Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7272
• Symbol:TTK
• Description:TTK protein kinase

DataSource: http://genomecrispr.dkfz.de/#!/results/TTK

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
80007837	80007860	6	+	26472758	Jiyoye	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-2.829863815794976	[131]	[13]	-9	hSpCas9	negative selection	174786
80011515	80011538	6	+	26472758	Jiyoye	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	-1.4352833415076465	[103]	[28]	-7	hSpCas9	negative selection	174787
80022354	80022377	6	+	26472758	Jiyoye	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-0.11845297983288064	[130]	[90]	-1	hSpCas9	negative selection	174788
80027916	80027939	6	-	26472758	Jiyoye	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-1.0599506289214247	[281]	[101]	-6	hSpCas9	negative selection	174789
80031527	80031550	6	+	26472758	Jiyoye	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-1.1512453317627909	[376]	[127]	-7	hSpCas9	negative selection	174790
80010917	80010940	6	+	26472758	Jiyoye	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-2.0190893731962247	[42]	[7]	-8	hSpCas9	negative selection	174791
80011496	80011519	6	+	26472758	Jiyoye	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-1.8152170398305745	[69]	[14]	-8	hSpCas9	negative selection	174792
80022451	80022474	6	+	26472758	Jiyoye	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.040283595465348	[89]	[32]	-6	hSpCas9	negative selection	174793
80027948	80027971	6	-	26472758	Jiyoye	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-1.4717328015767648	[216]	[58]	-7	hSpCas9	negative selection	174794
80010877	80010900	6	+	26472758	Jiyoye	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-1.7591830049162467	[201]	[44]	-8	hSpCas9	negative selection	174795
80007837	80007860	6	+	26472758	KBM7	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-1.389464277713322	[616,352]	[36,127]	-7	hSpCas9	negative selection	365904
80011515	80011538	6	+	26472758	KBM7	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	0.20310486001417982	[267,188]	[91,148]	2	hSpCas9	negative selection	365905
80022354	80022377	6	+	26472758	KBM7	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-0.25906352680567696	[401,336]	[161,128]	-2	hSpCas9	negative selection	365906
80027916	80027939	6	-	26472758	KBM7	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	0.23336652858079165	[862,695]	[706,178]	2	hSpCas9	negative selection	365907
80031527	80031550	6	+	26472758	KBM7	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-0.4590249444854524	[1152,880]	[442,256]	-4	hSpCas9	negative selection	365908
80010917	80010940	6	+	26472758	KBM7	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-0.5470757464925474	[297,192]	[102,54]	-5	hSpCas9	negative selection	365909
80011496	80011519	6	+	26472758	KBM7	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-0.5090849610197181	[140,170]	[74,31]	-4	hSpCas9	negative selection	365910
80022451	80022474	6	+	26472758	KBM7	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.2094591106060686	[370,314]	[78,60]	-7	hSpCas9	negative selection	365911
80027948	80027971	6	-	26472758	KBM7	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-0.14272814714750942	[399,405]	[198,148]	-1	hSpCas9	negative selection	365912
80010877	80010900	6	+	26472758	KBM7	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-0.5047290896383723	[721,483]	[238,158]	-4	hSpCas9	negative selection	365913
80007837	80007860	6	+	26472758	Raji	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-2.823353802189287	[243]	[7]	-9	hSpCas9	negative selection	557022
80011515	80011538	6	+	26472758	Raji	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	0.8568400737230024	[68]	[28]	7	hSpCas9	negative selection	557023
80022354	80022377	6	+	26472758	Raji	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	0.1724785635954844	[129]	[33]	1	hSpCas9	negative selection	557024
80027916	80027939	6	-	26472758	Raji	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-2.0585284035620894	[358]	[19]	-8	hSpCas9	negative selection	557025
80031527	80031550	6	+	26472758	Raji	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-1.0844840189493898	[529]	[57]	-7	hSpCas9	negative selection	557026
80010917	80010940	6	+	26472758	Raji	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-0.5364726544011253	[99]	[15]	-4	hSpCas9	negative selection	557027
80011496	80011519	6	+	26472758	Raji	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-0.8666212560934561	[54]	[6]	-6	hSpCas9	negative selection	557028
80022451	80022474	6	+	26472758	Raji	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.3866053053000664	[168]	[14]	-7	hSpCas9	negative selection	557029
80027948	80027971	6	-	26472758	Raji	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-1.3694301614919344	[166]	[14]	-7	hSpCas9	negative selection	557030
80010877	80010900	6	+	26472758	Raji	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-1.6877966727379023	[471]	[33]	-8	hSpCas9	negative selection	557031
80007837	80007860	6	+	26472758	K562	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-2.0982182640530245	[420]	[82]	-7	hSpCas9	negative selection	748140
80011515	80011538	6	+	26472758	K562	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	0.9118433885795758	[152]	[242]	7	hSpCas9	negative selection	748141
80022354	80022377	6	+	26472758	K562	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-0.23604184661044547	[405]	[290]	-2	hSpCas9	negative selection	748142
80027916	80027939	6	-	26472758	K562	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-0.7220287126225267	[679]	[347]	-4	hSpCas9	negative selection	748143
80031527	80031550	6	+	26472758	K562	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-2.479423586001211	[838]	[126]	-8	hSpCas9	negative selection	748144
80010917	80010940	6	+	26472758	K562	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-1.0714855795931453	[238]	[95]	-5	hSpCas9	negative selection	748145
80011496	80011519	6	+	26472758	K562	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	0.589247224663888	[99]	[126]	5	hSpCas9	negative selection	748146
80022451	80022474	6	+	26472758	K562	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.562936194391157	[251]	[71]	-7	hSpCas9	negative selection	748147
80027948	80027971	6	-	26472758	K562	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-0.5052579182493133	[379]	[225]	-3	hSpCas9	negative selection	748148
80010877	80010900	6	+	26472758	K562	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-2.0487264665918863	[396]	[80]	-7	hSpCas9	negative selection	748149
80007842	80007865	6	+	26627737	DLD1	viability	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-3.860688350986814	[910]	[1,45,12]	-9	hSpCas9	negative selection	833795
80011467	80011490	6	-	26627737	DLD1	viability	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.628658360199928	[1225]	[771,542,477]	6	hSpCas9	negative selection	833796
80007842	80007865	6	+	26627737	GBM cells	viability after 5 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-3.2840909536006166	[553]	[19,40]	-9	hSpCas9	negative selection	916110
80011467	80011490	6	-	26627737	GBM cells	viability after 5 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	-0.0580649737455845	[891]	[457,460]	-1	hSpCas9	negative selection	916111
80007842	80007865	6	+	26627737	GBM cells	viability after 13 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-4.298816382876433	[553]	[6,21]	-9	hSpCas9	negative selection	998425
80011467	80011490	6	-	26627737	GBM cells	viability after 13 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.1726775024062599	[891]	[689,427]	2	hSpCas9	negative selection	998426
80007842	80007865	6	+	26627737	GBM cells	viability after 21 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-5.7916713078109705	[553]	[6,3]	-9	hSpCas9	negative selection	1080740
80011467	80011490	6	-	26627737	GBM cells	viability after 21 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	-0.15701158715989183	[891]	[454,415]	-1	hSpCas9	negative selection	1080741
80007842	80007865	6	+	26627737	RPE1	viability after 9 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-2.8265383186094453	[958]	[47,34]	-9	hSpCas9	negative selection	1163055
80011467	80011490	6	-	26627737	RPE1	viability after 9 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.521687478406879	[1777]	[737,877]	3	hSpCas9	negative selection	1163056
80007842	80007865	6	+	26627737	RPE1	viability after 12 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-3.7018470681527456	[958]	[12,26]	-9	hSpCas9	negative selection	1245370
80011467	80011490	6	-	26627737	RPE1	viability after 12 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.1762766060489669	[1777]	[582,493]	1	hSpCas9	negative selection	1245371
80007842	80007865	6	+	26627737	RPE1	viability after 15 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-6.070640790617363	[958]	[1,5]	-9	hSpCas9	negative selection	1327685
80011467	80011490	6	-	26627737	RPE1	viability after 15 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.172562992088527	[1777]	[658,477]	1	hSpCas9	negative selection	1327686
80007842	80007865	6	+	26627737	RPE1	viability after 18 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-3.1063232721189964	[958]	[16,43]	-9	hSpCas9	negative selection	1410000
80011467	80011490	6	-	26627737	RPE1	viability after 18 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.11327207552391605	[1777]	[606,424]	0	hSpCas9	negative selection	1410001
80007842	80007865	6	+	26627737	HeLa	viability after 8 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-2.3934569938389947	[1261]	[186,14,127]	-9	hSpCas9	negative selection	1492315
80011467	80011490	6	-	26627737	HeLa	viability after 8 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.14981880476665932	[1368]	[716,705,577]	1	hSpCas9	negative selection	1492316
80007842	80007865	6	+	26627737	HeLa	viability after 12 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-3.584411695237926	[1261]	[67,25,38]	-9	hSpCas9	negative selection	1574630
80011467	80011490	6	-	26627737	HeLa	viability after 12 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.27219848941514946	[1368]	[851,707,491]	2	hSpCas9	negative selection	1574631
80007842	80007865	6	+	26627737	HeLa	viability after 15 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-2.0388618594429455	[1261]	[45,157,175]	-9	hSpCas9	negative selection	1656945
80011467	80011490	6	-	26627737	HeLa	viability after 15 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.5726562834529527	[1368]	[937,660,890]	4	hSpCas9	negative selection	1656946
80007842	80007865	6	+	26627737	HeLa	viability after 18 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-1.9928973711948723	[1261]	[36,132,175]	-9	hSpCas9	negative selection	1739260
80011467	80011490	6	-	26627737	HeLa	viability after 18 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.6048406194927496	[1368]	[657,556,890]	5	hSpCas9	negative selection	1739261
80007842	80007865	6	+	26627737	HCT116	viability after 6 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	0.022845653266515775	[1083]	[448,20]	0	hSpCas9	negative selection	1821575
80011467	80011490	6	-	26627737	HCT116	viability after 6 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.5999848699037547	[2025]	[222,625]	3	hSpCas9	negative selection	1821576
80007842	80007865	6	+	26627737	HCT116	viability after 8 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-3.031861412434556	[889]	[23,74,79]	-9	hSpCas9	negative selection	1903890
80011467	80011490	6	-	26627737	HCT116	viability after 8 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.5607956162972878	[784]	[625,653,633]	5	hSpCas9	negative selection	1903891
80007842	80007865	6	+	26627737	HCT116	viability after 9 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-0.9524187707663445	[1083]	[310,21]	-6	hSpCas9	negative selection	1986205
80011467	80011490	6	-	26627737	HCT116	viability after 9 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.24142271075277555	[2025]	[562,699]	1	hSpCas9	negative selection	1986206
80007842	80007865	6	+	26627737	HCT116	viability after 12 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-4.539951045966159	[889]	[16,36,6]	-9	hSpCas9	negative selection	2068520
80011467	80011490	6	-	26627737	HCT116	viability after 12 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.10839048333573342	[784]	[415,456,463]	1	hSpCas9	negative selection	2068521
80007842	80007865	6	+	26627737	HCT116	viability after 15 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-3.258906917274242	[889]	[28,56,70]	-9	hSpCas9	negative selection	2150835
80011467	80011490	6	-	26627737	HCT116	viability after 15 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.41870121938001725	[784]	[733,498,590]	4	hSpCas9	negative selection	2150836
80007842	80007865	6	+	26627737	HCT116	viability after 18 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-4.289105797182075	[889]	[47,2,15]	-9	hSpCas9	negative selection	2233150
80011467	80011490	6	-	26627737	HCT116	viability after 18 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.45438624665575844	[784]	[553,548,451]	4	hSpCas9	negative selection	2233151
80005834	80005857	6	+	24336569	HL60	viability	TTTCTTAGAAATGGAATCCGAGG	TTK	ENSG00000112742	0.11654416208059232	[536]	[1231]	1	hSpCas9	negative selection	2304123
80005844	80005867	6	+	24336569	HL60	viability	ATGGAATCCGAGGATTTAAGTGG	TTK	ENSG00000112742	-0.5430441858447703	[545]	[792]	-5	hSpCas9	negative selection	2304124
80005851	80005874	6	-	24336569	HL60	viability	TTCTCTGCCACTTAAATCCTCGG	TTK	ENSG00000112742	0.8663259656530734	[414]	[1600]	7	hSpCas9	negative selection	2304125
80005887	80005910	6	-	24336569	HL60	viability	GTCTCTCACTTTGTTCATTATGG	TTK	ENSG00000112742	0.4497582010764112	[391]	[1132]	4	hSpCas9	negative selection	2304126
80005936	80005959	6	-	24336569	HL60	viability	TCAAGCTTAGTTCATCAGTAAGG	TTK	ENSG00000112742	-0.6760767713837716	[224]	[297]	-6	hSpCas9	negative selection	2304127
80007822	80007845	6	+	24336569	HL60	viability	TGTTAACCAAATTATGATGATGG	TTK	ENSG00000112742	0.8525869527810578	[441]	[1688]	7	hSpCas9	negative selection	2304128
80007828	80007851	6	-	24336569	HL60	viability	TGTTTGCCATCATCATAATTTGG	TTK	ENSG00000112742	0.35207598487637703	[551]	[1490]	3	hSpCas9	negative selection	2304129
80007837	80007860	6	+	24336569	HL60	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-2.1473019139916425	[1613]	[770]	-9	hSpCas9	negative selection	2304130
80007842	80007865	6	+	24336569	HL60	viability	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-0.4852705443935046	[980]	[1482]	-4	hSpCas9	negative selection	2304131
80007852	80007875	6	-	24336569	HL60	viability	ACAAACTCAACCAGTCCTCTGGG	TTK	ENSG00000112742	0.3864103897326422	[696]	[1927]	3	hSpCas9	negative selection	2304132
80005834	80005857	6	+	24336569	KBM7	viability	TTTCTTAGAAATGGAATCCGAGG	TTK	ENSG00000112742	0.5702933725163839	[360]	[1461]	5	hSpCas9	negative selection	2371300
80005844	80005867	6	+	24336569	KBM7	viability	ATGGAATCCGAGGATTTAAGTGG	TTK	ENSG00000112742	1.142436531898559	[284]	[1715]	8	hSpCas9	negative selection	2371301
80005851	80005874	6	-	24336569	KBM7	viability	TTCTCTGCCACTTAAATCCTCGG	TTK	ENSG00000112742	0.32458007591883176	[408]	[1396]	3	hSpCas9	negative selection	2371302
80005887	80005910	6	-	24336569	KBM7	viability	GTCTCTCACTTTGTTCATTATGG	TTK	ENSG00000112742	-0.031052079129552212	[241]	[645]	0	hSpCas9	negative selection	2371303
80005936	80005959	6	-	24336569	KBM7	viability	TCAAGCTTAGTTCATCAGTAAGG	TTK	ENSG00000112742	-2.2615672109389333	[108]	[61]	-8	hSpCas9	negative selection	2371304
80007822	80007845	6	+	24336569	KBM7	viability	TGTTAACCAAATTATGATGATGG	TTK	ENSG00000112742	0.37743970244464076	[660]	[2341]	3	hSpCas9	negative selection	2371305
80007828	80007851	6	-	24336569	KBM7	viability	TGTTTGCCATCATCATAATTTGG	TTK	ENSG00000112742	0.677139128464277	[406]	[1774]	6	hSpCas9	negative selection	2371306
80007837	80007860	6	+	24336569	KBM7	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-2.2947046472990875	[1323]	[735]	-8	hSpCas9	negative selection	2371307
80007842	80007865	6	+	24336569	KBM7	viability	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-0.611976200420379	[1220]	[2178]	-5	hSpCas9	negative selection	2371308
80007852	80007875	6	-	24336569	KBM7	viability	ACAAACTCAACCAGTCCTCTGGG	TTK	ENSG00000112742	1.0637750792826934	[257]	[1470]	8	hSpCas9	negative selection	2371309
80004404	80004427	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGGTTAAACTGGAAAGACCAGG	TTK	ENSG00000112742	1.8499707941339265	[4,58]	[39,9]	6	dCas9-VP64	positive selection	2432338
80004487	80004510	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCGCACGGGTGGGGTCGCGG	TTK	ENSG00000112742	-1.7447395511580406	[74,136]	[2,9]	-8	dCas9-VP64	positive selection	2432339
80004465	80004488	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCAGCACCCTACCAACCCAGG	TTK	ENSG00000112742	0.18726157954002298	[20,7]	[3,1]	0	dCas9-VP64	positive selection	2432340
80004404	80004427	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGGTTAAACTGGAAAGACCAGG	TTK	ENSG00000112742	-0.8135478747756912	[63,58]	[6,14]	-7	dCas9-VP64	positive selection	2527593
80004487	80004510	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCGCACGGGTGGGGTCGCGG	TTK	ENSG00000112742	0.19094485358889024	[40,10]	[7,10]	1	dCas9-VP64	positive selection	2527594
80004465	80004488	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCAGCACCCTACCAACCCAGG	TTK	ENSG00000112742	-0.7364501546302158	[103,55]	[20,9]	-7	dCas9-VP64	positive selection	2527595
80011739	80011762	6	+	27260157	DLD1	viability	CCACCACAAGATGCAGAAATAGG	TTK	ENSG00000112742	-0.0607951434830178	[]	[]	0	hSpCas9	negative selection	2574301
80007842	80007865	6	+	27260157	DLD1	viability	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-2.09227683721347	[]	[]	-8	hSpCas9	negative selection	2575760
80013284	80013307	6	-	27260157	DLD1	viability	ATCTCGGCATTCTGATCTAGAGG	TTK	ENSG00000112742	-1.5417907571164	[]	[]	-8	hSpCas9	negative selection	2577661
80007837	80007860	6	+	27260157	DLD1	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-5.34405867003059	[]	[]	-9	hSpCas9	negative selection	2579016
80005834	80005857	6	+	27260157	DLD1	viability	TTTCTTAGAAATGGAATCCGAGG	TTK	ENSG00000112742	-0.702546396545187	[]	[]	-5	hSpCas9	negative selection	2580088
80010877	80010900	6	+	27260157	DLD1	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-4.00676627792919	[]	[]	-9	hSpCas9	negative selection	2584009
80005851	80005874	6	-	27260157	DLD1	viability	TTCTCTGCCACTTAAATCCTCGG	TTK	ENSG00000112742	-1.08392192327194	[]	[]	-7	hSpCas9	negative selection	2587698
80011467	80011490	6	-	27260157	DLD1	viability	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	-2.3696676868815	[]	[]	-9	hSpCas9	negative selection	2609225
80007852	80007875	6	-	27260157	DLD1	viability	ACAAACTCAACCAGTCCTCTGGG	TTK	ENSG00000112742	-1.05977985747408	[]	[]	-7	hSpCas9	negative selection	2614756
80005936	80005959	6	-	27260157	DLD1	viability	TCAAGCTTAGTTCATCAGTAAGG	TTK	ENSG00000112742	-1.3030389188772	[]	[]	-7	hSpCas9	negative selection	2616238
80005887	80005910	6	-	27260157	DLD1	viability	GTCTCTCACTTTGTTCATTATGG	TTK	ENSG00000112742	-0.861152982224655	[]	[]	-6	hSpCas9	negative selection	2619482
80010917	80010940	6	+	27260157	DLD1	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-2.09913796380116	[]	[]	-8	hSpCas9	negative selection	2621464
80007828	80007851	6	-	27260157	DLD1	viability	TGTTTGCCATCATCATAATTTGG	TTK	ENSG00000112742	-0.900921019423132	[]	[]	-6	hSpCas9	negative selection	2621976
80010863	80010886	6	+	27260157	DLD1	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-3.28842284219016	[]	[]	-9	hSpCas9	negative selection	2622762
80005844	80005867	6	+	27260157	DLD1	viability	ATGGAATCCGAGGATTTAAGTGG	TTK	ENSG00000112742	-1.01763186227729	[]	[]	-7	hSpCas9	negative selection	2640983
80008396	80008419	6	-	27260157	DLD1	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-2.30188419868303	[]	[]	-9	hSpCas9	negative selection	2646399
80011739	80011762	6	-	27260157	DLD1	viability	CCTATTTCTGCATCTTGTGGTGG	TTK	ENSG00000112742	-1.49447398558683	[]	[]	-8	hSpCas9	negative selection	2646847
80007822	80007845	6	+	27260157	DLD1	viability	TGTTAACCAAATTATGATGATGG	TTK	ENSG00000112742	-0.432448183896776	[]	[]	-4	hSpCas9	negative selection	2648660
80011739	80011762	6	+	27260157	HT1080	viability	CCACCACAAGATGCAGAAATAGG	TTK	ENSG00000112742	-1.18343745684908	[]	[]	-8	hSpCas9	negative selection	2650431
80007842	80007865	6	+	27260157	HT1080	viability	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-1.01887832206135	[]	[]	-8	hSpCas9	negative selection	2651890
80013284	80013307	6	-	27260157	HT1080	viability	ATCTCGGCATTCTGATCTAGAGG	TTK	ENSG00000112742	-1.42736317662093	[]	[]	-9	hSpCas9	negative selection	2653791
80007837	80007860	6	+	27260157	HT1080	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-3.08941722002577	[]	[]	-9	hSpCas9	negative selection	2655146
80005834	80005857	6	+	27260157	HT1080	viability	TTTCTTAGAAATGGAATCCGAGG	TTK	ENSG00000112742	-0.167536945672111	[]	[]	0	hSpCas9	negative selection	2656218
80010877	80010900	6	+	27260157	HT1080	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-1.98101665564734	[]	[]	-9	hSpCas9	negative selection	2660139
80005851	80005874	6	-	27260157	HT1080	viability	TTCTCTGCCACTTAAATCCTCGG	TTK	ENSG00000112742	-1.75123795878771	[]	[]	-9	hSpCas9	negative selection	2663828
80011467	80011490	6	-	27260157	HT1080	viability	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	-1.21219509900175	[]	[]	-8	hSpCas9	negative selection	2685355
80007852	80007875	6	-	27260157	HT1080	viability	ACAAACTCAACCAGTCCTCTGGG	TTK	ENSG00000112742	-0.436891484304058	[]	[]	-7	hSpCas9	negative selection	2690886
80005936	80005959	6	-	27260157	HT1080	viability	TCAAGCTTAGTTCATCAGTAAGG	TTK	ENSG00000112742	-0.02657804107182	[]	[]	0	hSpCas9	negative selection	2692368
80005887	80005910	6	-	27260157	HT1080	viability	GTCTCTCACTTTGTTCATTATGG	TTK	ENSG00000112742	-0.1337087055547	[]	[]	0	hSpCas9	negative selection	2695612
80010917	80010940	6	+	27260157	HT1080	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-2.08928557594863	[]	[]	-9	hSpCas9	negative selection	2697594
80007828	80007851	6	-	27260157	HT1080	viability	TGTTTGCCATCATCATAATTTGG	TTK	ENSG00000112742	0.556292618413005	[]	[]	5	hSpCas9	negative selection	2698106
80010863	80010886	6	+	27260157	HT1080	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.737302419997798	[]	[]	-8	hSpCas9	negative selection	2698892
80005844	80005867	6	+	27260157	HT1080	viability	ATGGAATCCGAGGATTTAAGTGG	TTK	ENSG00000112742	-1.14110899472007	[]	[]	-8	hSpCas9	negative selection	2717113
80008396	80008419	6	-	27260157	HT1080	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-1.24714594707496	[]	[]	-9	hSpCas9	negative selection	2722529
80011739	80011762	6	-	27260157	HT1080	viability	CCTATTTCTGCATCTTGTGGTGG	TTK	ENSG00000112742	-2.38430507687279	[]	[]	-9	hSpCas9	negative selection	2722977
80007822	80007845	6	+	27260157	HT1080	viability	TGTTAACCAAATTATGATGATGG	TTK	ENSG00000112742	0.193891381517443	[]	[]	1	hSpCas9	negative selection	2724790
80011739	80011762	6	+	27260157	MKN45	viability	CCACCACAAGATGCAGAAATAGG	TTK	ENSG00000112742	-1.60573540455483	[]	[]	-9	hSpCas9	negative selection	2726561
80007842	80007865	6	+	27260157	MKN45	viability	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-1.70118428378189	[]	[]	-9	hSpCas9	negative selection	2728020
80013284	80013307	6	-	27260157	MKN45	viability	ATCTCGGCATTCTGATCTAGAGG	TTK	ENSG00000112742	-2.18829879080647	[]	[]	-9	hSpCas9	negative selection	2729921
80007837	80007860	6	+	27260157	MKN45	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-2.50622042905431	[]	[]	-9	hSpCas9	negative selection	2731276
80005834	80005857	6	+	27260157	MKN45	viability	TTTCTTAGAAATGGAATCCGAGG	TTK	ENSG00000112742	-0.223595928949942	[]	[]	-1	hSpCas9	negative selection	2732348
80010877	80010900	6	+	27260157	MKN45	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-1.2685224000678	[]	[]	-8	hSpCas9	negative selection	2736269
80005851	80005874	6	-	27260157	MKN45	viability	TTCTCTGCCACTTAAATCCTCGG	TTK	ENSG00000112742	-1.08692820040277	[]	[]	-8	hSpCas9	negative selection	2739958
80011467	80011490	6	-	27260157	MKN45	viability	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	-1.92106591587275	[]	[]	-9	hSpCas9	negative selection	2761485
80007852	80007875	6	-	27260157	MKN45	viability	ACAAACTCAACCAGTCCTCTGGG	TTK	ENSG00000112742	-0.986026763629298	[]	[]	-7	hSpCas9	negative selection	2767016
80005936	80005959	6	-	27260157	MKN45	viability	TCAAGCTTAGTTCATCAGTAAGG	TTK	ENSG00000112742	-0.0499065872091883	[]	[]	0	hSpCas9	negative selection	2768498
80005887	80005910	6	-	27260157	MKN45	viability	GTCTCTCACTTTGTTCATTATGG	TTK	ENSG00000112742	-0.903664219641247	[]	[]	-7	hSpCas9	negative selection	2771742
80010917	80010940	6	+	27260157	MKN45	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-1.48601417582327	[]	[]	-8	hSpCas9	negative selection	2773724
80007828	80007851	6	-	27260157	MKN45	viability	TGTTTGCCATCATCATAATTTGG	TTK	ENSG00000112742	-0.202481572452895	[]	[]	0	hSpCas9	negative selection	2774236
80010863	80010886	6	+	27260157	MKN45	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.79585545675195	[]	[]	-9	hSpCas9	negative selection	2775022
80005844	80005867	6	+	27260157	MKN45	viability	ATGGAATCCGAGGATTTAAGTGG	TTK	ENSG00000112742	-2.73306102405809	[]	[]	-9	hSpCas9	negative selection	2793243
80008396	80008419	6	-	27260157	MKN45	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-2.14977843081747	[]	[]	-9	hSpCas9	negative selection	2798659
80011739	80011762	6	-	27260157	MKN45	viability	CCTATTTCTGCATCTTGTGGTGG	TTK	ENSG00000112742	-2.92153087531181	[]	[]	-9	hSpCas9	negative selection	2799107
80007822	80007845	6	+	27260157	MKN45	viability	TGTTAACCAAATTATGATGATGG	TTK	ENSG00000112742	0.232157780300832	[]	[]	5	hSpCas9	negative selection	2800920
80011739	80011762	6	+	27260157	RKO	viability	CCACCACAAGATGCAGAAATAGG	TTK	ENSG00000112742	-1.60740480782644	[]	[]	-9	hSpCas9	negative selection	2802691
80007842	80007865	6	+	27260157	RKO	viability	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-1.8323205299028	[]	[]	-9	hSpCas9	negative selection	2804150
80013284	80013307	6	-	27260157	RKO	viability	ATCTCGGCATTCTGATCTAGAGG	TTK	ENSG00000112742	-2.84464036575106	[]	[]	-9	hSpCas9	negative selection	2806051
80007837	80007860	6	+	27260157	RKO	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-4.82567376533775	[]	[]	-9	hSpCas9	negative selection	2807406
80005834	80005857	6	+	27260157	RKO	viability	TTTCTTAGAAATGGAATCCGAGG	TTK	ENSG00000112742	-1.95730274512569	[]	[]	-9	hSpCas9	negative selection	2808478
80010877	80010900	6	+	27260157	RKO	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-1.94978993384108	[]	[]	-9	hSpCas9	negative selection	2812399
80005851	80005874	6	-	27260157	RKO	viability	TTCTCTGCCACTTAAATCCTCGG	TTK	ENSG00000112742	-1.25167659241204	[]	[]	-8	hSpCas9	negative selection	2816088
80011467	80011490	6	-	27260157	RKO	viability	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	-3.26010999783729	[]	[]	-9	hSpCas9	negative selection	2837615
80007852	80007875	6	-	27260157	RKO	viability	ACAAACTCAACCAGTCCTCTGGG	TTK	ENSG00000112742	-2.13966140429945	[]	[]	-9	hSpCas9	negative selection	2843146
80005936	80005959	6	-	27260157	RKO	viability	TCAAGCTTAGTTCATCAGTAAGG	TTK	ENSG00000112742	-2.41346603827583	[]	[]	-9	hSpCas9	negative selection	2844628
80005887	80005910	6	-	27260157	RKO	viability	GTCTCTCACTTTGTTCATTATGG	TTK	ENSG00000112742	-2.83742701163137	[]	[]	-9	hSpCas9	negative selection	2847872
80010917	80010940	6	+	27260157	RKO	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-2.74145495571111	[]	[]	-9	hSpCas9	negative selection	2849854
80007828	80007851	6	-	27260157	RKO	viability	TGTTTGCCATCATCATAATTTGG	TTK	ENSG00000112742	0.305613717093166	[]	[]	1	hSpCas9	negative selection	2850366
80010863	80010886	6	+	27260157	RKO	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-3.62006709384889	[]	[]	-9	hSpCas9	negative selection	2851152
80005844	80005867	6	+	27260157	RKO	viability	ATGGAATCCGAGGATTTAAGTGG	TTK	ENSG00000112742	-1.94556265588455	[]	[]	-9	hSpCas9	negative selection	2869373
80008396	80008419	6	-	27260157	RKO	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.449133118098311	[]	[]	-6	hSpCas9	negative selection	2874789
80011739	80011762	6	-	27260157	RKO	viability	CCTATTTCTGCATCTTGTGGTGG	TTK	ENSG00000112742	-1.98283036142756	[]	[]	-9	hSpCas9	negative selection	2875237
80007822	80007845	6	+	27260157	RKO	viability	TGTTAACCAAATTATGATGATGG	TTK	ENSG00000112742	-0.739164150744679	[]	[]	-7	hSpCas9	negative selection	2877050
80011739	80011762	6	+	27260157	SF268	viability	CCACCACAAGATGCAGAAATAGG	TTK	ENSG00000112742	-1.20812575732915	[]	[]	-7	hSpCas9	negative selection	2878821
80007842	80007865	6	+	27260157	SF268	viability	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-1.37418098947227	[]	[]	-7	hSpCas9	negative selection	2880280
80013284	80013307	6	-	27260157	SF268	viability	ATCTCGGCATTCTGATCTAGAGG	TTK	ENSG00000112742	-2.83385031661547	[]	[]	-9	hSpCas9	negative selection	2882181
80007837	80007860	6	+	27260157	SF268	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-3.91754192588622	[]	[]	-9	hSpCas9	negative selection	2883536
80005834	80005857	6	+	27260157	SF268	viability	TTTCTTAGAAATGGAATCCGAGG	TTK	ENSG00000112742	-0.353568771739717	[]	[]	-3	hSpCas9	negative selection	2884608
80010877	80010900	6	+	27260157	SF268	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-3.14156991530944	[]	[]	-9	hSpCas9	negative selection	2888529
80005851	80005874	6	-	27260157	SF268	viability	TTCTCTGCCACTTAAATCCTCGG	TTK	ENSG00000112742	-0.388998662148727	[]	[]	-3	hSpCas9	negative selection	2892218
80011467	80011490	6	-	27260157	SF268	viability	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	-1.98786011149427	[]	[]	-8	hSpCas9	negative selection	2913745
80007852	80007875	6	-	27260157	SF268	viability	ACAAACTCAACCAGTCCTCTGGG	TTK	ENSG00000112742	-1.17175616319132	[]	[]	-7	hSpCas9	negative selection	2919276
80005936	80005959	6	-	27260157	SF268	viability	TCAAGCTTAGTTCATCAGTAAGG	TTK	ENSG00000112742	0.0415138497268935	[]	[]	0	hSpCas9	negative selection	2920758
80005887	80005910	6	-	27260157	SF268	viability	GTCTCTCACTTTGTTCATTATGG	TTK	ENSG00000112742	-0.420662401782787	[]	[]	-3	hSpCas9	negative selection	2924002
80010917	80010940	6	+	27260157	SF268	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-2.88739730158676	[]	[]	-9	hSpCas9	negative selection	2925984
80007828	80007851	6	-	27260157	SF268	viability	TGTTTGCCATCATCATAATTTGG	TTK	ENSG00000112742	0.0364529418242516	[]	[]	0	hSpCas9	negative selection	2926496
80010863	80010886	6	+	27260157	SF268	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-2.90160472515324	[]	[]	-9	hSpCas9	negative selection	2927282
80005844	80005867	6	+	27260157	SF268	viability	ATGGAATCCGAGGATTTAAGTGG	TTK	ENSG00000112742	-0.161515472147675	[]	[]	-1	hSpCas9	negative selection	2945503
80008396	80008419	6	-	27260157	SF268	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.998506377321656	[]	[]	-7	hSpCas9	negative selection	2950919
80011739	80011762	6	-	27260157	SF268	viability	CCTATTTCTGCATCTTGTGGTGG	TTK	ENSG00000112742	-2.92229584245258	[]	[]	-9	hSpCas9	negative selection	2951367
80007822	80007845	6	+	27260157	SF268	viability	TGTTAACCAAATTATGATGATGG	TTK	ENSG00000112742	-0.157596999626706	[]	[]	-1	hSpCas9	negative selection	2953180
80014538	80014561	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATAACCCTGAAGAATAAAACGG	TTK	ENSG00000112742	-0.3945554433980399	[3,3]	[1,2]	-5	hSpCas9	positive selection	3030003
80007838	80007861	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	1.0522700442693498	[0,1]	[2,3]	9	hSpCas9	positive selection	3030004
80008472	80008495	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACAATTTGAACTGTCACAAGG	TTK	ENSG00000112742	0.1728939315000527	[3,4]	[3,3]	3	hSpCas9	positive selection	3030005
80010892	80010915	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGGAGGTTTAAATTCCGCAGGG	TTK	ENSG00000112742	-0.04379896146530754	[4,5]	[4,3]	0	hSpCas9	positive selection	3030006
80014538	80014561	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATAACCCTGAAGAATAAAACGG	TTK	ENSG00000112742	-0.09635414048409982	[3,3]	[3,1]	-1	hSpCas9	positive selection	3097861
80007838	80007861	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-0.08705159239646965	[0,0]	[0,0]	-1	hSpCas9	positive selection	3097862
80008472	80008495	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACAATTTGAACTGTCACAAGG	TTK	ENSG00000112742	-0.4331959910898533	[3,3]	[2,0]	-6	hSpCas9	positive selection	3097863
80010892	80010915	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGGAGGTTTAAATTCCGCAGGG	TTK	ENSG00000112742	-0.08996911436268873	[4,4]	[3,2]	-1	hSpCas9	positive selection	3097864
80008396	80008419		-	24336571	A375	resistance to PLX after 7 days	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	0.32176284613497774	[45,37]	[51,52]	8	hSpCas9	positive selection	3153398
80007958	80007981		+	24336571	A375	resistance to PLX after 7 days	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.4349244836956466	[4,7]	[10,7]	9	hSpCas9	positive selection	3153399
80008404	80008427		+	24336571	A375	resistance to PLX after 7 days	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.33621875206176755	[14,14]	[15,21]	8	hSpCas9	positive selection	3153400
80008396	80008419		-	24336571	A375	resistance to PLX after 14 days	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	0.03661781916862328	[47,40]	[20,20]	0	hSpCas9	positive selection	3211191
80007958	80007981		+	24336571	A375	resistance to PLX after 14 days	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.29748758528984676	[9,6]	[2,2]	-3	hSpCas9	positive selection	3211192
80008404	80008427		+	24336571	A375	resistance to PLX after 14 days	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.5512156145232311	[15,14]	[8,11]	5	hSpCas9	positive selection	3211193
80008396	80008419		-	24336571	A375	viability after 7 days	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	0.07727150516622716	[41]	[45,37]	1	hSpCas9	negative selection	3268984
80007958	80007981		+	24336571	A375	viability after 7 days	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.25558378371270274	[8]	[4,7]	-4	hSpCas9	negative selection	3268985
80008404	80008427		+	24336571	A375	viability after 7 days	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.6676846865267826	[25]	[14,14]	-7	hSpCas9	negative selection	3268986
80008396	80008419		-	24336571	A375	viability after 14 days	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	0.17535940980280573	[41]	[47,40]	2	hSpCas9	negative selection	3326777
80007958	80007981		+	24336571	A375	viability after 14 days	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.09577801264645291	[8]	[9,6]	1	hSpCas9	negative selection	3326778
80008404	80008427		+	24336571	A375	viability after 14 days	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.6226395979809881	[25]	[15,14]	-6	hSpCas9	negative selection	3326779
80010840	80010863	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	-0.01879819382840228	[154,154]	[0,0]	0	hSpCas9	positive selection	3399606
80010863	80010886	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	1.449971289388231	[55,55]	[0,0]	6	hSpCas9	positive selection	3399607
80007853	80007876	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	1.3746831620839939	[58,58]	[0,0]	6	hSpCas9	positive selection	3399608
80014537	80014560	6	+	26780180	HT29	viability (Avana library 4 designs)	AATAACCCTGAAGAATAAAACGG	TTK	ENSG00000112742	2.53461874297604	[]	[]	8	hSpCas9	negative selection	3468917
80007837	80007860	6	+	26780180	HT29	viability (Avana library 4 designs)	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	2.87661676385321	[]	[]	8	hSpCas9	negative selection	3468918
80008471	80008494	6	+	26780180	HT29	viability (Avana library 4 designs)	GCACAATTTGAACTGTCACAAGG	TTK	ENSG00000112742	4.61600841095124	[]	[]	9	hSpCas9	negative selection	3468919
80010892	80010915	6	-	26780180	HT29	viability (Avana library 4 designs)	TTGGAGGTTTAAATTCCGCAGGG	TTK	ENSG00000112742	3.82302451955044	[]	[]	9	hSpCas9	negative selection	3468920
80007837	80007860	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-14.4119379784448	[]	[]	-8	hSpCas9	negative selection	3573894
80010892	80010915	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGGAGGTTTAAATTCCGCAGGG	TTK	ENSG00000112742	-0.644505240790742	[]	[]	-1	hSpCas9	negative selection	3573895
80014537	80014560	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATAACCCTGAAGAATAAAACGG	TTK	ENSG00000112742	-19.2644329040218	[]	[]	-9	hSpCas9	negative selection	3573896
80008471	80008494	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACAATTTGAACTGTCACAAGG	TTK	ENSG00000112742	-3.90466686135642	[]	[]	-4	hSpCas9	negative selection	3573897
80022354	80022377	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-5.02146234239045	[]	[]	-5	hSpCas9	negative selection	3573898
80010870	80010893	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAATTTCCAGCATTTCTAGTGG	TTK	ENSG00000112742	-19.0440585821096	[]	[]	-9	hSpCas9	negative selection	3573899
80007837	80007860	6	+	26780180	A375	viability (Avana lentiGuide)	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	22.0331694874655	[]	[]	9	hSpCas9	negative selection	3682553
80010892	80010915	6	-	26780180	A375	viability (Avana lentiGuide)	TTGGAGGTTTAAATTCCGCAGGG	TTK	ENSG00000112742	10.5346128645943	[]	[]	7	hSpCas9	negative selection	3682554
80014537	80014560	6	+	26780180	A375	viability (Avana lentiGuide)	AATAACCCTGAAGAATAAAACGG	TTK	ENSG00000112742	8.81400093910937	[]	[]	6	hSpCas9	negative selection	3682555
80008471	80008494	6	+	26780180	A375	viability (Avana lentiGuide)	GCACAATTTGAACTGTCACAAGG	TTK	ENSG00000112742	13.874672767432	[]	[]	7	hSpCas9	negative selection	3682556
80022354	80022377	6	+	26780180	A375	viability (Avana lentiGuide)	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	11.2414775886537	[]	[]	7	hSpCas9	negative selection	3682557
80010870	80010893	6	-	26780180	A375	viability (Avana lentiGuide)	GCAATTTCCAGCATTTCTAGTGG	TTK	ENSG00000112742	12.9189045969758	[]	[]	7	hSpCas9	negative selection	3682558
80007837	80007860	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-1.9626179063501985	[4]	[0,0]	-9	hSpCas9	positive selection	3791160
80010892	80010915	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGGAGGTTTAAATTCCGCAGGG	TTK	ENSG00000112742	-0.05228737835306868	[6]	[7,5]	-1	hSpCas9	positive selection	3791161
80014537	80014560	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATAACCCTGAAGAATAAAACGG	TTK	ENSG00000112742	-1.0256080096236282	[9]	[4,3]	-9	hSpCas9	positive selection	3791162
80008471	80008494	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACAATTTGAACTGTCACAAGG	TTK	ENSG00000112742	0.05154567895614842	[5]	[6,5]	1	hSpCas9	positive selection	3791163
80022354	80022377	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-0.5567100666690314	[4]	[3,2]	-7	hSpCas9	positive selection	3791164
80010870	80010893	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAATTTCCAGCATTTCTAGTGG	TTK	ENSG00000112742	-0.9598524454671943	[5]	[2,1]	-8	hSpCas9	positive selection	3791165
80007837	80007860	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-0.9935461996302345	[3]	[1,0]	-8	hSpCas9	positive selection	3899767
80010892	80010915	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGGAGGTTTAAATTCCGCAGGG	TTK	ENSG00000112742	-0.1480851070442297	[7]	[6,3]	-2	hSpCas9	positive selection	3899768
80014537	80014560	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATAACCCTGAAGAATAAAACGG	TTK	ENSG00000112742	-0.5508835682437587	[5]	[3,1]	-6	hSpCas9	positive selection	3899769
80008471	80008494	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACAATTTGAACTGTCACAAGG	TTK	ENSG00000112742	-0.10454048186081653	[6]	[4,4]	-1	hSpCas9	positive selection	3899770
80022354	80022377	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-0.2240341050192353	[5]	[3,3]	-3	hSpCas9	positive selection	3899771
80010870	80010893	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAATTTCCAGCATTTCTAGTGG	TTK	ENSG00000112742	-0.6279694399373477	[5]	[3,2]	-7	hSpCas9	positive selection	3899772
80007853	80007876	6	-	26780180	A375	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	1.59147451471459	[]	[]	8	hSpCas9	negative selection	4008898
80008396	80008419	6	-	26780180	A375	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	1.43645302904373	[]	[]	8	hSpCas9	negative selection	4008899
80010863	80010886	6	+	26780180	A375	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	1.61497484401899	[]	[]	8	hSpCas9	negative selection	4008900
80010840	80010863	6	+	26780180	A375	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	1.38021454294584	[]	[]	7	hSpCas9	negative selection	4008901
80007958	80007981	6	+	26780180	A375	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.654432624980133	[]	[]	2	hSpCas9	negative selection	4008902
80008404	80008427	6	+	26780180	A375	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	1.52420778791283	[]	[]	8	hSpCas9	negative selection	4008903
80007853	80007876	6	-	26780180	HT29	viability (GeCKOv2 library)	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	2.22413305022086	[]	[]	9	hSpCas9	negative selection	4116864
80008396	80008419	6	-	26780180	HT29	viability (GeCKOv2 library)	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	1.74626983114755	[]	[]	8	hSpCas9	negative selection	4116865
80010863	80010886	6	+	26780180	HT29	viability (GeCKOv2 library)	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	2.06461035417929	[]	[]	9	hSpCas9	negative selection	4116866
80010840	80010863	6	+	26780180	HT29	viability (GeCKOv2 library)	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.298474220572032	[]	[]	0	hSpCas9	negative selection	4116867
80007958	80007981	6	+	26780180	HT29	viability (GeCKOv2 library)	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.723809833066405	[]	[]	2	hSpCas9	negative selection	4116868
80008404	80008427	6	+	26780180	HT29	viability (GeCKOv2 library)	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.494132965032768	[]	[]	1	hSpCas9	negative selection	4116869
80008396	80008419	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	0.19488005033437816	[5]	[4,4]	5	hSpCas9	positive selection	4180030
80007958	80007981	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.03429034217593707	[3]	[2,1]	-1	hSpCas9	positive selection	4180031
80008404	80008427	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.5571922125771178	[4]	[5,3]	9	hSpCas9	positive selection	4180032
80008396	80008419	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	1.1647341806148805	[5]	[6,6,4,4]	8	hSpCas9	positive selection	4244052
80007958	80007981	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.7824321207121885	[1]	[3,1,0,0]	5	hSpCas9	positive selection	4244053
80008404	80008427	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.09004233723974632	[4]	[1,3,1,0]	-1	hSpCas9	positive selection	4244054
80008396	80008419	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.2338715335745884	[4]	[3,2]	-5	hSpCas9	positive selection	4305799
80007958	80007981	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.2270701365629776	[1]	[2,0]	4	hSpCas9	positive selection	4305800
80008404	80008427	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.09976374551199235	[3]	[3,2]	2	hSpCas9	positive selection	4305801
80010840	80010863	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.356550206528492	[2]	[4,2]	7	hSpCas9	positive selection	4370048
80010863	80010886	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.7353411875849998	[2]	[1,0]	-9	hSpCas9	positive selection	4370049
80007853	80007876	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.6400047528151411	[2]	[1,0]	-9	hSpCas9	positive selection	4370050
80007959	80007981	6	+	27760321	OCIAML3	viability	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.03637583274201939	[90,81]	[44,100]	0	hSpCas9	negative selection	4451074
80008405	80008427	6	+	27760321	OCIAML3	viability	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.028840970937710875	[167,108]	[68,160]	0	hSpCas9	negative selection	4451075
80010893	80010915	6	-	27760321	OCIAML3	viability	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-0.5925542517696931	[435,324]	[100,318]	-5	hSpCas9	negative selection	4451076
80013299	80013321	6	+	27760321	OCIAML3	viability	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	0.5819775888906311	[1052,774]	[843,1341]	7	hSpCas9	negative selection	4451077
80022452	80022474	6	+	27760321	OCIAML3	viability	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.5670304976997644	[101,56]	[20,19]	-8	hSpCas9	negative selection	4451078
80007959	80007981	6	+	27760321	OCIAML2	viability	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.5401442003637982	[90,81]	[57,34]	-6	hSpCas9	negative selection	4534537
80008405	80008427	6	+	27760321	OCIAML2	viability	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.2637572472086669	[167,108]	[50,145]	-3	hSpCas9	negative selection	4534538
80010893	80010915	6	-	27760321	OCIAML2	viability	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-0.90755700718692	[435,324]	[169,152]	-7	hSpCas9	negative selection	4534539
80013299	80013321	6	+	27760321	OCIAML2	viability	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	0.8155506812169966	[1052,774]	[1073,1572]	9	hSpCas9	negative selection	4534540
80022452	80022474	6	+	27760321	OCIAML2	viability	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-0.5088992336844518	[101,56]	[42,45]	-5	hSpCas9	negative selection	4534541
80007959	80007981	6	+	27760321	MV411	viability	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-3.512555113931533	[90,81]	[0,10]	-9	hSpCas9	negative selection	4618000
80008405	80008427	6	+	27760321	MV411	viability	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.5035591552927605	[167,108]	[5,149]	-4	hSpCas9	negative selection	4618001
80010893	80010915	6	-	27760321	MV411	viability	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-0.1808559059364518	[435,324]	[199,248]	-1	hSpCas9	negative selection	4618002
80013299	80013321	6	+	27760321	MV411	viability	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	0.6479962092041882	[1052,774]	[736,1235]	5	hSpCas9	negative selection	4618003
80022452	80022474	6	+	27760321	MV411	viability	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	0.042611870693900045	[101,56]	[0,130]	0	hSpCas9	negative selection	4618004
80007959	80007981	6	+	27760321	HL60	viability	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.7371487307993829	[90,81]	[89,146]	8	hSpCas9	negative selection	4701463
80008405	80008427	6	+	27760321	HL60	viability	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.39340153745864326	[167,108]	[81,87]	-4	hSpCas9	negative selection	4701464
80010893	80010915	6	-	27760321	HL60	viability	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	0.1311665674761432	[435,324]	[401,268]	1	hSpCas9	negative selection	4701465
80013299	80013321	6	+	27760321	HL60	viability	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	0.5542947570884784	[1052,774]	[1062,1110]	6	hSpCas9	negative selection	4701466
80022452	80022474	6	+	27760321	HL60	viability	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-3.172627124157294	[101,56]	[8,4]	-9	hSpCas9	negative selection	4701467
80007959	80007981	6	+	27760321	HT1080	viability	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-3.321284820369203	[81,63]	[0,4]	-7	hSpCas9	negative selection	4784926
80008405	80008427	6	+	27760321	HT1080	viability	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-5.272021730492227	[108,84]	[0,0]	-8	hSpCas9	negative selection	4784927
80010893	80010915	6	-	27760321	HT1080	viability	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-4.337793710789267	[324,253]	[9,0]	-8	hSpCas9	negative selection	4784928
80013299	80013321	6	+	27760321	HT1080	viability	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	0.1673093196653065	[774,604]	[322,292]	0	hSpCas9	negative selection	4784929
80022452	80022474	6	+	27760321	HT1080	viability	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-4.345633619488636	[56,44]	[0,0]	-8	hSpCas9	negative selection	4784930
80007959	80007981	6	+	27760321	HT29	viability after 7 days	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-1.452827997514604	[81,63]	[30,57,13]	-9	hSpCas9	negative selection	4868389
80008405	80008427	6	+	27760321	HT29	viability after 7 days	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.429401878821426	[108,84]	[361,56,113]	6	hSpCas9	negative selection	4868390
80010893	80010915	6	-	27760321	HT29	viability after 7 days	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-0.5064268376339153	[324,253]	[219,177,377]	-6	hSpCas9	negative selection	4868391
80013299	80013321	6	+	27760321	HT29	viability after 7 days	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	0.5474789377891357	[774,604]	[1284,1454,1150]	8	hSpCas9	negative selection	4868392
80022452	80022474	6	+	27760321	HT29	viability after 7 days	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	0.22811351353361298	[56,44]	[121,72,42]	3	hSpCas9	negative selection	4868393
80007959	80007981	6	+	27760321	HT29	viability after 25 days	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-1.033238345630123	[81,63]	[66,34,15]	-6	hSpCas9	negative selection	4951852
80008405	80008427	6	+	27760321	HT29	viability after 25 days	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-2.09729613735017	[108,84]	[10,46,19]	-8	hSpCas9	negative selection	4951853
80010893	80010915	6	-	27760321	HT29	viability after 25 days	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-1.477286415867665	[324,253]	[71,213,67]	-7	hSpCas9	negative selection	4951854
80013299	80013321	6	+	27760321	HT29	viability after 25 days	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	0.9745050716283202	[774,604]	[928,1570,2258]	9	hSpCas9	negative selection	4951855
80022452	80022474	6	+	27760321	HT29	viability after 25 days	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.2007075360695842	[56,44]	[8,60,4]	-7	hSpCas9	negative selection	4951856
80007959	80007981	6	+	27760321	HT29	viability after 22 days	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.28031949288570024	[81,63]	[143,39,21]	-3	hSpCas9	negative selection	5035315
80008405	80008427	6	+	27760321	HT29	viability after 22 days	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.3151887523121899	[108,84]	[137,48,81]	-3	hSpCas9	negative selection	5035316
80010893	80010915	6	-	27760321	HT29	viability after 22 days	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-0.8921940427958935	[324,253]	[263,171,101]	-6	hSpCas9	negative selection	5035317
80013299	80013321	6	+	27760321	HT29	viability after 22 days	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	1.021365811156072	[774,604]	[1275,1629,1963]	9	hSpCas9	negative selection	5035318
80022452	80022474	6	+	27760321	HT29	viability after 22 days	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	0.1390726943390419	[56,44]	[10,158,25]	1	hSpCas9	negative selection	5035319
80007959	80007981	6	+	27760321	HT29	viability after 19 days	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-1.9743304933909123	[81,63]	[3,11,44]	-8	hSpCas9	negative selection	5118778
80008405	80008427	6	+	27760321	HT29	viability after 19 days	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.7714832115737913	[108,84]	[33,47,107]	-6	hSpCas9	negative selection	5118779
80010893	80010915	6	-	27760321	HT29	viability after 19 days	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-0.9030586880214538	[324,253]	[233,97,203]	-6	hSpCas9	negative selection	5118780
80013299	80013321	6	+	27760321	HT29	viability after 19 days	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	0.986396031726846	[774,604]	[1845,1122,1742]	8	hSpCas9	negative selection	5118781
80022452	80022474	6	+	27760321	HT29	viability after 19 days	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	1.1271652540856465	[56,44]	[102,126,148]	9	hSpCas9	negative selection	5118782
80007959	80007981	6	+	27760321	HT29	viability after 16 days	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-2.2490293341589718	[81,63]	[14,29,5]	-8	hSpCas9	negative selection	5202241
80008405	80008427	6	+	27760321	HT29	viability after 16 days	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.6091359372218381	[108,84]	[93,54,66]	-5	hSpCas9	negative selection	5202242
80010893	80010915	6	-	27760321	HT29	viability after 16 days	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-0.10378088188052353	[324,253]	[257,345,294]	-1	hSpCas9	negative selection	5202243
80013299	80013321	6	+	27760321	HT29	viability after 16 days	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	1.0901792674750932	[774,604]	[1406,1454,2050]	9	hSpCas9	negative selection	5202244
80022452	80022474	6	+	27760321	HT29	viability after 16 days	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-0.20407147691554428	[56,44]	[44,97,3]	-2	hSpCas9	negative selection	5202245
80007959	80007981	6	+	27760321	HT29	viability after 13 days	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-1.1750343697065038	[81,63]	[1,79,30]	-8	hSpCas9	negative selection	5285704
80008405	80008427	6	+	27760321	HT29	viability after 13 days	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.7654288181048079	[108,84]	[74,81,42]	-7	hSpCas9	negative selection	5285705
80010893	80010915	6	-	27760321	HT29	viability after 13 days	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-1.83478875173037	[324,253]	[78,117,85]	-8	hSpCas9	negative selection	5285706
80013299	80013321	6	+	27760321	HT29	viability after 13 days	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	0.9385806849106116	[774,604]	[1492,1463,1638]	9	hSpCas9	negative selection	5285707
80022452	80022474	6	+	27760321	HT29	viability after 13 days	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-0.3458674090701819	[56,44]	[6,122,11]	-4	hSpCas9	negative selection	5285708
80007959	80007981	6	+	27760321	HT29	viability after 10 days	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.992366842688758	[81,63]	[5,94,37]	-8	hSpCas9	negative selection	5369167
80008405	80008427	6	+	27760321	HT29	viability after 10 days	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.7243280101747505	[108,84]	[163,151,280]	8	hSpCas9	negative selection	5369168
80010893	80010915	6	-	27760321	HT29	viability after 10 days	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-0.8538665420469173	[324,253]	[197,240,162]	-7	hSpCas9	negative selection	5369169
80013299	80013321	6	+	27760321	HT29	viability after 10 days	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	0.769905800920459	[774,604]	[1394,1605,1410]	9	hSpCas9	negative selection	5369170
80022452	80022474	6	+	27760321	HT29	viability after 10 days	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	0.3274477692616906	[56,44]	[16,130,92]	4	hSpCas9	negative selection	5369171
80007959	80007981	6	+	27760321	MOLM13	viability	CGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-1.8038436471387693	[90,81]	[0,24]	-7	hSpCas9	negative selection	5452630
80008405	80008427	6	+	27760321	MOLM13	viability	GCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-1.9560582016263885	[167,108]	[41,0]	-8	hSpCas9	negative selection	5452631
80010893	80010915	6	-	27760321	MOLM13	viability	TTGGAGGTTTAAATTCCGCAGG	TTK	ENSG00000112742	-0.7767092819431973	[435,324]	[201,57]	-5	hSpCas9	negative selection	5452632
80013299	80013321	6	+	27760321	MOLM13	viability	GCCGAGATTTGGTTGTGCCTGG	TTK	ENSG00000112742	0.3610917674624494	[1052,774]	[800,532]	2	hSpCas9	negative selection	5452633
80022452	80022474	6	+	27760321	MOLM13	viability	GCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.223476556752492	[101,56]	[0,33]	-6	hSpCas9	negative selection	5452634
80004749	80004772	6	+	27661255	K562	viability	GGAACAGCCGCAGCCGGTGTAGG	TTK	ENSG00000112742	-3.907979558522296	[1175,1413]	[99,41]	-9	dCas9-KRAB	negative selection	5520526
80004942	80004965	6	+	27661255	K562	viability	GTGGCCCACGCTGGAAAGAAGGG	TTK	ENSG00000112742	-0.9309904161185347	[745,805]	[362,291]	-8	dCas9-KRAB	negative selection	5520527
80004679	80004702	6	-	27661255	K562	viability	GCGCTGGGGAAATGAAAAGATGG	TTK	ENSG00000112742	-2.156795717962911	[144,145]	[31,20]	-9	dCas9-KRAB	negative selection	5520528
80008396	80008419	6	-	27260156	BXPC3	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.3702130721617374	[1895]	[1463,1456,1583,1645]	-7	hSpCas9	negative selection	5578259
80007958	80007981	6	+	27260156	BXPC3	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.2521987846170477	[141]	[161,142,192,216]	5	hSpCas9	negative selection	5578260
80008404	80008427	6	+	27260156	BXPC3	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.2818228864079093	[885]	[548,808,817,905]	-6	hSpCas9	negative selection	5578261
80010840	80010863	6	+	27260156	BXPC3	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.18536950227626484	[419]	[505,510,466,508]	4	hSpCas9	negative selection	5642508
80010863	80010886	6	+	27260156	BXPC3	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.7297474485713683	[312]	[156,184,181,278]	-9	hSpCas9	negative selection	5642509
80007853	80007876	6	-	27260156	BXPC3	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.26890731434136833	[377]	[337,333,306,328]	-6	hSpCas9	negative selection	5642510
80008396	80008419	6	-	27260156	A673	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.2764034399083528	[1895]	[2045,1692,1825,1979]	-6	hSpCas9	negative selection	5699510
80007958	80007981	6	+	27260156	A673	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.003236109728791403	[141]	[186,143,132,221]	0	hSpCas9	negative selection	5699511
80008404	80008427	6	+	27260156	A673	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.2588578759189696	[885]	[1015,807,824,924]	-6	hSpCas9	negative selection	5699512
80010840	80010863	6	+	27260156	A673	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.051094644044827386	[419]	[579,458,492,567]	1	hSpCas9	negative selection	5763759
80010863	80010886	6	+	27260156	A673	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.9585940836051704	[312]	[146,181,268,167]	-9	hSpCas9	negative selection	5763760
80007853	80007876	6	-	27260156	A673	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.21046420803049687	[377]	[459,317,376,424]	-5	hSpCas9	negative selection	5763761
80008396	80008419	6	-	27260156	A375	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.2185291291103626	[1895]	[1750,2231,1845,1829]	-3	hSpCas9	negative selection	5820761
80007958	80007981	6	+	27260156	A375	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.282643404229419	[141]	[237,192,280,104]	4	hSpCas9	negative selection	5820762
80008404	80008427	6	+	27260156	A375	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.869413741655571	[885]	[570,608,536,553]	-8	hSpCas9	negative selection	5820763
80010840	80010863	6	+	27260156	A375	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	-0.06650857517527825	[419]	[507,606,413,373]	-1	hSpCas9	negative selection	5885010
80010863	80010886	6	+	27260156	A375	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.4875087362651698	[312]	[112,225,90,106]	-9	hSpCas9	negative selection	5885011
80007853	80007876	6	-	27260156	A375	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.7928398008573507	[377]	[431,128,147,288]	-7	hSpCas9	negative selection	5885012
80008396	80008419	6	-	27260156	COLO741	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.2980118644404517	[1895]	[1923,1534,2409]	-6	hSpCas9	negative selection	5942012
80007958	80007981	6	+	27260156	COLO741	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.30301731981029056	[141]	[122,100,209]	-6	hSpCas9	negative selection	5942013
80008404	80008427	6	+	27260156	COLO741	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.0018649686172924618	[885]	[1279,1022,1108]	0	hSpCas9	negative selection	5942014
80010840	80010863	6	+	27260156	COLO741	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	-0.19380209667260126	[419]	[321,542,524]	-4	hSpCas9	negative selection	6006261
80010863	80010886	6	+	27260156	COLO741	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.6717862533900084	[312]	[136,199,394]	-8	hSpCas9	negative selection	6006262
80007853	80007876	6	-	27260156	COLO741	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.918248084388871	[377]	[338,205,229]	-9	hSpCas9	negative selection	6006263
80008396	80008419	6	-	27260156	CAL120	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.15986891059340014	[1895]	[2440,1983,1961]	-2	hSpCas9	negative selection	6063263
80007958	80007981	6	+	27260156	CAL120	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.6572733031135962	[141]	[297,215,323]	8	hSpCas9	negative selection	6063264
80008404	80008427	6	+	27260156	CAL120	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.17862340539217547	[885]	[1023,1238,671]	-3	hSpCas9	negative selection	6063265
80010840	80010863	6	+	27260156	CAL120	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.5339927527004039	[419]	[1207,717,417]	7	hSpCas9	negative selection	6127512
80010863	80010886	6	+	27260156	CAL120	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.074169638626521	[312]	[102,111,324]	-8	hSpCas9	negative selection	6127513
80007853	80007876	6	-	27260156	CAL120	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.7877497351969609	[377]	[274,288,253]	-8	hSpCas9	negative selection	6127514
80008396	80008419	6	-	27260156	CADOES1	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.2900400862089223	[1895]	[1305,1171,1482,1821]	-5	hSpCas9	negative selection	6184514
80007958	80007981	6	+	27260156	CADOES1	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.0003685296251632053	[141]	[125,129,99,173]	0	hSpCas9	negative selection	6184515
80008404	80008427	6	+	27260156	CADOES1	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.0723387380182543	[885]	[837,906,873,845]	1	hSpCas9	negative selection	6184516
80010840	80010863	6	+	27260156	CADOES1	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.2191386080171449	[419]	[417,461,379,562]	4	hSpCas9	negative selection	6248763
80010863	80010886	6	+	27260156	CADOES1	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.4622893181438053	[312]	[136,128,90,63]	-9	hSpCas9	negative selection	6248764
80007853	80007876	6	-	27260156	CADOES1	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.34370634058225374	[377]	[275,306,380,138]	-5	hSpCas9	negative selection	6248765
80008396	80008419	6	-	27260156	EWS502	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.1699176043550037	[1895]	[1946,1552,1660,1973]	-3	hSpCas9	negative selection	6305765
80007958	80007981	6	+	27260156	EWS502	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.08795744404637507	[141]	[90,146,161,173]	-1	hSpCas9	negative selection	6305766
80008404	80008427	6	+	27260156	EWS502	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.3566095714134624	[885]	[687,867,773,588]	-6	hSpCas9	negative selection	6305767
80010840	80010863	6	+	27260156	EWS502	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.3818239909563231	[419]	[597,523,692,496]	6	hSpCas9	negative selection	6370014
80010863	80010886	6	+	27260156	EWS502	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.9253478111494693	[312]	[61,99,94,94]	-9	hSpCas9	negative selection	6370015
80007853	80007876	6	-	27260156	EWS502	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.6989129167630235	[377]	[241,281,217,241]	-8	hSpCas9	negative selection	6370016
80008396	80008419	6	-	27260156	EW8	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.123818991206053	[1895]	[1682,1400,1249,1359]	-2	hSpCas9	negative selection	6427016
80007958	80007981	6	+	27260156	EW8	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.3272320267421971	[141]	[109,108,149,202]	6	hSpCas9	negative selection	6427017
80008404	80008427	6	+	27260156	EW8	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.3392499496842446	[885]	[542,619,532,575]	-6	hSpCas9	negative selection	6427018
80010840	80010863	6	+	27260156	EW8	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.5827242059728673	[419]	[690,464,453,456]	8	hSpCas9	negative selection	6491265
80010863	80010886	6	+	27260156	EW8	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.8400780273108873	[312]	[106,174,139,140]	-9	hSpCas9	negative selection	6491266
80007853	80007876	6	-	27260156	EW8	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.5751644147992896	[377]	[271,188,194,174]	-8	hSpCas9	negative selection	6491267
80008396	80008419	6	-	27260156	CORL105	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.6457682863335577	[1895]	[1177,1307,1745,1486]	-8	hSpCas9	negative selection	6548267
80007958	80007981	6	+	27260156	CORL105	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.11451603229386564	[141]	[223,132,190,175]	2	hSpCas9	negative selection	6548268
80008404	80008427	6	+	27260156	CORL105	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.656108974723129	[885]	[617,855,526,605]	-8	hSpCas9	negative selection	6548269
80010840	80010863	6	+	27260156	CORL105	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	-0.532944152739766	[419]	[337,296,484,262]	-7	hSpCas9	negative selection	6612516
80010863	80010886	6	+	27260156	CORL105	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.363227319760151	[312]	[97,161,131,173]	-9	hSpCas9	negative selection	6612517
80007853	80007876	6	-	27260156	CORL105	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.48595432283701506	[377]	[433,314,338,183]	-7	hSpCas9	negative selection	6612518
80008396	80008419	6	-	27260156	HS294T	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	0.0025046988226327116	[1895]	[531,1004,615,803]	0	hSpCas9	negative selection	6669518
80007958	80007981	6	+	27260156	HS294T	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.3075168352353259	[141]	[43,74,54,105]	4	hSpCas9	negative selection	6669519
80008404	80008427	6	+	27260156	HS294T	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.20403833804554772	[885]	[201,606,357,426]	2	hSpCas9	negative selection	6669520
80010840	80010863	6	+	27260156	HS294T	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	-0.2463729969653927	[419]	[110,146,145,146]	-3	hSpCas9	negative selection	6733767
80010863	80010886	6	+	27260156	HS294T	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.7114735791317394	[312]	[119,41,60,67]	-7	hSpCas9	negative selection	6733768
80007853	80007876	6	-	27260156	HS294T	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.5399467215608404	[377]	[66,122,89,128]	-6	hSpCas9	negative selection	6733769
80008396	80008419	6	-	27260156	HCC44	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.13084174002103421	[1895]	[2430,1200,2553,1887]	-2	hSpCas9	negative selection	6790769
80007958	80007981	6	+	27260156	HCC44	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.5891590367565471	[141]	[423,108,268,203]	8	hSpCas9	negative selection	6790770
80008404	80008427	6	+	27260156	HCC44	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.11905875693619128	[885]	[835,655,1127,1121]	-2	hSpCas9	negative selection	6790771
80010840	80010863	6	+	27260156	HCC44	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.37218605539445637	[419]	[757,691,511,480]	6	hSpCas9	negative selection	6855018
80010863	80010886	6	+	27260156	HCC44	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-2.0713343181107637	[312]	[226,8,96,30]	-9	hSpCas9	negative selection	6855019
80007853	80007876	6	-	27260156	HCC44	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.7209510662443497	[377]	[421,200,197,227]	-8	hSpCas9	negative selection	6855020
80008396	80008419	6	-	27260156	G402	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	0.017978171812234045	[1895]	[2339,2850,1641,2546]	0	hSpCas9	negative selection	6912020
80007958	80007981	6	+	27260156	G402	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.40282319549408596	[141]	[193,114,201,384]	5	hSpCas9	negative selection	6912021
80008404	80008427	6	+	27260156	G402	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.703373019832937	[885]	[854,948,412,488]	-7	hSpCas9	negative selection	6912022
80010840	80010863	6	+	27260156	G402	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.5471266332558441	[419]	[657,1042,707,594]	6	hSpCas9	negative selection	6976269
80010863	80010886	6	+	27260156	G402	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.1533858431420039	[312]	[131,223,103,220]	-8	hSpCas9	negative selection	6976270
80007853	80007876	6	-	27260156	G402	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.22534866114440139	[377]	[462,307,511,302]	-3	hSpCas9	negative selection	6976271
80008396	80008419	6	-	27260156	L33	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.20363163381253258	[1895]	[1672,715,974,1612]	-5	hSpCas9	negative selection	7033271
80007958	80007981	6	+	27260156	L33	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.2877230979559906	[141]	[224,83,56,170]	6	hSpCas9	negative selection	7033272
80008404	80008427	6	+	27260156	L33	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.3374701341201891	[885]	[1036,500,700,1104]	7	hSpCas9	negative selection	7033273
80010840	80010863	6	+	27260156	L33	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.13645150062469172	[419]	[414,197,280,501]	3	hSpCas9	negative selection	7097520
80010863	80010886	6	+	27260156	L33	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.23237646885245267	[312]	[221,136,180,222]	-5	hSpCas9	negative selection	7097521
80007853	80007876	6	-	27260156	L33	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.2827351871895842	[377]	[263,170,194,252]	-6	hSpCas9	negative selection	7097522
80008396	80008419	6	-	27260156	K562	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	0.15840689052306756	[1895]	[2960,1737,1699,1258]	2	hSpCas9	negative selection	7154522
80007958	80007981	6	+	27260156	K562	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.20098922102710248	[141]	[163,141,183,95]	2	hSpCas9	negative selection	7154523
80008404	80008427	6	+	27260156	K562	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.5510310186154341	[885]	[1574,1333,1093,697]	7	hSpCas9	negative selection	7154524
80010840	80010863	6	+	27260156	K562	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.36459042929238117	[419]	[786,393,445,328]	4	hSpCas9	negative selection	7218771
80010863	80010886	6	+	27260156	K562	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.2182793370393465	[312]	[123,79,129,138]	-8	hSpCas9	negative selection	7218772
80007853	80007876	6	-	27260156	K562	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.3524858592630183	[377]	[336,207,263,245]	-4	hSpCas9	negative selection	7218773
80008396	80008419	6	-	27260156	HT29	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.203977397343996	[1895]	[2238,2106,2113,1605]	-4	hSpCas9	negative selection	7275773
80007958	80007981	6	+	27260156	HT29	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.6132012005395278	[141]	[298,348,221,201]	9	hSpCas9	negative selection	7275774
80008404	80008427	6	+	27260156	HT29	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.01566069545388793	[885]	[1039,1023,1115,1067]	0	hSpCas9	negative selection	7275775
80010840	80010863	6	+	27260156	HT29	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.05791371110323815	[419]	[502,736,388,510]	1	hSpCas9	negative selection	7340022
80010863	80010886	6	+	27260156	HT29	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.3296359621538416	[312]	[183,171,103,148]	-9	hSpCas9	negative selection	7340023
80007853	80007876	6	-	27260156	HT29	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.8095427798504466	[377]	[258,243,279,261]	-8	hSpCas9	negative selection	7340024
80008396	80008419	6	-	27260156	MHHES1	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.2765340113514012	[1895]	[1739,2085,2003,1317]	-5	hSpCas9	negative selection	7397024
80007958	80007981	6	+	27260156	MHHES1	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.16779861696082765	[141]	[196,113,319,98]	3	hSpCas9	negative selection	7397025
80008404	80008427	6	+	27260156	MHHES1	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.731243969240451	[885]	[1047,397,474,520]	-8	hSpCas9	negative selection	7397026
80010840	80010863	6	+	27260156	MHHES1	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	-0.21683549250233877	[419]	[378,415,635,228]	-4	hSpCas9	negative selection	7461273
80010863	80010886	6	+	27260156	MHHES1	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.2159265193874256	[312]	[123,199,149,134]	-9	hSpCas9	negative selection	7461274
80007853	80007876	6	-	27260156	MHHES1	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.8000539011066576	[377]	[284,263,241,198]	-9	hSpCas9	negative selection	7461275
80008396	80008419	6	-	27260156	MEWO	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.17655693112241488	[1895]	[1648,1478,1595]	-4	hSpCas9	negative selection	7518275
80007958	80007981	6	+	27260156	MEWO	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.6903683241619805	[141]	[233,191,220]	9	hSpCas9	negative selection	7518276
80008404	80008427	6	+	27260156	MEWO	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.066290117404611	[885]	[974,910,737]	1	hSpCas9	negative selection	7518277
80010840	80010863	6	+	27260156	MEWO	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.16714054991678498	[419]	[565,375,405]	3	hSpCas9	negative selection	7582524
80010863	80010886	6	+	27260156	MEWO	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.4468262382225373	[312]	[278,192,184]	-7	hSpCas9	negative selection	7582525
80007853	80007876	6	-	27260156	MEWO	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	0.012365654591937725	[377]	[388,405,280]	0	hSpCas9	negative selection	7582526
80008396	80008419	6	-	27260156	LNCAPCLONEFGC	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	0.045882666831874364	[1895]	[1739,1497,2098,1820]	0	hSpCas9	negative selection	7639526
80007958	80007981	6	+	27260156	LNCAPCLONEFGC	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.4969145570298046	[141]	[179,189,218,141]	7	hSpCas9	negative selection	7639527
80008404	80008427	6	+	27260156	LNCAPCLONEFGC	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.132334471811546	[885]	[895,743,1008,896]	2	hSpCas9	negative selection	7639528
80010840	80010863	6	+	27260156	LNCAPCLONEFGC	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	-0.007151209518888063	[419]	[488,230,427,380]	0	hSpCas9	negative selection	7703775
80010863	80010886	6	+	27260156	LNCAPCLONEFGC	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.0812037220064958	[312]	[170,116,97,144]	-9	hSpCas9	negative selection	7703776
80007853	80007876	6	-	27260156	LNCAPCLONEFGC	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.589574241132929	[377]	[230,189,237,254]	-7	hSpCas9	negative selection	7703777
80008396	80008419	6	-	27260156	PANC0327	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.4639961141685913	[1895]	[1498,912,1121,1411]	-6	hSpCas9	negative selection	7760777
80007958	80007981	6	+	27260156	PANC0327	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.10033571181680356	[141]	[200,90,148,110]	1	hSpCas9	negative selection	7760778
80008404	80008427	6	+	27260156	PANC0327	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.5526560490883123	[885]	[460,410,529,753]	-7	hSpCas9	negative selection	7760779
80010840	80010863	6	+	27260156	PANC0327	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.497689549574005	[419]	[610,322,489,715]	7	hSpCas9	negative selection	7825026
80010863	80010886	6	+	27260156	PANC0327	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.247195531317474	[312]	[66,80,126,193]	-9	hSpCas9	negative selection	7825027
80007853	80007876	6	-	27260156	PANC0327	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.4153728285789778	[377]	[474,83,249,237]	-6	hSpCas9	negative selection	7825028
80008396	80008419	6	-	27260156	NCIH2009	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.1258835446316824	[1895]	[2575,2272,2461]	-2	hSpCas9	negative selection	7882028
80007958	80007981	6	+	27260156	NCIH2009	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.12723576811597348	[141]	[301,149,116]	-2	hSpCas9	negative selection	7882029
80008404	80008427	6	+	27260156	NCIH2009	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.7299826748828151	[885]	[845,769,640]	-7	hSpCas9	negative selection	7882030
80010840	80010863	6	+	27260156	NCIH2009	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	-0.3453158685170855	[419]	[482,465,439]	-5	hSpCas9	negative selection	7946277
80010863	80010886	6	+	27260156	NCIH2009	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.8071396002563849	[312]	[99,110,158]	-9	hSpCas9	negative selection	7946278
80007853	80007876	6	-	27260156	NCIH2009	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.6441569555826987	[377]	[301,233,471]	-7	hSpCas9	negative selection	7946279
80008396	80008419	6	-	27260156	NCIH1373	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.41015500180436115	[1895]	[2227,1673,1242,347]	-4	hSpCas9	negative selection	8003279
80007958	80007981	6	+	27260156	NCIH1373	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.007667078237894698	[141]	[165,100,309,13]	0	hSpCas9	negative selection	8003280
80008404	80008427	6	+	27260156	NCIH1373	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.9349936702827192	[885]	[629,518,640,74]	-7	hSpCas9	negative selection	8003281
80010840	80010863	6	+	27260156	NCIH1373	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.12893333298177134	[419]	[749,327,433,159]	1	hSpCas9	negative selection	8067528
80010863	80010886	6	+	27260156	NCIH1373	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.9189150270941	[312]	[193,60,61,18]	-9	hSpCas9	negative selection	8067529
80007853	80007876	6	-	27260156	NCIH1373	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.8087952387698729	[377]	[107,293,313,57]	-7	hSpCas9	negative selection	8067530
80008396	80008419	6	-	27260156	PATU8902	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.7302879780763305	[1895]	[2178,1401,1010,1946]	-6	hSpCas9	negative selection	8124530
80007958	80007981	6	+	27260156	PATU8902	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.3475054971634519	[141]	[207,90,182,126]	-3	hSpCas9	negative selection	8124531
80008404	80008427	6	+	27260156	PATU8902	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-1.034015330160971	[885]	[497,725,753,360]	-7	hSpCas9	negative selection	8124532
80010840	80010863	6	+	27260156	PATU8902	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.5212868396872667	[419]	[1016,1027,462,952]	5	hSpCas9	negative selection	8188779
80010863	80010886	6	+	27260156	PATU8902	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-2.8873481435798833	[312]	[95,33,83,7]	-9	hSpCas9	negative selection	8188780
80007853	80007876	6	-	27260156	PATU8902	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.6236062571557754	[377]	[525,243,180,466]	-6	hSpCas9	negative selection	8188781
80008396	80008419	6	-	27260156	PANC1	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	0.135589072388286	[1895]	[1794,2561,1450,1518]	2	hSpCas9	negative selection	8245781
80007958	80007981	6	+	27260156	PANC1	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.891233380691399	[141]	[263,224,186,223]	9	hSpCas9	negative selection	8245782
80008404	80008427	6	+	27260156	PANC1	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.2862771979222878	[885]	[543,969,565,498]	-4	hSpCas9	negative selection	8245783
80010840	80010863	6	+	27260156	PANC1	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	-0.190984117690869	[419]	[343,339,271,307]	-3	hSpCas9	negative selection	8310030
80010863	80010886	6	+	27260156	PANC1	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-2.2731907713166772	[312]	[91,39,73,17]	-9	hSpCas9	negative selection	8310031
80007853	80007876	6	-	27260156	PANC1	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.8748863169876533	[377]	[135,280,158,154]	-8	hSpCas9	negative selection	8310032
80008396	80008419	6	-	27260156	PANC0813	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.6139914072143935	[1895]	[2034,1399,1380,1076]	-7	hSpCas9	negative selection	8367032
80007958	80007981	6	+	27260156	PANC0813	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.49403426825329055	[141]	[112,176,85,97]	-6	hSpCas9	negative selection	8367033
80008404	80008427	6	+	27260156	PANC0813	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.5664390331924232	[885]	[791,782,532,708]	-7	hSpCas9	negative selection	8367034
80010840	80010863	6	+	27260156	PANC0813	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.18757532245133313	[419]	[605,478,675,493]	3	hSpCas9	negative selection	8431281
80010863	80010886	6	+	27260156	PANC0813	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.867271283731161	[312]	[137,74,120,73]	-9	hSpCas9	negative selection	8431282
80007853	80007876	6	-	27260156	PANC0813	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.2784770198185253	[377]	[305,503,407,246]	-4	hSpCas9	negative selection	8431283
80008396	80008419	6	-	27260156	RDES	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.10263832931106132	[1895]	[1585,1973,2234,2438]	-2	hSpCas9	negative selection	8488283
80007958	80007981	6	+	27260156	RDES	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	-0.34505077678528395	[141]	[137,127,111,128]	-5	hSpCas9	negative selection	8488284
80008404	80008427	6	+	27260156	RDES	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.5650074486327421	[885]	[564,600,793,835]	-7	hSpCas9	negative selection	8488285
80010840	80010863	6	+	27260156	RDES	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.171665673948697	[419]	[489,499,514,690]	2	hSpCas9	negative selection	8552532
80010863	80010886	6	+	27260156	RDES	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.5929471840818037	[312]	[171,105,89,87]	-9	hSpCas9	negative selection	8552533
80007853	80007876	6	-	27260156	RDES	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.5412977332252749	[377]	[192,406,236,369]	-7	hSpCas9	negative selection	8552534
80008396	80008419	6	-	27260156	PC3	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.18808994704843385	[1895]	[1029,1600,2695,1838]	-4	hSpCas9	negative selection	8609534
80007958	80007981	6	+	27260156	PC3	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.7628615834619757	[141]	[107,369,300,236]	9	hSpCas9	negative selection	8609535
80008404	80008427	6	+	27260156	PC3	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.44021362800174435	[885]	[700,1229,2398,1029]	8	hSpCas9	negative selection	8609536
80010840	80010863	6	+	27260156	PC3	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.2043742136619375	[419]	[306,459,724,565]	4	hSpCas9	negative selection	8673783
80010863	80010886	6	+	27260156	PC3	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.728473789204572	[312]	[168,154,342,128]	-9	hSpCas9	negative selection	8673784
80007853	80007876	6	-	27260156	PC3	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.6005021557787478	[377]	[127,288,513,193]	-8	hSpCas9	negative selection	8673785
80008396	80008419	6	-	27260156	PATU8988T	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.03652403757342371	[1895]	[1558,2250,1858,1494]	0	hSpCas9	negative selection	8730785
80007958	80007981	6	+	27260156	PATU8988T	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.5294423227856344	[141]	[189,214,120,274]	8	hSpCas9	negative selection	8730786
80008404	80008427	6	+	27260156	PATU8988T	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.12106129039162061	[885]	[708,536,688,1226]	-2	hSpCas9	negative selection	8730787
80010840	80010863	6	+	27260156	PATU8988T	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	-0.10306293740506553	[419]	[355,426,416,309]	-2	hSpCas9	negative selection	8795034
80010863	80010886	6	+	27260156	PATU8988T	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.6986375393036854	[312]	[40,157,94,83]	-9	hSpCas9	negative selection	8795035
80007853	80007876	6	-	27260156	PATU8988T	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.40505465248143985	[377]	[364,195,357,166]	-6	hSpCas9	negative selection	8795036
80008396	80008419	6	-	27260156	T47D	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.10080766468407831	[1895]	[2080,1875,2104,2195]	-2	hSpCas9	negative selection	8852036
80007958	80007981	6	+	27260156	T47D	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.34372073208395415	[141]	[202,271,193,163]	7	hSpCas9	negative selection	8852037
80008404	80008427	6	+	27260156	T47D	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.3338524564453389	[885]	[1204,1291,1444,1257]	7	hSpCas9	negative selection	8852038
80010840	80010863	6	+	27260156	T47D	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.156214158222749	[419]	[508,540,511,621]	3	hSpCas9	negative selection	8916285
80010863	80010886	6	+	27260156	T47D	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.6543089200863822	[312]	[253,149,293,234]	-8	hSpCas9	negative selection	8916286
80007853	80007876	6	-	27260156	T47D	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.23980432430415916	[377]	[404,289,430,371]	-5	hSpCas9	negative selection	8916287
80008396	80008419	6	-	27260156	SU8686	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.4780172035965069	[1895]	[1367,1229,1218,1625]	-6	hSpCas9	negative selection	8973287
80007958	80007981	6	+	27260156	SU8686	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.0444883667640632	[141]	[124,180,92,182]	0	hSpCas9	negative selection	8973288
80008404	80008427	6	+	27260156	SU8686	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.5921970073721047	[885]	[612,681,424,585]	-7	hSpCas9	negative selection	8973289
80010840	80010863	6	+	27260156	SU8686	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.5727656290473893	[419]	[480,644,535,859]	8	hSpCas9	negative selection	9037536
80010863	80010886	6	+	27260156	SU8686	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-1.4022730497032359	[312]	[141,84,146,92]	-9	hSpCas9	negative selection	9037537
80007853	80007876	6	-	27260156	SU8686	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.7348982749619795	[377]	[263,162,172,315]	-8	hSpCas9	negative selection	9037538
80008396	80008419	6	-	27260156	SKES1	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.27434873601216236	[1895]	[1660,1667,1612,1347]	-6	hSpCas9	negative selection	9094538
80007958	80007981	6	+	27260156	SKES1	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.203391850042415	[141]	[136,163,152,189]	4	hSpCas9	negative selection	9094539
80008404	80008427	6	+	27260156	SKES1	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.31537058871833223	[885]	[691,1019,555,613]	-6	hSpCas9	negative selection	9094540
80010840	80010863	6	+	27260156	SKES1	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.29233119580879163	[419]	[562,543,547,413]	6	hSpCas9	negative selection	9158787
80010863	80010886	6	+	27260156	SKES1	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.6464675974208108	[312]	[295,205,201,115]	-8	hSpCas9	negative selection	9158788
80007853	80007876	6	-	27260156	SKES1	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.7740345674193865	[377]	[277,208,170,227]	-9	hSpCas9	negative selection	9158789
80008396	80008419	6	-	27260156	TOV112D	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.2517828285156396	[1895]	[1735,1924,1436,1377]	-5	hSpCas9	negative selection	9215789
80007958	80007981	6	+	27260156	TOV112D	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.13014235827674248	[141]	[211,278,103,64]	2	hSpCas9	negative selection	9215790
80008404	80008427	6	+	27260156	TOV112D	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.02847641102920595	[885]	[667,940,816,1173]	0	hSpCas9	negative selection	9215791
80010840	80010863	6	+	27260156	TOV112D	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.05617143427527485	[419]	[551,265,490,407]	1	hSpCas9	negative selection	9280038
80010863	80010886	6	+	27260156	TOV112D	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.34445412269234754	[312]	[384,283,165,174]	-6	hSpCas9	negative selection	9280039
80007853	80007876	6	-	27260156	TOV112D	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.7268581930847464	[377]	[238,285,118,283]	-9	hSpCas9	negative selection	9280040
80008396	80008419	6	-	27260156	TC71	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.19220576158323222	[1895]	[1948,1676,1697,1790]	-5	hSpCas9	negative selection	9337040
80007958	80007981	6	+	27260156	TC71	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.3353216733980644	[141]	[216,224,139,186]	7	hSpCas9	negative selection	9337041
80008404	80008427	6	+	27260156	TC71	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	0.2435676506404485	[885]	[1028,1117,1178,1174]	6	hSpCas9	negative selection	9337042
80010840	80010863	6	+	27260156	TC71	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.04643756699643799	[419]	[353,411,485,618]	1	hSpCas9	negative selection	9401289
80010863	80010886	6	+	27260156	TC71	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.3523673263800511	[312]	[217,311,222,302]	-7	hSpCas9	negative selection	9401290
80007853	80007876	6	-	27260156	TC71	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.17042739295104276	[377]	[351,342,349,397]	-4	hSpCas9	negative selection	9401291
80008396	80008419	6	-	27260156	TC32	viability	AAGTAGTCACGTGCATCATCTGG	TTK	ENSG00000112742	-0.05134549392541099	[1895]	[1584,1471,2149,1750]	-1	hSpCas9	negative selection	9458291
80007958	80007981	6	+	27260156	TC32	viability	GCGCTTCCCCCAGATAAATATGG	TTK	ENSG00000112742	0.12471881362929937	[141]	[133,118,137,194]	2	hSpCas9	negative selection	9458292
80008404	80008427	6	+	27260156	TC32	viability	TGCACGTGACTACTTTCAAATGG	TTK	ENSG00000112742	-0.09134976880549872	[885]	[656,558,1012,1004]	-2	hSpCas9	negative selection	9458293
80010840	80010863	6	+	27260156	TC32	viability	CTTCAAAAAGCTGTAGAACGTGG	TTK	ENSG00000112742	0.21847623907268388	[419]	[395,292,654,578]	4	hSpCas9	negative selection	9522540
80010863	80010886	6	+	27260156	TC32	viability	AGCAGTACCACTAGAAATGCTGG	TTK	ENSG00000112742	-0.6943158591933453	[312]	[129,115,300,224]	-8	hSpCas9	negative selection	9522541
80007853	80007876	6	-	27260156	TC32	viability	AACAAACTCAACCAGTCCTCTGG	TTK	ENSG00000112742	-0.20869679702116312	[377]	[295,211,342,409]	-4	hSpCas9	negative selection	9522542
80007842	80007865	6	+	27869803	HPAFII	viability after 27 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-3.380257985591539	[703]	[76,0,NaN]	-9	hSpCas9	negative selection	9596899
80011467	80011490	6	-	27869803	HPAFII	viability after 27 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.5147922646877585	[737]	[447,642,NaN]	4	hSpCas9	negative selection	9596900
80007842	80007865	6	+	27869803	HPAFII	viability after 15 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-3.9188871426818777	[703]	[115,8,NaN]	-9	hSpCas9	negative selection	9679348
80011467	80011490	6	-	27869803	HPAFII	viability after 15 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.333851166405738	[737]	[1167,894,NaN]	4	hSpCas9	negative selection	9679349
80007842	80007865	6	+	27869803	ASPC1	viability after 36 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-3.156209408149019	[1791]	[56,36,104]	-9	hSpCas9	negative selection	9761797
80011467	80011490	6	-	27869803	ASPC1	viability after 36 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.9904932147050971	[1797]	[1680,1331,861]	8	hSpCas9	negative selection	9761798
80007842	80007865	6	+	27869803	PATU8988S	viability after 35 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-2.719623936548274	[1276]	[112,42,NaN]	-9	hSpCas9	negative selection	9844246
80011467	80011490	6	-	27869803	PATU8988S	viability after 35 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.7188276172609178	[1482]	[1213,750,NaN]	7	hSpCas9	negative selection	9844247
80007842	80007865	6	+	27869803	PATU8988S	viability after 31 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-2.5085340081546574	[1276]	[103,70,NaN]	-9	hSpCas9	negative selection	9926695
80011467	80011490	6	-	27869803	PATU8988S	viability after 31 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.7705829372404536	[1482]	[988,1033,NaN]	8	hSpCas9	negative selection	9926696
80007842	80007865	6	+	27869803	HPAFII	viability after 35 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-4.1505760956053095	[703]	[36,0,NaN]	-9	hSpCas9	negative selection	10009144
80011467	80011490	6	-	27869803	HPAFII	viability after 35 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.0037303430369675095	[737]	[232,533,NaN]	0	hSpCas9	negative selection	10009145
80007842	80007865	6	+	27869803	HPAFII	viability after 31 days	TGGCAAACAACCCAGAGGACTGG	TTK	ENSG00000112742	-3.357668802958738	[703]	[72,0,NaN]	-9	hSpCas9	negative selection	10091593
80011467	80011490	6	-	27869803	HPAFII	viability after 31 days	CTGTAAATGCCCAAGTGAACCGG	TTK	ENSG00000112742	0.11554749920922203	[737]	[285,625,NaN]	0	hSpCas9	negative selection	10091594
80007837	80007860	6	+	28162770	P31FUJ	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-4.606260599941823	[227]	[10]	-9	hSpCas9	negative selection	10258959
80011515	80011538	6	+	28162770	P31FUJ	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	-1.2328022044143783	[89]	[44]	-7	hSpCas9	negative selection	10258960
80022354	80022377	6	+	28162770	P31FUJ	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-1.4478150953852291	[194]	[83]	-7	hSpCas9	negative selection	10258961
80027916	80027939	6	-	28162770	P31FUJ	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-2.1130248495608175	[334]	[90]	-8	hSpCas9	negative selection	10258962
80031527	80031550	6	+	28162770	P31FUJ	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-1.4164021427537674	[317]	[139]	-7	hSpCas9	negative selection	10258963
80010917	80010940	6	+	28162770	P31FUJ	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-1.643086173722588	[100]	[37]	-8	hSpCas9	negative selection	10258964
80011496	80011519	6	+	28162770	P31FUJ	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-0.6478397036932226	[107]	[80]	-5	hSpCas9	negative selection	10258965
80022451	80022474	6	+	28162770	P31FUJ	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-2.6922338230516756	[175]	[31]	-9	hSpCas9	negative selection	10258966
80027948	80027971	6	-	28162770	P31FUJ	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-0.5379870354671646	[256]	[207]	-4	hSpCas9	negative selection	10258967
80010877	80010900	6	+	28162770	P31FUJ	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-1.8582925117181452	[360]	[116]	-8	hSpCas9	negative selection	10258968
80007837	80007860	6	+	28162770	TF1	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10428325
80011515	80011538	6	+	28162770	TF1	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10428326
80022354	80022377	6	+	28162770	TF1	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10428327
80027916	80027939	6	-	28162770	TF1	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	NaN	[NaN]	[147]	1	hSpCas9	negative selection	10428328
80031527	80031550	6	+	28162770	TF1	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	NaN	[NaN]	[104]	1	hSpCas9	negative selection	10428329
80010917	80010940	6	+	28162770	TF1	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10428330
80011496	80011519	6	+	28162770	TF1	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10428331
80022451	80022474	6	+	28162770	TF1	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10428332
80027948	80027971	6	-	28162770	TF1	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10428333
80010877	80010900	6	+	28162770	TF1	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10428334
80007837	80007860	6	+	28162770	SKM1	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-4.728892293630524	[74]	[4]	-9	hSpCas9	negative selection	10597691
80011515	80011538	6	+	28162770	SKM1	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	0.8102665174775074	[19]	[61]	7	hSpCas9	negative selection	10597692
80022354	80022377	6	+	28162770	SKM1	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-0.3123273246050865	[58]	[83]	-3	hSpCas9	negative selection	10597693
80027916	80027939	6	-	28162770	SKM1	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-0.7524607647689285	[80]	[84]	-5	hSpCas9	negative selection	10597694
80031527	80031550	6	+	28162770	SKM1	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-0.3480705096895934	[89]	[124]	-3	hSpCas9	negative selection	10597695
80010917	80010940	6	+	28162770	SKM1	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-2.959505221771941	[21]	[4]	-9	hSpCas9	negative selection	10597696
80011496	80011519	6	+	28162770	SKM1	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	1.8333501305905484	[9]	[62]	9	hSpCas9	negative selection	10597697
80022451	80022474	6	+	28162770	SKM1	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-2.19546009354945	[56]	[21]	-8	hSpCas9	negative selection	10597698
80027948	80027971	6	-	28162770	SKM1	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-0.027320605999512027	[48]	[84]	0	hSpCas9	negative selection	10597699
80010877	80010900	6	+	28162770	SKM1	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-0.7049622768317861	[70]	[76]	-5	hSpCas9	negative selection	10597700
80007837	80007860	6	+	28162770	SKM1	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-4.728892293630524	[74]	[4]	-9	hSpCas9	negative selection	10767057
80011515	80011538	6	+	28162770	SKM1	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	0.8102665174775074	[19]	[61]	7	hSpCas9	negative selection	10767058
80022354	80022377	6	+	28162770	SKM1	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-0.3123273246050865	[58]	[83]	-3	hSpCas9	negative selection	10767059
80027916	80027939	6	-	28162770	SKM1	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-0.7524607647689285	[80]	[84]	-5	hSpCas9	negative selection	10767060
80031527	80031550	6	+	28162770	SKM1	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-0.3480705096895934	[89]	[124]	-3	hSpCas9	negative selection	10767061
80010917	80010940	6	+	28162770	SKM1	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-2.959505221771941	[21]	[4]	-9	hSpCas9	negative selection	10767062
80011496	80011519	6	+	28162770	SKM1	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	1.8333501305905484	[9]	[62]	9	hSpCas9	negative selection	10767063
80022451	80022474	6	+	28162770	SKM1	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-2.19546009354945	[56]	[21]	-8	hSpCas9	negative selection	10767064
80027948	80027971	6	-	28162770	SKM1	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-0.027320605999512027	[48]	[84]	0	hSpCas9	negative selection	10767065
80010877	80010900	6	+	28162770	SKM1	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-0.7049622768317861	[70]	[76]	-5	hSpCas9	negative selection	10767066
80007837	80007860	6	+	28162770	PL21	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-2.1970766077022796	[294]	[27]	-8	hSpCas9	negative selection	10936423
80011515	80011538	6	+	28162770	PL21	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	-0.30465253754785293	[104]	[36]	-2	hSpCas9	negative selection	10936424
80022354	80022377	6	+	28162770	PL21	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	0.6913876803882826	[211]	[148]	6	hSpCas9	negative selection	10936425
80027916	80027939	6	-	28162770	PL21	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-0.2101443548188891	[302]	[113]	-1	hSpCas9	negative selection	10936426
80031527	80031550	6	+	28162770	PL21	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	0.06178469204787751	[338]	[153]	0	hSpCas9	negative selection	10936427
80010917	80010940	6	+	28162770	PL21	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-1.3482970102067222	[116]	[19]	-7	hSpCas9	negative selection	10936428
80011496	80011519	6	+	28162770	PL21	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-0.969785386952992	[62]	[13]	-6	hSpCas9	negative selection	10936429
80022451	80022474	6	+	28162770	PL21	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.5423641632183158	[173]	[25]	-7	hSpCas9	negative selection	10936430
80027948	80027971	6	-	28162770	PL21	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	0.7903770572511506	[181]	[136]	6	hSpCas9	negative selection	10936431
80010877	80010900	6	+	28162770	PL21	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-0.6013147061285997	[243]	[69]	-4	hSpCas9	negative selection	10936432
80007837	80007860	6	+	28162770	P31FUJ	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-4.606260599941823	[227]	[10]	-9	hSpCas9	negative selection	11105789
80011515	80011538	6	+	28162770	P31FUJ	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	-1.2328022044143783	[89]	[44]	-7	hSpCas9	negative selection	11105790
80022354	80022377	6	+	28162770	P31FUJ	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-1.4478150953852291	[194]	[83]	-7	hSpCas9	negative selection	11105791
80027916	80027939	6	-	28162770	P31FUJ	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-2.1130248495608175	[334]	[90]	-8	hSpCas9	negative selection	11105792
80031527	80031550	6	+	28162770	P31FUJ	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-1.4164021427537674	[317]	[139]	-7	hSpCas9	negative selection	11105793
80010917	80010940	6	+	28162770	P31FUJ	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-1.643086173722588	[100]	[37]	-8	hSpCas9	negative selection	11105794
80011496	80011519	6	+	28162770	P31FUJ	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-0.6478397036932226	[107]	[80]	-5	hSpCas9	negative selection	11105795
80022451	80022474	6	+	28162770	P31FUJ	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-2.6922338230516756	[175]	[31]	-9	hSpCas9	negative selection	11105796
80027948	80027971	6	-	28162770	P31FUJ	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-0.5379870354671646	[256]	[207]	-4	hSpCas9	negative selection	11105797
80010877	80010900	6	+	28162770	P31FUJ	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-1.8582925117181452	[360]	[116]	-8	hSpCas9	negative selection	11105798
80007837	80007860	6	+	28162770	OCIAML5	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-4.678037171088948	[155]	[10]	-9	hSpCas9	negative selection	11275155
80011515	80011538	6	+	28162770	OCIAML5	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	-0.6472467789754988	[58]	[67]	-4	hSpCas9	negative selection	11275156
80022354	80022377	6	+	28162770	OCIAML5	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-0.5116421323592453	[123]	[156]	-4	hSpCas9	negative selection	11275157
80027916	80027939	6	-	28162770	OCIAML5	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-0.534096489545318	[145]	[181]	-4	hSpCas9	negative selection	11275158
80031527	80031550	6	+	28162770	OCIAML5	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-1.5069310848153095	[147]	[93]	-7	hSpCas9	negative selection	11275159
80010917	80010940	6	+	28162770	OCIAML5	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-4.693368824844939	[42]	[2]	-9	hSpCas9	negative selection	11275160
80011496	80011519	6	+	28162770	OCIAML5	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-0.9315010383584019	[55]	[52]	-5	hSpCas9	negative selection	11275161
80022451	80022474	6	+	28162770	OCIAML5	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-2.3565391537247855	[121]	[42]	-8	hSpCas9	negative selection	11275162
80027948	80027971	6	-	28162770	OCIAML5	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-1.50414326744369	[131]	[83]	-7	hSpCas9	negative selection	11275163
80010877	80010900	6	+	28162770	OCIAML5	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-1.3801667346294768	[198]	[137]	-7	hSpCas9	negative selection	11275164
80007837	80007860	6	+	28162770	EOL1	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-1.7547421116987747	[473]	[73]	-8	hSpCas9	negative selection	11444521
80011515	80011538	6	+	28162770	EOL1	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	0.7109522984712455	[108]	[93]	6	hSpCas9	negative selection	11444522
80022354	80022377	6	+	28162770	EOL1	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-0.7608166261084595	[356]	[110]	-5	hSpCas9	negative selection	11444523
80027916	80027939	6	-	28162770	EOL1	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-0.8512370714861996	[451]	[131]	-5	hSpCas9	negative selection	11444524
80031527	80031550	6	+	28162770	EOL1	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-0.24607100004186244	[519]	[230]	-2	hSpCas9	negative selection	11444525
80010917	80010940	6	+	28162770	EOL1	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-0.2453772298717778	[179]	[79]	-2	hSpCas9	negative selection	11444526
80011496	80011519	6	+	28162770	EOL1	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-0.3973803233168278	[79]	[31]	-3	hSpCas9	negative selection	11444527
80022451	80022474	6	+	28162770	EOL1	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-0.18734510850036268	[200]	[92]	-1	hSpCas9	negative selection	11444528
80027948	80027971	6	-	28162770	EOL1	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	0.4377195892236806	[205]	[146]	4	hSpCas9	negative selection	11444529
80010877	80010900	6	+	28162770	EOL1	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-0.25515825066436315	[332]	[146]	-2	hSpCas9	negative selection	11444530
80007837	80007860	6	+	28162770	MOLM13	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-4.168251843102141	[372]	[14]	-9	hSpCas9	negative selection	11613887
80011515	80011538	6	+	28162770	MOLM13	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	0.40251337269255477	[157]	[150]	3	hSpCas9	negative selection	11613888
80022354	80022377	6	+	28162770	MOLM13	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-0.7458173119256469	[275]	[118]	-4	hSpCas9	negative selection	11613889
80027916	80027939	6	-	28162770	MOLM13	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	0.23051985910413209	[467]	[396]	1	hSpCas9	negative selection	11613890
80031527	80031550	6	+	28162770	MOLM13	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-0.9389807968628663	[410]	[154]	-5	hSpCas9	negative selection	11613891
80010917	80010940	6	+	28162770	MOLM13	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	0.8110339623416368	[107]	[136]	6	hSpCas9	negative selection	11613892
80011496	80011519	6	+	28162770	MOLM13	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-1.4118163847377092	[91]	[24]	-6	hSpCas9	negative selection	11613893
80022451	80022474	6	+	28162770	MOLM13	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.2735776048565681	[320]	[95]	-6	hSpCas9	negative selection	11613894
80027948	80027971	6	-	28162770	MOLM13	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-1.1356887973439245	[233]	[76]	-5	hSpCas9	negative selection	11613895
80010877	80010900	6	+	28162770	MOLM13	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-2.097444312427645	[437]	[73]	-7	hSpCas9	negative selection	11613896
80007837	80007860	6	+	28162770	HEL	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-2.726494977665362	[340]	[32]	-8	hSpCas9	negative selection	11783253
80011515	80011538	6	+	28162770	HEL	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	0.7537701443891007	[149]	[161]	6	hSpCas9	negative selection	11783254
80022354	80022377	6	+	28162770	HEL	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	0.7436677408511377	[206]	[221]	6	hSpCas9	negative selection	11783255
80027916	80027939	6	-	28162770	HEL	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	0.26265393155593786	[366]	[281]	2	hSpCas9	negative selection	11783256
80031527	80031550	6	+	28162770	HEL	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-0.04440406352727727	[350]	[217]	0	hSpCas9	negative selection	11783257
80010917	80010940	6	+	28162770	HEL	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-1.8079225770092084	[81]	[14]	-7	hSpCas9	negative selection	11783258
80011496	80011519	6	+	28162770	HEL	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-1.2317302859157842	[87]	[23]	-6	hSpCas9	negative selection	11783259
80022451	80022474	6	+	28162770	HEL	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-2.179262866021648	[296]	[41]	-8	hSpCas9	negative selection	11783260
80027948	80027971	6	-	28162770	HEL	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-0.8686008055776195	[190]	[66]	-5	hSpCas9	negative selection	11783261
80010877	80010900	6	+	28162770	HEL	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-1.183231768224594	[350]	[98]	-6	hSpCas9	negative selection	11783262
80007837	80007860	6	+	28162770	MV411	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-1.961279933656596	[244]	[52]	-8	hSpCas9	negative selection	11952619
80011515	80011538	6	+	28162770	MV411	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	-0.3276771639820337	[72]	[48]	-2	hSpCas9	negative selection	11952620
80022354	80022377	6	+	28162770	MV411	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-1.2416005299398452	[159]	[56]	-7	hSpCas9	negative selection	11952621
80027916	80027939	6	-	28162770	MV411	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-0.42450825153302085	[281]	[176]	-3	hSpCas9	negative selection	11952622
80031527	80031550	6	+	28162770	MV411	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-0.16012869906493332	[320]	[241]	-1	hSpCas9	negative selection	11952623
80010917	80010940	6	+	28162770	MV411	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-1.9954189731133885	[70]	[14]	-8	hSpCas9	negative selection	11952624
80011496	80011519	6	+	28162770	MV411	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-0.3105579023381113	[52]	[35]	-2	hSpCas9	negative selection	11952625
80022451	80022474	6	+	28162770	MV411	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.337524949938381	[119]	[39]	-7	hSpCas9	negative selection	11952626
80027948	80027971	6	-	28162770	MV411	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-0.6412454263530665	[186]	[100]	-4	hSpCas9	negative selection	11952627
80010877	80010900	6	+	28162770	MV411	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-0.8479820142959071	[249]	[116]	-5	hSpCas9	negative selection	11952628
80007837	80007860	6	+	28162770	MONOMAC1	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-2.518964941946916	[149]	[29]	-9	hSpCas9	negative selection	12121985
80011515	80011538	6	+	28162770	MONOMAC1	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	-1.6995371875887373	[67]	[23]	-8	hSpCas9	negative selection	12121986
80022354	80022377	6	+	28162770	MONOMAC1	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-1.2263808086416983	[148]	[72]	-7	hSpCas9	negative selection	12121987
80027916	80027939	6	-	28162770	MONOMAC1	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-0.5878268000917202	[176]	[134]	-5	hSpCas9	negative selection	12121988
80031527	80031550	6	+	28162770	MONOMAC1	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-0.4163498754640296	[233]	[200]	-4	hSpCas9	negative selection	12121989
80010917	80010940	6	+	28162770	MONOMAC1	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-1.0219501405014626	[61]	[34]	-7	hSpCas9	negative selection	12121990
80011496	80011519	6	+	28162770	MONOMAC1	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-0.012612275922126326	[43]	[49]	0	hSpCas9	negative selection	12121991
80022451	80022474	6	+	28162770	MONOMAC1	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.5389564171343821	[108]	[42]	-8	hSpCas9	negative selection	12121992
80027948	80027971	6	-	28162770	MONOMAC1	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-1.3535413327395445	[106]	[47]	-7	hSpCas9	negative selection	12121993
80010877	80010900	6	+	28162770	MONOMAC1	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	0.03956943349659503	[201]	[237]	0	hSpCas9	negative selection	12121994
80007837	80007860	6	+	28162770	OCIAML2	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-2.631094497435407	[56]	[50]	-9	hSpCas9	negative selection	12291351
80011515	80011538	6	+	28162770	OCIAML2	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	-0.6961895256572922	[18]	[64]	-5	hSpCas9	negative selection	12291352
80022354	80022377	6	+	28162770	OCIAML2	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	0.03956490707702274	[32]	[187]	0	hSpCas9	negative selection	12291353
80027916	80027939	6	-	28162770	OCIAML2	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-0.852308727574574	[56]	[174]	-5	hSpCas9	negative selection	12291354
80031527	80031550	6	+	28162770	OCIAML2	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-0.7078802053057224	[60]	[206]	-5	hSpCas9	negative selection	12291355
80010917	80010940	6	+	28162770	OCIAML2	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	-0.6632749031845568	[11]	[41]	-5	hSpCas9	negative selection	12291356
80011496	80011519	6	+	28162770	OCIAML2	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-0.31308854825568133	[12]	[57]	-3	hSpCas9	negative selection	12291357
80022451	80022474	6	+	28162770	OCIAML2	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.2565050198893137	[24]	[57]	-7	hSpCas9	negative selection	12291358
80027948	80027971	6	-	28162770	OCIAML2	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	-0.8719923876239286	[34]	[105]	-6	hSpCas9	negative selection	12291359
80010877	80010900	6	+	28162770	OCIAML2	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-2.01606396177668	[53]	[73]	-8	hSpCas9	negative selection	12291360
80007837	80007860	6	+	28162770	OCIAML3	viability	GATGATGGCAAACAACCCAGAGG	TTK	ENSG00000112742	-1.7159981647027736	[73]	[67]	-8	hSpCas9	negative selection	12460717
80011515	80011538	6	+	28162770	OCIAML3	viability	GAGGACAGACTACTAAAGCCAGG	TTK	ENSG00000112742	-1.3183731977107358	[37]	[45]	-7	hSpCas9	negative selection	12460718
80022354	80022377	6	+	28162770	OCIAML3	viability	CAGAGAGTAACCAGAAACAGTGG	TTK	ENSG00000112742	-0.00904513960300703	[51]	[155]	0	hSpCas9	negative selection	12460719
80027916	80027939	6	-	28162770	OCIAML3	viability	GTTGACAACTGACAAGCAGGTGG	TTK	ENSG00000112742	-1.4240826388818508	[103]	[116]	-7	hSpCas9	negative selection	12460720
80031527	80031550	6	+	28162770	OCIAML3	viability	TTAAAGCAGATAGGAAGTGGAGG	TTK	ENSG00000112742	-0.7866527182665591	[103]	[181]	-5	hSpCas9	negative selection	12460721
80010917	80010940	6	+	28162770	OCIAML3	viability	AAAGCAGCTGCTTTCAGAGGAGG	TTK	ENSG00000112742	1.8051634534956598	[19]	[210]	9	hSpCas9	negative selection	12460722
80011496	80011519	6	+	28162770	OCIAML3	viability	AACAACAGTTGTGATTCCAGAGG	TTK	ENSG00000112742	-1.409583069186736	[21]	[24]	-7	hSpCas9	negative selection	12460723
80022451	80022474	6	+	28162770	OCIAML3	viability	AGCCCGAAAAGTTAATACAGAGG	TTK	ENSG00000112742	-1.5940076403241632	[51]	[51]	-8	hSpCas9	negative selection	12460724
80027948	80027971	6	-	28162770	OCIAML3	viability	GCTGCTGGAAACAGGCAGGTTGG	TTK	ENSG00000112742	0.20831169183614257	[40]	[142]	2	hSpCas9	negative selection	12460725
80010877	80010900	6	+	28162770	OCIAML3	viability	AAATGCTGGAAATTGCCCTGCGG	TTK	ENSG00000112742	-0.9648453356924718	[74]	[115]	-6	hSpCas9	negative selection	12460726