| 19493467 | 19493490 | 13 | - | 26472758 | Jiyoye | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.5521237174169731 | [122] | [135] | 4 | hSpCas9 | negative selection | 171252 | 19465249 | 19465272 | 13 | + | 26472758 | Jiyoye | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | -0.42478672659607963 | [339] | [190] | -3 | hSpCas9 | negative selection | 171253 | 19438125 | 19438148 | 13 | + | 26472758 | Jiyoye | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | 0.19036399243272517 | [214] | [184] | 1 | hSpCas9 | negative selection | 171255 | 19438106 | 19438129 | 13 | + | 26472758 | Jiyoye | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | 1.4912396462943478 | [24] | [52] | 8 | hSpCas9 | negative selection | 171256 | 19465464 | 19465487 | 13 | - | 26472758 | Jiyoye | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 2.073057877610597 | [51] | [164] | 8 | hSpCas9 | negative selection | 171257 | 19423085 | 19423108 | 13 | - | 26472758 | Jiyoye | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.7486436627888806 | [175] | [222] | 5 | hSpCas9 | negative selection | 171258 | 19423078 | 19423101 | 13 | + | 26472758 | Jiyoye | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 1.0962462855677682 | [48] | [78] | 7 | hSpCas9 | negative selection | 171259 | 19474014 | 19474037 | 13 | + | 26472758 | Jiyoye | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.6493762839225017 | [278] | [329] | 5 | hSpCas9 | negative selection | 171260 | 19465284 | 19465307 | 13 | - | 26472758 | Jiyoye | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | 0.9041901829513269 | [123] | [174] | 6 | hSpCas9 | negative selection | 171261 | 19464475 | 19464498 | 13 | + | 26472758 | Jiyoye | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | -0.28372056396434786 | [225] | [139] | -2 | hSpCas9 | negative selection | 171263 | 19493467 | 19493490 | 13 | - | 26472758 | KBM7 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.04939759529819976 | [316,271] | [116,165] | 0 | hSpCas9 | negative selection | 362370 | 19465249 | 19465272 | 13 | + | 26472758 | KBM7 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | 0.35964269843142715 | [1164,1188] | [1029,431] | 4 | hSpCas9 | negative selection | 362371 | 19438125 | 19438148 | 13 | + | 26472758 | KBM7 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | -0.11397829962712655 | [692,504] | [250,262] | -1 | hSpCas9 | negative selection | 362373 | 19438106 | 19438129 | 13 | + | 26472758 | KBM7 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.26869671680969454 | [118,178] | [75,44] | -3 | hSpCas9 | negative selection | 362374 | 19465464 | 19465487 | 13 | - | 26472758 | KBM7 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 1.4383080708705673 | [927,496] | [917,853] | 9 | hSpCas9 | negative selection | 362375 | 19423085 | 19423108 | 13 | - | 26472758 | KBM7 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | -0.10653138405889662 | [692,593] | [389,181] | -1 | hSpCas9 | negative selection | 362376 | 19423078 | 19423101 | 13 | + | 26472758 | KBM7 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | -0.5112407392850041 | [236,291] | [95,81] | -4 | hSpCas9 | negative selection | 362377 | 19474014 | 19474037 | 13 | + | 26472758 | KBM7 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.6039151058971279 | [1262,1057] | [960,704] | 6 | hSpCas9 | negative selection | 362378 | 19465284 | 19465307 | 13 | - | 26472758 | KBM7 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | 0.17033636321037748 | [749,625] | [287,428] | 1 | hSpCas9 | negative selection | 362379 | 19464475 | 19464498 | 13 | + | 26472758 | KBM7 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 0.0992299831350365 | [664,631] | [395,265] | 1 | hSpCas9 | negative selection | 362381 | 19493467 | 19493490 | 13 | - | 26472758 | Raji | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.44948951219859223 | [141] | [44] | 4 | hSpCas9 | negative selection | 553488 | 19465249 | 19465272 | 13 | + | 26472758 | Raji | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | -0.21700859946524376 | [585] | [116] | -2 | hSpCas9 | negative selection | 553489 | 19438125 | 19438148 | 13 | + | 26472758 | Raji | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | -0.627092506766909 | [385] | [57] | -5 | hSpCas9 | negative selection | 553491 | 19438106 | 19438129 | 13 | + | 26472758 | Raji | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.19842489415048603 | [88] | [17] | -2 | hSpCas9 | negative selection | 553492 | 19465464 | 19465487 | 13 | - | 26472758 | Raji | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.6701746550961354 | [305] | [112] | 6 | hSpCas9 | negative selection | 553493 | 19423085 | 19423108 | 13 | - | 26472758 | Raji | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.7903542398990764 | [293] | [117] | 7 | hSpCas9 | negative selection | 553494 | 19423078 | 19423101 | 13 | + | 26472758 | Raji | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 0.4802955589797667 | [138] | [44] | 4 | hSpCas9 | negative selection | 553495 | 19474014 | 19474037 | 13 | + | 26472758 | Raji | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.5747155420946564 | [595] | [205] | 5 | hSpCas9 | negative selection | 553496 | 19465284 | 19465307 | 13 | - | 26472758 | Raji | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | -0.08716525303753508 | [324] | [70] | 0 | hSpCas9 | negative selection | 553497 | 19464475 | 19464498 | 13 | + | 26472758 | Raji | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 0.6995776053258315 | [397] | [149] | 6 | hSpCas9 | negative selection | 553499 | 19493467 | 19493490 | 13 | - | 26472758 | K562 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | -0.7736528452555711 | [240] | [118] | -4 | hSpCas9 | negative selection | 744606 | 19465249 | 19465272 | 13 | + | 26472758 | K562 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | -0.0745179468730246 | [1083] | [868] | 0 | hSpCas9 | negative selection | 744607 | 19438125 | 19438148 | 13 | + | 26472758 | K562 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | 0.18064281723313236 | [554] | [530] | 1 | hSpCas9 | negative selection | 744609 | 19438106 | 19438129 | 13 | + | 26472758 | K562 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.14514808409627866 | [130] | [99] | -1 | hSpCas9 | negative selection | 744610 | 19465464 | 19465487 | 13 | - | 26472758 | K562 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 1.7244662181779145 | [498] | [1391] | 9 | hSpCas9 | negative selection | 744611 | 19423085 | 19423108 | 13 | - | 26472758 | K562 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.5952443237281887 | [602] | [768] | 5 | hSpCas9 | negative selection | 744612 | 19423078 | 19423101 | 13 | + | 26472758 | K562 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 1.2651772878332441 | [137] | [279] | 9 | hSpCas9 | negative selection | 744613 | 19474014 | 19474037 | 13 | + | 26472758 | K562 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.292642674176802 | [911] | [942] | 2 | hSpCas9 | negative selection | 744614 | 19465284 | 19465307 | 13 | - | 26472758 | K562 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | 0.34767999537674366 | [592] | [636] | 2 | hSpCas9 | negative selection | 744615 | 19464475 | 19464498 | 13 | + | 26472758 | K562 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 0.1378546725993961 | [631] | [586] | 1 | hSpCas9 | negative selection | 744617 | 19497036 | 19497059 | 13 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ACAGACGGCACCTGGAAAATCGG | TPTE2 | ENSG00000132958 | 1.8780962093752518 | [249,181] | [13,347] | 6 | dCas9-VP64 | positive selection | 2401541 | 19427194 | 19427217 | 13 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCTACTTGGGAGGCTGAGGCTGG | TPTE2 | ENSG00000132958 | -0.3390870473927914 | [36,5] | [4,0] | -1 | dCas9-VP64 | positive selection | 2411852 | 19438639 | 19438662 | 13 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ACCAAGTGCCATTTCTCTTAAGG | TPTE2 | ENSG00000132958 | -1.3531381622308358 | [687,942] | [66,72] | -7 | dCas9-VP64 | positive selection | 2418778 | 19438665 | 19438688 | 13 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAAGGATGTTTTTTCCAAGATGG | TPTE2 | ENSG00000132958 | 0.4979505181253536 | [15,16] | [4,3] | 2 | dCas9-VP64 | positive selection | 2418783 | 19438647 | 19438670 | 13 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCATTTCTCTTAAGGATGCAAGG | TPTE2 | ENSG00000132958 | -1.111372974982873 | [20,211] | [2,20] | -6 | dCas9-VP64 | positive selection | 2418787 | 19528292 | 19528315 | 13 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGGAGAATCGCTTGAATCCAAG | TPTE2 | ENSG00000132958 | 1.579452491414227 | [20,39] | [3,36] | 6 | dCas9-VP64 | positive selection | 2477116 | 19497036 | 19497059 | 13 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ACAGACGGCACCTGGAAAATCGG | TPTE2 | ENSG00000132958 | 0.08411290598025589 | [220,115] | [60,55] | 0 | dCas9-VP64 | positive selection | 2496796 | 19427194 | 19427217 | 13 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCTACTTGGGAGGCTGAGGCTGG | TPTE2 | ENSG00000132958 | 0.46536086309934765 | [31,100] | [53,5] | 3 | dCas9-VP64 | positive selection | 2507107 | 19438639 | 19438662 | 13 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ACCAAGTGCCATTTCTCTTAAGG | TPTE2 | ENSG00000132958 | -0.2472821944674375 | [579,658] | [156,182] | -2 | dCas9-VP64 | positive selection | 2514033 | 19438665 | 19438688 | 13 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAAGGATGTTTTTTCCAAGATGG | TPTE2 | ENSG00000132958 | -0.2791616468172258 | [60,103] | [16,25] | -3 | dCas9-VP64 | positive selection | 2514038 | 19438647 | 19438670 | 13 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCATTTCTCTTAAGGATGCAAGG | TPTE2 | ENSG00000132958 | 2.353569241797149 | [39,227] | [21,408] | 9 | dCas9-VP64 | positive selection | 2514042 | 19528292 | 19528315 | 13 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGGAGAATCGCTTGAATCCAAG | TPTE2 | ENSG00000132958 | 0.3334805796334224 | [96,125] | [24,64] | 2 | dCas9-VP64 | positive selection | 2572371 | 19493467 | 19493490 | 13 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.05357316289700828 | [2,3] | [2,2] | 1 | hSpCas9 | positive selection | 3028848 | 19465464 | 19465487 | 13 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.0930290077547995 | [5,5] | [4,4] | 2 | hSpCas9 | positive selection | 3028849 | 19464483 | 19464506 | 13 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TGTCATTTCCATCTTCTGGAAGG | TPTE2 | ENSG00000132958 | 0.10185166635230414 | [5,5] | [5,4] | 2 | hSpCas9 | positive selection | 3028850 | 19492853 | 19492876 | 13 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TTTACTGATAGGTGACACCAGGG | TPTE2 | ENSG00000132958 | 0.13989674214214803 | [3,3] | [3,3] | 3 | hSpCas9 | positive selection | 3028851 | 19493467 | 19493490 | 13 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | -0.09756666099591557 | [2,2] | [2,1] | -1 | hSpCas9 | positive selection | 3096706 | 19465464 | 19465487 | 13 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.43264999075597715 | [5,5] | [5,4] | 7 | hSpCas9 | positive selection | 3096707 | 19464483 | 19464506 | 13 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TGTCATTTCCATCTTCTGGAAGG | TPTE2 | ENSG00000132958 | 0.1861110511563514 | [5,5] | [4,3] | 3 | hSpCas9 | positive selection | 3096708 | 19492853 | 19492876 | 13 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TTTACTGATAGGTGACACCAGGG | TPTE2 | ENSG00000132958 | 0.0725238573110342 | [3,3] | [4,1] | 1 | hSpCas9 | positive selection | 3096709 | 19492880 | 19492903 | 13 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CCACACACAAGTGAATTTAAAGG | TPTE2 | ENSG00000132958 | 1.9905396707509337 | [76,76] | [1,1] | 7 | hSpCas9 | positive selection | 3398761 | 19492849 | 19492872 | 13 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TGGTGTCACCTATCAGTAAAAGG | TPTE2 | ENSG00000132958 | -0.8564159546033534 | [276,276] | [0,0] | -6 | hSpCas9 | positive selection | 3398762 | 19493447 | 19493470 | 13 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | AGGAGGCACCTGCGAAAGAAAGG | TPTE2 | ENSG00000132958 | -0.2425196756373702 | [180,180] | [0,0] | -1 | hSpCas9 | positive selection | 3398763 | 19493467 | 19493490 | 13 | - | 26780180 | HT29 | viability (Avana library 4 designs) | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 3.41305077577241 | [] | [] | 8 | hSpCas9 | negative selection | 3467690 | 19465464 | 19465487 | 13 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.00695426369159611 | [] | [] | 0 | hSpCas9 | negative selection | 3467691 | 19464483 | 19464506 | 13 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TGTCATTTCCATCTTCTGGAAGG | TPTE2 | ENSG00000132958 | 1.0567492081987 | [] | [] | 4 | hSpCas9 | negative selection | 3467692 | 19492852 | 19492875 | 13 | + | 26780180 | HT29 | viability (Avana library 4 designs) | TTTACTGATAGGTGACACCAGGG | TPTE2 | ENSG00000132958 | 0.769674836108633 | [] | [] | 3 | hSpCas9 | negative selection | 3467693 | 19492852 | 19492875 | 13 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TTTACTGATAGGTGACACCAGGG | TPTE2 | ENSG00000132958 | -2.76330979087158 | [] | [] | -3 | hSpCas9 | negative selection | 3571984 | 19493467 | 19493490 | 13 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | -7.27521425143733 | [] | [] | -6 | hSpCas9 | negative selection | 3571985 | 19465464 | 19465487 | 13 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 4.25752966629215 | [] | [] | 7 | hSpCas9 | negative selection | 3571986 | 19464483 | 19464506 | 13 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TGTCATTTCCATCTTCTGGAAGG | TPTE2 | ENSG00000132958 | -7.9485862222752 | [] | [] | -7 | hSpCas9 | negative selection | 3571987 | 19465288 | 19465311 | 13 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AAACAAAAGGCGATACACAAGGG | TPTE2 | ENSG00000132958 | -3.2612679565689 | [] | [] | -4 | hSpCas9 | negative selection | 3571988 | 19451168 | 19451191 | 13 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ATAGATTGTAGACTCGATAGTGG | TPTE2 | ENSG00000132958 | -14.9973151131378 | [] | [] | -9 | hSpCas9 | negative selection | 3571989 | 19492852 | 19492875 | 13 | + | 26780180 | A375 | viability (Avana lentiGuide) | TTTACTGATAGGTGACACCAGGG | TPTE2 | ENSG00000132958 | -0.762444273471206 | [] | [] | -1 | hSpCas9 | negative selection | 3680643 | 19493467 | 19493490 | 13 | - | 26780180 | A375 | viability (Avana lentiGuide) | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 5.81312710445278 | [] | [] | 5 | hSpCas9 | negative selection | 3680644 | 19465464 | 19465487 | 13 | - | 26780180 | A375 | viability (Avana lentiGuide) | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 3.38632477346173 | [] | [] | 3 | hSpCas9 | negative selection | 3680645 | 19464483 | 19464506 | 13 | - | 26780180 | A375 | viability (Avana lentiGuide) | TGTCATTTCCATCTTCTGGAAGG | TPTE2 | ENSG00000132958 | 5.93267008557092 | [] | [] | 5 | hSpCas9 | negative selection | 3680646 | 19465288 | 19465311 | 13 | - | 26780180 | A375 | viability (Avana lentiGuide) | AAACAAAAGGCGATACACAAGGG | TPTE2 | ENSG00000132958 | 19.6678627389932 | [] | [] | 8 | hSpCas9 | negative selection | 3680647 | 19451168 | 19451191 | 13 | + | 26780180 | A375 | viability (Avana lentiGuide) | ATAGATTGTAGACTCGATAGTGG | TPTE2 | ENSG00000132958 | 17.5463437645368 | [] | [] | 8 | hSpCas9 | negative selection | 3680648 | 19492852 | 19492875 | 13 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TTTACTGATAGGTGACACCAGGG | TPTE2 | ENSG00000132958 | -0.29127649776196896 | [6] | [5,4] | -4 | hSpCas9 | positive selection | 3789250 | 19493467 | 19493490 | 13 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | -1.3588064545175262 | [5] | [2,0] | -9 | hSpCas9 | positive selection | 3789251 | 19465464 | 19465487 | 13 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.16755636737409613 | [6] | [6,6] | 4 | hSpCas9 | positive selection | 3789252 | 19464483 | 19464506 | 13 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TGTCATTTCCATCTTCTGGAAGG | TPTE2 | ENSG00000132958 | -0.7403138419746922 | [7] | [5,2] | -8 | hSpCas9 | positive selection | 3789253 | 19465288 | 19465311 | 13 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AAACAAAAGGCGATACACAAGGG | TPTE2 | ENSG00000132958 | -1.6588283464169968 | [5] | [1,0] | -9 | hSpCas9 | positive selection | 3789254 | 19451168 | 19451191 | 13 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ATAGATTGTAGACTCGATAGTGG | TPTE2 | ENSG00000132958 | -0.8232565624975267 | [8] | [4,3] | -8 | hSpCas9 | positive selection | 3789255 | 19492852 | 19492875 | 13 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TTTACTGATAGGTGACACCAGGG | TPTE2 | ENSG00000132958 | -0.10200404951550508 | [5] | [4,4] | -1 | hSpCas9 | positive selection | 3897857 | 19493467 | 19493490 | 13 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | -0.4772800276880338 | [5] | [2,3] | -6 | hSpCas9 | positive selection | 3897858 | 19465464 | 19465487 | 13 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | -0.05290700411290977 | [7] | [5,5] | 0 | hSpCas9 | positive selection | 3897859 | 19464483 | 19464506 | 13 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TGTCATTTCCATCTTCTGGAAGG | TPTE2 | ENSG00000132958 | 0.001249438597163366 | [7] | [5,6] | 0 | hSpCas9 | positive selection | 3897860 | 19465288 | 19465311 | 13 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AAACAAAAGGCGATACACAAGGG | TPTE2 | ENSG00000132958 | -1.012987523583507 | [4] | [1,1] | -8 | hSpCas9 | positive selection | 3897861 | 19451168 | 19451191 | 13 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ATAGATTGTAGACTCGATAGTGG | TPTE2 | ENSG00000132958 | -0.6665241149375667 | [7] | [4,2] | -7 | hSpCas9 | positive selection | 3897862 | 19493439 | 19493462 | 13 | + | 26780180 | A375 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 1.09787734683847 | [] | [] | 5 | hSpCas9 | negative selection | 4007182 | 19493439 | 19493462 | 13 | + | 26780180 | HT29 | viability (GeCKOv2 library) | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 1.69895156692555 | [] | [] | 8 | hSpCas9 | negative selection | 4115148 | 19493439 | 19493462 | 13 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.013088050957304781 | [3] | [2,1] | 0 | hSpCas9 | positive selection | 4304837 | 19464443 | 19464465 | 13 | + | 27760321 | OCIAML3 | viability | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | 1.3874134779583676 | [29,20] | [38,67] | 9 | hSpCas9 | negative selection | 4449600 | 19492852 | 19492874 | 13 | + | 27760321 | OCIAML3 | viability | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | 0.35470358927996104 | [138,119] | [116,144] | 4 | hSpCas9 | negative selection | 4449601 | 19438107 | 19438129 | 13 | + | 27760321 | OCIAML3 | viability | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.3290361782490432 | [135,115] | [62,97] | -3 | hSpCas9 | negative selection | 4449602 | 19467265 | 19467287 | 13 | + | 27760321 | OCIAML3 | viability | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | -0.09715305652164398 | [422,423] | [334,278] | -1 | hSpCas9 | negative selection | 4449603 | 19464443 | 19464465 | 13 | + | 27760321 | OCIAML2 | viability | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | 0.1411353794708501 | [29,20] | [12,34] | 1 | hSpCas9 | negative selection | 4533063 | 19492852 | 19492874 | 13 | + | 27760321 | OCIAML2 | viability | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | 0.373935179533452 | [138,119] | [99,181] | 5 | hSpCas9 | negative selection | 4533064 | 19438107 | 19438129 | 13 | + | 27760321 | OCIAML2 | viability | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -1.036976827774539 | [135,115] | [36,65] | -7 | hSpCas9 | negative selection | 4533065 | 19467265 | 19467287 | 13 | + | 27760321 | OCIAML2 | viability | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | 0.8075611422289968 | [422,423] | [526,699] | 9 | hSpCas9 | negative selection | 4533066 | 19464443 | 19464465 | 13 | + | 27760321 | MV411 | viability | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | 1.9307010107738192 | [29,20] | [104,0] | 9 | hSpCas9 | negative selection | 4616526 | 19492852 | 19492874 | 13 | + | 27760321 | MV411 | viability | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | 0.8290753528788635 | [138,119] | [154,145] | 6 | hSpCas9 | negative selection | 4616527 | 19438107 | 19438129 | 13 | + | 27760321 | MV411 | viability | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.9664438874952344 | [135,115] | [59,15] | -6 | hSpCas9 | negative selection | 4616528 | 19467265 | 19467287 | 13 | + | 27760321 | MV411 | viability | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | 0.40610238686261785 | [422,423] | [341,415] | 3 | hSpCas9 | negative selection | 4616529 | 19464443 | 19464465 | 13 | + | 27760321 | HL60 | viability | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | -0.08563348063026321 | [29,20] | [32,4] | -1 | hSpCas9 | negative selection | 4699989 | 19492852 | 19492874 | 13 | + | 27760321 | HL60 | viability | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | 0.08674137910887203 | [138,119] | [79,145] | 1 | hSpCas9 | negative selection | 4699990 | 19438107 | 19438129 | 13 | + | 27760321 | HL60 | viability | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | 0.7014548415818531 | [135,115] | [94,242] | 7 | hSpCas9 | negative selection | 4699991 | 19467265 | 19467287 | 13 | + | 27760321 | HL60 | viability | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | 0.7554467769400643 | [422,423] | [452,726] | 8 | hSpCas9 | negative selection | 4699992 | 19464443 | 19464465 | 13 | + | 27760321 | HT1080 | viability | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | -0.8051968342039668 | [20,16] | [0,7] | -3 | hSpCas9 | negative selection | 4783452 | 19492852 | 19492874 | 13 | + | 27760321 | HT1080 | viability | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | 2.6344664413074312 | [119,93] | [448,62] | 9 | hSpCas9 | negative selection | 4783453 | 19438107 | 19438129 | 13 | + | 27760321 | HT1080 | viability | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -1.33566336891744 | [115,90] | [12,19] | -5 | hSpCas9 | negative selection | 4783454 | 19467265 | 19467287 | 13 | + | 27760321 | HT1080 | viability | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | -3.1662240444337733 | [423,330] | [0,33] | -7 | hSpCas9 | negative selection | 4783455 | 19464443 | 19464465 | 13 | + | 27760321 | HT29 | viability after 7 days | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | 1.5616150768394856 | [20,16] | [101,79,39] | 9 | hSpCas9 | negative selection | 4866915 | 19492852 | 19492874 | 13 | + | 27760321 | HT29 | viability after 7 days | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | -0.3742904389552191 | [119,93] | [172,116,39] | -5 | hSpCas9 | negative selection | 4866916 | 19438107 | 19438129 | 13 | + | 27760321 | HT29 | viability after 7 days | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.6787238940845741 | [115,90] | [225,32,12] | -7 | hSpCas9 | negative selection | 4866917 | 19467265 | 19467287 | 13 | + | 27760321 | HT29 | viability after 7 days | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | 0.3519904462597246 | [423,330] | [666,535,659] | 5 | hSpCas9 | negative selection | 4866918 | 19464443 | 19464465 | 13 | + | 27760321 | HT29 | viability after 25 days | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | 0.20059656332577536 | [20,16] | [10,55,6] | 2 | hSpCas9 | negative selection | 4950378 | 19492852 | 19492874 | 13 | + | 27760321 | HT29 | viability after 25 days | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | -0.24090926754027842 | [119,93] | [98,147,58] | -3 | hSpCas9 | negative selection | 4950379 | 19438107 | 19438129 | 13 | + | 27760321 | HT29 | viability after 25 days | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -2.5067004614345065 | [115,90] | [18,35,5] | -8 | hSpCas9 | negative selection | 4950380 | 19467265 | 19467287 | 13 | + | 27760321 | HT29 | viability after 25 days | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | 0.5336197385693935 | [423,330] | [461,518,933] | 6 | hSpCas9 | negative selection | 4950381 | 19464443 | 19464465 | 13 | + | 27760321 | HT29 | viability after 22 days | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | 0.9204774106587803 | [20,16] | [43,32,47] | 9 | hSpCas9 | negative selection | 5033841 | 19492852 | 19492874 | 13 | + | 27760321 | HT29 | viability after 22 days | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | -1.8152465679399725 | [119,93] | [11,68,24] | -8 | hSpCas9 | negative selection | 5033842 | 19438107 | 19438129 | 13 | + | 27760321 | HT29 | viability after 22 days | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -2.1353958844884695 | [115,90] | [10,60,9] | -8 | hSpCas9 | negative selection | 5033843 | 19467265 | 19467287 | 13 | + | 27760321 | HT29 | viability after 22 days | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | -0.08706830221290152 | [423,330] | [309,438,486] | -1 | hSpCas9 | negative selection | 5033844 | 19464443 | 19464465 | 13 | + | 27760321 | HT29 | viability after 19 days | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | -1.0534037803195506 | [20,16] | [11,18,0] | -6 | hSpCas9 | negative selection | 5117304 | 19492852 | 19492874 | 13 | + | 27760321 | HT29 | viability after 19 days | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | 0.04843206783806342 | [119,93] | [154,110,116] | 0 | hSpCas9 | negative selection | 5117305 | 19438107 | 19438129 | 13 | + | 27760321 | HT29 | viability after 19 days | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.3448501039142404 | [115,90] | [52,224,0] | -3 | hSpCas9 | negative selection | 5117306 | 19467265 | 19467287 | 13 | + | 27760321 | HT29 | viability after 19 days | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | 0.5807038154842559 | [423,330] | [731,655,560] | 6 | hSpCas9 | negative selection | 5117307 | 19464443 | 19464465 | 13 | + | 27760321 | HT29 | viability after 16 days | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | 2.007947296672679 | [20,16] | [92,37,127] | 9 | hSpCas9 | negative selection | 5200767 | 19492852 | 19492874 | 13 | + | 27760321 | HT29 | viability after 16 days | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | -0.7481459538672413 | [119,93] | [86,45,82] | -6 | hSpCas9 | negative selection | 5200768 | 19438107 | 19438129 | 13 | + | 27760321 | HT29 | viability after 16 days | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -3.06623419007502 | [115,90] | [37,4,0] | -9 | hSpCas9 | negative selection | 5200769 | 19467265 | 19467287 | 13 | + | 27760321 | HT29 | viability after 16 days | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | 0.5322284935081041 | [423,330] | [543,762,514] | 6 | hSpCas9 | negative selection | 5200770 | 19464443 | 19464465 | 13 | + | 27760321 | HT29 | viability after 13 days | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | 0.574103023175804 | [20,16] | [20,15,59] | 7 | hSpCas9 | negative selection | 5284230 | 19492852 | 19492874 | 13 | + | 27760321 | HT29 | viability after 13 days | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | -0.8675788201117736 | [119,93] | [44,87,70] | -7 | hSpCas9 | negative selection | 5284231 | 19438107 | 19438129 | 13 | + | 27760321 | HT29 | viability after 13 days | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -3.3193766622075622 | [115,90] | [0,3,29] | -9 | hSpCas9 | negative selection | 5284232 | 19467265 | 19467287 | 13 | + | 27760321 | HT29 | viability after 13 days | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | 0.24494048639568505 | [423,330] | [565,458,530] | 3 | hSpCas9 | negative selection | 5284233 | 19464443 | 19464465 | 13 | + | 27760321 | HT29 | viability after 10 days | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | 1.277484790270416 | [20,16] | [0,124,48] | 9 | hSpCas9 | negative selection | 5367693 | 19492852 | 19492874 | 13 | + | 27760321 | HT29 | viability after 10 days | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | -0.5811669908752206 | [119,93] | [36,153,78] | -6 | hSpCas9 | negative selection | 5367694 | 19438107 | 19438129 | 13 | + | 27760321 | HT29 | viability after 10 days | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -1.3359126088402484 | [115,90] | [41,42,67] | -8 | hSpCas9 | negative selection | 5367695 | 19467265 | 19467287 | 13 | + | 27760321 | HT29 | viability after 10 days | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | 0.11364137481549605 | [423,330] | [627,500,402] | 1 | hSpCas9 | negative selection | 5367696 | 19464443 | 19464465 | 13 | + | 27760321 | MOLM13 | viability | TAAAGACCCTTACCTCAATTGG | TPTE2 | ENSG00000132958 | 1.7543435993562109 | [29,20] | [0,87] | 9 | hSpCas9 | negative selection | 5451156 | 19492852 | 19492874 | 13 | + | 27760321 | MOLM13 | viability | TTTACTGATAGGTGACACCAGG | TPTE2 | ENSG00000132958 | 0.21081034176396973 | [138,119] | [126,47] | 1 | hSpCas9 | negative selection | 5451157 | 19438107 | 19438129 | 13 | + | 27760321 | MOLM13 | viability | TATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -1.8693690954435007 | [135,115] | [40,0] | -7 | hSpCas9 | negative selection | 5451158 | 19467265 | 19467287 | 13 | + | 27760321 | MOLM13 | viability | AAATGACATCAACCAGCAGAGG | TPTE2 | ENSG00000132958 | 0.7413330106422159 | [422,423] | [517,300] | 5 | hSpCas9 | negative selection | 5451159 | 19502914 | 19502937 | 13 | - | 27661255 | K562 | viability | GAAAAGGAGCAGGTCACAGGAGG | TPTE2 | ENSG00000132958 | -0.01619508151032001 | [1723,1933] | [1553,1345] | 0 | dCas9-KRAB | negative selection | 5519390 | 19503029 | 19503052 | 13 | - | 27661255 | K562 | viability | GACAGATGGACGGACATTTGTGG | TPTE2 | ENSG00000132958 | -0.06616423924143566 | [1185,1354] | [1060,886] | -3 | dCas9-KRAB | negative selection | 5519391 | 19503053 | 19503076 | 13 | - | 27661255 | K562 | viability | GCACACAGTGGAAACATACAAGG | TPTE2 | ENSG00000132958 | 0.004776531802643508 | [789,923] | [638,723] | 0 | dCas9-KRAB | negative selection | 5519392 | 19536439 | 19536462 | 13 | - | 27661255 | K562 | viability | GATTGAGGAGGGACACACAGGGG | TPTE2 | ENSG00000132958 | 0.14182705473299095 | [1558,1661] | [1495,1350] | 5 | dCas9-KRAB | negative selection | 5519393 | 19536696 | 19536719 | 13 | - | 27661255 | K562 | viability | GGAGAACTGATAATAAATTGTGG | TPTE2 | ENSG00000132958 | 0.053172433974955635 | [1289,1469] | [1241,1054] | 1 | dCas9-KRAB | negative selection | 5519394 | 19536717 | 19536740 | 13 | - | 27661255 | K562 | viability | GGGAGAACGTGCCCAAGACCTGG | TPTE2 | ENSG00000132958 | -0.108683087103175 | [774,744] | [658,481] | -4 | dCas9-KRAB | negative selection | 5519395 | 19493439 | 19493462 | 13 | + | 27260156 | BXPC3 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.4648977887587818 | [586] | [722,834,914,935] | 8 | hSpCas9 | negative selection | 5577297 | 19493439 | 19493462 | 13 | + | 27260156 | A673 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.6018427123012595 | [586] | [1310,1027,855,1114] | 9 | hSpCas9 | negative selection | 5698548 | 19493439 | 19493462 | 13 | + | 27260156 | A375 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.7453579121868277 | [586] | [1511,1191,1103,831] | 9 | hSpCas9 | negative selection | 5819799 | 19493439 | 19493462 | 13 | + | 27260156 | COLO741 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.5892949108278054 | [586] | [1190,1167,1035] | 9 | hSpCas9 | negative selection | 5941050 | 19493439 | 19493462 | 13 | + | 27260156 | CAL120 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 1.0319227948068845 | [586] | [1916,1363,1266] | 9 | hSpCas9 | negative selection | 6062301 | 19493439 | 19493462 | 13 | + | 27260156 | CADOES1 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.7759702567470472 | [586] | [943,803,980,1012] | 9 | hSpCas9 | negative selection | 6183552 | 19493439 | 19493462 | 13 | + | 27260156 | EWS502 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.6651240939361405 | [586] | [906,848,1040,1171] | 9 | hSpCas9 | negative selection | 6304803 | 19493439 | 19493462 | 13 | + | 27260156 | EW8 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.7171870264152009 | [586] | [1045,682,697,741] | 9 | hSpCas9 | negative selection | 6426054 | 19493439 | 19493462 | 13 | + | 27260156 | CORL105 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.5368219193329344 | [586] | [1068,756,1440,797] | 8 | hSpCas9 | negative selection | 6547305 | 19493439 | 19493462 | 13 | + | 27260156 | HS294T | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.6097470016442474 | [586] | [249,405,336,408] | 7 | hSpCas9 | negative selection | 6668556 | 19493439 | 19493462 | 13 | + | 27260156 | HCC44 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.8183093342700709 | [586] | [1245,1079,1245,1134] | 9 | hSpCas9 | negative selection | 6789807 | 19493439 | 19493462 | 13 | + | 27260156 | G402 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 1.1038359832753601 | [586] | [1758,1125,1620,1647] | 9 | hSpCas9 | negative selection | 6911058 | 19493439 | 19493462 | 13 | + | 27260156 | L33 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.38976945299705773 | [586] | [786,300,439,852] | 7 | hSpCas9 | negative selection | 7032309 | 19493439 | 19493462 | 13 | + | 27260156 | K562 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.7545858180928151 | [586] | [992,934,801,802] | 8 | hSpCas9 | negative selection | 7153560 | 19493439 | 19493462 | 13 | + | 27260156 | HT29 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.5228599656354391 | [586] | [1206,1034,945,931] | 8 | hSpCas9 | negative selection | 7274811 | 19493439 | 19493462 | 13 | + | 27260156 | MHHES1 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.8428584847459688 | [586] | [1340,1209,1451,821] | 9 | hSpCas9 | negative selection | 7396062 | 19493439 | 19493462 | 13 | + | 27260156 | MEWO | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.5267123158327587 | [586] | [1018,679,718] | 9 | hSpCas9 | negative selection | 7517313 | 19493439 | 19493462 | 13 | + | 27260156 | LNCAPCLONEFGC | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.9836731402598238 | [586] | [962,1176,1113,953] | 9 | hSpCas9 | negative selection | 7638564 | 19493439 | 19493462 | 13 | + | 27260156 | PANC0327 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.4411616402916467 | [586] | [612,700,856,653] | 6 | hSpCas9 | negative selection | 7759815 | 19493439 | 19493462 | 13 | + | 27260156 | NCIH2009 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.6418424881253058 | [586] | [1314,1048,1483] | 8 | hSpCas9 | negative selection | 7881066 | 19493439 | 19493462 | 13 | + | 27260156 | NCIH1373 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 1.028663960537741 | [586] | [1356,806,1192,555] | 9 | hSpCas9 | negative selection | 8002317 | 19493439 | 19493462 | 13 | + | 27260156 | PATU8902 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.6607328565935435 | [586] | [1415,1072,1025,1767] | 7 | hSpCas9 | negative selection | 8123568 | 19493439 | 19493462 | 13 | + | 27260156 | PANC1 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.6260644014956878 | [586] | [652,1003,897,620] | 8 | hSpCas9 | negative selection | 8244819 | 19493439 | 19493462 | 13 | + | 27260156 | PANC0813 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.3571119674458038 | [586] | [805,796,851,1058] | 6 | hSpCas9 | negative selection | 8366070 | 19493439 | 19493462 | 13 | + | 27260156 | RDES | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.9524125571555186 | [586] | [1073,1468,1235,1459] | 9 | hSpCas9 | negative selection | 8487321 | 19493439 | 19493462 | 13 | + | 27260156 | PC3 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.5285116342157392 | [586] | [583,761,1539,787] | 9 | hSpCas9 | negative selection | 8608572 | 19493439 | 19493462 | 13 | + | 27260156 | PATU8988T | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.8148887051044811 | [586] | [879,1074,1080,957] | 9 | hSpCas9 | negative selection | 8729823 | 19493439 | 19493462 | 13 | + | 27260156 | T47D | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.6736650410794958 | [586] | [1078,1050,1011,1229] | 9 | hSpCas9 | negative selection | 8851074 | 19493439 | 19493462 | 13 | + | 27260156 | SU8686 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.5485131030738335 | [586] | [784,740,729,1220] | 8 | hSpCas9 | negative selection | 8972325 | 19493439 | 19493462 | 13 | + | 27260156 | SKES1 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.5645610005194799 | [586] | [929,803,894,830] | 9 | hSpCas9 | negative selection | 9093576 | 19493439 | 19493462 | 13 | + | 27260156 | TOV112D | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.40077072376689454 | [586] | [665,1015,762,709] | 7 | hSpCas9 | negative selection | 9214827 | 19493439 | 19493462 | 13 | + | 27260156 | TC71 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.4205130281965049 | [586] | [837,831,877,817] | 8 | hSpCas9 | negative selection | 9336078 | 19493439 | 19493462 | 13 | + | 27260156 | TC32 | viability | ATTACTTACCTTTCTTTCGCAGG | TPTE2 | ENSG00000132958 | 0.8205486264617323 | [586] | [907,805,1050,1167] | 9 | hSpCas9 | negative selection | 9457329 | 19493467 | 19493490 | 13 | - | 28162770 | P31FUJ | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.2037150222749166 | [149] | [202] | 2 | hSpCas9 | negative selection | 10255978 | 19465249 | 19465272 | 13 | + | 28162770 | P31FUJ | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | -0.01732505115765881 | [477] | [554] | 0 | hSpCas9 | negative selection | 10255979 | 19438125 | 19438148 | 13 | + | 28162770 | P31FUJ | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | 0.0926837098861728 | [161] | [202] | 0 | hSpCas9 | negative selection | 10255980 | 19438106 | 19438129 | 13 | + | 28162770 | P31FUJ | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.5476755417677905 | [50] | [40] | -4 | hSpCas9 | negative selection | 10255981 | 19465464 | 19465487 | 13 | - | 28162770 | P31FUJ | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.8543197756315662 | [248] | [528] | 8 | hSpCas9 | negative selection | 10255982 | 19423085 | 19423108 | 13 | - | 28162770 | P31FUJ | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | -0.27836478179482255 | [192] | [186] | -3 | hSpCas9 | negative selection | 10255983 | 19423078 | 19423101 | 13 | + | 28162770 | P31FUJ | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 0.02695706938655429 | [146] | [175] | 0 | hSpCas9 | negative selection | 10255984 | 19474014 | 19474037 | 13 | + | 28162770 | P31FUJ | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.5851094852166412 | [602] | [1062] | 6 | hSpCas9 | negative selection | 10255985 | 19465284 | 19465307 | 13 | - | 28162770 | P31FUJ | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | 0.22858561118824505 | [267] | [368] | 2 | hSpCas9 | negative selection | 10255986 | 19464475 | 19464498 | 13 | + | 28162770 | P31FUJ | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 0.46970391900845443 | [321] | [523] | 5 | hSpCas9 | negative selection | 10255987 | 19493467 | 19493490 | 13 | - | 28162770 | TF1 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | NaN | [NaN] | [176] | 1 | hSpCas9 | negative selection | 10425344 | 19465249 | 19465272 | 13 | + | 28162770 | TF1 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | NaN | [NaN] | [796] | 1 | hSpCas9 | negative selection | 10425345 | 19438125 | 19438148 | 13 | + | 28162770 | TF1 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | NaN | [NaN] | [197] | 1 | hSpCas9 | negative selection | 10425346 | 19438106 | 19438129 | 13 | + | 28162770 | TF1 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | NaN | [NaN] | [8] | 1 | hSpCas9 | negative selection | 10425347 | 19465464 | 19465487 | 13 | - | 28162770 | TF1 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | NaN | [NaN] | [271] | 1 | hSpCas9 | negative selection | 10425348 | 19423085 | 19423108 | 13 | - | 28162770 | TF1 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | NaN | [NaN] | [352] | 1 | hSpCas9 | negative selection | 10425349 | 19423078 | 19423101 | 13 | + | 28162770 | TF1 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | NaN | [NaN] | [205] | 1 | hSpCas9 | negative selection | 10425350 | 19474014 | 19474037 | 13 | + | 28162770 | TF1 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | NaN | [NaN] | [620] | 1 | hSpCas9 | negative selection | 10425351 | 19465284 | 19465307 | 13 | - | 28162770 | TF1 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | NaN | [NaN] | [176] | 1 | hSpCas9 | negative selection | 10425352 | 19464475 | 19464498 | 13 | + | 28162770 | TF1 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | NaN | [NaN] | [486] | 1 | hSpCas9 | negative selection | 10425353 | 19493467 | 19493490 | 13 | - | 28162770 | SKM1 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.6436618743268063 | [41] | [115] | 6 | hSpCas9 | negative selection | 10594710 | 19465249 | 19465272 | 13 | + | 28162770 | SKM1 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | 0.1779983019779945 | [140] | [281] | 1 | hSpCas9 | negative selection | 10594711 | 19438125 | 19438148 | 13 | + | 28162770 | SKM1 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | 0.3974434392641056 | [69] | [162] | 4 | hSpCas9 | negative selection | 10594712 | 19438106 | 19438129 | 13 | + | 28162770 | SKM1 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.48096478018693856 | [14] | [18] | -4 | hSpCas9 | negative selection | 10594713 | 19465464 | 19465487 | 13 | - | 28162770 | SKM1 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.8694117443297931 | [73] | [238] | 8 | hSpCas9 | negative selection | 10594714 | 19423085 | 19423108 | 13 | - | 28162770 | SKM1 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.5366849468754745 | [61] | [158] | 5 | hSpCas9 | negative selection | 10594715 | 19423078 | 19423101 | 13 | + | 28162770 | SKM1 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 1.5626621522133193 | [17] | [93] | 9 | hSpCas9 | negative selection | 10594716 | 19474014 | 19474037 | 13 | + | 28162770 | SKM1 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.19405815287409367 | [133] | [270] | 2 | hSpCas9 | negative selection | 10594717 | 19465284 | 19465307 | 13 | - | 28162770 | SKM1 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | -0.384937892413163 | [64] | [87] | -3 | hSpCas9 | negative selection | 10594718 | 19464475 | 19464498 | 13 | + | 28162770 | SKM1 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 0.8376581699767518 | [68] | [217] | 7 | hSpCas9 | negative selection | 10594719 | 19493467 | 19493490 | 13 | - | 28162770 | SKM1 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.6436618743268063 | [41] | [115] | 6 | hSpCas9 | negative selection | 10764076 | 19465249 | 19465272 | 13 | + | 28162770 | SKM1 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | 0.1779983019779945 | [140] | [281] | 1 | hSpCas9 | negative selection | 10764077 | 19438125 | 19438148 | 13 | + | 28162770 | SKM1 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | 0.3974434392641056 | [69] | [162] | 4 | hSpCas9 | negative selection | 10764078 | 19438106 | 19438129 | 13 | + | 28162770 | SKM1 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.48096478018693856 | [14] | [18] | -4 | hSpCas9 | negative selection | 10764079 | 19465464 | 19465487 | 13 | - | 28162770 | SKM1 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.8694117443297931 | [73] | [238] | 8 | hSpCas9 | negative selection | 10764080 | 19423085 | 19423108 | 13 | - | 28162770 | SKM1 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.5366849468754745 | [61] | [158] | 5 | hSpCas9 | negative selection | 10764081 | 19423078 | 19423101 | 13 | + | 28162770 | SKM1 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 1.5626621522133193 | [17] | [93] | 9 | hSpCas9 | negative selection | 10764082 | 19474014 | 19474037 | 13 | + | 28162770 | SKM1 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.19405815287409367 | [133] | [270] | 2 | hSpCas9 | negative selection | 10764083 | 19465284 | 19465307 | 13 | - | 28162770 | SKM1 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | -0.384937892413163 | [64] | [87] | -3 | hSpCas9 | negative selection | 10764084 | 19464475 | 19464498 | 13 | + | 28162770 | SKM1 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 0.8376581699767518 | [68] | [217] | 7 | hSpCas9 | negative selection | 10764085 | 19493467 | 19493490 | 13 | - | 28162770 | PL21 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.3002065695932423 | [180] | [96] | 2 | hSpCas9 | negative selection | 10933442 | 19465249 | 19465272 | 13 | + | 28162770 | PL21 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | 0.2637047432667865 | [332] | [173] | 2 | hSpCas9 | negative selection | 10933443 | 19438125 | 19438148 | 13 | + | 28162770 | PL21 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | -0.19154739751214284 | [285] | [108] | -1 | hSpCas9 | negative selection | 10933444 | 19438106 | 19438129 | 13 | + | 28162770 | PL21 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -2.6825034348725216 | [58] | [3] | -9 | hSpCas9 | negative selection | 10933445 | 19465464 | 19465487 | 13 | - | 28162770 | PL21 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 1.214353473709021 | [201] | [203] | 8 | hSpCas9 | negative selection | 10933446 | 19423085 | 19423108 | 13 | - | 28162770 | PL21 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.24487792925460455 | [253] | [130] | 2 | hSpCas9 | negative selection | 10933447 | 19423078 | 19423101 | 13 | + | 28162770 | PL21 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 0.5338770116663158 | [145] | [91] | 4 | hSpCas9 | negative selection | 10933448 | 19474014 | 19474037 | 13 | + | 28162770 | PL21 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 1.0958815306960026 | [458] | [426] | 8 | hSpCas9 | negative selection | 10933449 | 19465284 | 19465307 | 13 | - | 28162770 | PL21 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | -0.35658920550289214 | [252] | [85] | -3 | hSpCas9 | negative selection | 10933450 | 19464475 | 19464498 | 13 | + | 28162770 | PL21 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 0.6834970723720979 | [298] | [208] | 6 | hSpCas9 | negative selection | 10933451 | 19493467 | 19493490 | 13 | - | 28162770 | P31FUJ | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.2037150222749166 | [149] | [202] | 2 | hSpCas9 | negative selection | 11102808 | 19465249 | 19465272 | 13 | + | 28162770 | P31FUJ | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | -0.01732505115765881 | [477] | [554] | 0 | hSpCas9 | negative selection | 11102809 | 19438125 | 19438148 | 13 | + | 28162770 | P31FUJ | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | 0.0926837098861728 | [161] | [202] | 0 | hSpCas9 | negative selection | 11102810 | 19438106 | 19438129 | 13 | + | 28162770 | P31FUJ | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.5476755417677905 | [50] | [40] | -4 | hSpCas9 | negative selection | 11102811 | 19465464 | 19465487 | 13 | - | 28162770 | P31FUJ | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.8543197756315662 | [248] | [528] | 8 | hSpCas9 | negative selection | 11102812 | 19423085 | 19423108 | 13 | - | 28162770 | P31FUJ | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | -0.27836478179482255 | [192] | [186] | -3 | hSpCas9 | negative selection | 11102813 | 19423078 | 19423101 | 13 | + | 28162770 | P31FUJ | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 0.02695706938655429 | [146] | [175] | 0 | hSpCas9 | negative selection | 11102814 | 19474014 | 19474037 | 13 | + | 28162770 | P31FUJ | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.5851094852166412 | [602] | [1062] | 6 | hSpCas9 | negative selection | 11102815 | 19465284 | 19465307 | 13 | - | 28162770 | P31FUJ | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | 0.22858561118824505 | [267] | [368] | 2 | hSpCas9 | negative selection | 11102816 | 19464475 | 19464498 | 13 | + | 28162770 | P31FUJ | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 0.46970391900845443 | [321] | [523] | 5 | hSpCas9 | negative selection | 11102817 | 19493467 | 19493490 | 13 | - | 28162770 | OCIAML5 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.7239628050871515 | [53] | [160] | 6 | hSpCas9 | negative selection | 11272174 | 19465249 | 19465272 | 13 | + | 28162770 | OCIAML5 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | 0.42055388379899483 | [249] | [603] | 3 | hSpCas9 | negative selection | 11272175 | 19438125 | 19438148 | 13 | + | 28162770 | OCIAML5 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | 0.7745651091582326 | [90] | [280] | 6 | hSpCas9 | negative selection | 11272176 | 19438106 | 19438129 | 13 | + | 28162770 | OCIAML5 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | 1.8324316034080734 | [6] | [44] | 9 | hSpCas9 | negative selection | 11272177 | 19465464 | 19465487 | 13 | - | 28162770 | OCIAML5 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.626696526025234 | [154] | [431] | 5 | hSpCas9 | negative selection | 11272178 | 19423085 | 19423108 | 13 | - | 28162770 | OCIAML5 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.43384230122238343 | [145] | [355] | 4 | hSpCas9 | negative selection | 11272179 | 19423078 | 19423101 | 13 | + | 28162770 | OCIAML5 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 0.914342801194691 | [96] | [329] | 7 | hSpCas9 | negative selection | 11272180 | 19474014 | 19474037 | 13 | + | 28162770 | OCIAML5 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.5562135622395381 | [320] | [851] | 5 | hSpCas9 | negative selection | 11272181 | 19465284 | 19465307 | 13 | - | 28162770 | OCIAML5 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | 0.38946001742916614 | [213] | [505] | 3 | hSpCas9 | negative selection | 11272182 | 19464475 | 19464498 | 13 | + | 28162770 | OCIAML5 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 1.284978299236903 | [142] | [628] | 9 | hSpCas9 | negative selection | 11272183 | 19493467 | 19493490 | 13 | - | 28162770 | EOL1 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 1.5165306999694632 | [204] | [308] | 9 | hSpCas9 | negative selection | 11441540 | 19465249 | 19465272 | 13 | + | 28162770 | EOL1 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | 0.21281421415043378 | [528] | [322] | 2 | hSpCas9 | negative selection | 11441541 | 19438125 | 19438148 | 13 | + | 28162770 | EOL1 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | -0.1778139460591433 | [437] | [203] | -1 | hSpCas9 | negative selection | 11441542 | 19438106 | 19438129 | 13 | + | 28162770 | EOL1 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.8985744663453861 | [91] | [25] | -6 | hSpCas9 | negative selection | 11441543 | 19465464 | 19465487 | 13 | - | 28162770 | EOL1 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.7255667368441392 | [488] | [425] | 6 | hSpCas9 | negative selection | 11441544 | 19423085 | 19423108 | 13 | - | 28162770 | EOL1 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 1.0080040026630575 | [402] | [426] | 8 | hSpCas9 | negative selection | 11441545 | 19423078 | 19423101 | 13 | + | 28162770 | EOL1 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | -1.698382579349642 | [153] | [24] | -8 | hSpCas9 | negative selection | 11441546 | 19474014 | 19474037 | 13 | + | 28162770 | EOL1 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | -0.15147009527424304 | [564] | [267] | -1 | hSpCas9 | negative selection | 11441547 | 19465284 | 19465307 | 13 | - | 28162770 | EOL1 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | -0.03429490367270563 | [310] | [159] | 0 | hSpCas9 | negative selection | 11441548 | 19464475 | 19464498 | 13 | + | 28162770 | EOL1 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 1.0760942436979923 | [315] | [350] | 8 | hSpCas9 | negative selection | 11441549 | 19493467 | 19493490 | 13 | - | 28162770 | MOLM13 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.2141327892987957 | [247] | [207] | 1 | hSpCas9 | negative selection | 11610906 | 19465249 | 19465272 | 13 | + | 28162770 | MOLM13 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | -1.2004015027754735 | [587] | [184] | -6 | hSpCas9 | negative selection | 11610907 | 19438125 | 19438148 | 13 | + | 28162770 | MOLM13 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | -0.3133567741823214 | [396] | [230] | -2 | hSpCas9 | negative selection | 11610908 | 19438106 | 19438129 | 13 | + | 28162770 | MOLM13 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | 0.016510035202014883 | [66] | [48] | 0 | hSpCas9 | negative selection | 11610909 | 19465464 | 19465487 | 13 | - | 28162770 | MOLM13 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 1.138825105375588 | [379] | [604] | 8 | hSpCas9 | negative selection | 11610910 | 19423085 | 19423108 | 13 | - | 28162770 | MOLM13 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.8467245152920709 | [342] | [445] | 6 | hSpCas9 | negative selection | 11610911 | 19423078 | 19423101 | 13 | + | 28162770 | MOLM13 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 1.1204763151024957 | [256] | [403] | 8 | hSpCas9 | negative selection | 11610912 | 19474014 | 19474037 | 13 | + | 28162770 | MOLM13 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.3343530367583365 | [689] | [628] | 2 | hSpCas9 | negative selection | 11610913 | 19465284 | 19465307 | 13 | - | 28162770 | MOLM13 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | 0.38135263107658374 | [291] | [274] | 2 | hSpCas9 | negative selection | 11610914 | 19464475 | 19464498 | 13 | + | 28162770 | MOLM13 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | -0.32243943822035226 | [357] | [206] | -2 | hSpCas9 | negative selection | 11610915 | 19493467 | 19493490 | 13 | - | 28162770 | HEL | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.43205983122769953 | [183] | [158] | 3 | hSpCas9 | negative selection | 11780272 | 19465249 | 19465272 | 13 | + | 28162770 | HEL | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | -0.3598168729033996 | [564] | [281] | -3 | hSpCas9 | negative selection | 11780273 | 19438125 | 19438148 | 13 | + | 28162770 | HEL | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | 0.4917969339256174 | [301] | [271] | 4 | hSpCas9 | negative selection | 11780274 | 19438106 | 19438129 | 13 | + | 28162770 | HEL | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.5457062574127534 | [97] | [42] | -4 | hSpCas9 | negative selection | 11780275 | 19465464 | 19465487 | 13 | - | 28162770 | HEL | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 1.0810316835795037 | [399] | [541] | 8 | hSpCas9 | negative selection | 11780276 | 19423085 | 19423108 | 13 | - | 28162770 | HEL | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.28016875261564866 | [314] | [244] | 2 | hSpCas9 | negative selection | 11780277 | 19423078 | 19423101 | 13 | + | 28162770 | HEL | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 0.5512404775148609 | [178] | [167] | 4 | hSpCas9 | negative selection | 11780278 | 19474014 | 19474037 | 13 | + | 28162770 | HEL | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.5948838628555793 | [612] | [592] | 5 | hSpCas9 | negative selection | 11780279 | 19465284 | 19465307 | 13 | - | 28162770 | HEL | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | -0.2728689807092707 | [248] | [131] | -2 | hSpCas9 | negative selection | 11780280 | 19464475 | 19464498 | 13 | + | 28162770 | HEL | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 0.6667442950111464 | [297] | [302] | 6 | hSpCas9 | negative selection | 11780281 | 19493467 | 19493490 | 13 | - | 28162770 | MV411 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.33133880839172036 | [166] | [176] | 3 | hSpCas9 | negative selection | 11949638 | 19465249 | 19465272 | 13 | + | 28162770 | MV411 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | 0.19172811819648783 | [395] | [380] | 1 | hSpCas9 | negative selection | 11949639 | 19438125 | 19438148 | 13 | + | 28162770 | MV411 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | 0.07589427094208018 | [222] | [197] | 0 | hSpCas9 | negative selection | 11949640 | 19438106 | 19438129 | 13 | + | 28162770 | MV411 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -0.8070102332396012 | [53] | [25] | -5 | hSpCas9 | negative selection | 11949641 | 19465464 | 19465487 | 13 | - | 28162770 | MV411 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.6330912432805249 | [247] | [323] | 6 | hSpCas9 | negative selection | 11949642 | 19423085 | 19423108 | 13 | - | 28162770 | MV411 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.14751874217692318 | [268] | [250] | 1 | hSpCas9 | negative selection | 11949643 | 19423078 | 19423101 | 13 | + | 28162770 | MV411 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 0.9325642134293635 | [101] | [163] | 8 | hSpCas9 | negative selection | 11949644 | 19474014 | 19474037 | 13 | + | 28162770 | MV411 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.9441815234798319 | [450] | [730] | 8 | hSpCas9 | negative selection | 11949645 | 19465284 | 19465307 | 13 | - | 28162770 | MV411 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | 1.1543281463912938 | [175] | [329] | 8 | hSpCas9 | negative selection | 11949646 | 19464475 | 19464498 | 13 | + | 28162770 | MV411 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 0.9670932598289004 | [217] | [358] | 8 | hSpCas9 | negative selection | 11949647 | 19493467 | 19493490 | 13 | - | 28162770 | MONOMAC1 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | -0.007559048195840926 | [113] | [129] | 0 | hSpCas9 | negative selection | 12119004 | 19465249 | 19465272 | 13 | + | 28162770 | MONOMAC1 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | 0.6223909072986253 | [254] | [449] | 6 | hSpCas9 | negative selection | 12119005 | 19438125 | 19438148 | 13 | + | 28162770 | MONOMAC1 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | 0.355504175969225 | [134] | [197] | 3 | hSpCas9 | negative selection | 12119006 | 19438106 | 19438129 | 13 | + | 28162770 | MONOMAC1 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | 1.1764215484678906 | [21] | [56] | 8 | hSpCas9 | negative selection | 12119007 | 19465464 | 19465487 | 13 | - | 28162770 | MONOMAC1 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.755878016870705 | [108] | [210] | 7 | hSpCas9 | negative selection | 12119008 | 19423085 | 19423108 | 13 | - | 28162770 | MONOMAC1 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.9701990668551184 | [178] | [401] | 8 | hSpCas9 | negative selection | 12119009 | 19423078 | 19423101 | 13 | + | 28162770 | MONOMAC1 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 0.1373821920110056 | [91] | [115] | 1 | hSpCas9 | negative selection | 12119010 | 19474014 | 19474037 | 13 | + | 28162770 | MONOMAC1 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.24515040038852232 | [328] | [446] | 2 | hSpCas9 | negative selection | 12119011 | 19465284 | 19465307 | 13 | - | 28162770 | MONOMAC1 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | 0.009414030407872698 | [155] | [179] | 0 | hSpCas9 | negative selection | 12119012 | 19464475 | 19464498 | 13 | + | 28162770 | MONOMAC1 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | -0.33938977047088437 | [148] | [134] | -3 | hSpCas9 | negative selection | 12119013 | 19493467 | 19493490 | 13 | - | 28162770 | OCIAML2 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | -0.2583262215292972 | [40] | [189] | -2 | hSpCas9 | negative selection | 12288370 | 19465249 | 19465272 | 13 | + | 28162770 | OCIAML2 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | -0.30482093227208074 | [77] | [349] | -2 | hSpCas9 | negative selection | 12288371 | 19438125 | 19438148 | 13 | + | 28162770 | OCIAML2 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | -0.27236019810588735 | [55] | [256] | -2 | hSpCas9 | negative selection | 12288372 | 19438106 | 19438129 | 13 | + | 28162770 | OCIAML2 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | -1.0720804487518862 | [10] | [28] | -6 | hSpCas9 | negative selection | 12288373 | 19465464 | 19465487 | 13 | - | 28162770 | OCIAML2 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.6518923069693594 | [54] | [478] | 6 | hSpCas9 | negative selection | 12288374 | 19423085 | 19423108 | 13 | - | 28162770 | OCIAML2 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | 0.19922157306550797 | [43] | [279] | 2 | hSpCas9 | negative selection | 12288375 | 19423078 | 19423101 | 13 | + | 28162770 | OCIAML2 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | -0.6703993376179386 | [28] | [100] | -5 | hSpCas9 | negative selection | 12288376 | 19474014 | 19474037 | 13 | + | 28162770 | OCIAML2 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.1450294727019117 | [92] | [569] | 1 | hSpCas9 | negative selection | 12288377 | 19465284 | 19465307 | 13 | - | 28162770 | OCIAML2 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | 0.4314437540685816 | [39] | [298] | 4 | hSpCas9 | negative selection | 12288378 | 19464475 | 19464498 | 13 | + | 28162770 | OCIAML2 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 0.5022583291405975 | [46] | [368] | 5 | hSpCas9 | negative selection | 12288379 | 19493467 | 19493490 | 13 | - | 28162770 | OCIAML3 | viability | CGAATTTAAAGGAACAACCGAGG | TPTE2 | ENSG00000132958 | 0.19125351088282408 | [46] | [161] | 1 | hSpCas9 | negative selection | 12457736 | 19465249 | 19465272 | 13 | + | 28162770 | OCIAML3 | viability | ACAAACCTGTAACGTAAGTGAGG | TPTE2 | ENSG00000132958 | 0.14064779315484177 | [124] | [415] | 1 | hSpCas9 | negative selection | 12457737 | 19438125 | 19438148 | 13 | + | 28162770 | OCIAML3 | viability | GAGGGCACAAACCATAGTCCCGG | TPTE2 | ENSG00000132958 | 0.9780158046894947 | [55] | [332] | 8 | hSpCas9 | negative selection | 12457738 | 19438106 | 19438129 | 13 | + | 28162770 | OCIAML3 | viability | ATATTTCGGAGGCAATAAGGAGG | TPTE2 | ENSG00000132958 | 1.749946760893198 | [12] | [131] | 9 | hSpCas9 | negative selection | 12457739 | 19465464 | 19465487 | 13 | - | 28162770 | OCIAML3 | viability | TGAAAAGCTGATGAGAAGGCTGG | TPTE2 | ENSG00000132958 | 0.9909548603969931 | [78] | [473] | 8 | hSpCas9 | negative selection | 12457740 | 19423085 | 19423108 | 13 | - | 28162770 | OCIAML3 | viability | TTATCCACCAGAATTTGCTGTGG | TPTE2 | ENSG00000132958 | -0.08433326690724406 | [58] | [167] | 0 | hSpCas9 | negative selection | 12457741 | 19423078 | 19423101 | 13 | + | 28162770 | OCIAML3 | viability | AGTATCTCCACAGCAAATTCTGG | TPTE2 | ENSG00000132958 | 0.8310139475273027 | [26] | [144] | 7 | hSpCas9 | negative selection | 12457742 | 19474014 | 19474037 | 13 | + | 28162770 | OCIAML3 | viability | TGAAAATTAGGTCGGCAAGGAGG | TPTE2 | ENSG00000132958 | 0.9020403026026513 | [144] | [817] | 7 | hSpCas9 | negative selection | 12457743 | 19465284 | 19465307 | 13 | - | 28162770 | OCIAML3 | viability | AAAAGGCGATACACAAGGGATGG | TPTE2 | ENSG00000132958 | 0.5936193628516082 | [62] | [286] | 5 | hSpCas9 | negative selection | 12457744 | 19464475 | 19464498 | 13 | + | 28162770 | OCIAML3 | viability | AAAGACTGCCTTCCAGAAGATGG | TPTE2 | ENSG00000132958 | 1.1349206347766245 | [53] | [357] | 8 | hSpCas9 | negative selection | 12457745 |