Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:11011
• Symbol:TLK2
• Description:tousled like kinase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/TLK2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
62565083	62565106	17	+	26472758	Jiyoye	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.39316852351199394	[413]	[409]	3	hSpCas9	negative selection	166084
62600716	62600739	17	+	26472758	Jiyoye	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	-1.490945004474913	[81]	[21]	-7	hSpCas9	negative selection	166085
62573205	62573228	17	+	26472758	Jiyoye	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	3.003542645499279	[20]	[126]	9	hSpCas9	negative selection	166086
62578497	62578520	17	+	26472758	Jiyoye	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	1.9217485543356314	[27]	[79]	8	hSpCas9	negative selection	166087
62606220	62606243	17	+	26472758	Jiyoye	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.3796946450837664	[264]	[259]	3	hSpCas9	negative selection	166088
62578473	62578496	17	+	26472758	Jiyoye	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	0.2046414298167143	[480]	[417]	1	hSpCas9	negative selection	166089
62602053	62602076	17	+	26472758	Jiyoye	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	-0.7604245669901951	[309]	[137]	-5	hSpCas9	negative selection	166090
62608119	62608142	17	-	26472758	Jiyoye	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	-0.3249530076563356	[396]	[238]	-2	hSpCas9	negative selection	166091
62612473	62612496	17	-	26472758	Jiyoye	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-0.7761318318571864	[703]	[309]	-5	hSpCas9	negative selection	166092
62573330	62573353	17	+	26472758	Jiyoye	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-0.402853674850056	[134]	[76]	-3	hSpCas9	negative selection	166093
62565083	62565106	17	+	26472758	KBM7	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	-0.190200103466728	[1288,882]	[503,384]	-2	hSpCas9	negative selection	357202
62600716	62600739	17	+	26472758	KBM7	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	0.4357068967347498	[187,221]	[129,133]	5	hSpCas9	negative selection	357203
62573205	62573228	17	+	26472758	KBM7	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	-0.18367886686338641	[674,688]	[434,148]	-2	hSpCas9	negative selection	357204
62578497	62578520	17	+	26472758	KBM7	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	0.461374336710586	[211,277]	[216,111]	5	hSpCas9	negative selection	357205
62606220	62606243	17	+	26472758	KBM7	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.774528939552362	[1266,927]	[946,806]	8	hSpCas9	negative selection	357206
62578473	62578496	17	+	26472758	KBM7	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-0.21555810222640548	[1742,1379]	[639,616]	-2	hSpCas9	negative selection	357207
62602053	62602076	17	+	26472758	KBM7	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	-0.09327561832749598	[685,647]	[302,286]	-1	hSpCas9	negative selection	357208
62608119	62608142	17	-	26472758	KBM7	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	0.030948371070066427	[1799,1522]	[771,815]	0	hSpCas9	negative selection	357209
62612473	62612496	17	-	26472758	KBM7	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-0.23512586931408208	[2580,2162]	[1063,835]	-2	hSpCas9	negative selection	357210
62573330	62573353	17	+	26472758	KBM7	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	0.11018071898833892	[638,648]	[211,432]	1	hSpCas9	negative selection	357211
62565083	62565106	17	+	26472758	Raji	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.3504264660199272	[435]	[128]	3	hSpCas9	negative selection	548320
62600716	62600739	17	+	26472758	Raji	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	-0.780141735367988	[110]	[14]	-5	hSpCas9	negative selection	548321
62573205	62573228	17	+	26472758	Raji	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.4759466048529426	[346]	[111]	4	hSpCas9	negative selection	548322
62578497	62578520	17	+	26472758	Raji	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	0.8322036996777163	[166]	[68]	7	hSpCas9	negative selection	548323
62606220	62606243	17	+	26472758	Raji	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.6887257204160586	[531]	[198]	6	hSpCas9	negative selection	548324
62578473	62578496	17	+	26472758	Raji	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-0.42229652984636723	[767]	[132]	-3	hSpCas9	negative selection	548325
62602053	62602076	17	+	26472758	Raji	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	-0.08153418141176016	[496]	[108]	0	hSpCas9	negative selection	548326
62608119	62608142	17	-	26472758	Raji	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	-0.16184480287045155	[886]	[183]	-1	hSpCas9	negative selection	548327
62612473	62612496	17	-	26472758	Raji	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-0.48794568090581625	[1256]	[207]	-4	hSpCas9	negative selection	548328
62573330	62573353	17	+	26472758	Raji	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-1.0126162407370305	[425]	[48]	-6	hSpCas9	negative selection	548329
62565083	62565106	17	+	26472758	K562	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	-0.5806201139537843	[984]	[555]	-4	hSpCas9	negative selection	739438
62600716	62600739	17	+	26472758	K562	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	-0.7000861597418495	[101]	[52]	-4	hSpCas9	negative selection	739439
62573205	62573228	17	+	26472758	K562	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	-0.8825724777705299	[628]	[287]	-5	hSpCas9	negative selection	739440
62578497	62578520	17	+	26472758	K562	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-0.5707415968799576	[277]	[157]	-4	hSpCas9	negative selection	739441
62606220	62606243	17	+	26472758	K562	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.09435343846288946	[991]	[893]	0	hSpCas9	negative selection	739442
62578473	62578496	17	+	26472758	K562	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-1.1160680372177723	[1383]	[538]	-6	hSpCas9	negative selection	739443
62602053	62602076	17	+	26472758	K562	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	-0.979662043822771	[569]	[243]	-5	hSpCas9	negative selection	739444
62608119	62608142	17	-	26472758	K562	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	0.49454065679661907	[1140]	[1356]	4	hSpCas9	negative selection	739445
62612473	62612496	17	-	26472758	K562	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-0.6151784131077211	[1897]	[1045]	-4	hSpCas9	negative selection	739446
62573330	62573353	17	+	26472758	K562	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-0.9322464200128724	[589]	[260]	-5	hSpCas9	negative selection	739447
62520823	62520846	17	+	24336569	HL60	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	0.7583858940243314	[808]	[2895]	6	hSpCas9	negative selection	2300662
62565075	62565098	17	-	24336569	HL60	viability	CAGTAAATGAGGCTCCGTGTCGG	TLK2	ENSG00000146872	0.7502046360220532	[310]	[1106]	6	hSpCas9	negative selection	2300663
62565083	62565106	17	+	24336569	HL60	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.673710957103659	[928]	[3135]	6	hSpCas9	negative selection	2300664
62573205	62573228	17	+	24336569	HL60	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.8157763249459028	[919]	[3426]	6	hSpCas9	negative selection	2300665
62578473	62578496	17	+	24336569	HL60	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-0.8781314642467689	[1512]	[1741]	-7	hSpCas9	negative selection	2300666
62578496	62578519	17	+	24336569	HL60	viability	CAGAGCTGGAGAGACTAGAAAGG	TLK2	ENSG00000146872	1.6040111783475677	[163]	[1054]	9	hSpCas9	negative selection	2300667
62596575	62596598	17	+	24336569	HL60	viability	TTGTTTACAGGCATGCATGTAGG	TLK2	ENSG00000146872	1.2590178887554335	[957]	[4851]	8	hSpCas9	negative selection	2300668
62600702	62600725	17	+	24336569	HL60	viability	GAAACAGCACAAATTAATGTCGG	TLK2	ENSG00000146872	0.2852147004633543	[1421]	[3666]	2	hSpCas9	negative selection	2300669
62600711	62600734	17	+	24336569	HL60	viability	CAAATTAATGTCGGAGAAAGAGG	TLK2	ENSG00000146872	0.4008046916264326	[489]	[1368]	3	hSpCas9	negative selection	2300670
62600810	62600833	17	-	24336569	HL60	viability	AGTTAGACATACCTGGTTTGAGG	TLK2	ENSG00000146872	-0.26026725341766166	[325]	[575]	-2	hSpCas9	negative selection	2300671
62520823	62520846	17	+	24336569	KBM7	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.0664510320367605	[677]	[1765]	0	hSpCas9	negative selection	2367839
62565075	62565098	17	-	24336569	KBM7	viability	CAGTAAATGAGGCTCCGTGTCGG	TLK2	ENSG00000146872	-0.8990401040775999	[360]	[527]	-6	hSpCas9	negative selection	2367840
62565083	62565106	17	+	24336569	KBM7	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.012267407001642416	[1263]	[3476]	0	hSpCas9	negative selection	2367841
62573205	62573228	17	+	24336569	KBM7	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	-0.048877925444770765	[654]	[1726]	0	hSpCas9	negative selection	2367842
62578473	62578496	17	+	24336569	KBM7	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-0.8953917319193464	[741]	[1087]	-6	hSpCas9	negative selection	2367843
62578496	62578519	17	+	24336569	KBM7	viability	CAGAGCTGGAGAGACTAGAAAGG	TLK2	ENSG00000146872	0.5883105905744067	[396]	[1627]	5	hSpCas9	negative selection	2367844
62596575	62596598	17	+	24336569	KBM7	viability	TTGTTTACAGGCATGCATGTAGG	TLK2	ENSG00000146872	0.5630398344711138	[845]	[3408]	5	hSpCas9	negative selection	2367845
62600702	62600725	17	+	24336569	KBM7	viability	GAAACAGCACAAATTAATGTCGG	TLK2	ENSG00000146872	0.31604722276218644	[889]	[3021]	3	hSpCas9	negative selection	2367846
62600711	62600734	17	+	24336569	KBM7	viability	CAAATTAATGTCGGAGAAAGAGG	TLK2	ENSG00000146872	0.7485816832143859	[332]	[1525]	6	hSpCas9	negative selection	2367847
62600810	62600833	17	-	24336569	KBM7	viability	AGTTAGACATACCTGGTTTGAGG	TLK2	ENSG00000146872	0.8800325368420625	[303]	[1525]	7	hSpCas9	negative selection	2367848
62523503	62523526	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAGCCTCGACTTCTCAG	TLK2	ENSG00000146872	-0.3334344553746127	[914,176]	[125,59]	-1	dCas9-VP64	positive selection	2383753
62474531	62474554	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCAAGTAGCCGGGACTACAGG	TLK2	ENSG00000146872	-1.3915641432783492	[75,90]	[10,1]	-7	dCas9-VP64	positive selection	2383964
62466720	62466743	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCGGAGGTTGCAGTGAGCTAG	TLK2	ENSG00000146872	-1.3881494200540772	[95,289]	[14,16]	-7	dCas9-VP64	positive selection	2387255
62476255	62476278	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCTACCGCACCCAG	TLK2	ENSG00000146872	-0.46798260111423184	[1242,12]	[184,3]	-2	dCas9-VP64	positive selection	2387772
62469982	62470005	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCTTGAACCTGGGAGGTGGGAG	TLK2	ENSG00000146872	-1.7942305092270365	[61,1]	[0,1]	-8	dCas9-VP64	positive selection	2412446
62463513	62463536	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCACTGCACTCCAGCCAGG	TLK2	ENSG00000146872	0.6031003623548207	[86,54]	[14,31]	2	dCas9-VP64	positive selection	2416276
62476999	62477022	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAACTGCTTGAACCCGGGTGG	TLK2	ENSG00000146872	-0.49490286023555685	[54,83]	[3,16]	-2	dCas9-VP64	positive selection	2421114
62517467	62517490	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCCACCTTCCGG	TLK2	ENSG00000146872	-0.9430062856730932	[147,123]	[18,10]	-5	dCas9-VP64	positive selection	2422317
62478843	62478866	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACCGATCCGGATTAAGGGGCCGG	TLK2	ENSG00000146872	-0.12700872921917727	[27,47]	[3,10]	0	dCas9-VP64	positive selection	2423448
62478866	62478889	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCGGGTCCTGGGCACCAGCGG	TLK2	ENSG00000146872	-0.12139641850090932	[24,1]	[3,0]	0	dCas9-VP64	positive selection	2423450
62478912	62478935	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTGGGGGCCACTCGGGTGCGG	TLK2	ENSG00000146872	-1.1298963813595722	[23,52]	[3,2]	-6	dCas9-VP64	positive selection	2423451
62480833	62480856	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATTATATGAAGGGTTTGAGGGG	TLK2	ENSG00000146872	-0.594166674505666	[406,230]	[42,48]	-3	dCas9-VP64	positive selection	2423475
62480881	62480904	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGAACTAGGGAAGAAAAAGTGG	TLK2	ENSG00000146872	2.9132377154123774	[22,91]	[58,137]	8	dCas9-VP64	positive selection	2423476
62480812	62480835	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCTGTAAAAGTTGAGCACAGG	TLK2	ENSG00000146872	2.5191577558018903	[24,37]	[2,79]	8	dCas9-VP64	positive selection	2423477
62466663	62466686	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTAGCTGGGATTACAGGCAG	TLK2	ENSG00000146872	-1.0771701610192164	[3,202]	[1,19]	-6	dCas9-VP64	positive selection	2427109
62560702	62560725	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGCATGATCTCAG	TLK2	ENSG00000146872	2.493462356292235	[8,24]	[27,14]	8	dCas9-VP64	positive selection	2433612
62476538	62476561	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCCACTGCACTTCAGCCCGGG	TLK2	ENSG00000146872	4.131491632928274	[82,113]	[564,186]	9	dCas9-VP64	positive selection	2436963
62564275	62564298	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCTCAGCACTTTGG	TLK2	ENSG00000146872	-0.6796005969874881	[92,259]	[10,38]	-3	dCas9-VP64	positive selection	2447690
62583293	62583316	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACTAGCCTGGCCAACACAG	TLK2	ENSG00000146872	0.3601150748164519	[269,268]	[95,53]	1	dCas9-VP64	positive selection	2458905
62523503	62523526	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAGCCTCGACTTCTCAG	TLK2	ENSG00000146872	-0.34054073104189286	[370,392]	[107,88]	-3	dCas9-VP64	positive selection	2479008
62474531	62474554	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCAAGTAGCCGGGACTACAGG	TLK2	ENSG00000146872	0.7267888491255965	[43,18]	[15,16]	5	dCas9-VP64	positive selection	2479219
62466720	62466743	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCGGAGGTTGCAGTGAGCTAG	TLK2	ENSG00000146872	-0.15452703381003985	[117,34]	[33,11]	-1	dCas9-VP64	positive selection	2482510
62476255	62476278	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCTACCGCACCCAG	TLK2	ENSG00000146872	0.19591410252065838	[56,235]	[12,91]	1	dCas9-VP64	positive selection	2483027
62469982	62470005	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCTTGAACCTGGGAGGTGGGAG	TLK2	ENSG00000146872	1.9777309334960365	[57,27]	[33,74]	8	dCas9-VP64	positive selection	2507701
62463513	62463536	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCACTGCACTCCAGCCAGG	TLK2	ENSG00000146872	-0.5652196159145948	[243,309]	[59,60]	-5	dCas9-VP64	positive selection	2511531
62476999	62477022	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAACTGCTTGAACCCGGGTGG	TLK2	ENSG00000146872	0.07163893759037979	[96,162]	[32,54]	0	dCas9-VP64	positive selection	2516369
62517467	62517490	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCCACCTTCCGG	TLK2	ENSG00000146872	1.0287528959230179	[63,82]	[22,72]	6	dCas9-VP64	positive selection	2517572
62478843	62478866	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACCGATCCGGATTAAGGGGCCGG	TLK2	ENSG00000146872	-1.3717410757956139	[45,270]	[11,25]	-9	dCas9-VP64	positive selection	2518703
62478866	62478889	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCGGGTCCTGGGCACCAGCGG	TLK2	ENSG00000146872	-0.24548705446174113	[120,63]	[29,20]	-2	dCas9-VP64	positive selection	2518705
62478912	62478935	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTGGGGGCCACTCGGGTGCGG	TLK2	ENSG00000146872	-0.7197763491997522	[255,96]	[24,43]	-7	dCas9-VP64	positive selection	2518706
62480833	62480856	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATTATATGAAGGGTTTGAGGGG	TLK2	ENSG00000146872	-0.4654340114932831	[417,396]	[114,77]	-5	dCas9-VP64	positive selection	2518730
62480881	62480904	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGAACTAGGGAAGAAAAAGTGG	TLK2	ENSG00000146872	1.31640298020406	[141,178]	[65,190]	7	dCas9-VP64	positive selection	2518731
62480812	62480835	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCTGTAAAAGTTGAGCACAGG	TLK2	ENSG00000146872	0.19644064446201348	[19,9]	[4,5]	1	dCas9-VP64	positive selection	2518732
62466663	62466686	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTAGCTGGGATTACAGGCAG	TLK2	ENSG00000146872	0.14665344663969582	[27,75]	[10,24]	1	dCas9-VP64	positive selection	2522364
62560702	62560725	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGCATGATCTCAG	TLK2	ENSG00000146872	-0.3977265325465724	[58,186]	[26,32]	-4	dCas9-VP64	positive selection	2528867
62476538	62476561	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCCACTGCACTTCAGCCCGGG	TLK2	ENSG00000146872	-0.4132335770015192	[33,105]	[16,15]	-4	dCas9-VP64	positive selection	2532218
62564275	62564298	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCTCAGCACTTTGG	TLK2	ENSG00000146872	0.2134968510682193	[79,136]	[55,26]	1	dCas9-VP64	positive selection	2542945
62583293	62583316	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACTAGCCTGGCCAACACAG	TLK2	ENSG00000146872	-0.8374586120276372	[108,300]	[27,44]	-7	dCas9-VP64	positive selection	2554160
62481128	62481151	17	+	27013184	SW480	treatment with recombinant TRAIL	GATGGAAGAATTGCATAGCCTGG	TLK2	ENSG00000146872	-2.9137219974719475	[84,69]	[1,7]	-8	hSpCas9	positive selection	2961650
62481139	62481162	17	+	27013184	SW480	treatment with recombinant TRAIL	TGCATAGCCTGGACCCACGACGG	TLK2	ENSG00000146872	0.33211577548620513	[157,256]	[92,134]	1	hSpCas9	positive selection	2961652
62520797	62520820	17	+	27013184	SW480	treatment with recombinant TRAIL	AACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	1.580919821397601	[126,254]	[237,240]	7	hSpCas9	positive selection	2961655
62552307	62552330	17	+	27013184	SW480	treatment with recombinant TRAIL	GCAAAACAGTCCCTCATCTACGG	TLK2	ENSG00000146872	-1.1762581670768701	[201,255]	[53,27]	-5	hSpCas9	positive selection	2961658
62481152	62481175	17	+	27013184	SW480	treatment with recombinant TRAIL	CCCACGACGGCAGGAATTATTGG	TLK2	ENSG00000146872	1.884880329306585	[107,51]	[5,309]	8	hSpCas9	positive selection	2961662
62522252	62522275	17	+	27013184	SW480	treatment with recombinant TRAIL	GAACCATATGAAACTAGCCAAGG	TLK2	ENSG00000146872	0.1939680060893576	[32,72]	[28,19]	1	hSpCas9	positive selection	2961664
62552308	62552331	17	+	27013184	SW480	treatment with recombinant TRAIL	CAAAACAGTCCCTCATCTACGGG	TLK2	ENSG00000146872	-0.5538524933625278	[236,325]	[55,117]	-2	hSpCas9	positive selection	2961665
62552290	62552313	17	-	27013184	SW480	treatment with recombinant TRAIL	TTTTGCTGAGCCTACAATAAAGG	TLK2	ENSG00000146872	-4.239861639589716	[65,152]	[1,2]	-9	hSpCas9	positive selection	2961668
62552317	62552340	17	-	27013184	SW480	treatment with recombinant TRAIL	TTGCCAGATCCCGTAGATGAGGG	TLK2	ENSG00000146872	-1.9768185916206331	[278,326]	[39,22]	-7	hSpCas9	positive selection	2961671
62520795	62520818	17	-	27013184	SW480	treatment with recombinant TRAIL	GACGCTGCACAAGCTCTGGTTGG	TLK2	ENSG00000146872	-1.5762400536650056	[114,85]	[3,29]	-6	hSpCas9	positive selection	2961674
62552318	62552341	17	-	27013184	SW480	treatment with recombinant TRAIL	GTTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	1.4730349520503645	[103,72]	[124,82]	6	hSpCas9	positive selection	2961677
62520799	62520822	17	-	27013184	SW480	treatment with recombinant TRAIL	ATCCGACGCTGCACAAGCTCTGG	TLK2	ENSG00000146872	-1.6839601983414374	[19,55]	[1,8]	-6	hSpCas9	positive selection	2961679
62552393	62552416	17	-	27013184	SW480	treatment with recombinant TRAIL	TATCGATCACCAACCTACCTGGG	TLK2	ENSG00000146872	-2.3608335230752977	[160,133]	[2,25]	-8	hSpCas9	positive selection	2961681
62522255	62522278	17	-	27013184	SW480	treatment with recombinant TRAIL	CTACCTTGGCTAGTTTCATATGG	TLK2	ENSG00000146872	0.6973638858177696	[118,378]	[173,154]	3	hSpCas9	positive selection	2961683
62552394	62552417	17	-	27013184	SW480	treatment with recombinant TRAIL	TTATCGATCACCAACCTACCTGG	TLK2	ENSG00000146872	0.1622229556209649	[408,304]	[108,267]	0	hSpCas9	positive selection	2961685
62522269	62522292	17	-	27013184	SW480	treatment with recombinant TRAIL	ATACGAAATTATTACTACCTTGG	TLK2	ENSG00000146872	-1.2299835339423881	[81,101]	[17,14]	-5	hSpCas9	positive selection	2961686
62481155	62481178	17	+	27013184	SW480	treatment with recombinant TRAIL	ACGACGGCAGGAATTATTGGAGG	TLK2	ENSG00000146872	2.0134214368372643	[186,261]	[341,446]	8	hSpCas9	positive selection	2961688
62552314	62552337	17	+	27013184	SW480	treatment with recombinant TRAIL	AGTCCCTCATCTACGGGATCTGG	TLK2	ENSG00000146872	0.9522076419586334	[127,182]	[114,145]	4	hSpCas9	positive selection	2961692
62612491	62612514	17	+	27013184	SW480	treatment with recombinant TRAIL	GTCTCTACAAGTAGCCCTGCTGG	TLK2	ENSG00000146872	-0.7906259238038387	[123,199]	[20,65]	-4	hSpCas9	positive selection	2961693
62612515	62612538	17	+	27013184	SW480	treatment with recombinant TRAIL	GCTGCTATTGCATCAACCTCTGG	TLK2	ENSG00000146872	0.2416369292402647	[530,927]	[193,603]	1	hSpCas9	positive selection	2961695
62612516	62612539	17	+	27013184	SW480	treatment with recombinant TRAIL	CTGCTATTGCATCAACCTCTGGG	TLK2	ENSG00000146872	-0.5222180676494719	[504,628]	[164,173]	-2	hSpCas9	positive selection	2961696
62612517	62612540	17	+	27013184	SW480	treatment with recombinant TRAIL	TGCTATTGCATCAACCTCTGGGG	TLK2	ENSG00000146872	0.28707420485872515	[39,49]	[27,16]	1	hSpCas9	positive selection	2961699
62552384	62552407	17	+	27013184	SW480	treatment with recombinant TRAIL	ACAGACAGACCCAGGTAGGTTGG	TLK2	ENSG00000146872	0.3234408447879755	[190,223]	[128,85]	1	hSpCas9	positive selection	2961701
62612557	62612580	17	+	27013184	SW480	treatment with recombinant TRAIL	TCTAATTGAGACTGACTCCAAGG	TLK2	ENSG00000146872	0.9637062514684749	[186,71]	[116,107]	4	hSpCas9	positive selection	2961702
62481168	62481191	17	+	27013184	SW480	treatment with recombinant TRAIL	TTATTGGAGGCCAGGTTTACTGG	TLK2	ENSG00000146872	3.641492533511566	[67,47]	[286,359]	9	hSpCas9	positive selection	2961705
62481174	62481197	17	+	27013184	SW480	treatment with recombinant TRAIL	GAGGCCAGGTTTACTGGAGTAGG	TLK2	ENSG00000146872	0.017304842042697666	[191,184]	[60,112]	0	hSpCas9	positive selection	2961709
62481152	62481175	17	-	27013184	SW480	treatment with recombinant TRAIL	CCAATAATTCCTGCCGTCGTGGG	TLK2	ENSG00000146872	-1.200428832624842	[591,685]	[157,63]	-5	hSpCas9	positive selection	2961710
62612531	62612554	17	-	27013184	SW480	treatment with recombinant TRAIL	ACTGTTATTGGACGCCCCAGAGG	TLK2	ENSG00000146872	0.7563526014219167	[213,221]	[156,160]	3	hSpCas9	positive selection	2961712
62481153	62481176	17	-	27013184	SW480	treatment with recombinant TRAIL	TCCAATAATTCCTGCCGTCGTGG	TLK2	ENSG00000146872	-1.0249821878312768	[163,186]	[36,36]	-4	hSpCas9	positive selection	2961715
62481178	62481201	17	-	27013184	SW480	treatment with recombinant TRAIL	AACACCTACTCCAGTAAACCTGG	TLK2	ENSG00000146872	-5.5187659052968	[119,322]	[1,1]	-9	hSpCas9	positive selection	2961717
62536275	62536298	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCTGCTCTGTGTCAAGCCGAGG	TLK2	ENSG00000146872	-0.3356227351942814	[2,2]	[2,0]	-5	hSpCas9	positive selection	3026986
62536185	62536208	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGCCATCTAAACCATAGAGGGG	TLK2	ENSG00000146872	0.2678848491986041	[3,3]	[3,3]	6	hSpCas9	positive selection	3026987
62573242	62573265	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGAAGAGATAGAAAGACAACGG	TLK2	ENSG00000146872	-1.007568117216236	[3,3]	[1,0]	-9	hSpCas9	positive selection	3026988
62553712	62553735	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGACTTAGAGAAGAAGGAGGG	TLK2	ENSG00000146872	-0.05401344141480274	[4,4]	[4,2]	0	hSpCas9	positive selection	3026989
62536275	62536298	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCTGCTCTGTGTCAAGCCGAGG	TLK2	ENSG00000146872	-0.5531488076194718	[2,2]	[0,0]	-7	hSpCas9	positive selection	3094844
62536185	62536208	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGCCATCTAAACCATAGAGGGG	TLK2	ENSG00000146872	-0.7999320636638442	[3,3]	[1,0]	-9	hSpCas9	positive selection	3094845
62573242	62573265	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGAAGAGATAGAAAGACAACGG	TLK2	ENSG00000146872	-0.8867732278201942	[3,3]	[1,0]	-9	hSpCas9	positive selection	3094846
62553712	62553735	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGACTTAGAGAAGAAGGAGGG	TLK2	ENSG00000146872	0.05445795943856424	[4,4]	[3,2]	1	hSpCas9	positive selection	3094847
62523156	62523179	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAAAATTAGTGATTACTTTGAGG	TLK2	ENSG00000146872	-0.327636289275321	[191,191]	[0,0]	-2	hSpCas9	positive selection	3397335
62536316	62536339	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGAAACAAAAGTGAAGCAGAGG	TLK2	ENSG00000146872	1.449971289388231	[55,55]	[0,0]	6	hSpCas9	positive selection	3397336
62536173	62536196	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.04645453673126785	[157,157]	[0,0]	0	hSpCas9	positive selection	3397337
62536275	62536298	17	-	26780180	HT29	viability (Avana library 4 designs)	AGCTGCTCTGTGTCAAGCCGAGG	TLK2	ENSG00000146872	2.35239370399185	[]	[]	8	hSpCas9	negative selection	3465743
62536185	62536208	17	-	26780180	HT29	viability (Avana library 4 designs)	CTGCCATCTAAACCATAGAGGGG	TLK2	ENSG00000146872	2.12650729157161	[]	[]	7	hSpCas9	negative selection	3465744
62573241	62573264	17	+	26780180	HT29	viability (Avana library 4 designs)	GGGAAGAGATAGAAAGACAACGG	TLK2	ENSG00000146872	2.38364999133466	[]	[]	8	hSpCas9	negative selection	3465745
62553711	62553734	17	+	26780180	HT29	viability (Avana library 4 designs)	TCTGACTTAGAGAAGAAGGAGGG	TLK2	ENSG00000146872	1.03935947734141	[]	[]	4	hSpCas9	negative selection	3465746
62553711	62553734	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGACTTAGAGAAGAAGGAGGG	TLK2	ENSG00000146872	-8.8167454497517	[]	[]	-7	hSpCas9	negative selection	3569078
62536275	62536298	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGCTGCTCTGTGTCAAGCCGAGG	TLK2	ENSG00000146872	5.80290071668368	[]	[]	9	hSpCas9	negative selection	3569079
62573241	62573264	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGAAGAGATAGAAAGACAACGG	TLK2	ENSG00000146872	-23.789187664578	[]	[]	-9	hSpCas9	negative selection	3569080
62536185	62536208	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGCCATCTAAACCATAGAGGGG	TLK2	ENSG00000146872	-12.167898487948	[]	[]	-8	hSpCas9	negative selection	3569081
62536258	62536281	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGTGATGCTAGCAAAACCTCGG	TLK2	ENSG00000146872	-11.1798105035885	[]	[]	-8	hSpCas9	negative selection	3569082
62573221	62573244	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAAAGGATAAATTCACAGAGGG	TLK2	ENSG00000146872	-20.9558423122157	[]	[]	-9	hSpCas9	negative selection	3569083
62553711	62553734	17	+	26780180	A375	viability (Avana lentiGuide)	TCTGACTTAGAGAAGAAGGAGGG	TLK2	ENSG00000146872	7.07164184939787	[]	[]	5	hSpCas9	negative selection	3677737
62536275	62536298	17	-	26780180	A375	viability (Avana lentiGuide)	AGCTGCTCTGTGTCAAGCCGAGG	TLK2	ENSG00000146872	-0.0602160452722163	[]	[]	0	hSpCas9	negative selection	3677738
62573241	62573264	17	+	26780180	A375	viability (Avana lentiGuide)	GGGAAGAGATAGAAAGACAACGG	TLK2	ENSG00000146872	24.4073286988301	[]	[]	9	hSpCas9	negative selection	3677739
62536185	62536208	17	-	26780180	A375	viability (Avana lentiGuide)	CTGCCATCTAAACCATAGAGGGG	TLK2	ENSG00000146872	11.1807859550508	[]	[]	7	hSpCas9	negative selection	3677740
62536258	62536281	17	+	26780180	A375	viability (Avana lentiGuide)	CAGTGATGCTAGCAAAACCTCGG	TLK2	ENSG00000146872	21.4445908187174	[]	[]	9	hSpCas9	negative selection	3677741
62573221	62573244	17	+	26780180	A375	viability (Avana lentiGuide)	GGAAAGGATAAATTCACAGAGGG	TLK2	ENSG00000146872	24.8051215034299	[]	[]	9	hSpCas9	negative selection	3677742
62553711	62553734	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGACTTAGAGAAGAAGGAGGG	TLK2	ENSG00000146872	-0.6929454841271159	[7]	[2,5]	-7	hSpCas9	positive selection	3786344
62536275	62536298	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCTGCTCTGTGTCAAGCCGAGG	TLK2	ENSG00000146872	0.20256423273658491	[4]	[6,3]	5	hSpCas9	positive selection	3786345
62573241	62573264	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGAAGAGATAGAAAGACAACGG	TLK2	ENSG00000146872	-2.012777934192653	[6]	[0,0]	-9	hSpCas9	positive selection	3786346
62536185	62536208	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGCCATCTAAACCATAGAGGGG	TLK2	ENSG00000146872	-1.9470332323012458	[5]	[0,0]	-9	hSpCas9	positive selection	3786347
62536258	62536281	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGTGATGCTAGCAAAACCTCGG	TLK2	ENSG00000146872	-0.925977477077852	[5]	[2,1]	-8	hSpCas9	positive selection	3786348
62573221	62573244	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAAAGGATAAATTCACAGAGGG	TLK2	ENSG00000146872	-2.7126535669817735	[5]	[0,0]	-9	hSpCas9	positive selection	3786349
62553711	62553734	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGACTTAGAGAAGAAGGAGGG	TLK2	ENSG00000146872	-0.09538503026303982	[6]	[4,5]	-1	hSpCas9	positive selection	3894951
62536275	62536298	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCTGCTCTGTGTCAAGCCGAGG	TLK2	ENSG00000146872	-0.7532060326641775	[4]	[3,0]	-7	hSpCas9	positive selection	3894952
62573241	62573264	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGAAGAGATAGAAAGACAACGG	TLK2	ENSG00000146872	-0.9521614500100819	[5]	[2,0]	-8	hSpCas9	positive selection	3894953
62536185	62536208	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGCCATCTAAACCATAGAGGGG	TLK2	ENSG00000146872	-0.8335283494550386	[6]	[3,1]	-8	hSpCas9	positive selection	3894954
62536258	62536281	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGTGATGCTAGCAAAACCTCGG	TLK2	ENSG00000146872	-1.3137674891300957	[5]	[0,1]	-9	hSpCas9	positive selection	3894955
62573221	62573244	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAAAGGATAAATTCACAGAGGG	TLK2	ENSG00000146872	-2.2163507746650244	[4]	[0,0]	-9	hSpCas9	positive selection	3894956
62536173	62536196	17	+	26780180	A375	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	1.48065309054457	[]	[]	8	hSpCas9	negative selection	4004295
62520823	62520846	17	+	26780180	A375	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	1.20230019191855	[]	[]	6	hSpCas9	negative selection	4004296
62536173	62536196	17	+	26780180	HT29	viability (GeCKOv2 library)	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	1.49260030659062	[]	[]	7	hSpCas9	negative selection	4112261
62520823	62520846	17	+	26780180	HT29	viability (GeCKOv2 library)	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	0.406294096378476	[]	[]	1	hSpCas9	negative selection	4112262
62520823	62520846	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.4041962057134838	[2]	[1,0]	-7	hSpCas9	positive selection	4303246
62536173	62536196	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.50136857436318	[3]	[2,0]	-8	hSpCas9	positive selection	4367501
62520798	62520820	17	+	27760321	OCIAML3	viability	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-0.252405078739105	[972,780]	[542,610]	-3	hSpCas9	negative selection	4447216
62522218	62522240	17	+	27760321	OCIAML3	viability	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	-1.125597466553409	[321,259]	[101,105]	-7	hSpCas9	negative selection	4447217
62536197	62536219	17	+	27760321	OCIAML3	viability	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-1.3167513127198807	[475,365]	[115,150]	-8	hSpCas9	negative selection	4447218
62536249	62536271	17	-	27760321	OCIAML3	viability	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	-0.9276574171701737	[629,546]	[246,233]	-7	hSpCas9	negative selection	4447219
62552318	62552340	17	-	27760321	OCIAML3	viability	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-0.6590002277039649	[730,628]	[235,465]	-6	hSpCas9	negative selection	4447220
62520798	62520820	17	+	27760321	OCIAML2	viability	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-0.8756529561250451	[972,780]	[317,471]	-7	hSpCas9	negative selection	4530679
62522218	62522240	17	+	27760321	OCIAML2	viability	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	-0.24348882238338188	[321,259]	[148,261]	-3	hSpCas9	negative selection	4530680
62536197	62536219	17	+	27760321	OCIAML2	viability	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-1.380892321478933	[475,365]	[137,118]	-8	hSpCas9	negative selection	4530681
62536249	62536271	17	-	27760321	OCIAML2	viability	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	0.024775537235164735	[629,546]	[404,585]	0	hSpCas9	negative selection	4530682
62552318	62552340	17	-	27760321	OCIAML2	viability	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-1.0128259795739274	[730,628]	[254,293]	-7	hSpCas9	negative selection	4530683
62520798	62520820	17	+	27760321	MV411	viability	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-1.4585156667855697	[972,780]	[186,242]	-7	hSpCas9	negative selection	4614142
62522218	62522240	17	+	27760321	MV411	viability	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	0.07777219631197019	[321,259]	[153,272]	0	hSpCas9	negative selection	4614143
62536197	62536219	17	+	27760321	MV411	viability	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-0.337668648297784	[475,365]	[226,204]	-2	hSpCas9	negative selection	4614144
62536249	62536271	17	-	27760321	MV411	viability	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	-0.3255043157325076	[629,546]	[231,424]	-2	hSpCas9	negative selection	4614145
62552318	62552340	17	-	27760321	MV411	viability	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-0.2061674807185675	[730,628]	[219,639]	-1	hSpCas9	negative selection	4614146
62520798	62520820	17	+	27760321	HL60	viability	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-1.03751405323352	[972,780]	[330,363]	-7	hSpCas9	negative selection	4697605
62522218	62522240	17	+	27760321	HL60	viability	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	-0.5300835030377093	[321,259]	[170,155]	-5	hSpCas9	negative selection	4697606
62536197	62536219	17	+	27760321	HL60	viability	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-1.6071466869201925	[475,365]	[96,127]	-8	hSpCas9	negative selection	4697607
62536249	62536271	17	-	27760321	HL60	viability	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	-1.1043558409448115	[629,546]	[190,256]	-8	hSpCas9	negative selection	4697608
62552318	62552340	17	-	27760321	HL60	viability	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-0.5853829725464195	[730,628]	[257,486]	-6	hSpCas9	negative selection	4697609
62520798	62520820	17	+	27760321	HT1080	viability	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-1.7414205570340218	[780,609]	[58,108]	-6	hSpCas9	negative selection	4781068
62522218	62522240	17	+	27760321	HT1080	viability	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	0.4668531065939361	[259,202]	[73,185]	2	hSpCas9	negative selection	4781069
62536197	62536219	17	+	27760321	HT1080	viability	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-0.2549592004980594	[365,285]	[115,100]	-1	hSpCas9	negative selection	4781070
62536249	62536271	17	-	27760321	HT1080	viability	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	0.6858903915134844	[546,426]	[250,378]	3	hSpCas9	negative selection	4781071
62552318	62552340	17	-	27760321	HT1080	viability	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-3.11093646435963	[628,490]	[0,52]	-7	hSpCas9	negative selection	4781072
62520798	62520820	17	+	27760321	HT29	viability after 7 days	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-0.273961740103294	[780,609]	[992,494,764]	-4	hSpCas9	negative selection	4864531
62522218	62522240	17	+	27760321	HT29	viability after 7 days	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	0.14681912330946784	[259,202]	[401,442,158]	2	hSpCas9	negative selection	4864532
62536197	62536219	17	+	27760321	HT29	viability after 7 days	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-0.8187999235826988	[365,285]	[325,219,180]	-8	hSpCas9	negative selection	4864533
62536249	62536271	17	-	27760321	HT29	viability after 7 days	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	0.03194044496332793	[546,426]	[724,735,475]	0	hSpCas9	negative selection	4864534
62552318	62552340	17	-	27760321	HT29	viability after 7 days	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-0.770503567684445	[628,490]	[522,429,329]	-8	hSpCas9	negative selection	4864535
62520798	62520820	17	+	27760321	HT29	viability after 25 days	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-0.7874026625226717	[780,609]	[344,523,525]	-6	hSpCas9	negative selection	4947994
62522218	62522240	17	+	27760321	HT29	viability after 25 days	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	-0.9739180098628009	[259,202]	[118,175,106]	-6	hSpCas9	negative selection	4947995
62536197	62536219	17	+	27760321	HT29	viability after 25 days	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-1.8861126758745372	[365,285]	[33,209,57]	-8	hSpCas9	negative selection	4947996
62536249	62536271	17	-	27760321	HT29	viability after 25 days	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	-0.17530890569316754	[546,426]	[607,538,303]	-2	hSpCas9	negative selection	4947997
62552318	62552340	17	-	27760321	HT29	viability after 25 days	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-0.5481352532861591	[628,490]	[597,320,376]	-5	hSpCas9	negative selection	4947998
62520798	62520820	17	+	27760321	HT29	viability after 22 days	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-0.9164968731823836	[780,609]	[355,481,441]	-6	hSpCas9	negative selection	5031457
62522218	62522240	17	+	27760321	HT29	viability after 22 days	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	-0.5389272241310035	[259,202]	[160,232,158]	-5	hSpCas9	negative selection	5031458
62536197	62536219	17	+	27760321	HT29	viability after 22 days	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-1.2832987454763998	[365,285]	[103,198,162]	-7	hSpCas9	negative selection	5031459
62536249	62536271	17	-	27760321	HT29	viability after 22 days	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	-0.3584548923164074	[546,426]	[469,571,272]	-4	hSpCas9	negative selection	5031460
62552318	62552340	17	-	27760321	HT29	viability after 22 days	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-0.5364524672062622	[628,490]	[564,516,251]	-5	hSpCas9	negative selection	5031461
62520798	62520820	17	+	27760321	HT29	viability after 19 days	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-0.5248221165549489	[780,609]	[661,328,673]	-4	hSpCas9	negative selection	5114920
62522218	62522240	17	+	27760321	HT29	viability after 19 days	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	-0.03398188568176708	[259,202]	[152,256,350]	0	hSpCas9	negative selection	5114921
62536197	62536219	17	+	27760321	HT29	viability after 19 days	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-1.4816481724483728	[365,285]	[117,124,154]	-7	hSpCas9	negative selection	5114922
62536249	62536271	17	-	27760321	HT29	viability after 19 days	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	0.5875757343308603	[546,426]	[792,479,1217]	6	hSpCas9	negative selection	5114923
62552318	62552340	17	-	27760321	HT29	viability after 19 days	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-1.382063838536753	[628,490]	[493,183,90]	-7	hSpCas9	negative selection	5114924
62520798	62520820	17	+	27760321	HT29	viability after 16 days	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-0.4623913400632211	[780,609]	[370,638,663]	-5	hSpCas9	negative selection	5198383
62522218	62522240	17	+	27760321	HT29	viability after 16 days	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	-1.678352339422111	[259,202]	[66,97,75]	-8	hSpCas9	negative selection	5198384
62536197	62536219	17	+	27760321	HT29	viability after 16 days	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-1.2732966117384317	[365,285]	[203,177,74]	-7	hSpCas9	negative selection	5198385
62536249	62536271	17	-	27760321	HT29	viability after 16 days	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	-0.1793783972612334	[546,426]	[726,466,272]	-2	hSpCas9	negative selection	5198386
62552318	62552340	17	-	27760321	HT29	viability after 16 days	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-0.6424727711947286	[628,490]	[568,434,214]	-6	hSpCas9	negative selection	5198387
62520798	62520820	17	+	27760321	HT29	viability after 13 days	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-0.34742783092090745	[780,609]	[707,673,526]	-4	hSpCas9	negative selection	5281846
62522218	62522240	17	+	27760321	HT29	viability after 13 days	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	-0.3602842051211801	[259,202]	[241,132,249]	-4	hSpCas9	negative selection	5281847
62536197	62536219	17	+	27760321	HT29	viability after 13 days	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-0.6550018241754617	[365,285]	[214,271,233]	-6	hSpCas9	negative selection	5281848
62536249	62536271	17	-	27760321	HT29	viability after 13 days	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	-0.303734126220567	[546,426]	[374,518,477]	-4	hSpCas9	negative selection	5281849
62552318	62552340	17	-	27760321	HT29	viability after 13 days	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-0.7334185805500495	[628,490]	[487,446,245]	-6	hSpCas9	negative selection	5281850
62520798	62520820	17	+	27760321	HT29	viability after 10 days	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-0.3041968429408043	[780,609]	[748,665,693]	-4	hSpCas9	negative selection	5365309
62522218	62522240	17	+	27760321	HT29	viability after 10 days	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	-0.6350789600237976	[259,202]	[220,183,153]	-6	hSpCas9	negative selection	5365310
62536197	62536219	17	+	27760321	HT29	viability after 10 days	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-0.8196801476496827	[365,285]	[265,237,188]	-7	hSpCas9	negative selection	5365311
62536249	62536271	17	-	27760321	HT29	viability after 10 days	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	-0.07547519986379309	[546,426]	[681,367,672]	-1	hSpCas9	negative selection	5365312
62552318	62552340	17	-	27760321	HT29	viability after 10 days	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	-0.6882752018332478	[628,490]	[453,330,511]	-7	hSpCas9	negative selection	5365313
62520798	62520820	17	+	27760321	MOLM13	viability	ACCAGAGCTTGTGCAGCGTCGG	TLK2	ENSG00000146872	-1.0018194526425235	[972,780]	[249,241]	-5	hSpCas9	negative selection	5448772
62522218	62522240	17	+	27760321	MOLM13	viability	GCAGAATGACCAGCGAAATCGG	TLK2	ENSG00000146872	-1.252827682864031	[321,259]	[74,62]	-6	hSpCas9	negative selection	5448773
62536197	62536219	17	+	27760321	MOLM13	viability	TTAGATGGCAGTGCTGCAAAGG	TLK2	ENSG00000146872	-1.094628740314143	[475,365]	[57,154]	-6	hSpCas9	negative selection	5448774
62536249	62536271	17	-	27760321	MOLM13	viability	GCTAGCATCACTGACATGAGGG	TLK2	ENSG00000146872	0.0010925264835535131	[629,546]	[237,410]	0	hSpCas9	negative selection	5448775
62552318	62552340	17	-	27760321	MOLM13	viability	TTGCCAGATCCCGTAGATGAGG	TLK2	ENSG00000146872	0.041855049802258404	[730,628]	[86,654]	0	hSpCas9	negative selection	5448776
62479031	62479054	17	+	27661255	K562	viability	GCCCGGGCCCGGGCCCGCGTCGG	TLK2	ENSG00000146872	0.36484607063734753	[45,63]	[79,35]	9	dCas9-KRAB	negative selection	5517512
62479312	62479335	17	+	27661255	K562	viability	GGGGGAGGACTCCAGGCCTGGGG	TLK2	ENSG00000146872	-0.06280169744261077	[1247,1180]	[1027,845]	-2	dCas9-KRAB	negative selection	5517513
62479518	62479541	17	+	27661255	K562	viability	GGCGGCCGGAGGAGAGACGGGGG	TLK2	ENSG00000146872	-0.26434537809412717	[134,95]	[86,68]	-6	dCas9-KRAB	negative selection	5517514
62479526	62479549	17	+	27661255	K562	viability	GAGGAGAGACGGGGGCCCCCAGG	TLK2	ENSG00000146872	-0.14977383245177112	[1102,1125]	[880,734]	-5	dCas9-KRAB	negative selection	5517515
62479341	62479364	17	-	27661255	K562	viability	GGCCAAAGGGGTCCCCAGGACGG	TLK2	ENSG00000146872	-0.2557253959406236	[429,581]	[360,315]	-6	dCas9-KRAB	negative selection	5517516
62479353	62479376	17	-	27661255	K562	viability	GCAGGCTCCTCAGGCCAAAGGGG	TLK2	ENSG00000146872	-0.3367904698013495	[408,374]	[243,251]	-7	dCas9-KRAB	negative selection	5517517
62520823	62520846	17	+	27260156	BXPC3	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.2188551587994294	[258]	[193,188,243,319]	-5	hSpCas9	negative selection	5575706
62536173	62536196	17	+	27260156	BXPC3	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.010398346327170009	[480]	[365,495,593,561]	0	hSpCas9	negative selection	5639961
62520823	62520846	17	+	27260156	A673	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	0.030645571845366315	[258]	[345,321,308,294]	0	hSpCas9	negative selection	5696957
62536173	62536196	17	+	27260156	A673	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.010702616225974987	[480]	[533,591,584,575]	0	hSpCas9	negative selection	5761212
62520823	62520846	17	+	27260156	A375	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.5298853257679583	[258]	[241,265,179,162]	-6	hSpCas9	negative selection	5818208
62536173	62536196	17	+	27260156	A375	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.6362362423310955	[480]	[442,399,417,207]	-7	hSpCas9	negative selection	5882463
62520823	62520846	17	+	27260156	COLO741	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.3511299651049591	[258]	[252,275,248]	-6	hSpCas9	negative selection	5939459
62536173	62536196	17	+	27260156	COLO741	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.022153371695694576	[480]	[586,776,459]	0	hSpCas9	negative selection	6003714
62520823	62520846	17	+	27260156	CAL120	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.5389954937329824	[258]	[230,171,262]	-6	hSpCas9	negative selection	6060710
62536173	62536196	17	+	27260156	CAL120	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.0922429250444064	[480]	[786,529,403]	-1	hSpCas9	negative selection	6124965
62520823	62520846	17	+	27260156	CADOES1	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.4835593861698688	[258]	[189,201,128,167]	-7	hSpCas9	negative selection	6181961
62536173	62536196	17	+	27260156	CADOES1	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.6703998204865563	[480]	[352,182,305,281]	-8	hSpCas9	negative selection	6246216
62520823	62520846	17	+	27260156	EWS502	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.36358007679207427	[258]	[279,150,174,241]	-6	hSpCas9	negative selection	6303212
62536173	62536196	17	+	27260156	EWS502	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.5805312188477575	[480]	[253,222,478,428]	-7	hSpCas9	negative selection	6367467
62520823	62520846	17	+	27260156	EW8	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	0.42577635891937116	[258]	[273,205,368,261]	7	hSpCas9	negative selection	6424463
62536173	62536196	17	+	27260156	EW8	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.5316277316707219	[480]	[289,343,135,332]	-7	hSpCas9	negative selection	6488718
62520823	62520846	17	+	27260156	CORL105	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.26207955014254436	[258]	[230,294,322,171]	-5	hSpCas9	negative selection	6545714
62536173	62536196	17	+	27260156	CORL105	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.6238270277280415	[480]	[392,304,411,360]	-8	hSpCas9	negative selection	6609969
62520823	62520846	17	+	27260156	HS294T	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.13930300917471328	[258]	[84,75,114,87]	-2	hSpCas9	negative selection	6666965
62536173	62536196	17	+	27260156	HS294T	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.07579159587485221	[480]	[148,147,244,164]	-1	hSpCas9	negative selection	6731220
62520823	62520846	17	+	27260156	HCC44	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	0.197873858195872	[258]	[315,369,424,241]	3	hSpCas9	negative selection	6788216
62536173	62536196	17	+	27260156	HCC44	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.019633669371135296	[480]	[703,340,685,481]	0	hSpCas9	negative selection	6852471
62520823	62520846	17	+	27260156	G402	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.17716257866611285	[258]	[280,287,254,292]	-2	hSpCas9	negative selection	6909467
62536173	62536196	17	+	27260156	G402	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.5260366898363389	[480]	[423,278,625,299]	-6	hSpCas9	negative selection	6973722
62520823	62520846	17	+	27260156	L33	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.20685137483970117	[258]	[209,79,205,165]	-5	hSpCas9	negative selection	7030718
62536173	62536196	17	+	27260156	L33	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	0.154797698644078	[480]	[556,181,370,549]	3	hSpCas9	negative selection	7094973
62520823	62520846	17	+	27260156	K562	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.39284322054529164	[258]	[142,243,133,178]	-5	hSpCas9	negative selection	7151969
62536173	62536196	17	+	27260156	K562	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.16016569286151688	[480]	[215,400,365,514]	-2	hSpCas9	negative selection	7216224
62520823	62520846	17	+	27260156	HT29	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	0.09508806147689741	[258]	[474,423,287,191]	1	hSpCas9	negative selection	7273220
62536173	62536196	17	+	27260156	HT29	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.7179005278343468	[480]	[395,261,342,406]	-8	hSpCas9	negative selection	7337475
62520823	62520846	17	+	27260156	MHHES1	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.4188785109377844	[258]	[164,224,242,226]	-7	hSpCas9	negative selection	7394471
62536173	62536196	17	+	27260156	MHHES1	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.5453602277548271	[480]	[495,351,321,328]	-7	hSpCas9	negative selection	7458726
62520823	62520846	17	+	27260156	MEWO	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.4317257905016798	[258]	[200,184,156]	-7	hSpCas9	negative selection	7515722
62536173	62536196	17	+	27260156	MEWO	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	0.09179446769455445	[480]	[533,508,405]	2	hSpCas9	negative selection	7579977
62520823	62520846	17	+	27260156	LNCAPCLONEFGC	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.5101481909362586	[258]	[177,149,187,146]	-7	hSpCas9	negative selection	7636973
62536173	62536196	17	+	27260156	LNCAPCLONEFGC	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.5428112448505341	[480]	[267,296,319,314]	-7	hSpCas9	negative selection	7701228
62520823	62520846	17	+	27260156	PANC0327	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.2801170069701868	[258]	[265,66,247,198]	-4	hSpCas9	negative selection	7758224
62536173	62536196	17	+	27260156	PANC0327	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.26068574461605404	[480]	[393,428,243,352]	-4	hSpCas9	negative selection	7822479
62520823	62520846	17	+	27260156	NCIH2009	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-1.412900574505862	[258]	[72,192,127]	-9	hSpCas9	negative selection	7879475
62536173	62536196	17	+	27260156	NCIH2009	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.9929052159135202	[480]	[420,332,274]	-8	hSpCas9	negative selection	7943730
62520823	62520846	17	+	27260156	NCIH1373	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-1.3894302072366944	[258]	[91,17,79,70]	-8	hSpCas9	negative selection	8000726
62536173	62536196	17	+	27260156	NCIH1373	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.9183547845759179	[480]	[266,249,301,84]	-7	hSpCas9	negative selection	8064981
62520823	62520846	17	+	27260156	PATU8902	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-2.402052224184315	[258]	[125,51,25,79]	-9	hSpCas9	negative selection	8121977
62536173	62536196	17	+	27260156	PATU8902	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-3.236263328396965	[480]	[30,192,46,12]	-9	hSpCas9	negative selection	8186232
62520823	62520846	17	+	27260156	PANC1	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.417055648605442	[258]	[128,282,109,165]	-6	hSpCas9	negative selection	8243228
62536173	62536196	17	+	27260156	PANC1	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.6095463217428682	[480]	[360,329,115,278]	-7	hSpCas9	negative selection	8307483
62520823	62520846	17	+	27260156	PANC0813	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.5889556473725985	[258]	[204,202,233,168]	-7	hSpCas9	negative selection	8364479
62536173	62536196	17	+	27260156	PANC0813	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.8610236530715545	[480]	[240,437,385,179]	-8	hSpCas9	negative selection	8428734
62520823	62520846	17	+	27260156	RDES	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.9395477468028004	[258]	[176,109,187,138]	-9	hSpCas9	negative selection	8485730
62536173	62536196	17	+	27260156	RDES	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.7228202636468193	[480]	[286,294,307,474]	-8	hSpCas9	negative selection	8549985
62520823	62520846	17	+	27260156	PC3	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	0.08287410323824529	[258]	[156,300,440,284]	2	hSpCas9	negative selection	8606981
62536173	62536196	17	+	27260156	PC3	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	0.14804371879671058	[480]	[287,466,963,644]	3	hSpCas9	negative selection	8671236
62520823	62520846	17	+	27260156	PATU8988T	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	0.2546113989478127	[258]	[299,286,434,157]	4	hSpCas9	negative selection	8728232
62536173	62536196	17	+	27260156	PATU8988T	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.7305662057512661	[480]	[219,328,263,314]	-8	hSpCas9	negative selection	8792487
62520823	62520846	17	+	27260156	T47D	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	0.029999934817456775	[258]	[327,258,381,264]	0	hSpCas9	negative selection	8849483
62536173	62536196	17	+	27260156	T47D	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.32309637361063753	[480]	[428,415,447,502]	-6	hSpCas9	negative selection	8913738
62520823	62520846	17	+	27260156	SU8686	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.48498977735172266	[258]	[227,129,190,185]	-6	hSpCas9	negative selection	8970734
62536173	62536196	17	+	27260156	SU8686	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.7146337118535513	[480]	[266,286,220,404]	-8	hSpCas9	negative selection	9034989
62520823	62520846	17	+	27260156	SKES1	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.18953795811052676	[258]	[226,171,211,279]	-4	hSpCas9	negative selection	9091985
62536173	62536196	17	+	27260156	SKES1	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	0.006719015648659919	[480]	[593,377,521,436]	0	hSpCas9	negative selection	9156240
62520823	62520846	17	+	27260156	TOV112D	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.06030490117695886	[258]	[376,211,286,123]	-1	hSpCas9	negative selection	9213236
62536173	62536196	17	+	27260156	TOV112D	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.38877541137083405	[480]	[288,507,297,402]	-6	hSpCas9	negative selection	9277491
62520823	62520846	17	+	27260156	TC71	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	0.053054578704987865	[258]	[286,224,340,297]	1	hSpCas9	negative selection	9334487
62536173	62536196	17	+	27260156	TC71	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.0909501342864279	[480]	[435,539,493,465]	-2	hSpCas9	negative selection	9398742
62520823	62520846	17	+	27260156	TC32	viability	CTTGAGTGATAAAGAAGTAGAGG	TLK2	ENSG00000146872	-0.37849269873886815	[258]	[171,189,223,155]	-6	hSpCas9	negative selection	9455738
62536173	62536196	17	+	27260156	TC32	viability	CGAGTAGAACAGCCCCTCTATGG	TLK2	ENSG00000146872	-0.39825466720406144	[480]	[336,303,344,381]	-6	hSpCas9	negative selection	9519993
62565083	62565106	17	+	28162770	P31FUJ	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	-0.40717311088788316	[324]	[287]	-4	hSpCas9	negative selection	10251161
62600716	62600739	17	+	28162770	P31FUJ	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	0.21345402547518533	[79]	[108]	2	hSpCas9	negative selection	10251162
62573205	62573228	17	+	28162770	P31FUJ	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.9873236099501244	[181]	[423]	9	hSpCas9	negative selection	10251163
62578497	62578520	17	+	28162770	P31FUJ	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-0.504104226231773	[104]	[86]	-4	hSpCas9	negative selection	10251164
62606220	62606243	17	+	28162770	P31FUJ	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	-0.09641373549843124	[352]	[387]	-1	hSpCas9	negative selection	10251165
62578473	62578496	17	+	28162770	P31FUJ	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-1.1718732057720467	[509]	[265]	-7	hSpCas9	negative selection	10251166
62602053	62602076	17	+	28162770	P31FUJ	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	-0.17390851536080998	[359]	[374]	-2	hSpCas9	negative selection	10251167
62608119	62608142	17	-	28162770	P31FUJ	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	0.2852292881877907	[749]	[1073]	3	hSpCas9	negative selection	10251168
62612473	62612496	17	-	28162770	P31FUJ	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-0.10950771254875469	[806]	[878]	-1	hSpCas9	negative selection	10251169
62573330	62573353	17	+	28162770	P31FUJ	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-0.15661264123793572	[460]	[485]	-1	hSpCas9	negative selection	10251170
62565083	62565106	17	+	28162770	TF1	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	NaN	[NaN]	[252]	1	hSpCas9	negative selection	10420527
62600716	62600739	17	+	28162770	TF1	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	NaN	[NaN]	[184]	1	hSpCas9	negative selection	10420528
62573205	62573228	17	+	28162770	TF1	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10420529
62578497	62578520	17	+	28162770	TF1	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10420530
62606220	62606243	17	+	28162770	TF1	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	NaN	[NaN]	[444]	1	hSpCas9	negative selection	10420531
62578473	62578496	17	+	28162770	TF1	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	NaN	[NaN]	[213]	1	hSpCas9	negative selection	10420532
62602053	62602076	17	+	28162770	TF1	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	NaN	[NaN]	[364]	1	hSpCas9	negative selection	10420533
62608119	62608142	17	-	28162770	TF1	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	NaN	[NaN]	[755]	1	hSpCas9	negative selection	10420534
62612473	62612496	17	-	28162770	TF1	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	NaN	[NaN]	[990]	1	hSpCas9	negative selection	10420535
62573330	62573353	17	+	28162770	TF1	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	NaN	[NaN]	[191]	1	hSpCas9	negative selection	10420536
62565083	62565106	17	+	28162770	SKM1	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.6502312028383812	[101]	[282]	6	hSpCas9	negative selection	10589893
62600716	62600739	17	+	28162770	SKM1	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	-0.06992921146559095	[18]	[31]	0	hSpCas9	negative selection	10589894
62573205	62573228	17	+	28162770	SKM1	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.21864028647534045	[69]	[143]	2	hSpCas9	negative selection	10589895
62578497	62578520	17	+	28162770	SKM1	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-0.1147834472498514	[48]	[79]	-1	hSpCas9	negative selection	10589896
62606220	62606243	17	+	28162770	SKM1	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.8474111244984622	[93]	[298]	7	hSpCas9	negative selection	10589897
62578473	62578496	17	+	28162770	SKM1	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-0.1255787668123063	[165]	[268]	-1	hSpCas9	negative selection	10589898
62602053	62602076	17	+	28162770	SKM1	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	0.5424097281868703	[86]	[223]	5	hSpCas9	negative selection	10589899
62608119	62608142	17	-	28162770	SKM1	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	0.8884916847830098	[120]	[395]	8	hSpCas9	negative selection	10589900
62612473	62612496	17	-	28162770	SKM1	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	0.46358454980163644	[200]	[489]	4	hSpCas9	negative selection	10589901
62573330	62573353	17	+	28162770	SKM1	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-0.21194821633801875	[94]	[144]	-2	hSpCas9	negative selection	10589902
62565083	62565106	17	+	28162770	SKM1	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.6502312028383812	[101]	[282]	6	hSpCas9	negative selection	10759259
62600716	62600739	17	+	28162770	SKM1	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	-0.06992921146559095	[18]	[31]	0	hSpCas9	negative selection	10759260
62573205	62573228	17	+	28162770	SKM1	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.21864028647534045	[69]	[143]	2	hSpCas9	negative selection	10759261
62578497	62578520	17	+	28162770	SKM1	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-0.1147834472498514	[48]	[79]	-1	hSpCas9	negative selection	10759262
62606220	62606243	17	+	28162770	SKM1	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.8474111244984622	[93]	[298]	7	hSpCas9	negative selection	10759263
62578473	62578496	17	+	28162770	SKM1	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-0.1255787668123063	[165]	[268]	-1	hSpCas9	negative selection	10759264
62602053	62602076	17	+	28162770	SKM1	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	0.5424097281868703	[86]	[223]	5	hSpCas9	negative selection	10759265
62608119	62608142	17	-	28162770	SKM1	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	0.8884916847830098	[120]	[395]	8	hSpCas9	negative selection	10759266
62612473	62612496	17	-	28162770	SKM1	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	0.46358454980163644	[200]	[489]	4	hSpCas9	negative selection	10759267
62573330	62573353	17	+	28162770	SKM1	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-0.21194821633801875	[94]	[144]	-2	hSpCas9	negative selection	10759268
62565083	62565106	17	+	28162770	PL21	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.02701218100866387	[450]	[199]	0	hSpCas9	negative selection	10928625
62600716	62600739	17	+	28162770	PL21	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	0.09777789685964211	[72]	[33]	0	hSpCas9	negative selection	10928626
62573205	62573228	17	+	28162770	PL21	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.7424577778019826	[205]	[149]	6	hSpCas9	negative selection	10928627
62578497	62578520	17	+	28162770	PL21	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-1.3962276495040853	[126]	[20]	-7	hSpCas9	negative selection	10928628
62606220	62606243	17	+	28162770	PL21	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	-0.26421420285270314	[366]	[132]	-2	hSpCas9	negative selection	10928629
62578473	62578496	17	+	28162770	PL21	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-1.227281609245356	[623]	[115]	-7	hSpCas9	negative selection	10928630
62602053	62602076	17	+	28162770	PL21	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	-0.34622004700808884	[294]	[100]	-2	hSpCas9	negative selection	10928631
62608119	62608142	17	-	28162770	PL21	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	-0.035308959672574414	[517]	[219]	0	hSpCas9	negative selection	10928632
62612473	62612496	17	-	28162770	PL21	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-0.27924011837483853	[618]	[221]	-2	hSpCas9	negative selection	10928633
62573330	62573353	17	+	28162770	PL21	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	0.058270898177983255	[330]	[149]	0	hSpCas9	negative selection	10928634
62565083	62565106	17	+	28162770	P31FUJ	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	-0.40717311088788316	[324]	[287]	-4	hSpCas9	negative selection	11097991
62600716	62600739	17	+	28162770	P31FUJ	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	0.21345402547518533	[79]	[108]	2	hSpCas9	negative selection	11097992
62573205	62573228	17	+	28162770	P31FUJ	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.9873236099501244	[181]	[423]	9	hSpCas9	negative selection	11097993
62578497	62578520	17	+	28162770	P31FUJ	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-0.504104226231773	[104]	[86]	-4	hSpCas9	negative selection	11097994
62606220	62606243	17	+	28162770	P31FUJ	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	-0.09641373549843124	[352]	[387]	-1	hSpCas9	negative selection	11097995
62578473	62578496	17	+	28162770	P31FUJ	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-1.1718732057720467	[509]	[265]	-7	hSpCas9	negative selection	11097996
62602053	62602076	17	+	28162770	P31FUJ	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	-0.17390851536080998	[359]	[374]	-2	hSpCas9	negative selection	11097997
62608119	62608142	17	-	28162770	P31FUJ	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	0.2852292881877907	[749]	[1073]	3	hSpCas9	negative selection	11097998
62612473	62612496	17	-	28162770	P31FUJ	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-0.10950771254875469	[806]	[878]	-1	hSpCas9	negative selection	11097999
62573330	62573353	17	+	28162770	P31FUJ	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-0.15661264123793572	[460]	[485]	-1	hSpCas9	negative selection	11098000
62565083	62565106	17	+	28162770	OCIAML5	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.525131122389177	[168]	[438]	4	hSpCas9	negative selection	11267357
62600716	62600739	17	+	28162770	OCIAML5	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	-0.0971790687005285	[63]	[107]	0	hSpCas9	negative selection	11267358
62573205	62573228	17	+	28162770	OCIAML5	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.6714953851930159	[127]	[367]	6	hSpCas9	negative selection	11267359
62578497	62578520	17	+	28162770	OCIAML5	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	0.19855950220597118	[41]	[86]	1	hSpCas9	negative selection	11267360
62606220	62606243	17	+	28162770	OCIAML5	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.6333602563062446	[184]	[517]	5	hSpCas9	negative selection	11267361
62578473	62578496	17	+	28162770	OCIAML5	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-0.7040654079764432	[360]	[399]	-4	hSpCas9	negative selection	11267362
62602053	62602076	17	+	28162770	OCIAML5	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	0.6117594923555244	[148]	[410]	5	hSpCas9	negative selection	11267363
62608119	62608142	17	-	28162770	OCIAML5	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	0.30851419959035775	[326]	[730]	2	hSpCas9	negative selection	11267364
62612473	62612496	17	-	28162770	OCIAML5	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	0.7638752345545945	[429]	[1317]	6	hSpCas9	negative selection	11267365
62573330	62573353	17	+	28162770	OCIAML5	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-0.49413352252114084	[276]	[354]	-3	hSpCas9	negative selection	11267366
62565083	62565106	17	+	28162770	EOL1	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.17947712776727331	[594]	[354]	1	hSpCas9	negative selection	11436723
62600716	62600739	17	+	28162770	EOL1	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	0.5919724324836635	[67]	[53]	5	hSpCas9	negative selection	11436724
62573205	62573228	17	+	28162770	EOL1	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	-0.14066988787594611	[361]	[172]	-1	hSpCas9	negative selection	11436725
62578497	62578520	17	+	28162770	EOL1	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-0.3572231968448452	[247]	[101]	-3	hSpCas9	negative selection	11436726
62606220	62606243	17	+	28162770	EOL1	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.34165959908723686	[694]	[463]	3	hSpCas9	negative selection	11436727
62578473	62578496	17	+	28162770	EOL1	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-1.4954355503131116	[973]	[181]	-7	hSpCas9	negative selection	11436728
62602053	62602076	17	+	28162770	EOL1	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	0.009112066829007226	[380]	[201]	0	hSpCas9	negative selection	11436729
62608119	62608142	17	-	28162770	EOL1	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	0.4077567734909575	[557]	[389]	4	hSpCas9	negative selection	11436730
62612473	62612496	17	-	28162770	EOL1	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	0.49988157109391396	[901]	[671]	4	hSpCas9	negative selection	11436731
62573330	62573353	17	+	28162770	EOL1	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-0.46944428290047996	[430]	[163]	-3	hSpCas9	negative selection	11436732
62565083	62565106	17	+	28162770	MOLM13	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.3500528912507206	[509]	[469]	2	hSpCas9	negative selection	11606089
62600716	62600739	17	+	28162770	MOLM13	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	-0.4898823830661241	[100]	[51]	-3	hSpCas9	negative selection	11606090
62573205	62573228	17	+	28162770	MOLM13	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.29849004782201505	[342]	[304]	2	hSpCas9	negative selection	11606091
62578497	62578520	17	+	28162770	MOLM13	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-0.591611630204083	[197]	[94]	-3	hSpCas9	negative selection	11606092
62606220	62606243	17	+	28162770	MOLM13	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.24135326648095512	[522]	[446]	1	hSpCas9	negative selection	11606093
62578473	62578496	17	+	28162770	MOLM13	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	0.06934000505430404	[637]	[483]	0	hSpCas9	negative selection	11606094
62602053	62602076	17	+	28162770	MOLM13	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	0.03979572944028881	[369]	[274]	0	hSpCas9	negative selection	11606095
62608119	62608142	17	-	28162770	MOLM13	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	-0.013860616516313318	[626]	[448]	0	hSpCas9	negative selection	11606096
62612473	62612496	17	-	28162770	MOLM13	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-0.22387187811615927	[952]	[589]	-1	hSpCas9	negative selection	11606097
62573330	62573353	17	+	28162770	MOLM13	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-0.849499553727616	[475]	[190]	-5	hSpCas9	negative selection	11606098
62565083	62565106	17	+	28162770	HEL	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	-0.30479374810550763	[431]	[223]	-2	hSpCas9	negative selection	11775455
62600716	62600739	17	+	28162770	HEL	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	0.8772040856373798	[67]	[79]	7	hSpCas9	negative selection	11775456
62573205	62573228	17	+	28162770	HEL	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.08709189810375662	[340]	[231]	0	hSpCas9	negative selection	11775457
62578497	62578520	17	+	28162770	HEL	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-0.5907512982194217	[173]	[73]	-4	hSpCas9	negative selection	11775458
62606220	62606243	17	+	28162770	HEL	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.43402134756098554	[489]	[423]	3	hSpCas9	negative selection	11775459
62578473	62578496	17	+	28162770	HEL	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	0.28016875261564866	[602]	[468]	2	hSpCas9	negative selection	11775460
62602053	62602076	17	+	28162770	HEL	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	-0.9040885398340281	[335]	[114]	-5	hSpCas9	negative selection	11775461
62608119	62608142	17	-	28162770	HEL	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	0.5542021573986995	[503]	[473]	5	hSpCas9	negative selection	11775462
62612473	62612496	17	-	28162770	HEL	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-0.33448986034098493	[879]	[446]	-2	hSpCas9	negative selection	11775463
62573330	62573353	17	+	28162770	HEL	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-0.5462949923896598	[398]	[174]	-4	hSpCas9	negative selection	11775464
62565083	62565106	17	+	28162770	MV411	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.3597999162387332	[320]	[346]	3	hSpCas9	negative selection	11944821
62600716	62600739	17	+	28162770	MV411	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	-0.5115543497134296	[43]	[25]	-4	hSpCas9	negative selection	11944822
62573205	62573228	17	+	28162770	MV411	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.5937155070858864	[187]	[238]	5	hSpCas9	negative selection	11944823
62578497	62578520	17	+	28162770	MV411	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-1.349206754986016	[123]	[40]	-7	hSpCas9	negative selection	11944824
62606220	62606243	17	+	28162770	MV411	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.235972364289321	[378]	[375]	2	hSpCas9	negative selection	11944825
62578473	62578496	17	+	28162770	MV411	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-0.5115543497134298	[571]	[337]	-4	hSpCas9	negative selection	11944826
62602053	62602076	17	+	28162770	MV411	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	-0.050014452108380125	[262]	[213]	0	hSpCas9	negative selection	11944827
62608119	62608142	17	-	28162770	MV411	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	1.1893804491930025	[430]	[827]	9	hSpCas9	negative selection	11944828
62612473	62612496	17	-	28162770	MV411	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	0.5351809437886226	[520]	[635]	5	hSpCas9	negative selection	11944829
62573330	62573353	17	+	28162770	MV411	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-0.37047537173966744	[309]	[201]	-3	hSpCas9	negative selection	11944830
62565083	62565106	17	+	28162770	MONOMAC1	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.007103869720671341	[249]	[287]	0	hSpCas9	negative selection	12114187
62600716	62600739	17	+	28162770	MONOMAC1	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	-0.47005534146597006	[28]	[23]	-4	hSpCas9	negative selection	12114188
62573205	62573228	17	+	28162770	MONOMAC1	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	0.1170717433685094	[147]	[183]	1	hSpCas9	negative selection	12114189
62578497	62578520	17	+	28162770	MONOMAC1	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-1.741357363283364	[69]	[23]	-8	hSpCas9	negative selection	12114190
62606220	62606243	17	+	28162770	MONOMAC1	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.4316470310909204	[259]	[401]	4	hSpCas9	negative selection	12114191
62578473	62578496	17	+	28162770	MONOMAC1	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-0.35443475062570307	[386]	[346]	-3	hSpCas9	negative selection	12114192
62602053	62602076	17	+	28162770	MONOMAC1	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	-0.6092315965695723	[168]	[126]	-5	hSpCas9	negative selection	12114193
62608119	62608142	17	-	28162770	MONOMAC1	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	0.39123838770243813	[289]	[435]	4	hSpCas9	negative selection	12114194
62612473	62612496	17	-	28162770	MONOMAC1	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-0.3196561337235093	[404]	[371]	-3	hSpCas9	negative selection	12114195
62573330	62573353	17	+	28162770	MONOMAC1	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	0.03513659506947975	[188]	[221]	0	hSpCas9	negative selection	12114196
62565083	62565106	17	+	28162770	OCIAML2	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	0.3550646875183766	[66]	[474]	3	hSpCas9	negative selection	12283553
62600716	62600739	17	+	28162770	OCIAML2	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	1.367313416648866	[9]	[142]	9	hSpCas9	negative selection	12283554
62573205	62573228	17	+	28162770	OCIAML2	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	1.3019596786547663	[47]	[655]	9	hSpCas9	negative selection	12283555
62578497	62578520	17	+	28162770	OCIAML2	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-0.760136442437146	[32]	[107]	-5	hSpCas9	negative selection	12283556
62606220	62606243	17	+	28162770	OCIAML2	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	0.3970099542838632	[76]	[561]	4	hSpCas9	negative selection	12283557
62578473	62578496	17	+	28162770	OCIAML2	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	0.23902842292830973	[95]	[627]	2	hSpCas9	negative selection	12283558
62602053	62602076	17	+	28162770	OCIAML2	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	0.0716282245247567	[39]	[232]	0	hSpCas9	negative selection	12283559
62608119	62608142	17	-	28162770	OCIAML2	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	1.104279010815072	[59]	[714]	9	hSpCas9	negative selection	12283560
62612473	62612496	17	-	28162770	OCIAML2	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-0.6190216651348321	[132]	[479]	-5	hSpCas9	negative selection	12283561
62573330	62573353	17	+	28162770	OCIAML2	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	0.5711903504524658	[50]	[419]	5	hSpCas9	negative selection	12283562
62565083	62565106	17	+	28162770	OCIAML3	viability	GAGCCTCATTTACTGAACAGTGG	TLK2	ENSG00000146872	-1.287346302090111	[75]	[93]	-7	hSpCas9	negative selection	12452919
62600716	62600739	17	+	28162770	OCIAML3	viability	TAATGTCGGAGAAAGAGGCCCGG	TLK2	ENSG00000146872	0.08406426478847462	[19]	[63]	0	hSpCas9	negative selection	12452920
62573205	62573228	17	+	28162770	OCIAML3	viability	ATATCTCTAGGCAACAGGAAAGG	TLK2	ENSG00000146872	-0.6669391627780142	[70]	[134]	-5	hSpCas9	negative selection	12452921
62578497	62578520	17	+	28162770	OCIAML3	viability	AGAGCTGGAGAGACTAGAAAGGG	TLK2	ENSG00000146872	-2.433542968130917	[33]	[18]	-9	hSpCas9	negative selection	12452922
62606220	62606243	17	+	28162770	OCIAML3	viability	TCAGTGTCTTTATGGAAGGAAGG	TLK2	ENSG00000146872	-1.4072391287184367	[122]	[139]	-7	hSpCas9	negative selection	12452923
62578473	62578496	17	+	28162770	OCIAML3	viability	TTAGGAGGAAGCAGAGATCCAGG	TLK2	ENSG00000146872	-2.0557383750510483	[156]	[113]	-8	hSpCas9	negative selection	12452924
62602053	62602076	17	+	28162770	OCIAML3	viability	TTAGTAAATGGTACAGCGTGTGG	TLK2	ENSG00000146872	-1.2608813388319369	[76]	[96]	-7	hSpCas9	negative selection	12452925
62608119	62608142	17	-	28162770	OCIAML3	viability	TCAGGTGTTACTACTGGCTTTGG	TLK2	ENSG00000146872	0.36609963255232403	[109]	[427]	3	hSpCas9	negative selection	12452926
62612473	62612496	17	-	28162770	OCIAML3	viability	GAGACTGACTTTCGGATGTGAGG	TLK2	ENSG00000146872	-1.1987063591065819	[183]	[241]	-7	hSpCas9	negative selection	12452927
62573330	62573353	17	+	28162770	OCIAML3	viability	CAGCGGAAAAGCAAGACCAATGG	TLK2	ENSG00000146872	-1.2970259025670317	[104]	[128]	-7	hSpCas9	negative selection	12452928