Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:375593
• Symbol:TRIM73
• Description:tripartite motif containing 73

DataSource: http://genomecrispr.dkfz.de/#!/results/TRIM73

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
75399304	75399327	7	-	26472758	Jiyoye	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-0.06816262804078477	[56]	[40]	0	hSpCas9	negative selection	172865
75398969	75398992	7	-	26472758	Jiyoye	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-2.103786537771506	[113]	[19]	-8	hSpCas9	negative selection	172867
75398951	75398974	7	-	26472758	Jiyoye	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.38879685219101867	[78]	[77]	3	hSpCas9	negative selection	172869
75403674	75403697	7	+	26472758	Jiyoye	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-4.722107635439093	[34]	[0]	-9	hSpCas9	negative selection	172870
75404892	75404915	7	-	26472758	Jiyoye	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-1.603291617545195	[414]	[102]	-8	hSpCas9	negative selection	172872
75398990	75399013	7	-	26472758	Jiyoye	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	0.19068356160910982	[243]	[209]	1	hSpCas9	negative selection	172875
75399029	75399052	7	-	26472758	Jiyoye	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.4686046815626146	[366]	[199]	-3	hSpCas9	negative selection	172877
75399058	75399081	7	-	26472758	Jiyoye	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	1.60648418972928	[53]	[123]	8	hSpCas9	negative selection	172879
75399142	75399165	7	-	26472758	Jiyoye	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	5.314065977114391	[1]	[59]	9	hSpCas9	negative selection	172880
75399006	75399029	7	+	26472758	Jiyoye	viability	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	-0.3015933208296806	[303]	[185]	-2	hSpCas9	negative selection	172883
75403674	75403697	7	+	26472758	Jiyoye	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-4.722107635439093	[34]	[0]	-9	hSpCas9	negative selection	172885
75404892	75404915	7	-	26472758	Jiyoye	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-1.603291617545195	[414]	[102]	-8	hSpCas9	negative selection	172888
75398990	75399013	7	-	26472758	Jiyoye	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	0.19068356160910982	[243]	[209]	1	hSpCas9	negative selection	172890
75399029	75399052	7	-	26472758	Jiyoye	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.4686046815626146	[366]	[199]	-3	hSpCas9	negative selection	172892
75399058	75399081	7	-	26472758	Jiyoye	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	1.60648418972928	[53]	[123]	8	hSpCas9	negative selection	172894
75399142	75399165	7	-	26472758	Jiyoye	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	5.314065977114391	[1]	[59]	9	hSpCas9	negative selection	172896
75399304	75399327	7	-	26472758	Jiyoye	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-0.06816262804078477	[56]	[40]	0	hSpCas9	negative selection	172897
75405051	75405074	7	-	26472758	Jiyoye	viability	TCACCCAGATGAACTCATGGTGG	TRIM73	ENSG00000178809	-0.2852819515208245	[382]	[236]	-2	hSpCas9	negative selection	172900
75399304	75399327	7	-	26472758	KBM7	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-1.7853043183297301	[161,262]	[32,26]	-8	hSpCas9	negative selection	363983
75398969	75398992	7	-	26472758	KBM7	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-1.2792283566146443	[455,317]	[83,64]	-7	hSpCas9	negative selection	363985
75398951	75398974	7	-	26472758	KBM7	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.1017054463641228	[493,454]	[313,172]	1	hSpCas9	negative selection	363987
75403674	75403697	7	+	26472758	KBM7	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-5.008964219553605	[382,240]	[4,3]	-9	hSpCas9	negative selection	363988
75404892	75404915	7	-	26472758	KBM7	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.5890838433012442	[1172,782]	[235,358]	-5	hSpCas9	negative selection	363990
75398990	75399013	7	-	26472758	KBM7	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-0.9462793765979285	[1009,596]	[184,197]	-6	hSpCas9	negative selection	363993
75399029	75399052	7	-	26472758	KBM7	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.5786839061993669	[1032,1068]	[293,367]	-5	hSpCas9	negative selection	363995
75399058	75399081	7	-	26472758	KBM7	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.6128735496972351	[551,709]	[160,229]	-5	hSpCas9	negative selection	363997
75399142	75399165	7	-	26472758	KBM7	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	-0.9295536281305549	[395,273]	[70,90]	-6	hSpCas9	negative selection	363998
75399006	75399029	7	+	26472758	KBM7	viability	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	-0.41931512311771385	[936,836]	[309,312]	-4	hSpCas9	negative selection	364001
75403674	75403697	7	+	26472758	KBM7	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-5.008964219553605	[382,240]	[4,3]	-9	hSpCas9	negative selection	364003
75404892	75404915	7	-	26472758	KBM7	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.5890838433012442	[1172,782]	[235,358]	-5	hSpCas9	negative selection	364006
75398990	75399013	7	-	26472758	KBM7	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-0.9462793765979285	[1009,596]	[184,197]	-6	hSpCas9	negative selection	364008
75399029	75399052	7	-	26472758	KBM7	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.5786839061993669	[1032,1068]	[293,367]	-5	hSpCas9	negative selection	364010
75399058	75399081	7	-	26472758	KBM7	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.6128735496972351	[551,709]	[160,229]	-5	hSpCas9	negative selection	364012
75399142	75399165	7	-	26472758	KBM7	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	-0.9295536281305549	[395,273]	[70,90]	-6	hSpCas9	negative selection	364014
75399304	75399327	7	-	26472758	KBM7	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-1.7853043183297301	[161,262]	[32,26]	-8	hSpCas9	negative selection	364015
75405051	75405074	7	-	26472758	KBM7	viability	TCACCCAGATGAACTCATGGTGG	TRIM73	ENSG00000178809	-0.6523293856101184	[1022,1217]	[380,302]	-5	hSpCas9	negative selection	364018
75399304	75399327	7	-	26472758	Raji	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-1.1463730568721835	[123]	[12]	-7	hSpCas9	negative selection	555101
75398969	75398992	7	-	26472758	Raji	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-0.5791169918096191	[205]	[31]	-4	hSpCas9	negative selection	555103
75398951	75398974	7	-	26472758	Raji	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.5736256528185912	[294]	[45]	-4	hSpCas9	negative selection	555105
75403674	75403697	7	+	26472758	Raji	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-5.062541466068713	[143]	[0]	-9	hSpCas9	negative selection	555106
75404892	75404915	7	-	26472758	Raji	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.15501123620414425	[450]	[93]	-1	hSpCas9	negative selection	555108
75398990	75399013	7	-	26472758	Raji	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-0.38248919682783455	[454]	[80]	-3	hSpCas9	negative selection	555111
75399029	75399052	7	-	26472758	Raji	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	0.074962057681222	[359]	[87]	0	hSpCas9	negative selection	555113
75399058	75399081	7	-	26472758	Raji	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.8586691327030628	[335]	[42]	-6	hSpCas9	negative selection	555115
75399142	75399165	7	-	26472758	Raji	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	-0.1428430941595742	[156]	[32]	-1	hSpCas9	negative selection	555116
75399006	75399029	7	+	26472758	Raji	viability	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.13539791154319603	[407]	[103]	1	hSpCas9	negative selection	555119
75403674	75403697	7	+	26472758	Raji	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-5.062541466068713	[143]	[0]	-9	hSpCas9	negative selection	555121
75404892	75404915	7	-	26472758	Raji	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.15501123620414425	[450]	[93]	-1	hSpCas9	negative selection	555124
75398990	75399013	7	-	26472758	Raji	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-0.38248919682783455	[454]	[80]	-3	hSpCas9	negative selection	555126
75399029	75399052	7	-	26472758	Raji	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	0.074962057681222	[359]	[87]	0	hSpCas9	negative selection	555128
75399058	75399081	7	-	26472758	Raji	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.8586691327030628	[335]	[42]	-6	hSpCas9	negative selection	555130
75399142	75399165	7	-	26472758	Raji	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	-0.1428430941595742	[156]	[32]	-1	hSpCas9	negative selection	555132
75399304	75399327	7	-	26472758	Raji	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-1.1463730568721835	[123]	[12]	-7	hSpCas9	negative selection	555133
75405051	75405074	7	-	26472758	Raji	viability	TCACCCAGATGAACTCATGGTGG	TRIM73	ENSG00000178809	-0.24652376404483212	[592]	[115]	-2	hSpCas9	negative selection	555136
75399304	75399327	7	-	26472758	K562	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-0.4243753638581802	[123]	[77]	-3	hSpCas9	negative selection	746219
75398969	75398992	7	-	26472758	K562	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-0.793055977752216	[311]	[151]	-5	hSpCas9	negative selection	746221
75398951	75398974	7	-	26472758	K562	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.35261746818086837	[320]	[345]	2	hSpCas9	negative selection	746223
75403674	75403697	7	+	26472758	K562	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-7.625945991916957	[233]	[0]	-9	hSpCas9	negative selection	746224
75404892	75404915	7	-	26472758	K562	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-1.5104687744970218	[755]	[223]	-6	hSpCas9	negative selection	746226
75398990	75399013	7	-	26472758	K562	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-1.3349410668253332	[513]	[171]	-6	hSpCas9	negative selection	746229
75399029	75399052	7	-	26472758	K562	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	0.06729938230906907	[778]	[688]	0	hSpCas9	negative selection	746231
75399058	75399081	7	-	26472758	K562	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-1.6558992140185855	[656]	[175]	-7	hSpCas9	negative selection	746233
75399142	75399165	7	-	26472758	K562	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	0.051773649724051074	[175]	[153]	0	hSpCas9	negative selection	746234
75399006	75399029	7	+	26472758	K562	viability	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.3104239127065995	[768]	[804]	2	hSpCas9	negative selection	746237
75403674	75403697	7	+	26472758	K562	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-7.625945991916957	[233]	[0]	-9	hSpCas9	negative selection	746239
75404892	75404915	7	-	26472758	K562	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-1.5104687744970218	[755]	[223]	-6	hSpCas9	negative selection	746242
75398990	75399013	7	-	26472758	K562	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-1.3349410668253332	[513]	[171]	-6	hSpCas9	negative selection	746244
75399029	75399052	7	-	26472758	K562	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	0.06729938230906907	[778]	[688]	0	hSpCas9	negative selection	746246
75399058	75399081	7	-	26472758	K562	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-1.6558992140185855	[656]	[175]	-7	hSpCas9	negative selection	746248
75399142	75399165	7	-	26472758	K562	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	0.051773649724051074	[175]	[153]	0	hSpCas9	negative selection	746250
75399304	75399327	7	-	26472758	K562	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-0.4243753638581802	[123]	[77]	-3	hSpCas9	negative selection	746251
75405051	75405074	7	-	26472758	K562	viability	TCACCCAGATGAACTCATGGTGG	TRIM73	ENSG00000178809	0.24778165469241054	[856]	[858]	2	hSpCas9	negative selection	746254
75410137	75410160	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCGTTTCGCCACTTCTTCTCCAG	TRIM73	ENSG00000178809	0.07110529825958334	[78,39]	[21,3]	0	dCas9-VP64	positive selection	2405719
75397992	75398015	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCTGCTCTGATAACATTCAAG	TRIM73	ENSG00000178809	-2.2134967875984226	[88,165]	[7,2]	-9	dCas9-VP64	positive selection	2420728
75398038	75398061	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGGAAACTGGGTTACATCACAG	TRIM73	ENSG00000178809	1.455861811666864	[51,5]	[30,1]	5	dCas9-VP64	positive selection	2420731
75408849	75408872	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCTCAGCTACTTGG	TRIM73	ENSG00000178809	-0.32009396436001514	[73,465]	[65,28]	-1	dCas9-VP64	positive selection	2454663
75395530	75395553	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGAGCGCACAAAACATGATGGG	TRIM73	ENSG00000178809	-0.981117184804992	[149,15]	[13,2]	-6	dCas9-VP64	positive selection	2475091
75395471	75395494	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGTAGTTCCAGAGCTCGCGAGG	TRIM73	ENSG00000178809	-0.3443933345449207	[54,221]	[22,24]	-2	dCas9-VP64	positive selection	2475093
75395499	75395522	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCACGGTGAGTTGCCAGGTGTGG	TRIM73	ENSG00000178809	0.42069732914713365	[32,144]	[11,40]	1	dCas9-VP64	positive selection	2475094
75410137	75410160	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCGTTTCGCCACTTCTTCTCCAG	TRIM73	ENSG00000178809	-0.10198351627178981	[79,113]	[33,23]	-1	dCas9-VP64	positive selection	2500974
75397992	75398015	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCTGCTCTGATAACATTCAAG	TRIM73	ENSG00000178809	1.7542580013229494	[22,81]	[11,99]	8	dCas9-VP64	positive selection	2515983
75398038	75398061	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGGAAACTGGGTTACATCACAG	TRIM73	ENSG00000178809	-1.3503856352620804	[21,83]	[7,4]	-9	dCas9-VP64	positive selection	2515986
75408849	75408872	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCTCAGCTACTTGG	TRIM73	ENSG00000178809	-0.35714226545986627	[161,80]	[51,10]	-4	dCas9-VP64	positive selection	2549918
75395530	75395553	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGAGCGCACAAAACATGATGGG	TRIM73	ENSG00000178809	1.070583754643693	[34,30]	[15,28]	6	dCas9-VP64	positive selection	2570346
75395471	75395494	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGTAGTTCCAGAGCTCGCGAGG	TRIM73	ENSG00000178809	-0.03702372644070759	[76,122]	[24,36]	0	dCas9-VP64	positive selection	2570348
75395499	75395522	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCACGGTGAGTTGCCAGGTGTGG	TRIM73	ENSG00000178809	0.8111460386950384	[47,52]	[12,42]	5	dCas9-VP64	positive selection	2570349
75399007	75399030	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.11734021291172875	[4,4]	[3,4]	2	hSpCas9	positive selection	3029293
75399007	75399030	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.11734021291172875	[4,4]	[3,4]	2	hSpCas9	positive selection	3029294
75399007	75399030	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.11734021291172875	[4,4]	[3,4]	2	hSpCas9	positive selection	3029295
75399007	75399030	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.11734021291172875	[4,4]	[3,4]	2	hSpCas9	positive selection	3029296
75398951	75398974	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.3737919110450073	[3,3]	[2,1]	-5	hSpCas9	positive selection	3029297
75398976	75398999	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	0.29125444112609944	[4,4]	[4,4]	6	hSpCas9	positive selection	3029298
75398976	75398999	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	0.29125444112609944	[4,4]	[4,4]	6	hSpCas9	positive selection	3029299
75398976	75398999	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	0.29125444112609944	[4,4]	[4,4]	6	hSpCas9	positive selection	3029300
75398976	75398999	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	0.29125444112609944	[4,4]	[4,4]	6	hSpCas9	positive selection	3029301
75399007	75399030	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.5134592532229127	[4,4]	[5,4]	8	hSpCas9	positive selection	3097151
75399007	75399030	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.5134592532229127	[4,4]	[5,4]	8	hSpCas9	positive selection	3097152
75399007	75399030	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.5134592532229127	[4,4]	[5,4]	8	hSpCas9	positive selection	3097153
75399007	75399030	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.5134592532229127	[4,4]	[5,4]	8	hSpCas9	positive selection	3097154
75398951	75398974	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.12467659509029422	[3,3]	[3,2]	2	hSpCas9	positive selection	3097155
75398976	75398999	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.03601212251061023	[4,4]	[3,1]	0	hSpCas9	positive selection	3097156
75398976	75398999	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.03601212251061023	[4,4]	[3,1]	0	hSpCas9	positive selection	3097157
75398976	75398999	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.03601212251061023	[4,4]	[3,1]	0	hSpCas9	positive selection	3097158
75398976	75398999	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.03601212251061023	[4,4]	[3,1]	0	hSpCas9	positive selection	3097159
75399006	75399029	7	+	26780180	HT29	viability (Avana library 4 designs)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.036870543789652	[]	[]	0	hSpCas9	negative selection	3468144
75399006	75399029	7	+	26780180	HT29	viability (Avana library 4 designs)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.036870543789652	[]	[]	0	hSpCas9	negative selection	3468145
75398951	75398974	7	-	26780180	HT29	viability (Avana library 4 designs)	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.0882557572744168	[]	[]	0	hSpCas9	negative selection	3468146
75399275	75399298	7	+	26780180	HT29	viability (Avana library 4 designs)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	1.18951787163657	[]	[]	4	hSpCas9	negative selection	3468147
75399275	75399298	7	+	26780180	HT29	viability (Avana library 4 designs)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	1.18951787163657	[]	[]	4	hSpCas9	negative selection	3468148
75398975	75398998	7	+	26780180	HT29	viability (Avana library 4 designs)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	1.92051004303293	[]	[]	7	hSpCas9	negative selection	3468149
75398975	75398998	7	+	26780180	HT29	viability (Avana library 4 designs)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	1.92051004303293	[]	[]	7	hSpCas9	negative selection	3468150
75399006	75399029	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	3.10146767783026	[]	[]	5	hSpCas9	negative selection	3572664
75399006	75399029	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	3.10146767783026	[]	[]	5	hSpCas9	negative selection	3572665
75399006	75399029	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	4.32345614114991	[]	[]	7	hSpCas9	negative selection	3572666
75399006	75399029	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	4.32345614114991	[]	[]	7	hSpCas9	negative selection	3572667
75398951	75398974	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	5.72701339251101	[]	[]	9	hSpCas9	negative selection	3572668
75398975	75398998	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-3.91305360357513	[]	[]	-4	hSpCas9	negative selection	3572669
75398975	75398998	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-3.91305360357513	[]	[]	-4	hSpCas9	negative selection	3572670
75398975	75398998	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-8.04642421564735	[]	[]	-7	hSpCas9	negative selection	3572671
75398975	75398998	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-8.04642421564735	[]	[]	-7	hSpCas9	negative selection	3572672
75399275	75399298	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	1.82612469832425	[]	[]	2	hSpCas9	negative selection	3572673
75399275	75399298	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	1.82612469832425	[]	[]	2	hSpCas9	negative selection	3572674
75399275	75399298	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	-5.47241730374495	[]	[]	-5	hSpCas9	negative selection	3572675
75399275	75399298	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	-5.47241730374495	[]	[]	-5	hSpCas9	negative selection	3572676
75399053	75399076	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-5.28882614179644	[]	[]	-5	hSpCas9	negative selection	3572677
75399053	75399076	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-5.28882614179644	[]	[]	-5	hSpCas9	negative selection	3572678
75399053	75399076	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-0.267653922927806	[]	[]	0	hSpCas9	negative selection	3572679
75399053	75399076	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-0.267653922927806	[]	[]	0	hSpCas9	negative selection	3572680
75399006	75399029	7	+	26780180	A375	viability (Avana lentiGuide)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	-0.208229557711574	[]	[]	0	hSpCas9	negative selection	3681323
75399006	75399029	7	+	26780180	A375	viability (Avana lentiGuide)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	-0.208229557711574	[]	[]	0	hSpCas9	negative selection	3681324
75399006	75399029	7	+	26780180	A375	viability (Avana lentiGuide)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	2.09430478686481	[]	[]	2	hSpCas9	negative selection	3681325
75399006	75399029	7	+	26780180	A375	viability (Avana lentiGuide)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	2.09430478686481	[]	[]	2	hSpCas9	negative selection	3681326
75398951	75398974	7	-	26780180	A375	viability (Avana lentiGuide)	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-1.41743179341638	[]	[]	-2	hSpCas9	negative selection	3681327
75398975	75398998	7	+	26780180	A375	viability (Avana lentiGuide)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	3.62621566958561	[]	[]	3	hSpCas9	negative selection	3681328
75398975	75398998	7	+	26780180	A375	viability (Avana lentiGuide)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	3.62621566958561	[]	[]	3	hSpCas9	negative selection	3681329
75398975	75398998	7	+	26780180	A375	viability (Avana lentiGuide)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	7.97358179887562	[]	[]	6	hSpCas9	negative selection	3681330
75398975	75398998	7	+	26780180	A375	viability (Avana lentiGuide)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	7.97358179887562	[]	[]	6	hSpCas9	negative selection	3681331
75399275	75399298	7	+	26780180	A375	viability (Avana lentiGuide)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	11.5681156660576	[]	[]	7	hSpCas9	negative selection	3681332
75399275	75399298	7	+	26780180	A375	viability (Avana lentiGuide)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	11.5681156660576	[]	[]	7	hSpCas9	negative selection	3681333
75399275	75399298	7	+	26780180	A375	viability (Avana lentiGuide)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	8.90627827324154	[]	[]	6	hSpCas9	negative selection	3681334
75399275	75399298	7	+	26780180	A375	viability (Avana lentiGuide)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	8.90627827324154	[]	[]	6	hSpCas9	negative selection	3681335
75399053	75399076	7	+	26780180	A375	viability (Avana lentiGuide)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	5.40368795889751	[]	[]	5	hSpCas9	negative selection	3681336
75399053	75399076	7	+	26780180	A375	viability (Avana lentiGuide)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	5.40368795889751	[]	[]	5	hSpCas9	negative selection	3681337
75399053	75399076	7	+	26780180	A375	viability (Avana lentiGuide)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	8.53776548423865	[]	[]	6	hSpCas9	negative selection	3681338
75399053	75399076	7	+	26780180	A375	viability (Avana lentiGuide)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	8.53776548423865	[]	[]	6	hSpCas9	negative selection	3681339
75399006	75399029	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.09665217502475977	[5]	[6,5]	2	hSpCas9	positive selection	3789930
75399006	75399029	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.09665217502475977	[5]	[6,4]	2	hSpCas9	positive selection	3789931
75398951	75398974	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.03101181803720819	[4]	[5,4]	0	hSpCas9	positive selection	3789932
75398975	75398998	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.03101181803720819	[5]	[4,4]	0	hSpCas9	positive selection	3789933
75398975	75398998	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.03101181803720819	[4]	[4,3]	0	hSpCas9	positive selection	3789934
75399006	75399029	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.09665217502475977	[5]	[6,5]	2	hSpCas9	positive selection	3789935
75399006	75399029	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	0.09665217502475977	[5]	[6,4]	2	hSpCas9	positive selection	3789936
75398975	75398998	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.08187570507618291	[5]	[4,4]	-1	hSpCas9	positive selection	3789937
75399275	75399298	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	-0.08187570507618291	[4]	[3,4]	-1	hSpCas9	positive selection	3789938
75398975	75398998	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.08187570507618291	[4]	[4,3]	-1	hSpCas9	positive selection	3789939
75399275	75399298	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	-0.08187570507618291	[3]	[3,2]	-1	hSpCas9	positive selection	3789940
75399275	75399298	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	-0.04246613194173601	[4]	[3,4]	0	hSpCas9	positive selection	3789941
75399275	75399298	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	-0.04246613194173601	[3]	[3,2]	0	hSpCas9	positive selection	3789942
75399053	75399076	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-0.04246613194173601	[5]	[5,3]	0	hSpCas9	positive selection	3789943
75399053	75399076	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-0.04246613194173601	[4]	[4,3]	0	hSpCas9	positive selection	3789944
75399053	75399076	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-0.13370388928036853	[5]	[5,3]	-2	hSpCas9	positive selection	3789945
75399053	75399076	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-0.13370388928036853	[4]	[4,3]	-2	hSpCas9	positive selection	3789946
75399006	75399029	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	-0.043811844129669535	[5]	[4,3]	0	hSpCas9	positive selection	3898537
75399006	75399029	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	-0.043811844129669535	[5]	[5,2]	0	hSpCas9	positive selection	3898538
75398951	75398974	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.4821780975416201	[5]	[4,1]	-6	hSpCas9	positive selection	3898539
75398975	75398998	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.4821780975416201	[5]	[3,2]	-6	hSpCas9	positive selection	3898540
75398975	75398998	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.4821780975416201	[5]	[2,3]	-6	hSpCas9	positive selection	3898541
75399006	75399029	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	-0.043811844129669535	[5]	[4,3]	0	hSpCas9	positive selection	3898542
75399006	75399029	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTCCCTAATGCTACAGTGCGG	TRIM73	ENSG00000178809	-0.043811844129669535	[5]	[5,2]	0	hSpCas9	positive selection	3898543
75398975	75398998	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.5121113159864554	[5]	[3,2]	-6	hSpCas9	positive selection	3898544
75399275	75399298	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	-0.5121113159864554	[5]	[3,3]	-6	hSpCas9	positive selection	3898545
75398975	75398998	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGTGTCCCATCTGCCTGGAGG	TRIM73	ENSG00000178809	-0.5121113159864554	[5]	[2,3]	-6	hSpCas9	positive selection	3898546
75399275	75399298	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	-0.5121113159864554	[5]	[3,2]	-6	hSpCas9	positive selection	3898547
75399275	75399298	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	-0.4134937987200256	[5]	[3,3]	-5	hSpCas9	positive selection	3898548
75399275	75399298	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCTCCCACCAACACCACCCGG	TRIM73	ENSG00000178809	-0.4134937987200256	[5]	[3,2]	-5	hSpCas9	positive selection	3898549
75399053	75399076	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-0.4134937987200256	[7]	[6,5]	-5	hSpCas9	positive selection	3898550
75399053	75399076	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-0.4134937987200256	[6]	[1,3]	-5	hSpCas9	positive selection	3898551
75399053	75399076	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-0.316590750199929	[7]	[6,5]	-4	hSpCas9	positive selection	3898552
75399053	75399076	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTTCCCTGTCCTACCACCTGG	TRIM73	ENSG00000178809	-0.316590750199929	[6]	[1,3]	-4	hSpCas9	positive selection	3898553
75404840	75404863	7	+	26780180	A375	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	1.60337723195626	[]	[]	8	hSpCas9	negative selection	4007863
75403659	75403682	7	+	26780180	A375	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	1.16090571286866	[]	[]	6	hSpCas9	negative selection	4007864
75403659	75403682	7	+	26780180	A375	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	1.16090571286866	[]	[]	6	hSpCas9	negative selection	4007865
75398951	75398974	7	-	26780180	A375	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	1.06538051655132	[]	[]	5	hSpCas9	negative selection	4007866
75404840	75404863	7	+	26780180	HT29	viability (GeCKOv2 library)	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	1.52353354290012	[]	[]	7	hSpCas9	negative selection	4115829
75403659	75403682	7	+	26780180	HT29	viability (GeCKOv2 library)	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	1.80977669106815	[]	[]	8	hSpCas9	negative selection	4115830
75403659	75403682	7	+	26780180	HT29	viability (GeCKOv2 library)	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	1.80977669106815	[]	[]	8	hSpCas9	negative selection	4115831
75398951	75398974	7	-	26780180	HT29	viability (GeCKOv2 library)	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.470471561428421	[]	[]	1	hSpCas9	negative selection	4115832
75398951	75398974	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.0749077779498811	[3]	[3,1]	1	hSpCas9	positive selection	4305227
75398924	75398947	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.5333234116951686	[2]	[0,0]	-8	hSpCas9	positive selection	4305229
75399313	75399336	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	0.07608353423953429	[1]	[1,0]	1	hSpCas9	positive selection	4305230
75403659	75403682	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.07558783223496546	[2]	[2,1]	-1	hSpCas9	positive selection	4305231
75403659	75403682	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.07558783223496546	[2]	[2,1]	-1	hSpCas9	positive selection	4369475
75404840	75404863	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.7839896954760065	[2]	[1,0]	-9	hSpCas9	positive selection	4369479
75399025	75399047	7	+	27760321	OCIAML3	viability	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	-0.4954731769654772	[1970,1644]	[806,1248]	-5	hSpCas9	negative selection	4450172
75399071	75399093	7	-	27760321	OCIAML3	viability	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	-0.29651293778302	[2124,1601]	[1185,1164]	-3	hSpCas9	negative selection	4450173
75399190	75399212	7	-	27760321	OCIAML3	viability	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-1.2882333402832662	[1218,1009]	[363,343]	-8	hSpCas9	negative selection	4450174
75399025	75399047	7	+	27760321	OCIAML2	viability	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	-0.6127759118813514	[1970,1644]	[939,968]	-6	hSpCas9	negative selection	4533635
75399071	75399093	7	-	27760321	OCIAML2	viability	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	-0.09095607925624227	[2124,1601]	[1108,1791]	-1	hSpCas9	negative selection	4533636
75399190	75399212	7	-	27760321	OCIAML2	viability	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-1.062003641435625	[1218,1009]	[419,442]	-7	hSpCas9	negative selection	4533637
75399025	75399047	7	+	27760321	MV411	viability	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	-0.06091110498516028	[1970,1644]	[979,1377]	0	hSpCas9	negative selection	4617098
75399071	75399093	7	-	27760321	MV411	viability	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	0.3718332787661116	[2124,1601]	[1524,1657]	2	hSpCas9	negative selection	4617099
75399190	75399212	7	-	27760321	MV411	viability	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-0.42203769381815226	[1218,1009]	[428,722]	-3	hSpCas9	negative selection	4617100
75399025	75399047	7	+	27760321	HL60	viability	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	-0.6978201104225372	[1970,1644]	[832,984]	-6	hSpCas9	negative selection	4700561
75399071	75399093	7	-	27760321	HL60	viability	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	-0.24298892403182437	[2124,1601]	[1331,1215]	-3	hSpCas9	negative selection	4700562
75399190	75399212	7	-	27760321	HL60	viability	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-0.35117808270688056	[1218,1009]	[811,602]	-4	hSpCas9	negative selection	4700563
75399025	75399047	7	+	27760321	HT1080	viability	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	-0.5212548941543134	[1644,1283]	[511,290]	-2	hSpCas9	negative selection	4784024
75399071	75399093	7	-	27760321	HT1080	viability	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	-0.572490771032149	[1601,1249]	[381,381]	-3	hSpCas9	negative selection	4784025
75399190	75399212	7	-	27760321	HT1080	viability	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-1.6671344871299085	[1009,787]	[149,71]	-5	hSpCas9	negative selection	4784026
75399025	75399047	7	+	27760321	HT29	viability after 7 days	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	0.2775287749838431	[1644,1283]	[2731,2057,2122]	4	hSpCas9	negative selection	4867487
75399071	75399093	7	-	27760321	HT29	viability after 7 days	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	0.38224921833980186	[1601,1249]	[2257,2162,2714]	6	hSpCas9	negative selection	4867488
75399190	75399212	7	-	27760321	HT29	viability after 7 days	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	0.005852713196590198	[1009,787]	[1321,1276,911]	0	hSpCas9	negative selection	4867489
75399025	75399047	7	+	27760321	HT29	viability after 25 days	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	0.13262543974672703	[1644,1283]	[1848,1487,2201]	1	hSpCas9	negative selection	4950950
75399071	75399093	7	-	27760321	HT29	viability after 25 days	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	-0.0006043244807092396	[1601,1249]	[1468,1412,2056]	0	hSpCas9	negative selection	4950951
75399190	75399212	7	-	27760321	HT29	viability after 25 days	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-0.6383789170954958	[1009,787]	[531,666,802]	-5	hSpCas9	negative selection	4950952
75399025	75399047	7	+	27760321	HT29	viability after 22 days	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	0.24372898864508397	[1644,1283]	[2133,2014,1859]	2	hSpCas9	negative selection	5034413
75399071	75399093	7	-	27760321	HT29	viability after 22 days	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	0.11999652022323404	[1601,1249]	[2061,1414,1890]	1	hSpCas9	negative selection	5034414
75399190	75399212	7	-	27760321	HT29	viability after 22 days	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-0.7189485577537649	[1009,787]	[375,586,940]	-6	hSpCas9	negative selection	5034415
75399025	75399047	7	+	27760321	HT29	viability after 19 days	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	0.22510341623051344	[1644,1283]	[2231,1532,2128]	2	hSpCas9	negative selection	5117876
75399071	75399093	7	-	27760321	HT29	viability after 19 days	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	0.26832927117211836	[1601,1249]	[1763,1461,2618]	2	hSpCas9	negative selection	5117877
75399190	75399212	7	-	27760321	HT29	viability after 19 days	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-0.6838537855390058	[1009,787]	[754,652,527]	-5	hSpCas9	negative selection	5117878
75399025	75399047	7	+	27760321	HT29	viability after 16 days	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	0.44217406273711113	[1644,1283]	[2360,1759,2581]	5	hSpCas9	negative selection	5201339
75399071	75399093	7	-	27760321	HT29	viability after 16 days	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	0.05388001094225303	[1601,1249]	[1558,1535,1866]	0	hSpCas9	negative selection	5201340
75399190	75399212	7	-	27760321	HT29	viability after 16 days	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-0.982729992592659	[1009,787]	[466,462,593]	-7	hSpCas9	negative selection	5201341
75399025	75399047	7	+	27760321	HT29	viability after 13 days	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	0.1443337997102736	[1644,1283]	[2035,1828,1773]	1	hSpCas9	negative selection	5284802
75399071	75399093	7	-	27760321	HT29	viability after 13 days	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	0.23094017819234103	[1601,1249]	[2373,1421,2021]	3	hSpCas9	negative selection	5284803
75399190	75399212	7	-	27760321	HT29	viability after 13 days	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-0.603429439140304	[1009,787]	[632,785,642]	-6	hSpCas9	negative selection	5284804
75399025	75399047	7	+	27760321	HT29	viability after 10 days	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	0.18717784746315402	[1644,1283]	[2400,1995,1850]	2	hSpCas9	negative selection	5368265
75399071	75399093	7	-	27760321	HT29	viability after 10 days	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	0.06222594710575824	[1601,1249]	[1842,1397,2311]	0	hSpCas9	negative selection	5368266
75399190	75399212	7	-	27760321	HT29	viability after 10 days	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-0.4749703600688713	[1009,787]	[864,970,595]	-5	hSpCas9	negative selection	5368267
75399025	75399047	7	+	27760321	MOLM13	viability	GCGGCCACTCCTACTGCAAGGG	TRIM73	ENSG00000178809	-0.7931622402413785	[1970,1644]	[609,565]	-5	hSpCas9	negative selection	5451728
75399071	75399093	7	-	27760321	MOLM13	viability	GCAGCGCACCTTGGTGTCCAGG	TRIM73	ENSG00000178809	-0.15661129511452687	[2124,1601]	[888,974]	-1	hSpCas9	negative selection	5451729
75399190	75399212	7	-	27760321	MOLM13	viability	CGGTGGTGCACGCAGACCTTGG	TRIM73	ENSG00000178809	-0.4560955096776034	[1218,1009]	[249,631]	-3	hSpCas9	negative selection	5451730
75395638	75395661	7	+	27661255	K562	viability	GGGGCATGTGCGGGAGCGCCAGG	TRIM73	ENSG00000178809	0.08343921468849858	[2147,2388]	[2040,1809]	3	dCas9-KRAB	negative selection	5519833
75395665	75395688	7	+	27661255	K562	viability	GCATGTAACCAGAGCGTGCGGGG	TRIM73	ENSG00000178809	0.19988536278298658	[608,550]	[605,470]	7	dCas9-KRAB	negative selection	5519835
75395686	75395709	7	+	27661255	K562	viability	GGCATGATGGGGCACGGACATGG	TRIM73	ENSG00000178809	0.1502204806763061	[1140,1367]	[1149,1072]	5	dCas9-KRAB	negative selection	5519837
75398276	75398299	7	+	27661255	K562	viability	GGGCTCTCGCTGGGGGCTTCTGG	TRIM73	ENSG00000178809	-0.1395416131867726	[1331,1248]	[1005,877]	-5	dCas9-KRAB	negative selection	5519840
75398331	75398354	7	+	27661255	K562	viability	GGGGAGCAGGTGGGAGATCAGGG	TRIM73	ENSG00000178809	-0.1167937974822238	[824,863]	[626,616]	-4	dCas9-KRAB	negative selection	5519841
75398950	75398973	7	+	27661255	K562	viability	GCCTGCTGGAGCTGGAGGACCGG	TRIM73	ENSG00000178809	-0.015198979915273358	[637,551]	[504,442]	0	dCas9-KRAB	negative selection	5519844
75398159	75398182	7	-	27661255	K562	viability	GCAGGCACAGAGTCAGAAGTGGG	TRIM73	ENSG00000178809	0.09613689526032465	[1436,1569]	[1420,1162]	3	dCas9-KRAB	negative selection	5519848
75398990	75399013	7	-	27661255	K562	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	0.15343541575638375	[530,531]	[489,456]	5	dCas9-KRAB	negative selection	5519850
75399050	75399073	7	-	27661255	K562	viability	GGTGGTAGGACAGGGAAACCAGG	TRIM73	ENSG00000178809	0.4226503863206489	[696,835]	[817,817]	9	dCas9-KRAB	negative selection	5519852
75399260	75399283	7	-	27661255	K562	viability	GGGAGCCCAGCAGACCGCAGAGG	TRIM73	ENSG00000178809	0.043147303045400265	[1322,1264]	[1249,908]	1	dCas9-KRAB	negative selection	5519855
75398159	75398182	7	-	27661255	K562	viability	GCAGGCACAGAGTCAGAAGTGGG	TRIM73	ENSG00000178809	0.09613689526032465	[1436,1569]	[1420,1162]	3	dCas9-KRAB	negative selection	5519856
75398276	75398299	7	+	27661255	K562	viability	GGGCTCTCGCTGGGGGCTTCTGG	TRIM73	ENSG00000178809	-0.1395416131867726	[1331,1248]	[1005,877]	-5	dCas9-KRAB	negative selection	5519859
75395686	75395709	7	+	27661255	K562	viability	GGCATGATGGGGCACGGACATGG	TRIM73	ENSG00000178809	0.1502204806763061	[1140,1367]	[1149,1072]	5	dCas9-KRAB	negative selection	5519861
75395665	75395688	7	+	27661255	K562	viability	GCATGTAACCAGAGCGTGCGGGG	TRIM73	ENSG00000178809	0.19988536278298658	[608,550]	[605,470]	7	dCas9-KRAB	negative selection	5519863
75395638	75395661	7	+	27661255	K562	viability	GGGGCATGTGCGGGAGCGCCAGG	TRIM73	ENSG00000178809	0.08343921468849858	[2147,2388]	[2040,1809]	3	dCas9-KRAB	negative selection	5519866
75398951	75398974	7	-	27260156	BXPC3	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.2459376522403376	[506]	[558,698,621,633]	5	hSpCas9	negative selection	5577687
75398924	75398947	7	+	27260156	BXPC3	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.4693583108817523	[238]	[92,184,212,247]	-8	hSpCas9	negative selection	5577689
75399313	75399336	7	-	27260156	BXPC3	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.5326622490300892	[146]	[101,67,116,144]	-8	hSpCas9	negative selection	5577690
75403659	75403682	7	+	27260156	BXPC3	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.23514602355658304	[439]	[256,417,409,502]	-5	hSpCas9	negative selection	5577691
75403659	75403682	7	+	27260156	BXPC3	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.23514602355658304	[439]	[256,417,409,502]	-5	hSpCas9	negative selection	5641935
75404840	75404863	7	+	27260156	BXPC3	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.5691449108911815	[420]	[237,302,318,335]	-8	hSpCas9	negative selection	5641939
75398951	75398974	7	-	27260156	A673	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.28272509025767345	[506]	[857,723,660,731]	6	hSpCas9	negative selection	5698938
75398924	75398947	7	+	27260156	A673	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	0.13020965483657598	[238]	[386,290,317,265]	3	hSpCas9	negative selection	5698940
75399313	75399336	7	-	27260156	A673	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.20596165693198265	[146]	[160,148,132,170]	-5	hSpCas9	negative selection	5698941
75403659	75403682	7	+	27260156	A673	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.14964665924549614	[439]	[465,470,517,445]	-4	hSpCas9	negative selection	5698942
75403659	75403682	7	+	27260156	A673	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.14964665924549614	[439]	[465,470,517,445]	-4	hSpCas9	negative selection	5763186
75404840	75404863	7	+	27260156	A673	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.4149840940066906	[420]	[422,312,426,357]	-7	hSpCas9	negative selection	5763190
75398951	75398974	7	-	27260156	A375	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.3861059126659891	[506]	[727,866,808,708]	5	hSpCas9	negative selection	5820189
75398924	75398947	7	+	27260156	A375	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.5974350577951426	[238]	[183,77,243,212]	-7	hSpCas9	negative selection	5820191
75399313	75399336	7	-	27260156	A375	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.3108323727106004	[146]	[102,189,155,113]	-4	hSpCas9	negative selection	5820192
75403659	75403682	7	+	27260156	A375	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.10464863808166507	[439]	[664,315,523,393]	-1	hSpCas9	negative selection	5820193
75403659	75403682	7	+	27260156	A375	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.10464863808166507	[439]	[664,315,523,393]	-1	hSpCas9	negative selection	5884437
75404840	75404863	7	+	27260156	A375	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.7344724667322822	[420]	[226,299,384,271]	-7	hSpCas9	negative selection	5884441
75398951	75398974	7	-	27260156	COLO741	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.33157035800829454	[506]	[850,826,771]	7	hSpCas9	negative selection	5941440
75398924	75398947	7	+	27260156	COLO741	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.1587769583223213	[238]	[250,360,210]	-3	hSpCas9	negative selection	5941442
75399313	75399336	7	-	27260156	COLO741	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.27623372486936093	[146]	[111,216,133]	-5	hSpCas9	negative selection	5941443
75403659	75403682	7	+	27260156	COLO741	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.039320800882506814	[439]	[814,323,609]	0	hSpCas9	negative selection	5941444
75403659	75403682	7	+	27260156	COLO741	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.039320800882506814	[439]	[814,323,609]	0	hSpCas9	negative selection	6005688
75404840	75404863	7	+	27260156	COLO741	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.7474214787289208	[420]	[448,282,244]	-9	hSpCas9	negative selection	6005692
75398951	75398974	7	-	27260156	CAL120	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.5597946129763816	[506]	[1073,904,833]	8	hSpCas9	negative selection	6062691
75398924	75398947	7	+	27260156	CAL120	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.007437898573947166	[238]	[203,446,223]	0	hSpCas9	negative selection	6062693
75399313	75399336	7	-	27260156	CAL120	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	0.507805433114958	[146]	[250,221,304]	7	hSpCas9	negative selection	6062694
75403659	75403682	7	+	27260156	CAL120	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.332073451846182	[439]	[583,357,385]	-5	hSpCas9	negative selection	6062695
75403659	75403682	7	+	27260156	CAL120	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.332073451846182	[439]	[583,357,385]	-5	hSpCas9	negative selection	6126939
75404840	75404863	7	+	27260156	CAL120	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.07254421842022829	[420]	[589,576,343]	-1	hSpCas9	negative selection	6126943
75398951	75398974	7	-	27260156	CADOES1	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.4688966289539633	[506]	[648,564,726,669]	7	hSpCas9	negative selection	6183942
75398924	75398947	7	+	27260156	CADOES1	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	0.19112843796137546	[238]	[318,270,246,174]	3	hSpCas9	negative selection	6183944
75399313	75399336	7	-	27260156	CADOES1	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-1.0069433464941797	[146]	[69,32,101,66]	-9	hSpCas9	negative selection	6183945
75403659	75403682	7	+	27260156	CADOES1	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.095805595708654	[439]	[427,419,470,429]	1	hSpCas9	negative selection	6183946
75403659	75403682	7	+	27260156	CADOES1	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.095805595708654	[439]	[427,419,470,429]	1	hSpCas9	negative selection	6248190
75404840	75404863	7	+	27260156	CADOES1	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.525334460143456	[420]	[276,213,351,243]	-7	hSpCas9	negative selection	6248194
75398951	75398974	7	-	27260156	EWS502	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.2812262403002331	[506]	[518,591,663,866]	5	hSpCas9	negative selection	6305193
75398924	75398947	7	+	27260156	EWS502	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	0.061852529876506246	[238]	[366,197,303,170]	1	hSpCas9	negative selection	6305195
75399313	75399336	7	-	27260156	EWS502	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.2868507677630021	[146]	[68,103,143,206]	-5	hSpCas9	negative selection	6305196
75403659	75403682	7	+	27260156	EWS502	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.20312432498655433	[439]	[562,643,571,343]	3	hSpCas9	negative selection	6305197
75403659	75403682	7	+	27260156	EWS502	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.20312432498655433	[439]	[562,643,571,343]	3	hSpCas9	negative selection	6369441
75404840	75404863	7	+	27260156	EWS502	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.8403870939675682	[420]	[177,307,244,271]	-8	hSpCas9	negative selection	6369445
75398951	75398974	7	-	27260156	EW8	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.39107109099467324	[506]	[622,582,553,400]	7	hSpCas9	negative selection	6426444
75398924	75398947	7	+	27260156	EW8	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	0.34213048300280213	[238]	[248,262,172,308]	6	hSpCas9	negative selection	6426446
75399313	75399336	7	-	27260156	EW8	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	0.005515276279206782	[146]	[125,77,133,137]	0	hSpCas9	negative selection	6426447
75403659	75403682	7	+	27260156	EW8	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.273146707427427	[439]	[616,425,336,378]	5	hSpCas9	negative selection	6426448
75403659	75403682	7	+	27260156	EW8	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.273146707427427	[439]	[616,425,336,378]	5	hSpCas9	negative selection	6490692
75404840	75404863	7	+	27260156	EW8	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.5133485092546011	[420]	[300,290,171,209]	-7	hSpCas9	negative selection	6490696
75398951	75398974	7	-	27260156	CORL105	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.014271766996410015	[506]	[581,431,807,565]	0	hSpCas9	negative selection	6547695
75398924	75398947	7	+	27260156	CORL105	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.0025394071180186994	[238]	[286,332,306,193]	0	hSpCas9	negative selection	6547697
75399313	75399336	7	-	27260156	CORL105	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.2767880519199606	[146]	[135,132,47,235]	-5	hSpCas9	negative selection	6547698
75403659	75403682	7	+	27260156	CORL105	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.003214445045433542	[439]	[316,504,843,434]	0	hSpCas9	negative selection	6547699
75403659	75403682	7	+	27260156	CORL105	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.003214445045433542	[439]	[316,504,843,434]	0	hSpCas9	negative selection	6611943
75404840	75404863	7	+	27260156	CORL105	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.8014464712591294	[420]	[264,225,474,195]	-8	hSpCas9	negative selection	6611947
75398951	75398974	7	-	27260156	HS294T	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.041224109104693984	[506]	[131,274,198,204]	0	hSpCas9	negative selection	6668946
75398924	75398947	7	+	27260156	HS294T	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	0.07297698998172808	[238]	[56,83,58,211]	1	hSpCas9	negative selection	6668948
75399313	75399336	7	-	27260156	HS294T	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.3507979694360115	[146]	[15,77,39,45]	-5	hSpCas9	negative selection	6668949
75403659	75403682	7	+	27260156	HS294T	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.09113232234820963	[439]	[164,101,151,232]	-1	hSpCas9	negative selection	6668950
75403659	75403682	7	+	27260156	HS294T	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.09113232234820963	[439]	[164,101,151,232]	-1	hSpCas9	negative selection	6733194
75404840	75404863	7	+	27260156	HS294T	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.949107277238012	[420]	[77,89,91,75]	-8	hSpCas9	negative selection	6733198
75398951	75398974	7	-	27260156	HCC44	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.15470764147800858	[506]	[889,548,582,554]	2	hSpCas9	negative selection	6790197
75398924	75398947	7	+	27260156	HCC44	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.4233415565444607	[238]	[143,198,286,184]	-6	hSpCas9	negative selection	6790199
75399313	75399336	7	-	27260156	HCC44	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.4528564521697671	[146]	[50,136,182,115]	-6	hSpCas9	negative selection	6790200
75403659	75403682	7	+	27260156	HCC44	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.029004395342013087	[439]	[570,370,610,440]	0	hSpCas9	negative selection	6790201
75403659	75403682	7	+	27260156	HCC44	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.029004395342013087	[439]	[570,370,610,440]	0	hSpCas9	negative selection	6854445
75404840	75404863	7	+	27260156	HCC44	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.4669909362598948	[420]	[490,199,413,316]	-6	hSpCas9	negative selection	6854449
75398951	75398974	7	-	27260156	G402	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.5046578653042402	[506]	[1093,1082,651,728]	6	hSpCas9	negative selection	6911448
75398924	75398947	7	+	27260156	G402	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	0.1085556817885659	[238]	[170,595,337,154]	1	hSpCas9	negative selection	6911450
75399313	75399336	7	-	27260156	G402	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-1.8160957835590303	[146]	[4,122,40,32]	-9	hSpCas9	negative selection	6911451
75403659	75403682	7	+	27260156	G402	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.18871364971533566	[439]	[371,565,349,1095]	2	hSpCas9	negative selection	6911452
75403659	75403682	7	+	27260156	G402	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.18871364971533566	[439]	[371,565,349,1095]	2	hSpCas9	negative selection	6975696
75404840	75404863	7	+	27260156	G402	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-1.1679237114282623	[420]	[233,440,91,162]	-8	hSpCas9	negative selection	6975700
75398951	75398974	7	-	27260156	L33	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.08547307126328998	[506]	[506,196,404,520]	2	hSpCas9	negative selection	7032699
75398924	75398947	7	+	27260156	L33	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.3638639653672071	[238]	[223,84,100,149]	-7	hSpCas9	negative selection	7032701
75399313	75399336	7	-	27260156	L33	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.2555113197062229	[146]	[172,56,66,72]	-5	hSpCas9	negative selection	7032702
75403659	75403682	7	+	27260156	L33	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.09524144642126907	[439]	[385,224,237,566]	2	hSpCas9	negative selection	7032703
75403659	75403682	7	+	27260156	L33	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.09524144642126907	[439]	[385,224,237,566]	2	hSpCas9	negative selection	7096947
75404840	75404863	7	+	27260156	L33	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.6617673016121153	[420]	[332,65,190,264]	-9	hSpCas9	negative selection	7096951
75398951	75398974	7	-	27260156	K562	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.019670143104236593	[506]	[498,483,487,366]	0	hSpCas9	negative selection	7153950
75398924	75398947	7	+	27260156	K562	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-1.0538506205552425	[238]	[36,98,204,65]	-8	hSpCas9	negative selection	7153952
75399313	75399336	7	-	27260156	K562	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.2601615867774365	[146]	[173,78,161,32]	-3	hSpCas9	negative selection	7153953
75403659	75403682	7	+	27260156	K562	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.1627679422385824	[439]	[443,371,568,366]	2	hSpCas9	negative selection	7153954
75403659	75403682	7	+	27260156	K562	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.1627679422385824	[439]	[443,371,568,366]	2	hSpCas9	negative selection	7218198
75404840	75404863	7	+	27260156	K562	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-1.622413589408861	[420]	[176,124,135,58]	-9	hSpCas9	negative selection	7218202
75398951	75398974	7	-	27260156	HT29	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.23614625682628748	[506]	[778,758,844,544]	4	hSpCas9	negative selection	7275201
75398924	75398947	7	+	27260156	HT29	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.20501505781743234	[238]	[265,285,319,150]	-4	hSpCas9	negative selection	7275203
75399313	75399336	7	-	27260156	HT29	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.37385468790945175	[146]	[46,159,195,141]	-6	hSpCas9	negative selection	7275204
75403659	75403682	7	+	27260156	HT29	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.046427595635646704	[439]	[540,501,602,432]	-1	hSpCas9	negative selection	7275205
75403659	75403682	7	+	27260156	HT29	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.046427595635646704	[439]	[540,501,602,432]	-1	hSpCas9	negative selection	7339449
75404840	75404863	7	+	27260156	HT29	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-1.0165945777855674	[420]	[248,202,251,295]	-8	hSpCas9	negative selection	7339453
75398951	75398974	7	-	27260156	MHHES1	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.31556720639497793	[506]	[771,637,902,551]	6	hSpCas9	negative selection	7396452
75398924	75398947	7	+	27260156	MHHES1	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.6528747606805752	[238]	[201,216,89,177]	-8	hSpCas9	negative selection	7396454
75399313	75399336	7	-	27260156	MHHES1	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.021797840118576772	[146]	[192,248,99,126]	0	hSpCas9	negative selection	7396455
75403659	75403682	7	+	27260156	MHHES1	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.29499395459202965	[439]	[504,340,448,333]	-5	hSpCas9	negative selection	7396456
75403659	75403682	7	+	27260156	MHHES1	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.29499395459202965	[439]	[504,340,448,333]	-5	hSpCas9	negative selection	7460700
75404840	75404863	7	+	27260156	MHHES1	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.8177124189024623	[420]	[290,288,183,301]	-9	hSpCas9	negative selection	7460704
75398951	75398974	7	-	27260156	MEWO	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.2614461130465954	[506]	[656,509,555]	5	hSpCas9	negative selection	7517703
75398924	75398947	7	+	27260156	MEWO	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	0.18414506998856095	[238]	[422,212,158]	4	hSpCas9	negative selection	7517705
75399313	75399336	7	-	27260156	MEWO	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	0.5279597596257024	[146]	[146,180,256]	9	hSpCas9	negative selection	7517706
75403659	75403682	7	+	27260156	MEWO	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.1305923879249826	[439]	[681,381,332]	3	hSpCas9	negative selection	7517707
75403659	75403682	7	+	27260156	MEWO	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.1305923879249826	[439]	[681,381,332]	3	hSpCas9	negative selection	7581951
75404840	75404863	7	+	27260156	MEWO	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.369267130687794	[420]	[372,283,270]	-7	hSpCas9	negative selection	7581955
75398951	75398974	7	-	27260156	LNCAPCLONEFGC	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.42928911926639896	[506]	[586,542,564,775]	6	hSpCas9	negative selection	7638954
75398924	75398947	7	+	27260156	LNCAPCLONEFGC	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.19627473121647632	[238]	[167,166,238,190]	-3	hSpCas9	negative selection	7638956
75399313	75399336	7	-	27260156	LNCAPCLONEFGC	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.399382040041369	[146]	[126,78,176,32]	-6	hSpCas9	negative selection	7638957
75403659	75403682	7	+	27260156	LNCAPCLONEFGC	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.3543808151533982	[439]	[234,311,295,402]	-5	hSpCas9	negative selection	7638958
75403659	75403682	7	+	27260156	LNCAPCLONEFGC	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.3543808151533982	[439]	[234,311,295,402]	-5	hSpCas9	negative selection	7703202
75404840	75404863	7	+	27260156	LNCAPCLONEFGC	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-1.0542027851899791	[420]	[191,229,154,149]	-9	hSpCas9	negative selection	7703206
75398951	75398974	7	-	27260156	PANC0327	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.28057145361665087	[506]	[717,382,446,674]	4	hSpCas9	negative selection	7760205
75398924	75398947	7	+	27260156	PANC0327	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.04564969673672126	[238]	[548,71,108,137]	0	hSpCas9	negative selection	7760207
75399313	75399336	7	-	27260156	PANC0327	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.6392957639562384	[146]	[114,66,59,97]	-7	hSpCas9	negative selection	7760208
75403659	75403682	7	+	27260156	PANC0327	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.4664495396142413	[439]	[153,443,237,263]	-6	hSpCas9	negative selection	7760209
75403659	75403682	7	+	27260156	PANC0327	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.4664495396142413	[439]	[153,443,237,263]	-6	hSpCas9	negative selection	7824453
75404840	75404863	7	+	27260156	PANC0327	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.5426533877201416	[420]	[445,211,149,239]	-6	hSpCas9	negative selection	7824457
75398951	75398974	7	-	27260156	NCIH2009	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.12025637965779142	[506]	[740,522,709]	-2	hSpCas9	negative selection	7881456
75398924	75398947	7	+	27260156	NCIH2009	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.6036494714804597	[238]	[331,167,181]	-6	hSpCas9	negative selection	7881458
75399313	75399336	7	-	27260156	NCIH2009	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-1.7480113611008683	[146]	[112,37,42]	-9	hSpCas9	negative selection	7881459
75403659	75403682	7	+	27260156	NCIH2009	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.23143720913446197	[439]	[681,485,433]	-3	hSpCas9	negative selection	7881460
75403659	75403682	7	+	27260156	NCIH2009	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.23143720913446197	[439]	[681,485,433]	-3	hSpCas9	negative selection	7945704
75404840	75404863	7	+	27260156	NCIH2009	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-1.1027102157947013	[420]	[248,399,164]	-8	hSpCas9	negative selection	7945708
75398951	75398974	7	-	27260156	NCIH1373	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.1899853871284943	[506]	[520,462,335,181]	-2	hSpCas9	negative selection	8002707
75398924	75398947	7	+	27260156	NCIH1373	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.6676095864124734	[238]	[146,149,185,49]	-6	hSpCas9	negative selection	8002709
75399313	75399336	7	-	27260156	NCIH1373	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.8264765581647722	[146]	[42,69,54,53]	-7	hSpCas9	negative selection	8002710
75403659	75403682	7	+	27260156	NCIH1373	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.3272696249727128	[439]	[622,504,188,71]	-3	hSpCas9	negative selection	8002711
75403659	75403682	7	+	27260156	NCIH1373	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.3272696249727128	[439]	[622,504,188,71]	-3	hSpCas9	negative selection	8066955
75404840	75404863	7	+	27260156	NCIH1373	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-1.844936463093004	[420]	[68,88,124,63]	-9	hSpCas9	negative selection	8066959
75398951	75398974	7	-	27260156	PATU8902	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.8085370758626638	[506]	[1475,1972,528,1128]	8	hSpCas9	negative selection	8123958
75398924	75398947	7	+	27260156	PATU8902	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.6068212790199248	[238]	[330,152,243,124]	-5	hSpCas9	negative selection	8123960
75399313	75399336	7	-	27260156	PATU8902	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.3490518959215132	[146]	[89,185,143,235]	-3	hSpCas9	negative selection	8123961
75403659	75403682	7	+	27260156	PATU8902	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.1333831312600706	[439]	[823,497,844,440]	1	hSpCas9	negative selection	8123962
75403659	75403682	7	+	27260156	PATU8902	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.1333831312600706	[439]	[823,497,844,440]	1	hSpCas9	negative selection	8188206
75404840	75404863	7	+	27260156	PATU8902	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-1.3420674957990304	[420]	[149,422,128,251]	-8	hSpCas9	negative selection	8188210
75398951	75398974	7	-	27260156	PANC1	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.0032919274445174923	[506]	[464,672,364,304]	0	hSpCas9	negative selection	8245209
75398924	75398947	7	+	27260156	PANC1	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.45305495278917407	[238]	[196,116,182,100]	-6	hSpCas9	negative selection	8245211
75399313	75399336	7	-	27260156	PANC1	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.4894833819674038	[146]	[61,134,80,89]	-6	hSpCas9	negative selection	8245212
75403659	75403682	7	+	27260156	PANC1	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.2237075176422743	[439]	[393,275,333,280]	-4	hSpCas9	negative selection	8245213
75403659	75403682	7	+	27260156	PANC1	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.2237075176422743	[439]	[393,275,333,280]	-4	hSpCas9	negative selection	8309457
75404840	75404863	7	+	27260156	PANC1	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-1.0990974857871636	[420]	[163,191,164,157]	-8	hSpCas9	negative selection	8309461
75398951	75398974	7	-	27260156	PANC0813	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.06642603522934298	[506]	[674,642,696,490]	1	hSpCas9	negative selection	8366460
75398924	75398947	7	+	27260156	PANC0813	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.5433848428370591	[238]	[190,182,252,145]	-7	hSpCas9	negative selection	8366462
75399313	75399336	7	-	27260156	PANC0813	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.4910675793729169	[146]	[238,51,107,103]	-6	hSpCas9	negative selection	8366463
75403659	75403682	7	+	27260156	PANC0813	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.07236960211950262	[439]	[655,546,360,419]	-1	hSpCas9	negative selection	8366464
75403659	75403682	7	+	27260156	PANC0813	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.07236960211950262	[439]	[655,546,360,419]	-1	hSpCas9	negative selection	8430708
75404840	75404863	7	+	27260156	PANC0813	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.9565252283227565	[420]	[446,176,204,209]	-8	hSpCas9	negative selection	8430712
75398951	75398974	7	-	27260156	RDES	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.3500725222189017	[506]	[631,709,907,730]	5	hSpCas9	negative selection	8487711
75398924	75398947	7	+	27260156	RDES	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.059892781005761675	[238]	[200,188,398,287]	-1	hSpCas9	negative selection	8487713
75399313	75399336	7	-	27260156	RDES	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	0.17933539515303965	[146]	[253,152,128,212]	3	hSpCas9	negative selection	8487714
75403659	75403682	7	+	27260156	RDES	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.016640906035549893	[439]	[332,534,587,578]	0	hSpCas9	negative selection	8487715
75403659	75403682	7	+	27260156	RDES	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.016640906035549893	[439]	[332,534,587,578]	0	hSpCas9	negative selection	8551959
75404840	75404863	7	+	27260156	RDES	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.5658463152519193	[420]	[336,366,363,204]	-7	hSpCas9	negative selection	8551963
75398951	75398974	7	-	27260156	PC3	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.4938803399918326	[506]	[410,637,1109,923]	8	hSpCas9	negative selection	8608962
75398924	75398947	7	+	27260156	PC3	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	0.17725795221410012	[238]	[203,211,296,380]	4	hSpCas9	negative selection	8608964
75399313	75399336	7	-	27260156	PC3	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	0.08679030033100266	[146]	[121,68,197,255]	2	hSpCas9	negative selection	8608965
75403659	75403682	7	+	27260156	PC3	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.02149735062512341	[439]	[264,380,886,406]	0	hSpCas9	negative selection	8608966
75403659	75403682	7	+	27260156	PC3	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.02149735062512341	[439]	[264,380,886,406]	0	hSpCas9	negative selection	8673210
75404840	75404863	7	+	27260156	PC3	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.11260437823857183	[420]	[280,370,495,453]	-3	hSpCas9	negative selection	8673214
75398951	75398974	7	-	27260156	PATU8988T	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.1667134679756208	[506]	[615,680,439,469]	3	hSpCas9	negative selection	8730213
75398924	75398947	7	+	27260156	PATU8988T	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	0.3340194917847067	[238]	[171,361,425,201]	6	hSpCas9	negative selection	8730215
75399313	75399336	7	-	27260156	PATU8988T	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	0.2630526168172591	[146]	[123,236,109,221]	4	hSpCas9	negative selection	8730216
75403659	75403682	7	+	27260156	PATU8988T	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.3911442523844783	[439]	[273,359,310,357]	-6	hSpCas9	negative selection	8730217
75403659	75403682	7	+	27260156	PATU8988T	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.3911442523844783	[439]	[273,359,310,357]	-6	hSpCas9	negative selection	8794461
75404840	75404863	7	+	27260156	PATU8988T	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.4883457837290956	[420]	[263,417,221,266]	-7	hSpCas9	negative selection	8794465
75398951	75398974	7	-	27260156	T47D	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.33417907595818624	[506]	[681,755,775,762]	7	hSpCas9	negative selection	8851464
75398924	75398947	7	+	27260156	T47D	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.5347948094974639	[238]	[226,140,191,213]	-8	hSpCas9	negative selection	8851466
75399313	75399336	7	-	27260156	T47D	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.40028259238049957	[146]	[132,108,138,139]	-7	hSpCas9	negative selection	8851467
75403659	75403682	7	+	27260156	T47D	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.3899753494721691	[439]	[402,337,386,442]	-7	hSpCas9	negative selection	8851468
75403659	75403682	7	+	27260156	T47D	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.3899753494721691	[439]	[402,337,386,442]	-7	hSpCas9	negative selection	8915712
75404840	75404863	7	+	27260156	T47D	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.7284275418917256	[420]	[303,305,326,243]	-8	hSpCas9	negative selection	8915716
75398951	75398974	7	-	27260156	SU8686	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.1234446190224712	[506]	[394,526,646,657]	2	hSpCas9	negative selection	8972715
75398924	75398947	7	+	27260156	SU8686	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.24802859164485014	[238]	[121,277,158,241]	-4	hSpCas9	negative selection	8972717
75399313	75399336	7	-	27260156	SU8686	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.5063510856544511	[146]	[78,82,115,143]	-7	hSpCas9	negative selection	8972718
75403659	75403682	7	+	27260156	SU8686	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.29252981528303357	[439]	[304,238,364,568]	-5	hSpCas9	negative selection	8972719
75403659	75403682	7	+	27260156	SU8686	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.29252981528303357	[439]	[304,238,364,568]	-5	hSpCas9	negative selection	9036963
75404840	75404863	7	+	27260156	SU8686	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-1.0351251227866696	[420]	[126,171,211,336]	-8	hSpCas9	negative selection	9036967
75398951	75398974	7	-	27260156	SKES1	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.3767917478892107	[506]	[736,836,531,559]	7	hSpCas9	negative selection	9093966
75398924	75398947	7	+	27260156	SKES1	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.04443703363105955	[238]	[164,250,340,164]	-1	hSpCas9	negative selection	9093968
75399313	75399336	7	-	27260156	SKES1	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	0.0938295334492929	[146]	[173,127,141,176]	2	hSpCas9	negative selection	9093969
75403659	75403682	7	+	27260156	SKES1	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.03949290528917998	[439]	[608,377,409,419]	0	hSpCas9	negative selection	9093970
75403659	75403682	7	+	27260156	SKES1	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	0.03949290528917998	[439]	[608,377,409,419]	0	hSpCas9	negative selection	9158214
75404840	75404863	7	+	27260156	SKES1	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.48213923601686853	[420]	[225,363,361,249]	-8	hSpCas9	negative selection	9158218
75398951	75398974	7	-	27260156	TOV112D	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.39602876475729026	[506]	[632,870,633,582]	7	hSpCas9	negative selection	9215217
75398924	75398947	7	+	27260156	TOV112D	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	0.022660122144964268	[238]	[181,406,232,186]	0	hSpCas9	negative selection	9215219
75399313	75399336	7	-	27260156	TOV112D	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.20917627700928731	[146]	[110,190,75,144]	-4	hSpCas9	negative selection	9215220
75403659	75403682	7	+	27260156	TOV112D	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.06591570034778498	[439]	[511,391,364,414]	-1	hSpCas9	negative selection	9215221
75403659	75403682	7	+	27260156	TOV112D	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.06591570034778498	[439]	[511,391,364,414]	-1	hSpCas9	negative selection	9279465
75404840	75404863	7	+	27260156	TOV112D	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.39701014538156126	[420]	[330,253,397,282]	-7	hSpCas9	negative selection	9279469
75398951	75398974	7	-	27260156	TC71	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.1358140811480062	[506]	[381,650,667,695]	3	hSpCas9	negative selection	9336468
75398924	75398947	7	+	27260156	TC71	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.03919016314831114	[238]	[242,221,215,321]	-1	hSpCas9	negative selection	9336470
75399313	75399336	7	-	27260156	TC71	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.0031662463104324967	[146]	[259,99,141,122]	0	hSpCas9	negative selection	9336471
75403659	75403682	7	+	27260156	TC71	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.027782998006228105	[439]	[336,557,517,436]	0	hSpCas9	negative selection	9336472
75403659	75403682	7	+	27260156	TC71	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.027782998006228105	[439]	[336,557,517,436]	0	hSpCas9	negative selection	9400716
75404840	75404863	7	+	27260156	TC71	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.3085205567106202	[420]	[309,317,388,445]	-7	hSpCas9	negative selection	9400720
75398951	75398974	7	-	27260156	TC32	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.5822199369113892	[506]	[483,751,916,703]	8	hSpCas9	negative selection	9457719
75398924	75398947	7	+	27260156	TC32	viability	GTGAGTGTGGATGGCTTGGCAGG	TRIM73	ENSG00000178809	-0.054931227604237076	[238]	[199,99,243,368]	-1	hSpCas9	negative selection	9457721
75399313	75399336	7	-	27260156	TC32	viability	CACCTTCATGCGGCTGCAGACGG	TRIM73	ENSG00000178809	-0.09302992791385933	[146]	[109,109,165,140]	-2	hSpCas9	negative selection	9457722
75403659	75403682	7	+	27260156	TC32	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.058880025595744	[439]	[414,294,392,501]	-1	hSpCas9	negative selection	9457723
75403659	75403682	7	+	27260156	TC32	viability	CCTCTTCTCTGAGCTGAAGCAGG	TRIM73	ENSG00000178809	-0.058880025595744	[439]	[414,294,392,501]	-1	hSpCas9	negative selection	9521967
75404840	75404863	7	+	27260156	TC32	viability	ATGAGTCGGATGTCTTCAGCTGG	TRIM73	ENSG00000178809	-0.7138693622920851	[420]	[199,190,266,325]	-8	hSpCas9	negative selection	9521971
75399304	75399327	7	-	28162770	P31FUJ	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-1.5634475164028498	[82]	[32]	-7	hSpCas9	negative selection	10257181
75398969	75398992	7	-	28162770	P31FUJ	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-1.95065897563288	[124]	[37]	-8	hSpCas9	negative selection	10257182
75398951	75398974	7	-	28162770	P31FUJ	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.17663179924299455	[402]	[418]	-2	hSpCas9	negative selection	10257183
75403674	75403697	7	+	28162770	P31FUJ	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-6.4807297178579635	[75]	[0]	-9	hSpCas9	negative selection	10257184
75404892	75404915	7	-	28162770	P31FUJ	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.555552113645176	[438]	[350]	-5	hSpCas9	negative selection	10257185
75398990	75399013	7	-	28162770	P31FUJ	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-1.9616399176971844	[294]	[88]	-8	hSpCas9	negative selection	10257186
75399029	75399052	7	-	28162770	P31FUJ	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.8628525946640729	[324]	[209]	-6	hSpCas9	negative selection	10257187
75399058	75399081	7	-	28162770	P31FUJ	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.3264372765256086	[365]	[342]	-3	hSpCas9	negative selection	10257188
75399142	75399165	7	-	28162770	P31FUJ	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	-0.09805279230114106	[142]	[156]	-1	hSpCas9	negative selection	10257189
75399304	75399327	7	-	28162770	TF1	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10426547
75398969	75398992	7	-	28162770	TF1	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10426548
75398951	75398974	7	-	28162770	TF1	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	NaN	[NaN]	[367]	1	hSpCas9	negative selection	10426549
75403674	75403697	7	+	28162770	TF1	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10426550
75404892	75404915	7	-	28162770	TF1	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	NaN	[NaN]	[251]	1	hSpCas9	negative selection	10426551
75398990	75399013	7	-	28162770	TF1	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10426552
75399029	75399052	7	-	28162770	TF1	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	NaN	[NaN]	[184]	1	hSpCas9	negative selection	10426553
75399058	75399081	7	-	28162770	TF1	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10426554
75399142	75399165	7	-	28162770	TF1	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	NaN	[NaN]	[207]	1	hSpCas9	negative selection	10426555
75399304	75399327	7	-	28162770	SKM1	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-0.1439297929093677	[19]	[31]	-1	hSpCas9	negative selection	10595913
75398969	75398992	7	-	28162770	SKM1	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-1.0335058032157174	[43]	[37]	-6	hSpCas9	negative selection	10595914
75398951	75398974	7	-	28162770	SKM1	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.6109577092541008	[69]	[188]	6	hSpCas9	negative selection	10595915
75403674	75403697	7	+	28162770	SKM1	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-5.909464539272345	[33]	[0]	-9	hSpCas9	negative selection	10595916
75404892	75404915	7	-	28162770	SKM1	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.603167096098747	[115]	[134]	-5	hSpCas9	negative selection	10595917
75398990	75399013	7	-	28162770	SKM1	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-1.3704383227180479	[116]	[79]	-7	hSpCas9	negative selection	10595918
75399029	75399052	7	-	28162770	SKM1	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-1.0880765581758503	[94]	[78]	-7	hSpCas9	negative selection	10595919
75399058	75399081	7	-	28162770	SKM1	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.8411105209697102	[75]	[74]	-6	hSpCas9	negative selection	10595920
75399142	75399165	7	-	28162770	SKM1	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	0.3155018257279293	[29]	[65]	3	hSpCas9	negative selection	10595921
75399304	75399327	7	-	28162770	SKM1	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-0.1439297929093677	[19]	[31]	-1	hSpCas9	negative selection	10765279
75398969	75398992	7	-	28162770	SKM1	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-1.0335058032157174	[43]	[37]	-6	hSpCas9	negative selection	10765280
75398951	75398974	7	-	28162770	SKM1	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.6109577092541008	[69]	[188]	6	hSpCas9	negative selection	10765281
75403674	75403697	7	+	28162770	SKM1	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-5.909464539272345	[33]	[0]	-9	hSpCas9	negative selection	10765282
75404892	75404915	7	-	28162770	SKM1	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.603167096098747	[115]	[134]	-5	hSpCas9	negative selection	10765283
75398990	75399013	7	-	28162770	SKM1	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-1.3704383227180479	[116]	[79]	-7	hSpCas9	negative selection	10765284
75399029	75399052	7	-	28162770	SKM1	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-1.0880765581758503	[94]	[78]	-7	hSpCas9	negative selection	10765285
75399058	75399081	7	-	28162770	SKM1	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.8411105209697102	[75]	[74]	-6	hSpCas9	negative selection	10765286
75399142	75399165	7	-	28162770	SKM1	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	0.3155018257279293	[29]	[65]	3	hSpCas9	negative selection	10765287
75399304	75399327	7	-	28162770	PL21	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	0.29870344897290957	[98]	[52]	2	hSpCas9	negative selection	10934645
75398969	75398992	7	-	28162770	PL21	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-1.7694867364671614	[140]	[17]	-8	hSpCas9	negative selection	10934646
75398951	75398974	7	-	28162770	PL21	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.10968466354381647	[180]	[84]	1	hSpCas9	negative selection	10934647
75403674	75403697	7	+	28162770	PL21	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-3.5547478876741487	[107]	[3]	-9	hSpCas9	negative selection	10934648
75404892	75404915	7	-	28162770	PL21	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.9548350454870208	[431]	[96]	-6	hSpCas9	negative selection	10934649
75398990	75399013	7	-	28162770	PL21	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-0.6133241171509297	[354]	[100]	-4	hSpCas9	negative selection	10934650
75399029	75399052	7	-	28162770	PL21	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.21650713765118085	[298]	[111]	-1	hSpCas9	negative selection	10934651
75399058	75399081	7	-	28162770	PL21	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.1883130991985624	[232]	[88]	-1	hSpCas9	negative selection	10934652
75399142	75399165	7	-	28162770	PL21	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	1.0798453807716086	[99]	[91]	8	hSpCas9	negative selection	10934653
75399304	75399327	7	-	28162770	P31FUJ	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-1.5634475164028498	[82]	[32]	-7	hSpCas9	negative selection	11104011
75398969	75398992	7	-	28162770	P31FUJ	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-1.95065897563288	[124]	[37]	-8	hSpCas9	negative selection	11104012
75398951	75398974	7	-	28162770	P31FUJ	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.17663179924299455	[402]	[418]	-2	hSpCas9	negative selection	11104013
75403674	75403697	7	+	28162770	P31FUJ	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-6.4807297178579635	[75]	[0]	-9	hSpCas9	negative selection	11104014
75404892	75404915	7	-	28162770	P31FUJ	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.555552113645176	[438]	[350]	-5	hSpCas9	negative selection	11104015
75398990	75399013	7	-	28162770	P31FUJ	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-1.9616399176971844	[294]	[88]	-8	hSpCas9	negative selection	11104016
75399029	75399052	7	-	28162770	P31FUJ	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.8628525946640729	[324]	[209]	-6	hSpCas9	negative selection	11104017
75399058	75399081	7	-	28162770	P31FUJ	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.3264372765256086	[365]	[342]	-3	hSpCas9	negative selection	11104018
75399142	75399165	7	-	28162770	P31FUJ	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	-0.09805279230114106	[142]	[156]	-1	hSpCas9	negative selection	11104019
75399304	75399327	7	-	28162770	OCIAML5	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-3.3666397436937547	[39]	[6]	-9	hSpCas9	negative selection	11273377
75398969	75398992	7	-	28162770	OCIAML5	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-2.3775280598364916	[94]	[32]	-8	hSpCas9	negative selection	11273378
75398951	75398974	7	-	28162770	OCIAML5	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.5054764217423655	[231]	[294]	-3	hSpCas9	negative selection	11273379
75403674	75403697	7	+	28162770	OCIAML5	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-6.524491912835493	[50]	[0]	-9	hSpCas9	negative selection	11273380
75404892	75404915	7	-	28162770	OCIAML5	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.48357165752218323	[188]	[243]	-3	hSpCas9	negative selection	11273381
75398990	75399013	7	-	28162770	OCIAML5	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-0.7999152888128902	[162]	[168]	-5	hSpCas9	negative selection	11273382
75399029	75399052	7	-	28162770	OCIAML5	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-1.78495237500546	[146]	[76]	-7	hSpCas9	negative selection	11273383
75399058	75399081	7	-	28162770	OCIAML5	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	0.10852504457776768	[166]	[324]	0	hSpCas9	negative selection	11273384
75399142	75399165	7	-	28162770	OCIAML5	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	-0.0477910417383649	[66]	[116]	0	hSpCas9	negative selection	11273385
75399304	75399327	7	-	28162770	EOL1	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-3.1629150696798045	[84]	[4]	-9	hSpCas9	negative selection	11442743
75398969	75398992	7	-	28162770	EOL1	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-0.9446656208941113	[273]	[74]	-6	hSpCas9	negative selection	11442744
75398951	75398974	7	-	28162770	EOL1	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.34182374304537766	[321]	[214]	3	hSpCas9	negative selection	11442745
75403674	75403697	7	+	28162770	EOL1	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-6.313856967754544	[150]	[0]	-9	hSpCas9	negative selection	11442746
75404892	75404915	7	-	28162770	EOL1	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	0.3983313620675437	[781]	[542]	3	hSpCas9	negative selection	11442747
75398990	75399013	7	-	28162770	EOL1	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-0.20056414868639616	[625]	[286]	-1	hSpCas9	negative selection	11442748
75399029	75399052	7	-	28162770	EOL1	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.509548063523994	[507]	[187]	-4	hSpCas9	negative selection	11442749
75399058	75399081	7	-	28162770	EOL1	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.6024673799413418	[365]	[126]	-4	hSpCas9	negative selection	11442750
75399142	75399165	7	-	28162770	EOL1	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	-0.8777715605897711	[142]	[40]	-6	hSpCas9	negative selection	11442751
75399304	75399327	7	-	28162770	MOLM13	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-0.4191016566262349	[134]	[72]	-3	hSpCas9	negative selection	11612109
75398969	75398992	7	-	28162770	MOLM13	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-1.010651060040423	[208]	[74]	-5	hSpCas9	negative selection	11612110
75398951	75398974	7	-	28162770	MOLM13	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.4185940852878052	[386]	[373]	3	hSpCas9	negative selection	11612111
75403674	75403697	7	+	28162770	MOLM13	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-5.1663166381964265	[148]	[2]	-9	hSpCas9	negative selection	11612112
75404892	75404915	7	-	28162770	MOLM13	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.23546781997880772	[494]	[303]	-1	hSpCas9	negative selection	11612113
75398990	75399013	7	-	28162770	MOLM13	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-1.6204664928762682	[403]	[94]	-7	hSpCas9	negative selection	11612114
75399029	75399052	7	-	28162770	MOLM13	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-1.137982108939558	[416]	[136]	-5	hSpCas9	negative selection	11612115
75399058	75399081	7	-	28162770	MOLM13	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.4101200940768109	[271]	[147]	-2	hSpCas9	negative selection	11612116
75399142	75399165	7	-	28162770	MOLM13	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	-0.3492465613056108	[184]	[104]	-2	hSpCas9	negative selection	11612117
75399304	75399327	7	-	28162770	HEL	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-2.8166927866369402	[87]	[7]	-8	hSpCas9	negative selection	11781475
75398969	75398992	7	-	28162770	HEL	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	0.5778876876503889	[181]	[173]	5	hSpCas9	negative selection	11781476
75398951	75398974	7	-	28162770	HEL	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.27416064381417315	[274]	[212]	2	hSpCas9	negative selection	11781477
75403674	75403697	7	+	28162770	HEL	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-0.45854450383682455	[117]	[54]	-3	hSpCas9	negative selection	11781478
75404892	75404915	7	-	28162770	HEL	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.6215672310694855	[453]	[188]	-4	hSpCas9	negative selection	11781479
75398990	75399013	7	-	28162770	HEL	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-0.8396539350802517	[474]	[169]	-5	hSpCas9	negative selection	11781480
75399029	75399052	7	-	28162770	HEL	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.6718659220811467	[392]	[157]	-4	hSpCas9	negative selection	11781481
75399058	75399081	7	-	28162770	HEL	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.05264765841444974	[284]	[175]	0	hSpCas9	negative selection	11781482
75399142	75399165	7	-	28162770	HEL	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	0.4743413003046383	[117]	[104]	4	hSpCas9	negative selection	11781483
75399304	75399327	7	-	28162770	MV411	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-2.5426393798429934	[82]	[11]	-8	hSpCas9	negative selection	11950841
75398969	75398992	7	-	28162770	MV411	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-0.41271244633259985	[127]	[80]	-3	hSpCas9	negative selection	11950842
75398951	75398974	7	-	28162770	MV411	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	0.9232152146895984	[235]	[376]	8	hSpCas9	negative selection	11950843
75403674	75403697	7	+	28162770	MV411	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-6.2761244052742375	[91]	[0]	-9	hSpCas9	negative selection	11950844
75404892	75404915	7	-	28162770	MV411	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-1.1335564849691044	[348]	[133]	-6	hSpCas9	negative selection	11950845
75398990	75399013	7	-	28162770	MV411	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-1.3456528308217812	[355]	[117]	-7	hSpCas9	negative selection	11950846
75399029	75399052	7	-	28162770	MV411	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.644921726029255	[283]	[152]	-4	hSpCas9	negative selection	11950847
75399058	75399081	7	-	28162770	MV411	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	0.05661520844719725	[225]	[197]	0	hSpCas9	negative selection	11950848
75399142	75399165	7	-	28162770	MV411	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	0.9333289603547124	[68]	[110]	8	hSpCas9	negative selection	11950849
75399304	75399327	7	-	28162770	MONOMAC1	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-0.7550323001804407	[52]	[35]	-6	hSpCas9	negative selection	12120207
75398969	75398992	7	-	28162770	MONOMAC1	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-1.1578662497788759	[108]	[55]	-7	hSpCas9	negative selection	12120208
75398951	75398974	7	-	28162770	MONOMAC1	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.2593211253138965	[141]	[135]	-2	hSpCas9	negative selection	12120209
75403674	75403697	7	+	28162770	MONOMAC1	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-1.492492730585725	[53]	[21]	-8	hSpCas9	negative selection	12120210
75404892	75404915	7	-	28162770	MONOMAC1	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	0.2045801364569686	[242]	[320]	2	hSpCas9	negative selection	12120211
75398990	75399013	7	-	28162770	MONOMAC1	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-0.5332555994973097	[278]	[220]	-4	hSpCas9	negative selection	12120212
75399029	75399052	7	-	28162770	MONOMAC1	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.6365689082591462	[197]	[145]	-5	hSpCas9	negative selection	12120213
75399058	75399081	7	-	28162770	MONOMAC1	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.11560924771570777	[154]	[163]	-1	hSpCas9	negative selection	12120214
75399142	75399165	7	-	28162770	MONOMAC1	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	0.24353574432642755	[83]	[113]	2	hSpCas9	negative selection	12120215
75399304	75399327	7	-	28162770	OCIAML2	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-0.011198206604864147	[7]	[43]	0	hSpCas9	negative selection	12289573
75398969	75398992	7	-	28162770	OCIAML2	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-0.799252572703532	[26]	[85]	-5	hSpCas9	negative selection	12289574
75398951	75398974	7	-	28162770	OCIAML2	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.8409982751872767	[52]	[163]	-5	hSpCas9	negative selection	12289575
75403674	75403697	7	+	28162770	OCIAML2	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-4.277984747299765	[13]	[3]	-9	hSpCas9	negative selection	12289576
75404892	75404915	7	-	28162770	OCIAML2	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.31807195576993696	[64]	[288]	-3	hSpCas9	negative selection	12289577
75398990	75399013	7	-	28162770	OCIAML2	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-1.541019153133559	[62]	[119]	-7	hSpCas9	negative selection	12289578
75399029	75399052	7	-	28162770	OCIAML2	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.4971020366033522	[54]	[215]	-4	hSpCas9	negative selection	12289579
75399058	75399081	7	-	28162770	OCIAML2	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.2794883378901529	[29]	[136]	-2	hSpCas9	negative selection	12289580
75399142	75399165	7	-	28162770	OCIAML2	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	-1.163968487008109	[18]	[46]	-6	hSpCas9	negative selection	12289581
75399304	75399327	7	-	28162770	OCIAML3	viability	GCGGCTGCAGACGGTGGAGACGG	TRIM73	ENSG00000178809	-1.4134353946823424	[29]	[33]	-7	hSpCas9	negative selection	12458939
75398969	75398992	7	-	28162770	OCIAML3	viability	GGCAGATGGGACACTGAAGCCGG	TRIM73	ENSG00000178809	-1.8640968036919077	[40]	[33]	-8	hSpCas9	negative selection	12458940
75398951	75398974	7	-	28162770	OCIAML3	viability	GCCGGTCCTCCAGCTCCAGCAGG	TRIM73	ENSG00000178809	-0.789263931723097	[78]	[137]	-5	hSpCas9	negative selection	12458941
75403674	75403697	7	+	28162770	OCIAML3	viability	GAAGCAGGAGCAGAAGAAGGTGG	TRIM73	ENSG00000178809	-4.548203950711039	[30]	[3]	-9	hSpCas9	negative selection	12458942
75404892	75404915	7	-	28162770	OCIAML3	viability	CCTTCTCCTCGTCCACCGGGTGG	TRIM73	ENSG00000178809	-0.8894635238503346	[134]	[219]	-6	hSpCas9	negative selection	12458943
75398990	75399013	7	-	28162770	OCIAML3	viability	GGGACTCCTTGAAGACCTCCAGG	TRIM73	ENSG00000178809	-1.7595937060421383	[82]	[73]	-8	hSpCas9	negative selection	12458944
75399029	75399052	7	-	28162770	OCIAML3	viability	GGCAGCCCTTGCAGTAGGAGTGG	TRIM73	ENSG00000178809	-0.3637100209023689	[77]	[182]	-3	hSpCas9	negative selection	12458945
75399058	75399081	7	-	28162770	OCIAML3	viability	GGTGTCCAGGTGGTAGGACAGGG	TRIM73	ENSG00000178809	-0.5841598543678159	[72]	[146]	-4	hSpCas9	negative selection	12458946
75399142	75399165	7	-	28162770	OCIAML3	viability	GGCTTCGATCACCCAGGCCAGGG	TRIM73	ENSG00000178809	-0.3209891459177474	[23]	[57]	-3	hSpCas9	negative selection	12458947