Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7201
• Symbol:TRHR
• Description:thyrotropin releasing hormone receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/TRHR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
109087548	109087571	8	+	26472758	Jiyoye	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.048915073932286335	[190]	[148]	0	hSpCas9	negative selection	171806
109087653	109087676	8	-	26472758	Jiyoye	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.18690926127781335	[112]	[96]	1	hSpCas9	negative selection	171807
109087569	109087592	8	+	26472758	Jiyoye	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	0.09523137519113323	[71]	[57]	0	hSpCas9	negative selection	171808
109087623	109087646	8	-	26472758	Jiyoye	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.02217359379840711	[438]	[325]	0	hSpCas9	negative selection	171809
109087806	109087829	8	-	26472758	Jiyoye	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	-1.1319834296021578	[92]	[31]	-6	hSpCas9	negative selection	171810
109088029	109088052	8	+	26472758	Jiyoye	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	0.9153222851761986	[134]	[191]	6	hSpCas9	negative selection	171811
109087899	109087922	8	-	26472758	Jiyoye	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	-1.794458479663777	[45]	[9]	-8	hSpCas9	negative selection	171812
109087859	109087882	8	+	26472758	Jiyoye	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.10865189095345462	[320]	[260]	0	hSpCas9	negative selection	171813
109087910	109087933	8	-	26472758	Jiyoye	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	0.6361165886712593	[156]	[183]	4	hSpCas9	negative selection	171814
109088119	109088142	8	-	26472758	Jiyoye	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	-1.6997398224106386	[167]	[38]	-8	hSpCas9	negative selection	171815
109087548	109087571	8	+	26472758	KBM7	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.45605082959021126	[433,420]	[254,295]	5	hSpCas9	negative selection	362924
109087653	109087676	8	-	26472758	KBM7	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.7686531748153219	[688,779]	[557,627]	8	hSpCas9	negative selection	362925
109087569	109087592	8	+	26472758	KBM7	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.838108518872104	[508,285]	[100,102]	-6	hSpCas9	negative selection	362926
109087623	109087646	8	-	26472758	KBM7	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.3416085975108989	[1363,1403]	[936,733]	3	hSpCas9	negative selection	362927
109087806	109087829	8	-	26472758	KBM7	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	0.14250570607654867	[288,144]	[64,148]	1	hSpCas9	negative selection	362928
109088029	109088052	8	+	26472758	KBM7	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	0.2883524153320057	[823,534]	[447,325]	3	hSpCas9	negative selection	362929
109087899	109087922	8	-	26472758	KBM7	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	-0.3963923315119089	[221,154]	[76,56]	-4	hSpCas9	negative selection	362930
109087859	109087882	8	+	26472758	KBM7	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.11292600980426126	[1135,1112]	[621,530]	1	hSpCas9	negative selection	362931
109087910	109087933	8	-	26472758	KBM7	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	-0.264277686265886	[853,839]	[324,339]	-3	hSpCas9	negative selection	362932
109088119	109088142	8	-	26472758	KBM7	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	0.39420305349418633	[222,285]	[187,134]	4	hSpCas9	negative selection	362933
109087548	109087571	8	+	26472758	Raji	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.8958794301798879	[131]	[56]	7	hSpCas9	negative selection	554042
109087653	109087676	8	-	26472758	Raji	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.25736746118199716	[428]	[118]	2	hSpCas9	negative selection	554043
109087569	109087592	8	+	26472758	Raji	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	0.8883737534318038	[141]	[60]	7	hSpCas9	negative selection	554044
109087623	109087646	8	-	26472758	Raji	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.6425930008976559	[471]	[170]	6	hSpCas9	negative selection	554045
109087806	109087829	8	-	26472758	Raji	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	0.4356162071151707	[136]	[42]	4	hSpCas9	negative selection	554046
109088029	109088052	8	+	26472758	Raji	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	1.051674102787312	[263]	[126]	8	hSpCas9	negative selection	554047
109087899	109087922	8	-	26472758	Raji	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	-0.7995070602349191	[149]	[19]	-6	hSpCas9	negative selection	554048
109087859	109087882	8	+	26472758	Raji	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.02993944994825104	[573]	[135]	0	hSpCas9	negative selection	554049
109087910	109087933	8	-	26472758	Raji	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	-0.23408474590940798	[445]	[87]	-2	hSpCas9	negative selection	554050
109088119	109088142	8	-	26472758	Raji	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	0.2914665998125714	[168]	[47]	2	hSpCas9	negative selection	554051
109087548	109087571	8	+	26472758	K562	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.19583854722138516	[452]	[437]	1	hSpCas9	negative selection	745160
109087653	109087676	8	-	26472758	K562	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	1.3484530941242068	[554]	[1192]	9	hSpCas9	negative selection	745161
109087569	109087592	8	+	26472758	K562	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.8291103077555182	[321]	[152]	-5	hSpCas9	negative selection	745162
109087623	109087646	8	-	26472758	K562	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.31006925978635524	[1030]	[1078]	2	hSpCas9	negative selection	745163
109087806	109087829	8	-	26472758	K562	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	1.184099258392635	[231]	[444]	8	hSpCas9	negative selection	745164
109088029	109088052	8	+	26472758	K562	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	0.8859647567539704	[424]	[662]	7	hSpCas9	negative selection	745165
109087899	109087922	8	-	26472758	K562	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	1.446052588836097	[89]	[206]	9	hSpCas9	negative selection	745166
109087859	109087882	8	+	26472758	K562	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.3967307163146656	[933]	[1037]	3	hSpCas9	negative selection	745167
109087910	109087933	8	-	26472758	K562	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	0.7879307848940996	[611]	[891]	6	hSpCas9	negative selection	745168
109088119	109088142	8	-	26472758	K562	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	1.4354993430941874	[172]	[394]	9	hSpCas9	negative selection	745169
109087584	109087607	8	-	26627737	DLD1	viability	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	1.0150515231173167	[188]	[169,142,55]	8	hSpCas9	negative selection	837893
109087623	109087646	8	-	26627737	DLD1	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.799132136029335	[243]	[92,150,151]	7	hSpCas9	negative selection	837894
109087653	109087676	8	-	26627737	DLD1	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	1.0618579235199803	[318]	[200,140,269]	8	hSpCas9	negative selection	837895
109088045	109088068	8	-	26627737	DLD1	viability	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	-0.26552693419072465	[445]	[99,151,99]	-3	hSpCas9	negative selection	837896
109119188	109119211	8	+	26627737	DLD1	viability	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.6222149278408915	[953]	[607,255,497]	6	hSpCas9	negative selection	837897
109087584	109087607	8	-	26627737	GBM cells	viability after 5 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	0.18068484330106527	[152]	[76,108]	3	hSpCas9	negative selection	920208
109087623	109087646	8	-	26627737	GBM cells	viability after 5 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.5885321199212084	[142]	[32,68]	-7	hSpCas9	negative selection	920209
109087653	109087676	8	-	26627737	GBM cells	viability after 5 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.31177700293019245	[165]	[116,103]	5	hSpCas9	negative selection	920210
109088045	109088068	8	-	26627737	GBM cells	viability after 5 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.1117892329541253	[238]	[143,132]	1	hSpCas9	negative selection	920211
109119188	109119211	8	+	26627737	GBM cells	viability after 5 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.25887745845591237	[553]	[332,377]	4	hSpCas9	negative selection	920212
109087584	109087607	8	-	26627737	GBM cells	viability after 13 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	0.7144383617160146	[152]	[149,124]	8	hSpCas9	negative selection	1002523
109087623	109087646	8	-	26627737	GBM cells	viability after 13 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.09201824459594732	[142]	[74,70]	-1	hSpCas9	negative selection	1002524
109087653	109087676	8	-	26627737	GBM cells	viability after 13 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.23368257236093365	[165]	[122,91]	3	hSpCas9	negative selection	1002525
109088045	109088068	8	-	26627737	GBM cells	viability after 13 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	-0.06593680462692365	[238]	[167,87]	-1	hSpCas9	negative selection	1002526
109119188	109119211	8	+	26627737	GBM cells	viability after 13 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.4739171173551864	[553]	[406,425]	6	hSpCas9	negative selection	1002527
109087584	109087607	8	-	26627737	GBM cells	viability after 21 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	1.0782640130536807	[152]	[186,164]	9	hSpCas9	negative selection	1084838
109087623	109087646	8	-	26627737	GBM cells	viability after 21 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.40353042385083615	[142]	[64,52]	-4	hSpCas9	negative selection	1084839
109087653	109087676	8	-	26627737	GBM cells	viability after 21 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.4662254694256751	[165]	[145,104]	5	hSpCas9	negative selection	1084840
109088045	109088068	8	-	26627737	GBM cells	viability after 21 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	-0.1327021306423866	[238]	[119,116]	-1	hSpCas9	negative selection	1084841
109119188	109119211	8	+	26627737	GBM cells	viability after 21 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.8919620064705498	[553]	[604,515]	8	hSpCas9	negative selection	1084842
109087584	109087607	8	-	26627737	RPE1	viability after 9 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	0.5872868823830262	[411]	[274,88]	4	hSpCas9	negative selection	1167153
109087623	109087646	8	-	26627737	RPE1	viability after 9 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-1.1026616191323149	[347]	[72,21]	-7	hSpCas9	negative selection	1167154
109087653	109087676	8	-	26627737	RPE1	viability after 9 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.7554280319832276	[950]	[461,554]	5	hSpCas9	negative selection	1167155
109088045	109088068	8	-	26627737	RPE1	viability after 9 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	1.938465257322319	[431]	[589,425]	8	hSpCas9	negative selection	1167156
109119188	109119211	8	+	26627737	RPE1	viability after 9 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.18665765213710395	[1807]	[438,908]	1	hSpCas9	negative selection	1167157
109087584	109087607	8	-	26627737	RPE1	viability after 12 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	1.0452101859126472	[411]	[276,176]	6	hSpCas9	negative selection	1249468
109087623	109087646	8	-	26627737	RPE1	viability after 12 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.4222676161331538	[347]	[61,77]	-3	hSpCas9	negative selection	1249469
109087653	109087676	8	-	26627737	RPE1	viability after 12 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.4983223197278449	[950]	[340,381]	3	hSpCas9	negative selection	1249470
109088045	109088068	8	-	26627737	RPE1	viability after 12 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	1.333305324604149	[431]	[358,221]	7	hSpCas9	negative selection	1249471
109119188	109119211	8	+	26627737	RPE1	viability after 12 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.2437089841216855	[1807]	[392,767]	1	hSpCas9	negative selection	1249472
109087584	109087607	8	-	26627737	RPE1	viability after 15 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	0.34653104745015684	[411]	[221,76]	2	hSpCas9	negative selection	1331783
109087623	109087646	8	-	26627737	RPE1	viability after 15 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.7722460247417315	[347]	[77,37]	-5	hSpCas9	negative selection	1331784
109087653	109087676	8	-	26627737	RPE1	viability after 15 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.18873361970929703	[950]	[271,339]	1	hSpCas9	negative selection	1331785
109088045	109088068	8	-	26627737	RPE1	viability after 15 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	1.723965572757447	[431]	[392,413]	8	hSpCas9	negative selection	1331786
109119188	109119211	8	+	26627737	RPE1	viability after 15 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	-0.3703021187020834	[1807]	[273,512]	-2	hSpCas9	negative selection	1331787
109087584	109087607	8	-	26627737	RPE1	viability after 18 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	0.7233814176946912	[411]	[243,118]	4	hSpCas9	negative selection	1414098
109087623	109087646	8	-	26627737	RPE1	viability after 18 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.08235263300945905	[347]	[111,85]	0	hSpCas9	negative selection	1414099
109087653	109087676	8	-	26627737	RPE1	viability after 18 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.1658168318859819	[950]	[255,321]	1	hSpCas9	negative selection	1414100
109088045	109088068	8	-	26627737	RPE1	viability after 18 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	1.394958963029318	[431]	[352,256]	7	hSpCas9	negative selection	1414101
109119188	109119211	8	+	26627737	RPE1	viability after 18 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.06715039493966968	[1807]	[282,754]	0	hSpCas9	negative selection	1414102
109087584	109087607	8	-	26627737	HeLa	viability after 8 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	1.6037571050944903	[94]	[234,84,83]	9	hSpCas9	negative selection	1496413
109087623	109087646	8	-	26627737	HeLa	viability after 8 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-1.4100292808478654	[342]	[64,27,75]	-8	hSpCas9	negative selection	1496414
109087653	109087676	8	-	26627737	HeLa	viability after 8 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	-0.07847461540846412	[629]	[291,278,217]	0	hSpCas9	negative selection	1496415
109088045	109088068	8	-	26627737	HeLa	viability after 8 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	-0.49637505472065174	[473]	[165,130,145]	-5	hSpCas9	negative selection	1496416
109119188	109119211	8	+	26627737	HeLa	viability after 8 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.3411979802427053	[738]	[570,307,380]	3	hSpCas9	negative selection	1496417
109087584	109087607	8	-	26627737	HeLa	viability after 12 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	1.8894319192630773	[94]	[279,81,84]	9	hSpCas9	negative selection	1578728
109087623	109087646	8	-	26627737	HeLa	viability after 12 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.337649603724854	[342]	[43,69,224]	-3	hSpCas9	negative selection	1578729
109087653	109087676	8	-	26627737	HeLa	viability after 12 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.3154679608274048	[629]	[442,195,349]	2	hSpCas9	negative selection	1578730
109088045	109088068	8	-	26627737	HeLa	viability after 12 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	-0.08701329789070525	[473]	[236,106,218]	0	hSpCas9	negative selection	1578731
109119188	109119211	8	+	26627737	HeLa	viability after 12 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	-0.01710844078617413	[738]	[161,238,506]	0	hSpCas9	negative selection	1578732
109087584	109087607	8	-	26627737	HeLa	viability after 15 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	2.0475534929719394	[94]	[132,174,172]	9	hSpCas9	negative selection	1661043
109087623	109087646	8	-	26627737	HeLa	viability after 15 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.6649256354008155	[342]	[29,73,166]	-5	hSpCas9	negative selection	1661044
109087653	109087676	8	-	26627737	HeLa	viability after 15 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.04854396383402104	[629]	[154,366,275]	0	hSpCas9	negative selection	1661045
109088045	109088068	8	-	26627737	HeLa	viability after 15 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.7008263603573051	[473]	[380,149,416]	5	hSpCas9	negative selection	1661046
109119188	109119211	8	+	26627737	HeLa	viability after 15 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.0944651798194841	[738]	[184,342,446]	0	hSpCas9	negative selection	1661047
109087584	109087607	8	-	26627737	HeLa	viability after 18 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	2.078021408811844	[94]	[94,145,172]	9	hSpCas9	negative selection	1743358
109087623	109087646	8	-	26627737	HeLa	viability after 18 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.6494140632752511	[342]	[18,64,166]	-5	hSpCas9	negative selection	1743359
109087653	109087676	8	-	26627737	HeLa	viability after 18 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.11918346744674668	[629]	[112,324,275]	1	hSpCas9	negative selection	1743360
109088045	109088068	8	-	26627737	HeLa	viability after 18 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.6832166869000933	[473]	[249,121,416]	5	hSpCas9	negative selection	1743361
109119188	109119211	8	+	26627737	HeLa	viability after 18 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.10518724239115784	[738]	[131,279,446]	0	hSpCas9	negative selection	1743362
109087584	109087607	8	-	26627737	HCT116	viability after 6 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	-0.7153894589211177	[429]	[84,16]	-4	hSpCas9	negative selection	1825673
109087623	109087646	8	-	26627737	HCT116	viability after 6 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.8116452238189273	[442]	[107,1]	-5	hSpCas9	negative selection	1825674
109087653	109087676	8	-	26627737	HCT116	viability after 6 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.16824707127235472	[843]	[248,93]	0	hSpCas9	negative selection	1825675
109088045	109088068	8	-	26627737	HCT116	viability after 6 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.5125990418101568	[468]	[197,53]	3	hSpCas9	negative selection	1825676
109119188	109119211	8	+	26627737	HCT116	viability after 6 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.6138568504033799	[1322]	[316,318]	3	hSpCas9	negative selection	1825677
109087584	109087607	8	-	26627737	HCT116	viability after 8 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	1.187080402553664	[69]	[70,89,101]	8	hSpCas9	negative selection	1907988
109087623	109087646	8	-	26627737	HCT116	viability after 8 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-1.3337243946765345	[272]	[57,59,60]	-9	hSpCas9	negative selection	1907989
109087653	109087676	8	-	26627737	HCT116	viability after 8 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	-0.44288707428995705	[505]	[247,235,132]	-5	hSpCas9	negative selection	1907990
109088045	109088068	8	-	26627737	HCT116	viability after 8 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	-0.1453711827032359	[201]	[93,123,83]	-2	hSpCas9	negative selection	1907991
109119188	109119211	8	+	26627737	HCT116	viability after 8 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	-0.6322413552345455	[724]	[229,306,235]	-6	hSpCas9	negative selection	1907992
109087584	109087607	8	-	26627737	HCT116	viability after 9 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	0.37413249073061944	[429]	[121,169]	3	hSpCas9	negative selection	1990303
109087623	109087646	8	-	26627737	HCT116	viability after 9 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.8249417775243901	[442]	[149,0]	-5	hSpCas9	negative selection	1990304
109087653	109087676	8	-	26627737	HCT116	viability after 9 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	-1.3326566975269816	[843]	[103,77]	-7	hSpCas9	negative selection	1990305
109088045	109088068	8	-	26627737	HCT116	viability after 9 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.2685725880820641	[468]	[156,145]	2	hSpCas9	negative selection	1990306
109119188	109119211	8	+	26627737	HCT116	viability after 9 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.05237015556008262	[1322]	[553,217]	0	hSpCas9	negative selection	1990307
109087584	109087607	8	-	26627737	HCT116	viability after 12 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	1.8413020345443518	[69]	[167,78,143]	9	hSpCas9	negative selection	2072618
109087623	109087646	8	-	26627737	HCT116	viability after 12 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.8450453213589796	[272]	[108,77,49]	-7	hSpCas9	negative selection	2072619
109087653	109087676	8	-	26627737	HCT116	viability after 12 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	-0.0014612892614498385	[505]	[248,248,299]	0	hSpCas9	negative selection	2072620
109088045	109088068	8	-	26627737	HCT116	viability after 12 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.07867550240638727	[201]	[86,172,79]	0	hSpCas9	negative selection	2072621
109119188	109119211	8	+	26627737	HCT116	viability after 12 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	-0.07995436302472037	[724]	[307,483,296]	-1	hSpCas9	negative selection	2072622
109087584	109087607	8	-	26627737	HCT116	viability after 15 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	1.5261412191682706	[69]	[196,107,52]	9	hSpCas9	negative selection	2154933
109087623	109087646	8	-	26627737	HCT116	viability after 15 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-1.377439814378365	[272]	[104,64,16]	-8	hSpCas9	negative selection	2154934
109087653	109087676	8	-	26627737	HCT116	viability after 15 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	-0.0498784360951795	[505]	[336,230,280]	0	hSpCas9	negative selection	2154935
109088045	109088068	8	-	26627737	HCT116	viability after 15 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	-0.15796569571248642	[201]	[214,52,57]	-2	hSpCas9	negative selection	2154936
109119188	109119211	8	+	26627737	HCT116	viability after 15 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	-0.5247889034726567	[724]	[399,220,260]	-5	hSpCas9	negative selection	2154937
109087584	109087607	8	-	26627737	HCT116	viability after 18 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	1.8517258339813178	[69]	[195,86,83]	9	hSpCas9	negative selection	2237248
109087623	109087646	8	-	26627737	HCT116	viability after 18 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-1.9967081882287743	[272]	[51,9,38]	-9	hSpCas9	negative selection	2237249
109087653	109087676	8	-	26627737	HCT116	viability after 18 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.006194231874454115	[505]	[284,246,202]	0	hSpCas9	negative selection	2237250
109088045	109088068	8	-	26627737	HCT116	viability after 18 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	-0.7781376034876485	[201]	[57,37,76]	-6	hSpCas9	negative selection	2237251
109119188	109119211	8	+	26627737	HCT116	viability after 18 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	-0.6237423599741664	[724]	[167,263,248]	-5	hSpCas9	negative selection	2237252
109087258	109087281	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATTGCATCTCTAGTGTAGAATGG	TRHR	ENSG00000174417	0.007687351326116421	[557,124]	[89,57]	0	dCas9-VP64	positive selection	2432303
109087309	109087332	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCTATTCCCATAGAAAAATGGG	TRHR	ENSG00000174417	0.661593402120302	[335,92]	[116,26]	3	dCas9-VP64	positive selection	2432304
109087226	109087249	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTGACCAGCTCACATTAAGAGG	TRHR	ENSG00000174417	-0.3901457676274888	[127,48]	[11,16]	-2	dCas9-VP64	positive selection	2432305
109092509	109092532	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGCCCCCAGG	TRHR	ENSG00000174417	-1.2513288674205318	[297,436]	[21,46]	-7	dCas9-VP64	positive selection	2446562
109087258	109087281	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATTGCATCTCTAGTGTAGAATGG	TRHR	ENSG00000174417	0.5611287749462004	[82,170]	[32,86]	4	dCas9-VP64	positive selection	2527558
109087309	109087332	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCTATTCCCATAGAAAAATGGG	TRHR	ENSG00000174417	-0.6002182754902301	[79,126]	[22,20]	-6	dCas9-VP64	positive selection	2527559
109087226	109087249	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTGACCAGCTCACATTAAGAGG	TRHR	ENSG00000174417	0.32033095137602674	[152,55]	[48,36]	2	dCas9-VP64	positive selection	2527560
109092509	109092532	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGCCCCCAGG	TRHR	ENSG00000174417	0.4244343490827851	[184,278]	[65,133]	3	dCas9-VP64	positive selection	2541817
109087806	109087829	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	-0.26094880002597215	[3,4]	[3,1]	-4	hSpCas9	positive selection	3029047
109087821	109087844	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATTAATTCCCAAATACTGGAGG	TRHR	ENSG00000174417	0.41615880919835196	[3,3]	[4,4]	8	hSpCas9	positive selection	3029048
109087871	109087894	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATTGCTATGTACCTCTCAATGG	TRHR	ENSG00000174417	0.34880251431103104	[3,3]	[4,4]	7	hSpCas9	positive selection	3029049
109087570	109087593	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.5470106352611467	[3,3]	[2,0]	-7	hSpCas9	positive selection	3029050
109087806	109087829	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	-0.30354880075707147	[3,3]	[2,1]	-4	hSpCas9	positive selection	3096905
109087821	109087844	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATTAATTCCCAAATACTGGAGG	TRHR	ENSG00000174417	-0.14191593284629095	[3,3]	[2,1]	-2	hSpCas9	positive selection	3096906
109087871	109087894	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATTGCTATGTACCTCTCAATGG	TRHR	ENSG00000174417	0.21781000704744494	[3,3]	[3,2]	4	hSpCas9	positive selection	3096907
109087570	109087593	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.659817232418826	[3,3]	[2,0]	-8	hSpCas9	positive selection	3096908
109087710	109087733		-	24336571	A375	resistance to PLX after 7 days	CCATGAGATCAGCTACTGCCAGG	TRHR	ENSG00000174417	-0.22168739957531292	[28,21]	[24,17]	-6	hSpCas9	positive selection	3152508
109119311	109119334		+	24336571	A375	resistance to PLX after 7 days	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.15230837729862917	[10,7]	[10,9]	5	hSpCas9	positive selection	3152509
109087687	109087710		-	24336571	A375	resistance to PLX after 7 days	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.1672655187317696	[14,16]	[15,19]	5	hSpCas9	positive selection	3152510
109119287	109119310		+	24336571	A375	resistance to PLX after 7 days	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.257768791779154	[6,7]	[8,8]	7	hSpCas9	positive selection	3152511
109087710	109087733		-	24336571	A375	resistance to PLX after 14 days	CCATGAGATCAGCTACTGCCAGG	TRHR	ENSG00000174417	0.04157568252412758	[21,30]	[13,10]	0	hSpCas9	positive selection	3210301
109119311	109119334		+	24336571	A375	resistance to PLX after 14 days	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	1.2716438261339331	[8,9]	[10,10]	8	hSpCas9	positive selection	3210302
109087687	109087710		-	24336571	A375	resistance to PLX after 14 days	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	2.017211023042642	[13,10]	[24,24]	9	hSpCas9	positive selection	3210303
109119287	109119310		+	24336571	A375	resistance to PLX after 14 days	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	1.0648538200384088	[8,10]	[9,8]	8	hSpCas9	positive selection	3210304
109087710	109087733		-	24336571	A375	viability after 7 days	CCATGAGATCAGCTACTGCCAGG	TRHR	ENSG00000174417	0.39656803654251427	[19]	[28,21]	6	hSpCas9	negative selection	3268094
109119311	109119334		+	24336571	A375	viability after 7 days	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.18661741164213586	[10]	[10,7]	-3	hSpCas9	negative selection	3268095
109087687	109087710		-	24336571	A375	viability after 7 days	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.33437373702795165	[13]	[14,16]	5	hSpCas9	negative selection	3268096
109119287	109119310		+	24336571	A375	viability after 7 days	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.4254834789862031	[10]	[6,7]	-6	hSpCas9	negative selection	3268097
109087710	109087733		-	24336571	A375	viability after 14 days	CCATGAGATCAGCTACTGCCAGG	TRHR	ENSG00000174417	0.48907452132249973	[19]	[21,30]	6	hSpCas9	negative selection	3325887
109119311	109119334		+	24336571	A375	viability after 14 days	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.10918957370214799	[10]	[8,9]	-1	hSpCas9	negative selection	3325888
109087687	109087710		-	24336571	A375	viability after 14 days	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.02162721426589688	[13]	[13,10]	0	hSpCas9	negative selection	3325889
109119287	109119310		+	24336571	A375	viability after 14 days	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.018019582833856573	[10]	[8,10]	0	hSpCas9	negative selection	3325890
109119311	109119334	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-1.2143490029462096	[354,354]	[0,0]	-7	hSpCas9	positive selection	3398921
109087781	109087804	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	1.5808653562391826	[357,357]	[6,6]	6	hSpCas9	positive selection	3398922
109088139	109088162	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	0.21293209208738176	[131,131]	[0,0]	1	hSpCas9	positive selection	3398923
109087806	109087829	8	-	26780180	HT29	viability (Avana library 4 designs)	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	-0.219721168061413	[]	[]	-4	hSpCas9	negative selection	3467895
109087821	109087844	8	-	26780180	HT29	viability (Avana library 4 designs)	CATTAATTCCCAAATACTGGAGG	TRHR	ENSG00000174417	1.11436149231109	[]	[]	4	hSpCas9	negative selection	3467896
109087871	109087894	8	-	26780180	HT29	viability (Avana library 4 designs)	GATTGCTATGTACCTCTCAATGG	TRHR	ENSG00000174417	-0.314171410471027	[]	[]	-5	hSpCas9	negative selection	3467897
109087569	109087592	8	+	26780180	HT29	viability (Avana library 4 designs)	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	1.03646356397243	[]	[]	4	hSpCas9	negative selection	3467898
109087569	109087592	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	4.5071353017333	[]	[]	7	hSpCas9	negative selection	3572289
109087806	109087829	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	5.13622306928839	[]	[]	8	hSpCas9	negative selection	3572290
109087821	109087844	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATTAATTCCCAAATACTGGAGG	TRHR	ENSG00000174417	-6.25191633720828	[]	[]	-6	hSpCas9	negative selection	3572291
109087871	109087894	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATTGCTATGTACCTCTCAATGG	TRHR	ENSG00000174417	-2.7744374108745	[]	[]	-3	hSpCas9	negative selection	3572292
109088073	109088096	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	-4.25632262080534	[]	[]	-5	hSpCas9	negative selection	3572293
109087623	109087646	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.939642924354425	[]	[]	-1	hSpCas9	negative selection	3572294
109087569	109087592	8	+	26780180	A375	viability (Avana lentiGuide)	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-1.96390414402694	[]	[]	-3	hSpCas9	negative selection	3680948
109087806	109087829	8	-	26780180	A375	viability (Avana lentiGuide)	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	-2.27836573358074	[]	[]	-4	hSpCas9	negative selection	3680949
109087821	109087844	8	-	26780180	A375	viability (Avana lentiGuide)	CATTAATTCCCAAATACTGGAGG	TRHR	ENSG00000174417	3.92999789548396	[]	[]	4	hSpCas9	negative selection	3680950
109087871	109087894	8	-	26780180	A375	viability (Avana lentiGuide)	GATTGCTATGTACCTCTCAATGG	TRHR	ENSG00000174417	-6.13296982078391	[]	[]	-9	hSpCas9	negative selection	3680951
109088073	109088096	8	+	26780180	A375	viability (Avana lentiGuide)	CTACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	-4.87557770526384	[]	[]	-8	hSpCas9	negative selection	3680952
109087623	109087646	8	-	26780180	A375	viability (Avana lentiGuide)	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	2.07470960423459	[]	[]	2	hSpCas9	negative selection	3680953
109087569	109087592	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	0.1571869171019255	[4]	[5,4]	4	hSpCas9	positive selection	3789555
109087806	109087829	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	0.11200069362753795	[5]	[6,4]	3	hSpCas9	positive selection	3789556
109087821	109087844	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTAATTCCCAAATACTGGAGG	TRHR	ENSG00000174417	-0.7498579996544014	[6]	[3,2]	-8	hSpCas9	positive selection	3789557
109087871	109087894	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTGCTATGTACCTCTCAATGG	TRHR	ENSG00000174417	-0.049919073421870394	[5]	[5,5]	-1	hSpCas9	positive selection	3789558
109088073	109088096	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	-0.3870117046386405	[8]	[5,5]	-5	hSpCas9	positive selection	3789559
109087623	109087646	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.16125035433459184	[5]	[5,3]	-3	hSpCas9	positive selection	3789560
109087569	109087592	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	0.21321846954777038	[5]	[4,5]	5	hSpCas9	positive selection	3898162
109087806	109087829	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	-0.10634631098948379	[5]	[2,5]	-1	hSpCas9	positive selection	3898163
109087821	109087844	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTAATTCCCAAATACTGGAGG	TRHR	ENSG00000174417	-0.42278092397769634	[5]	[1,4]	-5	hSpCas9	positive selection	3898164
109087871	109087894	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTGCTATGTACCTCTCAATGG	TRHR	ENSG00000174417	0.41378022842656664	[5]	[6,5]	9	hSpCas9	positive selection	3898165
109088073	109088096	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	0.34297994190025155	[7]	[8,7]	8	hSpCas9	positive selection	3898166
109087623	109087646	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.11343611144417798	[6]	[5,3]	-1	hSpCas9	positive selection	3898167
109087692	109087715	8	+	26780180	A375	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.363366259378381	[]	[]	0	hSpCas9	negative selection	4007504
109119311	109119334	8	+	26780180	A375	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.024759611414725	[]	[]	-1	hSpCas9	negative selection	4007505
109087687	109087710	8	-	26780180	A375	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.363790823020544	[]	[]	0	hSpCas9	negative selection	4007506
109119287	109119310	8	+	26780180	A375	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.990077172824046	[]	[]	4	hSpCas9	negative selection	4007507
109087781	109087804	8	-	26780180	A375	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	1.81960277281589	[]	[]	9	hSpCas9	negative selection	4007508
109088139	109088162	8	-	26780180	A375	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	1.31884053562926	[]	[]	7	hSpCas9	negative selection	4007509
109087692	109087715	8	+	26780180	HT29	viability (GeCKOv2 library)	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	1.17969996487687	[]	[]	6	hSpCas9	negative selection	4115470
109119311	109119334	8	+	26780180	HT29	viability (GeCKOv2 library)	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.153545568566424	[]	[]	-4	hSpCas9	negative selection	4115471
109087687	109087710	8	-	26780180	HT29	viability (GeCKOv2 library)	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.421256430558033	[]	[]	1	hSpCas9	negative selection	4115472
109119287	109119310	8	+	26780180	HT29	viability (GeCKOv2 library)	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.578364226539685	[]	[]	2	hSpCas9	negative selection	4115473
109087781	109087804	8	-	26780180	HT29	viability (GeCKOv2 library)	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	1.68636801630264	[]	[]	8	hSpCas9	negative selection	4115474
109088139	109088162	8	-	26780180	HT29	viability (GeCKOv2 library)	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	1.20431450200203	[]	[]	6	hSpCas9	negative selection	4115475
109087710	109087733	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCATGAGATCAGCTACTGCCAGG	TRHR	ENSG00000174417	0.23615268512220994	[4]	[2,3]	6	hSpCas9	positive selection	4179063
109119311	109119334	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.3203645489953211	[2]	[1,3]	7	hSpCas9	positive selection	4179064
109087687	109087710	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.34580606436986355	[3]	[1,4]	8	hSpCas9	positive selection	4179065
109119287	109119310	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.18238353759328818	[3]	[1,3]	5	hSpCas9	positive selection	4179066
109087710	109087733	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCATGAGATCAGCTACTGCCAGG	TRHR	ENSG00000174417	-0.1484561270198811	[4]	[0,0,4,0]	-2	hSpCas9	positive selection	4243085
109119311	109119334	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.8935351576703935	[3]	[1,2,1,3]	6	hSpCas9	positive selection	4243086
109087687	109087710	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.3091134921024057	[4]	[4,4,2,0]	2	hSpCas9	positive selection	4243087
109119287	109119310	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	1.3677408839872272	[2]	[3,0,0,4]	9	hSpCas9	positive selection	4243088
109087687	109087710	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.7941500994742984	[2]	[3,4]	9	hSpCas9	positive selection	4305005
109087692	109087715	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.1124120925246323	[2]	[2,1]	2	hSpCas9	positive selection	4305006
109119287	109119310	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.3955760940763657	[2]	[2,0]	-7	hSpCas9	positive selection	4305007
109119311	109119334	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.15313270448761845	[4]	[4,2]	3	hSpCas9	positive selection	4369253
109087781	109087804	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.18782597838499185	[4]	[3,2]	-4	hSpCas9	positive selection	4369254
109088139	109088162	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.008535716876905228	[3]	[2,2]	0	hSpCas9	positive selection	4369255
109087606	109087628	8	+	27760321	OCIAML3	viability	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	0.47663965943300435	[514,445]	[511,533]	6	hSpCas9	negative selection	4449872
109087749	109087771	8	-	27760321	OCIAML3	viability	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	-0.3101525353410293	[497,386]	[274,279]	-3	hSpCas9	negative selection	4449873
109087781	109087803	8	-	27760321	OCIAML3	viability	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.07998131597622404	[837,609]	[646,521]	0	hSpCas9	negative selection	4449874
109087865	109087887	8	-	27760321	OCIAML3	viability	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	1.7444744927449962	[64,30]	[135,104]	9	hSpCas9	negative selection	4449875
109088074	109088096	8	+	27760321	OCIAML3	viability	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	-2.9720581626800486	[9,9]	[0,0]	-9	hSpCas9	negative selection	4449876
109087606	109087628	8	+	27760321	OCIAML2	viability	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	0.3608373361959524	[514,445]	[496,498]	5	hSpCas9	negative selection	4533335
109087749	109087771	8	-	27760321	OCIAML2	viability	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	0.12897477785129094	[497,386]	[307,494]	1	hSpCas9	negative selection	4533336
109087781	109087803	8	-	27760321	OCIAML2	viability	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.14855815717136978	[837,609]	[607,688]	2	hSpCas9	negative selection	4533337
109087865	109087887	8	-	27760321	OCIAML2	viability	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	-0.6307422821033191	[64,30]	[23,24]	-6	hSpCas9	negative selection	4533338
109088074	109088096	8	+	27760321	OCIAML2	viability	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	-3.0208035279450973	[9,9]	[0,0]	-9	hSpCas9	negative selection	4533339
109087606	109087628	8	+	27760321	MV411	viability	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	-1.0728273171727252	[514,445]	[81,252]	-6	hSpCas9	negative selection	4616798
109087749	109087771	8	-	27760321	MV411	viability	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	-0.4356342174705786	[497,386]	[197,238]	-3	hSpCas9	negative selection	4616799
109087781	109087803	8	-	27760321	MV411	viability	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	1.0700183557860563	[837,609]	[1215,658]	7	hSpCas9	negative selection	4616800
109087865	109087887	8	-	27760321	MV411	viability	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	0.22916313668929789	[64,30]	[0,88]	1	hSpCas9	negative selection	4616801
109088074	109088096	8	+	27760321	MV411	viability	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	-0.6575019935547672	[9,9]	[0,8]	-4	hSpCas9	negative selection	4616802
109087606	109087628	8	+	27760321	HL60	viability	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	0.7577547754276257	[514,445]	[510,821]	8	hSpCas9	negative selection	4700261
109087749	109087771	8	-	27760321	HL60	viability	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	0.3779846073876779	[497,386]	[447,485]	5	hSpCas9	negative selection	4700262
109087781	109087803	8	-	27760321	HL60	viability	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.06848642663106175	[837,609]	[603,624]	0	hSpCas9	negative selection	4700263
109087865	109087887	8	-	27760321	HL60	viability	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	-0.5631702794225233	[64,30]	[20,30]	-6	hSpCas9	negative selection	4700264
109088074	109088096	8	+	27760321	HL60	viability	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	2.4756620124630166	[9,9]	[64,24]	9	hSpCas9	negative selection	4700265
109087606	109087628	8	+	27760321	HT1080	viability	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	1.6231587169607469	[445,347]	[353,632]	8	hSpCas9	negative selection	4783724
109087749	109087771	8	-	27760321	HT1080	viability	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	0.21535180184216762	[386,301]	[81,243]	1	hSpCas9	negative selection	4783725
109087781	109087803	8	-	27760321	HT1080	viability	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.5374848406210064	[609,475]	[386,233]	3	hSpCas9	negative selection	4783726
109087865	109087887	8	-	27760321	HT1080	viability	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	1.841061579091289	[30,23]	[22,56]	8	hSpCas9	negative selection	4783727
109088074	109088096	8	+	27760321	HT1080	viability	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	-1.8443172389209588	[9,7]	[0,0]	-6	hSpCas9	negative selection	4783728
109087606	109087628	8	+	27760321	HT29	viability after 7 days	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	-0.2653137501687579	[445,347]	[548,439,305]	-4	hSpCas9	negative selection	4867187
109087749	109087771	8	-	27760321	HT29	viability after 7 days	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	-0.12448033438596938	[386,301]	[556,440,246]	-2	hSpCas9	negative selection	4867188
109087781	109087803	8	-	27760321	HT29	viability after 7 days	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.5756219709001009	[609,475]	[1080,984,1058]	8	hSpCas9	negative selection	4867189
109087865	109087887	8	-	27760321	HT29	viability after 7 days	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	0.49981645605245184	[30,23]	[3,111,27]	7	hSpCas9	negative selection	4867190
109088074	109088096	8	+	27760321	HT29	viability after 7 days	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	0.9821099000187674	[9,7]	[0,24,38]	9	hSpCas9	negative selection	4867191
109087606	109087628	8	+	27760321	HT29	viability after 25 days	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	0.8009907003230585	[445,347]	[1083,741,494]	8	hSpCas9	negative selection	4950650
109087749	109087771	8	-	27760321	HT29	viability after 25 days	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	-0.44766848766577366	[386,301]	[315,188,366]	-4	hSpCas9	negative selection	4950651
109087781	109087803	8	-	27760321	HT29	viability after 25 days	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.6214782494459377	[609,475]	[816,739,1355]	7	hSpCas9	negative selection	4950652
109087865	109087887	8	-	27760321	HT29	viability after 25 days	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	0.27362138269827474	[30,23]	[34,6,75]	3	hSpCas9	negative selection	4950653
109088074	109088096	8	+	27760321	HT29	viability after 25 days	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	0.17786017202548088	[9,7]	[8,23,0]	1	hSpCas9	negative selection	4950654
109087606	109087628	8	+	27760321	HT29	viability after 22 days	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	0.6412461602339476	[445,347]	[1110,487,535]	7	hSpCas9	negative selection	5034113
109087749	109087771	8	-	27760321	HT29	viability after 22 days	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	-0.5149716588615666	[386,301]	[258,259,317]	-5	hSpCas9	negative selection	5034114
109087781	109087803	8	-	27760321	HT29	viability after 22 days	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.49968408106548257	[609,475]	[984,679,995]	5	hSpCas9	negative selection	5034115
109087865	109087887	8	-	27760321	HT29	viability after 22 days	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	1.094345762032248	[30,23]	[93,22,85]	9	hSpCas9	negative selection	5034116
109088074	109088096	8	+	27760321	HT29	viability after 22 days	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	1.174060106862865	[9,7]	[0,61,7]	9	hSpCas9	negative selection	5034117
109087606	109087628	8	+	27760321	HT29	viability after 19 days	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	0.4335693853416364	[445,347]	[769,482,602]	4	hSpCas9	negative selection	5117576
109087749	109087771	8	-	27760321	HT29	viability after 19 days	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	-0.06414265000919307	[386,301]	[414,199,513]	0	hSpCas9	negative selection	5117577
109087781	109087803	8	-	27760321	HT29	viability after 19 days	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	1.0809632337030304	[609,475]	[838,784,2230]	9	hSpCas9	negative selection	5117578
109087865	109087887	8	-	27760321	HT29	viability after 19 days	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	1.0040759565800594	[30,23]	[96,14,79]	9	hSpCas9	negative selection	5117579
109088074	109088096	8	+	27760321	HT29	viability after 19 days	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	2.0240329564326895	[9,7]	[9,112,0]	9	hSpCas9	negative selection	5117580
109087606	109087628	8	+	27760321	HT29	viability after 16 days	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	-0.17944562483654192	[445,347]	[382,418,372]	-2	hSpCas9	negative selection	5201039
109087749	109087771	8	-	27760321	HT29	viability after 16 days	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	-0.3582798225914096	[386,301]	[346,389,166]	-4	hSpCas9	negative selection	5201040
109087781	109087803	8	-	27760321	HT29	viability after 16 days	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.649087384260449	[609,475]	[1176,571,1139]	7	hSpCas9	negative selection	5201041
109087865	109087887	8	-	27760321	HT29	viability after 16 days	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	1.5383253304317899	[30,23]	[68,166,27]	9	hSpCas9	negative selection	5201042
109088074	109088096	8	+	27760321	HT29	viability after 16 days	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	0.9459965862649478	[9,7]	[3,50,0]	9	hSpCas9	negative selection	5201043
109087606	109087628	8	+	27760321	HT29	viability after 13 days	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	0.15797683181105154	[445,347]	[467,498,570]	2	hSpCas9	negative selection	5284502
109087749	109087771	8	-	27760321	HT29	viability after 13 days	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	-0.09367639515659985	[386,301]	[623,261,244]	-1	hSpCas9	negative selection	5284503
109087781	109087803	8	-	27760321	HT29	viability after 13 days	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.43031337027921857	[609,475]	[768,918,857]	5	hSpCas9	negative selection	5284504
109087865	109087887	8	-	27760321	HT29	viability after 13 days	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	0.06626883052603105	[30,23]	[3,24,68]	0	hSpCas9	negative selection	5284505
109088074	109088096	8	+	27760321	HT29	viability after 13 days	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	0.5627258115713563	[9,7]	[8,32,4]	7	hSpCas9	negative selection	5284506
109087606	109087628	8	+	27760321	HT29	viability after 10 days	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	0.22659390059587203	[445,347]	[600,353,773]	3	hSpCas9	negative selection	5367965
109087749	109087771	8	-	27760321	HT29	viability after 10 days	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	-0.1870287969119495	[386,301]	[309,479,346]	-2	hSpCas9	negative selection	5367966
109087781	109087803	8	-	27760321	HT29	viability after 10 days	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.4733182067086137	[609,475]	[779,1043,1000]	6	hSpCas9	negative selection	5367967
109087865	109087887	8	-	27760321	HT29	viability after 10 days	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	1.686315685268041	[30,23]	[125,96,107]	9	hSpCas9	negative selection	5367968
109088074	109088096	8	+	27760321	HT29	viability after 10 days	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	-2.770696095727388	[9,7]	[0,2,0]	-9	hSpCas9	negative selection	5367969
109087606	109087628	8	+	27760321	MOLM13	viability	GTACTCATTATTTGTGGCCTGG	TRHR	ENSG00000174417	0.9650899571426726	[514,445]	[502,548]	7	hSpCas9	negative selection	5451428
109087749	109087771	8	-	27760321	MOLM13	viability	ACTGTCTGTTATGTTGGGGAGG	TRHR	ENSG00000174417	-1.9423748228893878	[497,386]	[124,12]	-8	hSpCas9	negative selection	5451429
109087781	109087803	8	-	27760321	MOLM13	viability	CCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.1157575822597402	[837,609]	[722,195]	0	hSpCas9	negative selection	5451430
109087865	109087887	8	-	27760321	MOLM13	viability	ATGTACCTCTCAATGGTAAAGG	TRHR	ENSG00000174417	2.0173584526873425	[64,30]	[142,75]	9	hSpCas9	negative selection	5451431
109088074	109088096	8	+	27760321	MOLM13	viability	TACTCACCTATTTACCTAATGG	TRHR	ENSG00000174417	-2.5009227809377714	[9,9]	[0,0]	-8	hSpCas9	negative selection	5451432
109087687	109087710	8	-	27260156	BXPC3	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.4193351068279681	[458]	[509,580,657,858]	8	hSpCas9	negative selection	5577465
109087692	109087715	8	+	27260156	BXPC3	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.24135167291662596	[266]	[234,289,462,346]	5	hSpCas9	negative selection	5577466
109119287	109119310	8	+	27260156	BXPC3	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.1595667000662284	[356]	[377,404,434,456]	3	hSpCas9	negative selection	5577467
109119311	109119334	8	+	27260156	BXPC3	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.023065609603060144	[1033]	[961,978,1148,1191]	0	hSpCas9	negative selection	5641713
109087781	109087804	8	-	27260156	BXPC3	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.016689274886916294	[1117]	[1294,987,1036,1428]	0	hSpCas9	negative selection	5641714
109088139	109088162	8	-	27260156	BXPC3	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.19727839153058435	[554]	[491,522,510,493]	-4	hSpCas9	negative selection	5641715
109087687	109087710	8	-	27260156	A673	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.6497274139747042	[458]	[950,786,922,803]	9	hSpCas9	negative selection	5698716
109087692	109087715	8	+	27260156	A673	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.29513126950743784	[266]	[501,355,345,381]	7	hSpCas9	negative selection	5698717
109119287	109119310	8	+	27260156	A673	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.013834143209158656	[356]	[512,348,402,445]	0	hSpCas9	negative selection	5698718
109119311	109119334	8	+	27260156	A673	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.05056643349242429	[1033]	[1325,1035,1034,1428]	-1	hSpCas9	negative selection	5762964
109087781	109087804	8	-	27260156	A673	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.05856833357073166	[1117]	[1491,1277,1202,1199]	-1	hSpCas9	negative selection	5762965
109088139	109088162	8	-	27260156	A673	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.18443720829508115	[554]	[672,437,539,714]	-4	hSpCas9	negative selection	5762966
109087687	109087710	8	-	27260156	A375	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.7124002960126292	[458]	[897,985,971,691]	9	hSpCas9	negative selection	5819967
109087692	109087715	8	+	27260156	A375	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.32064129188769913	[266]	[428,400,354,374]	5	hSpCas9	negative selection	5819968
109119287	109119310	8	+	27260156	A375	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.11430934421855438	[356]	[494,215,266,521]	-2	hSpCas9	negative selection	5819969
109119311	109119334	8	+	27260156	A375	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.4041380545886448	[1033]	[1954,1744,1578,1180]	6	hSpCas9	negative selection	5884215
109087781	109087804	8	-	27260156	A375	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.005900457719276053	[1117]	[1438,1088,1632,1076]	0	hSpCas9	negative selection	5884216
109088139	109088162	8	-	27260156	A375	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.5473041756176785	[554]	[466,433,431,438]	-6	hSpCas9	negative selection	5884217
109087687	109087710	8	-	27260156	COLO741	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.48851953016204164	[458]	[970,700,807]	8	hSpCas9	negative selection	5941218
109087692	109087715	8	+	27260156	COLO741	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.09281379103117182	[266]	[439,307,349]	2	hSpCas9	negative selection	5941219
109119287	109119310	8	+	27260156	COLO741	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.2912363748282573	[356]	[491,327,311]	-6	hSpCas9	negative selection	5941220
109119311	109119334	8	+	27260156	COLO741	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.2098980475365495	[1033]	[1656,1414,1519]	4	hSpCas9	negative selection	6005466
109087781	109087804	8	-	27260156	COLO741	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.05448080896426699	[1117]	[1533,1287,1318]	-1	hSpCas9	negative selection	6005467
109088139	109088162	8	-	27260156	COLO741	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.30868528512717697	[554]	[636,530,554]	-6	hSpCas9	negative selection	6005468
109087687	109087710	8	-	27260156	CAL120	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.9815729582539058	[458]	[1646,1122,698]	9	hSpCas9	negative selection	6062469
109087692	109087715	8	+	27260156	CAL120	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.2617187641978803	[266]	[486,479,243]	4	hSpCas9	negative selection	6062470
109119287	109119310	8	+	27260156	CAL120	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.28675329364737145	[356]	[548,611,466]	4	hSpCas9	negative selection	6062471
109119311	109119334	8	+	27260156	CAL120	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.19751859755731815	[1033]	[1775,1383,1313]	3	hSpCas9	negative selection	6126717
109087781	109087804	8	-	27260156	CAL120	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.30677186824668257	[1117]	[1968,699,836]	-4	hSpCas9	negative selection	6126718
109088139	109088162	8	-	27260156	CAL120	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.6928442323570818	[554]	[562,311,426]	-7	hSpCas9	negative selection	6126719
109087687	109087710	8	-	27260156	CADOES1	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.47952738610801454	[458]	[565,677,595,538]	7	hSpCas9	negative selection	6183720
109087692	109087715	8	+	27260156	CADOES1	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.2271798519546684	[266]	[191,249,476,241]	4	hSpCas9	negative selection	6183721
109119287	109119310	8	+	27260156	CADOES1	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.1253049464692894	[356]	[335,271,342,264]	-2	hSpCas9	negative selection	6183722
109119311	109119334	8	+	27260156	CADOES1	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.27226949300608816	[1033]	[784,766,813,819]	-5	hSpCas9	negative selection	6247968
109087781	109087804	8	-	27260156	CADOES1	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.11995520407411298	[1117]	[1052,1115,765,889]	-2	hSpCas9	negative selection	6247969
109088139	109088162	8	-	27260156	CADOES1	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.7920880885563296	[554]	[298,331,198,364]	-8	hSpCas9	negative selection	6247970
109087687	109087710	8	-	27260156	EWS502	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.8409178973873739	[458]	[932,797,749,1001]	9	hSpCas9	negative selection	6304971
109087692	109087715	8	+	27260156	EWS502	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.08471218292742555	[266]	[242,369,278,310]	1	hSpCas9	negative selection	6304972
109119287	109119310	8	+	27260156	EWS502	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.2218721090891024	[356]	[451,555,406,332]	4	hSpCas9	negative selection	6304973
109119311	109119334	8	+	27260156	EWS502	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.010927937369493712	[1033]	[1066,867,1083,1354]	0	hSpCas9	negative selection	6369219
109087781	109087804	8	-	27260156	EWS502	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.20259997981474176	[1117]	[877,873,1011,1398]	-4	hSpCas9	negative selection	6369220
109088139	109088162	8	-	27260156	EWS502	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.5626109567162074	[554]	[366,435,433,352]	-7	hSpCas9	negative selection	6369221
109087687	109087710	8	-	27260156	EW8	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.5937416105778189	[458]	[565,610,523,549]	9	hSpCas9	negative selection	6426222
109087692	109087715	8	+	27260156	EW8	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.6266934062487417	[266]	[338,271,282,449]	9	hSpCas9	negative selection	6426223
109119287	109119310	8	+	27260156	EW8	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.37613103455933733	[356]	[418,305,358,423]	6	hSpCas9	negative selection	6426224
109119311	109119334	8	+	27260156	EW8	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.03661743894377589	[1033]	[1090,697,789,892]	0	hSpCas9	negative selection	6490470
109087781	109087804	8	-	27260156	EW8	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.11338113085836787	[1117]	[1085,880,984,975]	2	hSpCas9	negative selection	6490471
109088139	109088162	8	-	27260156	EW8	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.3788141604016483	[554]	[421,425,266,289]	-6	hSpCas9	negative selection	6490472
109087687	109087710	8	-	27260156	CORL105	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.4174128547402993	[458]	[769,673,873,579]	7	hSpCas9	negative selection	6547473
109087692	109087715	8	+	27260156	CORL105	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.17438979726307657	[266]	[301,234,410,471]	3	hSpCas9	negative selection	6547474
109119287	109119310	8	+	27260156	CORL105	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.08316831100232397	[356]	[420,464,538,359]	1	hSpCas9	negative selection	6547475
109119311	109119334	8	+	27260156	CORL105	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.1605949518578833	[1033]	[1337,1502,1354,1212]	3	hSpCas9	negative selection	6611721
109087781	109087804	8	-	27260156	CORL105	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.018035176459936464	[1117]	[1142,1081,1671,1330]	0	hSpCas9	negative selection	6611722
109088139	109088162	8	-	27260156	CORL105	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.40751812575813623	[554]	[565,439,502,455]	-6	hSpCas9	negative selection	6611723
109087687	109087710	8	-	27260156	HS294T	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.5610280371799243	[458]	[313,204,183,355]	7	hSpCas9	negative selection	6668724
109087692	109087715	8	+	27260156	HS294T	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.684348649411212	[266]	[162,160,175,162]	8	hSpCas9	negative selection	6668725
109119287	109119310	8	+	27260156	HS294T	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.21905691701406801	[356]	[203,86,135,223]	3	hSpCas9	negative selection	6668726
109119311	109119334	8	+	27260156	HS294T	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.07500007675528697	[1033]	[402,498,334,449]	1	hSpCas9	negative selection	6732972
109087781	109087804	8	-	27260156	HS294T	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.00648762792114721	[1117]	[303,412,456,602]	0	hSpCas9	negative selection	6732973
109088139	109088162	8	-	27260156	HS294T	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.5258652862060836	[554]	[141,134,154,167]	-6	hSpCas9	negative selection	6732974
109087687	109087710	8	-	27260156	HCC44	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.6056295207341797	[458]	[572,868,1116,624]	8	hSpCas9	negative selection	6789975
109087692	109087715	8	+	27260156	HCC44	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	-0.28459645271643463	[266]	[277,178,254,289]	-4	hSpCas9	negative selection	6789976
109119287	109119310	8	+	27260156	HCC44	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.02728890722389743	[356]	[328,222,667,425]	0	hSpCas9	negative selection	6789977
109119311	109119334	8	+	27260156	HCC44	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.05132521188248895	[1033]	[1067,1145,1092,1181]	-1	hSpCas9	negative selection	6854223
109087781	109087804	8	-	27260156	HCC44	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.18270384831447228	[1117]	[1343,1003,1215,942]	-3	hSpCas9	negative selection	6854224
109088139	109088162	8	-	27260156	HCC44	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.342162417641592	[554]	[569,242,763,488]	-5	hSpCas9	negative selection	6854225
109087687	109087710	8	-	27260156	G402	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.703207978108899	[458]	[888,1219,562,982]	8	hSpCas9	negative selection	6911226
109087692	109087715	8	+	27260156	G402	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.5958431182079056	[266]	[765,214,198,795]	7	hSpCas9	negative selection	6911227
109119287	109119310	8	+	27260156	G402	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.5206097662053328	[356]	[917,497,847,284]	6	hSpCas9	negative selection	6911228
109119311	109119334	8	+	27260156	G402	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.2580565756257096	[1033]	[1406,1779,1388,1456]	3	hSpCas9	negative selection	6975474
109087781	109087804	8	-	27260156	G402	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.18587769368416573	[1117]	[1251,2295,1227,1430]	2	hSpCas9	negative selection	6975475
109088139	109088162	8	-	27260156	G402	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.42090242405448913	[554]	[770,264,636,378]	-5	hSpCas9	negative selection	6975476
109087687	109087710	8	-	27260156	L33	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.38689251250349	[458]	[623,219,397,605]	7	hSpCas9	negative selection	7032477
109087692	109087715	8	+	27260156	L33	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.038426559126384485	[266]	[351,97,163,242]	0	hSpCas9	negative selection	7032478
109119287	109119310	8	+	27260156	L33	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.03389587149983647	[356]	[388,155,215,347]	0	hSpCas9	negative selection	7032479
109119311	109119334	8	+	27260156	L33	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.2786492886931997	[1033]	[752,362,529,928]	-6	hSpCas9	negative selection	7096725
109087781	109087804	8	-	27260156	L33	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.21727155504394102	[1117]	[887,406,527,1124]	-5	hSpCas9	negative selection	7096726
109088139	109088162	8	-	27260156	L33	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.09744511056829971	[554]	[407,237,335,553]	-2	hSpCas9	negative selection	7096727
109087687	109087710	8	-	27260156	K562	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.3456414861554849	[458]	[625,442,654,366]	4	hSpCas9	negative selection	7153728
109087692	109087715	8	+	27260156	K562	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	-0.0745864750336499	[266]	[187,484,42,196]	-1	hSpCas9	negative selection	7153729
109119287	109119310	8	+	27260156	K562	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.5226800263084155	[356]	[231,935,111,535]	6	hSpCas9	negative selection	7153730
109119311	109119334	8	+	27260156	K562	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.06537105137179311	[1033]	[502,959,941,1347]	0	hSpCas9	negative selection	7217976
109087781	109087804	8	-	27260156	K562	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.1078365568913886	[1117]	[1170,1052,794,711]	-1	hSpCas9	negative selection	7217977
109088139	109088162	8	-	27260156	K562	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.11402144819383131	[554]	[704,392,568,198]	-1	hSpCas9	negative selection	7217978
109087687	109087710	8	-	27260156	HT29	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.7147630899750488	[458]	[1053,938,814,866]	9	hSpCas9	negative selection	7274979
109087692	109087715	8	+	27260156	HT29	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.25502558526800967	[266]	[492,434,317,320]	5	hSpCas9	negative selection	7274980
109119287	109119310	8	+	27260156	HT29	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.14503972701139345	[356]	[504,439,556,419]	3	hSpCas9	negative selection	7274981
109119311	109119334	8	+	27260156	HT29	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.028348002295260022	[1033]	[1432,1272,1427,1026]	0	hSpCas9	negative selection	7339227
109087781	109087804	8	-	27260156	HT29	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.1909024020975274	[1117]	[1081,1326,1344,1023]	-4	hSpCas9	negative selection	7339228
109088139	109088162	8	-	27260156	HT29	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.13323597593322373	[554]	[680,629,657,506]	-3	hSpCas9	negative selection	7339229
109087687	109087710	8	-	27260156	MHHES1	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.6341658775425211	[458]	[1079,812,692,669]	9	hSpCas9	negative selection	7396230
109087692	109087715	8	+	27260156	MHHES1	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.47684216861058426	[266]	[322,392,461,461]	8	hSpCas9	negative selection	7396231
109119287	109119310	8	+	27260156	MHHES1	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.1922358628794268	[356]	[365,369,472,224]	-4	hSpCas9	negative selection	7396232
109119311	109119334	8	+	27260156	MHHES1	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.14534005414618423	[1033]	[1555,1348,1317,1004]	2	hSpCas9	negative selection	7460478
109087781	109087804	8	-	27260156	MHHES1	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.013632120666163372	[1117]	[1420,1403,1415,927]	0	hSpCas9	negative selection	7460479
109088139	109088162	8	-	27260156	MHHES1	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.4632060571493942	[554]	[479,398,534,399]	-7	hSpCas9	negative selection	7460480
109087687	109087710	8	-	27260156	MEWO	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.4186572008751646	[458]	[612,457,658]	8	hSpCas9	negative selection	7517481
109087692	109087715	8	+	27260156	MEWO	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.21455397217374106	[266]	[368,251,263]	5	hSpCas9	negative selection	7517482
109119287	109119310	8	+	27260156	MEWO	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.09558690804708958	[356]	[445,317,323]	2	hSpCas9	negative selection	7517483
109119311	109119334	8	+	27260156	MEWO	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.01695899825795122	[1033]	[1196,886,830]	0	hSpCas9	negative selection	7581729
109087781	109087804	8	-	27260156	MEWO	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.34199293353443894	[1117]	[1039,631,845]	-6	hSpCas9	negative selection	7581730
109088139	109088162	8	-	27260156	MEWO	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.23615443434789993	[554]	[594,291,465]	-5	hSpCas9	negative selection	7581731
109087687	109087710	8	-	27260156	LNCAPCLONEFGC	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.6319791114323486	[458]	[378,635,976,639]	8	hSpCas9	negative selection	7638732
109087692	109087715	8	+	27260156	LNCAPCLONEFGC	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.22941369565201586	[266]	[254,275,363,251]	3	hSpCas9	negative selection	7638733
109119287	109119310	8	+	27260156	LNCAPCLONEFGC	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.07941726781951802	[356]	[381,352,307,316]	1	hSpCas9	negative selection	7638734
109119311	109119334	8	+	27260156	LNCAPCLONEFGC	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.16787154562969397	[1033]	[853,1036,1273,1080]	2	hSpCas9	negative selection	7702980
109087781	109087804	8	-	27260156	LNCAPCLONEFGC	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.09135845679762511	[1117]	[931,900,1208,1306]	1	hSpCas9	negative selection	7702981
109088139	109088162	8	-	27260156	LNCAPCLONEFGC	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.10979280244812162	[554]	[464,283,577,564]	-2	hSpCas9	negative selection	7702982
109087687	109087710	8	-	27260156	PANC0327	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.7704845501365617	[458]	[970,283,915,686]	9	hSpCas9	negative selection	7759983
109087692	109087715	8	+	27260156	PANC0327	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.07966506215822433	[266]	[217,233,276,272]	1	hSpCas9	negative selection	7759984
109119287	109119310	8	+	27260156	PANC0327	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.284689112926128	[356]	[692,247,303,342]	4	hSpCas9	negative selection	7759985
109119311	109119334	8	+	27260156	PANC0327	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.22785270958512926	[1033]	[802,891,1346,1261]	3	hSpCas9	negative selection	7824231
109087781	109087804	8	-	27260156	PANC0327	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.15713963516203577	[1117]	[1220,858,862,1526]	2	hSpCas9	negative selection	7824232
109088139	109088162	8	-	27260156	PANC0327	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.7268445486481482	[554]	[441,228,207,332]	-7	hSpCas9	negative selection	7824233
109087687	109087710	8	-	27260156	NCIH2009	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.6712726972909558	[458]	[1374,741,1019]	8	hSpCas9	negative selection	7881234
109087692	109087715	8	+	27260156	NCIH2009	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	1.4826314290537976	[266]	[1023,824,1276]	9	hSpCas9	negative selection	7881235
109119287	109119310	8	+	27260156	NCIH2009	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.256152845437392	[356]	[630,438,223]	-3	hSpCas9	negative selection	7881236
109119311	109119334	8	+	27260156	NCIH2009	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.3591007044248613	[1033]	[2346,1873,1431]	5	hSpCas9	negative selection	7945482
109087781	109087804	8	-	27260156	NCIH2009	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.06516955732623053	[1117]	[1938,1476,1148]	-1	hSpCas9	negative selection	7945483
109088139	109088162	8	-	27260156	NCIH2009	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.24555066320725769	[554]	[835,435,728]	-3	hSpCas9	negative selection	7945484
109087687	109087710	8	-	27260156	NCIH1373	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.5813916588098348	[458]	[677,663,533,322]	6	hSpCas9	negative selection	8002485
109087692	109087715	8	+	27260156	NCIH1373	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.4020962547642798	[266]	[573,273,226,146]	4	hSpCas9	negative selection	8002486
109119287	109119310	8	+	27260156	NCIH1373	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.4714564352722869	[356]	[368,249,317,59]	-5	hSpCas9	negative selection	8002487
109119311	109119334	8	+	27260156	NCIH1373	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.24233288798164643	[1033]	[1383,1071,1499,410]	2	hSpCas9	negative selection	8066733
109087781	109087804	8	-	27260156	NCIH1373	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.18071272206638445	[1117]	[1825,1098,1738,283]	1	hSpCas9	negative selection	8066734
109088139	109088162	8	-	27260156	NCIH1373	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.8144120112439757	[554]	[320,428,352,76]	-7	hSpCas9	negative selection	8066735
109087687	109087710	8	-	27260156	PATU8902	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.4899126987765315	[458]	[931,637,609,1555]	5	hSpCas9	negative selection	8123736
109087692	109087715	8	+	27260156	PATU8902	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.7429000380602835	[266]	[387,1024,465,653]	7	hSpCas9	negative selection	8123737
109119287	109119310	8	+	27260156	PATU8902	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.4798284840243869	[356]	[178,1150,519,1008]	5	hSpCas9	negative selection	8123738
109119311	109119334	8	+	27260156	PATU8902	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.19969746830415536	[1033]	[1237,1473,681,1829]	-2	hSpCas9	negative selection	8187984
109087781	109087804	8	-	27260156	PATU8902	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.3234781034934522	[1117]	[664,1751,1248,1317]	-3	hSpCas9	negative selection	8187985
109088139	109088162	8	-	27260156	PATU8902	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.37449249912312077	[554]	[728,834,138,821]	-4	hSpCas9	negative selection	8187986
109087687	109087710	8	-	27260156	PANC1	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.8080956083330039	[458]	[702,1011,665,470]	9	hSpCas9	negative selection	8244987
109087692	109087715	8	+	27260156	PANC1	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.7439950533872821	[266]	[585,262,381,285]	9	hSpCas9	negative selection	8244988
109119287	109119310	8	+	27260156	PANC1	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.21701510457768564	[356]	[208,366,452,390]	3	hSpCas9	negative selection	8244989
109119311	109119334	8	+	27260156	PANC1	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.1586695313763189	[1033]	[770,1261,1135,862]	2	hSpCas9	negative selection	8309235
109087781	109087804	8	-	27260156	PANC1	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.12719970779025003	[1117]	[850,1187,862,694]	-2	hSpCas9	negative selection	8309236
109088139	109088162	8	-	27260156	PANC1	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	0.12218544326091352	[554]	[455,535,852,270]	2	hSpCas9	negative selection	8309237
109087687	109087710	8	-	27260156	PANC0813	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.36987230770093593	[458]	[971,495,730,616]	6	hSpCas9	negative selection	8366238
109087692	109087715	8	+	27260156	PANC0813	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.4948554773134828	[266]	[341,473,600,346]	7	hSpCas9	negative selection	8366239
109119287	109119310	8	+	27260156	PANC0813	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.3190757926575318	[356]	[417,334,326,274]	-5	hSpCas9	negative selection	8366240
109119311	109119334	8	+	27260156	PANC0813	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.03215994953588219	[1033]	[1272,1344,1123,1023]	0	hSpCas9	negative selection	8430486
109087781	109087804	8	-	27260156	PANC0813	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.02729669113431399	[1117]	[1596,1189,1188,1208]	0	hSpCas9	negative selection	8430487
109088139	109088162	8	-	27260156	PANC0813	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.5860582721629759	[554]	[529,324,396,489]	-7	hSpCas9	negative selection	8430488
109087687	109087710	8	-	27260156	RDES	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.603121564175547	[458]	[611,729,792,1149]	8	hSpCas9	negative selection	8487489
109087692	109087715	8	+	27260156	RDES	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.4819043323936105	[266]	[434,373,423,478]	7	hSpCas9	negative selection	8487490
109119287	109119310	8	+	27260156	RDES	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.33772381402726853	[356]	[285,318,381,310]	-5	hSpCas9	negative selection	8487491
109119311	109119334	8	+	27260156	RDES	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.09262611203223248	[1033]	[1011,1129,1273,1762]	1	hSpCas9	negative selection	8551737
109087781	109087804	8	-	27260156	RDES	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.024991223984538458	[1117]	[981,1210,1531,1386]	0	hSpCas9	negative selection	8551738
109088139	109088162	8	-	27260156	RDES	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.717977039880584	[554]	[365,363,413,405]	-8	hSpCas9	negative selection	8551739
109087687	109087710	8	-	27260156	PC3	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.5169903015782464	[458]	[368,724,1066,681]	9	hSpCas9	negative selection	8608740
109087692	109087715	8	+	27260156	PC3	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.0700405355055389	[266]	[121,224,614,341]	1	hSpCas9	negative selection	8608741
109119287	109119310	8	+	27260156	PC3	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.1469055124821033	[356]	[168,555,848,232]	3	hSpCas9	negative selection	8608742
109119311	109119334	8	+	27260156	PC3	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.20081569097380758	[1033]	[641,847,1629,762]	-4	hSpCas9	negative selection	8672988
109087781	109087804	8	-	27260156	PC3	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.2654265406782529	[1117]	[631,645,1798,1025]	-6	hSpCas9	negative selection	8672989
109088139	109088162	8	-	27260156	PC3	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.46598615475893246	[554]	[275,438,550,403]	-8	hSpCas9	negative selection	8672990
109087687	109087710	8	-	27260156	PATU8988T	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.48839958000959266	[458]	[656,754,579,499]	7	hSpCas9	negative selection	8729991
109087692	109087715	8	+	27260156	PATU8988T	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.19839438723175418	[266]	[406,236,193,345]	3	hSpCas9	negative selection	8729992
109119287	109119310	8	+	27260156	PATU8988T	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.08982111994237257	[356]	[223,474,410,367]	1	hSpCas9	negative selection	8729993
109119311	109119334	8	+	27260156	PATU8988T	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.09426864419325076	[1033]	[856,889,953,1046]	-2	hSpCas9	negative selection	8794239
109087781	109087804	8	-	27260156	PATU8988T	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.3666924645878066	[1117]	[777,886,780,916]	-6	hSpCas9	negative selection	8794240
109088139	109088162	8	-	27260156	PATU8988T	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.769316673890854	[554]	[164,278,441,371]	-8	hSpCas9	negative selection	8794241
109087687	109087710	8	-	27260156	T47D	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.4287471284468003	[458]	[772,498,871,752]	8	hSpCas9	negative selection	8851242
109087692	109087715	8	+	27260156	T47D	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.21720968522563966	[266]	[326,317,332,475]	4	hSpCas9	negative selection	8851243
109119287	109119310	8	+	27260156	T47D	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.19503501546275676	[356]	[375,340,352,385]	-4	hSpCas9	negative selection	8851244
109119311	109119334	8	+	27260156	T47D	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.06574279396956229	[1033]	[1305,1152,1041,1102]	-1	hSpCas9	negative selection	8915490
109087781	109087804	8	-	27260156	T47D	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.057754254140548245	[1117]	[1362,959,1323,1386]	-1	hSpCas9	negative selection	8915491
109088139	109088162	8	-	27260156	T47D	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.4310812681923498	[554]	[588,395,402,540]	-7	hSpCas9	negative selection	8915492
109087687	109087710	8	-	27260156	SU8686	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.7038902101010305	[458]	[668,646,804,883]	9	hSpCas9	negative selection	8972493
109087692	109087715	8	+	27260156	SU8686	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.4713887488170662	[266]	[323,351,386,417]	7	hSpCas9	negative selection	8972494
109119287	109119310	8	+	27260156	SU8686	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.08894425857929222	[356]	[313,332,514,353]	1	hSpCas9	negative selection	8972495
109119311	109119334	8	+	27260156	SU8686	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.05494767770648967	[1033]	[1156,1132,920,1007]	0	hSpCas9	negative selection	9036741
109087781	109087804	8	-	27260156	SU8686	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.10396439868583562	[1117]	[1182,1020,1256,1344]	1	hSpCas9	negative selection	9036742
109088139	109088162	8	-	27260156	SU8686	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.14633062661341062	[554]	[463,427,480,648]	-3	hSpCas9	negative selection	9036743
109087687	109087710	8	-	27260156	SKES1	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.3859375824328214	[458]	[771,631,576,451]	7	hSpCas9	negative selection	9093744
109087692	109087715	8	+	27260156	SKES1	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	-0.40498874320752165	[266]	[215,216,236,142]	-7	hSpCas9	negative selection	9093745
109119287	109119310	8	+	27260156	SKES1	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.15356515550670174	[356]	[411,393,238,261]	-3	hSpCas9	negative selection	9093746
109119311	109119334	8	+	27260156	SKES1	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.0013215310384673273	[1033]	[964,1329,956,908]	0	hSpCas9	negative selection	9157992
109087781	109087804	8	-	27260156	SKES1	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.2053598184306522	[1117]	[807,1027,966,1032]	-4	hSpCas9	negative selection	9157993
109088139	109088162	8	-	27260156	SKES1	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.3064146953867943	[554]	[602,422,351,429]	-6	hSpCas9	negative selection	9157994
109087687	109087710	8	-	27260156	TOV112D	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.43594484735902367	[458]	[606,775,473,664]	7	hSpCas9	negative selection	9214995
109087692	109087715	8	+	27260156	TOV112D	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.1940377148084158	[266]	[260,374,353,247]	4	hSpCas9	negative selection	9214996
109119287	109119310	8	+	27260156	TOV112D	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.02752646169482098	[356]	[498,465,218,310]	0	hSpCas9	negative selection	9214997
109119311	109119334	8	+	27260156	TOV112D	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.05752427116472103	[1033]	[1044,1310,1082,928]	1	hSpCas9	negative selection	9279243
109087781	109087804	8	-	27260156	TOV112D	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	0.047138583412516644	[1117]	[942,1574,975,1214]	0	hSpCas9	negative selection	9279244
109088139	109088162	8	-	27260156	TOV112D	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.04768989497438059	[554]	[438,494,499,692]	-1	hSpCas9	negative selection	9279245
109087687	109087710	8	-	27260156	TC71	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.485571070829109	[458]	[609,666,698,786]	9	hSpCas9	negative selection	9336246
109087692	109087715	8	+	27260156	TC71	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.14755696684786612	[266]	[335,285,370,269]	4	hSpCas9	negative selection	9336247
109119287	109119310	8	+	27260156	TC71	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	0.027931104167243814	[356]	[394,386,403,372]	0	hSpCas9	negative selection	9336248
109119311	109119334	8	+	27260156	TC71	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	-0.17521763675015622	[1033]	[1063,922,890,1053]	-4	hSpCas9	negative selection	9400494
109087781	109087804	8	-	27260156	TC71	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.29971757886177997	[1117]	[906,1084,953,948]	-7	hSpCas9	negative selection	9400495
109088139	109088162	8	-	27260156	TC71	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.19818160371674387	[554]	[456,506,582,526]	-5	hSpCas9	negative selection	9400496
109087687	109087710	8	-	27260156	TC32	viability	CTCACCAGGTAGCAGTTTGTGGG	TRHR	ENSG00000174417	0.4478339195284884	[458]	[524,517,643,678]	7	hSpCas9	negative selection	9457497
109087692	109087715	8	+	27260156	TC32	viability	AAACTGCTACCTGGTGAGCCTGG	TRHR	ENSG00000174417	0.10197888236157504	[266]	[342,120,261,387]	1	hSpCas9	negative selection	9457498
109119287	109119310	8	+	27260156	TC32	viability	GAAACCTGCTAACTACAGTGTGG	TRHR	ENSG00000174417	-0.3961848190387905	[356]	[247,174,334,293]	-6	hSpCas9	negative selection	9457499
109119311	109119334	8	+	27260156	TC32	viability	CCTAAATTACAGCGTCATCAAGG	TRHR	ENSG00000174417	0.02277761700581893	[1033]	[925,787,1312,1001]	0	hSpCas9	negative selection	9521745
109087781	109087804	8	-	27260156	TC32	viability	TCCAACATAGCCATAGACCCAGG	TRHR	ENSG00000174417	-0.046659823699418235	[1117]	[824,936,1443,922]	-1	hSpCas9	negative selection	9521746
109088139	109088162	8	-	27260156	TC32	viability	TTCTAGCTATGAATCCATAGAGG	TRHR	ENSG00000174417	-0.27346049091322316	[554]	[357,414,513,441]	-5	hSpCas9	negative selection	9521747
109087584	109087607	8	-	27869803	HPAFII	viability after 27 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	1.0161286945478123	[134]	[136,148,NaN]	8	hSpCas9	negative selection	9600997
109087623	109087646	8	-	27869803	HPAFII	viability after 27 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.34521272960741456	[100]	[1,121,NaN]	2	hSpCas9	negative selection	9600998
109087653	109087676	8	-	27869803	HPAFII	viability after 27 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.5177796034630069	[274]	[266,156,NaN]	4	hSpCas9	negative selection	9600999
109088045	109088068	8	-	27869803	HPAFII	viability after 27 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.17724763647166838	[229]	[187,93,NaN]	1	hSpCas9	negative selection	9601000
109119188	109119211	8	+	27869803	HPAFII	viability after 27 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	-0.21095209583789265	[560]	[346,177,NaN]	-1	hSpCas9	negative selection	9601001
109087584	109087607	8	-	27869803	HPAFII	viability after 15 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	0.8707025137680696	[134]	[461,142,NaN]	8	hSpCas9	negative selection	9683446
109087623	109087646	8	-	27869803	HPAFII	viability after 15 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.48731719910737625	[100]	[145,155,NaN]	5	hSpCas9	negative selection	9683447
109087653	109087676	8	-	27869803	HPAFII	viability after 15 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.3780787159204416	[274]	[565,270,NaN]	4	hSpCas9	negative selection	9683448
109088045	109088068	8	-	27869803	HPAFII	viability after 15 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.04264830174617046	[229]	[298,226,NaN]	0	hSpCas9	negative selection	9683449
109119188	109119211	8	+	27869803	HPAFII	viability after 15 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.02013149198402009	[560]	[915,421,NaN]	0	hSpCas9	negative selection	9683450
109087584	109087607	8	-	27869803	ASPC1	viability after 36 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	0.8736453774800501	[356]	[73,637,8]	8	hSpCas9	negative selection	9765895
109087623	109087646	8	-	27869803	ASPC1	viability after 36 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.43352669183313153	[274]	[21,175,166]	4	hSpCas9	negative selection	9765896
109087653	109087676	8	-	27869803	ASPC1	viability after 36 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	-0.0881631796609378	[685]	[136,185,315]	-1	hSpCas9	negative selection	9765897
109088045	109088068	8	-	27869803	ASPC1	viability after 36 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.39118588138635274	[562]	[191,233,319]	4	hSpCas9	negative selection	9765898
109119188	109119211	8	+	27869803	ASPC1	viability after 36 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.03473368340955196	[1399]	[626,537,376]	0	hSpCas9	negative selection	9765899
109087584	109087607	8	-	27869803	PATU8988S	viability after 35 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	-0.2620581213816834	[443]	[200,96,NaN]	-3	hSpCas9	negative selection	9848344
109087623	109087646	8	-	27869803	PATU8988S	viability after 35 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-1.0447345369571779	[263]	[68,33,NaN]	-7	hSpCas9	negative selection	9848345
109087653	109087676	8	-	27869803	PATU8988S	viability after 35 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.6316114692113883	[408]	[345,163,NaN]	7	hSpCas9	negative selection	9848346
109088045	109088068	8	-	27869803	PATU8988S	viability after 35 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.171647131268997	[527]	[247,230,NaN]	2	hSpCas9	negative selection	9848347
109119188	109119211	8	+	27869803	PATU8988S	viability after 35 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.9116080083303507	[868]	[605,710,NaN]	8	hSpCas9	negative selection	9848348
109087584	109087607	8	-	27869803	PATU8988S	viability after 31 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	-0.1438344768042552	[443]	[172,143,NaN]	-2	hSpCas9	negative selection	9930793
109087623	109087646	8	-	27869803	PATU8988S	viability after 31 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-1.293032254069899	[263]	[38,47,NaN]	-8	hSpCas9	negative selection	9930794
109087653	109087676	8	-	27869803	PATU8988S	viability after 31 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.7256527281227265	[408]	[303,225,NaN]	8	hSpCas9	negative selection	9930795
109088045	109088068	8	-	27869803	PATU8988S	viability after 31 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.33029116438351847	[527]	[170,383,NaN]	4	hSpCas9	negative selection	9930796
109119188	109119211	8	+	27869803	PATU8988S	viability after 31 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	0.41544989945786936	[868]	[378,567,NaN]	5	hSpCas9	negative selection	9930797
109087584	109087607	8	-	27869803	HPAFII	viability after 35 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	1.2909904464952469	[134]	[162,171,NaN]	8	hSpCas9	negative selection	10013242
109087623	109087646	8	-	27869803	HPAFII	viability after 35 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.14117675377398808	[100]	[6,111,NaN]	0	hSpCas9	negative selection	10013243
109087653	109087676	8	-	27869803	HPAFII	viability after 35 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.5673205942650474	[274]	[313,84,NaN]	3	hSpCas9	negative selection	10013244
109088045	109088068	8	-	27869803	HPAFII	viability after 35 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.24301402722872656	[229]	[205,60,NaN]	1	hSpCas9	negative selection	10013245
109119188	109119211	8	+	27869803	HPAFII	viability after 35 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	-0.21324684783284964	[560]	[323,155,NaN]	-1	hSpCas9	negative selection	10013246
109087584	109087607	8	-	27869803	HPAFII	viability after 31 days	CAAGTAAGATGGTGACCACCTGG	TRHR	ENSG00000174417	0.9799367776436279	[134]	[147,150,NaN]	7	hSpCas9	negative selection	10095691
109087623	109087646	8	-	27869803	HPAFII	viability after 31 days	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.191533634478934	[100]	[7,94,NaN]	-1	hSpCas9	negative selection	10095692
109087653	109087676	8	-	27869803	HPAFII	viability after 31 days	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.32574049278062833	[274]	[269,109,NaN]	2	hSpCas9	negative selection	10095693
109088045	109088068	8	-	27869803	HPAFII	viability after 31 days	CCTGGAGATCTTGTAGCCACAGG	TRHR	ENSG00000174417	0.0493487814482773	[229]	[190,70,NaN]	0	hSpCas9	negative selection	10095694
109119188	109119211	8	+	27869803	HPAFII	viability after 31 days	TCTCAACAGTGCCATCAACCCGG	TRHR	ENSG00000174417	-0.05946694912795136	[560]	[304,298,NaN]	0	hSpCas9	negative selection	10095695
109087548	109087571	8	+	28162770	P31FUJ	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.3486458121305407	[136]	[204]	4	hSpCas9	negative selection	10256514
109087653	109087676	8	-	28162770	P31FUJ	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.5736901196857556	[477]	[835]	6	hSpCas9	negative selection	10256515
109087569	109087592	8	+	28162770	P31FUJ	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.7611811767691674	[149]	[103]	-5	hSpCas9	negative selection	10256516
109087623	109087646	8	-	28162770	P31FUJ	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.3379845275424097	[374]	[556]	3	hSpCas9	negative selection	10256517
109087806	109087829	8	-	28162770	P31FUJ	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	0.20269939742418086	[104]	[141]	2	hSpCas9	negative selection	10256518
109088029	109088052	8	+	28162770	P31FUJ	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	-0.32180721047312344	[233]	[219]	-3	hSpCas9	negative selection	10256519
109087899	109087922	8	-	28162770	P31FUJ	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	-0.34675839371146444	[78]	[72]	-3	hSpCas9	negative selection	10256520
109087859	109087882	8	+	28162770	P31FUJ	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.4187508278978993	[500]	[786]	5	hSpCas9	negative selection	10256521
109087910	109087933	8	-	28162770	P31FUJ	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	-0.32962310036295206	[492]	[460]	-3	hSpCas9	negative selection	10256522
109088119	109088142	8	-	28162770	P31FUJ	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	0.9353981165584728	[92]	[208]	9	hSpCas9	negative selection	10256523
109087548	109087571	8	+	28162770	TF1	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10425880
109087653	109087676	8	-	28162770	TF1	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	NaN	[NaN]	[501]	1	hSpCas9	negative selection	10425881
109087569	109087592	8	+	28162770	TF1	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10425882
109087623	109087646	8	-	28162770	TF1	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	NaN	[NaN]	[267]	1	hSpCas9	negative selection	10425883
109087806	109087829	8	-	28162770	TF1	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10425884
109088029	109088052	8	+	28162770	TF1	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10425885
109087899	109087922	8	-	28162770	TF1	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	NaN	[NaN]	[33]	1	hSpCas9	negative selection	10425886
109087859	109087882	8	+	28162770	TF1	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	NaN	[NaN]	[476]	1	hSpCas9	negative selection	10425887
109087910	109087933	8	-	28162770	TF1	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	NaN	[NaN]	[394]	1	hSpCas9	negative selection	10425888
109088119	109088142	8	-	28162770	TF1	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	NaN	[NaN]	[139]	1	hSpCas9	negative selection	10425889
109087548	109087571	8	+	28162770	SKM1	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.37237634714484574	[51]	[118]	3	hSpCas9	negative selection	10595246
109087653	109087676	8	-	28162770	SKM1	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.5880177264902136	[107]	[286]	5	hSpCas9	negative selection	10595247
109087569	109087592	8	+	28162770	SKM1	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	0.13492958008610856	[33]	[65]	1	hSpCas9	negative selection	10595248
109087623	109087646	8	-	28162770	SKM1	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.5604679388004075	[111]	[291]	5	hSpCas9	negative selection	10595249
109087806	109087829	8	-	28162770	SKM1	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	-0.3480705096895933	[17]	[24]	-3	hSpCas9	negative selection	10595250
109088029	109088052	8	+	28162770	SKM1	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	-0.6637396141052733	[68]	[76]	-5	hSpCas9	negative selection	10595251
109087899	109087922	8	-	28162770	SKM1	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	0.3355395789644745	[25]	[57]	3	hSpCas9	negative selection	10595252
109087859	109087882	8	+	28162770	SKM1	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.8513987673667345	[115]	[369]	7	hSpCas9	negative selection	10595253
109087910	109087933	8	-	28162770	SKM1	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	-0.5224414161630977	[103]	[127]	-4	hSpCas9	negative selection	10595254
109088119	109088142	8	-	28162770	SKM1	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	0.7040671136455822	[24]	[71]	6	hSpCas9	negative selection	10595255
109087548	109087571	8	+	28162770	SKM1	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.37237634714484574	[51]	[118]	3	hSpCas9	negative selection	10764612
109087653	109087676	8	-	28162770	SKM1	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.5880177264902136	[107]	[286]	5	hSpCas9	negative selection	10764613
109087569	109087592	8	+	28162770	SKM1	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	0.13492958008610856	[33]	[65]	1	hSpCas9	negative selection	10764614
109087623	109087646	8	-	28162770	SKM1	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.5604679388004075	[111]	[291]	5	hSpCas9	negative selection	10764615
109087806	109087829	8	-	28162770	SKM1	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	-0.3480705096895933	[17]	[24]	-3	hSpCas9	negative selection	10764616
109088029	109088052	8	+	28162770	SKM1	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	-0.6637396141052733	[68]	[76]	-5	hSpCas9	negative selection	10764617
109087899	109087922	8	-	28162770	SKM1	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	0.3355395789644745	[25]	[57]	3	hSpCas9	negative selection	10764618
109087859	109087882	8	+	28162770	SKM1	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.8513987673667345	[115]	[369]	7	hSpCas9	negative selection	10764619
109087910	109087933	8	-	28162770	SKM1	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	-0.5224414161630977	[103]	[127]	-4	hSpCas9	negative selection	10764620
109088119	109088142	8	-	28162770	SKM1	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	0.7040671136455822	[24]	[71]	6	hSpCas9	negative selection	10764621
109087548	109087571	8	+	28162770	PL21	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.5917181409441751	[185]	[121]	5	hSpCas9	negative selection	10933978
109087653	109087676	8	-	28162770	PL21	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	-0.3466877573450649	[335]	[114]	-2	hSpCas9	negative selection	10933979
109087569	109087592	8	+	28162770	PL21	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.9830822095664501	[217]	[47]	-6	hSpCas9	negative selection	10933980
109087623	109087646	8	-	28162770	PL21	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.6264043691914183	[447]	[300]	5	hSpCas9	negative selection	10933981
109087806	109087829	8	-	28162770	PL21	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	0.45793737195696693	[91]	[54]	4	hSpCas9	negative selection	10933982
109088029	109088052	8	+	28162770	PL21	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	0.1944259632949265	[252]	[125]	1	hSpCas9	negative selection	10933983
109087899	109087922	8	-	28162770	PL21	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	-1.1217884803980422	[59]	[11]	-6	hSpCas9	negative selection	10933984
109087859	109087882	8	+	28162770	PL21	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.4713248614439779	[352]	[212]	4	hSpCas9	negative selection	10933985
109087910	109087933	8	-	28162770	PL21	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	0.7724282851753655	[342]	[254]	6	hSpCas9	negative selection	10933986
109088119	109088142	8	-	28162770	PL21	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	0.5882100661678945	[80]	[52]	5	hSpCas9	negative selection	10933987
109087548	109087571	8	+	28162770	P31FUJ	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.3486458121305407	[136]	[204]	4	hSpCas9	negative selection	11103344
109087653	109087676	8	-	28162770	P31FUJ	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.5736901196857556	[477]	[835]	6	hSpCas9	negative selection	11103345
109087569	109087592	8	+	28162770	P31FUJ	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.7611811767691674	[149]	[103]	-5	hSpCas9	negative selection	11103346
109087623	109087646	8	-	28162770	P31FUJ	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.3379845275424097	[374]	[556]	3	hSpCas9	negative selection	11103347
109087806	109087829	8	-	28162770	P31FUJ	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	0.20269939742418086	[104]	[141]	2	hSpCas9	negative selection	11103348
109088029	109088052	8	+	28162770	P31FUJ	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	-0.32180721047312344	[233]	[219]	-3	hSpCas9	negative selection	11103349
109087899	109087922	8	-	28162770	P31FUJ	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	-0.34675839371146444	[78]	[72]	-3	hSpCas9	negative selection	11103350
109087859	109087882	8	+	28162770	P31FUJ	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.4187508278978993	[500]	[786]	5	hSpCas9	negative selection	11103351
109087910	109087933	8	-	28162770	P31FUJ	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	-0.32962310036295206	[492]	[460]	-3	hSpCas9	negative selection	11103352
109088119	109088142	8	-	28162770	P31FUJ	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	0.9353981165584728	[92]	[208]	9	hSpCas9	negative selection	11103353
109087548	109087571	8	+	28162770	OCIAML5	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	1.1868524184283054	[63]	[262]	8	hSpCas9	negative selection	11272710
109087653	109087676	8	-	28162770	OCIAML5	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.7656858649748288	[260]	[800]	6	hSpCas9	negative selection	11272711
109087569	109087592	8	+	28162770	OCIAML5	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.7937679302993299	[96]	[100]	-5	hSpCas9	negative selection	11272712
109087623	109087646	8	-	28162770	OCIAML5	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.07332036836191103	[247]	[470]	0	hSpCas9	negative selection	11272713
109087806	109087829	8	-	28162770	OCIAML5	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	0.5953924061072244	[32]	[89]	5	hSpCas9	negative selection	11272714
109088029	109088052	8	+	28162770	OCIAML5	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	0.7328959298571591	[108]	[326]	6	hSpCas9	negative selection	11272715
109087899	109087922	8	-	28162770	OCIAML5	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	-2.014337999762874	[46]	[20]	-8	hSpCas9	negative selection	11272716
109087859	109087882	8	+	28162770	OCIAML5	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.3178584305783154	[395]	[890]	2	hSpCas9	negative selection	11272717
109087910	109087933	8	-	28162770	OCIAML5	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	-0.32361609123349355	[268]	[387]	-2	hSpCas9	negative selection	11272718
109088119	109088142	8	-	28162770	OCIAML5	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	0.3703258504724509	[41]	[97]	3	hSpCas9	negative selection	11272719
109087548	109087571	8	+	28162770	EOL1	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	1.0651159699533013	[341]	[376]	8	hSpCas9	negative selection	11442076
109087653	109087676	8	-	28162770	EOL1	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	-0.5226315862427441	[468]	[171]	-4	hSpCas9	negative selection	11442077
109087569	109087592	8	+	28162770	EOL1	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	0.023010410456222846	[268]	[143]	0	hSpCas9	negative selection	11442078
109087623	109087646	8	-	28162770	EOL1	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.07055896752291302	[882]	[442]	0	hSpCas9	negative selection	11442079
109087806	109087829	8	-	28162770	EOL1	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	1.7546227701282222	[161]	[287]	9	hSpCas9	negative selection	11442080
109088029	109088052	8	+	28162770	EOL1	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	-0.2461090052062037	[492]	[218]	-2	hSpCas9	negative selection	11442081
109087899	109087922	8	-	28162770	EOL1	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	0.7952647546255682	[69]	[63]	7	hSpCas9	negative selection	11442082
109087859	109087882	8	+	28162770	EOL1	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	-0.09318531435448796	[572]	[282]	0	hSpCas9	negative selection	11442083
109087910	109087933	8	-	28162770	EOL1	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	0.6554579736741931	[381]	[316]	6	hSpCas9	negative selection	11442084
109088119	109088142	8	-	28162770	EOL1	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	1.6911842324130835	[76]	[130]	9	hSpCas9	negative selection	11442085
109087548	109087571	8	+	28162770	MOLM13	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	-0.7085371858396887	[277]	[122]	-4	hSpCas9	negative selection	11611442
109087653	109087676	8	-	28162770	MOLM13	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.3398559922575497	[576]	[527]	2	hSpCas9	negative selection	11611443
109087569	109087592	8	+	28162770	MOLM13	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.8379190479795067	[266]	[107]	-4	hSpCas9	negative selection	11611444
109087623	109087646	8	-	28162770	MOLM13	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.1366834730692057	[623]	[495]	1	hSpCas9	negative selection	11611445
109087806	109087829	8	-	28162770	MOLM13	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	0.0342362040983879	[103]	[76]	0	hSpCas9	negative selection	11611446
109088029	109088052	8	+	28162770	MOLM13	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	1.0555063357117132	[361]	[543]	7	hSpCas9	negative selection	11611447
109087899	109087922	8	-	28162770	MOLM13	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	-0.5321106184554214	[71]	[35]	-3	hSpCas9	negative selection	11611448
109087859	109087882	8	+	28162770	MOLM13	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	-0.7988153389296347	[550]	[228]	-4	hSpCas9	negative selection	11611449
109087910	109087933	8	-	28162770	MOLM13	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	-0.593949872273284	[571]	[273]	-3	hSpCas9	negative selection	11611450
109088119	109088142	8	-	28162770	MOLM13	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	0.11698221968545064	[87]	[68]	0	hSpCas9	negative selection	11611451
109087548	109087571	8	+	28162770	HEL	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.4803083671049687	[215]	[192]	4	hSpCas9	negative selection	11780808
109087653	109087676	8	-	28162770	HEL	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.9491006694982514	[409]	[506]	8	hSpCas9	negative selection	11780809
109087569	109087592	8	+	28162770	HEL	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.7039116922982367	[205]	[80]	-4	hSpCas9	negative selection	11780810
109087623	109087646	8	-	28162770	HEL	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.22492958347145953	[520]	[389]	1	hSpCas9	negative selection	11780811
109087806	109087829	8	-	28162770	HEL	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	0.8459531516529402	[118]	[136]	7	hSpCas9	negative selection	11780812
109088029	109088052	8	+	28162770	HEL	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	0.5531016195156804	[331]	[311]	5	hSpCas9	negative selection	11780813
109087899	109087922	8	-	28162770	HEL	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	0.33239871138820654	[61]	[49]	2	hSpCas9	negative selection	11780814
109087859	109087882	8	+	28162770	HEL	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.3816140161751942	[452]	[377]	3	hSpCas9	negative selection	11780815
109087910	109087933	8	-	28162770	HEL	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	0.29794162956676973	[460]	[362]	2	hSpCas9	negative selection	11780816
109088119	109088142	8	-	28162770	HEL	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	0.3598048687288582	[72]	[59]	3	hSpCas9	negative selection	11780817
109087548	109087571	8	+	28162770	MV411	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	-0.5079400804973112	[183]	[108]	-4	hSpCas9	negative selection	11950174
109087653	109087676	8	-	28162770	MV411	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.5732490801573658	[370]	[464]	5	hSpCas9	negative selection	11950175
109087569	109087592	8	+	28162770	MV411	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.7719277740841558	[149]	[73]	-5	hSpCas9	negative selection	11950176
109087623	109087646	8	-	28162770	MV411	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.18844673340167284	[394]	[291]	-1	hSpCas9	negative selection	11950177
109087806	109087829	8	-	28162770	MV411	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	0.5934334056319678	[106]	[135]	5	hSpCas9	negative selection	11950178
109088029	109088052	8	+	28162770	MV411	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	0.05311589503299591	[245]	[214]	0	hSpCas9	negative selection	11950179
109087899	109087922	8	-	28162770	MV411	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	-1.2018698505808145	[70]	[25]	-7	hSpCas9	negative selection	11950180
109087859	109087882	8	+	28162770	MV411	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.4052134695589713	[423]	[472]	3	hSpCas9	negative selection	11950181
109087910	109087933	8	-	28162770	MV411	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	0.3221142370772715	[319]	[336]	3	hSpCas9	negative selection	11950182
109088119	109088142	8	-	28162770	MV411	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	-0.0521227310761323	[79]	[64]	0	hSpCas9	negative selection	11950183
109087548	109087571	8	+	28162770	MONOMAC1	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.8029631529404462	[113]	[227]	7	hSpCas9	negative selection	12119540
109087653	109087676	8	-	28162770	MONOMAC1	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.3036093677281272	[228]	[323]	3	hSpCas9	negative selection	12119541
109087569	109087592	8	+	28162770	MONOMAC1	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	-0.628753087485028	[115]	[85]	-5	hSpCas9	negative selection	12119542
109087623	109087646	8	-	28162770	MONOMAC1	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.1730131974459801	[341]	[441]	1	hSpCas9	negative selection	12119543
109087806	109087829	8	-	28162770	MONOMAC1	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	-0.04503375361450368	[62]	[69]	0	hSpCas9	negative selection	12119544
109088029	109088052	8	+	28162770	MONOMAC1	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	0.7556574381620897	[185]	[359]	7	hSpCas9	negative selection	12119545
109087899	109087922	8	-	28162770	MONOMAC1	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	0.14809863898913367	[36]	[46]	1	hSpCas9	negative selection	12119546
109087859	109087882	8	+	28162770	MONOMAC1	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.8491986191230672	[260]	[538]	7	hSpCas9	negative selection	12119547
109087910	109087933	8	-	28162770	MONOMAC1	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	0.3439823060740054	[199]	[290]	3	hSpCas9	negative selection	12119548
109088119	109088142	8	-	28162770	MONOMAC1	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	0.7127653439688679	[32]	[61]	6	hSpCas9	negative selection	12119549
109087548	109087571	8	+	28162770	OCIAML2	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	0.03671177835652103	[34]	[198]	0	hSpCas9	negative selection	12288906
109087653	109087676	8	-	28162770	OCIAML2	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	0.12645623456148436	[78]	[477]	1	hSpCas9	negative selection	12288907
109087569	109087592	8	+	28162770	OCIAML2	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	0.3693297622473706	[24]	[178]	3	hSpCas9	negative selection	12288908
109087623	109087646	8	-	28162770	OCIAML2	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	0.39405827188139453	[73]	[538]	4	hSpCas9	negative selection	12288909
109087806	109087829	8	-	28162770	OCIAML2	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	-0.02840749663708686	[22]	[124]	0	hSpCas9	negative selection	12288910
109088029	109088052	8	+	28162770	OCIAML2	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	0.1722800246882744	[60]	[380]	1	hSpCas9	negative selection	12288911
109087899	109087922	8	-	28162770	OCIAML2	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	-1.923142029939668	[12]	[18]	-8	hSpCas9	negative selection	12288912
109087859	109087882	8	+	28162770	OCIAML2	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.31113338291270176	[64]	[446]	3	hSpCas9	negative selection	12288913
109087910	109087933	8	-	28162770	OCIAML2	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	0.2652745735537345	[67]	[452]	2	hSpCas9	negative selection	12288914
109088119	109088142	8	-	28162770	OCIAML2	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	1.229809892898931	[11]	[155]	9	hSpCas9	negative selection	12288915
109087548	109087571	8	+	28162770	OCIAML3	viability	ACAGCTTCAGCCACGAGCAGTGG	TRHR	ENSG00000174417	-0.8628243987519629	[49]	[82]	-6	hSpCas9	negative selection	12458272
109087653	109087676	8	-	28162770	OCIAML3	viability	GCTTGGTTCTCATGACAACCAGG	TRHR	ENSG00000174417	-0.16280120415180788	[121]	[328]	-1	hSpCas9	negative selection	12458273
109087569	109087592	8	+	28162770	OCIAML3	viability	GGTGGCCTTAGAATACCAGGTGG	TRHR	ENSG00000174417	0.014801602351360577	[39]	[121]	0	hSpCas9	negative selection	12458274
109087623	109087646	8	-	28162770	OCIAML3	viability	TGATGTTGCCTACAATGCCCAGG	TRHR	ENSG00000174417	-0.3812332215493124	[128]	[298]	-3	hSpCas9	negative selection	12458275
109087806	109087829	8	-	28162770	OCIAML3	viability	ACTGGAGGTAAGTAATGCAGAGG	TRHR	ENSG00000174417	0.21334728173344086	[31]	[111]	2	hSpCas9	negative selection	12458276
109088029	109088052	8	+	28162770	OCIAML3	viability	GATGCTATTGTGATATCCTGTGG	TRHR	ENSG00000174417	0.6377226455916211	[65]	[309]	6	hSpCas9	negative selection	12458277
109087899	109087922	8	-	28162770	OCIAML3	viability	AGAGAAACTGGGCTTTGATGGGG	TRHR	ENSG00000174417	-0.9773362798756688	[14]	[22]	-6	hSpCas9	negative selection	12458278
109087859	109087882	8	+	28162770	OCIAML3	viability	TAACAGCCTTTACCATTGAGAGG	TRHR	ENSG00000174417	0.8183754055087027	[101]	[542]	7	hSpCas9	negative selection	12458279
109087910	109087933	8	-	28162770	OCIAML3	viability	GGAAAATGTGCAGAGAAACTGGG	TRHR	ENSG00000174417	0.2956049638525198	[111]	[414]	2	hSpCas9	negative selection	12458280
109088119	109088142	8	-	28162770	OCIAML3	viability	AGGACGGTAGCCAGGATCATTGG	TRHR	ENSG00000174417	-0.5615861626317857	[21]	[44]	-4	hSpCas9	negative selection	12458281