT29	viability after 16 days	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	0.1777270725569878	[386,301]	[500,356,457]	2	hSpCas9	negative selection	5198316
66517835	66517857	16	-	27760321	HT29	viability after 16 days	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.5553167586761789	[314,245]	[217,216,205]	-5	hSpCas9	negative selection	5198317
66528984	66529006	16	+	27760321	HT29	viability after 16 days	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.2827264870680892	[13,10]	[0,30,0]	-3	hSpCas9	negative selection	5198318
66529053	66529075	16	+	27760321	HT29	viability after 16 days	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	0.6010757765247563	[149,116]	[230,265,181]	7	hSpCas9	negative selection	5198319
66517190	66517212	16	+	27760321	HT29	viability after 13 days	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.18775860141576783	[635,495]	[659,705,869]	2	hSpCas9	negative selection	5281778
66517810	66517832	16	-	27760321	HT29	viability after 13 days	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	-0.3826296214626641	[386,301]	[205,307,399]	-4	hSpCas9	negative selection	5281779
66517835	66517857	16	-	27760321	HT29	viability after 13 days	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.367602917481807	[314,245]	[180,292,280]	-4	hSpCas9	negative selection	5281780
66528984	66529006	16	+	27760321	HT29	viability after 13 days	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.936341076015613	[13,10]	[18,0,2]	-7	hSpCas9	negative selection	5281781
66529053	66529075	16	+	27760321	HT29	viability after 13 days	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	0.34569127356729124	[149,116]	[393,85,114]	4	hSpCas9	negative selection	5281782
66517190	66517212	16	+	27760321	HT29	viability after 10 days	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.2357410182835945	[635,495]	[698,828,964]	3	hSpCas9	negative selection	5365241
66517810	66517832	16	-	27760321	HT29	viability after 10 days	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	0.22905530085674286	[386,301]	[512,593,409]	3	hSpCas9	negative selection	5365242
66517835	66517857	16	-	27760321	HT29	viability after 10 days	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.6942767189376262	[314,245]	[146,160,336]	-7	hSpCas9	negative selection	5365243
66528984	66529006	16	+	27760321	HT29	viability after 10 days	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.9921463815850124	[13,10]	[0,19,2]	-8	hSpCas9	negative selection	5365244
66529053	66529075	16	+	27760321	HT29	viability after 10 days	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	0.7396156016426595	[149,116]	[373,157,298]	8	hSpCas9	negative selection	5365245
66517190	66517212	16	+	27760321	MOLM13	viability	AGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.3549155649148391	[747,635]	[636,378]	2	hSpCas9	negative selection	5448704
66517810	66517832	16	-	27760321	MOLM13	viability	GACTGGATCTTGAGGAACATGG	TK2	ENSG00000166548	-1.8915555170287615	[486,386]	[51,77]	-8	hSpCas9	negative selection	5448705
66517835	66517857	16	-	27760321	MOLM13	viability	CTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	0.3617901728959225	[453,314]	[469,109]	2	hSpCas9	negative selection	5448706
66528984	66529006	16	+	27760321	MOLM13	viability	ACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-3.1217224343197376	[16,13]	[0,0]	-9	hSpCas9	negative selection	5448707
66529053	66529075	16	+	27760321	MOLM13	viability	CCGTACAGATGACACCTAAAGG	TK2	ENSG00000166548	-0.6225506282543991	[163,149]	[16,91]	-4	hSpCas9	negative selection	5448708
66531440	66531463	16	-	27260156	BXPC3	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.052106073033213685	[1341]	[1208,1291,1611,1774]	1	hSpCas9	negative selection	5575664
66528983	66529006	16	+	27260156	BXPC3	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.0701739715947064	[759]	[697,627,816,913]	-2	hSpCas9	negative selection	5575665
66531386	66531409	16	+	27260156	BXPC3	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.12686723254249505	[321]	[332,255,459,439]	3	hSpCas9	negative selection	5575666
66529053	66529076	16	-	27260156	BXPC3	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.41133252450885727	[670]	[727,896,1121,1016]	8	hSpCas9	negative selection	5639917
66531428	66531451	16	+	27260156	BXPC3	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.43096038197910813	[70]	[40,78,75,19]	-7	hSpCas9	negative selection	5639918
66528993	66529016	16	-	27260156	BXPC3	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.5625903513956895	[502]	[325,326,352,429]	-8	hSpCas9	negative selection	5639919
66531440	66531463	16	-	27260156	A673	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.10387453523905821	[1341]	[1707,1597,1601,2033]	2	hSpCas9	negative selection	5696915
66528983	66529006	16	+	27260156	A673	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.11162300909820944	[759]	[962,681,920,826]	-3	hSpCas9	negative selection	5696916
66531386	66531409	16	+	27260156	A673	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.27325775564351173	[321]	[359,213,271,447]	-6	hSpCas9	negative selection	5696917
66529053	66529076	16	-	27260156	A673	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.2945087811593172	[670]	[1183,913,992,877]	7	hSpCas9	negative selection	5761168
66531428	66531451	16	+	27260156	A673	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-1.6558398235476797	[70]	[18,36,23,26]	-9	hSpCas9	negative selection	5761169
66528993	66529016	16	-	27260156	A673	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.13032953516277052	[502]	[606,564,600,431]	-3	hSpCas9	negative selection	5761170
66531440	66531463	16	-	27260156	A375	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.23222268425133397	[1341]	[1856,2432,1604,1576]	3	hSpCas9	negative selection	5818166
66528983	66529006	16	+	27260156	A375	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.304893922214568	[759]	[1106,842,1181,1201]	4	hSpCas9	negative selection	5818167
66531386	66531409	16	+	27260156	A375	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.19617669298342244	[321]	[648,420,340,323]	3	hSpCas9	negative selection	5818168
66529053	66529076	16	-	27260156	A375	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.4758380167906604	[670]	[852,1382,1109,1052]	7	hSpCas9	negative selection	5882419
66531428	66531451	16	+	27260156	A375	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.3762040239243092	[70]	[80,60,57,55]	-5	hSpCas9	negative selection	5882420
66528993	66529016	16	-	27260156	A375	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.1179317124817796	[502]	[705,490,625,356]	-2	hSpCas9	negative selection	5882421
66531440	66531463	16	-	27260156	COLO741	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.08930369988380726	[1341]	[1932,1769,1777]	2	hSpCas9	negative selection	5939417
66528983	66529006	16	+	27260156	COLO741	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.06407261183467428	[759]	[992,911,887]	-1	hSpCas9	negative selection	5939418
66531386	66531409	16	+	27260156	COLO741	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.026305689832359147	[321]	[670,313,300]	0	hSpCas9	negative selection	5939419
66529053	66529076	16	-	27260156	COLO741	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.7310081369799676	[670]	[1465,1541,1272]	9	hSpCas9	negative selection	6003670
66531428	66531451	16	+	27260156	COLO741	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.665886594135439	[70]	[49,107,15]	-8	hSpCas9	negative selection	6003671
66528993	66529016	16	-	27260156	COLO741	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	0.07227641325472743	[502]	[818,647,577]	1	hSpCas9	negative selection	6003672
66531440	66531463	16	-	27260156	CAL120	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.10747414883438533	[1341]	[1820,1560,2013]	1	hSpCas9	negative selection	6060668
66528983	66529006	16	+	27260156	CAL120	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.05738041313736342	[759]	[1333,878,794]	0	hSpCas9	negative selection	6060669
66531386	66531409	16	+	27260156	CAL120	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.5829860859499185	[321]	[815,535,482]	8	hSpCas9	negative selection	6060670
66529053	66529076	16	-	27260156	CAL120	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.8826899851663031	[670]	[2303,1334,1101]	9	hSpCas9	negative selection	6124921
66531428	66531451	16	+	27260156	CAL120	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.4591290088245765	[70]	[23,113,48]	-6	hSpCas9	negative selection	6124922
66528993	66529016	16	-	27260156	CAL120	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.2298203197638352	[502]	[533,584,482]	-3	hSpCas9	negative selection	6124923
66531440	66531463	16	-	27260156	CADOES1	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.048845072235135456	[1341]	[1198,1410,1262,1291]	0	hSpCas9	negative selection	6181919
66528983	66529006	16	+	27260156	CADOES1	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.0216934184767118	[759]	[692,748,552,793]	0	hSpCas9	negative selection	6181920
66531386	66531409	16	+	27260156	CADOES1	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.4016723015943571	[321]	[428,420,246,488]	6	hSpCas9	negative selection	6181921
66529053	66529076	16	-	27260156	CADOES1	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.5429164674250125	[670]	[860,807,949,1021]	8	hSpCas9	negative selection	6246172
66531428	66531451	16	+	27260156	CADOES1	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.9324767114184227	[70]	[48,17,44,25]	-9	hSpCas9	negative selection	6246173
66528993	66529016	16	-	27260156	CADOES1	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.3882935536722238	[502]	[413,414,337,258]	-6	hSpCas9	negative selection	6246174
66531440	66531463	16	-	27260156	EWS502	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.04940742982937185	[1341]	[1344,1353,1421,1799]	0	hSpCas9	negative selection	6303170
66528983	66529006	16	+	27260156	EWS502	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.010655054946686615	[759]	[994,604,891,729]	0	hSpCas9	negative selection	6303171
66531386	66531409	16	+	27260156	EWS502	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.2387445100595998	[321]	[445,537,282,322]	4	hSpCas9	negative selection	6303172
66529053	66529076	16	-	27260156	EWS502	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.6774641436707939	[670]	[1134,1031,1198,1184]	9	hSpCas9	negative selection	6367423
66531428	66531451	16	+	27260156	EWS502	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.3234109134792291	[70]	[102,62,41,23]	-5	hSpCas9	negative selection	6367424
66528993	66529016	16	-	27260156	EWS502	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.34089321528256117	[502]	[433,281,369,611]	-5	hSpCas9	negative selection	6367425
66531440	66531463	16	-	27260156	EW8	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.21991154268110935	[1341]	[1498,1359,875,1419]	4	hSpCas9	negative selection	6424421
66528983	66529006	16	+	27260156	EW8	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.03155166010034682	[759]	[530,595,652,720]	0	hSpCas9	negative selection	6424422
66531386	66531409	16	+	27260156	EW8	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.2681568200495428	[321]	[193,149,246,266]	-5	hSpCas9	negative selection	6424423
66529053	66529076	16	-	27260156	EW8	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.27979473387375997	[670]	[706,650,623,667]	5	hSpCas9	negative selection	6488674
66531428	66531451	16	+	27260156	EW8	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.7427632911303412	[70]	[11,101,18,4]	-8	hSpCas9	negative selection	6488675
66528993	66529016	16	-	27260156	EW8	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.3803753253771495	[502]	[297,413,221,331]	-6	hSpCas9	negative selection	6488676
66531440	66531463	16	-	27260156	CORL105	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.13413581669544183	[1341]	[1669,1749,1683,1782]	2	hSpCas9	negative selection	6545672
66528983	66529006	16	+	27260156	CORL105	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.0030878487371763796	[759]	[919,780,1097,802]	0	hSpCas9	negative selection	6545673
66531386	66531409	16	+	27260156	CORL105	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.28170478964064893	[321]	[405,403,647,403]	5	hSpCas9	negative selection	6545674
66529053	66529076	16	-	27260156	CORL105	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.49854720457547896	[670]	[1281,1039,1106,1016]	8	hSpCas9	negative selection	6609925
66531428	66531451	16	+	27260156	CORL105	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.8596372262707392	[70]	[48,19,84,35]	-9	hSpCas9	negative selection	6609926
66528993	66529016	16	-	27260156	CORL105	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.3011529390099311	[502]	[506,486,699,253]	-5	hSpCas9	negative selection	6609927
66531440	66531463	16	-	27260156	HS294T	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.43081681001232996	[1341]	[624,761,631,797]	6	hSpCas9	negative selection	6666923
66528983	66529006	16	+	27260156	HS294T	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.1531589722740414	[759]	[271,278,243,258]	-2	hSpCas9	negative selection	6666924
66531386	66531409	16	+	27260156	HS294T	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.3057432391721514	[321]	[90,120,212,205]	4	hSpCas9	negative selection	6666925
66529053	66529076	16	-	27260156	HS294T	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.04501540912638469	[670]	[248,290,231,304]	0	hSpCas9	negative selection	6731176
66531428	66531451	16	+	27260156	HS294T	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	1.0396176781773954	[70]	[66,15,95,44]	9	hSpCas9	negative selection	6731177
66528993	66529016	16	-	27260156	HS294T	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	0.20420981405089866	[502]	[194,314,151,234]	2	hSpCas9	negative selection	6731178
66531440	66531463	16	-	27260156	HCC44	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.15243272425085297	[1341]	[1720,1436,1988,1677]	2	hSpCas9	negative selection	6788174
66528983	66529006	16	+	27260156	HCC44	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.09920076777584019	[759]	[883,746,1037,596]	-2	hSpCas9	negative selection	6788175
66531386	66531409	16	+	27260156	HCC44	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.20376952200126686	[321]	[488,348,287,537]	3	hSpCas9	negative selection	6788176
66529053	66529076	16	-	27260156	HCC44	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.33663465298347073	[670]	[1137,874,856,965]	5	hSpCas9	negative selection	6852427
66531428	66531451	16	+	27260156	HCC44	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.2958918452479402	[70]	[125,9,88,53]	-5	hSpCas9	negative selection	6852428
66528993	66529016	16	-	27260156	HCC44	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.12287229152831913	[502]	[714,522,382,459]	-2	hSpCas9	negative selection	6852429
66531440	66531463	16	-	27260156	G402	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	-0.06990521784422565	[1341]	[1683,1164,2262,1137]	-1	hSpCas9	negative selection	6909425
66528983	66529006	16	+	27260156	G402	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.10002618831462773	[759]	[926,1141,641,775]	-1	hSpCas9	negative selection	6909426
66531386	66531409	16	+	27260156	G402	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.4754153502673504	[321]	[424,1109,430,246]	6	hSpCas9	negative selection	6909427
66529053	66529076	16	-	27260156	G402	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.6172268197340357	[670]	[1559,1455,1431,655]	7	hSpCas9	negative selection	6973678
66531428	66531451	16	+	27260156	G402	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	0.4235297339497368	[70]	[193,10,53,205]	5	hSpCas9	negative selection	6973679
66528993	66529016	16	-	27260156	G402	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.40006515862308595	[502]	[755,345,373,419]	-5	hSpCas9	negative selection	6973680
66531440	66531463	16	-	27260156	L33	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.1820868151898558	[1341]	[1423,691,964,1444]	4	hSpCas9	negative selection	7030676
66528983	66529006	16	+	27260156	L33	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.023335162839637658	[759]	[802,272,551,741]	0	hSpCas9	negative selection	7030677
66531386	66531409	16	+	27260156	L33	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.24938466132130016	[321]	[402,181,206,353]	5	hSpCas9	negative selection	7030678
66529053	66529076	16	-	27260156	L33	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.4306343155112208	[670]	[723,408,701,784]	8	hSpCas9	negative selection	7094929
66531428	66531451	16	+	27260156	L33	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.6671589277411596	[70]	[24,15,56,24]	-9	hSpCas9	negative selection	7094930
66528993	66529016	16	-	27260156	L33	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.13166546471676627	[502]	[530,194,300,349]	-3	hSpCas9	negative selection	7094931
66531440	66531463	16	-	27260156	K562	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.32351668847828274	[1341]	[1776,1468,1276,1457]	4	hSpCas9	negative selection	7151927
66528983	66529006	16	+	27260156	K562	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.2798984368461602	[759]	[781,868,843,780]	3	hSpCas9	negative selection	7151928
66531386	66531409	16	+	27260156	K562	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.22879626579892226	[321]	[254,426,391,269]	3	hSpCas9	negative selection	7151929
66529053	66529076	16	-	27260156	K562	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.9199274610242377	[670]	[1158,713,1636,988]	9	hSpCas9	negative selection	7216180
66531428	66531451	16	+	27260156	K562	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.06555675097821734	[70]	[28,80,114,18]	-1	hSpCas9	negative selection	7216181
66528993	66529016	16	-	27260156	K562	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	0.3411290802048694	[502]	[527,819,481,452]	4	hSpCas9	negative selection	7216182
66531440	66531463	16	-	27260156	HT29	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.10633366470719197	[1341]	[1963,1866,1896,1358]	2	hSpCas9	negative selection	7273178
66528983	66529006	16	+	27260156	HT29	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.047182486337187246	[759]	[947,1015,1007,643]	-1	hSpCas9	negative selection	7273179
66531386	66531409	16	+	27260156	HT29	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.1114419802733157	[321]	[440,370,375,488]	2	hSpCas9	negative selection	7273180
66529053	66529076	16	-	27260156	HT29	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.5656988904905439	[670]	[1554,1367,1099,878]	9	hSpCas9	negative selection	7337431
66531428	66531451	16	+	27260156	HT29	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.5830882896771064	[70]	[92,47,24,64]	-7	hSpCas9	negative selection	7337432
66528993	66529016	16	-	27260156	HT29	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.06814612943479872	[502]	[713,665,383,581]	-1	hSpCas9	negative selection	7337433
66531440	66531463	16	-	27260156	MHHES1	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.11924399306304667	[1341]	[1599,2203,1505,1340]	2	hSpCas9	negative selection	7394429
66528983	66529006	16	+	27260156	MHHES1	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.22346685487014895	[759]	[1019,1280,964,788]	4	hSpCas9	negative selection	7394430
66531386	66531409	16	+	27260156	MHHES1	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.8037806158319092	[321]	[184,260,171,209]	-9	hSpCas9	negative selection	7394431
66529053	66529076	16	-	27260156	MHHES1	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.5341006653318204	[670]	[862,1405,881,1181]	8	hSpCas9	negative selection	7458682
66531428	66531451	16	+	27260156	MHHES1	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.1816782527469143	[70]	[11,21,118,106]	-3	hSpCas9	negative selection	7458683
66528993	66529016	16	-	27260156	MHHES1	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.04908071665447816	[502]	[435,765,610,406]	-1	hSpCas9	negative selection	7458684
66531440	66531463	16	-	27260156	MEWO	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	-0.04488998398230737	[1341]	[1377,1234,1068]	-1	hSpCas9	negative selection	7515680
66528983	66529006	16	+	27260156	MEWO	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.1552471016647431	[759]	[600,649,656]	-3	hSpCas9	negative selection	7515681
66531386	66531409	16	+	27260156	MEWO	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.5587494124995145	[321]	[232,208,176]	-8	hSpCas9	negative selection	7515682
66529053	66529076	16	-	27260156	MEWO	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.28404705106664785	[670]	[1011,744,583]	6	hSpCas9	negative selection	7579933
66531428	66531451	16	+	27260156	MEWO	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.19327211890419527	[70]	[71,51,52]	-4	hSpCas9	negative selection	7579934
66528993	66529016	16	-	27260156	MEWO	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.18501297612737055	[502]	[495,341,419]	-4	hSpCas9	negative selection	7579935
66531440	66531463	16	-	27260156	LNCAPCLONEFGC	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	-0.019748833112437802	[1341]	[1543,897,1192,1172]	0	hSpCas9	negative selection	7636931
66528983	66529006	16	+	27260156	LNCAPCLONEFGC	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.2180077116269281	[759]	[710,746,990,786]	3	hSpCas9	negative selection	7636932
66531386	66531409	16	+	27260156	LNCAPCLONEFGC	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.2052883968714861	[321]	[247,221,435,462]	3	hSpCas9	negative selection	7636933
66529053	66529076	16	-	27260156	LNCAPCLONEFGC	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.7872642272714904	[670]	[1202,923,1058,1015]	9	hSpCas9	negative selection	7701184
66531428	66531451	16	+	27260156	LNCAPCLONEFGC	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	0.27227875644786437	[70]	[90,133,52,24]	4	hSpCas9	negative selection	7701185
66528993	66529016	16	-	27260156	LNCAPCLONEFGC	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.3662048713591576	[502]	[275,341,413,392]	-5	hSpCas9	negative selection	7701186
66531440	66531463	16	-	27260156	PANC0327	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.25346761890893577	[1341]	[1797,1060,1747,1154]	4	hSpCas9	negative selection	7758182
66528983	66529006	16	+	27260156	PANC0327	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.17425338774395693	[759]	[614,424,743,632]	-3	hSpCas9	negative selection	7758183
66531386	66531409	16	+	27260156	PANC0327	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.5650479384407449	[321]	[373,405,550,359]	8	hSpCas9	negative selection	7758184
66529053	66529076	16	-	27260156	PANC0327	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.4653864865457987	[670]	[1305,676,717,648]	7	hSpCas9	negative selection	7822435
66531428	66531451	16	+	27260156	PANC0327	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-1.888398675295901	[70]	[8,20,31,4]	-9	hSpCas9	negative selection	7822436
66528993	66529016	16	-	27260156	PANC0327	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.1973166963517472	[502]	[480,214,534,357]	-3	hSpCas9	negative selection	7822437
66531440	66531463	16	-	27260156	NCIH2009	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.3933092090604313	[1341]	[2816,2555,2078]	5	hSpCas9	negative selection	7879433
66528983	66529006	16	+	27260156	NCIH2009	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.2435415609745607	[759]	[1363,1053,1375]	3	hSpCas9	negative selection	7879434
66531386	66531409	16	+	27260156	NCIH2009	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.345581281517641	[321]	[837,385,545]	5	hSpCas9	negative selection	7879435
66529053	66529076	16	-	27260156	NCIH2009	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.15009659945757825	[670]	[1191,988,968]	2	hSpCas9	negative selection	7943686
66531428	66531451	16	+	27260156	NCIH2009	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.0908204505704937	[70]	[122,47,114]	-1	hSpCas9	negative selection	7943687
66528993	66529016	16	-	27260156	NCIH2009	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.3091266311818172	[502]	[543,463,689]	-4	hSpCas9	negative selection	7943688
66531440	66531463	16	-	27260156	NCIH1373	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.39569437421417386	[1341]	[2337,1677,2547,362]	4	hSpCas9	negative selection	8000684
66528983	66529006	16	+	27260156	NCIH1373	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.642583290823882	[759]	[1953,1161,1186,292]	6	hSpCas9	negative selection	8000685
66531386	66531409	16	+	27260156	NCIH1373	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.14888103350736298	[321]	[525,251,402,119]	1	hSpCas9	negative selection	8000686
66529053	66529076	16	-	27260156	NCIH1373	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.8641428483943435	[670]	[1857,995,1438,337]	8	hSpCas9	negative selection	8064937
66531428	66531451	16	+	27260156	NCIH1373	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.7473976290989452	[70]	[27,8,88,16]	-6	hSpCas9	negative selection	8064938
66528993	66529016	16	-	27260156	NCIH1373	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.034035804901171585	[502]	[518,613,433,164]	0	hSpCas9	negative selection	8064939
66531440	66531463	16	-	27260156	PATU8902	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	-0.03106298958279763	[1341]	[1654,2000,1855,1779]	0	hSpCas9	negative selection	8121935
66528983	66529006	16	+	27260156	PATU8902	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.012544604344675081	[759]	[1372,895,647,1414]	0	hSpCas9	negative selection	8121936
66531386	66531409	16	+	27260156	PATU8902	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.314399018393661	[321]	[500,241,475,1091]	3	hSpCas9	negative selection	8121937
66529053	66529076	16	-	27260156	PATU8902	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.27873373971851545	[670]	[1359,847,787,1680]	3	hSpCas9	negative selection	8186188
66531428	66531451	16	+	27260156	PATU8902	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.20924040981733416	[70]	[63,7,170,74]	-2	hSpCas9	negative selection	8186189
66528993	66529016	16	-	27260156	PATU8902	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.38086706146893234	[502]	[548,533,386,740]	-4	hSpCas9	negative selection	8186190
66531440	66531463	16	-	27260156	PANC1	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.15483978217366312	[1341]	[1108,1571,1302,1203]	2	hSpCas9	negative selection	8243186
66528983	66529006	16	+	27260156	PANC1	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.12196814512828957	[759]	[870,783,565,631]	2	hSpCas9	negative selection	8243187
66531386	66531409	16	+	27260156	PANC1	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.3080501375307717	[321]	[435,275,367,278]	5	hSpCas9	negative selection	8243188
66529053	66529076	16	-	27260156	PANC1	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.5012790084620328	[670]	[763,1069,774,710]	7	hSpCas9	negative selection	8307439
66531428	66531451	16	+	27260156	PANC1	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.1902203053725522	[70]	[12,120,9,78]	-3	hSpCas9	negative selection	8307440
66528993	66529016	16	-	27260156	PANC1	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	0.14288088669417404	[502]	[375,485,586,458]	2	hSpCas9	negative selection	8307441
66531440	66531463	16	-	27260156	PANC0813	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.37377280068693985	[1341]	[2136,1782,2478,1792]	6	hSpCas9	negative selection	8364437
66528983	66529006	16	+	27260156	PANC0813	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.017534905323685956	[759]	[956,790,1050,742]	0	hSpCas9	negative selection	8364438
66531386	66531409	16	+	27260156	PANC0813	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.0823052391545796	[321]	[584,406,253,372]	1	hSpCas9	negative selection	8364439
66529053	66529076	16	-	27260156	PANC0813	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.2959600141972615	[670]	[1143,910,864,964]	5	hSpCas9	negative selection	8428690
66531428	66531451	16	+	27260156	PANC0813	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.4912302140037612	[70]	[73,25,32,102]	-6	hSpCas9	negative selection	8428691
66528993	66529016	16	-	27260156	PANC0813	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.028549632761736096	[502]	[620,675,455,566]	0	hSpCas9	negative selection	8428692
66531440	66531463	16	-	27260156	RDES	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.030517844813739314	[1341]	[1346,1473,1614,1935]	0	hSpCas9	negative selection	8485688
66528983	66529006	16	+	27260156	RDES	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.009728857654041967	[759]	[728,883,981,942]	0	hSpCas9	negative selection	8485689
66531386	66531409	16	+	27260156	RDES	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.21611662262739756	[321]	[328,417,512,481]	3	hSpCas9	negative selection	8485690
66529053	66529076	16	-	27260156	RDES	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.575166234272234	[670]	[1040,1053,1137,1398]	8	hSpCas9	negative selection	8549941
66531428	66531451	16	+	27260156	RDES	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.4619393808200618	[70]	[70,46,58,55]	-7	hSpCas9	negative selection	8549942
66528993	66529016	16	-	27260156	RDES	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.06971630049981593	[502]	[437,472,521,828]	-1	hSpCas9	negative selection	8549943
66531440	66531463	16	-	27260156	PC3	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	-0.017109886294460308	[1341]	[929,1347,2010,1291]	0	hSpCas9	negative selection	8606939
66528983	66529006	16	+	27260156	PC3	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.023742246219181307	[759]	[481,834,1232,756]	0	hSpCas9	negative selection	8606940
66531386	66531409	16	+	27260156	PC3	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.10866283807674715	[321]	[204,261,349,409]	-2	hSpCas9	negative selection	8606941
66529053	66529076	16	-	27260156	PC3	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.30713016203575794	[670]	[469,741,1364,1039]	6	hSpCas9	negative selection	8671192
66531428	66531451	16	+	27260156	PC3	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.5231243615156154	[70]	[18,52,47,87]	-8	hSpCas9	negative selection	8671193
66528993	66529016	16	-	27260156	PC3	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.19907796406890357	[502]	[302,420,805,370]	-4	hSpCas9	negative selection	8671194
66531440	66531463	16	-	27260156	PATU8988T	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.026249013698391277	[1341]	[1468,1477,972,1386]	0	hSpCas9	negative selection	8728190
66528983	66529006	16	+	27260156	PATU8988T	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.06645466686610124	[759]	[782,772,560,978]	1	hSpCas9	negative selection	8728191
66531386	66531409	16	+	27260156	PATU8988T	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.16082304345911613	[321]	[434,316,232,409]	2	hSpCas9	negative selection	8728192
66529053	66529076	16	-	27260156	PATU8988T	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.6588608944853814	[670]	[922,1201,905,1086]	9	hSpCas9	negative selection	8792443
66531428	66531451	16	+	27260156	PATU8988T	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.10085659116084233	[70]	[75,64,42,72]	-2	hSpCas9	negative selection	8792444
66528993	66529016	16	-	27260156	PATU8988T	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.4779825097985583	[502]	[254,378,284,491]	-7	hSpCas9	negative selection	8792445
66531440	66531463	16	-	27260156	T47D	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.172936680496647	[1341]	[1841,1487,1902,1840]	3	hSpCas9	negative selection	8849441
66528983	66529006	16	+	27260156	T47D	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.05221073430069978	[759]	[873,778,1041,988]	1	hSpCas9	negative selection	8849442
66531386	66531409	16	+	27260156	T47D	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.2849469584975371	[321]	[500,409,487,431]	6	hSpCas9	negative selection	8849443
66529053	66529076	16	-	27260156	T47D	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.5339719794585948	[670]	[1180,1091,1079,1179]	9	hSpCas9	negative selection	8913694
66531428	66531451	16	+	27260156	T47D	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.7258425238640798	[70]	[60,43,38,56]	-8	hSpCas9	negative selection	8913695
66528993	66529016	16	-	27260156	T47D	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.06790261904890851	[502]	[487,541,601,605]	-1	hSpCas9	negative selection	8913696
66531440	66531463	16	-	27260156	SU8686	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.2823304614558588	[1341]	[1503,1541,1805,1639]	5	hSpCas9	negative selection	8970692
66528983	66529006	16	+	27260156	SU8686	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.12413318495556502	[759]	[774,668,826,1073]	2	hSpCas9	negative selection	8970693
66531386	66531409	16	+	27260156	SU8686	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.05683653768793656	[321]	[269,273,388,423]	0	hSpCas9	negative selection	8970694
66529053	66529076	16	-	27260156	SU8686	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.5783099012059633	[670]	[843,933,1038,1209]	8	hSpCas9	negative selection	9034945
66531428	66531451	16	+	27260156	SU8686	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-1.2684140397045347	[70]	[22,30,41,19]	-9	hSpCas9	negative selection	9034946
66528993	66529016	16	-	27260156	SU8686	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.08392628267831313	[502]	[530,330,436,612]	-1	hSpCas9	negative selection	9034947
66531440	66531463	16	-	27260156	SKES1	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	-0.026509724676378132	[1341]	[1404,1390,1331,1155]	0	hSpCas9	negative selection	9091943
66528983	66529006	16	+	27260156	SKES1	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.2232207474345163	[759]	[807,749,440,630]	-5	hSpCas9	negative selection	9091944
66531386	66531409	16	+	27260156	SKES1	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.19533176453794904	[321]	[497,332,270,378]	4	hSpCas9	negative selection	9091945
66529053	66529076	16	-	27260156	SKES1	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.3241207680973045	[670]	[880,1102,796,625]	6	hSpCas9	negative selection	9156196
66531428	66531451	16	+	27260156	SKES1	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.5165433058550941	[70]	[12,53,79,45]	-8	hSpCas9	negative selection	9156197
66528993	66529016	16	-	27260156	SKES1	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.4865167380569444	[502]	[291,445,381,314]	-8	hSpCas9	negative selection	9156198
66531440	66531463	16	-	27260156	TOV112D	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.08593812508118748	[1341]	[1439,2029,1044,1340]	1	hSpCas9	negative selection	9213194
66528983	66529006	16	+	27260156	TOV112D	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	0.06040338371867693	[759]	[652,1247,740,635]	1	hSpCas9	negative selection	9213195
66531386	66531409	16	+	27260156	TOV112D	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.04800145053940974	[321]	[397,360,246,261]	-1	hSpCas9	negative selection	9213196
66529053	66529076	16	-	27260156	TOV112D	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.4847982273332896	[670]	[713,1163,1043,875]	8	hSpCas9	negative selection	9277447
66531428	66531451	16	+	27260156	TOV112D	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.6653022177959058	[70]	[56,64,44,18]	-8	hSpCas9	negative selection	9277448
66528993	66529016	16	-	27260156	TOV112D	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.3699967870778029	[502]	[330,478,425,340]	-6	hSpCas9	negative selection	9277449
66531440	66531463	16	-	27260156	TC71	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.03496341130630776	[1341]	[1628,1461,1424,1370]	0	hSpCas9	negative selection	9334445
66528983	66529006	16	+	27260156	TC71	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.04977185847479526	[759]	[695,683,826,951]	-1	hSpCas9	negative selection	9334446
66531386	66531409	16	+	27260156	TC71	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.007693428004701519	[321]	[287,401,366,314]	0	hSpCas9	negative selection	9334447
66529053	66529076	16	-	27260156	TC71	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.4877906565673521	[670]	[1046,936,945,1111]	9	hSpCas9	negative selection	9398698
66531428	66531451	16	+	27260156	TC71	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-1.2629603468488813	[70]	[83,24,7,7]	-9	hSpCas9	negative selection	9398699
66528993	66529016	16	-	27260156	TC71	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.2196023570296881	[502]	[414,469,492,474]	-5	hSpCas9	negative selection	9398700
66531440	66531463	16	-	27260156	TC32	viability	TGTACCACGATGCCTCTCGCTGG	TK2	ENSG00000166548	0.1318103881492385	[1341]	[1208,1058,1906,1512]	2	hSpCas9	negative selection	9455696
66528983	66529006	16	+	27260156	TC32	viability	AACTACAGTACCTTCTATACAGG	TK2	ENSG00000166548	-0.056875456470606656	[759]	[597,584,777,815]	-1	hSpCas9	negative selection	9455697
66531386	66531409	16	+	27260156	TC32	viability	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.19371340294899525	[321]	[361,200,352,511]	3	hSpCas9	negative selection	9455698
66529053	66529076	16	-	27260156	TC32	viability	TCCTTTAGGTGTCATCTGTACGG	TK2	ENSG00000166548	0.473536182437278	[670]	[1019,580,1184,805]	7	hSpCas9	negative selection	9519949
66531428	66531451	16	+	27260156	TC32	viability	TAGCGTAAGACCCCAGCGAGAGG	TK2	ENSG00000166548	-0.870623173501587	[70]	[15,18,74,50]	-9	hSpCas9	negative selection	9519950
66528993	66529016	16	-	27260156	TC32	viability	TTGTAGAAAACCTGTATAGAAGG	TK2	ENSG00000166548	-0.0012103023136851854	[502]	[530,432,324,554]	0	hSpCas9	negative selection	9519951
66513798	66513821	16	+	27869803	HPAFII	viability after 27 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	0.25030320367086767	[98]	[104,25,NaN]	2	hSpCas9	negative selection	9557728
66517189	66517212	16	+	27869803	HPAFII	viability after 27 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.1436339774589599	[156]	[118,67,NaN]	1	hSpCas9	negative selection	9557729
66529041	66529064	16	-	27869803	HPAFII	viability after 27 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	1.6670030943374317	[191]	[169,445,NaN]	9	hSpCas9	negative selection	9557730
66531386	66531409	16	+	27869803	HPAFII	viability after 27 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.7132130833887851	[583]	[636,391,NaN]	6	hSpCas9	negative selection	9557731
66536991	66537014	16	-	27869803	HPAFII	viability after 27 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.48029426560049565	[206]	[87,204,NaN]	4	hSpCas9	negative selection	9557732
66513798	66513821	16	+	27869803	HPAFII	viability after 15 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	0.4438861141839312	[98]	[280,59,NaN]	5	hSpCas9	negative selection	9640177
66517189	66517212	16	+	27869803	HPAFII	viability after 15 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.09966216322408561	[156]	[191,135,NaN]	-1	hSpCas9	negative selection	9640178
66529041	66529064	16	-	27869803	HPAFII	viability after 15 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.7472523712855634	[191]	[428,294,NaN]	8	hSpCas9	negative selection	9640179
66531386	66531409	16	+	27869803	HPAFII	viability after 15 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.39031782657028824	[583]	[887,781,NaN]	4	hSpCas9	negative selection	9640180
66536991	66537014	16	-	27869803	HPAFII	viability after 15 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.445788451059684	[206]	[294,307,NaN]	5	hSpCas9	negative selection	9640181
66513798	66513821	16	+	27869803	ASPC1	viability after 36 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-0.14758020561239849	[181]	[38,71,57]	-1	hSpCas9	negative selection	9722626
66517189	66517212	16	+	27869803	ASPC1	viability after 36 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-1.1114519794892004	[280]	[87,52,8]	-8	hSpCas9	negative selection	9722627
66529041	66529064	16	-	27869803	ASPC1	viability after 36 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.44059933662341877	[471]	[297,229,163]	4	hSpCas9	negative selection	9722628
66531386	66531409	16	+	27869803	ASPC1	viability after 36 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.6549006183802151	[1306]	[1050,471,672]	6	hSpCas9	negative selection	9722629
66536991	66537014	16	-	27869803	ASPC1	viability after 36 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.445210750950201	[602]	[308,429,153]	4	hSpCas9	negative selection	9722630
66513798	66513821	16	+	27869803	PATU8988S	viability after 35 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-0.35833819872472383	[201]	[46,79,NaN]	-4	hSpCas9	negative selection	9805075
66517189	66517212	16	+	27869803	PATU8988S	viability after 35 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.1260827702184273	[262]	[122,70,NaN]	-1	hSpCas9	negative selection	9805076
66529041	66529064	16	-	27869803	PATU8988S	viability after 35 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	1.0534503328985765	[414]	[302,390,NaN]	9	hSpCas9	negative selection	9805077
66531386	66531409	16	+	27869803	PATU8988S	viability after 35 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	-0.05982855405458776	[1338]	[462,571,NaN]	0	hSpCas9	negative selection	9805078
66536991	66537014	16	-	27869803	PATU8988S	viability after 35 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.1947554492064208	[511]	[240,230,NaN]	2	hSpCas9	negative selection	9805079
66513798	66513821	16	+	27869803	PATU8988S	viability after 31 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-0.8234823814501389	[201]	[19,77,NaN]	-7	hSpCas9	negative selection	9887524
66517189	66517212	16	+	27869803	PATU8988S	viability after 31 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.7388113693121181	[262]	[68,54,NaN]	-7	hSpCas9	negative selection	9887525
66529041	66529064	16	-	27869803	PATU8988S	viability after 31 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.5096592914785355	[414]	[206,271,NaN]	6	hSpCas9	negative selection	9887526
66531386	66531409	16	+	27869803	PATU8988S	viability after 31 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.14241704450342652	[1338]	[554,632,NaN]	1	hSpCas9	negative selection	9887527
66536991	66537014	16	-	27869803	PATU8988S	viability after 31 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.0720557739528416	[511]	[273,138,NaN]	0	hSpCas9	negative selection	9887528
66513798	66513821	16	+	27869803	HPAFII	viability after 35 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	-0.14934524824392037	[98]	[71,14,NaN]	-1	hSpCas9	negative selection	9969973
66517189	66517212	16	+	27869803	HPAFII	viability after 35 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.7120903664998441	[156]	[24,74,NaN]	-4	hSpCas9	negative selection	9969974
66529041	66529064	16	-	27869803	HPAFII	viability after 35 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	2.092278677286009	[191]	[191,664,NaN]	9	hSpCas9	negative selection	9969975
66531386	66531409	16	+	27869803	HPAFII	viability after 35 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.8555098472629674	[583]	[422,660,NaN]	5	hSpCas9	negative selection	9969976
66536991	66537014	16	-	27869803	HPAFII	viability after 35 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.9259710546410045	[206]	[49,366,NaN]	6	hSpCas9	negative selection	9969977
66513798	66513821	16	+	27869803	HPAFII	viability after 31 days	GCTTCCAGGTATTCCTGCCAGGG	TK2	ENSG00000166548	0.2575914266935777	[98]	[86,43,NaN]	1	hSpCas9	negative selection	10052422
66517189	66517212	16	+	27869803	HPAFII	viability after 31 days	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-1.2515176979112552	[156]	[25,48,NaN]	-6	hSpCas9	negative selection	10052423
66529041	66529064	16	-	27869803	HPAFII	viability after 31 days	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	2.0324358676179175	[191]	[190,712,NaN]	9	hSpCas9	negative selection	10052424
66531386	66531409	16	+	27869803	HPAFII	viability after 31 days	ACGAGTATGCCTGTCCAGCATGG	TK2	ENSG00000166548	0.9527793578814165	[583]	[698,563,NaN]	7	hSpCas9	negative selection	10052425
66536991	66537014	16	-	27869803	HPAFII	viability after 31 days	TAACGGAGCCTGTGTCCAAGTGG	TK2	ENSG00000166548	0.5663886273147392	[206]	[60,292,NaN]	4	hSpCas9	negative selection	10052426
66513769	66513792	16	+	28162770	P31FUJ	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.3512114669132287	[506]	[759]	4	hSpCas9	negative selection	10251026
66517835	66517858	16	-	28162770	P31FUJ	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.22067864533188922	[236]	[238]	-2	hSpCas9	negative selection	10251027
66513745	66513768	16	-	28162770	P31FUJ	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	-0.2918376747113307	[423]	[406]	-3	hSpCas9	negative selection	10251028
66513719	66513742	16	+	28162770	P31FUJ	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	-0.18127190377429647	[54]	[56]	-2	hSpCas9	negative selection	10251029
66531436	66531459	16	+	28162770	P31FUJ	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.06604227735994228	[125]	[154]	0	hSpCas9	negative selection	10251030
66517160	66517183	16	-	28162770	P31FUJ	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.4004154649139987	[97]	[151]	4	hSpCas9	negative selection	10251031
66517135	66517158	16	-	28162770	P31FUJ	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	-0.03707773354001065	[116]	[133]	0	hSpCas9	negative selection	10251032
66513730	66513753	16	+	28162770	P31FUJ	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	0.4225496241981755	[159]	[251]	5	hSpCas9	negative selection	10251033
66517189	66517212	16	+	28162770	P31FUJ	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.8409990959957381	[361]	[761]	8	hSpCas9	negative selection	10251034
66529041	66529064	16	-	28162770	P31FUJ	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.17835442039200222	[103]	[107]	-2	hSpCas9	negative selection	10251035
66513769	66513792	16	+	28162770	TF1	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	NaN	[NaN]	[601]	1	hSpCas9	negative selection	10420392
66517835	66517858	16	-	28162770	TF1	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10420393
66513745	66513768	16	-	28162770	TF1	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	NaN	[NaN]	[326]	1	hSpCas9	negative selection	10420394
66513719	66513742	16	+	28162770	TF1	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10420395
66531436	66531459	16	+	28162770	TF1	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	NaN	[NaN]	[124]	1	hSpCas9	negative selection	10420396
66517160	66517183	16	-	28162770	TF1	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	NaN	[NaN]	[124]	1	hSpCas9	negative selection	10420397
66517135	66517158	16	-	28162770	TF1	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	NaN	[NaN]	[168]	1	hSpCas9	negative selection	10420398
66513730	66513753	16	+	28162770	TF1	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10420399
66517189	66517212	16	+	28162770	TF1	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	NaN	[NaN]	[452]	1	hSpCas9	negative selection	10420400
66529041	66529064	16	-	28162770	TF1	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	NaN	[NaN]	[168]	1	hSpCas9	negative selection	10420401
66513769	66513792	16	+	28162770	SKM1	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.19969337307731316	[164]	[334]	2	hSpCas9	negative selection	10589758
66517835	66517858	16	-	28162770	SKM1	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.04439411935845339	[34]	[59]	0	hSpCas9	negative selection	10589759
66513745	66513768	16	-	28162770	SKM1	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.37593767958990343	[101]	[233]	3	hSpCas9	negative selection	10589760
66513719	66513742	16	+	28162770	SKM1	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	0.4999263968653569	[15]	[39]	5	hSpCas9	negative selection	10589761
66531436	66531459	16	+	28162770	SKM1	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	-0.37948346232105457	[38]	[52]	-3	hSpCas9	negative selection	10589762
66517160	66517183	16	-	28162770	SKM1	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	-0.6991449502364719	[44]	[48]	-5	hSpCas9	negative selection	10589763
66517135	66517158	16	-	28162770	SKM1	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	0.12355051795561822	[26]	[51]	1	hSpCas9	negative selection	10589764
66513730	66513753	16	+	28162770	SKM1	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	0.056692005755860975	[30]	[56]	0	hSpCas9	negative selection	10589765
66517189	66517212	16	+	28162770	SKM1	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.7489539447052713	[68]	[204]	7	hSpCas9	negative selection	10589766
66529041	66529064	16	-	28162770	SKM1	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.5000736031346429	[23]	[29]	-4	hSpCas9	negative selection	10589767
66513769	66513792	16	+	28162770	SKM1	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.19969337307731316	[164]	[334]	2	hSpCas9	negative selection	10759124
66517835	66517858	16	-	28162770	SKM1	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.04439411935845339	[34]	[59]	0	hSpCas9	negative selection	10759125
66513745	66513768	16	-	28162770	SKM1	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.37593767958990343	[101]	[233]	3	hSpCas9	negative selection	10759126
66513719	66513742	16	+	28162770	SKM1	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	0.4999263968653569	[15]	[39]	5	hSpCas9	negative selection	10759127
66531436	66531459	16	+	28162770	SKM1	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	-0.37948346232105457	[38]	[52]	-3	hSpCas9	negative selection	10759128
66517160	66517183	16	-	28162770	SKM1	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	-0.6991449502364719	[44]	[48]	-5	hSpCas9	negative selection	10759129
66517135	66517158	16	-	28162770	SKM1	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	0.12355051795561822	[26]	[51]	1	hSpCas9	negative selection	10759130
66513730	66513753	16	+	28162770	SKM1	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	0.056692005755860975	[30]	[56]	0	hSpCas9	negative selection	10759131
66517189	66517212	16	+	28162770	SKM1	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.7489539447052713	[68]	[204]	7	hSpCas9	negative selection	10759132
66529041	66529064	16	-	28162770	SKM1	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.5000736031346429	[23]	[29]	-4	hSpCas9	negative selection	10759133
66513769	66513792	16	+	28162770	PL21	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	-0.24043297689666132	[607]	[223]	-2	hSpCas9	negative selection	10928490
66517835	66517858	16	-	28162770	PL21	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-1.3755450726438252	[154]	[25]	-7	hSpCas9	negative selection	10928491
66513745	66513768	16	-	28162770	PL21	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.46895637291712	[414]	[249]	4	hSpCas9	negative selection	10928492
66513719	66513742	16	+	28162770	PL21	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	1.805001672648181	[47]	[72]	9	hSpCas9	negative selection	10928493
66531436	66531459	16	+	28162770	PL21	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	1.1330254186307833	[131]	[125]	8	hSpCas9	negative selection	10928494
66517160	66517183	16	-	28162770	PL21	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.12213710248804696	[170]	[80]	1	hSpCas9	negative selection	10928495
66517135	66517158	16	-	28162770	PL21	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	0.23761431990798298	[75]	[38]	2	hSpCas9	negative selection	10928496
66513730	66513753	16	+	28162770	PL21	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	0.2868512476826511	[112]	[59]	2	hSpCas9	negative selection	10928497
66517189	66517212	16	+	28162770	PL21	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	1.1843146473276376	[274]	[271]	8	hSpCas9	negative selection	10928498
66529041	66529064	16	-	28162770	PL21	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.7987770521075527	[69]	[52]	6	hSpCas9	negative selection	10928499
66513769	66513792	16	+	28162770	P31FUJ	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.3512114669132287	[506]	[759]	4	hSpCas9	negative selection	11097856
66517835	66517858	16	-	28162770	P31FUJ	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.22067864533188922	[236]	[238]	-2	hSpCas9	negative selection	11097857
66513745	66513768	16	-	28162770	P31FUJ	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	-0.2918376747113307	[423]	[406]	-3	hSpCas9	negative selection	11097858
66513719	66513742	16	+	28162770	P31FUJ	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	-0.18127190377429647	[54]	[56]	-2	hSpCas9	negative selection	11097859
66531436	66531459	16	+	28162770	P31FUJ	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.06604227735994228	[125]	[154]	0	hSpCas9	negative selection	11097860
66517160	66517183	16	-	28162770	P31FUJ	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.4004154649139987	[97]	[151]	4	hSpCas9	negative selection	11097861
66517135	66517158	16	-	28162770	P31FUJ	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	-0.03707773354001065	[116]	[133]	0	hSpCas9	negative selection	11097862
66513730	66513753	16	+	28162770	P31FUJ	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	0.4225496241981755	[159]	[251]	5	hSpCas9	negative selection	11097863
66517189	66517212	16	+	28162770	P31FUJ	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.8409990959957381	[361]	[761]	8	hSpCas9	negative selection	11097864
66529041	66529064	16	-	28162770	P31FUJ	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.17835442039200222	[103]	[107]	-2	hSpCas9	negative selection	11097865
66513769	66513792	16	+	28162770	OCIAML5	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.5537802164348544	[373]	[990]	5	hSpCas9	negative selection	11267222
66517835	66517858	16	-	28162770	OCIAML5	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.2484883919754938	[153]	[233]	-2	hSpCas9	negative selection	11267223
66513745	66513768	16	-	28162770	OCIAML5	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.18770395782860383	[160]	[330]	1	hSpCas9	negative selection	11267224
66513719	66513742	16	+	28162770	OCIAML5	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	2.45536195432825	[19]	[197]	9	hSpCas9	negative selection	11267225
66531436	66531459	16	+	28162770	OCIAML5	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.9388378304130126	[62]	[217]	7	hSpCas9	negative selection	11267226
66517160	66517183	16	-	28162770	OCIAML5	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	-0.25482574036440414	[116]	[176]	-2	hSpCas9	negative selection	11267227
66517135	66517158	16	-	28162770	OCIAML5	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	-0.3602134745343223	[63]	[89]	-3	hSpCas9	negative selection	11267228
66513730	66513753	16	+	28162770	OCIAML5	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	0.5767767279398772	[64]	[174]	5	hSpCas9	negative selection	11267229
66517189	66517212	16	+	28162770	OCIAML5	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	1.3357934445130222	[150]	[687]	9	hSpCas9	negative selection	11267230
66529041	66529064	16	-	28162770	OCIAML5	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-1.4587241426844724	[66]	[43]	-7	hSpCas9	negative selection	11267231
66513769	66513792	16	+	28162770	EOL1	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	-0.21485528509488216	[1063]	[482]	-2	hSpCas9	negative selection	11436588
66517835	66517858	16	-	28162770	EOL1	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	0.14403446173157153	[212]	[123]	1	hSpCas9	negative selection	11436589
66513745	66513768	16	-	28162770	EOL1	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.38140544654400554	[611]	[419]	3	hSpCas9	negative selection	11436590
66513719	66513742	16	+	28162770	EOL1	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	-1.1149805926161027	[147]	[35]	-6	hSpCas9	negative selection	11436591
66531436	66531459	16	+	28162770	EOL1	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.017657175962015992	[209]	[111]	0	hSpCas9	negative selection	11436592
66517160	66517183	16	-	28162770	EOL1	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.5858963190920456	[281]	[222]	5	hSpCas9	negative selection	11436593
66517135	66517158	16	-	28162770	EOL1	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	1.0531319776319474	[117]	[128]	8	hSpCas9	negative selection	11436594
66513730	66513753	16	+	28162770	EOL1	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	-0.616020609792168	[191]	[65]	-4	hSpCas9	negative selection	11436595
66517189	66517212	16	+	28162770	EOL1	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.41209777063374653	[387]	[271]	4	hSpCas9	negative selection	11436596
66529041	66529064	16	-	28162770	EOL1	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.5709108169558341	[91]	[71]	5	hSpCas9	negative selection	11436597
66513769	66513792	16	+	28162770	MOLM13	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	1.186438741528954	[882]	[1452]	8	hSpCas9	negative selection	11605954
66517835	66517858	16	-	28162770	MOLM13	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	1.737455860875126	[201]	[486]	9	hSpCas9	negative selection	11605955
66513745	66513768	16	-	28162770	MOLM13	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.6922736505547232	[516]	[603]	5	hSpCas9	negative selection	11605956
66513719	66513742	16	+	28162770	MOLM13	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	0.15422890264081723	[86]	[69]	1	hSpCas9	negative selection	11605957
66531436	66531459	16	+	28162770	MOLM13	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.46788938154457893	[193]	[193]	3	hSpCas9	negative selection	11605958
66517160	66517183	16	-	28162770	MOLM13	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	-0.12698858804165997	[218]	[144]	-1	hSpCas9	negative selection	11605959
66517135	66517158	16	-	28162770	MOLM13	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	0.07932409362692594	[143]	[109]	0	hSpCas9	negative selection	11605960
66513730	66513753	16	+	28162770	MOLM13	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	-0.137138742230683	[180]	[118]	-1	hSpCas9	negative selection	11605961
66517189	66517212	16	+	28162770	MOLM13	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.752728157696721	[393]	[479]	6	hSpCas9	negative selection	11605962
66529041	66529064	16	-	28162770	MOLM13	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-2.9244280412341817	[104]	[9]	-8	hSpCas9	negative selection	11605963
66513769	66513792	16	+	28162770	HEL	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.7622996162661311	[786]	[854]	6	hSpCas9	negative selection	11775320
66517835	66517858	16	-	28162770	HEL	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.4653209138570959	[193]	[89]	-3	hSpCas9	negative selection	11775321
66513745	66513768	16	-	28162770	HEL	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.9938406869193733	[420]	[536]	8	hSpCas9	negative selection	11775322
66513719	66513742	16	+	28162770	HEL	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	1.3997620785078166	[99]	[168]	9	hSpCas9	negative selection	11775323
66531436	66531459	16	+	28162770	HEL	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	1.0212504552540866	[149]	[194]	8	hSpCas9	negative selection	11775324
66517160	66517183	16	-	28162770	HEL	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.8678766300756222	[224]	[262]	7	hSpCas9	negative selection	11775325
66517135	66517158	16	-	28162770	HEL	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	0.5331143408258587	[81]	[75]	4	hSpCas9	negative selection	11775326
66513730	66513753	16	+	28162770	HEL	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	1.7095703404785656	[115]	[242]	9	hSpCas9	negative selection	11775327
66517189	66517212	16	+	28162770	HEL	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.9485472615244424	[287]	[355]	8	hSpCas9	negative selection	11775328
66529041	66529064	16	-	28162770	HEL	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.05016314716932535	[94]	[62]	0	hSpCas9	negative selection	11775329
66513769	66513792	16	+	28162770	MV411	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.7415466210528181	[567]	[799]	6	hSpCas9	negative selection	11944686
66517835	66517858	16	-	28162770	MV411	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	0.5884744686178421	[89]	[113]	5	hSpCas9	negative selection	11944687
66513745	66513768	16	-	28162770	MV411	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.632260437014611	[385]	[503]	6	hSpCas9	negative selection	11944688
66513719	66513742	16	+	28162770	MV411	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	0.22606389999020826	[67]	[66]	2	hSpCas9	negative selection	11944689
66531436	66531459	16	+	28162770	MV411	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.5818565898533344	[160]	[202]	5	hSpCas9	negative selection	11944690
66517160	66517183	16	-	28162770	MV411	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.5483040301423079	[137]	[169]	5	hSpCas9	negative selection	11944691
66517135	66517158	16	-	28162770	MV411	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	0.8375617566197102	[92]	[139]	7	hSpCas9	negative selection	11944692
66513730	66513753	16	+	28162770	MV411	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	0.1173770102184023	[115]	[105]	1	hSpCas9	negative selection	11944693
66517189	66517212	16	+	28162770	MV411	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.12052543830055562	[284]	[260]	1	hSpCas9	negative selection	11944694
66529041	66529064	16	-	28162770	MV411	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.37434966326499497	[86]	[94]	3	hSpCas9	negative selection	11944695
66513769	66513792	16	+	28162770	MONOMAC1	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.790326327262521	[343]	[681]	7	hSpCas9	negative selection	12114052
66517835	66517858	16	-	28162770	MONOMAC1	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.6504024649974971	[88]	[64]	-5	hSpCas9	negative selection	12114053
66513745	66513768	16	-	28162770	MONOMAC1	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.7793334065555468	[276]	[544]	7	hSpCas9	negative selection	12114054
66513719	66513742	16	+	28162770	MONOMAC1	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	0.2554753576379529	[56]	[77]	2	hSpCas9	negative selection	12114055
66531436	66531459	16	+	28162770	MONOMAC1	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	-0.5036981852936055	[93]	[75]	-4	hSpCas9	negative selection	12114056
66517160	66517183	16	-	28162770	MONOMAC1	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.5507761293436448	[105]	[177]	5	hSpCas9	negative selection	12114057
66517135	66517158	16	-	28162770	MONOMAC1	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	0.6904884236820339	[59]	[110]	6	hSpCas9	negative selection	12114058
66513730	66513753	16	+	28162770	MONOMAC1	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	1.135159583281636	[55]	[140]	8	hSpCas9	negative selection	12114059
66517189	66517212	16	+	28162770	MONOMAC1	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.21117938636327604	[158]	[210]	2	hSpCas9	negative selection	12114060
66529041	66529064	16	-	28162770	MONOMAC1	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	1.4506614090095653	[44]	[140]	9	hSpCas9	negative selection	12114061
66513769	66513792	16	+	28162770	OCIAML2	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	0.5877868609831609	[120]	[1007]	6	hSpCas9	negative selection	12283418
66517835	66517858	16	-	28162770	OCIAML2	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.036001597605436475	[31]	[172]	0	hSpCas9	negative selection	12283419
66513745	66513768	16	-	28162770	OCIAML2	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	0.1602485105343533	[66]	[414]	1	hSpCas9	negative selection	12283420
66513719	66513742	16	+	28162770	OCIAML2	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	-0.6863585162975985	[17]	[61]	-5	hSpCas9	negative selection	12283421
66531436	66531459	16	+	28162770	OCIAML2	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	0.6527525902631209	[20]	[182]	6	hSpCas9	negative selection	12283422
66517160	66517183	16	-	28162770	OCIAML2	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.3054741628310033	[39]	[273]	3	hSpCas9	negative selection	12283423
66517135	66517158	16	-	28162770	OCIAML2	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	-0.13434643737772867	[19]	[100]	-1	hSpCas9	negative selection	12283424
66513730	66513753	16	+	28162770	OCIAML2	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	0.483566485144714	[15]	[123]	5	hSpCas9	negative selection	12283425
66517189	66517212	16	+	28162770	OCIAML2	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	-0.08980804130123027	[47]	[249]	0	hSpCas9	negative selection	12283426
66529041	66529064	16	-	28162770	OCIAML2	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	0.5128820519692698	[10]	[86]	5	hSpCas9	negative selection	12283427
66513769	66513792	16	+	28162770	OCIAML3	viability	TGAGCCACTCCTCATGGAGATGG	TK2	ENSG00000166548	-0.22054924479671878	[175]	[455]	-2	hSpCas9	negative selection	12452784
66517835	66517858	16	-	28162770	OCIAML3	viability	ACTATGTAGTTCTGTCGGAATGG	TK2	ENSG00000166548	-0.28415237773737584	[47]	[118]	-2	hSpCas9	negative selection	12452785
66513745	66513768	16	-	28162770	OCIAML3	viability	CAAAGGCAGCCTTTTCCCCATGG	TK2	ENSG00000166548	-0.5805871245618417	[106]	[215]	-4	hSpCas9	negative selection	12452786
66513719	66513742	16	+	28162770	OCIAML3	viability	AGTCTTACTTACCAGAACAGGGG	TK2	ENSG00000166548	0.7818592616740028	[20]	[108]	7	hSpCas9	negative selection	12452787
66531436	66531459	16	+	28162770	OCIAML3	viability	GACCCCAGCGAGAGGCATCGTGG	TK2	ENSG00000166548	-0.8764073710248881	[44]	[73]	-6	hSpCas9	negative selection	12452788
66517160	66517183	16	-	28162770	OCIAML3	viability	AGAGGTTAAAGAAGAGATGCAGG	TK2	ENSG00000166548	0.17354627367546593	[41]	[142]	1	hSpCas9	negative selection	12452789
66517135	66517158	16	-	28162770	OCIAML3	viability	AGAGGAGAAGGTCATTCCGCTGG	TK2	ENSG00000166548	-0.2349265470193349	[22]	[58]	-2	hSpCas9	negative selection	12452790
66513730	66513753	16	+	28162770	OCIAML3	viability	CCAGAACAGGGGCTGCCATGGGG	TK2	ENSG00000166548	0.7394160934010285	[24]	[125]	6	hSpCas9	negative selection	12452791
66517189	66517212	16	+	28162770	OCIAML3	viability	AAGTCTCAGGATTGGTCCGAAGG	TK2	ENSG00000166548	0.013253527505767249	[106]	[325]	0	hSpCas9	negative selection	12452792
66529041	66529064	16	-	28162770	OCIAML3	viability	CATCTGTACGGTTGATGGAGAGG	TK2	ENSG00000166548	-0.19346971074043462	[24]	[65]	-1	hSpCas9	negative selection	12452793