Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:9874
• Symbol:TLK1
• Description:tousled like kinase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/TLK1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
171006162	171006185	2	-	26472758	Jiyoye	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	0.7262438222539952	[100]	[125]	5	hSpCas9	negative selection	166074
171061135	171061158	2	-	26472758	Jiyoye	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.32471322131390057	[53]	[50]	2	hSpCas9	negative selection	166075
171053784	171053807	2	-	26472758	Jiyoye	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-1.5212713574690926	[235]	[61]	-7	hSpCas9	negative selection	166076
170996652	170996675	2	-	26472758	Jiyoye	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	-1.9851420412728866	[62]	[11]	-8	hSpCas9	negative selection	166077
171056556	171056579	2	-	26472758	Jiyoye	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.2894803388361187	[216]	[199]	2	hSpCas9	negative selection	166078
171053761	171053784	2	-	26472758	Jiyoye	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	5.494638222756212	[0]	[33]	9	hSpCas9	negative selection	166079
171056460	171056483	2	+	26472758	Jiyoye	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	-0.7658893274670062	[229]	[101]	-5	hSpCas9	negative selection	166080
171049892	171049915	2	-	26472758	Jiyoye	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	-0.8104160535667534	[99]	[42]	-5	hSpCas9	negative selection	166081
171049875	171049898	2	+	26472758	Jiyoye	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	1.1370862181381294	[122]	[203]	7	hSpCas9	negative selection	166082
171049846	171049869	2	-	26472758	Jiyoye	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	-0.4280137487484563	[313]	[175]	-3	hSpCas9	negative selection	166083
171006162	171006185	2	-	26472758	KBM7	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	-0.3871063365576213	[733,499]	[225,211]	-4	hSpCas9	negative selection	357192
171061135	171061158	2	-	26472758	KBM7	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.05310772377611983	[244,306]	[120,150]	0	hSpCas9	negative selection	357193
171053784	171053807	2	-	26472758	KBM7	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	0.3089602667009432	[615,323]	[324,213]	3	hSpCas9	negative selection	357194
170996652	170996675	2	-	26472758	KBM7	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	0.20927694878916636	[221,153]	[113,88]	2	hSpCas9	negative selection	357195
171056556	171056579	2	-	26472758	KBM7	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.46330215295318145	[986,674]	[625,445]	5	hSpCas9	negative selection	357196
171053761	171053784	2	-	26472758	KBM7	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	-0.7805345507503096	[208,119]	[43,43]	-6	hSpCas9	negative selection	357197
171056460	171056483	2	+	26472758	KBM7	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	0.3826555318973728	[529,577]	[318,363]	4	hSpCas9	negative selection	357198
171049892	171049915	2	-	26472758	KBM7	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	0.44762991404336766	[453,284]	[174,283]	5	hSpCas9	negative selection	357199
171049875	171049898	2	+	26472758	KBM7	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	0.4093750280186044	[707,562]	[381,404]	4	hSpCas9	negative selection	357200
171049846	171049869	2	-	26472758	KBM7	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.18276649507388665	[593,777]	[383,362]	1	hSpCas9	negative selection	357201
171006162	171006185	2	-	26472758	Raji	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	0.25752388480145993	[309]	[85]	2	hSpCas9	negative selection	548310
171061135	171061158	2	-	26472758	Raji	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.44225068596846007	[110]	[34]	4	hSpCas9	negative selection	548311
171053784	171053807	2	-	26472758	Raji	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	0.3995642868669097	[195]	[59]	4	hSpCas9	negative selection	548312
170996652	170996675	2	-	26472758	Raji	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	-1.0890136774299037	[54]	[5]	-7	hSpCas9	negative selection	548313
171056556	171056579	2	-	26472758	Raji	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.4522120323710406	[399]	[126]	4	hSpCas9	negative selection	548314
171053761	171053784	2	-	26472758	Raji	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	-0.5115262972708945	[85]	[13]	-4	hSpCas9	negative selection	548315
171056460	171056483	2	+	26472758	Raji	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	1.2170080265480976	[227]	[122]	9	hSpCas9	negative selection	548316
171049892	171049915	2	-	26472758	Raji	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	0.4966579385873615	[112]	[36]	5	hSpCas9	negative selection	548317
171049875	171049898	2	+	26472758	Raji	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	-0.2718303001309804	[410]	[78]	-2	hSpCas9	negative selection	548318
171049846	171049869	2	-	26472758	Raji	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.0466295042945033	[387]	[92]	0	hSpCas9	negative selection	548319
171006162	171006185	2	-	26472758	K562	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	-1.4533971127446057	[411]	[126]	-6	hSpCas9	negative selection	739428
171061135	171061158	2	-	26472758	K562	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.0592038551995393	[248]	[218]	0	hSpCas9	negative selection	739429
171053784	171053807	2	-	26472758	K562	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-1.3007427649967345	[428]	[146]	-6	hSpCas9	negative selection	739430
170996652	170996675	2	-	26472758	K562	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	0.7298455548366887	[94]	[132]	6	hSpCas9	negative selection	739431
171056556	171056579	2	-	26472758	K562	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.18674301676955007	[739]	[710]	1	hSpCas9	negative selection	739432
171053761	171053784	2	-	26472758	K562	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	0.765655630777216	[107]	[154]	6	hSpCas9	negative selection	739433
171056460	171056483	2	+	26472758	K562	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	0.9764855224198139	[530]	[881]	7	hSpCas9	negative selection	739434
171049892	171049915	2	-	26472758	K562	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	-0.08208209701073954	[236]	[188]	0	hSpCas9	negative selection	739435
171049875	171049898	2	+	26472758	K562	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	-0.32447307984102847	[490]	[330]	-2	hSpCas9	negative selection	739436
171049846	171049869	2	-	26472758	K562	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	-0.14114765312123334	[532]	[407]	-1	hSpCas9	negative selection	739437
171006160	171006183	2	-	26627737	DLD1	viability	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-0.2777675385555156	[116]	[44,38,9]	-3	hSpCas9	negative selection	809234
171056550	171056573	2	-	26627737	DLD1	viability	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	-0.10006085491497269	[634]	[230,186,143]	-1	hSpCas9	negative selection	809235
171160308	171160331	2	+	26627737	DLD1	viability	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	-0.017913415195016075	[418]	[275,84,38]	0	hSpCas9	negative selection	809236
171160315	171160338	2	+	26627737	DLD1	viability	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.3586839109532954	[818]	[195,254,156]	-4	hSpCas9	negative selection	809237
171006160	171006183	2	-	26627737	GBM cells	viability after 5 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	0.8664923971933081	[44]	[41,45]	9	hSpCas9	negative selection	891549
171056550	171056573	2	-	26627737	GBM cells	viability after 5 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.17387849080246132	[561]	[360,318]	2	hSpCas9	negative selection	891550
171160308	171160331	2	+	26627737	GBM cells	viability after 5 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.12130629622213374	[137]	[77,82]	2	hSpCas9	negative selection	891551
171160315	171160338	2	+	26627737	GBM cells	viability after 5 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.34637268279793987	[306]	[128,129]	-5	hSpCas9	negative selection	891552
171006160	171006183	2	-	26627737	GBM cells	viability after 13 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	0.6133999676579613	[44]	[54,22]	7	hSpCas9	negative selection	973864
171056550	171056573	2	-	26627737	GBM cells	viability after 13 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.15506954659838024	[561]	[365,317]	2	hSpCas9	negative selection	973865
171160308	171160331	2	+	26627737	GBM cells	viability after 13 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	-0.19754021321259263	[137]	[104,32]	-2	hSpCas9	negative selection	973866
171160315	171160338	2	+	26627737	GBM cells	viability after 13 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.39918010732156206	[306]	[122,128]	-5	hSpCas9	negative selection	973867
171006160	171006183	2	-	26627737	GBM cells	viability after 21 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	0.8131530291675448	[44]	[43,41]	7	hSpCas9	negative selection	1056179
171056550	171056573	2	-	26627737	GBM cells	viability after 21 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.5187996191734101	[561]	[461,414]	5	hSpCas9	negative selection	1056180
171160308	171160331	2	+	26627737	GBM cells	viability after 21 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	-1.116981573957803	[137]	[32,35]	-7	hSpCas9	negative selection	1056181
171160315	171160338	2	+	26627737	GBM cells	viability after 21 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	0.24490204726731263	[306]	[205,189]	2	hSpCas9	negative selection	1056182
171006160	171006183	2	-	26627737	RPE1	viability after 9 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	1.3919480219213103	[71]	[73,39]	7	hSpCas9	negative selection	1138494
171056550	171056573	2	-	26627737	RPE1	viability after 9 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.12606870703340955	[1237]	[315,560]	0	hSpCas9	negative selection	1138495
171160308	171160331	2	+	26627737	RPE1	viability after 9 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	-0.5338034547316567	[511]	[125,90]	-4	hSpCas9	negative selection	1138496
171160315	171160338	2	+	26627737	RPE1	viability after 9 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	0.9624940433355227	[926]	[179,1062]	6	hSpCas9	negative selection	1138497
171006160	171006183	2	-	26627737	RPE1	viability after 12 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	0.9322937479797839	[71]	[33,39]	6	hSpCas9	negative selection	1220809
171056550	171056573	2	-	26627737	RPE1	viability after 12 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.09885951867312948	[1237]	[413,294]	0	hSpCas9	negative selection	1220810
171160308	171160331	2	+	26627737	RPE1	viability after 12 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.09410033153332653	[511]	[208,80]	0	hSpCas9	negative selection	1220811
171160315	171160338	2	+	26627737	RPE1	viability after 12 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	1.3510125328510625	[926]	[118,1181]	7	hSpCas9	negative selection	1220812
171006160	171006183	2	-	26627737	RPE1	viability after 15 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	0.9882042080047517	[71]	[73,7]	6	hSpCas9	negative selection	1303124
171056550	171056573	2	-	26627737	RPE1	viability after 15 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.2902512780661034	[1237]	[554,305]	2	hSpCas9	negative selection	1303125
171160308	171160331	2	+	26627737	RPE1	viability after 15 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	-0.015620569965703046	[511]	[155,130]	0	hSpCas9	negative selection	1303126
171160315	171160338	2	+	26627737	RPE1	viability after 15 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	1.915371160464317	[926]	[164,1783]	8	hSpCas9	negative selection	1303127
171006160	171006183	2	-	26627737	RPE1	viability after 18 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	0.6637578802864885	[71]	[38,21]	4	hSpCas9	negative selection	1385439
171056550	171056573	2	-	26627737	RPE1	viability after 18 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	-0.025554252489812468	[1237]	[334,320]	0	hSpCas9	negative selection	1385440
171160308	171160331	2	+	26627737	RPE1	viability after 18 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.8844774527810779	[511]	[373,127]	5	hSpCas9	negative selection	1385441
171160315	171160338	2	+	26627737	RPE1	viability after 18 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	2.560877230420374	[926]	[81,2965]	9	hSpCas9	negative selection	1385442
171006160	171006183	2	-	26627737	HeLa	viability after 8 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-1.8823044683922208	[154]	[33,0,22]	-9	hSpCas9	negative selection	1467754
171056550	171056573	2	-	26627737	HeLa	viability after 8 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	-0.17654467151068076	[663]	[275,351,150]	-2	hSpCas9	negative selection	1467755
171160308	171160331	2	+	26627737	HeLa	viability after 8 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.16901566163400983	[272]	[165,199,47]	1	hSpCas9	negative selection	1467756
171160315	171160338	2	+	26627737	HeLa	viability after 8 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.09150072789617883	[342]	[172,47,201]	-1	hSpCas9	negative selection	1467757
171006160	171006183	2	-	26627737	HeLa	viability after 12 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-0.9693339276939408	[154]	[83,0,17]	-7	hSpCas9	negative selection	1550069
171056550	171056573	2	-	26627737	HeLa	viability after 12 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	-0.2811111297771767	[663]	[142,301,221]	-2	hSpCas9	negative selection	1550070
171160308	171160331	2	+	26627737	HeLa	viability after 12 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.41686872121858487	[272]	[108,118,225]	3	hSpCas9	negative selection	1550071
171160315	171160338	2	+	26627737	HeLa	viability after 12 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	0.903786786025391	[342]	[144,341,296]	7	hSpCas9	negative selection	1550072
171006160	171006183	2	-	26627737	HeLa	viability after 15 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-1.905162220152232	[154]	[35,0,12]	-9	hSpCas9	negative selection	1632384
171056550	171056573	2	-	26627737	HeLa	viability after 15 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.08955454778598981	[663]	[201,337,326]	0	hSpCas9	negative selection	1632385
171160308	171160331	2	+	26627737	HeLa	viability after 15 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.6212762506277405	[272]	[238,101,170]	5	hSpCas9	negative selection	1632386
171160315	171160338	2	+	26627737	HeLa	viability after 15 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	0.32696276242943634	[342]	[59,254,214]	2	hSpCas9	negative selection	1632387
171006160	171006183	2	-	26627737	HeLa	viability after 18 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-1.862533488049147	[154]	[24,0,12]	-9	hSpCas9	negative selection	1714699
171056550	171056573	2	-	26627737	HeLa	viability after 18 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.13815001511108094	[663]	[152,281,326]	1	hSpCas9	negative selection	1714700
171160308	171160331	2	+	26627737	HeLa	viability after 18 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.6575701616898069	[272]	[165,87,170]	5	hSpCas9	negative selection	1714701
171160315	171160338	2	+	26627737	HeLa	viability after 18 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	0.3472495434958275	[342]	[37,219,214]	3	hSpCas9	negative selection	1714702
171006160	171006183	2	-	26627737	HCT116	viability after 6 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	1.7332130143364153	[148]	[15,111]	8	hSpCas9	negative selection	1797014
171056550	171056573	2	-	26627737	HCT116	viability after 6 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.5602927153355681	[1062]	[277,228]	3	hSpCas9	negative selection	1797015
171160308	171160331	2	+	26627737	HCT116	viability after 6 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.8652043804497911	[530]	[46,209]	5	hSpCas9	negative selection	1797016
171160315	171160338	2	+	26627737	HCT116	viability after 6 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	0.3774555028172589	[1061]	[261,191]	2	hSpCas9	negative selection	1797017
171006160	171006183	2	-	26627737	HCT116	viability after 8 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-1.7615729792664194	[147]	[15,30,24]	-9	hSpCas9	negative selection	1879329
171056550	171056573	2	-	26627737	HCT116	viability after 8 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.4947552538319277	[411]	[309,287,360]	5	hSpCas9	negative selection	1879330
171160308	171160331	2	+	26627737	HCT116	viability after 8 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.6983268872543333	[89]	[104,68,67]	6	hSpCas9	negative selection	1879331
171160315	171160338	2	+	26627737	HCT116	viability after 8 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.14202575385105326	[443]	[125,278,257]	-1	hSpCas9	negative selection	1879332
171006160	171006183	2	-	26627737	HCT116	viability after 9 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-1.0337841142983453	[148]	[0,33]	-6	hSpCas9	negative selection	1961644
171056550	171056573	2	-	26627737	HCT116	viability after 9 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.749318046579238	[1062]	[451,496]	5	hSpCas9	negative selection	1961645
171160308	171160331	2	+	26627737	HCT116	viability after 9 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	-1.2251746444708422	[530]	[125,8]	-7	hSpCas9	negative selection	1961646
171160315	171160338	2	+	26627737	HCT116	viability after 9 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.6202773586747591	[1061]	[322,74]	-4	hSpCas9	negative selection	1961647
171006160	171006183	2	-	26627737	HCT116	viability after 12 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-1.1765442370211476	[147]	[17,47,38]	-8	hSpCas9	negative selection	2043959
171056550	171056573	2	-	26627737	HCT116	viability after 12 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.43620948038102897	[411]	[256,332,292]	4	hSpCas9	negative selection	2043960
171160308	171160331	2	+	26627737	HCT116	viability after 12 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.8917823315665484	[89]	[83,103,75]	7	hSpCas9	negative selection	2043961
171160315	171160338	2	+	26627737	HCT116	viability after 12 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.3101120300204557	[443]	[165,288,113]	-3	hSpCas9	negative selection	2043962
171006160	171006183	2	-	26627737	HCT116	viability after 15 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-1.0458071100193809	[147]	[50,56,16]	-8	hSpCas9	negative selection	2126274
171056550	171056573	2	-	26627737	HCT116	viability after 15 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.4701764345210166	[411]	[492,230,279]	4	hSpCas9	negative selection	2126275
171160308	171160331	2	+	26627737	HCT116	viability after 15 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.9366628062943737	[89]	[103,142,50]	7	hSpCas9	negative selection	2126276
171160315	171160338	2	+	26627737	HCT116	viability after 15 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.15942133007244164	[443]	[121,321,227]	-2	hSpCas9	negative selection	2126277
171006160	171006183	2	-	26627737	HCT116	viability after 18 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-1.791718644843676	[147]	[15,13,32]	-8	hSpCas9	negative selection	2208589
171056550	171056573	2	-	26627737	HCT116	viability after 18 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.7345769281008538	[411]	[358,407,216]	6	hSpCas9	negative selection	2208590
171160308	171160331	2	+	26627737	HCT116	viability after 18 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.6371967500079478	[89]	[67,41,95]	5	hSpCas9	negative selection	2208591
171160315	171160338	2	+	26627737	HCT116	viability after 18 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	0.3684161802500422	[443]	[214,270,348]	3	hSpCas9	negative selection	2208592
171049875	171049898	2	+	24336569	HL60	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	-0.3514864080766029	[951]	[1578]	-3	hSpCas9	negative selection	2300652
171049891	171049914	2	-	24336569	HL60	viability	TGCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	1.0869137746159376	[621]	[2795]	8	hSpCas9	negative selection	2300653
171050154	171050177	2	-	24336569	HL60	viability	AGGCTAACTGTGATCTCAGACGG	TLK1	ENSG00000198586	1.0180715729220182	[321]	[1379]	7	hSpCas9	negative selection	2300654
171053760	171053783	2	-	24336569	HL60	viability	ACGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	0.6004748813869673	[325]	[1045]	5	hSpCas9	negative selection	2300655
171055102	171055125	2	+	24336569	HL60	viability	AATTGCTTTGGTTGTACAATAGG	TLK1	ENSG00000198586	1.0058383074780042	[528]	[2247]	7	hSpCas9	negative selection	2300656
171056456	171056479	2	+	24336569	HL60	viability	TGAAAGATGACTTACAGATGAGG	TLK1	ENSG00000198586	-0.38206842670721186	[1275]	[2071]	-3	hSpCas9	negative selection	2300657
171056465	171056488	2	+	24336569	HL60	viability	ACTTACAGATGAGGAAGGAGTGG	TLK1	ENSG00000198586	0.32522331476225985	[1017]	[2698]	3	hSpCas9	negative selection	2300658
171056550	171056573	2	-	24336569	HL60	viability	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	1.136756457854197	[469]	[2186]	8	hSpCas9	negative selection	2300659
171061078	171061101	2	+	24336569	HL60	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	-1.845835852135754	[247]	[145]	-9	hSpCas9	negative selection	2300660
171061135	171061158	2	-	24336569	HL60	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.723219438015916	[694]	[2427]	6	hSpCas9	negative selection	2300661
171049875	171049898	2	+	24336569	KBM7	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	0.43515475128136855	[537]	[1983]	4	hSpCas9	negative selection	2367829
171049891	171049914	2	-	24336569	KBM7	viability	TGCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	0.6017641387813045	[775]	[3211]	5	hSpCas9	negative selection	2367830
171050154	171050177	2	-	24336569	KBM7	viability	AGGCTAACTGTGATCTCAGACGG	TLK1	ENSG00000198586	0.7512905019341416	[317]	[1459]	6	hSpCas9	negative selection	2367831
171053760	171053783	2	-	24336569	KBM7	viability	ACGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	0.7217120710633895	[252]	[1137]	6	hSpCas9	negative selection	2367832
171055102	171055125	2	+	24336569	KBM7	viability	AATTGCTTTGGTTGTACAATAGG	TLK1	ENSG00000198586	0.3333418078220576	[597]	[2054]	3	hSpCas9	negative selection	2367833
171056456	171056479	2	+	24336569	KBM7	viability	TGAAAGATGACTTACAGATGAGG	TLK1	ENSG00000198586	0.5864166187324115	[691]	[2833]	5	hSpCas9	negative selection	2367834
171056465	171056488	2	+	24336569	KBM7	viability	ACTTACAGATGAGGAAGGAGTGG	TLK1	ENSG00000198586	0.37307066295725044	[1002]	[3542]	3	hSpCas9	negative selection	2367835
171056550	171056573	2	-	24336569	KBM7	viability	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.03667992918902463	[617]	[1728]	0	hSpCas9	negative selection	2367836
171061078	171061101	2	+	24336569	KBM7	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	-0.5720265674733711	[120]	[221]	-4	hSpCas9	negative selection	2367837
171061135	171061158	2	-	24336569	KBM7	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.2396431473506938	[775]	[2498]	2	hSpCas9	negative selection	2367838
171047972	171047995	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGACTCTCACTCTGTCGCCCAGG	TLK1	ENSG00000198586	-0.49349443152993966	[60,430]	[31,45]	-2	dCas9-VP64	positive selection	2390910
171067067	171067090	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCTAGGGATTCGTGTTCAAAGG	TLK1	ENSG00000198586	-0.2102742240799977	[55,89]	[15,10]	-1	dCas9-VP64	positive selection	2400031
171067138	171067161	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATCACAGAATATGTGCACTTAGG	TLK1	ENSG00000198586	10.550945642449179	[814,232]	[108,357272]	9	dCas9-VP64	positive selection	2400032
171067082	171067105	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAAATAATTGTACAGACCTAGGG	TLK1	ENSG00000198586	-1.9696967927810576	[296,14]	[9,6]	-9	dCas9-VP64	positive selection	2400033
171197751	171197774	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGTCTCACTCTGTCACCCCAG	TLK1	ENSG00000198586	-1.860820956764289	[284,38]	[12,4]	-8	dCas9-VP64	positive selection	2407127
171223066	171223089	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATTTCAGCACTTTGGGAGGCAG	TLK1	ENSG00000198586	0.4920406076216166	[38,113]	[3,44]	2	dCas9-VP64	positive selection	2409959
171188661	171188684	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCATTGCACTCCAGCCCAG	TLK1	ENSG00000198586	-1.8772669929253083	[207,39]	[9,2]	-9	dCas9-VP64	positive selection	2411618
171177203	171177226	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCTGCAGTGAGCTGTGATCGG	TLK1	ENSG00000198586	-0.2191175493670201	[259,121]	[39,30]	-1	dCas9-VP64	positive selection	2412032
171160630	171160653	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGGAGGGAAAGGGGGAGAAG	TLK1	ENSG00000198586	1.7872327221598079	[0,4]	[0,3]	6	dCas9-VP64	positive selection	2416777
171161071	171161094	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGGAAGAGACTAGAGCGCCGG	TLK1	ENSG00000198586	0.6640544345123988	[16,56]	[19,3]	3	dCas9-VP64	positive selection	2441985
171160993	171161016	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGGCCGCGGGAGCAGGCTTGG	TLK1	ENSG00000198586	2.7561731395572138	[14,24]	[28,29]	8	dCas9-VP64	positive selection	2441986
171161016	171161039	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGGGACCTGCCAGGGGCTGG	TLK1	ENSG00000198586	1.737004879943286	[3,1]	[2,0]	6	dCas9-VP64	positive selection	2441987
171196392	171196415	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCACACCAGG	TLK1	ENSG00000198586	0.08350517940301261	[638,11]	[141,1]	0	dCas9-VP64	positive selection	2447551
171200912	171200935	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCCAGCCTGGGCTACAGAGAG	TLK1	ENSG00000198586	-0.9551243910692007	[6,111]	[7,3]	-5	dCas9-VP64	positive selection	2459152
171195376	171195399	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAGTCCCAGCTACTCCGG	TLK1	ENSG00000198586	0.4848717924049799	[259,492]	[140,88]	2	dCas9-VP64	positive selection	2468726
171021512	171021535	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCACTTTGGGAGGCAGAGGCCAG	TLK1	ENSG00000198586	1.3055372672802243	[104,28]	[48,21]	5	dCas9-VP64	positive selection	2470042
171047972	171047995	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGACTCTCACTCTGTCGCCCAGG	TLK1	ENSG00000198586	-0.2653854437935726	[87,215]	[32,47]	-3	dCas9-VP64	positive selection	2486165
171067067	171067090	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCTAGGGATTCGTGTTCAAAGG	TLK1	ENSG00000198586	0.34440575628175263	[155,351]	[106,101]	2	dCas9-VP64	positive selection	2495286
171067138	171067161	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATCACAGAATATGTGCACTTAGG	TLK1	ENSG00000198586	3.332320906119403	[288,198]	[115,1451]	9	dCas9-VP64	positive selection	2495287
171067082	171067105	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAAATAATTGTACAGACCTAGGG	TLK1	ENSG00000198586	0.46500402049725126	[154,156]	[80,59]	3	dCas9-VP64	positive selection	2495288
171197751	171197774	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGTCTCACTCTGTCACCCCAG	TLK1	ENSG00000198586	3.0218550163158255	[213,311]	[60,1292]	9	dCas9-VP64	positive selection	2502382
171223066	171223089	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATTTCAGCACTTTGGGAGGCAG	TLK1	ENSG00000198586	1.405058588213125	[134,129]	[221,14]	7	dCas9-VP64	positive selection	2505214
171188661	171188684	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCATTGCACTCCAGCCCAG	TLK1	ENSG00000198586	1.3157553862059514	[45,21]	[16,37]	7	dCas9-VP64	positive selection	2506873
171177203	171177226	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCTGCAGTGAGCTGTGATCGG	TLK1	ENSG00000198586	-0.13774130468097318	[186,55]	[21,49]	-1	dCas9-VP64	positive selection	2507287
171160630	171160653	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGGAGGGAAAGGGGGAGAAG	TLK1	ENSG00000198586	-1.0546577081059165	[65,8]	[6,3]	-8	dCas9-VP64	positive selection	2512032
171161071	171161094	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGGAAGAGACTAGAGCGCCGG	TLK1	ENSG00000198586	1.369952309874421	[69,18]	[51,23]	7	dCas9-VP64	positive selection	2537240
171160993	171161016	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGGCCGCGGGAGCAGGCTTGG	TLK1	ENSG00000198586	1.058805510286673	[86,36]	[78,7]	6	dCas9-VP64	positive selection	2537241
171161016	171161039	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGGGACCTGCCAGGGGCTGG	TLK1	ENSG00000198586	0.17582455948030107	[38,101]	[7,41]	1	dCas9-VP64	positive selection	2537242
171196392	171196415	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCACACCAGG	TLK1	ENSG00000198586	-0.14914508695783546	[201,22]	[49,17]	-1	dCas9-VP64	positive selection	2542806
171200912	171200935	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCCAGCCTGGGCTACAGAGAG	TLK1	ENSG00000198586	-0.22071864971822522	[77,140]	[18,40]	-2	dCas9-VP64	positive selection	2554407
171195376	171195399	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAGTCCCAGCTACTCCGG	TLK1	ENSG00000198586	0.2857588864060996	[349,998]	[76,442]	2	dCas9-VP64	positive selection	2563981
171021512	171021535	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCACTTTGGGAGGCAGAGGCCAG	TLK1	ENSG00000198586	4.207282944889167	[182,227]	[2502,59]	9	dCas9-VP64	positive selection	2565297
171160308	171160331	2	+	27013184	SW480	treatment with recombinant TRAIL	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.9585592566136636	[185,172]	[143,160]	4	hSpCas9	positive selection	2966524
171160309	171160332	2	+	27013184	SW480	treatment with recombinant TRAIL	TGGCGGCGTGTGATTCAGCAGGG	TLK1	ENSG00000198586	0.6587579066993097	[336,448]	[187,372]	3	hSpCas9	positive selection	2966525
171066880	171066903	2	+	27013184	SW480	treatment with recombinant TRAIL	CCATTTAGAACAACTGCTGAAGG	TLK1	ENSG00000198586	1.092885017213875	[378,429]	[316,445]	5	hSpCas9	positive selection	2966526
171117761	171117784	2	-	27013184	SW480	treatment with recombinant TRAIL	AGTGGGAGCACTGGAAGTACGGG	TLK1	ENSG00000198586	-0.3423673304688746	[234,126]	[61,64]	-1	hSpCas9	positive selection	2966527
171058153	171058176	2	+	27013184	SW480	treatment with recombinant TRAIL	CAAAATAGTCGCTAATTTTGTGG	TLK1	ENSG00000198586	-1.1198229975306329	[142,135]	[2,62]	-5	hSpCas9	positive selection	2966528
171117762	171117785	2	-	27013184	SW480	treatment with recombinant TRAIL	AAGTGGGAGCACTGGAAGTACGG	TLK1	ENSG00000198586	1.9484212717261757	[26,26]	[32,61]	8	hSpCas9	positive selection	2966529
171117770	171117793	2	-	27013184	SW480	treatment with recombinant TRAIL	GGAGTTGCAAGTGGGAGCACTGG	TLK1	ENSG00000198586	-3.3772535345393653	[81,224]	[8,1]	-9	hSpCas9	positive selection	2966530
171117807	171117830	2	-	27013184	SW480	treatment with recombinant TRAIL	TCCAAGAAGGCAAGAGTTATTGG	TLK1	ENSG00000198586	-0.6704021811072839	[271,323]	[106,41]	-3	hSpCas9	positive selection	2966532
171117820	171117843	2	-	27013184	SW480	treatment with recombinant TRAIL	TTCATAGTCTGGATCCAAGAAGG	TLK1	ENSG00000198586	-5.271776058042072	[232,229]	[2,1]	-9	hSpCas9	positive selection	2966533
171117831	171117854	2	-	27013184	SW480	treatment with recombinant TRAIL	AATGGATGAGCTTCATAGTCTGG	TLK1	ENSG00000198586	-0.8346007872308221	[362,320]	[95,64]	-4	hSpCas9	positive selection	2966534
171061081	171061104	2	-	27013184	SW480	treatment with recombinant TRAIL	AAACCAGAATGAAAGTAGTCAGG	TLK1	ENSG00000198586	0.07976790197939082	[301,279]	[114,158]	0	hSpCas9	positive selection	2966535
171061122	171061145	2	-	27013184	SW480	treatment with recombinant TRAIL	AAACAATCGGAATCATCCAGGGG	TLK1	ENSG00000198586	2.6280335306048612	[12,58]	[64,126]	9	hSpCas9	positive selection	2966536
171160315	171160338	2	+	27013184	SW480	treatment with recombinant TRAIL	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-2.33822394397055	[49,65]	[1,8]	-8	hSpCas9	positive selection	2966537
171066881	171066904	2	+	27013184	SW480	treatment with recombinant TRAIL	CATTTAGAACAACTGCTGAAGGG	TLK1	ENSG00000198586	-0.42248891938460453	[350,309]	[80,143]	-2	hSpCas9	positive selection	2966538
171061123	171061146	2	-	27013184	SW480	treatment with recombinant TRAIL	GAAACAATCGGAATCATCCAGGG	TLK1	ENSG00000198586	-2.259380608935606	[158,114]	[14,8]	-8	hSpCas9	positive selection	2966539
171061124	171061147	2	-	27013184	SW480	treatment with recombinant TRAIL	AGAAACAATCGGAATCATCCAGG	TLK1	ENSG00000198586	2.3255148539564896	[203,156]	[370,428]	8	hSpCas9	positive selection	2966540
171053760	171053783	2	-	27013184	SW480	treatment with recombinant TRAIL	ACGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	-4.442797758635207	[149,41]	[1,1]	-9	hSpCas9	positive selection	2966541
171053761	171053784	2	-	27013184	SW480	treatment with recombinant TRAIL	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	-0.6084266304157662	[595,589]	[124,228]	-3	hSpCas9	positive selection	2966542
171053796	171053819	2	-	27013184	SW480	treatment with recombinant TRAIL	AAGTAATAAAATCCAGGACCTGG	TLK1	ENSG00000198586	-0.4324953949909043	[21,20]	[3,10]	-2	hSpCas9	positive selection	2966544
171160348	171160371	2	+	27013184	SW480	treatment with recombinant TRAIL	CGAGCCCGGGGTTGGAGACGTGG	TLK1	ENSG00000198586	0.07019347204182236	[148,223]	[89,72]	0	hSpCas9	positive selection	2966545
171066884	171066907	2	+	27013184	SW480	treatment with recombinant TRAIL	TTAGAACAACTGCTGAAGGGTGG	TLK1	ENSG00000198586	-2.2947733134536454	[473,587]	[37,57]	-8	hSpCas9	positive selection	2966546
171082815	171082838	2	-	27013184	SW480	treatment with recombinant TRAIL	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-1.879961919366306	[80,71]	[1,18]	-7	hSpCas9	positive selection	2966547
171055130	171055153	2	-	27013184	SW480	treatment with recombinant TRAIL	TCCTACTGCATTAGCATTTGGGG	TLK1	ENSG00000198586	0.321932393577611	[241,175]	[77,165]	1	hSpCas9	positive selection	2966549
171058197	171058220	2	-	27013184	SW480	treatment with recombinant TRAIL	TCATGCGCTTCTTATATTTTAGG	TLK1	ENSG00000198586	1.0729619178136238	[85,144]	[125,68]	5	hSpCas9	positive selection	2966550
171160398	171160421	2	+	27013184	SW480	treatment with recombinant TRAIL	CCAAACTTCCACTGCTACTTTGG	TLK1	ENSG00000198586	-1.4391332642885613	[55,144]	[9,22]	-6	hSpCas9	positive selection	2966551
171160421	171160444	2	+	27013184	SW480	treatment with recombinant TRAIL	ACACTCATCAAGCTACTTTCTGG	TLK1	ENSG00000198586	1.23488658150524	[111,121]	[157,61]	6	hSpCas9	positive selection	2966552
171055129	171055152	2	+	27013184	SW480	treatment with recombinant TRAIL	TCCCCAAATGCTAATGCAGTAGG	TLK1	ENSG00000198586	0.8196513522566936	[285,142]	[232,75]	4	hSpCas9	positive selection	2966553
171160422	171160445	2	+	27013184	SW480	treatment with recombinant TRAIL	CACTCATCAAGCTACTTTCTGGG	TLK1	ENSG00000198586	-0.7034514510485175	[776,977]	[230,228]	-3	hSpCas9	positive selection	2966555
171117806	171117829	2	+	27013184	SW480	treatment with recombinant TRAIL	TCCAATAACTCTTGCCTTCTTGG	TLK1	ENSG00000198586	-0.17444607574822046	[177,464]	[115,120]	0	hSpCas9	positive selection	2966556
171117746	171117769	2	-	27013184	SW480	treatment with recombinant TRAIL	AGTACGGGCAGTTGCAGTGTTGG	TLK1	ENSG00000198586	-1.6691028018704812	[269,375]	[62,14]	-6	hSpCas9	positive selection	2966558
171046334	171046357	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAATGGGTGAATCAGCAAAGGG	TLK1	ENSG00000198586	0.04332152537046442	[3,2]	[3,2]	0	hSpCas9	positive selection	3026984
171053783	171053806	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGGACCTGGAAAAGAAGGAGGG	TLK1	ENSG00000198586	-0.7038210800885352	[3,3]	[2,0]	-8	hSpCas9	positive selection	3026985
171046334	171046357	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAATGGGTGAATCAGCAAAGGG	TLK1	ENSG00000198586	-0.30787548380994	[3,3]	[1,1]	-5	hSpCas9	positive selection	3094842
171053783	171053806	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGGACCTGGAAAAGAAGGAGGG	TLK1	ENSG00000198586	0.32873330169319676	[3,3]	[2,2]	6	hSpCas9	positive selection	3094843
171061081	171061104		-	24336571	A375	resistance to PLX after 7 days	AAACCAGAATGAAAGTAGTCAGG	TLK1	ENSG00000198586	-0.21993543714761266	[8,10]	[8,7]	-6	hSpCas9	positive selection	3150459
171082829	171082852		+	24336571	A375	resistance to PLX after 7 days	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	-0.2803604133625601	[33,31]	[26,26]	-8	hSpCas9	positive selection	3150460
171028395	171028418		-	24336571	A375	resistance to PLX after 7 days	CATTTTTGACAGGTTGACTTTGG	TLK1	ENSG00000198586	0.050734820637217626	[8,8]	[7,9]	1	hSpCas9	positive selection	3150461
171028352	171028375		-	24336571	A375	resistance to PLX after 7 days	GAAATTTTCAAACTTAGACTAGG	TLK1	ENSG00000198586	0.2723806819768795	[1,2]	[2,2]	7	hSpCas9	positive selection	3150462
171061135	171061158		-	24336571	A375	resistance to PLX after 7 days	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.08302413301628225	[9,8]	[8,9]	3	hSpCas9	positive selection	3150463
171061078	171061101		+	24336571	A375	resistance to PLX after 7 days	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.11432119192638002	[69,72]	[75,77]	4	hSpCas9	positive selection	3150464
171082780	171082803		-	24336571	A375	resistance to PLX after 7 days	TTTAAGTGACAAAGAATCAGAGG	TLK1	ENSG00000198586	-0.2049329262519194	[12,18]	[13,12]	-6	hSpCas9	positive selection	3150465
171061081	171061104		-	24336571	A375	resistance to PLX after 14 days	AAACCAGAATGAAAGTAGTCAGG	TLK1	ENSG00000198586	-0.29045167111907255	[8,10]	[3,3]	-3	hSpCas9	positive selection	3208252
171082829	171082852		+	24336571	A375	resistance to PLX after 14 days	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	-0.2882652669268748	[34,29]	[10,12]	-3	hSpCas9	positive selection	3208253
171028395	171028418		-	24336571	A375	resistance to PLX after 14 days	CATTTTTGACAGGTTGACTTTGG	TLK1	ENSG00000198586	0.06403207157043911	[5,11]	[3,3]	0	hSpCas9	positive selection	3208254
171028352	171028375		-	24336571	A375	resistance to PLX after 14 days	GAAATTTTCAAACTTAGACTAGG	TLK1	ENSG00000198586	0.5511330083035402	[1,2]	[1,1]	5	hSpCas9	positive selection	3208255
171061135	171061158		-	24336571	A375	resistance to PLX after 14 days	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.3185549625624255	[8,6]	[4,3]	3	hSpCas9	positive selection	3208256
171061078	171061101		+	24336571	A375	resistance to PLX after 14 days	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.23734414869216103	[76,82]	[42,43]	2	hSpCas9	positive selection	3208257
171082780	171082803		-	24336571	A375	resistance to PLX after 14 days	TTTAAGTGACAAAGAATCAGAGG	TLK1	ENSG00000198586	-0.6305739989236223	[11,22]	[4,3]	-7	hSpCas9	positive selection	3208258
171061081	171061104		-	24336571	A375	viability after 7 days	AAACCAGAATGAAAGTAGTCAGG	TLK1	ENSG00000198586	0.3286984544503042	[7]	[8,10]	5	hSpCas9	negative selection	3266045
171082829	171082852		+	24336571	A375	viability after 7 days	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.6624257502696865	[21]	[33,31]	8	hSpCas9	negative selection	3266046
171028395	171028418		-	24336571	A375	viability after 7 days	CATTTTTGACAGGTTGACTTTGG	TLK1	ENSG00000198586	0.39066436897552487	[6]	[8,8]	6	hSpCas9	negative selection	3266047
171028352	171028375		-	24336571	A375	viability after 7 days	GAAATTTTCAAACTTAGACTAGG	TLK1	ENSG00000198586	-0.8032553712682142	[4]	[1,2]	-8	hSpCas9	negative selection	3266048
171061135	171061158		-	24336571	A375	viability after 7 days	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.6175329334434809	[15]	[9,8]	-7	hSpCas9	negative selection	3266049
171061078	171061101		+	24336571	A375	viability after 7 days	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.04419499030588758	[72]	[69,72]	0	hSpCas9	negative selection	3266050
171082780	171082803		-	24336571	A375	viability after 7 days	TTTAAGTGACAAAGAATCAGAGG	TLK1	ENSG00000198586	-0.37758611528594105	[21]	[12,18]	-5	hSpCas9	negative selection	3266051
171061081	171061104		-	24336571	A375	viability after 14 days	AAACCAGAATGAAAGTAGTCAGG	TLK1	ENSG00000198586	0.37260123192930483	[7]	[8,10]	5	hSpCas9	negative selection	3323838
171082829	171082852		+	24336571	A375	viability after 14 days	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.6612829633216842	[21]	[34,29]	8	hSpCas9	negative selection	3323839
171028395	171028418		-	24336571	A375	viability after 14 days	CATTTTTGACAGGTTGACTTTGG	TLK1	ENSG00000198586	0.41987038255885367	[6]	[5,11]	5	hSpCas9	negative selection	3323840
171028352	171028375		-	24336571	A375	viability after 14 days	GAAATTTTCAAACTTAGACTAGG	TLK1	ENSG00000198586	-0.7978626451314936	[4]	[1,2]	-7	hSpCas9	negative selection	3323841
171061135	171061158		-	24336571	A375	viability after 14 days	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.81411738508139	[15]	[8,6]	-7	hSpCas9	negative selection	3323842
171061078	171061101		+	24336571	A375	viability after 14 days	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.22516482440183028	[72]	[76,82]	3	hSpCas9	negative selection	3323843
171082780	171082803		-	24336571	A375	viability after 14 days	TTTAAGTGACAAAGAATCAGAGG	TLK1	ENSG00000198586	-0.2348537856238841	[21]	[11,22]	-3	hSpCas9	negative selection	3323844
171028377	171028400	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	1.3031299010589596	[61,61]	[0,0]	5	hSpCas9	positive selection	3397332
171082815	171082838	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	1.3746831620839939	[58,58]	[0,0]	6	hSpCas9	positive selection	3397333
171061131	171061154	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	-1.0780641432480897	[322,322]	[0,0]	-7	hSpCas9	positive selection	3397334
171061122	171061145	2	-	26780180	HT29	viability (Avana library 4 designs)	AAACAATCGGAATCATCCAGGGG	TLK1	ENSG00000198586	2.1124137876726	[]	[]	7	hSpCas9	negative selection	3465739
171046334	171046357	2	-	26780180	HT29	viability (Avana library 4 designs)	AGAATGGGTGAATCAGCAAAGGG	TLK1	ENSG00000198586	0.962292131486537	[]	[]	4	hSpCas9	negative selection	3465740
171053783	171053806	2	-	26780180	HT29	viability (Avana library 4 designs)	CAGGACCTGGAAAAGAAGGAGGG	TLK1	ENSG00000198586	2.83915568292004	[]	[]	8	hSpCas9	negative selection	3465741
171046243	171046266	2	+	26780180	HT29	viability (Avana library 4 designs)	TTTGGTTCAGAATTGGTAGAGGG	TLK1	ENSG00000198586	0.1389100509941	[]	[]	0	hSpCas9	negative selection	3465742
171046243	171046266	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGGTTCAGAATTGGTAGAGGG	TLK1	ENSG00000198586	0.789655318457694	[]	[]	1	hSpCas9	negative selection	3569074
171061122	171061145	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAACAATCGGAATCATCCAGGGG	TLK1	ENSG00000198586	-0.16827909389237	[]	[]	0	hSpCas9	negative selection	3569075
171046334	171046357	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAATGGGTGAATCAGCAAAGGG	TLK1	ENSG00000198586	1.19097730088555	[]	[]	1	hSpCas9	negative selection	3569076
171053783	171053806	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGGACCTGGAAAAGAAGGAGGG	TLK1	ENSG00000198586	-0.991939709791232	[]	[]	-1	hSpCas9	negative selection	3569077
171046243	171046266	2	+	26780180	A375	viability (Avana lentiGuide)	TTTGGTTCAGAATTGGTAGAGGG	TLK1	ENSG00000198586	-8.2410148560773	[]	[]	-9	hSpCas9	negative selection	3677733
171061122	171061145	2	-	26780180	A375	viability (Avana lentiGuide)	AAACAATCGGAATCATCCAGGGG	TLK1	ENSG00000198586	-2.76888320644626	[]	[]	-5	hSpCas9	negative selection	3677734
171046334	171046357	2	-	26780180	A375	viability (Avana lentiGuide)	AGAATGGGTGAATCAGCAAAGGG	TLK1	ENSG00000198586	10.4251968957587	[]	[]	7	hSpCas9	negative selection	3677735
171053783	171053806	2	-	26780180	A375	viability (Avana lentiGuide)	CAGGACCTGGAAAAGAAGGAGGG	TLK1	ENSG00000198586	3.49188735605631	[]	[]	3	hSpCas9	negative selection	3677736
171046243	171046266	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGGTTCAGAATTGGTAGAGGG	TLK1	ENSG00000198586	-0.07141445463963392	[6]	[6,5]	-1	hSpCas9	positive selection	3786340
171061122	171061145	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAACAATCGGAATCATCCAGGGG	TLK1	ENSG00000198586	-0.1452889682719048	[4]	[3,5]	-2	hSpCas9	positive selection	3786341
171046334	171046357	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAATGGGTGAATCAGCAAAGGG	TLK1	ENSG00000198586	0.020924429181578993	[5]	[5,4]	0	hSpCas9	positive selection	3786342
171053783	171053806	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGGACCTGGAAAAGAAGGAGGG	TLK1	ENSG00000198586	0.13136228005005035	[4]	[4,4]	3	hSpCas9	positive selection	3786343
171046243	171046266	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGGTTCAGAATTGGTAGAGGG	TLK1	ENSG00000198586	0.3245438787802293	[5]	[5,5]	8	hSpCas9	positive selection	3894947
171061122	171061145	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAACAATCGGAATCATCCAGGGG	TLK1	ENSG00000198586	-0.8124289762374869	[4]	[1,1]	-7	hSpCas9	positive selection	3894948
171046334	171046357	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAATGGGTGAATCAGCAAAGGG	TLK1	ENSG00000198586	0.21908417888995327	[5]	[4,5]	5	hSpCas9	positive selection	3894949
171053783	171053806	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGGACCTGGAAAAGAAGGAGGG	TLK1	ENSG00000198586	0.057584393621321096	[5]	[4,4]	1	hSpCas9	positive selection	3894950
171082829	171082852	2	+	26780180	A375	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.671145843696199	[]	[]	2	hSpCas9	negative selection	4004289
171082815	171082838	2	-	26780180	A375	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	1.15307507722196	[]	[]	6	hSpCas9	negative selection	4004290
171061135	171061158	2	-	26780180	A375	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.342671543509916	[]	[]	0	hSpCas9	negative selection	4004291
171061131	171061154	2	+	26780180	A375	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.226465363301931	[]	[]	0	hSpCas9	negative selection	4004292
171061078	171061101	2	+	26780180	A375	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.139966041646559	[]	[]	0	hSpCas9	negative selection	4004293
171028377	171028400	2	-	26780180	A375	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	0.476350912908349	[]	[]	1	hSpCas9	negative selection	4004294
171082829	171082852	2	+	26780180	HT29	viability (GeCKOv2 library)	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.70921113721368	[]	[]	2	hSpCas9	negative selection	4112255
171082815	171082838	2	-	26780180	HT29	viability (GeCKOv2 library)	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	1.48991985070311	[]	[]	7	hSpCas9	negative selection	4112256
171061135	171061158	2	-	26780180	HT29	viability (GeCKOv2 library)	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.252332386982849	[]	[]	0	hSpCas9	negative selection	4112257
171061131	171061154	2	+	26780180	HT29	viability (GeCKOv2 library)	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.997265301531252	[]	[]	4	hSpCas9	negative selection	4112258
171061078	171061101	2	+	26780180	HT29	viability (GeCKOv2 library)	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	-0.0394656340676039	[]	[]	-1	hSpCas9	negative selection	4112259
171028377	171028400	2	-	26780180	HT29	viability (GeCKOv2 library)	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	1.24053096471782	[]	[]	6	hSpCas9	negative selection	4112260
171061081	171061104	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAACCAGAATGAAAGTAGTCAGG	TLK1	ENSG00000198586	-0.4159057453291478	[3]	[0,1]	-8	hSpCas9	positive selection	4176862
171082829	171082852	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.4506314604281624	[5]	[6,3]	8	hSpCas9	positive selection	4176863
171028395	171028418	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATTTTTGACAGGTTGACTTTGG	TLK1	ENSG00000198586	-0.18600846868314735	[2]	[1,1]	-4	hSpCas9	positive selection	4176864
171028352	171028375	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAATTTTCAAACTTAGACTAGG	TLK1	ENSG00000198586	-0.9241296828147836	[1]	[0,0]	-9	hSpCas9	positive selection	4176865
171061135	171061158	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.16040046564972726	[3]	[2,1]	4	hSpCas9	positive selection	4176866
171061078	171061101	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.27761062986622764	[5]	[4,5]	7	hSpCas9	positive selection	4176867
171082780	171082803	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTAAGTGACAAAGAATCAGAGG	TLK1	ENSG00000198586	-0.02470901686737066	[4]	[2,2]	0	hSpCas9	positive selection	4176868
171061081	171061104	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAACCAGAATGAAAGTAGTCAGG	TLK1	ENSG00000198586	1.7041832350981094	[2]	[3,3,4,2]	9	hSpCas9	positive selection	4240884
171082829	171082852	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.925150171498631	[4]	[2,0,5,3]	6	hSpCas9	positive selection	4240885
171028395	171028418	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATTTTTGACAGGTTGACTTTGG	TLK1	ENSG00000198586	-0.13561589849882688	[4]	[0,2,3,0]	-2	hSpCas9	positive selection	4240886
171028352	171028375	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAATTTTCAAACTTAGACTAGG	TLK1	ENSG00000198586	-0.32467778276504433	[2]	[2,0,0,0]	-5	hSpCas9	positive selection	4240887
171061135	171061158	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.9070018758007504	[4]	[3,3,1,3]	6	hSpCas9	positive selection	4240888
171061078	171061101	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.9722118588996738	[5]	[5,5,6,3]	6	hSpCas9	positive selection	4240889
171082780	171082803	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTAAGTGACAAAGAATCAGAGG	TLK1	ENSG00000198586	0.39943977180362644	[3]	[3,4,3,0]	3	hSpCas9	positive selection	4240890
171061135	171061158	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.010504859375961129	[0]	[0,0]	0	hSpCas9	positive selection	4303243
171082829	171082852	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.345417545272027	[2]	[2,1]	7	hSpCas9	positive selection	4303244
171061078	171061101	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.3470541401606083	[4]	[5,4]	7	hSpCas9	positive selection	4303245
171028377	171028400	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.7407303676296129	[2]	[1,0]	-9	hSpCas9	positive selection	4367496
171082815	171082838	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	0.1679242251255716	[1]	[2,0]	3	hSpCas9	positive selection	4367497
171061131	171061154	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	-0.052276348579629	[3]	[3,1]	-1	hSpCas9	positive selection	4367498
171046181	171046203	2	+	27760321	OCIAML3	viability	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	0.3814094987885004	[21,25]	[25,22]	4	hSpCas9	negative selection	4447211
171049891	171049913	2	-	27760321	OCIAML3	viability	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	-0.3100826423700531	[549,418]	[294,313]	-3	hSpCas9	negative selection	4447212
171053760	171053782	2	-	27760321	OCIAML3	viability	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	0.20221102239018618	[280,232]	[234,223]	2	hSpCas9	negative selection	4447213
171055107	171055129	2	+	27760321	OCIAML3	viability	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	-0.23839220806649908	[193,174]	[139,98]	-3	hSpCas9	negative selection	4447214
171055136	171055158	2	+	27760321	OCIAML3	viability	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	-0.2386278191078608	[107,84]	[53,75]	-3	hSpCas9	negative selection	4447215
171046181	171046203	2	+	27760321	OCIAML2	viability	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	-0.6442880208181387	[21,25]	[15,7]	-6	hSpCas9	negative selection	4530674
171049891	171049913	2	-	27760321	OCIAML2	viability	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	-0.5295844667616441	[549,418]	[252,290]	-5	hSpCas9	negative selection	4530675
171053760	171053782	2	-	27760321	OCIAML2	viability	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	-0.8273741287518075	[280,232]	[104,131]	-7	hSpCas9	negative selection	4530676
171055107	171055129	2	+	27760321	OCIAML2	viability	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	0.283811356245972	[193,174]	[124,255]	4	hSpCas9	negative selection	4530677
171055136	171055158	2	+	27760321	OCIAML2	viability	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	0.4726936285031855	[107,84]	[57,172]	6	hSpCas9	negative selection	4530678
171046181	171046203	2	+	27760321	MV411	viability	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	-3.999817174629519	[21,25]	[0,0]	-9	hSpCas9	negative selection	4614137
171049891	171049913	2	-	27760321	MV411	viability	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	0.4647682735306182	[549,418]	[436,438]	3	hSpCas9	negative selection	4614138
171053760	171053782	2	-	27760321	MV411	viability	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	-0.12333189924964416	[280,232]	[174,124]	-1	hSpCas9	negative selection	4614139
171055107	171055129	2	+	27760321	MV411	viability	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	0.2373099164830368	[193,174]	[124,170]	1	hSpCas9	negative selection	4614140
171055136	171055158	2	+	27760321	MV411	viability	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	-0.18235481048073687	[107,84]	[0,137]	-1	hSpCas9	negative selection	4614141
171046181	171046203	2	+	27760321	HL60	viability	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	0.6784760288432707	[21,25]	[4,59]	7	hSpCas9	negative selection	4697600
171049891	171049913	2	-	27760321	HL60	viability	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	-0.20913353945527233	[549,418]	[428,244]	-2	hSpCas9	negative selection	4697601
171053760	171053782	2	-	27760321	HL60	viability	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	-0.04342410681335451	[280,232]	[229,173]	0	hSpCas9	negative selection	4697602
171055107	171055129	2	+	27760321	HL60	viability	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	-0.4912622194010161	[193,174]	[110,102]	-5	hSpCas9	negative selection	4697603
171055136	171055158	2	+	27760321	HL60	viability	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	-1.884908883338258	[107,84]	[27,13]	-9	hSpCas9	negative selection	4697604
171046181	171046203	2	+	27760321	HT1080	viability	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	-0.8248882839081042	[25,20]	[0,9]	-3	hSpCas9	negative selection	4781063
171049891	171049913	2	-	27760321	HT1080	viability	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	0.4566229487978508	[418,326]	[159,251]	2	hSpCas9	negative selection	4781064
171053760	171053782	2	-	27760321	HT1080	viability	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	-0.06977770921718185	[232,181]	[136,14]	0	hSpCas9	negative selection	4781065
171055107	171055129	2	+	27760321	HT1080	viability	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	-2.8472230034894284	[174,136]	[0,16]	-7	hSpCas9	negative selection	4781066
171055136	171055158	2	+	27760321	HT1080	viability	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	-0.1147181750816828	[84,66]	[16,39]	0	hSpCas9	negative selection	4781067
171046181	171046203	2	+	27760321	HT29	viability after 7 days	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	-2.5262039982194584	[25,20]	[0,3,9]	-9	hSpCas9	negative selection	4864526
171049891	171049913	2	-	27760321	HT29	viability after 7 days	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	0.04998914056007503	[418,326]	[302,752,407]	0	hSpCas9	negative selection	4864527
171053760	171053782	2	-	27760321	HT29	viability after 7 days	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	-0.045385819859703136	[232,181]	[300,148,328]	0	hSpCas9	negative selection	4864528
171055107	171055129	2	+	27760321	HT29	viability after 7 days	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	-0.5747116169404709	[174,136]	[91,113,189]	-7	hSpCas9	negative selection	4864529
171055136	171055158	2	+	27760321	HT29	viability after 7 days	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	0.46689669303252357	[84,66]	[132,234,39]	7	hSpCas9	negative selection	4864530
171046181	171046203	2	+	27760321	HT29	viability after 25 days	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	1.159161530278229	[25,20]	[54,95,25]	9	hSpCas9	negative selection	4947989
171049891	171049913	2	-	27760321	HT29	viability after 25 days	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	-0.035158315495934025	[418,326]	[407,491,339]	0	hSpCas9	negative selection	4947990
171053760	171053782	2	-	27760321	HT29	viability after 25 days	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	-0.14181472210286583	[232,181]	[258,199,178]	-1	hSpCas9	negative selection	4947991
171055107	171055129	2	+	27760321	HT29	viability after 25 days	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	-0.31226045401319813	[174,136]	[90,146,201]	-3	hSpCas9	negative selection	4947992
171055136	171055158	2	+	27760321	HT29	viability after 25 days	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	0.30052413200401573	[84,66]	[171,70,69]	3	hSpCas9	negative selection	4947993
171046181	171046203	2	+	27760321	HT29	viability after 22 days	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	-1.188673698816229	[25,20]	[4,20,9]	-7	hSpCas9	negative selection	5031452
171049891	171049913	2	-	27760321	HT29	viability after 22 days	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	-0.0013520381763336836	[418,326]	[380,453,458]	0	hSpCas9	negative selection	5031453
171053760	171053782	2	-	27760321	HT29	viability after 22 days	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	-0.6182915817636029	[232,181]	[150,157,159]	-5	hSpCas9	negative selection	5031454
171055107	171055129	2	+	27760321	HT29	viability after 22 days	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	-0.519145481192947	[174,136]	[78,158,140]	-5	hSpCas9	negative selection	5031455
171055136	171055158	2	+	27760321	HT29	viability after 22 days	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	0.3819479453905359	[84,66]	[107,105,129]	4	hSpCas9	negative selection	5031456
171046181	171046203	2	+	27760321	HT29	viability after 19 days	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	-0.1839539673584496	[25,20]	[61,12,0]	-2	hSpCas9	negative selection	5114915
171049891	171049913	2	-	27760321	HT29	viability after 19 days	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	-0.31119965283792383	[418,326]	[366,492,179]	-3	hSpCas9	negative selection	5114916
171053760	171053782	2	-	27760321	HT29	viability after 19 days	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	0.7389323012565784	[232,181]	[242,158,755]	7	hSpCas9	negative selection	5114917
171055107	171055129	2	+	27760321	HT29	viability after 19 days	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	-0.6719338845912093	[174,136]	[85,182,65]	-5	hSpCas9	negative selection	5114918
171055136	171055158	2	+	27760321	HT29	viability after 19 days	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	0.15582419973037753	[84,66]	[138,138,19]	1	hSpCas9	negative selection	5114919
171046181	171046203	2	+	27760321	HT29	viability after 16 days	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	0.3412166286159275	[25,20]	[2,4,89]	4	hSpCas9	negative selection	5198378
171049891	171049913	2	-	27760321	HT29	viability after 16 days	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	0.21297374085277318	[418,326]	[268,549,609]	2	hSpCas9	negative selection	5198379
171053760	171053782	2	-	27760321	HT29	viability after 16 days	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	0.32546945687423945	[232,181]	[118,461,270]	3	hSpCas9	negative selection	5198380
171055107	171055129	2	+	27760321	HT29	viability after 16 days	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	-0.07794884602897811	[174,136]	[108,310,66]	-1	hSpCas9	negative selection	5198381
171055136	171055158	2	+	27760321	HT29	viability after 16 days	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	0.2859015415343251	[84,66]	[86,87,134]	3	hSpCas9	negative selection	5198382
171046181	171046203	2	+	27760321	HT29	viability after 13 days	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	0.3010882989019623	[25,20]	[40,26,32]	4	hSpCas9	negative selection	5281841
171049891	171049913	2	-	27760321	HT29	viability after 13 days	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	-0.1698078205490034	[418,326]	[300,380,466]	-2	hSpCas9	negative selection	5281842
171053760	171053782	2	-	27760321	HT29	viability after 13 days	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	-0.7227294827900276	[232,181]	[202,165,72]	-6	hSpCas9	negative selection	5281843
171055107	171055129	2	+	27760321	HT29	viability after 13 days	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	-0.7151679251568519	[174,136]	[92,147,90]	-6	hSpCas9	negative selection	5281844
171055136	171055158	2	+	27760321	HT29	viability after 13 days	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	0.9767918941835068	[84,66]	[309,95,117]	9	hSpCas9	negative selection	5281845
171046181	171046203	2	+	27760321	HT29	viability after 10 days	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	-0.21085474434238938	[25,20]	[27,19,27]	-3	hSpCas9	negative selection	5365304
171049891	171049913	2	-	27760321	HT29	viability after 10 days	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	-0.09097816748343854	[418,326]	[226,597,489]	-1	hSpCas9	negative selection	5365305
171053760	171053782	2	-	27760321	HT29	viability after 10 days	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	-0.552047055184543	[232,181]	[181,71,270]	-6	hSpCas9	negative selection	5365306
171055107	171055129	2	+	27760321	HT29	viability after 10 days	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	-0.4535924633292905	[174,136]	[140,167,118]	-5	hSpCas9	negative selection	5365307
171055136	171055158	2	+	27760321	HT29	viability after 10 days	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	0.3339713822712109	[84,66]	[155,102,99]	4	hSpCas9	negative selection	5365308
171046181	171046203	2	+	27760321	MOLM13	viability	GTAAATTTGGTCTAACAAAGGG	TLK1	ENSG00000198586	-1.0953263798795332	[21,25]	[0,10]	-6	hSpCas9	negative selection	5448767
171049891	171049913	2	-	27760321	MOLM13	viability	GCAAGATCGATTACGCCTCGGG	TLK1	ENSG00000198586	1.0304099185175981	[549,418]	[997,175]	7	hSpCas9	negative selection	5448768
171053760	171053782	2	-	27760321	MOLM13	viability	CGTATAGATGATTTGCTCAGGG	TLK1	ENSG00000198586	-1.6998399415345646	[280,232]	[51,37]	-7	hSpCas9	negative selection	5448769
171055107	171055129	2	+	27760321	MOLM13	viability	CTTTGGTTGTACAATAGGGTGG	TLK1	ENSG00000198586	-1.744503533979942	[193,174]	[43,19]	-7	hSpCas9	negative selection	5448770
171055136	171055158	2	+	27760321	MOLM13	viability	ATGCTAATGCAGTAGGAGAAGG	TLK1	ENSG00000198586	1.1814960798193221	[107,84]	[173,78]	8	hSpCas9	negative selection	5448771
171160467	171160490	2	+	27661255	K562	viability	GGCAGCGGCGGCAACGGCACCGG	TLK1	ENSG00000198586	-0.00023570776176795594	[879,1042]	[838,702]	0	dCas9-KRAB	negative selection	5517507
171160569	171160592	2	+	27661255	K562	viability	GGGGAGGAAACCGAGAAGAGGGG	TLK1	ENSG00000198586	-0.6359080689591703	[1096,1293]	[629,597]	-8	dCas9-KRAB	negative selection	5517508
171160572	171160595	2	+	27661255	K562	viability	GAGGAAACCGAGAAGAGGGGAGG	TLK1	ENSG00000198586	0.3006668791457697	[265,658]	[446,448]	8	dCas9-KRAB	negative selection	5517509
171160657	171160680	2	+	27661255	K562	viability	GGAGCGAGCGGGCGCGCCAGAGG	TLK1	ENSG00000198586	-0.09304534891149074	[534,577]	[433,400]	-3	dCas9-KRAB	negative selection	5517510
171160948	171160971	2	+	27661255	K562	viability	GGCTCCTGCGCCTCCGGTAGCGG	TLK1	ENSG00000198586	0.09701295105226282	[283,219]	[225,207]	3	dCas9-KRAB	negative selection	5517511
171061135	171061158	2	-	27260156	BXPC3	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.4433875482691021	[34]	[54,45,49,46]	8	hSpCas9	negative selection	5575703
171082829	171082852	2	+	27260156	BXPC3	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.43363532322120524	[264]	[275,339,483,413]	8	hSpCas9	negative selection	5575704
171061078	171061101	2	+	27260156	BXPC3	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.42532430791652054	[1803]	[2191,2561,2681,2741]	8	hSpCas9	negative selection	5575705
171028377	171028400	2	-	27260156	BXPC3	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.35022826044099276	[251]	[206,166,225,230]	-7	hSpCas9	negative selection	5639956
171082815	171082838	2	-	27260156	BXPC3	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.3437070610615607	[145]	[115,115,113,136]	-6	hSpCas9	negative selection	5639957
171061131	171061154	2	+	27260156	BXPC3	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.13848231543624673	[590]	[588,569,611,999]	3	hSpCas9	negative selection	5639958
171061135	171061158	2	-	27260156	A673	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.7297093826356735	[34]	[89,58,37,95]	9	hSpCas9	negative selection	5696954
171082829	171082852	2	+	27260156	A673	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.49594530913980933	[264]	[420,496,419,451]	9	hSpCas9	negative selection	5696955
171061078	171061101	2	+	27260156	A673	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.5516817043961124	[1803]	[3467,3003,3071,3189]	9	hSpCas9	negative selection	5696956
171028377	171028400	2	-	27260156	A673	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.3911973573640377	[251]	[215,221,189,296]	-7	hSpCas9	negative selection	5761207
171082815	171082838	2	-	27260156	A673	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.26953261861708455	[145]	[137,117,120,207]	-6	hSpCas9	negative selection	5761208
171061131	171061154	2	+	27260156	A673	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.31827838903295413	[590]	[1061,803,731,967]	7	hSpCas9	negative selection	5761209
171061135	171061158	2	-	27260156	A375	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.977954150883305	[34]	[54,152,110,19]	9	hSpCas9	negative selection	5818205
171082829	171082852	2	+	27260156	A375	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.6018120995735392	[264]	[418,565,415,486]	8	hSpCas9	negative selection	5818206
171061078	171061101	2	+	27260156	A375	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.7900055377271409	[1803]	[3713,4350,3182,3434]	9	hSpCas9	negative selection	5818207
171028377	171028400	2	-	27260156	A375	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	0.31429576894530264	[251]	[217,236,414,550]	4	hSpCas9	negative selection	5882458
171082815	171082838	2	-	27260156	A375	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	0.49257082508443806	[145]	[197,351,266,165]	7	hSpCas9	negative selection	5882459
171061131	171061154	2	+	27260156	A375	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.6026306272650639	[590]	[847,1070,1062,1190]	8	hSpCas9	negative selection	5882460
171061135	171061158	2	-	27260156	COLO741	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.2566142382989751	[34]	[78,39,43]	5	hSpCas9	negative selection	5939456
171082829	171082852	2	+	27260156	COLO741	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.3349261841723312	[264]	[441,530,316]	7	hSpCas9	negative selection	5939457
171061078	171061101	2	+	27260156	COLO741	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.5810654606225167	[1803]	[3575,3597,3192]	9	hSpCas9	negative selection	5939458
171028377	171028400	2	-	27260156	COLO741	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.19128753728934855	[251]	[372,282,202]	-4	hSpCas9	negative selection	6003709
171082815	171082838	2	-	27260156	COLO741	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.02683035230947839	[145]	[277,98,179]	0	hSpCas9	negative selection	6003710
171061131	171061154	2	+	27260156	COLO741	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.3706869534720676	[590]	[964,1110,858]	7	hSpCas9	negative selection	6003711
171061135	171061158	2	-	27260156	CAL120	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.09388085189851791	[34]	[38,35,62]	1	hSpCas9	negative selection	6060707
171082829	171082852	2	+	27260156	CAL120	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.6981948963465714	[264]	[571,590,448]	8	hSpCas9	negative selection	6060708
171061078	171061101	2	+	27260156	CAL120	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.4728958355224244	[1803]	[3160,3049,3140]	7	hSpCas9	negative selection	6060709
171028377	171028400	2	-	27260156	CAL120	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.4547837376305497	[251]	[268,230,192]	-6	hSpCas9	negative selection	6124960
171082815	171082838	2	-	27260156	CAL120	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-1.2131969819502364	[145]	[98,107,31]	-9	hSpCas9	negative selection	6124961
171061131	171061154	2	+	27260156	CAL120	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.398194753886539	[590]	[991,914,1002]	6	hSpCas9	negative selection	6124962
171061135	171061158	2	-	27260156	CADOES1	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.6721327423939027	[34]	[89,69,31,13]	9	hSpCas9	negative selection	6181958
171082829	171082852	2	+	27260156	CADOES1	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.6546032254808352	[264]	[325,421,368,436]	9	hSpCas9	negative selection	6181959
171061078	171061101	2	+	27260156	CADOES1	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.6526012934313283	[1803]	[2773,2367,2698,2710]	9	hSpCas9	negative selection	6181960
171028377	171028400	2	-	27260156	CADOES1	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.3489683886167907	[251]	[153,113,257,210]	-6	hSpCas9	negative selection	6246211
171082815	171082838	2	-	27260156	CADOES1	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.7777679235102644	[145]	[127,35,62,89]	-8	hSpCas9	negative selection	6246212
171061131	171061154	2	+	27260156	CADOES1	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.31512509525266186	[590]	[632,406,803,898]	5	hSpCas9	negative selection	6246213
171061135	171061158	2	-	27260156	EWS502	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.37302646987637145	[34]	[19,35,0,59]	-6	hSpCas9	negative selection	6303209
171082829	171082852	2	+	27260156	EWS502	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.34602941246446467	[264]	[289,273,283,605]	6	hSpCas9	negative selection	6303210
171061078	171061101	2	+	27260156	EWS502	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.7458047534407535	[1803]	[3076,2697,3091,4030]	9	hSpCas9	negative selection	6303211
171028377	171028400	2	-	27260156	EWS502	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.5924076811961614	[251]	[202,170,155,173]	-7	hSpCas9	negative selection	6367462
171082815	171082838	2	-	27260156	EWS502	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	0.2928301058035583	[145]	[107,345,75,231]	5	hSpCas9	negative selection	6367463
171061131	171061154	2	+	27260156	EWS502	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.3934003428927837	[590]	[848,835,679,921]	7	hSpCas9	negative selection	6367464
171061135	171061158	2	-	27260156	EW8	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.8041449821158704	[34]	[14,50,79,42]	9	hSpCas9	negative selection	6424460
171082829	171082852	2	+	27260156	EW8	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.6531947952126417	[264]	[411,360,256,341]	9	hSpCas9	negative selection	6424461
171061078	171061101	2	+	27260156	EW8	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.6186647266611205	[1803]	[2661,2101,1858,2459]	9	hSpCas9	negative selection	6424462
171028377	171028400	2	-	27260156	EW8	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.3333873821072033	[251]	[200,103,202,136]	-6	hSpCas9	negative selection	6488713
171082815	171082838	2	-	27260156	EW8	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.08079777479495731	[145]	[215,79,43,129]	-1	hSpCas9	negative selection	6488714
171061131	171061154	2	+	27260156	EW8	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.41313285129913124	[590]	[673,605,703,557]	7	hSpCas9	negative selection	6488715
171061135	171061158	2	-	27260156	CORL105	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.1956003395067798	[34]	[37,13,44,47]	-4	hSpCas9	negative selection	6545711
171082829	171082852	2	+	27260156	CORL105	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.09537628173989676	[264]	[374,311,283,348]	1	hSpCas9	negative selection	6545712
171061078	171061101	2	+	27260156	CORL105	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.47993838872585304	[1803]	[3044,2632,3492,2705]	8	hSpCas9	negative selection	6545713
171028377	171028400	2	-	27260156	CORL105	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.9567982737397644	[251]	[188,118,177,127]	-9	hSpCas9	negative selection	6609964
171082815	171082838	2	-	27260156	CORL105	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.5051569031179446	[145]	[87,111,116,162]	-7	hSpCas9	negative selection	6609965
171061131	171061154	2	+	27260156	CORL105	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	-0.10424748367185585	[590]	[707,580,569,706]	-2	hSpCas9	negative selection	6609966
171061135	171061158	2	-	27260156	HS294T	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.06121101696305642	[34]	[11,2,27,13]	0	hSpCas9	negative selection	6666962
171082829	171082852	2	+	27260156	HS294T	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.3020290339517483	[264]	[112,90,133,177]	4	hSpCas9	negative selection	6666963
171061078	171061101	2	+	27260156	HS294T	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.3614082286852507	[1803]	[844,899,750,1128]	5	hSpCas9	negative selection	6666964
171028377	171028400	2	-	27260156	HS294T	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.497556259893452	[251]	[45,70,66,98]	-6	hSpCas9	negative selection	6731215
171082815	171082838	2	-	27260156	HS294T	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	0.16510203628910247	[145]	[71,74,49,52]	2	hSpCas9	negative selection	6731216
171061131	171061154	2	+	27260156	HS294T	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.17730882242951318	[590]	[166,259,268,362]	2	hSpCas9	negative selection	6731217
171061135	171061158	2	-	27260156	HCC44	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.5907220724812943	[34]	[150,3,29,63]	8	hSpCas9	negative selection	6788213
171082829	171082852	2	+	27260156	HCC44	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.2674160590755872	[264]	[530,282,285,353]	4	hSpCas9	negative selection	6788214
171061078	171061101	2	+	27260156	HCC44	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.5831488546703572	[1803]	[3170,2373,3477,3348]	8	hSpCas9	negative selection	6788215
171028377	171028400	2	-	27260156	HCC44	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.09550049771500391	[251]	[363,156,400,192]	-1	hSpCas9	negative selection	6852466
171082815	171082838	2	-	27260156	HCC44	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	0.33504047821837535	[145]	[273,243,209,107]	5	hSpCas9	negative selection	6852467
171061131	171061154	2	+	27260156	HCC44	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.37215253131771764	[590]	[777,888,1293,564]	6	hSpCas9	negative selection	6852468
171061135	171061158	2	-	27260156	G402	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.4790807715448695	[34]	[110,50,5,75]	6	hSpCas9	negative selection	6909464
171082829	171082852	2	+	27260156	G402	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	1.099243704233532	[264]	[1056,682,421,659]	9	hSpCas9	negative selection	6909465
171061078	171061101	2	+	27260156	G402	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.8710141110504113	[1803]	[3943,4004,4372,3765]	9	hSpCas9	negative selection	6909466
171028377	171028400	2	-	27260156	G402	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	0.16017205973115312	[251]	[63,807,129,356]	2	hSpCas9	negative selection	6973717
171082815	171082838	2	-	27260156	G402	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.011642549941483393	[145]	[63,97,381,142]	0	hSpCas9	negative selection	6973718
171061131	171061154	2	+	27260156	G402	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.30571298941703484	[590]	[904,529,921,1171]	4	hSpCas9	negative selection	6973719
171061135	171061158	2	-	27260156	L33	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.02299449946578358	[34]	[38,13,29,16]	0	hSpCas9	negative selection	7030715
171082829	171082852	2	+	27260156	L33	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.28908426898635575	[264]	[289,118,179,427]	6	hSpCas9	negative selection	7030716
171061078	171061101	2	+	27260156	L33	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.16014516382191735	[1803]	[1909,800,1277,2165]	3	hSpCas9	negative selection	7030717
171028377	171028400	2	-	27260156	L33	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.3033762742843642	[251]	[258,92,128,124]	-6	hSpCas9	negative selection	7094968
171082815	171082838	2	-	27260156	L33	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.1909879385783555	[145]	[82,42,98,166]	-4	hSpCas9	negative selection	7094969
171061131	171061154	2	+	27260156	L33	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	-0.03397736903087356	[590]	[580,252,329,584]	0	hSpCas9	negative selection	7094970
171061135	171061158	2	-	27260156	K562	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.7232144894015682	[34]	[19,3,26,22]	-7	hSpCas9	negative selection	7151966
171082829	171082852	2	+	27260156	K562	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.26767966394648635	[264]	[205,229,297,376]	3	hSpCas9	negative selection	7151967
171061078	171061101	2	+	27260156	K562	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.8253829160542656	[1803]	[2485,3587,3161,2186]	9	hSpCas9	negative selection	7151968
171028377	171028400	2	-	27260156	K562	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.5903554423307429	[251]	[118,207,229,48]	-6	hSpCas9	negative selection	7216219
171082815	171082838	2	-	27260156	K562	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	0.38220117060100334	[145]	[178,141,295,68]	5	hSpCas9	negative selection	7216220
171061131	171061154	2	+	27260156	K562	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.08745251084711675	[590]	[536,596,610,489]	1	hSpCas9	negative selection	7216221
171061135	171061158	2	-	27260156	HT29	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.2459944991160139	[34]	[36,44,40,73]	5	hSpCas9	negative selection	7273217
171082829	171082852	2	+	27260156	HT29	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.21530885261593513	[264]	[409,539,273,295]	4	hSpCas9	negative selection	7273218
171061078	171061101	2	+	27260156	HT29	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.5484594565078162	[1803]	[3632,3488,3129,2676]	9	hSpCas9	negative selection	7273219
171028377	171028400	2	-	27260156	HT29	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.9143554927612496	[251]	[134,237,114,164]	-8	hSpCas9	negative selection	7337470
171082815	171082838	2	-	27260156	HT29	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.5721301902098916	[145]	[67,97,123,173]	-7	hSpCas9	negative selection	7337471
171061131	171061154	2	+	27260156	HT29	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.07861849917784719	[590]	[783,750,786,713]	1	hSpCas9	negative selection	7337472
171061135	171061158	2	-	27260156	MHHES1	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	1.277089319460214	[34]	[97,192,35,68]	9	hSpCas9	negative selection	7394468
171082829	171082852	2	+	27260156	MHHES1	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.5141950114518847	[264]	[528,470,334,385]	8	hSpCas9	negative selection	7394469
171061078	171061101	2	+	27260156	MHHES1	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.6301905065431428	[1803]	[4476,3464,2751,2221]	9	hSpCas9	negative selection	7394470
171028377	171028400	2	-	27260156	MHHES1	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.22217408725153054	[251]	[226,229,418,118]	-4	hSpCas9	negative selection	7458721
171082815	171082838	2	-	27260156	MHHES1	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.8321108249206193	[145]	[21,167,81,93]	-9	hSpCas9	negative selection	7458722
171061131	171061154	2	+	27260156	MHHES1	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.052718224709999706	[590]	[680,775,779,549]	1	hSpCas9	negative selection	7458723
171061135	171061158	2	-	27260156	MEWO	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.5527230910064209	[34]	[47,63,31]	9	hSpCas9	negative selection	7515719
171082829	171082852	2	+	27260156	MEWO	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.05494204559191118	[264]	[192,273,292]	1	hSpCas9	negative selection	7515720
171061078	171061101	2	+	27260156	MEWO	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.42085953180058233	[1803]	[2787,2097,1994]	8	hSpCas9	negative selection	7515721
171028377	171028400	2	-	27260156	MEWO	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.8884652785063967	[251]	[116,133,128]	-9	hSpCas9	negative selection	7579972
171082815	171082838	2	-	27260156	MEWO	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.2481368992413442	[145]	[98,93,148]	-5	hSpCas9	negative selection	7579973
171061131	171061154	2	+	27260156	MEWO	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.18893424836456174	[590]	[783,524,611]	4	hSpCas9	negative selection	7579974
171061135	171061158	2	-	27260156	LNCAPCLONEFGC	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.6979615736930227	[34]	[52,31,71,52]	9	hSpCas9	negative selection	7636970
171082829	171082852	2	+	27260156	LNCAPCLONEFGC	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.41807064933207616	[264]	[430,174,372,318]	6	hSpCas9	negative selection	7636971
171061078	171061101	2	+	27260156	LNCAPCLONEFGC	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.7032394400103765	[1803]	[3008,2202,3102,2414]	9	hSpCas9	negative selection	7636972
171028377	171028400	2	-	27260156	LNCAPCLONEFGC	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.667453587388185	[251]	[99,113,152,211]	-7	hSpCas9	negative selection	7701223
171082815	171082838	2	-	27260156	LNCAPCLONEFGC	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	0.22153872015545395	[145]	[235,193,69,99]	3	hSpCas9	negative selection	7701224
171061131	171061154	2	+	27260156	LNCAPCLONEFGC	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.45881520503811	[590]	[852,541,760,800]	7	hSpCas9	negative selection	7701225
171061135	171061158	2	-	27260156	PANC0327	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	1.1674810356540855	[34]	[29,123,35,78]	9	hSpCas9	negative selection	7758221
171082829	171082852	2	+	27260156	PANC0327	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.08440345298645058	[264]	[263,275,222,232]	1	hSpCas9	negative selection	7758222
171061078	171061101	2	+	27260156	PANC0327	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.5207550889787842	[1803]	[2456,2361,2388,1992]	7	hSpCas9	negative selection	7758223
171028377	171028400	2	-	27260156	PANC0327	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-1.077423441788046	[251]	[130,61,106,131]	-8	hSpCas9	negative selection	7822474
171082815	171082838	2	-	27260156	PANC0327	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.2862680277227867	[145]	[173,66,101,92]	-4	hSpCas9	negative selection	7822475
171061131	171061154	2	+	27260156	PANC0327	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.22095932787347639	[590]	[685,531,733,511]	3	hSpCas9	negative selection	7822476
171061135	171061158	2	-	27260156	NCIH2009	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.06143720218969673	[34]	[124,29,12]	0	hSpCas9	negative selection	7879472
171082829	171082852	2	+	27260156	NCIH2009	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.08833574855295023	[264]	[517,326,360]	1	hSpCas9	negative selection	7879473
171061078	171061101	2	+	27260156	NCIH2009	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.5809715194097858	[1803]	[4443,3304,3696]	7	hSpCas9	negative selection	7879474
171028377	171028400	2	-	27260156	NCIH2009	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.6917155865124327	[251]	[268,143,251]	-7	hSpCas9	negative selection	7943725
171082815	171082838	2	-	27260156	NCIH2009	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.4874128945677143	[145]	[117,190,120]	-6	hSpCas9	negative selection	7943726
171061131	171061154	2	+	27260156	NCIH2009	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	-0.028510054129216977	[590]	[849,605,982]	0	hSpCas9	negative selection	7943727
171061135	171061158	2	-	27260156	NCIH1373	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.7300397106292364	[34]	[17,18,47,1]	-6	hSpCas9	negative selection	8000723
171082829	171082852	2	+	27260156	NCIH1373	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.7757340035922158	[264]	[331,437,369,235]	7	hSpCas9	negative selection	8000724
171061078	171061101	2	+	27260156	NCIH1373	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.8782706131493052	[1803]	[4508,2601,3219,1271]	8	hSpCas9	negative selection	8000725
171028377	171028400	2	-	27260156	NCIH1373	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.8877256088927976	[251]	[68,123,220,48]	-7	hSpCas9	negative selection	8064976
171082815	171082838	2	-	27260156	NCIH1373	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.3157281141622461	[145]	[88,186,159,18]	-3	hSpCas9	negative selection	8064977
171061131	171061154	2	+	27260156	NCIH1373	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.02222870969488988	[590]	[1172,448,546,162]	0	hSpCas9	negative selection	8064978
171061135	171061158	2	-	27260156	PATU8902	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.3978417978785913	[34]	[17,30,139,45]	4	hSpCas9	negative selection	8121974
171082829	171082852	2	+	27260156	PATU8902	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	1.0328468501332895	[264]	[947,728,805,482]	9	hSpCas9	negative selection	8121975
171061078	171061101	2	+	27260156	PATU8902	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.8699391057084025	[1803]	[4854,5947,3177,4733]	8	hSpCas9	negative selection	8121976
171028377	171028400	2	-	27260156	PATU8902	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	0.1341158985443509	[251]	[266,686,340,238]	1	hSpCas9	negative selection	8186227
171082815	171082838	2	-	27260156	PATU8902	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.19628686135673812	[145]	[192,218,29,321]	-2	hSpCas9	negative selection	8186228
171061131	171061154	2	+	27260156	PATU8902	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.2543896459114189	[590]	[1132,1192,896,680]	2	hSpCas9	negative selection	8186229
171061135	171061158	2	-	27260156	PANC1	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.12330782642081228	[34]	[40,3,39,20]	-2	hSpCas9	negative selection	8243225
171082829	171082852	2	+	27260156	PANC1	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.5459923516970532	[264]	[347,331,349,298]	8	hSpCas9	negative selection	8243226
171061078	171061101	2	+	27260156	PANC1	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.7534571045652547	[1803]	[2306,3025,3001,2228]	9	hSpCas9	negative selection	8243227
171028377	171028400	2	-	27260156	PANC1	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.45697835439347956	[251]	[205,154,126,140]	-6	hSpCas9	negative selection	8307478
171082815	171082838	2	-	27260156	PANC1	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.11617623743830752	[145]	[156,139,101,72]	-2	hSpCas9	negative selection	8307479
171061131	171061154	2	+	27260156	PANC1	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.41019587990480233	[590]	[631,830,778,506]	6	hSpCas9	negative selection	8307480
171061135	171061158	2	-	27260156	PANC0813	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.8001088729816299	[34]	[103,18,36,125]	9	hSpCas9	negative selection	8364476
171082829	171082852	2	+	27260156	PANC0813	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.3404534302598993	[264]	[457,450,360,315]	5	hSpCas9	negative selection	8364477
171061078	171061101	2	+	27260156	PANC0813	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.49036606150871576	[1803]	[3390,2968,3083,2522]	7	hSpCas9	negative selection	8364478
171028377	171028400	2	-	27260156	PANC0813	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.5202496165832076	[251]	[255,245,165,163]	-7	hSpCas9	negative selection	8428729
171082815	171082838	2	-	27260156	PANC0813	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.47276161183747933	[145]	[181,113,125,79]	-6	hSpCas9	negative selection	8428730
171061131	171061154	2	+	27260156	PANC0813	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	-0.20965823880528936	[590]	[644,671,489,596]	-3	hSpCas9	negative selection	8428731
171061135	171061158	2	-	27260156	RDES	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.2578415563185841	[34]	[64,57,23,35]	4	hSpCas9	negative selection	8485727
171082829	171082852	2	+	27260156	RDES	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.4485320660176829	[264]	[313,328,436,636]	7	hSpCas9	negative selection	8485728
171061078	171061101	2	+	27260156	RDES	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.6768295687802355	[1803]	[2766,2885,3624,4193]	9	hSpCas9	negative selection	8485729
171028377	171028400	2	-	27260156	RDES	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.46289276056864703	[251]	[107,215,231,318]	-7	hSpCas9	negative selection	8549980
171082815	171082838	2	-	27260156	RDES	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.10682119846073945	[145]	[124,144,110,259]	-2	hSpCas9	negative selection	8549981
171061131	171061154	2	+	27260156	RDES	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.29799829235901354	[590]	[698,735,932,1019]	5	hSpCas9	negative selection	8549982
171061135	171061158	2	-	27260156	PC3	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.3510010007662383	[34]	[10,30,64,21]	-7	hSpCas9	negative selection	8606978
171082829	171082852	2	+	27260156	PC3	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.20713567620966244	[264]	[220,350,321,332]	4	hSpCas9	negative selection	8606979
171061078	171061101	2	+	27260156	PC3	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.48355620843009417	[1803]	[1434,2087,4716,2970]	8	hSpCas9	negative selection	8606980
171028377	171028400	2	-	27260156	PC3	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.10177978819415334	[251]	[130,282,297,271]	-2	hSpCas9	negative selection	8671231
171082815	171082838	2	-	27260156	PC3	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.3579048444488173	[145]	[88,139,145,85]	-7	hSpCas9	negative selection	8671232
171061131	171061154	2	+	27260156	PC3	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.08938198765518357	[590]	[339,573,1092,762]	2	hSpCas9	negative selection	8671233
171061135	171061158	2	-	27260156	PATU8988T	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	1.8390581216563362	[34]	[36,62,232,145]	9	hSpCas9	negative selection	8728229
171082829	171082852	2	+	27260156	PATU8988T	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.555786945354856	[264]	[194,462,245,631]	8	hSpCas9	negative selection	8728230
171061078	171061101	2	+	27260156	PATU8988T	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.4257786456503365	[1803]	[2277,2378,2196,2532]	7	hSpCas9	negative selection	8728231
171028377	171028400	2	-	27260156	PATU8988T	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.22858173988722696	[251]	[300,250,146,130]	-4	hSpCas9	negative selection	8792482
171082815	171082838	2	-	27260156	PATU8988T	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	0.23303156708215345	[145]	[271,232,86,70]	4	hSpCas9	negative selection	8792483
171061131	171061154	2	+	27260156	PATU8988T	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.1080623554804086	[590]	[533,798,533,612]	1	hSpCas9	negative selection	8792484
171061135	171061158	2	-	27260156	T47D	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.8246808692506238	[34]	[103,56,47,81]	9	hSpCas9	negative selection	8849480
171082829	171082852	2	+	27260156	T47D	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.3923283440024443	[264]	[360,472,355,425]	8	hSpCas9	negative selection	8849481
171061078	171061101	2	+	27260156	T47D	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.5564621505037199	[1803]	[3196,2689,3157,3359]	9	hSpCas9	negative selection	8849482
171028377	171028400	2	-	27260156	T47D	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.1913713290310588	[251]	[241,215,354,215]	-4	hSpCas9	negative selection	8913733
171082815	171082838	2	-	27260156	T47D	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.19018167502351724	[145]	[185,170,118,117]	-4	hSpCas9	negative selection	8913734
171061131	171061154	2	+	27260156	T47D	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.26069368496510537	[590]	[724,828,794,953]	5	hSpCas9	negative selection	8913735
171061135	171061158	2	-	27260156	SU8686	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.895550455881116	[34]	[29,33,31,188]	9	hSpCas9	negative selection	8970731
171082829	171082852	2	+	27260156	SU8686	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.40142270190389695	[264]	[299,342,277,491]	6	hSpCas9	negative selection	8970732
171061078	171061101	2	+	27260156	SU8686	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.5338876376542241	[1803]	[2309,2228,2939,3017]	8	hSpCas9	negative selection	8970733
171028377	171028400	2	-	27260156	SU8686	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.4574371189874036	[251]	[188,138,174,236]	-6	hSpCas9	negative selection	9034984
171082815	171082838	2	-	27260156	SU8686	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.15614398848748223	[145]	[103,90,139,203]	-3	hSpCas9	negative selection	9034985
171061131	171061154	2	+	27260156	SU8686	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.04694201570329498	[590]	[605,604,478,745]	0	hSpCas9	negative selection	9034986
171061135	171061158	2	-	27260156	SKES1	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.4690501298282679	[34]	[22,137,13,27]	8	hSpCas9	negative selection	9091982
171082829	171082852	2	+	27260156	SKES1	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	-0.00801202645421284	[264]	[341,309,194,223]	0	hSpCas9	negative selection	9091983
171061078	171061101	2	+	27260156	SKES1	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.5101266388549135	[1803]	[2894,2808,2238,2382]	8	hSpCas9	negative selection	9091984
171028377	171028400	2	-	27260156	SKES1	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.4151591695697563	[251]	[223,241,156,145]	-7	hSpCas9	negative selection	9156235
171082815	171082838	2	-	27260156	SKES1	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	0.002440541345174463	[145]	[245,134,103,113]	0	hSpCas9	negative selection	9156236
171061131	171061154	2	+	27260156	SKES1	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.2474429615005631	[590]	[914,662,723,534]	5	hSpCas9	negative selection	9156237
171061135	171061158	2	-	27260156	TOV112D	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.47675190227990427	[34]	[13,42,95,37]	8	hSpCas9	negative selection	9213233
171082829	171082852	2	+	27260156	TOV112D	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.6075744074113024	[264]	[328,520,337,449]	9	hSpCas9	negative selection	9213234
171061078	171061101	2	+	27260156	TOV112D	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.399204824385035	[1803]	[2468,3395,2342,1597]	7	hSpCas9	negative selection	9213235
171028377	171028400	2	-	27260156	TOV112D	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.6667062933838397	[251]	[155,311,150,56]	-8	hSpCas9	negative selection	9277486
171082815	171082838	2	-	27260156	TOV112D	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.21015795576729257	[145]	[110,132,144,116]	-4	hSpCas9	negative selection	9277487
171061131	171061154	2	+	27260156	TOV112D	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.2896300920895192	[590]	[654,948,738,602]	5	hSpCas9	negative selection	9277488
171061135	171061158	2	-	27260156	TC71	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.9730319080957917	[34]	[64,148,27,52]	9	hSpCas9	negative selection	9334484
171082829	171082852	2	+	27260156	TC71	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.37685095697759835	[264]	[349,388,286,457]	8	hSpCas9	negative selection	9334485
171061078	171061101	2	+	27260156	TC71	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.4637714189604534	[1803]	[2669,2848,2431,2727]	9	hSpCas9	negative selection	9334486
171028377	171028400	2	-	27260156	TC71	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.03655389224144978	[251]	[293,292,280,178]	-1	hSpCas9	negative selection	9398737
171082815	171082838	2	-	27260156	TC71	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.40552112705137255	[145]	[96,122,109,144]	-8	hSpCas9	negative selection	9398738
171061131	171061154	2	+	27260156	TC71	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.20673284357029775	[590]	[600,797,707,826]	5	hSpCas9	negative selection	9398739
171061135	171061158	2	-	27260156	TC32	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.1988638769094866	[34]	[25,27,24,33]	-4	hSpCas9	negative selection	9455735
171082829	171082852	2	+	27260156	TC32	viability	AGAGCTTTCGTTATTTGTTGAGG	TLK1	ENSG00000198586	0.6066614906493708	[264]	[284,328,346,568]	8	hSpCas9	negative selection	9455736
171061078	171061101	2	+	27260156	TC32	viability	TACCCTGACTACTTTCATTCTGG	TLK1	ENSG00000198586	0.49353785640094516	[1803]	[2204,1870,3067,2607]	8	hSpCas9	negative selection	9455737
171028377	171028400	2	-	27260156	TC32	viability	TTTGGCAGAATATCATGAACAGG	TLK1	ENSG00000198586	-0.10889050126200872	[251]	[147,233,245,245]	-2	hSpCas9	negative selection	9519988
171082815	171082838	2	-	27260156	TC32	viability	GAAAGCTCTAATCACAGTTTTGG	TLK1	ENSG00000198586	-0.36083588648141807	[145]	[100,113,62,133]	-6	hSpCas9	negative selection	9519989
171061131	171061154	2	+	27260156	TC32	viability	GATTCCGATTGTTTCTTCTCCGG	TLK1	ENSG00000198586	0.14293878244117914	[590]	[781,445,680,554]	2	hSpCas9	negative selection	9519990
171006160	171006183	2	-	27869803	HPAFII	viability after 27 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	0.284247390867987	[46]	[64,0,NaN]	2	hSpCas9	negative selection	9572282
171056550	171056573	2	-	27869803	HPAFII	viability after 27 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	1.3572469072375468	[445]	[939,317,NaN]	9	hSpCas9	negative selection	9572283
171160308	171160331	2	+	27869803	HPAFII	viability after 27 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	-1.2176038064558554	[112]	[12,35,NaN]	-7	hSpCas9	negative selection	9572284
171160315	171160338	2	+	27869803	HPAFII	viability after 27 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.39122046961331947	[397]	[134,179,NaN]	-3	hSpCas9	negative selection	9572285
171006160	171006183	2	-	27869803	HPAFII	viability after 15 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-0.11923988652330086	[46]	[101,11,NaN]	-1	hSpCas9	negative selection	9654731
171056550	171056573	2	-	27869803	HPAFII	viability after 15 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.5963054029269629	[445]	[1278,379,NaN]	6	hSpCas9	negative selection	9654732
171160308	171160331	2	+	27869803	HPAFII	viability after 15 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.44898090676711866	[112]	[314,72,NaN]	5	hSpCas9	negative selection	9654733
171160315	171160338	2	+	27869803	HPAFII	viability after 15 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.11268482482137354	[397]	[439,367,NaN]	-1	hSpCas9	negative selection	9654734
171006160	171006183	2	-	27869803	ASPC1	viability after 36 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-1.9331838569072026	[92]	[18,0,6]	-9	hSpCas9	negative selection	9737180
171056550	171056573	2	-	27869803	ASPC1	viability after 36 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.7400645607860826	[917]	[908,604,211]	7	hSpCas9	negative selection	9737181
171160308	171160331	2	+	27869803	ASPC1	viability after 36 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	-0.0742968242240582	[449]	[186,137,129]	-1	hSpCas9	negative selection	9737182
171160315	171160338	2	+	27869803	ASPC1	viability after 36 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	0.9954181292468984	[666]	[997,274,234]	8	hSpCas9	negative selection	9737183
171006160	171006183	2	-	27869803	PATU8988S	viability after 35 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-2.9040659714183095	[194]	[6,13,NaN]	-9	hSpCas9	negative selection	9819629
171056550	171056573	2	-	27869803	PATU8988S	viability after 35 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.15948686817075375	[914]	[451,370,NaN]	1	hSpCas9	negative selection	9819630
171160308	171160331	2	+	27869803	PATU8988S	viability after 35 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.9097994588213507	[349]	[193,335,NaN]	8	hSpCas9	negative selection	9819631
171160315	171160338	2	+	27869803	PATU8988S	viability after 35 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-1.412673664988366	[818]	[78,168,NaN]	-8	hSpCas9	negative selection	9819632
171006160	171006183	2	-	27869803	PATU8988S	viability after 31 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	-1.6346534327519098	[194]	[28,19,NaN]	-8	hSpCas9	negative selection	9902078
171056550	171056573	2	-	27869803	PATU8988S	viability after 31 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	0.16630723048314067	[914]	[353,479,NaN]	2	hSpCas9	negative selection	9902079
171160308	171160331	2	+	27869803	PATU8988S	viability after 31 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	0.6131108163209411	[349]	[139,306,NaN]	7	hSpCas9	negative selection	9902080
171160315	171160338	2	+	27869803	PATU8988S	viability after 31 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-1.0236514357695201	[818]	[113,219,NaN]	-7	hSpCas9	negative selection	9902081
171006160	171006183	2	-	27869803	HPAFII	viability after 35 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	1.0480165692175345	[46]	[91,0,NaN]	7	hSpCas9	negative selection	9984527
171056550	171056573	2	-	27869803	HPAFII	viability after 35 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	1.4583611745005163	[445]	[817,397,NaN]	8	hSpCas9	negative selection	9984528
171160308	171160331	2	+	27869803	HPAFII	viability after 35 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	-1.491287645892121	[112]	[9,31,NaN]	-7	hSpCas9	negative selection	9984529
171160315	171160338	2	+	27869803	HPAFII	viability after 35 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.3635519696215642	[397]	[70,252,NaN]	-2	hSpCas9	negative selection	9984530
171006160	171006183	2	-	27869803	HPAFII	viability after 31 days	AATGGATCTAACTTCCCAGGGGG	TLK1	ENSG00000198586	0.9892936212552113	[46]	[93,6,NaN]	7	hSpCas9	negative selection	10066976
171056550	171056573	2	-	27869803	HPAFII	viability after 31 days	ACTCAGTACCAGGGTGGAAATGG	TLK1	ENSG00000198586	1.1987061297176163	[445]	[764,366,NaN]	8	hSpCas9	negative selection	10066977
171160308	171160331	2	+	27869803	HPAFII	viability after 31 days	ATGGCGGCGTGTGATTCAGCAGG	TLK1	ENSG00000198586	-0.5974376240115067	[112]	[39,43,NaN]	-4	hSpCas9	negative selection	10066978
171160315	171160338	2	+	27869803	HPAFII	viability after 31 days	CGTGTGATTCAGCAGGGACCTGG	TLK1	ENSG00000198586	-0.02635045518142831	[397]	[192,247,NaN]	0	hSpCas9	negative selection	10066979
171006162	171006185	2	-	28162770	P31FUJ	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	-0.5624246910917419	[234]	[186]	-5	hSpCas9	negative selection	10251151
171061135	171061158	2	-	28162770	P31FUJ	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.449339365007306	[176]	[283]	5	hSpCas9	negative selection	10251152
171053784	171053807	2	-	28162770	P31FUJ	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-0.12719201645377984	[236]	[254]	-1	hSpCas9	negative selection	10251153
170996652	170996675	2	-	28162770	P31FUJ	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	0.7537772798233	[53]	[106]	8	hSpCas9	negative selection	10251154
171056556	171056579	2	-	28162770	P31FUJ	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.2417002351790664	[302]	[420]	2	hSpCas9	negative selection	10251155
171053761	171053784	2	-	28162770	P31FUJ	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	1.0283226114107837	[62]	[150]	9	hSpCas9	negative selection	10251156
171056460	171056483	2	+	28162770	P31FUJ	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	-0.14498432562296132	[238]	[253]	-1	hSpCas9	negative selection	10251157
171049892	171049915	2	-	28162770	P31FUJ	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	1.1214263823762938	[105]	[270]	9	hSpCas9	negative selection	10251158
171049875	171049898	2	+	28162770	P31FUJ	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	-0.13123729384969662	[520]	[558]	-1	hSpCas9	negative selection	10251159
171049846	171049869	2	-	28162770	P31FUJ	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.3614780577008212	[462]	[698]	4	hSpCas9	negative selection	10251160
171006162	171006185	2	-	28162770	TF1	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10420517
171061135	171061158	2	-	28162770	TF1	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	NaN	[NaN]	[216]	1	hSpCas9	negative selection	10420518
171053784	171053807	2	-	28162770	TF1	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10420519
170996652	170996675	2	-	28162770	TF1	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10420520
171056556	171056579	2	-	28162770	TF1	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10420521
171053761	171053784	2	-	28162770	TF1	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10420522
171056460	171056483	2	+	28162770	TF1	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	NaN	[NaN]	[446]	1	hSpCas9	negative selection	10420523
171049892	171049915	2	-	28162770	TF1	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10420524
171049875	171049898	2	+	28162770	TF1	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	NaN	[NaN]	[459]	1	hSpCas9	negative selection	10420525
171049846	171049869	2	-	28162770	TF1	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	NaN	[NaN]	[492]	1	hSpCas9	negative selection	10420526
171006162	171006185	2	-	28162770	SKM1	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	-0.23703919730084938	[65]	[98]	-2	hSpCas9	negative selection	10589883
171061135	171061158	2	-	28162770	SKM1	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.8725852938736488	[37]	[122]	8	hSpCas9	negative selection	10589884
171053784	171053807	2	-	28162770	SKM1	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-0.07949792031436943	[51]	[86]	0	hSpCas9	negative selection	10589885
170996652	170996675	2	-	28162770	SKM1	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	0.6925714748077527	[13]	[39]	6	hSpCas9	negative selection	10589886
171056556	171056579	2	-	28162770	SKM1	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.33669604799705266	[85]	[191]	3	hSpCas9	negative selection	10589887
171053761	171053784	2	-	28162770	SKM1	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	0.6109577092541005	[19]	[53]	6	hSpCas9	negative selection	10589888
171056460	171056483	2	+	28162770	SKM1	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	-0.36828373057910185	[91]	[125]	-3	hSpCas9	negative selection	10589889
171049892	171049915	2	-	28162770	SKM1	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	0.07981790803909089	[37]	[70]	0	hSpCas9	negative selection	10589890
171049875	171049898	2	+	28162770	SKM1	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	1.4085646547601427	[87]	[412]	9	hSpCas9	negative selection	10589891
171049846	171049869	2	-	28162770	SKM1	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	-0.02593258351091632	[109]	[190]	0	hSpCas9	negative selection	10589892
171006162	171006185	2	-	28162770	SKM1	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	-0.23703919730084938	[65]	[98]	-2	hSpCas9	negative selection	10759249
171061135	171061158	2	-	28162770	SKM1	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.8725852938736488	[37]	[122]	8	hSpCas9	negative selection	10759250
171053784	171053807	2	-	28162770	SKM1	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-0.07949792031436943	[51]	[86]	0	hSpCas9	negative selection	10759251
170996652	170996675	2	-	28162770	SKM1	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	0.6925714748077527	[13]	[39]	6	hSpCas9	negative selection	10759252
171056556	171056579	2	-	28162770	SKM1	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.33669604799705266	[85]	[191]	3	hSpCas9	negative selection	10759253
171053761	171053784	2	-	28162770	SKM1	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	0.6109577092541005	[19]	[53]	6	hSpCas9	negative selection	10759254
171056460	171056483	2	+	28162770	SKM1	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	-0.36828373057910185	[91]	[125]	-3	hSpCas9	negative selection	10759255
171049892	171049915	2	-	28162770	SKM1	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	0.07981790803909089	[37]	[70]	0	hSpCas9	negative selection	10759256
171049875	171049898	2	+	28162770	SKM1	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	1.4085646547601427	[87]	[412]	9	hSpCas9	negative selection	10759257
171049846	171049869	2	-	28162770	SKM1	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	-0.02593258351091632	[109]	[190]	0	hSpCas9	negative selection	10759258
171006162	171006185	2	-	28162770	PL21	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	-0.5766662442086771	[256]	[74]	-4	hSpCas9	negative selection	10928615
171061135	171061158	2	-	28162770	PL21	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	2.1601415465574014	[127]	[248]	9	hSpCas9	negative selection	10928616
171053784	171053807	2	-	28162770	PL21	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-0.00149424668033038	[114]	[49]	0	hSpCas9	negative selection	10928617
170996652	170996675	2	-	28162770	PL21	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	-0.500300103651772	[64]	[19]	-4	hSpCas9	negative selection	10928618
171056556	171056579	2	-	28162770	PL21	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.5688619208556235	[363]	[234]	5	hSpCas9	negative selection	10928619
171053761	171053784	2	-	28162770	PL21	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	-0.013985190863527341	[57]	[24]	0	hSpCas9	negative selection	10928620
171056460	171056483	2	+	28162770	PL21	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	0.3070548184058319	[246]	[132]	2	hSpCas9	negative selection	10928621
171049892	171049915	2	-	28162770	PL21	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	-1.323422341567693	[114]	[19]	-7	hSpCas9	negative selection	10928622
171049875	171049898	2	+	28162770	PL21	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	-0.07166500097220585	[296]	[122]	0	hSpCas9	negative selection	10928623
171049846	171049869	2	-	28162770	PL21	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	-0.22555636628824605	[316]	[117]	-2	hSpCas9	negative selection	10928624
171006162	171006185	2	-	28162770	P31FUJ	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	-0.5624246910917419	[234]	[186]	-5	hSpCas9	negative selection	11097981
171061135	171061158	2	-	28162770	P31FUJ	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.449339365007306	[176]	[283]	5	hSpCas9	negative selection	11097982
171053784	171053807	2	-	28162770	P31FUJ	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-0.12719201645377984	[236]	[254]	-1	hSpCas9	negative selection	11097983
170996652	170996675	2	-	28162770	P31FUJ	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	0.7537772798233	[53]	[106]	8	hSpCas9	negative selection	11097984
171056556	171056579	2	-	28162770	P31FUJ	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.2417002351790664	[302]	[420]	2	hSpCas9	negative selection	11097985
171053761	171053784	2	-	28162770	P31FUJ	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	1.0283226114107837	[62]	[150]	9	hSpCas9	negative selection	11097986
171056460	171056483	2	+	28162770	P31FUJ	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	-0.14498432562296132	[238]	[253]	-1	hSpCas9	negative selection	11097987
171049892	171049915	2	-	28162770	P31FUJ	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	1.1214263823762938	[105]	[270]	9	hSpCas9	negative selection	11097988
171049875	171049898	2	+	28162770	P31FUJ	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	-0.13123729384969662	[520]	[558]	-1	hSpCas9	negative selection	11097989
171049846	171049869	2	-	28162770	P31FUJ	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.3614780577008212	[462]	[698]	4	hSpCas9	negative selection	11097990
171006162	171006185	2	-	28162770	OCIAML5	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	0.11093922165380143	[157]	[307]	0	hSpCas9	negative selection	11267347
171061135	171061158	2	-	28162770	OCIAML5	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.46986152402336523	[127]	[319]	4	hSpCas9	negative selection	11267348
171053784	171053807	2	-	28162770	OCIAML5	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	0.6891745524278412	[66]	[194]	6	hSpCas9	negative selection	11267349
170996652	170996675	2	-	28162770	OCIAML5	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	-0.055599964949129	[37]	[65]	0	hSpCas9	negative selection	11267350
171056556	171056579	2	-	28162770	OCIAML5	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.797026267276875	[131]	[413]	7	hSpCas9	negative selection	11267351
171053761	171053784	2	-	28162770	OCIAML5	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	1.4698615240233655	[28]	[144]	9	hSpCas9	negative selection	11267352
171056460	171056483	2	+	28162770	OCIAML5	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	0.49188783035336425	[168]	[428]	4	hSpCas9	negative selection	11267353
171049892	171049915	2	-	28162770	OCIAML5	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	0.006757366175308754	[58]	[106]	0	hSpCas9	negative selection	11267354
171049875	171049898	2	+	28162770	OCIAML5	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	-0.12336859268139122	[244]	[405]	-1	hSpCas9	negative selection	11267355
171049846	171049869	2	-	28162770	OCIAML5	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.49495250498619603	[227]	[579]	4	hSpCas9	negative selection	11267356
171006162	171006185	2	-	28162770	EOL1	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	-0.022503348480506447	[427]	[221]	0	hSpCas9	negative selection	11436713
171061135	171061158	2	-	28162770	EOL1	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.506482579594123	[158]	[118]	4	hSpCas9	negative selection	11436714
171053784	171053807	2	-	28162770	EOL1	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-0.4336438673035995	[281]	[109]	-3	hSpCas9	negative selection	11436715
170996652	170996675	2	-	28162770	EOL1	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	-0.05079017419519616	[115]	[58]	0	hSpCas9	negative selection	11436716
171056556	171056579	2	-	28162770	EOL1	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	-0.09388947668614156	[629]	[310]	0	hSpCas9	negative selection	11436717
171053761	171053784	2	-	28162770	EOL1	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	-0.32481169736618276	[125]	[52]	-2	hSpCas9	negative selection	11436718
171056460	171056483	2	+	28162770	EOL1	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	0.47223589944863115	[378]	[276]	4	hSpCas9	negative selection	11436719
171049892	171049915	2	-	28162770	EOL1	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	0.28983223565227867	[117]	[75]	2	hSpCas9	negative selection	11436720
171049875	171049898	2	+	28162770	EOL1	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	0.8829000742120433	[491]	[477]	7	hSpCas9	negative selection	11436721
171049846	171049869	2	-	28162770	EOL1	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.2834421928118447	[392]	[251]	2	hSpCas9	negative selection	11436722
171006162	171006185	2	-	28162770	MOLM13	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	-0.8738019681642135	[440]	[173]	-5	hSpCas9	negative selection	11606079
171061135	171061158	2	-	28162770	MOLM13	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.35287272120465585	[260]	[240]	2	hSpCas9	negative selection	11606080
171053784	171053807	2	-	28162770	MOLM13	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	0.36994433113261954	[258]	[241]	2	hSpCas9	negative selection	11606081
170996652	170996675	2	-	28162770	MOLM13	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	-0.70614001823047	[87]	[38]	-4	hSpCas9	negative selection	11606082
171056556	171056579	2	-	28162770	MOLM13	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.766298117480258	[469]	[577]	6	hSpCas9	negative selection	11606083
171053761	171053784	2	-	28162770	MOLM13	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	0.5473238490389836	[52]	[55]	4	hSpCas9	negative selection	11606084
171056460	171056483	2	+	28162770	MOLM13	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	-0.012300797259515939	[384]	[275]	0	hSpCas9	negative selection	11606085
171049892	171049915	2	-	28162770	MOLM13	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	0.008457762907281507	[186]	[135]	0	hSpCas9	negative selection	11606086
171049875	171049898	2	+	28162770	MOLM13	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	-0.27217545128051385	[465]	[278]	-2	hSpCas9	negative selection	11606087
171049846	171049869	2	-	28162770	MOLM13	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.04012312276152863	[720]	[535]	0	hSpCas9	negative selection	11606088
171006162	171006185	2	-	28162770	HEL	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	0.05137856008105002	[338]	[224]	0	hSpCas9	negative selection	11775445
171061135	171061158	2	-	28162770	HEL	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.08956538479598625	[205]	[123]	0	hSpCas9	negative selection	11775446
171053784	171053807	2	-	28162770	HEL	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-0.7295942163242485	[232]	[89]	-5	hSpCas9	negative selection	11775447
170996652	170996675	2	-	28162770	HEL	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	0.11667002033276908	[71]	[49]	0	hSpCas9	negative selection	11775448
171056556	171056579	2	-	28162770	HEL	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	1.0015322206395814	[424]	[544]	8	hSpCas9	negative selection	11775449
171053761	171053784	2	-	28162770	HEL	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	0.008866730798254396	[89]	[57]	0	hSpCas9	negative selection	11775450
171056460	171056483	2	+	28162770	HEL	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	0.9515460051542779	[242]	[300]	8	hSpCas9	negative selection	11775451
171049892	171049915	2	-	28162770	HEL	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	-0.51953259689852	[187]	[83]	-4	hSpCas9	negative selection	11775452
171049875	171049898	2	+	28162770	HEL	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	0.28181660549713083	[374]	[291]	2	hSpCas9	negative selection	11775453
171049846	171049869	2	-	28162770	HEL	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.09061958796621772	[455]	[310]	0	hSpCas9	negative selection	11775454
171006162	171006185	2	-	28162770	MV411	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	1.1067386878730336	[225]	[409]	8	hSpCas9	negative selection	11944811
171061135	171061158	2	-	28162770	MV411	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	1.0086506911956588	[117]	[199]	8	hSpCas9	negative selection	11944812
171053784	171053807	2	-	28162770	MV411	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-1.0099502919098766	[152]	[63]	-6	hSpCas9	negative selection	11944813
170996652	170996675	2	-	28162770	MV411	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	0.6928486991051379	[46]	[63]	6	hSpCas9	negative selection	11944814
171056556	171056579	2	-	28162770	MV411	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	-0.0552610726245345	[353]	[286]	0	hSpCas9	negative selection	11944815
171053761	171053784	2	-	28162770	MV411	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	0.49070870179513904	[48]	[57]	4	hSpCas9	negative selection	11944816
171056460	171056483	2	+	28162770	MV411	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	0.7964207543983649	[202]	[296]	7	hSpCas9	negative selection	11944817
171049892	171049915	2	-	28162770	MV411	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	0.5772853089663759	[108]	[136]	5	hSpCas9	negative selection	11944818
171049875	171049898	2	+	28162770	MV411	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	0.6189734114250325	[302]	[391]	5	hSpCas9	negative selection	11944819
171049846	171049869	2	-	28162770	MV411	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.690897370540703	[288]	[392]	6	hSpCas9	negative selection	11944820
171006162	171006185	2	-	28162770	MONOMAC1	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	-0.471211810498548	[155]	[128]	-4	hSpCas9	negative selection	12114177
171061135	171061158	2	-	28162770	MONOMAC1	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	1.1655332323251546	[69]	[179]	8	hSpCas9	negative selection	12114178
171053784	171053807	2	-	28162770	MONOMAC1	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-0.15439250965105983	[99]	[102]	-1	hSpCas9	negative selection	12114179
170996652	170996675	2	-	28162770	MONOMAC1	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	3.9200714559393104	[33]	[589]	9	hSpCas9	negative selection	12114180
171056556	171056579	2	-	28162770	MONOMAC1	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.46728344527488674	[223]	[354]	4	hSpCas9	negative selection	12114181
171053761	171053784	2	-	28162770	MONOMAC1	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	-1.5189649419469158	[44]	[17]	-8	hSpCas9	negative selection	12114182
171056460	171056483	2	+	28162770	MONOMAC1	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	0.4436350862478902	[126]	[197]	4	hSpCas9	negative selection	12114183
171049892	171049915	2	-	28162770	MONOMAC1	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	0.10104450587344094	[60]	[74]	1	hSpCas9	negative selection	12114184
171049875	171049898	2	+	28162770	MONOMAC1	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	-0.3075952222072521	[243]	[225]	-3	hSpCas9	negative selection	12114185
171049846	171049869	2	-	28162770	MONOMAC1	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.657589341882018	[192]	[348]	6	hSpCas9	negative selection	12114186
171006162	171006185	2	-	28162770	OCIAML2	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	0.114332675478995	[43]	[263]	1	hSpCas9	negative selection	12283543
171061135	171061158	2	-	28162770	OCIAML2	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	0.7052200101572564	[26]	[243]	7	hSpCas9	negative selection	12283544
171053784	171053807	2	-	28162770	OCIAML2	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	-0.025844982569265484	[26]	[146]	0	hSpCas9	negative selection	12283545
170996652	170996675	2	-	28162770	OCIAML2	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	0.8901175185357294	[10]	[112]	8	hSpCas9	negative selection	12283546
171056556	171056579	2	-	28162770	OCIAML2	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	0.5041818426670056	[64]	[510]	5	hSpCas9	negative selection	12283547
171053761	171053784	2	-	28162770	OCIAML2	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	1.4362607703663577	[14]	[224]	9	hSpCas9	negative selection	12283548
171056460	171056483	2	+	28162770	OCIAML2	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	1.1489788182858862	[23]	[294]	9	hSpCas9	negative selection	12283549
171049892	171049915	2	-	28162770	OCIAML2	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	-1.3007048237998489	[19]	[44]	-7	hSpCas9	negative selection	12283550
171049875	171049898	2	+	28162770	OCIAML2	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	1.0803853435556574	[42]	[503]	8	hSpCas9	negative selection	12283551
171049846	171049869	2	-	28162770	OCIAML2	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.723141918154519	[59]	[548]	7	hSpCas9	negative selection	12283552
171006162	171006185	2	-	28162770	OCIAML3	viability	GGAATGGATCTAACTTCCCAGGG	TLK1	ENSG00000198586	-1.1148398036256038	[65]	[91]	-7	hSpCas9	negative selection	12452909
171061135	171061158	2	-	28162770	OCIAML3	viability	GACACCGGAGAAGAAACAATCGG	TLK1	ENSG00000198586	-0.26385903863183213	[34]	[87]	-2	hSpCas9	negative selection	12452910
171053784	171053807	2	-	28162770	OCIAML3	viability	CCAGGACCTGGAAAAGAAGGAGG	TLK1	ENSG00000198586	0.2455276874825908	[37]	[135]	2	hSpCas9	negative selection	12452911
170996652	170996675	2	-	28162770	OCIAML3	viability	GGTTGTAAGCAGTGAAGCCAAGG	TLK1	ENSG00000198586	-1.535113951270595	[23]	[24]	-8	hSpCas9	negative selection	12452912
171056556	171056579	2	-	28162770	OCIAML3	viability	TCTTTTACTCAGTACCAGGGTGG	TLK1	ENSG00000198586	-0.15991180522963477	[93]	[253]	-1	hSpCas9	negative selection	12452913
171053761	171053784	2	-	28162770	OCIAML3	viability	GACGTATAGATGATTTGCTCAGG	TLK1	ENSG00000198586	0.1918675543229894	[28]	[99]	1	hSpCas9	negative selection	12452914
171056460	171056483	2	+	28162770	OCIAML3	viability	AGATGACTTACAGATGAGGAAGG	TLK1	ENSG00000198586	0.1702785598415551	[67]	[230]	1	hSpCas9	negative selection	12452915
171049892	171049915	2	-	28162770	OCIAML3	viability	ATGCAAGATCGATTACGCCTCGG	TLK1	ENSG00000198586	-0.9541832045684887	[42]	[66]	-6	hSpCas9	negative selection	12452916
171049875	171049898	2	+	28162770	OCIAML3	viability	TAACTGTTGTAAAGTGCCCGAGG	TLK1	ENSG00000198586	0.42063913564023825	[97]	[395]	4	hSpCas9	negative selection	12452917
171049846	171049869	2	-	28162770	OCIAML3	viability	GCGCTTCATTTACTGAACAATGG	TLK1	ENSG00000198586	0.5377822322313779	[114]	[503]	5	hSpCas9	negative selection	12452918